NLK-NML/MeSH-CZ-2025-notes huggingface dataset:
asialoglycophorin: glycophorin is a sialoglycoprotein
asialoorosomucoid: asialoorosomucoid is a 38-kda glycoprotein with a net negative charge of 5 carboxylic acid groups per molecule; asialo-alpha 1-acid glycoprotein is a serum asialoglycoprotein that has been measured as a potential indicator of hepatic disease
asialoorosomucoid-polylysine conjugate: soluble dna carrier system used to target a foreign gene specifically to liver in vivo via asialoglycoprotein receptors
asialoorosomucoid-polylysine-UMP conjugate: normal hepatocyte galactosamine-receptor targeted antagonist designed to protect normal cells from galactosamine toxicity
asiatic acid: from centella asiatica and other plants; shows a variety of bioactivities
asiaticoside B: cytotoxic cycloartane triterpene saponin from actaea asiatica
asimafoetidnol: from the gum resin of ferula assa-foetida
asimilobine: from nelumbro nucifera; rn given refers to (r)-isomer
asimilobine-2-O-glucoside: ; isolated from the tubers of stephania pierrei
asimin: an acetogenin; isolated from the stem bark of asimina triloba (annonaceae)
asiminacin: an acetogenin; isolated from the stem bark of asimina triloba (annonaceae)
asiminecin: an acetogenin; isolated from the stem bark of asimina triloba (annonaceae)
asiminocin: isolated from the stem of the paw paw tree, asimina triloba
asimitrin: antineoplastic annonaceous acetogenin from the seeds of asimina triloba possessing a bis-tetrahydrofuran ring
asitrocin: a mono-tetrahydrofuran acetogenin from asimina triloba seeds
aslavital: each vial contains procaine plus activating factor(possibly hematoporphyrin)
asmoganglina: combination of ephedrin, medullary suprarenal gland extract & posterior hypophysis extract
asnidin, Aspergillus nidulans: elastase inhibitor from aspergillus nidulans
asnovolin E: spiromeroterpenoid from the aspergillus novofumigatus; suppresses fibronectin expression
asolectin: highly purified phospholipid product containing lecithin, cephalin, inositol phosphatides & soybean oil; used to reconstitute acetylcholine receptor into liposomes; do not confuse with lectins
asp protein, Drosophila: binds to polar regions of mitotic spindle; isolated from drosophila melanogaster; amino acid
asp23 protein, Staphylococcus aureus: involved in alkaline ph tolerance in staphylococcus aureus; 169 amino acid residues, mw 23 kda; amino acid sequence given in first source
asp56-LDH(K): 56,000-dalton peptide; antigen in diverse cell lines transformed by the kirsten sarcoma & harvey sarcoma viruses; has ldh activity
aspA protein, Aeromonas salmonicida: amino acid sequence given in first source; genbank x67043
aspafilioside A: steroidal saponin from asparagus filicinus; used for treatment of bronchitis, pneumonitis & cough
aspafilioside B: steroidal saponin from asparagus filicinus; used for treatment of bronchitis, pneumonitis & cough
aspafilioside C: steroidal saponin from asparagus filicinus; used for treatment of bronchitis, pneumonitis & cough
aspaminol: was mh 1976-94 (see under piperidines 1976-90); use piperidines 1976-94; nonspecific spasmolytic with a mechanism of action different from that of papaverine
aspaoligonin A: cytotoxic steroidal saponin from the rhizomes of asparagus oligoclonos
aspaoligonin B: cytotoxic steroidal saponin from the rhizomes of asparagus oligoclonos
asparacosin A: c-27 spirosteroid from asparagus cochinchinensis
asparacosin B: spirostanol saponin from asparagus cochinchinensis
asparaginase erwinia chrysanthemi recombinant: to treat acute lymphoblastic leukemia and lymphoblastic lymphoma in patients who are allergic to e. coli-derived asparaginase products, as a component of a chemotherapy regimen
asparagine permease protein, Salmonella enterica: has high homology with the family of basic & aromatic amino acid permeases found in both prokaryotes & eukaryotes; 497 amino acids, mw 37-54 kda; from salmonella enterica; amino acid sequence given in first source; genbank u04851
asparagine-N-glycosyltransferase: involved in glycoprotein biosynthesis
asparagine-oxo-acid aminotransferase: consider also ec 2.6.1.45, serine-glyoxylate aminotransferase, which also acts on asparagine
asparaginyl endopeptidase, lysosomal: a cysteine protease which processes microbial antigens for class ii mhc presentation; also cleaves myelin basic protein
asparaginyl-alanyl-glycyl-alaninamide: synthetic tetrapeptide; has analgesic activity
asparaginyl-alanyl-glycyl-alanine: found in human brain; rn given refers to (l)-isomer
asparaginyl-alanyl-glycyl-alanyl-asparagine: synthetic pentapeptide; has analgesic acitivity
asparaginyl-glycyl-isoleucyl-tryptophyl-tyrosinamide: controls conncective tissue stiffness in sea cucumbers; amino acid
asparaginyl-isoleucyl-prolyl-norvalyl-leucyl-tyrosyl-seryl-phenylalanyl-alanyl-serinamide: a synthetic peptide with antifibrotic activity
asparaginyl-rhamnose: protein-carbohydrate linkage found in the crystalline surface layer of bacillus stearothermophilus, strain nrs 2004/3a
asparaginyl-seryl-phenylalanyl-arginyl-tyrosinamide: a pentapeptide fragment of anf; coordinates effectively to metals such as cu(ii)
asparaginyl-tRNA synthetase: genbbank aj222644 (arabidopsis); refseq nm_004539 (human)
asparaginyl-tryptophyl-phenylalaninamide: isolated from aplysia heart, involved in regulation of cardiac activity
asparagyl-alanyl-leucyl-phenylalanyl-glutamic acid: a bitter peptide
asparagyl-aspargyl-tryptophyl-asparagyl-asparagine: a quorum-sensing peptide for mazef-mediated cell death
asparagyl-valyl-valyl-arginyl-glutamine: a tumor-homing peptide
asparanin A: has antineoplastic activity; isolated from asparagus officinalis
asparaptine: angiotensin-converting enzyme inhibitor from asparagus officinalis
asparasone: a sclerotium-specific pigment of aspergillus flavus
asparenomycin: from streptomyces tokunonensis sp. nov.
