NLK-NML/MeSH-CZ-2025-notes huggingface dataset:
mexacarbate: insecticide & acaricide; minor descriptor (75-82); online & index medicus search insecticides, carbamate (75-82)
mexicanin: trypanocidal sesquiterpene lactone from aerial parts of gaillardia megapotamica
mexicanolide: from the seeds of a godavari mangrove, xylocarpus moluccensis; exhibits marked antifeedant activity against the third-instar larvae of brontispa longissima (gestro)
mexiletine carbonyloxy glucuronide: a mexiletine urinary metabolite
mezerein: toxic component of plant daphne mezereum with anti-leukemic activity against p-388 & p-1210 in mice; can act as a tumor promoter; rn given refers to (12beta(e,e))-isomer
mezilamine: rn given refers to parent cpd; synonym o 6553 refers to hcl
mf2 protein, Streptococcus pyogenes: dnase from streptococcus pyogenes; amino acid
mf3 protein, S pyogenes: dnase from streptococcus pyogenes; amino acid
mgcRacGAP: specifically activates gtpases of rac and cdc42 gtp-binding proteins
mh protein, Drosophila: spartan ortholog maternal haploid is required for paternal chromosome integrity in the zygote
mhc1b.L protein, Xenopus: refseq nm_001135072
miPEP165a peptide, Arabidopsis: an 18 amino acid peptide encoded by the primary transcript of arabidopsis mir165a
miR-CT3 microRNA, human: no refseq available, sept 2022
mib1 protein, zebrafish: a ubiquitin ligase that is essential for efficient activation of notch signaling by delta; genbank af537301; refseq nm_173286
micacocidin A: a metal-containing heterocyclic antibiotic from pseudomonas sp
micacocidin B: a metal-containing heterocyclic antibiotic from pseudomonas sp
micacocidin C: a metal-containing heterocyclic antibiotic from pseudomonas sp
micellapist: a food supplement from shiitake mushroom (lentinula edodes) with anti tumor activity
michefucscalide: ; rn given refers to (3ar-(3aalpha,4alpha,6aalpha,9alpha,9aalpha,9bbeta))-isomer
michellamine A: atropisomeric naphthylisoquinoline anti-hiv cytopathic alkaloid dimers; from tropical plant ancistrocladus abbreviatus
michellamine D: a dimeric naphthylisoquinoline alkaloid from ancistrocladus korupensis
michellamine E: a dimeric naphthylisoquinoline alkaloids from ancistrocladus korupensis
michellamine F: a dimeric naphthylisoquinoline alkaloid from ancistrocladus korupensis
mico-artemin: ethereal oil extracted from wormwood (artemisia annua l.); has antimycotic activity; used for local treatment of epidermophytosis interdigitalis pedum
miconidin: found in primula; a precursor to primin; inhibits growth in trypanosoma cruzi
micp75TNFR protein, mouse: a tnf receptor type 2 (tnfr2) isoform in the mouse, termed micp75tnfr, is generated by the use of an alternative transcriptional start site within the mouse tnfr2 gene and expressed in different macrophage-like and endothelial tumor cell lines
micrandilactone B: nortriterpenoid with anti-hiv activity from schisandra micrantha
micrandilactone C: nortriterpenoid with anti-hiv activity from schisandra micrantha
microRNA miR-275, Aedes aegypti: indispensable for blood digestion and egg development in the mosquito aedes aegypti
microRNA-UL112, human cytomegalovirus: circulating mir detected in patients with glioblastoma, rheumatoid arthritis, diabetes mellitus and healthy controls
microbacterin A: from the deep sea actinomycete microbacterium sediminis sp. nov. ylb-01(t)
microbacterin B: from the deep sea actinomycete microbacterium sediminis sp. nov. ylb-01(t)
microban: contains 0.21% o-phenylphenol, 0.69% di-isobutylphenoxyethoxy-ethyldimethylbenzyl-ammonium chloride, and 0.04% bromine
microbial alkaline proteinase inhibitor: specific inhibitor for serine and thiol proteinases; do not use /antag; structurally similar to mer-n5075a
microcin: low mw peptide antibiotics from e. coli & enterobacteriaceae; e492 isolated from klebsiella pneumoniae; rn given refers to microcin a with unknown mf; amino acid sequence has been determined
microcin B17 synthase: consists of mcbb, mcbc, and mcbd proteins; catalyzes conversion of microcin b17 precursor to microcin b17; amino acid sequence has been determined
microcin H47: is a gene-encoded peptide antibiotic produced by a natural escherichia coli strain isolated in uruguay
microcin SF608: choi = 2-carboxy-6-hydroxyoctahydroindole; hpla = alpha-hydroxy acid p-hydroxyphenyllactic acid; agma = agmatine, the decarboxylated arginine; from nontoxic strain of cyanobacterium, microcystis aeruginosa
microcionamide A: from the philippine sponge clathria (thalysias) abietina
microcionamide B: from the philippine sponge clathria (thalysias) abietina
microcionamide C: from the marine sponge clathria basilana, induces apoptosis
microcionamide D: from the marine sponge clathria basilana, induce apoptosis
microcionin-1: from marine sponge, fasciospongia sp. collected along the atlantic portuguese coast
microclavatin: cytotoxic diterpenoid from the soft coral sinularia microclavata
microcolin A: ; isolated from the blue-green alga lyngbya majuscula
microcolin B: ; isolated from the blue-green alga lyngbya majuscula
microcystin: microcystins have the general structure cyclo(d-ala-l-x-d-erythro--methylisoasp-l-y-adda-d-isoglu-n-methyldehydroala) where x and y are variable l-amino acids;
microcystin YM: from cyanobacterium microcystis aeruginosa
