NLK-NML/MeSH-CZ-2025-notes huggingface dataset:
4-(2-diethylaminoacetyl)-2,5,7,8-tetramethyl-3,4-dihydro-2H-benzo(1,4)oxazine-2-carboxylic acid ethyl ester: an antiarrythmia agent
4-(2-dimethylaminoethyl)-4,5,6,7-tetrahydro-7-(4-methoxyphenyl)-5-oxothieno(2,3-b)(1,4)thiazepin-6-yl acetate: thienodiltiazem is the ((+)-(6s,7s)-isomer); a calcium channel blocker
4-(2-dimethylaminophenyl)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)-1-piperazinehexanamide: a 5-ht7 receptor agonist
4-(2-diphenyl)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)-1-piperazinehexanamide: a 5-ht7 receptor agonist
4-(2-ethoxy-5-(4-ethylbenzyl)phenyl)-6-(hydroxymethyl)cyclohexane-1,2,3-triol: a sodium glucose cotransporter 2 (sglt2) antagonist
4-(2-ethyl-3-hydroxy-5-oxopyrrolidin-1-yl)-2-(trifluoromethyl)benzonitrile: a selective androgen receptor modulator
4-(2-fluoro-4-((((2-phenylacetyl)amino)thioxomethyl)amino)phenoxy)-7-methoxy-N-methyl-6-quinolinecarboxamide: inhibits both vegfr and met kinase
4-(2-fluoro-4-methanesulfonylphenyl)-3-(4-fluorophenyl)-5H-furan-2-one: a cox-2 inhibitor
4-(2-formyl-5-methoxymethylpyrrol-1-yl)butyric acid: isolated from bolbostemma paniculatum
4-(2-heptyloxy)-7-(3-hydroxycyclohexyl)indole: rn given from first source for (z)-isomer; rn not in chemline 9/86
4-(2-hydroxy-3-(4-(2-methoxyphenyl)piperazin-1-yl)propoxy)-9H-xanthen-9-one: an adrenergic beta-1 receptor antagonist
4-(2-hydroxy-3-(4-(2-methoxyphenyl)piperazine-1-yl)propoxy)-9H-xanthen-9-one: an adrenergic alpha1 antagonist
4-(2-hydroxy-3-(N-isopropylamino)propoxyimino)carane: ; rn given refers to the (1r-(1alpha,3e(r*),4beta,6alpha))-isomer
4-(2-hydroxy-3-(propan-2-ylamino)propyl)-1,7-dimethyl-8,9-diphenyl-4-azatricyclo(5.2.1.0(2,6))dec-8-ene-3,5,10-trione: has antineoplastic activity
4-(2-hydroxy-4-methoxyphenyl)-4-oxobutanoic acid: an antimalarial that inhibits orotidine 5'-monophosphate decarboxylase from plasmodium falciparum
4-(2-hydroxyphenyl)-1,5-benzodiazepin-2-one: an anticonvulsant
4-(2-hydroxyphenyl)but-3-en-2-one: inhibits lipopolysaccharide-induced expression of inducible nitric oxide synthase
4-(2-hydroxypropan-2-yl)-1-methylcyclohexane-1,2-diol: an antioxidant isolated from the roots of decalepis hamiltonii
4-(2-isocyanovinyl)phenyl alpha-L-rhamnopyranoside: isolated from the fermentation broth of a bacterial strain
4-(2-malonyl)phenylalanine: inhibits grb2 sh2 domain binding
4-(2-mercaptophenylcarboxamido)benzenesulfonamide: a carbonic anhydrase inhibitor
4-(2-methoxycarbonimidoylethyl)phenyl 10-methyacridinium-9-carboxylate: ; a chemiluminescent acridinium ester capable of reacting with proteins under mild conditions
4-(2-methoxyphenethyl)-1-(3-methoxyphenethyl)piperidine: a vesicular monoamine transporter-2 inhibitor
4-(2-methoxyphenylcarbamoyloxymethyl)piperidine-1-carboxylic acid tert-butyl ester: activates sk1 subtype small-conductance calcium-activated potassium channels
4-(2-methybutyryl)-4H-tomentosin: from carpesium macrocephalum, inhibits candida albicans biofilm formation and dimorphism
4-(2-methyl-1-pyrrolidyl)-7-chloroquinoline: formed by reaction of chloroquine with trichloroethyl chloroformate
4-(2-methylthiazol-4-yl)-N-(3,3,3-trifluoropropyl)benzamide: inhibitst ethr protein of mycobacterium tuberculosis
4-(2-methylthiophenyl)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)-1-piperazinehexanamide: a 5-ht(7) receptor agonist
4-(2-naphthylcarboxamido)phenoxyisobutyric acid: an antioxidant that inhibits advanced glycation end-product formation
4-(2-oxo-2,3-dihydrobenzimidazol-1-yl)piperidine-1-carboxylic acid (1-(3,5-dibromo-4-hydroxybenzyl)-2-oxo-2-(4-phenylpiperazin-1-yl)ethyl)amide: ; in text as wo98/11128
4-(2-oxo-3-(1H-tetrazol-5-yl)-2H-chromen-8-yloxy)butyric acid: ; rn from toxlit
4-(2-oxocyclohexyl)-2-hydroxy-buta-2,4-dienoic acid hydrolase: a serine hydrolase wich cleaves the alicyclic ring of tetralin; has been sequenced; genbank af204963
4-(2-phenyl-5,7-bis(trifluoromethyl)pyrazolo(1,5-a)pyrimidin-3-yl)phenol: a selective estrogen receptor modulator
4-(2-propynyloxy)-beta-nitrostyrene: rn given refers to cpd without isomeric designation
4-(2-pyridinyl)phenylacetohydrazide: inhibits copper-depleted bovine serum amine oxidase
4-(2-pyridylazo)resorcinol: rn given refers to parent cpd
4-(2-pyrrolidine)ethylspiro((dihydropyrazin-2,5-dione)-6,3'-(2',3'-dihydrothieno(2,3-b)naphtho-4',9'-dione)): has antineoplastic activity
4-(2-quinazolylazo)phenol: selective & sensitive reagent for copper assay
4-(2-succinimidoethylthio)phenyl 4-guanidinobenzoate: potently inhibits trypsin, plasmin and thrombin
4-(2-succinimidyloxycarbonylethyl)phenyl-10-methylacridinium-9-carboxylate: used in immunoassays
4-(2N-gardenamide)-n-butanoic acid: an iridiod isolated from gardenia volkensii
4-(3',3'-dimethylallyloxy)-5-methyl-6-methoxyphthalide: isolated from pestalotiopsis photiniae
4-(3',4'-dimethoxyphenyl)but-3-en-1-ol: uterine relaxant isolated from zingiber cassumunar roxb
4-(3',5'-dihydroxynonadecyl)phenol: an antioxidant isolated from heliotropium sinuatum
4-(3'-(1-adamantyl)-4'-hydroxyphenyl)-3-(3'-acetamidopropyloxy)cinnamic acid: induces apoptosis
4-(3'-(2'-chlorophenyl)-2'-propen-1'-ylidene)-1-phenyl-3,5-pyrazolidinedione: a dock2 inhibitor
4-(3'-(3'',5''-dimethylphenyl)ureido)phenyl sulfamate: a carbonic anhydrase ix inhibitor
4-(3'-(3',5'-dimethylphenyl)ureido)phenyl sulfamate: a carbonic anhydrase ix inhibitor
4-(3'-(myristoyloxy)propyl)-2,6-dioxodiethylenetriamine-1,1,7,7-tetraacetic acid gadolinium complex: lipophilic fatty acyl conjugated nmr contrast agent
4-(3'-(myristoyloxy)propyl)diethylenetriamine-1,1,7,7-tetraacetic acid gadolinium complex: lipophilic fatty acyl conjugated nmr contrast agent
4-(3'-di(2-bromoethyl)aminopropionyl)biphenyl: high affinity choline uptake was significantly decreased in a dose-dependent manner by this compound; ; rn given refers to parent cpd
4-(3'-di(2-chloroethyl)aminopropionyl)biphenyl: high affinity choline uptake was significantly decreased in a dose-dependnet manner by this compound; ; rn given refers to parent cpd
