NLK-NML/MeSH-CZ-2025-notes huggingface dataset:
1-(4-(3-(4-benzylpiperazin-1-yl)propoxy)-2-hydroxyphenyl)ethan-1-one: has both acetylcholinesterase and monoamine oxidase b inhibitory activity; also has chelating, neuroprotective, and antioxidant activities
1-(4-(3-(4-fluorophenyl)-1H-pyrrolo(3,2-b)pyridin-2-yl)pyridin-2-ylamino)propan-2-ol: a p38 map kinase inhibitor
1-(4-(3-(hydroxyimino)-3-(2-methylpyridin-4-yl)-1-o-tolylpropyl)phenyl)piperidine-4-carboxylic acid: an agonist of g protein-coupled bile acid receptor 1 (gpbar1)
1-(4-(3-acetyl-2,4,6-trimethylphenyl)-2,6-cyclohexanedionyl)-O-ethyl propionaldehyde oxime: ; porphyrogenic agent which causes hepatic protoporphyria in mice
1-(4-(3-fluoro-4-(3-methyl-1,1-dioxo-6-phenyl(1,2)thiazinan-2-ylmethyl)phenyl)piperazin-1-yl)ethanone: a rorc inverse agonist
1-(4-(3-fluoropropoxy)styryl)-3,5-dimethoxybenzene: for imaging beta-amyloid plaques
1-(4-(4-(1-cyclopropylsulfonylcyclopropyl)-6-(3-methylmorpholin-4-yl)pyrimidin-2-yl)phenyl)-3-(2-hydroxyethyl)thiourea: inhibits both mtorc1 and mtorc2
1-(4-(4-(1H-pyrrol-1-yl)phenyl)piperazin-1-yl)-4-(5-(3,5-difluorobenzyl)-1-(2-fluorobenzyl)-2-oxo-1,2-dihydropyridin-3-yl)-2-hydroxybut-2-ene-1,4-dione: has both antitubercular and anti-hiv activities
1-(4-(4-(3,3-dibutyl-7-(dimethylamino)-2,3,4,5-tetrahydro-4-hydroxy-1,1-dioxido-1-benzothiepin-5-yl)phenoxy)butyl)-4-aza-1-azoniabicyclo(2.2.2)octane: inhibits the ileal apical sodium-codependent bile acid transporter
1-(4-(4-(4,6-dimethyl(1,3,5)triazin-2-yl)2,6,-dimethylpiperazin-1-yl)pyrimidin-2-yl)ethanol: a sorbitol dehydrogenase inhibitor
1-(4-(4-(adamant-1-yl)phenoxymethyl)-2-(4-bromophenyl)-1,3-dioxolan-2-ylmethyl)imidazole: has both antifungal and acntibacterial activities
1-(4-(4-(aminosulfonyl)phenyl)-1H-1,2,3-triazole)-2,3,4-tri-O-acetyl-6-O-(((bis((2-((2,2-dimethylpropionyl)sulfanyl)ethoxy))phosphoryloxy)ethyl))glucopyranoside: a carbonic anhydrase proinhibitor
1-(4-(4-chinolin-2-yl-piperazin-1yl)-butyl)piperidin-2-one: a piperazine derivative; 5-ht agonist
1-(4-(4-methoxyphenyl)piperazin-1-yl)-3-(6-nitrobenzo(d)(1,3)dioxol-5-yl)propan-1-one: has analgesic activity
1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo(h)(1,6)naphthyridin-2(1H)-one: an mtor inhibitor
1-(4-(5'-chloro-3,5-dimethyl-2,4'-bipyridin-2'-yl)piperazin-1-yl)-3-(methylsulfonyl)propan-1-one: a potent and selective smoothened antagonist that penetrates the blood-brain barrier
1-(4-(5,6,7,8-tetrahydronaphthyloxy)phenyl)-1-hydroxymethylphosphonic acid: inhibits myo-inositol monophosphatase
1-(4-(5-bromopyrimidin-2-ylsulfanyl)phenyl)-3-(2-nitrobenzoyl)urea: has antineoplastic activity
1-(4-(5-methoxy-2-(2-pyridyl)thiazolyl))-2-(3-(2-methylbenzo(b)thiophenyl))hexafluorocyclopentene: a photochromic compound
1-(4-(6-(2-(isopropylsulfonyl)phenylamino)-9H-purin-2-ylamino)-3-ethoxyphenyl)piperidin-4-ol: an mps1 inhibitor that sensitizes glioblastoma cells to antimitotic drugs
1-(4-(6-bromobenzo(1,3)dioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta(c)quinolin-8-yl)ethanone: g-1 was able to induce both c-fos expression and proliferation in the eralpha-negative/gpr30-positive skbr3 breast cancer cells, the requirement for eralpha expression in gpr30/egfr signaling may depend on the specific cellular context of different tumor types
1-(4-(6-chloro-7-(2-fluorophenyl)quinazolin-4-yl)piperazin-1-yl)prop-2-en-1-one: a kras g2c protein inhibitor with antineoplastic activity
1-(4-(benzo(d)(1,3)dioxol-5-ylmethyl)piperazin-1-yl)-5-(1,2-dithiolan-3-yl)pentan-1-one: a synthetic alpha-lipoic acid derivative
1-(4-(benzothiazol-2-yloxy)benzyl)piperidine-4-carboxylic acid: an nsaid with leukotriene a4 hydrolase inhibitory activity
1-(4-(difluoromethoxy)-3-((tetrahydrofuran-3-yl)oxy)phenyl)-3-methylbutan-1-one: reverses learning and memory deficits in mice
1-(4-(furo(2,3-b)quinolin-4-ylamino)phenyl)ethanone: anti-tumor agent
1-(4-(furo(2,3-b)quinolin-4-ylamino)phenyl)ethanone O-2-aminoethyloxime: an antineoplastic agent
1-(4-(methylsulfonyl)phenyl)-3-(1H-pyrrolo(2,3-b)pyridin-5-yl)-1H-pyrazolo(3,4-d)pyrimidin-4-amine: inhibits ataxia telangiectasia and rad3 related protein (atr)
1-(4-(octahydropyrido(1,2-a)pyrazin-2-yl)phenyl)-2-phenyl-1,2,3,4-tetrahydroisoquinolin-6-ol: an estrogen receptor modulator
1-(4-2'-fluoroethoxy-3-methoxyphenethyl)-4-(3-(4-fluorophenyl)propyl)piperazine: a sigma receptor ligand
1-(4-Cl-benzyl)-3-Cl-4-(CF3-phenylamino)-1H-pyrrol-2.5-dione: has cytostatic activity
1-(4-amino-3,5-dimethylphenyl)-3,5-dihydro-7,8-ethylenedioxy-4H-2,3-benzodiazepin-4-one: an ampa antagonist
1-(4-aminobenzyl)-3-(4-(methylthio)-1-(2-(2-(methylthio)phenyl)pyrrolidin-1-yl)-1-oxobutan-2-yl)urea: a cyclophilin d inhibitor
1-(4-aminobutyl)-3,4-dihydro-beta-carboline: a nazlinin derivative
1-(4-aminophenyl)-7,8-methylenedioxy-1,2,3,5-tetrahydro-4H-2,3-benzodiazepin-4-one: has anticonvulsant activity
1-(4-aminosulfonylphenylazo)-2-naphthol-6,8-disulfonate: a carbonic anhydrase inhibitor
1-(4-benzhydrylpiperazin-1-yl)-3,3-diphenylpropan-1-one: an n-type calcium channel blocker
1-(4-benzoyl-1-(3-fluoro-4-hydroxyphenyl)-1H-pyrrol-2-yl)-2,2-difluoroethanone: inhibits both aldose reductase and aldehyde reductase
1-(4-benzoyl-piperazin-1-yl)-2-(4-fluoro-7-(1,2,3)triazol-1-yl-1H-pyrrolo(2,3-c)pyridin-3-yl)-ethane-1,2-dione: virus attachment inhibitor
1-(4-benzoylbenzyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid: an m1 muscarinic acetylcholine receptor ligand
1-(4-benzylpiperidin-1-yl)-2-(6-hydroxy-1H-indol-3-yl)ethane-1,2-dione: an nmda receptor ligand
1-(4-bromo-2-nitroimidazol-1-yl)-3-fluoropropan-2-ol: a pet radiotracer for imaging hypoxia in the brain
1-(4-bromobenzoyl)-3-(4-ferrocenylphenyl) urea: has anticonvulsant, anxiolytic, and sedative properties in mouse model
1-(4-bromobenzyl)-4-(3-(cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one: bromobenzyl derivative of rolipram; rn given refers to (r)-isomer
1-(4-bromophenyl)-2-((5-(4-nitrophenyl)furan-2-yl)methylene)hydrazine: an f508del-cystic fibrosis transmembrane conductance regulator corrector
