NLK-NML/MeSH-CZ-2025-notes huggingface dataset:
glyoxalase III: a single enzyme that converts methylglyoxal into d-lactate without involvement of glutathione; glyoxalase i and glyoxalase ii are separate enzymes which with glutathione are both required in the conversion of methylglyoxal to lactate
glyoxalbis(N(4)-methylthiosemicarbazonato)copper(II): delivers copper ion to neurons
glyoxylate 2,4-dinitrophenylhydrazone: from allantoin
glyoxylate aminotransferase: various amino acids can serve as amino donors; with serine it is ec 2.6.1.45; best donors for rat liver & kidney enzyme are leucine & phenylalanine
glyoxylate dehydrogenase (acylating): reduces glyoxylate in the presence of coa & nadp+ to yield oxalyl-coa & nadph
glyoxylate reductase: the human gene encodes an enzyme with hydroxypyruvate reductase, glyoxylate reductase, and d-glycerate dehydrogenase enzymatic activities. the enzyme has widespread tissue expression and has a role in metabolism. type ii hyperoxaluria is caused by mutations in this gene; refseq nm_012203
glyoxylate reductase (NADP+): catalyzes reversibly the oxidation of glycollate to glyoxylate in the presence of nadp
glyoxylate synthetase: catalyses the condensation of two formate molecules into glyoxylate; a tetramer with mw of 160 kda with a subunit mw of 40 kda; isolated from green potato-tuber chloroplasts
glyptopetolide: a ursane type triterpenoid from glyptopetalum sclerocarpum
glyyunnanprosapogenin D: from roots of glycyrrhiza yunnanensis
gm4 antibody: antibodies produced by clones of cells such as those isolated after hybridization of activated b lymphocytes with neoplastic cells; amino acid
gma12 protein, S pombe: gene from schizosaccharomyces pombe, when transfered to saccharomyces cerevisiae transfers galactose to form gal alpha 1,2-man1-o-ser/thr; forms n- and o-glycans
gnaphaliin A: isolated from gnaphalium liebmannii with tracheal smooth muscle relaxant properties
gnaphaliin B: isolated from gnaphalium liebmannii with tracheal smooth muscle relaxant properties
gnapholide: a guaiac-dimer from pulicaria gnaphalodes (asteraceae)
gnemonol B: stilbene oligomer from gnetum gnemon with antibacterial activity against vancomycin-resistant enterococci and methicillin-resistant staphylococcus aureus
gnetifolin A: from gnetum parvifolium (warb.) c.y. cheng
gnetin C: has free radical scavenging activity; isolated from gnetum gnemon
gnetin E: stilbene oligomer from gnetum sp. with antibacterial activity against vancomycin-resistant enterococci and methicillin-resistant staphylococcus aureus
gnetofuran A: from a methanol-soluble extract of the stems of gnetum klossii
gnetofuran B: from a methanol-soluble extract of the stems of gnetum klossii
gnetofuran C: from a methanol-soluble extract of the stems of gnetum klossii
gnidicin: antileukemic diterpenoid ester from gnidia lamprantha
gnididin: antileukemic diterpenoid ester from gnidia lamprantha
gnidilatimonoein: isolated diterpene ester from daphne mucronata
gnidimacrin: a daphnane-type orthoester diterpene similar in structure to phorbols; antileukemic; found in gnidia, stellera, pimelea
gniditrin: antileukemic diterpenoid ester from gnidia lamprantha; for structure see card of gnididin
gnu protein, Drosophila: is essential in the cell cycle transition from meiosis to mitosis; amino acid ; refseq nm_140469
goblet cell silencer inhibitor: a silencer inhibitor confers specific expression of intestinal trefoil factor in goble cell lines; has been sequenced
gol protein, Drosophila: a 32 kda developmental gene product from d. melanogaster; amino acid sequence given in first source; refseq nm_166705
gold tetrachloride, acid: used in root canal therapy; rn given refers to (sp-4-1)
golgin-84, rat: forms tether with casp, involved in the intra-golgi transport; a golgin
golimumab: golimumab plus mtx effectively reduces the signs and symptoms of ra and is generally well tolerated in patients with an inadequate response to mtx
golmaenone: diketopiperazine alkaloid from the marine-derived fungus aspergillus sp.
golodirsen: synthetic antisense oligonucleotide designed to cause skipping of abnormal exons in the synthesis of the dystrophin gene and that is used to treat duchenne muscular dystrophy
golvesin protein, Dictyostelium: a 64-kda protein from dictyostelium cells; genbank u89350
gombapyrone A: produced by streptomyces griseoruber acta 3662
gombapyrone B: produced by streptomyces griseoruber acta 3662
gombapyrone C: produced by streptomyces griseoruber acta 3662
gombapyrone D: produced by streptomyces griseoruber acta 3662
gombaspiroketal A: from the sponge clathria gombawuiensis
gombaspiroketal B: from the sponge clathria gombawuiensis
gombaspiroketal C: from the sponge clathria gombawuiensis
gomenol: solution of niaouli oil; contains cineol, terpineol; limonene & pinene
gomesin: isolated from the hemocytes of the spider acanthoscurria gomesiana; amino acid
gomisin M2: lignan extract from fruit schisandra chinensis (turcz). baill. (schisandraceae; s. chinensis) has antiallergic effects: inhibit mast cell activation and human immunodeficiency virus present study shows it has anti-inflammatory effects
gomphoside: rn given refers to (2alpha(2s,3s,4r,6r),3beta,5alpha)-isomer
gomphrenin I: a red pigment with nsaid and antioxidant activities; isolated from the fruit of basella alba
gonadotropin I beta subunit, Fundulus: amino acid sequence given in first source; from killifish, f. heteroclitus
gonadotropin I beta-subunit, bass: isolated from striped bass, morone saxatilis; amino acid
gonadotropin I, Katsuwonus: from bonito katsuwonus plelamis pituitary glands; homologous to chum salmon gonadotropins; mw 39 kda; amino acid sequence given in first source
gonadotropin I, tuna: isolated from the tuna thunnus obesus; amino acid
gonadotropin II alpha subunit, catfish: amino acid sequence given in first source; isolated from the african catfish clarias gariepinus
gonadotropin II beta subunit, Fundulus: amino acid sequence given in first source; from killifish, f. heteroclitus
gonadotropin II beta subunit, bass: isolated from striped bass, morone saxatilis; amino acid
gonadotropin II beta subunit, catfish: amino acid sequence given in first source; isolated from african catfish clarias gariepinus
gonadotropin II, Katsuwonus: from bonito katsuwonus plelamis pituitary glands; homologous to chum salmon gonadotropins; mw 30 kda; amino acid sequence given in first source
gonadotropin II, tuna: isolated from the tuna thunnus obesus; amino acid
