NCube/papyrus huggingface dataset:
Le respect du droit à la santé : analyse à partir du droit international de la personne et d'une comparaison entre les constitutions du Canada et du Brésil

The right to health is a well-established right in International Law. Many international treaties such as the International Covenant on Economic, Social and Cultural Rights (ICESCR) and the Constitution of the World Health Organization, create a legal obligation on States who have ratified these instruments to protect and ensure the right to health. This thesis aims to examine the right to health in the international law and its application in domestic law by the Constitutions of Canada and Brazil. The first chapter of this thesis explores the meaning, the scope and the limits of the right to health in the international legal order. In the second chapter, we analyze the national Constitution of these two countries. We have concluded that the Canadian Constitution does not explicitly address the right to health. However, articles 7 and 15 of the Canadian Charter of Rights and Freedoms, which ensure the right to life as well as the right to liberty and to non-discrimination, allow for the interpretation of the courts to guarantee the right to health. On the contrary, the Brazilian Constitution of 1988 has dedicated a whole section to Economics, Social and Cultural rights. Among these rights, the right to health is a very important right in the Brazilian Constitution as articles 196 to 200 ensure the right to health. Finally, through the case analysis of Canada and Brazil, this thesis shows that a constitutional provision on the right to health demonstrates a commitment on the part of the State to fulfill its obligations with respect to the international right to health. However, other strategies to implement this right can also be considered by the States, such as the use of international legal instruments as a source of interpretation.

Keyphrases: Canada, Right to health, International law, Human rights, Canada, Brazil
Dans les interstices du droit formel : responsabilité sociale des entreprises, soft law et gouvernance contractuelle de la chaine d’approvisionnement mondiale

Destined, in essence, to regulate interstate relations, public international law seems closed to the idea of recognizing liability of transnational corporations. However, this imperviousness to recognizing legal responsibility per se of global economic powers has not prevented a soft evolution of the international order. Following several scandals related to violations of human rights, some in the context of global supply chains, civil society could no longer allow transnational companies to take advantage of the existing legal vacuum. As a result, a global regulation strongly influenced by the trend of corporate social responsibility (CSR) emerged from a normative muddle. This institutionalization of CSR is based on several instruments, including guiding principles on Business and Human Rights which occupy a central position in this regulatory trend. It is intended that these principles will apply as a uniform, global normative canvas. Therefore, they should guide actions of companies regardless of their geographic location. The implementation of this CSR global framework is possible due to substantial pressure exerted by non-governmental actors, such as civil society and the market. These actors seek to promote CSR and facilitate the transformation of this regulation. Particularly, private standards are playing an increasingly important role in the governance of global supply chains. By establishing CSR in contractual relations, this governance would mark the advent of new regulatory tools which seek to fill in the public law gaps.

Keyphrases: Regulation globale, Public international law, Global regulation, Corporate social responsibility, Global civil society, Socially responsible investment, Transnational corporations, Governance, Global supply chain, Private norms
Analyse de la variabilité de la fréquence cardiaque chez les femmes enceintes atteintes d'apnée obstructive du sommeil

Purpose: Sleep breathing disorders are common during pregnancy and are associated with adverse consequences for the health of the mother and the fetus. These can be caused by changes in sympatho-vagal balance (SVB), which can be estimated through heart rate variability (HRV) analyses. The aim of the study is to assess the HRV in pregnant women with obstructive sleep apnea (OSA) at three time points. Methods: Seventeen pregnant women diagnosed with mild to moderate OSA performed 3 polysomnographic recordings (PSG): in the second trimester (PSG1), in the third trimester treated with a titrated oral appliance (OA) (PSG2) and 3-6 months post-partum. Data were analyzed in cumulative 5 minutes baseline interval samples (Baseline) and in cumulative 3 minutes interval samples before the onset of the OSA events (Event) for each sleep stages (NREM2, NREM3, REM) over the course of the night. Results: SVB (Low-/High-Frequency power ratio) was statistically significant for all cumulative PSGs per samples (Baseline sleep stages p < 0.01 and Event sleep stages p < 0.01 ; REM > NREM2 > NREM3). Significant diminution of apnea-hypopnea index (AHI) was observed at PSG2 (PSG1 vs PSG2; p < 0,01). In post hoc analysis, at PSG2 only, Event parasympathetic activity (Normalized High-Frequency % (Normalized HF %)) decreases significantly in NREM2 (p = 0.01) and NREM3 (p < 0.01) when compared to respective Baseline Normalized HF %. Conclusions: Results suggest normal shifts in SVB across sleep stages. Although AHI is reduced with the treatment of OA during pregnancy, the influence of the autonomic nervous system on respiratory events seems to remain mild.

