NLK-NML/MeSH-CZ-2025-notes huggingface dataset:
ndvA protein, Rhizobium meliloti: from rhizobium meliloti; required for beta (1--2)glucan export and for nodulation of legume roots & has homology to the atp-binding export protein hlyb; amino acid sequence given in first source
ndx1 protein, plant: a class of plant homeobox genes is expressed in specific regions of determinate symbiotic root nodules; amino acid
neamphamide A: hiv-inhibitory depsipeptide from the papua new guinea marine sponge neamphius huxleyi
neanoside B: has hepatoprotective activity; isolated from neanotis wightiana
neaumycin B: isolated from the soil actinomycete streptomyces sp. neau-x211
neaumycin C: isolated from the soil actinomycete streptomyces sp. neau-x211
neb protein, Drosophila: involved in failure of cytokinesis; amino acid sequence given in first source ; refseq nm_057469
nebacumab: a human monoclonal igm antibody that binds specifically to the lipid a domain of endotoxin
nebracetam: rn given refers to parent cpd; agonist for muscarinic receptors
nebulin: giant myofibrillar protein; mol mass 800 kda; present in vertebrate & invertebrate striated muscle
nebuloside B: enhances toxicity of saporin; isolated from gypsophila arrostii
nec protein, Drosophila: isolated from drosophila; amino acid ; genbank aj245444
necatorin: from edible mushroom lactarius necator; consists of above 2 isomeric forms
necdin: brain-specific mrna encoding nuclear protein expressed in neurally differentiated embryonal carcinoma cells p19
necic acid: occur as diesters of pyrrolizidine bases in alkaloids; rn given refers to (z)-isomer
necitumumab: a fully human antibody that has similar antitumor potency as the chimeric cetuximab/erbitux and might represent a safer therapeutic alternative in egf receptor inhibition
necrostatin-1i: a supposedly inactive analog of necrostatin-1 that may actually have some cardioprotective activity
necrox-7: protective agent and necrosis modulator; composed of c25h32n4o4s2 with mw 516.67
nectamazin A: platelet inhibitor from leaves of nectandra amazonum nees. (lauraceae)
nectamazin B: platelet inhibitor from leaves of nectandra amazonum nees. (lauraceae)
nectamazin C: platelet inhibitor from leaves of nectandra amazonum nees. (lauraceae)
nectandrin-B: antifungal lignan from the seeds of myristica fragrans
nectarin 4 protein, Nicotiana tabacum: functions as pathogen surveillance molecule
nectarin V protein, Nicotiana tabacum: catalyzes the conversion of glucose and molecular oxygen to gluconic acid and h(2)o(2)
nectin-like molecule 1, rat: high abundance protein in cerebellar neurons genbank q99n28
nectriapyrone C: from a marine-derived fungus nectria sp. hls206 associated with the marine sponge gelliodes carnosa
nectriapyrone D: from a marine-derived fungus nectria sp. hls206 associated with the marine sponge gelliodes carnosa
nedasin: binds pdz domains of ne-dlg/sap102; amino acid ; genbank af019638
neemfruitin A: antiplasmodial from the fruits of neem, azadirachta indica, a traditional antimalarial plant used by asian and african populations
neemfruitin B: antiplasmodial from the fruits of neem, azadirachta indica, a traditional antimalarial plant used by asian and african populations
nefiracetam: antagonizes amnestic effects of picrotoxin or bicuculline
negative elongation factor: a multisubunit complex; cooperates with drb sensitivity-inducing factor (dsif) to repress rna polymerase ii transcription elongation, do not confuse with nelf protein - nasal embryonic lhrh factor
negundoside: an antioxidant irridiod glycoside from leaves of vitex negundo
nej protein, Drosophila: has been sequenced; refseq nm_079903
neladenoson bialanate: a prodrug of neladenoson, a partial adenosine a1 receptor agonist
nelex: solution containing condensation product of formalin & cresolsulfonic acid, 36%; dioxydimethyldiphenylmethanedisulfonic acid polymerate 36% in h2o, ph 0.6; pessaries 0.09g
nelotanserin: a 5-ht2a inverse agonist for treating insomnia
nemadectin: ; isolated from streptomyces cyaneogriseus sp. noncyanogenus; used against psoroptes ovis as an insecticide
nemitin protein, mouse: a map8/map1s interacting protein with wd40 repeats
nemo like kinase, Xenopus: phosphorylates tcfs bound to beta-catenin; amino acid sequence in first ; refseq nm_001091101
nemo-like kinase, zebrafish: a co-activator of wnt signaling; genbank ay562552
nemolizumab: humanized antihuman interleukin-31 receptor a antibody
nemy protein, Drosophila: a cytochrome b561 involved in learning and memory; has been sequenced
neo-angin: combination of 2,4-dichlorobenzyl alcohol, 4-pentyl-3-cresol, anise oil, camphor oil, mentholatum, menthae piperitae oil; used for throat infections
neo-cholex powder: combination drug used as gallbladder contracting agent; contains vegetable oil, sugar, milk fat, lecithin, casein, cocoa
neoagarobiose: rn given refers to neoagarobiose, (d-gal-l-galp)-isomer
neoagarobiose hydrolase: splits the disaccharide neoagarobiose to monosaccharides
neoamphimedine: a pyrido[4,3,2-mn]acridine from indo-pacific sponge genus xestospongia
neobiphylline: combination of theophylline, dyphylline & proxyphylline used in asthma therapy
neobudofficide: a flavonoid compound isolated from buddleia officinalis used to cure eye inflammation in china
