NLK-NML/MeSH-CZ-2025-notes huggingface dataset:
Dsg1c protein, mouse: member of the mouse desmoglein gene family; expressed in brain, skeletal muscle, and liver, among other tissues; similar to dsg2 in its tissue distribution; refseq nm_181680
Dsg4 protein, mouse: mouse homolog of human desmoglein 4; expressed in epidermis during mouse development; refseq nm_181564
Dsg4 protein, rat: mutation of dsg4 gene leads to lanceolate hair phenotype; refseq nm_199490
Dsip1 protein, mouse: a dexamethasone-induced gene product involved in glucocorticoid hormone-induced modulation of gene expression and regulation of t-cell death; refseq nm_010286
Dsk1 protein kinase: phosphorylates prp2 and is involved in pre-mrna splicing; isolated from schizosaccharomyces pombe
Dsor1 protein, Drosophila: a map kinase kinase from drosophila melanogaster
DspA protein, Erwinia amylovora: pathogenicity factor isolated from erwinia amylovora; amino acid ; genbank y13831; do not confuse with dspa, isolated from bat
DsrA RNA, E coli: a small, untranslated rna that antagonizes the h-ns (histone-like protein)-mediated silencing of numerous promoters; embo j 1996 aug 1;15(15):3993-4000
Dss1 protein, Arabidopsis: binds brca2 protein; genbank aj619975 (dss1-1) and aj619976 (dss1-2)
Dss1 protein, S pombe: associates with the proteasome; has been sequenced
Dtnbp1 protein, mouse: plays a role in the biogenesis of lysosome-related organelles such as platelet dense granule and melanosomes; binds dystrobrevins in brain in muscle; refseq nm_025772
Dtr1 protein, S cerevisiae: an amine/polyamine transporter involved in multidrug resistance and spore wall maturation; has been sequenced
DtwP-HepB-Hib vaccine: a fully liquid pentavalent vaccine
DtxR protein, Corynebacterium diphtheriae: binding of dtxr to the tox operator requires divalent heavy metal ions & a 9-base-pair interrupted palindromic sequence; amino acid sequence has been determined
DuP 925: exhibits antiviral activity by inhibiting reverse transcriptase following intravenous administration
Dub1 protein, mouse: dub - deubiquitinating; a deubiquitinating enzyme with growth suppressing activity; refseq nm_007887
Dub2a protein, mouse: a hematopoietic deubiquitinating enzyme; genbank 407172
Duffy antigen binding protein, Plasmodium: located within the micronemes of invasive malaria merozoites
Dukoral: an oral vaccine containong very small amounts of dead cholera bacteria and nontoxic components of cholera toxin
Duo-Bonharen: viscoelastic preparation containing hyaluronic acid, prepared by bacterial fermentation for ophthalmosurgery
Duogestral: an european contraceptive drug containing both estrogenic and progestational activities; no other information available 8/25/81; structure unknown
Duox2 protein, rat: homolog of nadph oxidase flavoprotein involved in the thyroid h2o2 generator; refseq nm_024141
DupA protein, Helicobacter pylori: a duodenal ulcer-promoting protein; genbank ef076755
DuraPrep: a 0.7% solution of iodine in isopropyl alcohol for use in surgical prep
Durazym: a modified alkaline protease produced by recombinant dna techniques; available from novo nordisk (bagsvaerd, denmark)
Dusp7 protein, mouse: an erk signaling inhibitor; genbank ak140372
DvAMP antimicrobial peptide: dvamp is a novel antimicrobial peptide with antimicrobial activity with sequence: ekkpwarlrfkfkllkglakkmk
Dwarf3 protein, Zea mays: catalyzes a step in gibberellin synthesis; isolated from maize; amino acid
Dy(ethylenediamine): impermeant shift reagent used to induce a chemical shift across a membrane
DyNAzyme polymerase: commercial product from finnzymes used for gene amplification
Dycal: contains calcium hydroxide in catalyst paste mixed with zinc oxide & zinc stearate in ethyl toluene sulfonamide; base contains titanium dioxide & calcium tungstate in 1,3-butylene glycol disalicylate
DyeCycle Violet: a dna binding dye structurally similar to hoechst 33342
Dym protein, mouse: mutation in this protein results in dyggve-melchior-clausen dysplasia; refseq nm_027727
Dyrb-1 protein, C elegans: a dynein light chain involved in spindle positioning; genbank z54216
Dyrk1A protein, Xenopus: a dual specificity kinase; genbank bc044104
Dyt1 protein, mouse: an atp-binding protein, encoded by an early-onset torsion dystonia gene; defects in dyt1 are the cause of torsion dystonia 1 (dyt1), also known as primary or idiopathic dystonia; refseq nm_144884
Dz13 DNAzyme: a 10-23 dnazyme with a 3'-3'-linked inverted thymidine residue targeting the c-jun mrna
Dzip1 protein, zebrafish: involved in regulation of hedgehog signaling; genbank ab106357
E 117 peptide: has same amino acid sequence as somatotropin 110-127; does not stimulate nb2 mitogenesis
E 121 compound: an antiepileptic, anti-asthmatic, anti-inflammatory, and immunosuppressive agent
E 2011: e-2011 is the (1s,5r)-isomer; er-20593 is the (1r,5r)-isomer; a metabolite of er-4539; a potent mao-a inhibitor
E 25: e-25 referred to as hcl in chemline; rn given refers to (1r-(1alpha,4abeta,10aalpha))-isomer
E 3040: a dual inhibitor of 5-lipoxygenase and thromboxane a2 synthetase
E 4031: class iii anti-arrhythmia agent; structure given in ud
E 5555: a 2-iminopyridine derivative and platelet aggregation inhibitor
E 5880: platelet activating factor antagonist; rn given refers to chloride; rn for parent cpd not avail 2/92
E 6010: cysteine 84 in the epidermal growth factor domain is replaced by serine
E coli O18 O-specific polysaccharide-cholera toxin: o-specific polysaccharide isolated from serotype 18 escherichia coli lipopolysaccharide covalently coupled to cholera toxin
E coli O18 O-specific polysaccharide-toxin A: o-specific polysaccharide isolated from serotype 18 escherichia coli lipopolysaccharide covalenty coupled to pseudomonas aeruginosa toxin a
E colicin-binding immunity protein Im7, E coli: see also colicin immunity proteins
E colicin-binding immunity protein Im9, E coli: binds specifically to the dnase-type colicin e9 and inhibits its bactericidal activity; genbank x15858
E protein, Dengue virus type 3: amino acid sequence given in first source; sequences known for h87 and 1153 strains
