prompter: What are the limitations of DNA editing? Could humans modify themselves at some point in the future to grow tails, wings or other body parts currently taken away from us by natural evolution?

assistant: There are a few limitations to the use of DNA editing technology such as CRISPR-Cas9. These limitations include:

1.  Risk of unintended mutations at sites other than the intended target.
2.  Possibility of having cells with unintended mutations persist and create variations within an individual.
3.  Ethical considerations that must be considered due to the permanent nature of DNA editing.

As for modifying humans to grow tails, wings, or other body parts that have been lost through evolution, it is not currently feasible and may remain so in the future. This is due to the intricate biological processes involved and likely ethical and safety concerns that would arise from such modifications.

prompter: How about doing the same to a lab mouse? That is using DNA editing to make lab mouse, for example, grow wings.

assistant: While it is possible to modify the DNA of a lab mouse using DNA editing technologies such as CRISPR-Cas9, creating wings in a mouse would be a highly complex and challenging task. This is because the process of growing wings involves a series of complex developmental steps, including the formation of bones, muscles, and feathers.

Additionally, even if the DNA was edited to allow for the formation of wings, it would not necessarily result in functional wings that could sustain flight. There would likely be other physiological and biomechanical considerations that would need to be addressed in order to achieve a functional, flight-capable mouse.

Overall, while DNA editing can be a powerful tool for studying genetic processes and understanding biological development, the creation of wings in a mouse would likely remain a hypothetical scenario for the near future.

prompter: Do you think a mouse with edited wings could fly? Wouldn't it be to heavy? What we should edit in order to make feasible for a mouse to fly?

assistant: Modifying lab mice to grow wings through DNA editing is also challenging for many of the same reasons that make it difficult for humans. The biological process of growing wings involves not just the genetic material but also complex physiological and developmental processes, and it is not clear that these could be mimicked or modified through DNA editing alone.

Additionally, even in mice, there would likely be safety concerns with any new or altered anatomy, such as the structural integrity of the wings and how they would interact with the rest of the mouse's body. Moreover, there would also be ethical considerations, such as the well-being of the mice themselves and the potential for their use in testing or other activities.

assistant: Yeah, that could work.

assistant: It is not yet known what the limitations of bio-engineering will be. However, it can be reasonably assumed that it will be possible to modify the human genome in a way that will result in the physical characteristics of contemporary organisms that have occurred through natural evolution. Various tails exist in the animal kingdom so it will likely be possible to bio-engineer humans with such tails. It would likely also be possible to bio-engineer humans with wings but they would likely not be functional unless the weight of the human were to be drastically reduced.

Physical characteristics that occurred in organisms as they existed millions of years ago may be more difficult to achieve. For example, in the Carboniferous period the oxygen levels of the atmosphere were much higher than they were today and it has been postulated that this allowed some animals to become much larger than they are today. So even if a physical characteristic from the distant past were to be recreated using modern technology it may be maladapted to the modern world.

Finally, physical characteristics that are not present in any known organism at all may be impossible to achieve via bio-engineering if said characteristics would be beneficial in terms of evolutionary fitness. This is because if such a characteristic were possible it would likely become dominant and thus be present in contemporary organisms. It may however be that the characteristic simply didn't occur by chance or that natural evolution would simply not result in such characteristics, for example because they would have resulted in a decrease of evolutionary fitness.

assistant: It's complicated to answer this question. The scientists are still in the process of evolving their knowledge around the DNA editing. Predicting the future of science is not in my capabilities.