gonadotropin releasing hormone associated peptide: 56 amino acid sequence peptides given in first source for human & rat; joined to lhrh by 3 amino acid processing site
gonadotropin- pituitary, beta-subunit I, salmon: enhances estradiol production in salmonid ovarian follicles in vitro & stimulates gonad growth in juvenile rainbow trout in vivo; glycoprotein; 113-amino acid residues; amino acid sequence given in first source
gonadotropin-associated-peptide releasing enzyme: acts on pre-pro-gonadotropin releasing hormone to produce a sequence of 56 amino acids called gonadotropin releasing hormone associated peptide (gap). probably a metalloproteinase or serine proteinase
gonadotropin-inhibitory hormone, Coturnix japonica: isolated from the japanese quail
goniodomin A: polyether macrolide; metabolite of goniodoma pseudogoniaulax
goniolandrene-A: has antineoplastic activity; isolated from goniothalamus macrophyllus
goniolandrene-B: has antineoplastic activity; isolated from goniothalamus macrophyllus
goniomedine B: isolated from the stem bark of gonioma malagasy; exhibited moderate activity against plasmodium falciparum
goniopectenoside B: a minor asterosaponin from starfish goniopecten with antifouling activity
goniothalamicin: linear polyketide isolated from extracts of the stembark of goniothalamus giganteus
goniotriocin: bioactive annonaceous acetogenins from goniothalamus giganteus
goniotriol: from goniothalamus giganteus; has shown some activity in the brine shrimp lethality test and the potato disc assay
gonobactin: low mw iron-reactive siderophore from neisseria gonorrhoeae which enables parasite to compete successfully with host's iron-sequestering mechanisms
gonococcal growth inhibitor protein, Staphylococcus haemolyticus: antigonococcal produced by staphylococcus haemolyticus; mw 2,565; contains 25 amino acids
gonococcal surface lectin-adhesin: mw 440kd with 65kd subunit on sds-page; present in all n gonorrhoeae strains tested; omp with vaccine potential
gonyauline: from gonyaulax polyedra; shortens the period of the circadian clock in the unicellular alga
goralatide: from fetal calf bone marrow; exerts a high inhibitory activity on the proliferation of hematopoietic pluripotent stem cells
gordonic acid: isolated from the mixed culture of two gram-positive bacteria, gordonia sp. kmc005 and streptomyces tendae kmc006
gordonin: a glycosylated lipopeptide cell wall component of a smooth variant of gordona hydrophobica; amino acid sequence given in first source
gordox: drugs having as their active substance aprotinin (trasylol, gordox); gordox and contrycal are distinct molecules that both act as kallikrenin protease inhibitors
gorei-san: composed of alismatis rhizoma, atractylodis lanceae rhizoma, polyporus, hoelen, cinnamomum bark; inhibits urinary calcium oxalate crystallization
gorgostan-5,25-dien-3'-ol: from the red sea soft coral lobophytum lobophytum
gosha-jinki-gan: a kampo medicine; composed of rehmanniae radix, achyranthis radix, corni fructus, dioscorea rhizoma, plantaginis semen, alismatis rhizoma, hoelen, moutan cortex, cinnamoni cortex, aconiti calefactum tuber in ratio 5:3:3:3:3:3:3:3:1:1 mixed with 19 parts lactose
goshuyu-to: from evodia fruit; chinese traditional medicine; has body temperature retaining effect
gossypetin 8-O-lyxopyranoside: from the aerial part of orostachys japonicus (crassulaceae)
gossypin: do not confuse with gossypin(e) which is synonym for choline
gossyplure: natural sex pheromone of pink bollworm moth; a mixture of equal amounts of z,z & z,e isomers of the above
gostatin: amino acid produced by streptomyces sumanensis; time-dependent inhibitor of aspartate transaminase
gp105 envelope protein, Human immunodeficiency virus 2: a 105 kda glycoprotein; derived from a precursor of gp140
gp12 protein, Enterobacteria phage T4: a short-tail fiber composed of a structural protein which is a trimer; 527 amino acid residues, mw 56.124 kda; amino acid sequence has been determined
gp125 envelope protein, Human immunodeficiency virus 2: immunoreactive glycoprotein encoded by the hiv-2 env gene
gp130 (783-800), myristoyl-: inhibits interaction of gp130 with hck
gp130 envelope protein, Human immunodeficiency virus: has been sequenced; from hiv-2(ben) isolate
gp14 protein, equine herpesvirus 1: amino acid sequence of protein from equine herpesvirus 1 given in first source
gp140 envelope protein, Human immunodeficiency virus 1: an oligomeric form of hiv-1(iiib) envelope protein; contains all of gp120 and the entire gp41 ectodomain
gp140 envelope protein, Human immunodeficiency virus 2: immunoreactive glycoprotein encoded by the hiv-2 env gene
gp15-400 protein, Brugia pahangi: surface-associated molecule; member of the nematode polyprotein allergens; has been sequenced; genbank x68190
gp160 processing protease: converts hiv gp160 to gp120 and gp41, cleaving between arg511 and ala512
gp17 protein, Enterobacteria phage P1: shows homology with proteins of the t4 lysozyme family; amino acid sequence given in first source; genbank x87673
gp17 protein, Enterobacteria phage T4: required to translocate phage t4 dna into the head; t4 dna packaging proteins gp16 and gp17 act as t4 terminase; amino acid sequence given in first source
gp18 protein, Borna disease virus: purified from infected rat brain; amino acid sequence given in first source
gp20 protein, bacteriophage T4: vertex capsid protein responsible for the initiation of head assembly, dna packaging & binding with the tail connector; mw 60.9 kda; contains 524 amino acids; amino acid sequence given in first source
gp20 sialoglycoprotein, human: a capacitated sperm surface protein & homolog of leukocyte cd52 antigen
gp21 morphogenetic proteinase, phage T4: involved in delivery of encapsidated fusion proteins into bacteria
gp22 protein, Nicotiana tabacum: related to pathogenesis-related protein pr5; partial amino acid sequence given in first source
gp23 protein, Bacteriophage T4: amino acid sequence given in first source
gp24 protein, Bacteriophage BF23: a minor tail protein; amino acid sequence given in first source; genbank d12824
gp240 glycoprotein, human: present on the surface of more than 80% of human melanoma cell lines & fresh biopsy specimens; significant therapeutic and diagnostic utility
gp25 protein, Bacteriophage BF23: a major tail protein; amino acid sequence given in first source; genbank d12824
gp30 envelope transmembrane protein, Bovine leukemia virus: consists of 214 amino acids with two potential glycosylation sites