aspartate N-acetyltransferase: nervous system enzyme that mediates synthesis of n-acetylaspartic acid; utilizes acetyl-coa
aspartate carbamoyltransferse regulatory polypeptide: mutation in gene encoding regulatory peptide caused biosynthesis of an aspartate carbamoyltransferase lacking substrate cooperative interactions
aspartate carboxypeptidase: aspartate carboxypeptidase, ec 3.4.17.5 is a deleted entry
aspartate dextran: non-penetrating succinate analog to study the molecular mechanism of outer membrane dicarboxylate transport in e coli; synthesized by coupling aspartate to dextran t-10
aspartic acid 2-oxoglutarate-dependent dioxygenase: hydroxylates one aspartic acid residue in the first egf-like unit of factor ix; bah humbug is a noncatalytic isoform
aspartic acid activating enzyme: requires atp, does not use trna, involved in bio-synthesis of peptidoglycan
aspartic acid-beta-4-nitroanilide: the sodium salt is suosan, a high potency sweetener derived from beta-alanine
aspartic protease inhibitor, Lupinus bogotensis: mw 12.84 kda inhibitor from seeds, effective against aspartic proteases from hypothenemus hampei
aspartic proteinase, Irpex lacteus: has been sequenced and crystallized; similar to several milk-clotting enzymes except that it is unstable at ph 6.0
aspartic proteinase-I: an extracellular proteinase from filamentous fungus, rhizopus niveus; amino acid sequence has been determined
aspartic proteinases, Cynara cardunculus: isolated from the cardoon cynara cardunculus; partial amino acid sequence given in first source
aspartoacylase: deficiency results in canavan disease; refseq nm_000049 (human)
aspartocin D: amphomycin analog from streptomyces canus strain fim-0916
aspartocin E: amphomycin analog from streptomyces canus strain fim-0916
aspartyl peptidase E: a serine hydrolase from salmonella; hydrolyzes asp-x peptides; inactive toward peptides with n-terminal asparagine or glutamic acid; see also entry for peptidase e
aspartyl phosphate phosphatase: removes phosphate groups from aspartic acid residues of proteins
aspartyl protease, Sclerotinia sclerotiorum: an unusual aspartyl protease expressed during phytopathogenesis; genbank af271387
aspartyl semialdehyde dehydrogenase, Helicobacter pylori: involved in the biosynthesis of lysine, isoleucine, methionine & threonine from aspartic acid
aspartyl-2,3-methanoproline propyl ester: ; rn given is for (1r-(1alpha,2(s*), 5alpha))-isomer
aspartyl-alanyl-diketopiperazine: generated by cleavage and cyclization from the n-terminus of human albumin during the preparation of commercial serum albumin product
aspartyl-alanyl-histidine-N-methylamide: tripeptide model for cu(ii)-transport site of serum albumin; rn given refers to (l)-isomer
aspartyl-arginyl-valyl-tyrosyl-isoleucyl-histidyl-prolyl-phenylalanyl-histidyl-leucyl-valyl-isoleucyl-histidine: a synthetic tridecapeptide corresponding to the n-terminal sequence of human angiotensinogen
aspartyl-aspartic acid: do not confuse with cyclo(asp-asp)
aspartyl-aspartyl-asparagyl-lysyl-isoleucine: binds copper(ii)
aspartyl-aspartyl-glutamyl-aspartic acid: antibodies to above peptide can inhibit transport of nuclear proteins into nucleus
aspartyl-aspartyl-seryl-aspartyl-glutamyl-glutamyl-asparagine: a synthetic peptide that modulates n-cam mrna and protein expression
aspartyl-glutamyl-glycyl-histidyl-lysyl-methionyl-leucyl-tyrosyl-phenylalaninamide: a cardioinhibitory peptide; produces dose-dependent decreases in both amplitude and rate of heart contractions
aspartyl-glutamyl-valyl-aspartal: a caspase inihibitor
aspartyl-glutamyl-valyl-aspartyl-aminoluciferin: a caspase 3/7 substrate and part of the caspase glo 3/7 assay system
aspartyl-glutamyl-valyl-aspartyl-p-nitroanilide: a chromogenic compound
aspartyl-glycyl-glutamyl-alanine: an oligopeptide releases ca(2+)
aspartyl-histidyl-glycyl-asparaginyl-methionyl-leucyl-tyrosyl-phenylalaninamide: a cardioinhibitory peptide; reduces only the amplitude of heart contractions
aspartyl-methionyl-prolyl-glycyl-threonyl-valyl-leucyl-proline: an mcf-7 cancer cell-binding peptide
aspartyl-phenylalanine: metabolite of aspartame; may inhibit angiotensin converting enzyme; rn given refers to all (l)-isomer
aspartyl-phenylalanyl-lysyl-leucyl-phenylalanyl-alanyl-valyl-tyrosyl-isoleucyl-lysyl-tyrosyl-arginine: has antiangiogenic activity; based on the amino-terminus of the gamma-chain of laminin-1
aspartyl-prolyl-glutaminyl-tyrosyl-isoleucyl-glutaminyl-seryl-arginine: synthetic laminin b1 chain octapeptide which posses laminin receptor binding ability
aspartyl-seryl-aspartyl-glycyl-lysine: a derivative of the ige-fc fragment (asp-ser-asp-pro-arg, positions 330-334)
aspartyl-tryptophyl-glutamyl-tyrosyl-seryl-valyl-tryptophyl-leucyl-seryl-asparagine: a dna-mimicking peptide
aspartyl-tyrosyl-arginyl-prolyl-leucyl-glutaminyl-phenylalaninamide: an nlp-12 neuropeptide
aspartyl-tyrosyl-phosphomethionyl-aspartyl-methionyl-lysine: amino acid sequence given in first source; corresponds to the alpha-pdgfr (platelet-derived growth factor receptor) binding site for p85 subunit of phosphatidylinositol 3-kinase binding subunit
aspartyllysine peptidase: from human intestinal brush border; stabilized by zn+2
asperaculin A: from a marine-derived fungus, aspergillus aculeatus
aspercetin: a platelet aggregating component from the venom of the snake bothrops asper which induces thrombocytopenia and potentiates metalloproteinase-induced hemorrhage; n-terminal amino acid
asperfuranone: an antineoplastic agent isolated from aspergillus nidulans
aspergchromone A: from the marine sponge-associated fungus aspergillus sp. scsio xws03f03
aspergchromone B: from the marine sponge-associated fungus aspergillus sp. scsio xws03f03
aspergentisyl A: isolated from the marine-derived fungus aspergillus glaucus hb1-19
aspergentisyl B: isolated from the marine-derived fungus aspergillus glaucus hb1-19
aspergicin: antibacterial isomers produced by co-culture of two mangrove epiphytic fungi
aspergilliamide B: from the deep-sea-derived fungus aspergillus westerdijkiae dffscs013
aspergillide A: cytotoxic 14-membered macrolide from marine-derived fungus aspergillus ostianus strain 01f313
aspergillide B: cytotoxic 14-membered macrolide from marine-derived fungus aspergillus ostianus strain 01f313
