NLK-NML/MeSH-CZ-2025-notes huggingface dataset:
amorphin flavonoid: hepatoprotective flavonoid from amorpha fructiosa; rn given refers to (2r-(2alpha,6aalpha,12aalpha))-isomer; ; amorphin protein (nm) is also available
amorphous calcium phosphate: composed of complexes of non-crystalline calcium phosphate with stochiometry of 1.5; it serves as a precursor for hydroxyapatite and may represent 8-10% of bone mineral
amoxicillin, ascorbic acid, niacinamide, riboflavin, thiamine drug combination: bulgarian drug
ampelomin A: from a terrestrial ampelomyces fungus; exhibited weak activity against alpha-glucosidase
ampelomin E: polyoxygenated methyl cyclohexanoid from ampelomyces fungus
ampelopsin: hepatoprotective agent; isolated from hovenia dulcis; rn given for (2r-trans)-isomer
amphenone B: was mh 1975-92 (see under butanones 1975-90); use butanones to search amphenone b 1975-92
amphetaminil: a supposedly insoluble amphetamine complex that may release amphetamine; proposed as central nervous system stimulant; minor desriptor (78-86); on line & index medicus search amphetamines (75-86); rn given refers to parent compound
amphiCdx protein, Branchiostoma floridae: amino acid ; genbank af052465
amphiGsx protein, Branchiostoma floridae: amino acid sequence given in first source; genbank af052463
amphiXlox protein, Branchiostoma floridae: amino acid ; genbank af052464
amphidinin B: a polyketide metabolite, amphidinin b , has been isolated from a marine dinoflagellate amphidinium sp.
amphidinol 18: from the marine dinoflagellate amphidinium carterae
amphidinol 19: 7-sulfate derivative of amphidinol 18 from the marine dinoflagellate amphidinium carterae
amphidinol 22: from the marine dinoflagellate amphidinium carterae
amphidinolide B6: cytotoxic macrolide from a symbiotic dinoflagellate amphidinium species
amphidinolide B7: cytotoxic macrolide from a symbiotic dinoflagellate amphidinium species
amphidinolide C: a potent cytotoxic 25-membered macrolide from marine dinoflagellate amphidinium sp.
amphidinolide D: a cytotoxic macrolide from amphidinium; rn (from ca index guide 1989) refers to amphidinolide b (epimer of amphidinolide d)
amphidinolide F: cytotoxic macrolide from the marine dinoflagellate amphidinium sp
amphidinolide N: cytotoxic; from the marine microorganism amphidinium sp.; stucture in first source
amphidinolide Q: a cytotoxic 12-membered macrolide isolated from a marine dinoflagellate amphidinium sp.
amphidinolide T2: cytotoxic; from symbiotic marine dinoflagellate amphidinium sp.
amphidinolide W: a 12-membered macrolide from dinoflagellate amphidinium sp.
amphidinolide X: 16-membered macrolide from dinoflagellate amphidinium sp.
amphilectosin A: from the organic extract of pseudopterogorgia elisabethae
amphilectosin B: from the organic extract of pseudopterogorgia elisabethae
amphinase, Rana pipiens: a cytotoxic ribonuclease from rana pipiens oocytes; amino acid
amphinetrin: expressed in midline structures during embryonic and larval development; amino acid ; genbank aj252166
amphiphysin: amino acid sequence given in first source; a 75 kda acidic protein, associated with synaptic vesicles; from mammalian brain; amphiphysin i & ii are isoforms
amphirionin-2: has antineoplastic activity; isolated from the dinoflagellate amphidinium
amphirionin-4: from cultivated algal cells of the marine dinoflagellate amphidinium species; has potent proliferation-promoting activity
amphisin: cyclic lipoundecapeptide, from pseudomonas sp. strain dss73
amphodyn: horse chestnut extract & hydroxyphenylethylamino-ethanol; improves venous circulation
amplexicine: an antioxidant flavan-3-ol from polygonum amplexicaule
amplexicogenin B-3-O-beta-D-cymaropyranoside: from cynanchum amplexicaule
amplexicogenin--3-O-beta-D-cymaropyranosyl-(1-4)-alpha-L-cymaropyranosyl-(1-4)-beta-D-cymaropyranoside: from cynanchum amplexicaule
ampreloxetine: a reuptake inhibitor of both serotonin and norepinephrine
ampullicin: ampullicin and (+)-isoampullicin are two fungal metabolites with growth regulatory activity isolated from ampulliferina sp.
ampullosporin: a 15-membered peptaibol-type antibiotic from sepedonium ampullosporum
amrubicinol: a diastereoisomeric mixture; a synthetic antracycline drug
amsacrine-DNA: complex has the same toxicity & therapeutic effect as amsacrine
amthamine: histamine h2 receptor agonist; structure & rn given in first source; rn given refers to parent cpd
amtizol: used for recovery of consciousness after ketamine anesthesia; antihypoxic; a ketamine antagonist
amurenamide A: has antineoplastic activity; isolated from phellodendri amurense
amurensisin: a catechin type procyanidin found in seeds of vitis amurensis
amurensoside A: steroid glycoside from the starfish asterias rathbuni
amurin-3 protein, Rana amurensis: a component of lin wa pi, used as a topical antimicrobial wound dressing; amino acid
amuvatinib: c-kit/axl tyrosine kinase inhibitor that synergizes with docetaxel (taxotere) and is cytotoxic to gastrointestinal stromal tumor cells
amyR protein, Aspergillus: a transcriptional activator gene, involved in the amylolytic gene expression in aspergillus oryzae; genbank ab012945
amycenone: has antidepressant and ant-inflammatory activities; an extract of hericium erinaceum
amycomycin A: isolated from an actinobacterium amycolatopsis sp.
amycomycin B: isolated from an actinobacterium amycolatopsis sp.
