NLK-NML/MeSH-CZ-2025-notes huggingface dataset:
caffeine synthase: catalyzes last two steps of caffeine synthesis, converting 7-methylxanthine to theobromine and then to caffeine; 20 amino acid n-terminal
caffeine, sodium benzoate drug combination: rn given refers to an equal mixture of caffeine and benzoate; merck, 9th ed, #1628 reference for caffeine sodium benzoate
caffeine:ubiquinone oxidoreductase, Pseudomonas: catalyzes the conversion of caffeine, ubiquinone, and water to trimethylurate and ubiquinol; used for rapid testing for caffeine in mother's milk, beverages, and pharmaceuticals
caffeoyl shikimate esterase, Arabidopsis: catalyzes the hydrolysis of caffeoyl shikimate to yield shikimate and caffeate
caffeoyl-CoA O-methyltransferase: catalyzes the methylation of caffeoyl-coa to form trans-feruloyl-coa; also accepts with low affinity various other caffeic esters as substrates; do not confuse with ec 2.1.1.68 which acts on caffeic acid; has been sequenced; genbank l22203 (stellaria longipes)
caffeoylcalleryanin: lipoxygenase inhibitor from cuspidaria pulchra
caffeoylmalic acid: from extracts of chelidonium majus & corydalis lutea
caffeoylxanthiazonoside: anti-allergic, anti-inflammatory and analgesic from fruits of xanthium strumarium
cagA protein, Helicobacter pylori: amino acid sequence given in first source; a 120-128-kda protein associated with peptic ulcer disease and cytotoxin production by helicobacter pylori; may be necessary for the transcription, folding, export or function of the cytotoxin; genbank l11714
cagF protein, Helicobacter pylori: associated with peptic ulcer disease and cytotoxin production by helicobacter pylori
caged AIP: a highly specific inhibitor of calmodulin-dependent protein kinase ii
cahuitamycin A protein, Streptomyces gandocaensis: inhibits biofilm formation by acinetobacter baumannii
cahuitamycin B protein, Streptomyces gandocaensis: inhibits biofilm formation by acinetobacter baumannii
cahuitamycin C protein, Streptomyces gandocaensis: inhibits biofilm formation by acinetobacter baumannii
caiD protein, E coli: homologous to enoyl hydratases and isomerases; converts d(+)-carnitine to l(-)-carnitine
caihu-dayuan-yin: contains bupleuri radix, glycyrrhizae radix, and ponciri fructus
cairicoside E: has antineoplastic activity; isolated from ipomoea cairica
cairomycin A: yields val & asp on hydrolysis; from streptomyces sp. as-c-19; rn given refers to the (2ll)-isomer
cairomycin C: yields lys, gly, val, leu & asp on hydrolysis; from streptomyces sp. strain as-c-19
caissarine A: dibromotyrosine-derived alkaloid from the brazilian endemic marine sponge aplysina caissara
caissarine B: dibromotyrosine-derived alkaloid from the brazilian endemic marine sponge aplysina caissara
caissarolysin I, Bunodosoma caissarum: hemolytic toxin isolated from a brazilian sea anemone; partial amino acid
cajaminose: extract from the seeds of cajanus cajan; has effect on gelation and oxygen affinity of sickle cell hemoglobin
cajanonic acid A: prenylated stilbene derivative extracted from the leaves of pigeon pea (cajanus cajan (l) millsp)
cajucarinolide: ; a clerodane diterpene isolated from the cortices of the tree croton cajucara
cajuput oil: isolated from melaleuca leucadendron l. (myrtaceae)
calabadion 1: reverses benzylisoquinoline and steroidal neuromuscular-blocking agent effects
calamistrin A: a monotetrahydrofuran acetogenin from root of uvaria calamistrata
calamistrin B: a monotetrahydrofuran acetogenin from root of uvaria calamistrata
calanolide A: nsc 661122 and costatolide are isomers; a novel hiv-inhibitory class of coumarin derivatives from the tropical rainforest tree, calophyllum lanigerum (clusiaceae)
calanolide B: ; one of a novel class of hiv-inhibiting coumarins from the tropical rainforest tree, calophyllum lanigerum
calarene: has larvicidal activity against mosquitoes; isolated from kadsura heteroclita
calcaratarin D: a cytotoxic bis-labdanic diterpenoid from alpinia calcarata
calcaratarin E: a cytotoxic bis-labdanic diterpenoid from alpinia calcarata
calcein AM: a non-fluorescent compound cleaved to a fluorescent compound by non-specific intracellular esterases
calcemic fraction A: biologically active; hypercalcemic & bone resortive peptide which is the biosynthetic precursor of parathyroid hormone
calceolarioside A: ; isolated from calceolaria hypericina; induces platelet aggregation
calcicludin: 60 amino acid peptide from venom of dendroaspis angusticeps; potent blocker of high-threshold ca+ channels with a high affinity for l-type channels in cerebellar granule neurons; has homology with kunitz-type protease inhibitor family; partial amino acid sequence given in first source
calciferin: serum factor stimulating cathepsin d release from erythrocytes or ghosts
calcification-associated peptide-1, crayfish: from crayfish, procambarus clarkii; amino acid
calcineurin B-like protein 1, Arabidopsis: the calcium sensor cbl1 integrates plant responses to abiotic stresses; has been sequenced
calcineurin Balpha2: derived from calcineurin balpha gene in testis; produced through alternative utilization of a testis-specific promoter; amino acid sequence given in first source; genbank d14425 & d14568
calcineurin-AF: synthetic peptide fragment inhibitor of ca2+-dependent phosphatase calcineurin
calciseptine: amino acid sequence given in first source; specific blocker of the l-type calcium channel; from black mamba venom
calcitermin peptide, human: a putative c-terminal cleavage fragment of calgranulin c; an antimicrobial peptide isolated from human airway secretions; amino acid
calcitionin(15-19) peptide, human: no refseq available; peptide fragment of calcitonin
calcitonin gene related peptide (19-37): acts as inhibitor of calcitonin gene-related peptide
calcitonin gene-related peptide (19-37), t-butyl-Cys(18)-: amino acid sequence given in first source; arg is replaced by cys at position 18; a synthetic antigenic fragment
calcitonin gene-related peptide (23-37): acts as inhibitor of calcitonin gene-related peptide