Keyphrases: Heart rate variability, Obstructive sleep apnea, Pregnancy, Oral appliance
Effet du changement climatique et de la phénologie de l’arbre hôte sur l’étendue spatiale des épidémies de la tordeuse des bourgeons de l’épinette : une approche à base d’agents

Climate change continues to affect forest landscape dynamics at a global scale. However, it remains uncertain how these changes will affect future forests and in particular outbreaks of forest insect pests. Climate change can affect outbreaking insects by disrupting phenological synchrony between herbivorous insects and their host trees. Such disruptions can have important consequences for outbreak timing, extent, and severity. This study aims to understand how climate change could affect the phenological synchrony between the spruce budworm (Choristoneura fumiferana), a native outbreaking defoliator, and its host trees (Abies balsamea and Picea mariana), and how this might affect the extent of spruce budworm outbreaks in the Côte-Nord region in Quebec, Canada. We explored the effects of two experimental factors on outbreak extent using a spatially explicit stochastic agent-based simulation model (ABM): (1) daily temperature represented as two levels of increase (+2°C and +4 °C) relative to a 2016 baseline, and (2) variation in host phenology represented as four different levels of uncertainty (SD) around the timing of budburst. We assessed how these factors affected variation in spruce budworm outbreak extent and outbreak patch spatial complexity over a 20-year simulation horizon. Our simulation results indicate that host trees-insect phenological synchrony is strongly affected by temperature changes, but in a non-linear way. An increase of 2°C was found to reduce outbreak extent due to poor larval survival, while an increase of 4°C resulted in higher insect survival and larger outbreaks. Our model can help to forecast future forest dynamics and facilitate the development of better management strategies to reduce the effect of outbreaks on forest landscapes.

Keyphrases: Choristoneura fumiferana, Abies balsamea, Picea mariana, Complex systems, Agent-based modelling, Climate change, Phenological synchrony, Phenology
Le cycle du mercure dans les sédiments de la rivière Saint-Maurice impacté par des perturbations du paysage : hydroélectricité, feu de forêt et coupes forestières

Run-of-river dams (RoRs) are expected to triple in the next decade in response to the global transition to renewable energy. However, unlike reservoir dams whose impacts on the mercury (Hg) cycle are well known, very few studies have evaluated the impact of RoRs on the mobilization and transformation of Hg into methylmercury (MeHg), a bioaccumulative and bioamplifiable neurotoxin along the trophic chain. Despite the limited area of flooding created by these small structures compared to reservoir dams, the pondages created upstream could still contribute to creating conditions conducive to the methylation of Hg. This study was carried out on the St. Maurice River (QC, Canada) located in a riverscape recently influenced by to the recent construction of two RoRs and artificial wetlands and to the concomitant presence of disturbances in the landscape. The results show an increase in the percentage of methylmercury (% MeHg) from 2 to 3 times in the flooded areas compared to the reference sites or downstream sites. In addition, an increase in total mercury (THg) and organic matter (MO) concentrations are observed in these same flooded areas subject to landscape disturbances: forest fire and logging. It suggests that forest fires and logging are contributing to the transfer of MO bound to Hg from the watershed to the river, as indicated by the positive correlation between the C / N ratio and % MeHg. The accumulation of MO and Hg in the pondages are likely favorable to the stimulation of the prokaryotic methylating community whose hgcA marker gene was detected at all sites with a very diverse composition, dominated by methanogens, sulfate-reducers and fermenters in this system. In the light of these results, we suggest that future studies on RoRs integrate the landscape as a whole and establish a monitoring of Hg concentrations before, during and after construction.

