NCube/papyrus huggingface dataset:
Does practising hypnosis-derived communication techniques by
oncology nurses translate into reduced pain and distress in their patients? : an
exploratory study

Objectives: To explore the effects of a hypnotic communication (HC) training for pediatric nurses in decreasing patients’ pain and distress during venipunctures. Methods: A 4- day theoretical and practical HC training was offered to 5 pediatric oncology nurses. The effects of HC were tested with 22 young cancer patients (13 girls, 9 boys, 10±4 years) over 4 timepoints, with 88 encounters being video-recorded and coded in stable professional-patient dyads. Patients’ pain and distress were rated by patients and parents with visual analogue scales and coded from recordings using the Faces, Legs, Activity, Cry and Consolability (FLACC) scale. Results: We observed a significant decrease in pre-post distress reported by parents (d=0.45, p=0.046). Two (out of 5) nurses with higher skills acquisition had larger reduction in patients’ self-reported pain (d=1.03, p=0.028), parents perceived pain (d=1.09, p=0.042), distress (d=1.05, p=0.043) as well as observed pain (d=1.22 p=0.025). Favorable results on pain and distress did not maintain at follow-up. Conclusion and clinical implications: Training nurses in HC may translate into improved pain and distress in patients, both self-rated and observed provided that skills are used in practice. HC training is a promising non-pharmacological intervention to address pain in pediatrics.

Keyphrases: Procedural pain, Distress, Pediatric, Hematology oncology, Hypnotic communication, Nurses’ training
Do professionals change their communication behaviours following a training in hypnosis-derived communication? : a feasibility study in pediatric oncology

Objectives The purpose of this study was to test the feasibility of a training in hypnotic communication techniques (HCTech) for pediatric nurses to prevent procedural pain and distress in children during venipunctures. Specifically, this study aimed to (1) assess nurses’ mastery of HCTech and (2) nurses’ experience regarding the training program.  Methods Participants were 6 female pediatric nurses and 33 of their cancer patients. Nurses took part in a 4-day theoretical and practical training in HCTech. Venipuncture procedures were video-recorded and assessed to evaluate nurses’ mastery of HCTech using a standardized scale. Pre-training use of HCTech was compared with post-training and follow-up for the entire nurse sample and across nurses with the same patients (109 nurse-patient interactions). After the follow-up, nurses were questioned about their experience in regards to the training and activities (themes and practice).  Results Results showed medium pre-post changes in hypnotic communication behaviours (pre-post d = 0.74), with changes maintaining at follow-up (pre-follow-up d = 0.97). Interviews transcripts’ analyses revealed moderate levels of motivation and satisfaction regarding the training content and format. Nurses suggested to emphasize on the practice of HCTech in a noisy outpatient clinic as well as offer more practical exercises.  Conclusion A 4-day training in hypnotic communication techniques translated into the use of HCTech by nurses practicing in pediatric oncology when comparing the same dyads at baseline, post-training and follow-up. Results support further refinement and suggest nurses could be trained to prevent pain and distress with hypnosis-derived communication strategies.

Keyphrases: Hypnosis-derived communication, Healthcare professionals, Nurses, Pediatrics, Oncology, Venipunctures, Pain, Procedural distress
Un MOOC sur les compétences informationnelles : innovations pédagogiques et processus de design

Les bibliothèques de l'Université de Montréal ont conçu et mis en ligne un MOOC sur les compétences informationnelles nommé « BoniCI - Repérer et gérer l'information ». D'abord élaboré avec Moodle pour être implanté de manière complète ou modulaire dans des cours disciplinaires, nous expliquons comment nous avons adapté son fonctionnement pour le rendre autoportant sur la plateforme Edx. Nous détaillons comment les innovations pédagogiques, basées sur des tests formatifs et un engagement conversationnel, sont appuyées sur les données probantes en enseignement. Nous montrons aussi comment le processus de design a permis l'amélioration de l'expérience utilisateur de l'apprenant. Des premiers résultats d'utilisation sont présentés.

