NCube/papyrus huggingface dataset:
Plaidoyer pour une responsabilité intégrée de l'ONU : le cas des opérations de paix

It is with great complexity and ambiguity that the United Nations Peace Operations took place on the international scene during the last decade. Since their deployment reflects first and foremost one of the most fundamental goal of the Unites Nations Organization, namely: to maintain international peace and security (Section 1(1) of the Charter of the United Nations), it is predictable that the actions they undertake on the field may produce harmful effects for the third parties. The question raised by this thesis aims to discover if and to what extent the UN responsibility is governed by International Law when such third parties suffer from material and personal damages at the hand of UN Peace Operations troops. What does International Law provide? Are there any means of reparation for the victims? Searching for the UN responsibility includes the supposition that the Organization possesses the international legal personality, because its legal existence represents the basic postulate on which its responsibility will be based. The Advisory Opinion of 11 April 1949 of the International Court of Justice on Reparation for Injuries Suffered in the Service of the United Nations constitutes the exact moment of the personification of the UN on the international scene. From a more substantial perspective, the outlines of the UN responsibility in the peacekeeping context are being drawn around one crucial element: « the internationally wrongful act ». This element includes two parts; on the one hand, an objective component which consists of a specific conduct (action or omission) breaching an international obligation; and, on the other hand, a subjective component attributing to the Organization the breach of this international obligation. This framework of the UN responsibility will allow a better understanding of the extent to which the responsibility of the Organization can be retained for actions or omissions committed in a peacekeeping context. More importantly, it allows us to plead for a responsibility which encompasses not only the endogenous characteristics of each situation, but also a legal protection by International Law of the interest of each individual.

Keyphrases: Droit international public, Public International Law, International responsibility, United Nations, Peace Operations, International personality, Advisory Opinion of 11 April 1949 of the International Court of Justice on Reparation for Injuries Suffered in the Service of the United Nations, Internationally wrongful act, International Law Commission, Peacekeeping
La communication des résultats de recherche en génétique : réflexion sur le point de vue de parents d'enfants souffrant d'autisme

Genetics studies are becoming increasingly prevalent leading to a growing body of information on disease susceptibility with the potential to improve health care. Many of these results are considered exploratory with no clinical utility. Official guidelines in ethics, advocating a disclosure of global results, also tend increasingly towards the communication of individual results when available and applicable if the research participant choose so. An "ethical imperative" to return research results is increasingly acknowledged in research ethics guidelines. This emerging moral duty raises many questions including the issue of whether and how research participants might receive their individual results. In this study, we explore the perspectives of parents of an autistic child participating in genetic research. It is essential and important to explore their needs and expectations about how they would like to be delivered research results. The purpose of this study is to propose an ethical reflexion on providing individual genetic research results to participants: is there a duty ? a right ? Providing individual genetic research results to participants is a key challenge. We expect to find major challenges in matters of return of result given both the high expectations surrounding genetic research and the vulnerable state of some patients/research participants.

Keyphrases: Research results, Disclosing, Research participants, Research ethics, Genetics
L’étude du rôle d’ARF1 dans la migration et la prolifération des cellules du cancer du sein

The ADP-ribosylation factors (ARFs) are small GTPases involved in vesicular transport, lipids synthesis and cytoskeleton remodelling. The isoforms 1 (ARF1) and 6 (ARF6) are the most studied. ARF1 is classically distributed at the Golgi apparatus whereas ARF6 is found at the plasma membrane and onto recycling endosomes. It was recently demonstrated that ARF6 is highly expressed and activated in several breast cancer cell lines and is associated with enhanced migration and invasiveness. However, the role of ARF1, in these biologicals processes necessary for metastasis formation, remains unclear. In this study, we used MDA-MB-231 cells, an invasive breast cancer cell line, that expressed high levels of EGFR (Epidermal Growth Factor Receptor) to investigate the role of ARF1 in migration and proliferation. To further establish the role of ARF1 in cell migration, EMT and proliferation, we used two experimental approaches. First, we decreased endogenous ARF1 expression by RNA interference and second we overexpressed the dominant negative (ARF1T31N) and constitutively active (ARF1Q71L) ARF1 mutants, which mimick the inactive and active forms of ARF1, respectively. We demonstrated that depletion of ARF1 as well as overexpression of the inactive form of ARF1 blocked EGFR-mediated cell migration and proliferation by inhibiting the activation of PI3Kinase. Moreover, we showed, using invasive and non invasive breast cancer cell lines, that ARF1 and both Cytohesin-1 and Cytohesin-2 are required for invasivness. Using similar approaches, we reported that inactivation of ARF1 in MDA-MB-231 cells promotes cell growth arrest associated to senescence program by regulating the function of the Retinoblastoma protein pRb. Altogether, these findings demonstrate a physiological role for ARF1 in cell migration and proliferation. These two biologicals events are necessary for breast cancer progression.

