Diabetes and Pancreas Diabetes is linked to diseases of the exocrine pancreatitis which may disrupt the global architecture or physiology of Pancreas often resulting in both exocrine and endocrine dysfunction. Up to 1 of 2 patients with diabetes may have some degree of impaired exocrine pancreatic function. People with diabetes are at an approximately two fold higher risk of developing a Acute Pancreatitis. Conversely, pre-diabetes and /diabetes has been found to develop in approximately 1/3rd of the patient after an episode of acute pancreatitis.