E protein, Equine arteritis virus: essential for production of infectious progeny virus; amino acid
E protein, SARS coronavirus: an ion channel-containing viral envelope protein from severe acute respiratory syndrome (sars) coronavirus
E protein, bacteriophage X174: causes lysis of e. coli when expressed by phage, not an e coli protein
E(M) protein, Triticum aestivum: most abundant peptide in cytosolic fraction of dry wheat embryos; dna sequence encoding of this peptide given in first source
E(S)(beta) peptide: from the third hypervariable region of the e(s)(beta) chain of mhc class ii molecules; amino acid sequence has been determined
E(bx) protein, Drosophila: nucleosome remodeling factor large subunit; a component of a chromatin remodeling complex that is involved in nucleosome sliding; refseq nm_167819
E(rns) protein, classic swine fever virus: a pestivirus envelope glycoprotein with rnase activity; a disulfide-linked homodimer of 100 kda; it is found on the surface of pestivirus-infected cells and is secreted into the medium; amino acid
E(spl)m3-HLH protein, Drosophila: amino acid sequence given in first source; a hlh protein of the enhancer of split locus complex, e(spl)-c; refseq nm_079785
E(spl)m4-BFM protein, Drosophila: member of the e(spl)-complex; antagonizes notch mediated lateral inhibition; amino acid ; refseq nm_079786
E(spl)m7-HLH protein, Drosophila: enhancer of split protein; member of the e(spl)-complex; antagonizes notch mediated lateral inhibition; isolated from drosophila; amino acid ; refseq nm_080505
E(spl)m8-HLH protein, Drosophila: a notch effector; refseq nm_079789
E(spl)mbeta-HLH protein, Drosophila: a hlh protein of the enhancer of split locus complex, e(spl)-c; refseq nm_079781
E(spl)mdelta-HLH protein, Drosophila: has homology with bearded protein; amino acid ; refseq nm_079779
E(spl)mgamma-HLH protein, Drosophila: amino acid sequence given in first source; a hlh protein of the enhancer of split locus complex, e(spl)-c; refseq nm_079780
E-1 styrylpyridine-crown ether: an e-4-styrylpyridine derivative with 18-crown-6 as a substituent
E-3,4-bis(4-ethylphenyl)hex-3-ene: synthetic stilbene derivative
E-4-(6'-hydroxyhex-3'-en-1-yl)phenylpropionate: an inhibitor of aldose reductase from ocimum basilicum
E-5-iodomethylene-6,6-dimethyl-5,6-dihydropyran-2-one: antineoplastic
E-7386: inhibitor of the interaction between beta-catenin and creb binding protein
E-Syt1 protein, mouse: a 5 c2 domain membrane protein; has been sequenced
E-Syt2 protein, mouse: an extended synaptotagmin-like protein; has been sequenced
E-Z Gold: a direct filling gold material similar to existing powdered gold formulations but more user-friendly; a mixture of gold powder & wax
E-glycoprotein, Dengue virus type 2: mw 53-55 kd; major glycoprotein in lipid envelope; monoclonal antibodies against den e-gp protect mice against dengue infection
E-octadec-7-en-5-ynoic acid: from the roots of capparis zeylanica
E-omega-benzoyloxyferulenol: from the sardinian giant fennel (ferula communis)
E-onjisaponin H: isolated from the root of polygala tenuifolia willd
E-prostanoid 3 receptor, zebrafish: refseq xm_017356646.1
E021: peptide solution which affects passive avoidance behavior in young rats when administered in first few days after birth; amino acid sequence known
E1 envelope protein, Rubella virus: 481 amino acid residues given in first source; has potential as a diagnostic & immunizing antigen
E1 protein, Bovine papillomavirus: involved in dna replication; amino acid sequence known
E1 protein, Human papillomavirus type 11: essential for dna replication; amino acid sequence known
E1 protein, Human papillomavirus type 31: expressed during amplification of the hpv genome; has been sequenced
E1 protein, Human papillomavirus type 6: human pathogens that cause epithelial hyperproliferative lesions
E1 protein, human papillomavirus type 1: e1 and e2 proteins encoded by human cutaneous papillomaviruses are required for viral dna replication; amino acid sequence known
E1-INT: an injectable islet neogenesis therapy comprising an epidermal growth factor analog and a gastrin analog, for the treatment of insulin-dependent (type 1) and non-insulin-dependent (type 2) diabetes; hypoglycemic agents
E10 protein, Equid herpesvirus 2: activates nf-kappab transcription factor and c-jun n-terminal kinase; has a caspase-recruiting domain (card); amino acid
E10030 aptamer: a 32-mer pegylated dna aptamer that is an antagonist of platelet-derived growth factor
E1231: piperazine 1,4-diamide compound; sirt1 activator
E1A protein 243R, Human adenovirus type 5: one of the two major proteins produced by the e1a region of adenovirus type 5; 243 amino acid residues; amino acid sequence has been determined
E1B55K protein, adenovirus: plays a role in radiosensitization, by targeting the mre11, rad50, and nbs1 complex (mrn) and inhibiting dna double-strand break (dsb) repair
E1E2 peptide: consisting of two self-replicating peptides that catalyse each other's production; amino acid
E1K2 peptide: consisting of two self-replicating peptides that catalyse each other's production; amino acid
E2 envelope protein, Rubella virus: 282 amino acid residues given in first source
E2 protein, Cottontail rabbit papillomavirus: low levels stimulate transactivation
E2 protein, Human papillomavirus type 16: base sequence data given in first source
E2 protein, Human papillomavirus type 31: amino acid sequence of the dna-binding domain given in first source
E2 protein, Ross River virus: nucleocapsid-glycoprotein interactions of two viruses, ross river & sindbis viruses are required for assembly of alpha viruses; amino acid sequence has been determined
E2A-Pbx1 fusion protein: product of a chimeric homeobox oncogene formed by the t(1;19) translocation in human pre-b cell acute lymphoblastic leukemia (all); has 2 isoforms, p85 (a) & p77 (b); amino acid sequence has been determined; rn refers to isoform a
E2F6 protein, human: member of the e2f family that can behave as a transcriptional repressor; refseq nm_001952
E2Fa protein, Arabidopsis: affects expression of both positive and negative regulators of cell division and growth; genbank aj294534
