NLK-NML/MeSH-CZ-2025-notes huggingface dataset:
hibiscin: crystalline anthocyanin coloring material from flowers of hibiscus sabdariffa; used as dye and stain
hic2 protein, zebrafish: a btb/poz domain protein; refseq nm_182869
hieronymain I, Bromelia hieronymi: cysteine peptidase isolated from unripe fruits of bromelia hieronymi mez (bromeliaceae); the n-terminal sequence of hieronymain (alpesidwrakgavtevkrqdg) when compared with 25 plant cysteine proteases showed more than 50% of identity
hig protein, Drosophila: isolated from synaptic clefts of drosophila; amino acid ; refseq nm_165667
high affinity DNA-binding factor, S cerevisiae: from saccharomyces cerevisiae; ku is a heterodimer with mw 70 & 85 kda (hdf1 and hdf2); binds to the ends of double-stranded dna; amino acid sequence of 70 kda subunit in first source
high fluorescent intermediate II: higly fluorescent intermediate of bacterial luciferase formed by the reaction of fmnh2 & o2 with bacterial luciferase; consists of luciferase & peroxyflavin
high light-inducible protein, cyanobacteria: has similarity to the chlorophyll a/b-binding proteins of higher plants; from cynobacteria synechococcus; 72 amino acid residues; amino acid sequence has been determined
high mobility group protein D: one of the drosophila counterparts of the vertebrate hmg1/2 class of abundant chromosomal proteins; amino acid sequence given in first source
high sulfur protein B2 protein, rat: a mammalian high sulfur protein with many subtypes (b2a-f); amino acid ; genbank ab003753
high-iron diamine-thiocarbohydrazide-silver proteinate: combination of high-iron diamine, thiocarbohydrazide and silver proteinate; used in microscopy
high-molecular-weight polyprotein, feline sarcoma virus: high mw polyprotein translational product of snyder-theilen feline sarcoma virus; posseses protein kinase activity with specificity for tyrosine acceptor sites
high-potential iron-sulfur protein oxygen oxidoreductase: a member of the heme-copper oxidase superfamily; genbank aj249578
high-temperature requirement factor A1, Xenopus: the secreted serine protease xhtra1 stimulates long-range fgf signaling in the early xenopus embryo; refseq nm_001095327.1; np_001088796.1
hiiranlactone B: nsaid from the leaves of neolitsea hiiranensis
hiiranlactone D: nsaid from the leaves of neolitsea hiiranensis
hil-1 protein, C elegans: a linker histone-like nucleolar protein associated with cytoplasmic filaments in caenorhabditis elegans; has been sequenced; refseq nm_074279.5
himalensine B: from daphniphyllum himalense; showed ;inhibitory activities against two kinases, ptp1b and ikk-β
himalomycin A: has antibiotic acitivity; isolated from streptomyces
himandrine: rn given for (1r-(1alpha,4abeta,4bs*,5alpha,6alpha,7abeta,9alpha,11alpha,11aalpha,12r*,15r*))-isomer
himbacine: muscarine receptor antagonist; rn given refers to (3s-(3alpha,3aalpha,4beta(1e,2(2r*,6s*)),4abeta,8aalpha,9aalpha))-isomer
himeic acid B: a 4-pyrone ring unsaturated fatty isolated from the fungus aspergillus japonicus mf275
himeic acid C: a 4-pyrone ring unsaturated fatty isolated from the fungus aspergillus japonicus mf275
himeradine A: a c27n3-type alkaloid from lycopodium chinense
himgaline: complex polycyclic alkaloid from galbulimima belgraveana, a rain forest tree native to papua new guinea and northern australia
hinckdentine A: structurally unique marine alkaloid containing an 11b,12,13,14,15,16-hexahydroazepino[4',5':2,3] indolo[1,2-c]quinazoline ring system
hinesol: from atractylodes lance rhizome; rn given refers to (2r-(2alpha,5alpha(s*)))-isomer
hinnavin I protein, Artogeia rapae: an antibacterial peptide from cabbage butterfly, artogeia rapae; amino acid sequence given in first source
hinokinin 7-O-beta-D-glucopyranoside: isolated from the leaves of koelreuteria henryi dummer
hinokiol: has both antineoplastic and hepatoprotective activities; isolated from taiwania cryptomerioides
hinokiresinol: rn given for (s-(e))-isomer; inhibits binding of leukotriene b4 to neutrophils; structurein first source
hip1 protein, S pombe: functions in dna replication-independent nucleosome assembly; cellular response to nitrogen starvation refseq nm_001022496
hipA protein, E coli: persistence to inhibition of murein or dna biosynthesis, dna-binding regulator; probably plays a vital role in cell division; from e coli; its operon affects lethality due to inhibition of peptidoglycan or dna synthesis; amino acid sequence given in first source
hipB protein, E coli: from e coli; its operon affects lethality due to inhibition of peptidoglycan or dna synthesis; amino acid sequence given in first source
hippeastrine: isolated from amaryllidaceae; ; rn given refers to (5alpha)-isomer
hippocampal cholinergic neurostimulating peptide: amino acid sequence given in first source; involved in development of specific cholinergic neurons in central nervous system
hippocasine: azaphenalene alkaloid isolated from coccinellidae family of insects
hippolachnin A: from the south china sea sponge hippospongia lachne
hippomanin A: from phyllanthus urinaria, inhibits hsv-2 but not hsv-1 infection in vitro
hippophin K: from the seed residue of hippophae rhamnoides subsp. sinensis
hippophin L: from the seed residue of hippophae rhamnoides subsp. sinensis
hippophin M: from the seed residue of hippophae rhamnoides subsp. sinensis
hipposin protein, Hippoglossus hippoglossus: a histone-derived antimicrobial peptide in atlantic halibut (hippoglossus hippoglossus l.); mw 5458.4 da; amino acid sequence: sgrgktggkarakaktrssraglqfpvgrvhrllrkgnyahrvgagapvyl. in first source
hipposulfate A: sesterterpene sulfate from an okinawan sponge, hippospongia cf. metachromia
hipposulfate B: sesterterpene sulfate from an okinawan sponge, hippospongia cf. metachromia
hipposulfate C: from the marine sponge spongia irregularis collected in papua new guinea
hippuric acid: rn given refers to parent cpd; structure in merck index, 9th ed, #4591
hippuryl-L-lysine hydrolase: cleaves basic c-terminal amino acids & hydrolyses hippuryl-l-lysine
hippuryl-glycyl-glycine: rn given refers to parent cpd; n1 from 9th ci form index
hippuryl-histidyl-leucine: synthetic substrate for angiotensin converting enzyme; used in affinity chromatography
hippuryl-phenylalanyl-arginine: ; rn given refers to (l-phe,l-arg)-isomer
hipr-1 protein, C elegans: genbank u79734, genbank t08283; refseq nm_066524.3