gp32 protein, Enterobacteria phage T4: binds single-stranded nucleic acids regardless of sequence & functions in t4 dna replication by binding cooperatively to single-stranded dna
gp34 protein, cytomegalovirus: a glycoprotein that forms complex with folded class i mhc molecules; amino acid
gp38P protein, mouse: a glomerular podoplanin homolog; amino acid
gp41 (665-683), HIV: 665-683 fragment of the hiv fusion glycoprotein 41
gp50 protein, Schistosoma: responsible for serological cross-reactivity with trichinella spiralis; amino acid sequence has been determined
gp52 protein, spleen focus-forming virus: a transport-defective leukemogenic envelope glycoprotein; has been sequenced
gp53, bovine viral diarrhea virus: nucleotide sequence given in first source; mw 51-8 kda; do not confuse with lysosomal protein gp53
gp55 protein, Aspergillus fumigatus: major allergenic component of aspergillus fumigatus; a 55 kd glycosylated protein; has been isolated and characterized; aa composition, sugar composition, and n-terminal aa sequence given in first source; do not confuse with 18 kd allergen asp f i
gp57-67 binding protein: a surface glycoprotein involved in measles virus binding; mw 57-67 kda depending on the cell type; its degree of down-regulation is correlated with the amount of measles virus haemagglutinin expressed by infected cells; has been sequenced
gp62 protein, bacteriophage T4: a component of the clamp loader complex; a t4 dna polymerase accessory protein; has been sequenced
gp71 protein, Mycobacteriophage L5: confers immunity to l5 superinfection; 183 amino acid residues; amino acid sequence given in first source
gp85 protein, rat: 85 kda glycoprotein (gp85) is a marker of the avesicular zone, a thin part of pulmonary endothelial cells separating alveolar and vascular compartments and lacking vesicles
gp88 protein, Influenzavirus C: influenza virus glycoprotein antigenic determinant
gp91ds-tat protein, chimeric: a chimeric cell-permeant peptide that inhibits nad(p)h oxidase; includes a 9-amino acid peptide derived from hiv-coat protein (tat) linked to a 9-amino acid sequence of gp91phox
gpA protein, Enterobacteria phage P2: overexpression is lethal to host cell; mw about 78 kda; 761 amino acid residues; amino acid sequence given in first source
gpFI protein, Bacteriophage lambda: promotes the incorporation of the prohead to the dna-terminase complex; similar in structure and properties to the e. coli ns proteins; mw 21,800 da; isoelectric point 4.1; sequence known
gpFII protein, bacteriophage lambda: bacteriophage lambda head-tail joining protein; 117 amino acid residues; mw about 13 kda; amino acid
gpUL132 protein, human cytomegalovirus: refseq yp_081567
gpa-3 protein, C elegans: two g protein alpha subunits gpa-3 and odr-3, expressed in ash and in different, nonoverlapping sets of sensory neurons, are necessary for the response to quinine
gpat4 protein, Drosophila: refseq nm_001299890.1
gpc-1 protein, C elegans: g-protein gamma subunit of the nematode c.elegans is involved in taste adaptation; has been sequenced
gpc-2 protein, C elegans: g-protein gamma subunit of the nematode c.elegans is involved in taste adaptation; has been sequenced
gph protein, Ixodes scapularis: an immunodominant antigen in engorged tick salivary glands; genbank af209911
gpm6ab protein, zebrafish: a proteolipid protein; refseq nm_214687
gporf2 protein, bacteriophage phiadh: from lactobacillus gasseri temperate phage phiadh; mw 14 kda; amino acid
gracilioether A: antimalarial metabolite from the marine sponge agelas gracilis
gracilioether B: antimalarial metabolite from the marine sponge agelas gracilis
gracilioether C: antimalarial metabolite from the marine sponge agelas gracilis
gracillin: spirostan glycoside from tamus communis; rn given refers to (3beta,25r)-isomer
gradex: polymer preparation resulting from formation of covalent bonds between gramicidin s and dextran; has antimicrobial activity
grainin 1 protein, Entamoeba histolytica: is a calcium-binding proteins and a protozoan proteins isolated from entamoeba histolytica; amino acid ; genbank af085196
grainin 2 protein, Entamoeba histolytica: is a calcium-binding proteins and a protozoan proteins isolated from entamoeba histolytica; amino acid ; genbank af082530
grambin: a thrombin-like enzyme; from the venom of trimeresurus gramineus; mw 45 kda; partial amino acid sequence given in first source
gramesol: mixture of gramicidin, anesthesin(benzocaine), menthol & ethyl alcohol; russian drug
gramicidin-S-synthetase 2: enzyme i activates proline, valine, ornithine & leucine; enzyme ii is phenylalanine activating & racemizing
graminelysin I: a snake-venom-derived metalloproteinase that induces apoptosis of human endothelial cells; amino acid
grammistin: toxin from mucus of soapfishes; rn given refers to grammistin
granatin B: a carbonic anhydrase inhibitor isolated from punica granatum; do not confuse with granaticin b
granatumin H: from the seeds of a krishna mangrove, xylocarpus granatum
granatumin I: from the seeds of a krishna mangrove, xylocarpus granatum
grandibracteoside A: triterpenoid saponin anthranilate from albizia grandibracteata leaves
grandibracteoside B: triterpenoid saponin anthranilate from albizia grandibracteata leaves
grandibracteoside C: triterpenoid saponin anthranilate from albizia grandibracteata leaves
grandifloroside 11-methyl ester: from the dried leaves, flowers, and twigs of adina racemosa
grandisin: ; a lignan isolated from the bark of cryptocarya crassinervia; rn given refers to ((2alpha,3beta,4alpha,5beta)-(-))-isomer
grandisoic acid: from weevil, plum curculio, conotrachelus nenuphar (coleoptera: curculionidae), an important pest of fruit
grandisol: major component of the four synergistic cpds of male boll weevil pheromone
grandivitin: a matrix metalloproteinase 9 inhibitor; isolated from ferulago macrocarpa
grandlure: four components of boll weevil pheromone; cis-2-iso-propenyl-1-methylcyclobutaneethanol; 3,3-dimethyl-cyclohexaneethanol; 3,3-dimethyl-cyclohexaneacetaldehyde (z) & (e)
granulatamide A: cytotoxic tryptamine derivative from the soft coral eunicella granulata
granulatamide B: cytotoxic tryptamine derivative from the soft coral eunicella granulata
granule-bound starch synthase I: sequences of 9 alleles from potato have been determined
granulin A, Ciona savignyi: from ciona savignyi; mw 5931 da
granulocyte colony-stimulating factor, Tyr(1)-Tyr(3)-: recombinant protein in which thr(1) & leu(3) are replaced by tyr; used for receptor binding assays