4-(3'-nitro-2'-pyridinesulfenyloxymethyl)phenylacetic acid: 3-nitro-2-pyridinesulfenyl group is a protective group which can be activated for peptide bond formation
4-(3,3,5,5-tetra-methyl-2,6-dioxo-4-oxylpiperazin-1-yl)phenylglycine: a spin label
4-(3,3-dimethyl-1-oxotridecyl)benzenesulfonic acid: photodegradable ionic detergent used to solubilize proteins
4-(3,3-dimethyl-1-triazeno)cinnamic acid: ; rn given refers to potassium salt
4-(3,3-dimethyl-1-triazeno)phenylbutyric acid: ; rn given refers to potassium salt
4-(3,3-dimethylbutylidene)glutamic acid: a glur5 ligand
4-(3,3-dimethylbutyrylamino)-3,5-difluoro-N-thiazol-2-ylbenzamide: an adenosine a2a receptor ligand
4-(3,4,4-trimethyl-5-oxo-2-thioxo-1-imidazolidinyl)-2-(trifluoromethyl)benzonitrile: a non-steroidal antiandrogen
4-(3,4,5-trimethoxybenzoyl)-2-phenylthiazole: a tubulin modulator and antineoplastic agent
4-(3,4,5-trimethoxyphenoxy)benzoic acid: has antineoplastic activity
4-(3,4-dichlorophenyl)-1-(1-(1-methylcyclopropanecarbonyl)piperidine-4-5 carbonyl)pyrrolidin-3-yl)methylcarbamic acid 4-fluoro-phenyl ester: a dual antagonist of both neurokinin-2 and neurokinin-3 receptors
4-(3,4-dichlorophenyl)-4,5-dihydrooxazol-2-ylamine: partial agonist of trace amine-associated receptor 1 (taar1)
4-(3,4-dichlorophenyl)-4-((dimethylamino)methyl)-1-methylcyclohexanol: a triple reuptake inhibitor of norepinephrine, dopamine, and serotonin
4-(3,4-diethoxyphenyl)-2-(4-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenoxy)butyl)-4a,5,8,8a-tetrahydro-2H-phthalazin-1-one: a dual pde3/pde4 inhibitor
4-(3,4-difluorophenyl)-6-methoxymethyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid (3-(4-(4-fluorophenyl)piperidin-1-yl)propyl)amide: an alpha(1a) receptor antagonist for the treatment of benign prostatic hyperplasia
4-(3,4-dihydro-2,4-dioxo-2H-1,3--benzoxazin-3-yl)butyric acid ethyl ester: a gaba prodrug
4-(3,4-dihydro-2,4-dioxo-2H-1,3-benzoxazin-3-yl)butyric acid: a gaba prodrug
4-(3,4-dihydroxybenzoyloxymethyl)phenyl-O-beta-D-glucopyranoside: an antioxidant isolated from origanum vulgare
4-(3,4-dimethoxy-phenyl)-1-(7-methoxy-benzo(1,3)dioxol-5-yl)-2,3-bis-methoxymethyl-butan-1-ol: from the leaves of phyllanthus amarus
4-(3,5-bis(2-chlorobenzylidene)-4-oxopiperidine-1-yl)-4-oxo-2-butenoic acid: has antineoplastic activity
4-(3,5-bis(benzyloxy)phenyl)-6-(5-chloro-2-hydroxyphenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile: a survivin modulator
4-(3,5-dibromo-2-pyridylazo)-N-ethyl-N-sulfopropylaniline: ; color reagent
4-(3,5-dihydroxybenzyl)-N-(2-methyl-4-((1-methyl-4,10-dihydropyrazolo(3,4-b)(1,5)benzodiazepin-5(1H)-yl)carbonyl)benzyl)piperazine-1-carboxamide: an anti-anxiety agent
4-(3,5-dimethoxystyryl)phenyl acetate: has antineoplastic activity
4-(3,5-dimethyl-3-aza-5-mercaptohexyl)-6,6-dimethyl-2-thiomorpholinone: used for forming neutral technetium complexes
4-(3,5-dimethylphenyl)-N-(2-methoxyphenyl)-3-methylbutanamide: a positive allosteric modulator of synaptic vesicle protein 2a
4-(3,5-dimethylphenyl)piperazine-1-carboxylic acid (2-methoxy-5,6-dimethylpyridin-3-yl)amide: has antiangiogenic and antineoplastic activities
4-(3,5-dimethylphenyl)piperazine-1-carboxylic acid(5-(1-(3-(acridine-9-yl-amino)-5-hydroxymethylphenylcarbamoyl)-ethylcarbamoyl)-6-ethyl-2-methoxypyridine-3-yl)amide: an anticancer agent
4-(3,6-bis(ethoxycarbonyl)-4,5,6,7-tetrahydrothieno(2,3-c)pyridin-2-ylamino)-4-oxobutanoic acid: enhances insulin-mediated glucose uptake in vitro and exhibits antidiabetic activity in vivo in db/db mice
4-(3-((1,1-dimethyl-3-iodopropenyl)amino)-2-hydroxypropoxy)carbazole: rn refers to (r)-isomer
4-(3-((2-(1-hydroxycyclohexyl)ethyl)-4-oxo-2-thiazolidinyl)propyl)benzoic acid: isosterically modified prostaglandin analog
4-(3-((3,5-dichloro-2-hydroxybenzylidene)amino)propyl)-4,5-dihydro-1H-pyrazol-5-one: systemic acquired resistance (sar) inducer
4-(3-((5-(2-fluoroethoxy)pyridin-2-yl)oxy)benzylidene)-N-(pyridazin-3-yl)piperidine-1-carboxamide: a pet imaging agent for brain fatty acid amide hydrolase
4-(3-(1,2-dihydro-6-methoxynaphthalen-4-yl)-n-propyl)-1-(2-methoxyphenyl)piperazine: has high affinity for 5-ht(1a), moderate affinity for dopamine d2 & low affinity for 5-ht2 receptors;
4-(3-(1,2-dihydro-8-methoxynaphthalen-4-yl)-n-propyl)-1-(2-pyridyl)piperazine: has high affinity for 5-ht(1a), moderate affinity for dopamine d2 & low affinity for 5-ht2 receptors
4-(3-(1-(2-(4-(2,4-dimethoxybenzoyl)phenoxy)acetyl)piperidin-4-yl)propyl)-N-(4-fluorophenyl)piperidine-1-carboxamide: has antineoplastic activity
4-(3-(1-adamantyl)-4-hydroxyphenyl)-3-chlorocinnamic acid: an apoptosis-inducing agent
4-(3-(1-benzotriazolyl)cyclohexyl)-1-(2-methoxyphenyl)piperazine: a 5-ht(1a) receptor antagonist
4-(3-(2,3-dihydroxypropyl)-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)-1-(spiro(bicyclo(2.2.1)heptane-2,1'-cyclopropan)-3-ylmethyl)piperidine: an opioid receptor-like 1 receptor antagonist
4-(3-(2,4-dihydroxyphenyl)-5-(2,4-dimethoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide: a cftr channel potentiator
4-(3-(2,6,6-trimethyl-1-methyl-1-cyclohexen-1-yl)-2-(propenylidene)-2-cyclohepten-1-ylidene)acetaldehyde: rn given refers to all (e)-isomer; rn from ca; rn for cpd not in chemline 5/84
4-(3-(2,6-dimethylpyridin-4-yl)phenyl)-7-methyl-8-trifluoromethyl-1,3-dihydrobenzo(b)(1,4)diazepin-2-one: an antagonist of both mglur2 and mglur3
4-(3-(2-fluorophenyl)-2,2-dioxido-2,1,3-benzothiadiazol-1(3H)-yl)-1-(methylamino)butan-2-ol: a norepinephrine reuptake inhibitor
4-(3-(2-nitro-1-imidazolyl)propylamino)-1,5-naphthyridine hydrochloride: antineoplastic
4-(3-(2-nitro-1-imidazolyl)propylamino)-2-methylquinazoline hydrochloride: antineoplastic
4-(3-(2-propyl-3-hydroxy-4-acetyl)phenoxy)propyloxyphenoxy acetic acid: a ppar-delta agonist has regulatory effects on a variety of adipokines, and these effects might explain some of their metabolic function
4-(3-(2H-1,2,3-triazol-2-yl)phenylamino)-2-(2-aminocyclohexylamino)pyrimidine-5-carboxamide: a spleen tyrosine kinase (syk) inhibitor
4-(3-(3,3-dimethyloxiran-2-yl)-1-methylpropyl)-1-methylcyclohex-2-en-1ol: male-specific aggregation pheromone of murgantia histrionica