Keyphrases: MOOC, Cours en ligne, Compétences informationnelles, Éducation basée sur les preuves, Processus de design, Effet test, Rétroaction, Théorie de la charge cognitive
Platelets selectively regulate the release of BDNF, but not that of its precursor protein, proBDNF

Background: Brain-derived neurotrophic factor (BDNF) plays a role in synaptic plasticity and neuroprotection. BDNF has well-established pro-survival effects, whereas its precursor protein, proBDNF, induces apoptosis. Thus, it has been suggested that the proBDNF/BDNF ratio could be an indicator of neuronal health. Access to neurons is, understandably, limited. Because of their similarities, platelets have been put forward as a non-invasive biomarker of neuronal health; indeed, they store large quantities of BDNF and can release it into circulation upon activation, similarly to neurons. However, whether platelets also express the precursor proBDNF protein remains unknown. We therefore sought to characterize proBDNF levels in human platelets and plasma.  Methods: The presence of proBDNF was assessed by immunoblotting, cell fractionation, flow cytometry, and confocal microscopy in washed platelets from 10 healthy volunteers. Platelets from 20 independent healthy volunteers were activated with several classical agonists and the release of BDNF and proBDNF into plasma was quantified by ELISA.  Results: Platelets expressed detectable levels of proBDNF (21 ± 13 fmol/250 x 106 platelets). ProBDNF expression was mainly localized in the intracellular compartment. The proBDNF to BDNF molar ratio was ~1:5 in platelets and 10:1 in plasma. In stark contrast to the release of BDNF during platelet activation, intraplatelet and plasma concentrations of proBDNF remained stable following stimulation with classical platelet agonists, consistent with non-granular expression.  Conclusions: Platelets express both the mature and the precursor form of BDNF. Whether the intraplatelet proBDNF to BDNF ratio could be used as a non-invasive biomarker of cognitive health warrants further investigation.

Keyphrases: Platelets, Brain-derived neurotrophic factor, Secretion, Plasma, Pro-BDNF
Contributing factors of unmet needs among young adult survivors of childhood acute lymphoblastic leukemia with comorbidities

Purpose: This study aimed to: (1) describe the domains and levels of unmet needs of young adult survivors of childhood acute lymphoblastic leukemia (cALL) with comorbidities, and (2) to explore the factors associated with higher levels of unmet needs. Unmet need was considered as supportive care needs not met.  Methods: The most vulnerable cALL survivors from the PETALE study cohort completed the Short-Form Survivor Unmet Needs Survey, the Brief Pain Inventory and the 15D instrument of health-related quality of life. Demographic and clinical information, including comorbidities, were obtained from medical records or self-reporting. The participants' needs and contributing factors to their needs were evaluated using nonparametric tests.  Results: Of the 72 participants, 9 (13%) reported moderate/high levels of overall unmet needs. “Worry about earning money” (56%) and “Dealing with feeling tired” (51%) were the most frequent unmet needs (all levels combined). The factors associated significantly with any domain of unmet needs were: having a comorbidity, reporting altered functional health status, high ALL risk status, pain, age (<26 years), and having previously received psychological support.  Conclusion: A minority of young adult survivors of cALL with comorbidities interviewed reported moderate/high levels of unmet needs. However, financial concerns and emotional health and relationship are the two domains of greatest need. Survivors with altered health condition are most at risk of experiencing moderate/high levels of unmet needs. If confirmed in larger samples, interventions should target modifiable contributors of unmet needs such as physical health and comfort, fatigue, and emotional health.