aspergillide C: 14-membered macrolide from marine-derived fungus aspergillus ostianus strain 01f313
aspergillin PZ: an isoindole alkaloid isolated from aspergillus awamori
aspergillitine: from the fungus aspergillus versicolor isolated from the marine sponge xestospongia exigua
aspergillopepsin I: included in group of microbial carboxyl proteinases, ec 3.4.23.6
aspergillopepsin II: nonpepsin-type acid proteinase; resistant to pepstatin
aspergillopeptidase Af: endopeptidase from aspergillus fumigatus
aspergillusene A: from the sea fan-derived fungus aspergillus sydowii psu-f154
aspergillusidone A: from the marine-derived fungus aspergillus unguis
aspergillusidone B: from the marine-derived fungus aspergillus unguis
aspergillusidone C: from the marine-derived fungus aspergillus unguis
aspergillusone A: from the sea fan-derived fungus aspergillus sydowii psu-f154
aspergilone A: has both antineoplastic and antifouling activities; isolated from aspergillus
aspergiodiquinone: isolated from the marine-derived fungus aspergillus glaucus hb1-19
aspergiolide A: an anti-tumor compound produced by marine-derived fungus aspergillus glaucus
aspergivone A: isolated from a gorgonian-derived aspergillus candidus fungus
aspergivone B: isolated from a gorgonian-derived aspergillus candidus fungus
asperidine b: isolated from the soil-derived fungus aspergillus sclerotiorum psu-rspg178
asperketal B: ; a diterpenoid isolated from the caribbean sea whip eunicea asperula
asperlicin: cholecystokinin antagonist; isolated from aspergillus alliaceus
asperlicin B: cholecystokinin antagonist; from aspergillus alliaceus; ; mf c31-h29-n5-o5
asperlicin C: cholecystokinin antagonist; from aspergillus alliaceus; ; mf c25-h18-n4-o2
asperlicin D: cholecystokinin antagonist; from aspergillus alliaceus; ; mf c25-h18-n4-o2
asperlicin E: cholecystokinin antagonist; from aspergillus alliaceus; ; mf c25-h18-n4-o3
asperlone A: inhibits protein tyrosine phosphatase b from mycobacterium tuberculosis; isolated from aspergillus
asperlone B: inhibits protein tyrosine phosphatase b from mycobacterium tuberculosis; isolated from aspergillus
aspernigrin C: has anti-hiv-1 activity; isolated from aspergillus niger
asperolide A: from the marine alga-derived endophytic fungus aspergillus wentii en-48
asperolide B: from the marine alga-derived endophytic fungus aspergillus wentii en-48
asperolide C: from the marine alga-derived endophytic fungus aspergillus wentii en-48
asperphenone A: phenone derivative extracted from mangrove-derived fungus aspergillus sp. yhz-1; has anti-bacterial activity
asperphenone B: phenone derivative extracted from mangrove-derived fungus aspergillus sp. yhz-1; has anti-bacterial activity
asperphenone C: phenone derivative extracted from mangrove-derived fungus aspergillus sp. yhz-1
asperterone: obtained from cultures of the endophytic fungus aspergillus terreus, isolated from the flowering plant mammea siamensis
asperterpenoid A: an inhibitor of mycobacterium tuberculosis protein tyrosine phosphatase b from the culture of aspergillus sp. 16-5c
asperterpenol A: isolated from a mangrove endophytic fungus aspergillus
asperterpenol B: isolated from a mangrove endophytic fungus aspergillus
asperterrestide A: from the marine-derived fungus aspergillus terreus scsgaf0162
aspertetranone D: from the marine algal-associated fungus aspergillus sp. zl0-1b14; has inhibitory effect against il-6 production
asperulosidic acid: from the fruit juice of morinda citrifolia (noni), a plant originally grown in the hawaiian and tahitian islands, has long been used by islanders to treat diseases, including cancer
asperversiamide A: cycloheptapeptide with activity against mycobacterium marinum
asperversiamide B: cycloheptapeptide with activity against mycobacterium marinum
asperversiamide C: cycloheptapeptide with activity against mycobacterium marinum
asperversin A: meroterpenoid with 5-6-6-6 ring structure isolated from marine fungus aspergillus versicolor
asperversin B: meroterpenoid with 5-6-6-6 ring structure isolated from marine fungus aspergillus versicolor
aspeverin: was isolated from the culture of an algicolous aspergillus versicolor
asphodelin A: antimicrobial aryl coumarin from asphodelus microcarpus
asphodelin A 4'-O-beta-D-glucoside: antimicrobial aryl coumarin glucoside from asphodelus microcarpus
asphorodin: a potent lipoxygenase inhibitory triterpene diglycoside from asphodelus tenuifolius
aspidin PB: has both anti-fibrotic and antineoplastic activities; isolated from dryopteris fragrans
aspidospermine: an indole fused to a qunoline; isolated from aspidosperma tree
aspidostomide E: antineoplastic bromopyrrole alkaloid from the patagonian bryozoan aspidostoma giganteum
aspinolide B: rn given for (2r-(2r*,3s*(e),4e,6r*,7s*))-isomer
aspirin, 4-hydroxybenzoic acid propyl ester, drug combination: consists of acetylsalicylic acid, p-hydroxybenzoic acid propyl ester & neutral filler
aspirin, aluminum hydroxide, magnesium hydroxide drug combination: aspirin mixed with aluminum & magnesium hydroxides
aspirin, butalbital and caffeine drug combination: combination drug of butalbital, caffeine and aspirin
aspirin, codeine, phenacetin, phenobarbital drug combination: combination of above cpds with caffeine
aspirin, dextropropoxyphene drug combination: combination of dextropropoxyphene & acetylsalicylic acid
aspirin, meprobamate drug combination: combination used for treatment of musculoskeletal pain &/or accompanied anxiety; used to treat muscle spasm-associated pain
aspirin, metoclopramide drug combination: combination of above cpds used in treatment of migraine
aspirin-phosphatidylcholine: attenuates low-dose aspirin-induced ulceration; in randomized clinical trial (11/2010)
aspoquinolone A: aspoquinolones a and d are stereoisomers; isolated from aspergillus nidulans
asprellic acid A: isolated from ilex asprella; asprellic acid a is the (3trans,27trans)-isomer; asprellic acid b is the (3trans,27cis)-isomer; asprellic acid c is the (3cis,27trans)-isomer (stereochemistry refers to the coumaroyl double bond)
aspririn, bamethan, escin drug combination: combination of aspirin, bamethan, & aescin used in treatment of thrombophlebitis
aspterpenacid A: from a mangrove endophytic fungus aspergillus terreus h010.
