Reality check : inferential confusion and cognitive confidence as core cognitive factors across the obsessive-compulsive spectrum

Obsessive-compulsive disorder (OCD) is a severe mental health disorder that involves obsessions and/or compulsions. In light of the heterogeneity of OCD and of the presence of OCD-like thinking and behaviors in several disorders, some have argued for the necessity of a new category of obsessive-compulsive spectrum disorders. Considering the overlap between various disorders characterized by obsessionality, there is a need for the identification of common cognitive processes that underpin these disorders in order to formulate more parsimonious explanations and treatments for these conditions. A general tendency to doubt the senses and cognitive faculties appears as central to obsessional disorders. According to the inference-based approach, the obsessional doubt is elicited by a faulty reasoning process known as inferential confusion (IC), that implicates (1) a distrust of the senses, and (2) an investment in imaginary possibilities. A similar construct is low cognitive confidence, which is defined as a distrust of one’s attention, perception and memory. The overarching goal of this thesis was to examine IC and low cognitive confidence as potential transdiagnostic cognitive factors across the spectrum of obsessionality. The first thesis article evaluated the role of cognitive confidence across OCD subtypes and examined the extent to which poor cognitive confidence is associated with OCD symptomatology by conducting a systematic review with a meta-analysis. This article led to the conclusion that individuals with OCD have lower cognitive confidence than healthy controls, but that it is unclear if cognitive confidence is specific to OCD, such that the use of idiosyncratic tasks appears to be required in order to correctly capture cognitive confidence in OCD. The second thesis article furthered this investigation by examining the joint role of low cognitive confidence and IC across OCD subtypes by performing cluster analyses using a sample of 128 individuals with OCD. While cognitive confidence was found to more relevant to the checking and “just right” subtypes, IC appeared to be relevant to a wider range of OCD profiles. The third thesis article sought to examine the role of IC in eating disorders by inducing IC experimentally. Female participants with an eating disorder (n = 18) and healthy controls participants (n = 18) were recruited. Participants were assigned to one of two experimental conditions: in the High IC condition, participants watched videos with key sequences missing – provoking a distrust of the senses and lending more space for the imagination, thus triggering IC. In the Low IC condition, participants watched videos without sequences missing. The eating disorder group assigned to the High IC condition demonstrated a trend for higher levels of state IC, greater neutralization behavior and higher OCD symptoms than those who were assigned to the Low IC condition.  Taken together, the results of the present thesis underline the relevance of IC and cognitive confidence as transdiagnostic cognitive factors across the obsessive-compulsive spectrum.

Keyphrases: Obsessive-compulsive disorder, Obsessive-compulsive spectrum disorders, Eating disorders, Inferential confusion, Cognitive confidence