hiracin JM79: a sec-dependent bacteriocin produced by enterococcus hirae dch5, isolated from mallard ducks (anas platyrhynchos); genbank dq664500
hirsein A: from thymelaea hirsuta, inhibits melanogenesis in b16 melanoma cells
hirsein B: from thymelaea hirsuta, inhibits melanogenesis in b16 melanoma cells
hirsutanone: from methanolic extract of the aerial parts of viscum cruciatum (viscaceae)
hirsutanonol: a diarylheptanoid from the bark of alnus hirsuta var. sibirica; inhibits cyclooxygenase-2 expression
hirsutatin A: from a culture filtrate of the insect pathogenic fungus hirsutella nivea
hirsutatin B: from a culture filtrate of the insect pathogenic fungus hirsutella nivea
hirsuteine: ; rn given refers to parent cpd; isolated from uncaria rhynchophylla
hirsutellide A: a cyclohexadepsipeptide isolated from a cell extract of the entomopathogenic fungus hirsutella kobayasii
hirsutellone F: a dimer of antitubercular alkaloid from the seed fungus trichoderma species bcc 7579
hirsutenol A: tricyclic sesquiterpene metabolite from the culture broth of the mushroom stereum hirsutum (stereaceae)
hirsutenol B: tricyclic sesquiterpene metabolite from the culture broth of the mushroom stereum hirsutum (stereaceae)
hirsutenol C: tricyclic sesquiterpene metabolite from the culture broth of the mushroom stereum hirsutum (stereaceae)
hirsutenone: inhibits upregulation of cox-2 and mmp-9 as induced by 12-o-tetradecanoylphorbol-13-acetate; isolated from the plant alnus hirsuta
hirsutide: cyclic tetrapeptide from a spider-derived entomopathogenic fungus, hirsutella sp
hirsutine: isolated from uncaria rhynchophylla; rn given refers to (3beta,16e)-isomer
hirtusneanoside: o-deoxyglycoside of a dimeric tetrahydroxanthone from the lichen usnea hirta
hirudin (42-63): a thrombin inhibitor peptide isolated from hirudineria manillensis
hirudin -like fusion protein 8067, human: hirudin-like fusion protein can activate human plasminogen and retain the function of thrombin inhibition
hirudin HV1: potent protease inhibitor; contains 65 amino acids, six of which are cysteine residues; mw 7 kda; amino acid sequence given in first source
hirudin HV2: potent protease inhibitor; contains 65 amino acids; mw 7 kda; amino acid sequence given in first source
hirudin HV3: potent protease inhibitor; contains 66 amino acids; mw appr 7 kda; amino acid sequence given in first source
hirudin PA: protein related to hirudin; amino acid for hirudin pa (54-66) given in first source; blocks thrombin's cleavage of fibrinogen; sulfation of the tyr(64) amino acid resulted in increased potency
hirudisin: hirudin variant with residues 32-35 replaced by arg-gly-asp-ser (rgds)
hirullin P18: 61 amino acid residues given in first source; from the leech, hirudinaria manillensis; has potent antithrombin activity
hirulog 3-thrombin complex: hirulog 3 is a synthetic peptide inhibitor in the hirulog class with beta-homo-arg at position 3'
hirulog-B2: d-cyclohexylalanine substituted in the first position of hirulog-1; more potent than hirulog-1
hirunorm: a 26-amino acid peptide; differs from hirunorm iv in the second amino acid - val(2) instead of arg(2); amino acid
hirunorm IV: a 26-amino acid peptide; differs from hirunorm v in the second amino acid - arg(2) instead of val(2); amino acid
hirustasin: from leech hirudo medicinalis; 55 amino acid residues; 27 - 32% sequence identity to the 1st and 2nd domains of antistasin respectively; amino acid sequence given in first source; genbank p80302
hirutonin-2: an analog of (d)phe-pro-arg-gly-hirudin(49-65); binds to thrombin active site and forms a complex
hirutonin-6: binds to thrombin active site and forms a complex; hirutonin-6 & -2 complexes are isomorphous
hisactophilin protein, Protozoan: histidine-rich actin-binding protein from dictyostelium discoideum; mw 17kda; amino acid sequence given in first source
hispidol A 25-methyl ether: isolated from ponciri immaturus fructus
histaglobulin: used in complex treatment of viral hepatitis; see also histaglobin; no other info available 1/8/81
histamine H3R antagonist 2-18: has anti-convulsant effect in mice
histamine dehydrogenase, Nocardioides simplex: 6-s-cysteinyl flavin mononucleotide-containing homodimeric enzyme that catalyzes oxidative deamination of histamine; has been sequenced
histamine-bovine serum albumin conjugate: modifies histamine h2 receptor activation mechanism
histamine-releasing peptide: can be formed during the inflammatory response by the action of enzymes secreted by the participating cells of inflammation when subsequently incubated with mammalian albumins; amino acid sequence given in first source
histidine N-acetyltransferase: synthesizes nalpha-acetyl-l-histidine from l-histidine and acetylcoenzyme a
histidine permease, Bacteria: hisp, hism & hisq are membrane proteins found in histidine permease (the hisqmp2 complex); also contains the histidine-binding protein hisj
histidine rich basic peptide (Aplysia): mw 4.9kda; from aplysia neurons r3-14
histidine rich basic peptide precursor (Aplysia): 85 amino acid residues given in first source
histidine triad nucleotide-binding protein, mammals: is a universally conserved enzyme that hydrolyzes amp linked to lysine
histidine triad protein: has adenosine monophosphoramidase activity; a small protein with a histidine triad (hxhxh, where x is hydrophobic); present in prokaryotes, yeast, plants and mammals; the function of hit is unknown except for the bovine protein which inhibits protein kinase c in vitro; refseq nm_138571 (human)
histidine-2 ferredoxin: a synthetic ferredoxin of clostridium pasteurianum with tyrosine-2 replaced by histidine
histidine-rich, sulfur-poor protein, rat: in cutaneous epidermal granular cell of newborn rat
histidinehydroxamic acid: rn given refers to cpd without isomeric designation
histidinoalanine: cross-linking amino acid in calcified tissue collagen; rn given refers to (l)-isomer
histidinohydroxylysinonorleucine: major cross-link of skin collagen in patients with amyotrophic lateral sclerosis
histidinomycin: from a streptomyces h 878-my 1
histidyl(7)-corazonin: an 11 amino acid color-inducing neuropeptide from locusts
histidyl-arginyl-alanyl-tryptophyl-phenylalanyl-lysinamide: msh antagonist; amino acid
histidyl-asparaginyl-glutamyl-leucine: signal for er or cis-golgi localization