aspterpenacid B: from a mangrove endophytic fungus aspergillus terreus h010.
aspterric acid: rn given for (3r-(3alpha,4alpha,6aalpha,9aalpha))-isomer; isolated from aspergillus terreus
aspulvinone dimethylallyltransferase: catalyzes the transfer of the dimethylallyl moiety from dimethylallylpyrophosphate to either of the two aromatic rings of aspulvinone
asr protein, E coli: analysis of the asr dna sequence revealed an open reading frame coding for a 111-amino-acid polypeptide with a deduced molecular mass of approximately 11.6 kda; cloned in several species of bacteria; amino acid
assafoetidnol A: sesquiterpene coumarin from the roots of ferula assa-foetida
assafoetidnol B: sesquiterpene coumarin from the roots of ferula assa-foetida
assamicin I: inhibits free fatty acid release from and stimulates glucose uptake by rat adipocytes
assamicin II: inhibits free fatty acid release from and stimulates glucose uptake by rat adipocytes
assemblin: from herpes group viruses, including cytomegalovirus; involved in cleaving an assembly protein precursor which is encoded by the opposite half of the same open reading frame; amino acid sequence given in first source
assembly protein, Cytomegalovirus: mw 37 kda; capsid assembly protein of cytomegalovirus; nucleotide sequence given in first source
assembly protein, Human herpesvirus 8: aprotease and assembly protein; amino acid ; genbank af010430
ast protein, Drosophila: using cdna probes, asteroide transcripts were localized to the proliferative tissues of embryos and to the mitotically active tissue anterior to the morphogenetic furrow in eye imaginal discs; amino acid ; refseq nm_078727
astC protein, E coli: a succinylornithine transaminase involved in amino acid catabolism; isolated from e. coli; amino acid
astacin: a zinc-endopeptidase from the crayfish astacus astacus & hydra vulgaris; releases nitroaniline from succinyl-alanyl-alanyl-alanyl-4-nitroanilide (suc-ala-ala-ala-pna); acts on peptides containing 5 or more amino acids, preferably with ala in p1' and pro in p2'
astakine protein, Pacifastacus leniusculus: prokineticin-like cytokine from freshwater crayfish (pacifastacus leniusculus); induces a strong hematopoiesis response; genbank ay787656 (crayfish)
astakine protein, Penaeus monodon: prokineticin-like cytokine from shrimp (penaeus monodon); induces a strong hematopoiesis response; genbank ay787657 (shrimp)
astakolactin: sesterterpene metabolite from the mediterranean sponge cacospongia scalaris
astasilid: mixture of sucrose monoethers and semisaturated (3-6 double bonds) c20-c22 aliphatic cis-fatty acids; isolated from ciliated protozoan astasia longa
astasin: a cytotoxic carbohydrate-conjugated ergosterol; from the colorless euglenoid, astasia longa
astato-2-methyl-1,4-naphthoquinol diphosphate: rn given refers to parent cpd
astaxanthin-lysine conjugate Asly: a tetracationic astaxanthin-lysine conjugate
astaxanthin-s-allyl cysteine biconjugate: bioconjugate with antioxidant properties
astaxantin, calcium, citrus bioflavoid, lycopene, vitamin D3 drug combination: a combination of calcium, vitamin d3, lycopene, astaxantin, and citrus bioflavoid for reducing climacteric symptoms
asteltoxin: polyenic alpha-pyrone mycotoxin closely related to aurovertins isolated from aspergillus stellatus
asteltoxin C: from the entomopathogenic fungus pochonia bulbillosa 8-h-28
asteltoxin D: from the entomopathogenic fungus pochonia bulbillosa 8-h-28
astenose: produced by periodate oxidation of standard porcine mucosal heparin; has negligible anticoagulant activity
asteriaceramide A: phytosphingosine-type ceramide from the starfish asterias amurensis lütken with plant-growth promotion activities
asteriacerebroside G: glucocerebroside from the starfish asterias amurensis lütken with plant-growth promotion activities
asteriarubin protein, Asterias rubens: mw 43,000 tetramic carotenoprotein from starfish asterias rubens
asterina-330: mycosporine-like amino acid from gracilaria tenuistipitata
asteriscunolide A: from the aerial part of nauplius aquaticus (asteraceae)
asteriscunolide D: from the aerial part of nauplius aquaticus (asteraceae)
asterisulfone.: antibacterial and antifungal metabolite from the tunisian asteriscus maritimus (l.)
asterisulfoxide: antibacterial and antifungal metabolite from the tunisian asteriscus maritimus (l.)
