NLK-NML/MeSH-CZ-2025-notes huggingface dataset:
salinixanthin: from salinibacter ruber, an extremely halophilic eubacterium
salinomycin: from streptomyces albus; rn given refers to parent cpd
salinosporamide B: from the marine actinomycete salinispora tropica
salinosporamide C: from the marine actinomycete salinispora tropica
salinosporamide K: inhibits 20s proteasome; isolated from salinispora pacifica
salithion: causes irreversible ataxia in chicken, mice & sheep; structure in pesticide index, 5th ed, p.202
saliva-binding protein, Streptococcus sanguis 12: mw 36 kda; may play a role in oral colonization by binding either to a receptor on saliva or on actinomyces; amino acid sequence given in first source
saliva-interacting cell wall protein, Streptococcus: mw 74,000; recognized by monoclonal antibody lo sm2; purified by monoclonal-antibody immunoaffinity chromatography
salivaricin CRL 1328: a two-peptide bacteriocin produced by lactobacillus salivarius crl 1328 isolated from the human vagina
salivary adhesion-promoting protein, human: a high molecular-weight (250,000-300,000 da) adhesion-promoting protein
salivary agglutinin receptor, Streptocococcus: amino acid sequence given in first source; from streptocococcus mutants kpsk2 & streptococcus sanguis m5; enables bacteria to bind to agglutinin to facilitate colonization of mouth
salivary gland protein 29 kDa, Haemaphysalis longicornis: a haemaphysalis longicornis tick salivary gland-associated cdna coding for a 29-kda extracellular matrix-like protein; a vaccine against tick infestation in rabbits; amino acid
salivary lipocalin protein, Sus scrofa: binds steroidal sex pheromones; isolated from boar saliva; genbank aj249974
salivary peptide P-C: a proline-rich peptide comprised of 44 amino acids
salivary plasminogen activator alpha 1, Desmodus rotundus: displays strict fibrin specificity; cleared fourfold slower from circulation than t-pa
salivary protein 14, Ixodes scapularis: anticoagulant salivary protein in adult ixodes scapularis involved in tick feeding and engorgement; different mechanisms govern nymph and adult feeding; has been sequenced
salivary protein fragment IB7(14), human: the secondary structure of ib7(14) is made of a type ii helix (collagen helix) and random coil; the central glycine 8 appears to act as a flexible rotula separating two helix ii regions; amino acid sequence is sppgkpqgpppqgg
salmahyrtisol A: from the red sea sponge hyrtios erecta
salmefamol: beta adrenergic stimulant similar to albuterol; used as a bronchodilator with little effect on the cardiovascular system; minor descriptor (77-86); on-line & index medicus search ethanolamines (77-86); rn given refers to parent cpd
salmolysin: transcription regulator that either activates or represses expression of target genes; may be required for virulence and survival in the macrophage environment
salmon gonadotropin-releasing hormone precursor: amino acid sequence given in first source; genbank d26108
salmon growth hormone type II: amino acid sequence given in first source; 210 amino acid residues; from chum salmon (oncorhynchus keta)
salmorin: isolated from agkistrodon halys brevicaudus; amino acid ; genbank af125309 and af125310
salmosin: from agkistrodon halys brevicaudus venom; amino acid
salmozan: polysaccharide isolated from the somatic o-antigen of salmonella
salolase: hydrolyzes phenyl esters (salicylates); may be classified with a-esterase, ec 3.1.1.2
salsoline: monomethylated metabolite of salsolinol; endogenous neurotoxin found in csf of patients with parkinson's disease
salsolinol: rn given refers to cpd without isomeric designation; ep to salsoline alkaloids (78-82); on-line search salsoline alkaloids (78-82); index medicus search isoquinolines (78-82)
salsolinol synthase, rat: uncharacterized. no refseq or rgd info available
salt-tolerant glutaminase: is a salt-tolerant protein which shows equivalent activities both in the absence and the presence of 3 m sodium chloride and is distinct from halophilic proteins
salternamide A: from a halophilic streptomyces sp. actinobacterium
salusin-beta, rat: salusin-beta may be involved in the regulation of body fluid balance by stimulating neurohypophyseal hormone release from nerve endings by an autocrine/paracrine mechanism
salutaridine: isolated from nandina domestica thunb; rn given refers to parent cpd
salutaridine reductase, Papaver: reaction: salutaridinol + nadp+ = salutaridine + nadph + h+; catalyses the reversible reduction of salutaridine to salutaridinol, which is a direct precursor of morphinan alkaloids in the poppy plant; genbank ef184229
salvianolate: from radix salviae miltiorrhizae that could improve impaired microvascular reflow induced by ischaemia/reperfusion injury
salvicin: a biocyclic diterpenoid; ensures the preservation of islet beta-cells in animals with alloxan diabetes
salvidorol: nor-abietane diterpene with a rare carbon skeleton from salvia dorrii
salvimultine: a noricetexane diterpene from the roots of salvia multicaulis
salvin: a biocyclic diterpenoid; from sage and rosemary (lamiaceae)
salvinicin A: neoclerodane diterpene from salvia divinorum (lamiaceae)
salvinicin B: neoclerodane diterpene from salvia divinorum (lamiaceae)
salviniol: has antineoplastic activity; isolated from giant salvinia, salvinia molesta
salvinorin D: neoclerodane diterpenoid from the leaves of salvia divinorum
salvinorin E: neoclerodane diterpenoid from the leaves of salvia divinorum
salvinorin F: neoclerodane diterpenoid from the leaves of salvia divinorum
salvipisone: diterpenoid with antimicrobial activity from hairy roots of salvia sclarea l.
