NLK-NML/MeSH-CZ-2025-notes huggingface dataset:
vibsanol C: has antineoplastic activity; isolated from viburnum odoratissimum
vibsanol F: has antibacterial activity; isolated from viburnum odoratissimum
vibsanol G: has antineoplastic activity; isolated from viburnum odoratissimum
vicedrin: contains phenacetin, ephedrine, chinin, and ascorbic acid
vicenin: isolated from the leaves of the indian plant ocimum sanctum were tested for their radioprotective effect in mice
vicenistatin: a macrocyclic lactam from streptomyces sp. hc34
vicilin protein, plant: reserve proteins from cotyledons of leguminous seeds; a 7s globulin
vicilin-like protein, plant: putative sucrose-binding protein; amino acid ; genbank z50791
vicinal diaminobenzoacridine: a fluorescent probe for the determination of trace amounts of nitric oxide radical in biological sample
vicrostatin: a synthetic peptide consisting of contortrostatin with a c-terminal graft; has antiangiogenic and pro-apoptotic activities
vidisic: liquid gel polymerized from acrylic acid; used in treatment of dry eyes
vieillardixanthone: antioxidant xanthone from garcinia vieillardii
viequeamide A: a cytotoxic cpd from a marine button cyanobacterium
vig-2 protein, Oncorhynchus mykiss: a new interferon-responsive gene in rainbow trout; amino acid
vignain: from seeds of vigna acontifolia; can be assayed with benzyloxycarbonyl-phe-arg-7-(4-methylcoumarylamide) as substrate; has properties of a cysteine endopeptidase of the papain family, with the exception of a very low reactivity with iodoacetate
vigno 5 cyclotide, Viola ignobilis: has antineoplastic activity
viguiepenol: from viguiera pinnatilobata; rn given refers to (2r-(2alpha,4aalpha,7alpha,8abeta,10abeta))-isomer; rn for cpd without isomeric designation not avail 3/92
vih protein, Drosophila: a member of the e2-c family; required for proteolysis of cyclin b; refseq nm_140325
villikinin: released from duodenal mucosa & carried by blood stream to villi where it stimulates motility; mw approx 1200
villin: major protein of microvillus cytoskeleton which binds both g & f actin; 95 kda cytoskeletal component of intestinal brush borders; also binds calcium; genbank u10070 (quail protein)
villosin, Hedychium villosum: ; do not confuse with villosins from other species
viltolarsen: antisense oliogonucleotide that targets exon 53 in the dystrophin gene
vimar protein, Drosophila: homologous to smg guanine dissociation stimulator; contains 15 tandem armadillo repeats; genbank af034421
vimentin kinase: 37 kda protein from bhk cells; phosphorylates vimentin at thr-457 and ser-458 in the c-terminal non-alpha-helical domain
viminol: proposed as antitussive or analgesic; occurs as six stereoisomer with differing action; minor descriptor (75-86); on-line & index medicus search ethanolamines (75-86); rn given refers to parent cpd without isomeric designation
vina-ginsenoside R2: has anti-inflammatory activity; isolated from panax vietnamensis
vincadifformine: rn given for (5alpha,12beta,19alpha)-isomer
vinckepain 2, Plasmodium falciparum: genbank ay063763 and af063764
vinconate: synthetic hexa-hydrocanthane alkaloid; rn given refers to (+ -)-isomer; rn for cpd without isomeric designation not avai lable 8/89
vinculin-activating peptide, Shigella flexneri: a c-terminal peptide of ipaa protein that sensitizes melanoma to chemotherapy
vindolicine: catharanthus roseus alkaloid; rn from 10th ci chem subs index for (2beta,3beta,4beta,5alpha,12beta,19alpha)-(2'beta,3'beta,4'beta,5'alpha,12'beta,19'alpha)-isomer
vineatrol: a grape-derived polyphenolic fraction with protective effect against kainic acid induced seizures, oxidative stress and on the expression of heat shock proteins in rats
viniferone A: antioxidant that prevents dna oxidative damage; isolated from grape seeds
viniphenol A: from vitis vinifera stalks, has protective effects against amyloid-β-induced toxicity in pc12 cells
vinorine: was isolated from hybrid cell suspension cultures of rauvolfia serpentina and rhazya stricta
vinpocetine: whole issue of arzneim forsch (23 articles) discuss this drug; arzneim forsch 26(10a);1976; rn given refers to parent cpd with unspecified isomeric designation
vintene: soln of 17 essential l-amino acids, l-aspartic, acetic, citric, & malic acids for parenteral nutriution
vintoperol: ; no information given that it is a vinca alkaloid; rn refers to (3alpha, 16alpha)-isomer; rn for compound without isomeric designation not available 12/90
vinyl ether: major descriptor (65-85); on-line search vinyl compounds (66-85); index medicus search vinyl ether (65-85)
vinylglycolic acid: potent, irreversible inactivator of vectorial phosphorylation
vinylite resin HV 19: used for making corrosion casts of arteries for evaluation of results of myocardial revascularization
vinyloxyethylmethacrylate: mf: c8-h12-o3
vinyloxypropionitrile: used to introduce 1-(2-cyanoethoxy)ethyl protecting groups
vinyltoluene: monomer for the manufacture of plastics & resins; considered as non-toxic substitute for styrene
vinyltriethoxysilane: aqueous adhesive for affixing sections to glass slides when hydrolyzed
vinzolidine: orally active, semisynthetic vinca alkaloid; rn refers to (3r-(3r*,5s*,7r*,9s*)-isomer
vioC protein, Chromobacterium violaceum: a non-heme iron, alpha-ketoglutarate-dependent oxygenase that catalyzes the formation of 3s-hydroxy-l-arginine during viomycin biosynthesis
viola yedoensis compound: consists of viola yedoensis makino, herb, sophora flavescens aiton, root, and dictamnus dasycarpus turcz, root and rhizome
violacein: produced by bb-78 strain of chromobacterium violaceum; involved with quorum sensing
violamycin BI: rn given refers to cpd with unknown mf; see also violamycins
violamycins: red pigment antibiotic mixture of violamycins a & b; aminoglycosides of rhodosamine & rhodomycinone produced by streptomyces violaceus imet ja 6844; see also violamycin bi
violaxanthin de-epoxidase: requires ascorbate, mechanism presumably reduction, then dehydration to form zeaxanthin
violdelphin: the anthocyanin responsible for purplish blue flower color of aconitum chinense
violerythrin: rn & n1 taken from ca 9th c.i.; not in chemline 8/83
viomellein: metabolite of penicillium viridicatum causing hepatic lesions in mice
