NLK-NML/MeSH-CZ-2025-notes huggingface dataset:
spirotenuipesine A: a spirocyclic trichothecane, isolated from entomopathogenic fungus, paecilomyces tenuipes
spirotenuipesine B: a spirocyclic trichothecane, isolated from entomopathogenic fungus, paecilomyces tenuipes
spirotubipolide: from the formosan stolonifer tubipora musica (stolonifera)
spiruchostatin C: a potent histone deacetylase inhibitor from burkholderia thailandensis
spithioneine A: from a marine-derived streptomyces spinoverrucosus
spithioneine B: from a marine-derived streptomyces spinoverrucosus
spkA protein, Synechocystis: a eukaryotic-type protein kinase, is required for normal motility of the unicellular cyanobacterium synechocystis sp. strain pcc 6803
splase: constructed by genetically fusing the dna-cleavage domain of foki restriction endonuclease with the zinc-finger dna-binding domain of transcription factor sp1; recognizes a 10-bp sequence of the long terminal repeat of hiv-1 dna at sp1 sites and cleaves phosphodiester bonds upstream of thebinding sequence
spleen aminopeptide oral lyophilized powder: consists of peptides and nucleotides extracted from fresh pig spleen
spleen derived immunosuppressive peptide: spleen-derived; depresses humoral response in mice
spleen protease inhibitor II: differs from aprotinin by seven amino acids; has been sequenced
splendipherin: aquatic sex pheromone from a male tree frog, literoia splendida; 25 amino acid residues; amino acid
splenopentin: see also bch 069 which is a modified pentapeptide from splenin
spliceosomal peptide P140: synthetic peptide, sequence 131-151 of the u1-70k protein phosphorylated at ser140, which is recognized by lupus cd4+ t cells for the treatment of patients with systemic lupus erythematosus
splicing endonuclease: cleaves intervening sequences of precursors trna, which are then joined by an rna ligase
splicing factor 3a: sf3a consists of three subunits of 60, 66, and 120 kda; a mammalian protein, 30% identical to yeast prp9; amino acid sequence given in first source; genbank u08815
spn-B protein, Drosophila: member of rad52 dna repair pathway; isolated from drosophila; has been sequenced; refseq nm_057392
spn-D protein, Drosophila: encodes a rad51c-like protein that is required exclusively during meiosis; refseq nm_170321
spn-E protein, Drosophila: required for rna localization in drosophila oogenesis; member of the de-h family of rna-dependent atpases; 1459 amino acids; mw about 155 kda; amino acid sequence given in first source; refseq nm_057393
spns1 protein, zebrafish: a yolk-specific not really started (nrs) gene is a vertebrate homolog of the drosophila spinster gene and is essential for embryogenesis; amino acid ; refseq nm_153663
spo protein, Drosophila: involved in ecdysone biosynthesis; refseq nm_139718
spo0M protein, Bacillus subtilis: involved in sporulation in bacillus subtilis; amino acid
spoIIR protein, Bacillus subtilis: a stage ii sporulation protein r, its necessary and sufficient for triggering processing of pro-sigma(e) in bacillus subtilis; it is 45% homologous to spoiir protein of bacillus halodurans; amino acid sequence has been determined
spoIV protein, Bacillus megaterium: stage iv sporulation protein (spoiv); amino acid sequence given in first source; genbank x75069
spoIVFA protein, Bacillus subtilis: amino acid sequence given in first source; homologous protein found in bacillus halodurans; inhibitor of spoivfb protein
spoIVFB protein, Bacillus subtilis: amino acid ; implicated in the coupling of mother cell to forespore gene experession; required for spore formation; also a probale proteolytic enzyme that processes the pro-sigma k factor; genbank x59528
spoVID protein, Bacillus subtilis: required for the assembly of spore coat in bacillus subtilis; amino acid sequence given in first source; genbank l07792
spoVK protein, Bacillus subtilis: from bacillus subtilis; mw 36 kda; expressed only in mother cell from sequentially active promoters; amino acid sequence given in first source
spoVM protein, Bacillus subtilis: amino acid sequence given in first source; required for normal formation of the cortex and coat during sporulation; genbank no. l12244
spok protein, Drosophila: involved in ecdysone biosynthesis; has been sequenced; refseq nm_001110990
spongia-13(16),14-dien-3-one: from nudibranch mollusk glossodoris atromarginata
spongiacidin C: alkaloid from the marine sponge stylissa massa, functions as a usp7 inhibitor
spongiadioxin C: a minor polybrominated dibenzo-p-dioxin from an australian marine sponge dysidea dendyi
spongiadioxin C, methyl ether: a minor polybrominated dibenzo-p-dioxin from an australian marine sponge dysidea dendyi
spongiapyridine: from an indonesian sponge of the genus spongia
spongiatriol: furanoditerpene from australian great barrier reef sponges of genus spongia; ; spongiatriol and epispongiatriol are isomers; rn refers to spongiatriol
spongidepsin: a 13-membered depsipeptide isolated from the vanuatu marine sponge spongia sp., has shown potent antitumor properties against a variety of nci tumor cell lines
spongin, Hymeniacidon sinapium: anti-inflammatory derived from hymeniacidon sinapium
spongistatin 1: a highly cytotoxic macrocyclic lactone polyether from a spongia species
spongistatin 6: a macrocyclic polyether lactone; isolated from spirastrella spinispirulifera
spoon protein, Drosophila: a dual-specificity a-kinase anchor protein essential for oogenesis; refseq nm_131993
sporamin A precursor, Ipomoea batatas: precursor of sporamin a; has 37 more amino acids than the mature protein; mw 24kda
sporamin A protein, Ipomoea batatas: storage protein of the tuberous roots of sweet potatoes deposited in the vacuole; mw 20kda; see also record for sporamin
sporamin protein, Ipomoea batatas: mixture of sporamin a & b; storage protein from tuberous roots of sweet potato; see also record for sporamin a
sporamycin: isolated from culture filtrate of streptopsorangium strain po-357
sporangiomycin: sulfur containing peptide from planomonospora parontospors; related to thiostrepton group of antibiotics
sporaricins: sporaricins a & b produced by saccharopolyspora hirsuta; structure; rn given refers to sporicin with unknown mf
sporaviridin: complex containing six components; structures given in first source; rn given refers to cpd with unknown mf; isolated from streptosporangium viridogriseum
spore coat proteins, Dictyostelium: proteins that form the outer layer of the encapsulated spore; amino acid sequence for sp96 given in first source
spore photoproduct lyase: a 40-kda bacterial polypeptide that shows regional amino acid sequence homology to dna photolyases; involved in repair of uv radiation-induced dna damage during spore germination
spore pigment, Streptomyces: from streptomyces halstedii; amino acid sequence given in first source; genbank lo5390
spore-specific proteins, Bacillus: see also records for spore coat proteins cote, cotg, cott and cotx; spoiiab is an anti-sigma factor; spoiie is a serine phosphatase
sporminarin A: antifungal metabolites from a fungicolous isolate of sporormiella minimoides
sporminarin B: antifungal metabolites from a fungicolous isolate of sporormiella minimoides
sporobacterin: a probiotic, based on bacillus subtilis 534, used to treat wounds
sporofusarin: produced by fusarium sporotrichella v. sporotrichioides; formed during spring thaw in grain wintering under snow
sporolact: a complex probiotic from lactobacteria & aerobic spore-forming bacteria; a russian compound; no other information available 2/96
sporolide A: halogenated macrolides from the marine actinomycete salinispora tropica; structures in first source
sporormielloside: from the endolichenic fungus sporormiella irregularis
sporostatin: inhibits cyclic adenosine 3',5'-monophosphate phosphodiesterase; from fermentation filtrate of sporormiella sp.
