NLK-NML/MeSH-CZ-2025-notes huggingface dataset:
1-(1-oxo-1-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)propan-2-yl)pyrrolidine-2,5-dione: has anticonvulsant activity
1-(1-phenylethyl)-1H-imidazole-5-carboxylic acid 2-fluoroethylester: possible pet imaging agent
1-(1-propylsulfonic)-3-methylimidazolium chloride: used as a bronsted acidic ionic liquid to support hydrolysis of lignocellulosic biomass to reducing sugars by zymomonas mobilis ax101
1-(10-((E)-3-phenyl-allyl)-3,10-diaza-bicyclo(4.3.1)dec-3-yl)propan-1-one: attenuates nociceptive transmission in animal models of experimental pain
1-(10-pyrenedecanoyl)-2,3-dioleoylglycerol: employed in the fluorometric assay of acid lipase or diagnosing wolman's & cholesteryl ester storage diseases
1-(12-amino-4,9-diazadodecyl)-2-methyl-3-hydroxy-4(1H)-pyridinone: a bidentate iron chelator
1-(13-(3',4'-methylenedioxyphenyl)-2E,4E,12E-tridecatrienoyl)-N-isopentylamide: insecticidal amide from fruits of piper nigrum linn
1-(14'-methylhexadecanoyl)pyrrolidine: isolated from member of the convolvulaceae family of tropical plants
1-(17,18-dithiatetratriacontandioyl)-bis(2-hexadecanoylglycero-3-phosphocholine): mechanistic probe of phosphatidyl exchange protein
1-(18F)fluoro-3,6-dioxatetracosane: for pet imaging of brain cancer with positron emitter-labeled liposomes
1-(1H-1,2,4-triazole)-2-(2,4-difluorophenyl)-3-(N-methyl-N-(4-iodobenzyl)amino)-2-propanol: has antifungal activity
1-(1H-1,2,4-triazole)-2-(2,4-diflurophenyl)-3-(N-methyl-N-(4-iodo-benzyl)amino)-2-propanol: antifungal
1-(1H-benzo(d)imidazol-2-yl)naphthalen-2-ol: a fluorescent probe for imaging aluminum(iii) ion
1-(1H-benzo(d)imidazol-5-yl)-5-(4-propoxyphenyl)imidazolidin-2-one: a glutaminyl cyclase inhibitor
1-(1H-imidazol-1-yl)-2-(2-phenyl-1H-phenanthro(9,10-d)imidazol-1-yl)ethanone: fluorescent reagent
1-(1H-indol-3-yl)-2,3-dihydroxy-5-methyl-hexane: from the south china sea sponge axinella sp.
1-(1H-indol-4-yloxy)-3-((2-(2-methoxyphenoxy)ethyl)amino)propan-2-ol: has antiarrhythmic activity
1-(2',3',4',6'-tetraacetylglucopyranosyloxyl)-1,4a,5,7a-tetrahydro-7-(acetomethyl)-cyclopentapyran-4-caroboxylic acid methyl ester: a penta-acetyl geniposide
1-(2',3'-dihdyroxypropyl)-2-en-3-methyl-6-hydroxy-yn-undecanoate: isolated from centella asiatica
1-(2',3'-epithio-2',3'-dideoxy-beta-D-lyxofuranosyl)thymine 5'-triphosphate: ; substrate for hiv and amv reverse transcriptases as well as dna polymerases
1-(2',3'-epithio-2',3'-dideoxy-beta-D-ribofuranosyl)thymine 5'-triphosphate: ; substrate for hiv and amv reverse transcriptases as well as dna polymerases
1-(2',4',5-trimethoxybenzyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline: 2',4',5'-trimethoxy analog of trimethoquinol
1-(2',4'-dihydroxy-3',5'-di-(3''-methylbut-2''-enyl)-6'-methoxy) phenylethanone: from acronychia pedunculata
1-(2',4'-dihydroxy-3'-methoxyphenyl)-7-(4'-methoxyphenyl)-3-heptanone: from the fruits of alpinia oxyphylla
1-(2',4'-dihydroxy-5'-methyl-3'-methylsulfanylmethyl-phenyl)-ethanone: from the fungus penicilliumcrustosum yn-ht-15
1-(2',4'-dinitroaminophenyl)-4,4,6-trimethyl-1,4-dihydropyrimidine-2-thiol: a chelating agent
1-(2',5'-bis-O-(tert-butyldimethylsilylribofuranosyl)-3-N-methylthymine)-3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide): ; specific against hiv-1 replication
1-(2',6'-difluorophenyl)-1H,3H-thiazolo(3,4-a)benzimidazole: anti-hiv agent; a non-nucleoside reverse transcriptase inhibitor
1-(2'-amino-3',3'-dimethylbutanoyl)pyrrolidine-2-carbonitrile: fe-999011 is the (2s,2's)-isomer
1-(2'-chloro-5'-nitrobenzenesulfonyl)-2-methylbenzimidazole: inhibits the insulin promoter
1-(2'-chlorophenyl)penta-1,4-dien-3-one: irreversibly inactivates trypanothione reductase
1-(2'-pyridyl)benzo-1,2,3-triazole: rn is from 9th ci, chem subs index; cpd not in chemline 9/9/82
1-(2'-thio-1'-hydroxyethyl)-2-(ethylphosphatidyl)isoindole: fluorescent phospholipid
1-(2, 4-dichlorophenyl)-4, 5-dihydro-5-methyl-1H-pyrazole-3,5-dicarboxylic acid diethyl ester: an herbicide safener
1-(2,1,3-benzothiadiazol-4-yl)-3-((E)-(4-hydroxyphenyl)methyleneamino)urea: anti-hiv agent
1-(2,2-dimethyl-5-hydroxy-2H-chromen-6-yl)-3-(2',3',4'-trimetho-xyphenyl)propenone: isolated from orthosiphon glabratus
1-(2,2-dimethylhept-5-eno-7-yl)-2-((hexyloxy)methyl)-7-oxabicyclo(2.2.1)heptane: ; a potent, time-dependent inhibitor of the cyclooxygenase activity of prostaglandin endoperoxide synthase
1-(2,3,4,6-tetra-O-acetyl-alpha-D-O-glucopyranosyl)-3-methyl-9H-carbazole: derivative of murrayafoline a
1-(2,3,4-trimethoxyphenyl)-3-(3-(2-chloroquinolinyl))-2-propen-1-one: an nsaid with analgesic and immunomodulatory activities
1-(2,3,6-trimethylphenyl)buta-1,3-diene: a potent grape-derived odorant in wine
1-(2,3-dibenzimidazol-2-ylpropyl)-2-methoxybenzene: a syk inhibitor with anti-inflammatory activity
1-(2,3-dichlorophenyl)-N-(pyridin-3-ylmethyl)-1H-1,2,4-triazol-5-amine: p2x7 antagonist
1-(2,3-dihydro-6-propoxychromen-4-ylideneamino)-3-(3-(4-methylpiperazin-1-yl)propyl)imidazolidine-2,4-dione: a dual blocker of i(kr) and i(ks) channels
1-(2,3-dihydroxy-4-(2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethoxy)phenyl)-2-(4-nitrophenyl)ethanone: an antibacterial against helicobacter pylori
1-(2,3-methylenedioxyphenyl)-2-aminopropane: rn given refers to cpd without isomeric designation
1-(2,4,5-trimethoxyphenyl)-1,2-dihydroxypropane: from piper clusii (piperaceae)
1-(2,4,6-trichlorophenyl)-3-methyl-O-(triazenylmethyl)glucuronic acid: urinary metabolite of 1-(2,4,6-trichlorophenyl)-3,3-
1-(2,4-dibromophenyl)-3,6,6-trimethyl-1,5,6,7-tetrahydro-4H-indazol-4-one: a kappa-opioid receptor agonist
1-(2,4-dichlorophenyl)-2-phenylpropen-1-one: structure & rn given in first source
1-(2,4-dichlorophenyl)-4-dimethylaminomethyl-1-nonen-3-one: rn given refers to hcl
1-(2,4-difluorophenethyl)-4-(4-fluorophenylsulfinyl)piperidine: a 5-ht2a receptor antagonist
1-(2,4-difluorophenethyl)-4-(4-fluorophenylsulfonyl)piperidine: a 5-ht2a receptor antagonist
1-(2,4-difluorophenyl)-4-methyl-N-(1-piperidinyl)-5-(4-(trifluoromethyl)phenyl)-1H-pyrazole-3-carboxamide: a cannabinoid 1 receptor antagonist
1-(2,4-dihydroxy-3-(2-hydroxy-3-methyl-3-butenyl)phenyl)-3-(2,2-dimethyl-2H-benzopyran-6-yl)-2-propen-1-one: from hedysarum gmelinii
1-(2,4-dihydroxy-3-(3-methyl-2-butenyl)phenyl)-3-(4-hydroxy-3-(3-methyl-2-butenyl)phenyl)-2-propen-1-one: an antileishmanial chalcone; from chinese licorice roots