calcitonin gene-related peptide (8-37): cpd is cgrp receptor antagonist, but is an agonist for calcitonin receptor
calcitonin gene-related peptide (8-37), propionyllysyl(24)-: a radioactive tracer
calcium acetate: a principal compound used as phosphate binders in patients with chronic renal failure; used like sevelamer
calcium alginate, glucuronic acid drug combination: calcium alginate enriched with glucuronic acid
calcium binding protein p22, rat: n-myristoylated protein similar to calcineurin b; refseq nm_024139
calcium carbonate Biocoral: a natural resorbable coralline material made of calcium carbonate for bone replacement grafts
calcium channel cocalization factor-1, C elegans: a neuronal transmembrane protein that localizes to the endoplasmic reticulum
calcium channel, l type beta2c subunit, rat: a functional type of beta subunit from the rat heart; has been sequenced
calcium citrate malate: a stable powder containing ca to citric to malic ratio of 4:2:3
calcium dependent sulfhydryl protease: hydrolyzes actin binding protein; enzyme from platelets
calcium hydroxide, calcium chloride, potassium chloride, sodium bicarbonate, sodium chloride drug combination: calcium hydroxide preparation with nacl, kcl, cacl2 & nahco3
calcium hydroxide, carboxymethylcellulose, dried blood plasma, zinc oxide drug combination: contains zinc oxide, calcium hydroxide, dried blood plasma & carboxymethylcellulose
calcium magnesium carbonate: mineral recommended by lay periodicals as a desirable source of calcium & magnesium, but found to be also a source of potentially toxic heavy metals
calcium magnesium dependent endodeoxyribonuclease: similar in action but different from dnase i
calcium pantothenate, carboxymethylcellulose, glycerin, silver sulfameter, xylene drug combination: an ointment preparation
calcium phosphate, dibasic, anhydrous: molecular formula cahpo(4), dcpa=dicalcium phosphate anhydrous; don't confuse with dichloropropionanilide which also is called dcpa; mw=136.06; has greater surface area and lower ph than dcpd (dicalcium phosphate dihydrate); occurs in nature as monetite; an intermediate in preparing hydroxyapatite
calcium phosphate, dibasic, dihydrate: molecular formula cahpo(4)-2(h2o)
calcium phosphate-DNA precipitate: activates chromosomal human genes normally stimulated by interferon
calcium response transcription factor 1, rat: salicylate alters the expression of carf1 in the cochlea; has been sequenced
calcium salicylate: the anti-cancer effectiveness of calcium salicylate has been investigated on human ht-1080 fibrosarcoma cell lines. the results here demonstrate evidence for approximately 25% apoptosis after treatment with calcium salicylate
calcium sucrose phosphate: maintains ph of dental plaque above critical level for enamel demineralization; mixture of calcium salts of phosphoric acid esters of sucrose & inorganic calcium orthophosphate
calcium sulfide: rn given refers to parent cpd; see also record for lime sulfur (calcium polysulfide)
calcium tungstate aluminum sodalite: sodalites are beta-cages consisting of alo4 (or sio4 in some cases) tetrahedra; in this case, the alo4 tetrahedra-formed cages accomodate calcium and tungstate guest ions
calcium-binding protein (brain): calcium-binding protein from bovine brain; mw 21,000; peptide mapping & amino acid composition analysis given in first source; different from calmodulin & other calcium-binding proteins
calcium-binding protein 1, Dictyostelium discoideum: a developmentally-regulated protein from d. discoideum; 156 amino acids, mw 17,740 da; amino acid sequence given in first source; genbank x82784; do not confuse with liver calcium-binding & centromere-binding proteins
calcium-binding protein 2, Dictyostelium: ef-hand protein from dictyostelium discoideum; amino acid ; do not confuse with liver calcium-binding & centromere-binding proteins
calcium-binding protein p6, human: member of s100 protein family; amino acid sequence known
calcium-binding protein, 57-kDa: a developmentally-expressed cytosolic, trophoblast-specific protein; amino acid
calcium-binding protein, Arabidopsis: a 21.7-kda protein that shares 66% identity with arabidopsis calmodulin; amino acid sequence given in first source
calcium-binding protein, Echinococcus: a 300 kda protein associated with calcareous corpuscles in e. granulosus; amino acid sequence given in first source; genbank l33817
calcium-binding protein, Entamoeba histolytica: amino acid sequence given in first source; isolated from entamoeba histolytica
calcium-binding protein, Tetrahymena: a member of the calmodulin family; from the cilium and cell body of tetrahymena; amino acid sequence given in first source; composed of 102 amino acid residues; mw 11 kda
calcium-binding protein-1 (liver): a hepatic microsomal intralumenal protein; partial amino acid sequence given in first source; do not confuse with centromere-binding protein & calcium-binding protein 1 from dictyostelium
calcium-calmodulin-activated histone 3 arginine kinase: from nuclear extracts of dividing & quiescent rat heart endothelial cells; represents a new class of ca-cam-dependent kinases which phosphorylate arg
calcium-dependent protease I: atypical cysteine protease which is inactivated by some serine protease inhibitors; isolated from allomyces arbuscula
calcium-dependent protein kinase: mw 51,000; requires ca; not stimulated by calmodulin, phospholipids or diacylglycerol; phosphorylates casein & histones forming primarily phosphoserine & phosphothreonine, respectively
calcium-dependent protein kinase 2, Arabidopsis thaliana: refseq nm_111902
calcium-dependent protein kinase 20, Arabidopsis thaliana: refseq nm_129449
calcium-dependent protein kinase, rice: a protein kinase that endows rice plants with cold- and salt-stress tolerance functions in vascular bundles; has been sequenced
calcium-dependent protein kinase-1, Plasmodium falciparum: involved in motility
