MurphyA/hacker-news huggingface dataset:
by timr | 2025-09-30 21:39:53+00:00
You should actually read the article. In particular:

> Fourteen trials recruited patients with specific conditions (raised lipids, diabetes, hypertension, microalbuminuria). All‐cause mortality was reduced by statins (OR 0.86, 95% CI 0.79 to 0.94); as was combined fatal and non‐fatal CVD RR 0.75 (95% CI 0.70 to 0.81), combined fatal and non‐fatal CHD events RR 0.73 (95% CI 0.67 to 0.80) and combined fatal and non‐fatal stroke (RR 0.78, 95% CI 0.68 to 0.89). Reduction of revascularisation rates (RR 0.62, 95% CI 0.54 to 0.72) was also seen.

So the evidence base is a collection of studies where most of the participants had at least one prior indicator of CVD or diabetes, and their outcome is a relatively weak benefit to all-cause mortality, CVD, CHD and stroke. For primary prevention, what you really want is a strong outcome in a study of people without any prior indication of disease [1].

I think the article posted by parent is exaggerating, but even the Cochrane review is pulling its punches here, saying specifically "cost-effective in primary prevention", instead of the stronger claim. Common jokes about putting statins in the water supply aside, there's not a ton of evidence for giving them to, say, otherwise healthy 20-somethings.

[1] Imagine the following, not-uncommon scenario: you have an otherwise healthy patient who is both pre-diabetic, as well as presenting with elevated cholesterol. Statins have a tendency to elevate blood glucose. So which risk do you choose?

The available evidence provides poor guidance.
by maxglute | 2025-09-30 21:40:13+00:00
COMAC can only compete (geopolical drama aside) if engine efficiency improves or fuel prices decreases. TLDR every bit of COMAC can be modern / tier1 (and most of it is), but at current aviation fuel prices, 10-15% efficiency gap in engines will save more money on fuel over airframe lifetime. C919 is basically a 2025 narrow with a 2015 engine, but that old engine alone makes it not economically viable in most markets AT current aviation fuel prices. COMAC makes a lot of sense for PRC economically, not giving a cent to boeing, can build out COMAC specific support across country easily, but it's still commercially not well priced.

The caveate being COMAC is only expensive / has limited room to discount because it uses a lot of western components (for easy regulation/certification only). If PRC moves to a full soveign civil aviation stack, it would probably be very possible to price COMAC competitively, but that's more a medium/long term project. That's probably how it goes the way things are gonig, US probably not going to even certify/liimt where PRC planes can land to kneecap COMAC. PRC + RU can probably do some shenanigans like prevent US planes from flying over their airspace in retaliation and then it's a matter of how much divertion (extra fuel+travel costs) impact bottom line. At the end of the day geopolitics will determine how viable civil aviation projects are.
by buildsjets | 2025-09-30 21:40:56+00:00
Seat and aisle widths are customer selectable options. Hence, a customer may order a 787 with 3-3-3 seating or 2-4-2 seating. The vast majority of airlines chose sardines instead of comfort. In a 737, customers only can get 3-3 seating, but they can choose wide (17.8”) seats and skinny aisles, like Southwest does, or they can choose skinny (17.1”) seats and wider aisles, like Alaska does.
by yjftsjthsd-h | 2025-09-30 21:41:46+00:00
Since the attack does work cross-VM with KVM, it would then seem that Xen really has two advantages, and it kinda only got out unscathed because of the combination of both:

* management stuff mostly lives in Dom0

* Xen does the flushes to protect VMs from each other

If you didn't do the first, then attacks on the host might work, and if you didn't do the second then attacks on Dom0 might work, but the combination blocks both vectors. Is that about right?
by btilly | 2025-09-30 21:42:03+00:00
You're literally talking about how I should regard the hypothetical answers that might be produced by something that I think doesn't exist. There's a pretty clear case of putting the cart before the horse here.

On being presumptive about what things can exist, that's the whole point of constructivism. Things only exist when you can construct them.

We start with things that everyone accepts, like the natural numbers. We add to that all of the mathematical entities that can be constructed from those things. This provides us with a closed and countable universe of possible mathematical entities. We have a pretty clear notion of what it means for something in this universe to exist. We cannot be convinced of the existence of anything that is outside of the universe without making extra philosophical assumptions. Philosophical assumptions of exactly the kind that constructivists do not like.

This constructible universe includes a model of computation that fits Turing machines. But it does not contain the ability to describe or run any procedure that can't fit onto a Turing machine.

Therefore an oracle to decide the Halting problem does not exist within the constructible universe. And so your ability to imagine such an oracle, won't convince a constructivist to accept its existence.
by Rudybega | 2025-09-30 21:42:39+00:00
I think AI is starting to verge on making actual good music. The latest Suno release is wild.

An example here: https://v.redd.it/fqlqrgumo5rf1

I find this one interesting because Rap has classically been difficult for these models (I think because it's technically difficult to find the right rhythms and flow for a given set of lyrics).
by krick | 2025-09-30 21:42:57+00:00
Genuinely curious: is it even still relevant today? I've got the impression that there were a lot of these elaborate techniques and algorithms before around 2016, some of which I even learned, which subsequently were basically just replaced by some single NN-model trained somewhere in Facebook, which you maybe need to fine-tune to your specific task. So it's all got boring, and learning them today is akin to learning abacus or finding antiderivatives by hand at best.
by alphazard | 2025-09-30 21:43:33+00:00
Yes, and the internet has helped quite a bit with this. Instead of a small group of people having access to research through university or hospital publishing networks, everything circulates on the internet for anyone to look at.