asterobactin: a new siderophore group antibiotic from nocardia asteroides
asterogenol: from saponins of starfish asteriasis vulgaris; rn given for (3beta,5alpha,6alpha,20r)-isomer
asterolaurin A: from the taiwanese soft coral asterospicularia laurae; exhibited moderate cytotoxicity against hepg2 cells
asterolaurin D: from the taiwanese soft coral asterospicularia laurae; showed potent inhibition of elastase release and superoxide anion generation in vitro
asteropine A, Asteropus simplex: a sialidase-inhibiting conotoxin-like peptide from the marine sponge asteropus simplex; amino acid
asteropsin A: a cystine-crosslinked peptide from marine sponge asteropus sp. that enhances neuronal ca2+ influx; amino acid
asteropsin E: cystine knot peptide from asteropus sp, a marine sponge
asteropsin F: cystine knot peptide from the marine sponge asteropus sp
asteropsin G: cystine knot peptide from the marine sponge asteropus sp
asterric acid: ; inhibits the binding of endothelin-1 to the et(a) receptor of a10 cells
asterriquinol E: from aspergillus sp. cbs-p-2 with anti-inflammatory activity
asterriquinol F: from aspergillus sp. cbs-p-2 with anti-inflammatory activity
astilbin: dihydroflavonol from kohki tea processed from engelhardtia chrysolepis (huang-qui); astilbin is the (2r-trans)-isomer; neoisoastilbin is the (2s-cis)-isomer and is sweetening agents; isoastilbin is the (2r-cis)-isomer;
astragaloside A: isolated from astragalus membranaceus; rn given refers to astragaloside a (3beta,6alpha,16beta,24r)
astragaloside II: a potent multidrug resistance (mdr) reversal agent from astragalus
astragaloside VI: derived from radix astragali (ar) which is a commonly used medicinal herb for post-stroke disability in traditional chinese medicine
astramembranoside A: cycloartane saponin from the roots of astragalus membranaceus
astramembranoside B: cycloartane saponin from the roots of astragalus membranaceus
astrasieversianin XI: from astragalus sieversianus; protects liver from chemical injury induced by ccl4, galactosamine & acetaminophen
astrin: trichrome stain which contains alcian blue, safranine, thionine & resorcin
astrochondrin: a chondroitin sulfate proteoglycan from the murine central nervous system; expressed by astrocytes in vitro & carries the l2-hnk-1 & l5 carbohydrate structure; has been characterized
astrocytin: low mw protein fragments produced from in vitro brain glial tumors; bears specific tissue antigen & other immuno-chemical properties characteristic of the tumor
astropaquinone A: from the freshwater fungus, astrosphaeriella papuana
astropaquinone B: from the freshwater fungus, astrosphaeriella papuana
astropaquinone C: from the freshwater fungus, astrosphaeriella papuana
astrosclerin-3, Astrosclera willeyana: previously isolated from the sponge astrosclera willeyana; has a high catalytic activity for the co(2) hydration reaction to bicarbonate and protons
asulam: wild oat herbicide used in prairie regions for control of wild oats in cereal grains such as wheat; rn given refers to parent cpd
aszonapyrone A: produced by neosartorya fischeri fo-5897.
aszonapyrone B: produced by neosartorya fischeri fo-5897.
at3g18000 protein, Arabidopsis: amino acid ; refseq nm_112681.3
atHB-12 protein, Arabidopsis: arabiopsis thaliana gene product induced by water stress and abscisic acid treatment; 235 amino acids; amino acid ; genbank af001949
atalafoline: isolated from root of atalantia buxifolia (rutaceae)
ataluren: overrides nonsense stop translation signals to yield full-length proteins; may prove useful in treating cystic fibrosis and duchenne muscular dystrophy
atat1 protein, zebrafish: an alpha-tubulin acetyltransferase; refseq nm_213258
atelocollagen: used for artificial organs & tissue repair; has excellent properties as a carrier substance for the immobilization of various physiologically active substances
atemoyacin E: a bis-tetrahydrofuran annonaceous acetogenin from annona atemoya seeds (annonaceae)
atevirdine: inhibits replication of hiv-1; u 87201e is the methanesulfonate salt
atezolizumab: a monoclonal antibody that targets programmed death-ligand 1 (cd274 antigen) and is used to treat urothelial carcinoma, the most common type of bladder cancer
atf1 protein, S pombe: phosphoprotein with a bzip domain, which is required for proper g1 arrest and gene expression under nitrogen starvation; genbank d63666
atf21 protein, S pombe: closely related to human atf-2/cre-bp1; from schizosaccharomyces pombe; amino acid sequence given in first source
atg-16.1 protein, C elegans: refseq nm_076367.3
atg-16.2 protein, C elegans: refseq nm_062898.3
atg-4.2 protein, C elegans: refseq nm_069807.3
atg-9 protein, C elegans: atg - autophagy (yeast atg homolog); refseq nm_070777
atg11 protein, S pombe: autophagy protein; functions in cellular response to nitrogen starvation refseq nm_001019284
atherospermidine: isoquinoline alkaloid from artabotrys maingayi
atherospermine: a dimethyl-amino-phenanthrene deriv of nuciferine; alkaloid of atherosperma moschatum; rn given refers to parent cpd; do not confuse with spermine
athrolide C: antiplasmodial and antiproliferative from athroisma proteiforme from the madagascar dry forest
athrolide D: antiplasmodial and antiproliferative from athroisma proteiforme from the madagascar dry forest
athsr2 protein, Arabidopsis: a gene involved in early events conditioning the establishment of the hypersensitive response in arabidopsis thaliana; amino acid
atibuclimab: immunoglobulin g4, anti-(human cd14 antigen) (human-mus musculus monoclonal ic14 gamma4-chain), disulfide with human-mus musculus monoclonal ic14 kappa-chain, dimer
atkamine: alkaloid from the cold water aleutian islands latrunculia sponge
atm-1 protein, C elegans: refseq nm_001306285.1
atms protein, Drosophila: a paf1 complex protein that may be involved in modulating chromatin structure; refseq nm_141236
ato protein, Drosophila: expressed in the proneural clusters and sense organ precursors; directs chordotonal organ formation in the nervous system,
atomaric acid: from marine algae stypopodium zonale; with antiviral activity against hmpv
atovaquone, proguanil drug combination: comination of atovaquone and proguanil hydrochloride
atp1a1a.1 protein, zebrafish: refseq nm_131686
atp6ap1.1 protein, Xenopus: part of the membrane sector of h(+) atpase; mw 50 kda;