1-(4-bromophenyl)-3-(napthalen-2-yl)prop-2-en-1-one: has both antimicrobial and antioxidant activities
1-(4-bromophenyl)-5-mercapto-1,2,3,4-tetrazole: partial ; shows thyrostatic activity
1-(4-bromophenyl)-5-phenyl-1H-1,2,3-triazole: has antimicrobial activity against plant pathogens
1-(4-bromophenylaminocarbonyl)-4,5-diphenyl-3-pyrazolidinone: a diphenylpyrazolidinone; cholecystokin antagonist; decreases midbrain dopamine unit activity; ly288513 and ly288512 are optical isomers of lly262691
1-(4-carbamoylpyridinium)-3-(4-hydroxyiminomethylpyridinium)-2-oxapropane: a acetylcholinesterase reactivator
1-(4-carbamoylpyridinium)-4-(3-fluoro-4-hydroxyiminomethylpyridinium)-but-2-ene: reactivates tabun-inhibitor acetylcholinesterase
1-(4-carbamoylpyridinium)-4-(4-hydroxyiminomethylpyridinium)but-2-ene: an acetylcholinesterase reactivator
1-(4-carboxyphenyl)-3,3-dimethyltriazene: rn given refers to parent cpd
1-(4-carboxypyridinium)-4-(4-hydroxyiminomethylpyridinium)-but-2-ene: reactivates tabun-inhibited acetylcholinesterase
1-(4-chloro-3-(4-ethoxybenzyl)phenyl)-1,6-dideoxyglucopyranose: inhibits sodium-dependent glucose cotransporter 2 (sglt2)
1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(2-((quinolin-4-ylmethyl)amino)pyridin-3-yl)urea: a kinase insert domain-containing receptor (kdr) kinase inhibitor
1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(3-(2-methyl-6-morpholinopyrimidin-4-ylamino)phenyl)urea: has antineoplastic activity
1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(6-(3-((2-(piperidin-1-yl)ethylamino)methyl)-1H-indazol-1-yl)pyidin-3-yl)urea: has both anti-angiogenic and antineoplastic activities
1-(4-chloro-3-trifluoromethyl-benzyl)-5-hydroxy-1-H-indole-2-carboxylic acid: a chemokine receptor antagonist intended for treating inflammatory conditions
1-(4-chlorobenzoyl)-1,2-dihydro-2-quinolinecarbonitrile: ; antagonizes hiv-1 reverse transcriptase; rn given for (+-)-isomer; rn for cpd without isomeric designation not available 8/93
1-(4-chlorobenzoyl)-3-(2-(1H-imidazol-1-yl)-2-oxoethyl)-5-methoxy-2-methyl-1H-indole: inactivates prostaglandin endoperoxide synthase
1-(4-chlorobenzoyl)-5-hydroxy-2-methyl-3-indoleacetic acid: has insulin sensitizing and glucose lowering activity
1-(4-chlorobenzylidine)-5-methoxy-2-methyl-3-indeneacetic acid: rn given refers to parent cpd
1-(4-chlorobutyl)-1,2-dihydro-N-(4-methylcyclohexyl)-2-oxo-1,8-naphthyridine-3-carboxamide: a selective cb2 cannabinoid receptor agonist with anit-proliferative and pro-apoptotic properties
1-(4-chlorophenyl)-2-(3,4-dihydroquinolin-1(2H)-yl)ethyl 4-nitrophenylcarbamate: an hiv-1 reverse transcriptase inhibitor
1-(4-chlorophenyl)-2-(3,4-dihydroquinolin-1(2H)-yl)ethyl o-tolylcarbamate: an hiv-1 reverse transcriptase inhibitor
1-(4-chlorophenyl)-3-(3-((2,4-dichlorophenyl)amino)-1,1-dioxidobenzo(d)isothiazol-5-yl)urea: has antineoplastic activity
1-(4-chlorophenyl)-3-(3-(4-chlorophenyl)-5,5-dimethyl-1-(3-(5-nitrofuran-2-yl)allyldienehydrazinocarbonylmethyl)-2-oxoimidazolidin-4-yl)-1-hydroxyurea: stabilizes dislocation substrates in the endoplasmic reticulum membrane and thereby affects degradation of misfolded type i membrane proteins
1-(4-chlorophenyl)-3-(4-(2-methoxyethyl) piperazin-1-yl)methyl-2-pyrrolidinone tartrate: sigma receptor ligand
1-(4-chlorophenyl)-3-(4-nitrophenyl)prop-2-en-1-one: inhibits monoamine oxidase a
1-(4-chlorophenyl)-4,4,4-trifluoro-3-hydroxy-2-buten-1-one: has antibacterial activity
1-(4-chlorophenyl)-4,4-dimethyl-5-diethylamino-1-penten-3-one: reacts irreversibly with protein thiols but reversibly with small molecular weight thiols; ; rn given refers to the hbr; its conjugation to glutathione is catalyzed selectively by alpha-class glutathione s-transferase
1-(4-chlorophenyl)-4-morpholin-1-yl-1,5-dihydroimidazol-2-one: a gaba(a) receptor modulator
1-(4-chlorophenyl)-4-piperidin-1-yl-1,5-dihydroimidazol-2-one: an anxiolytic agent that is an agonist at the benzodiazepine binding site of the gaba-a receptor
1-(4-chlorophenyl)-N,N-dimethyl-1-ethyl-(4-phenyl)but-3-en-1-ylamine: may have potential use in the treatment of urinary incontinence
1-(4-chlorophenyl)-benzo-2,5-quinone: enhances cyp1a1 expression
1-(4-chlorophenyl)piperazine: increases serotonin & decreases 5-hydroxyindoleacetic acid concentration in rat brain 6 hours after administration; rn given refers to parent cpd
1-(4-chlorophenylhydrazono)-1-(4-chlorophenylamino)-3,3-dimethyl-2-butanone: an s1p3 sphingosine receptor antagonist
1-(4-cyanobenzyl)-4-(((iodopropen-2-yl)oxy)methyl)piperidine: binds to sigma receptors
1-(4-cyanophenyl)-7-(4-(N-methylacetamido)phenyl))-1,7-dicarba-closo-dodecaborane: a progesterone receptor antagonist
1-(4-dimethylaminomethylphenyl)-8,9-dihydro-7H-2,7,9a-benzo(cd)azulen-6-one: a radiosensitizing agent that inhibits poly(adp-ribose) polymerase-1
1-(4-dimethylaminophenyl)-2-(5H-phenanthridine-6-ylidene)ethanone: a solvatochromic dye
1-(4-ethoxy-3-methoxyphenyl)-2-phenoxypropane-1,3-diol: a non-phenolic lignin dimer
1-(4-ethylphenyl)-3-(2-pyridinyl)-2-propen-1-one: inducer of ferroptosis; opens voltage dependent anion channels (vdac) to induce oxidative stress and cell death in cancer cells
1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane: gaba(a) receptor ligand for autoradiography
1-(4-fluoro-2-(2-nitrovinyl)phenyl)pyrrolidine: has anti-inflammatory activity
1-(4-fluoro-3-chlorophenyl)-3-(1H-1,2,4-triazol-3-yl)thiourea: has antibacterial activity
1-(4-fluorobenzyl)-4-((5,6-dimethoxy-1-oxoindan-2-fluoro-2-yl)methyl)piperidine: unsuccessful radioligand for acetylcholinesterase
1-(4-fluorobenzyl)-4-((5,6-dimethoxy-1-oxoindan-2-yl)methyl)piperidine: poor radioligand for visualizing acetylcholinesterase
1-(4-fluorophenethyl)-4-(2-methoxyphenethyl)piperidine: a vesicular monoamine transporter-2 inhibitor
1-(4-fluorophenyl)-1-(1-(4-fluorophenyl)-4a-methyl-4,4a,5,6,7,8-hexahydro-1H-benzo(f)indazol-5-yl)ethanol: a glucocorticoid receptor ligand with nsaid activity
1-(4-fluorophenyl)-2-(4-(phenylsulfonyl)-1-piperidinyl)ethanone: a 5-ht(2a) receptor antagonist