viomycin kinase: vph from streptomyces vinaceus is involved in viomycin resistance; acts also on capreomycins; a serine residue in the peptide antibiotics acts as phosphate-acceptor
vip3LB protein, Bacillus thuringiensis: vegetative insecticidal protein of bacillus thuringiensis expressed in photorhabdus temperata; shows oral toxicity against the lepidoptera ephestia kuehniella and spodoptera littoralis
vipegitide: a synthetic platelet aggregation inhibitor that is a partial alpha2beta1 integrin antagonist
viper venoid: formalin-treated viper venom for use in prophylactic immunization
vipoxin: small basic protein from russell's viper venom with high affinity for biogenic amine receptors; found in the venom of the bulgarian viper (vipera ammodytes ammodytes)
viquidil: vasodilator agent; minor descriptor (75-86); on line & index medicus search quinolines (75-86); rn given refers to ((3r-cis)-isomer)
vir protein, Drosophila: required for expression of sex-lethal, a sex-determining gene; isolated from drosophila melanogaster; genbank af281363
virE1 protein, Agrobacterium tumefaciens: mw appx 7,000; hydrophilic protein encoded by vire operon of agrobacterium tumefaciens ti plasmid; nucleotide sequence 388 to 583 of vire operon for vire1 protein given in first source
virE2 protein, Agrobacterium: mw appx 60,500; protein encoded by vire operon of agrobacterium tumefaciens ti plasmid; nucleotide sequence 590 to 2190 of vire operon for vire2 protein given in first source; a member of the t-complex transport apparatus
virG protein, Shigella flexneri: amino acid sequence given in first source; mw 130 kda; from the plasmid-coded virulence gene of shigella flexneri; also from yersinia enterocolitica; genbank u21297 (yersinia)
virR protein, Rhodococcus equi: a lysr-type transcriptional regulator from the intracellular pathogen rhodococcus equi
viral FLIP protein, Human herpesvirus 8: has two death effector domains; has been sequenced
viral FLIP protein, Molluscum contagiosum virus: plays an essential role in the regulation of death receptor signaling; databank pdb/2f1s
viral IAP associated factor, human: an iap (inhibitor of apoptosis protein)-binding protein from a human b cell; amino acid sequence known
viral chemokine CXC-1, Cytomegalovirus: a potent alpha chemokine encoded by cytomegalovirus; 117 amino acid residue glycoprotein; amino acid
viral coat protein, Cowpea aphid-borne mosaic virus: 279 residue potyviral coat protein mw 31722; amino acid sequence given in first source
viral enhancing factor, Trichoplusia ni granulosa virus: from trichoplusia ni granulosa virus; mw 104 kda; amino acid sequence given in first source
viral protein 1, rhinovirus: a single point mutation of valine 188 to leucine in vp1 results in viral resistance to win cpds; has been sequenced
viral protein 1054, baculovirus: acmnpv - autographa californica nuclear polyhedrosis virus; amino acid sequence given in first source
viral protein 60, rabbit hemorrhagic disease virus: amino acid sequence given in first source; genbank z24757
viral protein p6: activates initiation of bacteriophage psi29 dna replication; protein p6 forms a nucleoprotein complex at the viral replication origins; contains 103 amino acids; amino acid sequence has been determined
viral superantigen 23, Mouse mammary tumor virus: a mouse mammary tumor virus (mtv), virus superantigen (vsag) specific for t cells bearing mouse vbeta7; amino acid sequence given in first source
virantmycin: has potent antifungal activity & potent inhibitory activity against dna & rna viruses; from streptomyces nitrosporeus no. am-2722; structure in 2nd source
virescenoside O: diterpene glycoside from a marine strain of acremonium striatisporum kmm 4401 associated with the holothurian eupentacta fraudatrix
virescenoside P: diterpene glycoside from a marine strain of acremonium striatisporum kmm 4401 associated with the holothurian eupentacta fraudatrix
virescenoside Q: diterpene glycoside from a marine strain of acremonium striatisporum kmm 4401 associated with the holothurian eupentacta fraudatrix
virgaricin B: produced by a fungus, virgaria boninensis fki-4958.
virgaureasaponin 1: a cytotoxic triterpenoid glycoside from root of salidago virgaurea
virgineone: a glycosylated antifungal tetramic acid from saprotrophic lachnum virgineum
virginiamycin butanolide receptor, Streptomyces: from streptomyces virginiae
virginiamycin factor S1: a component of virginiamycin; was ep to virginiamycin 1992-2001
viridamide A: lipodepsipeptide with antiprotozoal activity from the marine cyanobacterium oscillatoria nigro-viridis
viridamide B: lipodepsipeptide with antiprotozoal activity from the marine cyanobacterium oscillatoria nigro-viridis
viridaphin A(1) glucoside: from the green aphid megoura crassicauda
viridicatumtoxin: isolated from cultures of penicillium viridicatum; rn given refers to 2'alpha,7'beta,11'abeta,12'beta-(-) isomer
viridicatumtoxin B: an anti-mrsa agent isolated from penicillium
viridicin: synthesized by gram-positive bacterium aerococcus viridans; inhibits both gram-negative and gram-positive bacteria
viridifloric acid: rn given refers to (r-(r*,r*))-isomer
viridiflorol: a strong feeding deterrent for the melaleuca weevil that retards larval development
viridin: bacteriocins of alpha-hemolytic streptococcal isolates; rn given refers to (1s-(1alpha,2alpha,11balpha))-isomer
viridiofungin A: inhibits serine palmitoyltransferase; isolated from trichoderma viride
viridiofungin B: inhibits serine palmitoyltransferase; isolated from trichoderma viride
viridiofungin C: inhibits serine palmitoyltransferase; isolated from trichoderma viride
viriditoxin, rattlesnake: tissue damaging high mw protein from prairie rattlesnake (crotalus viridis viridis) venom; do not confuse with the mycotoxin viriditoxin
virion host shutoff protein, Simplexvirus: causes host mrna destabilization in herpes simplex virus; a product of ul41 gene; see also separate records for hsv-1 ul41 and hsv-2 ul41; partial amino acid sequence given in first source
virion protein mu, adenovirus: 19-amino acid dna-binding peptide derived form the l2-79r precursor by two cleavages that are mediated by the virus-encoded endoproteinase; amino acid sequence given in first source