granulocyte inhibitory protein II: inhibits the biological activity of polymorphonuclear cells; from plasma of uremic patients; mw 9500 da; amino acid sequence has been determined
granulocyte inhibitory protein, human: a 23 kda protein overexpressed in chronic renal disease; regulates expression of interleukin 6 & interleukin 8; amino acid sequence has been determined
granulocyte receptor 1, mouse: member of the ly6 family; do not confuse with gr-1 protein, mouse
granulocyte-macrophage colony-stimulating factor, Arg(21)-: glutamate replaced by arginine at position 21
granuloma initiation factor: a cyclosporin a binding protein with isomerase activity; consists of 16, 20 & 23 kd proteins; amino acid sequence of 20 kd protein shows homology to mouse cyclophilin; do not confuse with growth inhibitory factor
granuloma protein, mouse: mw 55,000; from mouse; fully protects mice against infection by l. monocytogenes & activates mouse peritoneal cells against lewis carcinoma cells
granulosa cell high-mobility group-box protein-1, rat: hmg-box transcriptional regulator strongly expressed in ovarian granulosa cells and functions as a regulator of follicular development; genbank ab096685
graphisquinone: from the cultured lichen mycobionts of graphis desquamescens
graphiumins: from the marine-derived fungus graphium sp. opmf00224.
grapiprant: a potent and selective prostaglandin ep4 receptor antagonist with antihyperalgesic properties; cyclooxygenase inhibitors
grass pollen extract, alum-adsorbed: pollen extract prepared from grass such as timothy, orchard grass, perennial ryegrass, sweet vernalgrass, or meadow fescue; usually it is extracted with pyridine and alum-precipitated to provide allergen extract for medical use
grasshopper ketone: a phytotoxin isolated from oryza sativa awaakamai
grasshopper ketone 3-O-primveroside: from sinocrassula indica
grassypeptolide: a marine cyanobacterial cytotoxin from lyngbya confervoides
grassypeptolide A: a marine cyanobacterial cytotoxin from lyngbya confervoides
grassypeptolide B: a marine cyanobacterial cytotoxin from lyngbya confervoides
grassypeptolide C: a marine cyanobacterial cytotoxin from lyngbya confervoides
grassypeptolide D: from a red sea leptolyngbya cyanobacterium
grassypeptolide E: from a red sea leptolyngbya cyanobacterium
grassystatin A: isolated from a cyanobacterium, identified as lyngbya cf.
grassystatin D: antineoplastic, potent aspartic protease inhibitor from marine cyanobacteria
grassystatin E: antineoplastic, potent aspartic protease inhibitor from marine cyanobacteria
grassystatin F: antineoplastic, potent aspartic protease inhibitor from marine cyanobacteria
gratioside: a cucurbitacin glycoside from gratiola officinalis; ; rn given for (beta-d)-isomer
grau protein, Drosophila: the grauzone transcript is present in ovaries and at later developmental stages; necessary for high-level activation of cortex transcription; amino acid ; genbank af208016
gravidin: inhibits release of arachidonic acid from human decidual cells; purified from amniotic fluid; mw 58-60kda; inhibits phospholipase a2
gravohormone combination: preparation produced in russia & bulgaria to shorten the period from calving to impregnation & raise the conception rate & the fertility in cows
grayanotoxin I: rn given refers to (3beta,6beta,14r)-isomer
grayanotoxin III: from leaves of leucothoe grayana (ericaceae); rn refers to (3beta,6beta,14r)-isomer
grayanotoxin IV: grayanane diterpenoid from aerial parts of rhododendron decorum
grayanotoxin XXI: isolated from the leaves of rhododendron decorum (ericaceae)
grdn-1 protein, C elegans: refseq nm_001269887.1
green fluorescent protein, Aequorea victoria: a 238 residue (27 kd) protein, from the aequorea victoria jellyfish, that emits green light (peak at 509 nm) when excited with ultraviolet rays
green tea bioflavonoid, zinc ascorbate-containing toothpaste: green tea bioflavonoid/zinc ascorbate-containing dentifrice
greigite: component of magnetosomes (membrane-bound magnetic crystals) in bacteria that causes them to be oriented in magnetic fields; used as biomarkers
grem1a protein, zebrafish: a bone morphogenetic protein inhibitor; genbank ay427782
grenadamide: isolated from the marine cyanobacterium lyngbya majuscula
grey-lethal protein, mouse: gl protein function is absolutely required for osteoclast and melanocyte maturation and function
gricertine: brain phospholipids containing the following: lysophosphatidyl choline 6%; sphingomyelin 12%; phosphatidyl choline 47%; phosphatidyl ethanolamine,-serine 30%; phosphatidic acid 5%
griffipavixanthone: xanthine oxidase inhibitor from garcinia esculenta twigs
griffithin: has antineoplastic activity; isolated from streptocaulon griffithii
griffithsin protein, Griffithsia: naturally occurring algae protein that inhibits hiv, herpes simplex virus (hsv-2), and other pathogens; genbank ay744143
griffonianone D: an isoflavone with anti-inflammatory activity from the root bark of millettia griffoniana
griffonilide: rn given for (6alpha,7beta,7abeta)-isomer; isolated from the roots of semiaquilegia adoxoides
griffonin: obtained from the dried powdered roots of griffonia simplificolia; possible use as an anti-sickling drug for sickle cell disease crisis; rn given refers to (4r-(1z,4alpha,5beta,6alpha))-isomer, known as lithospermoside
grifolan LE: a 1-3 glucan with single unit 1-6 branches every third residue; has antineoplastic activity; isolated from grifola frondosa; carbohydrate
grifolic acid: isolated from the fungus albatrellus confluens; induces cell death in mouse osteosarcoma tumors
grifolinone C: a meroterpenoid pigment, isolated as red powder from the fruiting bodies of the basidiomycete albatrellus confluens
grifolisin, Grifola frondosa: a pepstatin-insensitive carboxyl proteinase & member of the sedolisin family produced by the fruiting bodies of fungus grifola frondosa (maitake mushroom); amino acid sequence known
grifonin-1 peptide, Griffithsia: a 121-mer peptide that inhibits hiv-1 entry; isolated from a red alga
grim protein, Drosophila: induces apoptosis of neurons; isolated from drosophila; amino acid
grincamycin B: angucycline glycosides isolated from actinomycete streptomyces strains
grip210 protein, Xenopus: xgrip - xenopus gamma ring protein; a member of the gamma-tubulin ring complex; genbank xla291606
griselimycin: an antitubercular agent; isolated from streptomyces
grisemycin: angucyclinone from a marine-derived streptomyces sp.