calcium-enriched mixture cement: a hydrophilic endodontic cement. the major components of the cement powder are calcium oxide (cao), sulfur trioxide (so3), phosphorous pentoxide (p2o5), and silicon oxide (sio2). it is sometimes referred to as "a new endodontic cement" or nec
calcium-eugenol cement: consists of calcium oxide, titanium dioxide, bismuth oxide, eugenol, resina cholophonii, benzoylacetone
calcium-hydrogen antiporters: provides mechanism to keep intracellular ca concentration low; electroneutral; is heat-labile & insensitive to low concentrations of ruthenium red & lanthanides
calcium-independent processing protease: converts hiv-1 gp160 precursor to gp120 and gp41
calcium-independent protein kinase C: induces apoptosis in thymocytes; npkc-delta & -epsilon are isoforms; see also npkctheta protein
calcium-like peptide CALP1: a type of ca(2+) channel blocker that targets ca(2+) sensors and prevents ca(2+)-mediated apoptosis; amino acid
calcium-like peptide CALP3: a type of ca(2+) channel blocker that targets ca(2+) sensors and prevents ca(2+)-mediated apoptosis; amino acid
calcium-regulated heat-stable protein 28: expressed primarily in pancreas and other digestive tissues; amino acid
calcyclin-associated protein 50: amino acid sequence given in first source; a 50 kda new member of the calcium/phospholipid-binding proteins of the annexin family; from rabbit lung
calcyon: a 24-kilodalton single transmembrane d1 dopamine receptor interacting protein that regulates dual signaling; has been sequenced; genbank af225903
caldarchaeol: isolated from the deep-sea archaeon methanococcus jannaschii
caldariellaquinone: isol from caldariella acidophila; extremely thermophilic acidophilic bacterium
caldecrin: isolated from porcine pancreas; has chymotrypsin-like protease activity; decreased serum calcium in mice; may act by inhibiting parathyroid hormone; mw 28 kda; has been sequenced
calditoglycerocaldarchaeol: ; do not confuse with glycerol dialkyl nonitol tetraethyl ether, also known as gdnt
caldolase: a chelator-insensitive extracellular serine proteinase from thermus tok(3)
caldolysin: heat stable extracellular metal-chelator-sensitive lytic protease from thermus t-351
caldopentamine: from cells of extreme thermophile, thermus thermophilus, grown at 80 degrees celcius
caledol: has antifungal activity; isolated from calophyllum caledonicum
caleflone: isolated from blossoms of pot marigold, calendula officinalis; used therapeutically on experimental hepatitis in rats
caleosin protein, Sesamum indicum: found in oil bodies of plant seeds; amino acid ; genbank x89891
calerythrin protein, Saccharopolyspora erythraea: isolated from saccharopolyspora erythraea; has been sequenced
calfactant: a lung surfactant extract from new born calves containing 35 mg/ml phospholipid & 2% surfactant-associated proteins b & c (wt/wt)
calfluxin: involved in the influx of ca into mitochondria of the albumen gland of the snail lymnaea stagnalis
calglandulin, Bothrops insularis: an ef-hand protein from the venom glands of bothrops insularis snake; genbank af545856
calgranulin B, bovine: mw 17.3 kda; substrate of protein kinase c; member of the s100 family; partial amino acid
calicheamicin T: calicheamicin derivative that lacks the b-c-d rings of the carbohydrate tail of calicheamicin gamma(1); almost identical to esperamicin d; cleaves dna in double-stranded fashion & nonselectively
calicheamicin gamma(1)I: ; isolated from micromonospora echinospora sp. calichensis; acts as a dna double-stranded cleaving agent
calicheamicin theta(1)I: an enediyene antibiotic, suppresses growth and dissemination of liver metastases in malignant diseases
calicheamicin thetaII: is a member of the enediyne class of antitumor antibiotics that bind to dna and induce apoptosis
calichearubicin B: a synthetic hybrid molecule containing the anthraquinone chromophore of (da) and the carbohydrate domain of calicheamicin epsilon
califin: biologically active peptides from atrial gland of aplysia californica; consist of 36-residue subunit bound by a disulfide bond to an 18-residue subunit; have possible role as pheromones
caligulin protein, Bos taurus: a calcium-binding protein isolated from bovine brain; molecular weight of 28000 d
calin: from saliva of hirudo medicinalis, mw 65 kda; amino acid sequence known
calix(4)arene: a cyclophane consisting of four phenolic units linked by methylene groups
callatostatin: from bowfly calliphora vomitoria; contain 8-16 amino acids; have sequence homology to cockroach allatostatins; inhibit juvenile hormone production; amino acid sequence given in first source
callicarpaquinone A: from the stem bark of callicarpa maingayi
callicarpaquinone B: from the stem bark of callicarpa maingayi
callicoside C: hepatoprotective compound from the leaves of callicarpa nudiflora
callimplexen A: from the red sea sponge callyspongia aff. implexa
calliphorin protein, Calliphora vicina: protein from blowfly larva hemolymph
callisulfakinin II: a sulfakinin from the blowfly calliphora vomitoria; a tetradecapeptide; amino acid sequence given in first source
callitachykinin I: a myotropic tachykinin-like peptide from blowfly, calliphora vomitoria; amino acid sequence given in first source
callitachykinin II: a myotropic tachykinin-like peptide from blowfly, calliphora vomitoria; amino acid sequence given in first source
calliterpenone: a stereo-isomer of abbeokutone from mentha arvensis
callophycin A: cytotoxic; from callophycus oppositifolius
callyaerin A: antitubercular from the marine sponge callyspongia aerizusa
callyaerin B: antitubercular from the marine sponge callyspongia aerizusa
callyazepin: nitrogenous macrocycle from a callyspongia sp. sponge
callynormine A: from the kenyan marine sponge callyspongia abnormis
callyspongamide A: cytotoxic polyacetylenic amide from red sea sponge callyspongia fistularis
callyspongenol A: cytotoxic c22-polyacetylenic alcohol from a red sea sponge, callyspongia sp.
callyspongenol B: cytotoxic c22-polyacetylenic alcohol from a red sea sponge, callyspongia sp.
callyspongenol C: cytotoxic c22-polyacetylenic alcohol from a red sea sponge, callyspongia sp.