histidyl-glutamyl-alanyl-prolyl-isoleucine: enkephalin antisense peptide
histidyl-glutamyl-tryptophyl-seryl-tyrosyl-leucyl-alanyl-prolyl-tyrosyl-prolyl-tryptophyl-phenylalanine: a tumor-cell specific peptide
histidyl-phenylalanyl-arginyl-tryptophanamide: binds melanocortin receptors
histidyl-phenylalanyl-prolyl-glycyl-proline: a metabolite of semax peptide
histidyl-proline diketopiperazine: biologically active cpd to which thyrotropin-releasing hormone (trh) is metabolized; structure; rn given refers to cpd without isomeric designation
histidyl-seryl-tryptophyl-arginyl-histidyl-phenylalanyl-histidyl-threonyl-leucyl-glycyl-glycyl-glycine: has antiangiogenic activity; acts on mcp-1
histidyl-threonyl-seryl-threonyl-tyrosyl-tryptophyl-tryptophyl-leucyl-aspartyl-glycyl-alanyl-proline: inhibits binding of lethal factor to anthrax protective antigen pa63
histin protein, Histoplasma capsulatum: rna polymerase inhibitor isolated from histoplasma capsulatum; do not use /antag
histo-blood group B transferase: catalyzes transfer of galactose from udp-galactose to glycoproteins and glycolipids; differs from a transferase by four amino acid residues
histochrome: a water-soluble natural pigment found in sea urchins; promotes stabilization of blood cell function & structure; reduces rbc & platelet aggregation
histocompatibility antigen 37: from t1a region of h-2d mouse mhc; amino acid sequence given in first source; related to histocompatibility antigen t10c
histocompatibility antigen DLA: major histocompatibility antigen of the dog
histocompatibility antigen T10b: encoded by b allele of t10 gene; related to antigens t10(129) & t27b; amino acid sequence given in first source
histocompatibility antigen T10c: from t1a region of h-2d mouse mhc; amino acid sequence given in first source; related to histocompatibility antigen 37 or t18d
histocompatibility antigens RT, rat: major histocompatibility complex of the rat; the classic class i mhc antigens are encoded by the rt1.a region, class ii by rt1.b & rt1.d regions, and medical transplantation antigens by the rt1.c region; has been sequenced
histogranin: nmda receptor antagonist isolated from bovine adrenal medulla; amino acid sequence given in first source
histogranin (7-10), cyclo(Ala(8)-Tyr(9)-Arg(10))-: has analgesic activity
histogranin (7-10), cyclo(p-Cl-Phe(8)-Tyr(9)-Arg(10))-: has analgesic activity
histolyn CYL: yeast phase reagent employed as antigen in enzyme immunoassay to detect antibody to histoplasma capsulatum in sera
histolysain: cysteine proteinase from entamoeba histolytica; active against cartilage proteoglycan and kidney glomerular basement-membrane collagen
histone DNA binding protein-1: sequence-specific dna-binding protein that interacts with the hexameric sequence acgtca; from wheat; see also records for hbp-1a & hbp-1b
histone H2B type 1-A: present in nuclei of round spermatids; carboxyl terminus contains a region rich in hydrophobic amino acids; not found in mature sperms; present & functioning only during restricted period of spermatogenic development; has been sequenced
histone HMf: hmfa and hmfb differ at only 12 of 68 or 69 positions; amino acid sequence given in first source
histone acetyltransferase type B complex: acetylates histone h4 at lysines 5 and 12; amino acid sequence of human (hshat1p) and saccharomyces cerevisiae (schat1p) enzymes in first source; genbank t78280 (human)
histone demethylase KDM3a, rat: refseq nm_175764
histone h2b kinase: 96 kda serine kinase from xenopus that phosphorylates histone h2b; a component or target of the raf-mek-erk pathway
histone methyltransferase Set5, S cerevisiae: s-adenosylmethionine-dependent methyltransferase; refseq nm_001179338.1
histone-like protein HU, bacteria: a dna-binding protein from many bacteria that stimulates the enzymatic replication of duplex dnas of recombinant phages & plasmids; do not confuse with vertebrate neuronal hu protein
histosol: proprietary mixture of synthetic aromatic hydrocarbons forming an extremely nonpolar organic solvent
histrionicotoxin: toxin isolated from colombian frog, dendrobates histrionicus
hitA protein, Lactobacillus brevis: an integral membrane protein with 11 putative trans-membrane domains and a binding protein-dependent transport signature of a non-atp binding membrane transporter common to several prokaryotic and eukaryotic transporters; from lactobacillus brevis; amino acid
hiwi protein, rat: an age-related protein expressed in testis and epididymis
hlFVII-LDP-AE fusion protein: an antineoplastic agent that targets tumor cells that overexpress tissue factor
hlb protein, Staphylococcus aureus: an exotoxin that attack blood cell membranes and cause cell rupture; genbank x61716
hlyA protein, Listeria monocytogenes: from listeria monocytogenes; ivanolysin o from l. ivanovii and seeligerolysin o from l. seeligeri have been sequenced (biochim biophys acta 1992;1130(1):81-4); sulfhydryl-activated toxin; is able to lyse cholesterol containing membranes; can be reversibly inactivated by oxidation; cholesterol is the receptor for the binding of these toxins to eukaryotic cell membranes
hlyE protein, E coli: silent hemolysin from e. coli; base
hlyU protein, Vibrio cholerae: amino acid sequence given in first source; upregulates the hemolysin hlya; genbank no. x66866
hmp protein, E coli: soluble 44 kda protein containing highspin b-type haem & fad; homologous to family of flavoprotein oxidoreductases; has dihydropteridine reductase and flavin reductase activity; has been sequenced
hmpX protein, Bacteria: isolated from erwinia chrysanthemi; amino acid ; genbank x75893
hmt1 protein, S pombe: an atp-binding cassette-type transport protein from s. pombe; do not confuse with hmt1 protein, s cerevisiae which is a protein-arginine n-methyltransferase
hmw protein, Drosophila: coiled-coil domain protein; refseq nm_142457
hnRNP A-B related protein, cat: from cat, binds to sequences in the feline parvovirus ssdna genome
hnRNP I-related RNA transport protein VgRBP60, Xenopus: from xenopus, may have role in cytoplasmic rna localization
hnRNPA3 protein, rat: a major a/b type heterogeneous-nuclear ribonucleoprotein (hnrnp); refseq nm_198132
hnRNPUL2 protein, human: refseq nm_001079559
hns protein, E coli: heterodimeric hu protein associated with the escherichia coli nucleoid shares some properties with histones and hmg proteins
