NLK-NML/MeSH-CZ-2025-notes huggingface dataset:
maximiscin: antineoplastic from the fungal isolate tolypocladium sp. salcha mea-2
mayamycin: cytotoxic; from a streptomyces strain isolated from the marine sponge halichondria panicea
mayolene: mayolenes are labile defensive lipids from the glandular hairs of a caterpillar (pieris rapae)
mayoside D: oxaanthrone c-glycoside from the roots and leaves of picramnia latifolia
mayoside E: oxaanthrone c-glycoside from the roots and leaves of picramnia latifolia
mazapertine succinate: an arylpiperazine derivative; a dopamine d2 receptor antagonist
mbc protein, Drosophila: required for myoblast fusion, dorsal closure, and cytoskeletal organization; isolated from drosophila; amino acid ; similar to dock180 protein; refseq nm_057796
mbhA protein, Myxococcus xanthus: from myxococcus xanthus; has been sequenced
mbl protein, Bacillus subtilis: required for different aspects of cell morphogenesis; amino acid
mbl protein, Drosophila: required for photoreceptor differentiation in drosophila; has four isoforms a-d; genbank af011625 (d), af001626 (b), af001536 (c), af001422 (d); refseq nm_176212
mbo protein, Drosophila: 88-kda component of a nuclear pore complex
mbt protein, Drosophila: encodes a protein related to p21-activated kinase (pak); may be part of a general mechanism regulating cell number in a variety of neuronal tissues; has been sequenced; refseq nm_078651
mce2 protein, Mycobacterium tuberculosis: isolated from mycobacterium tuberculosis; amino acid
mcl1a protein, zebrafish: refseq: np_571674.1. nm_131599.1
mcm5 protein, S pombe: member of the cdc46/mcm2 family; amino acid  for nda4+; homologous to cdc46 (s cerevisiae)
mcm5 protein, Xenopus: involved in early step of dna replication & possibly initiation of dna synthesis
mcp-1 protein, C elegans: catalyzes the phosphorolysis of gdp-d-glucose to yield gdp and glucose-1-phosphate; refseq nm_001028468
mcr-2 protein, E coli: plasmid-encoded putative integral membrane protein and sulfatase; involved in colistin resistance; genbank sbv31106
mcrA protein, Streptomyces lavendulae: mitomycin radical oxidase; confers resistance to mitomycin c; oxidizes reduced form of mitomycins; isolated from streptomyces lavendulae; amino acid ; do not confuse with mcra endonuclease; genbank l29247
mcrB protein, E coli: s and l forms are 33- and 51-kda, respectively; mcr(l) may be the dna-binding restriction subunit; modified cytosine restriction system of e coli; 3 different recognition sites; m5c, m4c, & hmc; do not confuse with mcrb protein (from streptomyces); see also mcrbc endonuclease
mcrB protein, Streptomyces lavendulae: the mcr locus contains 2 genes (mcra and mcrb) that together confer resistance to mitomycin c; mcrb is a putative transcriptional activator; amino acid ; do not confuse with mcrb endonuclease
mcrC protein, E coli: component of mcrbc 5-methylcytosine restriction system; essential to the mcrb restriction system, which is specific for dna containing 5-methylcytosine; encoded by one of the two genes involved in the mcrb restriction system; does not bind dna; see also mcrbc endonuclease; amino acid sequence has been determined
mde2 protein, S. pombe: a forkhead homologue isolated from schizosaccharomyces pombe; has been sequenced
mdg4 protein (gypsy): amino acid ; a mobile genetic element and component of a drosophila chromatin insulator
mdlB protein, E coli: mdl - multidrug resistance-like; gene mdl is closely related to the mdr-encoding genes of eukaryotes; member of the atp-binding cassette (abc) transporter superfamily; genbank l08627
mdlc protein, Drosophila: required to maintain neuronal differentiation; refseq nm_142608
mdm33 protein, S cerevisiae: the inner membrane protein controls mitochondrial morphology in yeast
mead ethanolamide: an eicosanoid; an agonist for the central and peripheral cannabinoid receptors
meadowfoam oil: seed oil of meadowfoam (limnanthes alba) containing over 95% of the fatty acids are 20- and 22-carbon aliphatic acids with cis double bonds located principally at the 5- and/or 13-position
meayamycin: inhibits pre-mrna splicing; has antineoplastic activity
mebezonium: rn given refers to diiodide; rn for parent cpd not available 5/89
mebhydroline: see also rcored for mebhydrolin 1,5-naphthalenedisulfonate, rn: 6153-33-9
mec-8 protein, C elegans: has two rna recognition motifs, regulates alternative splicing of unc-52 transcripts; amino acid sequence given in first source; genbank x95608-9
mecA protein, Bacillus subtilis: do not confuse with meca gene for methicillin resistance in staphylococci; amino acid sequence given in first source; a negative regulator of genetic competence; genbank l06059
mecA protein, Staphylococcus aureus: mediates methicillin resistance; has been sequenced
mecB protein, Bacillus subtilis: negative regulator of genetic competence; a member of the clpc atpase family; isolated from bacillus subtilis; amino acid sequence given in first source; genbank u02604
mecR1 protein, Staphylococcus aureus: methicillin resistance mecr1 protein; encodes a signal transducer; has been sequenced; also found in staphylococcus epidermidis
mechano-growth factor, mouse: refseq nm_001111274.1; np_001104744.1
mechercharmycin A: has antineoplastic activity; isolated from thermoactinomyces
mechercharmycin B: has antineoplastic activity; isolated from thermoactinomyces
mecloqualone: minor descriptor (72-86); on-line & index medicus search quinazolines (72-86); rn given refers to parent cpd
meclorisone dibutyrate: rn given refers to (11beta,16alpha)-isomer
meconic acid: most alkaloids from opium are present in form of meconates; meconic acid is strictly peculiar to opium; from papaver
medami: diaminostilbene sulfonic acid derivative; uv fluorescent dye available as felt tipped marker
medecamycin: macrolide antibiotic which exhibits antibacterial actiivity against gram-positive bacteria
mediatophore: mw approx. 210 kd; isolated from the presynaptic plasma membranes in the electric organ of torpedo marmorata
medicagenic acid: aglycone constituent of lucerne saponins, upon which their fungastatic & hemolytic activity depends
medicagenic acid-3-O-glucopyranoside: isolated from alfalfa roots; ; rn given refers to (2beta,3beta,4alpha)-isomer