callyspongiamide A: sterol o-acyltransferase (soat) inhibitor isolated from marine sponge callyspongia sp
callyspongiamide B: sterol o-acyltransferase (soat) inhibitor isolated from marine sponge callyspongia sp
callysponginol sulfate A: an mt1-mmp inhibitor isolated from the marine sponge callyspongia truncata
callyspongynic acid: a polyacetylenic acid isolated from the marine sponge callyspongia truncata
calmedin: mw 300kda; membrane protein form brain mediating the inhibition of inositol 1,4,5-triphosphate receptor binding by calcium
calmegin: a testis-specific endoplasmic reticulum-associated protein expressed during mammalian spermatogenesis; 101 kda
calmidazolium: powerful inhibitor of or red blood cell ca++-atpase & ca++ transport into inside-out red blood cell vesicles; rn refers to chloride; ; an antagonist of calmodulin
calmodulin (1-77): binds cyclic nucleotide phosphodiesterase but does not interact with most of the other calmodulin-binding proteins present in brain extracts
calmodulin (78-148): carboxyl-terminal half fragment of calmodulin
calmodulin acceptor protein 60: mw 60kda; from rat liver cytosol
calmodulin converting enzyme: removes carboxyl terminal lysine from calmodulin at ph 6
calmodulin dependent protein kinase II phosphatase: dephosphorylates and regulates camkii; mw 54-65 kda
calmodulin, aminotyrosine(138)-: tyr-138 converted to amino-tyr
calmodulin, aminotyrosine(99)-: tyr-99 converted to amino-tyr
calmodulin-binding protein 25 kDa, Arabidopsis: functions as a negative regulator of osmotic stress tolerance in arabidopsis thaliana seedlings; genbank ay531115
calmodulin-dependent protein kinase V: widely distributed in various tissues, involved in calcium-regulated processes; from rat brain; may exist in 40 & 41 kda isoforms; amino acid sequence has been determined
calmyonemin: analog of algal centrin; mol wt 23 kda; isoelectric point 4.9; occurs in contractile myonemes of eudiplodinium maggii; partial amino acid sequence has been determined
calnexin-like melanosomal protein p90: a membrane-bound protein; associated with melanosomal membrane and endoplasmic reticulum; has been sequenced
calobin: isolated from the korean viper agkistrodon caliginosus; amino acid ; genbank104841
calonyctin A-2b: ; one of two components of calonyctin a; see dc-2d for other component
calonyctin A-2d: ; one of two components of calonyctin; see dc-2b record for other component
calopolyanolide C: calopolyanolide c & d are pyranocoumarin diastereoisomers from the seeds of calophyllum polyanthum
caloporoside: a salicylic acid derivative; contains a mannopyranosyl and a mannonic acid moiety; from fermentations of caloporus dichrous
calopusin A: has antineoplastic activity; isolated from boletus pseudocalopus
calopusin B: has antineoplastic activity; isolated from boletus pseudocalopus
calopusin C: has antineoplastic activity; isolated from boletus pseudocalopus
caloteysmannic acid: antineoplastic from the stem bark of calophyllum teysmannii
calotropain-FI: isolated from calotropis gigantea latex, broad ph optimum, inhibited by sulfhydryl reagents
calotropain-FII: isolated from calotropis gigantea latex, broad ph optimum, inhibited by sulfhydryl reagents
calotropin DI: from latex of madar plants, calotropis gigantea; cysteine protease; do not confuse with calotropin in chemline, which is not an enzyme
calotropin DII: from latex of madar plants, calotropis gigantea; cysteine protease; do not confuse with calotropin in chemline which is not an enzyme
calotroposide A: ; oxypregnane-oligoglycoside from the root of calotropis gigantea
calotroposide B: ; oxypregnane-oligoglycoside from the root of calotropis gigantea
caloxanthin 3'-beta-D-glucoside: displayed potent o(2) quenching activity
caloxin 1A1: a synthetic plasma membrane ca(2+)-pump inhibitor; amino acid seqeunce known
caloxin 1c2: an engineered selective inhibitor of plasma membrane ca(2 )-pump isoform 4
caloxin 3A1: inhibits pmca pump selectively with higher affinity than caloxin 2a1; amino acid
calpain 10: calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodelling and signal tranduction; genetic variation in capn10 is associated with type 2 diabetes mellitus
calpain C, Drosophila: must be catalytically inactive, having mutated active site residues but is otherwise structurally similar to the other known fly calpains; revealed strong expression in the salivary glands; refseq nm_132890
calpain Lp82: a lens-specific, calcium-activated isozyme from the calpain super family of cysteine proteases; lp85 is an isoenzyme of lp82; amino acid ; genbank af091998
calpain activator: an inner plasma membrane protein isolated from erythrocytes; activates calpain at low calcium ion concentrations; amino acid
calpain inhibitor 2: inhibits degradation of 3-hydroxy-3-methylglutaryl-coenzyme a reductase and some other cysteine proteinases
calpain inhibitors: bovine heart protein; mw 145,000; from many cells & tissues with mw 48,000-400,000 depending on tissue, species or isolation procedures
calpain p94: amino acid sequence given in first source; a subunit of calpain which is expressed only in skeletal muscle
calpastat: comprised of cell-penetrating signal sequence of kaposi's fibroblast growth factor fused to calpain-inhibiting consensus sequence of calpastatin
calpastatin: large mol wt, heat-stable calpain inhibitor; not based on sequestering ca++ from medium, but binding to calpain does require ca++
calphostin D: ; isolated form cladosporium cladosporioides; see also record for calphostin complex
calphostin I: isolated from cladosporium cladosporioides; see also record for calphostin complex
calphostin complex: ; isolated from cladosporium cladosporioides; complex of five closely related components, calphostin a,b,c,d & i; see also records for specifics
calpinactam: isolated from the culture broth of mortierella alpina fki-4905
calponin homolog protein, Schistosoma japonicum: isolated from sjp adult worm , contains a full length cdna encoding a 38.3 kda protein; amino acid ; genbank af040386
calreticulin transacetylase, human: involved in the activation of human platelet nitrite reductase by polyphenolic acetates
calreticulin transacetylase, rat: the results bear evidence for the activation of tsmc nos by ac and their effectiveness to enhance no of airway cells may be expected to find useful applications in respiratory diseases
calsensin protein, Hirudinea: expressed in a subset of peripheral leech neurons fasciculating in a single axon tract; 83 amino acids, mw 9.1 kda; genbank u22066
calstorin protein, rat: abundant in rat brain; mw 54 kda; n-terminal amino acid sequence given in first source
caltractin: ubiquitous centrosome-associated protein of eukaryotic cells of diverse origins, including algae, protozoa & mammals; amino acid sequence given in first source; homology with calmodulin & yeast cdc31 protein; member of ef-hand superfamily; genbank u92973
caltubin, Lymnaea stagnalis: a molluscan tubulin-interacting protein that promotes axonal growth and attenuates axonal degeneration of rodent neurons
calycanthine: the principal alkaloid of the plant family calycanthaceae; rn given refers to (4bs)-(4balpha,5alpha,10balpha,11alpha)-isomer
calyciphylline A: a hexacyclic alkaloid from daphniphyllum calycinum
calyciphylline B: a hexacyclic alkaloid from daphniphyllum calycinum
calycopterin: an immunoinhibitory compound from the extract of dracocephalum kotschyi
calycopterone: a flavone attached to benzopyran; isolated from calycopteris floribunda (combretaceae)
calycosin 7-O-(alpha-D-glucopyranosyl(1-4))-beta-D-glucopyranoside: from shenqi fuzheng injection
calycosin-7-O-beta-D-glucoside: from radix astragali
calycosin-7-O-glucopyranoside: from radix astragali
calyculaglycoside D: from the caribbean gorgonian octocoral eunicea sp.