Keyphrases: hgcA, Mercury, Methylmercury, River, Landscape, Run-of-river dam, Organic matter
L’influence de l’utilisation du territoire et des structures géomorphologiques sur la rétention d’azote, de phosphore et de carbone des ruisseaux

Streams are important sites of elemental transformations due to the relatively high contact rates between flowing water and biogeochemically reactive sediments. Increased urbanization typically results in higher nutrient and carbon (C) inputs to streams from their watersheds and increased flow rates due to modification in channel form, reducing within stream net retention and increasing downstream exports. However, less is known on how moderate urbanization might influence the joint processing of C, nitrogen (N), and phosphorus (P) in streams or the relative influence of changes in watershed and stream features on their fluxes. In this study, we performed mass-balances of different C, N, and P species in multiple reaches with contrasting land use land cover and geomorphic features (pools, riffles, runs) to determine the effects of geomorphology versus human influence on elemental fluxes in a pristine and a semi-urban stream. N was the most responsive of all elements, where nitrate concentrations were 3.5-fold higher in the peri-urban stream. Dissolved organic carbon was only slightly higher in the peri-urban site whereas total P not significantly different between streams. In terms of fluxes, nitrate behaved differently between the streams with net retention occurring in the majority of the reaches of the pristine site, whereas net export was observed in all of the reaches of the semi-urban one. We found a decrease in nitrate concentrations with an increase in excess deuterium of the water (d-excess), an indicator of how overall water retention capacity of the watershed favored N loss. Within the stream, the presence of pools, and reduced channel slope, which also increase water retention time, again favored N loss. Overall, nitrate was the most sensitive nutrient to slight urbanization, where higher export to stream was influenced by land use, but where geomorphic features were more important in driving retention capacity.

Keyphrases: Streams, Nitrogen, Phosphorus, Carbon, Retention, Land use, Urbanization, Geomorphic structures
Presence, severity, and course of psychological distress in men and women with and without coronary artery disease : psychological status in patients differs as a function of time, sex, and/or coronary artery disease status

Psychological distress is more prevalent and severe among patients with coronary artery disease (CAD) compared to healthy individuals. Little is known regarding its time course, and whether these differences extend to individuals with non-cardiovascular (CV) illnesses. Objective: This study examined the presence, severity, and time course of psychological distress in men and women with CAD and those of similarly aged individuals suffering from non-CV conditions. Methods: 1294 individuals (61% men; meanage = 60.4 ± 7.0 years) with stable CAD or non-CV illnesses reported on social support, hostility, stress, anxiety and depression at baseline as well as 4.8 ± 0.8 years later. Analyses involved mixed (Sex*CAD status*Time) repeated measures analyses (controlling for relevant covariates), as well as Chisquare and McNemar analyses. Results: Women with CAD reported more symptoms of depression compared to other participants at both evaluations (p’s<0.01), and reported more symptoms of anxiety and stress compared to others at T1 (p’s <0.05). At T2, perceived stress remained significantly greater among women with CAD compared to men (p’s<0.01), though differences in anxiety were no longer significant. Men reported more hostility than women (p=0.001). CAD women fell within the clinical range for depression (p<0.001), anxiety (p=0.001), and stress (p=0.030) more frequently compared to others at T1, and for depression (p=0.009) and stress (p=0.002) at T2. Conclusions: The evolution of patient distress differed as a function of the measure examined, their sex, and/or CV status. While psychological distress was prevalent among these patients with diverse health conditions, women with CAD were particularly and chronically vulnerable.

