NLK-NML/MeSH-CZ-2025-notes huggingface dataset:
fim 1: fluorescein-conjugated bis(indole)maleimide inhibitor of protein kinase c; can serve as useful fluorescent probe for protein kinase c
fim 2: fluorescein-conjugated bis(indole)maleimide inhibitor of protein kinase c; can serve as useful fluorescent probe for protein kinase c
fim2 protein, Bordetella: a major fimbrial subunit; isolated from bordetella pertussis; has been sequenced
fim3 protein, Bordetella: a major fimbrial subunit; isolated from bordetella pertussis; amino acid
fimB protein, Bordetella: shows homology with chaperone-like fimbrial proteins; implicated in biosynthesis of both serotype 2 & 3 fimbriae; mw 24 kda; amino acid sequence has been determined
fimB protein, E coli: catalyzes the inversion of the 314-bp fim switch that is the basis of phase-variable expression of type 1 fimbriae ; has been sequenced
fimC protein, Bordetella: mw 92 kda; shows homology with a class of outer membrane proteins involved in export of fimbrial subunits
fimC protein, E coli: mw 92 kda; shows homology with a class of outer membrane proteins involved in export of fimbrial subunits
fimD protein, Bordetella: fimd gene necessary for surface localization of type 1 fimbriae; amino acid sequence given in first source
fimD protein, E coli: fimd gene necessary for surface localization of type 1 fimbriae; amino acid sequence given in first source
fimD protein, bacteria: fimd gene necessary for surface localization of type 1 fimbriae; amino acid sequence given in first source
fimE protein, E coli: in the expression of type 1 fimbriae, directs the phase switch to the off position; has been sequenced
fimH protein, E coli: a protein found at the tip of a bacterial pilus which adheres to the urinary bladder; fimh adhesin mediates binding to mannose oligosaccharides; the papd chaperone protein carries fimh from cytoplasm to pili membrane; amino acid sequence given in first source
fimZ protein, Bacteroides nodosus: a possible minor fimbrial protein from serogroups d & h1 of bacteroides nodosus; amino acid sequence given in first source
fimbriae Y protein, Salmonella: a coactivator of type 1 fimbriae in salmonella enterica serovar, salmonella typhi and salmonella typhimurium; has been sequenced
fimbriae-associated protein, Actinobacillus: 76 amino acids, 8 kda; nucleotide sequence given in first source; genbank d83053
fimbriatone: has antineoplastic activity; isolated from dendrobium fimbriatum
finerenone: a potent, selective, and orally available nonsteroidal mineralocorticoid receptor antagonist
fipronil sulfone: insecticide fipronil and its metabolite fipronil sulphone inhibit the rat alpha1beta2gamma2l gaba(a) receptor
fiprozyme: catalyzes release of fibrinopeptide b from fibrinogen; isolated from venom of agkistrodon contortrix contortrix
firibastat: has antihypertensive activity; a dimer of ec33 with a disulfide linkage
firsocostat: an inhibitor of acetyl-coenzyme a carboxylase in liver; for treatment of hepatic steatosis and fibrosis associated with nonalcoholic fatty liver disease
firuglipel: g protein-coupled receptor 119 agonist for treatment of type 2 diabetes
fiscalin A: isolated from culture broth produced by neosartorya fischeri; inhibits the binding of substance p ligand to human neurokinin receptor
fiscalin B: isolated from culture broth produced by neosartorya fischeri; inhibits the binding of substance p ligand to human neurokinin receptor
fiscalin C: isolated from culture broth produced by neosartorya fischeri; inhibits the binding of substance p ligand to human neurokinin receptor
fisogatinib: fibroblast growth factor receptor 4 (fgfr4) inhibitor
fissinolide: from the seeds of a godavari mangrove, xylocarpus moluccensis; exhibits marked antifeedant activity against the third-instar larvae of brontispa longissima (gestro)
fistulain A: has both antiviral and antineoplastic activities; isolated from cassia fistula
fistulaquinone A: from the twigs of cassia fistula with anti-tobacco mosaic virus (anti-tmv) activity
fistulaquinone B: from the twigs of cassia fistula with anti-tobacco mosaic virus (anti-tmv) activity
fistulaquinone C: from the twigs of cassia fistula with anti-tobacco mosaic virus (anti-tmv) activity
fistupyrone: effective against alternaria brassicicola, which infects chinese cabbage; isolated from streptomyces
fitoestril: used to treat menopausal symptoms; consists of trifolium pratense, dioscorea villosa rhizome, crataegus oxyacantha, griffonia simplicifolia, vitamin d3, vitamin e, and zinc gluconate
fitusiran: sirna that inhibits anticoagulant pathways. used in hemophilia treatment
five-valent pneumococcal conjugate vaccine: a five-valent (type 6b, 23f, 14, 18c, and 19f) pneumococcal conjugate vaccine (pcv) for children under two
fixB protein, E coli: maybe involved in a redox process involved in nitrogen fixation; part of the fixabc region; amino acid sequence given in first source
fixX protein, Azorhizobium caulinodans: from azorhizobium caulinodans; part of fixabc region; amino acid sequence given in first source
fj protein, Drosophila: a type ii membrane glycoprotein; expressed in the developing leg, wing, eye and optic lobe of drosophila; amino acid sequence given in first source; refseq nm_058135
fkh protein, Xenopus: homologous to rat liver transcription factor hnf-3alpha; distinct from xfkh1; amino acid sequence given in first source
fl(2)d protein, Drosophila: a nuclear protein with hq-rich domain required for female-specific splicing of sxl and tra pre-mrnas; amino acid ; genbank d14661
flaA protein, bacteria: flaa gene was originally named flic1; from spirochaeta & many other bacteria; flagellar filament protein; amino acid sequence given in first source
flaB flagellin: endoflagellar subunit protein from leptospira & other bacteria; flab gene was originally named flic2; amino acid sequence given in first source; prefer flab1, flab2, flab3
flaB1 protein, Methanococcus voltae: endoflagellar protein; amino acid sequence given in first source
flaB1 protein, bacteria: mw 34.5 kda; endoflagellar protein; amino acid sequence given in first source
flaB3 protein, Treponema pallidum: mw 31 kda; endoflagellar protein; amino acid sequence given in first source
flabelliferin A: from the south pacific sponge carteriospongia flabellifera
flabelliferin B: from the south pacific sponge carteriospongia flabellifera
flaccidoside IV: from the rhizomes of anemone flaccida with inhibitory activities on lps-induced no production in macrophage raw264.7 cells