E2L2 protein, Arabidopsis: e2f-like repressor of arabidopsis that bind to e2f sites in a monomeric form; genbank ab074532
E2a-Hlf fusion protein, human: hlf, a hepatic bzip protein showed altered dna-binding properties following fusion to e2a in acute lymphoblastic leukemia; amino acid sequence given in first source
E2a-Hlf fusion protein, mouse: hlf, a hepatic bzip protein showed altered dna-binding properties following fusion to e2a in acute lymphoblastic leukemia; amino acid sequence given in first source
E2f1 protein, Drosophila: is likely to be the mediator of hypoxia-induced arrest at metaphase and pre-s phase; refseq nm_079713
E2f2 protein, Drosophila: homologous to mammalian e2f transcription factors; genbank ab016824
E2f3 protein, mouse: member of e2f family; refseq xm_127250
E2f5 protein, mouse: a member of the e2f family; refseq nm_007892
E2f5 protein, rat: a member of the e2f family; refseq xm_342209
E2f7 protein, mouse: appears to block cellular proliferation; refseq nm_178609
E3 glycoprotein 19k, Adenovirus type 7: a human adenovirus protein isolated from 17 clinical isolates; amino acid sequence given in first source
E3 protein, Bacteriophage SPO1: causes inhibition of dna, rna, and transcription in bacillus subtilis; has been sequenced
E3 ubiquitin ligase RNF157, mouse: refseq nm_027258
E3 ubiquitin-protein ligase rnf213-alpha, zebrafish: mutation causes abnormal angiogenesis and circulation defects; refseq xm_009299818
E3-13.7 protein, human adenovirus: encoded by human adenoviruses; diverts recycling egf receptors to lysosomes; has been sequenced
E3-20.5K membrane protein, Adenovirus: has an overall similarity to gp19k protein; a membrane protein that is glycosylated and has a short cytoplasmic tail; amino acid sequence given in first source
E3-3 protein, rat: a ubiquitously expressed protein from rat; has many isoforms, mw 12-21 kda; amino acid sequence given in first source
E3-6.7K protein, Adenovirus: a type iii integral membrane protein; amino acid
E3030 compound: a dual peroxisome proliferator-activated receptor alpha/gamma agonist with antidiabetic and hypolipidemic effects
E3A protein, Human adenovirus 19a: an hla-binding protein distinct from that of subgroups b & c; genbank x95259
E3L protein, Ectromelia virus: is a dsrna-binding proein with a conserved c-terminal dsrna-binding domain; amino acid
E3L protein, Vaccinia virus: a double-stranded rna binding proteins that inhibits protein kinase; has been sequenced
E3L protein, orf virus: 31% identical to vaccinia virus e3l protein; amino acid
E4 protein, Adenovirus 9: from human adenovirus type 9; requires e4 region transforming protein for oncogenicity; amino acid sequence given in first source
E4 protein, Human papillomavirus type 6: present in condylomata acuminatum of hpv-6 infected patients
E4 protein, Lycopersicon esculentum: amino acid sequence given in first source; involved in fruit ripening
E474 peptide: a synthetic peptide derived from the mouse mammary tumor virus envelope protein; induces anti-tumor immunity
E4G10 antibody: an anti-vascular endothelial-cadherin antibody
E4TF1 transcription factor: amino acid sequences of e4tf1 subunits, e4tf1-47, e4tf1-53, and e4tf1-60, given in first source; regulates transcription from the adenovirus e4 promoter
E4orf3 protein, adenovirus: increases killing of cancer cells by radiotherapy in vivo
E4orf6 protein, adenovirus: increases killing of cancer cells by radiotherapy in vivo
E5 CXCR4-targeting peptide: a synthetic peptide targeting cxcr4
E5 protein, Human papillomavirus type 31: supports cell cycle progression and activates late viral functions upon epithelial differentiation; has been sequenced
E5 protein, Human papillomavirus type 6: e5 proteins of hpv, type 6 and 11 share several structural similarities with the bovine papillomavirus type 1 e5; aa sequence known
E5 protein, cottontail rabbit papillomavirus: a mitogenic protein; amino acid
E587 protein, Carassius auratus: an exonal recognition molecule expessed in the goldfish central nervous system; genbank u55211
E5A protein, Human papillomavirus type 11: etiological agent of condyloma acuminata & respiratory papillomata; encoded by a transforming oncogene; 91 amino acids; partial amino acid
E5B protein, bovine papillomavirus 1: amino acid ; a hydrophobic protein involved in altering host-cell protein processing
E5R protein, Vaccinia virus: mw 45 kda; amino acid sequence known
E6 protein, Human papillomavirus type 18: mw 18kda polypeptide found in cells derived from human cervical carcinomas
E6 protein, Human papillomavirus type 6: human pathogens that cause epithelial hyperproliferative lesions
E6 protein, Old World harvest mouse papillomavirus: has been sequenced; identified in micromys minutus papillomavirus and mastomys natalensis papillomavirus; partial amino acid sequence given in first source
E6-target protein 1: a gap (gtpase-activating protein) protein that binds eb oncoproteins; amino acid ; genbank af090989
E6DG1 protein, mouse: may function in a signaling pathway related to anchorage-independent growth and adhesion control; 45 amino acid residues, mw 7 kda; amino acid
E7 protein, Bovine papillomavirus type 4: a major transforming protein of bvp-4; amino acid
E7 protein, Human papillomavirus type 18: nucleotide sequence given in first source
E7 protein, Human papillomavirus type 33: human papillomavirus type 33 e7; has been sequenced
E7 protein, cottontail rabbit papillomavirus: involved in virus-mediated induction of papillomas; e7 protein has both transforming and trans-activating activities; has been sequenced
E75 protein, insect: an ecdysteroid-induced e75 gene product of wax moth, galleria mellonella; member of the steroid hormone receptor superfamily; gme75a & b are isoforms; amino acid sequence given in first source; genbank u02620 (gme75a)
E7777 fusion protein: denileukin diftitox with improved purity , increased percentage of active protein monomer species, and reduced level of misfolded and/or aggregated protein impurities