microcystin synthetase A: from microcystis sp.; genbank af139292 to af139348
microcystin-HtyR, Asp(3)-Dhb(7)-: isolated from oscillatoria agardhii
microcystin-LR, Asp(3)-Dhb(7)-: isolated from oscillatoria agardhii
microcystin-LR, S-hydroxypropyl-Cys(7)-: internal standard for polar and non-polar variants
microdiscusol A: polyhydroxylated steroid conjugated with taurine
microfibrillar protein: component of elastic tissue; refseq nm_005926 (mfap1), nm_002403 (mfap2), nm_008546 (mouse); genbank m59851 and s68064 (bos taurus)
microfibrillar wool keratin, type I: mw 47.6kda; amino acid sequence given in first source
microfilarial protease, Brugia malayi: a vaccine candidate for lymphatic filariasis; mw 38 kda
microfilarial sheath protein, Helminth: do not confuse with sh protein-tyrosine phosphatase, also called shp2; rn refers to l. carinii; amino acid ; isolated from brugia malayi, brugia pahangi and litomosoides sigmodontis; genbank z35444, z35445 and z35443 respectively
microgrewiapine A: from microcos paniculata with cytotoxic and nicotinic receptor antagonistic activities
microgrewiapine B: from microcos paniculata with cytotoxic and nicotinic receptor antagonistic activities
microgrewiapine C: from microcos paniculata with cytotoxic and nicotinic receptor antagonistic activities
microhelenins: from helenium microcephalum; rn given refers to microhelenin a in chemline; rn given refers to (3ar-(3aalpha,4aalpha,7alpha,7aalpha,8alpha,9aalpha))-isomer
microlenin: from helenium microcephalum; rn given refers to (3'ar-(3'aalpha,4'abeta,5'alpha(3as*,4s*,4ar*,7ar*,8r*,9ar*),7'beta,7'aalpha,8'alpha,9'aalpha))-isomer
microlobin: has both antineoplastic and anti-angiogenic activity; isolated from ferula szowitsiana
micromelone A: noncontiguous polypropionate from marine gastropod micromelo undata
micromelone B: noncontiguous polypropionate from marine gastropod micromelo undata
micromide: cytotoxin from a species of marine cyanobacterium belonging to the genus symploca that was collected in guam
micromolide: anti-tuberculosis natural product from the stem bark of micromelum hirsutum (rutaceae)
micromonospora glucosyl transferase inhibitor: mr 5700; inhibitor of streptococcus mutans glucosyltransferase, beta-glucosidase, beta-amylase and beta-glucuronidase
microneme antigen 38-kDa, Neospora: 38 kda microneme antigen in neospora caninum; amino acid
microneme protein 5, Eimeria tenella: a micronemal glycoprotein; amino acid ; genbank aj245536
microneme protein 8, Toxoplasma gondii: an essential invasion factor; amino acid
micronomicin: de 020 & de 020 eyedrops both consist of kw 1062, benzalkonium chloride, sodium chloride, sodium hydroxide & distilled water ph 7.4; rn given refers to parent cpd; see also record for gentamicin c
microorganism fermentation extract: derived from rice bran, papaya & seaweed extract using effective microorganisms such as photosynthetic bacteria & yeast; has antioxidant & antineoplastic activities
micropeptin 88-N: chymotrypsin inhibitor; 3-amino-6-hydroxy-2-piperidone (ahp)-containing cyclic depsipeptide from microcystis aeruginosa nies-88
micropeptin 88-Y: chymotrypsin inhibitor; 3-amino-6-hydroxy-2-piperidone (ahp)-containing cyclic depsipeptide from microcystis aeruginosa nies-88
micropeptin EI964: from cyanobacterium microcystis aeruginosa
micropeptin EI992: from cyanobacterium microcystis aeruginosa
micropeptin HH960: from microcystis aeruginosa bloom material collected at a water reservoir near kibbutz hafetz haim, israel
micropeptin HH978: from microcystis aeruginosa bloom material collected at a water reservoir near kibbutz hafetz haim, israel
micropeptin HH992: from microcystis aeruginosa bloom material collected at a water reservoir near kibbutz hafetz haim, israel
microperoxidase: hemepeptide tracer; octapeptide containing residue 14-21 from cytochrome c; has been sequenced
microphybenzimidazole: antiproliferative and antioxidant from thymelaea microphylla coss. et dur
microphyllandiolide: isolated from the aerial parts of salvia microphylla kunth
microplasmin: consists or two polypeptide chains connected by disulfide bonds; one chain is the b chain of plasmin consisting of 230 amino acids, the other peptide is the cooh-terminal portion of the a chain of plasmin consisting of 31 amino acid residues; mw 28.635kda
microplasminogen protein, human: a truncated version of the naturally occuring protein(s), bereft of the five kringles and n-terminal segment, devoid of free sulfhydry groups, and consisting essentially only of the proenzyme domain; amino acid
microsomal ethanol-oxidizing system: probably due to cytochrome p-450 2e1, 2b and 4b isomers; acts on various aliphatic alcohols; formerly indexed as ec 1.1.1.2
microsomal glutathione S-transferase-I: catalyzes the conjugation of the tripeptide glutathione to a variety of electrophilic compounds and is part of the phase ii hepatic detoxification system; amino acid ; genbank ab000884 (pig), w85543 (mouse) and af111426 (drosophila)
microsomal triglyceride transfer protein: consists of 97-kda catalytic subunit associated with protein-disulfide isomerase; transfers triglycerides between lipid membranes; amino acid ; do not confuse with mtp protein, lipid transfer protein, or ltp-i protein
microsphaerol: antibacterial from the endophytic fungi, microsphaeropsis sp. and seimatosporium sp.