griseulin: from streptomyces; rn refers to (e,e)-isomer
griseusrazin A: from the marine-derived bacterium streptomyces griseus that suppresses inflammation
grk protein, Drosophila: amino acid sequence given in first source; may activate torpedo/der during oogenesis; essential for defining the anterior-posterior and dorsal-ventral axes of the egg; during oogenesis this signaling pathway instructs follicle cells to follow a dorsal pathway of development rather than the default ventral pathway; homologous to transforming growth factor alpha; refseq nm_057220
grn protein, Drosophila: a drosophila melanogaster gata factor; genbank d50542
gro protein, Drosophila: required for neurogenesis, segmentation, and sex determination in drosophila; a transcriptional corepressor recruited to specific target promoters by hairy-related basic-helix-loop-helix (bhlh) proteins; amino acid sequence known; refseq nm_170254
groEL protein, Cyanidium caldarium: from cyanidium caldarium; amino acid sequence given in first source
groES protein, Mycobacterium tuberculosis: amino acid sequence given in first source; immunoreactive antigen of the vaccine strain mycobacterium bovis
grossularine 1: ; from the tunicate dendrodoa grossularia; rn from chem abst. index guide 1986
grossularine 2: ; rn from chem abst. index guide 1986; from the tunicate dendrodoa grossularia
group 5 allergens, Ambrosia: amino acid sequence given in first source; from giant ragweed (ambrosia trifida) pollen
group B protective surface protein, S agalactiae: isolated from group b streptococci; genbank aj133114
group-specific protease: a serine protease, obtained from rat small intestine, which preferentially inactivates the apo forms of certain pyridoxal phosphate requiring enzymes
growth arrest-specific protein 6: gas6 is a member of the vitamin k-dependent proteins related to protein s; a variety of receptors bind gas6 as a ligand
growth blocking peptide, Apanteles kariyai: a 25-mer peptide from parasitized insect hemolymph; amino acid sequence has been determined
growth differentiation factor 7: the closely related gdf5, gdf6 & gdf7 define a new subgroup of factors related to known bone- & cartilage inducing molecules, the bone morphogenetic proteins (bmps)
growth factor-activatable Na-H exchanger NHE-1: amiloride sensitive; a ubiquitous mammalian protein that is involved in the regulation of intracellular ph & cell volume; partial amino acid sequence given in first source
growth hormone releasing hexapeptide: synthetic hexapeptide that acts on pituitary to specifically release growth hormone
growth hormone releasing hexapeptide, Lys(6), thionated: synthetic hexapeptide; amide oxygen is replaced by sulfur
growth hormone releasing hormone-related peptide: a second peptide encoded by ghrh; the 30 amino acid c-terminal peptide of the ghrh precursor protein; abundant in testicular germ cells; specifically activates sertoli cell expression of stem cell factor; partial amino acid sequence given in first source
growth hormone type I, Salmo salar: amino acid sequence given in first source; 210 amino acid residues; from atlantic salmon (salmo salar) liver
growth hormone, Lymnaea stagnalis: produced by neurosecretory light green cells of cerebral ganglia
growth inhibitor (faba bean): condensed tannin in hulls of faba beans reduces growth in chicks
growth inhibitory proteins: membrane protein which arrests cell growth in the 3t3 cell plasma membrane; see also record for fibroblast growth factor; do not use /antag
growth promoting activity receptor: a chick growth promoting factor with low homology to mammalian ciliary neurotrophic factor; has multiple roles in neuronal development; amino acid sequence given in first source; genbank z48168
growth-associated retinal protein 48: 48-kd acidic protein from goldfish retina during optic nerve regeneration; protein 68-70 has mw of 68-70 kda and is apparently the same as gap-48
grp1a protein, Sinapis alba: a clock-controlled protein in long-day plant sinapis alba; amino acid sequence given in first source; genbank l31374
grp2a protein, Sinapis alba: a clock-controlled protein in long-day plant sinapis alba; amino acid sequence given in first source; genbank l31377
grp3 protein, Hordeum vulgare: glycine-rich protein isolated from barley hordeum vulgare; amino acid ; genbank z48624
grsT protein, Bacillus brevis: amino acid sequence given in first source; first identified in bacillus brevis and homolog then discovered in bacillus subtilis; exhibits a significant degree of homology to vertebrate fatty acid thioesterases (ec 3.1.2.- )
grxcr1b protein, zebrafish: refseq xm_021480742
gsb-n protein, Drosophila: a pax group iii protein isolated from drosophila; encodes a product with specific rna polymerase ii transcription factor activity involved in segment polarity determination int the embryo; amino acid ; do not confuse with gooseberry protein (gsb), a distal protein also from drosophila
gsiB protein, Bacillus subtilis: from bacillus subtilis; amino acid sequence given in first source; product of glucose starvation-inducible gene gsib; involved in adaptive response to nutrient deprivation other than sporulation; induced in response to glucose starvation, also by heat shock, salt and oxidative stress; glucose deprivation induces sporulation; genbank x56680
gskt protein, Drosophila: acquired an essential role in male fertility; amino acid ; refseq nm_170547
gt protein, Drosophila: transcription factors suggests that it acts as short-range repressor, interfering with the activity of enhancer or promoter elements 50 to 100 bp away; refseq nm_080310
gtcA protein, Listeria monocytogenes: encoded by a serogroup-specific gene; isolated from listeria monocytogenes; 88% homologous to listeria innocua gtca gene; amino acid ; genbank af072894