flaccidoxide-13-acetate: from the southern african soft coral cladiella kashmani
flacourtoside F: inhibitor of chikungunya and dengue virus replication from flacourtia ramontchi
flacumin: flavone aglycones from bioflavonoids with hepatoprotective properties
flagella root protein, Tetraselmis striata: calcium-modulated contractile protein of striated flagellar roots; phosphoprotein with mw 20,000 isolated from striated flagellar roots; largely responsible for mobile behavior of flagella
flagellar calcium-binding protein, Trypanosoma cruzi: amino acid sequence given in first source; mw 24-kda; isolated from trypanosoma cruzi
flagellin N-methylase: n-methylates select lysine residues of flagellin; flib isolated from salmonella typhimurium; genbank z54217
flagellum protein 41-kDa, Tritrichomonas suis: an ef-hand calcium-binding protein in the flagellum of the protozoan tritrichomonas suis; genbank tsu011991-2
flagellum-specific antigen, Trypanosoma: found in various species of trypanosoma; mw 19,000
flammulin protein, Flammulina velutipes: a ribosome-inactivating protein from fruiting bodies of the winter mushroom; has been sequenced
flavalin A: neuroprotectant from the formosan soft coral lemnalia flava
flavalin B: neuroprotectant from the formosan soft coral lemnalia flava
flavanone 7-O-beta-glucosyltransferase: catalyzes the glucosylation of the 7-oh group of naringenin to prunin; from citrus paradisi; proposed ec 2.4.1.185
flavanone synthetase: forms naringenin & eriodictytol from malonyl-coa & p-coumaroyl-coa or malonyl-coa + caffeoyl-coa, respectively
flavastacin: an o-glycosylated prokaryotic zinc metalloendopeptidase; related to astacin; cleaves peptides on the amino terminal side of aspartic acid; isolated from flavobacterium meningosepticum; amino acid sequence given in first source; genbank l37784
flavimycin A: peptide deformylase inhibitory compound from aspergillus flavipes
flavimycin B: peptide deformylase inhibitory compound from aspergillus flavipes
flavobacterin protein, Flavobacterium aquatile: macromolecular protein, the active component showing lipase & phospholipase activities; from flavobacterium aquatile b5x
flavocetin A: binds platelet glycoprotein ib; isolated from trimeresurus flavoviridis; amino acid
flavocommelin: a component of the blue supramolecular pigment from commelina communis
flavocytochrome P450 BM3 monoxygenases: a fatty acid monooxygenase; catalyzes hydroxylation of medium- and long-chain fatty acids at omega-1, omega-2 and omega-3 positions, such as 14-16 carbons lauric, myristic, and palmitic acids; from bacillus megaterium; induced by phenobarbital & other barbiturates; cytochrome p-450 (bm-3) includes: cytochrome p450 102 (ec 1.14.14.1); nadph-cytochrome p450 reductase (ec 1.6.2.4)
flavocytochrome c3: 63.8 kda protein from shewanella putrefaciens with fumarate reductase activity; amino acid
flavodoxin 1: from azobacter vinelandii; n-terminal amino acid sequence given in first source
flavofungin: macrolide antifungal antibiotic; mixture of 13,15,17,19, 21,23,25,27-octahydroxy-31-isopropyl- & 13,15,17,19,21, 23,25,27-octahydroxy-31-sec-butyl-14-methylhentriaconta- 2,4,6,8,10,28-hexaene-31-olide
flavohemoglobin denitrosylase: catalyzes the reaction of heme-bound oxygen with nitric oxide to form nitrate; has been sequenced
flavohemoprotein, Bacteria: involved in the gas metabolism during denitrification; from many bacteria; amino acid ; genbank x74334
flavokawain B: from piper methysticum forst (kava kava) roots
flavokawain C: antineoplastic from roots of kava (piper methysticum forst)
flavomannin-6,6'-dimethylether: antineoplastic from common edible mushroom, tricholoma equestre
flavone 7-O-beta-glucosyltransferase: a number of flavones, flavonones and flavonols can act as acceptors; different from ec 2.4.1.91
flavone C-glycoside, apigenin 6-C-alpha-arabinofuranosyl 8-C-alpha-arabinopyranoside: from bulbophyllum retusiusculum
flavone synthase I: catalyzes the overall conversion of 2s-flavanones into the corresponding flavones in the presence of molecular oxygen, 2-oxoglutarate, ferrous ion, & ascorbate
flavone-3,4',7-trihydroxy-3'-methoxy-7-glucoside: a flavone glucoside from deverra scoparia that inhibits porcine liver carboxylesterase
flavone-8-acetic acid dimethylaminoethyl ester: as with flavone-8-acetic acid, direct cytotoxicity is minimal; cytotoxicity appears linked with cells' dependence on glycolysis as source of energy
flavonoid 1-2 rhamnosyltransferase: encoded by gene cm1,2rhat, a key enzyme in the biosynthesis of the bitter flavonoids of citrus; genbank ay048882
flavonoid 3',5'-hydroxylase: plant p-450 enzymes involves in the hydroxylation of (colorless) dihydroflavonols in the 3' and 5' positions; a particularly important step in flavonoid synthesis which is directly visible through the color of the flower as red or purple/blue anthocyanins are formed
flavonoid 6-hydroxylase: catalyzes the hydroxylation of ring a of flavonoids; from soybean
flavonoid 7-demethylartonol E: from the root bark of artocarpus
flavonoid 8-hydroxylase, Chrysanthemum segetum: an nadph and fad dependent enzyme catalyzes hydroxylation of flavonoids in position 8 from petals
flavonol 2'-O-glucosyltransferase: transfers glucose from udpg to position 2' of partially methylated flavonols
flavonol 2,4-dioxygenase: a type 2 cu(ii)-containing glycoprotein from aspergillus niger; catalyzes the conversion of quercetin to 2-protocatechuoylphloroglucinol carboxylic acid (o2 to co)
flavonol 3-O-beta-heterodisaccharidase, Fagopyrum esculentum: used for the release of rutinose from rutin
flavonol 3-O-glucosyltransferase: acts on a variety of flavonols including quercetin & quercetin 7-o-glucoside
flavonol 3-sulfotransferase: amino acid sequence given in first source; acts on quercetin; isorhamnetin; rhamnetin and kaempferol
flavonol 4'-sulfotransferase: amino acid sequence given in first source; adds a second sulfate to various flavonol 3-sulfates
flavonol 6-hydroxylase: specific for 6-hydroxylation of partially methylated flavonols
flavonol synthase: catalyzes the dehydrogenation of dihydroflavonols to flavonols
flavoredoxin: an fmn-binding protein that passes electrons from flavodoxin or ferredoxin to desulfoviridin; isolated from desulfovibrio gigas; amino acid ; genbank af225976
flavoridin protein, Trimeresurus: a disitintegrin from trimeresurus venom
flavostatin: isolated from trimeresurus flavoviridis venom; amino acid sequence given in first source
