NLK-NML/MeSH-CZ-2025-notes huggingface dataset:
coleoptericin Bm protein, Allomyrina dichotoma: isolated from larvae of the beetle, allomyrina dichotoma; genbank ab021309
coleoptericin protein, insect: an antibacterial peptide from a coleopteran insect; member of defensin family; contains 74 amino acids; amino acid sequence given in first source
colgate sensitive: a dentifrice containing 5.0% potassium nitrate and 0.454% stannous fluoride
colicin 5 protein, E coli: isolated from e. coli; amino acid ; genbank x87835
colicin A lysis protein precursor, Bacteria: acetylated precursor form of the colicin a lysis protein; natural substrate of the degp protease
colicin E5 protein, E coli: a trna-targeting ribonuclease
colistinase: serine alkaline protease from bacillus polymyxa var. colistinus
colitose: rn given refers to (l-xylo)-isomer; see also records for paratose & tyvelose
colla corii asini: gelatin isolated from the hide of the donkey, equus asinus; used as a nutritional supplement and to treat a variety of conditions
collagen 4alpha3 chain (28-40), rat: can induce glomerulonephritis
collagen I, alpha chain (98-110): synthetic substrate for human protocollagen lysyl hydroxylase; rn given refers to tritium-labeled cpd
collagen II C-telopeptide: marker for collagen ii degradation in osteoarthritis
collagen XXVIII, mouse: developmentally regulated and forms thin fibrillar structures distinct from those of classical vertebrate fibrillar collagens
collagen fragment alpha1-CB7: cyanogen bromide fragment from stromal collagen; 271-amino acid residues; amino acid sequence given in first source
collagen telopeptidase: neutral metalloproteinase from porcine gingiva; removes the extra-helical extension peptides proximal to the lysyl residue at position 17
collagen tripeptide Ctp, human: non-antigenic, and low allergenic tripeptide fraction produced by collagenase digestion
collagen type I trimeric cross-linked peptide: contains trifunctional cross-linking amino acid pyridinoline; marker for alveolar bone loss; amino acid sequence &
collagen type II (108-116), (NO2)Tyr(111)-: marker of type ii collagen degradation
collagen type II (256-276), Asn(263), Asp(266)-: inhibits t cell responses associated with autoimmune arthritis
collagen type IV alpha1 (531-543): amino acid sequence given in first source; active in directly promoting keratinocyte adhesion
collagen-based sealant GAO: may be an effective biomaterial to prevent epidural adhesions in vivo after laminectomy
collagen-ferrous complex: metalloprotein formed from collagen and ferrous ion allows iron to enter the animal organism by well-known metabolic pathways
collagen-glycosaminoglycan copolymer: induces partial regeneration of adult mammalian skin
collagen-related peptide: a collagen receptor (gp)vi agonist; amino acid
collagenase activator protein, Bos taurus: bovine protein is acidic protein with metalloprotease activity, synthesized by articular cartilage
collagenase-like enzyme of adenohypophysis: acts on synthetic peptide substrates
collagenolytic protease I, crab: from the fiddler crab uca pugilator; belongs to the serine proteases of the trypsin family
collapsin response mediator protein-2: an intracellular protein related to nematode neuronal protein unc-33, from xenopus laevis oocytes; expressed selectively in developing nervous system; refseq nm_001105717 for dpysl2-rat
collectin-43 protein, bovine: a bovine serum protein with homology to bovine conglutinin; belongs to collectins (group iii of the c-type lectins); amino acid sequence given in first source; genbank x75912
collemin A: a photo protective mycosporine was isolated from the lichenized ascomycete collema cristatum; structure in first soure
colletoic acid: an 11beta-hydroxysteroid dehydrogenase type 1 inhibitor from colletotrichum gloeosporioides
colletotric acid: a tridepside, c28h28o10 from colletotrichum gloeosporioides
colletotrichin: phytotoxic metabolite of fungus colletotrichum nicotianae; inhibits respiratory chain
colligin: mw 47,000 cell surface associated glycoprotein; binds to both gelatin & collagen
colligrin protein, Streptococcus pneumoniae: localized to the cytoplasmic fraction from incompetent cells; has been sequenced; genbank l36131
collinemycin: from bohemic acid complex; cpd is (1s)-stereoisomer of musettamycin
collinusin: lignan lactone extract from highly poisonous plant cleitanthus collinus (roxb)
collismycin C: a microbial natural product first reported from streptomyces sp. sf2738, and it was identified to possess a characteristic 2,2'-bipyridine core
collocalia mucoid protein, Pelopidas sinensis: nest-cementing glycoprotein substance of chinese swift
collybistin II protein, mouse: a gephyrin-interacting guanine nucleotide exchange factor; has been sequenced
colnelenic acid: rn given refers to (e,e,z,z)-isomer
colombiasin A: isolated from the west indian gorgonian octacoral, pseudopterogorgia elisabethae
colombistatin, Bothrops colombiensis: isolated from the venom of the south american snake (bothrops columbiensis) that effectively inhibits platelet aggregation and sk-mel-28 cell adhesion
colominic acid: polymer of sialic acid in which the monomers are linked by an alpha-2,8-ketosidic linkage
colon cancer-specific antigen 2, human: a potential serum-based marker for colon cancer detection with high sensitivity and specificity
colon carcinoma monosialoganglioside antigen: antigen of a monoclonal antibody
colon-ovarian tumor antigen, human: found in mucins produced by both tissues during malignancy
colon-specific antigen: tumor marker for colon neoplasms; identified by a7 mab
colonization factor antigens: protein found on plasmid-mediated fimbriae from enteropathogenic strains of e coli; known to confer adhesive & colonizing properties for intestinal epithelium of several domestic animals & man to host strain; has been sequenced; genbank x97494
colony inhibiting factor: high mw protein or lipoprotein substances which are inhibitory to in vitro granulocyte colony growth; enhance capacity of macrophages to inhibit tumor cell proliferation
colopsinol D: a chitinase inhibitor, was isolated from the cultured broth of a fungal strain fo-7314.
colopsinol E: a chitinase inhibitor, was isolated from the cultured broth of a fungal strain fo-7314.