E8 protein, Bovine papillomavirus: contributes to transformation of primary bovine cells (palfs) by inducing anchorage-independent growth and by down-regulating gap junction intercellular communication, likely due to its binding to 16k ductin
E8 protein, Lycopersicon esculentum: an ethylene-responsive fruit ripening protein; from tomato; structurally related to 1-aminocyclopropane-1-carboxylate (acc) oxidase and to 2-oxoglutarate-dependent dioxygenases; amino acid sequence given in first source
E8 protein, cottontail rabbit papillomavirus: a mitogenic protein; amino acid sequence known
E8R protein, Vaccinia virus: a vaccinia virus protein involved in endoplasmic reticulum membrane wrapping required for viral dna replication; amino acid
E9 protein, papillomavirus: a transforming protein from different animal papillomaviruses; partial amino acid sequence given in first source; rn refers to reindeer e9 protein
E9730 protein, human: named e9730 = a clone number of fetal liver cdna; enhances ap-1 activity through interacting with jab1 (jun-activating domain binding protein 1); has been sequenced
EA 575 extract: anti-inflammatory from hedera; decreases lps-induced il-6 release from murine macrophages
EA-4 (ATRA steroidal analog): all-trans retinoic acid (atra) analog
EAA-090: a potent n-methyl-d-aspartate antagonist
EAB 309: eab-309 is more active than its enantiomer eab-310
EAF1 protein, human: an ell-associated factor that is delocalized by expression of the mll-ell fusion protein; refseq nm_033083
EAF2 protein, Xenopus: part of the ell-mediated rna polymerase ii elongation factor complex; involved in eye development; genbank aj579576
EAFP2 peptide, Eucommia ulmoides: the tertiary structure of eafp2 represents the first five-disulfide cross-linked structural model of the plant antifungal peptide; adopts a compact global fold composed of a 3(10) helix (cys3-arg6), an alpha-helix (gly26-cys30), and a three-strand antiparallel beta-sheet (cys16-ser18, tyr22-gly24, and arg36-cys37); shows a chitin-binding domain (residues 11-30) with a hydrophobic face and a characteristic sector formed by the n-terminal 10 residues and the c-terminal segment cross-linked through the unique disulfide bond cys7-cys37, which brings all four positively charged residues (arg6, arg9, arg36, and arg40) onto a cationic face; amino acid
EAK16 peptide: an ionic self-complementary peptide capable of forming a membranous matrix
EAP45 protein, mouse: a component of the escrt-ii complex; genbank bc010811
EAP45 protein, rat: ell-associated protein of approximately 45 (eap45) kda; amino acid ; nm_001106092
EAPP protein, mouse: modulates e2f-regulated transcription, stimulates proliferation, and may be involved in the malignant transformation of cells; genbank ay882557
EAR1 protein, S cerevisiae: an rsp5 adaptor; has been sequenced
EAR2 protein, Gallus gallus: a v-erb a related protein from chicken; has been sequenced
EARLI1 protein, Arabidopsis: a vernalization-responsive gene in arabidopsis thaliana; amino acid
EAST protein, Drosophila: an egf receptor- & eps15-associated protein; has src homology 3 & tyrosine-based activation motif domains; mw 52 kda; amino acid
EAST protein, human: an egf receptor- & eps15-associated protein; has src homology 3 & tyrosine-based activation motif domains; mw 52 kda; amino acid
EAT1 protein, S cerevisiae: refseq nm_001181144.1
EAV nucleocapsid protein, Equine arteritis virus: a nucleocapsid protein of equin arteritis virus; has been sequenced
EB1 microtubule binding proteins: associates with apc protein from colorectal cancer; amino acid ; genbank u24166
EB1 protein, Botryllus schlosseri: a tunicate homolog of human eb1; from botryllus schlosseri; 48% identical to human eb1; has 287 amino acid residues; amino acid sequence given in first source; genbank x99321
EB1c protein, Arabidopsis: a microtubule plus-end tracking protein
EB3 protein, mouse: a microtubule plus-end binding protein that interacts with dda3; genbank af468005
EBA-175II F2 protein, Plasmodium falciparum: binds glycophorin a
EBA140 protein, Plasmodium falciparum: binds a sialic acid-containing receptor on human red blood cells; isolated from plasmodium falciparum; amino acid
EBAG9 protein, human: srcas1 is the soluble form; refseq nm_004215
EBAG9 protein, rat: binds snapin and decreases its phosphoryation; involved in vesicle exocytosis; genbank bc087093
EBC-304: has antineoplastic activity; isolated from the australian rainforest plant croton insularis
EBC-320: has antineoplastic activity; isolated from the australian rainforest plant croton insularis
EBC-46: a protein kinase c activator with antineoplastic activity; isolated from fontainea picrosperma
EBF3 protein, Xenopus: may be involved in neuronal differentiation; similar to ebf/olf-1 proteins; amino acid
EBI-005: interleukin-1 inhibitor; a protein chimera of il-1(beta) and il-1 receptor antagonist (il-1ra)
EBI3 protein, rat: forms a heterodimer with p28; has been sequenced; refseq nm_001109421
EBNA-2 protein (338-358), citrullinated-: a citrullinated peptide used to detect anti-citrullinated protein-peptide antibodies in immunoenzymatic assays
EBNA-2 protein, Human herpesvirus 4: isolated from epstein-barr virus
EBNA-5 protein, Epstein-Barr virus: binds retinoblastoma and p53 proteins; amino acid
EBNA-LP protein, Human herpesvirus 4: isolated from epstein-barr virus; amino acid
EBP protein, human: from endoplasmic reticulum; mutations are known to cause chondrodysplasia punctata; refseq nm_006579
EBP1 protein, Entamoeba histolytica: genbank af224345
EBP2 protein, Entamoeba histolytica: dna-binding protein that recognizes the upstream regulatory element ure4; genbank af224346
EBS adhesive system: an etchant, primer & adhesive; contains 32% phosphoric acid, hydroxyethylmethacrylate, methacryl-magnesium chelate, water, bis-methacrylates & malonic acid-alkyl-methacrylate
EBS protein, Arabidopsis: may be part of a repressor complex that modulates chromatin structure; genbank n96619 and t46081
EBV-BART10-3p microRNA: ebv- epstein-barr virus encoded mirna involved in nasopharyngeal carcinoma development