microsphaerone A: a metabolite from the culture of fungus of the genus microsphaeropsis, isolated from the mediterranean sponge aplysina aerophoba
microsphaerone B: a metabolite from the culture of fungus of the genus microsphaeropsis, isolated from the mediterranean sponge aplysina aerophoba
microspinosamide: cyclodepsipeptide from the marine sponge, sidonops microspinosa
microtububle assembly protein 49, Nicotiana tabacum: immunologically cross-reactive to 51-kda sea urchin protein, involved in microtubule organizing centers in plants;
microtubule corset protein, Crithidia: mw 33,000, dimer of 66,000; from corset microtubules of crithidia fasciculata
microtubule cross-linking protein, Artemia: mw 49 kda; has low level of nucleotidase activity, preferring either atp or gtp as substrate; located in cytoplasm; amino acid sequence has been determined
microtubule nexin: identified in electron micrographs of axonemes as a flexible protein that connects neighboring doublet microtubules
microtubule-associated protein 1B: an abundant developmentally regulated neuronal protein that is a stoichiometric complex of a heavy chain and 2 light chains, encoded as a polyprotein; essential for neuronal differentiation; mw 340 kda; amino acid sequence has been determined
microtubule-associated protein 9, zebrafish: refseq nm_001278845
microtubule-associated protein HMW4: different from well-characterized brain microtubule proteins; from mammalian nerve; shows atp-sensitive binding to microtubules & atpase activity
microtubule-associated protein-2 phosphatase: does not fit into any of the classes of protein phosphatases (types 1,2a,2b & 2c) involved in cellular regulation
microtubule-organizing center-associated polypeptide, insect: from the spindle of pales spermatocyes; particularly abundant in the centrosomes of dividing cells; mw 112 kda and pi of 5.6, from nematocera (pales ferruginea)
microvillin: 200kd nonglycosylated, nonphosphorylated protein which can be localized in microvilli
microviridin J: metabolite of microcystis that causes a lethal molting disruption in daphnia sp., upon ingestion of living cyanobacterial cells; consists of an acetylated chain of 13 amino acids arranged in three rings and two side chains
microvirin protein, Microcystis aeruginosa: an hiv entry inhibitor
microxine: a cdc2 kinase inhibitor from the australian marine sponge microxina species
mid protein, Drosophila: negative regulator of wingless transcription; amino acid ; refseq nm_135083
mid-regional pro-adrenomedullin, human: fragment of proadrenomedullin
midaglizole: orally effective hypoglycemic agent structurally unrelated to known hypoglycemics; rn given for parent cpd
midcarboxylterminal parathyroid hormone: used in assay of circulating human parathyroid hormone; may cover hpth(44-68) or hpth(39-68)
midecamycin: minor descriptor (75-80); on-line search leucomycins (75-80); index medicus search antibiotics (75-80); macrolide antibiotic
midecamycin 4''-acylase: use two apostrophes to type ''; when expressed in spiramycin producing strains of s. lividans, forms propionylspiramycin ii and iii
midecamycin 4''-propionyltransferase: use two aposptrophes to type ''
midgut lectin, Glossina: a blood-meal-induced midgut lectin from tsetse fly, glossina sp.; mw about 61 kda
midkine receptors: is a heparin-binding growth factor with migration-promoting and survival promoting activities
midnolin: midnolin - midbrain nucleolar protein; express in developing midbrain; isolated from mouse; amino acid ; genbank ab036882
midregional pro-atrial natriuretic peptide, human: a prognostic marker in the acute phase of stroke
mifamurtide: protects mice against herpes simplex virus type 2; ; rn refers to l-alaninamide,(r)-isomer; a macrophage activator; called muramyl tripeptide but that term is ambiguous, confused with other tripeptides of muramic acid
migarin: composed of methyl cellulose, phosphate buffer, propylene glycol, and benzalkonium bromide; a gel applied to nasal mucous membranes to protect against noxious industrial dusts
mighty protein, mouse: a promyogenic factor involved in skeletal myogenesis; genbank bc003291
miglyol 812: mixture of triglycerides with 50-64% c6 & 30-45% c10 fatty acids
miglyol 840: a propylene glycol diester of saturated vegetable fatty acids (c8-c10 chain lengths)
migmatoxin: suggested nomenclature for toxin identified with toxic shock syndrome from staph aureus; has properties similar to pyrogenic exotoxins & enterotoxins (migma is greek for mixture or blend)
migracin A: from the culture broth of streptomyces sp. mi264-nf2.
migracin B: from the culture broth of streptomyces sp. mi264-nf2.
migraeflux-orange: combination of dimenhydrinate, paracetamol, codeine po(4)
migraleve: contains buclizine, acetaminophen, codeine & dioctylsodiumsulphosuccinate
migration inhibitory factor suppressor factor: mediates regulation of lymphokine production; inhibits macrophage migration inhibitory factors
mik1 protein, S pombe: phosphorylates p34cdc2 on tyr(15)
mikarin: a 47 kda prothrombin activator from the venom of micropechis ikaheka; amino acid
mikatoxin, Micropechis ikaheka: isolated from the venom of the new-guinean small-eyed snake micropechis ikaheka; a homogenous peptide of mw 7775 da; partial n-terminus amino acid
milameline: a candidate drug for the treatment of age-related disorders of cognition; rn refers to the e-isomer
milbemycin alpha(31): from streptomyces bingchenggensis
milbemycin oxime: used for heartworm (dirofilaria immitis) and mites in dogs
milbex: consists of 4-chlorophenyl-2,4,5-trichlorophenylazosulfide & 1,1-bis(4-chlorophenyl)ethanol; structures
miliacin: from millet; has effect on lysosomal enzyme activity; rn given refers to (3beta)-isomer
militarinone B: pyridone alkaloid from the insect pathogenic fungus paecilomyces militaris
militarinone C: pyridone alkaloid from the insect pathogenic fungus paecilomyces militaris
militarinone D: pyridone alkaloid from the insect pathogenic fungus paecilomyces militaris
milk-derived factor: a low mw (10 kda) cpd consisting primarily of carbohydrates with traces of 18-carbon fatty acids; isolated from milk of dairy cattle following hyperimmunization with multivalent vaccine; increases resistance to staphylococcus aureus