virion protein, Calopogonium yellow vein virus: a tymovirus protein isolated from malaysian crop (calopogonium mucunoides); amino acid ; genbank u91413
virion protein, belladonna mottle tymovirus: nucleotide sequence given in first source
virion protein, erysimium latent tymovirus: amino acid sequence given in first source
virodhamine: arachidonic acid and ethanolamine joined by an ester linkage, like anandamide with oxygen and nitrogen reversed; an endocannabinoid from rat
viroidin: virotoxin from amanita virosa; rn given refers to (l)-isomer; see also related record for virotoxins; carbon 4 of 4,5-dihydroxyleucine is 2s,4s in alloviroidin
viroisin: virotoxin from amanita virosa; rn given refers to (3r-trans)-isomer; see also related record for virotoxins
viron: a complex group of biologics botanicals; shown to be effective in the management of adult patients with hiv-1 and hiv-2; no further information available 4/97
viroplasmin protein, Cauliflower mosaic virus: amino acid sequence given in first source; encoded by gene vi in the cauliflower mosaic virus genome
virosecurinine: isomer of the securinine group of alkaloids; isolated from plant securinega virosa
virotoxins: monocyclic toxic peptides found in amanita virosa mushrooms; main component viroisin; similar in structure to phallatoxins; general ; see also records for viroidin & viroisin
virulence factor p28, Ectromelia virus: acts upstream of caspase-3 in response to uv light-induced apoptosis; amino acid sequence known
virus activating protease: endoprotease from chick embryo; activates para- and orthomyoxovirus fusion glycoproteins by cleaving them at a single arginine site; ca(2+) dependent; similar to blood clotting factor x
virus protein 4, infectious bursal disease virus strain P2: lacks an atpase domain; a member of the lon protease family; partial amino acid
virus-infection-associated antigen, Foot-and-mouth disease virus: via antigen is comprised mainly of the rna polymerase 3d protein; prepared from inactivated foot-and-mouth disease (fmd) vaccine
vis protein, Drosophila: results suggest that vismay and achintya help to specify the spermatogenesis program by recruiting or stabilizing always early and cookie monster to specific target genes that need to be transcriptionally regulated during testes development; amino acid ; refseq nm_078990
viscosin: cyclic peptide lactone with alternating d and l amino acids; found in pseudomonas viscosa; amino acid sequence given in first source
viscosine: a gaba-a receptor agonist with anxiolytic and anticonvulsant activities; isolated from dodonaea viscosa
viscothionin: 9k peptide from korean mistletoe, improves nonalcoholic fatty liver disease
viscotoxin: 5 kda, 46 aa peptide from viscum related to other thionins; do not confuse with other proteins from viscum
viscotoxin A3, Viscum album: viscotoxins are 5 kda peptides that are thought to interact with biomembranes, displaying different toxic activities against a varied number of cell types; amino acid
viscotoxin B, Viscum album: viscotoxins are 5 kda peptides that are thought to interact with biomembranes, displaying different toxic activities against a varied number of cell types; amino acid
viscum album peptide: tumor reducing peptide isolated from viscum album extract (iscador)
viscum fraxini-2: an antineoplastic agent, phytogenic; extract from viscum album
viscumneoside IV: ; isolated from viscum colaratum (kom) nakai (hu-ji-sheng)
viscumneoside IX: isolated from stems and leaves of viscum coloratum; has inhibitory effects on osteoclast formation
viscumneoside X: isolated from stems and leaves of viscum coloratum; has inhibitory effects on osteoclast formation
vishnu: lytic peptide; composed of 19-amino acid residues; may have some potential as an embryo culture medium additive to enhance in vitro growth rate of murine fibroblasts; amino acid sequence given in first source
visilizumab: a humanized non-fcr-binding anti-cd3 antibody for treatment of steroid-refractory acute graft-versus-host disease
visinin: mw 24,000 protein; found in chick retina & rat brain
visnadin: was mh 1975-91 (see under benzopyrans 1975-90)
vistagan-liquifilm: combination of levobunolol, benzalkonium chloride, edta, sodium sulfate & polyvinyl alcohol
visthesia: an ophthalmic viscosurgical device that consists of lidocaine hydrochloride and sodium hyaluronate
vistusertib: potent and selective dual mtorc1 and mtorc2 inhibitor
vitacic: combination of adenosine, thymidine, cytidine, uridine, gmp; used in therapy of corneal diseases
vitagrin: combination of vitamicin-1 & kormogrisein-40; no further information available 3/89
vitamin A, pentifyllin, nicotinic acid, and vitamin E combination: contains 400mg pentifyllin, 100mg nicotinic acid, 30000 i.e. vitamin a & 40 i.e. vitamin e
vitamin A, vitamin E, vitamin K3 drug combination: consists of a mixture of vitamins a, e, and k3; effective in wound healing
vitamin A-aldehyde-dihydropyridine-ethanolamine: a retinal pigment epithelium lipofuscin compound
vitamin A-aldehyde-dihydropyridine-phosphatidylethanolamine: a retinal pigment epithelium lipofuscin compound
vitamin B12 receptor protein, human: cellular uptake of vitamin b(12) (cobalamin, cbl) is mediated by a receptor expressed on the plasma membrane that binds transcobalamin with cbl and internalizes the tc-cbl by endocytosis
vitamin B12-modified dextran-g-polyethylene oxide cetyl ether: used to form micelles for drug delivery via the vitamin b12 pathway
vitamin B2-aldehyde-forming enzyme: dichlorophenolindophenol used as acceptor; nadph required under aerobic but not anaerobic conditions; converts riboflavin to riboflavinal (7,8-dimethyl-10-(2,3,4-trihydroxy-4-butyl)isoalloxazine
vitamin C2 (flavan derivative): do not confuse with vitamin c2 synonym for esculin
vitamin D-binding protein-macrophage activating factor: formed when deglycosylated at o-linked site near c-terminus; incubation of human group-specific component with mixture of beta-galactosidase and sialidase generates macrophage activating factor, gcmaf
vitamycin: carotenoid produced by acrinomycetes used as vitamin a substitute in fowl
viteagnusin I: isolated from the fruits of vitex agnus-castus l.