Keyphrases: Psychological distress, Coronary artery disease, Depressive symptoms, Anxiety symptoms, Stress symptoms, Chronic illness
Association entre la dépression et le biais d'attribution hostile chez les individus hostiles et non hostiles : une étude de potentiels reliés aux événements

Background: Hostility and aggression have been found to be highly prevalent among depressed  patients and are associated with higher comorbidity and illness severity levels. Although  negative interpretation biases are a fundamental element of cognitive models of depression, few  studies have examined the specific biases in information processing, mainly the hostile  attribution bias, found in hostile individuals who present depressive symptoms. Method: Using  pre-collected data from a sample of 72 (male=41,6%, female=58,3%) undergraduate and  community-based hostile (n=26) and non-hostile (n=46) adult participants, the authors aimed to  examine the association between depression and the hostile attribution bias by determining  whether depression level scores were uniquely related to electrophysiological measures of the  hostile attribution bias. Results: The hostile group showed higher measured levels of depression  and reactive aggression, compared to the non-hostile group. Also, depression scores were  significant predictors of the N400 effect in the non-hostile condition, while reactive aggression  was not, whereas in the hostile condition, the overall model was significant, with depression and  reactive aggression levels both showing strong trends towards significance. Limitations: A small  sample size limited the scope of our conclusions. Also, sample selection prevented the authors  from examining specific group differences regarding the hostile attribution bias in depressed and  non-depressed groups. Conclusion: This study highlights the importance of better understanding  the perception mechanisms that are associated with depression and to consider the application of  cognitive restructuring techniques to counter biased interpretation processes in settings where  depression and aggression intersect. This study also suggests that alternatives to self-evaluative  methodologies might be more useful when assessing automatic and implicit processes.

Keyphrases: N400, Aggression, Hostile attribution bias, ERP
Exploration de l’expérience du deuil parental : une étude rétrospective auprès de parents dont l’enfant est décédé d’un cancer au CHU Sainte-Justine

Objectives: For parents, grieving the loss of a child from cancer is a complex and painful journey for which we do not understand all the issues, in particular, what influences psychological health and long-term quality of life and more specifically the situation of fathers. This study was conducted with parents two to twenty years after the death of their child. The objectives are 1/ to describe the quality of life, psychological distress, and bereavement symptoms of bereaved parents, 2/ to explore the influence of gender and time since death on psychological health test results, and 3/ to identify predictors of parents' current psychological health. Methods: A retrospective quantitative analysis carried out was conducted with 32 mothers and 14 fathers of children who died of cancer at Sainte-Justine UHC between 2000 and 2016 were recruited and completed a self-reported online questionnaire using Medical Outcomes Study Short Form (SF-12), Brief Symptom Inventory (BSI-18) and Inventory of Complicated Grief (ICG-19). Results: Parents’ symptoms of grief continue to be very present, even up to 18 years after death (58%). Mostly mothers recall very significant symptoms of grief. They report a significant change between the first year after death and now which is less true for fathers. Finally, the predictors of Quality of Life and distress provide us with information on vulnerability patterns: being a father, having high symptoms of grief, and short time elapsed since death. Conclusion: Understanding the differences between fathers’ and mothers’ grief is important for health professionals to better support both bereaved parents efficiently. The results suggest that a follow-up of bereaved parents is needed, even long after the death of their child.

Keyphrases: Deuil parental, Pediatric cancer, Quality of life, Psychological distress, Grief symptoms, Retrospective analysis
L’utilisation de la technologie mobile pour réduire les comportements d’autostimulation chez les enfants ayant un trouble du spectre de l’autisme

Many children with ASD engage in stereotypy, which may interfere with learning, socialization as well as adaptive functioning. Although behavioral interventions have been known to effectively reduce stereotypy in children with ASD, these types of interventions are not accessible to all families. In response to this issue, the purpose of our study was to evaluate the effects of the iSTIM, an iOS application designed to support parents in the reduction of stereotypy in their child with ASD. We used a series of AB designs to determine the effectiveness of iSTIM on stereotypy and appropriate behavior in seven families. The use of iSTIM by the parents led to a reduction in stereotypy for six of our seven participants as well as an increase in an alternative appropriate behavior in their three children. Our results indicate that the use of technology may be a cost effective and easily accessible method for parents to reduce stereotypy in children with ASD.