medicago-saponin P(1): isolated from the aerial parts of medicago polymorpha
medicago-saponin P(2): isolated from the aerial parts of medicago polymorpha
medikhronal: a ukrainian compound; composed of glucose, glycine, and formate 5:2:1 ratio
mediomycin A: polyene antibiotic from streptomyces mediocidicus atcc23936
mediomycin B: polyene antibiotic from streptomyces mediocidicus atcc23936
medioresinol: has both leishmanicidal and antifungal activities; isolated from sambucus williamsii
mediterraneol A: from cystoseira mediterranea; rn from chem abstr index guide 1990; rn given refers to (1r-(1alpha,6alpha,7beta(e))-isomer; rn for cpd without isomeric designation not avail 7/91
medullipin I: vasodepressor lipid extracted from renal papilla, renomedullary cells grown in monolayer culture & renal venous effluent after uncliping goldblatt hypertensive rat
medullipin II: liver transforms medullipin i to medullipin ii; the primary reno-medullary antihypertensive hormone
mefexamide: proposed psychotherapeutic agent with stimulatory action; minor descriptor (76-83); on-line & index medicus search glycolates (76-83)
mefloquine-sulfadoxine-pyrimethamine: combination of mefloquine, sulfadoxine, pyrimethamine
mefuparib hydrochloride: poly(adp-ribose) polymerase inhibitors
mefway: a 5-ht(1a) receptor radioligand for pet imaging
megacin Cx: bactericidal protein released into medium during growth by bacillus megaterium strain 337; rn in chemline for megacin unspecified: 9010-73-5; rn for megacin fw 337: 57285-15-1
megakaryocytic acute leukemia protein, mouse: a serum response factor (srf) co-activator; do not confuse with mal protein, mouse; genbank bc054801
megalinbinding protein, mouse: a tetratrico peptide repeat-containing adaptor molecule that associates with the receptor; amino acid
megalomycin C: isolated from micromonospora megalomicea; active against hsv-1 and swine fever virus
megapoietin protein, Ovis aries: regulates megakaryocyte growth and platelet production; has been sequenced
megascoliakinin: bradykinin-like cpd from venom of megascolia flavifrons fab
megastigma-6,7-dien-3,5,9-triol 9-O-glycopyranoside: isolated from rosa damascena
megistonine I: isolated from the bark of sarcomelicope megistophylla
megistonine II: isolated from the bark of sarcomelicope megistophylla
megistoquinone I: quinoline alkaloid from the bark of sarcomelicope megistophylla (rutaceae)
megistoquinone II: quinoline alkaloid from the bark of sarcomelicope megistophylla (rutaceae)
meglumine-eicosapentaenoic acid formulation: a soluble omega-3 fatty acid formulation that acts synergistically with epirubicin and mitomycin to enhance cytotoxicity towards bladder cancer cell lines
megopsin1 protein, Megoura viciae: an opsin from the vetch aphid, megoura viciae; 378 amino acid residues; amino acid
megopsin2 protein, Megoura viciae: an opsin from the vetch aphid, megoura viciae; 371 amino acid residues; amino acid
megs protein, Xenopus: xmegs gene is expressed in xenopus germ line; genbank ab066589
mei-218 protein, Drosophila: required for both meiotic crossing over & production of recombination nodules; amino acid sequence given in first source; genbank u35631
mei2 protein, S pombe: required for initiation of premeiotic dna synthesis; isolated from s. pombe; has been sequenced
meiotic factor protein, Coprinopsis cinerea: from coprinus cinereus; mw 30 kda; enhances activity of meiotic dna polymerase from coprinus; amino acid sequence has been determined
meiotic recombination protein SPO11: a meiosis-specific protein that functions as a dna transesterase
meizothrombin: precursor of alpha-thrombin in the conversion of prothrombin to alpha-thrombin; has esterase activity; meizothrombin-(des f1) produced by reaction of prethrombin-1 with echis carinatus venom
mek-1 protein, C elegans: refseq nm_001029600.4
mekratin: a 26 kda hamster skeletal muscle neutral protease that cleaves myosin lc2; 63-85% identity with rat & mouse mast cell proteases; amino acid ; genbank af020767
melagatran: rn refers to (r-(2s))-isomer; ximelagatran is a prodrug that is hydroxylated to melagatran as active thrombin inhibitor
melain: from the sarcocarp of bead tree fruit melia azedarach; mol mass approx 25,000; contains a carbohydrate moiety; enzymatic properties similar to phytolacain
melamine deaminase: catalyzes the sequential conversion of melamine to ammeline and ammelide; about 98% homologous to the enzyme atrazine chlorohydrolase (atza)
melanin concentrating hormone precursor (109-129)-glycyl-glutamic acid: has been sequenced; derived from rat melanin-concentrating hormone precursor
melanin precursors: excreted into culture medium by tetrahymena thermophila mutant where spontaneous polymerization occurs
melanin-associated antigen, rat: mw 22 kda; the tolerance to maa antigen in autoimmune uveitis is mediated by cd4+cd25+ t-regulatory cells; amino acid sequence known
melanin-concentrating hormone: found in fish pituitaries and in rat hypothalamus; heptapeptide melanosome hormone
melanin-concentrating hormone gene-related peptide, tilapia: directly precedes melanin-concentrating hormone (mch) in the prohormone; mch and mgrp are colocated in the hypothalamus and pituitary of tilapia; 22 amino acids in length; amino acid sequence known
melanin-concentrating hormone precursors: contains 132-amino acid residues; two forms are known, both share 107 amino acid residues; amino acid ; rn refers to pre-pro-mch-2 isomer; genbank af064698 (human)
melanin-concentrating-hormone precursor (129-145)-glutamyl-isoleucinamide: has been sequenced; derived from rat melanin-concentrating hormone precursor
melanin-concentrating-like peptide: cyclic heptadecapeptide similar, but not identical to melanin concentrating hormone; found in rat brain
melanocidin A: 5'-nucleotidase inhibitor; from nocardioides sp.1681 j
melanocidin B: 5'-nucleotidase inhibitor & active against melanoma b16; from nocardioides sp. 1681 j
melanocortin 5 receptor: belongs to the melanocortin receptor family; responds mainly to alpha-melanocyte-stimulating hormone (msh); contains 325 amino acid residues; amino acid sequence given in first source; genbank x76295
melanodiol: isolated from a botanical dietary supplement ingredient, dried black chokeberry (aronia melanocarpa) fruit juice