flavovilase: a thrombin-like enzyme, with kinin-releasing activity from trimeresurus flavoviridis (habu) venom; mw 26.5 kda; partial amino acid
flavoviridiobin: a thrombin-like enzyme from the venom of trimeresurus flavoviridis (habu); mw 48 kda, 237 amino acid residues; partial amino acid
flavoxobin: coagulant enzyme from trimeresurus flavoridis venom; acts on fibrinogen to produce a clot at relatively slow rate; releases only fibrinopeptide a in the conversion of fibrinogen to fibrin
flavumchalcone: from the leaves and stem bark of campylospermum flavum (ochnaceae)
flavumindole: from the leaves and stem bark of campylospermum flavum (ochnaceae)
flavumycin A: aromatic heptaenic antibiotic contains mycosamine upon acid hydrolysis
flazinamide: structurally similar to flazin; has anti-hiv activity
flbA protein, Aspergillus nidulans: flba - fluffy low brla expression; activates brla, a primary regulator of conidiophore development; shows 30% amino acid sequence identity to saccharomyces cerevisiae sst2 protein; amino acid sequence given in first source; genbank l24395; do not confuse with the bacterial protein flba
flbA protein, Campylobacter jejuni: a flagellar biosynthesis protein; may be important in flagellum biosynthesis; amino acid sequence given in first source
flbA protein, Helicobacter pylori: a flagellar biosynthesis protein; may be important in flagellum biosynthesis; amino acid sequence given in first source
flbN protein, Caulobacter crescentus: from caulobacter basal body; 30.8% identitcal with the protein encoded by the salmonella typhimurium basal body l-ring gene, flgh; amino acid sequence given in first source
fleN protein, Pseudomonas aeruginosa: regulator of flagellar gene expression; from pseudomonas aeruginosa; amino acid
fleephilone: inhibits binding of rev protein to the rev responsive element; isolated from trichoderma harzianum
flemingin G: cytotoxic and antioxidant constituent of the leaves of flemingia grahamiana
flemingin H: cytotoxic and antioxidant constituent of the leaves of flemingia grahamiana
flemingipanic acid: isolated from the leaves of clerodendrum formicarum, a lameacious plant of cameroon
flemiphilippinin D: from flemingia filippinensis; ; rn given refers to (s)-isomer; rn for cpd without isomeric designation not avail 10/91
fletazepam: centrally acting muscle relaxant more effective than diazepam in preventing convulsions & muscle rigidity
flexibilisin A: from the cultured and wild-type soft corals sinularia flexibilis
flexibilisin B: from the cultured and wild-type soft corals sinularia flexibilis
flexibilisolide A: from the cultured and wild-type soft corals sinularia flexibilis
flexibilisolide B: from the cultured and wild-type soft corals sinularia flexibilis
flexirubins: pigments found in the outer membrane of flexibacter elegans, characterized by non-isoprenoid omega-substituted polyene carboxylic acids esterified with 2,5-dialkylated resorcinols
flgFG protein, bacteria: two campylobacter jejuni genes flgf and flgg, fuction as a single operon (flgfg); amino acid
flgI protein, Bacteria: may assemble around the rod to form the l-ring and probably protects the motor/basal body from shearing forces during rotation; amino acid sequence given in first source
flhC protein, E coli: a transcriptional activator of the escherichia coli flagellar class ii operons
flhD protein, E coli: a transcriptional activator of the escherichia coli flagellar class ii operons; amino acid sequence has been determined
flhF protein, Bacteria: from bacillus subtilis; flagellar gene that encodes a gtp-binding protein with similarities to members of the srp54 family of proteins; mw 41 kda; amino acid sequence given in first source
fliE protein, E coli: flagellar hook-basal body complex protein; located within the hook-basal complex; may act as an adaptor protein between the ring and rod substructures of the flagellum; amino acid sequence given in first source; rn given refers to flie, e. coli
fliH protein, Bacteria: flagellar assembly protein; needed for flagellar regrowth and assembly; amino acid sequence given in first source
fliI protein, Drosophila: c-terminal portion homologous to gelsolin; 58% identical to human fli protein; has been sequenced; refseq nm_080358
fliI protein, bacteria: flagellar protein a wide variety of bacterial species; has h(+)-transporting two-sector atpase (ec 3.6.3.14) activity; amino acid sequence given in first source; do not confuse with flightless i protein
fliJ protein, Bacteria: flagellar protein; required for formation of basal bodies; has 23% homology to bacillus subtilis protein chef; amino acid sequence given in first source
fliT protein, Bacteria: a flagellar protein; amino acid sequence given in first source; may act a s substrate specific export chaperone, facilitating the incorporation of
fliY protein, E coli: a commercially available crude protein extract used in measuring cystine levels in cystinosis; amino acid sequence has been determined
fliZ protein, Bacillus subtilis: flagellar biosynthetic protein from bacillus subtilis; 219 amino residue protein; mw 24.8 kda; amino acid sequence given in first source
flibanserin: a 5-ht(2a) receptor antagonist and 5-ht(1a) receptor agonist in rat cerebral cortex
flight muscle protein, Act88F: amino acid sequence given in first source; from drosophila simulans
flinderole A: antimalarial bis-indole alkaloid from flindersia species
flinderole B: antimalarial bis-indole alkaloid from flindersia species
flinderole C: antimalarial bis-indole alkaloid from flindersia species
flocculant protein MO 2.1, Moringa oleifera: from seeds of moringa oleifera; mw 6.5 kda; amino acid sequence given in first source
floctafenine: was heading 1979-94 (see under anthranilic acids 1979-80); use anthranilic acids to search floctafenine 1979-94; anti-inflammatory analgesic similar in action to aspirin; it inhibits prostaglandin synthesis
flophemesyl: protecting group for steroid alcohols for volatilization & detection in gas chromatography
flopristin, linopristin drug combination: a mixture of flopristin (rpr132552a) and linopristin (rpr202698)
flor-essence: an herbal tea made from burdock root, turkish rhubarb root, sheep sorrel, inner bark of slippery elm, watercress, blessed thistle, red clover, and kelp; used as a supplement to radiation and chemotherapy for treating cancer
floral-binding protein 11, Petunia: a mads box protein that determines ovule identity in petunia; 90% identity with fbp7
