Title: A programme of high priority Reviews for the management of patients with hip fracture: a collaboration which can inform future healthcare policy guidance
Funder: Department of Health and Social Care

Abstract: AIM To deliver Cochrane Reviews and Overviews that will best inform the management of patients with hip fracture and future NICE Guidance. SIZE OF THE CLINICAL PROBLEM Hip fracture is one of the biggest challenges facing patients and healthcare systems. Worldwide there are 1.3 million hip fractures with more than 70,000 hip fractures in the UK every year. These figures are projected to rise to more than 100,000 by 2020 in the UK and more than 6 million by 2050 worldwide.(2) The global cost of this clinical problem is estimated at 1.75 million disability adjusted life years lost and represents 1.4% of the total healthcare burden in established market economies. NEED FOR EVIDENCE Hip fracture is the focus of 29 separate Cochrane Reviews; NICE has published clinical guidance & quality standards.(10) This major health problem is the source of considerable ongoing research so there is an urgent need to maintain a high quality group of Reviews to present best evidence. PROGRAMME The focus of this project is to deliver outputs that can inform future healthcare policy for these fractures. In consultation with the editorial leads of the involved Cochrane Review Groups we have agreed to limit the scope to Products (Reviews, Overviews & network meta-analyses) that are pertinent to the management of hip fracture commensurate with the NICE Guideline (CG124). Refinement of the scope of the Products will be sought early from the one-day stakeholder (clinician, patient, researcher & policymaker) Consultation Workshop. This will be centred around the production of ‘briefs’ for the individual Products. The need for later changes will be assessed regularly by the Senior Management Group as the project progresses, for example any major alteration in the scope of the NICE guidelines. Up to date methodology, including GRADE assessments and summary of findings tables will be used; with a view to maximise the utility of the outputs for NICE Guidance.

Lay abstract: AIM To deliver Cochrane Reviews and Overviews that will best inform the management of patients with hip fracture and future NICE Guidance. SIZE OF THE CLINICAL PROBLEM Hip fracture is one of the biggest challenges facing patients and healthcare systems. Worldwide there are 1.3 million hip fractures with more than 70,000 hip fractures in the UK every year. These figures are projected to rise to more than 100,000 by 2020 in the UK and more than 6 million by 2050 worldwide.(2) The global cost of this clinical problem is estimated at 1.75 million disability adjusted life years lost and represents 1.4% of the total healthcare burden in established market economies. NEED FOR EVIDENCE Hip fracture is the focus of 29 separate Cochrane Reviews; NICE has published clinical guidance & quality standards.(10) This major health problem is the source of considerable ongoing research so there is an urgent need to maintain a high quality group of Reviews to present best evidence. PROGRAMME The focus of this project is to deliver outputs that can inform future healthcare policy for these fractures. In consultation with the editorial leads of the involved Cochrane Review Groups we have agreed to limit the scope to Products (Reviews, Overviews & network meta-analyses) that are pertinent to the management of hip fracture commensurate with the NICE Guideline (CG124). Refinement of the scope of the Products will be sought early from the one-day stakeholder (clinician, patient, researcher & policymaker) Consultation Workshop. This will be centred around the production of ‘briefs’ for the individual Products. The need for later changes will be assessed regularly by the Senior Management Group as the project progresses, for example any major alteration in the scope of the NICE guidelines. Up to date methodology, including GRADE assessments and summary of findings tables will be used; with a view to maximise the utility of the outputs for NICE Guidance.

Research activity codes: 6.3 MEDICAL DEVICES;6.4 SURGERY;7.3 MANAGEMENT AND DECISION MAKING
Health categories: INJURIES AND ACCIDENTS