neocaesalpin C: a cassane diterpenoid from the seeds of caesalpinia bonduc (fabaceae)
neocaesalpin D: a cassane diterpenoid from the seeds of caesalpinia bonduc (fabaceae)
neocarratetraose 4-O-monosulfate beta-hydrolase: hydrolyzes the beta-glycoside linkage to give neocarrabiose & neocarrabiose 4-o-sulfate
neocarzilin A: an antineoplastic agent produced by streptomyces carzinostaticus
neocarzilin B: an antineoplastic agent produced by streptomyces carzinostaticus
neocarzilin C: an antineoplastic agent produced by streptomyces carzinostaticus
neocassumunarin A: promotes neurite outgrowth and inhibits amyloid beta aggregation; isolated from zingiber purpureum
neochamaejasmin A: cytotoxic compound from the roots of a traditional chinese medicine, stellera chamaejasme l.; inhibits human prostate lncap cancer cells
neochymotrypsinogen: a slowly activating form of chymotrypsinogen, forms chymotrypsin after tryptic cleavage; formed by a limited proteolysis of bovine chymotrypsinogen a by added alpha-chymotrypsin; further proteolysis at asn 148-ala 149 gives ala-form & at tyr 146-thr 147 gives thr-form
neocidol powder: vet dusting powder containing dimpylat(diazinon) & dichloroxylenol; in chemline neocidol is synonym for diazinon
neocimicigenoside A: cycloartane glycoside from the rhizomes of cimicifuga racemosa
neocimicigenoside B: cycloartane glycoside from the rhizomes of cimicifuga racemosa
neocleistantoxin: cytotoxic lignan from fruits of cleistanthus indochinensis
neocomplanine A: from the extract of marine fireworm, eurythoe complanata
neocomplanine B: from the extract of marine fireworm, eurythoe complanata
neocopiamycin B: from streptomyces hygroscopicus var. crystallogenes
neocosmosin A: neocosmospora sp.-derived resorcylic acid lactone with in vitro binding affinity for human opioid and cannabinoid receptors
neocosmosin B: neocosmospora sp.-derived resorcylic acid lactone with in vitro binding affinity for human opioid and cannabinoid receptors
neocosmosin C: neocosmospora sp.-derived resorcylic acid lactone with in vitro binding affinity for human opioid and cannabinoid receptors
neocryptolepine: isolated from the roots of the african plant cryptolepis sanguinolenta
neoculin protein, Curculigo latifolia: sweetening agent; a heterodimeric protein from the fruit of curculigo latifolia that has both sweetness and a taste-modifying activity that converts sourness to sweetness; databank pdb/2d04
neocuproine: spectrophotometric determination of copper and ultramicro blood sugar determinations; structure; rn given refers to parent cpd
neodactyloquinone: from the okinawan marine sponge dactylospongia elegans
neodecanoic acid: mixture of di-substituted saturated decanoic acids used as dessicant for onion foliage prior to harvest
neodictyoprolenol: a putative dictyopterene intermediate; isolated from the japanese brown alga, dictyopteris
neoechinulin A: from the marine-derived fungus aspergillus sp.
neoeriocitrin: protects against autophagy-inhibiting effects of okadaic acid; isolated from drynariae rhizome
neogenin: a member of the immunoglobulin superfamily and related to dcc protein; amino acid ; genbank u07644
neohalicholactone: isolated from the marine sponge halichondria okadai
neohalichondramide: oxazole-containing metabolite from the sponge chondrosia corticata
neohecogenin-3-O-glucopyranosyl-1-2-glucopyranosyl-1-4-galactopyranoside: isolated from tribulus terrestris
neohecogenin-3-O-glucopyranosyl-1-4-galactopyranoside: isolated from tribulus terrestris
neohyacinthoside: isolated from bulb or northoliron hyacinthum (wils.) staff
neoirietetraol: cytotoxic to brine shrimp; from the okinawan red alga laurencia yonaguniensis (rhodomelaceae)
neoisoliquiritin: inhibits angiogenesis; isolated from licorice root; isoliquiritin is the (e)-isomer; ; isoliquiritin is also available
neoisostegane: rn given from ca index guide; rn not in chemline 12/84
neojiangyouaconitine: from aqueous extract of aconitum carmichaeli debx; mf c33-h47-n-o9
neolactotetraosylceramide alpha-2,3-sialyltransferase: catalyzes formation of lm1 and cmp from cmp-n-acetylneuraminate and neolactotetraosylceramide
neolitacumone A: isolated from the stem bark of neolitsea acuminatissima (lauraceae)
neolitacumone B: isolated from the stem bark of neolitsea acuminatissima (lauraceae)
neolitacumone C: isolated from the stem bark of neolitsea acuminatissima (lauraceae)
neolitacumonine: from the stem bark of neolitsea acuminatissima (lauraceae)
neomaclafungin A: from a marine-derived of actinoalloteichus sp.
neomangicol C: from a marine fungus of the genus fusarium with varied bioactivity
neomedrol-veriderm: combination of methylprednisolone, neomycin, methylparaben & butyl-p-hydroxybenzoate
neomycin sulfate, pyridine carboxylate of dexamethasone, tyzanol drug combination: combination drug; contains tyzanol, the pyridine carboxylate of dexamethasone & neomycin sulfate
neomycin, prednisolone, surfen, trypsin-chymotrypsin drug combination: combination drug which contains prednisolone, surfen, neomycin, trypsin-chymotrypsin
neomyosuppressin: myoinhibiting neuropeptide from the grey fleshfly, neobellieria bullata & drosophila
neonectrolide A: an oxaphenalenone spiroketal from the fungus neonectria sp.