EBV-associated membrane antigen, Epstein-Barr virus: do not confuse with lmp-2 protein which is a class ii mhc protein also written as lmp2; d1lmp lacks amino terminus & first four transmembrane domains; mediates latent virus infection or b-lymphocyte proliferation; amino acid sequence has been determined
EC-7012: indolocarbazole analog that have demonstrated a robust ability to inhibit a wide range of pro-survival kinases
EC0225: a folate-targeted dual drug conjugate with antitumor activity; basically consists of subparts: folic acid; the hydrophilic peptide spacer, asp-asp-asp-βdpr-cys; the vinca alkaloid drug moiety, davlbh; the dna alkylating drug moiety, n7-mercaptoethyl-mitomycin c (n7-me-mmc)
EC131 conjugate: folate receptor-targeted drug conjugate prepared by covalently attaching the vitamin folic acid to a potent microtubule-inhibiting agent, maytansinoid dm1, via an intramolecular disulfide bond; has folate receptor-specific antitumor activity
EC145: has significant antiproliferative activity and tolerability, thus lending support to an ongoing phase 1 trial for the treatment of advanced malignancies
EC3 protein, Echis carinatus: ec3a and ec3b are subunits of ec3; an alpha4 integrin antagonist isolated from echis carinatus venom; amino acid
EC6 protein, Echis carinatus sochureki: a heterodimeric disintegrin that inhibits alpha9beta1-mediated adhesion to vcam-1; also inhibits neutrophil migration across endothelial cells activated by tumor necrosis factor; isolated from e. carinatus venom; amino acid
ECAT11 protein, mouse: expressed in embryonic stem cells; refseq nm_001081202
ECB2 protein, Arabidopsis: a pentatricopeptide repeat protein involved in chloroplast development; refseq nm_101420
ECE1 protein, Candida albicans: expressed in association with cell elongation of a dimorphic pathogen, candida albicans; ece - extent of cell elongation; amino acid sequence given in first source; genbank l17087
ECH2 protein, Arabidopsis: a peroxisomal enzyme involved in degradation of even cis-unsaturated fatty acids; amino acid
ECI protein, Erythrina variegata: from the seeds of erythrina variegata; amino acid sequence given in first source
ECI-6 protein, Sus scrofa: inhibitor of nf-kappa b in porcine aortic endothelial cells; amino acid sequence given in first source; genbank z21968
ECM27 protein, S cerevisiae: refseq nm_001181764.4
ECM3 protein, Lytechinus variegatus: contains ng2-like and multiple calcium-binding domains; amino acid ; genbank af287478
ECM32 protein, S cerevisiae: a dna-dependent atpase/dna helicase; mw 129 kda; genbank u18922
ECM33 protein, S cerevisiae: important for proper cell wall ultrastructure organization and, for the correct assembly of the mannoprotein outer layer of the cell wall
ECP1 protein, Cladosporium fulvum: from cladosporium fulvum; amino acid sequence given in first source; genbank z14023; a biotrophic pathogen of tomato
ECP2 protein, Cladosporium fulvum: from cladosporium fulvum; amino acid sequence given in first source; genbank z14024; plays a role in plant pathogenesis
ECP31 protein, Daucus carota: amino acid sequence given in first source; mr 31,000; an embryogenic-cell protein from carrot, daucus carota l
ECP4 protein, Cladosporium fulvum: isolated from cladosporium fulvum; amino acid ; genbank aj271890
ECP5 protein, Cladosporium fulvum: amino acid ; genbank aj271891
ECR1 protein, Arabidopsis: related to c-terminus of the e1 ubiquitin-activating enzyme; isolated from arabidopsis thaliana; amino acid ; genbank af051135
ECT1 protein, Arabidopsis: may be involved in relaying calcium signals to nucleus; genbank ay894117
ECT2 protein, Arabidopsis: may be involved in relaying calcium signals to nucleus; genbank ay894118
ECT2 protein, human: ect - epithelial cell transforming; the central core has significant homology with the bcr, cdc24 & dbl proteins; refseq nm_018098
ECU-01 cpd: a poorly water-soluble drug ecu-01, a low molecular enzyme-inhibitor with anti-inflammatory properties
ECa 233 extract: a standardized extract of centella asiatica with neuroprotective effects
ECaC protein, Oryctolagus cuniculus: an apical calcium influx channel; genbank aj133128
ED protein, Drosophila: cell adhesion molecule echinoid defines a new pathway that antagonizes the drosophila egf receptor signaling pathway; amino acid ; refseq nm_078745
EDC3 protein, mouse: a p-body protein involved in regulation of removal of mrna 5' cap structure; refseq nm_153799
EDC34 peptide: a c-terminal fragment of tissue factor pathway inhibitor-2 (tfpi-2) with antibacterial activity
EDEM2 protein, human: a stress-induced mannosidase-like protein that localizes to the er lumen; refseq nm_018217
EDEN-specific RNA-binding protein, Xenopus: 50% identical to bruno protein from drosophila; mediates sequence-specific mrna deadenylation; isolated from xenopus; amino acid ; genbank af003923
EDF1 protein, human: homologous to mbf1 protein from silkworm; down-regulated during endothelial cell differentiation; refseq nm_003792
EDI3 protein, mouse: catalyzes the hydrolysis of glycerophosphocholine to glycerol-3-phosphate and choline
EDIL3 protein, Xenopus: induces aggregation of melanosomes; genbank ay491055
EDIL3 protein, human: binds alphavbeta3 integrin; contains three egf-like repeats; refseq nm_005711
EDNsFv anti-transferrin receptor: human recombinant eosinophil-derived neurotoxin fused to sfv, a single chain antibody; amino acid sequence known
EDR2 protein, Arabidopsis: negatively regulates both the defense response against powdery mildew and cell death; refseq nm_118022
EDS1 protein, Arabidopsis: an essential component of r gene-mediated disease resistance in arabidopsis has homology to eukaryotic lipases; amino acid
EDS5 protein, Arabidopsis: involved in salicylic acid-dependent signaling for disease resistance; a member of the mate transporter family; genbank af416569
EDTA monooxygenase: oxidizes edta to glyoxylate and ethylenediaminetriacetate, the first step of edta degradation by bacterium bnc1; mw 45 kda; amino acid sequence known
EDTA-cystine copolymer: fails to enhance clearance of intracellularly incorporated plutonium