1-(2,4-dihydroxy-5-(3-methylbut-2-enyl)phenyl)ethanone: from the root bark of derris indica
1-(2,4-dihydroxy-6-methoxy-3,5-bis(3-methylbut-2-en-1-yl)phenyl)ethanone: a cox-2 inhibitor; isolated from acronychia pedunculata
1-(2,4-dihydroxyphenyl)-2-bromoethanone: rn not in chemline 10/88; rn from first source; electrochemical active reagent
1-(2,4-dihydroxyphenyl)-3-(2,4-dimethoxy-3-methylphenyl)propane: from dianella ensifolia
1-(2,4-dimethoxyphenyl)-2-(3,5-dimethoxyphenyl)ethene: cyp1b1 inhibitor
1-(2,4-dimethoxyphenyl)-3-(1-methylindolyl)propenone: antimitotic
1-(2,5-dihydroxyphenyl)-2-bromoethanone: rn not in chemline 10/88; rn from first source; electrochemical active reagent
1-(2,5-dimethoxy-4-(trifluoromethyl)phenyl)-2-aminopropane: a potent serotonin 5-ht(2a/2c) agonist
1-(2,5-dimethoxyphenyl)-3-(1-naphthyl)-2-propene-1-one: has antineoplastic activity
1-(2,5-diphenylselenophen-3-yl)-3-methylpent-1-yn-3-ol: an anticonvulsant
1-(2,6,6-trimethyl-2-cyclohexen-1-yl)-2-butenone: used in skin testing for immune competence
1-(2,6-dibromo-4-isopropylphenyl)-3-(3-pyridyl)urea: a p2x4 receptor channel antagonist
1-(2,6-dichloro-4-trifluoromethylphenyl)-5-(N-(2-methylprop-2-enyl)amino)-4-trifluoromethylsulfinylpyrazole-3-carbonitrile: a pesticide
1-(2,6-diethylphenyl)imidazolidine: an octopamine receptor agonist
1-(2,6-dihydroxy-4-methoxyphenyl)-2-(4-hydroxyphenyl)ethanone: has antineoplastic activity
1-(2,6-dihydroxy-4-methoxyphenyl)hexan-1-one: analog of dif-1
1-(2,6-dihydroxyphenyl)octan-l-one: from homalomena wendlandii
1-(2,6-dihydroxyphenyl)pentan-1-one: has antineoplastic activity; isolated from cryptosporiopsis
1-(2,6-dimethylphenoxy)-3,4-dimethoxyphenylethylamino)propane: a p-glycoprotein inhibitor
1-(2,6-dimethylphenoxy)-3-(4-(2-(2-methoxyphenoxy)ethyl)piperazin-1-yl)propan-2-ol: has hypotensive and vasorelaxant activities; blocks both alpha1- and beta-adrenoceptors
1-(2,6-dimethylphenyl)-3-isobutoxyamidinourea: mf: c14-h22-n4-o2
1-(2,8-bis(trifluoromethyl)quinolin-4-yl)-2-(2-(cyclopropylamino)ethylamino)ethanol: an antimalarial
1-(2-((1-ethoxycarbonyloxyethoxycarbonylmethyl)carbamoyl)-3-phenylpropyldisulfanylmethyl)-3-methylsulfanylpropylamine: inhibits enkephalin-inactivating enzymes
1-(2-((1H-indol-5-yl)oxy)ethyl)-4,4-dimethyl-6-(pyridin-3-yl)-1,2,3,4-tetrahydroquinoline: a stat5 inhibitor with antineoplastic activity
1-(2-((2-methoxyphenyl)sulfonyl)vinyl)-2-chlorobenzene: has both antioxidant and anti-inflammatory activities
1-(2-((3-(2-(1H-indol-3-yl)ethyl)-5-(propylthio)-3H-(1,2,3)triazolo(4,5-d)pyrimidin-7-yl)amino)ethyl)-3-(pyridin-3-yl)thiourea: has antineoplastic activity
1-(2-((3-(4-fluorobenzyl)piperidin-1-yl)methyl)cyclohexyl)-3-(3-acetylphenyl)urea: a ccr3 antagonist
1-(2-((3-hydroxyadamantan-1-yl)imino)acetyl)pyrrolidine-2-carbonitrile: an impurity by-product; of vildagliptin synthesis
1-(2-(1'-neopentylspiro(indoline-3,4'-piperidine)-1-yl)phenyl)-3-(4-(trifluoromethoxy)phenyl)urea: a p2y1 antagonist
1-(2-(1-(2,3-dihydrobenzo(1,4)dioxin-2-ylmethyl)piperidin-4-yl)ethyl)-3-(2,4,6-trimethoxyphenyl)imidazolidin-2-one: an alpha(2)-adrenoceptor antagonist
1-(2-(1-(2-aminopyrimidin-4-yl)-2-((2-methoxyethyl)amino)-1H-1,3-benzodiazol-6-yl)ethynyl)cyclohexan-1-ol: inhibits group ii p21-activated kinase
1-(2-(1-(3-dimethylaminopropionyl)amino-2-methylpropyl)-4-methylphenyl)-4-(2-methyl-3-(4-chlorophenyl)propionyl)piperazine: may be useful in treating cachexia
1-(2-(1-azacyclooctanyl)-5-(trifluoromethyl))phenyl-3-nicotinoylthiourea: a protein kinase inhibitor with antiviral activity
1-(2-(18F)fluoro-3-pyridyl)-4-(2-isopropyl-1-oxo-isoindoline-5-yl)-5-methyl-1H-1,2,3-triazole: a pet ligand for imaging the metabotropic glutamate receptor type 1 in rat and monkey brains
1-(2-(1H-1,2,3,4-tetrazol-5-yl)ethyl)-5,7-dimethoxy-3-(4-methoxyphenyl)-1,2-dihydro-2-quinolinone: an antimigratory agent
1-(2-(2,4-dichlorobenzyloxy)phenyl)-2-(1H-imidazol-1-yl)ethanone: has antifungal activity
1-(2-(2,4-dichlorophenyl)-2-(4-(trifluoromethyl)benzyloxy)ethyl)-1H-imidazole: has antifungal activity
1-(2-(2,4-dichlorophenyl)-2-hydroxyethyl)-1H-imidazole: rn given refers to parent cpd; ; principal transformation product of imazalil
1-(2-(2,5-diazabicyclo(2.2.1)hept-2-yl)pyridin-4-yl)-N-pyrazin-2-yl-1H-indazol-3-amine: a spleen tyrosine kinase (syk) inhibitor
1-(2-(2-(2-(1-aminoethyl)phenyl)diselanyl)phenyl)ethanamine: an antioxidant
1-(2-(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)ethoxycarbonyloxymethyl)-4-(N'-cyano-N''-(6-(4-chlorophenoxy)hexyl)-N-guanidino)pyridinium: prodrug of chs828
1-(2-(2-(3,4-dichlorophenyl)-4-(3,4,5-trimethoxybenzoyl)morpholin-2-yl)ethyl)spiro(benzo(c)thiophene-1(3H),4'-piperidine)-2-oxide: tnra - triple neurokinin receptor antagonist
1-(2-(2-(3-(2-(naphthalen-1-yl)diazen-1-yl)phenyl)ethoxy)ethyl)piperidine-3-carboxylic acid: a photoswitchable inhibitor of gamma-aminobutyric acid transporter 1
1-(2-(2-(4-pyridyl)-2-imidazoline-1-yl)ethyl)-3-(4-carboxyphenyl)urea: rn given refers to parent cpd
1-(2-(2-(diphenyl)methoxy)ethyl)-4-(3-phenylpropyl)homopiperazine: a potent & highly selective inhibitor of dopamine transport
1-(2-(2-amino-2-methylpropanamido)-5-phenylpentanoyl)-4-(4-(1-methylethylsulfonamido)phenyl)piperazine: a peptidomimetic growth hormone secretagogue
1-(2-(2-butyryl-3-hydroxyphenoxy)-6-hydroxyphenyl)-3-hydroxybut-2-en-1-one: has antineoplastic activity; isolated from cryptosporiopsis
1-(2-(2-iodophenoxy)ethyl)-2-nitroimidazole: electron-affinic cpd for labeling hypoxic cells with 131i
1-(2-(3,4,5,6-tetrahydropyridyl))-1,3-pentadiene: inhibitor of n-methyltransferases produced by actinomycetes
1-(2-(3,4-dihydro-6,7-dimethyl-2-naphthalenyl)ethyl) pyrrolidine fumarate: a sigma receptor ligand
1-(2-(3-(2-chloroethyl)-3-nitrosoureido)ethyl)-3,4-dimethoxy-benzene: anti-tumor agent
1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole: inhibits platelet aggregation & ca2+ entry into platelets
1-(2-(3-iodo-4-aminophenyl)ethyl)-4-(3-(trifluoromethyl)phenyl)piperazine: structure & rn given in first source
1-(2-(3-methoxyphenyl)ethyl)phenoxy-3-(dimethylamino)-2-propanol: metabolite of mci-9042
1-(2-(3-methyl-5-benzyloxyindolyl)carbonyl)-2-isopropyl hydrazide: irreversibly inhibits mouse brain type a mao
1-(2-(4-(4-acetylphenyl)piperazin-1-yl)-2-oxoethyl)-N-(3-chloro-4-hydroxyphenyl)pyrrolidine-3-carboxamide: inhibits both erk1 and erk2