1-(4-fluorophenyl)-2-methyl-3-(thiomorpholin-4-yl)methyl-5-(4-methylphenyl)-1H-pyrrole: has antitubercular activity
1-(4-fluorophenyl)-2-oxo-N-(4-((2-(thiophen-3-yl)-3H-imidazo(4,5-b)pyridin-7-yl)oxy)phenyl)-1,2-dihydropyridine-3-carboxamide: a c-met kinase inhibitor
1-(4-fluorophenyl)-3-(3-(4-fluorophenyl)-4-hydroxybut-2-enyl)-4-(4-hydroxyphenyl)-2-azetidinone: a cholesterol absorption inhibitor
1-(4-fluorophenyl)-8-(2-(4-fluorophenyl)-2-hydroxycyclohexyl)-1,3,8-triazaspiro(4.5)decan-4-one: inhibits glycine transporter-1
1-(4-fluorophenylthiocarbamoyl)-4-methylpiperazine: reduces cytotoxic and genotoxic effects of paraquat in hordeum vulgare and cultured human lymphocytes
1-(4-hydroxy-2-(1-hydroxy-1-methyl-ethyl)-2,3-dihydro-benzofuran-5-yl)-3-(3-(3-methyl-2-butenyl)-4-hydroxy-phenyl)-2-propen-1-one: from hedysarum gmelinii
1-(4-hydroxy-3-((4-(4-(3-(pyridin-3-yl)acryloyl)phenyl)piperazin-1-yl)methyl)phenyl)-3-(pyridin-3-yl)prop-2-en-1-one: an antineoplastic agent
1-(4-hydroxy-3-methoxyphenyl)-2-(4-(3-hydroxypropyl)-2-methoxyphenoxy)propane-1,3-diol: isolated from the bark of pinus sylvestris
1-(4-hydroxy-3-methoxyphenyl)-7-(3,4-dihydroxyphenyl)-4E-en-3-heptanone: antineoplastic
1-(4-hydroxybenzyl)-4-methoxy-2,7-dihydroxy-phenanthrene-8-O-beta-D-glucoside: cytotoxic cpd from cremastra appendiculata
1-(4-hydroxybenzyl)-6,7-methylenedioxy-2-methylisoquinolinium trifluoroacetate: antimalarial alkaloid from the rainforest tree doryphora sassafras
1-(4-hydroxybenzyl)imidazole: active substrate for dopamine beta-hydroxylase
1-(4-hydroxybenzyl)imidazole-2-thiol: rn & ; rn not in chemline 3/87
1-(4-hydroxyiminomethylpyridinium)-3-pyridiniumpropane: a cholinesterase reactivator
1-(4-hydroxyiminomethylpyridinium)-4-(4-carbamoylpyridinium)butane: an acetylcholinesterase reactivator
1-(4-hydroxyiminomethylpyridinium)-4-(4-methylcarbonylpyridinium)-but-2-ene: reactivates tabun-inhibited acetylcholinesterase
1-(4-hydroxyphenyl)-1-phenyl-2-(4-pyridinyl)ethene: binds to estrogen receptor
1-(4-hydroxyphenyl)-2-bromoethanone: electrochemical active reagent
1-(4-hydroxyphenyl)-3-cyano-4-methyl-pyridone-2: cyanopyridone compound with antitumor activity
1-(4-hydroxyphenyl)-3-m-tolylpropenone: has antiulcer activity
1-(4-hydroxyphenylethyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline: induces expression of ho-1 by stimulating nrf2-are binding activity
1-(4-imidazopyridinyl-7-phenyl)-3-(4'-cyanobiphenyl)urea: inhibits cyp3a4
1-(4-iodophenoxymethyl)-benzo(f)coumarin: a fluorescent dye
1-(4-iodophenylsulfonyl)-N-(1-oxo-3-phenylpropan-2-yl)pyrrolidine-2-carboxamide: a mu-calpain inhibitor
1-(4-isopropyl-phenyl)-beta-carboline-3-carboxylic acid: an inhibitor of gpiib-iiia and p-selectin receptors
1-(4-isopropylcyclohexyl)-5'-methyl-2'-phenylhexahydrospiro(piperidine-4,1'-pyrrolo(3,4-c)pyrrole): a nociceptin/orphanin fq receptor agonist
1-(4-methoxy)phenyl-3-methyl-5-pyrazolone: ; used to label oligosaccharides of glycoproteins
1-(4-methoxy-2-methylphenyl)piperazine: has nootropic activity
1-(4-methoxy-3,5-dimethylbenzyl)-4-(3-(ethylamino)-2-pyridyl)piperazine hydrochloride: inhibits hiv-1 reverse transcriptase
1-(4-methoxy-3-(6-methoxy-3-acetylphenylperoxy)phenyl)ethanone: from the rhizome of cynanchum otophyllum schneid (asclepiadaceae)
1-(4-methoxybenzyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid: has been shown to exhibit unprecedented positive allosteric activity for ach binding as well as inherent agonist activity at the m1 muscarinic receptor
1-(4-methoxyphenyl)-2-((5-phenylthiophen-2-yl)methylene)hydrazine: an f508del-cystic fibrosis transmembrane conductance regulator corrector
1-(4-methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)ethene: inhibits tubulin polymerization; rn &
1-(4-methoxyphenyl)-3-acetamido-4-methoxyazetidin-2-one: an active site-directed inhibitor of a class a beta-lactamase from bacillus cereus
1-(4-methoxyphenyl)-5-(3,4,5-trimethoxyphenyl)-1H-(1,2,4)triazole-3-carboxylic acid hydrazide: an anti-inflammatory agent that inhibits cyclooxygenases 1 and 2
1-(4-methoxyphenyl)-5-(3,4,5-trimethoxyphenyl)-1H-(1,2,4)triazole-3-carboxylic acid methylamide: an anti-inflammatory agent that inhibits cyclooxygenases 1 and 2
1-(4-methoxyphenyl)pyridinium: rn given refers to parent cpd
1-(4-methoxyphenylethyl)-6-methylbenzo(c)-1,2-dihydropyrido(2,3-f)(1,2,5)thiadiazepine 5,5-dioxide: has antineoplastic activity; inhibits tubulin polymerization
1-(4-methoxypyridin-3-ylmethyl)-4-((N-(7-(3-(S)-1-carbamoyl-1,1-diphenylmethyl)pyrrolidin-1-yl)hept-1-yl)-N-(isopropyl)amino)piperidine: a bladder selective muscarinic receptor antagonist
1-(4-methyl-1-piperazinyl)pyrrolo(1,2-a)quinoxaline: a serotonin receptor (5ht2) agonist
1-(4-methylphenyl)-1H-1,2,3-triazole-4-carbaldehyde: an antitubercular agent
1-(4-methylphenyl)-2-pyrrolidin-1-ylhexan-1-one: a designer drug on the illicit drug market; it is mainly metabolized to 4'-hydroxymethyl-alpha-pyrrolidinohexanophenone followed by oxidation to the respective carboxylic acid
1-(4-methylphenyl)-3-(2,3-dihydroxyphenyl)-2-propenone: a beta-lactamase inhibitor
1-(4-methylphenyl)propane-2-amine: has serotonergic activity
1-(4-methylpiperazin-1-yl)-3-(5-nitrofuran-2-yl)prop-2-en-1-one: a p73 protein-stimulating compound that restores p53 signaling
1-(4-methylthiophenyl)-2-aminopropane: a putative empathogen
1-(4-nitro-2-(trifluoromethyl)phenyl)-4-(3-(trifluoromethyl)phenyl)piperazine: for treatment of benign prostatic hyperplasia
1-(4-nitrophenyl)-2-(4,5,6,7-tetrahydro-2-imino-3(2H)-benzothiazolyl)ethanone: a p53 inhibitor
1-(4-nitrophenyl)-2-(methionylsulfonamido)-1,3-propadiol: inhibits helicobacter pylori aminoacyl-trna amidotransferase
1-(4-nitrophenylsulfonyl)-N-(1-oxo-3-phenylpropan-2-yl)pyrrolidine-2-carboxamide: a mu-calpain inhibitor
1-(4-propoxy-3-(6,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-d)pyrimidin-5-yl)phenylsulfonyl)-4-methylpiperazine: sildenafil analog
1-(4-pyrimidinyl)-4-(1-(4-bromophenylsulfonyl)piperazin-4-ylcarbonyl)piperidine: inhibits 2,3-oxidoqualene cyclase-lanosterol synthase
1-(4-pyrrolidinoethoxyphenyl)-2-phenyl-7-methoxybenzosuberan: anti-implantation agent
