NCube/papyrus huggingface dataset:
Stratégies intermédiales et autoreprésentation dans l'oeuvre littéraire et les dessins-partitions d'Unica Zürn

Having recourse to many forms of expression, Unica Zürn (1916-1970) revitalizes the space of the sheet by having it take an active part in the individual writing. The “I” seems to increase thanks to “anagrammatic” games on the many mobilized signs, whether they are alphabetical, pictorial or musical. The self-representation is inspired by an unusual multidisciplinary work, which renews the aesthetics, somewhat “worn”, of the surrealist movement.  This attitude towards the sheet, where many “decomposable” and “recomposable” signs share the space, is observable in Unica Zürn’s literary work as well as in her pictorial work. The process of creation through the letter, the stroke and the musical note tends to reassert the value of the material support used by the abolition of the boundaries among the artistic disciplines, which calls for a distanced look from the reader/spectator on the work.  In order to interpret Zürn’s work in the plurality of the artistic means that are deployed, the intermedial approach will be favoured. In the first chapter of this dissertation, we will see how a certain dialog is structured between the views of the intermediality’s researchers and Unica Zürn’s work. The relation to objects will be our entry point in the intermedial subject. Through a return to the materiality of the media-related experience, we will notice that Zürn puts at the forefront the instruments and the supports to the creation, which leads to a contorted representation of oneself, space and time.  Once the parallel established between the intermediality’s concepts and Zürn’s work, we will focus on the musical aspect of the author-artist’s multidisciplinary work. The second chapter will deal with the intrusion of sound in the textual universe, which will occur through the reappropriation of the Vincenzo Bellini’s opera “Norma”. This revising is called “Les jeux à deux” and is significantly different from the original text, and is paired with drawings made by the author-artist directly on the opera’s partitions.  The multiple look placed upon the zurnian work will allow to understand that the palimpsest writing takes part in the self-representation process, through elaborating a view regarding the interrelation of literature, drawing and music, as well as the influence of this juxtaposition on the overflow of the traditional media boundaries.

Keyphrases: Dessins-partitions, Literary and pictorial self-representation, Feminine surrealism, Intermediality, Palimpsest writing, Drawings-partitions
Caractérisation de nouvelles lignées cellulaires pré-chimiothérapie et post-chimiothérapie du cancer épithélial de l'ovaire

Epithelial ovarian cancer (EOC) is the deadliest of all gynecologic cancers. The serous type of EOC is the most common form of the disease, and it accounts for more than 50% of the cases. It is often diagnosed at advanced stages where its prognosis is poor. Advanced EOC is treated mainly with chemotherapy. However, chemoresistance development eventually impedes the success of the treatments for most patients. Researchers have derived cell lines from EOC from solid tumors or from ascites. So far, there has not been EOC cell lines established from samples taken before and after chemotherapy treatments within the same patient. Our laboratory is thus the first to develop a new and powerful model of pre-chemotherapy and post-chemotherapy cell lines. All cell lines were derived sequentially from 3 different patients (1369, 2295 and 3133), from either solid tumors (TOV) or ascites (OV). We therefore characterized these new pre-chemotherapy cell lines (TOV1369TR, OV2295, TOV3133D and TOV3133G) and post-chemotherapy cell lines (OV1369(2), OV2295(2), TOV2295, OV3133 and OV3133(2)) through several approaches. Using immunohistochemistry and Western blot, we have characterized the level of expression of typical epithelial keratin markers (KRT7, KRT8, KRT18, KRT19, KRT20) to confirm the epithelial and ovarian nature of the cells. We have also analysed the expression level of important EOC markers, such as that of HER2 and p53, and found no clear difference between the pre-chemotherapy and post-chemotherapy EOC cells. Moreover, we have studied various tumorigenic features of the cell lines, such as cell proliferation (by cell count), cell migration (by the wound healing assay), 3D spheroid formation (by the hanging drop method), in vivo tumor formation in SCID mice (subcutaneous xenografts). In general, there were no notable differences between the two categories of cell lines at the cellular level, except that post-chemotherapy cell lines seemed to be unable to form compact 3D structures, contrary to some pre-chemotherapy cell lines. The obtained results would aid in better understanding the different mechanisms that malignant serous EOC tumors undergo and the progression of the disease with respect to the different treatments. Such study would allow us to gain valuable insight into the optimal treatment decisions to take for different EOC patients.