gtk kinase: gtk - gastrointestinal-associated tyrosine kinase; a fyn-related kinase involved in growth/differentiation of gut columnar epithelial cells
gu-jing-mai-si-ha: may be useful in treating premature ejaculation
guadinomic acid: a type iii secretion system inhibitor; isolated from streptomyces
guadinomine A: a type iii secretion system inhibitor; isolated from streptomyces
guadinomine B: a type iii secretion system inhibitor; isolated from streptomyces
guadinomine C: a type iii secretion system inhibitor; isolated from streptomyces
guadinomine D: a type iii secretion system inhibitor; isolated from streptomyces
guadinomine E: a type iii secretion system inhibitor; isolated from streptomyces
guai-3-en-10alpha-ol: from the stems of kadsura heteroclita
guai-6-en-10-ol, isopimara-7,15-dien-2-ol: terpene from leaves of guarea macrophylla (meliaceae)
guaia-1(10),11-diene: from the essential oil of fruits of peucedanum tauricum bieb
guaiacol peroxidase: many isoenzymes are involved in plant growth and development; guaiacol peroxidase was see myeloperoxidase 1989-1993
guaiacylglycerol 3-O-(6-O-p-coumaroyl)glucopyranoside: isolated from dracocephalum forrestii
guaiacylglycerol 3-O-(6-O-p-hydroxybenzoyl)glucopyranoside: isolated from dracocephalum forrestii
guaiacylglycerol beta-O-4-guaiacyl ether dehydrogenase: nad+ required; forms the corresponding ketone at the alpha carbon of the glycerol side chain
guajaphenone A: has antibacterial activity; isolated from psidium guajava
guajavanoic acid: pentacyclic triterpenoid from the leaves of psidium guajava (myrtaceae)
gualamycin: an acaricide effective against mites; isolated from streptomyces sp. nk11687
gualou xiebai baijiutang: consists of frutus trichosanthis, allium macrostemon, and white spirit (ethanol)
guamamide: cytotoxin from a species of marine cyanobacterium belonging to the genus symploca that was collected in guam
guamecycline: rn given refers to (4s-(4alpha,4aalpha,5aalpha,6beta,12aalpha))-isomer
guamerin: a cysteine-rich polypeptide of 57 amino acid residues; from a korean native leech hirudo nipponia; a human leukocyte and porcine pancreatic elastase-specific inhibitor; has 51% sequence homology with hirustasin; amino acid sequence given in first source
guan xin II: decoction used for treatment of coronary artery disease; five component herbs: salviae miltiorrhizae radix, chuanxiong rhizome, paeniae radix rubra, carthami flos and dalbergiae odoriferea lignum
guan-xin-ning: used to treat heart disease; consists of radix salvia miltiorrhiza and rhizoma ligusticum chuanxiong
guancydine: minor descriptor (72-85); on-line & index medicus search guanidines (72-85)
guangomide A: from the cytotoxic extract obtained from the saltwater culture of a sponge-derived fungus
guangomide B: from the cytotoxic extract obtained from the saltwater culture of a sponge-derived fungus
guanidine 1,5-diazabicyclo(5.3.0)decane: structure given
guanidine 1,5-diazabicyclo(5.4.0)undecane: structure given
guanidine biboric acid adduct: a boron compound as an antitumour agent against ehrlich ascites carcinoma in mice
guanidine diphosphate-arabinopyranose: a precursor of d-ara(p) in leishmania major lipophosphoglycan
guanidino propyl piperazine: anti-plaque agent; rn given refers to dimethanesulfonate
guanidinoacetase: hydrolyzes the guanidino group to guanidine & urea
guanidinoacetate kinase: catalyzes the phosphorylation of urinary guanidinoacetic acid in the presence of atp to phosphoguanidinoacetate
guanidinobenzoate esterase: cleaves both 4-nitrophenyl-p-guanidinobenzoate & 4-methylumbelliferyl-p-guanidinobenzoate with the release of nitrophenol & methylumbelliferone, respectively
guanidinooxypropylamine: from wisteris florabunda seeds & seedlings of canavalia gladiata
guanidinosuccinic acid: a metabolite in uremia; metabolic product of amino acid metabolism; rn given refers to (l)-isomer
guanine nucleotide binding protein (G protein), beta polypeptide 3, mouse: refseq nm_013530
guanjiekang: is formed by five medicinal herbs including astragali radix, aconiti lateralis radix praeparaia, glycyrrhizae radix et rhizoma, corydalis rhizoma and paeoniae radix alba was used for the treatment of rheumatoid arthritis
guanosine 3',5'-polyphosphate synthetases: involved in stringent/relaxed responses of amino acid-starved bacteria; do not confuse with rela which is the p65 subunit of nf-kappa b
guanosine 5'-(trihydrogen diphosphate)-N-(4-azidophenyl)-2-phosphoramido-3-(4-hydroxy-3-iodophenyl)propionamide monoanhydride: used for identification of the gtp-binding domain in beta-tubulin
guanosine 5'-triphosphate 3'-diphosphate pyrophosphorylase: yields pyrophosphate + pppg
guanosine diphosphate glucose: acts as a source of glucose for cellulose synthesis in some plants; minor descriptor (75-83); on-line & index medicus search guanosine diphosphate sugars (75-83); rn given refers to (alpha-d)-isomer
guanosine pentaphosphate synthetase: also possesses polynucleotide phosphorylase activity; amino acid sequence given in first source; genbank u19858
guanosine phosphotransferase: from eimeria tenella; uses several phosphate donors: acetyl phosphate >atp >utp >phosphoribosyl pyrophosphate to form gmp
guanosine-3',5'-bis(diphosphate) 3'-pyrophosphatase: catalyzes breakdown of guanosine tetraphosphate into guanosine diphosphate and pyrophosphate
guanosine-5'-triphosphate, 3'-diphosphate pyrophosphatase: catalyzes the hydrolysis of guanosine 5'-triphosphate, 3'-diphosphate to yield guanosine 5'-diphosphate, 3'-diphosphate & orthophosphate; from e coli; also hydrolyzes other guanosine 5'-triphosphate derivatives with at least one unsubstituted phosphate group on the 3'-position, but not gtp, atp or adenosine 5'-triphosphate, 3'-diphosphate