sporothric acid: from the fungus hypoxylon monticulosum, from a sphaerocladina sponge from the tahiti coast
sporozoite-surface protein 2, Plasmodium yoelli: amino acid sequence given in first source; a 140 kda protective plasmodium yoelii sporozoite antigen
sporulation-specific sigma factors: encoded by gene spoiigb; amino acid sequence given in first source
spoxazomicin A: produced by an endophytic actinomycete, streptosporangium oxazolinicum k07-0460
spoxazomicin B: produced by an endophytic actinomycete, streptosporangium oxazolinicum k07-0460
spoxazomicin C: produced by an endophytic actinomycete, streptosporangium oxazolinicum k07-0460
spoxazomicin D: from the appalachian coal fire-associated isolate streptomyces sp. rm-14-6
spp-1 protein, C elegans: isolated from caenorhabditis elegans; has antibacterial activity, suggesting that it may play a role in antibacterial mechanisms of c. elegans; amino acid ; genbank z29443
spray protein, Neurospora crassa: the protein is located in an organellar membrane, regulating the distribution of ca(2+) via calcineurin; amino acid
spri protein, Drosophila: sprint - sh2, poly-proline containing ras interactor; a drosophila homolog of rin1; genbank af312692 (sprint-a) and af312693 (sprint-b)
sprodiamide: a magnetic susceptibility-based mri contrast agent; a diagnostic aid; rn given refers to anhydrous compound
spruce pathogen-induced 2 peroxidase: from the roots of norway spruce; genbank aj250121; do not confuse with sp12 protein which is a salivary protein
spry4 protein, zebrafish: a feedback-induced antagonist of fgf signaling; genbank af371368
sptP protein, Salmonella typhimurium: a secreted protein tyrosine phosphatase with modular effector domains in the bacterial pathogen salmonella typhimurium; amino acid sequence known
spumigin A: thrombin inhibitor from the freshwater cyanobacterium anabaena compacta
spumigin J: thrombin inhibitor from the freshwater cyanobacterium anabaena compacta
spvB protein, Salmonella enterica virulence plasmid: from salmonella enterica virulence plasmid; amino acid
spz protein, Drosophila: a maternal effect protein with toll binding activity; required in the signal transduction pathway that establishes the dorsal-ventral pattern of the drosophila embryo; also act as an antifungal immune response in larvae and adults; amino acid sequence given in first source; refseq nm_079802
sqd protein, Drosophila: intitial organization of drosophila dorsoventral axis depends on the rna-binding protein encoded by the squid gene; aa sequence given in first source; refseq nm_169529
sqdA protein, Rhodobacter sphaeroides: amino acid sequence given in first source; 33.6 kda protein that complements a mutation deficient in accumulation of the sulfolipid sulfoquinovosyl diglyceride
sqdD protein, Rhodobacter sphaeroides: catalyzes the final step in the synthesis of nucleoside 5'-diphospho-sulfoquinovoses
squalene cyclase: nonoxidative conversion of squalene to tetrahymenol; does not go via 2,3-oxidosqualene
squalene epoxidase-cyclase: consists of squalene epoxidase (ec 1.14.99.7) plus 2,3-oxidosqualene lanosterol-cyclase (ec 5.4.99.7)
squalene-hopene cyclase: from bacillus acidocaldarius; cyclizes squalene into hopanoid triterpenes
squalestatin 1: ; inhibits both mammalian and fungal squalene synthetase; from fungus phoma sp (coelomycetes)
squalestatin 2: inhibits squalene synthase; from fungus phoma sp. (coelomycetes); rn refers to (5(2e,4s,6s),7s)-isomer
squalestatin 3: inhibits squalene synthase; from fungus phoma sp. (coelomycetes); rn refers to (7s)-isomer
squamocin: from seeds of annona squamosa; a trihydroxy-bis-tetrahydrofuran fatty acid lactone; inhibits e. coli nadh:quinone oxidoreductase (ndh-1)
squamosamide: natural compound from annoma squamosa; flz is the synthetic cyclic analog
squamostanin A: cytotoxic annonaceous acetogenin from the seeds of annona squamosa
squamostanin B: cytotoxic annonaceous acetogenin from the seeds of annona squamosa
squamous cell carcinoma-related antigen: useful marker for detecting, staging & for monitoring response to therapy in patients with squamous cell carcinoma of the lung; subfraction of tumor antigen ta-4; has been sequenced; genbank ab005548
squamulosone: from the plant, hyptis verticillata jacq. (labiatae)
squarroside C: a cycloartane 3,21-bisdesmoside from thalictrum squarrosum
sqv-5 protein, C elegans: a bifunctional glycosyltransferase that is probably localized to the golgi apparatus and is responsible for the biosynthesis of chondroitin but not heparan sulphate: genbank ay241925
sqv-7 protein, C elegans: a putative nucleotide sugar transporter that is involved in glycosaminoglycan biosynthesis; amino acid
sr protein, Drosophila: a drosophila muscle development gene product; an early growth response (egr) protein; amino acid sequence given in first source; refseq nm_079671
srP2 protein, S pombe: member of fission yeast essential for growth; amino acid  genbank af012278
srb protein, Bacillus subtilis: srb is a bacillus subtilis gene encoding a homolog of the alpha-subunit of the mammalian signal particle receptor; amino acid sequence given in first source; genbank d49781
src kinase associated phosphoprotein 2: 44% homologous to src kinase-associated phosphoprotein skap55
src-2 protein, C elegans: an src family kinase ortholog; refseq nm_061101.4
srlB protein, E coli: high-level expression negatively regulates gluconeogenesis
srlQ protein, E coli: a putative atp-binding proteins; found within the glucitol operon of e coli; amino acid sequence given in first source; homologous to kpsf protein
srp protein, Drosophila: ortholog of vertebrate gata factor; required for the morphogenesis of the endodermal gut, for hematopoiesis and fat body formation; amino acid sequence given in first source; refseq nm_169696
srw1 protein, S pombe: a negative regulator of cell cycle progression during g1 phase; homolog of hct1/cdh1 and related to fizzy; amino acid
ss protein, Drosophila: homologous to mammalian dioxin receptor; isolated from drosophila; amino acid ; refseq nm_057400
ssA-TIBF protein, Tetrahymena thermophila: a single-stranded dna-binding protein from tetrahymena; has been sequenced