neopaleaceolactoside: antifungal from the rhizome of polygonum paleaceum
neoparyl-framycetin: combination of framycetin sulfate & double heparinate of neosynephrine & methylglucamine
neopeltolide: a macrolide from a lithistid sponge of the family neopeltidae
neopentaene: polyenic macrolide antibiotic from streptomyces sp. h.a.c.c. 2336
neopetrocyclamine A: alkaloid from the sponge neopetrosia cf exigua
neopetrocyclamine B: alkaloid from the sponge neopetrosia cf exigua
neopetrosiamine A: cytotoxic bis-piperidine alkaloid from the caribbean sea sponge neopetrosia proxima
neopetrosiquinone A: from the deep-water sponge neopetrosia cf. proxima
neopetrosiquinone B: from the deep-water sponge neopetrosia cf. proxima
neopikromycin: from the pikromycin biosynthetic pathway of streptomyces venezuelae
neoplasm-associated factor: protein mw 60,000; consistently present in plasma of cancer patients, but absent in healthy individuals; present in amniotic fluid
neopredin: a gel containing prednisolone, neomycin sulfate & chlorhexidine for treatment of hemorrhagic periodontitis
neopullulanase: from bacillus stearothermophilus; hydrolyzes alpha-(1--4)glucosidic linkages & specific alpha-(1--6)glucosidic linkages of several branched oligosaccharides to produces panose, maltose & glucose
neopyrrolomycin B: antibiotic from streptomyces sp. with potent activity against gram-positive pathogens
neopyrrolomycin C: antibiotic from streptomyces sp. with potent activity against gram-positive pathogens
neopyrrolomycin D: antibiotic from streptomyces sp. with potent activity against gram-positive pathogens
neoquassin: a cyp1a1 inhibitor isolated from picrasma excelsa
neorauflavane: an inhibitor of tyrosinase monophenolase; isolated from campylotropis hirtella
neorautenol: isolated from erythrina addisoniae, induces apoptotic cell death accompanied by inhibition of erk phosphorylation
neorogioltriol: has both analgesic and anti-inflammatory activities; isolated from the red algae laurencia glandulifera
neosansalvamide: a cytotoxic cyclic pentadepsipeptide, produced by fusarium solani kccm90040 isolated from fusarium-contaminated potato in korea
neosartoryadin A: fumiquinazoline alkaloid from a mangrove-derived fungus, neosartorya udagawae hdn13-313
neosartoryadin B: fumiquinazoline alkaloid from a mangrove-derived fungus, neosartorya udagawae hdn13-313
neosergeolide: isolated from the amazonian medicinal plant picrolemma sprucei (simaroubaceae)
neosiphoniamolide A: a cyclodepsipeptide; from the marine sponge neosiphonia superstes
neosolaniol: rn given refers to (3 alpha,4 beta,8 alpha)-isomer
neosugar: mixture of 1f-(1-beta-fructofuranosyl), kestose & nystose
neosulfakinin I: amino acid sequence given in first source; isolated from the fleshfly, neobellieria bullata; a myotropic peptide with a putative sulfated tyrosine residue; may be c-terminally amidated
neosulfakinin II: isolated from the fleshfly, neobellieria bullata; a myotropic peptide with a putative sulfated tyrosine residue; may be c-terminally amidated; has been sequenced
neosymbioimine: from the symbiotic marine dinoflagellate symbiodinium sp
neotanshinlactone: has antineoplastic activity; isolated from salvia miltiorrhiza
neothyonidioside: fungicidal from the sea cucumber, australostichopus mollis
neothyoside B: a triterpenoid glycoside; isolated from the pacific sea cucumber neothyone gibbosa
neotizol: consists of neomycin sulfate, ethyl cellulose, castor oil, absolute alcohol, freons
neovestitol: isoflavonoid isolated from brazilian red propolis; has anti-inflammatory properties
neovibsanin A: isolated from viburnum awabuki; has neurotrophic activity in pc12 cells
neovibsanin F: rearranged vibsane-type diterpene from viburnum suspensum
neoxanthin: one of the main carotenoids in chloroplasts of higher plants and algae; rn given refers to (9'-cis)-isomer
neoxanthin synthase: catalyzes the conversion of violaxanthin to neoxanthin; amino acid ; genbank y18297
nepenthin protein, rat: approximately 16kda protein isolated from rat small intestine & bile duct which inhibits binding of diazepam to specific benzodiazepine binding sites
nepetaefolin: spiro dihydrofuran diterpene component of leonotis nepetaefolia extract which showed antineoplastic action
nepetalactol: a sex pheromone isolated from the potato aphid, macrosiphum euphorbiae
nepetalactone: rn given for (4as-(4aalpha,7alpha,7aalpha))-isomer
nepheline syenite: nepheline is a rock composed of various silicates; syenite is a rock composed of ka(1) silicate; constituent of an aluminum porcelain ceramic which contains 95% aluminum oxide & 5% nepheline syenite; used for dental implants
nepheliosyne A: isolated from the okinawan marine sponge xestospongia
nephrin: gene nephrin is mutated in congenital nephrotic syndrome; amino acid ; genbank f19541; refseq nm_019459 (mouse), nm_004646 (human), nm_022628 (rat)
nephritis antigen, GP 90, mouse: from glomerular capillary wall of rat & mouse
nephritis plasmin binding protein, Streptococcus: a 46-kd extracellular protein from nephritogenic streptococci; previously described as zymogen (streptococcal proteinase precursor); related to nsap-strep; has been sequenced; has cysteine-type peptidase activity
nephritis-strain associated protein, group A Streptococcus: extracellular streptokinase associated with nephritogenic streptococci; mw 46,000; isolated from patient with acute post-streptococcal glomerulonephritis
nephritogenoside: isolated from a variety of tissue types; receptor glycoprotein for concanavalin a from rat glomerular basement membrane
nephrocalcin: a strongly acidic glycoprotein present in normal urine, which inhibits calcium oxalate crystal growth and has been isolated from urinary stone matrix
nephrocan protein, mouse: a kidney-specific leucine-rich repeat protein; genbank ay938536
nephrocystin 1, C elegans: plays important and redundant roles in facilitating ciliary sensory signal transduction; has been sequenced
nephrocystin 4, C elegans: plays important and redundant role in facilitating ciliary sensory signal transduction; refseq: mrna sequence nm_073581; product np_505982
nephronectin: associates with integrin alpha8beta1 in embryonic kidney; amino acid
nephrophyt: derived from bearberry (orthosiphon stamineus) leaf extract; has antioxidant activity
nephrosin: zinc endopeptidase and member of astacin family; isolated from the carp cyprinus carpio; amino acid ; genbank u62621