amygdalin beta(1-6)glucosidase: forms prunasin & glucose
amyl-1-18 octadecapeptide: a translation inhibitor derived from rice alpha-amylase
amylase A 180: secreted by a alkaliphilic organism; consists of single type of polypeptide chain mw 186.5 kda & hydrolyzes starch by exo-attack releasing malto-pentaose as preferential product; exhibits both the sequence characteristics of alpha & beta amylase
amylase, phosphates, proteases drug combinations: russian preparation with thrombolytic properties; contains proteases, phosphates, & amylase; from cultures of asp. terricola
amylase-dextran conjugate: protects amylase against heat, proteolytic enzymes & denaturing agents
amylin (20-29): a key determinant of amyloid formation in human type ii diabetes; has been sequenced
amylin (8-37): enhances insulin action and alters lipid metabolism in normal and insulin-resistant rats
amylin(1-8): a cyclic peptide consisting of the eight n-terminal amino acids of the 37-amino acid peptide amylin; induces proliferation of primary osteoblasts and bone formation in healthy male mice
amylin-biotin: useful ligand for the study of amylin-cgrp receptor expression; facilitates the isolation of amylin and/or cgrp receptor complexes
amylinamide: has calcitonin-like effects; rat islet amyloid polypeptide with cooh-terminal amide
amylo-1,6-glucosidase: catalyzes endohydrolysis of 1,6-alpha-d-glucoside linkages at points of branching in chains of 1,4-linked alpha-d-glucose residues
amylogenin protein, Zea mays: a self-glucosylating protein from sweet corn; has been sequenced
amyloglucan: produced from starch by streptococcus sanguis; insoluble glucan molecule
amyloid A-degrading serine protease: reduced in amyloidosis associated with rheumatoid arthritis
amyloid AGel protein, human: gelsolin-derived fragment of the finnish type; has been sequenced
amyloid beta-peptide (39-42): inhibits neurotoxicity of abeta42
amyloid beta-protein (1-17): a major amyloid-β fragment isoform in cerebrospinal fluid and blood with possible diagnostic value in alzheimer's disease
amyloid beta-protein (1-28): binding of synthetic beta-amyloid peptide fragments to glycosaminoglycan is ph-dependent
amyloid beta-protein (1-38): amino acid sequence given in first source; neurotoxic to rat brain
amyloid beta-protein (1-40): although acutely neurotoxic in both rat & monkey cerebral cortex, neuronal degeneration in primates resembles more closely to that found in alzheimer's disease; amino acid sequence has been determined
amyloid beta-protein (1-42): stimulates glial cell in vitro to produce growth factors that accumulate in senile plaques in alzheimer's disease
amyloid beta-protein (10-35): retains the ability to add to alzheimer's plaques, in contrast to other truncated peptides; has been sequenced
amyloid beta-protein (12-28): impairs memory retention in mice; amino acid sequence given in first source
amyloid beta-protein (13-17): binding of synthetic beta-amyloid peptide fragments to glycosaminoglycans is ph-dependent
amyloid beta-protein (16-20): the self-assembly is critical in amyloid fibrillization
amyloid beta-protein (16-22): one of the shortest fibril-forming fragments of alzheimer's full-length beta-amyloid peptide
amyloid beta-protein (17-42): a component of diffuse amyloid deposits isolated from brains of patients with alzheimer's disease; amino acid sequence given in first source
amyloid beta-protein (21-35): highly selective agonist of substance p receptors (nk-1)
amyloid beta-protein (25-35): causes activation of cytoplasmic calcium in neurons
amyloid beta-protein (29-40): a non-fibrillar portion of amyloid-beta protein
amyloid beta-protein (3-42), pyroglutamyl(3)-: mediates neurodegenerative changes in alzheimer's disease; a major component of amyloid deposits in that disease
amyloid beta-protein (31-35): a fragment of amyloid beta protein containing amino acids 31-35 did not promote cell death in human vascular endothelial cells; has been sequenced
amyloid beta-protein (35-25): a fragment of amyloid beta protein containing amino acids 35-25 did not promote cell death in human vascular endothelial cells; has been sequenced
amyloid beta-protein (35-43): an amyloid beta protein which deposits in the brain of patients with alzheimer's disease; has been sequenced
amyloid beta-protein (40-1): a synthetic control peptide; has the same molecular weight as amyloid beta-protein (1-40) but the reverse primary sequence
amyloid beta-protein p3, human: a naturally occurring beta-amyloid derivative that has a unique & potentially pathogenic immunohistochemical profile in alzheimer's disease brain; induces pro-inflammatory cytokine and chemokine production; partial amino acid sequence given in first source
amyloid beta-protein precursor 770 (713-730): a highly fibrillogenic synthetic peptide homologous to residues 713-730 of betapp770
amyloid beta-protein precursor C-terminal fragment beta, human: product of action of beta-site app cleaving enzyme on amyloid beta-protein precursor
amyloid enhancing factor: glycoprotein that is distinct from either of the 2 known secondary amyloid proteins, aa or p-component; isolation and molecular characterization have not been performed
amyloid fibril protein AS-SAM: unique amyloid fibril protein isolated from senescence-accelerated mice; mw 5200; found in mice with amyloidosis
amyloid fibril protein ASc2: derived from the atrial natriuretic peptide; mw 3.5 kda
amyloid fibril protein Alambda (ESI): has been sequenced; isolated from a patient with multiple sclerosis
amyloid fibril protein EPS: carbohydrate-containing amyloid protein of immunoglobulin gamma light chain origin; isolated from liver of patient with an immunocyte dyscrasia of the igm type; mw 20,000; amino acid sequence given in first source
amyloid fibril protein Es492: from immunoglobulin gamma-light chain; contains carbohydrate; amino acid sequence given in first source
amyloid fibril protein Nis: found in patient with medullary carcinoma of the thyroid; mw 17,000; amino acid composition given in first source
amyloid fibril protein RS: n-terminal aa sequence given for first 34 residues; mw approx 16,000
amyloid fibril protein SKO-III: mw 14kd; associated with familial amyloidotic polyneuropathy of jewish type; prealbumin variant with isoleucine replaced by phenylalanine at position 33
amyloid prealbumin: abnormal prealbumin; met substituted for val at position 30; amino acid sequence given in first source
amyloid precursor protein, carboxy-terminal 100 residues: consists of the beta-amyloid peptide betaa4 (40-43 residues) and the adjacent cytoplasmic domain
amyloid protein 758: n-terminal aa sequence of major subunit protein given in first source
amyloid protein AL: al refers to an amyloid composed of immunoglobulin light chains; amino acid