4-(3-(3-fluoro-5-(trifluoromethyl)benzyl)-5-methyl-1H-1,2,4-triazol-1-yl)-2-methylbenzamide: selective gpr52 agonist
4-(3-(4-(1-methyl-1H-pyrazol-5-yl)phenylthio)phenyl)-tetrahydro-2H-pyran-4-carboxamide: a lipoxygenase inhibitor
4-(3-(4-(2-methoxyphenyl)piperazin-1-yl)propoxy)-4-azatricyclo(5.2.1.02,6)dec-8-ene-3,5-dione: binds 5-ht1a serotonin receptors
4-(3-(4-(2-methoxyphenyl)piperazine-1-yl)propoxy)-9H-xanthen-9-one: an adrenergic alpha1 antagonist
4-(3-(4-(3-chlorobenzoyl)piperazin-1-yl)propoxy)phenyl)(cyclopropyl)methanone: an histamine h3 receptor inverse agonist
4-(3-(4-(4-fluoro-phenyl)-3,6-dihydro-2H-pyridin-1-yl)-2-hydroxy-propoxy)-benzamide: is a voltage-independent, non-competitive antagonist of n-methyl-d-aspartate (nmda) receptors in rat cultured cortical neurones and exhibits a state-dependent mode of action
4-(3-(4-benzoylpiperazin-1-yl)-2-(benzyloxycarbonylamino)-3-oxopropyl)-3,5-dimethylphenyl 4-methylbenzenesulfonate: a p2x7 receptor antagonist
4-(3-(4-benzylpiperidin-1-yl)prop-1-ynyl)phenol: an nr1(a)/2b antagonist
4-(3-(4-cyanophenoxy)propyl)-1H-imidazole: h(3)-receptor histamine antagonist
4-(3-(4-cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorobenzyl)-2H-phthalazin-1-one: a poly(adp-ribose) polymerase-1 inhibitor
4-(3-(4-piperidin-1-ylbut-1-ynyl)benzyl)morpholine: a histamine h3 receptor antagonist
4-(3-(5'-bromo-2'-oxospiro((1,3)dioxane-2,3'-indoline)-1'-yl)propanamido)-N-hydroxybenzamide: hdac inhibitor
4-(3-(5-(1H-indol-2-yl)-2,4-dimethoxyphenyl)acryloyl)benzoic acid: a vcam-1 inhibitor
4-(3-(6-(3-benzo(1,3)dioxol-5-yl-5-thiophen-3-ylphenoxy)hexyl)-2-(2-carboxyethyl)phenoxy)butyric acid: dual blt1 and blt2 receptor antagonist
4-(3-(7-chloro-5,11-dihydrodibenz(b,e)(1,4)oxazepin-5-yl)propyl)-alpha,beta-1-piperazineethanol: rn given refers to parent cpd
4-(3-(7-methyl-1,8-naphthyridin-2-ylamino)propyl)-7-N,N-dimethylaminosulfonylbenzo-2-oxa-1,3-diazole: fluorescent ligand that binds pyrimidine bases
4-(3-(acryloyloxy)-2-hydroxypropoxy)phenyl 4-(3-(acryloyloxy)-2-hydroxypropoxy)benzoate: a liquid-crystalline resin monomer used to form low shrinkage resins
4-(3-(benzotriazol-1-yl)propyl)-1-(2-methoxyphenyl)piperazine: a putative 5-ht1a receptor antagonist
4-(3-(dimethylamino)-2-hydroxypropyl)-1,7-dimethyl-8,9-diphenyl-4-azatricyclo(5.2.1.0(2,6))dec-8-ene-3,5,10-trione: has antineoplastic activity
4-(3-(piperidin-1-yl)propoxy)-N-(3-chloro-4-fluorophenyl)-2-hydroxybenzamide: inhibits epidermal growth factor receptor
4-(3-3,4-p-menthadien-(1,8)-yl)olivetol: has vasodilating activity
4-(3-acetamidomethyl)phenyl-2-(2-(2-(2-methoxyphenyl)ethyl)guanidino)thienylthiazole: anti-helicobacter pylori agent
4-(3-acetyl-5-(acetylamino)-2-methyl-2,3-dihydro-1,3,4-thiadiazole-2-yl)phenyl benzoate: a thiadiazole derivative
4-(3-amino-4-(2,4,5-trifluorophenyl)butanoyl)-3-(2,2,2-trifluoroethyl)-1,4-diazepan-2-one: putative antidiabetic agent
4-(3-amino-4-(2,4,5-trifluorophenyl)butanoyl)-3-(tert-butoxymethyl)piperazin-2-one: a dipeptidyl peptidase iv inhibitor
4-(3-aminopropyl)pyrazole: affinity ligand for alcohol dehydrogenase purification
4-(3-aminopyrrolidin-1-yl)-6-isopropylpyrimidin-2-ylamine: a histamine h4 receptor antagonist
4-(3-benzyl-4-(5-(2-fluorophenyl)-ruan-2-ylmethylene)-5-oxo-4,5-dihydropyrazol-1-yl)benzoic acid: inhibits nf-kappab signaling
4-(3-benzyloxy-4-methoxy)phenyl-3-butenoic acid: inhibits peptidylglycine-hydroxylating monooxgenase
4-(3-bromo-8-chloro-11H-benzo(5,6)cyclohepta(1,2-b)pyridin-11-yl)-1-((4-pyridinyl)acetyl)piperidine N1-oxide: farnesyl protein transferase inhibitor
4-(3-chloro-2-fluorophenoxy)-1-((6-(1,3-thiazol-2-ylamino)pyridin to 2-yl)methyl) cyclohexanecarboxylic acid: an aurora a kinase inhibitor
4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)-6-(5-hydroxymethylfuran-2-yl)quinazoline: an egfr inhibitor with antineoplastic activity
4-(3-chloro-4-methoxyphenyl)-2-(4-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenoxy)butyl)4a,5,8,8a-tetrahydro-2H-phthalazin-1-one: a dual pde3/pde4 inhibitor
4-(3-chloro-5-(1,2-dihydroxyethyl)-2-pyridyl)-N-(5-(trifluoromethyl)-2-pyridyl)-3,6-dihydro-2H-pyridine-1-carboxamide: a trpv1 receptor antagonist
4-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(4-methoxypyridin-2-yl)piperazine-1-carbothioamide: inhibits phosphopantetheinyl transferase
4-(3-dimethylpropylamino)-1,3-dimethyl-lH-pyrazolo(3,4-b)quinoline: rn given refers to parent cpd
4-(3-fluoro-2-methylphenyl)-4,5-dihydrooxazol-2-ylamine: a partial agonist of trace amine-associated receptor 1
4-(3-fluoro-4- methoxyphenyl)-N-(4-phenoxyphenyl)-1,3-thiazol-2-amine: an aminothiazole that inhibits of microsomal prostaglandin e synthase-1
4-(3-fluoroazetidin-1-yl)-7-methyl-5-(1-methyl-5-(4-(trifluoromethyl)phenyl)-1H-pyrazol-4-yl)imidazo(5,1-f)(1,2,4)triazine: a pet radioligand for phosphodiesterase 2a
4-(3-fluoropropyl)glutamic acid: a pet radiotracer for imaging hepatocellular carcinoma
4-(3-hydroperoxy-3-methyl-1-butenyl)-9-methoxy-7H-furo(3,2-g)(1)benzopyran-7-one: ; rn given refers to compound with no isomeric designation
4-(3-hydroxybutyl)-3,3,5-trimethylcyclohex-4-ene-1,2-diol: isolated from acer truncatum
4-(3-hydroxymethyl-5-(3-hydroxypropyl)-2,3-dihydrobenzofuran-2-yl)-2-methoxyphenol: isolated from the bark of pinus sylvestris
4-(3-isopropyl-5-(6-phenyl-3-pyridyl)-4H-1,2,4-triazol-4-yl)-2,1,3-benzoxadiazole: inhibits glycine transporter 1
4-(3-methoxy-phenylsulfannyl)-7-nitro-benzofurazan-3-oxide: binds bcl-2 and induces apoptosis in leukemia cells
4-(3-methyl-2-butenyl)oxy-1-phenylacetic acid: isolated from aspergillus ochraceus
4-(3-pentylamino)-2,7-dimethyl-8-(2-methyl-4-methoxyphenyl)pyrazolo(1,5-a)pyrimidine: an hcrf(1) antagonist
4-(3-phenyl-(1,2,4)-thiadiazol-5-yl)piperazine-1-carboxylic acid phenylamide: an inhibitor of fatty acid amide hydrolase
4-(3-pyridyl)-4-oxobutyramide: metabolite of nicotine and cotinine
4-(3-thioxo-3H-1,2-dithiol-5-yl)phenyl 2-((4-(nitrooxy)butanoyl)oxy)benzoate: releases both nitric oxide and hydrogen sulfide
4-(3-trifluoromethylpyridin-2-yl)piperazine-1-carboxylic acid (5-trifluoromethylpyridin-2-yl)amide: a trpv1 vanilloid receptor antagonist