colopten: purified antigen fraction from staphylococcus aureus, escherichia coli, aerobacter aerogenes and proteus vulgaris
colorectal carcinoma-associated antigen, human: is probably a ckap4-like protein, belonging to deltanp63alpha isoform of p63 family
colorectal tumor-associated antigen, human: expressed at relatively comparable levels in colorectal and melanoma tumor cells, ebv-infected b cells, normal b cells, and cultured fibroblast cell lines; amino acid
colored collagen: a long-lasting point marker for small pulmonary nodules under thoracoscopy; composed of 0.8% atelocollagen, 10% methylene blue, and 32% iohexol dissolved in phosphate buffered saline (ph 7.4)
colossolactone B: antibacterial compound from the mushroom ganoderma colossum from nigeria
colossolactone E: antibacterial compound from the mushroom ganoderma colossum from nigeria
colossolactone H: isolated from the fruiting bodies of ganoderma colossum
colquhounoid A: from the peltate glandular trichomes of colquhounia coccinea var. mollis (lamiaceae); structrure in first source
colquhounoid B: from the peltate glandular trichomes of colquhounia coccinea var. mollis (lamiaceae); structrure in first source
colquhounoid C: from the peltate glandular trichomes of colquhounia coccinea var. mollis (lamiaceae); structrure in first source
columbianadin: furanocoumarin isolated from peucedanum palustre; rn given refers to columbianadin, (s-(z))-isomer
columbianetin acetate: from angelica pubescens; rn given refers to (s)-isomer; rn for cpd without isomeric designation not avail 9/92
columbianetin glucopyranoside: constituent of the chinese drug duhuo; the root of angelica pubescents
columbin: from tinospora cordifolia miers & calumbae radix (the root of jateorhiza columba miers, menispermacea)
columnaristerol A: has antineoplastic activity; isolated from the octocoral nephthea columnaris
colutehydroquinone: isolated from the root bark of colutea arborescens
colutellin A: an immunosuppressive peptide from colletotrichum dematium, an endophytic fungus recovered from a pteromischum sp. growing in a tropical forest in costa rica
comB protein, Haemophilus influenzae: dna transformation protein; amino acid sequence given in first source; involved in transformation (competence for dna uptake); do not confuse wtih 2-phosphosulfolactate phosphatase (comb phosphatase)
comC protein, Bacillus subtilis: type 4 prepilin-like proteins leader peptide processing enzyme; has prepilin peptidase (ec 3.4.23.43) as well as n-methyltransferase (ec 2.1.1.-) activities; amino acid sequence given in first source; may be a component of the dna-processing apparatus of competent cells; cleaves pre-comgc; homologous to pild protein; member of protease/transmethylase family; isolated from bacillus subtilis; do not confuse with comc, a peptide competence factor
comC-alpha protein, Enterobacteria phage T4: acidic protein of 141 residues; mw 22 kda; a possible transcription antitermination factor; amino acid sequence given in first source
comF1 protein, Bacillus subtilis: amino acid sequence given in first source; a late competence protein required for dna uptake; related to a family of atp-dependent rna/dna helicases
comF3 protein, Bacillus subtilis: amino acid sequence given in first source; a competence protein
comK protein, Bacillus subtilis: required for genetic compentence of bacillus subtilis; amino acid
comL protein, Neisseria gonorrhoeae: peptidoglycan-linked lipoprotein that is involved in natural transformation competence of neisseria gonorrhoeae; homologous counterparts of the coml gene are found in neisseria meningitidis as well as in several nonpathogenic neisseria species; genbank z49895
comP protein, Bacillus subtilis: sensor protein; activates coma protein, by phosphorylation; from bacillus subtilis; may also play a role in sporulation of spoiij; amino acid sequence given in first source; do not confuse with cartilage oligomeric matrix protein
comQ protein, Bacillus subtilis: from bacillus subtilis; mw 34 kda; required for the processing, modification, and release of active competence; amino acid sequence given in first source
comastomasaponin I: nitric oxide production inhibitor from the aerial portions of comastomapedunculatum
comastomasaponin J: nitric oxide production inhibitor from the aerial portions of comastomapedunculatum
comastomasaponin K: nitric oxide production inhibitor from the aerial portions of comastomapedunculatum
combiferon: contains leukocytic interferon alpha & recombinant interferon alfa 2 (reaferon)
combotox: a 50:50 mixture of two ricin-conjugated antibodies, rfb4 and hd37; has antineoplastic activity
combretastatin: cytotoxic principle from south african tree combretum caffrum; ; acts at colchicine site of tubulin
combretastatin A-2: isolated from combretum caffrum; rn from first source
combretastatin A5: inhibits growth of neisseria gonorrhoeae; rn given refers to combretastatin a5 ((z)-isomer); combretastatin a6 is the (e)-isomer
combutec: russian drug; no other information available 1977; "collagen base" of trophic ulcers (venous)
comenic acid: an ingredient of baliz-2 that may have antibacterial and antioxidant activities
comm protein, Drosophila: controls axon crossing of the cns midline and robo expression; has been sequenced; refseq nm_079371
common chronic lymphatic leukemia antigen gp69, human: expressed by monoclonal cells in patients with chronic lymphatic leukemia, b-prolymphocytic leukemia & b-hairy cell leukemia; mw 69kda
common salivary protein 1, rat: from submandibular, sublingual & parotid glands; refseq nm_133622
communesin B: from ethyl acetate extract of penicillium sp., derived from the mediterranean sponge axinella verrucosa
communesin C: from ethyl acetate extract of penicillium sp., derived from the mediterranean sponge axinella verrucosa
communesin D: from ethyl acetate extract of penicillium sp., derived from the mediterranean sponge axinella verrucosa
communesin E: has insecticidal activity against silkworms; isolated from penicillium expansum
communesin G: alkaloid from the psychrotolerant fungus penicillium rivulum
communesin H: alkaloid from the psychrotolerant fungus penicillium rivulum
comosone A: cytotoxic compound from the brown alga sporochnus comosus
compact-colony-forming active substance: blood-clotting polysaccharide from staph aureus different from staphylocoagulase & clumping factor