amyloid protein AR, human: isolated from patient with primary amyloidosis; consists of 154 amino acid residues
amyloid protein ATK: isolated from human ureter obstructed by tumor-like infiltration with amyloid; derived from lambda ii-type immunoglobulin light chain; amino acid
amyloid protein BAN: kappa i al amyloid protein; 126-amino acid protein; amino acid sequence given in first source
amyloid protein GRA, human: produces articular amyloid deposits and the shoulder-pad sign; amino acid
amyloid-beta(40-1)-Gly8-1-40 peptide: consists of the reverse sequence of abeta(1-40) linked to abeta(1-40) via an eight residue glycine linker; inhibits abeta1-40 aggregation
amyloidogenic apolipoprotein A-II, mouse: an allelic variant of apolipoprotein a-ii which is a major apolipoprotein of serum high density lipoprotein (hdl); apoa2c protein deposits are also known as mouse senile amyloid fibrils associated with amyloidosis
amylolysin, Bacillus amyloliquefaciens GA1: a type-b lantibiotic
amylopectin sulfate: antipeptic, anti-ulcer, mucin-like agent prepared by sulfation of potato amylopectin
amylopectin synthase: from eimeria tenella; catalyzes udpglucose alpha 1,4-glucan alpha-4-glucosyltransferase forming amylopectin, similar to glycogen synthase in eukaryotes
amylopullulanase: has both pullulanase (ec 3.2.1.41) and alpha-amylase (ec 3.2.1.1) activities; apua encodes alkaline amylopullulanase from bacillus; amino acid ; genbank m97665
amylosin, Bacillus: a heat stable toxin from bacillus subtilis, b. mojavensis and b. amyloliquefaciens
amylovorin L471: a bacteriocin purified from lactobacillus amylovorus; n-terminal amino acid
amylxanthane: decreases norepinephrine & epinephrine content in chromaffin tissue of rainbow trout; rn given refers to parent cpd
amylyte: rice water treated with amylase to yield an electrolyte solution containing short polymers of glucose; used to treat acute diarrhea
amythiamicin C: polythiazole-containing cyclic peptide antibiotic from amycolatopsis
an-gong-niu-huang wan: has neuroprotective activity; used to treat cerebral diseases; consists of bubali cornu, bovis calculus, cinnabar, rabiagar, scutellariae radix, coptidis rhizoma, curcumae radix, gardeniae fructus, margarita, moschus, and borneolum syntheticum
ana protein, Drosophila: secreted by glia, inhibits neuroblast proliferation; from drosophila anachronism locus; 474 amino acid residues; amino acid sequence given in first source; refseq nm_057690
anabaenopeptin 908: isolated from planktothrix agardhii cya 126/8
anabaenopeptin 915: isolated from planktothrix agardhii cya 126/8
anabaenopeptin B: from cyanobacteria planktothrix (oscillatoria) rubescens
anabaenopeptin F: inhibited serine/threonine protein phosphatases pp1 and pp2a; from the cyanobacteria planktothrix (oscillatoria) agardhii and p. rubescens
anabaenopeptin G: isolated from planktothrix agardhii hub 011
anabaenopeptin H: a carboxypeptidase a inhibitor isolated from the cyanobacterium oscillatoria agardhii
anabol: preparation isolated from membranes of lactobacillus bulgaricus; rn from toxlit 4/88
anabsinthin: a guaiac-dimer from pulicaria gnaphalodes (asteraceae)
anacardic acid: isolated from anacardium occidentale; monophenol monooxygenase inhibitor
anacardoside: phenolic glucoside from the seeds of semecarpus anacardium
anaerobic ribonucleotide reductase: found in bacteriophage t4, s. aureus, and in escherichia coli
anaferon: a preparation of antibodies against gamma-interferon in ultralow doses; used to treat children with weak immune systems
anagalloside B: a molluscicidal pentacyclic triterpenoid saponin from the plant anagallis arvensis (primulaceae)
anagrelide: imidazoquinazoline derivative which lowers platelet count probably by inhibiting thrombopoiesis and reduces platelet aggregation; used for thrombocythemia
anagyrine: rn given refers to (7r-(7alpha,7abeta,14alpha))-isomer
analgesin: contains 2 parts ether to 1 part vegetable oil with 0.5% novocaine base; do not confuse with analgesine, a synonym in chemline to antipyrine (mh)
analgesin-HJ(I5T), Hyla japonica: analgesic peptide from the skin of tree frog
analgesin-HJ, Hyla japonica: analgesic peptide from the skin of tree frog
ananain: found in pineapple stem; shows strong inhibition by chicken cystatin; immunologically distinct from bromelain & has different substrate specificity
ananolignan F: from the seeds of kadsura ananosma, showed significant neuroprotective effects in an in vitro assay
ananolignan L: from the seeds of kadsura ananosma, showed significant neuroprotective effects in an in vitro assay
anantin: atrial natriuretic factor antagonist; from streptomyces coerulescens; consists of 17 natural amino acids which form a ring system; mf c90-h111-n21-o24; binds to receptor of atrial natriuretic factor
anantine: rn given for (s-(e))-isomer; component of african folk medicine derived from cynometra
anaphase-promoting complex subunit 10 protein, Arabidopsis: refseq nm_127387
anaphylatoxin receptor C3a, rat: refseq nm_032060.1; np_114449.1
anapsos: glycoside composed of glucose & fructose & a triterpenic aglycon; isolated from mashed & dried rhizomes of calaguala polypodium leucotomoss
anaritide: anaritide is a synthetic 25-amino acid atrial natriuretic factor corresponding to the (102-126) sequence of atrial natriuretic factor prohormone; wy-47,663 is the acetate salt; rn & structure given in usan; see also atrial natriuretic factor; alpha-atrial natriuretic peptide, human (nm); atrial natriuretic peptide, rat (nm)
anasteroside A: from the patagonian starfish anasterias minuta (phylum echinodermata, class asteroidea)
anasteroside B: from the patagonian starfish anasterias minuta (phylum echinodermata, class asteroidea)
anatoxin I: found mainly in anabaena; was indexed to cyanobacterial toxin (marine toxins). isolated from many salt-tolerant freshwater cyanobacteria
anatoxin a: found in anabaena; was indexed to cyanobacterial toxin (marine toxins) 1978-2006; also see anatoxin-a(s)
anatoxin-a(s): found in anabaena; was indexed to cyanobacterial toxin (marine toxins) 1986-2006; also see anatoxin-a(s)
anatoxin-b: found in anabaena; was indexed to cyanobacterial toxin (marine toxins)
anatoxin-b(s): found in anabaena; was indexed to cyanobacterial toxin (marine toxins)
anatoxin-c: found in anabaena; was indexed to cyanobacterial toxin (marine toxins)
anatoxin-d: found in anabaena; was indexed to cyanobacterial toxin (marine toxins)
ancisheynine: n,c-coupled naphthylisoquinoline alkaloid from ancistrocladus heyneanus
ancistectorine D: has both antiprotozoan and antineoplastic activities; isolated from the chinese liana, ancistrocladus tectorius
ancistrobenomine A: 5,1'-coupled naphthylisoquinoline alkaloid from the stem bark of highland liana ancistrocladus sp.