4-(3a,4,5,6,7,7a-hexahydrobenzo(d)isoxazol-3-yl)-2-(trifluoromethyl)benzonitrile: an androgen receptor modulator
4-(4',4'-dimethylcyclohexyl)-2-methylcyclohexanone: a structural and functional analog of androstenone
4-(4'-(((3,4-dihydro-3-hydroxy-2H-1,5-benzodioxepin-3-yl)methyl)thio)(1,1'-biphenyl)-4-yl)-2,4-dioxobutanoic acid: inhibitor of glycolic acid oxidase; rn &
4-(4'-(2''-methoxy-4''-hydroxy-3'',6''-dimethylbenzoyloxy)-3',5',6'-trimethyl-2'-methoxybenzoyloxy)-2-methoxy-3,6-dimethylbenzoic acid: from a soil fungus, coniochaeta sp. 10f058
4-(4'-(4''-hydroxybenzyloxy)benzyloxy)benzyl methyl ether: isolated from gastrodia elata
4-(4'-azidobenzoimidylamino)butanoic acid: competitive inhibitor of gaba uptake in rat brain synaptosome
4-(4'-bromo(1,1'-biphenyl)-4-yl)-2,4-dioxobutanoic acid: rn & structure from first source, rn not in chemline 8/83; inhibits glycolic acid oxidase;
4-(4'-chlorophenyl)-4-piperidinol: ; n-dealkylated model of haloperidol
4-(4'-hydroxy-3'-methylbut-2'-enyl)-L-tryptophan synthetase: enzymatic synthesis of above cpd from isopentenylpyrophosphate & tryptophan
4-(4'-hydroxybenzyl)phenyl glucoside: isolated from the rhizomes of gastrodia elata
4-(4'-iodobiphenyl-4-yl)-N-octyl-4-oxobutanamide: a spect tracer for imaging cox enzyme-expressing tumors
4-(4'-nitro-2'-methylsulfonylphenylazo)phenyl phosphate: colorimetric reagent; substrate of alkaline phosphatase
4-(4,10-dihydro-10-oxothieno(3,2-c)(1)-benzoxepin-8-yl)butanol: rn & ; rn not in chemline 4/84
4-(4,10-dihydro-10-oxothieno(3,2-c)(1)benzoxepin-8-yl)butyric acid: rn & ; rn not in chemline
4-(4,4,8-trimethyl-7-oxo-3-oxabicyclo(3.3.1)non-2-yl)benzoic acid methyl ester: an antileishmanial agent
4-(4,4-dimethyl-3-(4--hydroxybutyl)-5-oxo-2-thioxo-1-imidazolidinyl)-2-iodobenzonitrile: an androgen receptor ligand
4-(4,5-diphenyl-1H-imidazol-2-yl)benzoyl chloride: used to derivatize methamphetamines
4-(4,6-dichloro-(1,3,5)-triazin-2-ylamino)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid: a dnase gamma inhibitor
4-(4,6-diphenyl-1,3-dioxan-2-yl)-N,N-dimethylaniline: an androstane receptor activator
4-(4-(((1-(4-chlorobenzoyl)-1H-indol-3-yl)methylene)amino)phenyl)morpholine-3-one: has both anti-inflammatory and analgesic activities
4-(4-((1-((3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl)thio)-1-methylethyl)thio)-2,6-bis(1,1-dimethylethyl)phenoxy)butanoic acid: an antioxidant that inhibits vascular cell adhesion molecule-1 expression
4-(4-((2',3',4',6'-tetra-O-acetylgalactopyranosyl)oxymethyl)-1H-1,2,3-triazol-1-yl)benzenesulfonamide: a carbonic anhydrase inhibitor
4-(4-((2',3',4',6'-tetra-O-acetylglucopyranosyl)thiomethyl)-5-iodo-1-H-1,2,3-triazol-1-yl)benzenesulfonamide: inhibit carbonanhydrase ix
4-(4-((3-(2-amino-4-hydroxy-6-methyl-5-pyrimidinyl)propyl)amino)phenyl)-1-chloro-3-buten-2-one: anti-viral agent against h5n1 avian influenza
4-(4-((3-(hydroxycarbamoyl)-8-azaspiro(4.5)decan-3-yl)sulfonyl)phenoxy)-N-methylbenzamide: an antihemorrhagic agent
4-(4-((4-chloro-3-ethyl-1-methylpyrazol-5-yl)carbonylaminomethyl)phenoxy)benzoic acid: major metabolite of tolfenpyrad
4-(4-((4-diethylcarbamoylphenyl)(3-hydroxyphenyl)methyl)-2,5-dimethylpiperazin-1-ylmethyl)benzoic acid: ard-353 is the (2r,5s)-isomer; a cardioprotective agent
4-(4-((5,7-dimethyl-2-ethyl-3H-imidazo(4,5-b)pyridin-3-yl)methyl)phenyl)-3-(2H-tetrazol-5-yl)quinoline: an at1 angiotensin ii receptor antagonist
4-(4-((5-(4,5-dimethyl-2-nitrophenyl)-2-furanyl)methylene)-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl)benzoic acid: a potent and specific inhibitor of p300/cbp hat activity
4-(4-((glucopyranosyl)thiomethyl)-5-iodo-1-H-1,2,3-triazol-1-yl)benzenesulfonamide: inhibits carbonic anhydrase ix
4-(4-((thiiran-2-ylmethyl)sulfonyl)phenoxy)phenyl ethylcarbamate: an mmp-2 inhibitor
4-(4-(1-methylbenzimidazol-2-yl)piperazin-1-yl)sulfonylbenzenecarbohydroxamic acid: a histone deacetylase inhibitor
4-(4-(1H-tetrazol-5-yl)-1H-pyrazol-1-yl)-6-morpholino-N-(4-nitrophenyl)-1,3,5-triazin-2-amine: a phosphodiesterase-3 inhibitor with cardiotonic activity
4-(4-(2,3-dihydro-1,4-benzodioxin-6-yl)-1H-pyrazol-3-yl)benzene-1,3-diol: a cartilage repair agent
4-(4-(2,4-dichlorophenylamino)-7-methoxyquinazolin-6-yloxy)-N-hydroxybutanamide: antineoplastic
4-(4-(2,4-dioxothiazolidin-5-ylidenemethyl)-2-methoxyphenoxy)-3-trifluoromethylbenzonitrile: an estrogen-related receptor alpha ligand with antidiabetic activity
4-(4-(2-(n-butoxy)ethoxy)-5-methylthiazol-2-yl)-2-fluorobenzoic acid: an rar beta2 agonist
4-(4-(2-(phenyl-2-pyridinylamino)ethoxy)phenyl)butyric acid: a gpr120 agonist
4-(4-(2-methylpyridyl))-2-methyl-1H-imidazole: rn and ; rn not in chemline 12/85
4-(4-(3,4-dichlorophenyl)thiazolylamino)benzenesulfonamide: inhibts interaction between anthrax edema factor and calmodulin
4-(4-(3,4-diethoxyphenyl)-1oxo-4a,5,8,8a-tetrahydro-1H-phthalazin-2-yl)benzoic acid: a pde4 inhibitor
4-(4-(3,4-difluorophenyl)pyrimidin-2-yl)-N-(pyridazin-3-yl)piperazine-1-carboxamide: an inhibitor of fatty acid amide hydrolase
4-(4-(3-(-5-Fluoro-3,4-dihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-5-isopropyl-1H-pyrazol-4-ylmethyl)phenyl)-N-(2-hydroxy-1,1-bis(hydroxymethyl)ethyl)-butyramide: inhibits sodium dependent glucose transporter sglt1
4-(4-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)pyridin-2-yl)-N-(tetrahydro-2H-pyran-4-yl)benzamide: a tgf type i receptor antagonist
4-(4-(3-hydroxyphenyl)-3-(4-methylphenyl)-6-oxo-1H,4H,5H,6H-pyrrolo(3,4-c)pyrazol-5-yl)benzoic acid: a gpr55 antagonist
4-(4-(3-methoxyphenyl)cyclohexyl)-1-(2-pyridinyl)piperazine: a 5-ht(1a) receptor agonist
4-(4-(3-methylmorpholin-4-yl)-6-(1-(methylsulfonyl)cyclopropyl)pyrimidin-2-yl)-1H-indole: an antineoplastic agent that inhibits atr protein kinase
4-(4-(4,5-dibromo-1H-imidazol-1-yl)thiazol-2-yl)morpholine: an androgen receptor antagonist
4-(4-(4-chloro-phenyl)thiazol-2-ylamino)phenol: orally bioavailable sphingosine kinase inhibitor
4-(4-(4-chlorophenyl)-1,4-diazepan-1-yl)-1-(4-fluorophenyl)butan-1-one: an antipsychotic agent
4-(4-(4-chlorophenyl)-1,4-diazepan-1-yl)-1-(4-fluuorophenyl)butan-1-one: an antipsychotic agent
4-(4-(4-chlorophenyl)-4-hydroxyazepan-1-yl)-1-(4-fluorophenyl)butan-1-one: has antiparkinson activity