nephthenol 15-O-beta-D-quinovoside: from asterothamnus centrali-asiaticus from gobi desert
nepmucin, mouse: mediates l-selectin-dependent lymphocyte rolling and promotes lymphocyte adhesion under flow; has four isoforms a,b,c,d; genbank ab243063-6
neprilysin 2, rat: a metalloprotease that belongs to the m-13 sub-family of zinc-dependent metallopeptidases; almost exclusively expressed in selected neuronal populations of the brain and spinal cord; the only exceptions were the intermediate and anterior lobes of the pituitary as well as the choroid plexuses, where nep2 was also strongly expressed; these localisations as well as those in the hypothalamic nuclei, together with the previously established pattern of cleaved peptides, suggest the involvement of nep2 in the metabolism of neurohormones of the hypothalamo-pituitary axis; has been sequenced
nequinate: minor descriptor (75-88); on line & & index medicus search quinolines (75-88)
neratinib: an orally active, irreversible inhibitor of the her-2 tyrosine kinase
nereistoxin: toxin isolated from marine segmented worm, lumbriconereis heterodopa; rn given refers to parent cpd
nerfilin I: a microbial metabolite inducing neurite outgrowth of pc12 cells; isolated from streptomyces halstedii 2723-sv2
nerfin-1 protein, Drosophila: zn-finger transcription factor gene expressed in the developing nervous system; amino acid
nerfin-2 protein, Drosophila: zn-finger transcription factor gene expressed in the developing nervous system; amino acid
neriifolin: ; rn given refers to alpha-l-glucopyranosyl(3beta,5beta)-isomer
nerispirdine: inhibits batrachotoxin binding to voltage-dependent sodium channels; hp-184 is the hcl salt
nerol oxide-8-carboxylic acid: from the peels of clausena lansium
nerolidol: sesquiterpene; rn given refers to cpd without isomeric designation; nerol is also available
nerolidol-3-O-alpha-L-rhamnopyranosyl-(1-6)-beta-D-glucopyranoside: from the leaves of eriobotrya japonica
nerolidol-3-O-rhamnopyranosyl-1-4-rhamnopyranosyl-1-2-(rhamnopyranosyl-1-6)-glucopyranoside: isoalted from eriobotrya japonica leaves
nerosin: antierosion agent in soil from shale oil containing benzopyrenes; russian drug
nerve growth factor (10-25,75-88): trypsin fragment; unsymmetrical double chain cystine peptide; amino acid sequence given in first source
nerve growth factor (75-88): rn given for all (l)-isomer; amino acid sequence given in first source
nerve growth factor, gamma: a 26 kda glycoprotein, member of the kallikrein family of serine proteinases; inhibited by human & murine alpha2-macroglobulin; amino acid sequence has been determined
nervonin A: cytotoxic pentacyclic ent-kauranoid from isodon nervosus
nervosine VII: a saturated pyrrolizidine alkaloid isolated from the plant of liparis nervosa
nervous system involved sulfotransferase: a sulfotransferase expressed by a subset of neurons and post synaptic targets, shows extensive homology to a chondritin-6-sulfotransferase and limited homology to other sulfotransferases; genbank af079875
neryl 2-methylbutanoate: male-produced aggregation pheromone from western flower thrips frankliniella occidentalis
neryl formate: airborne aggregation pheromone for the american house dust mite (dermatophagoides farinae) and the european house dust mite (d. pteronyssinus); has potential to be used as part of a lure-and-kill system for dust mite control
nes protein, Drosophila: isolated from drosophila; controlled by hox proteins during embryogenesis; amino acid
nes protein, Staphylococcus aureus: nes - nicking enzyme of staphylococci; a single-stranded endonuclease on the staphylococcal plasmid pgo1; genbank u50629
nesfatin-1-like peptide, rat: a fragment of nucleobindin 1
nesprin 4 protein, mouse: an outer nuclear membrane protein involved in cell polarization; refseq np_705805
nesprin-3 protein, mouse: an outer nuclear membrane protein that associates with plectin; amino acid
net protein, Drosophila: a bhlh protein that represses rhomboid; genbank af303350; do not confuse with ets-related protein, also known as net protein
netagen: contains 4 mg 17 beta-estradiol & 3 mg norethindrone acetate
netamine K: an antimalarial alkaloid from the marine sponge biemna laboutei
netarsudil: a rho kinase inhibitor with norepinephrine transport inhibitory activity that reduces production of aqueous humor
nethaprin dospan: bronchodilator agent combination of etaphedrine, ambuphylline, doxylamine succinate & phenylephrine.hcl in a carboxypolymethylene vehicle which releases active ingredients slowly
netrin-2: an axon outgrowth-promoting factor from chick brain; amino acid ; genbank l34550
netrin-3: a homolog of ntn2l expressed in sensory ganglia with differential binding to netrin receptors; amino acid
netrin-G1: glycosyl phosphatidylinositol-linked mammalian netrin that is functionally divergent from classical netrins; amino acid
netzahualcoyone: from plant family celastraceae; broad-spectrum activity against gram-positive bacteria and yeasts; rn given refers to (20alpha,21beta)-isomer; rn for cpd without isomeric designation not avail 5/91
neudesin protein, mouse: has neurotrophic activity; expressed primarily in nervous tissue in embryos but more widely expressed postnatally; amino acid
neuferricin protein, mouse: an extracellular heme-binding protein; refseq nm_001024926
neugrin: involved in neuronal differentiation; amino acid ; genbank ab029315 (human) and ab047544 (mouse)
neur protein, Drosophila: a e3 ubiquitin ligase; expressed in precursors of larval and adult neurons; amino acid sequence given in first source; refseq nm_001170092
neurabin: neurabin - neural tissue-specific f-actin-binding protein; mw 180 kda;
neural CEPU-1 protein, chicken: a 51-kda gpi-linked cell surface glycoprotein, member of immunoglobulin superfamily, expressed in developing cerebellar purkinje cells; cepu-se is an isoform; amino acid sequence given in first source
neural cell surface antigen BSP-2: expressed in neural tissue of higher animals; mediates cell-cell adhesion during neuronal development; identical to bacterial poly-alpha-2,8-neuac; see also capsular polysaccharide k1 and meningococcal group b polysaccharide
neuraminin: high mw, neutral substance from strepomyces sp.; composed mainly of equal parts of glucose & mannose; inhibits viral but not bacterial neuraminidase