salvisertin A: a hexacyclic triterpenoid isolated from salvia deserta root
samaderin A: from seeds & bark of samadera indica (simaroubaceae)
samaderin B: from seeds & bark of samadera indica (simaroubaceae)
samaderin C: from seeds & bark of samadera indica (simaroubaceae)
samarangenin B: an antiviral agent and chinese herbal drug isolated from limonium sinense
samarcandin: from oleo-gum resin of ferula assa-foetida l
samatasvir: an antiviral agent that inhibits ns5a protein from hepatitis c virus
samboginone: isolated from the leaves of the philippine medicinal herb sambong, blumea balsamifera
sambulin: isolated from sambucus ebulus; sambulin a and b have anti-inflammatory activity towards macrophages in vitro
sambunigrin: from leaves of the edible passion fruit plant, passiflora edulis
samchuleum: traditional korean herbal preparation composed of rehmannia glutinosa, paeonia lactiflora, cnidium officinale makino, angelica sinensis, panax japonicus, atractylodes ovata, pinellia ternata, citrus reticulata and glycyrrhiza glabra; it is used to treat dysuria in pregnant women and renal dysfunction
samgiumgagambang: an extract of 14 herbs, rehmannia glutinosa (rehmanniae radix preparata), eucommia ulmoides (eucommiae cortex), achyranthes japonica (achyranthis radix), lycium chinese (lycii fructus), poria cocos (hoelen alba), paeonia lactiflora (paeoniae radix), aconitum carmichaeli (aconiti tuber), aralia continentalis (araliae continentalis radix), glycyrrhiza uralensis (glycyrrhizae radix), cinnamomum cassia (cinnamoni ramulus), angelica gigas (angelicae radix), coptis japonica (coptidis rhizoma), phyllostachys nigra (bambusae caulis in taeniam), and zingiber officinale (zingiberis rhizoma)
samioside: from phlomis samia (lamiaceacea, labiatae)
samital: for treatment of chemotherapy-induced gastrointestinal mucositis; prepared from vaccinium myrtillus, macleaya cordata, and echinacea angustifolia
sampangine: a plant-derived copyrine alkaloid extracted from the stem bark of cananga odorata
samui protein, Bombyx mori: a cold-inducible protein isolated from bombyx (silkworm) diapause eggs; genbank ab032717
samultang: radix rehmammiae, radix angelicae gigantis, radix paeoniae, and rhizoma cnidii misture extract
san ch'i: hemostatic from herb roots; well-known drug in chinese materia medica
san miao san: used to treat bi zheng; consists of cangzhu, huangbai, and niuxi
san wu huangqin: herbal prepartion of s. flavescens, s. baicalensis and rehmannia glutinosa; inhibits replication of h1n1 influenza virus
san-huang-hsieh-hsin-tang: mixture of powders of rheum officinale, coptis teeta and scutellaria baicalensis
sanasol: a table salt substitute; contains 60% kcl, 10% nh4cl, 10% calcium gluconate, 5% mg asparaginate, 10% potassium citrate, and 5% glutaminic acid
sanativo: a brazilian product used to promote wound healing; consists of piptadenia colubrina, schinus terebenthifolius, physalis angulata, and cereus peruvianus
sancai: consists of 3 ancient chinese medicine prescriptions: "san cai tang," "jiao tai wan," and "fructus mume."
sanchinan-A: from roots of chinese plant panax notoginseng; arabinogalactan which shows reticuloendothelial system potentiating activity
sandal wood oil-turmeric cream: a turmeric- and sandal wood oil-containing cream that prevents radiodermatitis in head and neck cancer patients undergoing external beam radiotherapy
sandalwood oil: main constituents of east indian sandalwood oil are alpha-santalol, beta-santalol, alpha-santalene, coumarin, and alpha-terpineol
sandaracopimaric acid: a terpenoid from sagittaria sanittifolia l
sandaracopimarinol: a pill-bug repellent isolated from the japanese cedar cryptomeria japonica
sandensone A: has antineoplastic activity; isolated from the soft coral sinularia sandensis
sandoricin: from sandoricum koetjape (meliaceae); antifeedant;
sandorinic acid A: a multiflorane-type triterpenoid acid from sandoricum indicum (meliaceae)
sandorinic acid B: a multiflorane-type triterpenoid acid from sandoricum indicum (meliaceae)
sandorinic acid C: a multiflorane-type triterpenoid acid from sandoricum indicum (meliaceae)
sandrosaponin IX: from the whole plants sanicula elataham. var. chinensis makino
sang ju yin: contains folium mori, flos chrysanthemi and many others, complete list in first source
sang-tong-jian: used to treat metabolic disorders; an extract of the leaves of the mulberry morus alba
sanggenone C: inhibits tnf-alpha-stimulated adhesion between polymorphonuclear lymphocytes and synovial cells
sangor: mixture of picloram, 2,4-d; used as an herbicide
sangu: has analgesic and antineoplastic activities; consists of fructus psoraleae, rhizoma drynariae, and herba speranskiae tuberculatae
sanguiin H 11: regulates chemotaxis of neutrophil; from plant, sanguisorba officinalis
sanguiin H 6: a cytotoxic dimeric ellagitannin from sanguisorba officinalis
sanguinamide B: a modified octapeptide macrocycle from nudibranch, hexabranchus sanguineaus
sanguinarine: bactericidal produces glaucoma in laboratory animals; a phytogenic antineoplastic agent; from argemonemexicana & sanguinaria; inhibits glutamate decarboxylase
sanguinarine reductase, Eschscholzia californica: catalyzes the conversion of sanguinarine to dihydrosanguinarine
sanguinolentaquinone: red indoloquinone alkaloid from the fruiting bodies of the mushroom mycena sanguinolenta
sanguinone A: blue pyrroloquinoline alkaloid from the fruiting bodies of the mushroom mycena sanguinolenta
sanguinone B: blue pyrroloquinoline alkaloid from the fruiting bodies of the mushroom mycena sanguinolenta
sanguiritrine: rn given refers to sulfate; rn for parent cpd not avail 9/91
sanguis draxonis: the red resin derived from the wood of dracaena cochinchinensis
sanionin A: anti-inflammatory and anti-microbial agents with weak cytoxicity from the antarctic moss sanionia georgicouncinata
sanjuanolide: isoprenylated chalcone which contains an unique hydroxyisoprenyl group
sann-joong-kuey-jian-tang: consists of phellodendron amurense rupr., glycyrrhiza uralensis fisch, sparganium stoloniferum buch., curcuma aeruginosa roxb., laminaria japonica aresch, bupleurum scorzoneri folium willd, coptis chinensis franch, angelica sinensis diels, cimicifuga heracleifolia komar, trichosanthes cucumeroides maxim, anemarrhena asphodeloides bunge, scutellaria baicalensis georgi, gentiana scabra bunge, platycodon grandiflorus, forsythia suspensa vahl, paeonia lactiflora pall and pueraria lobata ohwi
sannamycin B glycyltransferase: catalyzes glycylation of sannamycin b to sannamycin a, the active cpd in streptomyces sannanensis ifo 14239
sannanine: antineoplastic antibiotic isolated from streptomyces sannanensis
sannoshashinto: contains coptis japonica rhizome, whose main ingredient is berberine, scutellaria baicalensis roots, whose main ingredients are baicalin & baicalein & rheum tanguticum rhizome, whose main ingredients are sennosides & tannins; showed strong antioxidative effects in vitro on hypercholesterolaemic rabbits
sano protein, Drosophila: binds dishevelled protein; refseq nm_166314
sanpi pingwei: consists of 13 herbs, including scytekaruabarbvata d. don, fissistigma glaucescens (hance) merr., radix astragali, radix glycyrrhizae, rhizoma pinelliae, and fructus aurantii immaturus
sanqi: used to treat kidney disease; contains astragalus membranaceus and panpax notoginseng
sansalvamide A: a cyclic depsipeptide; inhibits poxvirus topoisomerase
sansevistatin 1: spirostanol saponin from sansevieria ehrenbergii
sansevistatin 2: spirostanol saponin from sansevieria ehrenbergii
sanshool: isolated from the stem bark of zanthoxylum liebmannianum; rn given for (e,e,z,e)-isomer
sansurdal: combination of vitamin b1,b2,b6, methionine & histidine
santa-maria protein, Drosophila: amino acid ; refseq nm_164752
santacruzamate A: hdac2 inhibitor from the panamanian marine cyanobacterium cf. symploca sp.