melanodiol 4'-O-protocatechuate: isolated from a botanical dietary supplement ingredient, dried black chokeberry (aronia melanocarpa) fruit juice
melanogen: precursor of melanin; degradation product of tyrosine; present in patas monkey urine, which when left standing, oxidizes to melanin
melanoma-associated cell surface protein, 55-kDa, human: mr 55,000 surface protein implicated in melanoma progression; plays a functionally important role in determining metastasis
melanoma-associated proteoglycan antigen, human: monoclonal anti-idiotypic antibodies to above protein were generated & characterized
melanophore-dispersing hormone: have been sequenced; crustacean neuro-octadecapeptide; found in melanophores; release may be triggered by norepinephrine; drph is referred to as alpha-pdh; beta-pdh has asp in place of glu at postion 17
melanoproteins: melanoproteins are non-covalently bonded associations of melanin and melanosomal proteins, i.e. secondary interactions between melanin and protein
melanopsin: expressed in melanophores, brain, and eye of xenopus laevis; genbank af014797
melanosomal protein, 66-kDa, human: an abundant skin protein; partial amino acid
melanosomal protein, 66-kDa, murine: an abundant skin protein; amino acid sequence known
melanotan-II: synthetic cyclic heptapeptide, an analog of alpha-melanotropin (4,10); capable of stimulating melanin synthesis & promoting rapid tanning of skin; currently in trials for use in the prevention of sunlight-induced skin cancer
melanoxadin: inhibits melanin biosynthesis; isolated from trichoderma sp. atf-606
melanoxazal: isolated from the fermentation broth of trichoderma; inhibits melanin synthesis
melarsen: product of the decomposition in aqueous solution of melarsamine hcl; rn given refers to di-na salt
melastin protein, Streptomyces: immunomodulator isolated from streptomyces; selectively inhibits leukemia cell growth; aa composition in first source
melatonin deacetylase: enzyme from various vertebrate ocular tissues converts melatonin to 5-hydroxytryptamine
meleagrin: low molecular weight protein found in turkey (meleagris gallopavo) ovomucoid preparation; amino acid sequence given in first source
meleagrin alkaloid: an antifouling agent; isolated from penicillium meleagrinum
melectin: isolated from the venom of the cleptoparasitic bee melecta albifrons
meliacin: plant inhibitor isolated from melia azedarach l; induces in cells a refractory state to virus infection
melianodiol: from stem of raulinoa echinata cowan (rutoideae)
melianone: from stem of raulinoa echinata cowan (rutoideae)
melianoninol: from melia azedarach l.; ; rn given refers to (2r-(2alpha(e),3alpha))-isomer; rn for cpd without isomeric designation not avail 3/92
meliavolkenin: isolated from the root bark of melia volkensii; has an apotirucallane skeleton
melibiosyl-phosphatidylethanolamine: synthetic glycophospholipid
melibiosylceramide: ceramide dihexoside isolated from eggs of sea urchin anthocidaris crassispina
melissoidesin: antiacetylcholinesterase and antioxidant ent-kaurene diterpenoid from isodon wightii (bentham) h. hara
melissoidesin G: has antineoplastic activity against leukemia; isolated from the chinese medicinal plant isodon melissoides
melittin(8-26): does not possess lytic properties; forms stable monolayers at air-water interface
melittin-related peptide, Rana tagoi: has antimicrobial and cytolytic activities; amino acid
mellitic dianhydride: hemoglobin modified with above cpd has possible application as a blood substitute
melochinine: from melochia pyramidata l.; causes cattle paralysis; rn given refers to (r)-isomer
melonin protein, Cucumis melo L.: translational inhibitor from the seeds of cucumis melo l.; mr = 23,500; partial structural characteristics have been determined - n-terminal amino acids are blocked and digestion of melonin with trypsin yielded a collection of peptides ( 2 have been sequenced); no further info available 2/93
melotenine A: has antineoplastic activity; isolated from melodinus tenuicaudatus
melrilimab: human monoclonal immunoglobulin g2 (igg2) sigma antibody that binds domain 1 of the cell surface il-33r
melrubiellin A: has antineoplastic activity; isolated from melandrium firmum
melrubiellin B: has antineoplastic activity; isolated from melandrium firmum
membrane and microfilament-associated protein p58, rat: a 58-kda membrane- and microfilament-associated protein; from ascites tumor cell microvilli; has sequence similarity to retroviral gag proteins; refseq nm_139039
membrane glycoprotein antigen GP22, Schistosoma: from schistosoma mansoni; amino acid sequence has been determined
membrane glycoprotein gp42, rat NK cell: amino acid sequence given in first source; cell-surface molecule that is selectively induced on rat nk cells by il-2; rn given is for product of clone 1
membrane nuclease MnuA protein, Mycoplasma pulmonis: mnua - membrane nuclease a; 470 amino acid residues, mw 54 kda; from mycoplasma pulmonis; genbank u38841
membrane steroid binding protein, lens: steroid binding membrane protein expressed in lens epithelial cells; amino acid
membrane-associated PGE synthase, rat: vascular endothelial growth factor increases messenger rnas encoding this enzyme in rat luteal cells
membrane-associated PGE synthase-1, rabbit: colocalizes with both cox-1 and cox-2 to mediate the biosynthesis of pge2 in the kidney; amino acid
membrane-associated factor, rat: stimulates levels of substance p and choline acetyltransferase in sympathetic neurons; mw 29 kda
membrane-associated placental tissue protein 1: glycoprotein with mw 180 kd
membrane-bound adrenal trypsin-like enzyme: putative processing enzyme for proenkephalin with activity directed twoard basic residues; cleaves between & following the paired basic residues at positions 23 & 24 of peptide b(thus generating (met-enkephalin)-arg-phe & arg-(met-enkephalin)-arg-phe)
membrane-bound proton-translocating PPi synthase: from rhodospirillum rubrum; functions as an alternative coupling factor; n,n'-dicyclohexylcarbodiimide-sensitive; catalyzes the phosphorylation of pi to ppi, the hydrolysis of ppi & the concomitant translocation of proton across the plasma membrane
membrane-bound transcription factor peptidase, site 1: cleaves the endoplasmic reticulum loop of srebp transcription factors