1-(4-sulfamoylphenylethyl)-2,4,6-triphenylpyridinium: a carbonic anhydrase inhibitor
1-(4-sulfanatobutyl)-4-(beta-(2-(di-n-butylamino)-6-naphthyl)butadienyl)quinolinium betaine: a potentiometric dye
1-(4-thiazolyl)-3-cyano-1-propanone: metabolite of the carcinogen,4-(5-nitro-2-furyl)thiazole
1-(4-toluenesulfonyl)cytosine: has antineoplastic activity
1-(4-tosyl)-3,4,4-trimethylimidazolidine: structure (methyl groups missing hydrogen) given in first source; a functional analog for tetrahydrofolate-mediated one-carbon transfer
1-(4-trifluoromethoxyphenyl)-3-(4-(5-trifluoromethyl-2,5-dihydropyrazol-1-yl)phenyl)urea: has antineoplastic activity
1-(5'-bromosalicylidene)-2-(2''-pyridyl)hydrazine: ; type 2 double prime as two apostrophes, not quote marks
1-(5'-methylfur-3'-yl)propane-1,2,3-triol: isolated from streptomyces
1-(5(Or 6)-methyl-7(or 8)-(1-methylethyl)bicyclo(2.2.2)oct-5-en-2-yl)ethan-1-one: a member of the fragrance structural group alkyl cyclic ketones
1-(5,5,5-trichloro-2-methoxy-4-oxopenten-2-yl)-4-trichloromethylpyrimidin-2(1H)-one: has antineoplastic activity
1-(5,5-dimethyl-3-naphthalen-1-yl-1-(3-(5-nitrofuran-2-yl)allyldienehydrazinocarbonylmethyl)-2-oxoimidazolidin-4-yl)-3-naphthalen-1-yl-1-hydroxyurea: stabilizes dislocation substrates in the endoplasmic reticulum membrane and thereby affects degradation of misfolded type i membrane proteins
1-(5,8-dihydro-1,4-dihydroxy-5,8-dioxo-2-naphthyl)-4-methylpent-3-en-1-yl cinnamate: a naphthazarin
1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydronaphthalen-2-yl)-4-methylpent-3-enyl 2-(thiophen-3-yl)acetate: has antineoplastic activity
1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydronaphthalen-2-yl)-4-methylpent-3-enyl 3-(1H-indol-3-yl)propanoate: has antineoplastic activity
1-(5-((2,4-difluorophenyl)thio)-4-nitrothiophen-2-yl)ethanone: a usp7 inhibitor
1-(5-(1H-indol-5-yl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine: a potassium-competitive acid blocker
1-(5-(2-(2-N-ethylbenzothiazolinium)ethenyl)-2-aminophenoxy)-2-(2-amino-5-methylphenoxy)ethane-N,N,N',N'-tetraacetic acid: fluorescent calcium probe
1-(5-(2-(3,5-dimethoxyphenyl)vinyl)-2-methoxyphenyl)-3-(2-morpholin-4-ylethyl)urea: has antineoplastic activity
1-(5-(2-bromovinyl)-2-(hydroxymethyl)-1,3-(dioxolan-4-yl))uracil: has antiviral activity
1-(5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine: a proton pump inhibitor
1-(5-(2-formlfuryl)methyl)dihydrogen 2-hydroxypropane-1,2,3-tricarboxylate 2,3-diethyl ester: from fruits of morus alba l
1-(5-(2-thenyloxy)-1H-indol-3-yl)propan-2-amine: a 5-ht(2b) agonist
1-(5-(3,5-dichloro-2-(2,6-dinitro-4-(trifluoromethyl)phenoxy)phenyl)-3-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)ethanone: an antibacterial with dna gyrase inhibitory activity
1-(5-(3-((1-(4-fluorobenzyl)-1H-1,2,3-triazol-4-yl)methoxy)-4-methoxyphenyl)-3-(3,4,5-trimethoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)ethanone: has antineoplastic activity
1-(5-(3-(2,6-dimethylpyridin-3-yloxy)-5-(pyridin-2-ylthio)pyridin-2-ylamino)-1,2,4-thiadiazol-3-yl)ethane-1,2-diol: a glucokinase activator
1-(5-(4-bromo-2-chlorophenyl)furan-2-yl)-N-((piperidin-4-yl)methyl)methanamine: has antimalarial activity against both asexual stages and gametocytes of plasmodium falciparum
1-(5-(4-bromophenoxy)pentyl)-3-(4-pyridyl)-2-imidazolidinone: targets enterovirus 71 capsid protein vp1
1-(5-(4-chlorobenzoyl)-1-methyl-1H-pyrrol-3-yl)-2-(diethylamino)ethanone: an analgesic
1-(5-(4-methoxyphenyl)-1,3,4-thiadiazol-2-yl)-3-(pyridine-3-yl)urea: an acetylcholinesterase inhibitor
1-(5-(5'-chloro-3,5-dimethyl-(2,4'-bipyridin)-2'-yl)-4,5,6,7-tetrahydrothiazolo(5,4-c)pyridin-2-yl)piperidin-4-ol: a smoothened protein antagonist
1-(5-(5-chloro-2-(2,6-dinitro-4-(trifluoromethyl)phenoxy)phenyl)-3-(p-tolyl)-4,5-dihydro-1H-pyrazol-1-yl)ethanone: an antibacterial with dna gyrase inhibitory activity
1-(5-(5-chloro-2-hydroxyphenyl)-3-(p-tolyl)-4,5-dihydro-1H-pyrazol-1-yl)ethanone: a braf kinase inhibitor
1-(5-(7-(3-morpholinopropoxy)quinazolin-4-ylthio)-(1,3,4)thiadiazol-2-yl)-3-p-tolylurea: an flt3 inhibitor with antineoplastic activity
1-(5-(hydroxymethyl)bicyclo(3.1.0)hex-3-en-2-yl)-5-methyl-1,3-dihydropyrimidine-2,4-dione: a conformationally locked stavudine analog
1-(5-O-(5-amino-5-deoxyribopentofuranosyl)-5-(4-palmitoylaminohexahydro-2-pyridyl)ribopentofranosyl)uracil: an antibacterial agent with phospho-murnac-pentapeptide translocase (mray) inhibitory activity
1-(5-acetyl-2,4-dihydroxyphenyl)-3-methylbutan-1-one: from sargassum thunbergii
1-(5-acetyl-2-hydroxy-4-methoxyphenyl)-3-methylbutan-1-one: from sargassum thunbergii
1-(5-azido-6-chloropyridin-3-ylmethyl)-2-nitroiminoimidazolidine: a nicotinic acetylcholine receptor photoaffinity probe
1-(5-bromo-2-hydroxy-4-methoxyphenyl)ethanone: an anti-inflammatory agent isolated from the sea horse hippocampus kuda
1-(5-bromopentyl)-3-(1-naphthoyl)indole: an agonist of both cb1 and cb2 cannabinoid receptors
1-(5-carboxyindol-1-yl)propan-2-one: inhibits human cytosolic phospholipase a2alpha
1-(5-chloro-1-((2,4-dimethoxyphenyl)sulfonyl)-3-(2-methoxyphenyl)-2-oxo-2,3-dihydro-1H-indol-3-yl)-4-fluoro-N,N-dimethylprolinamide: an arginine vasopressin v(1b) receptor antagonist with both antidepressant and anxiolytic activities
1-(5-chloro-1-((2,4-dimethoxyphenyl)sulfonyl)-3-(2-methoxyphenyl)-2-oxo-2,3-dihydro-1H-indol-3-yl)-4-hydroxy-N,N-dimethyl-2-pyrrolidinecarboxamide: ssr-149415 is the (2s,4r)-isomer
1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea: an alpha7nachr agonist
1-(5-chloro-2-hydroxyphenyl)-3-(2-chloro-5-trifluoromethylphenyl)urea: an alpha7 nicotinic acetylcholine receptor modulator that may have cognitive enhancing activity
1-(5-chloro-2-methyl-phenyl)-3-(4-(5-trifluoromethyl-pyrazol-1-yl)-phenyl)thiourea: antineoplastic
1-(5-chloro-6-(3-methyl-4-(6-(trifluoromethyl)-4-(3,4,5-trifluorophenyl)-1H-benzo(d)imidazol-2-yl)piperazin-1-yl)pyridin-3-yl)ethane-1,2-diol: a trpv1 antagonist
1-(5-chloro-6-(trifluoromethoxy)-1H-benzoimidazol-2-yl)-1H-pyrazole-4-carboxylic acid: inhibits hypoxia-inducible factor prolyl hydroxylase