santicizer 148: isodecyldiphenyl phosphate & triphenyl phosphate mixture
sanumgerman: complex of germanium, citrate, ascorbate, potassium and succinate
sanyang xuedai: a traditional chinese antitumor drug consisting of fructus amomi, sanguis draconis, angelicae sinensis, rhizoma glycyrrhizae, poria cocos, ginger, rhizoma dioscoreae, and rhizoma notoginseng; enhances sensitivity of lung cancer cells to radiation
sanye tablet: contains mori folium (morus alba l., leaf), nelumbinis folium (nelumbo nucifera gaertn., leaf), crataegi folium(crataegus pinnatifida bunge, leaf), paeoniaeradix rubra (paeonia lac-tiflora pallorpaeonia veitchii lynch,root), salviae miltiorrhizae radixet rhizoma (salvia miltiorrhiza bunge, root and rhizome), and is employed as a hypolipidemic in traditional chinese medicine
sanyrene: solution of fatty acid esters hyperoxygenated; prevents decubiti ulcer
sanyuansan: has antidepressant activity; consists of ginseng total saponins, fish oil, and valeriana
sapecin B protein, Sarcophaga peregrina: amino acid sequence given in first source; isolated from the flesh fly sarcophaga peregrina; blocks macroscopic k+ currents
sapecin C protein, Sarcophaga peregrina: amino acid sequence given in first source; isolated from the flesh fly sarcophaga peregrina
sapecin protein, Sarcophaga: contains 40 amino acid residues; the gene for the sapecin precursor is activated in the hemocytes of the third instar larvae of sarcophaga in response to bodily injury
sapindoside B: isolated from locinera fulvotomentosa; ; rn given refers to (3beta,4alpha)-isomer; rn for cpd without isomer designation not avail 12/89
sapindosine: fulvotomentoside from flower of lonicera fulvotomentosa
sapinopyridione: a phytotoxic 3,3,6-trisubstituted-2,4-pyridione produced by sphaeropsis sapinea
sapintoxin A: from unripe fruits of sapium indicum; rapidly acting proinflammatory agent on mammalian skin, but considerably less potent than tetradecanoylphorbol acetate
sapintoxin D: rn given refers to (1ar-(1aalpha,1bbeta,4abeta,7aalpha,7balpha,8alpha,9beta,9aalpha))-isomer; rn for cpd without isomeric designation not avail 9/90
saponaceolide B: isolated from the fruiting bodies of the toxic mushroom t. terreum
saponaceolide M: isolated from the fruiting bodies of the toxic mushroom t. terreum
saponin E, hupehensis: ; hederagenin from anemone hupehensis
saponin Rb1, Panax notoginsenoside: modulates akt-mtor-pten signaling; has neuroprotective effects in rats following ischemic stroke
saposhnikovan C: isolated from saposhnikovia divaricata; composed of d-galacturonic acid:l-rhamnose:l-arabinose:d-galactose in a ration of 27:7:8:8
sapotexanthin: an a-provitamin carotenoid from red mamey (pouteria sapota)
sappanchalcone: rn given from toxline; rn not in chemline 3/85
saprionide: a new anhydride-type compound from the roots of salvia prionitis (labiatae)
sapriparaquinone: diterpenoid quinone isolated from salvia prionitis; ; shows cytotoxicity to p388 leukemia cells
saprirearine: a tricyclic diterpene from the roots of salvia prionitis (labiatae)
saprosmine A: cytotoxic; from the stem of saprosma hainanense
saprosmine B: cytotoxic; from the stem of saprosma hainanense
saquayamycin: isolated from streptomyces nodosus mh190-16f3
saquayamycin B: isolated from streptomyces nodosus mh190-16f3
saquayamycin C: isolated from streptomyces nodosus mh190-16f3
saquayamycin D: isolated from streptomyces nodosus mh190-16f3
sara protein, Drosophila: whose main function seems to be equally distributing components of the transforming growth factor- (tgf-) signaling pathway during cell division
saracoside: an antileishmanial agent that inhibits topoisomerase ib
sarafotoxin-c: a highly toxic vasopressor peptide from atractaspis; amino acid sequence has been determined
sarafotoxins s6: several isotoxins from atractaspis engaddensis; has strong cardiotoxic activity; all contain 21 amino acid residues; see also endothelium-derived vasoconstrictor factor, endothelins
saramycetin: polypeptide antifungal antibiotic produced by a species of streptomyces
sarasinoside A1: isolated from palauan marine sponge asteropus sarasinosum
sarasinoside B1: isolated from palauan marine sponge asteropus sarasinosum;
sarasinoside C1: isolated from palauan marine sponge asteropus sarasinosum
saratin: a recombinant protein, isolated from the saliva of the leech hirudo medicinalis; a potent inhibitor of vwf-dependent platelet adhesion to collagen and hence may have therapeutic potential as an antithrombotic agent
sarcalumenin: amino acid sequence has been determined; rn given refers to rabbit clone pgpn1 protein moiety reduced
sarcoglycan, zeta, human: mutations are unlikely to be associated with myoclonus dystonia; refseq nm_139167
sarcolamban protein, Drosophila: pncr003-2l - putative noncoding rna 003 in 2l
sarcolectin: specific for galacturonic acid, (d)-isomer; interferon antagonist protein from hamster sarcoma & normal muscle which agglutinates normal & transformed cells; major ligand in human placenta is macrophage migration-inhibitory factors;
sarcolipin: proteolipid of skeletal muscle sarcoplasmic reticulum; amphipathic 31-residue peptide; amino acid sequence given in first source