ssSPTa: the isoforms share a conserved hydrophobic central domain and confer distinct acyl-coa substrate specificities
sseK3 protein, Salmonella typhimurium: genbank cbw18025
ssgA protein, bacterial: involvoed in sporulation of sterptomyces griseus; amino acid ; do not confuse with ssga protein which is a fungal protein
ssgB protein, Streptomyces coelicolor: related to the sporulation-specific cell division gene ssga; these genes, together with three others, constitute a new family of paralogous genes specific for streptomyces; has been sequenced
ssh protein, Drosophila: a family of phosphatases that have the property of f actin binding; amino acid
ssnA protein, E coli: involved in the decline of cell viability at the beginning of stationary phase in escherichia coli; related to chlorohydrolases and aminohydrolases; amino acid
ssp160 protein, silk: a lobe-specific silk protein; from chironomus thummi salivary glands; genbank u24265
sspB protein, E coli: binds to clpx and stimulates the atpase activity of this enzyme. in the presence of atpgammas; a specificity-enhancing factor for clpxp that controls substrate choice
sspJ protein, Salmonella: is found in the cytoplasmic membrane and periplasmic space; has been sequenced
ssrA protein, Salmonella typhimurium: genbank ae006468.2
sssAFP-2 protein, Myoxocephalus scorpius: skin-type antifreeze protein, encodes 92-residue mature polypeptides; amino acid ; genbank af305502
st protein, Drosophila: a member of the traffic atpase superfamily of transmembrane permeases; involved in transport of guanine and tryptophan as precursors of red and brown eye pigments; isolated from drosophila melanogaster; has been sequenced; refseq nm_079384
stN protein, Vibrio cholerae: amino acid sequence for nag-st given in febs lett 1985;193(2):250; a small peptide of 17 amino acid residues; belongs to the methanol-soluble, infant mouse-active class of stable toxin
sta protein, Drosophila: has 63% aa identity with human p40 protein; amino acid sequence given in first source; refseq nm_057402
stachybotrydial: a pancreatic cholesterol esterase inhibitor; also inhibits fucosyltransferase and sialyltransferase
stachybotrysin: an osteoclast differentiation inhibitor from the marine-derived fungus stachybotrys sp. kcb13f013
stachyonic acid A: derived from basilicum polystachyon; inhibitor of dengue virus
stachyrase A: a chymotrypsin-like serine proteinase from stachybotrys chartarum; amino acid
stachyssaponin A: terpene from stachys parviflora benth
stachyssaponin B: terpene from stachys parviflora benth
staggerer-specific protein SP 47: mw 47 kd; polypeptide from grossly underdeveloped cerebellum of neurological mouse mutant staggerer
stagonolide: nonenolide produced by stagonospora cirsii (fungi, ascomycota), a potential mycoherbicide of cirsium arvense (asteraceae)
stambomycin A: an antineoplastic antibiotic isolated from streptomyces ambofaciens
stambomycin B: an antineoplastic antibiotic isolated from streptomyces ambofaciens
stambomycin C: an antineoplastic antibiotic isolated from streptomyces ambofaciens
stambomycin D: an antineoplastic antibiotic isolated from streptomyces ambofaciens
staminol C: from orthosiphon stamineus of taiwan; has nitric oxide inhibitory activity
staminol D: from orthosiphon stamineus of taiwan; has nitric oxide inhibitory activity
stan protein, Drosophila: a seven-pass transmembrane cadherin that regulates planar cell polarity under the control of frizzled; a protocadherin; genbank ab028498
stannin: amino acid sequence given in first source; a 10 kda peptide expressed in trimethyltin-sensitive cells; may play a role in selective toxicity of organotin cpds; homologs have been identified in rabbit, human and drosophila; from rat brain
stanniocalcin 1 receptor, rat: the observed stc1 suppression of progesterone, but not estradiol, production further suggests the potential role of this paracrine hormone as a luteinization inhibitor
stansin 6: a resin glycoside with both neuroprotective and anticonvulsant activities; isolated from ipomoea stans
stap2b protein, zebrafish: refseq xm_021478235.1
staphage lysate: lysate of broth culture of two strains of coagulase positive staphylococcus aureus with polyvalent gratia bacteriophage; used in treatment of hidradenitis suppurativa
staphopain A protein, Staphylococcus aureus: has been sequenced
staphostatin A, Staphylococcus aureus: inhibits staphopain a; has been sequenced
staphostatin A, Staphylococcus epidermidis: highly specific, endogenous inhibitor of cysteine protease & a member of the staphostatin family
staphostatin B protein, Staphylococcus aureus: a proteinase inhibitor that inhibits staphopain b; isolated from staphylococcus aureus
staphylococcal delta toxin: rapidly disrupts cell membranes; has lymphocyte-activating effect
staphylococcal enterotoxin J: isolated from staphylococcus aureus; amino acid
staphylococcal exotoxin 1: isolated from staphylococcus aureus; has been sequenced; genbank af094826
staphylococcal nuclease R: an analog of micrococcal nuclease (staphylococcal nuclease a) in which a hexapeptide (dptvys) is attached to the n-terminal alanine of micrococcal nuclease
staphylococcal protein A-ricin A fusion protein, recombinant: recombinant plasmid containing functional fragment of staph protein a and ricin a chain; multiple n- and c- terminal fusions were prepared of ricin toxin a chain (rta) and staphylococcal protein a (pa)
staphylococcal pyrogenic exotoxin type B: from s. aureus; resembles closely streptococcal pe type b; mw approx 18 kda
staphyloferrin A: from staphylococcus hyicus dsm 20459; ; has siderophore activity
staphylokinase SFH: consists of staphylokinase and hirudin linked by fxa recognition peptide; an antithrombotic agent that lowers bleeding risk
staphylolysin: dry substance of endotoxin of staphylococcus haemolytic
staphylolytic protease: 33 kda periplasmic peptidase from pseudomonas aeruginosa with staphylolytic activity and protease activity on casein; includes both lasa and lasd enzymes
staphylopine: a broad-spectrum metallophore related to nicotianamine in staphylococcus aureus