neuraxin: amino acid sequence given in first source; related to microtubule-associated protein 5; may be implicated in neuronal membrane-microtubule interactions; do not confuse with neuraxin (methocarbamol)
neuregulin beta: an alternatively spliced isoform of neuregulin-1 from spinal cord
neuregulin-4: refseq nm_138573 (human); nm_032002.2 (mouse); nm_001191109.1 (rat)
neurelax: a herbal medicine; used in treatment of psychological stress; no other info avail 1/90
neurestin: a putative transmembrane molecule implicated in neuronal development; has been sequenced
neurexin II: encodes 2 isoforms - alpha and beta with large and small extracellular domains respectively; refseq nm_001205234 (neurexin2, mouse)
neurexin IIIalpha: member of the neurexin gene family; highly homologous to neurexin ialpha and iialpha; amino acid sequence given in first source
neurexin IIIbeta: amino acid sequence (bovine) given in first source; genbank l27869
neurexin Ibeta: amino acid sequence (rat & bovine) given in first source; genbank l27870
neurexophilin: a neuropeptide-like glycoprotein from mammalian brain; neurexophilin 1-4 represent products of similar genes; may function as ligand for alpha-neurexins; refseq nm_008751 (nxph1, mouse); nm_012994 (nxph1, rat); nm_152745 (nxph1, human); nm_007226 (nxph2, human); nm_007225 (nxph3, human); nm_008752 (nxph2, mouse); nm_007224 (nxph4, human); nm_130858 (nxph3, mouse)
neurin-1: an axonal growth-related cell surface molecule, involved in neuron-glia interaction; mw 68 kda
neurite-inducing factor: induces neurite formation in pc12 cells; from submaxillary gland; mw 20,000
neurocatin: a neuroregulator factor isolated from mammalian brains; it is a powerful affector of protein phosphorylation in rat striatal synaptosomes; it appears to be a small peptide with a mw range 2-2.5 kda
neurochondrin: has 16% leu residues; expression restricted to brain & bone; amino acid
neurochondrin-2: contains 712 amino acids with molecular weight of 77.2 kda; amino acid ; genbank ab018740
neurod4 protein, zebrafish: a neural basic helix-loop-helix protein that regulates early neurogenesis in the zebrafish; expressed in neurons of the central nervous system and in subsets of cranial ganglia; 347 amino acid residues; genbank af204240
neurod6 protein, Xenopus: a mammalian factor structurally related to the product of drosophila proneural gene atonal; specifically expressed in the nervous system
neuroendocrine regulatory peptide-1, human: modulates body fluid homeostasis; amino acid
neuroendocrine regulatory peptide-1, rat: modulates body fluid homeostasis; amino acid
neuroendocrine regulatory peptide-2, human: modulates body fluid homeostasis; amino acid
neuroendocrine regulatory peptide-2, mouse: stimulates glucose-induced insulin secretion
neuroendocrine regulatory peptide-2, rat: modulates body fluid homeostasis; amino acid
neurofilament protein H: amino acid and nucleotide sequence given in first source; mw 200 kda; refseq nm_021076 (human), nm_010904 (mouse), nm_012607 (rat)
neurofilament protein L: amino acid sequence given in first source; different from neurofilament proteins m & h; refseq nm_006158 (human), nm_010910 (mouse)
neurofilament protein M: mw 150 kda; a neurofilament triplet protein; refseq nm_005382 (human), nm_008691 (mouse)
neurofilament protein NF 60: from squid; amino acid sequence given in first source
neurofilament protein NF 68: has been sequenced; neuron-specific protein found in axons and dendrites
neurofilament protein NF 70: from squid; amino acid sequence given in first source
neurofilament-associated kinase: phosphorylates a subset of peptides in vitro which are phosphorylated in vivo in cultured neurons
neurog1 protein, zebrafish: involved in neurogenesis; genbank af036149
neurogenin-1, rat: mediates erythropoietin enhanced differentiation of adult neural progenitor cells; refseq mrna sequence nm_019207
neuroglia-associated protein 185 kDa: a 185 kda marker for astroglial cells in cns; partial amino acid sequence given in first source
neurohormone C: cardioactive, coronarydilatory substance from bovine hypothalamus; polycyclic cpd of non-peptide
neurokinin A (3-10), lysyl(3)-glycyl(8)-R-lactam-leucine(9)-: neurokinin receptor agonist
neurokinin A (4-10), Lys(5)-MeLeu(9)-Nle(10)-: a selective nk-2 receptor agonist
neurokinin A (4-10), Lys(5)-Tyr(I2)(7)-MeLeu(9)-Nle(10)-: a radioligand selective for the tachykinin nk2 receptor
neurokinin A (4-10), Trp(7)-beta-Ala(8)-: a selective nk-2 receptor antagonist
neurokinin A (4-10), beta-Ala(8)-: selective nk-2 tachykinin receptor
neurokinin A (4-10)-OH: the c-terminal free acid derivative of neurokinin a (4-10)
neurokinin A(4-10), Tyr(5)-Trp(6,8,9)-Lys(10)-: tachykinin receptor antagonist
neurokinin B, Pro(2)-Trp(6,8)-Nle(10)-: competitive antagonist of neurokinin b
neurokinin receptor 4: a tachykinin receptor, functionally antagonized by an endogenous opioid peptide; amino acid sequence given in first source
neuroligin 1: a neuronal cell surface protein; binds to beta-neurexins that lack an insert in the alternatively spliced sequence of the g domain; amino acid sequence given in first source; genbank u22952
neuroligin 3: a brain-specific protein; binds to beta-neurexin; amino acid sequence given in first source; genbank u41663
neuromedin C: decapeptide isolated from porcine spinal cord; corresponds to the c-terminal decapeptide of gastrin-releasing peptide; bombesin-like peptide; rn given refers to all (l)-isomer
neuromedin N: peptide from porcine spinal cord with amino acid sequence homologous to cooh-terminal sequence of neurotensin
neuromedin N precursor: nucleotide sequence given for 170 amino acid protein in first source
neuromedin N-125: contains 125 amino acids including residues 24-148 of preproneurotensin n; may contain non-amino acid substances
neuromedin S: a neuropeptide of 36 amino-acid residues in rat brain
neuromedin U: amino acid sequence given in first source; contains 2 deletions and 9 substitutions compared with the neuromedin u 25
neuromedin U 25: 25 amino acid peptide from pig spinal cord with uterine stimulating activity; amino acid sequence given in first source
neuromedin U 8: 8 amino acid oligopeptide from pig spinal cord with uterine stimulating activity
neuromedin U 9: produces a concentration-dependent contraction of smooth muscle from the rat uterus; amino acid sequence given in first source
neuromedin U receptor: may be coupled to a g-protein; refseq nm_023100 (gpr66), nm_022275 (nmu2r), nm_020167 (human)
