The Biology of Gastric Cancers [electronic resource] /
Wang, Timothy.editor.
Fox, James.editor.
Giraud, Andy.editor.
There have been many impressive advances in our understanding of the pathogenesis of gastric adenocarcinoma, gastric MALT lymphoma, gastrointestinal stromal tumors of the stomach, and gastric carcinoid tumors over the years. "The Biology of Gastric Cancers," edited by Dr. Timothy Wang, Dr. James Fox and Dr. Andy Giraud, pays homage to the cutting edge concepts of cancer stem cells, tumor microenvironment, chronic inflammation, and genetic susceptibility to cancer and represents the very first volume devoted to the subject of the basic biology of gastric cancer. With an emphasis on animal models, but also considerable attention to human studies, host genetics and the role of bacterial factors and other environmental factors influencing the pathogenesis of gastric cancer, the topics presented in this book should be of interest to clinicians and investigators interested in gastrointestinal cancer, as well as basic investigators in related areas of cancer research. This body of work will hopefully stimulate clinical and translational studies that will advance early diagnosis and treatment of gastric tumors.
Description based upon print version of record.
Includes bibliographical references and index.
Overview and Pathology of Gastric Cancer -- Epidemiology of Gastric Cancer and Helicobacter pylori -- Diet and Gastric Cancer -- MALT Lymphoma: Clinicopathologic Features and Molecular Pathogenesis -- Gastrointestinal Stromal Tumors of Gastric Origin -- Human Gastric Neuroendocrine Neoplasia: Current Pathologic Status -- Gastric Neuroendocrine Neoplasia -- Epstein-Barr Virus and Gastric Cancer -- Role of Host Genetic Susceptibility in the Pathogenesis of Gastric Cancer -- Cancer Genetics of Human Gastric Adenocarcinoma -- Genomic and Proteomic Advances in Gastric Cancer -- Animal Models of Gastric Carcinoma -- Insights into the Development of Preneoplastic Metaplasia: Spasmolytic Polypeptide-Expressing Metaplasia and Oxyntic Atrophy -- Deregulation of E-Cadherin in Precancerous Lesions and Gastric Cancer -- Role of CagA in Helicobacter pylori Infection and Pathology -- The Role of Helicobacter pylori Virulence Factors in Rodent and Primate Models of Disease -- Host Immunity in the Development of Gastric Preneoplasia -- Atrophy and Altered Mesenchymal—Epithelial Signaling Preceding Gastric Cancer -- Genetic Models of Gastric Cancer in the Mouse -- Prostaglandin and Transforming Growth Factor ? Signaling in Gastric Cancer -- REG Proteins and Other Growth Factors in Gastric Cancer -- Role of Bone Marrow—Derived Cells in Gastric Adenocarcinoma -- Stromal Cells and Tumor Microenvironment -- Future Prospects for Helicobacter pylori Vaccination.
There have been many impressive advances in our understanding of the pathogenesis of gastric adenocarcinoma, gastric MALT lymphoma, gastrointestinal stromal tumors of the stomach, and gastric carcinoid tumors over the years. "The Biology of Gastric Cancers," edited by Dr. Timothy Wang, Dr. James Fox and Dr. Andy Giraud, pays homage to the cutting edge concepts of cancer stem cells, tumor microenvironment, chronic inflammation, and genetic susceptibility to cancer and represents the very first volume devoted to the subject of the basic biology of gastric cancer. With an emphasis on animal models, but also considerable attention to human studies, host genetics and the role of bacterial factors and other environmental factors influencing the pathogenesis of gastric cancer, the topics presented in this book should be of interest to clinicians and investigators interested in gastrointestinal cancer, as well as basic investigators in related areas of cancer research. This body of work will hopefully stimulate clinical and translational studies that will advance early diagnosis and treatment of gastric tumors.
Cancer research.
Medicine.
Medical microbiology.
Human genetics.
Life sciences.
Cancer Research.
Biomedicine, general.
Medical Microbiology.
Human Genetics.
Life Sciences, general.