atpB protein, E coli: an f(0) component protein of f(1)f(0)atpase
atpD protein, E coli: h+-transporting two-sector atpase; papb proteinisolated from e. coli, has a dual function as an activator or repressor of pilus-adhession transcription; has been sequenced
atpE protein, E coli: amino acid sequence known; an f(0) component protein of f(1)f(0)atpase
atpG protein, E coli: involved in pilus biogenesis across the outer membrane; amino acid sequence known
atpH protein, Pavlova lutherii: amino acid sequence given in first source; a homolog of chloroplast-encloded secy gene; from unicellular chromophytic alga, pavlova lutherii
atpenin A4: from penicillium sp. fo-125; mw c15-h22-n-o5-cl
atpenin A5: from penicillium sp. fo-125; mw c15-h21-n-o5-cl2
atpenin B: from penicillium sp. fo-125; mw c15-h23-n-o5
atpk1 protein, Arabidopsis: a ribosomal protein kinase expressed in all tissues & involved in the control of plant growth & development; from arabidopsis thaliana; amino acid sequence given in first source; genbank l29030
atracotoxin-Hi-OB4219: a 38-residue toxin from the venom of hadronyche infensa sp. that contains a cystine-knot motif within its four disulfide bonds
atractylodin: rn given for (e,e)-isomer; isolated from atractylodes plants
atractylon: from atractylodes rhizomes; has antihepatotoxic activity
atramine: ant-cholinesterase factor isolated from venom of naja naja atra; mw approx 50,000; isoelectic point 6.8; do not use /antag
atratoxin-b: a short-chain alpha-neurotoxin purified from naja atra (mainland chinese cobra) venom
atratumycin: ten amino acid residues cyclodepsipeptide with activity against mycobacterium tuberculosis isolated from deep-sea derived streptomyces atratus scsio zh16ns-80s
atraxin: protein isolated from venom glands of male and female funnel-web spiders
atrazine chlorohydrolase: an atrazine-dechlorinating enzyme with restricted substrate specificity & contributes to the microbial hydrolysis of atrazine to hydroxyatrazine in soils & groundwater
atrial dipeptidyl carboxyhydrolase: removes c-terminal phe-arg from atriopeptin ii to give atriopeptin i; metalloenzyme with mw 240,000; also has tripeptidyl carboxyhydrolase activity; removes phe-arg-tyr from atriopeptin iii to form atriopeptin i
atrial granule serine proteinase: converts pro-atrial natriuretic factor to anf by cleaving the arg98-ser99 bond; n-terminal 26-residue amino acid sequence given in first source
atrial natriuretic factor (1-27): amino acid sequence given in first source; a major circulating form of anp found in eel plasma
atrial natriuretic factor (101-105): product of endopeptidase-24.11 action on rat anf(101-126)
atrial natriuretic factor (106-126): product of endopeptidase-24.11 cleavage of rat anf(101-126)
atrial natriuretic factor (3-28): corresponds to rat des-1,2-alpha-anf with isoleucine in position 12; contains 26 amino acid residues
atrial natriuretic factor (4-23): a c-type natriuretic peptide fragment
atrial natriuretic factor 26, rat: peptide corresponding to the 26 residues of the c-terminal of rat atrial natriuretic factor
atrial natriuretic factor 270: amino acid sequence given in first source; a 26 amino acid analog of naturally occuring alpha-h-anf; has potential for treatment of congestive heart failure and acute renal failure
atrial natriuretic factor prohormone (1-30), human: the 30-amino acid fragment at the n-terminal of the human anf prohormone, atrial natriuretic factor (1-126); a long-acting natriuretic peptide (lanp); found in humans; do not confuse with lanp protein
atrial natriuretic factor prohormone (1-98): the 98-amino acid fragment at the n-terminal of the anp prohormone, atrial natriuretic factor (1-126); its circulating level is related to heart diseases
atrial natriuretic factor prohormone (102-125): a 24-amino acid atrial natriuretic factor corresponding to the (102-125) sequence of atrial natriuretic factor prohormone
atrial natriuretic factor prohormone (103-123): from mammalian atria; contains 21-amino acid residues corresponding to the c-terminal fragment (103-123 residues) of atrial natriuretic factor prohormone or (127-147 residues) of the anf precursors; relaxes intestinal but not vascular smooth muscle strips, and is natriuretic
atrial natriuretic factor prohormone (103-125): from mammalian atria; contains 23-amino acid residues corresponding to the c-terminal fragment (103-125 residues) of atrial natriuretic factor prohormone or (127-149 residues) of the anf precursors; relaxes intestinal and vascular smooth muscle strips and is a potent natriuretic; amino acid sequence given in first source
atrial natriuretic factor prohormone (103-126): from mammalian atria; contains 24-amino acid residues corresponding to sequence (103-126) of the anf prohormone atrial natriuretic factor (1-126), or sequence (127-150) of the anf precursors; relaxes intestinal and vascular smooth muscle strips and is a potent natriuretic; amino acid sequence given in first source
atrial natriuretic factor prohormone (31-67): found in humans; a 37-amino acid peptide derived from (31-67 residues) of anp prohormone (1-126 residues)
atrial natriuretic factor prohormone (49-126): a 78-amino acid peptide, derived from the (49-126 residues) of anp prohormone (1-126 residues)
atrial natriuretic factor prohormone (6-33), rat: a 28-amino acid atrial natriuretic factor corresponding to the (6-33) sequence of atrial natriuretic factor prohormone
atrial natriuretic factor receptor A: a member of the npr/guanylyl cyclase family
atrial natriuretic factor receptor C: a clearance receptor for atrial natriuretic factor, not linfed to guanylate cyclase
atrial natriuretic peptide (101-126), Ile(12)-: do not confuse with ileu-anp which corresponds to human anp(8-33) with substitution of isoleucine for methionine at position 17
atrial natriuretic peptide, rat: rat natriuretic peptide precursor type a, ref seq nm_012612; see also non-organism-specific peptides, natriutretic peptides
atrioactivase: selectively cleaves the arg(98)-ser(99) peptide bond in pro-atrial natriuretic factor during or just after the process of secretion from the heart atrium
atriplexoside A: extract of the aerial parts of egyptian atriplex halimus l.
atriplexoside B: extract of the aerial parts of egyptian atriplex halimus l.