membranolide B: diterpene from the antarctic sponge dendrilla membranosa
membrenone A: a dihydropyrone-containing marine natural product from skin of a mediterranean mollusc
membrenone B: a dihydropyrone-containing marine natural product from skin of a mediterranean mollusc
membrenone C: a dihydropyrone-containing marine natural product from skin of a mediterranean mollusc
memnopeptide A: a terpene peptide from memnoniella with an activating effect on serca2
men-9 protein, Silene latifolia: men - male enchanced; involved in establishing third floral whorl of silene latifolia; gene appears to encode two forms, men-9a and men-9b, which are 85.4% identical; amino acid ; genbank y12324 (men-9a) and y12325 (men-9b)
menadione alkyltransferase: catalyzes the transfer of an alkyl group from an alkylpyrophosphate to a position ortho to one of the keto groups of menadione
menecubebane A: from the hainan gorgonian menella kanisa grassoff
menecubebane B: has antineoplastic activity; isolated from menella, a gorgonian coral
menf.1 protein, Xenopus: involved in ventral mesoderm induction; genbank af536830
meningobactin: low mw iron-reactive siderophore from neisseria meningitidis which enables parasite to compete successfully with host's iron-sequestering mechanisms
meningococcal group C polysaccharide-tetanus toxoid conjugate: meningococcal group c polysaccharide chemically reacted with tetanus toxoid
meningococcal type B conjugate vaccine: main component is n-propionylated group b meningococcal polysaccharide (npr-gbmp) attached to a carrier protein
menisporopsin A: antimalarial macrocyclic polylactone, from the fungus menisporopsis theobromae
menisporopsin B: has antimalarial activity; isolated from menisporopsis theobromae
menoprogen: derived from five herbal extracts; based on an ancient royal recipe; used to treat menopausal symptoms
menthofuran: rn given refers to cpd without isomeric designation; derives from cyclization of pulegone
menthol glucuronide: rn given refers to (1r-(1alpha, 2beta, 5alpha)-isomer
menthyl 3-(2-pyridylsulfinyl)acrylate: ; used to produce a carbocyclic analog of showdomycin
menthyl chloroformate: rn given refers to (1r-(1alpha,2beta,5alpha))-isomer
mepazine: major descriptor (66-85); on-line search phenothiazines (66-85); index medicus search mepazine (66-85); rn given refers to parent cpd
mepenzolic acid: anticholinergic, antispasmodic agent; rn given refers to parent cpd
mephenoxalone: minor descriptor (65-86); on-line & index medicus search oxazoles (66-86)
mepiprazole: psychotropic agent; tranquilizer in schizophrenia; possible chronobiotic agent for therapy in circadian rhythm desynchronization; rn given refers to parent cpd; rn for emd 16923 with mf unknown: 52499-69-1
mepitiostane: orally active anti-estrogenic steroid; rn refers to (2alpha,3alpha,5alpha,17beta)-isomer
meplazumab: anti-cd147 antibody that blocks sars-cov-2 entry
mepolizumab: a humanized monoclonal antibody to il-5 in cynomolgus monkeys
mepregenol diacetate: tested for use in combination with ethinyl estradiol; rn given refers to (3beta)-isomer
meprin A: from renal microvillar membrane; contains zinc; distinguished from ec 3.4.24.11 by insensitivity to phosphoramidon; meprin b is a separate record 10/95; do not confuse with meprin (synonym to mercaptopropionylglycine used in the treatment of liver diseases, as a detoxicant & in therapy of myopia); composed of disulfide-bridged dimers of alpha-subunits; refseq nm_005588 (mep1a, human); nm_008585 (mep1a, mouse); nm_013143 (mep1a, rat); nm_005925 (mep1b, human); nm_008586 (mep1b, mouse); nm_013183 (mep1b, rat)
meprin B: a heterodimer of alpha- and beta-subunits; amino acid sequence has been determined
merC protein, Acidithiobacillus ferrooxidans: from thiobacillus ferrooxidans; plays role in mercury transport; amino acid sequence given in first source; there are two merc, genes merc1 & 2; rn refers to merc1; do not confuse with raly/merc mouse protein
merD protein, bacterial: amino acid sequence given in first source; 121 amino acid residues; involved in regulation of expression of mercury resistance
mercaptide V: formed from 2 mol thiosalicylate & 1 mol hg++; proposed
mercapto-(2-thienyl)acrylic acid: used as a chelating agent
mercaptoacetyl polyethyleneimine: for removal of turbidity in wastewater
mercaptomerin: rn given refers to parent cpd; structure in merck index, 9th ed, #5700
mercaptomethyl-4-methylpentanoyl-phenylalanylalaninamide: inhibits pseudomonas aeruginosa elastase & keratitis
mercaptopropionylhydrazide: reagent for introducing sulfhydryl groups into proteins
mercaptoundecahydrododecaborate: agent used for the boron-neutron capture therapy of brain tumor; incorporated selectively into malignant tissue; rn given refers to parent cpd
mercenene: growth inhibiting, antitumor substance isolated from edible clam, the quahog (mercenaria mercenaria); no other info available 8/74
mercryl lauryle: combination of mercurobutol & sodium lauryl sulfate with excipients
mercurated dUTP: a heat- and thiol-stable, mercurated derivative of deoxyuridine triphosphate
mercurial-insensitive water channel: a mammalian channel; amino acid sequence given in second source
mercuric acetate: rn given refers to cpd with mf of hg-(c2h4o2)2
mercuric iodide, red: single cyrstals of hgi2 are used as room temp semiconductor x-ray detectors for application to computed tomography
mercuric reductase: reduces hg2+ to volatile hg, contains fad, requires nadph
mercuric sulfate: rn given refers to cpd with mf of hgso4
mercurophylline: combination of na salt of mercamphamidum & theophylline
mercury transport protein, bacterial: an hg(2+)-transport protein from pseudomonas; has been sequenced
mercury-selenium complex: complex formed when sodium selenite is injected into blood containing inorganic mercury; important for mercury poisoning detoxification
merlin, Drosophila: the gene referred to in flybase as "mer" (fbgn0041733) is not the same gene as that referred to in flybase as "mer" (fbgn0086384) - they are on different chromosomes
merocyanine dye: fluorescent dye used for studying axons 2 position on pyrimidine ring may be s or o; rn given refers to na salt
merocyclophane C: from the cultured freshwater cyanobacterium nostoc sp.
merocyclophane D: from the cultured freshwater cyanobacterium nostoc sp.