floratheasaponin A: acylated oleanane-type triterpene oligoglycoside with anti-hyperlipidemic activity from flowers of the tea plant (camellia sinensis)
floratheasaponin B: acylated oleanane-type triterpene oligoglycoside with anti-hyperlipidemic activity from flowers of the tea plant (camellia sinensis)
floratheasaponin C: acylated oleanane-type triterpene oligoglycoside with anti-hyperlipidemic activity from flowers of the tea plant (camellia sinensis)
florfenicol resistance protein, Pasteurella piscicida: gene pp-flo is derived from a transferable r-plasmid of pasteurella piscicida; amino acid sequence given in first source; genbank d37826
floribundasaponin D: a spirost-5-en-3-ol steroid glycoside from indian medical plants; used in liposomal drug delivery; rn given from chem abst index guide 1982-86
florilenalin-2alpha-O-isobutyrate: from centipeda minima
florxenilide A: xenicane-type diterpene with cytotoxicity from xenia florida
florxenilide B: xenicane-type diterpene with cytotoxicity from xenia florida
florxenilide C: xenicane-type diterpene with cytotoxicity from xenia florida
flosin B: from dried leaves of lagerstroemia speciosa (lythraceae)
flotillins: components of cell membrane lipid rafts; don't confuse esa flotillin, human with esa antigen, human, a synonym of epcam
flp1 protein, Trichomonas vaginalis: fibronectin-like iron-regulated protein; amino acid
flp2 protein, Trichomonas vaginalis: fibronectin-like iron-regulated protein; amino acid
flt3 ligand protein: amino acid sequence given in first source; a ligand for the flt3/flk-2 tyrosine kinase receptor; a type 1 transmembrane protein that stimulates proliferation of hematopoietic cells; has potential for natural killer cell-based anti-cancer and antiviral therapy; genbank af282985-6 (bovine)
fluanisone: former provisional as haloanisone; structure; rn given refers to parent cpd
fluazuron: a benzoyl phenylurea compound; acatak (tradename) is a pour-on tick development inhibitor containing fluazuron as its active ingredient
flubromazolam: a benzodiazepine and potent sedative that is used as a designer drug
fluciclovine F-18: a radioactive diagnostic agent used for the detection of recurrent prostate cancer by positron emission tomography
flucindole: rn given refers to parent cpd with unspecified isomeric designation
flucloronide: synthetic glucocorticoid with anti-inflammatory properties; minor descriptor (75-83); on-line & index medicus search pregnadienetrols (75-83); rn given refers to (6alpha,11beta,16alpha)-isomer
flucycloxuron: benzoylphenylurea insecticide; a chitin synthesis inhibitor effective on reproductive events and thickness of chorion in mealworms
flueggenine A: c,c-linked dimeric indolizidine alkaloid from flueggea virosa
flueggenine B: c,c-linked dimeric indolizidine alkaloid from flueggea virosa
fluevirosine B: from flueggea virosa; showed inhibition against the splicing of xbp1 mrna
fluevirosine C: from flueggea virosa; showed inhibition against the splicing of xbp1 mrna
flumedroxone: used for treatment of migraine & premenstrual tension; rn given refers to parent cpd
flumedroxone acetate, meprobamate, n-pentylhydroflumethiazide drug combination: used in treatment of premenstrual tension; contains 1 mg flumedroxone acetate, 2 mg n-pentylhydroflumethiazide, 200 mg meprobamate
flunitrazepam receptor: binds to the alpha 1 subunit of the gaba/benzodiazepine receptor
flunitrazolam: designer benzodiazepine discovered in 1960's but never marketed
fluoracizine: russian drug; 2-trifluoromethyl analog of chloracizine; rn given refers to parent cpd
fluorapatite: rn refers to fluorapatite [ca5f(po4)3])
fluorenhymustine: anticancer nitrogen mustard where n,n'-bis(2-chloro-ethyl)amino group, the established anticancer functionality, is attached to the 2-ethyl fluorenone hydantoin moiety
fluorenylmethoxycarbonyl-2-mercaptobenzothiazole: reagent used to introduce the fmoc group without side reactions
fluorenylmethyloxycarbonyl-4-(dimethylphosphono)-2-aminobutanoic acid: used for production of 2-amino-4-phosphonobutanoic acid-containing peptides
fluorescein hydrazide: formed by the reaction of adipic acid dihydrazide and fluorescein isothiocyanate
fluorescein hydrizido 2-imidophenol: structure in first sopurce
fluorescein hydrizido 2-imidophenylboronic ester: structure in first sopurce
fluorescein isothiocyanate-peanut agglutinin: a stain used in determining sperm acrosome reaction
fluorescein isothiocyante avidin: binds to a-cells of sectioned pancreas
fluorescein mono-p-guanidinobenzoate: rn given refers to hcl; rn for parent cpd not available 3/88
fluorescein thiocarbamoyl casein: casein reacted with fluorescein isothiocyanate to form fluorescein thiocarbamoyl derivative
fluorescein thiocarbamylethylenediamine: used as label in fluoroimmunoassay for conjugated chenodeoxycholic acid
fluorescein-11-deoxyuridine triphosphate: rn given is for tetralithium salt
fluorescein-12-dideoxyuridine triphosphate: used for quantifying dna strand breaks during apoptosis
fluorescein-PEG2-TMQ-Luc: a luminogenic transport uptake probe
fluorescein-Trp(25)-exendin-4: a biologically active fluorescent probe for the human glp-1 receptor
fluorescein-ovalbumin: application to conjunctival sac causes sensitization for conjunctival type 1 hypersensitivity reactions & mast cell degranulation
fluorescein-thyrotropin-releasing hormone: fluorescent trh analog made by coupling pglu-his-pronh(ch2)6nh2 to fluorescein isothiocyanate
fluoresceinthiocarbamoyl-Lys-GlcNAc-1-4-MurNAc-Ala-isoglutamine: ; muramyl peptide derivative labeled with fitc
fluoresceinyl-arginyl-glutamyl-aspartyl-glutamyl-aspartyl-glutamyl-isoleucyl-glutamyl-tryptophan: binds and stabilizes the tumor suppressor p53 core domain, thereby preventing denaturation; may serve as an antineoplastic agent
fluorescent Tat protein (49-57): tat protein (49-57) labeled with a fluorescein and a tetramethylrhodamine
fluorescent age pigment: age-associated alteration found in the cytoplasm of the postmitotic cells of eukaryotes; represents end-product of lipid peroxidation reactions
fluorescent dye D 282: rn given refers to hcl; rn for parent cpd not available
fluorescent protein 583: a fluorescent protein from discosoma coral and its mutants possesses a unique far-red fluorescence; dtomato is a dimeric variant of dsred; amino acid
fluorescent whitening agent VBL: commercially-available fluorescent whitening agent used in the paper-making industry
fluorinase: catalyses the conversion of fluoride ion and s-adenosylmethionine to 5'-fluoro-5'-deoxyfluoroadenosine