vitedoamine A: phenylnaphthalene-type lignan alkaloid fom the seeds of vitex negundo
vitedoamine B: nitric oxide scavenging lignan alkaloid from vitex negundo seeds
vitedoin A: phenyldihydronaphthalene-type lignan from the seeds of vitex negundo
vitedoin B: trinorlabdane-type diterpene from the seeds of vitex negundo
vitellin-degrading protease: amino acid sequence given in first source; has high homology to trypsin-like proteases
vitelline protein B1, Fasciola hepatica: amino acid sequence given in first source; isolated from fasciola hepatica; a 31-kda eggshell protein; genbank m93024
vitelline protein B2, Fasciola hepatica: amino acid sequence given in first source; isolated from fasciola hepatica; a 31-kda eggshell protein with high homology with vpb1; genbank m93025
vitellogenesis inhibiting hormone: amino acid sequence given in first source; 77 amino acid residues; mw 9135 da; has 2 isoforms (inactive and active); from lobster homarus americanus
vitellogenin receptor, Aedes aegypti: from the yellow fever mosquito; related to drosophila yokeless protein; genbank l77800
vitespin: contains heat-shock protein 96; in phase ii study of therapy in patients with indolent non-hodgkin's lymphoma (5/2004)
vitexdoin A: nitric oxide scavenging lignan from vitex negundo seeds
vitexfolin A: from extract of viticis fructus, a dried fruit of vitex rotundifoliia
vitexin: an apigenin flavone found in pennisetum millet (pearl millet) that inhibits thyroid peroxidase contributing to goiter
vitexin-2-O-rhamnoside: from leaves and seeds of beta vulgaris leaves
vitexin-2-O-xyloside: from leaves and seeds of beta vulgaris leaves
vitilevuamide: a bicyclic 13 amino acid peptide from two marine ascidians, didemnum cuculiferum and polysyncranton lithostrotum
vitisinol C: nootropic from vitis vinifera grapevine shoots extracts
vito protein, Drosophila: nucleolar protein; refseq nm_168136
vitopine synthase: amino acid sequence given in first source; isolated from agrobacterium vitis
vitronectin-binding protein, Staphylococcus aureus: 60 kda; n-terminal amino acid sequence given in first source
vitronectin-like protein, Physarum polycephalum: a 70-kda protein isolated from physarum polycephalum; an arg-gly-asp-dependent, cell-spreading protein; nh2-terminal sequence given in first source
vittatalactone: a beta-lactone from the striped cucumber beetle, acalymma vittatum
vlasoulamine A: sesquiterpene lactone dimer featuring a fully hydrogenated pyrrolo(2,1,5- cd)indolizine core
vllY protein, Vibrio vulnificus: isolated from vibrio vulnificus; amino acid ; genbank u97357
vlpB protein, Mycoplasma hyorhinis: amino acid sequence given in first source
vlpD protein, Mycoplasma hyorhinis: isolated from mycoplasma hyorhinis; amino acid ; genbank u35016
vls protein, Drosophila: encodes a divergent wd protein that is required for vasa localization and oskar protein accumulation; refseq nm_136175
vmp protein, Borrelia: abundant outer membrane lipoprotein whose espression varies with the environment; has been sequenced
vn protein, Drosophila: a component of the epidermal growth factor receptor pathway with similarity to the neuregulins; rn refers to isoform 1; amino acid ; refseq nm_079218
vnd protein, Drosophila: involved in the early development of cns in drosophila
voachalotine: from the roots of tabernaemontana catharinensis (apocynaceae)
vocara: austrian medicine containing sage, belladonna, laconos, lachesis, haneman mercurius in homeopathic dilutions, and ethyl alcohol; used for respiratory tract diseases with high clinical effectiveness
vocimagene amiretrorepvec: a retroviral replicating vector based on a modified murine leukemia virus (mlv). it contains a transgene for modified yeast cytosine deaminase (cd)
voclosporin: semi-synthetic cyclosporine a analog & calcineurin inhibitor; fda approved use to treat lupus nephritis
vof-16 long non-coding RNA, rat: may be related to the cognitive impairment induced by chronic ischemia after 2vo; refseq nr_037614
vofatamab: an igg1antibody to fgfr3 for the treatment of t(4;14)-positive multiple myeloma
volagidemab: igg2 monoclonal antibody against the human glucagon receptor for treatment of type i diabetes
volinanserin: blocks 3,4-methylenedioxymethamphetamine (mdma)-stimulated dopamine synthesis in vivo without affecting basal synthesis
volkendusin diacetate: from the leaves and twigs of trichilia reticulatafrom the leaves and twigs of trichilia reticulata (meliaceae)
volkensin: a type 2 ribosome-inactivating protein; 1569-bp orf (523 amino acid residues) without introns, with an internal linker sequence of 45 bp; from roots of adenia volkensii harms (kilyambiti plant); contains two free cysteinyl residues out of 14 derived from the gene sequence
volociximab: an anti-alpha5beta1 integrin antibody as anti-angiogenic agent
volonomycin: from streptomyces paulus; appears to be similar to senfolomycin and proceomycin but seems to have more nitrogen and sulfur; nmr indicates seven methyl groups and possible acetyl
voltage-dependent calcium channel (P-Q type): refseq nm_001252059 (isoform 2, mouse)
voltage-sensor-containing phosphatase, Ciona intestinalis: this voltage-dependent phosphatase was unearthed by sequence gazing at the genome of the ascidian ciona intestinalis and was termed ci-vsp to reflect the presence of both a voltage sensor and a phosphatase
volvatoxin A2 protein, Volvariella volvacea: a pore forming hemolytic fungal cardiotoxic protein; isolated from the edible mushroom, vovlariella volvacea; mw 24 kda; has 199 amino acid residues; has been sequenced
vomifoliol 9-O-arabinofuranosyl-(1-6)-glucopyranoside: stimulates glucose uptake; isolated from the leaves of diospyros kaki
vomifoliol 9-O-glucopyranosyl-4-O-xylopyranosyl-6-O-glucopyranoside: ; isolated from apple fruit pulp
von Willebrand factor (445-733): reduced and recombinant form of von willebrand factor (445-733) that antagonizes the platelet glycoprotein ib receptor; fibrinogen receptor antagonist
von Willebrand factor (504-728): represents approximately 10% of the sequence of mature von willebrand factor; an antagonist of von willebrand-glycoprotein ib binding domain
von Willebrand factor Normandy: abnormal von willebrand factor in which thr(28) is replaced by methionine; mimics hemophilia a