EE 581: photosensitive azido derivative of tyrosine(3)-octreotide used to label the somatostatin receptor; amino acid sequence given in first source
EED protein, Drosophila: a polycomb protein involved in the propagation of repressive histone marks
EEF1AKNMT protein, human: feat - faint expression in normal tissues, aberrant overexpression in tumours; refseq nm_014955
EEF2KMT protein, human: lysine-specific methyltransferase, refseq nm_201400
EEL-1 protein, C elegans: a hect e3 ubiquitin ligase that controls asymmetry and persistence of the skn-1 transcription factor in the early c. elegans embryo; has been sequenced; refseq nm_067883
EER4 protein, Arabidopsis: localized to the nucleus where it probably recruits ein3 and probably other transcription factors along with components of the tfiid complex for expression of a subset of genes required for either manifestation or subsequent dampening of the response to ethylene; amino acid
EET-B: epoxyeicosatrienoic acid analog eet-b
EF 7412: a 5-ht(1a)/d(2) antagonist
EF protein, Pseudaletia separata entomopoxvirus: an enhancing factor from the armyworm pseudaletia separata; amino acid ; genbank d50590
EF0377 protein, Enterococcus faecalis: genbank ae016948
EF1 protein, Rous sarcoma virus: 75% identical to rat ef1; amino acid sequence given in first source; genbank l20500
EF5154: a potent glycoprotein iib/iiia receptor antagonist
EFA-6 protein, C elegans: efa - exchange factor for arf family member; refseq np_502416
EFEMP2 protein, human: 443 amino acid residues; amino acid ; refseq nm_016938
EFF1009: a medical food that decreases leukotriene b(4) synthesis
EFG1 protein, Candida albicans: regulator of candida morphogenesis; involved in the control of white-opaque phenotype; has been sequenced
EFH5 protein, Trypanosoma brucei: amino acid sequence given in first source; 192 amino acid residues; a new member of ef-hand superfamily; closely related to lav1-2 from physarum; from trypanosoma brucei
EFHC1 protein, Xenopus: refseq nm_001092940
EFHC1 protein, human: mutations in efhc1 cause juvenile myoclonic epilepsy; refseq nm_018100
EFK17 peptide: synthetic peptide sequence with antimicrobial properties derived from ll-37
EFLA 85942: green tea extract is able to induce specifically the neutral endopeptidase (nep) activity and to inhibit the proliferation of sk-n-sh cells
EFNA1 protein, Xenopus: member of the eph ligand family (elf); a 28 kda secreted protein from xenopus; amino acid sequence given in first source
EFNB1 protein, Xenopus: xlerk - xenopus ligand for eph receptor tyrosine kinases; homologue of the murine lerk-2 (ephrin-b1); an eph ligand involved in mesoderm induction & neurogenesis; amino acid sequence given in first source; genbank u31427
EFNB1 protein, human: putative ligand for receptor tyrosine kinase elk; refseq nm_004429
EFO1 protein, Arabidopsis: a wd domain protein; refseq nm_124604
EFO2 protein, Arabidopsis: a wd domain protein; refseq nm_122278
EFR3 protein, S cerevisiae: required for assembly of the stt4 complex; genbank z49809
EFS protein, human: efs - embryonal fyn-associated substrate; contains a src homology 3 domain; refseq nm_005864
EFsec protein, mouse: required for recoding of uga from a stop codon to one for selenocysteine; genbank af268871
EG95 protein, Echinococcus granulosus: a host protective vaccine antigen for hydatid disease; has been sequenced
EGF-IL-18 fusion protein, mouse: egf (egf homologous polypeptide vaccinia virus growth factor)-il-18 recombinant fusion protein caused regression of experimental neoplasms which was associated with g1 arrest and induction of apoptosis
EGF-SCI protein, human: synthetic protein consisting of insulin precursor (b chain(1-29)-a chain) linked to c-terminal lysine of egf(1-28)
EGF-genistein: an egfr-binding cytotoxic agent; inhibits egfr tyrosine kinase and other ptks associated with egfr
EGFL9 protein, mouse: adipogenesis may be modulated by the coordinated expression of dlk1 and dlk2 protein
EGFR protein, Anopheles gambiae: ager - egfr ortholog from anopheles; from the malaria mosquito anopheles gambiae: orthologs from drosophila, human, mouse & chicken; genbank, aj301655 and aj304406
EGFR-lytic peptide: a 32-mer peptide that consists of both egfr-binding and lytic sequences
EGG-4 protein, C elegans: a pseudotyrosine phosphatase; refseq nm_058868
EGG-5 protein, C elegans: a pseudotyrosine phosphatase; refseq nm_058915
EGL-1 protein, C elegans: cell death activator from caenorhabditis elegans; genbank af057309
EGL-10 protein, C elegans: member of the rgs (regulators of g protein signaling) family; involved in control of egg-laying behavior in c. elegans; amino acid sequence given in first source; genbank u32326; a protein isolated from caenorhabditis elegans
EGL-13 protein, C elegans: a sox domain transcription factor that affects the uterine pi cell lineages; has been sequenced
EGL-15 protein, C elegans: isolated from caenorhabditis elegans
EGL-27 protein, C elegans: controls cell polarity and cell migration in c. elegans; encodes a homolog of human mta1, part of an atp-dependent complex with nucleosome remodelling and histone deacetylation activities that may promote tumor metastasis; in conjunction with its paralog egr-1, egl-27 is required for proper organization in all parts of the embryo, and for the embryonic expression of hlh-8; amino acid ; genbank af096618
EGL-3 proprotein convertase, C elegans: egl stands for egg-laying defective mutant; refseq nm_073213
EGL-4 protein, C elegans: regulates the olfactory adaptation; has been sequenced
EGL-46 protein, C elegans: the sensory function of hob neuron requires the combined action of the egl-46 and daf-19 regulatory pathways; np_504694
EGL-II glycosphingolipid: a triphosphonooctaosylceramide from the eggs of the sea hare, aplysia kurodai
EGL4 protein, Hypocrea jecorina: from trichoderma reesei; has endoglucanase activity; amino acid ; genbank y11113
EGO-1 protein, C elegans: related to rna-directed rna polymerase and functions in germ-line development and rna interference in c. elegans; amino acid
EGP314 antigen: human epithelial glycoprotein antigen; amino acid