millepachine: isolated from millettia pachycarpa benth (leguminosae)
millepurpan: isolated from medicago sativa, induce apoptosis and overcome multidrug resistance in leukemia p388 cells
millericin B: catalyzes the hydrolysis of the peptide portion of cell wall peptidoglycan; genbank af243359
millesianin H: anti-inflammatory from the stems of millettia dielsiana harms
millesianin I: anti-inflammatory from the stems of millettia dielsiana harms
millettocalyxin A: from the stem bark of millettia erythrocalyx (leguminosae)
millettocalyxin B: from the stem bark of millettia erythrocalyx (leguminosae)
millettocalyxin C: from the stem bark of millettia erythrocalyx (leguminosae)
milonine: relaxes both vascular and non-vascular smooth muscle tissues; isolated from cissampelos sympodialis
milt protein, Drosophila: axonal transport of mitochondria to synapses depends on milton; 1116 amino acid residues; genbank ay038000-1
miltefosine transporter, Leishmania donovani: a p-type atpase; genbank ay321297
miltipolone: an antineoplastic agent isolated from danshen, the dried root of salvia miltiorrhiza
miltirone: from salvis miltiorrhiza bunge; central benzodiazepine receptor ligand
miltpain: from the milt of chum salmon, oncorhynchus keta; mw about 22 kda; n-terminal amino acid sequence given in first source
mim-1 protein, Gallus gallus: an endogenous substrate protein for arginine-specific adp-ribosyltransferase in chicken polymorphonuclear leukocytes; genbank m29448
mimosifolenone: isolated from the rootwood of aeschynomene mimosifolia
mimosifoliol: isolated from the rootwood of aeschynomene mimosifolia
minactivin: secreted by monocytes; mw 66,000; inactivates the human urokinase-type plasminogen activators having mw 52,000 & 36,000; no other info available 12/83
minaprine: agr 1240 refers to di-hcl; short-acting type a mao inhibitor (maoi) of mild potency
minax toxin: mw 7000 basic polypeptide with 66 amino acids from scorpion buthus minax
minax toxin 2: mw 6800 basic polypeptide with 62 amino acids from scorpion buthus minax
mineral acids, trace elements, water, drug combination: a trace element preparation containing zinc that elevates the number of glucocorticoid receptors in peripheral lymphocytes isolated both from healthy blood donors and rheumatoid arthritis patients
mineral trioxide aggregate: contains tricalcium silicate, tricalcium aluminate, tricalcium oxide, silicate oxide, and a few other mineral oxides; powder consists of fine hydrophilic particles which set in the presence of moisture
miniagrin protein, mouse: a miniature version of agrin, can functionally compensates for laminin-alpha2 deficiency in the murine models of congenital muscular dystrophy; genbank ay914875
minichromosome maintenance protein 5, zebrafish: depletion of mcm5 in the zebrafish retina causes cell-cycle defect and apoptosis
minigastrin, des-Trp(1)-Nle(12)-: amino acid sequence given in first source; minigastrin ii is the hydrogen sulfate ester of minigastrin i
minimiflorin: from the roots of the tropical tree lonchocarpus oaxacensis
miniolutelide A: hybrid polyketide-terpenoid metabolite from penicillium minioluteum
miniolutelide B: hybrid polyketide-terpenoid metabolite from penicillium minioluteum
miniplacental alkaline phosphatase: engineered human placental alkaline phosphatase; miniplap 208 has the same n- and c-terminal signal peptides as placental alkaline phosphatase
miniplasmin: consists of the cooh-terminal 119-residue fragment of plasmin heavy chain (residues 442-560) connected by 2 disulfide bridges (cys-557 to cys-565 & cys-547 to cys-665) to the light chain of normal plasmin (residues 561-790)
miniplasminogen: mw 39,000; kringle 5 of plasmin a chain & intact plasmin b chain
miniprion protein PrP106, mouse: a synthetic protein consisting of prp with delta(23-88) and delta(141-176) deletions
miniproinsulin: proinsulin homologue in which the length of the connecting c-peptide is reduced to a dipeptide
minor H antigen H60: mouse minor h antigen; amino acid ; genbank af084643
minor histocompatibility antigen H47: encoded by the polymorphic h4 locus defining the cd8 t cell epitope for graft rejection in mice; genbank af335543
minovincinine-19-hydroxy-o-acetyltransferase, periwinkle: acetyl coenzyme a-dependent o-acetyltransferase in madagascar periwinkle (catharanthus roseus g. don), involved in the terminal steps in the biosynthesis of the monoterpenoid indole alkaloids vindoline and minovincinine; amino acid
minovine: alkaloid of the aspidosperma & iboga families; structure vinca minor alkaloid
minquartynoic acid: isolated from minquartia guianensis & ochanostachys amentacea; a tetra-alkyne
minutoside A: antifungal sulfated steroid xyloside from the patagonian starfish anasterias minuta
minutoside B: antifungal sulfated steroid xyloside from the patagonian starfish anasterias minuta
mio protein, Drosophila: encodes a highly conserved nuclear protein required for the maintenance of the meiotic cycle and oocyte identity in drosophila
mipA protein, Emericella nidulans: cotains 454 amino acid residues
mipomersen: an antisense oligonucleotide that binds apolipoprotein b mrna and inhibits expression of apob
mir-iab8-3p, Drosophila: refseq nr_048417.1 (mir-iab8-3p)
mirabalin: originally from the marine sponge siliquariaspongia mirabilis
mirabilicin D-52: bacteriocin produced by proteus mirabilis d-52
mirabilin: isolated from tubers of cyclamen mirabile; mirabilin g (an alkaloid) is also available
mirabilin (macrolide lactam): an antitumor macrolide lactam from the marine sponge siliquariaspongia mirabilis
mirabilin G: guanidine-containing alkaloid (related to the ptilocaulins) from southern australian marine sponge, clathria species; mirabilin (a triterpene) is also available
miraculin protein, Synsepalum dulcificum: taste affecting glycoprotein isolated from miracle fruit, synsepalum dulcificum, which provokes sweetness & blocks sourness
miramides: three amino acid residue depsipeptides with a short fatty acid chain isolated from streptomyces mirabilis lu17588
mirasorvone: a masked 20-ketopregnane from the defensive secretion of diving beetle, thermonectus marmoratus
miravirsen: has antiviral activity; a 15-nucleotide locked nucleic acid-modified antisense oligonucleotide that inhibits mir-122