complement 1q receptor: an acidic, mitochondrial matrix protein; may bind protein kinase c; aa4 is murine homologue; refseq nm_012072 (human), nm_010740 (mouse), nm_053383 (rat)
complement 4 nephritic factor: auto-antibody which stabilizes the classical pathway c3 convertase, c4b2a complex
complement C1 inhibitor Ta: a dysfunctional complement c1 inhibitor protein (c1inh) with deletion of lysine 251 found in patients with hereditary angioedema; this results in acquisition of an n-glycosylation site
complement C2, C allele protein: a variant of complement c2 protein, encoded by the c allele of c2 gene
complement C3a receptor: mammalian anaphylatoxin c3a receptor; refseq nm_004054 (human); nm_009779 (mouse); nm_032060 (rat)
complement C3a, (57-77): a peptide of 21-amino acids at the carboxy-terminal of complement 3a; causes thromboxane-dependent pulmonary vascular constriction in isolated perfused rat lungs
complement C3a, (70-77): synthetic octapeptide which retains anaphylatoxin activity
complement C3a, (72-77): the 6-amino-acid c-terminal peptide of human c3a; with anaphylatoxin activity; stimulates arachidonic acid metabolism and thromboxane release from macrophages
complement C3a, des-Arg-(77)-: c3a without the cooh-terminal arginine at the 77-position; also known as the acylation-stimulating protein or asp; a paracrine signal to increase triglyceride synthesis in adipocytes
complement C3bBa complex: ba, mw 30-kda; normally, ba has low affinity for c3b; this c3bba complex was prepared by the use of the cross-linking reagent dithiobis (succinimidyl propionate)
complement C3d,g: mw 41,00 single polypeptide biologically active fragment of c3b cleaved by c3b inactivator enzyme
complement C3d-k: a 43-kda cleavage product of complement c3b; generated from the alpha chain of human ic3b by limited proteolysis with kallikrein; resembles the c3d,g fragment; induces leukocytosis
complement C3e: mw of 10-12,000; an acidic fragment of complement c3b; generated from the alpha chain of c3b; binds to granulocyte membrane; similar to complement c3d-k, c3e contains the nonapeptide thr-leu-asp-pro-glu-arg-leu-gly-arg and induces leukocytosis
complement C3f: a 17-amino acid fragment of complement c3b; derived from the alpha chain of c3; a weak spasmogen that functions like c3a anaphylatoxin
complement C3f-des-arginine: derived from c3b, involved in the pathophysiologic mechanisms of systemic sclerosis
complement C3g: pa 47-amino acid fragment of complement 3b; a breakdown product derived from the alpha chain of c3; do not confuse with c3g protein, a carrier protein
complement C4A7: variant of complement 4; human c4 is coded for by two separate but closely linked loci (c4a and c4b) on chromosome 6; the c4 genes are highly polymorphic with more than 30 alleles
complement C4c: a degradation product of c4b; c4b is cleaved by c4b/c3b inactivator (complement factor i) to yield c4d and c4c
complement C4d: a degradation product of c4b; c4b is cleaved by c4b/c3b inactivator (complement factor i) to yield c4d and c4c
complement C5a, (65-74), Tyr(65)-Phe(67)-Pro(69,71)-Ala(73)-: decapeptide agonist of human c5a; with substitutions in the c-terminal sequence (65-74)
complement C5a-inhibitors: found in normal peritoneal & synovial fluids; deficiency causes familial mediterranean fever; also found in streptococcus; have capability of inactivating complement-derived chemotactic factors; do not use /antag
complement C5b-6 complex: a biomolecular complex; formed by the binding of c6 to c5b during the cascade of complement activation; rn given in first source
complement C5b-7 complex: a trimolecular complex; generated from the binding of c7 to the bimolecular complex c5b6 during the cascade of complement activation; soluble c5b-7 is the complex of c5b-7 and vitronectin (complement s-protein)
complement C5b-8 complex: the complement complex containing c5b, c6, c7, and c8; generated during the cascade of complement activation; it catalyzed the assembly of poly-c9 to form the membrane attack complex or c5b-p9
complement C9 polymer: polymerized complement c9; tubular 27s complex forming the transmembrane channel of the membrane attack complex; mw 1,050,000 +/- 40,000; see also record for complement membrane attack complex
complement C9b: a fragment of complement c9; thrombin cleaves c9 to produce two attached fragments, the n-terminal c9a (244 amino acids) and the c-terminal c9b (294 amino acids)
complement activation blocker 2, human: a recombinant soluble chimeric complement inhibitor composed of human cd46 and cd55 reduces acute cardiac tissue injury; may represent a useful therapeutic agent for xenotransplantation and other complement-mediated conditions
complement regulator-acquiring surface protein-1, Borrelia hermsii: involved in the dissemination/invasion of b. hermsii and its resistance to innate immunity; genbank am408562
complement regulator-acquiring surface proteins, Borrelia burgdorferi: surface proteins of borrelia burgdorferi
complement regulatory protein, Trypanosoma cruzi: functions in a similar manner as members of a family of mammalian regulators of c3 convertase; mw 160 kda; amino acid sequence given in first source; genbank u59297
complement-control protein, Vaccinia virus: amino acid sequence has been determined; secreted from infected cells; has sequence similarities to members of a gene family that includes complement control proteins
complementary PR3 (138-169), human: causes t-cell responsiveness; derived from cpr3, encoded by antisense rna to pr3
complementary human autoantigen proteinase-3 (105-201): a recombinant antisense pr-3 peptide that triggers autoimmunity
complestatin: compound extracted from streptomyces lavendulae mycelia; on acid hydrolysis yields d-4-hydroxyphenylglycine & d-3,5-dichloro-4-hydroxyphenylglycine & acidic chromophore; inhibits gp120-cd4 binding
complex V (mitochondrial oxidative phosphorylation system): consists of the 5 subunits of f1-atpase; oligomycin sensitivity-conferring protein, uncoupler-binding protein, dicyclohexylcarbodiimide-binding protein, a membrane sector protein, & coupling factor f(6)
complexin I: regulates snap receptor function during membrane fusion; shows 84% homology with complexin ii; amino acid sequence given in first source
complexin II: regulates snap receptor function during membrane fusion; shows 84% homology with complexin i