4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-1-(4-fluorophenyl)butyl 4-phenylbutyrate: a sigma2 receptor antagonist
4-(4-(4-chlorophenyl)-5-(1,2,3)triazol-2-ylmethyl-4H-(1,2,4)triazol-3-yl)piperidin-1-yl-(3,5-difluorophenyl)methanone: a vasopressin v(1a) receptor antagonist
4-(4-(4-dimethylaminophenyl)-5-phenyl-1H-imidazol-2-yl)benzoic acid methyl ester: binds human serum albumin
4-(4-(4-diphenylmethoxy-1-piperidyl)butyryl)dimethylphenylacetic acid: an active metabolite of ebastine
4-(4-(4-fluorophenyl)-1-(1-(1,2-oxazol-3-ylmethyl)piperidin-4-yl)-1H-imidazol-5-yl)pyrimidin-2-amine: inhibits both casein kinase 1delta and 1epsilon
4-(4-(4-fluorophenyl)thiazol-2-ylamino)-2,6-dimethylphenol: a 5-lipoxygenase inhibitor and anti-inflammatory agent
4-(4-(5,5,6,6,6-pentafluoro-1-(4-fluorobenzene-sulfonamido)hexyl)phenyl)butyric acid: a leukotriene d(4)/thromboxane a(2) dual receptor antagonist
4-(4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-quinoxalinyl)-1,3-thiazol-2-yl)benzoic acid: an rargamma agonist
4-(4-(5-(glucopyranosyloxy)-3,7,7-trimethylcyclohept-2-en-1-ylidene)-3-methylbut-2-enyl)tetrahydro-3,3a,4-trihydroxyfuro(3,4-b)furan-6(4H)-one: isolated from cydonia vulgaris
4-(4-(6-methoxy-2-benzoxazolyl)phenyl)-1,2,4-triazoline-3,5-dione: a cookson-type reagent
4-(4-(N-acetylsulfonamido)phenyl)-3-(4-methanesulfonylphenyl)-2(5H)-furanone: a cyclooxygenase-2 inhibitor
4-(4-(N-benzoylamino)anilino)-6-methoxy-7-(3-(1-morpholino)propoxy)quinazoline: inhibits aurora kinase
4-(4-(aminomethyl)-7a-methyl-1-methylideneoctahydro-1H-inden-5-yl)-3-(hydroxymethyl)-4-methylcyclohexan-1-ol: inhibits sh2-containing inositol-5'-phosphatase 1 (ship1)
4-(4-(bis(4-fluorophenyl)methyl)piperazin-1-ylbut-2-enyloxy)acetic acid: sun-1334h is the (e)-isomer,di-hcl salt; an antihistamine
4-(4-(dihexadecylamino)styryl)-N-methylquinolinium iodide: an orange red lipophilic dye
4-(4-(dimethylamino)phenyl)-1-methylpyridinium: a fluorescent substrate for the serotonin transporter
4-(4-(dimethylamino)phenyl)-6-(4-(methylsulfonyl)phenyl)-5-phenyl-3,4-dihydropyrimidin-2(1H)-one: a cox-2 inhibitor with anti-inflammatory activity
4-(4-(dimethylamino)styryl)-1-docosylpyridinium: a hemicyanine dye
4-(4-(methylsulfonyl)phenyl)-1-pentyl-3-phenoxyazetidin-2-one: has antineoplastic activity
4-(4-(toluene-4-sulfonyl)-2,3,4,5-tetrahydrobenzo(f)(1,4)oxazepin-3-ylmethyl)phenol: has antineoplastic activity
4-(4-(trifluoromethyl)phenyl)-N-(6-fluoro-1H-indazol-5-yl)-2-methyl-6-oxo-1,4,5,6-tetrahydro-3-pyridinecarboxamide: a rho kinase inhibitor
4-(4-N,N-dimethylaminophenyl)but-3-en-2-one: rn given refers to compound with no isomeric designation
4-(4-N,N-dimethylaminostyryl)-N-vinylbenzylopyridinium chloride: a fluorescent probe
4-(4-acetylpiperazin-1-yl)-2-(1H-imidazol-1-yl)aniline: a free radical scavenger with protective activity against light-induced photoreceptor degeneration
4-(4-biphenyl)-2-(4-(methylsulfonyl)phenyl)phthalazin-1(2H)-one: has anti-inflammatory activity
4-(4-bis(2-chloroethyl)amino-2-iodophenyl)butyric acid: precursor of chlorambucil & reagent for converting aniline mustard & melphalan to analogous iodo derivs
4-(4-bromoacetylphenylazoamide)phenylarsonic acid: bromoacetyl deriv of homologous hapten used in affinity labeling of anti-p-azobenzenearsonate antibodies
4-(4-bromobenzoyl)-1-(2-chloroethyl)-1-nitrosohydrazinecarboxamide: a cytostatic agent
4-(4-bromophenyl)-2,3-dihydro-N,3-bis(3,4,5-trimethoxyphenyl)-2-oxoidmi-dazole-1-carboxamide: mz3 is a potent compound against leukemia cell lines both in vitro and in vivo, and the mitochondrial pathway mediated by bcl-2 protein family and mapks might be involved in signaling mz3-induced apoptosis
4-(4-bromophenyl)-2-pyridin-3-yl-1,3-thiazole: affects plant stomatal patterning
4-(4-bromophenyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta(c)quinoline-8-sulfonamide: an alpha7 nicotinic receptor agonist
4-(4-bromophenyl)-4-hydroxypiperidine: a bromperidol metabolite
4-(4-chloro-2-methylphenoxy)-N-hydroxybutanamide: a c-flip inhibitor
4-(4-chloro-5-(3-fluoro-4-methoxyphenyl)imidazol-1-yl)benzenesulfonamide: a cox-2 inhibitor
4-(4-chlorobenzyl)-1-(7H-pyrrolo(2,3-d)pyrimidin-4-yl)piperidin-4-amine: an antineoplastic agent
4-(4-chlorophenoxy)-2-trichloromethylquinazoline: an antimalarial
4-(4-chlorophenyl)-1-(1H-imidazol-1-yl)butan-2-ol: inhibits heme oxidase
4-(4-chlorophenyl)-1-(4-(4-fluoro-phenyl))-4-hydroxybutylpyridinium: a pyridinium metabolite of haloperidol in patients with schizophrenia
4-(4-chlorophenyl)-1-(5-amino-3-methylisoxazole-4-carbonyl)thiosemicarbazide: has immunomodulatory activity
4-(4-chlorophenyl)-2-oxo-3-butenoic acid: rn given refers to unlabeled cpd without isomeric designation
4-(4-chlorophenyl)-3-methylbut-3-en-2-oxime: a trpa1 antagonist
4-(4-chlorophenyl)-4-hydroxy-alpha,alpha-diphenyl-1-piperidinepentanenitrile: a ccr1 receptor antagonist
4-(4-chlorophenyl)imidazole: inhibits cytochrome p450 2b6
4-(4-cyano-2-(2-(4-fluoronaphthalen-1-yl)propionylamino)phenyl)butyric acid: a prostaglandin e receptor ep4 subtype antagonist
4-(4-cyanophenyl)-2-(2-cyclopentylidenehydrazinyl)thiazole: a nat10 inhibitor
4-(4-cyclohexyl-2-methyloxazol-5-yl)-2-fluorobenzenesulfonamide: prostaglandin h synthase-2 inhibitor
4-(4-cyclopentylnaphthalen-1-yl)-4-oxobutanoic acid: inhibits the interaction between epha2 and ephrin-a1
4-(4-diethylaminostyryl)-N-methylpyridinium: fluorescent probe
4-(4-dihexadecylaminostyryl)-N-methylpyridium: rn refers to iodide
4-(4-dimethylaminophenyl)-1,2,4-triazoline-3,5-dione: used to derivatize 25-hydroxyvitamin d3
4-(4-dimethylaminophenylazo)benzoyl-4-aminobutanoyl-isoleucyl-histidyl-prolyl-phenylalanyl-histidyl-leucyl-valyl-isoleucyl-histidyl-threonyl-5-((2-aminoethyl)amino)naphthalene-1-sulfonic acid: used for measuring the proteolytic activity of renin
4-(4-dimethylaminostyryl)-1-methylpyridinium: fluorescent probe for living cells
4-(4-ethyl-5-fluoro-2-hydroxyphenoxy)-3-fluorobenzamide: has antibacterial activity
4-(4-ethyl-phenyl)-3-(2-methyl-3H-imidazol-4-yl)-2-quinolone-6-carbonitrile: an inhibitor of the kinase domain of macrophage colony-stimulating factor-1 receptor