vorolanib: multikinase vascular endothelial growth factor (vegf) receptor/platelet-derived growth factor (pdgf) receptor inhibitor
vorozole: ; vorozole/r 83842 is ((+)/dextro-isomer), rn 129731-10-8; r 83839 ((-)/levo-isomer)
vosaroxin: has antineoplastic activity; vosaroxin was formerly voreloxin
vouacapan: ; a furan-diterpene extracted from seeds of pterodon polygalaeflorus
voxelotor: inhibits polymerization of hemoglobin s for the treatment of sickle cell disease
vps39 vacuolar protein sorting 39, Danio rerio: refseq nm_001113540.1; np_001107012.1
vpu protein, Human immunodeficiency virus 1: an accessary protein that is unique to hiv-1; viroporin refers to the ion channel aspect of vpu
vrg protein, Bordetella pertussis: from bordetella pertussis; consensus dna sequence located in the vrg coding region is sufficient to confer vrg transcriptional regulation, & this site in the dna is specifically recognized by a 34 kda repressor of the vir-repressed genes; amino acid sequence known; five types of the vir-repressed genes have been identified; vrg 6, 18, 24, 53, and 73 from bordetella pertussis
vri protein, Drosophila: member of bzip family of transcription factors; vrille gene is a maternal enhancer of decapentaplegic; refseq nm_057843
vseap1 protein, Mesocricetus auratus: interacts with c-terminal part of v-srchmc & has 68% homology with rna-gadd7/adapt15; genbank aj003192
vspB protein, Glycine max: accumulate in leaves of soybean when the plants are continually depodded; have acid phosphatase activity on polyphosphates; amino acid sequence known
vsr endonuclease: from e coli, nicks double-stranded dna which has been damaged to have thymidine residues mismatched to 2'-deoxyguanosine thus initiating vsp mismatch repair
vsrB protein, Pseudomonas solanacearum: a regulator of virulence genes of pseudomonas solanacearum; homologous to sensors of the two-component regulator family; aa sequence given in first source; genbank l21173
vstaminol C: from orthosiphon stamineus of taiwan; has nitric oxide inhibitory activity
vsx1 protein, zebrafish: a chx10-like gene product expressed in overlapping domains
vsx2 protein, zebrafish: homologous to chx10 and vsx-1; isolated from zebrafish retinal neuroepithelium; amino acid
vtd protein, Drosophila: a rad21 homologue expressed in s-phase cells in drosophila; encodes a product involved in mitotic sister chromatid cohesion which is a component of the cohesin complex; refseq nm_001015132
vulgarin (eudesmane): eudesmane lactone from artemisia canariensis; vulgarin (isoflavone) is also available
vulgarinin, Phaseolus vulgaris: has both antifungal and antineoplastic activities; isolated from haricot beans; n-terminal amino acid
vulgarone B: sesquiterpene ketone antifungal constituent in the steam-distilled fraction of artemisia douglasiana
vulgaside I: from spikes of prunella vulgaris l., inhibits glycogen phosphorylase and improve insulin sensitivity in 3t3-l1 adipocytes
vulgaside II: from spikes of prunella vulgaris l., inhibits glycogen phosphorylase and improve insulin sensitivity in 3t3-l1 adipocytes
vulpecholic acid: bile acid from australian opossum, trichosurus vulpecula
vulpinic acid: rn given refers to cpd without isomeric designation; ; vulpinic acid refers to (e)-isomer
vupanorsen: an antisense oligonucleotide targeting hepatic angptl3 mrna for degradation
vvP protein, Vibrio vulnificus: forms hemorrhagic lesions & causes extensive dermonecrosis; enhances vascular permeability through histamine release & bradykinin generation by activation of the plasma kallikrein -kinin system; immediately inactivated by plasma protein; genbank u48780
w protein, Drosophila: involved in the control of adult eyecolor; similar to components of active transport complexes; necessary for uptake of pteridine precursors; refseq nm_057439
waglerin: venom of wagler's pit viper, trimeresurus wagleri; amino acid sequence given in first source
waiakeamide: an antifouling hexapeptide from a palauan sponge, haliclona sp.
waikialoid A: from aspergillus; suppresses hyphal morphogenesis and inhibits biofilm development in pathogenic candida albicans
waixenicin A: a trpm7 channel inhibitor with antineoplastic activity; isolated from the soft coral sarcothelia edmondsoni
waldiomycin: inhibits walk histidine kinase; isolated from streptomyces
walkmycin B: a di-anthracenone antibiotic, chemical formula c(44)h(44)cl(2)o(14)
wallitaxane A: potent alpha-glucosidase inhibitor and cytotoxic cpd from the stem bark of taxus wallichiana
walsucochin A: isolated from walsura cochinchinensis; exhibited significant cell protecting activities against h2o2-induced pc12 cell damage
walsucochin B: isolated from walsura cochinchinensis; exhibited significant cell protecting activities against h2o2-induced pc12 cell damage
walsunoid A: 11beta-hsd1 inhibitor from walsura robusta
waltherine: cholinesterase inhibitor from leaves of waltheria brachypetala
waltherione-B: cholinesterase inhibitor from leaves of waltheria brachypetala
wapA protein, Bacillus subtilis: gene wapa encodes a protein precursor of 258 kda; wap - wall-associated protein; amino acid sequence given in first source; genbank l05634
wapl-1 protein, C elegans: cele_r08c7.10; refseq nm_068166
warangalone-4'-methyl ether: a natural product from the roots of hedysarum multijugum
warfarin hexadecyl ether: model of lipophilic agent for drug targeting to tumor cells with increased ldl receptor activity
wariai protein, Dictyostelium: encodes a protein with a homeobox and seven ankyrin repeats; regulates anterior-posterior patterning and cell-type homeostasis; amino acid
warifteine: tertiary bis-benzylisoquinoline base alkaloid with p-xylyl moiety from plant cissampelos ovalifolia d.c.; used by amazon indians for medicinal purposes; rn given refers to di-hcl
warnericin RB4, Staphylococcus warneri: may prove useful in inhibiting growth of microorganisms in fruit juice drinks; amino acid
warnericin RK, Staphylococcus warneri: specifically active against legionella
wasalexin A: wasalexins a and b are geometrical isomers; isolated from wasabia japonica
washing blue: used in treatment of ringworm; contains ultramarine, indigo, prussian blue, methylene blue, aniline blue with starch, clay, gypsum, chalk and sometimes glycerin; also used for blueing laundry
waspergillamide A: from an australian mud dauber wasp-associated aspergillus sp.