component S, glutamate mutase protein, Bacteria: component s of the coenzyme b12-dependent glutamate mutase from clostridium cochlearium; mw 15 kda; amino acid sequence given in first source
compositus Yiqi Huoxue: no other info available 1/12/81
compound 183: 5-bromotubercidin in which the ribose moiety has been replaced by a 1,3-dihydroxypropoxymethyl moiety
compound 1929: derivative of 5-alkyl-3h-furanone; no other info avail 6/90
compound 2-5410-4A: ; a non-ionic dimeric ratio 6 contrast medium used in urography; analog of iodixanol
compound 20: amide bond between phe-gly of tripeptide replaced with ketomethylene
compound 2065-14: has antinociceptive activity; binds both delta and kappa opioid receptors
compound 371196: a protein kinase c-beta inhibitor; an analog of ly-333531
compound 5.4: pregnenolone isomer with gas chromatographic retention time of 5.4 min
compound 72-70: antifilarial 1-substituted-4-carbamoylpiperazine; no other info available 1/9/84
compound A (octyltriazole): a 4-heteroarylbicyclo(2.2.2)octyltriazole compound, specific compound structure and chemical name not revealed in first citation
compound B 40: derivative of phenylimidazothiazole group; no other info available 7/89
compound C4 (Crassin): a diterpenoid natural compound; has cytostatic effect on triple-negative breast cancer cells
compound E (Friedheim): reaction product of f 151, an arsenical & hoe 33258 in 1:2 molar ratio, respectively
compound W: a 3,3'-diiodothyronine sulfate-like material in serum of pregnant women; a potential marker for fetal thyroid function
comr protein, Drosophila: a meiotic arrest gene product localized to the nucleus of primary spermatocytes; refseq nm_137773
conZA7 protein, Euplotes crassus: a conjugation-specific protein from ciliate euplotes crassus; amino acid sequence given in first source; genbank u65975
conZA8 protein, Euplotes crassus: from ciliate euplotes crassus; amino acid
cona protein, Drosophila: required for the polymerization of c3g protein to yield filaments for the central region of the synaptonemal complex; has been sequenced; refseq nm_142462
conantokin ET: all gamma-carboxyglutamic acid (gla) residues in conantokin-t are replaced by glutamic acid
conantokin-Br, Conus brettinghami: aa seq in first source; isolated from from conus brettinghami; has a high potency for nmda receptors with nr2d subunits
conantokin-E: member of a family of conus venom peptides that are n-methyl-d-aspartate (nmda) receptor antagonists; from fish-hunting cone snails, conus purpurascens and conus ermineus; 24 amino acid residues
conantokin-L: isolated from the deep-water conus lynceus; amino acid
conantokin-P: member of a family of conus venom peptides that are n-methyl-d-aspartate (nmda) receptor antagonists; from fish-hunting cone snails, conus purpurascens and conus ermineus; 24 amino acid residues
conantokin-T: from cone snail conus tulipa; a 21-amino acid peptide which induces sleep-like symptoms in young mice; has n-methyl-d-aspartate antagonist activity; amino acid sequence given in first source
conarachin I protein, peanut: one of two major globulins in peanut (other is arachin)
concanamycin A: from streptomyces diastatochromogenes s-45; inhibits vacuolar h+ atpase
concanamycin B: from streptomyces diastatochromogenes s-45
concanamycin C: from streptomyces diastatochromogenes s-45
concanamycin D: from streptomyces sp. a1509; inhibitor of lysosomal acidification
concanamycin E: from streptomyces sp a1509; inhibitor of lysosomal acidification
concanamycin F: from streptomyces sp. a1509; inhibitor of lysosomal acidification
concanamycin G: from streptomyces sp. a1509; inhibitor of lysosomal acidification
concanavalin A conjugated bleomycin: prepared for purpose of enhancing activity of bleomycin
concanavalin A-O-(diethylaminoethyl)cellulose: affinity label for glycoproteins which interact with con a
concanavalin A-gold: a lectin-gold complex used as an endocytic tracer
conchitriol: from sideritis species, protects astrocytes against oxidative stress via nf-e2-related factor 2
concizumab: blocked the interaction between fxa and factor pathway inhibitor in a rabbit hemophilia model
condaline-A: was isolated from the root bark of condalia buxifolia reissek (rhamnaceae)
condensin complexes: condensin 13s is the holocomplex; fosters atp-dependent right-hand wrapping of dna; amino acid
conduritol B: rn given for ((1alpha,2beta,3alpha,4beta)-(+-))-isomer
cone rod homeobox protein: an otx-like gene with photoreceptor-specific expression that regulates photoreceptor differentiation
confertifolin: isolated from the essential oil of polygonum hydropiper (polygonaceae) leaves
confluentin: prenylphenol from basidiocarps of european and chinese albatrellus spp.
congerin II protein, Conger eel: isolated from the skin mucus of conger eel, conger myriaster; amino acid
congerin protein, Conger myriaster: from conger eel, amino acid sequence given in first source; a 30 kda beta-galactoside-binding lectin isolated from the skin mucus of conger eel, conger myriaster
conglutin-gamma protein, Lupinus angustifolius: amino acid sequence given in first source; a sulfur-rich protein from lupinus angustifolius
conglutinin: non-immunoglobulin protein, bovine & newborn pigs
congopain: 33 kda cysteine protease from trypanosoma congolense
conidendrin: rn given for (3ar-(3aalpha,4alpha,9alpha,9abeta))-isomer; a phenyl-naphthyl-furanolactone
conidiogenone H: from a marine-derived endophytic fungus penicillium chrysogenum qen-24s
conidiogenone I: from a marine-derived endophytic fungus penicillium chrysogenum qen-24s
coniferyl 9-O-(beta-D-apiofuranosyl(1-6))-O-beta-D-glucopyranoside: from the seeds of punica granatum (pomegranate)
coniferyl alcohol dehydrogenase: leads to the formation of the monomers of lignins, requires nadp+
coniferyl aldehyde dehydrogenase: catalyzes nad+-dependent oxidation of coniferyl aldehyde to ferulic acid
coniferyl ferulate: found in the rhizome of cnidium officinale makino; ; rn given refers to cpd without isomeric designation
coniferyl-alcohol glucosyltransferase: forms the 4-o-beta-d glucoside, coniferin
coniferyl-alcohol oxidase: converts coniferyl alcohol to dehydrodiconiferyl alcohol and pinoresinol, intermediates in the formation of lignin in pine trees; requires o2
coniine: alkaloid isolated from conium maculatum l.; properties as an analgesics, antineuralgic, & teratogen; rn given refers to parent cpd without isomeric designation
coniochaetone H: from the cordyceps-colonizing fungus fimetariella sp.