4-(4-ethyl-piperazin-1-yl)-1-(2,3,4-trihydroxyphenyl)butan-1-one: metabolite of sp-04 compound; neuroprotective agent for treating alzheimer's disease; a sigma-1 receptor antagonist
4-(4-ethylamino-(4-(N-ethylamino)-4'-(dimethylamino)stilbene))-1,4,7,10-tetraazacyclotridecane-11,13-dione: a fluorescent chemosensor for detecting cupric ion
4-(4-fluoro-2,1,3-benzoxadiazol-7-ylthio)-7-mercapto-2,1,3-benzoxadiazole: a chromogenic chemosensor
4-(4-fluorobenzyl)-2-p-tolyl-1,2,4-thiadiazolidine-3,5-dione: a regulator of g protein signaling (rgs) inhibitor
4-(4-fluorobenzylcarbamoyl)-1-methyl-2-(2-(5-methyl-1,3,4-oxadiazole-2-carboxamido)propan-2-yl)-6-oxo-1,6-dihydropyrimidin-5-yl benzoate: has anti-hiv activity
4-(4-fluorophenyl)-1-(2-chloroethyl)-1-nitrosohydrazinecarboxamide: a cytostatic agent
4-(4-fluorophenyl)-1-(4-piperidinyl)-5-(4-pyridyl)-imidazole: inhibits p38 map kinase
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole: ; inhibits p38 map kinase
4-(4-fluorophenyl)-N-(3-(pyridin-2-yl)-1H-pyrazol-5-yl)piperazine-1-carboxamide: an antileishmanial agent
4-(4-fluorophenyl)-N-(4-(3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-yloxy)phenyl)phthalazin-1-amine: an aurora kinase inhibitor
4-(4-fluorophenyl)amino-5,6,7-trimethoxyquinazoline: has antineoplastic activity
4-(4-fluorophenyl)sulfonyl-5-methylthio-2-phenyloxazole: enhances autophagy in vitro and reduces diabetes and metabolic syndrome in mice
4-(4-guanidinobenzoyloxy)phenylacetic acid: rn given refers to monomethanesulfonate
4-(4-hept-1-enylphenoxy)butyric acid: potentiates alpha7 acetylcholine receptor through partial activation of camkii
4-(4-hydroxy-3,5-bis(morpholin-4-ylmethyl)phenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid diethyl ester: has both antihypertensive and antiarrhythmic activities
4-(4-hydroxy-3-methoxybenzylidene)-1-(3-nitrophenyl)-3-phenyl-1H-pyrazol-5(4H)-one: a farnesoid x receptor antagonist and anticholesteremic agent
4-(4-hydroxy-3-methoxyphenylmethyl)curcumin: has antineoplastic activity
4-(4-hydroxyphenyl)cycloheptanemethanol: a selective estrogen receptor-beta agonist
4-(4-methoxy-2-nitrophenylamino)-4-oxobutanoic acid: has antineoplastic, antileishmanial, antifungal, and antibacterial activities
4-(4-methoxy-3-(5-phenylpentoxy)phenyl)-2-methylbenzoic acid: inhibits phosphodiesterase type iv
4-(4-methoxyphenyl)-5-(3,4,5-trimethoxyphenyl)-1H-pyrazol-3-amine: a tubulin polymerization inhibitor and potential antineoplastic agent
4-(4-methoxyphenyl)pyrido(4',3'-4,5)thieno(2,3-b)pyridine-2-carboxamide: has estrogenic activity
4-(4-methylbenzyl)-4'-(guanidinomethylbenzoyloxy) biphenyl-4-carboxylate hydrochloride: anti-helicobacter pylori
4-(4-methylphenyl)-2-methylthiomethyl-4-oxobutanoic acid: a metabolite of esonarimod
4-(4-methylpiperazin-1-yl)-6-phenyl-2-vinylpyrimidine: an h4 receptor partial agonist
4-(4-methyoxycinnamoyl)mussatioside: phenylpropanoid from liana mussatia
4-(4-morpholinyl)-2,3-pentamethylenequinoline: rn given refers to parent cpd
4-(4-nitrobenzyl)pyridine: reagent for determination of organophosphorus pesticides spectrophotometrically
4-(4-nitrophenyl)-1,2,4-triazoline-3,5-dione: derivatization reagent for 25-hydroxyvitamin d3
4-(4-phenoxyphenylsulfonyl)butane-1,2-dithiol: inhibits matrix metalloproteinase-2
4-(4H-1,2,4-benzothiadiazine-3-yl)-2,6-bis(dimethylethyl)phenol-S,S-dioxide: a bis(1,1-dimethylethyl)phenol derivative
4-(4H-1,2,4-triazol-4-ylamino)benzonitrile: aromatase inhibitor
4-(5,6-dihydro-5,5-dimethyl-8-(quinolin-3-yl)naphthalen-2-carboxamido)benzoic acid: an raralpha antagonist
4-(5,6-dimethoxy-2-phthalimidinyl)phenylsulfonyl chloride: a fluorescent labelling reagent
4-(5,6-dimethyl-2-benzofuranyl)piperidine: selective inhibitor of serotonin uptake in rat brain; nm refers to hcl; rn given refers to parent cpd
4-(5-((1-(3-chlorobenzyl)-2-oxopyrrolidin-3-ylamino)methyl)imidazol-1-ylmethyl)benzonitrile: a farnesyltransferase inhibitor
4-(5-((5-(4-bromophenyl)-2-furyl)methylene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl)butanoic acid: inhibits apoptosis signal-regulating kinase 1 (ask1)
4-(5-(1-methyl-1H-pyrrol-2-yl)-1,3,4-oxadiazol-2-yl)-1,4-diazabicyclo(3.2.2)nonane: an alpha7 nicotinic acetylcholine receptor agonist
4-(5-(1-methylpiperidin-4-yloxy)-1H-benzo(d)imidazol-1-yl)-2-(1-(2-(trifluoromethyl)phenyl)ethoxy)benzamide: a nek2 inhibitor
4-(5-(2,5-dimethylphenyl)-3-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide: an antineoplastic agent
4-(5-(3-hydroxycyclohexylimino)-4-methyl-4,5-dihydro-(1,3,4)thiadiazol-2-yl)benzamide: inhibits phosphodiesterase 7
4-(5-(3-trifluoromethylphenyl)pyridin-2-yl)ethenyl-3-methyldecahydronaphtho(2,3-c)furan-1(3H)-one: an antithrombotic agent
4-(5-(4-aminophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide: a celecoxib derivative that induces apoptosis in synovial fibroblasts; inhibits cyclooxygenase-2
4-(5-(4-chlorophenyl)-2-methyl-3-propionyl-1H-pyrrol-1-yl)benzenesulfonamide: positive modulator of alpha7 nicotinic acetylcholine receptor
4-(5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide: sc58236 = sc236 re email from "harris, ray" <ray.harris@vanderbilt.edu> 08/28/03 03:24pm
4-(5-(4-fluorophenyl)-2-methylsulfanyl-1H-imidazol-4-yl)pyridine: inhibits cytokine release
4-(5-(4-fluorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide: a long-acting cox-2 inhibitor
4-(5-(4-hydroxy-3-methoxyphenyl)-3-oxopenta-1,4-dienyl)-2-methoxyphenol: has antineoplastic activity
4-(5-(5,6,7,8-tetrahydro-5,5,8,8--tetramethylnaphthalen-2-yl)isoxazol-3-yl)benzoic acid: promotes apoptosis
4-(5-(7-fluoro-4-(trifluoromethyl)benzo(b)furan-2-yl)-1H-2-pyrrolyl)benzoic acid: a subtype-selective retinoid, on lupus-like nephritis in female (nzbxnzw)f1 mice
4-(5-(benzoylamino)thien-2-yl)-2,4-dioxobutanoic acid: an hiv-1 ribonuclease h inhibitor
4-(5-(naphthalen-1-ylmethyl)-1,3,4-thiadiazol-2-yl)benzene-1,3-diol: has antineoplastic activity
4-(5-acetyloxy-8,8-dimethyl-6-(3-methylbut-2-en-1-yl)-4-oxo-4,8-dihydropyrano(2,3-f)chromen-3-yl)-1,2-phenylene diacetate: an mtor inhibitor