hob1 protein, S pombe: homolog of mammalian bin1; required for the response to starvation or genotoxic stress
hoepixin: combination bath in psoriasis treatment of dithranol, salicylic acid, castor oil, coal tar, lanolin
hog peanut lectin: specific for terminal nonreducing n-acetyl-d-galactosamine groups; mw 135kda
hoiamide B: neurotoxic compound from two different collections of marine cyanobacteria obtained in papua new guinea
hoiamide C: neurotoxic compound from two different collections of marine cyanobacteria obtained in papua new guinea
hoiamide D: inhibits the p53 and mdm2 interaction; has antineoplastic activity; isolated from the cyanobacterium symploca
hoip protein, Drosophila: accelerates polyq-induced neurodegeneration in drosophila; refsec nm_079975.2
holD protein, E coli: encodes the psi subunit of pol iii, a subunit of the gamma complex
holTW protein, Staphylococcus phage Twort: class ii holin; amino acid
holin protein, Listeria monocin: from cryptic prophage (monocin) in listeria; 95 amino acids, mw 10.1 kda; amino acid sequence given in first source; genbank x89234
holin t protein, Enterobacteria phage T4: amino acid ; genbank y00408
holmium-1,4,7,10-tetraazacyclododecane-N,N',N'',N'''-tetrakis(methylenephosphonic acid): used as mri contrast agent
holo-(acyl-carrier-protein) synthase: isolated from streptomyces, genbank af222693
holocarboxylase synthetases: consider ec 6.3.4.9, ec 6.3.4.10, ec 6.3.4.11 or ec 6.3.4.15
holochrome protein, Rhodospirillum rubrum: pigment protochlorophyllide-protein complex
holocyclotoxin: from salivary glands of australian parasitic tick ixodes holocyclus
hololactoferrin, human: the interlobe peptides of human hololactoferrin and apolactoferrin showed only 75.5 % tridimensional similarity, indicating that iron uptake affects the three-dimensional structure of the interlobe chain
holotricin 1 protein, Holotrichia diomphalia: a sapecin homolog from the hemolymph of immunized larvae of a coleopteran, holotrichia diomphalia; mw about 6.5 kda; amino acid sequence given in first source
holotricin 2 protein, Holotrichia diomphalia: isolated from holotrichia diomphalia larvae; amino acid ; genbank d13745
holotricin 3 protein, Holotrichia diomphalia: from hemolymph of the coleopteran insect, holotrichia diomphalia larvae; amino acid sequence given in first source; genbank d13744
homaline: from the leaves of an african homalium species and homalium pronyense guillaum (flacourtiacae)
homatropine: minor descriptor (75-86); was see under belladonna 1963-68 search tropanes 1969-74 & belladonna 1966-68; on line & index medicus search tropanes (75-86); rn given refers to endo-(+-)isomer
homatropine methylbromide: rn given refers to bromide (endo-(+-))-isomer
homaxinolide A: cytotoxic metabolite from a marine sponge homaxinella sp.
homaxinolide B: cytotoxic metabolite from a marine sponge homaxinella sp.
homaxinolide C: cytotoxic metabolite from a marine sponge homaxinella sp.
homaxinone A: cytotoxic metabolite from a marine sponge homaxinella sp.
homeobox A1 protein: induced by retinoic acid in mcf7 breast cancer cells
homeobox protein HOXA13: refseq nm_008264 (mouse); nm_000522 (human)
homeobox protein HOXA9: the expression of hoxa9 is activated by proviral integration in bxh-2 myeloid leukemias; refseq nm_152739 (human); nm_010456 (mouse)
homeobox protein PITX1: binds to pituitary-specific pou domain protein (pit-1); expressed in primordial rathke's pouch, oral epithelium, first branchial arch, duodenum, and hindlimb; ptx - pituitary homeo box 1; a bicoid-related protein involved in transcription of pro-opiomelanocortin gene; refseq nm_011097 (mouse); nm_002653 (human); nm_053624 (rat)
homeobox protein PITX3: refseq nm_008852 (mouse); nm_019247 (rat); nm_005029 (human)
homeobox-leucine zipper protein ATHB-4, Arabidopsis: refseq nm_130055
homeodomain protein, Schizophyllum commune: the aalpha mating locus of s. commune encodes five dissimilar multiallelic homeodomain proteins, y1, y3, y4, z3 & z4; rn refers to y1; amino acid sequence given in first source
homeotic protein Hox 1.7 (clone GPK5), guinea-pig: function of protein unknown 4/92; amino acid sequence given in first source
hominicin peptide, Staphylococcus hominis: an antimicrobial peptide
homo-gamma-linolenylethanolamide: found in brain; binds to the cannabinoid receptor; rn given for (z,z,z)-isomer
homoaconitate hydratase: catalyzes conversion of 2-hydroxybutane-1,2,4-tricarboxylic acid to but-1-ene-1,2,4-tricarboxylic acid
homoanatoxin: ; potent nicotinic agonist; analog of anatoxin-a from cyanobacteria
homobatrachotoxin: from pitohui dichrous; toxic substance that can function as a defensive chemical
homobotcinolide: inhibits etiolated wheat coleoptile growth; also affects othes plants like corn and tobacco; isolated from botrytis cinerea
homobrassinolide: ; rn given refers to (2alpha,3alpha,5alpha)-isomer)
homocysteine alpha,gamma-lyase: a pyridoxal phosphate-dependent enzyme that catalyzes the conversion of homocysteine to alpha-ketobutyrate, dihydrogen sulfide, and ammonia
homocysteine cystathionine gamma-synthase: homocysteine & cystein yield cystathionine & h2s
homocysteine desulfhydrase: catalyzes the breakdown of homocysteine to hydrogen sulfide, ammonia & 2-oxobutanoate
homocysteine-thiolactonase, human: detoxifies homocysteine-thiolactone in blood and could thus delay the development of atherosclerosis
homodestruxin B: a cyclodepsipeptide; isolated from alternaria brassicaea
homogenin protein, chicken: from auditary epithelium of chick embryos; has 75% & 61% identity with gelsolin & adseverin, respectively; genbank af042795
homogentisate geranylgeranyl transferase, Hordeum vulgare: catalyzes the conversion of geranylgeranyl pyrophosphate and homogentisate to 2-methyl-6-geranylgeranylbenzoquinol
homogentisate solanesyltransferase, Arabidopsis: catalyzes the conversion of homogentisate and solanesyl diphosphate to yield 2-demethylplastoquinol-9; refseq nm_112028
homohalichondrin B: form marine sponge halichondria okadai; binds the vinca domain of tubulin
homoisomelodienone: ; a bioactive heptene isolated from melodorum fruticosum
homolycorine: irritant isolated from daffodils (narcissus pseudonarcissus l., amaryllidaceae)
homomelodienone: ; a bioactive heptene isolated from melodorum fruticosum
homopseudopteroxazole: antimycobacterial diterpenene alkaloid from pseudopterogorgia elisabethae