Keyphrases: Epithelial ovarian cancer (EOC), Cell model, Tumorigenic features, Pre-chemotherapy cell lines, Post-chemotherapy cell lines, Chemoresistance
L’utilisation de cultures épithéliales autologues sur les sites donneurs des grands brûlés

RATIONALE: Prompt healing of split thickness skin graft donor sites is primordial to the survival of severely burned patients. Increased mortality of patients with >50 % TBSA is attributable to the limited availability of donor sites. This study evaluated the effect of Cultured Epithelial Autograft (CEA) application on skin graft donor site healing. METHODS: All burn patients receiving CEA were prospectively included. Donor site wounds were covered with CEA except a randomly designated 7x7 cm control region. Autograft biopsies were taken to document graft harvest thickness. One half of the controls were covered with non-adherent gauze soaked in the culture media and the other controls only received a non-adherent gauze dressing. Epithelialization was objectively evaluated by scoring blinded photographs with an analogue scale. Punch biopsies of the donor sites were evaluated histologically. Repeated measures ANOVA and T-test were used. RESULTS: Between 2008 and 2009, 6 patients were enrolled for a total of 11 donor sites. The patients averaged 43.5 years, 56 % TBSA, 45 % FT-TBSA, 66 % had inhalation injury and mean length of stay was 75 days. As expected, dermatome settings and autograft thickness measured by microscope did not correlate (Pearson 0.19). There was no correlation between the percentage of epithelialization of the punch biopsies of the donor sites and the thickness of the harvest. Photographic score was significantly influenced by its treatment CEA vs Control (p=0.039) and by postoperative day (p<0.001). Mean time to healing was 8.6 days for CEA compared to 10.2 days for controls (p=0.021). Infection was noted on only one donor site. On histologic analysis, the control sites dressed with gauze soaked in the culture media healed as nicely and promptly as the CEA sheet treated region. CONCLUSION: Use of CEA on donor sites appears to stimulate epithelialization. This effect is probably mediated by stimulation of local wound healing processes rather than by engraftment of keratinocytes from the CEA sheets.

Keyphrases: Burns, Surgery, Skin grafts, Donor sites, Cultured epithelial autografts
"Un homme sur deux est une femme" : intégrer le genre dans les manuels d’histoire de la civilisation occidentale au collégial : quelques propositions

Women and gender history have developed in conjunction for more than thirty years.  Nevertheless, these domains are still not fully recognized by the university institutions, and even less by the college institutions, as the historiographical advances in these areas are being excluded from the curriculum.  Indeed, this is the situation we have observed at the college level in Quebec, following an evaluation of the narrative transmitted by French and English textbooks used in the History of western civilization courses.  In fact, thanks to an analysis of the chapters covering the early modern period, which ranges approximately from 1500 to 1800, in the most often used textbooks for the teaching of this course, we were able to establish that the history of women and the history of gender are not integrated in the narrative and that a difference exists between the narrative of the French and English textbooks. We observed that the only mandatory history course at the college level, which endeavours to form enlightened male and female citizens as well as to transmit a basic general culture, excludes half of the population of their teachings.  Thus, this work proposes three solutions to remedy this situation.

Keyphrases: History, Women, Gender, Early modern period, College-level teaching, Western civilization
Théories implicites chez les agresseurs de femmes adultes

The presence of cognitive distortions among sex offenders are considered to be highly influential in the etiology and maintenance of deviant sexual behavior. According to Ward and Keenan (1999), cognitive distortions emerge from implicit theories. Implicit theories can be defined as a network of interrelated beliefs that sex offenders hold about them, the others and the world. Polaschek and Ward (2002) and Polaschek and Gannon (2004) postulates that there is five implicit theories amongst rapists: Women are Sexual objects; Male Sex Drive is Uncontrollable; Entitlement; Dangerous World; and Women are Dangerous. The current research examined whether the cognitive distortions of rapists are fully represent by the implicit theories proposed by Polaschek and colleagues. Semi-structured interviews were conducted with 21 convicted rapists and their cognitive distortions were analyzed using the grounded theory method. Our analysis indicates the presence of four of the five Polaschek’s implicit theories among our sample. In addition, the implicit theory Women are Sex object would better be conceptualise as Women are Object. Finally, and in contrast to Polaschek’s research, our sample of rapists demonstrated cognitions that normalize the use of criminality, delinquency, violence and sexuality to achieve their goals. These findings lead us to the creation of a new implicit theory : Normalisation of Crime. Our findings indicate that there may be implicit theories among rapists that have not yet been fully explored.