neuromelanin: lipomelanoprotein pigment found in human locus caeruleus & substantia nigra; composed of eumelanin and pheomelanin
neuron-specific p150: expressed exclusively in brain & localize in nerve terminals; partial amino acid sequence given in first source
neuron-specific p65: expressed exclusively in brain & localize in nerve terminals; partial amino acid sequence given in first source
neuronal Cdk5 activator (p25-p35): regulates & activates cyclin-dependent kinase 5 (cdk5); p25 is the truncated form of p35; amino acid sequence given in first & second source; genbank x80343
neuronal cell death inducible putative kinase: induced during neuronal cell death; amino acid
neuronal interleukin-16: a dual function pdz domain protein; serves as a secreted signaling molecule as well as a scaffolding protein; amino acid
neuronal nuclear antigen NeuN, human: expressed in 56% of epithelial neuroendocrine carcinoma
neuronal pentraxin: nptx1 is a secreted protein with homology to acute phase proteins of the immune system and is involved in the general uptake of synaptic macromolecules; refseq nm_153735 (rat); nm_002522 (nptx1, human); nm_002523 (nptx2, human); nm_008730 (nptx1, mouse); nm_058178 (nptxr, human); nm_028763 (nptxr, mouse); nm_030841 (nptxr, rat); nm_008987 (ptx3, mouse)
neuronal pentraxin receptor: binds pentraxins 1 and 2, as well as taipoxin-associated calcium-binding protein 49; amino acid
neuronal protein E1: an ankyrin-related potentially protective protein of the human filarial nematode onchocerca volvulus; member of the death domain protein family; amino acid sequence given in first source
neuronectin: human extracellular matrix protein found throughout the white matter of rostral brain segments; secreted by basic & acidic fibroblast growth factors
neuronostatin, mouse: inhibits cardiac contractile function via a protein kinase a- and jnk-dependent mechanism in murine hearts
neuroparasin A precursor, desert locust: scg-npp1 - s. gregaria neuroparsin-1 precursor; isolated from schistocerca gregaria; genbank aj296015
neuroparsin A: isolated from locusta migratoria; multifunctional neurohormone; exhibits effects of juvenile hormone, stimulates fluid reabsorption of isolated recta & induces an increase in hemolymph & triose levels
neuroparsin B: isolated from locusta migratoria; multifunctional neurohormone; exhibits effects of juvenile hormone, stimulates fluid reabsorption of isolated recta & induces an increase in hemolymph & triose levels
neuroparsin B precursor, desert locust: scg-npp2 - s. gregaria neuroparsin-2 precursor; isolated from schistocerca gregaria; genbank aj296016
neuropeptide B: ligand for the orphan receptors gpr7 and gpr8
neuropeptide DF2: an fmrfamide-related neuropeptide from crayfish, procambarus clarkii
neuropeptide F: amino acid sequence given in first source; mw 4433 da; from tubellarian artioposthia triangulata
neuropeptide F receptor, Anopheles gambiae: short neuropeptide f receptor in the african malaria mosquito, anopheles gambiae
neuropeptide F, Drosophila: a brain-gut peptide; amino acid ; genbank af117896
neuropeptide FF precursor (85-99), rat: reverses antinociceptive activity of morphine; affects g-proteins linked to opioid receptors; amino acid
neuropeptide FF receptor: ot7t022 is a g protein-coupled receptor that binds neuropeptide ff and bibp3226, an anorexigenic y1 receptor ligand; refseq nm_022146 (gpr147, human); nm_053036 (gpr74, human); nm_022291 (ot7t022, rat); nm_023980 (npgpr, rat); nm_133192 (gpr74, mouse)
neuropeptide K: 36-amino-acid tachykinin that contains neurokinin a (substance k), a 10-amino-acid tachykinin, at its c-terminus
neuropeptide S, 5-Cys(tBu)-: a neuropeptide s receptor antagonist
neuropeptide S, human: has anxiolytic and hypervigilant activities; genbank bd168686
neuropeptide S, mouse: induces anxiolysis, wakefulness, and hyperlocomotion; has been sequenced
neuropeptide S, tert-butylGly(5)-: a neuropeptide s receptor antagonist
neuropeptide W, rat: the endogenous npw, produced in brain, may play a physiologically relevant role in the neuroendocrine response to stress; has been sequenced
neuropeptide Y (1-27): evokes differential feeding responses in the rat; rn from toxlit
neuropeptide Y (1-30): an n-terminal fragment of neuropeptide y
neuropeptide Y (16-36): inhibits mucociliary activity in rabbit maxillary sinus but does not affect blood flow
neuropeptide Y (17-36): inhibits rat cardiac adenylate cyclase by interacting with receptors coupled to a pertussis toxin-sensitive g protein
neuropeptide Y (2-36): antagonizes the inhibitory action of neuropeptide y in guinea pig trachea
neuropeptide Y (24-36) amide, N-acetyl-(Leu(28,31))-: a presynaptic (y2) receptor-specific neuropeptide y analog
neuropeptide Y (24-36), Ac-(Leu(28,31))-: putative y2 receptor agonist
neuropeptide Y (27-36), Tyr(27,36)-Thr(32)-: d-npy(27-36) acts as an antagonist at one or more subtypes of the npy receptors in rat brain
neuropeptide Y (3-36): an angiogenic factor from the sympathetic nerves and endothelium
neuropeptide Y (Ac-25-36), cyclic (Lys(28)-Glu(32))-: a modified cyclic dodecapeptide analog of neuropeptide y is the smallest full agonist at the human y2 receptor
neuropeptide Y C-terminal flanking peptide: 30-amino acid neuropeptide widely distributed in central & peripheral nervous system
neuropeptide Y(13-36)amide, N-acetyl-(Leu(17,28,31)Gln(19)Ala(20,23))-: binds to postjunctional or y1 receptors to raise blood pressure and to prejunctional or y2 receptors to inhibit neurotransmitter release
neuropeptide Y, Ahx (5-17)-: amino acid sequence given in first source
neuropeptide Y, Ahx(5-24), gamma-Glu(2)-epsilon-Lys(30)-: amino acid sequence given in first source; a synthetic cyclic neuropeptide y analog; a y2 receptor agonist
neuropeptide Y-Y1 receptor: amino acid sequence given in first source; genbank d63818
neuropeptide Y2 receptor: a type 2 neuropeptide y receptor; has 31% identity with npy1 receptor; amino acid sequence given in first source; genbank u32500
neuropeptide Y4 receptor: a neuropeptide y receptor subtype; amino acid ; genbank af030245; refseq nm_005972 (human), nm_008919 (mouse), nm_031581 (rat)
neuropeptide Y5 receptor: a receptor involved in neuropeptide-y-induced food intake; has 456 amino acid residues; amino acid ; genbank u56078