mirdametinib: has antineoplastic activity; appears to be a mek inhibitor
mirestrol: plant extract used as rejuvenating drug in se asia potent estrogenic activity
miridesap: small molecule compound that depletes serum amyloid p component (sap)
mirikizumab: a humanized immunoglobulin g4-variant monoclonal antibody that binds to the p19 subunit of il23 and does ,treatment of patients with moderately to severely active uc
mirisetron: rn refers to endo, (z)-2-butenedioate (1:1)
mirn15 microRNA, rat: modulates expression of the cell-cycle regulator cdc25a and affects hepatic cystogenesis in a rat model of polycystic kidney disease
mirn181 microRNA, mouse: involved in t and b cell development; has been sequenced
mirn199 microRNA, human: regulates expression of ikkbeta; has been sequenced
mirn206 microRNA, rat: may have a role in the pathophysiology of muscular dystrophy; refseq nr_031921.1
mirnlet7 microRNA, mouse: refseq nr_029727 (let-7a)
mirnlet7 microRNA, zebrafish: refseq nr_029979 (let7a-4)
mirr protein, Drosophila: a pbx class protein that functions in the definition of the dorsal-ventral border in the eye; homologous to caupolican protein; amino acid sequence given in first source; genbank u95021
mirvetuximab soravtansine: an antineoplastic conjugate of m9346a monoclonal antibody and n2'-deacetyl-n2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine that targets folate receptor-alpha
mis12 protein, S pombe: required for giving correct metaphase spindle length; amino acid
misakimycin: a mammalian cell growth stimulating substance produced by streptomyces misakiensis bp-3621
miserotoxin: toxin from emory milkvetch; measured by nitro moiety
misgurin: isolated from the loach misgurnus anguillicaudatus; amino acid
mismatch-specific thymine uracil-DNA glycosylase: catalyzes base-excision of a self-complementary oligonucleotide with central g/t mismatches
mistletoe lectin III: ml3 binds n-acetyl-galactosides
mitapivat: an oral, small-molecule allosteric activator of pyruvate kinase
mitiglinide: a rapid and short-acting hypoglycemic agent; acts on sulfonylurea receptor closing katp channels; considered one of the glinides-an imprecise grouping
mitilysin, Streptococcus mitis: a secreted cholesterol-dependent cytolysin (mitilysin); partial amino acid
mito-FF: self-assembly peptide that targets mitochondria, and consists of diphenylalanine, tpp, and pyrene
mito-carboxy proxyl: a mitochondrially-targeted antioxidant with antineoplastic activity
mitoNEET protein, mouse: an outer mitochondrial membrane protein with a zinc finger-like domain; genbank bc013522
mitocalcin, mouse: mitochondrial ca2+-binding protein with ef-hand and coiled-coil domains; may play roles in neuronal differentiation and function through the control of mitochondrial function
mitochondria proteolipid-like protein, human: a human carcinoma-associated tumor suppressor gene product; amino acid sequence given in first source; don't confuse with mpl protein, human
mitochondrial ATPase subunit c: major accumulating protein in several forms of ceroid lipofuscinosis, amino acid sequence found to be identical to that of the f0 subunit of mitochondrial atp synthase
mitochondrial K(ATP) channel: purified from the inner mitochondrial membrane and reconstituted into lipid bilayer membranes
mitochondrial acyl-CoA thioesterase I, mouse: silencing the expression of mitochondrial acyl-coa thioesterase i and acyl-coa synthetase 4 inhibits hormone-induced steroidogenesis
mitochondrial addressing peptide: 13 amino acid residues (mlslrqsirffky) given in first source; blocks a cationic channel from mitochondrial membrane; the first 12 aa form the n-terminal part of cytochrome c oxidase subunit iv precursor from the yeast saccharomyces cerevisiae
mitochondrial antigen 36 kDa: tryptic fragment of antigen from mitochondrial inner membrane proteins; reacts with antimitochondrial antibody in sera of patients with primary biliary cirrhosis
mitochondrial carboxypeptidase-III: metallocarboxypeptidase from rat liver mitochondria; releases c-terminal alanine twice as fast as any other amino acid
mitochondrial carrier 1 protein, Anopheles gambiae: required to maintain mitochondrial membrane potential in mosquito midgut cells and modulates epithelial responses to plasmodium infection
mitochondrial import stimulation factor, rat: consists of two components; ywhaz is a 30kda and prkcz is a 32kda component of the mitochondrial import stimulation factor, a protein complex that facilitates the import of in vitro synthesized precursor proteins into mitochondria; rn refer to subunit l
mitochondrial intermediate peptidase: removes the octapeptide from the amino terminus of the intermediate protein processed from the protein precursor of certain mitochondrial proteins by the mitochondrial processing peptidase; smip from schizophyllum commune; rmip from rat; ymip from saccharomyces cerevisiae
mitochondrial intermembrane space protease: 200-kda; adp, amp, and nonhydrolysable atp analogs can substitute for atp; isolated from rat liver and studied in humans; no sequence links or genome database entry available
mitochondrial magnesium exporter 1, S cerevisiae: refseq nm_001182670
mitochondrial malate translocator, Panicum miliaceum: isolated from leaves of proso millet, panicum miliaceum; amino acid ; genbank d45073 (pomt134), d45074 (pomt106), and d45075 (pomt103)
mitochondrial matrix protein, 67-kDa, rat: involved in regulating the initiation of leading-strand replication; has been sequenced
mitochondrial membrane protein 73: a 73 kda protein from inner mitochondrial membrane from rat hepatocytes; amino acid sequence given in first source
mitochondrial outer membrane protein 35-kDa, mouse: has high homology to tom40 of neurospora crassa & s. cerevisiae; amino acid
mitochondrial oxidative damage endonuclease: an 8-oxog-specific dna endonuclease from rat liver mitochondria; recognizes and incises at 8-oxog & abasic acid sites in duplex dna
mitochondrial phosphate transport protein, S cerevisiae: a homodimeric mitochondrial phosphate transport protein; has been sequenced
mitochondrial phosphoprotein, 65-kDa: isolated from rat liver; amino acid sequence given in first source; genbank ab000098
mitochondrial polynucleotide phosphorylase, Arabidopsis: genbank cab43865