guanoxan: was mh 1976-92 (see under guanidines 1976-90); use guanidines to search guanoxan 1976-92; antihypertensive agent similar in its mechanism of action to guanethidine; may cause liver damage
guanxin V: contains 6 herbs: codonopsis radix, ophiopogon japonicus, schizandra chinensis fructus, rehmannia radix praeparata, radix salviae, and radix paeoniae rubra
guanxin shutong: used to treat myocardial ischemia; consists of fructus choerospondiatis, radix salviae miltiorrhizae, flos caryophylli, bomeolum, and concretio silicea bambusae
guanxin suhe wan: traditional form of honey bolus, comprising styrax, borneolumsyntheticum, olbanum, radix aristolochiae and lignum santali albi
guanyeliaoine I: from polygonum perforliatum l. (chinese name "guanyeliao", berberidaceae)
guanyeliaoine II: from polygonum perforliatum l. (chinese name "guanyeliao", berberidaceae)
guanylate cyclase 1: mutations associated with leber's congenital amaurosis; refseq nm_000180
guanylate cyclase-inhibitory protein, Xenopus: do not confuse with transcription factor gcip
guanylin: from rat jejunum; contains 15 amino acids; activator of intestinal guanylate cyclase; stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins; amino acid sequence given in first source; genbank z73607 (pig)
guanylin 99-115: a small human peptide hormone with two disulfide bonds; amino acid
guanylin, European eel: isolated from anguilla anguilla; genbank aj301672 (short form) and aj301673 (long form)
guanylyl cyclase-G, mouse: a testis-enriched receptor guanylyl cyclase
guanylyl cyclase-activating protein, bovine: 25-kda protein isolated from bovine rod and cone cells; genbank x95352
guanylyltransferase: guanylation of heterologous rna containing 2 or 3 phosphate or g(5')pppn at their 5' terminal; transfer of a gmp moiety from gtp to the 5' end of an rna molecule containing at least two terminal phosphate
guar gum: bulk-forming appetite depressant; water-soluble component is guaran; see also record for locust bean gum (supercol); ctmans gene codes for the mannan synthase and alpha-galactosyltransferase adds galactosyl residues
guar gum-degrading enzyme: a 62 kda gum-degrading enzyme from bacillus circulans; also degrades cellulose & amylose; partial amino acid sequence given in first source
guar meal protein, Cyamopsis tetragonoloba: fraction other than guar gum after milling of guar beans; chemically different from guar gum, containing 35-40% protein and less than 5% galactomannan
guarana powder: from the seeds of guarana; 1 gram guarana powder contains 2.16 mg theobromine, 1.10 mg theophylline, and 36.78 mg caffeine
guatteguamerine: a neuroprotective agent with antioxidant properties; isolated from bark of guatteria gaumer; ; rn given refers to (r-(r*,r*))-isomer
guatteriopsiscine: 7,7-dimethylaporphine alkaloid from the stem of guatteriopsis friesiana
guayulin A: sesquiterpene cinnamic acid ester potent contact allergen in mexican rubber plant, guayule (parthenium argentatum)
guhong: has anti-inflammatory activity; used to treat cerebrovascular diseases; consists of aceglutamide and safflower aqueous extract
gui-zhi-jia-shao-yao-tang: tcm mixture of peony root, cinnamon bark, jujube fruit, glycyrrhiza root, ginger in ratio 6:4:4:2:1
guiachrysine: quaternary indole alkaloid from the stem bark of strychnos guianensis
guibi-tang: used to treat a number of ailments, such as to treat amnesia, fatigue, forgetfulness, anorexia, anemia, insomnia, palpitation, and neurosis; consists of angelica gigas, dimocarpus longan, panax ginseng, zizyphus jujuba, polygala tenuifolia, astragalus membranaceus, poria cocos, atractylodes japonica, zizyphus jujube, aucklandia lappa, glycyrrhiza uralensis, and zingiber officinale
guieranone A: a naphthyl butenone from the leaves of guiera senegalensis with antifungal activity
guignardic acid: phytotoxic secondary metabolite from the grape black rot fungus, guignardia bidwellii
guignardone D: from endophytic fungus a1 of scyphiphora hydrophyllacea
guignardone E: from endophytic fungus a1 of scyphiphora hydrophyllacea
guilingji: composed of ginseng radix et rhizome rubra (panax ginseng c.a.mey)
guineensine: an acyl-coa: cholesterol acyltransferase inhibitor, from the fruits of piper longum; structure in first sourc
guipi: a radioprotective agent consisting of astragalus membranaceus (fisch.) bge., radix glycyrrhizae (liquid-fried), radix gineng, radix angelicae sinensis , rhizoma atractylodis, semen ziziphi spinosae , rhizoma atractylodis macrocephalae, poria, radix aucklandiae, radix polygalae, and arillus longan
guizhi decoction: contains cinnamon bark, peony root, glycyrrhiza root, ginger and jujube fruit; used for resisting bacteria, virus, pain and allergy, reducing the blood sugar, increasing the cardiac muscle blood flux, improving the digestion and transmition of stomach and intestines, and easing up spasmus; can also prevent the arthritis, and cure the cervical spondylosis and chronic pancreatitis
guizhi-fuling: a traditional chinese medical (kampo) formulation composed of five kinds of medicinal plants, cinnamomum cassia blume (cinnamomi cortex), paeonia lactiflora pall. (peonies radix), paeonia suffruticosa andrews (moutan cortex), prunus persica batsch (persicae semen), and poria cocos wolf (hoelen); may be beneficial for the treatment of brain ischemia-reperfusion injury partly due to its anti-inflammatory properties
guizhi-shaoyao-zhimu decoction: has been shown effective in the treatment of diabetic peripheral neuropathy
gukulenin A: cytotoxic terpene from the marine sponge phorbas gukulensis
gukulenin B: cytotoxic terpene from the marine sponge phorbas gukulensis