1-(2-(4-(4-fluorobenzyl)-4-hydroxypiperidin-1-yl)ethyl)-3-(thieno(3,2-b)pyridin-7-yl)urea: a urotensin-ii receptor antagonist
1-(2-(4-benzyl-4-hydroxypiperidin-1-yl)ethyl)-3-(2-methylquinolin-4-yl)urea: a urotensin-ii receptor antagonist
1-(2-(4-chlorophenyl)cyclopropylmethoxy)-3,4-dihydroxy-5-(3-imidazo(4,5-b)pyridin-1-yl-3-phenylacryloyloxy)cyclohexanecarboxylic acid: glucose-6-phosphate translocase inhibitor
1-(2-(4-cyclobutyl-(1,4)diazepane-1-carbonyl)-4-(3-fluorophenoxy)pyrrolidin-1-yl)ethanone: a histamine h3 receptor antagonist
1-(2-(4-ethyl-2,3-dioxo-1-piperaziny)ethyl)-3-methylurea: has antitumor activity against solid form ehrlich carcinoma
1-(2-(4-fluorophenyl)-2-(4-methylpiperazin-1-yl)ethyl)-4-(4-(1naphthyl)butyl)piperazine: a mc4 receptor antagonist and serotonin reuptake inhibitor
1-(2-(4-nitrophenoxy)acetyl)pyrrolidin-2-one: antiamnesic agent
1-(2-(4-trifluoromethylphenyl)-4-n-propyl-1,3-dioxolan-2-ylmethyl)-1H-1,2,4-triazole: inhibits brassinosteroid biosynthesis
1-(2-(5-fluoro-2-methoxyphenyl)cyclopropyl)-N-(2-methoxybenzyl)methanamine: a serotonin 2c receptor agonist with antipsychotic activity
1-(2-(6-azaphenanthrene-1,10-dicarboximido)propylamino)-2-(2-(3-nitronaphthalene-1,8-dicarboximido)propylamino)ethane: xp-315 is the dihydromethanesulfonate salt
1-(2-(9-octadecenoyloxy)ethyl)-2-(8-heptadecenyl)-3-(hydroxyethyl)imidazolinium: cationic lipid used to complex with dna as an expression vector for delivering genes in vivo
1-(2-(N-phenylbenzenesulfonamido)ethyl)-1H-1,2,3-triazole-4,5-dicarboxylic acid: inhibits prostaglandin e synthase-1
1-(2-(R)-(1-(R)-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(R)-(3,4-difluorophenyl)-4-(R)-tetrahydro-2H-pyran-4-ylmethyl)-3-(R)-methylpiperidine-3-carboxylic acid: nk(1) receptor antagonist
1-(2-(benzo(d)(1,3)dioxol-6-yl)ethyl)-4-(2-methoxyphenyl)piperazine: an antagonist of alpha-1a and alpha-1d adrenergic receptors
1-(2-(decylthio)ethyl)azacyclopentane-2-one: used as a penetration enhancer for topical applications
1-(2-(diphenylmethoxy)ethyl)-4-(3-phenyl-2-propenyl)piperazine: dopamine uptake inhibitor and indirect dopamine agonist
1-(2-(diphenyloxy)ethyl)-4-(3-phenylallyl)piperazine: dopamine uptake inhibitor
1-(2-(dodecyloxy)ethyl)pyrrolidine hydrochloride: active against ascaris lumbricoides suum
1-(2-(hydroxymethyl)-1,3-dioxolan-4-yl)5-vinylpyrimidine-2,4(1H,3H)-dione: an antiviral
1-(2-(hydroxymethyl)-1,3-dioxolan-5-yl)-5-(2-iodovinyl)uracil: active against varicella zoster virus
1-(2-(imidazol-4-yl)ethylamino)-4-chloro-8-nitrophthalazine: has trypanocidal activity
1-(2-(isoxazol-3-yl)-1H-imidazol-4-yl)butane-1,2,3,4-tetraol: inhibits sphingosine-1-phosphate lyase
1-(2-(tris(4-methoxyphenyl)methoxy)ethyl)-3-piperidinecarboxylic acid: selective inhibitor of gaba transporter 3 (gat-3)
1-(2-adamantyl)-3-(2,3,4-trifluorophenyl)urea: an antitubercular agent
1-(2-allylphenoxy)-3-((1-amino-4-menthane-8-yl)amino)-2-propanol: alprenolol analog; isopropylamino residue of alprenolol replaced by 1,8-diamino-p-menthane moiety in the 8 position
1-(2-allylphenoxy)-3-((1-bromoacetylamino-4-menthane-8-yl)amino)-2-propanol: alprenolol analog; isopropylamino group of alprenolol replaced by 1-bromoacetylamino-8-amino-p-menthane moiety in the 8 position
1-(2-allylphenoxy)-3-((8-amino-4-menthane-1-yl)amino)-2-propanol: alprenolol analog; isopropylamino residue of alprenolol was replaced by 1,8-diamino-p-menthane moiety in the 1 position
1-(2-allylphenoxy)-3-((8-bromoacetylamino-4-menthane-1-yl)amino)-1-propanol: irreversibly inactivates the dihydroalprenolol binding site; alprenolol analog; isopropylamino group of alprenolol replaced by 8-bromoacetylamino-1-amino-p-menthane moiety in the 1 position
1-(2-amino-1-(1-(naphthyloxy)methyl)ethyl)piperidine: inhibitor of serotonin; rn given refers to hcl
1-(2-amino-2-oxoethyl)-4-(2-(1,1-dioxido-2H-naphtho(1,8-cd)isothiazol-6-yl)ethyl)-1,4-diazoniabicyclo(2.2.2)octane: a pbp2a-binding, anti-mrsa pharmacophore
1-(2-amino-4-(5-nitro-2-furyl)-2-thiazolyl)-1-deoxyglucopyranuronic acid: metabolite of 2-amino-4-(5-nitro-2-furyl)thiazole (anft)
1-(2-amino-4-methanesulfonamidophenoxy)-2-(N-(3,4-dimethoxyphenethyl)-N-methylamino)ethane: a class iii antiarrhythmic agent
1-(2-aminoacetyl)-4-benzamidopyrrolidine-2-carboxylic acid: an antiarrhythmia agent
1-(2-aminobenzoyl)-3-(4-(5-bromopyrimidin-2-ylsulfanyl)phenyl)urea: has antineoplastic activity
1-(2-aminoethyl)-2-(piperidin-4-yl)-1H-benzo(d)imidazole-5-carboxamide: a janus kinase 1 inhibitor
1-(2-aminoethyl-(6-hydrazinopyridine-3-carbamidyl))-3,5-bis-(2-fluorobenzylidene)-4-piperidone: has antineoplastic activity
1-(2-aminonaphth-1-yl)-2-naphthol: a chiral catalyst
1-(2-aminopropyl)-1H-indazol-6-ol: has ocular hypotensive activity
1-(2-aminopropyl)-1H-indazole-6-ol: al-34462 is the (s)-isomer; an antihypertensive agent
1-(2-aminopropyl)-8,9-dihydropyrano(3,2-e)indole: a selective 5-ht2 receptor agonist with ocular hypotensive activity
1-(2-aminopyridin-4-ylmethyl)-6-(3,5-dimethylbenzoyl)-5-isopropyl-1H-pyrimidine-2,4-dione: an anti-hiv agent
1-(2-benzoxazolyl)-3,3,3-trifluoro-2-propanone: exhibited the potent antibacterial activity against helicobacter pylori, but had no urease activity
1-(2-benzoylethyl)pyridinium: ; rn given is for chloride
1-(2-benzyl-1,3-dioxoisoindolin-5-yl)-3-(1-phenylethyl)thiourea: a chemosensor for colorimetric detection of anions
1-(2-biphenyl)-4-(2-(3-methoxyphenyl)ethyl)piperazine: a 5-ht7 receptor ligand
1-(2-bromo-3,4,5-trimethoxyphenyl)-3-(3-hydroxy-4-methoxyphenylamino)prop-2-en-1-one: a microtubule-stabilizing agent
1-(2-bromophenyl)-3-(7-cyano-3H-benzotriazol-4-yl)urea: a cxcr2 inverse agonist
1-(2-carboxy-3-chlorophenyl)pyrrole: hypoglycemic agent in rats
1-(2-chloro-2-phenylethyl)-3-(4-methylphenyl)-1H-pyrazolo(3,4-d)pyrimidin-4-amine: a fyn kinase inhibitor with antineoplastic activity; also inhibits phosphorylation of tau protein
1-(2-chloro-2-phenylethyl)-6-(methylthio)-N-(2-phenylethyl)-1H-pyrazolo(3,4-d)pyrimidin-4-amine: has antineoplastic activity
1-(2-chloro-4-methylphenyl)-7-methyl-5-(1-propylbutyl)-1,3,4,5-tetrahydro-1,5,8-triazaacenaphthylene: a crf(1) receptor antagonist
1-(2-chloro-6-fluorophenyl)-5-methylindolin-2-one: an anti-inflammatory with reduced gastric ulceration
1-(2-chlorobenzyl)-2-(1-(4-isobutylphenyl)ethyl)-1H-benzimidazole: targets 5-lipoxygenase-activating protein to inhibit leukotriene biosynthesis