staphylothrombin: enzyme resulting from the action of staphylocoagulase on prothrombin in stoichiometric process; thrombin is ec 3.4.21.5
staphyloxanthin: staph aureus pigment; glucose esterified with both a triterpenoid carotenoid carboxylic acid & a c15 fatty acid
starch deferoxamine: biocompatible high molecular weight iron chelators, increase binding capacity to iron and reduce toxicity
starch synthase III, Triticum aestivum: homologs from many plants; amino acid ; genbank af258608
starch-branching enzyme II: starch-branching enzyme from potato; genbank aj000004
starlicide: avian toxicant registered to control starlings at cattle and poultry feed lots; rn given refers to parent cpd
starvation lipoprotein, E coli: amino acid ; genbank l23625; do not confuse with slp protein, a blood protein
statolon: polyanionic polysaccharide from penicillium stoloniferum; induces interferon; used as antiviral agent & proposed as antineoplastic agent; minor descriptor (69-72); major descriptor (73-85); on-line search polysaccharides (69-85); index medicus search polysaccharides (69-72); statolon (73-85)
stau protein, Drosophila: required to localize maternal rnas in the drosophila egg; amino acid sequence given in first source
stau2 protein, mouse: dsrna-binding protein expressed in somatodendritic neurons; refseq nm_025303
staufen protein, mammalian: is an rna-binding protein that is associated with polysomes and localizes to the rough endoplasmic reticulum
staunoside D: ; isolated from stauntonia hexaphylla; stauntoside is also available
staunoside E: ; isolated from stauntonia hexaphylla; stauntoside is also available
stauntogenin-3-O-alpha-L-oleandropyranosyl-(1-4)-O-beta-D-digitoxopyranosyl-(1-4)-O-beta-D-oleandropyranoside: from cynanchum amplexicaule
stauntoside A: c21-steroidal glycoside from cynanchum stauntoi
stauntoside C1: bidesmoside triterpenoid saponin from stauntonia chinensis
staurolite: mineral with a cubic close packing of oxygen with al occupying octahedral interstices and si and fe occupying tetrahedral interstices; established structural formula h-fe2-al9-si4-o24
staurosporine aglycone: metabolite from culture broth of nocardiopsis sp.; a neurotrophin antag; inhibits bdnf trkb receptor
stavudine, lamivudine, nevirapine drug combination: generic fixed-dose combination of stavudine, lamivudine and nevirapine (gpo-vir) for treatment of advanced hiv infection
stc protein, Drosophila: involved in neuron development; refseq nm_057251
stck protein, Drosophila: a protein required for integrin-dependent cell adhesion and actin-membrane anchorage, is present at the leading edge of these migrating epithelia and is required for dc. by analysis of native protein complexes; refseq nm_079554
ste11 protein, S pombe: from schizosaccharomyces pombe; has hmg motif that is a critical regulator of sexual development; do not confuse with ste11 protein kinase from saccharomyces cerevisiae; amino acid sequence given in first source
stearamide dihydroxyisobutylamine-stearate: structure may be tentative
stearamidoethyl diethylamine: a cationic surfactant; an emulsifier used in topical medications and cosmetics
stearated-Ht31 peptide: inhibits interaction between akap and rii subunits of pka
stearic acid 4-((n-pentoxy)phenethyl) ester: an anti-infective agent isolated from stemodia foliosa
stearidonic acid: rn given refers to cpd with unknown mf; 18:4 n-3 fatty acid
stearoyl ACP desaturase, Arabidopsis: a fatty acid desaturase modulates the activation of defense signaling pathways in plants; amino acid
stearoyl alpha-lysolecithin: rn given refers to cpd without isomeric designation
stearoyl transacylase: from bovine testis membranes; coa dependent; transfers stearoyl groups from a variety of phospholipids to sn-2-arachidonoyl lysophosphatidic acid
stearoyl-sulfogalactosylsphingosine: substrate for cerebroside sulfatase assay
stearoylvelutinal: converted to the hot-tasting velleral by saliva
stearyl-(D)-K6L9 peptide: a synthetic peptide based on (d)-k6l9 peptide
stearyl-Nle(17)-neurotensin(6-11)VIP(7-28): a lipophilic vasoactive intestinal peptide analog enhances the antiproliferative effect of chemotherapeutic agents on cancer cell lines
stearyl-norleucine(17)-vasoactive intestinal peptide: may be useful for the treatment of male impotence
stearyltrimethylammonium: cationic detergent; rn given refers to parent cpd
steatite: a ceramic material with a vickers hardness similar to that of enamel; contains 65% silica, 29% magnesium oxide and trace amounts of titanium, ferric, calcium, potassium & sodium oxides; rn refers to steatite mg(sio3)
stecrisp protein, Trimeresurus stejnegeri: a cysteine-rich secretory protein; amino acid sequence in first osurce
stefin D protein, Sus scrofa: rn refers to stefin d1; amino acid
steganacin: bisbenzocyclooctadiene lactone extract from steganotaenia araliacea
steganangin: bisbenzocyclooctadiene lactone extract from steganotaenia avaliacea
stegane: oxidation of stegane yields the antineoplastic agent steganacin
stejnefibrase 1: a fibrinogenolytic enzyme from chinese green tree viper, trimeresurus stejnegeri venom; mw 50 kda
stejnefibrase 2: a fibrinogenolytic enzyme from chinese green tree viper, trimeresurus stejnegeri venom; mw 31 kda
stejnefibrase 3: fibrinogenolytic enzyme from chinese green tree viper, trimeresurus stejnegeri venom; mw 32 kda
stejnin protein, Trimeresurus stejnegeri: isolated from chinese green tree viper; precursor amino acid sequence in first sourrce
stejnobin: a fibrinogen-clotting enzyme from trimeresurus stejnegeri venom; a single chain glycoprotein of mw 44 kda; n-terminal amino acid
stejnulxin protein, Trimeresurus stejnegeri: a platelet agonist; amino acid
stelleralide A: potent anti-hiv daphnane-type diterpenoid from stellera chamaejasme l
stelleralide B: potent anti-hiv daphnane-type diterpenoid from stellera chamaejasme l
stelleralide C: potent anti-hiv daphnane-type diterpenoid from stellera chamaejasme l
stelleralide G: anti-hiv daphnane-type diterpenoid from stellera chamaejasme
stellerasme A: antineoplastic from the aerial part of stelleropsis tianschanica
stellettamide C: antibacterial alkaloid from a marine sponge stelletta sp.