Keyphrases: ARF1, cell proliferation, EGFR, PI3Kinase, pRb, migration, Cytohesin-1, Cytohesin-2, cell migration
Phylogénomique des Archées

Horizontal gene transfer (HGT) had been demonstrated to play an important role in the evolution of prokaryotes. Their impact on phylogeny was the subject of a heated debate, with some proposing that the concept of a species tree should be abandoned. The phylogeny of prokaryotes does contain a major part of the historical signal, because stable and functional horizontal transmissions appear to be by far rarer than vertical transmissions (tens versus billions). However, the cumulative effect of HGT is non-negligible and can potentially affect phylogenetic inference. Therefore, most researchers base their phylogenetic inference on a low number of rarely transferred genes such as ribosomal proteins, but they assume the selection of the model of evolution as less important, this despite the fact that it has been shown of prime importance for much less deep divergences, e.g. like animals. Here, we used a combination of simulations and of real data from Archaea to study the relative impact of HGT and of the inference methods on the phylogenetic accuracy. Our simulations prove that (1) HGTs have a limited impact on phylogeny, assuming a realistic rate and (2) the supermatrix is much more accurate than the supertree approach. We also observed that more complex models of evolution not only have a better fit to the data, but can also have a direct impact on different phylogenetic groups and on the robustness of the tree. Our results are in contradiction to a recent publication proposing that the Thaumarchaeota are at the base of the Archaeal tree.

Keyphrases: phylogeny, phylogenomics, prokaryotes, Archaea, horizontal gene transfer, molecular evolution, simulations, simulation, evolutionary models, supermatrix, supertree
Vestiges industriels montréalais : appropriations, rôles et enjeux sociaux

The notion of heritage, formerly attached to concepts such as art and monument, seems to these past years emancipate itself from its traditional material forms to include more and more intangible manifestations. Authors (Smith 2005; Graham, Ashworth et Turnbridge 2000) wanting to rethink the shaping of the notion have even suggested to conceive heritage as a cultural active process that would be a product of its environment and would be mainly constituted of actions, such as remembering, transmission of memory and knowledge, definition of identity and social cohesion, all undergoing in the present and being continuously actualized. This dissertation proposes the theoretical exercise of applying this new active conception of heritage to the study of the role that industrial remnants, a sort of heritage often discarded, plays in Montreal’s society. The adoption of a new definition of the notion of industrial heritage that withstands the idea that the tangible can only be understood and interpreted by the intangible allows the study of social and cultural practices, like urban exploration, ruin photography and artistic installations, who attest of the values and significations that a part of the population associates with industrial ruins. This work will also tackle the more orthodox usages of industrial remnants, such as conversions or patrimonial preservations, to see if those can also be included in a performative concept of industrial heritage. This study on the conventional and non conventional usages of industrial ruins wishes to contribute to the reflection on modes of experiencing and sharing industrial heritage that could comply with the values and significations that are assigned to these remnants.

Keyphrases: Heritage, Industrial archaeology, Montreal, Social practices, Identity
Ontogénèse et spécificité de la voix humaine

Voice is a very prominent auditory stimulus in our acoustic environment. It is not only the carrier of speech, but would also be an auditory face that conveys important affective and identity information. Our ability to discriminate and recognize voices is socially and biologically important as it is amongst the most important functions of the human auditory system. This thesis was interested in the ontogenesis and specificity of the cortical response to human voice and had three objectives: (1) to develop an electrophysiological protocol to objectively measure the processing of voice familiarity in adult subjects; (2) to assess whether the same electrophysiological protocol could also objectify preferential processing of a familiar voice in 24-hour-old newborns, in particular the mother’s voice; and (3) to test the robustness of an electrophysiological measure, more specifically the Fronto-Temporal Positivity to Voices, interested in pre-attentional discrimination between vocal and non-vocal stimuli. Results from these three experimental designs have enabled (1) to identify electrophysiological components (Mismatch Negativity and P3a) sensitive to the processing of voice familiarity; (2) to highlight a singular pattern of cortical activation to the mother’s voice in newborns, providing the first neurophysiological evidence of language acquisition, a process especially related to the mother-child interaction; and (3) to confirm that vocal/non-vocal discrimination is a pre-attentional process, while enhancing the selectivity and the specificity of voice processing cortical response.