1-(2-chlorobenzyl)-5'-phenyl-3'H-spiro(indoline-3,2'-(1,3,4)thiadiazol)-2-one: stimulates carp-1 expression
1-(2-chloroethoxycarbonylmethyl)-4-naphthalenesulfonic acid calcium salt: auxin physiological analog
1-(2-chloroethyl)-1-nitroso-3-(methylene-2-pyridinyl)urea: rn given refers to parent cpd
1-(2-chloroethyl)-1-nitrosocarbamoylalanine estradiol-17-ester: rn refers to (l-ala)-(17-beta)-isomer
1-(2-chloroethyl)-3-(1-oxyl-2,2,6,6-tetramethylpiperidinyl)-1-nitrosourea: has more antineoplastic activity & less toxicity than ccnu
1-(2-chloroethyl)-3-(2-(5-fluoro-3-oxobenzoselenazol-2(3H)-yl)ethyl)-1-nitrosourea: has antineoplastic activity
1-(2-chlorophenyl)-N-(1-methylpropyl)-N-(4-butyl-(N,N-dimethylamino)-3-isoquinolinecarboxamide)methyl iodide: benzodiazepine receptor ligand
1-(2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl)-4-ethynylimidazole: an anti-inflammatory and cytoprotective agent
1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole: enhances transforming growth factor beta/smad signaling
1-(2-cyclohex-2-enylpropionyl)-3-methylurea: structure in first soure
1-(2-cyclohexylethyl)-3-(2-methoxyphenylacetyl)indole: a synthetic cannabinoid and designer drug
1-(2-cyclopropylethyl)-3-(1,1-dioxo-2H-1,2,4-benzothiadiazin-3-yl)-6-fluoro-4-hydroxy-2(1H)-quinolinone: inhibits hepatitis c virus rna-dependent rna polymerase
1-(2-deoxy-2-fluoro-3-O-(1-methyl-1,4-dihydropyridyl-3-carbonyl)ribofuranosyl)-5-(2-iodovinyl)uracil: ; ivfru coupled to a salt redox delivery system to increase diffusion into central nervous system
1-(2-deoxy-beta-L-erythropentafuranosyl)-5-methyl-2,4(1H)-pyrimidinone: has an activity against hepatitis b virus
1-(2-deoxy-beta-ribofuranosyl)-5-bromo-2-pyrimidinone: rn & ; rn given refers to erythro-(d)-isomer; rn for cpd without isomeric desigantion not in chemline 8/85
1-(2-dimethylaminoethoxicarbonylmethyl)naphthalene chlormethylate: auxin physiological analog
1-(2-dimethylaminoethyl)-3-(2,3-di(tetradecoxy)propyl)urea: used in niosomes for gene delivery
1-(2-ethoxyphenyl)-4-(3-(3-thiophen-2-ylisoxazolin-5-yl)propyl)piperazine: a dopamine d3 receptor antagonist
1-(2-fluorenyl)ethenylspiro(1,2,4-trioxane-3,2'-adamantane): an antimalarial
1-(2-fluoro-3-hydroxy-4-(hydroxymethyl)-2-methylcyclopentyl)pyrimidine-2,4(1H,3H)-dione: inhibits ns5b polymerase from hepatitis c virus
1-(2-fluoro-4-(1H-pyrazol-1-yl)phenyl)-5-methoxy-3-(1-phenyl-1H-pyrazol-5-yl)pyridazin-4(1H)-one: an inhibitor of phosphodiesterase 10a
1-(2-fluoro-5-methoxy-3'-(trifluoromethyl)-(1,1'-biphenyl)-4-yl)-N-(isoxazol-3-yl)isoquinoline-6-sulfonamide: a na(v)1.7 channel inhibitor
1-(2-fluoroethyl)-2-nitroimidazole: potential in vivo marker of hypoxic tissue
1-(2-fluoroethyl)-4-((4-cyanophenoxy)methyl)piperidine: a sigma-1 receptor radioligand
1-(2-fluoroethyl)-4-(4-N,N-dimethylaminostyryl)-1H-1,2,3-triazole: for imaging beta-amyloid plaques
1-(2-fluorophenyl)-3-(2-oxo-5-phenyl-2,3-dihydro-1H-benzo(e)(1,4)diazepin-3-yl)urea: an antiviral agent against respiratory syncytial virus
1-(2-furyl)-3-(2-furyl)-2-propen-1-one: has antifungal activity
1-(2-furyl)pentacosa-16,18-diyne: isolated from polyalthia suberosa
1-(2-hydroxy-2-methylpropyl)-N-(5-(7-methoxyquinolin-4-yloxy)pyridin-2-yl)-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide: a c-met inhibitor
1-(2-hydroxy-2-phenylethyl)-3,5-diphenylpyrazole: starting material for cpds with cns depressant & platelet aggregation activity
1-(2-hydroxy-3- methyl 4,5-dimethoxyphenyl)-3-(1H-pyrrol-2-yl)-2-propen-1-one: from glycosmis pentaphylla
1-(2-hydroxy-3-(4-phenyl-1-piperazinyl)propyl)pyrrolidin-2-one: has antiarrhythmic and hypotensive activities
1-(2-hydroxy-3-nonyl)-1,2,4-triazole: rn refers to ((r*,s*)-(+-))-isomer; potent adenosine deaminase inhibitor
1-(2-hydroxy-4-morpholin-4-ylphenyl)ethanone: a dna-dependent protein kinase inhibitor
1-(2-hydroxy-5-methylphenyl)-3,5-dioxo-1H-imidazo(3,4-b)isoindole: a proton transfer probe
1-(2-hydroxybenzylidene)-4-phenylsemicarbazide: is also called flurescent receptor 1
1-(2-hydroxyethoxy)methyl-2-methyl-3-hydroxyl-4-pyridinone: a targeted, bifunctional chelating agent for potential uranic detoxification in the kidney
1-(2-hydroxyethyl)-2-methyl-5-nitroimidazole N-(5-carboxy-5-aminopentane)carbamate: rn given for (dl)-isomer
1-(2-hydroxyethyl)-3,5,7-triaza-1-azoniatricyclo(3.3.1.1(3,7))decane bromide: focal adhesion kinase (fak) inhibitor
1-(2-hydroxyethyl)-3-(6-(2-methoxyphenyl)benzo(d)thiazol-2-yl)urea: a bcr-abl tyrosine kinase inhibitor
1-(2-hydroxyethyl)-3-nitro-4-pyrazolecarboxamide: active against both gram-positive & gram-negative bacteria
1-(2-hydroxyphenyl)-3-(4-methylphenyl)prop-2-en-1-one: has antimalarial, antileishmanial, and antioxidant activities
1-(2-hydroxyphenylamino)-1-deoxy-gentiobioside 1,2-carbamate: from corn roots
1-(2-iodophenyl)-4-cyano-5-(4-methoxyphenyl)-N-(piperidin-1-yl)-1H-pyrazole-3-carboxylate: a cb1 receptor ligand
1-(2-isopropoxyphenyl)-4-((2-oxopiperidin-1-yl)acetamido)propylpiperazine: an alpha(1)-adrenergic receptor antagonist
1-(2-methoxy-5-(3-phenylpropyl))-2-aminopropane: a 5-ht(2a) serotonin receptor antagonist
1-(2-methoxybenzylidene)-4-phenylsemicarbazide: is also called flurescent receptor 2
1-(2-methoxybenzylidene)-4-phenylthiosemicarbazide: a fluorescent chemodosimeter
1-(2-methoxyphenyl)-4-(2-(3,4-dimethoxyphenyl)ethyl)piperazine: for treatment of benign prostatic hyperplasia
1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine: rn from toxlit
1-(2-methoxyphenyl)-4-(4--(2-phthalimido)cyclohexyl)piperazine: a 5-ht(1a) receptor antagonist
1-(2-methoxyphenyl)piperazine: rn given refers to parent cpd
1-(2-methyl-4-methoxyphenyl)-4-((2-hydroxyethyl)amino)-6-trifluoromethoxy-2,3-dihydropyrrolo(3,2-c)quinoline: inhibitor of potassium hydrogen atpase
1-(2-methyl-4-pyrimidinyl)-4-(1-(4-bromophenylsulfonyl)piperazin-4-ylcarbonyl)piperidine: inhibits 2,3-oxidosqualene cyclase-lanosterol synthase
1-(2-methyl-6-benzothiazolyl)-3-(N-benzyl-4-piperidinyl)propan-1-one: rn refers to hcl; a selective acetylcholinesterase inhibitor
1-(2-methylbenzoxazol-6-yl)-3-(1,5)naphthyridin-4-yl urea: selective ox1 receptor antagonist
1-(2-methylphenyl)-4-methylamino-6-methyl-2,3-dihydropyrrolo(3,2-c)quinoline: a k+-competitive fluorescent inhibitor of the h,k-atpase
1-(2-naphthylmethyl)-4-benzylpiperazine: a sigma selective ligand
1-(2-nitrophenyl)diazoethane: used to place 1-(2-nitrophenyl)ethyl residues on hemoglobin