coniofurol A: from the endolichenic fungus coniochaeta sp.; structure in first souce
conioidine A: ; isolated from chamaesaracha conioides; binds to dna
conioidine B: ; a dna-binding compound from chamaesaracha conioides
coniothyren: from the endophytic fungus, coniothyrium sp.
coniothyriomycin: rn given for (e)-isomer; has antifungal activity
conioxanthone A: from the endolichenic fungus coniochaeta sp.; structure in first souce
conjunctisan A: consists of proteins, amino acids, extracts of retina, cornea, & nerves of the eye; used in treatment of cataract and other degenerative eye disorders
conjuvac: conjugate of allergenic protein from dermatophagoides pteronyssinus & sodium alginate
conkunitzin-S1, Conus striatus: 60-residue neurotoxin from the venom of the cone snail conus striatus that interacts with voltage-gated potassium channels; member of a kunitz-type neurotoxin family; databank pdb/1yl2
connatusin A: hirsutane sesquiterpene from the fungus lentinus connatus
connatusin B: hirsutane sesquiterpene from the fungus lentinus connatus
connective tissue-activating peptide: slightly basic saline soluble polypeptide extractable from many tissues; induces hypermetabolic activity in cultivated human synovial cells 10,000-15,000
connexin 30.3: gap junction gene product found on chromosome 4 & preferentially expressed in skin
connexin 31.1: gap junction gene product found on chromosome 4 & preferentially expressed in skin
connexin 35 protein, vertebrate: isolated from the retina of the skate raja and other vertebrates; genbank u43290 (skate)
connexin 39 protein, mouse: is expressed in developing striated muscle fibers; has been sequenced
connexin 40.4 protein, Xenopus: expressed in somites; genbank ay792358
connexin 45: was sy to gap junction protein (nm); use connexins (nm) to search through 1993; rn given is for reduced chicken connexin
connexin 50: mw 70,000; found in lens fiber 16-17-nm intercellular junctions
conocarpan: rn given for (2r-(2alpha,3beta,5(e))-isomer; from the roots of krameria tomentosa (krameriaceae)
conocurvone: a trimeric naphthoquinone derivative; extracted from conospermum incurvum
conodipine M: a phospholipase a2; isolated from the venom of the marine snail conus magus; mw 13.6 kda; partial amino acid sequence given in first source
conoideocrellide A: from the scale insect pathogenic fungus conoideocrella tenuis
conolidine: analgesic from the stem bark of tabernaemontana divaricata
conolutinine: reverses multidrug resistance in vincristine-resistant kb cells, isolated from malaysian tabernaemontana
conolysin-Mt, Conus mustelinus: a membrane-disrupting peptide; amino acid
conomarphin, Conus marmoreus: a d-amino acid-containing conotoxin; amino acid
conopharyngine: from tabernamontana pachysiphon stapf. var cumminsii (staph.) h. huber
conopharyngine pseudoindoxyl: from tabernamontana pachysiphon stapf. var cumminsii (staph.) h. huber
conophylline: isolated from the leaves of ervatamia microphylla; a ras function inhibitor
conophysin-R, Conus radiatus: the distinctive disulfide framework and sequence indicates that it is a member of the neurophysin peptide family; mw 8810.89 da; sequence of the peptide is hptkpcmycsfgqcvgphiccgptgcemgtaeanmcseededpipcqvfgsdcalnnpdnihghcvadgiccvddtctthlgcl, in first source
conorfamide-Sr3: isolated from the venom of conus spurius; peptide sequence atsgpmgwlpvfyrf-nh2
conorphin-1 peptide: a synthetic peripheral kappa opioid receptor agonist with analgesic activity
conotoxin AuIB: a nicotinic acetylcholine receptor (nachr) with putative alpha3 beta4-subunits
conotoxin EI: a nicotinic acetylcholine receptor (nachr) ligand; from conus ermineus venom; an 18 amino acid peptide; amino acid sequence given in first source
conotoxin GI: highly toxic; from venom of marine snail conus geographus; amino acid sequence given in first source
conotoxin GI, des-Glu(1)-: rn given refers to (l-glu)-isomer; amino acid seq given in first source
conotoxin GIA: highly toxic; from venom of marine snail conus geographus; amino acid sequence given in first source
conotoxin GII: highly toxic; from venom of marine snail conus geographus; amino acid sequence given in first source
conotoxin GIII: discriminate between neuronal & muscle sodium channels; from conus geographus
conotoxin GIV: heat stable acidic protein from venom of marine snail conus geographus linne; has apparent monomer mw of 13,000; potent convulsant following intracerebral injection
conotoxin GS: from conus geographus; contains 34 amino acid residues; amino acid sequence given in first source
conotoxin MI: 14-residue peptide toxin from marine snail conus magus; amino acid
conotoxin MrVIA: from the venom of conus marmoreus; amino acid sequence given in first source
conotoxin MrVIB: from the venom of conus marmoreus; amino acid sequence given in first source
conotoxin NgVIA: from conus nigropunctatus; amino acid sequence given in first source
conotoxin Qc1.2, Conus quercinus: alpha 4-4-conotoxin; calcium channel blocker from vermivorous conus quercinus
conotoxin SI: from conus striatus; blocks nicotinic acetylcholine receptors; amino acid sequence given in first source
conotoxin TVIIA: peptide from the venom of conus tulipa; amino acid
conotoxin TxVI, Gla(1)-: isolated from conus textile; amino acid
conotoxin TxVIA: selectively toxic to molluscs & slows sodium current inactivation in mollusc neurons; binds with high affinity to new sites on sodium channels in both mollusc & rat central nervous systems
conotoxin alpha-RgIA, Conus regius: blocks alpha9 and alpha10 nicotinic acetylcholine receptor subunits; amino acid
conotoxin gm9a, Conus gloriamaris: genbank af193511
conotoxin mr3a, Conus marmoreus: from the venom of conus marmoreus, a peptide that induces rolling seizures in mice & has the peptide sequence gccgsfacrfgcvoccv, where o is trans-4-hydroxyproline