meromycolic acids: subgroup of mycolic acids having cyclopropane rings at 2 points along an extended carbon chain
merozoite major surface antigen, Plasmodium: from plasmodium falciparum; very immunogenic in humans & is considered a candidate for developing a malaria vaccine
merozoite surface antigen p58, Babesia: from babesia bigemina; candidate immunogen for inclusion in an antigenically defined vaccine; amino acid sequence given in first source
merozoite surface protein 3, Plasmodium: mw 48 kda; partial amino acid
merozoite surface protein 3beta: isolated from plasmodium vivax; genbank af099662
merozoite surface protein 3gamma: isolated from plasmodium vivax; genbank af099663
merozoite surface protein 4, Plasmodium: amino acid ; genbank af080446-7
merozoite surface protein 5: isolated from plasmodium falciparum; amino acid ; genbank af033037; do not confuse with msp5 protein
merozoite surface protein 6, Plasmodium: msp-6(36) is the 36-kda protein derived from a precursor, which is known in the first source as msp-6; isolated from plasmodium falciparum; genbank ay007721
merozoite surface protein 7, Plasmodium: gene is expressed in mature schizonts; 351 amino acid residues, mw 41 kda; from p. falciparum; genbank af390150-3
merozoite surface protein 9, Plasmodium: from plasmodium falciparum; involved in the merozoite invasion of erythrocytes; amino acid ; genbank af435853, af435854, af435855
merrekentrone C: from the roots and rootstocks of merremia kentrocaulos
mersacidin: a globular type b lantibiotic; peptide isolated form a bacillus species
mersyndol: combination of above cpds; used as an analgesic in temporomandibular joint pain dysfunction syndrome
merthiolate-iodine-formalin fixative: formed by mixing iodine solution with merthiolate-formalin solution immediately before use; used to fix protozoan cysts, helminth eggs & larvae
meru protein, Drosophila: rassf9/rassf10 homolog involved in cell polarity establishment; genbank bt009993
merulin A: cytotoxic compound from the culture broth extract of an endophytic fungus of xylocarpus granatum
merulin B: from the culture broth extract of an endophytic fungus of xylocarpus granatum
merulin C: cytotoxic compound from the culture broth extract of an endophytic fungus of xylocarpus granatum
mesangial matrix antigen: from rat glomerulus; present exclusively in the mesangium; mw 81,000
mesedin: an alpha2 adrenoblocker; has neuroprotective and neurogenic effects on cultured astroglial cells
mesenchyme fork head 1 protein: member of the fork head domain family, expressed in developing mesenchyme in mouse; refseq nm_005251 (human), nm_013519 (mouse)
mesenchyme-derived growth factor: mw 70-76kda; stimulates proliferation of mammary epithelium from adult mice
mesentericin Y 105(37): has an additional tryptophan residue at the c-terminus of mesentericin y105, making it a 37-amino acid residue peptide with profound influence on the activity; amino acid sequence given in first source
mesentericin Y105 protein, Leuconostoc mesenteroides: anti-listeria bacteriocin from leuconostoc mesenteroides; displays bactericidal mode of action; mw 2.5-3.0 kda; amino acid sequence given in first source
mesityl oxide: solvent for extraction of nitrocellulose, many resins, & tellurium
mesitylene sulfonyltetrazole: sulfonation agent; rn & n1 from 9th ci form index
meso-(rel 7S,8S,7'R,8'R)-3,4,3',4'-tetrahydroxy-7,7'-epoxylignan: antioxidant lignan from larrea tridentata
meso-2,3-dimethyl-1,4-bis(3,4-(2-(piperdino)ethoxyphenyl))butane tetrakishydrochloride: anti-hiv agent
meso-chlorin e(6) monoethylene diamine: rn given for (2s-trans)-isomer
meso-tartrate dehydrogenase: forms dihydroxyfumarate; distinguished from ec 1.1.1.93 which forms oxaloglycollate
meso-tetra(o-benzoylaminophenyl)porphyrin: structutre in first source
meso-tetra-(4-hydroxyphenyl)porphyrin: used for photodynamic therapy
meso-tetrakis (4-N,N,N-trimethylanilinium) porphyrin: a water-soluble cationic porphyrin
meso-tetrakis(4-trimethylammoniumphenyl)porphyrin: a photosensitizing agent
meso-tetrakis(p-sulfonatophenyl)N-confused porphyrin: a photosensitizing agent
meso-tri(N-methyl-pyridyl)mono(N-dodecyl-pyridyl)porphine: a photosensitizing agent used in photodynamic therapy to treat malaria
mesoderm specific transcript protein: peg - paternally expressed gene (on human chromosome 7); mouse & human proteins are highly homologous; expressed in all major fetal organs & tissues
mesoporphyrin IX: rn given refers to parent cpd; mesoheme is the iron salt of mesoporphyrin ix
mesotocin receptor: expressed in prostate gland of the tammar wallaby macropus eugenii; amino acid
mesotrione: brandname is after the callistemon (myrtaceae) plant it was found in
mesoxalonitrile: minor descriptor (75-83); on-line & index medicus search nitriles (75-83)
mesquite pollen peptidase II(mes): isolated from prosopis velutina; specific for hydrophobic amino acids such as phenylalanine; also has oligopeptidase activity towards vip, angiotensin ii and angiotensin i
mesquitol-(4alpha-5)-3,3',4',7,8-pentahydroxyflavonone: from acacia nigrescens (leguminosae)
mesulergine: rn given refers to parent cpd; cu 32-085 is synonymous to mono-hcl; metabolized into dopaminergic agonists
mesylphenacyrazine: rn given refers to maleate[1:1]
metW protein, Pseudomonas syringae: involved in methionine biosynthesis; isolated from pseodomonas syringae; amino acid
meta-3,3',3'',3'''-(carbonylbis(imino-5,1,3-benzenetriylbis(carbonylimino)))tetrakisbenzenesulfonic acid: a p2x receptor antagonist
meta-carborane-1-carboxylic acid: used for synthesis of carboranyl esters
meta-carborane-butyl-3-(3-pyridinyl)-2-propenamide: used to treat sepsis and pulmonary inflammation
metabisulfite: see also related na metabisulfite & k metabisulfite
metabotropic glutamate receptor 3: from mammalian brain; rat & human receptors are 97% homologous; amino acid sequence given in first source; genbank x77748
metabotropic glutamate receptor 4: a group iii metabotropic glutamate receptor
metabotropic glutamate receptor 6: a group iii metabotropic glutamate receptor; the molecularly cloned mglur6 is restrictedly expressed at the postsynaptic site of on-bipolar cells in both rod and cone systems