1-(2-nitrophenyl)ethylpyranine: a caged fluorophore
1-(2-phenethyl)-4-(2-pyridyl)piperazine: a sigma2 receptor antagonist
1-(2-phenethyl)imidazo(1,2-a)quinoxalin-4-amine: metabolite of eapb0203
1-(2-phenyl-2-hydroxyiminoethyl)-1-(4-methylquinolinium): rn given refers to chloride
1-(2-phenyl-2-hydroxyiminoethyl)-1-(6-methylquinolinium): rn given refers to chloride
1-(2-phenylbutyryl)-3-methylurea: induces cytochrome p-450-dependent fatty acid monooxygenase in bacillus megaterium
1-(2-phosphonylmethoxyethyl)cytosine: a phosphonylmethoxyalkylpyrimidine
1-(2-pyridylmethylidene)-5-(salicylidene)thiocarbonylhydrazone: reagent for spectrophotometric determination of palladium
1-(2-pyrimidinyl)-4-imino-1,4-dihydropyridine: rn given refers to parent cpd
1-(2-pyrrolidinylcarbonyl)-2-pyrrolidinylboronic acid: a dipeptidyl peptidase iv inhibitor; rn given refers to compound with no isomeric designation
1-(2-thiazolylazo)-2-naphthol: used to locate cadmium not bound to metallothionein
1-(2-thienyl)-2-(methylamino)propane: thiophene analog of methamphetamine
1-(2-trifluoromethoxyphenyl)-2-nitroethanone: a hepatotoxic compound
1-(2-trifluoromethylphenyl)imidazole: an inhibitor of neuronal nitric oxide synthase in mouse
1-(3',3'-diphenylpropyl)-4-(2'-(2'',4''-dichlorophenyl)ethyl)-7-(N-aminocarbonylmethyl-N-(2-(2'',4''-dichlorophenyl)ethyl)aminocarbonyl)perhydro-1,4-diazepine-2,5-dione: an apaf-1 inhibitor with mitochondrioprotective activity
1-(3',4',5'-trimethoxy)phenylnaphtho(2,1b)furan: an anticancer agent
1-(3',4',5'-trimethoxyphenyl)-3-(3'',4''-dimethoxy-2'-hydroxyphenyl)propane: a microtubule-depolymerizing agent with antineoplastic activity
1-(3',4'-dichloro-2-fluoro(1,1'-biphenyl)-4-yl)cyclopropanecarboxylic acid: a beta-amyloid(1-42) lowering agent
1-(3',4'-dihydroxycinnamoyl)cyclopentane-2,3-diol: from the amazonian tree chimarrhis turbinata
1-(3',5'-dihydroxy)phenyl-2-(4''-O-beta-D-glucopyranosyl)phenylethane: from leaves of camellia oleifera abel
1-(3',5'-dihydroxy-4'-methoxyphenyl)-7-phenyl-3-heptanone: from the fruits of alpinia oxyphylla
1-(3',5'-dihydroxyphenoxy)-7-(2'',4'',6''-trihydroxyphenoxy)-2,4,9-trihydroxydibenzo-1,4,-dioxin: isolated from ecklonia cava
1-(3',5'-dihydroxyphenoxy)-7-(2',4',6-trihydroxyphenoxy)-2,4,9-trihydroxydibenzo-1,4-dioxin: isolated from eclonia cava
1-(3',5'-dimetoxy)phenyl-2-(4''-O-beta-D-glucopyranosyl(6-1)-O-alpha-L-rhamnopyranosyl)phenylethane: from leaves of camellia oleifera abel
1-(3',5'-dimetoxy)phenyl-2-(4''-O-beta-D-glucopyranosyl)phenylethane: from leaves of camellia oleifera abel
1-(3'-(myristoyloxy)propyl)diethylenetriamine-1,4,7,7-tetraacetic acid gadolinium complex: lipophilic fatty acyl conjugated nmr contrast agent
1-(3'-amino-3'-carboxypropyl)adenine: ; rn given is for (+-)-isomer
1-(3'-amino-3'-carboxypropyl)uracil: ; rn given is for (s)-isomer
1-(3'-iodophenyl)-3-methy-2-pyrazolin-5-one: ; methyl is spelled as methy throughout
1-(3'-methoxypropanoy)-2,4,5-trimethoxy benzene: anitfungal and larvicidal compund from the root bark of cordia alliodora
1-(3'-nido-carboranyl-2'-hydroxy)propyl-2-nitroimidazole: used in boron neutron capture therapy
1-(3'beta-hydroxy-28'-propylcarboxy-urs-12'ene)-4-(3''beta-hydroxy-lup-20''(29'')ene-28''-methylcarboxy)-1,2,3-triazole: synthetic antineoplastic
1-(3,.4-dimethoxyphenyl)-3,5-dodecenedione: has antineoplastic activity
1-(3,4,5-trihydroxyphenyl)nonan-1-one: a ligand for tr3 orphan nuclear receptor
1-(3,4,5-trimethoxyphenyl)-5-(4-ethoxyphenyl)-1H-1,2,4-triazole: has antineoplastic activity
1-(3,4,5-trimethoxyphenyl)-5-(4-ethoxyphenyl)-1H-tetrazole: has antineoplastic activity
1-(3,4-dichlorobenzyl)-3,4,5,6-tetrahydro-2(1H)-pyrimidone: anti-depressant with anti-anxiety activity
1-(3,4-dichlorobenzyl)-N-(2-morpholinoethyl)-1H-1,2,3-triazol-4-amine: a sigma 1 receptor antagonist with antinociceptive activity
1-(3,4-dichlorophenyl)-2-(2-imino-3-(4-methylbenzyl)-2,3-dihydro-1H-benzo(d)imidazol-1-yl)ethan-1-ol: an agonist of orexin receptors
1-(3,4-dichlorophenyl)-2-pyrrolidin-1-ylpentan-1-one: a monoamine uptake inhibitor
1-(3,4-dichlorophenyl)-3-azabicyclo-(3.1.0)hexane hydrochloride: a triple uptake inhibitor
1-(3,4-dichlorophenyl)-4-((dimethylamino)methyl) 1-nonen-3-one: rn given refers to hcl
1-(3,4-dichlorophenyl)-6-(methoxymethyl)-4-azabicyclo(4.1.0)heptane: a triple reuptake inhibitor for serotonin, norepinephrine, and dopamine
1-(3,4-dichlorophenyl)-N,N-dimethyl-1,2,3,4-tetrahydroquinolin-4-amine: a dual serotonin and dopamine reuptake inhibitor
1-(3,4-dichlorophenyl)acetyl-2-(1-pyrrolidinyl)methylpiperidine: brl-52537 is the (+-)-isomer
1-(3,4-dihydro-4-hydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)ethanone: has cytoprotective activity; isolated from tussilago farfara
1-(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)-3,3-dimethyl-2-((4-pyridinylmethyl)amino)-1-butanone: a hypocretin receptor 2 antagonist
1-(3,4-dihydroxybenzoyl)-3-hydroxy-6,7-dihydroxyisoquinoline: inhibits binding of insulin-like growth factor to igfbp-3
1-(3,4-dihydroxybenzoyl)-3-hydroxycarbonyl-6,7-dihydroxyisoquinoline: inhibits binding of insulin-like growth factor to igfbp-3
1-(3,4-dihydroxyphenyl)-2-(3-(4-carbamylphenyl)-1-methylpropylamino)ethanol: gp-2-114 is a 50:50 mixture of (rr)- and (rs)- isomers; do not confuse with gp 128 (thrombospondin)
1-(3,4-dihydroxyphenyl)-2-(n-propylamino)propane: intermediate in n-propylamphetamine metabolism; rn given refers to parent cpd
1-(3,4-dihydroxyphenyl)-2-thiocyanate-ethanone: a molecular chaperone inducer that protects neurons from er stress
1-(3,4-dihydroxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one: has anti-inflammatory activity
1-(3,4-dihydroxystyryl)-3-(4-hydroxyphenethyl)urea: an nsaid
1-(3,4-dimethoxy-2--chlorobenzylideneamino)guanidine: cardioprotective product of the xanthine oxidase-catalyzed reduction of pr5 cpd
1-(3,4-dimethoxy-2-chlorobenzylideneamino)-3-hydroxyguanidine: alternative electron acceptor for xanthine oxidase
1-(3,4-dimethoxybenzyl)-5-(2-(methylsulfonyl)-6-(trifluoromethyl)pyrimidin-4-yl)pyridin-2(1H)-one: a neuroprotective agent that binds succinate dehydrogenase subunit b to prevent bim-induced apoptosis
1-(3,4-dimethoxyphenyl)-3-(9H-pyrido(3,4-b)indol-1-yl)prop-2-en-1-one: an mdm2 inhibitor with antineoplastic activity; structure in first soruce
1-(3,4-dimethoxyphenyl)-3-dodecanone: enhances uptake of calcium by sarcoplasmic reticulum