ancistrobenomine B: antineoplastic alkaloid from the chinese liana ancistrocladus tectorius
ancistrofuran: isolated from the defensive secretions of the west african termite ancistrotermes cavithorax
ancistroheynine B: has been isolated from the leaves of the indian liana ancistrocladus heyneanus wall
ancistron N: from aspidelaps lubricus venom; thrombin-like enzyme; substitute for batroxobin
ancistrotanzanine A: 5,3'-coupled naphthylisoquinoline alkaloid from ancistrocladus tanzaniensis (ancistrocladaceae)
ancistrotanzanine C: naphthylisoquinoline alkaloid from ancistrocladus tanzaniensis
ancistrotectoquinone A: 7,3'-coupled naphthylisoquinoline isolated from the leaves and stems of ancistrocladus tectorius (ancistrocladaceae)
ancistrotectoquinone B: 7,3'-coupled naphthylisoquinoline isolated from the leaves and stems of ancistrocladus tectorius (ancistrocladaceae)
ancovenin: from streptomyces sp.; dialysable peptide composed of 16 amino acid residues
andavadoic acid: cyclic peroxide from the marine sponge plakortis aff simplex
andecaliximab: anti-matrix metalloproteinase-9 monoclonal antibody for treatment of ulcerative colitis and rheumatoid arthritis
andirobicin A glucoside: ; a norcucurbitacin isolated from fevillea trilobata
andirobicin B glucoside: ; a heptanorcucurbitacin isolated from fevillea trilobata
andirolide W: from the flower oil of andiroba (carapa guianensis, meliaceae)
andirolide X: from the flower oil of andiroba (carapa guianensis, meliaceae)
andirolide Y: from the flower oil of andiroba (carapa guianensis, meliaceae)
andrastin D: inhibits protein farnesyltransferase; isolated from penicillium
androcin, Androctonus bicolor: cysteine-rich venom peptide that induces akinesia and anxiety-like symptoms in mice
androgen-dependent secretory protease: glycoprotein from dog prostate; hydrolyzes arginine & lysine-containing amide & ester protease substrates
androgen-inducible aldehyde reductase: 80% homologous to rat aflatoxin b1 aldehyde reductase; isolated from rat prostate; amino acid ; genbank ab037424
androgenic gland hormone (Armadillidium): protein produced by the androgenic gland of armadillidium vulgare; is responsible for male sexual differentiation in crustaceans; consists of two molecular forms agh i & agh ii; monomeric proteins with mw 17kda & 18.3kda , respectively; agh i has 157 amino acids, agh ii has 166 amino acids
andrographolide sulfonate: improves alveolar hypercoagulation and fibrinolytic inhibition and attenuates pulmonary inflammation
andrographolide-4: has antineoplastic activity; isolated from andrographis paniculata
androsin: phenol glycoside which prevents allergen & platelet-activating factor induced bronchial obstruction in guinea pigs in vivo prior to inhalation challenge
androsol acetate: russian drug; steroidal cpd in androstane series; no other info avail 2/92
androst-16-en-3 beta-ol sulfotransferase: a beta sulfotransferase
androst-16-en-3-ol glucuronide: a component of human sweat
androst-16-en-3-ol sulfoconjugate: physiologically active steroid; rn given refers to (3beta,5alpha)-isomer; rn & n1 from 9th ci form index
androst-16-en-3-one: boar taint steroid; rn given refers to (5alpha)-isomer
androst-4-ene-3 beta,17 beta-diol dicyclopentylpropionate: used in treatment of aplastic anemia
androst-4-ene-3 beta,17 beta-diol dienanthate: used in treatment of aplastic anemia
androst-5-en-3-ol: rn given refers to (3beta)-isomer
androst-5-ene-3,7,16,17-tetrol: he-3177 is the (3beta,7beta,16alpha,17beta)-isomer; he-3413 is the (3alpha,7beta,16alpha,17beta)-isomer; a steroidal anti-inflammatory agent
androsta-1,4,6-triene-3,17-dione: blocks aromatization of testosterone to estradiol; aromatase antagonist
androsta-5,16-dien-3 beta-ol synthetase: nadph- & o(2)-dependent; converts progesterone to 4,16-androstadien-3-one and converts pregnenolone to androstadienol
androstenedione 17-alpha-oxidoreductase: forms epitestosterone; was mapped to testosterone dehydrogenases (85-93); index medicus see under 17-hydroxysteroid dehydrogenases (85-90)
androsterone sulfotransferase: may be an isoenzyme of ec 2.8.2.2 (hydroxysteroid sulfotransferase)
anecortave acetate: derived from cortisone (11 oh replaced by 9-11 double bond)
anemaran: from anemarrhena asphodeloides (liliaceae) rhizomes
anemarchalconyn: from the rhizomes of anemarrhena asphodeloides
anemarcoumarin A: from the rhizomes of anemarrhena asphodeloides
anemone toxin BcIII (Bunodosoma caissarum): has 48 aa residues with 6 half-cystine residues; sequence has homology with type 1 long sea anemone neurotoxins; aa sequence given in first source
anemone toxin BgTX8 (Bunodosoma granolifera): isolated from bunodosoma granolifera; mw: 109,000
anemonin: a furanone dimer found in ranunculaceae; do not confuse with anemonine which is 5-(carboxymethyl)-1,1-dimethylimidazolium hydroxide inner salt; ranunculine is hydrolyzed to protoanemonin which dimerizes to anemonin
anemoside A3: induces relaxation in rat renal arteries; from the root of pulsatilla chinensis
anethofuran: ; from dill weed oil of plant, anethum graveolens l
anethole: an isomer of estragole; structurally similar to capsaicin; has some neurological and insecticidal and skin absorption effects; rn given refers to unspecified stereoisomer
angR protein, Vibrio anguillarum: a trans-acting transcriptional regulator for the iron uptake system of the bacterium; allows the bacterium to survive in iron deprived environment of fish; amino acid sequence given in first source; from vibrio anguillarum; modulates fe2+ regulated transcription & is regulated by fe2+ at the transcriptional level; genbank m34504