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide: a tgf-beta type i receptor kinase activity inhibitor
4-(5-chloro-2,3-dihydrobenzo(d)thiazol-2-yl)-2,6-dimethoxyphenol: a tyrosinase inhibitor
4-(5-chloro-2-hydroxybenzylideneamino)-N-(thiazol-2-yl)benzenesulfonamide: has antibacterial activity
4-(5-chloro-2-hydroxyphenyl)-3-(2-hydroxyethyl)-6-(trifluoromethyl)-quinolin-2(1H)-one: a large conductance calcium-activated potassium channel opener
4-(5-chloro-2-hydroxyphenyl)-5-(3,5-bis(trifluoromethyl)phenyl)-2,4-dihydro-3H-1,2,4-triazol-3-one: a maxi-k channel opener
4-(5-chloro-2-oxo-3(2H)-benzothiazolyl)acetyl-1-piperazinesulfonic acid: metabolite of tiaramide
4-(5-chloro-6-(2,5-difluorophenoxy)-3-pyridinyl)-2-fluoro-5-methoxy-N-(methylsulfonyl)benzamide: an nav1.7 channel inhibitor
4-(5-dimethylaminonaphthalene-1-sulfonamido)-3-(4-iodophenyl)butanoic acid: a molecular probe for imaging apoptosis
4-(5-hydroxy-3-methyl-1H-indol-2-yl)benzene-1,2-diol: a pregnane x receptor antagonist
4-(5-hydroxybenzofuran-2-yl)benzene-1,2-diol: has antineoplastic activity
4-(5-methyloxazolo(4,5-b)pyridin-2-yl)-1,4-diazabicyclo(3.2.2)nonane: an alpha7 nicotinic acetylcholine receptor agonist
4-(5-naphthyl-3- (trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide: inhibits cell viability and induces apoptosis in human colon cancer sw-1116 cells
4-(5-nitrobenzofuran-2-yl)benzene-1,2-diol: has antineoplastic activity
4-(5-nitroindolin-1-yl)phenyl mannopyranoside: an antibacterial agent that inhibits fimh protein
4-(5-oxotetrahydrofuran-3-yl)benzaldehyde: from sarcodontia crocea
4-(5-pentadecyl-1,3,4-oxadiazol-2-yl)pyridine: has antitubercular activity
4-(5-thioxo-5H-1,2-dithiol-3-yl)-phenyl 2-(4-isobutyphenyl)propanoate: a hydrogen sulfide-releasing nsaid with antineoplastic activity
4-(5-thioxo-5H-1,2-dithiol-3-yl)-phenyl 2-acetoxybenzoate: a hydrogen sulfide-releasing nsaid with antineoplastic activity
4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine: inhibits l-pgds
4-(6''-chloro-4'-(3-chloro-2-fluorophenyl)-2''-oxodispiro(cyclohexane-1,2'-pyrrolidine-3',3''-indoline)-5'-carboxamido)benzoic acid: an mdm2 inhibitor
4-(6,7-dichloro-4H-1,2,4-benzothiadiazine-3-yl)-2,6-bis(1,1-dimethylethyl)phenol-S,S-dioxide: a bis(1,1-dimethylethyl)phenol derivative
4-(6,7-dihydro-5H-indeno(5,6-d)thiazol-2-yl)benzene-1,3-diol: structure in first soruce
4-(6,7-dimethoxy-9H-1,3,9-triazafluoren-4-yl)piperazine-1-carbothioic acid (4-(pyrimidin-2-ylsulfamoyl)phenyl)amide: an aurora kinase inhibitor
4-(6-(acetamidomethyl)pyridin-2-yl)-2-guanidinothiazole: has potent inhibitory activities against gastric lesions caused by nsaid in addition to strong antisecretory activity
4-(6-(cyclobutylamino)imidazo(1,2-b)pyridazin-3-yl)-2-fluoro-N-((4-fluoropyrrolidin-2-yl)methyl)benzamide: an ikkbeta inhibitor with anti-arthritic activity
4-(6-(dansylamino)hexylamino)-7-methyl-2-phenyl-1,8-naphthyridine: a fluorescent probe for studying a1-adenosine receptors
4-(6-acetyl-3-(3-(4-acetyl-3-hydroxy-2-propylphenylthio)propoxy)-2-propylphenoxy)butyric acid: an nsaid
4-(6-amino-9-methyl-8-(2H-1,2,3-triazol-2-yl)-9H-purin-2-yl)-2-methylbutan-2-ol: an adenosine a2a receptor antagonist
4-(6-amino-9H-purin-9-yl)-7-(hydroxymethyl)spiro(2.4)heptane-5,6-diol: an antiviral against hepatitis c virus
4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline: a gpr30 (gper) antagonist with neuroprotective activity
4-(6-bromo-2-benzothiazolylazo)pyrogallol: an acid-base indicator used for determination of the presence of cu(ii) and pd(ii)
4-(6-cyclohexylhex-3-enyl)imidazole: gt-2228 is the (trans)-isomer
4-(6-cyclohexylmethoxy-9H-purin-2-ylamino)-N,N-diethylbenzamide: a cyclin-dependent kinase inhibitor
4-(6-ethynyl-9H-purin-2-ylamino)benzenesulfonamide: protein kinase inhibitor
4-(6-formyl-3-azidophenoxy)butyrimidate: a protein cross-linking reagent
4-(6-hydroxy-7-tricyclo(3.3.1.13,7)dec-1-yl-2-naphthalenyl)benzoic acid: an agonist of retinoic acid receptor gamma
4-(6-methoxy-2-naphthyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)-1H-imidazole: a tie2 kinase inhibitor with antineoplastic activity
4-(6-methoxy-2-naphthyl)butan-2-ol: a nabumetone metabolite
4-(6-methoxynaphthalen-2-yl)-4-oxo-2-butenoic acid: ; rn given refers to (e)-isomer
4-(7-((3-amino-1-pyrrolidinyl)carbonyl)-1-ethyl-1H-imidazo(4,5-c)pyridin-2-yl)-1,2,5-oxadiazol-3-amine: sb-772077-b is the (3s)-isomer; an nsaid with vasodilator activity that inhibits rho kinases
4-(7-((dimethylamino)methyl)-2-(4-fluorophenyl)imidazo(1,2-a)pyridin-3-yl)pyrimidin-2-amine: an anticoccidial agent that inhibits cgmp-dependent protein kinase
4-(7-(2-(4-chlorophenoxy)ethyl)-6-hydroxy-2-(methylamino)-7H-purin-8-yl)phenylphosphonic acid: an eif4e cap binding antagonist
4-(7-acetoxy-5-(3-methoxy-3-oxoprop-1-enyl)-3-(methoxycarbonyl)-2,3-(dihydrobenzofuran-2-yl)-1,2-phenylene diacetate: has anti-angiogenic activity
4-(7-hydroxy-1-(hydroxymethyl)-2,5-dioxabicyclo(2.2.1)heptan-3-yl)-3-oxo-3,4-dihydropyrazine-2-carboxamide: an antiviral agent against influenza a virus
4-(7-methoxy-2-oxo-2H-benzopyran-4-ylmethoxy)benzoyl chloride: fluorescence reagent
4-(8-((2-cyclopropyl-5-ethoxy-4-methylphenyl)methyl)-2-oxo-1,3,8-triazaspiro(4.5)decan-3-yl)benzoic acid: a somatostatin receptor 5 antagonist
4-(8-(3-fluorophenyl)-1,7-naphthyridin-6-yl)cyclohexanecarboxylic acid: a phosphodiesterase 4 inhibitor
4-(8-(3-nitrophenyl)-(1,7)naphthyridin-6-yl)benzoic acid: a phosphodiesterase type 4d inhibitor
4-(8-chloro-3,5-dibromo-11H-benzo(5,6)-cyclohepta(1,2-b)pyridin-11-yl)-1-((4-pyridinyl)acetyl)piperidine N1-oxide: farnesyl protein transferase inhibitor
4-(9-(tetrahydrofuran-3-yl)-8-(2,4,6-trifluorophenylamino)-9H-purin-2-ylamino)cyclohexanol: a c-jun amino-terminal kinase inhibitor
4-(9-acridinylamino)-N-(lysylglycyl)aniline: rn from toxlit
4-(9-ethyl-9aH-carbazol-3-yl)amino)pent-3-en-2-one: has antineoplastic activity
4-(E)-((p-tolylimino)-methylbenzene-1,2-diol): resveratrol analog, differentially regulates estrogen receptors alpha and beta in breast cancer cells
4-(N,N,N-trimethylamino)-2,2,6,6-tetramethylpiperidine-1-oxyl: rn given refers to parent cpd; ; d-cat1 is a perdeuterated compound