fluoro-1,3-dimethyloadamantane: a lecithin-emulsified perfluorochemical
fluoroacetate-specific dehalogenase: acts on fluoroacetamide at 0.1 the rate for fluoroacetate
fluoroazomycin-2'-deoxyribofuranoside: a pet radiotracer for imaging tumor hypoxia
fluorobutyl(2,5-dimethyl-7-(2,4,6-trimethylphenyl)-7H-pyrrolo(2,3-d)pyrimidin-4-yl)ethylamine: a pet/spect ligand for the crf1 receptor
fluorocarazolol: ; rn refers to (18f)labelled (s-(r*,s*)-stereoisomer
fluorocarbon 72: a perfluorinated alkyltetrahydrofuran cpd; contains 1% w/v osmium tetroxide
fluorocitrate: competitve inhibitor of aconitase; effects morphology of kidney tubules in fluorocitrate poisoning; rn given refers to cpd with unspecified isomeric designation
fluoroclebopride: ; a dopamine d1 and d2 receptor-based imaging agent
fluorodibromomethane: hcf(x1a') radicals were produced by laser photolysis of fluorodibromomethane
fluoroethyl-desmethyl-ABP688: a pet radioligand for mglur5 receptors
fluorohydroxyapatite: biocoating for orthopaedic prostheses
fluoroindolocarbazole A: indolocarbazole from saccharothrix aerocolonigenes atcc 39243
fluoroindolocarbazole B: indolocarbazole from saccharothrix aerocolonigenes atcc 39243
fluoroindolocarbazole C: indolocarbazole from saccharothrix aerocolonigenes atcc 39243
fluoromethyl 2,2-difluoro-1-(trifluoromethyl)vinyl ether: structure cf2=c(cf3)och2f; a vinyl ether
fluoropalonosetron: a pet radiotracer for imaging 5-ht3 receptors
fluorophen: structure & rn given in first source; rn given refers to (2alpha,6alpha,11r*)-(+-)-isomer
fluorophlogopite: analog of mica in which the potassium ions on the basal surface have been replaced by aluminum ions
fluorophosphate: inhibits phosphorylas phosphatase irreversibly; rn given refers to parent cpd
fluoroquinolone ethyl 6-fluoro-8-nitro-4-oxo-1,4-dihydroquinoline-3-carboxylate: has antineoplastic and anti-infective properties
fluoroxanomeline: a radiolabeled muscarinic m1-selective agonist
fluostatin I: from the south china sea-derived micromonospora rosaria scsio n160
fluostatin J: from the south china sea-derived micromonospora rosaria scsio n160
fluostatin K: from the south china sea-derived micromonospora rosaria scsio n160
fluotracen: structure; rn given refers to (cis(+-))-isomer
flupentixol, melitracen drug combination: contains melitracen & flupenthixol
fluprednidene acetate: has anti-inflammatory & anti-allergic properties; minor descriptor (75-83); on-line & index medicus search pregnadienetriols (75-83); rn given refers to (11beta)-isomer
fluprostenol: synthetic prostaglandin f 2 alpha analog used as an abortifacient; rn given refers to ((1alpha(z),2beta(1e,3r*),3alpha,5alpha)-(+-))-isomer
flurbiprofen 2-amino-3-methylpyridine amide: inhibits both cyclooxygenase and fatty acid amide hydrolase; has analgesic activity
flurbiprofen N-(3-(3-(1-piperidinylmethyl)phenoxy)propyl)-2-(2-hydroxyethylthio)acetamide: this ester moiety of flurbiprofen, an histamine h2 receptor blockader, causes less gastric damage than the methyl ester of flurbiprofen or flurbiprofen itself
fluromidine: causes hemorrhage & lowers plasma prothrombin level; rn given refers to parent cpd
fluroxene: was heading 1973-94; use ethers to search fluroxene 1973-94
fluroxypyr methylheptyl ester: xrm-5084 is made up of 34.9% fluroxypyr methylheptyl ester and 65.1% proprietary emulsifier; used for the control of broadleaf vegetation
flushing solution PBSuc 50: isotonic flushing solution to protect kidneys from in situ ischemia; contains na2hpo4, nah2po4, sucrose, atp & mgcl2
flusinolid: an inhaled steroid; for the treatment of chronic obstructive bronchitis; no further information available 10/95
flustramine A: from flustra foliacea l.; exhibits muscle relaxant activity both in vivo & in vitro
flustramine B: from flustra foliacea l.; exhibits muscle relaxant activity both in vivo & in vitro
flutamide hydroxylase: catalyzes the 2-hydroxylation of flutamide
fluticasone furoate-vilanterol trifenatate: for asthma therapy
fluticasone propionate-17-carboxylic acid: metabolite of fluticasone propionate
fluticasone-formoterol: a mixture of fluticasone propionate and formoterol fumarate
flutimide: isolated from delitschia confertaspora; selectively inhibits the transcriptase of influenza viruses; structure given
fluvalinate: rn given refers to 2-cyano isomer (dl)-isomer
fluvastatin, valsartan drug combination: combination of fluvastatin and valsartan at low doses used to treat arterial wall dysfunction
fluxapyroxad: carboxamide; succinate dehydrogenase inhibitor
flvcr1 protein, zebrafish: refseq nm_001025522.1
fmdD protein, Methylophilus methylotrophus: a high affinity, binding-protein-dependent, active-transport system for short chain amides and urea from methylophilus methylotrophus; amino acid ; genbank y14964
fmdE protein, Methylophilus methylotrophus: isolated from methylophilus methylotrophus; amino acid ; genbank y14964
fmdF protein, Methylophilus: amino acid ; genbank y14964; do not confuse with polyferredoxin (fmdf)
fng protein, Drosophila: a boundary-specific signaling molecule that mediates interactions between dorsal and ventral cells during drosophila wing development; affects activity of notch receptor; has been sequenced
fo shou san: an ancient herbal decoction prepared from rhizoma chuanxiong and radix angelicae sinensis that stimulates the production of hemoglobin and erythropoietin in cultured cells
focal adhesion protein, 52-kDa: 448 amino acids; isolated from most chicken tissues; amino acid sequence given in first source; genbank z50798
fodaxin: neuron-specific protein that is confined to the axonal plasma membrane; the first protein to be described that discriminates between the unique regions of beta spectrin isoforms; amino acid sequence has been determined
fodrin: comprised of two polypeptides (mol wt 250,000 & 240,000) axonally transported
foegraecumoside A: cytotoxic; from lysimachia foenum-graecum
foeniculoside X: phenolic glycoside from foeniculum vulgare fruit with antioxidant activity
foeniculoside XI: phenolic glycoside from foeniculum vulgare fruit with antioxidant activity
foenumoside B: an anti-adipogenic agent isolated from lysimachia foenum-graecum
foetidin: extract of momordica foetida consisting of equal parts sitosterol glucoside & 5,25-stigmastadiene-ol glucoside
foetidissimoside B: isolated from the roots of cucurbita foetidissima
foetinoside: isolated from the rhizomes of cimicifuga foetida l.