neuropeptide Y6 receptor: a neuropeptide y receptor subtype; amino acid ; genbank af030245
neuropeptide Ya receptor: a npy receptor subtype in mammals; amino acid ; genbank af037400
neuropoietin, mouse: member of il-6 cytokine family signaling through the ciliary neurotrophic factor receptor; encoded by gene np on chromosome 7; genbank ay363390
neurosecretory protein, Locusta migratoria: from brain & corpora cardiaca of fifth instar locusts
neurospanin: a member of the tetraspanin family; isolated from chick nervous system; amino acid
neurosporaside: a tetraglycosylated sphingolipid from neurospora crassa
neurosporene: triterpenoid carotenoid; rn given refers to cpd without isomeric designation
neurostatin: from rat and bovine brain extracts; inhibits proliferation of cultured astrocytes
neurostenin: actomyosin-like protein isolated from mammalian brain nerve ending preparations
neurotensin (8-13): binds in human brain to the same site as neurotensin but with higher affinity
neurotensin (8-13), Asp(12)-: a competitive inhibitor of neurotensin; inhibits neurotensin-induced histamine release by mast cells
neurotensin (8-13), Asp(13)-: a competitive inhibitor of neurotensin; inhibits neurotensin-induced histamine release by mast cells
neurotensin (8-13), Lys(8)-: a neurotensin agonist that stimulates cyclic-gmp synthesis
neurotensin 69L: analog of neurotensin, nt(8-13)
neurotensin NT79: analog of neurotensin nt(8-13) with selective behavioral effects
neurotensin, N-alpha-(fluoresceinylthiocarbamyl)glutamyl(1)-: a biologically active fluorescent probe for labeling neurotensin receptors
neurotensin, azidobenzoyl-Lys(6)-Trp(11)-: labeled with 125i
neurotensin-degrading enzyme: thiol-dependent metalloproteinase which cleaves the arg(8)-arg(9) bond of neurotensin; some enzymes of this type can also cleave at the pro(10)-tyr(11) bond
neurotensin-like immunoreactivity: located within amcrine cells of pigeon retina
neurotoxic esterase: site of biochemical lesion in delayed neuronal degeneration produced by certain organophosphorus esters; insensitive to organophosphorus cpds such as paraoxon, but sensitive to mipafox
neurotoxin 5-1: alpha neurotoxin isolated from taiwan cobra; amino acid
neurotoxin I, Stichodactyla helianthus: rn given in first source; from the sea anemone strichodactyla helianthus
neurotoxin IIalpha (Leirus): from leirus quinquestriatus; slows inactivation of sodium channel
neurotoxin M9, scorpion: isolated from scorpion buthus eupeus; contains 66 amino acid residues with four disulfide bonds; amino acid sequence given in first source
neurotoxin Os3 protein, Orthochirus scrobiculosus: isolated from the black scorpion orthochirus scrobiculosus; amino acid
neurotoxin-binding protein, Clostridium: mw about 48 kda; amino acid
neurotractin protein, chicken: neurite outgrowth-promoting ig-like protein that interacts with cepu-1 and lamp; amino acid ; genbank aj132998 (short form); aj132999 (long form)
neurotractin protein, mouse: neurotractin/kilon promotes neurite outgrowth and is expressed on reactive astrocytes after entorhinal cortex lesion; amino acid
neurotrimin: a differentially expressed neural cell adhesion molecule; contains 3 immunoglobulin-like domains; shows 77% overall similarity to opiate-binding cell adhesion molecule (obcam); amino acid sequence given in first source; genbank u16845
neurotrophin 4: amino acid sequence given in first source; isolated from human and rat; homologous to xenopus and viper nt-4; rn given refers to human nt-4
neurotrophin 5: amino acid sequence given in first source; member of the nerve growth factor family
neurotrophin 6: amino acid sequences of alpha, beta, and gamma forms given in first source; alpha, beta, and gamma forms are 95% identical to each other
neurotropin: polysaccharide extracted from the inflammatory skin of rabbits treated with vaccinia virus
neurotropin 3, mouse: brain-derived neurotropic factor which plays a crucial role in brain development; partial base
neurymenolide A: isolated from the red alga neurymenia fraxinifolia
neurymenolide B: isolated from the red alga neurymenia fraxinifolia
neutral aminopeptidase, Plasmodium berghei: chloroquine-induced redistribution of enzyme may be the cause of hemoglobin accumulation in endocytic vesicles of malaria parasites
neutral lipid, phosphatidylcholine, phosphatidylethanolamine drug combination: extracts cholesterol from cellular membranes ; inhibits hiv infection of human peripheral blood lymphocytes or an immortalized helper t-cell line; contains neutral glycerides, phosphatidylcholine & phosphatidylethanolamine in 7:2:1 ratio
neutral protamine lispro insulin: a new intermediate-acting insulin consisting of lispro-protamine crystals
neutral protease II, Aspergillus oryzae: from aspergillus oryzae; zinc-containing metalloproteinase; mw 19.8 kda; contains 177 amino acids; amino acid sequence given in first source
neutral protease, Bacillus stearothermophilus: aspartame is produced by reverse reaction of this thermostable neutral protease; amino acid sequence of nprs is identical to nprm
neutral proteinase Pf105, Plasmodium falciparum: has specificity for the synthetic peptide glca-val-leu-gly-lys (or arg)-aec; active form is 68kda, native form is 105kda; sensitive to thiol reagents; a good candidate in the strategy to design parasite development inhibitors
neutral proteinase snpA, Streptomyces: amino acid sequence given in first source; mw 15,740
neutral proteinase, cervical: from culture media from rabbit uterine cervical fibroblasts; activates procollagenase; secreted as a proenzyme; activated by trypsin, plasmin or 4-aminophenylmercuric acetate
neutrophil basic proteins: isolated from lysosomal secretion granules of human granulocytes; neutrophil-derived protein found only in cytosol of neutrophils & constitutes at least 6% of the total protein of the neutrophil with mw approx 34-36,000
neutrophil chemotactic factor, Dirofilaria immitis: aa sequence given in first source; isolated from the adult worm; genbank d11438
neutrophil cytosol factor 40K: forms an activation complex with p47(phox) and p67(phox) with which it translocates to the membrane to associate with flavocytochrome b; ncf4 & p(40)phox are identical; mouse & human proteins are 86% homologous; amino acid sequence given in first source; genbank u59488 (mouse); refseq nm_008677 (mouse)
