1번 염색체

genbank_id = CM000663 **1번 염색체**는 인간에서 가장 큰 염색체이다. 인간은 이질염색체가 아닌 모든 상염색체와 마찬가지로 1번 염색체에 두 개의 사본을 가지고 있다. 1번 염색체는 DNA 정보의 기본 단위인 약 2억 4,900만 뉴클레오타이드 염기쌍에 걸쳐 있다.http://vega.sanger.ac.uk/Homo_sapiens/mapview?chr=1 Chromosome size and number of genes derived from this database, retrieved 2012-03-11. 그것은 인간 세포에 있는 전체 DNA의 약 8%를 차지한다.pmid=16710414 상염색체, 성염색체를 포함한 인간의 염색체 중에서 길이가 제일 길다. 1번 염색체의 단완의 일부가 결실되면 해당 부위의 유전자의 일부가 없어지는 유전병이 발생하는데 이를 **1번 단완 염색체 결실 증후군**이라고 한다. 해당 병에 걸리면 안면에 기형이 발생하며 발달장애, 운동장애 등을 동반하는 경우가 많다. 인종, 성별과 무관하게 1/5000에서 1/10000 정도의 확률로 발생한다.1번 단완 염색체 결실 증후군네이버 지식백과-건강백과 인간 유전체 프로젝트가 시작된 지 20년 후에 시퀀싱된 마지막 완성된 염색체였다.
# 유전자

## 유전자 수
다음은 인간 1번 염색체의 유전자 수 추정치 중 일부이다. 연구자들은 게놈 주석에 다른 접근 방식을 사용하기 때문에 각 염색체의 유전자 수에 대한 예측은 다양하다 (기술적인 세부 사항은 유전자 예측 참조). 다양한 프로젝트 중 CCDS (Collaborative Consensus coding sequence project)는 매우 보수적인 전략을 취한다. 따라서 CCDS의 유전자 수 예측은 인간 단백질 암호화 유전자의 총 수에 대한 하한을 나타낸다.pmid=20441615 {| class="wikitable" |- | CCDS | 1,961 | — | — | |확인날짜=2017-05-28 | 2016-09-08 |- | HGNC | 1,993 | 707 | 1,113 | |url-status= | 2017-05-12 |- | Ensembl | 2,044 | 1,924 | 1,223 | |확인날짜=2017-05-19 | 2017-03-29 |- | UniProt | 2,064 | — | — | |확인날짜=2018-03-16 | 2018-02-28 |- | NCBI | 2,093 | 1,790 | 1,426 | |확인날짜=2017-05-20확인날짜=2017-05-20확인날짜=2017-05-20 | 2017-05-19 |}
## 유전자 목록
다음은 인간 1번 염색체에 있는 유전자의 일부 목록이다. 전체 목록은 오른쪽 정보 상자의 링크를 참조하라. * C1orf112 : 암호화 단백질 염색체 1 오픈 리딩 프레임 112 * C1orf127 : 암호화 단백질 염색체 1 오픈 리딩 프레임 127 * C1orf27 : 암호화 단백질 염색체 1 오픈 리딩 프레임 27 * C1orf38 : 암호화 단백질 염색체 1 오픈 리딩 프레임 38 * CCDC181 : 암호화 단백질 코일된 코일 도메인 함유 단백질 181 * DENN1B : 천식과 관련이 있다고 가정됨 * FHAD1 : 단백질 1을 포함하는 단백질 포크헤드 관련 도메인 암호화 * LOC100132287 : 확실하지 않은 단백질 * LRRIQ3 : 암호화 단백질 류신이 풍부한 반복 및 3을 포함하는 IQ 모티브 * Shisa family member 4 : 암호화 단백질 시사 패밀리 구성원 4 * TINAGL1 : 항원 유사 세뇨관간질성 신염을 암호화하는 단백질
### p-arm
인간 1번 염색체의 p-arm (short arm)에 위치한 유전자의 일부 목록이다. * AADACL3: Arylacetamide deacetylase-like 3 * AADACL4: Arylacetamide deacetylase-like 4 * ACADM: acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain * ACTG1P6: encoding protein Actin, gamma 1 pseudogene 6 * ACTL8: Actin-like 8 * ADGRL2 (1p31.1): adhesion G protein-coupled receptor L2 * ADPRHL2: Poly(ADP-ribose) glycohydrolase ARH3 * AMPD2: encoding enzyme AMP deaminase 2 * ARID1A (1p36) * ATXN7L2: Ataxin 7-like 2 * AZIN2: encoding enzyme Antizyme inhibitor 2 (AzI2) also known as arginine decarboxylase (ADC) * BCAS2: Breast carcinoma amplified sequence 2 * BCL10 (1p22) * BCL2L15 (1p13) * LRIF1: encoding protein Ligand-dependent nuclear receptor-interacting factor 1 * C1orf109: chromosome 1 open reading frame 109 * CZIB: chromosome 1 open reading frame 123 * CACHD1 encoding protein Cache domain containing 1 * CAMTA1 (1p36) * CASP9 (1p36) * CASZ1 (1p36): Castor zinc finger 1 * CSDE1: Cold shock domain containing E1 * CHD5 (1p36) * CLIC4 (1p36) * CLSPN (1p34) * CMPK: UMP-CMP kinase * COL16A1 (1p35) * COL11A1: collagen, type XI, alpha 1 * CPT2: carnitine palmitoyltransferase II * CRYZ: Crystallin zeta * CYP4B1 (1p33) * CYR61 (1p22) * DBT: dihydrolipoamide branched chain transacylase E2 * DCLRE1B: DNA cross-link repair 1B * DEPDC1 encoding protein DEP domain containing 1 * DIRAS3 (1p31): DIRAS family, GTP-binding RAS-like 3 * DPH5: Diphthine synthase * DVL1 (1p36) * ENO1 (1p36) * EPHA2 (1p36) * EPS15 (1p32) * ESPN: espin (autosomal recessive deafness 36) * EVI5: ecotropic viral integration site 5 * EXTL1: exostosin like glycosyltransferase 1 * EXTL2: exostosin like glycosyltransferase 2 * FAM46B: family with sequence similarity 46, member B * FAM46C: family with sequence similarity 46, member C * FAM76A: family with sequence similarity 76, member A * FBXO2: F-box protein 2 * FNBP1L encoding protein Formin-binding protein 1-like * FPGT: Fucose-1-phosphate guanylyltransferase * FUBP1 (1p31) * GALE: UDP-galactose-4-epimerase * GADD45A (1p31) * GBP1 (1p22) * GBP2: guanylate binding protein 2 * GBP5 encoding protein Guanylate binding protein 5 * GJB3: gap junction protein, beta 3, 31kDa (connexin 31) * GLMN (1p22) * GNL2: G protein nucleolar 2 * GSTM1 (1p13) * HDAC1 (1p35) * HES2: Hes family bHLH transcription factor 2 * HES3: Hes family bHLH transcription factor 3 * HMGCL: 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase (hydroxymethylglutaricaciduria) * HAO2 encoding protein Hydroxyacid oxidase 2 * HMGCS2: 3-hydroxy-3-methylglutaryl-CoA synthase 2 * HP1BP3: Heterochromatin protein 1, binding protein 3 * IFI6: Interferon alpha-inducible protein 6 * IL22RA1 (1p36) * INTS11: Integrator complex subunit 11 * JAK1 (1p31) * JUN (1p32) * KCNQ4: potassium voltage-gated channel, KQT-like subfamily, member 4 * KIF1B: kinesin family member 1B * L1TD1: LINE-1 type transposase domain containing 1 * LCK (1p35) * LINC01137: encoding protein Long intergenic non-protein coding RNA 1137 * LRRC39: Leucine-rich repeat-containing protein 39 * LRRC40: Leucine-rich repeat-containing protein 40 * LRRC41: Leucine-rich repeat-containing protein 41 * LRRC8D: Leucine-rich repeat-containing protein 8D * MAN1A2: Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB * MEAF6: MYST/ESA1 associated factor 6 * MECR: Trans-2-enoyl-CoA reductase, mitochondrial * MFAP2: Microfibrillar-associated protein 2 * MIB2 (1p36) * MIER1 (1p31) * MFN2: mitofusin 2 * MFSD2: Major facilitator superfamily domain containing 2A * MIR6079: microRNA 6079 * MMEL1: Membrane metallo-endopeptidase-like 1 * MTFR1L: mitochondrial fission regulator 1 like * MTHFR (1p36): 5,10-methylenetetrahydrofolate reductase (NADPH) * MUL1: Mitochondrial E3 ubiquitin protein ligase 1 * MUTYH (1p34): mutY homolog (E. coli) * NBPF3: Neuroblastoma breakpoint family member 3 * NDUFA4P1: encoding protein Nadh dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kda, pseudogene 1 * NGF: Nerve Growth Factor * NOL9: Nucleolar protein 9 * NRAS (1p13) * NOTCH2 (1p12) * OLFML3: Olfactomedin-like 3 * OMA1: Metalloendopeptidase OMA1, mitochondrial * OVGP1: Oviductal glycoprotein 1 * PARK7 (1p36): Parkinson disease (autosomal recessive, early onset) 7 * PINK1: PTEN induced putative kinase 1 * PLOD1: procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1 * PRMT6: Protein arginine methyltransferase 6 * PSRC1: Proline/serine-rich coiled-coil protein 1 * RAD54L: RAD54-like * RAP1A (1p13) * RBM15 (1p13) * RCC2: Regulator of chromosome condensation 2 * REG4 (1p12) * RHBDL2: Rhomboid like 2 * RHOC (1p13) * RLF: rearranged L-myc fusion * RNF11 (1p32) * RNF220: RING finger protein 220 * RPA2 (1p35) * RSPO1 (1p34) * S100A1 (1q21) * SAMD11: encoding protein Sterile alpha motif domain containing 11 * SDC3: Syndecan-3 * SDHB (1p36) * SFPQ (1p34) * SGIP1: SH3 domain GRB2-like protein 3-interaction protein 1 * SH3BGRL3: SH3 domain-binding glutamic acid-rich-like protein 3 * SLC16A1 (1p13) * SPSB1: SPRY domain-containing SOCS box protein 1 * STIL (1p33) * SYCP1: Synaptonemal complex protein 1 * SZT2: Seizure threshold 2 homolog * TACSTD2: tumor-associated calcium signal transducer 2 * TAL1 (1p33) * TCTEX1D4: encoding protein Tctex1 domain containing 4 * TCEB3: Transcription elongation factor B polypeptide 3 * TGFBR3 (1p22) * THRAP3 (1p34) * TIE1 (1p34) * TMCO2: encoding protein transmembrane and coiled-coil domains 2 * TMCO4: encoding protein transmembrane and coiled-coil domains 4 * TMEM48: encoding protein nucleoporin NDC1 * TMEM50A: Transmembrane protein 50A * TMEM59: Transmembrane protein 59 * TMEM69: Transmembrane protein 69 * TMEM201 encoding protein Transmembrane protein 201 * TMEM222: Transmembrane protein 222 * TOE1: Target of EGR1 protein 1 * TRAPPC3: Trafficking protein particle complex subunit 3 * TRIT1: tRNA isopentenyltransferase, mitochondrial * TSHB: thyroid stimulating hormone, beta * TTC39A: Tetratricopeptide repeat 39A * UBR4: E3 ubiquitin-protein ligase component n-recognin 4 * UROD: uroporphyrinogen decarboxylase (the gene for porphyria cutanea tarda) * USP1 (1p31) * USP48: Ubiquitin carboxyl-terminal hydrolase 48 * VAV3 (1p13) * VPS13D: Vacuolar protein sorting-associated protein 13D * VTCN1 (1p13) * WARS2: Tryptophanyl-tRNA synthetase, mitochondrial * WDR77 (1p13) * YBX1 (1p34) * ZCCHC17: zinc finger CCHC-type containing 17 * ZMYM1 encoding protein Zinc finger MYM-type containing 1 * ZNF436: Zinc finger protein 436 * ZYG11B encoding protein Zyg-11 family member B, cell cycle regulator * ZZZ3: ZZ-type zinc finger-containing protein 3