Keyphrases: Childhood acute lymphoblastic leukemia, Late adverse effects, Morbidities, Unmet needs, Supportive care needs, Survivorship
Comparative risk judgments and actual risk-taking in sexual behaviours

HIV infection still represents a major health problem. Risk-taking or the absence of precautionary behaviour is the first determinant for infection. Comparative risk could help explain some part of the risk-taking. However the relation to actual behaviour bears major methodological difficulties which we attempted to address here. Risk status and situation conditionality were considered as independent variables. Comparative risk estimates were considered dependent variables. Two hundred and sixty eight students were included in a correlational design. They filled in self-questionnaires and reported their risk status concerning HIV infection and comparative risk estimates for both conditional and unconditional risk situations. Results confirmed previous research where estimates varied according to risk status and conditionality was related to lower optimistic bias or increase pessimistic bias. When both variables are considered simultanously, risk-takers appraised comparative risk less pessimistically. Different interpretations accounting for this phenomenon are considered. L'infection au VIH représente encore un problème de santé publique majeure. La prise de risque ou l'absence de comportement de protection est le facteur causal déterminant de l'infection. Le risque perçu comparatif pourrait en partie rendre compte de ce facteur. Cependant la relation directe avec le comportement recèle des difficultés méthodologiques importantes, auxquelles nous tentons de nous adresser ici. Nous considérons deux variables indépendantes, le caractère à risque ou non des sujets et le caractère conditionnel ou non des situations proposées pour l'évaluation subjective des risques comparatifs. Cette dernière évaluation est notre variable dépendante observée. 268 étudiants ont été inclus dans cette étude corrélationnelle. Ils ont rempli des questionnaires autoadministrés portant sur les comportements sexuels et des estimations de risques comparatifs. Les résultats confirment les recherches précédentes où l'estimation subjective des risques varie en fonction du caractère à risque des sujets et du caractère conditonnel des situations. Lorsque les deux variables indépendantes sont considérées simultanément, on observe que les preneurs de risque jugent certaines situations conditionelles de manière moins pessimiste que le reste de l'échantillon. Différentes interprétations de ce phénomène sont envisagées.

Keyphrases: Comparative risk, HIV, Optimism, Pessimism, Conditional risk, Risque comparatif, VIH, Optimisme, Pessimisme, Risque conditionnel
Identifying domains of quality of life in children with cancer undergoing palliative care : a qualitative study with professionals

Objective: The goal of pediatric palliative care (PPC) is to maintain the quality of life (QoL) of children whose lives are threatened. However, there are sparse scientific data on the domains of QoL in this particular context, and no measurement strategies are available. The present study aims to describe the domains of QoL in the context of PPC in oncology, according to the perceptions of professional caregivers.  Method: Semistructured interviews were conducted with a random sample of 20 professional caregivers from the Division of Hematology/Oncology at Le Centre Hospitalier Universitaire Sainte-Justine (Montréal, Canada). The caregivers were asked about their perceptions about the QoL of the children they have cared for in this context. The data were analyzed using inductive thematic content analysis.  Results: The analysis allowed us to identify seven domains of QoL: “physical comfort,” “alleviation of psychological suffering,” “fun and the present moment,” “sense of control,” “feeling valued and appreciated,” “feeling that life goes on,” and “meaningful social relationships.”  Significance of Results: Caregivers recount the regard that should be accorded to maintaining well-being and a sense of fun, as well as fostering the child's abilities, taking account of the progression of the disease, and to fulfilling his or her needs, especially social ones. Our results also demonstrate that all domains were positively referred to by professional caregivers. The data from our study will lead to better assessment of QoL according to the trajectory of a child with advanced cancer while undergoing PPC.