stellettazole B: antibacterial alkaloid from a marine sponge stelletta sp.
stellettazole C: antibacterial alkaloid from a marine sponge stelletta sp.
stellettin A: an isomalabaricane triterpenoid; isolated from the sponge stelletta tenuis
stellettin L: cytotoxic triterpene from the marine sponge stelletta tenuis
stellettin M: cytotoxic triterpene from the marine sponge stelletta tenuis
stellettoside A1: cytotoxic glycosylated fatty acid amide from a stelletta sp.
stellettoside A2: cytotoxic glycosylated fatty acid amide from a stelletta sp.
stelliferin riboside: from the fijian sponge geodia globostellifera
stem cell inhibitory factor: produced by thymus cells, following treatment with antilymphocyte serum; inhibits colony formation by bone marrow cells; possesses no antiviral activity
stemar-13-ene synthase: catalyzes the cyclization of syn-copalyl diphosphate to yield stemar-13-ene
stemmadenine: from seeds of tabernaemotana dichotoma; also rauwolfia and rhazya; ; rn given refers to (19e)-isomer
stemoburkilline: dihydrostemofoline alkaloid from a root extract of stemona burkillii prain
stemocurtisinol: pentacyclic stemona alkaloid with a pyrido[1,2-a]azepine a,b-ring system
stemodene synthase, Oryza sativa: catalyzes conversion of syn-copalyl diphosphate to stemod-13(17)-ene
stemodin: ; isolated from stemodia maritima; a major stemodane diterpene; rn given for (2alpha,5alpha,9beta,13alpha,17beta)-isomer
stemodinone: rn given for (4as-(4aalpha,6abeta,8alpha,9alpha,11aalpha,11bbeta))-isomer
stemofoline: rn given for (2s-(2alpha,3beta,4beta,5alpha,5abeta,6beta,8abeta,9s*))-isomer
stemonone A: polyketide isolated from roots of stemona tuberosa; has anti-inflammatory properties
stemonone B: polyketide isolated from roots of stemona tuberosa; has anti-inflammatory properties
stemphylanthranol A: from the endophytic fungus stemphylium globuliferum
stemphylanthranol B: from the endophytic fungus stemphylium globuliferum
stemucronatoside K: an immunosuppressive agent isolated from stephanotis mucronata
stemucronatoside L: from the roots of stephanotis mucronata, inhibits th1/th2 immune responses in vitro
stenbolone: ; rn given from merck; rn given refers to the (5alpha,17beta)-isomer; rn for cpd without isomeric designation not available 7/91
stenbolone acetate: rn given from merck; rn given refers to the (5alpha,17beta)-isomer; rn for cpd without isomeric designation not available 7/91
stenodactylin protein, Adenia stenodactyla: type 2 ribosome-inactivating protein, highly toxic to glial and neuronal cells
stenoparib: poly(adp-ribose) polymerase (parp) inhibitor
stenophylline B: rn given from toxline; rn not in chemline 12/84
stenopril: rn given refers to parent cpd; stenopril refers to the hcl
stenoxobin protein, Lachesis muta stenophyrs: thrombin-like enzyme from bushmaster venom; a glycoprotein containing 1.6 mole n-acetylneuraminic acid per mole protein; different from other thrombin-like enzymes from snake venoms that only release fibrinopeptide a; also releases fibrinopeptide b; mw 37,000; aa composition in first source
stenusin: secretion from collecting bladders of beetles of genus stenus comma; rn is from 9th ci
stephalagine: aporphine alkaloid from annona crassiflora fruit peel
stephanine: has high affinity for serotonin receptors; rn given refers to (r)-isomer; a precursor to aristolochic acids
stephanotic acid methyl ester: methyl ester of the naturally occurring macrocyclic pentapeptide stephanotic acid containing an unusual beta-substituted alpha-amino acid with a tryptophan c-6 to leucine beta-carbon link
stephanthraniline A: aglycone of stephanoside e; has immunosuppressive activity; isolated from stephanotis mucronata
stephenanthrine: from the root of stephania tetranda s. moore & dennettia tripetala
stercobilin: rn given refers to (2r,3r,4s,16s,17r,18r)-isomer
stereocalpin A: antitumor depsipeptide from the dry lichen ramalina terebrata of antarctica
sterequinone F: from stereospermum personatum with antioxidant and xanthine oxidase inhibitory potential
sterequinone G: from stereospermum personatum with antioxidant and xanthine oxidase inhibitory potential
sterequinone H: from stereospermum personatum with antioxidant and xanthine oxidase inhibitory potential
sterequinone I: from stereospermum personatum with antioxidant and xanthine oxidase inhibitory potential
stereumin T: antibacterial from the culture of stereum cf. sanguinolentum bcc 22926
sterhirsutin A: antineoplastic from fthe culture of stereum hirsutum collected in tibet plateau
sterhirsutin B: antineoplastic from fthe culture of stereum hirsutum collected in tibet plateau
sterile 20-like protein kinase nerve injury-associated kinase: an upstream activator of the jnk pathway; amino acid ; do not confuse with nak protein
sterlane: contains lauryloxypropylaminobutyric acid, dodecylaminopropylaminobutyric acid, & benzalkonium chloride
steroid (23R)-hydroxylase: increased (23r)-hydroxylase activity in patients with cerebrotendinous xanthomatosis, an inborn error of metabolism in bile acid synthesis resulting in (23r)-hydroxylation of bile acids
steroid 11-alpha-hydroxylase: enzyme that catalyzes 11-alpha-hydroxylation of steroids
steroid 14-alpha-hydroxylase: from induced vegetative cell cultures of mucor piriformis; hydroxylates progesterone to 14alpha-hydroxyprogesterone in the presence of nadph & oxygen
steroid 15-alpha-hydroxylase: a heme-thiolate enzyme (cytochrome p-450) that catalyzes 15-alpha hydroxylation of testosterone, androstenedione, and progesterone
steroid 15-beta-hydroxylase: cytochrome p-450 enzyme that catalyzes 15-beta-hydroxylation of steroids; refseq nm_031572 (rat)