mitochondrial protein 17 kDa, rat: a mitochondrial protein ("mitoneet") cross-linked specifically by a thiazolidinedione photoprobe; located in mitochondrial fraction of rodent brain, liver, skeletal muscle, and preadipocytes; has been sequenced
mitochondrial protein 206, Lycopersicon esculentum: isolated from tomato; amino acid ; genbank d84426; do not confuse with mitochondrial protein 206 from oenothera
mitochondrial protein 206, Oenothera villaricae: component of a heme transporter involved in cytochrome c biogenesis in oenothera; amino acid sequence given in first source; genbank x74164
mitochondrial protein mtDBP-C, Xenopus: from xenopus laevis; amino terminal amino acid sequence given in first source
mitochondrial ribosomal protein L34, Drosophila: regulates differentiation in the eye
mitochondrial ribosomal protein L44, human: mutation linked to underlie mitochondrial infantile cardiomyopathy; refseq nm_022915
mitochondrial ribosomal protein S12: has been sequenced; refseq nm_033362
mitochondrial ribosomal protein YmL20: transported into isolated mitochondria in an energy-dependent manner; amino acid sequence has been determined
mitochondrial ribosomal protein YmL27: essential for mitochondrial function in yeast; mature yml27 consists of 130 aa residues; mw 14,798 da; aa sequence has been determined
mitochondrial ribosomal protein YmL8: transported into isolated mitochondria in an energy-dependent manner; amino acid sequence has been determined
mitochondrial transcription factor A: a nuclear-encoded gene product that is imported into mitochondria and is required for the transcription of mitochondrial dna (mtdna)
mitochondrial ubiquitin ligase 1, Drosophila: refseq nm_001316436
mitochondrial uncoupling protein, chicken: involved in facultative muscle thermogenesis in birds; homologs in plants & mammals; amino acid  (chicken)
mitochondrial zinc maintenance protein 1, S cerevisiae: a cytochrome bc1 assembly factor; refseq nm_001180801
mitoferrin protein, mouse: erythroblasts generated from murine embryonic stem cells null for mfrn (also known as slc25a37) show maturation arrest with severely impaired incorporation of 55fe into haem
mitogen and stress-activated protein kinase 1: activated by map kinases, involved in activation of creb protein (dna-binding protein, cyclic amp-responsive); amino acid
mitogen-activated protein kinase kinase kinase 12: serine/threonine kinase but hybrid between microtubule- associated protein kinase kinase kinases and the fibroblast growth factor receptor family
mitogenic bacterial lipoprotein, E coli: mw 35,000; major binding protein found on mouse primary lymphocytes; has binding capacity for the biologically active n-terminal structure of the lipoprotein
mitogenic exotoxin Z protein, Streptococcus: a superantigenic toxin produced by s. pyogenes; genes spex & smez are allelic
mitogenic factor, Streptococcus: distinct from previously described streptococcal pyrogenic exotoxins; 271 aa residues, mw about 25 kda; amino acid sequence given in first source; genbank d13428
mitomalcin: isolated from streptomyces malayensis; may be similar in structure to neocarzinostatin
mitomycin A: rn given refers to (1as-(1aalpha,8beta,8aalpha,8balpha))-isomer
mitomycin C-N(2)-deoxyguanosine adduct: has antibiotic and cytotoxic effects
mitomycin C-anti-alpha-fetoprotein antibody conjugate: enhanced antitumor activity
mitomycin C-dextran: polymeric prodrug of mitomycin c-dextran conjugate
mitomycin C-immunoglobulin M antibody conjugate: antibody drug conjugate used as antitumor agent with improved tumor specificity
mitomycin D: rn given for (1as-(1aalpha,8alpha,8aalpha,8balpha))-isomer
mitotic apparatus-associated protein p62, sea urchin: putative tubulin- and chromatin-binding protein; genbank u76750
mitotic centromere-associated kinesin, Xenopus: belongs to the kinesin-13 family, whose members depolymerize microtubules rather than translocate along them
mitotic chromosome-associated protein, 200-kDa: belongs to the bet subgroup of the bromodomain superfamily; associates with mitotic chromosomes and affects g(2)-to-m transition; amino acid
mitragynine pseudoindoxyl: derived from thai medicinal plant mitragyna speciosa; opioid agonist
mitran: a mixture of chlorfenethol and ovex; merck index says ovex and mitran are the same compound
mitrocomin protein, Mitrocoma celluria: from mitrocoma cellularia; consists of 190 amino acids; has three calcium-binding sites & a tyr residue at the c-terminus; aa sequence given in first source
miyakolide: antineoplastic from marine sponge of the genus polyfibrospongia
mizoribine: imidazole nucleoside with immunosuppressive activity isolated from culture filtrate of eupenicillium brefeldianum
mj1477 protein, Euryarchaeota: functions as a cysteinyl trna synthetase in archeae such as methanoccus and methanobacterium; sequence does not fit either of the two known classes of aminoacyl trna synthetases; amino acid
mkaB protein, Salmonella typhimurium: amino acid sequence given in first source
mkaC protein, Salmonella typhimurium: amino acid sequence given in first source
ml3 lysin protein, Lactococcus phage c2: from prolate-headed lactococcal bacteriophage c2; amino acid sequence given in first source
mlaC protein, E coli: gene id: 947710; no refseq available
mlpA protein, Myxococcus xanthus: required for normal development of myxococcus xanthus; amino acid sequence has been determined; do not confuse with fungal mlpa protein
mlpA protein, Physarum polycephalum: isolated from physarum polycephalum; c-terminal amino acid ; genbank z21878
mls-1 protein, C elegans: involved in determining fate of nonstriated muscle; amino acid
mma4 protein, Mycobacterium tuberculossis: catalyzes conversion of cis-olefin to a secondary alcohol with adjacent methyl branch during biosynthesis of methoxymycolates; isolated from mycobacterium tuberculossis; amino acid ; genbank u66108
mmf1 protein, S pombe: schizosaccharomyces pombe pmf1p is structurally and functionally related to mmf1p of saccharomyces cerevisiae; amino acid
mmy protein, Drosophila: a udp-n-acetylglucosamine diphosphorylase that catalyzes the conversion of utp and n-acetylglucosamine-1-phosphate to pyrophosphate and udp-n-acetylglucosamine; involved in nervous system development