calyculaglycoside E: from the caribbean gorgonian octocoral eunicea sp.
calyculin A: rn given refers to (5s-(5alpha(2r*(1s*,3s*,4s*,5r*,6r*,7e,9e,11e,13z),3r*),7beta(e(s*)),*beta,9alpha))-isomer
calyculin B: rn for (2r,3r,5r,7s,8s,9r)-2-[(1s,3s,4s,5r,6r,7e,9e,11e,13e)-14-cyano-3,5-dihydroxy-1-methoxy-4,6,8,9,13-pentamethyl-7,9,11,13-tetradecatetraen-1-yl]-7-[(2e)-3-{2-[(2s)-4-{[(2s,3s,4s)-4-(dimethylamino)-2,3-d ihydroxy-5-methoxypentanoyl]amino}-2-butanyl]-1,3-oxazol-4-yl}-2-propen-1-yl]-9-hydroxy-4,4,8-trimethyl-1,6-dioxaspiro[4.5]dec-3-yl dihydrogen phosphate isomer; a standard for evaluating serine-threonine proteinase inhibitors
calyculinamide A: from the marine sponge theonella swinhoei
calystegin: substances produced by plant roots that act as nutritional mediators; found in calystegia sepium, convolvulus arvensis, and atropa belladonna
calystegine B(2): rn given for (2-endo,3-exo,4-endo)-isomer
calystegine B1: also inhibits beta-xylosidase; ; rn refers to (2-endo,3-exo,6-exo)-isomer
calyxamide A: cytotoxic; from the marine sponge discodermia calyx
calyxamide B: cytotoxic; from the marine sponge discodermia calyx
calyxamine A: a piperidine alkaloid from sponge calyx podatypa
calyxamine B: a piperidine alkaloid from sponge calyx podatypa
calyxin I: a diarylheptanoid from the seeds of alpinia blepharocalt
camazepam: was heading 1977-94 (see under benzodiazepine tranquilizers 1977-90); use temazepam to search camazepam 1978-94 & benzodiazepine tranquilizers 1977-90; a benzodiazepine used as a minor tranquilizer; it is the dimethyl carbamate salt of temazepam
cambodianol: a cytotoxic homoisoflavonoid from dracaena cambodiana
camel thorn distillate: its therapeutic effect may be due to the flavanones (alhagitin and alhagidin) that are present in alhagi pseudalhagi
cameleon 2.1 protein, Drosophila: no refseq available
camellianin A: flavonoid glycoside isolated from bai-shui-cha
camellianin B: flavonoid glycoside isolated from bai-shui-cha
camelliaside A: ; a flavonol triglycoside isolated from seeds of camellia sinensis
camelliaside B: ; a flavonol triglycoside isolated from seeds of camellia sinensis
camelliaside C: a flavonol diglycoside; isolated from the seeds of camellia sinensis
camelliatannin F: isolated from the leaves and flower buds of camellia japonica
camelliatannin G: isolated from the leaves and flower buds of camellia japonica
camelliatannin H: isolated from the leaves and flower buds of camellia japonica
camellioside E: from the flower buds of camellia japonica; has melanogenesis inhibitory and fibroblast proliferation accelerating effects
camellioside F: from the flower buds of camellia japonica; has melanogenesis inhibitory and fibroblast proliferation accelerating effects
camelysin: the cell envelope-bound metalloprotease (camelysin) from bacillus cereus is a possible pathgenic factor; mw 19 kda; partial amino acid
camelysin, Bacillus cereus: a surface zinc-binding metalloproteinase from bacillus cereus; genbank aj514407
caminoside B: antimicrobial glycolipid from the marine sponge caminus sphaeroconia
caminoside C: antimicrobial glycolipid from the marine sponge caminus sphaeroconia
caminoside D: antimicrobial glycolipid from the marine sponge caminus sphaeroconia
camk2g2 protein, zebrafish: refseq xm_005156904
campechic acid A: anti-invasive; from a soil-derived streptomyces
campechic acid B: anti-invasive; from a soil-derived streptomyces
campesin, Brassica campestris: a 9.4-kda antifungal peptide from seeds of the cabbage (brassica campestris)
camphor, cedar leaf oil, eucalyptus oil, menthol, myristica oil, terebinth oil, thymol drug combination: combination of camphor, menthol, terebinth oil, eucalyptus oil, cedar leaf oil, thymol & myristica oil
camphor, menthol, parachlorophenol drug combination: mixture of 35% p-chlorophenol with camphor & menthol
camphor-10-sulfonyl chloride: rn refers to (1s)-isomer
camphor-2-spirohydantoin: ; rn given refers to (1r-(1alpha,2alpha,4alpha)-isomer)
camphor-6-exo-hydroxylase: a cytochrome p-450-dependent monooxygenase that catalyzes the hydroxylation of camphor to 6-hydroxycamphor in sage and mycobacterium
camphora: a component of guanxingao, a kind of traditional chinese rubber electuary medicine which is able to either cure or guard against coronary heart disease and angina pectoris
camphorataimide B: inhibits cox-2; isolated from antrodia camphorate
camphorated parachlorophenol: rn given refers to cpd without isomeric designation; walkhoff solution is a 3% solution of camphorated parachlorophenol
camphorin protein, Cinnamomum camphora: a ribosome-inactivating protein from seeds of cinnamomum camphora; appears to be the a-chain of cinnamomin, a type 2 rip
camptothecin copper(II) complex: causes photosensitive dna cleavage & phage inactivation
camrelizumab: a humanised anti-programmed death-1 (anti pd-1) antibody
camstatin: a functionally active 25-residue fragment of pep-19's iq motif; aa seq in first source
camylofin, dipyrone drug combination: combination of camylofin & dipyrone
can protein, Drosophila: a cell type-specific homolog of a more ubiquitously expressed component of the general transcription factor tfiid; required in vivo for high level transcription of a set of stage- and tissue-specific target genes during male gametogenesis; refseq nm_080088
canakinumab: a human anti-interleukin-1beta monoclonal antibody for treatment of cryopyrin-associated periodic syndrome
canaliculus domain-specific glycoprotein gp110: amino acid sequence given in first source; mw 110 kda; from rat hepatocytes
canangafruticoside: from the leaves of cananga odorata var. odorata
canangaterpene I: from the flower buds of cananga odorata with inhibitory effects on melanogenesis