homopterocarpin: an insect antifeedant isolated from pterocarpus marcocarpus
homosarkomycin: ; (cas index guide 1987-1991 p998g lists homosarkomycin as cyclohexane carboxylic acid, 2-methylene-3-oxo-)
homoseongomycin: from the marine bacterium salinispora pacifica dpj-0019
homospermidine synthetase: proposed mechanism-schiff base formed between putrescine & its oxidation product, 4-aminobutyraldehyde, then reduced to sym-homospermidine; requires nad
homotarsinin: anitbiotic peptide derived from skin of phyllomedusa tarsius anurans (leaf frog)
honaurin A: an antiinflammatory agent that inhibits bacterial quorum sensing; isolated from leptolyngbya crossbyana
honaurin B: an antiinflammatory agent that inhibits bacterial quorum sensing; isolated from leptolyngbya crossbyana
honaurin C: an antiinflammatory agent that inhibits bacterial quorum sensing; isolated from leptolyngbya crossbyana
hongbeiyegen: from the the root of alchornea trewioides; has therapeutic effect on alcohol-induced rat hepatic fibrosis
hongjingtian: manufactured from extracts of rhodiola wallichiana var. cholaensis
hook protein, Drosophila: a component of the endocytic compartment that plays a role in the endocytosis of transmembrane ligands; has a central coiled-coil domain; amino acid sequence given in first source; genbank u48362
hook3 protein, mouse: implicated in cellular trafficking & target of salmonella spic protein; refseq nm_207659
hookeroside A: biologically active (inhibits pancreatic lipase) triterpenoid saponin from scabiosa tschiliensis
hookeroside B: biologically active (inhibits pancreatic lipase) triterpenoid saponin from scabiosa tschiliensis
hop protein, Drosophila: hop can refer to two distinct drsosophila gene symbols. the other hop gene is hsp70/hsp90 organizing protein homolog. refseq nm_078564
hopeahainol A: an acetylcholinesterase inhibitor from hopea hainanensis
hopeanol: polyphenol from hopea exalata and h hainanensis; cytotoxic against a variety of tumor cells
hopeanolin: an unusual resveratral trimer with an ortho-quinone nucleus from the stem bark of hopea exalata; has antifungal activity and inhibitory effects against jack bean urease
hopeaphenol A: from the stem bark of vatica oblongifolia (dipterocarpaceae)
hopenyl palmitate: triterpene ester from the twigs of brachylaena ramiflora from the madagascar rainforest (asteraceae)
hopromine: from the leaves of an african homalium species and homalium pronyense guillaum (flacourtiacae)
hor protein, bacteria: hor - homolog of rap; from many bacteria, belongs to a superfamily of proteins regulating diverse phyiological processes in bacterial pathogens; amino acid
hordatine M: biosynthetic product of coupling agmatine and 4-hydroxycinnamoyl-coa and subsequent dimerization; phytoalexin isolated from uninfected barley seedlings
hordoindoline B protein, Hordeum vulgare: isolated from barley; genbank aj276143
hormaomycin: antibacterial and antimalarial peptide from streptomyces griseoflavus
horminone: rn refers to (4bs-(4balpha,8abeta,10beta))-isomer; from root of salvia officinalis
hormonin: estrogen replacement; each tablet contains 600 ug micronized 17beta-estradiol, 270 ug estriol and 1.4 mg estrone
hormothamnin A: from hormothamnion enteromorphoides; cyclic undecapeptide
hornetin: lethal protein of the hornet vespa flavitarsus venom; mw 32 kda
horridum toxin, Heloderma horridum: has arginine ester hydrolase activity; isolated from the venom of the lizard heloderma horridum horridum; amino acid
horseradish peroxidase-coupled gold: a horseradish peroxidase germ agglutinin coupled with gold particles; used as a retrograde tracer
hortensin flavonoid: ; isolated from the flowers of millingtonia hortensis l
host cell factor, Drosophila: a single drosophila melanogaster host cell factor ortholog (dhcf); 1500 residues in size, intermediate between hcf-1 and hcf-2 and contains an n-terminal kelch domain, and c-terminal fniii domain both of which show a very high degree of identity, and a central region of some 700 residues with more limited homology: genbank aj320236
hostoxin-1, Hoplocephalus stephensi: a postsynaptic neurotoxin from the venom of the stephen's banded snake (hoplocephalus stephensi); mw 6660 da; has high sequence homology with other elapid short-chain neurotoxins
hothead protein, Arabidopsis: a pattern of non-mendelian inheritance in the hothead (hth) mutant of arabidopsis thaliana, in which a plant homozygous at a particular locus upon self-crossing produces progeny that are 10% heterozygous
houttuyninum: stable form of houttuynine (derived from houttuynia cordata) through the addition of a sulfur group; inhibits bacterial growth, improves the immune response, and an anti-inflammatory
houttuynoid A: flavinoid compound extracted from houttuynia cordata with antiviral activity against herpes simplex virus (hsv)
hovenidulcioside A1: isolated from seeds & fruit of hovenia dulcis
hovenidulcioside A2: dammarane from the seeds and fruit of hovenia dulcis, constituents of the chinese medicine hoveniae semen seu fructus
hovenidulcioside B1: dammarane from seeds & fruit of hovenia dulcis
hovenidulcioside B2: dammarane from seeds & fruit of hovenia dulcis
hovenitin I: from seed and fruit of hovenia dulcis; hovenitin i & ii are (2r,3r) & (2r,3s) isomers respectively; rn refers to hovenitin i
howiinin A: from the bark of goniothalamus howii merr. (annonaceae)
howiinol A: isolated from goniothalamus howii; ; do not confuse with ghm-10, gas hypoxic mixture of 90% n2 & 10% o2
hpaA protein, E coli: e coli protein is involved in the catabolism of 4-hydroxyphenylacetate
hpcG protein, E coli: involved in the meta-fission homoprotocatechuic acid pathway of escherichia coli; showed 36% amino acid sequence identity with the catechol pathway hydratase; amino acid sequence given in first source; genbank x81446
hphd-1 protein, C elegans: refseq nm_064363.4
hppy protein, Drosophila: an ste20 family kinase required for transport from endosomes to golgi; has been sequenced; refseq nm_166335
hr protein, rat: mw 127-kda; has 1182 amino acid residues; refseq nm_024364
hr44 antigen: from human retina; neural-specific; a membrane-associated type i antigen; mw 44 kda; amino acid sequence given in first source; genbank x91103
hrap protein, Capsicum annuum: hypersensitive response-assisting protein; amino acid
