Stem Cells and Cancer Stem Cells, Volume 1 [electronic resource] : Stem Cells and Cancer Stem Cells, Therapeutic Applications in Disease and Injury: Volume 1 /
Hayat, M.A.editor.
Difference between tissue specific stem cells and embryonic stem cells is explained. The advantages of the latter are included. The application of human pluripotent stem cells, mesenchymal stem cells, and hematopoietic stem cells in cancer therapy and tissue/organ regeneration is detailed. Role of neural cancer stem cells in brain tumors, including their role in brain tumor therapy and the role of CD133 stem cell antigen in glioma patients, is emphasized. Therapeutic role of bone marrow-derived stem cells in myocardial infarction and the role of mesenchymal stem cells in orthopedics are explained. Transplantation of umbilical cord hematopoietic stem cells and allogeneic hematopoietic stem cell transplantation followed by graft-versus-host disease are presented. Role of cancer stem cells specifically in glioblastoma and medulloblastoma is included. It is also emphasized that CD133 is an appropriate stem cell marker for gliomas. Targeting of cancer cells is also explained.
Description based upon print version of record.
Preface; Contents; Contributors; Part I Introduction; 1 Pluripotent Human Stem Cells: An Overview; Introduction; Embryonic Stem Cells; Adult Stem Cells; Characterization of Pluripotency; Maintenance of Pluripotency; Pluripotency Spectrum; Manipulation of Pluripotency; Somatic Cell Nuclear Transfer; Induced Pluripotent Stem Cells; Molecular Mechanism of Pluripotency; Pluripotency in Clinical Application; Induced Pluripotent Stem Cells; Somatic Cell Nuclear Transfer; Comparison of ESC iPSC, and SCNT Therapies; Trans-Differentiation; Cancer in Relation to Stem Cells; Conclusion; References
2 Complexity of Tumor Angiogenesis and Stem CellsIntroduction; Special Features of Tumor Blood Vessels; Tumor-Associated Endothelial Cells (TECs); Bone Marrow (BM)-Derived Cells; Endothelial Progenitor Cells (EPCs); Hematopoietic Stem Cells (HSCs); Special Subgroups of BM-Derived Cells; Actual Contribution of BM-Derived Cells; Hematogenous Metastasis and Pre-metastatic Niche; Mesenchymal Stem Cells (MSCs); Tissue-Resident Vascular Progenitor Cells; Cancer-Associated Fibroblasts (CAFs); Chemokines in Tumor Angiogenesis and Metastasis; CXC Chemokines; CC Chemokines; References
3 Stem Cells Like Astrocytes: Various RolesIntroduction; Stem Cells in the Brain; Astrocytes and Their Relationship to Stem Cells; Cell of Origin for Brain Tumours; Reaction to Tumours; Potential for Tumour Therapy; Conclusion; References; Part II Neuronal Stem Cells; 4 Neural Crest Cell-Derived Tumors: An Overview; Introduction; Neural Crest Cell-Derived Tumors of the CNS; Tumors of Cranial and Peripheral Nerves; Schwannoma (ICD-O 9560/0); Malignant Peripheral Nerve Sheath Tumor (ICD-O 9540/3); Neurofibroma (ICD-O 9540/0); Perineurioma (ICD-O 9571/0)
Nerve Sheath Myxoma/Neurothecoma (ICD-O 9562/0)Granular Cell Tumor (ICD-O 9580/0); Melanocytic Tumors; Diffuse Melanocytosis (ICD-O 8728/0); Melanocytoma (ICD-O 8728/1); Malignant Melanoma (ICD-O 8720/3); Peripheral Neuroblastic Tumors; Olfactory Neuroblastoma (ICD-O 9522/3); Neuroblastic Tumors of the Sympathetic Nervous System and the Adrenal Gland; Embryonal Tumors of the CNS; Medulloblastoma (ICD-O 9470/3); Atypical Teratoid/Rhabdoid Tumor (ICD-O 9508/3); CNS PNET, Not Otherwise Specified (Supratentorial PNET (ICD-O 9473/3)); Medulloepithelioma (ICD-O 9501/3)
Ependymoblastoma (ICD-O 9392/3)Embryonal Tumor with Abundant Neuropil and True Rosettes (ETANTR); Paraganglioma Group; Paraganglioma (ICD-O 8680/1); Discussion; References; 5 Therapeutic Neural Stem Cells for Brain Tumor Therapy; Introduction; Neural Stem Cell Spurces and Their Genetic Modification; Transplantation Route and Fate of Neural Stem Cells; Therapeutic Applications for Brain Tumors; Diagnostic Potential of Engineered Neural Stem Cells; References; 6 Brain Tumors: Role of Neural Cancer Stem Cells; Introduction; Stem Cells; Neural Stem Cells; Cancer Stem Cells
Brain Cancer Stem Cells
Includes bibliographical references and index.
Difference between tissue specific stem cells and embryonic stem cells is explained. The advantages of the latter are included. The application of human pluripotent stem cells, mesenchymal stem cells, and hematopoietic stem cells in cancer therapy and tissue/organ regeneration is detailed. Role of neural cancer stem cells in brain tumors, including their role in brain tumor therapy and the role of CD133 stem cell antigen in glioma patients, is emphasized. Therapeutic role of bone marrow-derived stem cells in myocardial infarction and the role of mesenchymal stem cells in orthopedics are explained. Transplantation of umbilical cord hematopoietic stem cells and allogeneic hematopoietic stem cell transplantation followed by graft-versus-host disease are presented. Role of cancer stem cells specifically in glioblastoma and medulloblastoma is included. It is also emphasized that CD133 is an appropriate stem cell marker for gliomas. Targeting of cancer cells is also explained.
Oncology.
Radiology, Medical.
Neurosurgery.
Oncology  .
Pathology.
Transplantation of organs, tissu.
Cancer Research.
Neuroradiology.
Neurosurgery.
Oncology.
Pathology.
Transplant Surgery.