1-(5-chloroindol-3-yl)-3-hydroxy-3-(2H-tetrazol-5-yl)propenone: an hiv-1 integrase inhibitor
1-(5-chloropentyl)-3-(1-naphthoyl)indole: an agonist of both cb1 and cb2 cannabinoid receptors
1-(5-chloropyridin-3-yl)-(1,4)diazepane: an alpha4beta2 nicotinic receptor partial agonist
1-(5-chlorothien-2-yl)-2-(1H-imidazol-1-yl)ethanone 2,6-dichlorophenylhydrazone: rn from first source refers to hcl, (e)-isomer
1-(5-dimethylaminonaphthalene 1-sulfonamido)decane-10-trimethylammonium: fluorescent probe; rn & n1 are for l-(+)-tartrate
1-(5-ethoxypyridin-3-yl)-1,4-diazepane: an alpha4beta2 acetylcholine receptor partial agonist
1-(5-fluoropentyl)-3-(1-naphthoyl)indole: a cannabimimetic
1-(5-fluoropentyl)-3-(4-methyl-1-naphthoyl)indole: a cannabinoid receptor agonist
1-(5-hydroxy-2,2-dimethyl-2H-chromen-6-yl)-3-(2,3,4-trimethoxyphenyl)prop-2-en-1-one: a monoamine oxidase b inhibitor
1-(5-hydroxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)-6-methyl-1,3-dihydrofuro(3,4-c)pyridine-7-ol: inhibits advanced glycation, oxidative stress, and er stress; a neuroprotective agent
1-(5-methoxy-2-(2-nitrovinyl)phenyl)pyrrolidine: suppresses toll like receptor signaling pathways
1-(5-methoxybenzofuran-3-yl)-2-aminopropane: ; exhibits some binding to 5-ht2 and 5-ht1a serotonin receptors; benzofuran analog of 5-methoxy-alpha-methyltryptamine
1-(5-methyl-1H-benzimidazol-2-yl)-4-benzyl-3-methyl-1H-pyrazol-5-ol: inhibits both prostate cancer antigen-1 and alkbh3; has antineoplastic activity
1-(5-methyl-1H-pyrrol-2-yl)-2-((2S,3R)-3-((E)-prop-1-enyl)oxiran-2-yl)ethanone: isolated from the endophytic fungus s20 of cephalotaxus hainanensis
1-(5-nitro-2-furyl)-2-(phenylsulfonyl)-2-(furylcarbonyl)ethylene: inhibits (na/k)-atpase
1-(5-oxotetrahydrofuran-2-yl)ethyl 2-phenylacetate: from the marine nigrospora sphaerica
1-(5-pyrazolazo)-2-naphthol: for analysis of bismuth ions
1-(5-tertbutylindan-1-yl)-3-isoquinolin-5-ylurea: a-778317 is the (r)-isomer; a trpv1 receptor antagonist
1-(6,6-bis(4-fluorophenyl)hexyl)-4-(3,4,5-trimethoxybenzyl)piperazine: antagonist of above calcium channels
1-(6,9,12,15-octadecatetraenoyl)glycerol: isolated from sargassum sagamianum
1-(6-((2-(dimethylamino)ethyl)(methyl)amino)-1,3-dimethyl-1H-pyrazolo(3,4-b)pyridine-5-carbonyl)-3-(3-isopropoxyphenyl)urea: a c-c chemokine ligand 2 antagonist
1-(6-(2-chloro-4-methoxyphenoxy)hexyl)imidazole hydrochloride: antiviral cpd that has inhibitory activity against a number of picornavirus infections
1-(6-(3,4-dihydroisoquinolin-2(1H)-yl)hex-3-en-1-yl)-1,3-dihydro-2H-indol-2-one: a serotonin 5-ht7 receptor antagonist
1-(6-(3,5-dichloro-4-hydroxyphenyl)-4-((4-((dimethylamino)methyl)cyclohexyl)amino)-1,5-naphthyridin-3-yl)ethanone: a melk inhibitor
1-(6-(4-azido-2,3,5,6-tetrafluorobenzamido)hexyl)-3-cyclohexylcarbodiimide: reacts with dccd (dicyclohexylcarbodiimide) sites in proteins
1-(6-(4-bromophenyl)furo(2,3-d)pyrimidin-2-on-3-yl)-2-(2',3'-di-O-benzyl-2'-buten-4'-olidylidene)ethane: has antiviral activity
1-(6-(4-fluorophenyl)pyridin-3-yl)-3-(4-piperidin-1-ylbutyl)urea: an alpha7 nicotinic acetylcholine receptor agonist
1-(6-aziridinylhexyl)-2-(4-hydroxyphenyl)indol-5-ol: fluorescent label for estrogen receptors
1-(6-butyl-3,4-dihydro-2H-pyran-2-yl)pentanone: part of defensive secretions of five neotropical species of harvestmen (opiliones: gonyleptidae) from the brazilian atlantic forest
1-(6-butylfuro(2,3-d)pyrimidin-2-on-3-yl)-2-(2',3'-di-O-benzyl-2'-buten-4'-olidylidene)ethane: has antiviral activity
1-(6-chloro-3-pyridylmethyl)-4,4-dimethyl-2-nitromethyleneimidazolidine: insecticide
1-(6-chloro-3-pyridylmethyl)-5,5-dimethyl-2-nitromethyleneimidazolidine: insecticide
1-(6-chloro-3-pyridylmethyl)-7-methyl-8-nitro-1,2,3,5,6,7-hexahydroimidazo(1,2-a)pyridin-5-ol: an insecticide
1-(6-chloro-5-(4-(4-fluorobenzyl)-2,5-dimethylpiperazine-1-carbonyl)-3aH-indol-3-yl)-2-morpholinoethane-1,2-dione: a p38alpha mitogen-activated protein kinase inhibitor
1-(6-deoxy-6-iodogalactopyranosyl)-2-nitroimidazole: an hypoxia marker
1-(6-ethoxy-5-(3-ethyl-6,7-dihydro-2-(2-methoxyethyl)-7-oxo-2H-pyrazolo(4,3-d)pyrimidin-5-yl)-3-pyridyl sulphonyl)-4-ethylpiperazine: a phosphodiesterase inhibitor
1-(6-fluoro-2-methyl-3,4-dihydroquinolin-1(2H)-yl)-2-(isoquinolin-5-yloxy)ethanone: a takeda g-protein-coupled receptor-5 agonist
1-(6-fluoro-3-(trifluoromethyl)phenyl)-1-methyl-3-(naphthalen-1-yl)guanidine: a pet radioligand for nmda receptors
1-(6-fluoro-5,7-dimethyl-1,3-benzothiazol-2-yl)-N-(2-(hydroxymethyl)cyclohexyl)piperidine-4-carboxamide: has both anti-pyretic and anti-inflammatory activities; inhibits prostaglandin e2 synthesis
1-(6-hydroxy-2-isopropenyl-1-benzofuran-5-yl)-1-ethanone: from petasites hybridus
1-(6-hydroxyhexyl)-3-(5-phenylisoxazole-3-yl)urea: a hypoxia-amplifying compound
1-(6-hydroxymethylinositol)-2-O-methyl-3-O-octadecyl-sn-glycerocarbonate: an akt inhibitor
1-(6-methoxy-4'-(trifluoromethyl)-3-biphenylyl)-N-(1-phenylethyl)ethanamine: a calcimimetic that reduces parathyroid hormone levels
1-(7-((1-(3,5-diethoxyphenyl)-3-(((3,5-difluorophenyl)(ethyl)amino)carbonyl)-4-oxo-1,4-dihydroquinolin-7-yl)oxy)heptyl)-1-methylpiperidinium bromide: is a potent, specific ileum apical sodium-dependent bile acid transporter (asbt) inhibitor
1-(7-(2-amino-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl)-3,4-dihydroisoquinolin-2(1H)-yl)-2-cyclopentylethanone: a histamine h4 receptor antagonist with antipruritic and anti-inflammatory activities
1-(7-(2-chlorophenyl)-8-(4-chlorophenyl)-2-methylpyrazolo(1,5-a)(1,3,5)triazin-4-yl)-3-(methylamino)azetidine-3-carboxamide: an anti-obesity agent
1-(7-(2-chlorophenyl)-8-(4-chlorophenyl)-2-methylpyrazolo(1,5-a)-(1,3,5)triazin-4-yl)-3-ethylaminoazetidine-3-carboxylic acid amide: an antiparkinson agent that antagonizes cb1 receptors
1-(7-bromo-1,4-dihydrothieno(3',2'-5,6)thiopyrano(4,3-c)pyrazole-3-carbonyl)-4-(2-fluorophenyl)piperazine: a 5-lipoxygenase inhibitor; structurein first source
1-(7-carboxyhexyl)imidazole: selectively inhibits thromboxane a(2) biosyn from pg endoperoxides