Keyphrases: Sexual aggression, Rapists, Implicit Theories, Cognitive distortions
Les déterminants biopsychosociaux de la réadaptation de travailleurs accidentés du travail

Despite years of research on chronic pain and disability, there is yet little consensus on a core set of risk factors. One thing that most agree on, is the fact that musculoskeletal disorders and the adjustment to its consequences is a complex, multidimensional process determined by biopsychosocial factors interacting with one another. Two articles are presented with the overall goal of identifying significant determinants of adjustment to musculoskeletal disorders. The first article is a systematic literature review that aimed at reviewing all pertinent biopsychosocial prognostic factors of adjustment to musculoskeletal disorders and assessed their relevance in predicting multidimensional outcomes, namely work participation, functional disability, pain, quality of life, psychological distress and recurrence. The 105 prospective studies identified and fitting the inclusion and exclusion criteria were analyzed and all significant associations were summarized. Then, 68 studies that included sociodemoraphic and biopsychosocial risk factors were separately analysed for their methodological quality, level of evidence (LOE) was established for each association between risk factors and outcome variables and existing differences were highlighted between phases of chronicity. Strong evidence was found for recovery expectations, coping, somatization, comorbidity, duration of episode, disability management and moderate evidence was found for pain behaviours. When it comes to predicting different outcomes reflecting the adjustment process of subjects with musculoskeletal disorders, each tends to have a different set of predictors. Few significant differences were found according to phases of chronicity. These results support the biopsychosocial nature of the adjustment to musculoskeletal disorders with a predominance of psychosocial determinants.   The second article is a prospective study with follow-ups at 2 and 8 months and was conducted on a sample of 62 mostly chronic occupationally injured workers receiving compensation benefits from the CSST (Quebec Workers’ Compensation Board). The study aimed to identify determinants of active involvement in a return to work process while adopting a biopsychosocial approach. It did so by investigating the pertinence of previously studied risk factors but for which no consensus yet exists, but also by investigating the pertinence of previously neglected or even omitted risk factors. After multivariate analysis, gender, work recovery expectations and importance of work were predictive of work outcomes at 2 months. After 8 months, age, medical consolidation, trauma symptoms, work support and importance of work predicted work outcomes. The results show the importance of approaching chronic work disability from a multidimensional perspective, although corroborating our literature review’s findings that psychosocial variables appear to be more significant predictors in this study.

Keyphrases: musculoskeletal disorders, chronic disability, prognostic factors, biopsychosocial, work outcome, systematic review, prospective study
Émiliano Renaud (1875-1932) : premier pianiste-virtuose du Québec : interprète-pédagogue-compositeur

Little is known of the career of composer and pianist Émiliano Renaud (1875-1932). Called the “Canadian Paderewski”, Renaud is the first Quebec virtuoso to have set up, as his Polish master, new standards in recitals, at a time when concerts mainly offered programs made of a mixture of excerpts rarely played by a single interpreter. Émiliano Renaud is also the first musician to have used the new technology of the radio for pedagogical purposes, as well as one of the few composers of the time to have had his works edited in the United States. Trained in Vienna and Berlin by renowned masters, he first pursued a teaching career at Indianapolis Music School before moving to New York for a few years, where he created a piano learning method. He moved permanently to Montreal in 1921 and was involved in numerous musical activities: giving recitals, composing, teaching and editing. This study, the first on the subject, traces the landmarks of Renaud’s career as a virtuoso at the beginning of the twentieth century. It offers a broad cultural and musical frame through which to assess the artist’s achievements.  One of the main aims of this research is to rehabilitate Émiliano Renaud, undeservedly cast into oblivion after his death. This rehabilitation is all the more necessary as Renaud contributed, in his own way, to developing Quebec’s musical life. In a related way, this study also tackles the issue of the reception of the phenomenon of virtuosity by the critics at that period. Annexes provide benchmarks, including a chronology, a list of the musician’s repertoire, and an inventory of his works.

Keyphrases: Émiliano Renaud, piano, radio, Émiliano Renaud, piano, virtuoso, Canadian music, Renaud-Phone Piano Method, radio
Inventaire analytique de l'émission radiophonique culturelle québécoise L'Heure provinciale à CKAC (1929-1939)

This thesis analyzes the content of a radio program funded by the Government of Quebec called L’Heure provinciale aired on CKAC Montreal between 1929 and 1939. This one hour program was broadcast twice per week over a ten-year period. It provided lectures and also artistic performances in the fields of music and theatre. According to the mandate given to its directors, Édouard Montpetit and Henri Letondal, the program aimed to educate listeners and to promote local artists in an entertaining atmosphere. The analysis of the contents aims at verifying whether the objectives of education, professionalization and emancipation were realized.