EGR1 protein, Xenopus: similar to krox-20 protein; xenopus laevis protein expressed in the spemann organizer region; homologous protein found in mammals
EGRH-1 protein, C elegans: an early growth response factor family member; refseq nm_078061
EGT2 protein, S cerevisiae: involved in cell separation in the g1 phase of cell cycle
EGX, Ampullaria crossean: a multi-functional cellulase from the stomach juice of mollusca, ampullaria crossean
EH-1 protein, Tobacco mosaic virus: prepared from tobacco mosaic virus (tmv)-infected tobacco leaves; amino acid ; genbank u57350
EH-1501: hepatoprotectant, composition:23 mg grape leaf, 23 mg wild strawberry, 2 mg dandelion, 1 mg milk thistle, 49 mg fiber; contains small amount of silymarin
EH0202: clinically improved menopausal symptoms in post-menopausal women & appears to help maintain normal biological function and improves quality of life; contains a proprietary blend of four herbs & bifidobacterium longum
EHBP-1 protein, C elegans: involved in recruitment of rab-10 to the membrane; refseq nm_073067
EHBP1 protein, human: an eh domain binding protein involved in coupling endocytosis with the actin cytoskeleton; refseq nm_015252
EHBP1L1 protein, human: forms a complex with rab8 and bin1; involved in apical-directed transport in epithelial cells
EHBP1L1 protein, mouse: forms a complex with rab8 and bin1; involved in apical-direct transport in epithelial cells
EHD protein-binding protein 1, Drosophila: refseq nm_001144211
EHD2 protein, human: an eh domain protein; refseq nm_014601
EHD2 protein, mouse: ehd2 and the eh domain binding protein ehbp1 couple endocytosis to the actin cytoskeleton; refseq nm_153068
EHD2 protein, rat: interacts with glut4; genbank af494093
EHD2-binding protein 1, mouse: an eh domain binding protein involved in coupling endocytosis with the actin cytoskeleton; amino acid
EHD3 protein, human: ehd3 localizes on endocytic tubular and vesicular structures and regulates their microtubule-dependent movement; from the glioma tumor suppressor candidate region; an eh domain protein; refseq nm_014600
EHEC-hlyA protein, E coli: an rtx (repeats in toxin) toxin; has been sequenced
EHK1 ligand: a ligand for ehk1, an eph-related kinase; amino acid sequence given in first source
EHMT2 protein, human: ng36/g9a gene products are encoded within the human and mouse mhc class iii regions; refseq nm_006709
EHN-3 protein, C elegans: tra-1/gli and ehn-3 have overlapping roles in regulation of multiple steps of sgp development
EHT 4063: an eht-1864 analog that lacks the inhibitory activity against rac1 signaling
EI 1507-1: interleukin-1beta converting enzyme inhibitor isolated from streptomyces
EI 1507-2: interleukin-1beta converting enzyme inhibitor isolated from streptomyces
EI 1511-3: inhibits interleukin-1beta converting enzyme; isolated from streptomyces
EI 1511-5: inhibits interleukin-1beta converting enzyme; isolated from streptomyces
EI 1625-2: inhibits interleukin-1beta converting enzyme; isolated from streptomyces
EI-2346: an interleukin-1beta converting enzyme inhibitor from streptomyces sp.
EI24 protein, human: a p53 response gene involved in growth suppression and apoptosis; refseq nm_004879
EI24 protein, mouse: confers resistance to etoposide; has been sequenced
EIAP protein, Xenopus: a survivin-related protein; has been sequenced
EID-2 protein, mouse: inhibits transactivation by myod; genbank ay251273
EID1 protein, Arabidopsis: an f-box protein involved in phytochrome a-specific light signaling; a repressor component in the phya-dependent hir-signaling pathway; amino acid
EIF4E2 protein, human: binds capped rna; refseq nm_004846
EIF4ENIF1 protein, human: mediates transport of eif4e into nucleus; refseq nm_019843
EIF4G2 protein, human: homologous to eif-4g and eif-(iso)4f; refseq nm_001418
EIL3 protein, Arabidopsis: ein -ethylene-insensitive; amino acid ; databank pdb/1d1wij
EIN protein, E coli: 30-kda domain of phosphoenolpyruvate-protein phosphotransferase
EIN2 protein, Arabidopsis: a bifunctional transducer of ethylene & stress response in arabidopsis; amino acid ; genbank af141202
EIN3 protein, Arabidopsis: activates ethylene gas response pathway; required for ethylene responsiveness in adult plant tissues; binds a primary ethylene response element present in the ethylene-response-factor1 promoter with consequence to activate the transcription of this gene; genbank af004217 and af004216
EIN4 protein, Arabidopsis: member of the ethylene receptor gene family in arabidopsis; amino acid
EIP1 protein, Arabidopsis: a wnk (with-no-lysine) kinase involved in regulating flowering time
EIPR-1 protein, C elegans: a wd40 protein; refseq nm_060982.4
EIPW 103: derivatives of clomiphene; non-steroidal antifertility agents; rn given refers to parent cpd
EL 241: rn given refers to parent compound; presence in urine characteristic of aspartylgluucosaminuria
EL35 protein, human: chromogranin a-derived peptide in the human pituitary; may play a role as autocrine, paracrine, or endocrine regulatory peptides; amino acid
EL35 protein, rat: chromogranin a-derived peptide in the rat pituitary; amino acid
ELAC1 protein, human: may be involved in lung carcinogenesis; refseq nm_018696
ELAC2 protein, human: a prostate cancer susceptibility gene product that may encode a hydrolase; refseq nm_018127
ELD1 protein, Arabidopsis: a serine-rich secreted protein; amino acid
ELF1 protein, Eucalyptus globulus: functionally equivalent to leafy protein from arabidopsis; amino acid ; genbank af034806
ELF3 protein, Arabidopsis: regulates circadian clock function and flowering in arabidopsis; amino acid
ELF4 protein, Arabidopsis: affects flowering time; genbank ay035183
ELF5 protein, Arabidopsis: a floral repressor; genbank ay526094
ELF5 protein, human: an ets family member; expressed in glandular epithelium and differentiated keratinocytes; alternative splicing produces two isoforms; refseq nm_198381
ELIP2 protein, Arabidopsis: a high-light-inducible elip2 gene
ELL protein, Xenopus: involved in the inhibition of canonical wnt signaling pathway in cytoplasm; amino acid