### q-arm
인간 1번 염색체의 q-arm (long arm)에 있는 유전자의 일부 목록이다. * ABL2 (1q25) * ADIPOR1 (1q32) * AHCTF1: encoding protein ELYS * AKT3 (1q43-44) * ANGPTL1: Angiopoietin-related protein 1 * ARHGEF2 (1q22) * ARID4B: encoding protein AT-rich interactive domain-containing protein 4B * ARV1 encoding protein ARV1 homolog (S. cerevisiae) * ARNT (1q21) * ASPM (1q31): a brain size determinant * ATF3 (1q32) * ATP2B4 (1q32) * BCL9 (1q21) * CATSPERE: encoding protein Catsper channel auxiliary subunit epsilon * C1orf21: chromosome 1 open reading frame 21 * MMTAP2 encoding protein Multiple myeloma tumor-associated protein 2 * TEX35: TEX35 * C1orf74: chromosome 1 open reading frame 74 * C2CD4D: C2 calcium-dependent domain-containing 4D * CD5L: CD5 molecule like * CENPL: Centromere protein L * CENPF (1q41) * CHTOP: Chromatin target of prmt1 * CNIH4: cornichon homolog 4 * CNST: Consortin * CREG1: Cellular repressor of E1A stimulated genes 1 * CRP: C-reactive protein * CRTC2 (1q21) * CSRP1: Cysteine and glycine rich protein 1 * DCAF8: encoding protein DDB1 and CUL4 associated factor 8 * DDX59: DEAD-box helicase 59 * DEL1Q21: encoding protein Chromosome 1q21.1 deletion syndrome * DPT: Dermatopontin * DISC2, long non-coding RNA * DNAH14 encoding protein Dynein, axonemal, heavy chain 14 * DUSP10 (1q41) * DUSP27: encoding protein Dual specificity phosphatase 27 (putative) * ECM1 (1q21) * EDEM3: ER degradation enhancing alpha-mannosidase like protein 3 * EGLN1 (1q42) * ENAH (1q42) * ESRRG (1q41) * FAM163A: encoding protein neuroblastoma-derived secretory protein * FAM20B: FAM20B, glycosaminoglycan xylosylkinase * FAM63A: Family with sequence similarity 63, member A * FAM78B: family with sequence similarity 78, member B * FAM129A: family with sequence similarity 129, member A * FBXO28: F-box protein 28 * FCMR: Fc fragment of IgM receptor * FCGR2B (1q23) * FCGR2C: encoding protein Fc fragment of igg receptor iic (gene/pseudogene) * FH (1q43): fumarase * FMO3: flavin containing monooxygenase 3 * FRA1J encoding protein Fragile site, 5-azacytidine type, common, fra(1)(q12) * G0S2: encoding G0/G1 switch 2 * GAS5 (1q25) * GBA: glucosidase, beta; acid (includes glucosylceramidase) (gene for Gaucher disease) * GBAP1: glucosylceramidase beta pseudogene 1 * GLC1A: gene for glaucoma * GON4L: gon-4 like * GPA33 (1q24) * GPR37L1 G protein-coupled receptor 37 like 1 * HEATR1: HEAT repeat-containing protein 1 * HFE2: hemochromatosis type 2 (juvenile) * HIST2H2AB: Histone 2A type 2-B * HIST2H2BF: Histone H2B type 2-F * HIST2H3PS2: Histone cluster 2, H3, pseudogene 2 * HIST3H2A: Histone H2A type 3 * HIST3H2BB: Histone H2B type 3-B * HPC1: gene for prostate cancer * HRM2: Hair, curly * IGSF8 (1q23) * INAVA: Innate immunity activator protein * INTS3: Integrator complex subunit 3 * IRF6: gene for connective tissue formation * KCNH1 (1q32) * KIF14 (1q32) * LEFTY1: Left-right determination factor 1 * LHX9 encoding protein LIM homeobox 9 * LMNA: lamin A/C * LOC645166 encoding protein Lymphocyte-specific protein 1 pseudogene * LYPLAL1: Lysophospholipase-like 1 * MAPKAPK2 (1q32) * MIR194-1: microRNA 194-1 * MIR5008: microRNA 5008 * MPC2: Mitochondrial pyruvate carrier 2 * MOSC1: MOCO sulphurase C-terminal domain containing 1 * MOSC2: MOSC domain-containing protein 2, mitochondrial * MPZ: myelin protein