atrolactic acid: see also 3-isomer; rn given refers to parent cpd without isomeric designation
atrolysin C: ht-c and ht-d differ by one amino acid; see also atrolysin a (ec 3.4.24.1)
atrolysin F: from venom of crotalus atrox (western diamondback rattlesnake); mw 64,000 with 572 amino acid residues; contains 1 mol zinc/mol protein; has both proteolytic & hemorrhagic acitvities
atromentin: an enoyl-acp reductase (fabk) inhibitor; isolated from streptococcus pneumoniae
atrop-O-benzyl-desmethylabyssomicin C: has antibacterial activity
atrophin 2, mouse: recruits histone deacetylase and is required for the function of multiple signaling centers during mouse embryogenesis; refseq np_039268
atrophin-1: drpla with cag glutamine repeat expansion leads to dentatorubral-pallidoluysian atrophy (drpla)
atropine dehydrase: proposed mechanism for conversion of atropine or scopolamine to apoatropine or aposcopolamine via a mechanism using hydroxysteroid sulfotransferase by guinea pig liver
atropine sulfate-diphenoxylate hydrochloride drug combination: contains diphenoxylate & atropine sulfate; see also record for lyspafen whcih contains difenoxine & atropine sulfate
atropine, dipyridamole, ifenprodil tartrate, papaverine, piribedil, yohimbine drug combination: mixture of papaverine & 5 vasoactive substances (alpha-1 & alpha-2 blockers, dopaminergic, anticholinergic & a phosphodiesterase inhibitor); the mixture cotains papaverine hcl, ifenprodil tartrate, atropine sulfate, yohimbine, dipyridamole & piribedil
atropine, pralidoxime iodide, trichlorofon drug combination: contains trichlorophon, pyridinaldoxime methyl iodide, and atropine sulfate
atroside: an acylated steroid glucoside, has been isolated from perovskia atriplicifolia
atroviolacin A: from swertia atroviolacea with anti-5α-reductase activity
atroviolacin B: from swertia atroviolacea with anti-5α-reductase activity
atrovirinone: from the roots of garcinia atroviridis (guttiferae)
atrovirisidone: from the roots of garcinia atroviridis (guttiferae)
atroxase: nonhemorrhagic fibrinolytic protease from western diamondback rattlesnake (crotalus atrox) venom: an aalpha, bbeta fibrinogenase, cleaves alpha chain of fibrinogen first followed by beta chain and shows no effect on gamma chain; consists of a single nonglycosylated polypeptide chain; mw: 23,500; amino acid sequence given in second source; genbank s77086; does not inhibit platelet aggregation
atroxin: serine protease purified from bothrops atrox venom; cleaves fibrinopeptide a from fibrinogen; available from sigma
atsizol: a russian drug; a zinc-containing imidazole derivative; no other info avail 3/94
att-ORFB protein, Drosophila: att encodes alternative mrnas and proteins homologous to those of mammalian graves' disease carrier proteins; isolated from testis and somatic tissues of drosophila melanogaster; amino acid ; refseq nm_206523
attachment protein G: an envelope glycoprotein from members of the pneumovirus genus as well as from hendra virus; it is responsible for binding the virus to specific receptor molecules on the host cell surface and is similar to hn protein; genbank af017149
attacin antibacterial protein, insect: antibacterial proteins from insects; antibacterial activity against e coli & other gram-negative bacteria; a-d are basic, e & f are acidic; amino-terminal ; see also related cecropin a,b,d
attapulgite: accelerates oxidative degradation of hydrocortisone; rn given refers to cpd with unknown mf
attapulgite, bismuth subcarbonate, kanamycin, drug combination: used in treatment of bacterial enteritis in dogs
attenol A: from chinese bivalve pinna attenuata; a & b are enantiomers & exhibit cytotoxicity against p388 cells
attenuin: putative nonsteroidal ovarian factor that attenuates the luteinizing hormone (lh) surge in superovulated women; attenuates rather than completely inhibit lh surge; has not been convincingly characterized and no published candidate amino acid sequences available
attractin protein, Aplysia: a water-borne peptide pheromone in invertebrates; from aplysia; amino acid ; separate record for vertebrate attractin
auR protein, Staphylococcus aureus: included in the group of microbial metalloproteinases ec 3.4.24.4; ptrb protein is isolated from e coli; sakstar is recombinant staphylokinase; genbank d10976 (e coli)
aub protein, Drosophila: encodes a drosophila polar granule component required for pole cell formation and related to eif2c; amino acid ; refseq nm_057386
aucuparin: biphenyl phytoalexin in sorbus aucuparia cell cultures
augustineolide: limonoid from swietenia species (meliaceae); antifeedant activity;
auracyanin A protein, bacteria: blue copper protein from the green photosynthetic bacterium chloroflexus aurantiacus; amino acid sequence given in first source
auracyanin B-1 protein, bacteria: blue copper protein from the green photosynthetic bacterium chloroflexus aurantiacus; amino acid sequence given in first source
auracyanin B-2 protein, bacteria: blue copper protein from the green photosynthetic bacterium chloroflexus aurantiacus; amino acid sequence given in first source
auranthine: identified in extracts of mycelia of most of the nephrotoxic fungi cultured on cdye both
aurantiamide benzoate: isolated from cunila spicata and hyptis fasciculata, two tropical medicinal plants
aurantin: a mixture of actinomycines; was heading 1973-95 (prov 1965-72); use aurantin (nm) to search aurantin 1966-95
aurantio-obtusin: main anthraquinone in "jue-ming-zi", therapeutic for hyperlipidemia
aurantiomide A: quinazoline alkaloid from the sponge-derived fungus penicillium aurantiogriseum sp0-19
aurantiomide B: quinazoline alkaloid from the sponge-derived fungus penicillium aurantiogriseum sp0-19
aurantiomide C: quinazoline alkaloid from the sponge-derived fungus penicillium aurantiogriseum sp0-19
aurantoside G: tetramic acid glycoside from a papua new guinea theonella swinhoei
aurantoside H: tetramic acid glycoside from a papua new guinea theonella swinhoei
aurantoside I: tetramic acid glycoside from a papua new guinea theonella swinhoei
aurantoside K: an antifungal tetramic acid glycoside from a fijian marine sponge of the genus melophlus
aurasperone B: has free radical scavenging activity; isolated from aspergillus niger
aurasperone F: a member of the naphtho-gamma-pyrone class isolated from a cultured microfungus, aspergillus niger c-433
aurasperone H: antineoplastic from marine-derived fungus aspergillus niger 2hl-m-8
aurechinulin: alkaloid from mycelium of aspergillus amsterodami
aurein 1.2 peptide: antomicrobial chemically related peptide from australian tree frogs; has been sequenced
aureobasidin A: inositol phosphorylceramide synthase inhibitor; ; isolated from the culture medium of aureobasidium pullulans r 106
aureobasidin S1: produced by aureobasidium pullulans r106; cyclic depsipeptide composed of eight amino acids & one hydroxy acid
aureobasidin S2a: produced by aureobasidium pullulans r106; cyclic depsipeptide composed of eight amino acids & one hydroxy acid
aureobasidin S2b: produced by aureobasidium pullulans r106; cyclic depsipeptide composed of eight amino acids & one hydroxy acid
aureobasidin S3: produced by aureobasidium pullulans r106; cyclic depsipeptide composed of eight amino acids & one hydroxy acid
aureobasidin S4: produced by aureobasidium pullulans r106; cyclic depsipeptide composed of eight amino acids & one hydroxy acid
aureocin A70: a multi-peptide bacteriocin isolated from staphylococcus aureus; genbank af241888
aureolysin: member of the thermolysin family of zinc-dependent metalloproteinases; isolated from staphylococcus aureus; amino acid
aureonitol B: isolated from the solid fermentation culture of the plant endophytic fungus chaetomium globosum from the aerial parts of salvia miltiorrhiza
aureoverticillactam: a macrocyclic lactam from streptomyces sp.