canarione: antioxidant red pigment from the lichens lethariella sernanderi, l. cashmeriana, and l. sinensis
canatoxin: toxic protein from canavalia ensiformis (jack bean) seeds; distinct from concanavalin a
canavanine hydrolase: catalyzes hydrolysis of l-canavanine at the oxygen-nitrogen bond to yield l-homoserine and hydroxyguanidine; isolated from the tobacco budworm heliothis virescens
canavaninosuccinate synthetase: aspartate + ureido homoserine + atp yields canavaninosuccinate + amp + ppi
cancer basic protein, human: extracted from tumor tissue; stimulates blood lymphocytes from patients with malignant disease, but not blood lymphocytes from healthy individuals or patients with nonmalignant disease; similar to myelin basic protein
cancer procoagulant: a factor x-activating cysteine endopeptidase from extracts of human & animal tumors & cultures of malignant cells
cancer testis antigen NXF2, human: an inducible antigen in chronic lymphocytic leukemia
cancer-recognition, immunedefense suppression, serine protease protection peptide: amino acid sequences of crispp peptides from 12 different cancers given in first source (86% - 100 % homologous)
cancer-testis antigen P1A, mouse: p1a is normally expressed only in a few tumor lines, de novo induction by 5-aza-2'-deoxycytidine augments adoptive immunotherapy in a murine tumor model
cancerocerebral antigen, human: isolated from human brain; mw 15,000; purified preparation used for radioimmunological, immunobiological assays & amino acid analysis
cancrin, Rana cancrivora: antimicrobial peptide from sea crab-eating frog; amino acid
candelalide A: a diterpenoid pyrone from fermentations of sesquicillium candelabrum as blockers of the voltage-gated potassium channel kv1.3.
candelalide B: a diterpenoid pyrone from fermentations of sesquicillium candelabrum as blockers of the voltage-gated potassium channel kv1.3.
candelalide C: a diterpenoid pyrone from fermentations of sesquicillium candelabrum as blockers of the voltage-gated potassium channel kv1.3.
candesartan cilexetil: a prodrug which is metabolized to an active form candesartan to exert its biological effects
candibirin A: a furanocoumarin dimer isolated from heracleum candicans
candidaspongiolide: a tedanolide macrolide from marine sponge, candidaspongia sp. that induced apoptosis in human cancer cells
candihexins: hexaene macrolide antibiotic found to be a complex of two component fractions, c&i hexin i & ii; c&i hexin i is active in vitro against yeasts & filamentous fungi; candihexin ii is essentially inactive
candimine: from the bulbs of hippeastrum morelianum; cytotoxic for the trichomonas vaginalis
candoxatrilat: usan lists candoxatrilat (uk-73,967) with rn 123122-54-3
canecystatin protein, sugarcane: an antifungal agent isolated from sugarcane; amino acid
canephron N: approved as a herbal medicinal product in 28 countries; coated tablet containing centaury powder (centaurii herba), lovage root powder (levistici radix) and rosemary leaf powder (rosmarini folium)
canescin A: antifungal metabolite from a new fungicolous verticillium sp.
cang er zi wan: used to treat allergies and upper respiratory problems; prepared from xanthium sibiricum
cannabichromenic acid synthase: catalyzes oxidocylization of cannabigerolic acid to cannabichromenic acid
cannabidiol (abn-cbd, (-)-4-(3-3,4-trans-p-menthadien-(1,8)-yl)olivetol): a cannabinoid compound; stimulates endothelial cell migration via a gi/go-coupled receptor distinct from cb1, cb2 or edg-1
cannabidiolic acid synthase: catalyzes the oxidocyclization of cannabigerolic acid to cannabidiolic acid without need of molecular oxygen, coenzymes, or cofactors; isolated from cannabis sativa; n-terminal amino acid sequence given in first source
cannabipiperidiethanone: an adulterant in a herbal product which contains two other known synthetic cannabinoids, jwh-122 and jwh-081
cannabistilbene II: isolated from panamanian variant of cannabis sativea; first source concludes that above cpd can either be synonym 1 or 2; further investigation is underway
cannitoxin, Oxyuranus scutellatus canni: a presynaptic neurotoxin
cannogenin thevetoside: from thevetia neriifolia; minor descriptor (75-84); on-line & index medicus search cardenolides (77-84), cardanolides (75-76); rn given refers to (3beta,5beta)-isomer
cannogenol 3-O-beta-D-galactopyranosyl-(1-4)-O-alpha-L-rhamnopyranoside: a cardenolide from the seeds of terminalia bellerica
cantalasaponin 3: a spirostanol glycoside; from solanum nigrescens
cantastim: a bacterial immunomodulatory product consisting of distinct molecules of phospholipids obtained from pseudomonas aeruginosa
cantharidin methylimide: ; rn given refers to (3aalpha,4beta,7beta,7aalpha)-isomer
canthin-6-one-1-O-xylopyranosyl-1-6-glucopyranoside: isolated from the root bark of ailanthus altissima
canthin-6-one-5-O-xylopyranosyl-1-6-glucopyranoside: isolated from the root bark of ailanthus altissima
canthinone: a type of alkaloid isolated from the picrasma quassioides plant, widely used in traditional chinese medicine for anti-inflammation and antibiosis
cantleyoside-dimethyl-acetal: isolated from pterocephalus perennis
canventol: ; inhibits tumor necrosis factor alpha release and protein isoprenylation
cap I RNA (nucleoside-2'-)methyltransferase: converts cap 0-terminated mrna to cap i-terminated mrna
cap II RNA(nucleoside-2'-)methyltransferase: converts cap i-terminated mrna to cap ii-terminated mrna
cap-1 protein, C elegans: cap1 proteins are involved in addition of actin subunits
cap32-34 protein, Dictyostelium: amino acid sequence given in first source; heterodimeric protein that contains 2 subunits