Keyphrases: Formation des parents, Behavioral interventions, Parent training, Stereotypy, Technology
Algèbres de Temperley-Lieb, Birman-Murakami-Wenzl et Askey-Wilson, et autres centralisateurs de U_q(sl_2)

This master thesis contains three articles related by the underlying idea of a generalization of the Schur-Weyl duality. The main objective is to obtain an algebraic description of the centralizer of the image of the diagonal action of U_q(sl_2) in the tensor product of three irreducible representations, when q is not a root of unity. The connection between a centrally extended Askey-Wilson algebra AW(3) and this centralizer is examined for this purpose. In the first article, the elements of the centralizer of the action of U_q(sl_2) in its threefold tensor product are defined with the help of the universal R-matrix of U_q(sl_2). These elements are shown to satisfy the defining relations of AW(3). In the second article, the universal R-matrix of the Lie superalgebra osp(1|2) is used in a similar fashion with the Bannai-Ito algebra BI(3). In this case, the formalism of the R-matrix allows to define the higher rank Bannai-Ito algebra BI(n) as the centralizer of the action of osp(1|2) in its n-fold tensor product. The third article proposes a conjecture that establishes an isomorphism between a quotient of AW(3) and the centralizer of the image of the diagonal action of U_q(sl_2) in the tensor product of any three irreducible representations. The conjecture is proved for several cases, and the Temperley-Lieb, Birman-Murakami-Wenzl and one-boundary Temperley-Lieb algebras are recovered as quotients of the Askey-Wilson algebra.

Keyphrases: Askey-Wilson algebra, Quantum algebra U_q(sl_2), Temperley-Lieb algebra, Birman-Murakami-Wenzl algebra, Centralizers, Representations, Schur-Weyl duality, Universal R-matrix, Bannai-Ito algebra, Lie superalgebra osp(1|2)
Contraintes sur les diquarks scalaires à partir des processus à haute énergie

The Standard Model of particle physics explains with great success how fundamental particles interact. However, this model cannot explain some contemporary challenges of the domain, such as the large number of free parameters, the hierarchy problem or the identity of dark matter. To explain these phenomena, we need to search for physics beyond the Standard Model. In order to satisfy the existing constraints from experimental measurements, we can consider the addition of a single new particle to the Standard Model that couples to two quarks, a diquark. Its contribution to hadronic processes offers an opportunity to set limits on its parameters from contemporary experimental data. This would allow us to evaluate their potential and identify processes to which they can contribute. Among the possible diquark states, we find the scalar diquarks Dᵘ and Dᵈ, which have an antisymmetric coupling to pairs of right-handed up-type or down-type quarks, respectively. To obtain constraints on their mass Mᴰ and on their couplings to quarks (x^q, y^q), where q = u, d, is the main goal of this work. In order to do so, we start by considering direct searches in the production of dijet, the experimental signature of the decay of these particles. Afterwards, we probe the indirect influence of the Dᵘ diquark to the experimental measurements of the single-top-production cross section. Recent data for both of these processes from the Large Hadron Collider (LHC) is used to compare the theoretical predictions of these models and quantify their viability by providing new constraints on its parameters. We are able to improve the constraints found in the literature from |xᵘ| ≤ 14.4 to |xᵘ| ≤ 0.13–0.15 for Dᵘ and from |xᵈyᵈ| ≤ 0.022 to |yᵈ| ≤ 0.17 to |xᵈ| ≤ 0.15–0.17 for Dᵈ, both with masses of Mᴰ = 600 GeV. Other than that, the analysis of the data from single top production shows that the reduction of the pᵀ space can further improve these constraints.

Keyphrases: Beyond standard model physics, Hadronic colliders, Scalar diquarks, Single top production, Dijet production