angelmarin: from angelica pubescens, anti-cancer agent able to eliminate the tolerance of cancer cells to nutrient starvation
angelmicin A: from microbispora sp.aa9966; mf c85-h112-o38; protein-tyrosine kinase inhibitor
angelmicin B: from microbispora sp.aa9966; mf c85-h112-o37; protein tyrosine kinase inhibitor
anginex peptide: a synthetic 33-mer anti-angiogenic peptide with antineoplastic activity; amino acid
angiocal protein: an engineered anticalin and vegf-a antagonist that is based on tear lipocalin
angiogenic inhibitor protein, Oryctolagus cuniculus: identical to prothrombin kringle-2 domain; inhibits growth of basic fibroblast growth factor-stimulated capillary endothelial cells; isolated from rabbit serum; amino acid ; genbank af080065
angiogenin: human tumor protein which stimulates growth of blood vessels; contains 123 amino acids; member of the pancreatic ribonuclease superfamily; mw 14,400
angiohypotensin: blood-borne selective inhibitor of the release of noradrenaline from the nerve terminals of resistance vessels
angiolam A: isolated from angiococcus disciformis strain an d30; ; mf c34-h53-n-o7
angiolysin: hormome from renal medulla from pig kidneys; an extremely potent vasodilator, even stronger than medullipin
angiopoietin 4: mouse refseq nm_009641, human refseq nm_015985
angiostatin4.5 protein, mouse: a naturally occurring isoform of angiostatin that contains the first four kringle domains and 85% of the fifth kringle domain of plasminogen
angiostatin4.5, human: is a naturally occurring human angiostatin isoform, consisting of plasminogen kringles 1-4 plus 85% of kringle 5 (amino acids lys78 to arg529)
angiotensin A: is a human strong vasoconstrictive angiotensin-derived peptide, most likely generated by enzymatic transformation through mononuclear leukocyte-derived aspartate decarboxylase
angiotensin I (Phe 8-His 9) hydrolase: cleaves the cooh-terminal dipeptide his(9)-leu(10) from the decapeptide angiotensin i
angiotensin I degrading enzyme: from rat vascular walls; ph optimum=7.75; not affected by inhibitors of angiotensin i converting enzyme
angiotensin II (1-6): rn given refers to cpd with unknown position 5
angiotensin II degradation factor: cysteine protease from porcine endothelial cells degrades human angiotensin ii, [val5]-angiotensin ii and [asn1, val5]-angiotensin ii; does not act on angiotensin i; 154kda; ph optimum 7.0
angiotensin II, 1-(4-azidobenzoic acid)-Ile(8)-: angiotensin ii antagonist
angiotensin II, cyclo(Sar(1)-Cys(3)-Mpt(5))-: a cyclic angiotensin analog
angiotensin II, cyclo(Sar(1)-HCys(3)-Mpt(5))-: a cyclic angiotensin analog
angiotensin II-producing serum enzyme III: not indentical to renin, cathepsin g, tonin, enzyme i, enzyme ii, the calcium-dependent angiotensin i-converting enzyme or the calcium-independent carboxy peptidase; inhibited by alpha-1-antitrypsin, diisopropylfluorophosphate & lima bean trypsin inhibitor; not inhibited by captopril, teprotide or enalapril; ph optinum=7.7
angiotensin converting enzyme secretase: converts ace from a membrane-bound to a soluble form; not inhibited by thiol, serine or acid enzyme inhibitors but is inhibited by edta and 1,10-phenanthroline
angiotensin-producing serum enzyme II: not identical to renin, ph optimum=4.7; easily inhibited by pepstatin; precursor proenzyme ii is activated by plasmin
angiotensin-related carboxypeptidase: rat and bovine brain synaptosomal enzyme can hydrolyze angiotensin i to des-leu angiotensin i, but no further
angiotensinase: deleted entry from enzyme nomenclature, 1992; was mh 1968-93 (as prov 1964-68); use peptide peptidohydrolases to search angiotensinase 1966-93
angiotensinogen (1-14): asp-arg-val-tyr-ile-his-pro-phe-his-leu-leu-val-tyr-ser; mw 1759; human = asp-arg-val-tyr-ile-his-pro-phe-his-leu-val-ile-his-asn
angiotensinogen gene-inducible enhancer-protein 1: sequence specific apre-binding protein; amino acid sequence given in first source
angiotrofin: russian drug; insulin-free bovine pancreatic tissue extract containing some kallikrein; do not confuse with drug of same name containing ifenprodil
anglerfish peptide YG: from brain & islet organs of anglerfish (lophius americanus); has significant homology with neuropeptide y
angocin Anti-Infekt N: extract of nasturtium and horseradish; has anti-infective activity
angubindin-1: a novel binder to angulin-1 and -3 that was recently developed from clostridium perfringens iota-toxin; this portion of the protein is non-toxic
anguibactin: a peptide biosynthesized by nonribosomal peptide synthetases; siderophore isolated from vibrio anguillarum 775 harboring the pjm1 plasmid
anguivine: a steroid alkaloid glycoside; from the roots of solanum anguivi
angustatin, Dendroaspis angusticeps: platelet-aggregation inhibitor from venom
angustibalin: sesquiterpene lactone from balduina angustifolia (pursh) robins
angustidine: corynanthe alkaloid from strychnos angustiflora
angustilodine: from the leaves of the malayan plant alstonia angustiloba
angustinine: a benzopyridoquinolizine alkaloid from alangium lamarckii
anhuienoside C: an active component of the anemone flaccida preparation, di wu, used to treat rheumatism
anhydroelastase: catalytically inert derivative of elastase in which the active-site residue ser-195 has been converted to a dehydroalanine residue
anhydroicaritin 3-O-rhamnosyl-1-2-rhamnoside: isolated from epimedium koreanum
anhydrolevuglandin E2: anhydrolevuglandin e2-like activity found in extracts & media from uteri of rats
anhydrolevulgandin D2: ; inhibits the uterotonic activity of prostaglandins f2alpha and d2
anhydromarmeline: alpha-glucosidase inhibitor isolated from leaves of aegle marmelos
anhydroperoxycostunolide: from laurel (laurus nobilis l.)