watasemycin A: isolated from streptomyces; watasemycin possesses a methyl group at 5'-position of thiazostatin instead of a hydrogen atom
water soluble chitin: chitin that is partially deacetylated with molecular weight determined by alkaline and ultrasonic treatment
wattisine A: cytotoxic alkaloid from the roots of cyclea wattii
wattisine B: cytotoxic alkaloid from the roots of cyclea wattii
wax synthase, human: a member of the dgat2/mgat family; ay611031 and ay611032
wax synthase, mouse: a member of the dgat2/mgat family; ay611031 and ay611032
waxy protein, plant: from maize; encoded in nucleus; has a 7 kda transit peptide at the amino-terminus of its 66 kda precursor
wb protein, Drosophila: a laminin alpha chain protein isolated from drosophila; required for cell adhesion and migration; amino acid ; refseq nm_165086
wbbI protein, E coli: wbbi showed a modest preference for pyranoside acceptor substrates of the alpha-d-gluco-configuration but it also possessed the ability to turn-over acceptor analogues
wbl protein, Drosophila: required for dorsoventral patterning; isolated from drosophila; amino acid ; refseq nm_166339
wbpM protein, Pseudomonas aeruginosa: inner membrane protein from pseudomonas aeroginosa essential for b-band lipopolysaccharide biosynthesis; genbank af508154
wc-1 protein, Neurospora crassa: required for blue-light perception/signal transduction in neurospora and other fungal species; genbank x94300
wcaG protein, E coli: catalyzes conversion of gdp-4-keto-6-deoxy-d-mannose to gdp-l-fucose
wdlA protein, Streptomyces lincolnensis: genbank af116463
wdp protein, Drosophila: genbank af395331; refseq nm_166524
wecA protein, E coli: catalyzes the transfer of n-acetylglucosamine phosphate to undecaprenol phosphate; an undecaprenol-p-p-glcnac synthetase
wecB protein, E coli: a 42 kda cytoplasmic protein required for bacteriophage n4 adsorption;also catalyzes the reversible epimerization at c-2 of udp-n-acetylglucosamine (udp-glcnac); amino acid sequence given in first source; genbank l18799
wedelolactone: antihepatotoxic coumestan from eclipta prostrata and wedelia calendulacea (both asteraceae)
wee-1.3 protein, C elegans: a membrane-associated protein; phosphorylates cdc2 on both threonine-14 and tyrosine-15; a member of the wee1 kinase family
wee1 protein, S pombe: involved in negative regulation of mitosis; may exerts its inhibitory effects by regulating the phosphorylation of p34(cdc2); genbank m16508
weibizhi: for treatment of gastric ulcers; consists of licorice, cortex frangulae, and fructus foeniculi, and three synthetic drugs unknown in first source
weifuchun: composed of panax ginseng, isodon amethystoides, and bran fried hovenia dulcis
weiganli: relieves myelosuppresion induced by radiation and chemotherapeutic drugs
weinaokang: protects against vascular injury; consists of compounds extracted from ginkgo, ginseng, and saffron
weipixiao: used to treat gastric precancerous lesions; consists of radix astragali, radix pseudostellariae, rhizoma atractylodis macrocephalae, radix salviae miltiorrhizae, and herba hedyotis diffusae
weiqi: has antineoplastic activity; consists of radix angelicae sinensis, radix astragali, radix codonopsis, rhizoma curcumae, fructus aurantii, fructus akebiae, and herba taraxaci
weissellicin 110: from weissella cibaria 110, isolated from plaa-som, a fermented fish product from thailand; genbank ab261010
weissellin A protein, Weissella paramesenteroides: genbank jn820316
wek protein, Drosophila: zinc finger adaptor of the toll pathway in dorsoventral patterning of the drosophila embryo; refseq nm_080191
welan: non-gelling polysaccharide produced by alcalingenes atcc 31555
welwitindolinone B isothiocyanate: from blue-green alga hapalosiphon welwitschii
welwitindolinone C isothiocyanate: from blue-green alga hapalosiphon welwitschii
wen luo yin: used to treat rheumatoid arthritis; composed of aconitum carmichaelii, cinnamomum cassia, atractylodes macrocephala, and selaginella tamariscina
wen-xin: has cardioprotective activity; composed of ginseng radix et rhizoma, cinnamomi ramulus, allii macrostemonis bulbus, trichosanthis fructus, pinelliae rhizoma praeparatum cum alumine, paeoniae radix rubra, ophiopogonis radix, and coptidis rhizoma
wendan xiezhuo: improves vascular endothelial diastolic function and atherosclerosis
wenhua juanbi: used to treat collagen-inducing arthritis; consists of radix saposhnikoviae, radix et rhizoma clematidis, scolopendra, semen sinapis albae, buthus martensii, radix angelicae, bombyx batryticatus, semen coicis, rhizoma corydalis, caulis lonicerae, radix salviae miltiorrhizae, rhizoma atractylodes alba
wenpi decoction: a recipe from sun simiao's 'qian jin yao fang' containing rheum, radix aconiti, zingiber officinale, ginseng and glycyrrhiza that delays progression of chronic renal failure
wenshen xiaozheng tang: for treatment of endometriosis; consists of typha angustifolia, trogopterus xanthipes milne-edward, draconis sanguis, leguminosae, radix dipsaci asperoidis, commiphora myrrha, corydalis yanhusuo, and fructus meliae toosendan
wentilactone B: previously reported structure incorrect; hydroxy group found to be in 2alpha-position instead
wenxia changfu: has antineoplastic activity; consists of radix aconiti praeparatae, radix et rhizoma rhei, panax ginseng, and angelica sinensis
wenxiao: used to treat atherosclerosis; consists of hirudo , pheretima , radix salviae miltiorrhizae , cortex moutan, radix curcumae, and rhizoma pinelliae