foi protein, Drosophila: may be a regulator of e-cadherin expression or function; has been sequenced; refseq nm_079250
foitite: an adsorbent for removal of lead(ii) and copper(ii) from aqueous solution
fokalmin: drug combination of above compounds; used as a paste with iodoform in treatment of gingival diseases
folX protein, E coli: forms l-threo-dihydroneopterin triphosphate; folx is a subunit of the folx tetramer complex that makes up dihydroneopterin triphosphate 2'-epimerase
folate transporter 1, Leishmania infantum: involved in methotrexate resistance; genbank ay577522
folate-glutathione-polyethyleneglycol-distearoyl phosphatidylethanolamine: a folate receptor ligand
folenolide: from antioxidant from hypericum oblongifolium (guttiferae)
folianin B: annonaceous acetogenin isolated from seeds of annona cornifolia a. st. hil (annonaceae)
folic acid deaminase, Dictyostelium discoideum: chemotaxis regulating enzyme from dictyostelium discoideum; splits folic acid into 6-hydroxymethylpterin & p-aminobenzoylglutamic acid;
folic acid oxidase: enzyme from human red blood cell membranes; catalyzes oxidation of folic acid to pterin-6-aldehyde plus p-aminobenzoylglutamic acid in presence of h2o2; singlet oxygen is involved
folic acid-5-aminofluorescein-glutamic-paclitaxel: multi-small molecule conjugation as targeted delivery carrier for tumor therapy
folic acid-fluorescein-5(6)-isothiocyanate-arginine-paclitaxel: small molecule conjugation as targeted delivery carrier for tumor therapy
folic acid-poly(ethyleneglycol)-2-distearoylglycero-3-phosphoethanolamine: a drug carrier
folic aid-6-(4,7-bis(2,3-dihydrothieno(3,4-b)(1,4)dioxin-5-yl)-2H-benzo(d)(1,2, 3)triazol-2-yl)hexan-1-amine: a fluorescent bioconjugate with antineoplastic activity
folicitin: antioxidant from hypericum oblongifolium (guttiferae)
folin: water-soluble extract from sasa albomarginata makino & et shibata containing polysaccharides
folipastatin: from aspergillus unguis; inhibitor of phospholipase a2; has depsidone carbon skeleton
follicle stimulating hormone, beta subunit (1-15): induces uptake of calcium by liposomes
follicle stimulating hormone, beta subunit (33-53)-(81-95)-peptide amide, human: a synthetic peptide encompassing the discontinuous segments of the human fsh beta subunit, amino acids (33-53) and (81-95); has higher affinity for fsh receptor than either synthetic hfsh-beta-(33-53) or hfsh-beta-(81-95)
follicle stimulating hormone, beta subunit (51-65): a synthetic peptide encompassing the sequence of human fsh beta subunit, amino acids (51-65); induces uptake of calcium by liposomes
follicle stimulating hormone, beta subunit (81-95), human: a synthetic peptide encompassing the sequence of human fsh beta subunit, amino acids (81-95); amino acid sequence given in first source
follicle stimulating hormone, human, with HCG C-terminal peptide: a long-acting recombinant fsh like substance, consisting of the human fsh alpha-subunit and a hybrid beta-subunit that is composed of the human fsh beta-subunit and the c-terminus part (ctp) of the human hcg beta-subunit
follicle-stimulating hormone, beta subunit precursor, porcine: nucleotide sequence given in first source
follicle-stimulating hormone-suppressing protein, rat: contains ser, gly, arg, thr, ala, pro, val, lys, hexoses, & ethanolamine
follipsin: from fluid of porcine ovarian follicles during maturation; distinct from kallikrein & factor xia; consists of two different peptide chains of mw 45 & 32 kda; partial amino acid sequence given in first source
follistatin, 288-amino acid isoform: binds to activin and neutralizes its biologic activities & enlarges intact liver of adult rats
follitropin alfa: a pharmaceutical preparation of recombinant human fsh alpha and beta subunits
follitropin beta: a pharmaceutical preparation of human recombinant fsh alpha and beta subunits. do not confuse with follicle stimulating hormone, beta subunit
folylpoly-alpha-glutamate synthetase: synthesizes alpha-carboxyl-linked folylpolyglutamates
folylpolyglutamate synthetase: catalyze the formation of amide bond between gamma-carboxyl of a folate and amino group of glutamic acid folate; any folic acid including polyglutamates; refseq nm_120680 (fpgs1, arabidopsis)
fomA protein, Fusobacterium: from f. nucleatum strain fev1; 348 aa residues, mw 40 kda; genbank x66735
fomajorin S: structural element essential for its toxicity is the 2h- or 2-methylindan-2-acid moiety
fominoben: was mh 1975-92 (see under morpholines 1975-90); use morpholines to search fominoben 1975-92
fomivirsen: an antisense compound; used to treat cmv retinitis in patients with aids; rn refers to eicosasodium salt
fomocain: a basic ether with local anesthetic action & relative low toxicity & systemic effects; minor descriptor (77-86); on-line & index medicus search phenyl ethers (77-86); rn given refers to parent cpd
fon protein, Drosophila: a hemolymph protein involved in clotting and puparium formation; refseq nm_165287
fonazine: has considerable antiemetic & serotonin antagonistic action used mainly in allergic skin conditions; minor descriptor (75-84); on-line & index medicus search phenothiazines (75-84); rn given refers to parent cpd
foncitril 4000: each 16g granulate contains 1.3g citric acid, 2g mono-k citrate, 2g mono-na citrate & 100mg trimethoxybenzene
fontolizumab: a humanized anti-interferon gamma monoclonal antibody in phase ii clinical trials for treatment of autoimmune disease
for protein, Drosophila: required for visual pattern memory; has been sequenced; refseq nm_058139
forasartan: ; an angiotensin at(1) receptor antagonist; angiotensin ii receptor antagonist; used in treatment of congestive heart failure
fordine: isolated from chinese herbs huperziaceae, including phlegmariurus fordii (baker) ching and huperzia serrata (thunb.) trev.