mnemiopsin: photoprotein isolated from mnemiopsis; induces bioluminescence in the presence of calcium
mngR protein, E coli: a fatty acid/fatty acyl-coa responsive protein; a probable transcription regulator of the succinyl-coa synthase operon; negatively autoregulates its own synthesis in response to long-chain fatty acid deficiency has been sequenced
mniopetal E: rn given for (3alpha,3aalpha,6aalpha,9alpha,10alpha,10as*)-isomer
mntA protein, Lactobacillus plantarum: isolated from lactobacillus plantarum; has been sequenced; genbank af136521
mobA protein, E coli: molybdopterin-guanine dinucleotide biosynthesis protein a; required for molybdenum cofactor biosynthesis; isolated from e. coli; amino acid ; do not confuse with moba protein, a mobilization protein; do not confuse with chlb protein, an algal protein; homologous moba protein found in other bacteria
mobilat: ointment consisting of 20% adrenal extract, 0.2% mucopolysaccharide polysulfuric acid ester & 2% salicylic acid; see also record for dolo mobilat
mobilferrin: a 56 kda iron-binding protein from rat enterocytes; amino acid sequence has been determined
mobilization protein MobD, bacteria: required for mobilization of non-self-transmissible plasmid pec3; isolated from many bacteria; genbank d45188
mocarhagin: cleaves 10 aa peptide from n terminus of p-selectin ligand receptor; cleaves the platelet von willebrand factor receptor glycoprotein ib alpha (gpib alpha); genbank ay101383
moctamide: synthetic amide of linoleic acid which significantly depresses serum cholesterol levels; rn given refers to (s-(z,z))-isomer
mod protein, Drosophila: binds nucleolar rna, dna, and chromatin; isolated from drosophila; amino acid ; refseq nm_079875
mod(mdg4) protein, Drosophila: binds to gypsy insulator and interacts with suppressor of hairy-wing, su(hw), to produce polar effect; doom is an alternative splice product of mod(mdg4) gene; amino acid ; refseq nm_163878
mod5 protein, S pombe: fission yeast mod5p regulates polarized growth through anchoring of tea1p at cell tips; has been sequenced
modF protein, E coli: from e. coli; may be involved in photorepair; involved in the transport of molybdenum into the cell; could also act on uv-induced dna damage other than pyrimidine dimers; amino acid sequence given in first source; genbank x69182
modeccin: from modecca digitata harv, passifloracea growing in austral africa; fruits & roots are very poisonous to man; also isolated from adenia digitata
modeccin A-chain-ricin B-chain hybrid toxin: disulfide conjugates of modeccin a-chain and ricin b-chain
modelin 1: an amphiphilic synthetic peptide; amino acid sequence given in first source
modelin 5: a synthetic amphiphilic peptide; amino acid sequence given in first source
modification methylase BseMII: part of a type iv restriction-modification system; recognizes 5'-ctcag; modifies adenine residues in both strands of target dna to form n6-methyladenine
modified Dakin's solution: made from household bleach (sodium hypochlorite), baking soda (sodium bicarbonate), and water; used in wound care for chemical debridement & the stimulation of granulation tissue
modified sini: has hepatoprotective activity; used to treat heart and liver diseases; consists aconitum carmichaelii, zingiber officinale, glycyrrhiza uralensis, panax ginseng, and prunus mume
modified sinisan: has hepatoprotective activity; bupleurum chinense, citrus aurantium, paeonia lactiflora, glycyrrhiza uralensis, astragalus membranaceus, ostrea gigas, and xiongdan
modified yi guan jian: prepared from coastal glehnia root, ophiopogonis tuber, angelica, dried rhizome of rehmannia, wolfberry fruit, fructus toosendan, and polygonum cuspidatum
modiolide A: 10-membered macrolide from a marine-derived fungus, paraphaeosphaeria sp. which was separated from a marine horse mussel
modiolide B: 10-membered macrolide from a marine-derived fungus, paraphaeosphaeria sp. which was separated from a marine horse mussel
moducrin: combination of amiloride, hydrochlorothiazide & timolol maleate
moeB protein, Bacteria: a molybdopterin biosynthesis protein; has been sequenced
moellendorffiline: isolated from root of heracleum moellendorffii; mf: c26-h20-o10
moesin: amino acid ; member of the protein 4.1-talin-ezrin family of proteins; refseq nm_002444 (human), nm_010833 (mouse), nm_030863 (rat)
moesin, Drosophila: homologous to moesin; amino acid ; genbank l38909
moexiprilat: rn given refers to (3s-(2(r*(r*)),3r*))-isomer; rn for cpd without isomeric designation not available 6/89
mof protein, Drosophila: histone acetyltransferase; required for histone acetylation involved in dosage compensation for x-linked genes in drosophila melanogaster; dosage compensation insures that males with a single x chromosome have the same amount of most x-linked gene products as females with two x chromosomes; member of the myst histone acetyltransferase family; refseq nm_078496
mofezolac: cyclooxygenase 1 inhibitor; ; rn from toxlit
mog-1 protein, C elegans: sex determination protein, encodes a member of the deah-box protein family; probable atp binding rna helicase involved in pre-mrna splicing, genbank af120269
mog-4 protein, C elegans: probable pre-mrna splicing factor atp-dependent rna helicase; encodes a deah helicase isolated from caenorhabditis elegans; orthologous to the drosophila cg10689 and the s. cerevisiae prp2 proteins; amino acid
mog-5 protein, C elegans: probable pre-mrna splicing factor atp-dependent rna helicase ; encodes a deah helicase isolated from caenorhabditis elegans; orthologous to the drosophila cg8241, the human hrh1, and the s. cerevisiae prp22 proteins
mogamulizumab: a defucosylated humanized anti-ccr4 antibody
mogoltacin: an antineoplastic agent isolated from the fruit of ferula badrakema
mogroside IIIE: a cucurbitane-type triterpenoid from siraitia grosvenorii fruit
mogroside IV: sweet triterpene glycoside from fruit of momordica grosvenori swingle
mogroside V: cucurbitane type sweet triterpene glycoside from fruit of momordica grosvenori swingle; rn given refers to (3beta,9beta,10alpha,11alpha,24r-all d)-isomer
mogroside VI: sweet triterpene glycoside from fruit of momordica grosvenori swingle
moguntinone 19: has proapoptotic, antiangiogenic, and antiproliferative activities
mohangic acid A: from a marine-mudflat-derived streptomyces sp.