4-(N,N-dimethyl-N-nonyl)ammonium-2,2,6,6-tetramethylpiperidine-1-oxyl: cationic amphipatic spin probe
4-(N,N-dimethylamino)cinnamaldoxime: rn & ; rn given refers to cpd without isomeric designation; rn not in chemline 6/84
4-(N,N-dimethylaminoazobenzene)-4'-isothiocyanate: chromophoric reagent for protein sequence analysis
4-(N,N-dimethylaminosulfonyl)-7-(2-chloroformylpyrrolidin-1-yl)-2,1,3-benzoxadiazole: r(+)- & s(-)-dbd-pro-cocl are enantiomers
4-(N,N-dimethylaminosulfonyl)-7-(3-aminopyrrolidin-1-yl)-2,1,3-benzoxadiazole: a fluorescent tagging reagent
4-(N,N-dimethylaminosulfonyl)-7-hydrazino-2,1,3-benzoxadiazole: used for the determination of medroxyprogesterone acetate in serum
4-(N,N-dipropylamino)benzaldehyde: a potent, reversible inhibitor of mouse and human class i aldehyde dehydrogenase
4-(N-(1-(2-(4-cyanophenyl)ethyl)-4-hydroxypiperidin-4-ylmethyl)-N-methylamino)benzoic acid: an analgesic
4-(N-(2-(uracil-6-ylmethyliminooxy)ethyloxy)iminomethyl)benzoic acid: inhibits ung2
4-(N-(2-hydroxy-2-methylpropyl)-ethanolamino)-2,7-bis(2,6-dimethylmorpholino)-6-(4-azidophenyl)pteridine: photoactive form of bibw22 bs
4-(N-(4'-bis(2''-iodoethyl)aminophenyl)-N-methylcarbamoyloxymethyl)phenylcarbamoylglutamic acid: a self-immolative nitrogen mustard prodrug
4-(N-(4-chlorophenyl)carbamoyloxy)-4-pent-2-ammonium iodide: muscarinic receptor m1 agonist
4-(N-(4-cyclohexylbenzyl)-2-(N,2,4,6-tetramethylphenylsulfonamido)acetamido)-2-hydroxybenzoic acid: a stat5-sh2 inhibitor with antileukemia activity
4-(N-(6-(3,5-bis(decyloxy)phenoxy)hexyl)-N-(4-carboxyphenyl)amino)benzoic acid: a pan-selectin inhibitor
4-(N-(iodoacetoxy)ethyl-N-methyl)amino-7-nitrobenz-2-oxa-1,3-diazole: fluorescent probe
4-(N-1-dimethylaminonaphthalene-5-sulfonylamino)phenyl isothiocyanate: used for micro-sequencing polypeptides
4-(N-2-chloroethyl-N-methylamino)benzaldehde octauridylate: octauridylate with alkylating group attached to 3'-end; 4-(n-2-chloroethyl-n-methylamino)benzaldehyde acetal derivative of octauridylate
4-(N-2-hydroxyethyl-N-ethylamino)-4'-(dimethyl amino)stilbene: a fluorescent dye
4-(N-maleimido)benzyltrimethylammonium: affinity-alkylating agent; rn given refers to parent cpd
4-(N-methyl-N-(4-(trifluoromethyl)phenyl)sulfamoyl) benzoic acid: a casein kinase 1alpha (ck1alpha) activator with antineoplastic properties
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone: structure; from tobacco smoke
4-(N-methyl-N-nitroso)aminoantipyrine: formed by reaction of sulpyrine with nitrite
4-(N-methyl-phalimidyl-3)-3-cyano-4-methyl-pyridone-2: cyanopyridone compound with antitumor activity
4-(N-methylamino)-4'-(2-(2-(2-fluoroethoxy)ethoxy)ethoxy)stilbene: a pet tracer for imaging amyloid beta
4-(O-methyl(orthocyanophenyl-1,2,3-triazol-4yl))podophyllotoxin: has antineoplastic activity
4-(O-nitrofurfuryl N-methyl-N-(4-chlorobutyl) phosphono(difluoromethyl))phenylacetyl-aspartyl-4-(O-nitrofurfuryl N-methyl-N-(4-chlorobutyl) phosphono(difluoromethyl))-N-(9-fluorenylmethoxycarbonyl)-phenylalanine amide: a ptp1b inhibitor prodrug
4-(acetoxymethylnitrosamino)-1-(3-pyridyl)-1-butanone: ; a pyridyloxobutylating agent used for altering dna
4-(acetylamino)-3-aminobenzoic acid: an aromatic inhibitor of influenza virus neuraminidase
4-(acetylamino)-3-hydroxy-5-aminobenzoic acid: an aromatic inhibitor of influenza virus neuraminidase
4-(acetylamino)benzoic acid-1-(dimethylamino)-2-propanol: constituent of isoprinosine
4-(acetylamino)benzylphosphonate: non-hydrolyzable substrate analog for acid phosphatase
4-(alpha-(2,5-dimethyl-4-(3-fluorobenzyl)-1-piperazinyl)benzyl)-N,N-diethylbenzamide: dpi-221 is the ((alpha-s),(2s,5r))-isomer
4-(alpha-(4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl)-N,N-diethylbenzamide: a highly-selective, nonpeptide delta opioid receptor agonist
4-(alpha-hydroxymalonyl)phenylalanine: a phosphotyrosyl mimetic
4-(aminocarbonyl)-1-(3-(4-((E)-(hydroxyimino)methyl)pyridinium-1-yl)propyl)pyridinium dibromide: a cholinesterase reactivator
4-(aminomethyl)-6-(1,1-dimethylethyl)-2-iodo-3-pyridinol: rn given refers to parent cpd
4-(aminomethyl)bicyclo(2.2.2)octane-1-carboxylic acid: rn given refers to parent cpd
4-(azidoanilido)uridine 5'-triphosphate: a membrane-topological photoaffinity probe for uridine diphosphate-sugar binding proteins
4-(benzo(b)thiophen-2-yl)-3-bromo-5-hydroxydihydrofuran-2(3H)-one: inhibits microsomal pge synthase-1 (mpges-1)
4-(benzo(d)isothiazol-3-yl)-N-(4-chlorophenyl)piperazine-1-carboxamide: an inhibitor of dna gyrase b
4-(benzo(g)quinazolin-4-ylamino)-N-(1-phenyl-1H-pyrazol-5-yl)benzenesulfonamide: has antineoplastic activity
4-(benzo(g)quinazolin-4-ylamino)benzenesulfonamide: has antineoplastic activity
4-(benzothiazol-2-yl)-4-hydroxy-2,5-cyclohexadien-1-one: an antineoplastic agent
4-(benzoylamino)-2-hydroxybenzoic acid: bepask is calcium salt
4-(benzylamino)-2-((2-(3-chloro-4-hydroxyphenyl)ethyl)amino)pyrimidine-5-carboxamide: a stat6 inhibitor and anti-asthamtic agent
4-(benzyloxy)-1-(4-(2-pyrrolidin-1-ylethoxy)phenyl)pyridin-2(3H)-one: an mch1 receptor antagonist
4-(benzyloxy)-2,6-diamino-5-nitropyrimidine: a pyrimidine derivative that inhibit human o(6)-alkylguanine-dna alkyltransferase (agat)
4-(beta-D-glucopyranosyl-1-4-alpha-L-rhamnopyranosyloxy)benzyl thiocarboxamide: antimicrobial from moringa oleifera seed extract
4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase: catalyzes reaction of 4-aminobenzoate and 5-phospho-alpha-d-ribosyl-1-pyrophosphate to yield carbon dioxide, pyrophosphate, and beta-rfa-p
4-(beta-amidinoethenyl)phenyl-4-guanidinobenzoate dimethanesulfonate: inhibitor of trypsin, plasmin, pancreatic & plasma kallikrein & thrombin; strongly inhibits esterolytic activities of c1r & c1 esterase complement-mediated hemolysis
4-(beta-aminoethyl)pyrazole: histamine analog; can induce cross-tolerance to histamine; rn given refers to di-hcl; rn for parent cpd not in chemline 8/11/83
4-(beta-erythrofuranosyl)imidazoline-2-thione: inhibits cell proliferation
4-(bis((3,5-dimethyl-1H-pyrazole-1-yl)methyl)amino)butane-1-ol: cytotoxic
4-(bis(2-((methylsulfonyl)oxy)ethyl)amino)-2-methylbenzoic acid: has antineoplastic activity