anhydrosafflor yellow B: one of the major active water-soluble pigments from carthamus tinctorius, which has been found to inhibit adp-induced platelet aggregation and possess significant antioxidant activity
anhydrotetracycline oxygenase: streptomyces aureofaciens enzyme catalyzing penultimate reaction of tetracycline biosynthesis, hydration of anhydrotetracycline to dehydrotetracycline
aniA protein, Neisseria gonorrhoeae: 54 kda outer membrane protein of neisseria gonorrhoeae; nucleotide sequence of the structural gene, ania, encoding pan 1 given in first source
anicemycin: an antineoplastic antibiotic that inhibits anchorage-independent tumor cell growth
anikasin peptide, Pseudomonas fluorescens: has amoebicidal activity
anileridine: minor descriptor (64-86); on line & index medicus search isonipecotic acids (68-86); rn given refers to parent cpd
anilinoquinazoline: precursor for synthesis of 6-(2-substitutedacetamido)-4-anilinoquinazolines egfr-erk signal transduction inhibitors
anillin: a 190 kda contractile ring protein that cycles from the nucleus to the cell cortex from drosophila; amino acid sequence given in first source; genbank x89858
animacroxam: a histone deacetylase (hdac) inhibitor for the treatment of testicular germ cell tumors (tgct)
anion exchange protein 4, rat: rat homolog of human & rabbit ae4; genbank ab024339
anion-sensitive ATPases: putative anion sensitive atpases, they may be involved in anion transport
anionic ligand-binding receptor, Drosophila: endogenous receptor that binds anionic ligands (als); albr is internalized into rab5-positive endosomes, whereas the major portion of the fluid phase is taken up into rab5-negative endosomes
anionic peroxidase: isolated from zucchini, cucurbita pepo; cevi-1 isolated from tomato; amino acid ; genbank y17192
anionic polypeptide fraction, human: major protein of the biliary lipoprotein complex; can be considered a marker of bile secretion disorders
anionic polypeptide fraction, rat: major protein of the biliary lipoprotein complex; can be considered a marker of bile secretion disorders
aniracetam: mental performance enhancer; rn given refers to cpd with locant for methoxy group in position 4 & from usan 1983
anisatin: rn given refers to cpd without isomeric designation; also see 2-oxo-6-deoxyneoanisatin
anisucoumaramide: bioactive cpd from clausena anisum-olens
anithiactin A: acetylcholinesterase inhibitor from a mudflat-derived streptomyces sp.
anithiactin B: acetylcholinesterase inhibitor from a mudflat-derived streptomyces sp.
anithiactin C: acetylcholinesterase inhibitor from a mudflat-derived streptomyces sp.
ankaferd blood stopper: a hemostatic, folkloric medicinal plant extract derived from t. vulgaris, g. glabra, v. vinifera, a. officinarum, and u. dioica
anmindenol A: an inducible nitric oxide synthase inhibitor from a marine-derived streptomyces sp.
anmindenol B: an inducible nitric oxide synthase inhibitor from a marine-derived streptomyces sp.
anmontanin A: a monotetrahydrofuran annonaceous acetogenin from annona montana
anmontanin B: a monotetrahydrofuran annonaceous acetogenin from annona montana
anmontanin C: a monotetrahydrofuran annonaceous acetogenin from annona montana
annetocin: an oxytocin-vasopressin related peptide from eisenia foetida; potentiates spontaneous contractions of the gut , pulsatory contractions & bladder-shaking movement of the nephridia
annexin 1, Arabidopsis: a putative redox sensor with peroxidase activity; genbank af083913
annexin A1 peptide (2-26): an anti-inflammatory peptide derived from human lipocortin 1 n-terminus region; amino acid sequence given in first source
annexin A4, Bos taurus: p41 is a disulfide-linked dimer of p33; binds sialoglycoproteins and glycosaminoglycans; genbank d78178
annimycin: polyeneoic acid amide derived from streptomyces asterosporus
annocatacin A: a bis-tetrahydrofuran annonaceous acetogenins from annona muricata
annocatacin B: a bis-tetrahydrofuran annonaceous acetogenins from annona muricata
annocherimolin: cytotoxic annonaceous acetogenin from annona cherimolia seeds:
annoglabayin: a dimeric kaurane diterpenoid from the fruits of annona glabra (annonaceae)
annoglacin A: a bioactive mono-tetrahydrofuran acetogenin from annona glabra
annoglacin B: a bioactive mono-tetrahydrofuran acetogenin from annona glabra
annomolin: cytotoxic annonaceous acetogenin from annona cherimolia seeds:
annomontine: antileishmanial pyrimidine-beta-carboline alkaloid from the bark extract of annona foetida
annomuricin E: a mono tetrahydrofuran ring acetogenin from leaves of annona muricata
annonacin: linear polyketide isolated from extracts of the stembark of annona densicoma
annonidin B: a prenylated bisindole from annonidium mannii (annonaceae)
annonin VI: inhibits e. coli nadh:quinone oxidoreductase (ndh-1)
annosquamosin A: a kaurane diterpenoid from fruits of annona squamosa
annosquamosin B: a kaurane diterpenoid from fruits of annona squamosa
anntoxin, Hyla annectans: genbank fj598043, pdb/2kcr
annulatophenone: isolated from the methanol extract of the herb of hypericum annulatum
annulin: 97 kda membrane-associated protein expressed at limb segment boundaries in the grasshopper embryo; homologous to protein cross-linking transglutaminases; amino acid sequence given in first source
annulohpoxylotol A: an nf-kappab inhibitor; isolated from annulohypoxylon truncatum
annulohpoxylotol B: an nf-kappab inhibitor; isolated from annulohypoxylon truncatum
annulohypoxyloman A: from the endophytic fungus annulohypoxylon truncatum of zizania caduciflora
annulohypoxyloman B: from the endolichenic fungus sporormiella irregularis
annulohypoxyloman C: from the endophytic fungus annulohypoxylon truncatum of zizania caduciflora
anomalin: ; rn given refers to (z)-isomer; rn for cpd without isomeric designation not avail 10/90
anonaine: smooth muscle relaxant; aporphine alkaloid isolated from roots of annona cherimolia
anonamine: macrocyclic secopyrrolizidine alkaloid from senecio anonymus
anophelin protein, Anopheles albimanus: anti-thrombin peptide isolated from salivary glands of the mosquito anopheles albimanus; amino acid ; genbank af125095
anoplin: an antimicrobial peptide from the venom of the solitary wasp anoplius samariensis; peptide