1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)-1H-benzotriazole-5-carboxylic acid: a partial rxr agonist
1-(3,5-bis(trifluoromethyl)phenyl)-3-(4-bromo-2-(1H-tetrazol-5-yl)phenyl)thiourea: activates calcium-activated big-conductance potassium channels
1-(3,5-bis-trifluoromethylphenyl)-3-(2,4-dibromo-6-(1H-tetrazol-5-yl)phenyl)urea: membrane transport modulator and potassium channel agonist
1-(3,5-di-tert-butyl-4-hydroxyphenyl)-2-(2-((3-hydroxypropyl)amino)-5,6-dimethyl-1H-benzo(d)imidazol-1-yl)ethanone: inhibits nf-kappab activation
1-(3,5-dichloro-2,4,6-trihydroxyphenyl)hexane-1-one: a differentiation inducing factor isolated from dictyostelium discoideum
1-(3,5-dichloro-2,6-dihdyroxy-2-methoxyphenyl)hexan-1-one: analog of dif-1
1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl-)-1-pentanone: ; endogenous differention-inducing factor; induces stalk-cell differentiation in the cellular slime mold dictyostelium discoideum
1-(3,5-dichloropyrid-4-ylmethyl)-5-cyclopentoxy-6-methoxyphthalazine: a pde4 inhibitor
1-(3,5-dihydroxyphenyl)heptan-1-one: from ardisia virens
1-(3,5-dihydroxyphenyl)pentadecan-1-one: from ardisia virens
1-(3,5-dimethyl-1H-pyrazol-4-yl)ethanone: inhibits opsin regeneration
1-(3,5-dimethyl-4-propionylamino)benzoyl-4-(N-methyl-2-phenylethyl)aminopiperidine: a canine hindlimb vasodilator
1-(3-((4-(2-isopropoxyphenyl)-1-piperidinyl)methyl)-benzoyl)piperidine hydrochloride: has 5-ht1a receptor affinity
1-(3-((4-(4-acetylphenyl)piperazin-1-yl)methyl)-4-hydroxy-5-methoxyphenyl)-3-(pyridin-3-yl)prop-2-en-1-one: induces apoptosis signaling
1-(3-(1-((4-fluorophenyl)methyl)-7,8-dihydro-8-oxo-1H-imidazo(4,5-g)quinazolin-6-yl)-4-propoxyphenyl)carboxamide: a pde5 inhibitor that may prove useful in treating erectile dysfunction
1-(3-(1-(2,6-dihydroxyphenyl)butyl)-2,6-dihydroxyphenyl)octan-l-one: from homalomena wendlandii
1-(3-(1-methyl-1H-pyrazol-4-yl)-5-oxo-5H-benzo(4,5)cyclohepta(1,2-b)pyridin-7-yl)-N-(pyridin-2-ylmethyl)methanesulfonamide: inhibits both ron and c-met kinases
1-(3-(1H-imidazol-1-yl)propyl)-3-(3,4,5-trimethoxyphenyl)thiourea: a glutaminyl cyclase inhibitor
1-(3-(1H-imidazol-1-yl)propyl)-4-benzoyl-5-(4-bromophenyl)-3-isopropoxy-1H-pyrrol-2(5H)-one: antineoplastic agent that inhibits the interaction between p53 and mdm2 protein
1-(3-(2-(4-(2-methyl-5-quinolinyl)-1-piperazinyl)ethyl)phenyl)-2-imidazolidinone: antagonist of 5-ht1a, 5-ht1b, and 5-ht1d receptors
1-(3-(2-chlorophenoxy)propyl)-1H-indole-3-carbonitrile: inhibits androgen receptor transactivation
1-(3-(2-fluoropyridin-3-yloxy)propyl)pyrrole-2,5-dione: a peptide radiolabeling agent
1-(3-(2-furanyl)propyl)-3,4-dimethyl-4-(3-hydroxyphenyl)piperidine: has high affinity & antagonist activity for both mu & kappa receptors
1-(3-(2-hydroxyl-3-piperidin-1-yl-propoxy)-phenoxy)-3-piperidin-1-ylpropan-2-ol: inhibitor of sars-cov and sars-cov-2 viral entry
1-(3-(2-indanylacetyl)-L-thioprolyl)pyrrolidine: a prolyl endopeptidase inhibitor
1-(3-(2-methylpyridin-4-yl)-1H-pyrazolo(4,3-c)pyridin-6-yl)-3-(1-phenylethyl)urea: an extracellular signal-regulated kinase inhibitor
1-(3-(2H-1,2,3-triazol-2-yl)phenyl)-N-6-(2-aminocyclohexyl)-1H-pyrazolo(3,4-b)pyrazine-3,6-diamine: a spleen tyrosine kinase inhibitor
1-(3-(3,4,5-trimethoxyphenyl)acryloyl)piperidin-2-one: an nrf2 activator
1-(3-(3-(3,4,5-trimethoxybenzoyl)-1H-pyrrol-1-yl)phenyl)guanidine: a tubulin polymerization inhibitor with antineoplastic activity
1-(3-(3-(4-acetylpiperazin-1-yl)propyl)-7-fluoro-3-phenyl-3a,4-dihydro-3H-pyrazolo(5,1-c)(1,4)benzoxazin-2-yl)ethanone: inhibits mitotic kinesin spindle protein
1-(3-(3-(aminoiminomethyl)phenyl)-2-((2-naphthalenylsulfonyl)amino)-1-oxopropyl)-4-methylpiperidine: rn given for (s)-isomer
1-(3-(3-aminopropylamino)-2-hydroxylpropylamino)-9,10-anthraquinone: has antineoplastic activity
1-(3-(3-fluorophenyl)-3-(1,2,3,4-tetrahydronaphthalene-4-carboxamido)propanamido)-3-methylbutyl boronic acid: a proteasome inhibitor
1-(3-(3-methyl-2-butenyl)-2,4-(dihydroxy)phenyl)-3-(2,2-dimethyl-8-hydroxy-2H-benzopyran-6-yl)-2-propen-1-one: an antileishmanial chalcone; from chinese licorice roots
1-(3-(4-(1,1-dimethylpropyl)phenoxy)propyl)piperidine: an h3 histamine receptor antagonist
1-(3-(4-(3-chlorophenyl)-1-piperazinyl)propyl)-3,4-dihydro-5-methoxy-2(1H)-quinolinone: sigmoid receptor agonist
1-(3-(4-(o-tolyl)piperazin-1-yl)propyl)pyrrolidin-2-one: a non-selective alpha-adrenoceptor antagonist
1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo(3,4-d)pyrimidin-1-yl)piperidin-1-yl)-2-(dimethylamino)ethanone: an flt3 kinase inhibitor
1-(3-(4-aminobutylamino)-2-hydroxylpropylamino)-9,10-anthraquinone: has antineoplastic activity
1-(3-(4-chlorophenyl)-5-(3,5-dibromo-2-hydroxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)ethanone: a braf kinase inhibitor
1-(3-(4-methoxyphenyl)acryloyl)pyrrolidin-2-one: an nrf2 activator
1-(3-(4-octylphenoxy)-2-oxopropyl)indole-5-carboxylic acid: cpla2-alpha inhibitor
1-(3-(4-phenoxyphenoxy)-2-oxopropyl)indole-5-carboxylic acid: a phospholipase a2alpha inhibitor
1-(3-(4-tert-butylphenoxy)propyl)-4-piperidino-piperidine: a histamine h3 receptor ligand
1-(3-(4-tert-butylphenoxy)propyl)piperidine: a histamine h3 antagonist
1-(3-(4-tert-pentylphenoxy)propyl)piperidine: a histamine h3 receptor antagonist
1-(3-(5-(1,2,4-triazol-4-yl)-1H-indol-3-yl)propyl)-4-(2-(3-fluorophenyl)ethyl)piperazine: an h5-ht(1d) receptor agonist
1-(3-(N-(methoxycarbonyl)amino)-3-phenylpropanoyl)-4-((2-methyl-3-pyridyl)cyanomethyl)piperazine: paf antagonist
1-(3-(aminomethyl)phenyl)-N-(3-fluoro-2'-(methylsulfonyl)(1,1'-biphenyl)-4-yl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide: dpc423 is the hcl salt
1-(3-(azidomethyl)-2,3-dideoxy-5-O-phosphorylpentofuranoyl)thymine: a thymidine monophosphate kinase inhibitor
1-(3-(benzyloxy)pyrazin-2-yl)-3-(3,4-dichlorophenyl)urea: blocks beta-amyloid-induced opening of mitochondrial permeability transition pore (mptp)
1-(3-(diisopropylcarbamoyl)-2-phenyl-3-(pyridin-3-yl)propyl)-3-(2-fluorobenzyl)urea: a kv1.5 potassium channel antagonist
1-(3-(fluoresceinylthioureidoalanyl-alanyl-alanyl-L-leucyl-glycyl-L-norvalyl-L-prolylamino)propylamino)anthracene-9,10-dione: a prodrug that becomes fluorescent after cleavage by mmp-9
1-(3-(imidazol-1-yl)propylamino)-4-chlorophthalazine: a trypanocidal agent that inhibits iron superoxide dismutase
1-(3-(methylamino)-1-phenylpropyl)-3-phenyl-1H-benzo(d)imidazol-2(3H)-one: a pet tracer for the norepinephrine transporter