sarcoma glycoprotein gp96 rejection antigens: polymorphic tumor antigen of chemically induced sarcoma from inbred mice; induce transplantation resistance to tumor challenge in the inbred strain of origin; nucleotide sequence & deduced amino acid sequence given in first source; do not confuse with grp94
sarcoma-associated antigen S1: a heterophile antigen present on human sarcoma cell lines in culture; mw 70 kda; amino acid sequence has been determined
sarcomeginal: a hormonal antineoplastic agent; isolated from sarcomelicope megistophylla
sarcophagine synthetase: requires mg(+2) & atpase as cofactors
sarcophytol B: ; isolated from a soft coral sarcophyton gluacum
sarcophytolide: a neuroprotective compound from the soft coral sarcophyton glaucum
sarcophytonamine: from the hainan soft coral sarcophyton crassocaule
sarcophytonone: from the hainan soft coral sarcophyton crassocaule
sarcophytoxide: a 14-membered marine cembranoid from sarcophyton glaucum
sarcosin protein, mouse: a kelch repeat protein that promotes lateral fusion of myofibril assembly intermediates; genbank al929083
sarcosine dimethylglycine methyltransferase, Halorhodospira halochloris: involved in the formation of glycine betaine
sarcosine dithiocarbamate: protects against toxicity of alkylating agents
sarcosine reductase: involved in sarcosine metabolism in eubacterium acidaminophilum
sarcosine-arginyl-valyl-tyrosyl-lysyl-histidyl-prolyl-alanine: a beta-arrestin biased ligand of the angiotensin ii type 1 receptor that engages beta-arrestin2 recruitment
sarcostin: rn given for (3beta,12beta,14beta,17alpha,20s)-isomer
sarcostolide E: from the taiwanese soft coral sarcophyton stolidotum; exhibited weak to moderate cytotoxic activity against human widr and daoy tumor cell lines
sarcotoxin I protein, Sarcophaga peregrina: bactericidal protein from hemolymph of sarcophaga peregrina (flesh-fly) larva; mw 5000; mixture of sarcotoxin ia, ib, ic
sarcotoxin IIA protein, Sarcophaga peregrina: from hemolymph of third instar of sarcophaga peregrina; mw 24,000
sarcotoxin IIB protein, Sarcophaga peregrina: from hemolymph of third instar of sarcophaga peregrina
sarcotoxin IIC protein, Sacrophaga peregrina: from hemolymph of third instar of sacrophaga peregrina
sarcotoxin III protein, Sarcophaga peregrina: from hemolymph of third instar larvae of sarcophaga peregrina; mw 7kda
sardaine Z1: amino acid sequence given in first source; isolated from the striped bonito sarda orientalis; differs from sardaine z2 by having serine at position 7 replaced by alanine
sardaine Z2: amino acid sequence given in first source; isolated from the striped bonito sarda orientalis; differs from sardaine z1 by having alanine in position 7 replaced by serine
sargachromanol G: isolated from the brown algae sargassum siliquastrum
sargachromanol I: an alpha-amylase inhibitor isolated from myagropsis myagroides
sargachromenol: nerve growth factor-potentiating substance from sargassum macrocarpum
sargahydroquinoic acid: vasodilatator from the brown alga sargassum macrocarpum
sargaquinoic acid: isolated from the brown alga sargassum macrocarpum
sargassopenilline H: from the alga-derived fungus penicillium lividum
sargassumol: an antioxidant and free radical scavenger isolated from the brown alga sargassum micracanthum
sargent gloryvine: decoction for treatment of severe acute pancreatitis;contains sargent gloryvine, patrinia, dandelion, peach kernel, peony, astragalus membranaceus and codonopsis pilosula
sargramostim: a glycosylated form of recombinant gm-csf; used to treat drug-induced agranulocytosis
sarilumab: antibody against il-6ralpha in patients with rheumatoid arthritis
sarniensine: mesembrine-type alkaloid from nerine sarniensis, with larvicidal and adulticidal activities against aedes aegypti
sarocladione: 5,10:8,9-diseco-steroid from the deep-sea-derived fungus sarocladium kiliense
saroclazine A: isolated from mangrove-derived fungi sarocladium kiliense hdn11-84; has cytotoxic properties
saroclazine B: isolated from mangrove-derived fungi sarocladium kiliense hdn11-84; has cytotoxic properties
saroclazine C: isolated from mangrove-derived fungi sarocladium kiliense hdn11-84; has cytotoxic properties
sarpicillin: ampicillin ester; rn given refers to (2s-(2 alpha,5 alpha,6 beta))-isomer: 40966-79-8
sarracine: rn given refers to (1s-(1alpha(z),7alpha(z),7abeta))-isomer
sars7a protein, SARS virus: a unique group-specific protein (u122) of the severe acute respiratory syndrome coronavirus
sarsasapogenin: rn given refers to cpd without isomeric designation; a neurotrophic factor
sarsasapogenone: rn given refers to (5beta,25r)-isomer
sarsasapogenyl arabinopyranosyl-(1-4)-(arabinopyranosyl-(1-6))glucopyranoside: has antineoplastic activity
sarsasapogenyl glucopyranosyl-(1-4)-(arabinopyranosyl-(1-6))glucopyranoside: has antineoplastic activity; isolated from smilax officinalis
sarsasapogenyl glucopyranosyl-(1-4)-(glucopyranosyl-(1-6))glucopyranoside: has antineoplastic activity
sartorypyrone A: produced by neosartorya fischeri fo-5897.
sartorypyrone D: produced by neosartorya fischeri fo-5897.