Keyphrases: discrimination, N1, MMN, P3a, voice, familiarity, discrimination, electrophysiology, N1, MMN, P3a, source analysis, newborns
Les liens entre le statut parental et les infanticides des enfants de douze ans et moins

Infanticide is considered as being an important part of infantile mortality. In this study, infanticide is studied according to the parental status (biological parent versus non biological parent), method of death and differential rates of suicide. The first hypothesis proposed that there should be an over-representation of the non biological parents in the homicide cases with the children of less than twelve years and this in look of the population rates. The second hypothesis proposed that the murders of the biological parents should clothe a more final character (weapon usage to fire, poisoning) that the homicides of the non biological parents that should be principally characterized by bad treatments. Other hypotheses are examined according to the rates of suicide and of the sex of the aggressor. The present study is based on the cases of homicides of child under the age of twelve on the territory of the Quebec from 1990 to 2007 (N = 182). The results support partially the hypothesis 1 and confirm the hypothesis 2.  In this direction, the results of this study come to support the evolutionist hypotheses that principally are based on the theory of the parental investment. Implications of the obtained results are discussed.

Keyphrases: Infanticide, Homicide, Infanticide, Discriminative parental sollicitude, Parental investment, Step-parents, Evolutionary thinking, Homicide
Élaboration d'une grille permettant l'analyse de la qualité de situations d'apprentissage et d'évaluation en lecture auprès d'élèves du parcours de formation axée sur l'emploi

This research project involved the development of an assessment tool for secondary teachers.  The objective of the project was to design and validate, with a group of experts, a rubric for analyzing the quality of Learning and Evaluation Situations (LESs) for students with learning difficulties—notably, those in the Work Oriented Training Path (WOTP).  This research was designed to support WOTP teachers’ efforts to develop competency-based instruction. The LES is a powerful context for teaching and learning, but remains underutilized.  The rubric’s conceptual framework, based on Legendre’s (2005) model of situated learning, facilitates (a) identification of the key features of LESs, and (b) analysis of their quality. Roque, Langevin and Riopel’s 1998 methodology—‘l’Analyse de la valeur pédagigique’ (AVP)—was used to analyze the effectiveness of the rubric for its intended users (i.e., WOTP teachers).  This research project’s contribution to the field of education lies in its practicality.  The rubric provides teachers with ready access to a reference bank of explanations/examples of key LES features, encouraging reflection regarding the quality of LESs they design.

Keyphrases: Rubric, Learning and Evaluation Situation, LES, Reading, Work Oriented Training Path, WOTP
Recuperación de la memoria histórica en la obra teatral de 
José Sanchis Sinisterra ¡Ay, Carmela!

This MA thesis embodies a research undertaken relative to the play ¡Ay, Carmela !, written by José Sanchis Sinisterra, a Spanish playwright and theatrical director. Staged for the first time in 1987, ¡Ay, Carmela ! is considered one of the most important dramas created since the post-war era. This work, which gained international recognition, perfectly illustrates the consequences of the Spanish Civil War (1936-1939). By examining both time and space, as well as analyzing the characters of this play, the present research intends to prove that the manifestations through which historical memory is recuperated throughout the play ultimately transform it into the forerunner to the “Historical Memory Law” (Ley 52/2007, also known as the “Declaración de reparación y reconocimiento personal”).  Moreover, this thorough examination of the play will demonstrate within it a strong critique of the Pact of Silence signed during the Democratic Transition (1975-1978).  Two main methodological approaches will be used to do so: that of theatre semiotics (specifically the theories of Bobes, García Barrientos, Rubiera) as well as comparisons to the writings of P. Ricœur y de J. Derrida, which will help support the ideas related to the memory, the forgetting and the forgiveness. Finally, this Master’s thesis will end with a short comparative study between the aforementioned play and the movie ¡Ay, Carmela!, directed by Carlos Saura.

Keyphrases: Carlos Saura, Spanish civil war, Pact of silence, Memory and historical reconciliation, Contemporary spanish theater, Carlos Saura
Relevé et analyse spectroscopiques d'étoiles naines blanches brillantes et riches en hydrogène