zero (Charcot–Marie–Tooth neuropathy 1B) * MSTO1: misato 1 * MTR: 5-methyltetrahydrofolate-homocysteine methyltransferase * NAV1: Neuron navigator 1 * NBPF16: Neuroblastoma breakpoint family, member 16 * NOC2L: Nucleolar complex protein 2 homolog * NUCKS1: Nuclear ubiquitous casein and cyclin-dependent kinases substrate * NVL: Nuclear valosin-containing protein-like * OLFML2B: Olfactomedin-like 2B * OPTC: Opticin * OTUD7B: OTU domain-containing protein 7B * PACERR encoding protein PTGS2 antisense NFKB1 complex-mediated expression regulator RNA * PBX1 (1q23) * PEA15 (1q23) * PGDB5: PiggyBac transposable element derived 5 * PIAS3 (1q21) * PI4KB: Phosphatidylinositol 4-kinase beta * PIP5K1A (1q21): Phosphatidylinositol-4-phosphate 5-kinase type-1 alpha * PLA2G4A (1q31) * PPOX: protoporphyrinogen oxidase * PRCC (1q23) * PRR9 encoding protein Proline rich 9 * PSEN2 (1q42): presenilin 2 (Alzheimer disease 4) * PTGS2 (1q31) * PTPN14 (1q32-41) * PTPN7 (1q32) * RABIF: RAB interacting factor * RASSF5 (1q32) * RGS2 (1q31) * RN5S1@: RNA, 5S ribosomal 1q42 cluster * RPS27 (1q21) * SCAMP3: Secretory carrier-associated membrane protein 3 * SDHC (1q23) * SELE (1q24) * SHC1 (1q21) * SLC39A1 (1q21) * SLC50A1: Solute carrier family 50 member 1 * SMCP: Sperm mitochondrial-associated cysteine-rich protein * SMG7: nonsense mediated mRNA decay factor * SMYD3 (1q44) * SPG23 * SPRR1A: Cornifin-A * SPRR1B: Cornifin-B * SPRR2A: Small proline rich protein 2A * SPRTN: Spartan * TARBP1: TAR (HIV-1) RNA-binding protein 1 * TBCE: Tubulin-specific chaperone E * THBS3: Thrombospondin 3 * TMCO1: Transmembrane and coiled-coil domain-containing protein 1 * TMEM9: Transmembrane protein 9 * TMEM63A: Transmembrane protein 63A * TMEM81: Transmembrane protein 81 * TNFAIP8L2: encoding TNF alpha induced protein 8 like 2 * TNFSF18 (1q25) * TNN (1q25) * TNNT2: cardiac troponin T2 * TOR1AIP1: Torsin-1A-interacting protein 1 * TOR3A: encoding protein Torsin family 3 member A * TP53BP2 (1q41) * TRE-CTC1-5: Transfer RNA-Glu (CTC) 1-5 * TRP (1q31) * UAP1: UDP-N-acetylhexosamine pyrophosphorylase * USH2A: Usher syndrome 2A (autosomal recessive, mild) * USF1 (1q23) * VANGL2: encoding protein VANGL planar cell polarity protein 2 * VPS45: Vacuolar protein sorting-associated protein 45 * VPS72: Vacuolar protein sorting-associated protein 72 * YY1AP1: YY1-associated protein 1 * ZBED6: zinc finger, BED-type containing 6 * ZC3H11A: Zinc finger CCCH domain-containing protein 11A * ZNF648 encoding protein Zinc finger protein 648 * ZNF669: Zinc finger protein 669 * ZNF687: Zinc finger protein 687 * ZNF692: Zinc finger protein 692 * ZNF695: Zinc finger protein 695