aureusidin synthase: catalyzes the hydroxylation and/or cyclization of both 2',4',6',4-tetrahydroxychalcone and 2',4',6',3,4-pentahydroxychalcone; involved in flower coloration
auricularum: combination of above three antibiotics and dexamethasone 21-phosphate; used in the treatment of chronic middle ear disease
aurilide: a 26-membered cyclodepsipeptide from the japanese sea hare dolabella auricularia
aurilide A: from the marine cyanobacterium lyngbya majuscula collected from papua new guinea; structue in first source
aurilide B: from the marine cyanobacterium lyngbya majuscula collected from papua new guinea; structue in first source
aurilide C: from the marine cyanobacterium lyngbya majuscula collected from papua new guinea; structue in first source
aurocitrin: from the wood-decay fungus hypocrea sp. bcc 14122
auromomycin: c35h33no12; macromomycin is the apoprotein of auromomycin which is the cytotoxic chromophore
auromycin: degrades dna in a manner which is sensitive to the sequence of dna bases
aurovertin F: from the fermentation broth of entomopathogenic fungus metarhizium anisopliae
aurovertin G: from the fermentation broth of entomopathogenic fungus metarhizium anisopliae
aurovertin H: from the fermentation broth of entomopathogenic fungus metarhizium anisopliae
aust protein, Drosophila: a chromosomal passenger complex subunit required for male meiosis; refseq nm_135434
austin: toxic metabolite of aspergillus ustus found on stored black-eyed peas
austocystin D: a potent and selectively cytotoxic compound from aspergillus isolate ugm218
austradixanthone: from the fungal endophyte aspergillus austroafricanus
australifungin: contains a combination of alpha-diketone and beta-ketoaldehyde groups; from sporormiella australis; inhibits sphinganine n-acyltransferase (ceramide synthetase)
australine: rn & ; inhibits amyloglucosidase & glycoprotein processing
austrobailignan 1: rn given for (5r-(5alpha,5abeta,8aalpha))-isomer
austrobailignan 2: rn given for (5r-(5alpha,5aalpha,8aalpha))-isomer
austrobrasilol A: from hypericum austrobrasiliense exhibiting antinociceptive activity
austrocortilutein: formed in the fruit bodies of the fungus dermocybe splendida
austrocortirubin: formed in the fruit bodies of the fungus dermocybe splendida
autoantigen 1, Cavia porcellus: a guinea pig sperm acrosome protein; member of the cysteine-rich secretory protein (crisp) family; genbank u35712
autocamptide-2-related inhibitory peptide II: a calmodulin-dependent protein kinase ii inhibitor
autocamtide-2: 13 amino acid residue substrate of ca(2+)-calmodulin-dependent protein kinase ii
autocide AMI: from myxococcus xanthus; induces lysis in cultures of myxococcus xanthus & closely related strains
autocrine growth factor, hepatoma cells: apparent mw 60,000; specifically stimulates dna synthesis & cell proliferation of htc cells
autophosphorylation-dependent multifunctional protein kinase: a camp/ca(2+)-independent protein kinase; phosphorylates and activates phosphorylase b kinase; phosphorylates and inactivates glycogen synthase
autorosette inhibition factor, mouse: inhibits the ability of murine lymphocytes to bind to autologous erythrocytes; glycoprotein mw 80,000
autosomal recessive hypercholesterolemia protein, Xenopus: required for vitellogenesis; amino acid
autotransporter-adhesin-heptosyltransferase, E coli: a heptosyltransferase involved in maturation of aida-i adhesin in e. coli; amino acid
autoxidized methyl linoleate: formed from autoxidation of methyl linoleate at 40 or 60 degrees c by passing oxygen through it
autumnalamide: from the cyanobacterium phormidium autumnale; acts on sh-sy5y cells at the mitochondrial level
auxarconjugatin A: from an australian isolate of the soil ascomycete gymnoascus reessii
auxin regulated proteins, Vigna radiata: from mung bean, vigna radiata; arg2 is 39% identical to lea5-a protein from cotton; arg1 is 69% identical to delta(15) fatty-acid desaturase; amino acid sequence given in first source amino acid sequence given in first source
auxin response factor 8, Arabidopsis: disruption and overexpression of auxin response factor 8 gene of arabidopsis affect hypocotyl elongation and root growth habit, indicating its possible involvement in auxin homeostasis in light condition; refseq mrna nm_123060; protein np_198518
auxin-binding protein 1: from many plants; contains (-)-charged aa around the n-terminus and a c-terminal kdel motif which retains proteins within the lumen of the er; aa sequence given in first source; genbank s40550
auxin-responsive protein IAA7, Arabidopsis: refseq nm_113205
avapyran: protein tyrosine phosphatase 1b inhibitor from dysidea sp., a marine sponge collected in okinawa
avarol: rn given refers to parent cpd; extract from dysidea avara(sea sponge)
avarol monoacetate: ; cytotoxic and antitumor activity twice that of avarol
avathrin, Amblyomma variegatum: thrombin inhibitor from salivary glands of the ixodid tick
avd protein, zebrafish: a biotin-binding protein expressed in male and female gonads; similar to avidin in structure; refseq nm_001201442
avellanin A: from hamigera avellanea stolk et samson; increases blood pressure
avellanin B: from hamigera avellanea stolk et samson; increases blood pressure
avelumab: targets programmed cell death protein-1 ligand; has antineoplastic activity
avenacin A 1: an oat root saponin; rn refers to (3beta,4alpha,12beta,16beta,20beta,21beta)-isomer
avenacinase protein, Gaeumannomyces graminis: a 110 kda saponin-detoxifying enzyme from fungus, gaeumannomyces graminis; removes both the beta-1,2- & beta-1,4-linked terminal d-glucose molecules from oat root saponin a-1 to give first the mono- and then the bis-deglucosylated form, both are less toxic to the fungus; genbank u17568