ELL2 protein, Xenopus: involved in the inhibition of canonical wnt signaling pathway in cytoplasm; amino acid
ELL3 protein, human: a testis-specific rna polymerase ii elongation factor; refseq nm_025165
ELMO1 protein, rat: leads to increased expression of extracellular matrix proteins; has been sequenced
ELMO2 protein, human: required for phagocytosis and cell migration; binds ced-5/dock180 to affect rac1 activity; refseq nm_022086
ELMOD2 protein, human: may be involved in familial idiopathic pulmonary fibrosis; refseq nm_153702
ELO-5 protein, C elegans: a long-chain fatty acid elongase; genbank nm_068392
ELO-6 protein, C elegans: a long-chain fatty acid elongase; genbank nm_068396
ELO1 protein, Arabidopsis: a homolog of elongator subunit elp4; genbank aj964957
ELP protein, Arabidopsis: atelp - arabidopsis thaliana epidermal growth factor receptor-like protein; amino acid sequence given in first source; genbank u86700
ELP-1 protein, C elegans: required for touch sensation; genbank z92833
ELP3 protein, Drosophila: an rna polymerase ii component; genbank ak012072
ELP3 protein, zebrafish: an rna polymerase ii component; genbank bc096810
ELPEC20: an elp (elastin-like polypeptide) biopolymer containing synthetic phytochelatin (ec) as the metal-binding domain for ex situ soil washing
ELS1 MATE transporter, Arabidopsis: do not confuse with at3g06910, which is also known as els1
ELT-1 protein, C elegans: a caenorhabditis elegans gata transcription factor; has been sequenced
ELY-2 antigen, horse: polymorphic locus of horse first detected 55 days after conception in serum of pregnant mare; suggests that source may be tissue of equine endometrial cups
ELYS protein, mouse: expressed predominantly in mouse foetal haematopoietic tissue; amino acid
EM 800: em-800 is the prodrug of em-652; em-800 and em-776 are (s)- and (r)-isomers, respectively
EM011 compound: an antimicrotubule agent and tubulin-binding agent with significant anticancer activity
EM012 alkaloid: antineoplastic semisynthetic phthalideisoquinoline alkaloid
EM23 sesquiterpene: antineoplastic isolated from elephantopus mollis
EM5 protein, Ensis minor: a mulluskan (ensis minor) major sperm protein; histone h1 homolog; 150 amino acid residues; amino acid sequence has been determined
EM6 protein, Ensis minor: a mulluskan (ensis minor) major sperm protein; 270 amino acid residues; amino acid sequence has been determined
EM66 peptide: a 66-amino acid peptide from the proleoytic processsing of secretogranin ii; circulating em66 is a highly sensitive marker for the diagnosis and follow-up of pheochromocytoma
EM95 protein, Echinococcus multilocularis: can be used to induce significant levels of protection against challenge infection with e multilocularis eggs in mice; genbank ay062920-1
EMA-1 protein, Babesia equi: homologous to theileria piroplasm surface proteins; isolated from babesia equi; amino acid sequence given in first source; genbank l13784
EMA-2 protein, Babesia equi: isolated from babesia equi; amino acid ; genbank u97166 and u97169
EMA400: ema400 and ema 401 are (r)- and (s)-enantiomers, respectively; an angiotensin ii type 2 receptor antagonist with analgesic activity
EMAP protein, Strongylocentrotus purpuratus: may modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic; genbank u15551
EMB protein, human: an mct2 chaperone; refseq nm_198449
EMB-1 protein, Daucus carota: involved early in somatic embryogenesis; from carrot, daucus carota; has homology to wheat em protein; amino acid sequence given in first source
EMB1303 protein, Arabidopsis: localized to chloroplasts; refseq nm_104499
EMB175 protein, Arabidopsis: 896 amino acid residues pentatricopeptide repeat (ppr) protein involved in embryogenesis; amino acid
EMB2473 protein, Arabidopsis: emb2473/miro1 is a miro gtpase required for embryogenesis and influences mitochondrial morphology in pollen; refseq nm_122636
EMB2654 protein, Arabidopsis: a pentatricopeptide repeat protein
EMB3143 protein, Arabidopsis: refseq nm_125210.5
EMB506 protein, Arabidopsis: an ankyrin repeat protein isolated from arabidopsis; required for development of embryos; genbank af026167
EMCN protein, human: an anti-adhesive protein; refseq nm_016242
EMD 281014: highly selective 5-hydroxytryptamine (5-ht)(2a) receptor antagonist
EMD 29645: n1 same as sy #1; structure in 2nd source
EMD 29946: n1 same as sy #1; structure in 2nd source
EMD 486019: antitumor sulfamate; ; in phase ii clinical trial 6/2008
EMD 521873: a fusion protein consisting of modified human il-2 which binds specifically to the high-affinity il-2 receptor, and an antibody specific for both single- and double-stranded dna, designed to facilitate the enrichment of il-2 in tumor tissue
EMD 53998: emd 53998 is racemic; emd 57439 is the (-)-isomer; emd 57033 is the (+)-isomer
EMD 55450: ; analog of emd 55068 with terminal amino group blocked by benzyloxycarbonyl group; a synthetic renin antagonist
EMD 57464: a substrate analogue peptidomimetic containing a hydroxyethylene dipeptide isosteric unit in positions p1 and p'1
EMD 60263: a thiadiazinone derivative; a ca+2 sensitizer devoid of any phosphorodiesterase inhibiting properties; emd 60264 is an enantiomer of emd 60263
EMD 638683: inhibits serum- and glucocorticoid-inducible kinase 1 (sgk1)
EMD478761: a nonpeptide diastereomer benzoxazinone; an alpha(v)beta(3)/alpha(v)beta(5) integrin antagonist
EMD640744: a mixture of survivin-derived, partially modified hla class i-restricted peptides in montanide isa 51 vg
EMF-1 protein, Gallus gallus: has been sequenced; may play a role in tissue remodeling and wound healing; an avian gene; member of c-x-c family of chemokines
EMF01: contains rehmannia glutinosa, cornus officinalis, salvia mittiorrhiza, pueraria, schisandra chinensis, poria cocos and platycodon grandiflorum
EMF1 protein, Arabidopsis: possesses p-loop and lxxll elements; involved shoot architecture and flowering; isolated from arabidopsis thaliana; genbank af319968
EMF10 protein, Eristocophis macmahoni: a heteromeric disintegrin isolated from eristocophis macmahoni venom; an extremely potent and selective inhibitor of alpha5beta1 fibronectin receptor; amino acid