Keyphrases: Pediatric palliative care, Quality of life, Cancer, Professionals, Qualitative study
Quality of life, treatment beliefs, and treatment satisfaction in children treated for primary immunodeficiency with SCIg

Despite the development of subcutaneous treatment, children and adolescents with primary immunodeficiency (PID) are vulnerable to a lower quality of life (QoL) than non-clinical participants. Comparisons have been offered in rare reports with limited sample sizes. No description is available of treatment beliefs and treatment satisfaction with standard tools. The objective of this study was to describe a large sample of patients with pediatric PID on QoL, treatment beliefs and satisfaction, and identify perceived benefits and issues of treatment both in children and parents. A mail-back survey was conducted in 60 patients with PID treated with subcutaneous Ig and their parents from a clinic in Montreal (QC, Canada). We used the standardized tools to assess for QoL levels, beliefs of necessity and concerns with treatment, and dimensions of satisfaction. We collected and coded perceived benefits and issues through open-ended questions. We found lower QoL in children with PID than in healthy non-clinical participants (median d = 0.40) and similar QoL levels to children with cancer (median d = 0.12). Participants considered their treatment as less necessary and able to control the illness and less convenient than patients with other conditions. Children were more prone to consider the treatment as convenient (69 vs. 47% p = .028) but reported more discomfort (24 vs. 10% p = .043) than parents. Results suggest a lower-than-expected QoL in pediatric PID. Aspects of the illness and treatment are probably unclear to patients and their families, as necessity beliefs were lower than expected. Educational strategies should be developed and assessed to address this issue.

Keyphrases: Primary immunodeficiency, Quality of life, SCIg, Treatment beliefs, Satisfaction
Diagnosing intramammary infection : a scoping review and meta-analysis on frequency and udder-health relevance of microorganism species retrieved in bovine milk samples

The scoping review methodology protocol. There are two parts described: scoping review procedure and details on meta-analysis.

Keyphrases: Mastitis, Microorganism, Milk, Meta-analysis, Bovine, Diagnosing, MALDI-TOF
The ecosystem of peatland research : a bibliometric analysis

Peatlands provide a range of services to societies, such as sequestration of organic carbon, biodiversity protection, attenuation of water flow, and the provision of fuel, wood and fruit, among others. Despite their global importance, no study has yet characterised peatland research on a global scale. This study aims at providing a better understanding of the geographical distribution of peatland research, of its variations through time, and of the specific topics studied. Results show that peatland research has, between 1991 and 2017, become increasingly international and diversified, with more countries and study sites active, and an increase in foreign sites studied. We do observe, however, that the general vast peatland regions of the world showed relatively distinct profiles in terms of topics which, in most cases, are related to their geographical features. Peatland research has a spatial imbalance in favour of central Europe, with studies in Africa and Brazil highly under-represented in relation to their area, and those in western and eastern Siberia moderately under-represented. We also observe some topics have become increasingly studied during recent decades, e.g. climate change, fire, restoration and carbon, while others have been decreasingly studied, such as botany, nitrogen and coal.

Keyphrases: Bibliometrics, Ecosystem, Internationalisation, Peatland, Topic
Detection of Fusobacterium nucleatum in feces and colorectal mucosa as a risk factor for colorectal cancer : a systematic review and meta-analysis

Background: Colorectal cancer (CRC) is a major cause of cancer deaths worldwide. Accumulating evidence suggests a potentially important role of colorectal infection with Fusobacterium nucleatum (F. nucleatum) in colorectal carcinogenesis. We conducted a systematic review, including both a qualitative synthesis and a metaanalysis, to synthesize the evidence from the epidemiological literature on the association between F. nucleatum detection in the colon/rectum and CRC. Methods: A systematic literature search of Ovid MEDLINE(R), Embase, Web of Science Core Collection, EBM Reviews—Cochrane Database of Systematic Reviews, and CINAHL Plus with Full Text was conducted using earliest inclusive dates up to 4 October 2020. Eligible studies were original, comparative observational studies that reported results on colorectal F. nucleatum detection and CRC. Two independent reviewers extracted the relevant information. Odds ratio (OR) estimates were pooled across studies using the random effects model. NewcastleOttawa scale was used to critically appraise study quality. Results: Twenty-four studies were included in the systematic review, of which 12 were included in the metaanalysis. Studies investigated F. nucleatum in feces, colorectal tissue samples, or both. In most studies included in the systematic review, the load of F. nucleatum was higher, on average, in specimens from CRC patients than in those from CRC-free controls. Meta-analysis showed a positive association between F. nucleatum detection in colorectal specimens and CRC (OR = 8.3; 95% confidence interval (95% CI) 5.2 to 13.0). Conclusions: The results of this systematic review suggest that F. nucleatum in the colon/rectum is associated with CRC.