forkienin A: cytotoxic, from the twigs and leaves of fokienia hodginsii
forkienin B: cytotoxic, from the twigs and leaves of fokienia hodginsii
form3 protein, Drosophila: involved in f-actin assembly; refseq nm_001014571
formadicin: produced by flexiabacter alginoliquefaciens sp. nov. yk-49
formadienoate-A: from clerodendrum formicarum (lamiaceae) of cameroon
formadienoate-B: from clerodendrum formicarum (lamiaceae) of cameroon
formaecin 1 protein, Myrmecia gulosa: isolated from the ant myrmecia gulosa; amino acid
formaldehyde dehydrogenase (glutathione): see ec 1.2.1.46 for formaldehyde dehydrogenase
formaldehyde dehydrogenase (pyridine nucleotide independent): dichlorophenol-indophenol or potassium ferricyanide act as electron acceptors
formaldehyde dehydrogenase, glutathione-independent: a zinc-containing metalloenzyme that catalyzes the nad+-dependent oxidation of long-chain alcohols; genbank d21201
formaldehyde dismutase: contains noncovalently bound nad(h); forms equimolar amounts of corresponding alcohols & acids from various aldehydes
formaldehyde ferredoxin oxidoreductase: contains molybdopterin as the organic component of tungsten cofactor
formaldehyde reductase: putative enzyme that catalyzes reduction of formaldehyde to methanol using nadh
formaldehyde transketolase: from yeast; formaldehyde plus xylulose-5-phosphate yields glyceraldehydephosphate & dihydroxyacetone
formaldehyde, meta-cresolsulfonic acid drug combination: anti-infective agent (vaginal); condensation product of meta-cresolsulfonic acid and formaldehyde
formaldehydeaminal: condensation product of formaldehyde & 2 moles of a secondary amine
formaldehydesulfoxylate: antidote for mercury poisoning; rn given refers to parent cpd
formalinized extracellular antigen: isolated from melanoma cells; used to immunize mice against challenge with melanoma cells
formamicin: from culture broth of actinomycete, saccharotheix sp.
formamidase: mediates the highly specific hydrolysis of formamide to produce formate and ammonium
formamidoeudesm-11-ene: eudesmane-type compound from the caribbean sponge axinyssa ambrosia
formate dehydrogenase (NADP+): catalyzes the formation of co2 & nadph from formate & nadp+
formate dehydrogenase-O: from e coli; contains selenocysteine trna-dependent fdh activity; synthesized both aerobically & anaerobically in the presence of nitrate; three subunits of this enzyme are encoded by genes fdog, fdoh & fdol
formate hydrogenlyase: consists of ec 1.2.1.2, formate dehydrogenase, plus ec 1.12.1.2, hydrogen dehydrogenase
formatrix: contains 1.25mg premarin, 10mg methyltestosterone, 400mg ascorbic acid; used in treatment of low back pain & healing of fractures in osteoporosis
formetanate: minor descriptor (72-85); on-line & index medicus search carbamates (72-85); rn given refers to parent cpd
formic acid 4-(3-oxobutyl)phenyl ester: an improved male attractant for field captures of wild melon fly (diptera: tephritidae)
formiminotetrahydrofolate cyclodeaminase: formiminotransferase catalyzes reaction of formiminoglutamate + tetrahydrofolate giving formiminotetrahydrofolate + glutamate; copurifies with the cyclodeaminase
formoic acid A: isolated from the leaves of clerodendrum formicarum, a lameacious plant of cameroon
formoic acid B: isolated from the leaves of clerodendrum formicarum, a lameacious plant of cameroon
formononetin: intermediate to formation of rotenone; has a deleterious effect on sheep grazing in "estrogenic clover" pastures; rn given refers to unlabeled cpd
formosadimer A: from the bark of calocedrus macrolepis var. formosana
formosadimer B: from the bark of calocedrus macrolepis var. formosana
formosadimer C: from the bark of calocedrus macrolepis var. formosana
formose sugars: complex mixture of sugars which arises from self-condensation of formaldehyde
formoside: from the caribbean sponge erylus formosus (choristida/astrophorida)
formoside B: from the caribbean sponge erylus formosus (choristida/astrophorida)
formosusin A: inhibits dna polymerase beta; isolated from paecilomyces formosus
formothion: was mh 1976-91 (see under insecticides, organothiophosphate 1976-90)
formoxanthone A: antibacterial and cytotoxic xanthone from the roots of cratoxylum formosum
formoxanthone B: antibacterial and cytotoxic xanthone from the roots of cratoxylum formosum
formoxanthone C: antibacterial and cytotoxic xanthone from the roots of cratoxylum formosum
formycin cyclic 3',5'-monophosphate: formycin cyclic amp analog
formycin triphosphate-terbium complex: a terbium-associated nucleotide whcih binds to catalytic site of the h+-atpase
formyl sterol oxidase: converts sterol 4-aldehyde to a carboxylic acid in presence of nadh or nadph
formyl-aminohexyl-leucyl-phenylalanyl-aminohexyl-tyrosyl-phenylalanine: triggers chemotaxis & degranulation
formyl-coenzyme A transferase: transfers a coenzyme a moiety to activate oxalic acid
formyl-cyclo(cysteinyl-leucyl-phenylalanyl-cysteinyl) methyl ester: a cyclotetrapeptide; a conformationally constrained analog of for-met-leu-phe-ome; inactive towards human neutrophils
formyl-leurosine: rn given refers to (3'alpha,4'alpha)-isomer
formyl-methenyl-methylenetetrahydrofolate synthetase: trifunctional enzyme which contains ec 6.3.4.3, formyltetrahydrofolate synthetase, plus ec 3.5.4.9, methenyltetrahydrofolate cyclohydrolase, and ec 1.5.1.5, methylenetetrahydrofolate dehydrogenase as a complex in sheep liver