1-(7-chloro-2,2-bis(fluoromethyl)chroman-4-yl)-3-(3-methylisoquinolin-5-yl)urea: a trpv1 antagonist with analgesic activity
1-(7-fluoro-2,3-dihydro-1H-inden-1-yl)-4-(4-(4-(methanesulfonyl)piperazin-1-yl)phenyl)-N,N-dimethylpyrrolidin-3-amine: an inhibitor of the prc2 complex
1-(7-hydroxy-2,6-dimethyl-1-naphthyl)-4-methyl-3-pentanone: from callus of securinega suffruticosa
1-(7-methoxy-1H-indol-4-yloxy)-3-(2-(2-methoxyphenoxy)ethylamino)propan-2-ol: a cardiovascular agent
1-(7-methoxy-quinolinyl-4'-yl)-3,4-dihydro-beta-carboline: ; from trigonostemon lii
1-(7R-hydroxy-8-propenyl)-3-(3'-methoxy-1'-(8'-propenyl)phenoxy)-4-hydroxy-5-methoxybenzene: an immunomodulator and antileishmanial from nectandra leucantha
1-(8-(2,4-dichlorophenyl)-2-methylquinolin-4-yl)-1,2,3,6-tetrahydropyridine-4-carboxamide benzenesulfonate: corticotropin-releasing factor subtype 1 (crf(1)) receptor antagonist
1-(8-(2-(4-isobutylphenyl)propionyl)octyl)-3-N,N-dimethylcarbamoyl pyridinium bromide: anti-inflammatory and cholinesterase inhibitor bifunctional compound
1-(8-(hydroxymethyl)-1-(2-(2-methylpyrrolidin-1-yl)ethyl)-4,4a,7,8,9,9a-hexahydroindolo(1,14-fg)quinolin-6(1H)-yl)ethanone: an histamine h3 receptor inverse agonist
1-(8-bromobenzo(1,2-b;4,5-b')difuran-4-yl)-2-aminopropane: fatal poisoning reported with this potent hallucinogenic drug
1-(8-fluorooctyl)-2-nitroimidazole: lipophilic compound used for imaging brain hypoxia
1-(8-propenyl)-3-(3'-methoxy-1'-(8-propenyl)phenoxy)-4,5-dimethoxybenzene: an immunomodulator and antileishmanial from nectandra leucantha
1-(9-adenyl)cyclopentan-3-ol: a carbocyclic nucleoside
1-(9-anthryl)-2-propyl chloroformate: new precolumn reagents
1-(9-deazaadenin-9-yl)-1,4-dideoxy-1,4-imino-5-methylthioribitol: inhibits both methylthioadenosine phosphorylase and methylthioadenosine-s-adenosylhomocysteine nucleosidase
1-(9-deazaadenin-9-yl)methyl-3-hydroxy-4-methylthiomethylpyrrolidine: inhibits both methylthioadenosine phosphorylase and methylthioadenosine-s-adenosylhomocysteine nucleosidase
1-(9-fluorenyl)methyl chloroformate: used for tagging silica-based derivatization reagents in hplc
1-(9-iodophenanthrene-3-carbonyl)piperazine-2,3-dicarboxylic acid: has antinociceptive activity
1-(9-methyl-9-azabicyclo(3.3.1)non-3-yl)-1,3-dihydro-2H-indol-2-one: a ligand for alpha3beta4 nicotinic receptors
1-(9H-carbazol-9-yl)propan-2-yl-methanesulfonate: a fatty acid labeling reagent
1-(N(2)-(3,4-dibromo-N-((4-(3,4-dihydro-2(1H)-oxoquinazolin-3-yl)-1-piperidinyl)carbonyl)tyrosyl)lysyl)-4-(4-pyridinyl)piperazine: in clinical trials for treating acute migraine
1-(N(3)-deoxycytidyl)-2-(N(1)-deoxyguanosinyl)ethane: cross-linked dinucleoside isolated from dna treated with bcnu
1-(N)-fluoresceinylestrone thiosemicarbazone: fluoresein-labeled estrogen; interacts with estrogen target cells like the native hormone; visualizes the uptake, transport & distribution of estrogen in intact target cells
1-(N,O-bis(isoquinolinesulfonyl)-N-methyltyrosyl)-4-(4-fluorophenyl)piperazine: a p2x7 receptor antagonist
1-(N-(2-(Amidinoaminooxy)ethyl)amino)carbonylmethyl-6-methyl-3-(2,2-difluoro-2-phenylethylamino)pyrazinone: a thrombin inhibitor
1-(N-(2-hydroxy-5-azidobenzoyl)-2-aminoethyl)-4-(N-hydroxysuccinimidyl)succinate: labeled with (125)i; ; rn given refers to the (125i)-labeled cpd
1-(N-(2-hydroxyethyl)acetamido)-2-hydroxylaminoimidazole: produces strand breaks in dna
1-(N-(2-methoxybenzyl)acetylamino)-3-(1H-indol-3-yl)-2-(N-(2-(4-(piperidin-1-yl)piperidin-1-yl)acetyl)amino)propane: a selective nonpeptide substance p (neurokinin-1) receptor antagonist
1-(N-(3-(4-methyl-4-phenylpiperidin-1-yl)propyl)carboxamido)-6-(3,4-difluorophenyl)-5-methoxycarbonyl-4-methoxymethyl-2-oxo-1,2,3,6-tetrahydropyrimidine: an alpha(1a) adrenoceptor-selective antagonist
1-(N-(3-aminopropyl)-N-(3-ammoniopropyl)amino)diazen-1-ium-1,2-diolate-dextran: used to deliver nitric oxide transdermally
1-(N-(4-methoxyphenyl)benzimidoyl)-5-methyl-3-pyrazolecarboxylate: benzimidoylpyrazole moiety combines in one molecule some of the biological activities of sulfonylureas & biguanides
1-(N-6-amino-n-hexyl)carbamoylimidazole: irreversible inhibitor of urokinase, kidney-cell plasminogen activator, plasmin & beta-trypsin
1-(N-acetyl-6-aminohexyl)-3-hydroxy-2-methylpyridin-4-one: an iron chelating agent
1-(N-acetyl-ALYDKGYTSKEQKDCVGI)-2-arachidonoyl-3-stearoyl glyceride: an immunologically active lipopeptide from goat serum
1-(N-acetylmuramyl-alanyl-isoglutaminyl)-2,3-dipalmitoyl-sn-glycerol: activates alveolar macrophage tumoricidal activity & eradicates experimental metastases; rn given refers to (d-alpha)-isomer
1-(N-carbobenzoxy-gamma-glutamyl)indoline-2-carboxylic acid: rn & ; rn not in chemline 12/85
1-(N-carbobenzoxy-gamma-glutamyl)perhydroindoline-2-carboxylic acid: rn & ; rn not in chemline 12/85
1-(N-di-(4'-chlorophenyl)acetamido)-2-butanol: ; rn given is for racemic form
1-(N-diphenylacetamido)-2-butanol: ; rn given is for racemic form
1-(N-ethyl-N-nitrosamino)ethyl phosphate: rn given refers to parent cpd
1-(N-methyl-N-nitrosoamino)ethyl phosphate: rn given refers to parent cpd
1-(S)-hydroxy-2-(S,S)-valylamidocyclobutane-1-acetic acid: amino acid antimetabolite isolated from fermentation broth of streptomyces x-1092
1-(acetyloxy)-3,5,6,6a,7,8,9,10-octahydro-10-hydroxy-7,8-dimethyl-7-(3-methylpenta-2,4-dien-1-yl)naphtho(1,8a-c)furan-3,5-diyl dibutanoate: isolated from casearia sylvestris
1-(alpha,apha-dimethylbenzyl)-3-(4-methylphenyl)urea: herbicide & pesticide
1-(aminomethyl)cyclohexaneacetic acid 3-(nitrooxymethyl)phenyl ester: a nitric oxide-releasing compound
1-(aminooxy)-4-((3-nitro-2-pyridyl)dithio)butane: ; rn given is for hcl
1-(azocan-1-yl)dec-3-en-1one: has antineoplastic activity
1-(benzo(d)(1,2,3)thiadiazol-6-yl)-3-(2-cyclohexenylethyl)urea: a prmt3 inhibitor
1-(benzofuran-2-yl)-2-propylaminopentane: enhances impulse propagation mediated release of serotonin and catecholamines in the brain
1-(benzofurazan-5-ylcarbonyl)piperidine: an allosteric modulator of ampa receptors