consanguine B: has antineoplastic activity; isolated from polyalthia obliqua
consortin protein, mouse: a cargo receptor expressed in golgi and plasma membranes; refseq nm_146105
constatin (1-89): derived from the noncollagenous 1 domain of the alpha2 chain of type iv collagen
constitutive differential growth 1 protein, Arabidopsis: a receptor-like cytoplasmic kinase; refseq nm_113608
contortin: polymeric, helical structure from protein fraction of adult haemonchus contortus used for immunizing young lambs
contortrostatin: a homodimeric disintegrin that binds to integrin alphavbeta5
contraception associated protein 1: putative dj-1 homolog; isolated from rat; amino acid ; genbank aj007291
contractin A: amino acid sequence has been determined; from the pedicellarial venom of sea urchi; causes histamine release from mast cells
contramutan N: consists of eupatorium aconitum, echinacea, belladonna; for treatment of grippe
contrast agent BR1: consists of microbubbles containing sulfur hexafluoride stabilized by phospholipids
contrast agent P792: a gadolinium macrocyclic compound based on a gd-dota structure substituted by hydrophilic arms; rapid clearance blood pool agent for magnetic resonance imaging
contulakin-G protein, Conus geographus: an invertebrate neurotensin isolated from conus geographus venom; genbank af121108
conulin: a grasshopper protein; secreted from neuronal growth cones; mw 190 kda; recognized by monoclonal antibody 7d2
convallamaroside: steroidal saponin from the rhizomes and roots of convallaria majalis l with anti-angiogenic activity
convallasaponin A: a 5beta-spirostanol triglycoside from the rhizomes of convallaria majalis
convalloside: neoconvalloside is the stereoisomer of convalloside; rn refers to (3beta,5beta)-isomer
convolutamine H: brominated alkaloid from the marine bryozoan amathia convoluta
convolutindole A: brominated alkaloid from the marine bryozoan amathia convoluta
convolvulin: sedative, vasorelaxant, and cytotoxic resin glycoside from roots of ipomoea tyrianthina
convulxin: component of venom from crotalus durissus cascavella which activates guinea pig platelets; consists of glycoprotein built up of alpha & beta subunits; similar to ophioluxin
conyzoflavone: has both antifungal and antibacterial activities; isolated from conyza canadensis
conyzolide: has both antifungal and antibacterial activities; isolated from conyza canadensis
cooliatoxin: a toxin from the benthic dinoflagellate coolia monotis; its molecular weight corresponds to the mono-sulfated form of yessotoxin
cop protein, Bacteria: replication protein of plasmid pe194; involved in the copy number control of plasmid pe194; amino acid sequence known
cop-2 protein, Haloarcula japonica: a light-driven proton pump from haloarcula; 255 amino acids, mw 27.5 kda; 77% homologous to cruxrhodopsin-1; amino acid sequence given in first source
copaiba balsam: a phytogenic antineoplastic agent; isolated from copaifera langsdorffii
copaiba oleoresin: vaginal cream containing copaiba oil (copaifera duckei dwyer)
copalol: rn given for (1r-(1alpha(e),4abeta,8aalpha))-isomer
copeptins: glycopeptide third domain of vasopressin precursor along with msel-neurophysin; 39 amino acid residues in most mammalian species, 38 in guinea pig; amino acids vary somewhat among species
copine: belongs to a class of c2 domain-containing, calcium-dependent, phospholipid-binding proteins conserved from protozoans to humans; amino acid
copine III: a phosphoprotein with associated kinase activity; amino acid ; genbank af077226
copoly(allylamine-N1,N3-diallylpropane-1,3-diamine)acetate: a cross-linked, phosphate-binding polymer
copoly(aspartic acid-glutamic acid): rn given refers to parent cpd all (l)-isomer
copper (II) 3-hydroxy-1-(4-phenylsulfonic acid)-3-phenyltriazene: ; used for analysis of copper in biological samples
copper (II) diacetyl-di(N(4)-methylthiosemicarbazone): a stable superoxide dismutase-like copper complex; a hypoxia imaging agent that scavenges peroxynitrite and has neuroprotective activity
copper (II) ethylglyoxal bis(N(4)-methylthiosemicarbazone): considered as pet tracer
copper (II) pyruvaldehyde bis(N(4)-dimethylthiosemicarbazone): considered as pet tracer
copper 1,4,8,11--tetraazacyclotetradecane-N,N',N'',N'''-tetraacetic acid-octreotide: a pet imaging agent
copper 2,2'-bicinchoninate: reagent for determining uric acid in blood
copper 4,11-bis(carboxymethyl)-1,4,8,11-tetraazabicyclo(6.6.2)hexadecane-ReCCMSH(Arg(11)): a cross-bridged cyclam chelator
copper acetamidobenzyl-1,4,8,11-tetraazacyclotetradecane-N,N',N'',N'''-tetraacetic acid-serum albumin: radiopharmaceutical; can belabeled with copper-62
copper acetyl-histidyl-glycyl-glycyl-glycinamide: interacts with nitric oxide; based on prion protein octa-repeat region
copper acetyl-phenylalanyl-histidyl-glycyl-glycyl-glycyl-tryptophyl-glycyl-glutaminamide: interacts with nitric oxide; based on prion protein octa-repeat region
copper bis(3,5-diisopropylsalicylate): copper is intricate part of molecule; not copper salt; rn given refers to cpd with specified locants for methylethyl moieties
copper bis(histidinate): rn given refers to n,n(3),o(l)-isomer
copper diethylamine oxyquinoline sulfonate: copper complex to alleviate hypocupraemia in sheep & cattle
copper naphthenate: fungitrol is a cu naphthenate fungicide normally used to protect fibrous substrates
copper perbromophthalocyanine: structure showing bond distances & angles given in first source
copper phthalocyanine tetrasulfonic acid: ; rn given refers to tetrahydrogen cpd
copper phthalocyanine trisulfonic acid: rn given refers to tri-na salt
copper salicylate complex: copper(ii)-salicylate complex in ethanol with glycerol; suppressed established polyarthritis, carrageenan-induced paw oedema & inflammatory response to hydroxyapatite crystals; possibly due to synergism between salicylate & copper(ii); rn given for cupric salicylate in merck; merck reference for cupric salicylate