metabotropic glutamate receptor 7: a group iii metabotropic glutamate receptor; isolated from medulla; rat & human receptors are 92% homologous; amino acid sequence given in first source; genbank x94552
metabotropic glutamate receptor 8: a group iii metabotropic glutamate receptor; amino acid
metabotropic glutamate receptor type 1: do not confuse with glur1 protein
metacaspase 9, Arabidopsis: genbank ay219834 (precursor)
metachromin A: from a taiwanese marine sponge, hippospongia metachromia
metachromin B: from a taiwanese marine sponge, hippospongia metachromia
metachromin E: from a taiwanese marine sponge, hippospongia metachromia
metachromin U: cytotoxic merosesquiterpenoid from an australian sponge, thorecta reticulata
metachromin V: cytotoxic merosesquiterpenoid from an australian sponge, thorecta reticulata
metachromin W: cytotoxic merosesquiterpenoid from an australian sponge, thorecta reticulata
metacridamide A: from conidia of the entomopathogenic fungus metarhizium acridum
metacridamide B: from conidia of the entomopathogenic fungus metarhizium acridum
metacyclogenin, Trypanosoma cruzi: gene is specifically expressed during metacyclogenesis; genbank af175290, af363239
metadizine: an alkoxy-xylidide derivative; no other info avail 8/90
metafectene: liposomal reagent for gene delivery, superior to lipofectamine in the transfection of g(s) alpha prostate cancer cells
metahalones: group of 5-halogen-pyrimidin-2-ones with metaphase-arresting activity
metahexamide: major descriptor (64-83); on-line search sulfonylurea compounds (64-83); index medicus search metahexamide (64-83); rn given refers to parent cpd
metallo-beta-lactamase L1, Stenotrophomonas maltophilia: secreted by pathogenic s maltophilia; a dinuclear zn(ii)-containing enzyme that hydrolyzes almost all known penicillins, cephalosporins, and carbapenems; the presence of zn(ii) ions in both metal binding sites is essential for full enzymatic activity
metallo-beta-lactamase, IMP-10: a variant metallo-beta-lactamase, imp-10, from two unrelated strains of pseudomonas aeruginosa and an alcaligenes xylosoxidans strain
metallo-gamma-lactonase: lactone-hydrolyzing enzyme derived from bacillus species is capable of disrupting quorum sensing in bacteria that use n-acyl-l-homoserine lactones (ahls) as intercellular signaling molecules
metallocarboxypeptidase D: a host cell glycoprotein encoded by a member of the carboxypeptidase gene family that binds duck hepatitis b virus particles; refseq nm_012836 (rat); nm_001304 (human); nm_007754 (cpd, mouse)
metallocarboxypeptidase Z: amino acid ; genbank u83411 (human)
metalloendopeptidase QG: from e coli; preferentially cleaves gln-gly bond; mw 67 kda; inhibited by tris & imidazole buffers
metallohemoglobin A(0): hb a(0) reconstituted with various metal ions
metallopeptidase-1: isolated from haemonchus contortus; amino acid ; genbank z75054
metalloprotease B, Erwinia chrysanthemi: amino acid sequence given in first source; has some homology to eukaryotic matrix metalloproteinases
metalloproteinase A, Streptomyces coelicolor: amino acid sequence given in first source
metalloproteinase inhibitor, Streptomyces: 102 amino acids from streptomyces nigrescens
metalloproteinase inhibitor, bovine aortic endothelial cells: amino acid sequence given in first source; related to tissue inhibitor of metalloproteinases (timp)
metalloselenonein: contains selenocysteine residues substituted for all cysteine residues in neurospora crasa copper metallothionein; amino acid sequence given in first source
metallothionein II hexacosapeptide 36-61: c-terminal hexacosapeptide corresponding to residues 36-61 of human liver metallothionein ii
metallothionein isoform 1: metallothionein isoform gene, downregulated in advanced prostate cancer; has been sequenced
metallothionein-4, mouse: distributed in a tissue-specific manner, mainly in stratified squamous epithelia; amino acid
metallothionein-like protein, Brassica campestris: isolated from brassica campestris; has been sequenced; genbank l31940
metamorphosin A: induces metamorphosis of posterior portions of hydractinia echinata; amino acid
metanephros-derived tubulogenic factor, human: putative ribosomal protein that promotes ureteric bud branching in the metanephros; genbank aag01157
metanephros-derived tubulogenic factor, mouse: putative ribosomal protein that promotes ureteric bud branching in the metanephros; genbank xp_130843
metanestin protein, human: a 60 kda glycoprotein with metastasis-associated expression in transitional cell carcinoma of the urinary bladder; amino acid sequence given in first source
metanx: a preparation of methylcobalamin, pyridoxal phosphate, and l-methylfolate for treatment of endothelial dysfunction
metaphase chromosome protein 1, human: the human autoantigen mcp1 is required during early stages of dna replication & is associated with condensed chromosomes throughout mitosis
metarhizin A: a cytochrome c oxidase inhibitor with antiproliferative activity; isolated from metarhizium flavoviride
metariboadenosine triphosphorous: eyedrops of atp, riboflavin & methyluracil combination
metarrestin: a first-in-class small molecule clinical candidate capable of disrupting the perinucleolar compartment, a subnuclear structure unique to metastatic cancer cells
metasequirin B: isolated from the heartwood of metasequoia glyptostroboides
metastasis-associated kinase, Xenopus: modulates wnt signaling during morphogenetic movements; amino acid
metavinculin: metavinculin has 68 additional amino acids compared to vinculin; mw 123 kda; sequence known
metepa: minor descriptor (72-82); online & index medicus search azirines (72-82)
metflurazon-N-demethylase: a cytochrome p-450 monooxygenase; mediates the n-demethylation of the pyridazinone herbicide metflurazon to form norflurazon and san 9774
methacrylaldoxime-O-methyl ether: volatile catabolite of valine
methacrylonitrile: lacrimator; preparation of polymers & homopolymers
methacryloxylethyl cetyl dimethyl ammonium: hinders biofilm formation
methacryloyloxydodecylpyridinium bromide: incorporated into composite resins for inhibiting dental caries and plaque accumulation
