Title: Marie Curie Palliative Care Research Centre, Cardiff University, Core Grant
Funder: Marie Curie

Abstract: The Marie Curie Palliative Care Research Centre aims to improve the care and well being of patients and families affected by progressive, life-threatening illness. We will achieve this by:_x000D_ 3. Undertaking high quality research of national priority which is directly relevant to patient and carer needs._x000D_ 4. Demonstrating impact through knowledge transfer and mobilization, effecting the translation of research findings into clinical practice and policy implementation._x000D_ Our alignment within robust and forward looking academic research infrastructures at both national and institutional levels will allow us to proceed from a position of methodological and collaborative strength. We will provide Wales and UK leadership in study design and implementation and be to the fore in innovative approaches to Patient and Public Involvement (PPI) and knowledge mobilization across clinical services. We have purposefully developed a distinctive combination of specific methodological expertise, and strong leadership in building collaborative frameworks, to underpin our aims and objectives._x000D_ Aim 1. Undertaking high quality research of national priority which is directly relevant to patient and carer needs. This will be achieved using our methodological and reputational strengths to build on our current portfolio of early phase, feasibility and late phase studies. We will continue to have patient and carer experience at the heart of study design and implementation, attracting further prestige funding into Wales and the UK as project leads and also as co-applicants with external colleagues. Our leadership model will support capacity building across disciplines through grant capture and cross -institutional collaboration._x000D_ Whilst our work plans focus on three thematic areas, our skill sets and collaborative network provides us with the flexibility to capably respond to the changing landscape within palliative care and healthcare structures._x000D_ The three main themes are:_x000D_ 1. Patient and Carer experience and Patient and Public Involvement (including clinical trials, prudent healthcare and shared decision-making). Theme lead: Nelson_x000D_ 2. Palliative rehabilitation (including all aspects of maintaining independence, social aspects of function) Theme lead: Byrne_x000D_ 3. Thrombosis (including patient experience and impact of thrombosis in palliative settings) Theme lead: Noble._x000D_ Whilst we will build on existing strengths within themes, our complimentary expertise and methodological skill sets will continue to be cross-cutting. Our portfolio of studies across themes will benefit from the synergy this provides in areas such as: mixed methodological expertise in embedding patient experience at the centre of study development; forefront model of PPI; evidence synthesis; clinical trials methodology; outcome measurement._x000D_ Aim 2. Demonstrating impact through knowledge transfer and mobilization, effecting the translation of research findings into clinical practice and policy implementation. Our methodological focus on patient and carer experience, and our comprehensive PPI strategy will underpin our impact and dissemination pathways. Our diverse collaborative networks, cross-organizational leadership, commitment to capacity building and multi-professional educational support will be used to deliver both academic and healthcare impact through knowledge mobilization and transfer._x000D_ We will:_x000D_ o Ensure that all studies have a clear description of future impact._x000D_ o Publish in peer review journals of high impact in our field._x000D_ o Present our findings at national and international conferences and in popular media, including social media._x000D_ o Collaborate with Marie Curie and its Wales Advisory Board to ensure mobilization of our research knowledge into practice across the organization._x000D_ o Target citations within NICE and other national guidelines._x000D_ o Contribute to Cardiff University 2020 REF return._x000D_ Milestones:_x000D_ Our measures of success will focus on:_x000D_ o Grant capture_x000D_ o Capacity building_x000D_ o Impact._x000D_ There will be demonstrable focus on both leadership and collaboration in all three areas. In particular we will achieve full involvement of multi-professional colleagues and voluntary research partners in all domains including in the demonstration of impact.


Research activity codes: 7.2 END OF LIFE CARE;7.4 RESOURCES AND INFRASTRUCTURE (DISEASE MANAGEMENT)
Health categories: CANCER AND NEOPLASMS;GENERIC HEALTH RELEVANCE