1-(benzoyloxy)-2-cyclodecene-4,9-diyne-6,7,8-triol: a 10-membered enediyne triol
1-(beta-carboxyethyl)-3,3-dimethyl-6'-nitrospiro(indoline- 2,2'-2H-benzopyran): photochromic spiropyran cpd
1-(biphenyl-4-ylmethyl)-1,2,3,4-tetrahydroisoquinoline-6,7-diol: has antiglioma activity
1-(bis(4-fluorophenyl)methyl)piperazine: detriazinyl metabolite of flunarizine
1-(carboxyethylthio)tetradecane: ; alkylthio propionic acid, non-beta-oxidizable
1-(carboxymethylthio)tetradecane: ; alkylthio acetic acid, non-beta-oxidizable
1-(chrysen-6-yl)-3-(4-nitrophenyl)thiourea: antineoplastic
1-(coumaran-5-ylmethyl)-4-(2-thiazolyl)piperazine: central direct dopaminergic stimulant; rn given refers to parent cpd
1-(cyclohexylmethyl)-1H-indole-3-carboxylic acid 8-quinolinyl ester: a cb1 receptor ligand
1-(di-(2-pyridyl)methylene)-5-salicylidenethiocarbonohydrazide: ; rn given from toxlit 2/91
1-(diethylaminopropyl)-4-phenylpiperazine: potential brain imaging agent labeled with 125i
1-(diiodomethyl)sulfonyl-4-methyl benzene: rn given in first source
1-(dipropylamino-3-piperidinepropan-1-yl)-3-pentyloxyphenylcarbamate: a local anesthetic
1-(ethoxycarbonyl)-3-methoxy-3-phenyl-2-piperidinone: rn & ; rn not in chemline 3/84
1-(gamma-chloropropyl)-2-chloromethylpiperidine: nitrogen mustard type antitumor agent; rn given refers to parent cpd
1-(gamma-dimethylaminopropoxy)benzotriazole: rn given refers to citrate
1-(glycerophosphoryl)-myo-inositol 4,5-diphosphate P(4(5))-1-(2-nitrophenyl)ethyl ester: liberates gpip2 upon photolysis
1-(hexanoyl)phloroglucinol-alpha-D-arabinopyranoside: antiradical and cytotoxic; from decaspermum gracilentum
1-(hexanoyl)phloroglucinol-beta-D-glucopyranoside: antiradical and cytotoxic; from decaspermum gracilentum
1-(hexylthio) -2-(hexanoylamino)-1,2-dideoxy-sn-glycero-3-phosphoethanolamine: an inhibitor of cobra venom phospholipase a2
1-(hexylthio)-2-(hexanoylamino)-1,2-dideoxy-sn-glycero-3-phosphocholine: ; an inhibitor of cobra venom phospholipase a2
1-(hydroxyacetyl)pyrene: a fluorescent phototrigger for cell imaging
1-(hydroxymethyl)-3-(2-hydroxypropan-2-yl)-2-(5-methoxy-9H-beta-carbolin-1-yl)-cyclopentanol: inhibits topoisomerases i and iialpha; isolated from galianthe thalictroides
1-(hydroxymethyl)-3-(3-octylphenyl)cyclobutane: an s1p1/3 receptor antagonist prodrug
1-(hydroxymethyl)-6,7,8-trihydroxyindolizidine: a putative immunomodulating agent
1-(hydroxymethyl-4-vinyltetrahydrofuran-2-yl)uracil: has anti-hiv activity
1-(indol-4-yloxy)-3-(1-(4-azido-3-iodophenyl)-2-isobutylamine)-2-propanol: rn given refers to (+-)-isomer
1-(isopropylamino)-3-(5-((isopropylamino)methyl)-2-methoxyphenoxy)propan-2-ol: putative beta-adrenoceptor antagonist with antihypertensive activity
1-(m-aminophenyl)-2-cyclopropylaminoethanol.2HCl: rn given for di-hcl
1-(methanesulfonamido-1-naphthyloxy)-2-(N-(4-methane sulfonamidophenethyl)-N-acetamido)ethane: potential anti-arrhythmia agent
1-(methylimino-N-oxy)-6-(2-morpholinoethoxy)-3-phenyl-1H-indene-2-carboxylic acid ethyl ester: has weak adipogenic effects
1-(naphthalen-2-yl)-3-azabicyclo(3.1.0)hexane: a dual norepinephrine-dopamine transporter inhibitor
1-(nitrooxymethyl)-2-(nitrooxy)ethyl 7-(3,5-dihydroxy-2-(3-hydroxy-5-phenylpentyl)cyclopentyl)-5-heptenoate: an antihypertensive agent
1-(nitrosooxy)propan-2-ol and 2-(nitrosooxy)propan-1-ol drug combination: a nitric oxide donor
1-(o-nitrophenyl)-3-(-thiazolyl)triazene: used for determination of palladium by rayleigh light-scattering
1-(omega-diethylaminopropylamide)-2-methoxy-4-hydroxy-9,10-anthracenedione: weaker complexation ability to dna than adriamycin
1-(omega-diethylaminopropylamido)-4-hydroxy-9,10-anthracenedione: weaker complexation ability to dna than adriamycin
1-(p-beta-diethylaminoethoxyphenyl)-1,2-di(p-methoxyphenyl)but-1-ene: rn given refers to parent cpd with unspecified isomeric designation; structure 2-(p-(1,2-bis(p-methoxyphenyl)-1-butenyl)phenoxy)-triethylamine
1-(p-hydroxybenzyl)-4,7-dimethoxyphenanthrene-2,6-diol: from bletilla striata
1-(p-hydroxybenzyl)-4,7-dimethoxyphenanthrene-2,8-diol: from bletilla striata
1-(p-hydroxybenzyl)-4,7-dimethoxyphenanthrene-2-ol: from bletilla striata
1-(phenyl)-N'-(4-methoxybenzylidene)-9H-pyrido(3,4-b)indole-3-carbohydrazide: has antiviral activity
1-(phenylazophenylazo)-2-naphthol: a component of d&c red no. 17
1-(phenylcyclopropyl)methylamine: rn & ; rn not in chemline 1/86
1-(phenylthio)-2-aminopropane: racemic & s-isomer have hypertensive actions; r-isomer is inactive; ; rn given refers to cpd without isomeric designation
1-(piperidin-1-yl)-2-((3-(thiophen-2-yl)-(1,2,4)triazolo(4,3-b)pyridazin-6-yl)thio)butan-1-one: an lrrk2 kinase inhibitor
1-(pyren-1-yl)-4-(hydroxymethyl)pyrrolidin-3-ol: an iminosugar nucleoside
1-(pyridin-4-yl)ethyl acetate: intermediates in the synthesis of drugs such as akuamidine and heteroyohimidine, and anticonvulsants
1-(pyroglutamic acid)-beta-lipotropin: fraction isolated from ovine lipotropin; contains pyroglutamic acid instead of glutamic acid in position 1
1-(pyrrolidin-1-ylmethyl)-2-((6-chloro-3-oxoindan)formyl)-7-hydroxy-1,2,3,4-tetrahydroisoquinoline: a kappa opioid receptor agonist
1-(quinoxalin-6-ylcarbonyl)piperidine: modulates ampa receptor desensitization ; an analog of 1-(1,3-benzodioxol-5-ylcarbonyl)piperidine
1-(saligenin cyclic phospho)-9-biotinyldiaminononane: neuropathy target esterase antagonist; general structure of n-biotinylated saligenin phosphoramidates given in first source
1-(tert-butoxycarbonyl)-4-trifluoromethylsulfonyloxy-3-(oxazol-5-yl)indole: used in biaryl coupling reactions
1-(tert-butylamino)-3-(5-tert-butylaminomethyl-2-methoxyphenoxy)propan-2-ol: a beta-adrenergic receptor antagonist
1-(tetrahydro-4-hydroxy-5-(hydroxymethyl)furan-2-yl)pyrimidine-2,4(1H,3H)-dione: isolated from the indonesian sponge kaliapsis
1-2-isopropoxy-2-oxidodihydro-4H,6H-spiro(furo(3,2-d)(1,3,2)dioxaphosphinine-7,2'-oxetan)-6-yl)pyrimidine-2,4(1H,3H)-dione: a cyclic phosphate ester derivative and 2'-deoxy-2'-spirooxetane uridine nucleotide prodrug which inhibits hcv ns5b rna-dependent rna polymerase (rdrp).