wenxin keli: consists of dangshen (codonopsis radix), huangjing (polygonati rhizoma), sanqi (notoginseng radix et rhizoma), hupo (ambrum), and gansong (nardostachyos radix et rhizoma)
wenyangbushen: used to treat steroid-induced avascular necrosis of the femoral head; consists of morinda, epimedium, drynaria, deerhorn gelatin, salvia miltiorrhiza, radix curcumae, panax pseudoginseng, astragalus, achyranthes, and licorice
westiellamide: from blue-green algae westiellopsis prolifica; also from the marine ascidian lissoclinum bistratum
wetA protein, Aspergillus nidulans: amino acid sequence given in first source; activates spore-specific gene expression
wewakpeptin A: cytotoxic cyclic depsipeptide from a papua new guinea collection of the marine cyanobacterium lyngbya semiplena
wewakpeptin B: cytotoxic cyclic depsipeptide from a papua new guinea collection of the marine cyanobacterium lyngbya semiplena
wge protein, Drosophila: a bromo-adjacent homology domain protein involved in disc-specific identity; refseq nm_001043281
wgn protein, Drosophila: required for eiger signaling; amino acid ; refseq nm_167626
wheat germ agglutinin-apohorseradish peroxidase conjugate gold complex: used as neuronal marker for long-term tracing studies
wheat germ agglutinin-ferritin: binds both sialic acid & n-acetylglucosamine sugar residues
wheat germ agglutinin-gold: used to locate specific carbohydrates in the cochlea
wheat germ agglutinin-ricin A-chain conjugate: neuronotoxic after vagal injection
wheat germ trypsin inhibitor: mw i=14,000; mw ii=7,000; double- & single-headed inhibitors of bowman-birk type; amino acid sequences given in first source suggest presence of duplicated structures
wheat peroxidase: gene of this enzyme is neither pathogen- nor wound-induced in leaves but is constitutively expressed in roots; amino acid sequence given in first source
wheylin-1 peptide: anti-anxiety agents; beta-lactoglobulin-derived peptide
wheylin-2 peptide: anti-anxiety agents; beta-lactoglobulin-derived peptide
whiB protein, Streptomyces: a transcription regulatory protein; regulates sporulation in bacteria
whiG protein, Streptomyces coelicolor: amino acid sequence given in first source; from streptomyces coelicolor hyphae; rna polymerase sigma factor
whiH protein, Streptomyces: one of loci needed for the orderly multiple sporulation septation of aerial hyphae of streptomyces sp.; genbank af096293
whiL protein, Streptomyces coelicolor: a response regulator-like protein that functions at an intermediate stage of sporulation in streptomyces coelicolor; amino acid ; genbank al023702
white collar 2 protein, Neurospora: required for blue-light perception/signal transduction in neurospora crassa; genbank y09119
white-line-inducing principle, Lasiosphaera fenzlii: has both antibacterial and antineoplastic activities; isolated from the puffball lasiosphaera fenzlii
wickerol A: isolated from the fungus trichoderma atroviride; has antiviral activity against type a, h1n1 influenza virus
wikstroelide E: daphnane diterpene from the buds of wikstroemia chamaedaphne
wikstroelide M: has anti-hiv activity; isolated from daphne acutiloba
wikstroelide Q: from the buds of wikstroemia chamaedaphne
wilfordlongine: isolated from tripterygium wilfordii; ; note that article also refers to this as both wilfordlonging and wilfordclonine
wilfortrine: from trypterygium wilfordii hook; rn given in toxlit
wilsoniamine A: from the temperate australian bryozoan, amathia wilsoni
wilsoniamine B: from the temperate australian bryozoan, amathia wilsoni
wilsonilignan A: anti-hiv-1 compound from the fruits of schisandra wilsoniana
wilsonilignan B: anti-hiv-1 compound from the fruits of schisandra wilsoniana
wilsonilignan C: anti-hiv-1 compound from the fruits of schisandra wilsoniana
win1 protein, S pombe: a map kinase kinase (mapkk) responsible for osmostress signaling; isolated from schizosaccharomyces pombe; refseq nm_001020285
win4 protein, Populus balsamifera: wound-inducible protein from poplar leaves; related in sequence and chromosomal location to poplar bark storage protein; has been sequenced
winged bean lectin: from raw winged beans, psophocarpus tetragonolobus
wingless protein, Sarcophaga: isolated from the leg imaginal discs of sarcophaga; amino acid
wintergreen oil: essential oil from gaultheria plant or betula bark that contains methylsalicylate, guaiacol, & cresol
wis1 protein, S pombe: a map kinase kinase homolog; has homology to the serine-threonine family of protein kinases; phosphorylates spc1/styi; genbank x62631
wis4 protein, S pombe: a map kinase kinase kinase (mapkkk); phosphorylates wis1; genbank y07750
wisanine: from roots of piper guineense; rn given refers to (e,e)-isomer
wiskostatin: induces folding of n-wasp's gtpase-binding domain into its autoinhibited conformation
wisteria lectin: selectively binds n-acetylgalactosamines beta 1 (galnac beta 1-3 gal) residues of glycoproteins
wit 3.0 protein, human: expressed in edentulous oral mucosa undergoing tooth extraction wound-healing; encodes splice variants, wit 3.0 alpha and wit 3.0 beta; homologous to wit3.0 protein from rat; amino acid
wit protein, Drosophila: regulates neuromuscular synapse morphology and fuction; amino acid
witepsol: suppository base containing neutral fatty substances, mainly saturated fatty acid triglycerides
withacnistin: withanolide from airdried leaves of iochroma gesnerioides
withaferin A: an antiestrogen and phytogenic antineoplastic agent isolated from leaves of withania somnifera dun.