capa protein, Drosophila: drosophila gene (capability, capa) at 99d on chromosome 3r potentially encodes three neuropeptides: ganmglyafprv-amide (capa-1), asglvafprv-amide (capa-2), and tgpsassglwgprl-amide (capa-3). capa-1 and capa-2 are related to the lepidopteran hormone cardioacceleratory peptide 2b, while capa-3 is a novel member of the pheromone biosynthesis-activating neuropeptide/diapause hormone/pyrokinin family; genbank af203878
capaurine: from root tubers of stephania kwangsiensis h.s. lo; rn given refers to (s)-isomer
capillary permeability-increasing enzyme 2: increases capillary permeability; has arginine esterase and amidase activities; isolated from agkistrodon caliginosus
capilliposide J: from the whole plant of lysimachia capillipes herms1
capillolide: isolated from the soft coral sinularia capillosa collected from the south china sea
capisterone A: cycloartanone triterpene sulfate from the marine green alga penicillus capitatus
capisterone B: cycloartanone triterpene sulfate from the marine green alga penicillus capitatus
capnine: sulfonolipid found in capnocytophaga bacteria; ; see also record for capnoids
capping enzyme, Artemia salina: both m-rna guanylyltransferase & rna 5'-triphosphatase activities; consists of ec 2.7.7.50 and ec 2.1.1.56
capping enzyme, vaccinia virus: consists of ec 2.7.7.50, ec 2.1.1.56, & rna triphosphatase
capping protein beta, Drosophila: refseq nm_057657 (beta, isoform a)
caprazamycin A: an antituberculosis antibiotic; isolated from streptomyces
caprazamycin B: anti-tuberculosis lipo-nucleoside antibiotic from streptomyces sp.
caprazamycin C: an antituberculosis antibiotic; isolated from streptomyces
caprazamycin D: an antituberculosis antibiotic; isolated from streptomyces
caprazol: an antituberculosis antibiotic; isolated from streptomyces
caprenin: a randomized triglyceride primarily comprising caprylic, capric and behenic acids; a suitable replacement for cocoa butter and other confectionery fats; its reduced energy value is due to the incomplete absorption of its c20-c24 very long chain saturated fatty acids
capreomycin N-acetyltransferase: isolated from streptomyces capreolus;
caproctamine: an m1 and m3 receptor antagonist; also inhibits acetylcholinesterase
caprylic aldehyde: structure in merck index, 9th ed, #1765
caprylidene: ketogen that, when metabolized, produces the ketones beta-hydroxybutyrate and acetoacetate, which can cross the blood brain barrier
caps protein, Drosophila: contains leucine-rich repeats; isolated from drosophila; encodes a product with cell adhesion molecule activity involved in tracheal system development which is a component of the membrane; genbank af102878
capsanthin-5,6-epoxide: from the fruits of asparagus falcatus (liliaceae)
capsianoside G: induces cd4 and cdcr4 capping and colocalization
capsid protein P40, Infectious laryngotracheitis virus: vp22a is a component of the capsid core involved in the processing and packaging of progeny dna; amino acid sequence given in first source; genbank d00565; found in other viruses
capsid protein VP1, parvovirus B19: minor capsid protein; has been sequenced
capsid protein VP2, parvovirus B19: major capsid protein; has been sequenced
capsid protein VP26, herpes simplex virus type 1: component of the capsid exterior; has been sequenced
capsid protein p72, African swine fever virus: mw 72 kda; amino acid sequence given in first source; genbank u76727-8
capsid protein p88, Hv190SV: amino acid ; genbank u41345
capsid protein, Cricket paralysis virus: a small rna-containing virus isolated from field crickets; amino acid
capsid protein, San Miguel sea lion virus: amino acid sequence given in first source; from smsv serotypes 1 & 4
capsimine: from root bark of solanum capsicastrum; exhibits strong activity against liver damage induced by ccl4
capsorubin: rn given refers to (3s,3's,5r,5'r)-isomer; a carotenoid with cyclopentane rings instead of cyclohexenes;
capsular polysaccharide K1: strains of e coli that contain above cpd are leading cause of meningitis in neonates & comprise 20-30% of bacteremic e coli isolates in adults; an alpha(2-8)-n-acetylneuraminic acid polymer; see also neural cell surface antigen bsp-2 and meningococcal group b polysaccharide
capsular polysaccharide, Salmonella: used in conjunction with a protein for prevention of typhoid fever
captodiamine: captodiamine represents an interesting strategy for achieving benzodiazepine substitution with a low risk of dependence or impairment of cognitive function
capu protein, Drosophila: a drosophila protein required for dorsal-ventral and anterior-posterior patterning of the egg chamber; related to vertebrate limb deformity; amino acid sequence given in first source; refseq nm_057618
car protein, Drosophila: eye color gene in drosophila; amino acid ; refseq nm_078686
caracasine acid: an ent-3,4-seco-kaurene isolated from the plant croton micans
carallidin: an a-type trimeric proanthocyanidin from carallia brachiata; has reactive radical scavenging and xanthine oxidase inhibitory activities
carambolaflavone A: a flavonoid c-glycoside with antidiabetic properties
caramel coloring: caramel coloring is a non-sweet and dark brown form of caramel that is commercially produced by the controlled action of chemicals and heat to sugar
caramiphen edisylate: anticholinergic and antiglutamatergic; antidote against organophosphate poisoning
carapin: a pregnane x receptor activator; isolated from carapa procera, carapa guyanensis and carapa indica
carassin: tachykinin that is structurally related to neurpeptide gamma; from the brain of the goldfish; amino acid sequence given in first source
carazostatin: ; mf c20-h25-n-o: free radical scavenger; isolated from streptomyces chromofuscus dc 118
carba-1-(4-FBzlGly7)dOT: an oxytocin receptor agonist
carbacephems: group of cephalosporin antibiotics in which the sulfur atom is replaced by a carbon atom