hrdA protein, Streptomyces coelicolor: from streptomyces coelicolor; has similarities to sigma factor; amino acid sequence given in first source
hrdC protein, Streptomyces coelicolor: from streptomyces coelicolor; has similarities to sigma factor; amino acid sequence given in first source
hrdD protein, Streptomyces: rna polymerase principal sigma factor; a transcription initiation factor that promotes the attachment of the rna polymerase to specific initiation sites; amino acid sequence given in first source
hrg protein, Drosophila: encodes a poly(a) polymerase, which controls the formation of the wing margin in drosophila melanogaster; refseq nm_001043097
hrg-2 protein, C elegans: hrg - heme-responsive gene-2; refseq nm_001307734.1
hrm protein, Drosophila: a member of the rna recognition motif (rrm) family of proteins; refseq nm_136330
hrmA protein, Pseudomonas syringae: from pseudomonas syringae pv. syringae 61 hrp gene cluster; mw 41.5 kda; amino acid sequence given in first source; may function as a regulatory protein; genbank l14926
hrp23 protein, Chironomus tentans: from chironomus tentans; molecular mass of 20-kd with a single rna-binding domain and glycine-arginine-serine-rich auxiliary domain; amino acid
hrp65 protein, Chironomus tentans: similar to hnrnpproteins and splicing factors; it does not bind to nascent pre-mrna and is not part of the pre-mrnp itself; amino acid
hrpA protein, E coli: atp-dependent helicase; similar to yeast prp16 and prp22 (deah family rna helicase); belongs to the deah family; an rna helicase-like protein; from e. coli; mw 146 kda; genbank d42105
hrpB protein, Ralstonia solanacearum: 477 amino acid residues; a positive regulator of hypersensitive response genes involved in plant pathogenicity; also a positive regulator of its own synthesis in minimal medium; from pseudomonas solanacearum; amino acid sequence given in first source
hrpH protein, Pseudomonas syringae: hypersensitivity response secretion protein; amino acid sequence given in first source; from pseudomonas syringae pv. syringae 61
hrpI protein, Pseudomonas syringae: belongs to the superfamily of proteins assoicated with protein translocation; from pseudomonas syringae; mw 76,490 da; aa sequence given in first source; genbank l11582
hrpJ protein, Pseudomonas syringae: a hypersensitivity response secretion protein involved in the secretion of a proteinaceous elicitor of the hypersensitivity response in plants and also required for pathogenicity on host plants; from pseudomonas syringae; mw 37,710 da; aa sequence given in first source; genbank l11281
hrpS protein, Pseudomonas syringae: pathogenicity locus probable regulatory protein; found in a pathogenicity locus from pseudomonas syringae; homologous to a highly conserved domain of several procaryotic regulatory proteins; amino acid sequence given in first source
hsc70-3 protein, Lycopersicon esculentum: isolated from lycopersicon esculentum; involved in protein folding and assembling/disassembling of protein complexes; amino acid ; genbank l41253
hscA protein, E coli: member of the hsp70 protein class; from escherichia coli; mw 66 kda; genbank u05338
hscC protein, E coli: a dnak homologue of escherichia coli, encodes a 62-kda protein; amino acid
hsf1 protein, zebrafish: zebrafish heat shock transcription factor; amino acid ; refseq nm_001313736
hshB protein, Xanthomonas oryzae: a hydrolase with a putative signal peptide, which is a homolog of imidazolonepropionase; a pathogenicity-related gene hshb gene product
hsiao cheng chi tang: composed of rhei rhizoma, aurantii fructus immaturus, and magnoliae cortex; contains gallic acid, sennoside a & b, naringin, hesperidin, honokiol, magnolol and emodin
hsp-12.2 protein, C elegans: small heat-shock protein; amino acid ; refseq nm_066375.6
hsp17.6 G1 protein, Helianthus annuus: a small heat-shock protein from sunflower; amino acid ; genbank z95153
hsp17.7 protein, Helianthus annuus: a small heat-shock protein isolated from sunflow helianthus annuus; amino acid ; genbank u46545
hsp18 protein, bacteria: genbank x65276 (clostridium acetobutylicum)
hsp18.6 protein, Helianthus annuus: small heat-shock protein isolated from sunflower helianthus annuus; genbank u46544
hsp60 protein, Tetrahymena: a bifunctional 14-nm filament protein with roles as a cytoskeletal protein in cytoplasm and as a citrate synthase in mitochrondria; partial amino acid
hsp60B protein, Drosophila: from drosophila melanogaster; essential for the spermatid individualization process; amino acid ; refseq nm_080186
hsp70.4 protein, Leishmania major: a chaperone protein isolated from leishmania major; related to hsp70; amino acid sequence given in first source; genbank x69825
hsp90aa1.1 protein, Xenopus: refseq nm_001092129
hsr203J protein, Nicotiana tabacum: has serine esterase activity; activation is rapid, highly localized & specific for incompatible plant/pathogen interactions; from tobacco, nicotiana tabacum; amino acid sequence given in first source; genbank x77136
htl protein, Drosophila: involved in migration of early mesodermal cells; amino acid sequence given in first source; refseq nm_169784
htrA protein, Bacillus anthracis: refseq yp_002867792
htrI protein, Halobacterium salinarium: from halobacterium salinarium; a transducer protein for sensory rhodopsin i signals; has been sequenced
hts protein, Drosophila: homologous to adducin; localized in ring canals of drosophila oocyte; amino acid ; refseq nm_057529
hu3S193-N-acetyl gamma calicheamicin dimethyl hydrazide: targets lewis(y) antigen in antibody-targeted chemotherapy
hu5C8 antibody: humanized cd154-specific monoclonal antibody, prevents acute rejection of primary skin allografts in nonhuman primates
huB3F6-SPDB-DM4 immunoconjugate: used against cripto positive tumors; consists of humanized monoclonal antibody bf36 linked to maytansinoid derivative dm4
huachansu: from dried toad venom from the skin glands of bufo gargarizans or b. melanostictus; has been used in the treatment of various cancers in china
huai hua san: consists of four herbs: flos sophorae (the dried flower bud of sophora japonica l.), cacumen platycladi (the dried branches and leaves of platycladus orientalis (l.) franco), fructus aurantii (the dried immature fruit of citrus aurantium l.) and herba schizonepetae (the dried overground parts of schizonepeta tenuifolia briq.)