# 질병 및 장애
이 염색체와 관련된 알려진 질병은 890가지이다. 이러한 질병 중 일부는 청각 장애, 알츠하이머병, 녹내장 및 유방암이다. 1번 염색체의 재배열 및 돌연변이는 암 및 기타 많은 질병에서 만연하다. 서열 변이의 패턴은 인간의 건강에 기여할 수 있는 특정 유전자의 최근 선택 신호와 기능이 명확하지 않은 영역을 나타낸다. 완전한 일염색체성(전체 염색체의 사본이 하나만 있음)은 출생 전에 항상 치명적이다.isbn=9781441916884 완전한 삼염색체(전체 염색체의 3개 사본 보유)는 수태 후 수일 이내에 치명적이다. 일부 부분 삭제 및 부분 복제는 선천적 장애를 생성한다. 다음 질병은 1번 염색체의 유전자와 관련된 질병 중 일부이다. (인간 염색체 중 가장 잘 알려진 유전성 질환 포함) colwidth=22em * 1q21.1 deletion syndrome * 1q21.1 duplication syndrome * Alzheimer's disease * Autosomal dominant Charcot-Marie-Tooth disease type 2 with giant axons * Breast cancer * Brooke Greenberg Disease (Syndrome X) * Carnitine palmitoyltransferase II deficiency * Charcot–Marie–Tooth disease, types 1 and 2 * collagenopathy, types II and XI * congenital hypothyroidism * Ehlers-Danlos syndrome * Factor V Leiden thrombophilia * Familial adenomatous polyposis * galactosemia * Gaucher disease * Gaucher-like disease * Gelatinous drop-like corneal dystrophy * Glaucoma * Hearing loss, autosomal recessive deafness 36 * Hemochromatosis * Hepatoerythropoietic porphyria * Homocystinuria * Hutchinson Gilford progeria syndrome * 3-hydroxy-3-methylglutaryl-CoA lyase deficiency * Hypertrophic cardiomyopathy, autosomal dominant mutations of TNNT2; hypertrophy usually mild; restrictive phenotype may be present; may carry high risk of sudden cardiac death * maple syrup urine disease * medium-chain acyl-coenzyme A dehydrogenase deficiency * Microcephaly * Muckle–Wells syndrome * Nonsyndromic deafness * Oligodendroglioma * Parkinson disease * Pheochromocytoma * porphyria * porphyria cutanea tarda * popliteal pterygium syndrome * prostate cancer * Stickler syndrome * TAR syndrome * trimethylaminuria * Usher syndrome * Usher syndrome type II * Van der Woude syndrome * Variegate porphyria div col end
# 세포유전학적 밴드
url=https://www.researchgate.net/publication/261304470 {| class="wikitable" |+G-bands of human chromosome 1 in resolution 850 bphs !Chr. !Arm !Band !ISCN

start !ISCN

stopThese values (ISCN start/stop) are based on the length of bands/ideograms from the ISCN book, An International System for Human Cytogenetic Nomenclature (2013). Arbitrary unit. !Basepair

start !Basepair

stop !Stain !Density |- |1 |p | |36.33 |0 |100 |1 |2300000 | |gneg | |- |1 |p | |36.32 |100 |244 |2300001 |5300000 | |gpos |25 |- |1 |p | |36.31 |244 |344 |5300001 |7100000 | |gneg | |- |1 |p | |36.23 |344 |459 |7100001 |9100000 | |gpos |25 |- |1 |p | |36.22 |459 |660 |9100001 |12500000 | |gneg | |- |1 |p | |36.21 |660 |861 |12500001 |15900000 | |gpos |50 |- |1 |p | |36.13 |861 |1206 |15900001 |20100000 | |gneg | |- |1 |p | |36.12 |1206 |1321 |20100001 |23600000 | |gpos |25 |- |1 |p | |36.11 |1321 |1521 |23600001 |27600000 | |gneg | |- |1 |p | |35.3 |1521 |1651 |27600001 |29900000 | |gpos |25 |- |1 |p | |35.2 |1651 |1780 |29900001 |32300000 | |gneg | |- |1 |p | |35.1 |1780 |1895 |32300001 |34300000 | |gpos |25 |- |1 |p | |34.3 |1895 |2210 |34300001 |39600000 | |gneg | |- |1 |p | |34.2 |2210 |2411 |39600001 |43700000 | |gpos |25 |- |1 |p | |34.1 |2411 |2770 |43700001 |46300000 | |gneg | |- |1 |p | |33 |2770 |2986 |46300001 |50200000 | |gpos |75 |- |1 |p | |32.3 |2986 |3273 |50200001 |55600000 | |gneg | |- |1 |p | |32.2 |3273 |3416 |55600001 |58500000 | |gpos |50 |- |1 |p | |32.1 |3416 |3732 |58500001 |60800000 | |gneg | |- |1 |p | |31.3 |3732 |3976 |60800001 |68500000 | |gpos |50 |- |1 |p | |31.2 |3976 |4206 |68500001 |69300000 | |gneg | |- |1 |p | |31.1 |4206 |4852 |69300001 |84400000 | |gpos |100 |- |1 |p | |22.3 |4852 |5210 |84400001 |87900000 | |gneg | |- |1 |p | |22.2 |5210 |5440 |87900001 |91500000 | |gpos |75 |- |1 |p | |22.1 |5440 |5741 |91500001 |94300000 | |gneg | |- |1 |p | |21.3 |5741 |5957 |94300001 |99300000 | |gpos |75 |- |1 |p | |21.2 |5957 |6029 |99300001 |101800000 | |gneg | |- |1 |p | |21.1 |6029 |6244 |101800001 |106700000 | |gpos |100 |- |1 |p | |13.3 |6244 |6459 |106700001 |111200000 | |gneg | |- |1 |p | |13.2 |6459 |6660 |111200001 |115500000 | |gpos |50 |- |1 |p | |13.1 |6660 |6861 |115500001 |117200000 | |gneg | |- |1 |p | |12 |6861 |7048 |117200001 |120400000 | |gpos |50 |- |1 |p | |11.2 |7048 |7119 |120400001 |121700000 | |gneg | |- |1 |p | |11.1 |7119 |7335 |121700001 |123400000 | |acen | |- |1 |q | |11 |7335 |7579 |123400001 |125100000 | |acen | |- |1 |q | |12 |7579 |8483 |125100001 |143200000 | |gvar | |- |1 |q | |21.1 |8483 |8756 |143200001 |147500000 | |gneg | |- |1 |q | |21.2 |8756 |8957 |147500001 |150600000 | |gpos |50 |- |1 |q | |21.3 |8957 |9244 |150600001 |155100000 | |gneg | |- |1 |q | |22 |9244 |9459 |155100001 |156600000 | |gpos |50 |- |1 |q | |23.1 |9459 |9832 |156600001 |159100000 | |gneg | |- |1 |q | |23.2 |9832 |10048 |159100001 |160500000 | |gpos |50 |- |1 |q | |23.3 |10048 |10349 |160500001 |165500000 | |gneg | |- |1 |q | |24.1 |10349 |10507 |165500001 |167200000 | |gpos |50 |- |1 |q | |24.2 |10507 |10679 |167200001 |170900000 | |gneg | |- |1 |q | |24.3 |10679 |10894 |170900001 |173000000 | |gpos |75 |- |1 |q | |25.1 |10894 |11009 |173000001 |176100000 | |gneg | |- |1 |q | |25.2 |11009 |11196 |176100001 |180300000 | |gpos |50 |- |1 |q | |25.3 |11196 |11598 |180300001 |185800000 | |gneg | |- |1 |q | |31.1 |11598 |11827 |185800001 |190800000 | |gpos |100 |- |1 |q | |31.2 |11827 |11942 |190800001 |193800000 | |gneg | |- |1 |q | |31.3 |11942 |12172 |193800001 |198700000 | |gpos |100 |- |1 |q | |32.1 |12172 |12617 |198700001 |207100000 | |gneg | |- |1 |q | |32.2 |12617 |12803 |207100001 |211300000 | |gpos |25 |- |1 |q | |32.3 |12803 |13033 |211300001 |214400000 | |gneg | |- |1 |q | |41 |13033 |13320 |214400001 |223900000 | |gpos |100 |- |1 |q | |42.11 |13320 |13406 |223900001 |224400000 | |gneg | |- |1 |q | |42.12 |13406 |13607 |224400001 |226800000 | |gpos |25 |- |1 |q | |42.13 |13607 |13966 |226800001 |230500000 | |gneg | |- |1 |q | |42.2 |13966 |14153 |230500001 |234600000 | |gpos |50 |- |1 |q | |42.3 |14153 |14397 |234600001 |236400000 | |gneg | |- |1 |q | |43 |14397 |14756 |236400001 |243500000 | |gpos |75 |- |1 |q | |44 |14756 |15100 |243500001 |248956422 | |gneg | |}