1-(3-(methylamino)-propyl)-5-methyl-3-phenyl-1H-indazole: non-tricyclic antidepressants
1-(3-(trifluoromethyl)pyridin-2-yl)-N-(4-(trifluoromethylsulfonyl)phenyl)-1,2,3,6-tetrahydropyridine-4-carboxamide: a trpv1 antagonist
1-(3-amino-4-(4-(tert-butyl)phenyl)-6-(p-tolyl)furo(2,3-b)pyridin-2-yl)ethan-1-one: furopyridine compound with fluorescent and antioxidant properties
1-(3-aminopropyl) piperazine-4-aminoamide: a ccr5 antagonist and hiv-1 entry inhibitor
1-(3-aminopropyl)-3-butylimidazolium: used to derivatize carboxy groups on peptides
1-(3-astatobenzyl)guanidine: ; might prove useful for treating neuroblastoma
1-(3-bromo-4,5-dimethoxyphenyl)-5-chloro-3-(4-(2-hydroxyethyl)-1-piperazinylcarbonyl)-2-(methoxycarbonyl)naphthalene: a phosphodiesterase 5 inhibitor
1-(3-carbamoylpyridinium)-4-(4-hydroxyiminomethylpyridinium)-but-2-ene: nerve agent antidote
1-(3-chloro-2,4,6-trihydroxyphenyl)hexan-1-one: a differentiation inducing factor isolated from dictyostelium discoideum
1-(3-chloro-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone: ; endogenous differentiation-inducing factor; induces stalk-cell differentiation in the cellular slime mold dictyostelium discoideum
1-(3-chloro-4-fluorophenyl)-3-(3,4-dichlorophenyl)urea: has antimalarial activity
1-(3-chloro-4-hydroxyphenyl)-5-methoxy-3-(N-methylcarbamoyl)pyrazole: pz 177 metabolite
1-(3-chloro-5-((4-(4-fluoro-3-(trifluoromethyl)phenyl)thiazol-2-yl)carbamoyl)pyridine-2-yl)piperidine-4-carboxylic acid: nonpeptidyl thrombopoietin receptor agonist
1-(3-chloromethylene-2,3-dihydro-1-benzoxepin-7-yl)ethanone: a naturally occuring pterulone
1-(3-chlorophenethyl)-3-cyclopentylpyrimidine-2,4,6-(1H,3H,5H)-trione: a ca(v)1.3 channel antagonist; structure in fisrt source
1-(3-chlorophenyl)-1-methyl-2-phenyl-2-(2-pyridine)ethanol: rn given refers to cpd without isomeric designation
1-(3-chlorophenyl)-2-(4-hydroxyphenyl)-1-methyl-2- (2-pyridine)ethanol: rn given refers to cpd with unspecified isomeric designation
1-(3-chlorophenyl)-4-(1-(4-cyanobenzyl)imidazolylmethyl)-2-piperazinone: a farnesyl transferase inhibitor
1-(3-chlorophenyl)-5-methoxy-3-(N-methylcarbamoyl)pyrazole: pz 177 metabolite
1-(3-chlorophenyl)biguanide: rn given refers to parent cp; a 5-ht3 receptor agonist
1-(3-chlorophenyl)piperazine: supposed metabolite of trazodone; rn given refers to parent cpd
1-(3-cyano-4-(1H-pyrazol-4-yl)phenyl)-3-(5-(pyridin-4-yl)-1,3,4-thiadiazol-2-yl)urea: inhibits bloom helicase
1-(3-cyanobenzylpiperidin-4-yl)-5-methyl-4-phenyl-1,3-dihydroimidazol-2-one: dopamine d4 receptor antagonist
1-(3-dimethylaminopropyl)-1-(4-fluorophenyl)-3-oxo-1,3-dihydroisobenzofuran-5-carbonitrile: inhibits pla2 and hemorrhagic activities of viper venoms
1-(3-fluoro-2-pyridinyl)piperazine: rn & ; rn given refers to parent cpd
1-(3-fluoro-4-(trifluoromethyl)phenyl)-N-(1,1,1-trifluoropropan-2-yl)-3,4-dihydroisoquinoline-2(1H)-carboxamide: an inhibitor of trpm8
1-(3-fluorobenzyl)-4-(3-((2-(5-methoxy-1H-indol-3-yl)ethyl)amino)-3-oxoprop-1-en-1-yl)pyridin-1-ium: a cholinesterase inhibitor with both antioxidant and neuroprotective activities
1-(3-fluoropropyl)-2-nitroimidazole: lipophilic compound used for imaging hypoxia
1-(3-fluoropropyl)-4-(4-cyanophenoxymethyl)piperidine: selective sigma-1 receptor ligand
1-(3-hydroxy-4-(hydroxymethyl)-cyclopentyl)-5-(2-bromovinyl)-2,4-(1H,3H)-pyrimidinedione: rn & ; rn refers to (e)-isomer
1-(3-hydroxy-4-(hydroxymethyl)cyclopentyl)-5-(2-iodovinyl)-2,4-(1H,3H)-pyrimidinedione: rn & ; rn refers to (e)-isomer
1-(3-hydroxy-4-methoxy-5-methylphenyl) ethanone: a compound from the stem bark of lamprothamnus zanguebaricus
1-(3-hydroxy-6-(hydroxymethyl)-4-oxopyridyl)-2-ethanesulfonic acid: increases iron excretion into bile & urine of rats when given parenterally
1-(3-hydroxy-7-acetylnaphthalen-2-yl)ethanone: from the rhizome of cynanchum otophyllum schneid (asclepiadaceae)
1-(3-hydroxyandrostan-17-yl)-2-propen-1-one: vinyl ketone with active-site directed inactivation of rat 20alpha-hydroxysteroid dehydrogenase
1-(3-hydroxypentyl)-3-(1-naphthoyl)indole: a metabolite of jwh-018
1-(3-hydroxyphenyl)-2-(4-aminobenzoyl)-6-chloro-1,2,3,4-tetrahydro-beta-carboline: inhibits kinesin spindle protein
1-(3-hydroxyphenyl)-2-(beta-aminopropionyl)-8-chloro-1,2,3,4-tetrahydro-beta-carboline: inhibits kinesin spindle protein
1-(3-indolyl)-2-(methylamino)ethanol: rn given refers to cpd with unspecified isomeric designation
1-(3-iodophenyl)-4-(3-nitrophenyl)-1,2,3-triazole: also known as pmi - p62-mediated mitophagy inducer
1-(3-iodopropen-2-yl)-4-((4-cyanophenoxy)methyl)piperidine: uses for visualizing sigma-1 receptors
1-(3-methoxy-4-methylphenyl)-2-aminopropane: ; rn given refers to (r,s)-isomer
1-(3-methylbut-2-enyloxy)-3-methyl-9H-carbazole: derivative of murrayafoline a
1-(3-nitrophenyl)ethyl tosylate: strucure in first source
1-(3-phenyl-2-propenyl)-1H-imidazole: potent thromboxane synthetase inhibitor
1-(3-phenylpropyl)-4-hydroxyiminomethylpyridinium: a cholinesterase reactivator
1-(3-phenylpropyl)piperidine: has antidepressant activity
1-(3-picolinium)-12-triethylammonium-dodecane dibromide: nicotinic receptor antagonist for the treatment of nicotine addiction
1-(3-pyridyl)ethanol: rn given refers to cpd without isomeric designation
1-(3-pyridyl-N-oxide)ethanol: metabolite of 3-acetylpyridine
1-(3-tert-butyl-1-phenyl-1H-pyrazol-5-yl)-3-(2-(methylthio)-4-(3-oxo-3,4-dihydropyrido(2,3-b)pyrazin-8-yloxy)phenyl)urea: a raf inhibitor with antineoplastic activity
1-(3-tert-butyl-1-phenyl-1H-pyrazol-5-yl)-3-(2-fluoro-4-(3-oxo-3,4-dihydropyrido(3,2-b)pyrazin-8-yloxy)phenyl)urea: a raf inhibitor with antineoplastic activity
1-(3-thienyl)(1-(4-fluorophenyl)-4a-methyl-4,4a,5,6,7,8-hexahydro-1H-benzo(f)indazol-5-yl)methanone: a glucocorticoid receptor ligand with nsaid activity
1-(3-trifluoromethylphenyl)-3-((5-isoquinolinyl)carbonyl)-5-methylpyrazole: a neuropeptide y5 receptor antagonist
1-(3-trifluoromethylphenyl)piperazine: acts as serotonin agonist
1-(4'-acetamidophenylazo)-2-naphthol: naphthol analog of disperse yellow 3
1-(4'-bromo-4-biphenylyl)-1-(4-chlorophenyl)-3-dimethylaminoprop-1-ene: rn given refers to (e)-isomer
1-(4'-bromophenyl)-6,7-dimethoxy-2-(piperidin-1-ylacetyl)-1,2,3,4-tetrahydroisoquinoline: an anticonvulsant
1-(4'-hydroxy-3',5'-dimethoxy-phenyl)-1,8-dimethoxynaphthalen-2(1H)-one: from an endolichenic fungal strain scopulariopsis sp.