satietin: serum glycopeptide with 87% carbohydrate, 12.8% amino acids and anorectic activity
satiomem: a plant proteoglycan; from the membranes of mono- and dicotyledonous plant sprouts; mw 50-kda; consists of 70-85% carbohydrates and 15-20% proteins
sativanone: a biomarker for the anti-senescence properties of dalbergia odorifera extract
sativenediol: rn given refers to (1r-(1alpha,2beta,3beta,4alpha,7alpha,7abeta))-(1r,2beta)-isomer
sativin protein, Pisum sativum: an antifungal miraculin-like protein isolated from legumes of the sugar snap pisum sativum var. macrocarpon; amino acid
satralizumab: humanized monoclonal antibody targeting the interleukin-6 receptor
satratoxin H: toxic metabolite of stachybotrys atra; see also record for satratoxin g
satratoxin H 12',13'-diacetate: an antimalarial agent isolated from ficus fistulosa and rhaphidophora decursiva
satratoxin H 13'-acetate: an antimalarial agent isolated from ficus fistulosa and rhaphidophora decursiva
saturated steroid 6-alpha-hydroxylase: acts on 5 alpha-androstane-3 beta,17 beta-diol and 5 alpha-pregnan-3 beta-ol-20-one; possibly does not require cytochrome p-450
saturnisporin SA II: from trichoderma saturnisporum; composed of four 20-residue peptaibols (aib-containing liner peptides with c-terminal amino alcohol); amino acid sequence given in first source
saturnisporin SA IV: an alpha-aminoisobutyric acid-containing peptaibol containing 20-amino acid residues; isolated from trichoderma species; interacts with neutral small unilamellar vesicles and induces leakage of entrapped material; amino acid sequence given in first source
sau protein, Drosophila: a phosphatidylinositol 4-phosphate effector; refseq nm_134814
saucerneol D: has antioxidant, anti-infllammatory, and antiasthmatic activities; a sesquilignan isolated from saururus chinensis
saucernetilignan-8: isolated from saururus chinesis, has significant anti-inflammatory effect
saucernetin-7: isolated from saururus chinensis; inhibits the lps-induced production of nitric oxide and prostaglandin e2 in macrophage raw264.7 cells
saucernetin-8: isolated from saururus chinensis; inhibits the lps-induced production of nitric oxide and prostaglandin e2 in macrophage raw264.7 cells
saurine: isolated from fish may be histamine salt; causes scombroid poisoning; no other info available 1/14/80
sauristolactam: lactam of 10-aminomethyl-3-hydroxy-4-methoxyphenanthrene-1-carboxylic acid isolated from saururus cernuus
sauroine: isolated from huperzia saururus with activity in wistar rats in electrophysiological and behavioral assays related to memory retention
saurufuran A: from the root of saururus chinensis (saururaceae)
saurufuran B: from the root of saururus chinensis (saururaceae)
sauvagine: isolated from skin of south american hylid frog, phyllomedusa sauvagei; has hypotensive & antidiuretic effect; potent stimulating action on secretion of acth & corticosterone; inhibitory effect on secretion of prl, gh, & tsh; consists of straight chain of 40 amino acid residues
sauvagine (11-40), 4-(1-azi-2,2,2-trifluoroethyl)benzoyl-His(12)-: a corticotropin-releasing factor type 2 (crf2) receptor antagonist; amino acid
sav protein, Drosophila: promotes both cell cycle exit and apoptosis in drosophila; amino acid ; refseq nm_176544
savignin protein, Ornithodoros savignyi: a potent thrombin inhibitor isolated from the salivary glands of the tick ornithodoros savignyi; refseq af321524
savignygrin protein, Ornithodoros savignyi: a platelet aggregation inhibitor isolated from the soft tick ornithodoros savignyi; genbank af452885 and af452886
savinin: a lignan from pterocarpus santalinus inhibits tumor necrosis factor-alpha production and t cell proliferation
savirin: savirin - staphylcoccus aureus virulence inhibitor; inhibits agr quorum sensing
sawD protein, Streptomyces ansochromogenes: related to the differentiation of streptomyces ansochromogenes; amino acid
sax protein, Drosophila: a serine-threonine kinase receptor of the tgf-beta superfamily; from drosophila; amino acid sequence given in first source; genbank u05209
saxatilin: a 7.7-kda disintegrin from gloydius saxatilis venom; amino acid
saxifragifolin B: has antineoplastic activity; isolated from androsace umbellata
saxifragifolin C: has antineoplastic activity; isolated from androsace umbellata
sazetidine-A: a ligand that desensitizes alpha4beta2 nicotinic acetylcholine receptors without activating them
sb protein, Drosophila: a 786 amino residue type ii transmembrane serine protease; it acts through its proteolytic extracellular domain to detach imaginal disc cells from extracellular matrices & it transmits an outside-to-inside signal to its intracellular domain to modify the cytoskeleton & facilitate cell shape changes underlying morphogenesis; amino acid sequence given in first source; genbank l11451
sbb protein, Drosophila: encodes a product involved in axon guidance which is localised to the nucleus; it is expressed in the embryonic cns, adult abdomen, head and thorax; affects larval locomotory behavior in drosophila; amino acid
sbcD protein, E coli: amino acid sequence given in first source; degrades single-stranded dna from the 3' end
sboA protein, Bacillus subtilis: 35-amino acid cyclic peptide with three cysteine bridges from bacillus subtilis 168; peptide from bacillus amyloliquefaciens is idential to that from b. subtilis; has bacteriocidal activity against some gram-positive bacteria such as listeria, some species of bacillus and e.faecium; genbank aj430547
sbsA protein, Bacillus stearothermophilus: a 130-kda surface-layer (s-layer) protein isolated from bacillus stearothermophilus; amino acid ; genbank x71092
sc protein, Drosophila: involved in peripheral nervous system development; also a cell-automonomous genetic factor involved in sex determination; a member of the achaete-scute complex; isolated from drosophila; has been sequenced; refseq nm_057455
sc-538 antibody, human: cross-reacts with cytoskeletal proteins that could be misinterpreted as npr isoforms. such misinterpretation has confused the progesterone response literature
sc4 protein, sonchus yellow net virus: isolated from the plant rhabdovirus sonchus yellow net virus
scFV green fluorescent protein, recombinant: scfv single chain antibody against lipopolysaccharide of outer cell wall of gram-negative bacteria
scFv 421: a single-chain antibody which specifically binds the tumor suppressor protein p53; amino acid sequence given in first source
scFv 425: binds egf receptor; derived from monoclonal antibody 425
scFv 763.74: a single-chain antibody fragment derived from the monoclonal anti-high molecular weight-melanoma associated antigen antibody 763.74; amino acid