Keyphrases: Colorectal cancer, Fusobacterium nucleatum, Systematic review, Meta-analysis
Risk perceptions among potential Airbnb hosts

Airbnb has taken advantage of recent technological advances to emerge as a disruptive innovation in the tourism and hotel industry. Attracting millions of customers annually, it is present in over 65,000 cities in 191 countries. Its rapid success has attracted research, most focused on guests and their intention to use or recommend the service. This study assesses perceived risk among Airbnb hosts, focusing on hosts’ perception of risks related to services offered, finances, safety and security, and psychological, political, and privacy issues. Ease of use is considered among factors that determine hosts’ adoption intention. A survey of young adults in Dubai revealed a positive correlation between adoption intention and financial risk and time concern, and a negative correlation between safety and security risk, psychological, political, privacy risks, ease of adoption, and adoption intention. This study informs Airbnb management of concerns that might affect business continuity and recommends strategies to address the issues. Airbnb a profité des récentes avancées technologiques pour devenir une innovation de rupture dans l'industrie du tourisme et de l'hôtellerie. Il attire des millions de clients chaque année. Il est présent dans plus de 65 000 villes de 191 pays. Son succès rapide a attiré la recherche, la plupart du temps sur les clients ciblés et leur intention d'utiliser ou de recommander le service. Cette étude évalue le risque perçu parmi les hôtes Airbnb, en se concentrant sur la perception par les hôtes des risques liés aux services offerts, aux finances, à la sûreté et à la sécurité et aux problèmes psychologiques, politiques et de confidentialité. La facilité d’utilisation fait partie des facteurs qui déterminent l’intention d’adoption des hôtes. Une enquête auprès de jeunes adultes à Dubaï a révélé une corrélation positive entre l'intention d'adoption et le risque financier et le souci du temps, et une corrélation négative entre les risques pour la sûreté et la sécurité, les risques psychologiques, politiques, de confidentialité, la facilité d'adoption et l'intention d'adoption. Cette étude informe la direction d'Airbnb des préoccupations susceptibles d'affecter la continuité des activités et recommande des stratégies pour résoudre ces problèmes.

Keyphrases: Adaptation, Innovation, Research, Sci Tech, Scientific, Technical, Technology, Technique, Philosophy, Ethics, Economics, Innovation, Recherche, Scientifique, Technologie, Philosophie, Éthique, Économie
Le don pur et parfait

The gift, theorized by Marcel Mauss, has been mainly integrated into economics in its malevolent form. This is underlined by the economic theories of the political market, labor or charity market. This conception contrasts with the benevolent of altruism and the alternative aspect attributed to this practice in regard to the market. To better understand the impure gift, if not the malevolence, this article specifies the definition of a pure (donor) and perfect (recipient) gift. This reference situation implies rational and moral conditions. Le don/contre don, théorisé par Mauss, a été principalement intégré en économie sous sa forme malveillante. Ce que soulignent les théories économiques du marché politique, du travail ou de la charité. Cette conception tranche avec le préjugé bienveillant de l’altruisme et le côté alternatif attribué à cette pratique par rapport au marché. Pour mieux comprendre le don impur, sinon la malveillance, cet article précise la définition d'un don pur (donateur) et parfait (receveur). Cette situation de référence implique des conditions rationnelles et morales.

Keyphrases: Gift, Malevolence, Benevolence, Don, Philosophy, Ethics, Economics, Don, Malveillance, Bienveillance, Philosophie, Éthique, Économie