1-3-methylbutyryl-N4-6-aminohexanoyl-piperazine: a small molecule proteinase activated receptor 2/par2 antagonist
1-4-dimethylaminophenyl-5-allyl-5-(beta-hydroxypropyl)barbituric acid: beta-hydroxypropyl moiety gives these barbiturates different pharmacological actions
1-4-hydroxymandelate oxidase (decarboxylating): 4-hydroxymandelic acid yields 4-hydroxybenzaldehyde
1-6-O-(2-(N-hydroxyaminocarbonyl)amino-2-deoxyglucopyranosyl)inositol 1-(n-octadecyl phosphate): a metalloenzyme inhibitor
1-Bpa-parathyroid hormone-related protein, recombinant: analog of parathyroid hormone (pth)-related protein (pthrp), singularly substituted with a photoreactive l-p-benzoylphenylalanine (bpa) at the first n-terminal position
1-C-octyl-2-oxa-3-oxocastanospermine: an alpha-glucosidase inhibitor
1-Cy5.5-1-deoxyfructose: a fluorescent probe for breast cancer imaging
1-Cys thiol transferase protein, S cerevisiae: display similarities with human omega class glutathione s-transferases
1-N,4-N-bis(4-(1H-benzimidazol-2-yl)phenyl)benzene-1,4-dicarboxamide: antiviral
1-N-(1,3-dihydroxy-2-propoxymethyl)-6-(tert-butyl)-5,6,7,8-tetrahydro-2,4-quinazolinedione: an acyclonucleoside
1-N-(2,2,6,6-tetramethyl-1-oxyl-4-piperidinyl) 5-N- (1-aspartate)-2,4-dinitrobenzene: spin label for bilirubin
1-N-(2-hydroxyethyl)acetamido-2-hydroxylaminoimidazole-glutathione conjugate: conjugate of sr 2508 hydroxylamine and glutathione
1-N-(4-aminobenzyl)-3,6,10,13,16,19-hexaazabicyclo(6.6.6)eicosane-1,8-diamine: a chelating agent
1-N-5-iodovaleramido-3,7,8-trichlorodibenzo-4-dioxin: ligand labeled with (125)i
1-N-butyryl-4-cinnamylpiperazine: rn given refers to parent cpd
1-N-methyl-4-mercaptohistidine disulfide: ; potential endogenous regulator in the redox control of chloroplast coupling factor 1 in dunaliella; isolated from cell-free extracts of the halotolerant green alga dunaliella salina
1-N-methyl-5-thiotetrazole: side chain of several new antibiotics associated with development of hypoprothrombinemia
1-N-methylamino-5-isocyanonaphthalene: nonselective fluorescent dye for staining of heterochromatin and rough endoplasmic reticulum
1-O-((N-glycolylneuraminosyl)-(2-4)-(N-acetylneuraminosyl)-(2-6)glucopyranosyl)ceramide: from the sea cucumber holothuria leucospilota
1-O-((N-glycolylneuraminosyl)-(2-6)-glucopyranosyl)ceramide: from the sea cucumber holothuria leucospilota
1-O-((fucopyranosyl-(1-11)-(N-glycolylneuraminosyl)neuraminosyl)-(2-4)-(N-aetylneuraminosyl)-(2-6)-glucopyranosyl)ceramide: from the sea cucumber holothuria leucospilota
1-O-(1,2-propanediol)-6-O-galloyl-beta-D-glucopyranoside: from fresh leaves of psidium guajava l.
1-O-(11',12'-methylene-octadecanoyl)glycero-3-phosphocholine: from the marine sponge, spirastrella abata
1-O-(12-(2-naphthyl)dodec-11-enyl)-2-O-decanoyl-sn-glycerol-3-phosphocholine: used in assay of phospholipase a2
1-O-(12-(N-(4-azido-2,3,5,6-tetrafluorobenzoyl))aminododecanoyl)-2-O-oleoyl-sn-glycero-3-phosphate: a photoaffinity label for pde4d3
1-O-(2',3',4',5'-tetrahydroxycyclopentyl)-3-O-(10''-methylhexadecyl)glycerol: isolated from the marine sponge petrosia
1-O-(2,4-dihydroxy)phenylacetyl glycerol: isolated from the seeds of nigella damascena
1-O-(2,4-dimethyl-3-(2-methyl-2-(3,4-dimethoxyphenylethylamino)ethoxy)phenyl)glucuronic acid: a phenoprolamine metabolite
1-O-(2-((2',6'-dichlorophenyl)amino)phenylacetyl)glucopyranuronic acid: a diclofenac metabolite
1-O-(2-(3-hydroxymethyl-2-methylphenyl)aminobenzoyl)glucopyranuronic acid: a mefenamic acid metabolite from urine
1-O-(2-N-stearoylsphinganine-1-phosphoryl)-2-O-(mannopyranosyl)inositol: a mannosylinositol-containing sphingophospholipid
1-O-(2-aminobenzoyl)-alpha-l-rhamnopyranoside: renoprotective metabolite from streptomyces sp. rb1 that resides in cuticle of south african termite macrotermes natalensis
1-O-(2-oxoindol-3-ylacetyl)-beta-D-glucopyranose: oxidative metabolite of indole-3-acetic acid from arabidopsis thaliana
1-O-(24-deoxycholyl)-2-deoxyglucopyranuronic acid: an affinity labeling reagent
1-O-(3-O-glucopyranosylbutyryl)pancratistatin: inhibits cell cycle progression through specific phase
1-O-(3-hydroxybutyryl)pancratistatin: inhibits cell cycle progression through specific phase
1-O-(3-hydroxytetrahydrofuran-4-yl)glucopyranoside 3,4,3'-trisphosphate: affects ins(1,4,5)p3 receptor
1-O-(4''-O-caffeoyl)-beta-glucopyranosyl-1,4-dihydroxy-2-(3',3'-dimethylallyl)benzene: from the aerial parts of phagnalon rupestre (asteraceae)
1-O-(4-(2-fluoroethylcarbamoyloxymethyl)-2-nitrophenyl)-O-glucopyronuronate: a beta-glucuronidase pet imaging agent
1-O-(5'-carboxypentyl)glycero-3-phosphothreonine: inhibits steroid receptor complex activation
1-O-(5,8,11,14,17-eicosapentaenoyl)-2-O-(9,12,15-octadecatrienoyl)-3-O-galactopyranosyl-sn-glycerol: isolated from sargassum thunbergii
1-O-(6'-sulfo-alpha-D-glucopyranosyl)-2,3-di-O-phytanyl-sn-glycerol: a sulfated glycoglycerolipid from archaebacterium
1-O-(6-carboxylhexyl)glycero-3-phosphoserine: used for evaluating glucocorticoid-receptor complex modulator activity
1-O-(7'-N,N-dimethylamino-3'-pentadecanoyl-1'-naphthyl)-2-O-methyl-sn-glycerophosphocholine: a fluorescent probe with antineoplastic activity
1-O-(7S,8R)-guaiacylglycerol-(6-O-E-caffeoyl)-beta-D-glucopyranoside: from lagerstroemia speciosa
1-O-(9',10'-methanohexadecanoyl)-sn-glycero-2,3-cyclic phosphate: cyclic phosphate isolated from physarum polycephalum
1-O-(9'-(1''-pyrenyl))nonylglycerol: a fluorescent ether lipid
1-O-(9,12,15-octadecatrienoyl)-2-(6,9,12,15-octadecatetraenoyl)-3-O-galactopyranosyl-sn-glycerol: isolated from sargassum thunbergii
1-O-(9-O-methyl-(N-acetyl-alpha-D-neuraminosyl)-(2-6)-beta-D-glucopyranosyl)ceramide: a monomethylated ganglioside possessing neuritogenic activity from the ovary of the sea urchin diadema setosum
1-O-(9Z,12Z-octadecadienoyl)-3-O-nonadecanoyl glycerol: from hyoscyamus niger seeds (solanaceae)
1-O-(E)-caffeoyl-beta-gentiobiose: nsaid from spathodea campanulata
1-O-(N-dabsyl-11-amino-1-undecyl)-2-O-decanoylphosphatidylcholine: fluorophore-labeled lipid substrate
1-O-(N-dansyl-11-amino-1-undecyl)-2-O-decanoylphosphatidylcholine: fluorophore-labeled lipid substrate
1-O-(beta-D-galactopyranosyl)-(2S,3S,4R,8Z)-2-((2'R)-2'-hydroxydocosanoilamino)-8(Z)-octadecene-1,3,4-triol: antineoplastic agent, phytogenic from euphorbia peplis l
1-O-(beta-D-glucopyranosyl)-(2S,3R,4E)-2-(heptadecanoylamino)-4-octadecene-l,3-diol: from marine bryozoan bugula neritina inhabiting south china sea