scFv fragment SW1: single-chain antibody fragment directed against the dimeric leucine zipper domain; genbank y16621-2 (variable region heavy and light chains)
scFv(FRP5)-ETA antibody toxin: a recombinant antibody toxin derived from pseudomonas exotoxin a; used to treat solid malignomas
scFvC54-sTRAIL fusion protein: consists of human soluble tumor necrosis factor-related apoptosis-inducing ligand (trail) fused to scfvc54; has anti-tumor bystander activity
scFvCD33-sTRAIL protein: a synthetic anti-leukemia protein
scFvMEL-TNF fusion protein: derived from tumor necrosis factor and single-chain fv antibody scfvmel; targets gp240 antigen
sca protein, Drosophila: involved in neurogenesis; fibrinogen-related lateral inhibitor during eye development; refseq nm_057362
scaA protein, Aspergillus: involved in sensitivity to camptothecin in aspergillus nidulans; genbank af228504
scabequinone: from cyperus distans l; inhibits seed germination and seedling growth
scabiostellatoside: isolated from the whole plant of scabiosa stellata l; scabiostellatoside f has cytotoxic activity against a tumor cell line
scabronine M: inhibitor of ngf-induced neurite outgrowth from pc12 cells from the fruiting bodies of the mushroom sarcodon scabrosus
scaffold attachment factor B1, mouse: involved in rna processing and stress response; has been sequenced
scaffold protein, Herpes simplex virus-1: encoded by overlapping in-frame ul26 and ul26.5 transcripts; essential for formation and efficient maturation of capsids; n-terminal protease domain, and its c-terminal oligomerization and capsid protein-binding domains are identical to those of ul26.5. the ul26 protease cleaves itself, releasing minor scaffold proteins vp24 and vp21protease cleavage produces two polypeptides, prn and icp35a; do not confuse with hsv-1 assembly protein icp35
scagel: a gel preparation for preventing scar formatino; consists of allium cepa, centella asiatica, aloe vera, broussonetia papyrifera, and nanohydroxyprolisilane
scalaradial: rn refers to the (5alpha,12alpha,17abeta)-isomer; a marine natural product isolated from the sponge cacospongia sp.
scalarinol: cytotoxic; from the saudi red sea sponge hyrtios erectus
scalusamide A: pyrrolidine alkaloid from the marine-derived fungus penicillium citrinum
scalusamide B: pyrrolidine alkaloid from the marine-derived fungus penicillium citrinum
scalusamide C: pyrrolidine alkaloid from the marine-derived fungus penicillium citrinum
scambio protein, human: a guanine nucleotide exchange factor for rho; gene is located on chromosome 14q11.1, encoding a protein of around 181 kda that is highly expressed in both heart and skeletal muscle
scandenolide: a sesquiterpene lactone leukotriene b4 antagonist from mikania cordata
scarabaecin protein, Oryctes rhinoceros: an antifungal protein isolated from the coconut rhinoceros beetle oryctes rhinoceros; amino acid
scarf protein, Dugesia tigrina: encoding a soluble c-type lectin consisting of two slightly different carbohydrate-recognition domains; amino acid ; genbank z66536
scavidin: constructed from avidin and macrophage scavenger receptor class a; may serve as vehicle for targeted biotinylated molecule delivery
scb-1 protein, C elegans: refseq nm_001269370.1
scd1 protein, S pombe: schizosaccharomyces pombe homolog of saccharomyces cdc24 protein; genbank u12538
scd2 protein, S pombe: schizosaccharomyces pombe homolog of saccharomyces bem1 protein; amino acid sequence given in first source; genbank u12539
sced protein, Drosophila: coordinates microtubule-independent actin reorganization in drosophila; has been sequenced
sceliphrolactam: a 26-membered polyene macrocyclic lactam from a wasp-associated streptomyces sp.
sceptrin: ; isolated from marine sponges of the genus agelas; rn from chemline
sceptrumgenin 3-O-lycotetraoside: from polygonatum orientale
scequinadoline A: fumiquinozaline isolated from marine-derived fungus dichotomomyces cejpii; inhibits dengue virus serotype 2 production
schefflone: a trimeric monoterpenoid from the root bark of uvaria scheffleri
schiglautone A: antineoplastic from the stems of schisandra glaucescens
schisandrol A: dibenzocyclooctadiene lignan from schisandra chinensis
schisandrolic acid: induces apoptosis; isolated from schisandra propinqua
schisanhenol: a dibenzyl cyclooctane from kernels of schisandra rubriflora
schisanlactone A: an hiv-1 protease inhibitor with antineoplastic activity; isolated from kadsura longipedunculata
schisanlactone H: from the fruits of schisandra sphenanthera (schisandraceae)
schisantherin B: lignan isolated from fruit of schisandra sphenanthera; rn given refers to schisanterin b and gomisin b
schisanwilsonene A: anti-hbv sesquiterpenoid from the fruits of schisandra wilsoniana
schisanwilsonene B: anti-hbv sesquiterpenoid from the fruits of schisandra wilsoniana
schisanwilsonene C: anti-hbv sesquiterpenoid from the fruits of schisandra wilsoniana
schisphenin A: a hepatoprotective agent isolated from schisandra arisanensis
schistatin, Echis carinatus: a disintegrin homodimer from saw-scaled viper ; amino acid
schistomyotropin-1: from cns of locust, schistocerca gregaria; amino acid
schistomyotropin-2: from cns of locust, schistocerca gregaria; amino acid
schistosomin: antagonist of calfluxin; present in hemolymph of snails infected by trichobilharzia ocellata; causes hypersensitivity reactions in schistosomiasis patients
schistostatin: an allatostatin-like peptide from locust, schistocerca gregaria; amino acid sequence given in first source; genbank z58819
schizandrer A: from fructus schizandrae chinensis (schisandraceae)
schizandrin: a dibenzocyclooctadiene lignan; schizandra is the plant name
schizandrin A: the major lignan, 2-9%, of schisandra plant; has hepatoprotective, antioxidant, and antineoplastic activities
schizandrin B: a phytogenic antineoplastic agent with anti-inflammatory activity; isolated from schisandra plant
schizandrin C: from schizandra chinensis baill & fructus schisandrae; protects liver from carbon tetrachloride injury;
schizandrol B: from schizandra chinensis, plant used as tonic in traditional chinese medicine
schizandrol D: from the fruits of schisandra chinensis, inhibits proprotein convertase subtilisin/kexin type 9 expression
schizogynine: from schizozygia coffaeoides (apocynaceae)
schizolaenone A: cytotoxic flavanones of schizolaena hystrix from the madagascar rainforest
schizolaenone B: cytotoxic flavanones of schizolaena hystrix from the madagascar rainforest
schizopeptin 791: anabeanopeptin-like cyclic peptide from the cyanobacterium schizothrix sp.