anordiol: rn given refers to (2alpha,5alpha,17alpha)-isomer
anordrin: rn given refers to (2beta,5alpha,17alpha)-isomer
anpirtolin: non-opiate analgesic; ; rn given refers to the (14c)-labeled cpd
anrukinzumab: an anti-interleukin 13 monoclonal antibody
ansalactam A: produced by a marine sediment-derived bacterium of the genus streptomyces
ansalactam B: hexacyclic metabolite isolated from marine-derived streptomyces bacterium
ansalactam C: tetracyclic metabolite isolated from marine-derived streptomyces bacterium
ansalactam D: pentacyclic metabolite isolated from marine-derived streptomyces bacterium
ansellone A: from the nudibranch cadlina luteromarginata and the sponge phorbas
antagglutinin (boar): specific protein synthesized by the boar epididymidis; mw 120kda
antago-miR-155, human: oligonucleotide mir-155 antagonist; may be powerful tool to silence specific mirnas
antagomir-16: synthetic single-stranded rna molecule; mir-16 antagonist
antagomir-223: inhibits apoptosis, promotes angiogenesis and functional recovery in rats with spinal cord injury
antamanide: cyclic decapeptides otained from the green death cup toadstool (amanita phalloides). acts as an antidote against poisoning by phallotoxins by preventing accumulation & absorption of the toxin in the liver; minor descriptor (75-86); on-line & index medicus search peptides, cyclic (75-86)
antamanide, Phe(4)-Val(6)-: rn given refers to all (l)-isomer
antapin: antimicrobial cationic peptide isolated from venom of the bee anthophora plumipes
antarth: polyherbal preparation that protects against the doxorubicin-induced toxicity without compromising its antineoplastic activity; contains extracts of salai guggul (boswellia serrata, 150 mg), shuddha guggul (commiphora mukul, 150 mg), ashwagandha (withania somnifera, 100 mg), chopchini (smilax china, 100 mg), gokshura (tribulus terrestris, 100 mg), guduchi (tinospora cordifolia, 100 mg), haldi (curcuma longa, 100 mg), kulanjan (alpinia galangal, 100 mg), methi (trigonella foenum-graeceum, 100 mg), nirgundi (vitex negundo, 100 mg), punarnava (boerhaavia diffusa, 100 mg), trikatu (piper longum, piper nigrum, zingiber officinale, 100 mg), triphala (terminalia chebula, terminalia belerica, emblica officinalis, 100 mg) and shuddha shilajit (asphaltum, 50 mg)
antatollamide A: dimerized cyclic hexapeptide from colonial ascidian didemnum molle
antatollamide B: dimerized cyclic hexapeptide from colonial ascidian didemnum molle
antazirine: rn refers to (4z)-isomer; isolated from dysidea fragilis
antazoline sulfate, naphazoline mononitrate drug combination: combination of antazoline phosphate & naphazoline hcl in soln with polyvinyl alcohol, edetate sodium & benzalkonium chloride; rn given refers to antazoline sulfate[1:1]salt mixt. with naphazoline mononitrate
antazoline, xylometazoline drug combination: for allergic & inflammatory diseases of the outer eye; contains antazoline & xylometazoline
antcin A: from antrodia camphorata, exerts anti-inflammatory effect via mimicking glucocorticoids
antcin H: ergostane-type triterpenoid from antrodia cinnamomea
antcin K: has antineoplastic activity; isolated from antrodia cinnamomea
antennal-specific protein 1, Apis mellifera: a queen pheromone-binding protein isolated from the honeybee; amino acid
anthelminthicol A: an anti-inflammatory from hydnocarpus anthelminthica seeds
antheminone A: isolated from the leaves of anthemis maritima; exhibited significant antiproliferative activity against leukemia cells
antheminone B: isolated from the leaves of anthemis maritima; exhibited significant antiproliferative activity against leukemia cells
antheminone C: isolated from the leaves of anthemis maritima; exhibited significant antiproliferative activity against leukemia cells
anthocleistenolide: a rearranged nor-secoiridoid derivative from the stem back of anthocleista vogelii
anthocyanidin reductase, Ginkgo biloba: reaction: a flavan-3-ol + 2 nad(p)+ = an anthocyanidin + 2 nad(p)h + h+; amino acid
anthocyanidin synthase: a 2-oxoglutarate-dependent oxygenase that catalyzes the conversion of leucoanthocyanidin to anthocyanidin with concomitant conversion of 2-oxoglutarate to succinate, water, and carbon dioxide; amino acid ; isolated from perilla frutescens; genbank ab003779
anthocyanin1 protein, Petunia x hybrida: a petunia basic helix-loop-helix protein that directly activates transcription of structural anthocyanin genes; controls pigment synthesis, vacuolar ph, and seed coat development; has been sequenced; do not confuse with an1 protein/gene product (anther ear1 protein)
anthopleurin-A: cardiotonic agent from the sea anemone anthopleura xanthogrammica
anthopleurin-Q: a purified polypeptide extracted from marine invertebrates: anthopleura
anthopogochromane: isolated from the chinese medicinal plant rhododendron anthopogonoides
anthopogochromene A: isolated from the chinese medicinal plant rhododendron anthopogonoides
anthorhododendrin: total flavone glucosides isolated from rhododendron anthopogonoides maxim; pronounced expectorant effect in mice
anthra(2,1-c)(1,2,5)thiadiazole-6,11-dione: has antineoplastic activity
anthracene-9-carbonyl chloride: used as derivatizing agent for determination of diethylene glycol
anthraceno(1,2-c)(1,2,5)selenadiazolo-6,11-dione: has antineoplastic activity
anthraglycoside A: from polygonum cuspidatum sieb. et zucc
anthraglycoside B: from polygonum cuspidatum sieb. et zucc
anthranilate 2,3-dioxygenase(deaminating): anthranilate hydroxylase is a synonym but also refers to ec 1.14.12.1 & ec 1.14.16.3; as of 1992 reclassified from ec 1.14.2.2 to ec 1.14.13.35; encoded by antabc
anthranilate N-hydroxycinnamoyl benzoyltransferase: catalyzes n-acylation of anthranilate by hydroxycinnamoyl-coa or benzoyl-coa; isolated from the carnation dianthus caryophyllus; has been sequenced; genbank z98758
anthranilate aggregate: enzyme aggregate containing anthranilate synthetase & antrhanilate phosphoribosyltransferase
anthranilate monooxygenase: catalyzes the hydroxylation of anthranilate to hydroxyanthranilate in the presence of tetrahydropteridine & molecular oxygen; anthranilate hydroxylase is a synonym for this and ec 1.14.12.1 and ec 1.14.13.35 (formerly ec 1.14.12.2)