Keyphrases: Radio, L’Heure provinciale, CKAC, Radio broadcast
Relations entre le niveau de vie, la fécondité et les besoins non satisfaits en matière de planification familiale en Guinée

The goal of this thesis is to study the relationship between the married women standard of living, their fertility and their unmet need for family planning. The data used for the analysis have been taken from two individual demographic survey files (DHS) carried out in Guinea in 1999 and 2005. The standard of living is measured using a composite indicator established from the housing characteristics and some capital goods of the family.   We have adopted two strategies of analysis: Descriptive and Multivariate Analysis. Thus, we have studied the levels and tendencies of these two behaviors of fertility in the large cities, small or secondary cities, rural places, and at the national scale. Statistics appropriate methods of regression (Poisson regression method, logistic binary method and multinomial method).    The results of descriptive analysis have confirmed a weak fertility in women from rich classes in comparison with poor women and a reduction of their unmet need for family planning. The relationship which proved very statistically significant in 1995-1999 whichever the place of residence was not observed with the multivariate analysis method, after controlling some socioeconomic, demographic and cultural characteristics. In the multivariate analysis, the woman education and her behavior in terms of contraception were particularly important in her fecundity.    Moreover, the woman’s education, her age, parity (married status), her religion, the discussion of the couple about the family planning, the husband attitude concerning the family planning constitute some important factors of unmet need for family planning. The term of Interaction age group and number of living children turns out strongly significant, indicating that the parity (man-woman) effect can change according to the age group of the woman.      In fact, our analysis have shown with clearly that the negative relationship between the standard of living, the fertility and the unmet need is confirmed with various degrees according to the place of residence and the survey period.  The differences between the closely related groups are too weak.

Keyphrases: Standard of living, Unmet need for family planning, Guinea, Fertility
Développement et évaluation d'une intervention infirmière virtuelle sur mesure visant à faciliter l'autogestion de la douleur après une chirurgie cardiaque

Several studies have shown that many patients undergoing a cardiac surgery suffer from moderate to severe pain. These levels of pain may be explained by individual barriers toward pain relief. Knowledge acquired on pain-related cognitions has not been translated into new approaches. The aim of the doctoral project was 1) to develop an intervention to facilitate the self-management of postoperative pain after cardiac surgery and, 2) to assess its the acceptability and feasibility and to investigate its efficacy potential on pain relief in patients undergoing cardiac surgery.   The development of SOULAGE-TAVIE included four steps based on clinical, empirical and theoretical knowledge and inspired by diverse methodological considerations. SOULAGE-TAVIE consists in a 30-minute computer-tailored preoperative educational session about postoperative pain management, tailored according to an algorithm. Two short reinforcements are provided in person. The evaluation of SOULAGE-TAVIE consisted in a pilot randomized controlled trial including 60 participants assigned to the experimental group (EG: SOULAGE-TAVIE) and the control group (CG: usual care including educational pamphlet). Data were collected at the time of admission and across Day 1 to 7 after surgery.   The results provide preliminary support for the acceptability and feasibility of a tailored and virtual intervention. The results revealed that patients of the EG did not experience less intense pain but they reported significantly less pain interference when breathing/coughing, exhibited fewer pain-related barriers, and consumed more opioid medication. This pilot study provides promising results to support the potential benefits of this new web-tailored approach. Patient empowerment is complementary yet crucial in the current context of care and may contribute to improve pain relief.

Keyphrases: Postoperative pain, Cardiac surgery, Nursing, Educational intervention, Computer tailoring, Virtual, Pilot randomized controlled trial
La protection légale des connaissances traditionnelles des peuples autochtones Mapuches, par rapport à l’utilisation des organismes génétiquement modifiés (OGM) au Chili

Given the lack of economic resources and poverty, « GMOs » would appear to be a useful tool contributing to economic growth and food production, particularly in developing and underdeveloped countries. However, there is an equally important corollary issue we must address, namely the legal protection afforded by legislation both nationally and internationally, to « traditional knowledge » when they are faced with the use of GMOs. Understanding this interaction and its impact on culture is a significant issue at present, especially when one considers the importance of «local knowledge » as an element for the preservation of « biodiversity » and « sustainable development ».

Keyphrases: Autochtones Mapuches, Native Mapuche, Chile, Traditional knowledge, Democracy, Sustainable development, Genetically Modified Organisms, Cultural pluralism, Legal protection, Holistic vision
L’annonce d’un décès au service des urgences : une étude qualitative

We explored the competencies that Emergency Department (ED) healthcare providers (HPs), physicians and nurses working as team members with complementary roles, have developed through notifications of death, to inform the teaching of this ‘Communicator‘ competency. We used semi-structured interviews on a non-probabilistic sample of 8 HPs. We analyzed the interviews using recognized qualitative methods. The total self-estimated number of death notifications attended by our HPs is superior to 2000. Analysis showed that experienced HPs use a uniform structure to death notification in ED. In spite of this, the use of a protocol for notification was considered inappropriate because it was deemed too rigid. Flexibility and empathy emerged as essential qualities for HPs. We submit that the family‘s ED visit is an episode of disorganization/dysfunction that gets partially resolved during their stay. Based on our results, we propose an educational model for teaching delivery of news of death in the ED.

Keyphrases: Mort, Communication, Death, Bereavement, Bad news, Notification, Protocol, Competency, Emergency department, Physician-patient relations, Physician-family relations, Communication