formyl-methylhomoseryl-leucyl-phenylalanine methyl ester: an oxygen analog of fmlp-ome; amino acid sequence given in first source
formyl-norleucyl-leucyl-phenylalanyl-norleucyl-tyrosyl-lysine-DTPA: a chemotactic peptide analog
formylanserinone B: isolated and identified from a deep water (-4380 ft), marine-derived saltwater fungal culture
formylanthranilic acid: phytoanticipin in the plant species i. indigotica
formyldienolone: structure; rn given refers to (11alpha,17beta)-isomer
formylglutamate amidohydrolase: from pseudomonas putida; degrades formylglutamate to glutamate & formate
formylmethanofuran dehydrogenase: catalyzes the oxidation of formylmethanofuran to co2 & methanofuran with methyl viologen as artificial electron acceptor; from methanogenic bacteria
formylmethanofuran dehydrogenase, tungsten, Methanobacterium thermoautotrophicus: the enzyme consists of four subunits, each encoded by one of the four genes in the fwdabcd operon; tungsten-containing isoenzyme of ec 1.2.99.5; has been sequenced
formylmethanofuran-tetrahydromethanopterin formyltransferase: from methanobacterium thermoautotrophicum; role in methanogenesis from co2
formylmethionyl-alanyl-leucine: formed by e coli ribosomal protein l10 gene
formylmethionyl-leucyl-phenylalanyl-phenylalanyl-lysine seminaphthofluorescein: a pentapeptide fluoresceinated ligand; used to detect and quantify formyl peptide receptors
formylpyrrothine: antibiotic from the fermentation broth of saccharothrix algeriensis
formyltetrahydrofolate deformylase protein, rat: from rat liver homogenates; catalyzes the conversion of 10-formyltetrahydrofolate to tetrahydrofolate & formate; amino acid sequence has been determined; has significant homology to the purn protein of e coli & to enzymes with glycinamide ribonucleotide transformylase activity
formyltetrahydrofolate dehydrogenase: refseq nm_144776 (human), nm_022547 (rat)
fornicin A: prenylated phenolic compound with moderate cytotoxic activity from the fruiting bodies of ganoderma fornicatum
fornicin B: prenylated phenolic compound with moderate cytotoxic activity from the fruiting bodies of ganoderma fornicatum
fornicin C: prenylated phenolic compound with moderate cytotoxic activity from the fruiting bodies of ganoderma fornicatum
foroxymithine: isolated from streptomyces nitrosporeus; ; mw 575.57; mf c22-h37-n7-o11
forskoditerpenoside A: diterpene glycoside from coleus forskohlii
forskoditerpenoside B: diterpene glycoside from coleus forskohlii
forskoditerpenoside C: diterpene glycoside from coleus forskohlii
forskoditerpenoside D: diterpene glycoside from coleus forskohlii
forskoditerpenoside E: diterpene glycoside from coleus forskohlii
forsskamide: isolated from aerial parts of forsskaolea tenacissima; has cyotoxic activity against human colorectal cancer cell line
forsythiaside: rn given refers to (e)-isomer; ; from the unripe fruit of forsythia suspensa (qinglianquiao)
forsythoneoside B: neuroprotective; from the fruits of forsythia suspensa
forsythoneoside D: neuroprotective; from the fruits of forsythia suspensa
fortimicin A: rn given refers to parent cpd; abbott-44747 is for disulfate; see also records for fortimicin b & fortimicins; structure in 8th source
fortimicin KL1 methyltransferase, Micromonospora olivasterospora: isolated from micromonospora olivasterospora; methylates fortimicin kl1 to form fortimicin kk1; genbank d49442
fortimicins: includes fortimicins c,d, & ke; rn given refers to cpd with unknown mf; see also records for fortimicin a & fortimicin b
fortuitin: linear acylnonapeptide methyl ester from mycobacterium fortuitum
fos-related antigen 1: the mammalian gene fra-1 is closely related to protooncogene c-fos, and encodes a component of transcription factor ap-1; refseq nm_005438 (human); nm_010235 (mouse); nm_012953 (rat); do not confuse with fibrinogen-related antigen (fra antigen)
fosamine: bud break inhibitor for control &/or growth suppression of many woody species; rn given refers to parent cpd
fosbretabulin: a microtubule destabilizing agent isolated from combretum caffrum
fosdagrocorat: a prodrug of glucocorticoid receptor agonist dagrocorat
fosfolip: contains pantethine & phosphorylcholine chloride; has lipotropic activity
fosravuconazole L-lysine ethanolate: oral triazole antifungal agent
fostamatinib: a spleen tyrosine kinase (syk) inhibitor, metabolized to r406
fostriecin: compound contains a conjugated triene and an unsaturated lactone; from streptomyces pulveraceus
fox-4 protein, E coli: an ampc-type plasmid-mediated beta-lactamase from an escherichia coli strain isolated in spain; genbank aj277535
foxa2 protein, zebrafish: member of the fork head/hnf3 family; from zebrafish; involved in specification of axial mesoderm and the ventral cns; amino acid sequence given in first source
foxd1 protein, Xenopus: foxd1 mediates the coordinated expression of hepatocyte-specific genes
foxd3 protein, zebrafish: fkd - fork head domain; fkh - fork head; member of winged helix family
foxd4l1.1 protein, Xenopus: fork head domain protein from xenopus laevis; xfd = xenopus forkhead domain; genbank aj242676
foxh1 protein, zebrafish: a transcriptional activator and component of the tgf-beta/activin response element