anthranilate synthase, glutamine amidotransferase subunit: a glutamine amidotransferase subunit involved in the synthesis of both folic acid and l-tryptophan; this is component ii of anthranilate synthase; don't confuse with gmp synthase (glutamine hydrolysing), also referred to as glutamine amidotransferase
anthranilic acid: rn given refers to parent cpd; structure in negwer, 5th ed, #565
anthraquinone 1-carboxylic acid: antifungal compound in cassia laevigata
anthraquinone sulfonate: rn given refers to cpd with unspecified acid locant
anthrax toxin: consists of 3 separate proteins: pa (protective antigen/factor), ef (edema factor) & lf (lethal factor); these three are nontoxic proteins that associate in binary or ternary combinations to form toxic complexes at the surface of mammalian cells; bacillus anthracis calmodulin-dependent adenylate cyclase is component of ef protein, is a zinc-dependent metalloprotease; pa63 is a proteolytic fragment of pa83
anthricin: antitumor constituent from anthriscus sylvestris (l.) hoffm
anthriscifoldine A: diterpenoid alkaloid from delphinium anthriscifolium var. savatieri
anthriscifoldine B: diterpenoid alkaloid from delphinium anthriscifolium var. savatieri
anthriscifoldine C: diterpenoid alkaloid from delphinium anthriscifolium var. savatieri
anthrolysin O, Bacillus anthracis: a cholesterol-dependent cytolysin (cdc) that specifically targets toll-like receptor 4 (tlr4) and acts together with lethal toxin to induce macrophage apoptosis
anthrotainin: ; isolated from gliocladium catenulatum; substance p antagonist
anti-C100-3: an anti-hepatitis c antibody also found in sera of patients with hbs antigen-positive chronic liver diseases; see also hepatitis c protein c100
anti-CASPR2 autoantibody: autoantibodies against contactin-associated protein-like 2 (caspr2). presence of anti-caspr2 auto antibodies is associated with cortical dysplasia-focal epilepsy syndrome
anti-CD20Fab-LDM protein: inhibits beta-cell lymphoma xenografts
anti-CP-9: found in sera of patients with hbs antigen-positive chronic liver diseases
anti-Fas monoclonal antibody: a mouse anti-human mab which cross-reacts with fas molecules from human and mouse
anti-HER2-neu peptide mimic, 1.5 kDa: a small exocyclic anti-her2/neu peptide mimic functionally similar to herceptin; specifically binds to p185her2/neu with high affinity resulting in inhibition of proliferation & disables p185her2/neu tyrosine kinases
anti-HIV-1 Rev SFv: a single chain variable fragment (sfv) construct, derived from a monoclonal antibody that binds to the hiv-1 regulatory protein rev; can be expressed intracellulary & potently inhibits hiv-1 replication; amino acid sequence given in first source
anti-KLHL12 antibody, human: biological marker for primary biliary cirrhosis
anti-LFA-1 monoclonal antibody: a monoclonal antibody that prevents renal graft rejection; odulimomab is tradename
anti-MMP-9 DNAzyme: a synthetic dnazyme for treatment of cancer
anti-Mullerian hormone receptor: mw 88 kda; a protein-serine-threonine kinase; ec2.7.11.30; expressed in fetal gonads and anti-mullerian hormone-responsive tissues, including human vulvar carcinoma cell line, a431
anti-VAChT antibody-saporin conjugate immunotoxin: a commercially available immunmotoxin with selective toxicity to cells expressing vesicular acetylcholine transporter (cholinergic neurons)
anti-alpha-fetoprotein antibody-daunomycin conjugate: potential antitumor agent with improved tumor specificity
anti-amphiphysin autoantibody: autoantibodies against amphiphysin associated with antibody-mediated autoimmune encephalomyelitis and various paraneoplastic neurologic syndromes including stiff person syndrome
anti-bothropic complex, Didelphis: anti-bothropic complex (abc) was isolated from the serum of the south american opossum; amino acid
anti-cancer number one: a 19-herb chinese formula used to treat cancer patients, were studied in f344 rats
anti-coagulant protein 5, Ancylostoma caninum: involved in blood anticoagulantion
anti-coagulant protein C2, Ancylostoma caninum: isolated from ancylostoma caninum; a novel inhibitor of tissue factor-factor viia activity; amino acid
anti-complementary arabinogalactan: from the roots of angelica acutiloba kitagawa
anti-dopamine beta-hydroxylase immunotoxin: an antibody-targeted noradrenergic lesioning tool comprised of a monoclonal antibody against the noradrenergic enzyme, dopamine beta-hydroxylase, conjugated to a saporin, a ribosome-inactivating protein
anti-dsDNA autoantibody: autoantibodies found in lupus erythematosus, systemic
anti-endothelial cell antibody: found in patients with polyarteritis nodosa as well as wegener granulomatosis
anti-epilepsy peptide, Buthrus martensii: composed of 66 amino acids; mw 8.29kda; sequence of first 50 amino acids given in first source; genbank af122003
anti-hexokinase 1 antibody, human: biological marker for primary biliary cirrhosis
anti-inhibitor coagulant complex: rn given refers to cpd with unknown mf; an activated prothrombin complex concentrate
anti-leprosy vaccine: combination of live bcg & heat-killed mycobacterium leprae derived from armadillo; cultivable mycobacterium isolated from human lepromata
anti-lipolytic factor: possibly a peptidase that acts on lipid mobilizing peptides; found in serum; suppresses lipolysis
anti-liver cytosolic protein 1: associated with anti-liver/kidney microsomal 1 (anti-lkm1); considered a more specific marker of type 2 autoimmune hepatitis than anti-lkm1
anti-pancytokeratin immunoglobulin: an anti-pancytokeratin antibody, used as a marker
anti-quadruplex DNA scFv: a quadruplex dna selective single chain autoantibody from variable motheaten mouse hybridoma with homology to telomeric dna-binding proteins; amino acid ; genbank af089740-2
anti-silencing factor 1, Leishmania major: contributes to the histone deposition during nucleosome assembly in newly replicated dna, involved in chromatin disassembly, transcription activation and in the cellular response to dna damage
anti-synaptophysin: has cell lineage-restricted activity to neurepithelial cells
anti-tac-SAP: consists of an anti-cd25 monoclonal antobody conjugated to saporin