withalongolide A 4,19,27-triacetate: has antineoplastic activity; isolated from physalis longifolia
withanamide A: prevents amyloid fibril formation; isolated from withania somnifera
withanamide C: prevents amyloid fibril formation; isolated from withania somnifera
withangulatin A: a withanolide from physalis angulata; promotes type ii dna topoisomerase-mediated dna damage
withangulatin I: a cytotoxic withanolide from physalis angulata; ; different from withanolide 1
withaphysalin C: naturally occurring steroidal lactone of the withanolide group
withaphysalin F: from the leaves of acnistus arborescens (solanaceae)
withaphysalin M: cytotoxic withaphysalin from the leaves of acnistus arborescens
withaphysalin N: cytotoxic withaphysalin from the leaves of acnistus arborescens
withaphysalin O: cytotoxic withaphysalin from the leaves of acnistus arborescens
wlaB protein, Campylobacter jejuni: from campylobacter jejuni; involved in transport of lipopolysaccharide molecules across the cytoplasmic membrane; genbank y11648
wlaG protein, Campylobacter jejuni: involeved in lipopolysaccharide synthesis in campylobacter jejuni; amino acid ; genbank y11648
wls protein, zebrafish: involved in wnt transport; refseq nm_213146
wnd protein, Drosophila: wallenda is both necessary for highwire synaptic overgrowth and sufficient to promote synaptic overgrowth, and synaptic levels of wallenda protein are controlled by highwire and ubiquitin hydrolases; refseq nm_140880
wnk-1 protein, C elegans: functions upstream of gck-3 in a manner similar to that postulated for its mammalian homologs; refseq nm_001268438
wnt2ba protein, zebrafish: wnt genes encode a family of secreted short-range signaling glycoproteins that are important in cell differentiation and development; refseq nm_182876
wnt8a protein, zebrafish: involved in developmental pathway in zebrafish; refseq nm_130946
wogonin 7-O-beta-D-ethylglucuronide: antioxidant from scutellaria baicalensis georgi
wogonin-5-0-beta-D-glucuronide methyl ester: flavonoid glucoside from huanglianjiedutang decoction
wolframin protein: encoding a transmembrane protein is mutated in patients with diabetes mellitus and optic atrophy; amino acid
wood vinegar: a volatile, complex combination obtained by the destructive distillation of wood; main ingredients are acetic acid & methanol
woodfordin C: ; macro-ring tannin dimer with anti-tumor activity from woodfordia fruticosa
woodrosin I: ; a resin glycoside from the stem of ipomoea tuberosa
woodrosin II: ; a resin glycoside from the stem of ipomoea tuberosa
woodsianone A: antiplasmodial from the flowers of the australian tree angophora woodsiana
woodsianone B: antiplasmodial from the flowers of the australian tree angophora woodsiana
wor protein, Drosophila: involved in neurogenesis in drosophila; refseq nm_057253
wortmannin-sensitive and insulin-sensitive protein kinase, rat: activates cardiac 6-phosphofructo-2-kinase
wortmannolol: a monoamine oxidase inhibitor; isolated from talaromyces
wortmannolone: an nf-kappab inhibitor; isolated from taxus fuana
wound-inducible ribonuclease, Nicotiana: isolated from nicotiana glutinosa leaves; amino acid
wound-inducible transcript 3.0, rat: may be involved in wound closure of oral mucosa; amino acid
wrapper protein, Drosophila: a member of the ig superfamily, is expressed by midline glia and is required for them to ensheath commissural axons in drosophila; amino acid
wtrw protein, Drosophila: cg31284, named by the authors water witch (wtrw) is required to detect moist air;refseq nm_169201.1; np_731194.1 cg31284-pb isoform b
wts protein, Drosophila: putative protein kinase from drosophila melanogaster; amino acid ; refseq nm_170524
wu-tou: used to treat rheumatic arthritis and joint pain; consists of aconitum carmichaeli, ephedra sinica, paeonia lactiflora, astragalus membranaceus, and glycyrrhiza uralensis
wu-zi-yan-zong-wan: includes extracts of lycium barbarum l., rubus chingii hu, cuscuta chinensis lam, schisandra chinensis (turcz.) baill., and plantago asiatica l
wubangziside A: xanthone glycoside from root bark of polygala caudata
wubangziside B: xanthone glycoside from root bark of polygala caudata
wufuxinnaoqing: for treatment of chronic stable angina; consists of refined safflower oil, borneol, vitamin e, and vitamin b6
wuho protein, Drosophila: a wd40 repeat protein involved in germline cell development
wuji wan formula: contains: rhizoma coptidis, frutus evodiae rutaecarpae and radix paeoniae alba for treatment of intestinal disorders
wulingsan: contains poria, alismatis rhizoma, atractylodis rhizoma, cinnamomi ramus, & polyporus; suppressed the development of nephrocalcinosis induced by a high phosphorus diet in young rats
wulingzhic acid: isolated from excreta of trogopterus xanthipes milne-edwards
wumei: famous herbal formula used widely in chinese herbal medicine for centuries. originated from treatise on cold damage and miscellaneous diseases (200-210, ad), consisting of 10 herbs: fructus mume(wm), radix angelicae sinensis(dg), rhizoma radix asari(xx), radix aconiti lateralis praeparata(fz), cortex phellodendri(hb), pericarpium zanthoxyli(hj), ramulus cinnamomi(gz), radix ginseng(rs), rhizoma coptidis(hl) and rhizoma zingiberis(gj)
wun protein, Drosophila: involved in guiding the germ cells early in the embryonic development; maybe involved in lipid metabolism; amino acid sequence given in first source; refseq nm_057845
wushanicariin: isolated from epimedium wushanense t.s. ying
wutaienin C-7 methyl ether: isolated from zanthoxylum wutaiense
wuweizidilactone Q: from the stems and leaves of schisandra viridis
wuxistatin: an hmg-coa reductase inhibitor from fermentation broth of amycolatopsis sp.
wuyaoshunqisan: contains: ephedrae herba, aurantii nobilis pericarpium, linderae radix, cnidii rhizoma, agelicae daburicae radix, bombycis corpus, aurantii fructus, platicodi radix, zingiberis rhizoma siccum, glycyrrhizae radix & zingiberis rhizoma
wuzhi: an extract of schisandra sphenanthera; used to prevent drug-induced hepatitis
wuzhigan: composed of wuzhigan, shidagonglao, gangmei, shanzhima for treatment of common cold, in randomized, double-blind, multi-center trial
wuzhuyurutine B: indoloquinazoline alkaloid from evodiae fructuss
wzc protein, E coli: required for the extracellular polysaccharide colanic acid synthesis; the autophosphorylated form is inactive; probably involved in the export of colanic acid from the cell to mediuman autophosphorylating protein-tyrosine kinase; amino acid
wzx protein, Streptococcus pneumoniae: a capsular polysaccharide polymerase; has been sequenced