schlafen-1 protein, mouse: induces growth arrest in t-lymphocytes and arrests nih3t3 fibroblasts priior to g1/s transition; genbank af099972
schlafen-4 protein, mouse: an aaa domain-containing modulator of myelopoiesis; genbank bc044865
schumannificine: isolated from the rootbark of schumanniophyton magnificum
schumanniofioside A: chromone glycoside from schumanniophyton magnificum
schumanniofioside B: ; chromone glycoside from schumanniophyton magnificum (rubiaceae)
schweinfurthin A: a geranyl stilbene from plant macaranga schweinfurthii
schweinfurthin B: a geranyl stilbene from plant macaranga schweinfurthii
schweinfurthin C: a geranyl stilbene from plant macaranga schweinfurthii
schweinitzin A: cytotoxic; from the vietnamese fungus xylaria schweinitzii
schweinitzin B: cytotoxic; from the vietnamese fungus xylaria schweinitzii
sciadopitysin: biflavonoid from taxus celebica & ginkgo biloba
scillaren: minor descriptor (75-80); on-line & index medicus search cardiac glycosides (75-80) & squill (66-74); consists of scillaren a & scillaren b; rn given refers to cpd with unknown mf; see also record of scillaren a
scillascilloside E-1: antitumor cpd from the fresh bulbs of scilla scilloide
scillicyanoside: rn given refers to (5beta,16beta)-isomer
scinderin: a calcium-dependent actin filament-severing protein; amino acid sequence known
scirpusin A: from the rhizome of scirpus fluviatilis and xinjiang wine grape; structure in first soource
scirpusin C: a dimeric stilbenoid from the seeds of syagrus romanzoffiana
sclareolide: has antineoplastic activity; synthesized by oxidation of sclareol; a minor constituent of arnica angustifolia and sideritis nutans
sclerienone A: isolated from the methylene chloride/methanol extract of the rhizome
sclerienone B: isolated from the methylene chloride/methanol extract of the rhizome
scleritodermin A: a cytotoxic cyclic peptide from the lithistid sponge scleritoderma nodosum
sclerominol: a 1-hydroxy-2,6-pyrazinedione associated with hypovirulent isolates of sclerotinia minor, a fungal plant pathogen associated with lettuce drop and other plant diseases
sclerotan: extracellular beta-glucan from sclerotinia sclerotiorum with immunomodulating and antitumor activity
sclerotiamide: related to the paraherquamides; isolated from the sclerotia of aspergillus sclerotiorum
sclerotide A: from marine-derived fungus, aspergillus sclerotiorum pt06-1
sclerotide B: from marine-derived fungus, aspergillus sclerotiorum pt06-1
sclerotin: protein in exoskeleton of insects and in shells of crustaceans
sclerotionigrin B: has antineoplastic activity; isolated from aspergillus sclerotioniger
sclerotiorin: isolated from monoverticillate penicillia; rn given for (r-(r*,s*-(e,e)))-isomer
scolexin protein, Manduca sexta: coagulation-provoking immune protein; may be a new subfamily of chymotrypsin-like serine proteases; genbank af087004 (scolexin a) and af087005 (scolexin b)
scolochinenoside C: a snake venom phosphodiesterase i inhibitor; isolated from scolopia chinensis
scolopendin 1, Scolopendra subspinipes: from adult centipede
scolopendra alkaloids: used to treat rheumatoid arthritis (ra) in china
scolopendrasin X, Scolopendra subspinipes mutilans: from centipede scolopendra subspinipes mutilans
scolopianate A: a snake venom phosphodiesterase i inhibitor; isolated from scolopia chinensis
scolopin-2: isolated from centipede venom; is cytotoxic toward cervical cancer cells
scombrine: from mackerel, scomber australasicus (gamma) & s. scombrus (alpha); 34 amino acid residues; mw 4.5 kda; amino acid
scombrotoxin: toxin which accumulates in the flesh of fish during storage; associated with high levels of histamine in the fish flesh
scopadulcic acid A: from scoparia dulcis (scrophuraliaceae)
scopadulciol: inchikey: cfpmrjftbkycrr-uhfffaoysa-n
scopoletin peroxidase: used to determine monoamine oxidase activity of thrombocytes
scopularide A: found in the fungus scopulariopsis brevicaulis, which was isolated from the marine sponge tethya aurantium
scopularide B: found in the fungus scopulariopsis brevicaulis, which was isolated from the marine sponge tethya aurantium
scordinin: main tonic principle active in garlic; complex substance assayed by fixed amount of lactacte hydrolyzed by lactate dehydrogenase
scorpine: 75 aa, 8350 da peptide from venom of pandinus imperator; amino acid
scorpinone: a natural azaanthraquinone produced by a bispora-like tropical fungus
scorpion neurotoxin BmK M2: neurotoxin from the scorpion buthus martensii karsch; amino acid
scorpion toxin AaH III: amino acid sequence known; from androctonus australis hector
scorpion toxin AaH IT1: active only in insects; from androctonus australis; amino acid sequence given in first source
scorpion toxin AaH IT2: active only in insects; from androctonus australis; amino acid sequence given in first source
scorpion toxin AaH IT4: from androctonus australis; anti-insect toxin; amino acid sequence given in first source
scorpion toxin AaIT5: an insect-selective toxin from the venom of north african scorpion, androctonus australis; mw 6.8 kda; has homology with aait4; amino acid sequence given in first source
scorpion toxin Aah VI: a n-glycosylted anti-insect toxin from scorpion; amino acid
scorpion toxin CsE-I: from centruroides sculpturatus; amino acid
scorpion toxin CsE-V: shows 45% sequence homology to north africa alpha-toxin aah-ii; amino acid sequence given in first source
scorpion toxin Css II: from centruroides suffusus suffusus; protein conformation given in first source
scorpion toxin I'': lethal to mice; differs from toxin i of the same scorpion by an extra arginine residue at the c-terminal end
scorpion toxin I, Androctonus: from androdoctonus australis hector
scorpion toxin II, Androctonus: from androctonus australis; 64-amino acid peptide, mw 7249
scorpion toxin II, Tityus: a beta-type toxin from the scorpion tityus serrulatus; amino acid sequence given in first source