We present a spectroscopic survey and analysis of over 1300 bright (V < 17.5), hydrogen-rich white dwarfs. High signal-to-noise ratio optical spectra were obtained and are then analyzed using our standard spectroscopic technique which compares the observed Balmer line profiles to synthetic spectra computed from the latest generation of model atmospheres. First, we present a detailed analysis 29 DAO white dwarfs using our new up-to-date model atmosphere grids in which we have included carbon, nitrogen, and oxygen at solar abundances. We demonstrate that the inclusion of these metals in the model atmospheres is essential in overcoming the Balmer-line problem, which manifests itself as an inability to fit all the Balmer lines simultaneously with consistent atmospheric parameters. We also identify 18 hot DA white dwarfs that also suffer from the Balmer-line problem. Far ultraviolet spectra from the {\it FUSE} archive are then examined to demonstrate that there exists a correlation between higher metallic abundances and instances of the Balmer-line problem. The implications of these findings for all hot, hydrogen-rich white dwarfs are discussed. Specifically, the possible evolutionary scenario for DAO white dwarfs is revised and post-EHB evolution need no longer be invoked to explain the evolution for the majority of the DAO stars. Finally, we discuss how the presence of metals might drive a weak stellar wind which in turn could explain the presence of helium in DAO white dwarfs. We then present the complete results from our survey, including the spectroscopic analysis of over 1200 DA white dwarfs. First we present the spectroscopic content of our sample which includes many misclassifications as well as several DAB, DAZ and magnetic white dwarfs. We then discuss the new model atmospheres we employ in our analysis. In addition, we use M dwarf templates to obtain better estimates of the atmospheric parameters for those white dwarfs which are in DA+dM binary systems. A handful of unique white dwarfs and double-degenerate binary systems are also analyzed in greater detail. We then examine the global properties of our sample including the mass distribution and mass distribution as a function of temperature. Next, we look at how the new Balmer-line profiles affect the determination of the atmospheric parameters. We then proceed to test the accuracy and robustness of our method by comparing our results to those of the SPY survey which has analyzed over 300 of the same white dwarfs in a completely independent manner. Finally, we also re-visit the ZZ Ceti instability strip and how the determination of its empirical boundaries is affected by the latest line profile calculations.

Keyphrases: Stars: abundances, Stars: atmospheres, Stars: evolution, Stars: fundamental parameters, White dwarfs
Fertility differentials of Jewish women living in Israel and the West Bank

Israel is one of the most fertile developed countries in the world and has had a stable fertility rate since 1995. The country avoided the dramatic fall in fertility that has been observed in most Western countries. The fertility rate was of 2.96 children per woman in 2009 (Statistical Abstract of Israel, 2010, table 3.14). Maintaining such a high fertility level could be due to immigration and the “demographic war” between the different communities living in the country (Sardon, 2006). However, a significant difference between the levels of fertility of the jewish population of Israel and the West Bank has been observed for several years. In the literature, studies of fertility in Israel are conducted at a national level, which neither reveals nor explains the difference. Accordingly, Israel’s high fertility deserves a particular attention. This project aims to identify the different factors that affect the fertility of Jewish women living in Israel and in the West Bank. It will contribute to a better understanding of the fertility behavior of the Jewish population of the West Bank and may shed light on the complex mechanisms that govern the relations between Jews and Arabs in the Occupied Territories. With data collected in the General Social Survey of Israel of 2004, descriptive and explanatory analyses were produced. In the first part, factors influencing fertility in each region have been determined and an analysis of the importance of each factor on fertility was conducted in the second part. The outcome of interest is the number of children ever born to women aged 20 to 55 and the independent variables are: religiosity, education, monthly family income, employment status, country of origin, age and marital status. This study showed that Jewish women residing in the West Bank have an expected number of children 13% higher than their counterparts residing in Israel. It is also shown that the intensity of religious interest plays an important role in explaining the high fertility of Jewish women in both regions but its impact is more important in Israel. Education also plays an important role in reducing the expected number of children, especially in the West Bank. All of these factors contribute to explaining the different fertility levels in the two regions but the study shows that these factors do not provide an exhaustive explanation of higher fertility in the West Bank. There must be other forces that have an impact on fertility but which are not measurable such as nationalism or secularization, for example.

Keyphrases: Fertility differentials, Israel, West Bank, Religiosity
Comment comprendre les transformations du mouvement des femmes au Québec? : analyse des répercussions de l’antiféminisme

The women’s movement in Quebec has known significant transformations during the last decades. Several causes have been put forward to explain these changes, such as globalization, neoliberalism or internal causes. In the 1980s, there has been a backlash against the women’s movement in the province of Quebec and a specific form of anti-feminism emerged, masculinism. This backlash has changed the context in which the women’s movement has evolved. The objective of this thesis is to analyze the impact of anti-feminism on the transformations of the women’s movement.  In order to analyze the interactions between the women’s movement and anti-feminism, we study the anti-feminist discourse in the media from 1985 to 2009. First, we analyze the masculinist’s thematics contained in the newspapers La Presse and Le Soleil during this period. Second, we analyze various publications (annual reports, la Petite Presse and le Féminisme en bref) of the Fédération des femmes du Québec in order to see if the women’s movement has changed its analysis, strategies and actions in response to this backlash. Finally, using the theory of resource mobilization and the countermovements’ approach, we study the interactions between the women’s movement and masculinism. We come to the conclusion that there are interactions between the women’s movement and the countermovement (anti-feminism). Furthermore, we see that the emergence of anti-feminism has changed the analysis, strategies and actions of the women’s movement in response to this backlash.

Keyphrases: Féminisme, Fédération des femmes du Québec, Québec, Women's movement, Feminism, Anti-feminism, Masculinism, Media, Social movements, Countermovements, La Presse, Le Soleil