1-(4'-hydroxybenzyl)-imbricatin: from pholidota yunnanensis; has inhibitory activity on nitric oxide production
1-(4'-hydroxyphenyl)-1-(aminomethyl)ethene: structure in first soosurce
1-(4'-hydroxyphenyl)-3-hydroxy-5-phenyl-1,5-pentandione: from daphne giraldii callus cells
1-(4'-thio-beta-ribofuranosyl)thymine: used in synthesizing nuclease resistant oligodeoxynucleotides
1-(4(5)-(hydroxymethyl)-1H-imidazole-2-yl)ethanone: a lymphopenic metabolite of 2-acetyl-4-(tetrahydroxybutyl)imidazole (thi), a component of caramel color iii
1-(4,4-bis(4-fluorophenyl)butyl)-4-(2-hydroxy-3-(phenylamino)propyl)piperazine: a potent dopamine uptake inhibitor
1-(4,5-dichloro-9,10-dihydro-9,10-ethanoanthracen-11-yl)-N-methylmethanamine: synthetic antidepressant
1-(4,5-dihydro-1H-imidazol-2-yl)isoquinoline: an imidazoline(1)-receptor ligand with putative antagonist activity
1-(4,5-dihydroxy-3-hydroxymethylcyclopenten-2-enyl)-1H-1,2,3-triazole-4-carboxylic acid amide: a carbocyclic nucleoside with antiviral activity against sars virus and orthopoxviruses
1-(4,6-dimethoxy-1,3,5-triazin-2-yl)pyrrolidin-3-amine: a chiral derivatizing agent for detection of chiral carboxylic acids
1-(4,6-dimethoxypyrimidin-2-yl)-3-(2-ethoxyphenoxysulfonyl)urea: herbicide
1-(4- fluorophenyl)-2-(5-(2-hydroxy-5-methoxybenzoyl)pyrimidin-2-yl)guanidine: a toll-like receptor 4 antagonist
1-(4-(((3,5-dimethylanilino)carbonyl)methyl)phenoxy)-2-methylcyclopentanecarboxylic acid: an allosteric effector of hemoglobin
1-(4-((1H-pyrazolo(3,4-d)pyrimidin-4-yl)oxy)-2-fluorophenyl)-3-(4-chloro-3-(trifluoromethyl)phenyl)urea: inhibits vegfr-1, vegfr-2, vegfr-3, fgfr2, and src kinase; has antineoplastic activity
1-(4-((2-(2-aminopyrimidin-5-yl)-7-methyl-4-morpholinothieno(3,2-d)pyrimidin-6-yl)methyl)piperazin-1-yl)-2-hydroxypropan-1-one: also inhibits mtor
1-(4-((2-hydroxy-1-phenylethyl)amino)-5,6,7,8-tetrahydropyrido(4',3'-4,5)thieno(2,3-d)pyrimidin-7-yl)-2-propen-1-one: has antineoplastic activity
1-(4-((3-(4-methylpiperazin-1-yl)propyl)amino)benzyl)-5-(trifluoromethyl)pyridin-2(1H)-one: has antifibrotic activity
1-(4-((4-diethylamino-2-hydroxybenzylidene)amino)phenyl)ethanone: a cholinesterase inhibitor
1-(4-(1,1-dimethylheptyl)-2,6-dimethoxyphenyl)-3-methylcyclohexanol: a cb2 receptor ligand
1-(4-(1,2,3,4-tetrahydroxybutyl)-1H-imidazol-2-yl)ethanone oxime: inhibits sphingosine-1-phosphate lyase
1-(4-(1-aminohydroxyiminomethyl)pyridinium)-4-(4-hydroxyiminomethylpyridinium)-but-2-ene: nerve agent antidote
1-(4-(1H-1,2,4-triazol-1-yl)benzylidene)-2-(4-(4-nitrophenyl)thiazol-2-yl)hydrazine: has antimycobacterial activity
1-(4-(1H-pyrazolo(3,4-d)pyrimidin-4-yloxy)-3-fluorophenyl)-3-(5-tert-butylisoxazol-3-yl)urea: an flt3 and wnt-beta catenin signaling inhibitor
1-(4-(2,4-difluorophenyl)piperazin-1-yl)-2-((4-fluorobenzyl)oxy)ethanone: an mglu5 positive modulator
1-(4-(2-((6-(4-(2-(dimethylamino)ethoxy)phenyl)furo(2,3-d)pyrimidin-4-yl)amino)ethyl)phenyl)-3-phenylurea: an aurora kinase inhibitor
1-(4-(2-chloro-4-fluorophenyl)piperazin-1-yl)-2-(pyridin-4-ylmethoxy)ethanone: an mglur5 agonist
1-(4-(2-ethoxy-4-methyl-1H-pyrrol-1-yl)-3-hydroxy-2,2-dimethylchroman-6-yl)-3-phenylurea: has antineoplastic activity
1-(4-(2-fluoroethoxy)benzyl)-4-phenylpiperidine-4-carbonitrile: a sigma1 receptor ligand
1-(4-(2-hydroxyethyl)piperazin-1-yl)-3,3-diphenylpropan-1-one: has anticonvulsant activity
1-(4-(2-methoxyethyl)phenoxy)-3-(((2-2-methoxyphenoxy)ethyl)amino)-2-propanol: an alpha- and beta-receptor blocking agent
1-(4-(2-methyl-4-chinolin-2-yl-piperazin-1-yl)-butyl)-8-azaspiro (4.5)decano-7,9-dione: a piperazine derivative; 5-ht agonist
1-(4-(3,4-dihydroisoquinolin-2(1H)-yl)butyl)-1,3-dihydro-2H-indol-2-one: a serotonin 5-ht7 receptor agonist
1-(4-(3,5-difluorophenyl)butyl)iminofuranose: inhibits both isomaltase and sucrase
1-(4-(3-((2-ethoxy-1,3-benzoxazol-6-yl)oxy)propoxy)phenyl)ethanone: antiviral against group a and b human rhinoviruses
1-(4-(3-(4-(1H-benzo(d)imidazole-2-carbonyl)phenoxy)pyrazin-2-yl)piperidin-1-yl)-2-fluoropropan-1-one: a pde10a antagonist
1-(4-(3-(4-(1H-benzo(d)imidazole-2-carbonyl)phenoxy)pyrazin-2-yl)piperidin-1-yl)ethanone: an inhibitor of phosphodiesterase 10a