huai qi huang: contains trametes robiniophila murr, wolfberry fruit, and polygonatum; ameliorates proteinuria and hematuria in mild iga nephropathy patients
huang-qi san: composed of three traditional chinese medicines (astragali radix, pueraria radix and cortex mori radicis)
huanglian: an ethanolic extract of coptis teeta; has anti-diarrheal activity
huanglian xiangru: contains: xiangru (moslae chinensis maxim.), houpu (magnoliae officinalis rehd.et wils.) and huanglian (coptidis chinensis franch.); frequently used for treating cold in summer and summer heat-dampness, also has anti-h1n1 influenza effects
huanglian-jie-du decoction: demonstrated to be effective to treat ischemic stroke
huannao yicong: used to treat alzheimer's disease; prepared from radix polygoni multiflori, radix ginseng, rhizoma chuanxiong, rhizoma acor tatarinowii, and rhizoma coptidis
huanshuai: a renal protective agent that regulates vegf expression; consists of radix ginseng, radix astragali seu hedysari, radix angelicae sinensis, rhimoza lugistici chuanxiong, radix paeoniae rubra, caulis spatholabi, herba plantaginis, poria, rhixoma alismatis, and radix rhixoma rhei
huashi baidu: consists of glycyrrhiza, apricot kernel, agastache rugosus, magnolia officinalis, atractylodes, amomum tsao-ko, pinellia ternate, poria cocos, rhubarb, astragalus, lepidium seed, red peony root, and ephedra
huatan tongluo: composed of six herbs, including bile arisaema, semen persicae, flos carthami, sinapis alba, bombyx batryticatus, and paeonia alba
huaxian: may be helpful in treating bleomycin-induced alveolitis and pulmonary fibrosis
huayu zhitong: for treatment of distal radius fracture; list of components in first source
huazhongilexone-7-O-glucopyranoside: isolated from ilex hainanensis
huchang jiedu: used to treat chronic severe hepatitis b; consists of rhizoma rhei, radix paeoniae rubra, poria, rhizoma bletillae, and radix glycyrrhizae
hugan qingzhi: used for prevention and treatment of nonalcoholic fatty liver; consists of rhizoma alismatis, fructus crataegi, pollen typhae, folium nelumbinis, and radix notoginseng sanchi
human X polypeptides: polypeptides specific for human x chromosomes; have been isolated and characterized; mws given in first source
human chorionic gonadotropin-cholera toxoid conjugate: cholera toxoid conjugate of natural or recombined hcg; containing a hcg beta subunit with cholera toxoid and a lh alpha subunit of human or another species; used as antifertility vaccine
human chorionic gonadotropin-tetanus toxoid: tetanus toxoid-conjugated natural or recombined hcg; containing a processed hcg beta subunit with tetanus toxoid and a lh alpha subunit of human or another species; used as antifertility vaccine
human cytomegalovirus antigen p55-52: major hcmv antigen; amino acid sequence has been determined
human cytomegalovirus protease UL80: ul80 encodes a polyprotein, the c-terminal portion being a 45-kda assembly protein and the n-terminal portion being the protease; isolated from human cytomegalovirus virus; has been sequenced
human cytomegalovirus protein pp28: cloned from pp28 towne gene; has been sequenced; mw 28kda
human endogenous retrovirus K10 protease: amino acid ; genbank af164613
human epithelial antigen-125: a biliary cell marker; an epithelial antigen; used in differential diagnosis of mesothelioma and adenocarcinoma
human foamy virus-env (502-536) peptide: has homology to several isolates of human retroviruses; amino acid sequence given in first source
human growth hormone isohormone D: from limited enzymatic cleavage in large disulfide loop of hgh
human growth hormone isohormone E: from limited enzymatic cleavage in large disulfide loop of hgh
human inhibin-like peptide (1-31): peptide containing 31 amino acids with inhibin-like activity; amino acid sequence given in first source
human insulin-like-growth-factor-I (21-40): amino acid sequence given in first source; used to test a theory of molecular recognition
human intravenous vaccinia immune globulin: purified gamma globulin (igg) fraction of human plasma containing antibodies to vaccinia virus. it is indicated for treatment of severe complications of smallpox vaccine
human lactoferrin peptide 2: synthetic peptide that corresponds to charged region of loop; amino acid
human leukemia protein LD4: 67% identical to rho gdi; has been sequenced
human neutrophil peptide 4: was sy to defensins; do not confuse with peptide np-4 (rabbit)
human papillomavirus type 18 L1 VLP vaccine: vlp - virus-like particle; each dose consists of 80 microgm of hpv18 l1 vlp formulated with 450 microgm of amorphous aluminum hydroxyphosphate sulfate adjuvant in a buffer solution
human papillomavirus vaccine, L1 type 16, 18: vaccine containing l1 capsid proteins from types 16 and 18 of hpv (alphapapillomavirus)
human papillomavirus vaccine, TA: a recombinant vaccinia virus; encodes hpv types 16 and 18, e6 and e7 proteins; used for immunotherapy of cervical cancer
human parainfluenza virus type 1 nucleoprotein: a viral nucleoprotein of 524 amino acids; has been sequenced
human pituitary glycopeptide: 39 residue glycopeptide isolated from human neurohypophysis; may be part of the precursor of argipressin & neurophysin ii
human platelet antigen 1b: epitope of platelet glycoprotein iiia
human probombesin C-terminal peptide: found in lung small cell carcinoma with rabbit antiserum to the first (n-terminal) 21 amino acids of the predicted c-terminal peptide; diagram of peptide given in first source; reliable tumor marker & possible prognostic indicator for small cell carcinoma
human serum albumin, des-leucyl(585)-: a marker for chronic pancreatitis
human sperm antigen, 27 kDa: an inner acrosomal membrane protein of human sperm, defined by a monoclonal antibody with fertilization-blocking effect
human vascular endothelial growth factor-staphylococcal enterotoxin A fusion protein: has antineoplastic activity
human-specific STING agonist G10: a sting agonist that promotes an immune response against viruses
humanin: suppresses neuronal cell death induced by the swedish mutant of amyloid precursor protein; suppresses neuronal cell death induced by three different types of fad genes and amyloid beta; amino acid
humantenine: isolated from root of hu-man-teng (gelsemium elegans benth.)