steroid 16-beta-hydroxylase: cytochrome p-450 enzyme that catalyzes 16-beta-hydroxylation of testosterone, androstenedione, or estrone; include several members of the p-450 2b subfamily
steroid 19-hydroxylase: enzyme from adrenal mitochondria; forms 19-hydroxy-11-deoxycorticosterone
steroid 9-alpha-hydroxylase: consists of an electron transport chain of nadh-dependent flavoprotein reductase & 2 iron-sulfur proteins; from nocardia
steroid N-acetylglucosaminyltransferase: substrate steroids may be replaced by specific cpds
steroid alpha-ketol oxidase: in conjunction with corticosteroid side-chain-isomerase (ec 5.3.1.21) converts desoxycorticosterone to a 20-oxo-21-oic acid (pregnenoic acid)
steroid hormone 7-alpha-hydroxylase: a microsomal enzyme highly active in 7-alpha-hydroxylation of testosterone, androtenedione, progesterone, and a variety of structurally unrelated compounds including fatty acids and xenobiotics; encoded by genes in the cyp2a subfamily
steroid receptor RNA activator: exists in distinct ribonucleoprotein complexes, one of which contains the nuclear receptor coactivator steroid receptor coactivator 1; cell. 1999 apr 2;97(1):17-27
steroid receptor RNA activator, human: modulates transcriptional activity of steroid receptors; genbank af293024
steroid sulfotransferase: catalyzes the reaction of 3'-phosphoadenylyl sulfate and a phenolic steroid to form adenosine 3',5'-bisphosphate and steroid o-sulfate; has broad specificity
sterol 3-beta-glucosyltransferase: a plasma membrane-bound enzyme that catalyzes the glucosylation of plant sterols; reaction: sterol + udp-glucose = steryl-3-beta-glucoside + udp
sterol O-acyltransferase 1: catalyzes reaction acyl-coa + cholesterol <=> coa + cholesterol ester, don't confuse with acetyl-coa c-acetyltransferase 1 which is also referred to as acat1
sterol carrier proteins: refseq nm_011327 (mouse); nm_002979 (human)
sterol delta-5 desaturase: involved in ergosterol synthesis; do not confuse with delta5,7-sterol delta-7-reductase which is involved in cholesterol biosynthesis
sterolglucoside synthase: involved in formation of sterolglucoside in saccharomyces cerevisiae from udpglucose; specific structure of product not given; consider also ec 2.4.1.173, sterol 3beta-glucosyltransferase
stesakine-9-O-glucopyranoside: isolated from the seeds of stephania cepharantha
stetterlysin: highly thermostable subtilisin-like serine proteinase from the archaeon, thermococcus stetteri; amino acid sequence of catalytic domain given in first source; genbank af015225
stevastelin B: a depsipeptide containing three amino acids and 3,5-dihydroxy-2,4-dimethylstearic acid from penicillium
steviol: aglucon of stevioside; rn given refers to (4alpha)-isomer
steviol 19-O-beta-D-glucopyranosiduronic acid: from steviol
stevioside: kaurene glucoside from leaves of stevia rebaudiana; 300 times as sweet as sugar
stewartianol: a melanogenesis inhibitor; isolated from stewartia pseudocamellia
stewartianol-3-O-glucoside: a melanogenesis inhibitor; isolated from stewartia pseudocamellia
stewartiiside: alpha-glucosidase inhibitor from phlomis stewartii
stg protein, Drosophila: functions as a dosage-dependent inducer in mitotic control; it is a tyrosine protein phosphatase required for progression of the cell cycle; it may directly dephosphorylate p34(cdc2) and activate the p34(cdc2) kinase activity; homologous to cdc25 protein; regulator of mitotic initiation by activating cdc2 kinase
sticholysin II: from the sea anemone stichodactyla helianthus; amino acid ; genbank aj005038
stichoposide: triterpene glycoside; rn given refers to stichoposide a
stigmalactam: from the extracts of fissistigma balansae and fissistigma oldhamii
stigmast-5-en-3beta-ol-3-O-beta-D-(2'-n-triacontanoyl)glucopyranoside: from the fruits of lycium chinense
stigmast-5-en-3beta-ol-3beta-dodecanoate: from the flowers of punica granatum linn
stigmast-5-en-3beta-ol-3beta-tetradecanoate: from the flowers of punica granatum linn
stigmasta-24(28)-en-3,6-dione: has antineoplastic activity; isolated from tydemania expeditionis
stigmasta-3,5-dien-7-one: has anti-inflammatory activity; isolated from phragmitis rhizoma
stigmasta-7,22,25-triene-3-O-(6'-palmitoyl)glucopyranoside: isolated from bulbs of bolbostemma paniculatum
stigmastanol: saturated analog of beta-sitosterol; rn given refers to (3beta,5alpha)-isomer
stigmasterol 3-O-beta-D-glucopyranoside: an antioxidant from monochoria vaginalis
stigmasterol glucoside: toxic component of cycas circinalis seeds possibly etiologic in guamanian als-parkinsonism-dementia complex
stigmasteryl 3-O-glucoside 6'-O-palmitate: from blutaparon portulacoides (amaranthaceae)
stigonemapeptin: from the bloom-forming freshwater cyanobacterium stigonema sp. with elastase inhibitory activity
stilbazium iodide: parent cpd not in chemline 9/17/82
stilbene oxide: inducer of epoxide hydratase; rn given refers to cpd without isomeric designation
stilbene oxide hydrolase: aspect of epoxide hydrolase, ec 3.3.2.3
stilbene synthase: extract from pine seedlings catalyzed the conversion of cinnamoyl-coa & malonyl-coa into 3,5-dihydroxystilbene
stilbostat: carbamidic deriv of tetrakis(2-chloroethyl)-stilbestrol
stilbostemin B 3'-beta-D-glucopyranoside: bibenzyl glycoside from the roots of stemona tuberosa
stilbostemin H 3'-beta-D-glucopyranoside: bibenzyl glycoside from the roots of stemona tuberosa
stilbostemin I 2''-beta-D-glucopyranoside: bibenzyl glycoside from the roots of stemona tuberosa
stimulin, bacterial: metabolic product of staph aureus used in shortening time of fracture healing; do not confuse with synonym to nikethamide