neutrophil cytosol factor 67K: translocation of cytosolic component p67phox is essential step in the activation of nadph oxidase in response to phorbol esters; amino acid sequence has been determined; subunit of leukocyte nadph oxidase
neutrophil cytosolic factor 1: amino acid sequence given in first source; required for activation of nadph oxidase superoxide production; absent in most patients with autosomal recessive chronic granulomatous disease; subunit of nadph oxidase system; a nucleoside triphosphate-binding protein;
neutrophil gelatinase-associated lipocalin protein, dog: biomarker; elevated in non-azotemic dogs with urinary tract infection
neutrophil immunoglobulin-like receptor 1: an immunoglobulin-like receptor expressed by neutrophilic granulocytes, encoded by a leukocyte receptor gene complex; amino acid
neutrophil migration inhibitory factor: from t lymphocytes; inhibits migration of human neutrophils; characterized by electrophoresis & microassay
neutrophil peptide 5: was sy to defensins until 2001; this is human: do not confuse with peptide np-5 (rabbit)
neutrophil-activating protein A, Helicobacter pylori: homologous to bacterioferritins; genbank u16121
neutrophil-specific antigen NA1, human: alloimmune neutropenia is due to na1 specific antibodies to this antigen; granulocyte antigen localized in the fcriii receptor
neutrophil-specific antigen NA3, human: granulocyte-specific human neutrophil-specific antigen
neutrophil-specific antigen SH: an alloantigen on the human neutrophil fcgamma-receptor; from alloimmune neonatal neutropenia; has been sequenced
neuwiedase: a nonhemorrhagic fibrin(ogen)olytic metalloproteinase isolated from bothrops neuwiedi venom; amino acid ; genbank af226274
nevadensin: from lysionotus pauceflora maxim; rn & n1 from 9th ci
nevadensin-7-sambubioside: from lysionotus pauciflorus
newbouldiaquinone A: from eriosema kraussianum n. e. br. (fabaceae) rootstock
neyarthros: cell extract from young animals; also contains sodium lauryl sulfate; affects cartilage after intra-articular administration
neythymun: sulfated lysate of thymus; contains alpha1-thymosin, thymopoietin, serum-thymus factor, and other components
nezulcitinib: a lung-selective pan-janus-associated kinase (jak) inhibitor
nfaE protein, E coli: amino acid sequence given in first source; homologous with cs3 protein
nfm-1 protein, C elegans: refseq nm_065935.3
nfrA protein, Azorhizobium caulinodans: rna-binding protein that stimulates the elongation of poly(a) tails; may be involved in the regulation of nifa; homologous to hf-i protein of escherichia coli; do not confuse with nrfa, a cytochrome c nitrite reductase (ec 1.7.2.2); do not confuse with nfra protein of e. coli, a bacteriophage n4 adsorption protein; amino acid sequence given in first source; genbank x76450
nfrB protein, E coli: an 85 kda inner membrane protein required for bacteriophage n4 adsorption; amino acid sequence given given in first source; genbank l16945
ng1 protein, Drosophila: expressed during larval life; highly homologous to ng-2 protein; amino acid sequence given in first source; refseq nm_057307
ng2 protein, Drosophila: expressed during larval life; highly homologous to ng-1 protein; amino acid sequence given in first source; refseq nm_057593
nhaR protein, E coli: na+/h+ antiporter regulatory protein; belongs to a large family of regulatory proteins (lysr); regulates nhaa, the sodium proton antiporter gene in escherichia coli; has been sequenced
nhr-8 protein, C-elegans: involved in xenobiotic resistance; isolated from caenorhabditis elegans; has been sequenced
niacytin: form of bound niacyn linked to polysaccharide which in turn is linked to a peptide; found in wheat
niaoduqing keli: also known as uremic clearance granule; used to treat chronic renal failure; consists of rheum palmatum, astragalus membranaceus, glycyrrhiza uralensis, atractylodes macrocephala, polygonum multiflorum, chrysanthemun morifolium, salvia miltiorrhiza, codonopsis pilosula, bupleurum chinense, morus alba, sophora flavescens, paeonia lactiflora, plantago asiatica, pinellia ternata, poria cocos, and ligusticum chuanxiong
nibentan: mf: c22-h29-n3-o3 hcl; mf does not agree with chemical name in text
nicastrin protein: a transmembrane glycoprotein modulates presenilin-mediated notch/glp-1 signal transduction
nickel carbonyl: rn given refers to cpd with mf of ni-(co)4
nickel hemoglobin A: hemoglobin a in which nickel replaces iron moiety
nickel hydroxide: rn given refers to cpd with mf of ni-(oh)2
nickel nitrate: rn given refers to cpd with mf of ni-(hno3)2
nickel rutile yellow: mixed-phase dye based on titanium dioxide (rutile) in which titanium ions are partialy replaced by nickel & antimony ions
nickel subsulfide: rn given refers to cpd with mf of ni3-s2; see also nickel sulfide: 16812-54-7
nickel sulfate: rn given refers to cpd with mf of ni(2+)-h2so4
nickel sulfide: rn given refers to cpd with mf of ni-s; see also nickel subsulfide: 12035-72-2
nickel(II) (2,12-dimethyl-3,7,11,17-tetraazabicyclo(11.3.1)heptadeca-1(17),2,11,13,15-pentaene) perchlorate: rn given refers to diperchlorate
nickel(II) 20-methyl-phytochlorin methyl ester: a bacteriochlorophyll c model compound
nickel(II) protoporphyrin IX: rn given for di-h cpd
nickel-(II) N-(2-hydroxyacetophenone)glycinate: has antineoplastic activity
nickel-glycyl-glycyl-histidine Hin recombinase (139-190): 55-residue protein; the ggh segment is a tripeptide ligand for transition metals such as cu(ii) or ni(ii) & hin (139-90) is a helix-turn-helix domain for specific dna binding
nickel-palladium alloy: used for magnetic induction of hyperthermia as a brain implant for therapy of brain neoplasms
nickel-sequestering renal glycoprotein, rat: mw 15,000-16,000 glycoprotein from rat kidney
niclosamidate: has activity against against oncomelania hupensis, intermediate host of schistosoma japonicum
nicobrevin: contains quinine, menthyl valerate, camphor & oil of eucalyptus; anti-smoking capsule
nicoflavin: with reported vasodilatation activity in one russian article; no other info available 1/28/83
nicolaioidesin A: a prenylated dihydrochalcone from the roots of renealmia nicolaioides
nicolaioidesin B: a prenylated dihydrochalcone from the roots of renealmia nicolaioides
nicolaioidesin C: a prenylated dihydrochalcone from the roots of renealmia nicolaioides
nicophyllin: combination of nicotinic acid & euphyllin (aminophyllin)
nicosulfuron: inhibits acetolactate synthase; accent is dupont brand name