humantenirine: isolated from root of hu-man-teng (gelsemium elegans benth.)
humantenmine: alkaloid from roots of hu-men-teng (gelsemium elegans banth.)
humicolin: a 38 kda extracellular thiol-containing serine protease from thermomyces lanuginosus
humimycin A: humimycin - human microbiome mycin; isolated from rhodococcus equi
humimycin B: humimycin - human microbiome mycin; isolated from rhodococcus erythropolis
humin: humic acid according to dorland; environ letters 3(1):1-12;1972 says it is a higher mw material, insoluble in both acid & alkali (humic acid is soluble in alkali)
humoral leukocyte adherence inhibition factor, human: mw 71,000 glycoprotein found in high concentration in serum of patients with lung cancer & smaller quantities in sera of other cancer types
humulene cyclase: catalyzes the cyclization of farnesyl pyrophosphate; probably by intramolecular electrophilic attack by c-1 bearing the pyrophosphate ester on c-11 of the terminal double bond to give a humulyl cation which is stabilized by deprotonation at c-9 to form all-trans humulene; mw 57 kda
hunanamycin A: antibiotic from a marine-derived bacillus hunanensis
hunterioside: a monoterpenoid indole alkaloid glycoside; isolated from hunteria zeylanica
huo luo xiao ling dan: has antihyperalgesic and anti-inflammatory activities
huogu II: used to treat osteonecrosis of the femoral head; consists of radix astragali, angelica sinensis, radix paeonia rubra, rhizoma ligustici chuanxiong, lumbricus, ramulus cinnamoni, and more
huoxue anxin: used to treat cardiovascular diseases; consists of radix salviae miltiorrhizae, panax pseudoginseng, ginkgo, and semen ziziphi spinosae
huoxue qianyang: helps reverse left ventricular hypertrophy in spontaneous hypertension rats
huoxuezhitong capsule: contains: chinese angelica root, notoginseng root, frankincense, borneol, ground beetle, native copper
hupA protein, E coli: hupa - hemoglobin utilization protein a; a hemoglobin-binding protein
hupC protein, Bacteria: from structural operon of rhizobium leguminosarum bv. viciae; mw 27.9 kda; has hydrogenase activity; amino acid sequence given in first source
hupF protein, Rhizobiales: has hydrogenase activity; identified in rhizobium leguminosarum and bradyrhizobium japonicum; amino acid sequence given in first source
hupK protein, Rhizobium leguminosarum: a hydrogenase-ancillary protein; isolated from rhizobium leguminosarum; has been sequenced
hupR1 protein, Rhodobacter capsulatus: hydrogenase transcriptional regulatory protein; from rhocobacter capsulatus; response regulator of the ntrc family required for hydrogenase expression; amino acid sequence given in first source; in conjunction with sigma-54, hupr1 acts a transcriptional activator; genbank m63670
hupehemonoside: ; isolated from fresh bulb of fritillaria hupehensis
hupehenine: commercially available antitussive and expectorant from fritillaria hupehensis
hupeheninoside: isolated from fritillaria hupehensis; ; mf: c33-h55-n-o7
hupehenisine: isolated from bulb of fritillaria hupehensis; mf: c27-h41-n-o3
huperphlegmine A: lycopodium alkaloid isolated from the aerial parts of huperzia phlegmaria; has moderate acetylcholinesterase inhibitory activity
huperphlegmine B: lycopodium alkaloid isolated from the aerial parts of huperzia phlegmaria; has moderate acetylcholinesterase inhibitory activity
huperzine A: rn given refers to 5r-(5alpha,9beta,11e)-isomer
huperzine B: chinese drug isolated from huperzia serrata; ; also isolated from phlegmariurus fordii
huperzine R: a 15-carbon lycopodium alkaloid from huperzia serrata (huperziaceae)
huperzinine C: lycodine type alkaloid with tricyclic structure from huperzia serrata
hurghadolide A: potent actin-microfilament disrupter from the red sea sponge theonella swinhoei
hurin protein, Hura crepitans: potent lymphocyte mitogen from seed of hura crepitans
hus1 protein, S pombe: required for s-m and dna damage checkpoints; genbank y09438
hushinone: from the buds of betula pubescens ssp. czerepanovii
huwentoxin I: amino acid sequence given in first source; isolated from the chinese bird spider selenocosmia huwena
huwentoxin II: isolated from the venom of the chinese bird spider, selenocosmia huwena; amino acid
huwentoxin IV, Selenocosmia huwena: a neuronal tetrodotoxin-sensitive sodium channel antagonist; amino acid sequence
huwentoxin-V, Ornithoctonus huwena: a neurotoxin from chinese tarantula ornithoctonus huwena venom that inhibits insect calcium channels; partial amino acid