stimuliv: indigenous compound containing 60mg andrographis paniculata (kalmegh), 60mg eclipta alba (bhringaraj), 60mg peumus boldus molina (boldo), 100 mg cynara scolymus l. (artichoke) &100 mg fumaria periflora(pittapapada; used against hepatotoxicity of antitubercular drugs
stinging nettle lectin: mw 8-9kda; found only in rhizome of above plant; agglutinates erythrocytes nonspecifically irrespective of blood group type & induces the production of gamma-interferon in human lymphocytes
stiptatonic acid: rn is from 9th ci; cpd not in chemline 9/17/82
stizolicin: sesquiterpene lactone germacranolide from stizolophus balsamitus (asteraceae); rn given for (1ar-(1ar*,4z,7r*(e),7as*,10ar*,10bs*))-isomer
stj protein, Drosophila: a voltage-gated calcium channel; refseq nm_137058
stkA protein, Dictyostelium discoideum: appears to be involved in directing cells toward becoming spores or stalk cells; isolated from dictyostelium discoideum; amino acid ; genbank u68754
stm protein, zebrafish: appears to be involved in controlling shape of otoliths; amino acid ; refseq nm_198817
stmA protein, Drosophila: an integral plasma membrane lipase involved in phototransduction; refseq nm_165625
stnA protein, Drosophila: binds synaptotagmin; refseq nm_001042851
stnB protein, Drosophila: binds synaptotagmin; refseq nm_001042854
stoichactin: antitumor agent purified from tahitian sea anemone (coelenterate) stoichactus kenti
stolonic acid A: cytotoxic cyclic peroxides from an indian ocean ascidian stolonica species
stolonic acid B: cytotoxic cyclic peroxides from an indian ocean ascidian stolonica species
stolonidiol: rn given for (1as-(1ar*,6ar*,9r*,10as*,11ar*))-isomer; isolated from the japanese soft coral, clavularia
stoloniferone 5: a bioactive steroid from the okinawan soft coral, clavularia viridis
stoloniferone 6: a bioactive marine steroid from the okinawan soft coral, clavularia viridis
stolonilactone: a terpenoid-related compound, isolated from the okinawan soft coral clavularia koellikeri
stolonine A: has antineoplastic activity; isolated from the tunicate cnemidocarpa stolonifera
stolonine C: has antineoplastic activity; isolated from the tunicate cnemidocarpa stolonifera
stolonoxide E: cytotoxic metabolite from the marine ascidian stolonica socialis
stolonoxide F: cytotoxic metabolite from the marine ascidian stolonica socialis
stomadhesive: protects while allowing normal healing underneath; used in pressure sores, excoriated skin surrounding ileostomy
stonustoxin: mw 148000 protein composed of two subunits with respective mw of 71000 and 79000; amino acid sequence of beta subunit given in first source; isolated from synanceja horrida
storage granule protein 23: 23-kda protein utilized in regulated secretory pathway; amino acid ; genbank u64446
storage protein deamidase: deamidates glutaminyl residues; isolated from germinating wheat grains
storage protein receptor, Saecophaga: mw 120,000 membrane protein of pupal fat body in sarcophaga peregrina
storage proteins, Insecta: synthesized in fat body during larval feeding stage & secreted into hemolymph; with puparium formation they are selectively taken up again by fat body; used as source of amino acids & energy for synthesis of new proteins during metamorphosis
stp protein, Bacteriophage T4: activates prrc ribonuclease (anticodon nuclease); isolated from bacteriophage t4; has been sequenced; do not confuse with stp-c488 protein
stpC protein, Staphylococcus aureus: a potential atp-binding casette (abc) transporter; amino acid sequences of stpa and stpc given in first source; see also record for stpa protein (from e. coli)
strand exchange protein, Vaccinia virus: mw 110 kd; has been sequenced
strefuranone A: from streptomyces sp. hs-nf-853
strepfen: preparation used for continuous treatment for pharyngeal pain and is produced as dissolving tablets, active component is flurbiprofen (8.75 mg) , nsaid
strepsesquitriol: from the deep-sea-derived actinomycete streptomyces sp. scsio 10355
streptavidin-binding peptide: a streptavidin-binding peptide, used for both the one-step purification and the detection of recombinant proteins; peptide
streptavidin-transforming growth factor-alpha protein, recombinant: a recombinant plasmid containing the coding regions for streptavidin core and mature human transforming growth factor-alpha; st-tgf-alpha serves as a high-modular "molecular bridge" for the passage of a wide variety of effector molecules into target cells
streptavidin-tricolor: a reliable marker for nonviable cells subjected to permeabilization or fixation
streptazone E: alkaloid from streptomyces sp. neau-z4
streptazone F: alkaloid from streptomyces sp. neau-z4
streptidine: component of streptomycin molecule; rn given refers to parent cpd
streptin: a class ai bacteriocin; isolated from streptomyces pyrogenes; genbank ab030831
streptobactin: from marine-derived streptomyces sp. ym5-799
streptobicillin depot: combination of benzathine penicillin, streptomycin sulfate & vitamin a oleosum in suitable base for treating mastitis in cows
streptocarbazole A: indolocarbazole from the marine-derived actinomycete strain streptomyces sp. fma
streptocarbazole B: indolocarbazole from the marine-derived actinomycete strain streptomyces sp. fma
streptochlorin: inhibits both nf-kappab activation and angiogenesis; isolated from marine streptomyces
streptocidin A: a cyclic decapeptide antibiotic produced by streptomyces sp. tu6071
streptocidin B: a cyclic decapeptide antibiotic produced by streptomyces sp. tu6071
streptocidin C: a cyclic decapeptide antibiotic produced by streptomyces sp. tu6071
streptocidin D: a cyclic decapeptide antibiotic produced by streptomyces sp. tu6071