methamilane methiodide: muscarinic agonist; rn given refers to iodide without isomeric designation
methanandamide: ; rn given refers to (all-z)-(+-)-isomer
methane monooxygenase: mmoc encodes protein c of soluble methane monooxygenase (smmo); pmmo (membrane-associated methane monooxygenase) contains 4 moles of nonheme iron and 1 mole of copper per mole enzyme complex
methanesulfonate sulfonatase: a flavin mononucleotide-dependent enzyme that catalyzes the desulfonation of alkanesulfonates; genbank af026067
methanesulfonic acid monooxygenase: catalyzes conversion of methanesulfonic acid to formaldehyde and sulfite; requires nadh; consists of a, b, and c components; component c is an iron-sulfur protein
methanethiosulfonate: used for measurement of rhodanese activity; rn given refers to parent cpd
methanobactin: binds copper; isolated from the methane-oxidizing bacterium methylosinus trichosporium
methanochondroitin: a heteropolysaccharide from cell wall which resembles the eukaryotic chondroitin
methanol extraction residue (MER) tubercle bacillus fraction: extract of phenol killed, acetone washed tubercle bacilli (bcg attenuated)
methanol oxidase: contains fad and flavin semiquinone; from the yeast hansenula polymorpha
methanol-2-mercaptoethanesulfonic acid methyltransferase: catalyzes first reaction in conversion of methanol to methane by methanosarcina barkeri; 24-kda subunit mtac and 49-kda subunit mtab of mt1 corrinoid protein have been sequenced; genbank y08310
methanotetramethrin: cis-tetramethrin analog with 2-methyl-1-propenyl group replaced by 2,2-dimethylcyclopropyl group
metharbital: was heading 1976-94 (see under barbiturates 1976-90); endiemal, metharbitone, & methobarbitone were see metharbital 1976-94; use barbiturates to search metharbital 1976-94; long-acting barbiturate that is demethylated to barbital in the liver; has broad-spectrum anticonvulsant action, but used mainly to treat myoclonic spasms in infants
methenamine mandelate: 'reflux' is dagra brand name which is not kept as term due to low use and other meanings of the term
methenyltetrahydromethanopterin cyclohydrolase: from methanobacterium thermoautotrophicum; catalyzes the energy-independent hydrolysis of 5,10-methenyl-5,6,7,8-tetrahydromethanopterin to 5-formyl-h4mpt
methidathion: widely used on citrus, tobacco, alfalfa, cotton, sorghum & several other crops
methimidol: leptospirocidal agent; rn given refers to parent cpd
methiocarb sulfoxidase: sulfide is oxidized to sulfoxide; from microsomes of soybean cotyledons; did not require nad(p), fad of cytochrome p450 cofactors
methiodal: major descriptor (66-86); on-line search methanesulfonates (74-86), alkyl sulfonates (73), sulfonic acids (66-72); index medicus search methiodal (66-86)
methione-equine growth hormone: methionine attached to the n-terminal end of equine growth hormone; administered to racehorses as a doping agent
methionine S-methyltransferase: catalyzes synthesis of s-methylmethionine from l-methionine and s-adenosylmethionine
methionine aminopeptidase 2: highly conserved between human & yeast; binds fumagillin; distantly related to metap-1; partial amino acid sequence given in first source
methionine decarboxylase: from fern dryopteris filix-mas; pyridoxal 5'-phosphate required for activity; converts methionine to 3-(methylthio)propionaldehyde
methionine repressor protein, Bacteria: dimer of 104 amino acid residues per polypeptide chain; required for repression of methionine regulon
methionine repressor protein, E coli: dimer of 104 amino acid residues per polypeptide chain; required for repression of methionine regulon
methionine stromal cell-derived factor-1beta: addition of an n-terminal methionine residue to sdf-1beta
methionine sulfoxide NPY: binds to the cloned y1, y2, y3, y4 and y5 subtypes of the rat npy receptor with high affinity similar to that of npy ; amino acid sequence given in first source
methionine sulfoxide reductase: do not confuse with msra gene product from staphylococcus; refseq nm_026322 (mouse); nm_012331 (human)
methionine synthase reductase: member of fnr family of electron transferases; human enzyme is defective in patients with homocystinuria; refseq nm_024010 (human)
methionine-rich 2S protein, Helianthus: 12.13 kda; 103 amino acid protein; amino acid sequence given in first source
methionyl human consensus alpha interferon: product of gene constructed to code for the most frequent amino acid residues known to occur in subspecies of alpha interferons; the resultant consensus interferon contains 166 amino acid residues with 10 positions different from interferon alpha-f which is the alpha interferon it most closely resembles; first amino acid is replaced by methionine
methionyl-arginyl-histidyl-phenylalanyl-tryptophyl-glycine: synthetic analog of the acth(4-10) core sequence with about 4x the lipolytic activity of the natural sequence; differs from the natural by replacement of glu by the first arg
methionyl-asparagyl-tyrosyl-aspartyl-isoleucine: inhibits o-acetylserine sulfhydrylase
methionyl-aspartyl-phenylalaninamide: c-terminal fragment of gastrin; rn refers to (all-l)-isomer
methionyl-leucyl-cysteinyl-valyl-leucyl-glutaminyl-glycyl-leucyl-arginyl-glutamic acid: increases tolerance to oxidative stress in arabidopsis; prevents copper-induced toxicity in human cells
methionyl-leucyl-phenylalanyl-isoleucyl-lysyl-arginyl-seryl-arginyl-histidyl-phenylalanine: c terminus of middle-sized tumor antigen of polyoma virus; inhibits phospholipases a2, c and d and phosphatidylinositol-specific phospholipase c
methionyl-leucyl-prolyl-histidyl-histidyl-glycyl-alanine: a synthetic peptide that binds hydroxyapatite
methionyl-tyrosyl-lysine: tripeptide from spinal cord & dorsal root of sheep ganglia; rn given refers to (l-met-l-tyr-l-lys)-isomer
methionylmethionine: has growth-promoting ability equal to dl-methionine; rn given refers to (dl-met-dl-met)-isomer
methionylphenylalanine: rn given refers to all (l)-isomer; rn for cpd without isomeric designation not avail 8/92
methiosetin: antibacterial from a tropical sooty mold, capnodium sp.