copper tetra-aminophthalocyanine-Fe3O4: a magnetic nanoparticle composite
copper tetrabenzo(b,f,j,n)-1,5,9,13-tetraazacyclohexadecine: catalytic reagent for oxidation of ascorbic acid; rn given refers to dinitrate
copper tetrakis(3,5-diisopropylsalicylic acid): ; not a copper salt
copper thionein: formed from metallothionein by reaction with copper; not the same as thioneine (an ergot alkaloid); genbank k02204 (cup1-1)
copper(I)-tris(thiourea): rn given refers to (sulfate[2:1]salt)
copper(II) (2,3-butanedionebis(N(4)-methylthiosemicarbazone)): a superoxide dismutase-like drug
copper(II) 5,10,15,20-tetrakis(alpha,alpha,alpha,alpha-2-(2,6-bis(4-methylpiperazine-1-ylmethyl)-4-iminomethylphenol)phenyl)porphyrin: has anti-inflammatory activity
copper(II)(1,10-phenanthroline)3: catalyzes disulfide formation
copper(II)-N,N,N',N',N'',N''-hexakis(2-pyridyl)-1,3,5-tris(aminomethyl)benzene: trinuclear copper(ii) complex
copper(II)-iminodiacetate: catalyzes hydrolysis of alpha-amino acid esters
copper(II)-methyl 2-(2-aminoethyl)aminoethylpyridine-6-carboxylhistidinate: synthetic analog of chelating part of bleomycin
copper-64-DOTA-NR-LU-10: possible antineoplastic agent
copper-67-2IT-BAT-Lym-1: a copper-67 radiopharmaceutical; lym-1 is murine anti-lymphoma igg2a antibody
copper-neocuproine complex: rn given refers to cu(ii) complex with unspecified stereochemistry
copper-thiosemicarbazone complex: structure & synthesis given in first source; causes dna strand scission
copperhead venom procoagulant enzyme: from copperhead venom; results in release of fibrinopeptide b from fibrinogen
coprisamide A: from a gut bacterium of the dung beetle copris tripartitus
coprisamide B: from a gut bacterium of the dung beetle copris tripartitus
coprisin peptide, Copris tripartitus: has antimicrobial activity; isolated from the korean dung beetle
coproporphyrin I: rn given refers to cpd with specified locants; see also record for coproporphyrin iii; zinc coproporphyrin i is fluorescent and a characteristic component of meconium
coproporphyrin III: rn given refers to unlabeled parent cpd; see also record for coproporphyrin i
coprostanone: bacterial metabolite of cholesterol via coprostanol; rn given refers to cpd without isomeric designation
cor tmc-ap3 protein, Hordeum vulgare: a chloroplastic amino acid selective channel protein correlated to cold acclimation in cereals; amino acid ; genbank aj011921
corA protein, Medicago sativa: cold & draught regulated protein in alfalfa (medicago sativa); a putative glycine-rich protein; amino acid sequence has been determined; genbank l03708
cora protein, Drosophila: required for septate junction integrity in drosophila; a member of the protein 4.1 superfamily; amino acid
corallidictyal A: a spirosesquiterpene aldehyde; from a marine sponge siphonodictyon coralliphagum; rn refers to corallidictyal a
corallidictyal D: originally from a marine sponge siphonodictyon coralliphagum
corallolide A: isolated from the caribbean gorgonian octocoral pseudopterogorgia bipinnata collected near providencia island, colombia
corallolide B: isolated from the caribbean gorgonian octocoral pseudopterogorgia bipinnata collected near providencia island, colombia
corallorazine A: from the myxobacterium corallococcus coralloides
corallorazine B: from the myxobacterium corallococcus coralloides
corallorazine C: from the myxobacterium corallococcus coralloides
coralmycin A: potent antibacterial from myxobacteria, corallococcus coralloides m23
coralmycin B: potent antibacterial from myxobacteria, corallococcus coralloides m23
coralyne: rn given refers to parent cpd; at this time it is not known for which salt nsc-154890 is synonym; structure; dna topoisomerse antagonist
coramsine: chemotherapeutic mixture of glycoalkaloids (solamargine and solasonine) from solanum linnaeanum (devil's apple)
corazonin protein, insect: cardioactive peptide; isolated from a variety of insects
corchoionoside C 6-O-sulfate: isolated from sonchus erzincanicus
corchorusin D: rn given refers to (3beta,16beta, all-d)-isomer; rn from ca index guide; isolated from cochorus acutangulus
cordacin: anti-leukemic substance isolated from drymaria cordata (l.) willd
cordatin: rn given for (2s-(2alpha,4abeta,6abeta,7beta,10aalpha,10bbeta))-isomer; isolated from aparisthmium cordatum
cordatolide A: rn given for the ((10alpha,11beta,12alpha)-(+))-isomer, which is cordatolide a; the rr refers to cordatolide b
cordiaquinol I: antileishmanial compound from cordia fragrantissima collected in burma (myanmar)
cordiaquinol J: antileishmanial compound from cordia fragrantissima collected in burma (myanmar)
cordiaquinol K: antileishmanial compound from cordia fragrantissima collected in burma (myanmar)
cordifene: isolated from leaves of erlangia cordifolia; has an alpha-methylene lactone group & a conjugated side chain ester; increases myometrial contractile activity
cordifoliketones A: phenylpropanoid isolated from the root codonopsis cordifolioidea (tsoong); has anti-hiv activity and cytotoxic activity against tumor cells
cordycepol C: has antineoplastic activity; isolated from cordyceps ophioglossoides
cordycommunin: antimycobacterial from the entomopathogenic fungus ophiocordyceps communis bcc 16475
cordyformamide: from the insect pathogenic fungus cordyceps brunnearubra
cordyheptapeptide B: from cordyceps sp. strains bcc 16173 and bcc 16176
cordyheptapeptide C: cytotoxic, from the marine-derived fungus acremonium persicinum scsio 115
cordyheptapeptide D: cytotoxic, from the marine-derived fungus acremonium persicinum scsio 115
cordyheptapeptide E: cytotoxic, from the marine-derived fungus acremonium persicinum scsio 115
cordymin: an antifungal peptide from the medicinal fungus cordyceps militaris