streptocin: bacteriocin isolated from cultures of streptococcus pyogenes strain ff22; rn is from 9th ci, chem subs index
streptocinnamides: seven amino acid residues depsipeptides with highly chlorinated isolated from streptomyces sp. kmm 9044
streptococcal M protein: type-specific protein on surface of group a streptococci antigens; iggfc-& albumin-binding streptococcal surface protein
streptococcal M protein receptor: sialic acid-containing receptor for m protein; has been sequenced
streptococcal beta antigen: from c protein complex of group b streptococci; binds iga; amino acid sequence given in first source
streptococcal group A mitogen: extracellular product of group a streptococci nonspecifically mitogenic for both b & t lymphocytes; may be same as erythrogenic toxin (see related record)
streptococcal group B hemolysin: from steptococcus agalactiae; amino acid sequence given in first source
streptococcal nuclease: from streptococcus hemolyticus; degrades rna & dna producing oligonucleotides terminating in 5'-phosphate
streptococcal polysaccharide type II-tetanus toxoid conjugate vaccine: group b streptococcal (gbs) type ii polysaccharide covalently linked to tetanus toxoid
streptococcal polysaccharide-tetanus toxoid conjugate vaccine: group b streptococcal (gbs) type v polysaccharide covalently linked to tetanus toxoid
streptococcal protective antigen: a 24 kda antigen; genbank af086813
streptococcal surface enolase: 45-kda plasmin(ogen) binding protein from group a streptococci; an alpha-enolase; n-terminal 50 amino acid
streptococcin A M49 protein, Streptococcus: produced by certain strains of m-type 49 group a streptococci; amino acid sequence given in first source; genbank l36235
streptocollin: type iv lanthipeptide produced by streptomyces collinus tü 365
streptogramin A acetyltransferase, Enterococcus faecium: amino acid sequence given in first source
streptogramin B lyase: an intramolecular lyase similar to ec 5.5.1.1; involved in resistance to etamycin and vernamycin b(alpha) in streptomyces lividans; reaction given in first source
streptogrisin A: before 1992 included in the group of microbial serine proteinases ec 3.4.21.14
streptogrisin B: before 1992 included in the group of microbial serine proteinases ec 3.4.21.14
streptokordin: has antineoplastic activity; isolated from a marine streptomyces species
streptolidine: rn given refers to (4s-(4alpha,5beta(s*)))-isomer
streptolydigin: antibiotic isolated from culture filtrates of streptomyces lydicus; active against gram-postive bacteria except micrococci; minor descriptor (75-87); on line & index medicus search antibiotics (75-87)
streptolysin S: oxygen-stable hemolysin produced by the group a streptococus upon exposure to various substances;
streptolysin S precursor: group a streptoccus cellular potential hemolysin precursor to extracellular streptolysin s
streptomonomicin peptide, Streptomonospora alba: a lasso peptide antibiotic
streptomycin 3''-adenylyltransferase: mediates bacterial resistance to the antibiotics streptomycin and spectomycin
streptomycin 3''-kinase: phosphorylates the 3'' oh group on the amino sugar of streptomycin
streptomycin 6-kinase: datp can replace atp; dihydrostreptomycin, streptidine & 2-deoxystreptidine can act as acceptors
streptomycin-6-phosphatase: final step in streptomycin biosynthesis; dihydrostreptomycin-6-p is hydrolyzed to dihydrostreptomycin
streptomycin-spectinomycin adenylyltransferase: for radioenzymatic assay of spectinomycin
streptomycylamine: rn given refers to d-streptamine-l-glucose-l-lyxose-isomer
streptophenazine A: from the marine streptomyces sp. strain hb202
streptophenazine G: isolated from cultures of marine streptomyces sp. strain hb202
streptoseolactone: from marine-derived actinomycete streptomyces seoulensis
streptothricin E: see also streptothricin f for racemomycin a: 3808-42-2, racemomycins: 11006-72-7, yazumycin: 11051-45-9
streptothricin F: streptothricin group of antibiotics; see also racemomycins: 11006-72-7, streptothricin e for racemomycin c: 3776-38-3, yazumycin: 11051-45-9
streptothricin acetyltransferase: confers resistance to streptothricin in gram-negative bacteria; site of acetylation not specified 4/85
streptourosol: combination aerosol preparation containing trimecaine, methyluracil, & streptocide
streptoverticillin: antifungal alkaloid produced by streptoverticillium morookaense
streptoverticillinone: antifungal alkaloid produced by streptoverticillium morookaense
streptovirudin: new antibiotics with antiviral activity isolated from streptomyces grisoflavus; rn given refers to cpd with unspecified mf
stresgenin B: inhibits heat-induced heat shock protein gene expression; isolated from streptomyces
stress protein, 66-kDa (Physarum): associated with cyst formation, homolog of yeast aip1; amino acid ; genbank u86011
stress-inducible protein 1, Leishmania major: lmsti1 isolated from leishmania major; amino acid
strevertene A: produced by streptomyces psammoticus, effective against tomato fusarium wilt
strevertene B: produced by streptomyces psammoticus, effective against tomato fusarium wilt
striated fiber assemblin: a major structural protein of the system i fibers, associated with flagellar microtubules in green algae; mw about 34 kda; amino acid sequence known; do not confuse with assemblin, a viral protease
striatoxin protein, Conus striatus: cardiotonic glycoprotein from venom of marine snail conus striatus
strictosidine: rn given refers to (2s-(2alpha,3beta,4beta(r*)))-isomer; formed by mannich reaction of tryptamine with secologanin; a precursor to ajmalicine and stemmadenine and other indole alkaloids
strictosidine glucosidase: enzyme for deglycosylation of strictosidine; amino acid