methisosildenafil: synthetic analog in which the n-methylpiperazine moiety has been replaced with 2,6-dimethylpiperazine
methotrexate transporter protein, mouse: no mouse sequence links or mgd entry (mouse protein likely represents either abcg2 or slc19a1)
methotrexate-GIVGPL-dextran: dextran-peptide-methotrexate conjugate
methotrexate-PVGLIG-dextran: dextran-peptide-methotrexate conjugate
methotrexate-gamma-1,2-dimyristoylphosphatidylethanolamine: vehicle for methotrexate in liposomes; rn given refers to (l)-isomer
methotrexate-gamma-glycerophosphatidylethanolamine: vehicle for methotrexate in liposomes; rn given refers to (l)-isomer
methoxy poly(ethylene glycol)-block-poly(glutamic acid)-graft-6-(2-nitroimidazole) hexyl amine: used to form nanoparticles for carrying doxorubicin
methoxy succinyl-alanyl-alanyl-prolyl-valine-DOPE: a peptide-lipid conjugated with dope
methoxyamericanolide B: isolated from the gorgonian coral pseudopterogorgia americana
methoxyamine: analytical reagent for aldehydes and ketones; strong irritant, can probably produce methemoglobinemia; rn given refers to parent cpd
methoxybenzanthrone: rn given refers to 2-methoxybenzanthrone; rn for 3-methoxybenzanthrone: 3688-79-7
methoxybibenzyl-3, 3'-di-O-beta-D-glucopyranoside: from the tuber of cremastra appendiculata
methoxybifurcarenone: an antifungal and antibacterial meroditerpenoid from the brown alga cystoseira tamariscifolia
methoxycarbonylethyl 1-(1-phenylethyl)-1H-pyrrole-2-carboxylate: a hypnotic with gaba(a) receptor modulating activity
methoxycarbonyloctyl 3,6-di-O-(2-deoxy-2-(N-acetylamino)glucopyranosyl-(1-2)-6-deoxymannopyranosyl)mannopyranoside: the core of complex n-linked oligosaccharides
methoxycarbonylphenylcyclopentylacetyl-N,N'-dimethyltropinium methyl sulfate: a soft anticholinergic agent
methoxyconidiol: trihomoabietane diterpenoid from plectranthus grandidentatus
methoxyflurane defluorinase: metabolizes methoxyflurane, isoflurane or enflurane enzyme induction with phenobarbital to inorganic fluorides;
methoxyluteolin: inhibits tnf gene expression and secretion by cultured mast cells
methoxymelanin: formed from 6-hydroxymelatonin by microsomes; rn & n1 from ca vol 92 form index
methoxymethyl-3-((2-methyl-1,3-thiazol-4-yl)ethynyl)pyridine: binds mglu5 receptors
methoxyneurosporene dehydrogenase: amino acid sequence given in first source; involved in later stages of carotenoid biosynthesis
methoxyresorufin-O-demethylase: a monooxygenase that is supported by both p4501a1 and p4501a2
methoxysuccinyl-Ala-Ala-Pro-Phe-chloromethyl ketone: a potent proteinase k inhibitor
methoxysuccinyl-alanyl-alanyl-prolyl-valine chloromethyl ketone: prevents elastase-induced emphysema
methoxythymol acetate: isolated from the leaves of baccharis dracunculifolia
methoxyvinylglycine: a member of a family of nonproteinogenic amino acids featuring an essential vinyl ether conferring mechanism-based inhibition of pyridoxal phosphate enzymes
methsuximide: anticonvulsant effective in petit mal & psychomotor epilepsy; has a number of unpleasant & toxic side effects; minor descriptor (75-86); on-line & index medicus search succinimides (75-86); rn given refers to parent cpd without isomeric designation
methuracol: collagen sponge with 5% methyluracil for local application on deep burns & wounds of the skin
methy-6-hydroxy-11beta-acetoxy-12alpha-(2-methylpropanoyloxy)-3,7-dioxo-14beta,15beta-epoxy-1,5-meliacadien-29-oate: a tetranortriterpenoid from trichilia pallida (meliaceae)
methyl (1-(2-(3-(3-hydroxy-6-isopropyl-4,7-dioxo-5,8-diaza-1(1,4)-benzenacyclododecaphan-10-en-3-yl)propyl)-2-(4-(thiazol-2-yl)benzyl)hydrazinyl)-3,3-dimethyl-1-oxobutan-2-yl)carbamate: an hiv-1 protease inhibitor
methyl (1-(2-(4-(4-(6-(2-(1-((methoxycarbonyl)valyl)pyrrolidin-2-yl)-1H-imidazol-5-yl)quinoxalin-2-yl)phenyl)-1H-imidazol-2-yl)pyrrolidin-1-yl)-3-methyl-1-oxobutan-2-yl)carbamate: a nonstructural protein 5a inhibitor
methyl (1-(5-fluoropentyl)-1H-indazole-3-carbonyl)valinate: synthetic
methyl (2-((7-((7-guanidino-4-(methoxyamino)-2,3-dioxoheptyl)oxy)-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-en-1-yl)-4-oxo-4H-chromen-3-yl)oxy)acetyl)argininate: has antibacterial activity
methyl (3R)-malonyl-(13S)-hydroxycheilanth-17-en-19-oate: from the roots of aletris farinosa
methyl (E)-(3-(3,4-dihydroxyphenyl)acryloyl)tryptophanate: an o-methyl ester of javamide-ii that has anti-inflammatory activity
methyl (E,E)-14,14-dibromo-4,6,13-tetradecatrienoate: protein tyrosine phosphatase-1b inhibitor from chinese marine sponge, xestospongia testudinaria
methyl (N-benzoyl-3'-phenylisoserinate): inhibits t lymphocyte proliferation; also has antineoplastic and antiviral activities
methyl (S)-glycerate: cytotoxic and anti-hiv compound from the rhizomes of begonia nantoensis
methyl (Z)-3-(3,4-dihydroxyphenyl)-2-formamidoacrylate: from marine alga-derived endophytic fungus penicillium oxalicum en-290
methyl 1'-epiacarviosin: inhibits alpha & beta-d-glucosidase & alpha-d-mannosidase
methyl 1,2,3,4-tetrahydro-3-hydroxymethyl-beta-carboline-2-carbodithioate: rn given from toxlit 5/88; rn given refers to (s)-isomer
methyl 1,2,3,6,8,14-hexahydroxy(4,2,1(10,30),1(1,4))tricyclomeliac-7-oate: isolated from khaya senegalensis (meliaceae)