scorpion toxin Ts1, Tityus: a beta-type toxin from the scorpion tityus serrulatus; amino acid
scorpion toxin receptor: androctonus australis; hector neurotoxin ii receptor
scorpion venom P05: amino acid sequence given in first source; isolated from the scorpion androctonus mauretanicus mauretanicus; 87% homology with leiurotoxin i
scorpion venom P05-NH2: the c-terminal carboxyl-amidated analog of p05
scorzocreticin: from the greek endemic species scorzonera cretica (compositae)
scorzocreticoside I: from the greek endemic species scorzonera cretica (compositae)
scorzocreticoside II: from the greek endemic species scorzonera cretica (compositae)
scotchguard: a commercially available product that contains 1,1,1-trichloroethane and fluorocarbons
scotophobin: minor descriptor (73-85); on-line & index medicus search peptides (73-85); rn given refers to all (l)-isomer
scrR protein, bacteria: do not confuse with scr protein from drosophila; negatively controls the scr regulon; aa sequence given in first source; genbank x67751
screlotiumol: has antineoplastic activity; isolated from the fungus screlotium rolfsii
scrib protein, zebrafish: has dual roles of zygotic and maternal scribble1 in neural migration and convergent extension movements in zebrafish embryos; refseq nm_001007175
scrobiculin, Lobaria scrobiculata: from the lichen lobaria scrobiculata
scrokoelziside A: a triterpene glycoside isolated from scrophularia koelzii
scrophuloside B: from the rhizomes of neopicrorhiza scrophulariiflora (scrophulariaceae)
scropolioside D: an iridoid glycoside from aerial parts of scrophularia ilwensis; ; antidiabetic agent
scroside A: phenylethanoid glycoside isolated from picrorhiza scriphulariiflora;
scroside B: phenylethanoid glycoside isolated from picrorhiza scriphulariiflora;
scroside C: phenylethanoid glycoside isolated from picrorhiza scriphulariiflora;
scrovalentinoside: an iridoid glycoside from scrophularia auriculata
scrt protein, Drosophila: from drosophila; closely related to sna (snail) protein; promotes adult neurogenesis; amino acid sequence given in firstsource; genbank u36477; do not confuse with sex comb reduced protein also refered to as scr protein; refseq nm_079187
scruin protein, Horseshoe Crab: a limulus acrosomal process protein; a 103-kd protein related to the protein kelch; has been sequenced; alpha & beta are two isoforms
scu protein, Drosophila: an essential gene product of drosophila, homologous to mammalian mitochondrial type ii l-3-hydroxyacyl-coa dehydrogenase/amyloid-beta peptide-binding protein; genbank y15102
scutalbin C: has been isolated from the acetone extract of the aerial parts of scutellaria sieberi
scutan: temporary crown & bridge material; dental resin consisting of an ethyleneimine monomer which may be a derivative of bisphenol a, a polyamide filler, & cross-linking catalyst methyl-4-methyl benzenesulfonate
scutebarbatine A: has antineoplastic activity; isolated from scutellaria barbata
scutebarbatine O: cytotoxic alkaloid from the whole plant of scutellaria barbata
scutebatin A: from scutellaria barbata, with inhibitory effects on lps-induced nitric oxide production
scutebatin B: from scutellaria barbata, with inhibitory effects on lps-induced nitric oxide production
scutebatin C: from scutellaria barbata, with inhibitory effects on lps-induced nitric oxide production
scutecyprol A: has been isolated from the acetone extract of the aerial parts of scutellaria sieberi
scuteflorin A: from scutellaria lateriflora; scuteflorin b is the 3'r isomer
scutelarin: enzyme that cleaves prothrombin to thrombin & two inactive fragments; do not confuse with the scutellarin flavonoid; not inhibited by diisopropyl fluorophosphate, mercurials & iodoacetate; does not hydrolyze arginine esters; specificity similar to ec 3.4.21.6; formerly ec 3.4.99.28
scutelinquanine D: cytotoxic cpd from scutellaria barbata
scutellarein: aglycone of scutellarin from scutellaria baicalensis; carthamidin is 2s isomer of scutellarein; do not confuse with isoscutellarein and/or isocarthamidin which are respective regioisomers, or with the scutelarin protein
scutellarein tetramethyl ether: from siam weed (chromolaena odorata) extract; structrure in first source
scutellarin-7-O-glucuronide: isolated from erigeron breviscapine
scuterivulactone D: diterpene lactone isolated from scutellaria rivularis wall.
scutestrigillosin D: cytotoxic cpd from scutellaria strigillosa
scutestrigillosin E: cytotoxic cpd from scutellaria strigillosa
scutianine C: isolated from the stem bark of zizyphus jujuba (rhamnaceae)
scutiaquinone A: perylenequinone from the roots of scutia myrtina with anthelmintic activity
scutiaquinone B: perylenequinone from the roots of scutia myrtina with anthelmintic activity
scutifoliamide A: antifungal from piper scutifolium and piper hoffmanseggianum; structure in first soruce
scutifoliamide B: antifungal from piper scutifolium and piper hoffmanseggianum; structure in first soruce
scutione: a norquinonemethide triterpene with a netzahualcoyene type skeleton; isolated from the root bark of maytenus scutioides
scutoxin A: from venom of notechis scutatus scutatus; a & b are isoforms of each other
scyliorhinin II: tachykinin from dogfish gut; selective radioligand for the tachykinin nk3 receptor in rat
scymnol sulfate ester: from gall bladder of rhizoprionodon acutus
scyphostatin: a neutral sphingomyelinase inhibitor isolated from trichopeziza mollissima
scyptolin A: cyclodepsipeptide from scytonema hofmanni; amino acid
scyptolin B: cyclodepsipeptide from scytonema hofmanni; amino acid
scytalidamide B: from a marine fungus of the genus scytalidium
scytalone dehydratase: converts scytalone to 1,3,8-trihydroxynaphthalene; on path to melanin biosynthesis
scytonemide A: cyclic peptide with 20s proteasome inhibitory activity from cyanobacterium scytonema hofmanii
scytonemide B: cyclic peptide with 20s proteasome inhibitory activity from cyanobacterium scytonema hofmanii