carbamate hydrolase: from arthrobacter oxydans p52; specific for herbicides phenmedipham & desmedipham as well as 4-nitrophenylbutyrate; hydrolyzes the carbamate linkage; amino acid sequence given in first source
carbamix: used in patch testing; mixture of zinc diethyl- and zinc dibutyldithiocarbamates and diphenylguanidine
carbamothioic acid, S,S'-(2-(dimethylamino)-1,3-propanediyl) ester: rn given refers to parent cpd; padan refers to mono-hcl
carbamoyl phosphate synthase-aspartatecarbamoyl transferase complex: enzyme complex catalyzes first two steps of pyrimidine biosynthesis in neurospora(lehninger gives glutamine cp synthase in microorganisms)
carbamoyl phosphate synthetase (arginine-specific): enzyme from saccharomyces cerevisiae & neurospora crassa; involved in arginine synthesis; uses glutamine as amide-donor; consists of 2 subunits, one is glutamine-dependent, the other is ammonia-dependent
carbamoyl-phosphate synthetase (N-acetylglutamate): present in liver extracts of marine species of fish that retain high levels of urea in their tissues for osmoregulation purposes; this is carbamylphosphate synthaseiii, despite bx at ec 6.3.5.5
carbamyl phosphatidylcholine: phosphatidylcholine in which the c-1 & c-2 ester groups have been replaced by carbamyloxy functions
carbamyl plasmin A: an active enzyme with a single free nh(2)-terminal amino group(val-561); derivative of ec 3.4.21.7, fibrinolysin
carbapenam synthetase: catalyzes the cyclization of 5-carboxymethylproline to yield carbapenam-3-carboxylic acid
carbapenam-3-carboxylic acid: isolated from serratia & erwina sp.; ; rn given refers to (2r-cis)-isomer
carbapenem-3-carboxylic acid: from species of serratia & erwinia; carbapenam antibiotic
carbapenemase: from bacteroides fragilis; a zinc-containing beta-lactamase; hydrolyzes carbapenems & cephamycins; resistant to clavulanic acid, but sensitive to zn+ binding reagents; genbank m63556 and m34831
carbaryl hydrolase, Arthrobacter: catalyzes the conversion of carbaryl to 1-naphthol, carbon dioxide, and methylamine
carbaspirin calcium, thiamine nitrate drug combination: contains calurin (calcium acetylsalicylic carbamidate); vitamin b1, & aluminum hydroxide
carbazole 1,9a-dioxygenase: catalyzes oxygenation of angular position next to nitrogen of carbazole ring system
carbazole-1-acetic acid: used for the bioanalysis of diclofenac
carbendazim: carcinogen when combined with sodium nitrite; principle metabolite of thiophanate methyl & benomyl
carbobenzoxy-Glu-Lys-CO-Arg-CO-NH(CH2)2Ph: inhibits both arg-gingipain and lys-gingipain
carbobenzoxy-alanyl-alanyl-borophenylalanyl: a tripeptide boronic acid-containing inhibitor of chymotrypsin
carbobenzoxy-glycyl(p)-leucyl-alanine: gly(p) is used to indicate that the trigonal carbon of the normal peptide substrate has been replaced by the tetrahedral phosphorus of a phosphonamidate group in the thermolysin inhibitors
carbobenzoxy-phenylalanyl(p)-leucyl-alanine: phe(p) is used to indicate that the trigonal carbon of the normal peptide substrate has been replaced by the tetrahedral phosphorus of a phosphonamidate group in the thermolysin inhibitors
carbobenzoxyargininamide-7-yl-4-methylcoumarin: used for measuring trypsin-like activity
carbobenzoxyglycyl-prolyl-arginine-4-nitroanilide: chromogenic aminopeptidase substrate
carbobenzoxyglycyl-prolyl-leucyl-glycyl-proline: substrate for detection of clostridium collagenase & neutral proteinase
carbobenzoxyglycylphenylalanine: used as substrate for carboxypeptidase b; rn given refers to (l-phe)-isomer
carbobenzoxyglycylphenylalanine amide: used as substrate for metalloendopeptidases; rn given refers to (l)-isomer
carbobenzoxyleucyl-leucyl-glutamyl-2-naphthylamide: chromogenic substrate
carbobenzoxyphenylalanyl-phenylalanyl-glycine: rn given refers to (d)-phe-(l)phegly cpd; blocking group is on the amino-terminus
carbobenzoxyphenylalanylglycine: rn given refers to (l)-isomer
carbocyanine dye DiIC12(3): used for long-term labeling of rat motoneurons in mixed-population spinal cord cultures
carbocyclic 5-iodo-2'-deoxyuridine: rn given refers to (+-)-isomer
carbodiimide binding proteins: a subunit of the f0 complex of the mitochondrial h+-translocating atpase; contains a high percentage of hydrophobic amino acids and is devoid of histidine, tryptophan, cysteine, and lysine; studied in thermophilic bacterium ps3, rat, and e coli
carboetomidate: a pyrrole analog of etomidate designed not to suppress adrenocortical function
carbohydrase: contains sialidase, fucosidase, hexosaminidase & beta-galactosidase
carbohydrate-binding protein 70, human: a glycoslylated lectin that interacts through either glycan-lectin or protein-protein interactions; a nuclear glycoprotein; expressed in tumoral & healthy cells of the macrophage lineage; has been sequenced
carbohydrate-binding protein, nematophagous fungi: found on traps of nematophagous fungi; binds to n-acetyl-d-galactosamine on the nematode surface; results in consumption of nematode by fungus; mw 20,000
carbol-fuchsin solution: saturated alcoholic solution of basic fuchsin containing also aqueous phenol, boric acid, acetone & resorcinol
carboline-benzoquinolizidine alkolid deoxytubulosine: an emetine analog from indian medicinal plant; alangium lamarckii
carbomycin 3-O-acetyltransferase: involved in carbomycin biosynthesis in streptomyces thermotolerans; referred to as macrolide 3-o-acyltransferase in text; amino acid sequence given in first source; genbank d30759
carbon dioxide receptor: found in the nasal or vomeronasal membranes of tegu lizard; affects ventilatory sensitivity
carbon dioxide reduction factor: coenzyme of methanogenesis from carbon dioxide; can exist in amine & formamide form