mohawk protein, mouse: a member of the tale superclass of atypical homeobox proteins; genbank ak034675
moi protein, Drosophila: an hoap-interacting protein involved in telomere protection; has been sequenced; refseq nm_001144601
moiramide B: an anti-infective agent that inhibits bacterial acetyl-coa carboxylase
mojastin protein, Crotalus scutulatus: a platelet aggregation inhibitor
mokatoxin-1: a synthetic peptide based on the scorpion toxin koliotoxin-1; blocks kv1.3 channels
mol protein, Drosophila: required for recruitment of numb to the plasma membrane; amino acid ; refseq nm_135889
molassamide: a serine protease inhibitor from the marine cyanobacterium dichothrix utahensis
molecule metalloprotease-related protein-1, human: a membrane-associated protein containing a zinc metalloprotease motif; the mprp-1 gene was localized to chromosome 1-p32.3 & may have highly conserved functions, such as in intracellular proteolytic processing in the endoplasmic reticulum; genbank ab048348
molephantin: germacranolide from elephantopus mollis; rn given refers to (3ar-(3ar*,4s*,6e,9z,11s*,11as*))-isomer
molephantinin: germacranolide from elephantopus mollis; rn given refers to (3ar-(3ar*,4s*(e),6e,9z,11s*,11as*))-isomer
molgramostim: amino acid sequence given in first source; recombinant granulocyte macrophage colony-stimulating factor
molidustat: stabilizes hypoxia-inducible factor to promote erythropoietin production
mollamide B: from the indonesian tunicate didemnum molle; cytotoxic against several cancer cell lines
mollanol A: from the fruits of rhododendron molle, exhibited transcriptional activation effects on the xbp1 upstream promoter in iec-6, 293t, and raw264.7 cells
mollemycin A: an antimalarial and antibacterial glyco-hexadepsipeptide-polyketide from an australian marine-derived streptomyces sp. (cmb-m0244)
mollic acid glucoside: hypoglycemic, antidiabetic and cardiovascular agent; 1alpha-hydroxycycloartenoid saponin from combretum molle (combretaceae) leaf
mollipilin A: from cultivation of chaetomium mollipilium with nicotinamide
mollipilin B: from cultivation of chaetomium mollipilium with nicotinamide
mollisianitrile: has antifungal and antineoplastic activities; isolated from mollisa
mollislactone: sesquiterpene lactone from aristolochia mollissima hance
mollisoside A: from the new zealand and south australian sea cucumber australostichopus mollis
mollisoside B1: from the new zealand and south australian sea cucumber australostichopus mollis
mollisoside B2: from the new zealand and south australian sea cucumber australostichopus mollis
mollugogenol A: gammacerane from mollugo pentaphylla; an antifungal saponin that has spermatocidal activity; involves sperm membrane damage by increased lipid peroxidation
mollusk-derived growth factor: an aplysia protein related to insect-derived growth factor; genbank af117336 (aplysia)
molnupiravir: prodrug that's metabolized into n4-hydroxycytidine (nhc), a ribonucleoside analog
molt-inhibiting hormone: a family of crustacean neuropeptides that control molting
molt-inhibiting hormone, crayfish: isolated from the crayfish procambarus bouvieri; amino acid
molt-inhibiting hormone-like neuropeptide: from white shrimp, penaeus vannamei; homologous to nolt-inhibiting hormone; amino acid sequence given in first source
moluccensin I: from seed kernels of the cedar mangrove, xylocarpus moluccensis; displayed weak antibacterial activity against staphylococcus hominis and enterococcus faecalis
moluodan: used to treat chronic atrophic gastritis and gastric premalignant lesions; consists of bulbus lilii , rhizoma alismatis , poria, radix notoginseng, radix sanguisorbae, rhizoma ligustici chuanxiong , rhizoma acori tatarinowii , radix ophiopogonis, radix linderae, herba artemisiae scopariae, radix scrophulariae, pollen typhae, radix paeoniae alba, endothelium corneum gigeriae galli, herba dendrobii, radix angelicae sinensis, rhizoma corydalis, and rhizoma atractylodis macrocephalae
molybdenum blue: spray reagent prepared by dissolving molybdenum trioxide in h2so4 & adding powdered molybdenum; for staining phospholipids in thin layer chromatography
molybdenum telluride: used as substrate for imaging biological molecules during scanning tunnelling microscopy
molybdoarsenic acid: used in detection of phenothiazines; rn given refers to cpd with unspecified mf
molybdocene dichloride: rn & n1 from ca vol 90 form index; structure of molybdenum(1+) given in first source
molybdopterin: also see records for molybdopterin cytosine dinucleotide and molybdopterin guanine dinucleotide
molybdopterin cytosine dinucleotide: pterin of carbon monoxide dehydrogenase from pseudomonas carboxydoflava; structure has been determined
molybdopterin synthase: catalyzes the conversion of precursor z to molybdopterin by addition of dithiolene sulfur groups; refseq nm_183418 (human); escherichia coli molybdopterin synthase is a dimer of dimers containing the moad and moae proteins
mom-4 protein, C elegans: is required to downregulate pop-1, not only in e but also in other posterior daughter cells; a map kinase kinase kinase-related protein, activates wrm-1/lit-1 kinase to transduce anterior/posterior polarity signals; amino acid
momfluorothrin: a nongenotoxic synthetic pyrethroid; induced hepatocellular tumors in male and female wistar rats
momilactone A: rn given for (3ar-(3aalpha,5aalpha,8beta,10abeta,10bbeta,10calpha))-isomer
momorcharaside A: ; isolated from seeds of momordica charantia l; dna antagonist
momordicin II: has antineoplastic activity; isolated from bitter melon, momordica charantia
momordicoside M: from momordica charantia (karela/bitter gourd)
momordicoside N: from momordica charantia (karela/bitter gourd)
momordicoside O: from momordica charantia (karela/bitter gourd)
momordin I (protein): a ribosome-inactivating protein from momordica; momordin i (oleanolic acid) is also available
momordin II (protein): type 1 ribosome inactivating protein from momordica balsamina; amino acid sequence given in first source; sequence identity 51% with momordin i and 57% with trichosanthin; see also momordica charantia proteins; momordin ii (oleanolic acid) is also available
momordin-a (protein), Momordica charantia: type 1 ribosome-inactivating protein from seeds of momordica; 250 aa, mw=28,690 da; sequence identity 33% to ricin a-chain
momorgrosvin protein, Siraitia grosvenorii: a ribosome-inactivating protein from seeds of the monk's fruit momordica grosvenorii; partial amino acid
monacolin O: isolated from the ethanolic extract of monascus purpureus-fermented rice
monacolin P: isolated from the ethanolic extract of monascus purpureus-fermented rice
monacolin X: isolated from monaseus ruber; mf: c24-h34-o6
monafram: the f(ab')2 fragment of monoclonal antibody crc64; approved for clinical use in the russian federation
monalidine A: anti-parasitic (trypanosoma, leishmania) alkaloid from the marine sponge monanchora arbuscula