cordypyridone A: from the insect pathogenic fungus cordyceps nipponica
cordypyridone B: from the insect pathogenic fungus cordyceps nipponica
cordypyridone C: from the insect pathogenic fungus cordyceps nipponica
cordypyridone D: from the insect pathogenic fungus cordyceps nipponica
cordysinocan: isolated from cultured cordyceps (fungi), activates immune responses in cultured t-lymphocytes and macrophages: signaling cascade and induction of cytokines
cordysobin protein, Cordyceps sobolifera: inhibits hiv-1 reverse transcriptase
core 1 beta1,3-galactosyltransferase, Drosophila: catalyzes transfer of galactose from udp-gal to tn antigen to make t antigen; has been sequenced
core 4 beta1,6 N-acetylglucosaminyltransferase, human: epidermal growth factor (egf) suppressed c4gnt activity in human airway adenocarcinoma cell line
core binding factor alpha: core binding factor plays a key role in several development pathways and in human disease; has been sequenced
core endotoxin: portion of bacterial outer membrane lipopolysaccharide common to many gram-negative microorganisms
core protein p22, Hepatitis C virus: highly similar to hepatitis b virus core protein but posseses 10 additional amino acids
core protein p24, bovine leukemia virus: mw 24 kda; amino acid sequence has been determined
core protein, Sindbis virus: a chymotrypsin-like serine proteinase involved in the assembly of nucleocapsid; partial amino acid sequence given in first source
core protein, human: corresponds to a sequence within the transmembrane domain of the alpha chain of the t cell antigen receptor; amino acid
core protein, mouse: corresponds to a sequence within the transmembrane domain of the alpha chain of the t cell antigen receptor; amino acid
core-specific lectin: synthesized & secreted by rat hepatocytes & the rat hepatoma cell line, h-4-ii-e; binds mannose & n-acetylglucosamine residues in the core region of asn-linked oligosaccharides
coreoside E: linear c14 polyacetylene glucoside with antiadipogenic activities fom the capitula of coreopsis tinctoria
corexit 9500: could result in either increases or decreases in the toxicity of residual oil through selective microbial mineralization of hydrocarbons
corianin: rn given refers to 2as-(2aalpha,3alpha,6alpha,6aalpha,6bbeta,7abeta,7balpha,7calpha,8s*)-isomer
coriarioside A: oleanane-type saponin from the roots of albizia coriaria
coriarioside B: oleanane-type saponin from the roots of albizia coriaria
corin protein, rat: from heart; corin gene has reduced expression in experimental heart failure; genbank ay251285
coriolan: polysaccharide from coriolus versicolor composed of 1-2 or 1-6 linked glucopyranose residues
coriolin: sesquiterpene antibiotic isolated from coriolus consors; structure in third source
cormycin A: a lipodepsipeptide isolated from pseudomonas corrugata; amino acid
corn protein, Drosophila: binds inscuteable protein and microtublues; refseq nm_079230
corneal protein 11-24kDa, bovine: a water-soluble protein from bovine corneal epitheium; associated with corneal protein bcp54, but not as highly conserved
corneal protein 54, bovine: most soluble protein of bovine cornea; mw 54,000; constitutes 30% of the total soluble protein of whole cornea
corneodesmosin protein, mouse: a corneodesmosome extracellular protein; has been sequenced
cornifelin protein, mouse: contains 112 amino acids and is expressed in the uterus, cervix, and skin; has been sequenced
cornin peptide: growth substance isolated from adult animal tissues (bovine liver in this instance) containing inorganic substances, polypeptides & nucleotides; do not confuse with the other cornin which is a monoterpene iridoid
cornuside: a bisiridoid glucoside from cornus officinalis sieb et zucc
cornusiin B: isolated from cornus officinalis; rn from ca index guide 1989
corolla protein, Drosophila: contributes to the architecture of the synaptonemal complex
coromandelin: an isoflavone apioglucoside from the leaves of dalbergia coromandeliana
coronafacic acid: a polyketide that is coupled to coronamic acid by coronafacate ligase to form coronatine; ; rn refers to (3as-(3aalpha,6beta,7aalpha))-isomer
coronarin D: from hedychium coronarium; inhibits both constitutive and inducible nuclear factor-kappa b pathway activation, leading to potentiation of apoptosis, inhibition of invasion, and suppression of osteoclastogenesis
coronatine: consists of a coronafacic acid joined by an amide bond to coronamic acid by coronafacate ligase; phytotoxin produced by pseudomonas syringae; rn given refers to (3as-(3aalpha,4(1r*,2r*),6beta,7alpha))-isomer;
coronatine-O-methyloxime: interferes with the interaction between coronatine-insensitive protein 1 and jaz protein in plants
coronin proteins: actin-binding proteins of 49 kda with sequence similarities to g protein beta subunits
corpeptin A: a bioactive lipodepsipeptide from cultures of pseudomonas corrugata; amino acid
corpeptin B: a bioactive lipodepsipeptide from cultures of pseudomonas corrugata; amino acid
correolide: from costa rican tree, spachea correae; selectively inhibits voltage-gated potassium channel kv1.3 in human t lymphocytes by membrane depolarization
correxonuclease: hydrolyzes single-str&ed dna; initiates hydrolysis at both 3' and 5' termini of such dna, yielding 5'-phosphorylated oligonucleotides averaging 4 nucleotides; can excise pyrimidine dimers which are adjacent to the break
corrigendum compound: mf c32-h34-n2-o5-s2
corrin reductase, Brucella melitensis: catalyzes reduction of co(ii) to co(i) during cobalamin biosynthesis
corrodecin, Eikenella corrodens: might play an important role at the periodontal site
corrugoside: has immunostimulatory activity; isolated from the marine sponge axinella corrugata
cortagine: chimeric peptide, [glu(21),ala(40)][sauvagine(1-12)]x[human/rat corticotropin-releasing factor(14-30)]x[sauvagine(30-40)]