gulypyrone A: produced by diaporthe gulyae, a potential mycoherbicide for saffron thistle (carthamus lanatus)
gulypyrone B: produced by diaporthe gulyae, a potential mycoherbicide for saffron thistle (carthamus lanatus)
gum combretum: isolated from combretum nigrans; rhamnose and uronic acid moieties are located within polysaccharide chains and are non-terminal, unlike in gum arabic; has been used as an adulterant
gummiferaoside A: cytotoxic triterpenoid saponin of albizia gummifera from the madagascar rain forest
gummiferaoside B: cytotoxic triterpenoid saponin of albizia gummifera from the madagascar rain forest
gummiferaoside C: cytotoxic triterpenoid saponin of albizia gummifera from the madagascar rain forest
gung-gui-tang: a korean herbal drug derived from angelicae radix and cnidii rhizoma; has been used to treat autoimmune disease
gunnilactam A: from the mycelial culture of the entomogenous fungus paecilomyces gunnii
gunnilactam B: from the mycelial culture of the entomogenous fungus paecilomyces gunnii
gunnilactam C: from the mycelial culture of the entomogenous fungus paecilomyces gunnii
gus protein, Drosophila: a spry-domain and socs-box containing developmental protein; essential for posterior localization of vasa (vas) protein; has been sequenced; refseq nm_001259211
gushudan: used to treat osteoporosis; consists of herba epimedii, fructus cnidii, rhizoma drynariae, and radix salviae miltiorrhizae
gusperimus: synthesized by chemical modification of spergualin; in combination with cyclosporin a prevents diabetes in predisposed nod mice; ; rn given refers to (-)-isomer trihydrochloride
gussurobin: isolated from the venom of gloydius ussuriensis; amino acid
gut PLY, Torpedo marmorata: isolated from intestinal extracts of an electric ray torpedo marmorata; modelled
guttiferone F: a prenylated benzophenone from allanblackia stuhlmanii
guttiferone I: prenylated benzophenone from garcinia humilis as a liver x receptor ligand
guttiferone K: antiproliferative compound of rheedia calcicola from the madagascar rain forest
guttiferone L: antiproliferative compound of rheedia calcicola from the madagascar rain forest
guttiferone O: mapkapk-2 inhibitor from garcinia solomonensis
guttiferone P: mapkapk-2 inhibitor from garcinia solomonensis
guvacoline: nootropic agent from areca nut (areca catechu l.)
guyonianin E: cytotoxic to hek293 cells; isolated from euphorbia guyoniana
guyonianin F: cytotoxic to hek293 cells; isolated from euphorbia guyoniana
gwennpaullone: inhibits cyclin-dependent protein kinases, glycogen synthase kinase-3, and malate dehydrogenase
gycomoside I: ; isolated from the aerial part of gynostemma compressum x
gyeongshingangjeehwan: anti-obesity drug containing extracts of the four herbs: liriope platyphylla, platycodon grandiflorum, schisandra chinensis, ephedra sinica
gylongiposide I: a triterpenoid saponin from the aerial parts of gynostemma longipes c.y. wu.
gymnangiamid: a cytotoxic pentapeptide from the marine hydroid gymnangium regae
gymnastatin F: cytostatic metabolite from the sponge-derived fungus gymnascella dankaliensis
gymnastatin G: cytostatic metabolite from the sponge-derived fungus gymnascella dankaliensis
gymnastatin H: cytostatic metabolite from the sponge-derived fungus gymnascella dankaliensis
gymnastatin Q: cytostatic metabolite from the sponge-derived fungus gymnascella dankaliensis
gymnastatin R: cytostatic metabolite from the sponge-derived fungus gymnascella dankaliensis
gymnasterkoreayne F: inhibits osteoclast differentiation; isolated from gymnaster koraiensis
gymnemaside VI: isolated from the methanol extract of the aerial parts of gynostemma pentaphyllum
gymnemoside A: a triterpene glucoside isolated from leaves of gymnema sylvestre; ; inhibits glucose absorption
gymnemoside B: a pentacyclic triterpene saponin isolated from the leaves of gymnema sylvestre; ; inhibits glucose absorption
gymnin protein, Gymnocladus chinensis: also has both antifungal and antineoplastic activity
gymnoascolide C: aromatic butenolide from an australian isolate of the soil ascomycete gymnoascus reessii
gymnochrome E: cytotoxic; from a deep-water crinoid, holopus rangii
gymnochrome F: cytotoxic; from a deep-water crinoid, holopus rangii
gymnocladus saponin E: from the fruit of gymnocladus chinensis baill
gymnocladus saponin F2: from the fruit of gymnocladus chinensis baill
gymnoconjugatin A: from an australian isolate of the soil ascomycete gymnoascus reessii
gymnoconjugatin B: from an australian isolate of the soil ascomycete gymnoascus reessii
gymnodimine: a spiro-imine algal toxin; a neurotoxic shellfish poison produced by karenia selliformis (formerly gymnodinium selliforme) and related species
gymnodimine A: macrocyclic imine phycotoxin produced by the dinoflagelate karenia selliformis
gymnodimine C: lipophilic toxin produced by the marine dinoflagellates karenia selliformis and alexandrium ostenfeldii
gymnodimine D: lipophilic toxin produced by the marine dinoflagellates karenia selliformis and alexandrium ostenfeldii
gymnopalyne A: chloropropynyl-isocoumarin antibiotic from cultures of the basidiomycete gymnopus sp.
gymnopalyne B: chloropropynyl-isocoumarin antibiotic from cultures of the basidiomycete gymnopus sp.
gymnopilin 1: activates phospholipase c; isolated from gymnopilus junonius
gymnothelignan V: lignan subtype isolated from gymnotheca chinensis decne (g. chinensis)
gynecophoral canal protein, 86-kDa: expressed in the gynecophoral canal of male worms; mw 79-86 kda; amino acid sequence given in first source; genbank u47862
gynosaponin TN-1: produced from the enzymatic conversion of gyp xlvi by naringinase in gynostamma pentaphallum; has cytotoxic effect on hepatoma cell lines