My prediction is that this leads to many secular trends in diet and lifestyle. People have called keto a fad, but to me it looks like what happens when basic human endocrinology and how to manipulate it becomes widely known. I don't expect people to go back to high carb/low fat diets as a weight loss intervention, ever, even once the hype has worn off.
by mrtksn | 2025-09-30 21:44:18+00:00
Electricity bureaucracy, whatever doesn't matter. Huge money is invested into making programmers obsolete and they are claiming that it already happens. If the tech is real, Europeans can just tell it to make them all these apps that American companies may choose to deprive EU to teach them a lesson.

If the AI tech is real then Europeans get their apps no need for American companies anymore. If the tech isn't real then the chat app makers(in Europe that's all Meta, WhatsApp + Messenger. Apple is a no go due to low market share) lose half of their revenue to teach Europeans a lesson. Europeans them switch to Signal, Telegram(Popular all over the place) or Viber(this one popular in Eastern Europe).

If they all decide to boycott, there you have opportunity to hit a 400M market. Let's say Europeans can make AAA games but can't code a chat app, give visa to US developers that were laid off for the last many years to come over. Maybe it's politically unpopular? Maybe they are not the best? That's fine, EU is an open market - anyone who is interested in making billions can just make a chat app and take over the EU market. Indians, Chinese, Turks, Africans, Americans that earn less than billions of dollars. It's a huge opportunity. Instantly.

Meta made $38.4 billion USD revenue in EU last year. It's very unlikely that no one will be interested in taking that. US companies aren't doing charity to EU, it's always their second largest revenue stream after USA.
by Imustaskforhelp | 2025-09-30 21:44:24+00:00
Vercel was already like a landlord leeching off of the closed ecosystem that they had built for next.js

I think that this might be a real nail in the coffin for vercel I suppose but I am at the same time worried about the projects that Vercel seemingly took like nuxt/sveltekit/next which might all have a huge impact if vercel really goes under the bus / bankrupts? (Highly unlikely but you never know the boycotts)

Its just something really unethical to pick sides in a conflict of the side of killing children... I don't really know why he would do something like this which can cause so much backlash / boycott that can really just kill his company.

I am never using vercel again and I genuinely prefer cloudflare or even netlify/railway/sevalia/render etc. could be good and the so many other providers that offer the same thing.

Edit: Another good thing might be to leave serverless altogether and to get servers from hetzner could be something really cool too.

I have found that lightning.ai has a 4gb free cpu that I use sometimes to do some stuff in cloud too sometimes and I don't think that there is a limit to how much you can use and there were definitely some people online that I met that were abusing this a lot by making 10-20 accounts on lightning and I was just sad knowing that it might lead to losing the free thing which I deeply cherish of sometimes.
by 01HNNWZ0MV43FF | 2025-09-30 21:45:26+00:00
> The Cybertruck has no type-approval from the European Union (EU) due to significant passive safety concerns. Several specifications of the Cybertruck, particularly the sharp-edged, stiff stainless-steel body, violate EU safety standards, primarily for the protection of vulnerable road users.

So it's too dangerous for pedestrians. Good, love to see a government stand up for its people now and then
by jajuuka | 2025-09-30 21:45:51+00:00
I think we've settled on the idea that the bipedal human form is most efficient when it's a bit naive. The vacuum robot is more optimal because it's small form allows it to reach all parts of the floor and under small spaces we usually can't get easily. We build tools to do jobs more effectively. Not just to mimic how we've done them before.
by lelanthran | 2025-09-30 21:46:23+00:00
> and there is no downloadable Jira competitor anymore.

How much are you or your enterprise willing to pay for that?

See, the economics just don't make sense. Give me some VC money, a small team of experts in the domain and some runway and I'll give you a self-hosted alternative to Jira.

But the cost for you would be too high and I will go out of business trying to sell software while everyone else is renting it out.
by JumpCrisscross | 2025-09-30 21:47:27+00:00
> You do not cook pasta by cooking time

I learned this the hard way moving to an altitude where water boils around 200°F. Just threw out the timers and started obsessively tasting. Flip side is I make fresh pasta more often because the active work of kneading and shaping is more interesting than standing around eating uncooked pasta.
by worik | 2025-09-30 21:47:39+00:00
>> our dominant paradigms were based on racist and sexist assumptions

> I don't think they actually were.

Open a book!

The dscovery doctrine

In the USA there is westward expansion, both genocidal and racist

Women have only been entitled to equal pay since the 1970s in most places

Indigenous Australians were only considered fully people in the 1960s

Most European countries restricted the rights of Jews until mid nineteenth century (or worse)

The Tasmainian genocide

In New Zealand the invasion of the Waikato

Canadian Christian schools

In New Zealand Māori were denied university education from about 1880 until the 1970s (a very few snuck through, some pretending they were foreign)

It was legal to rape your wife until very recently

When a woman married she had to resign her job (my grandmother)

Until the 1960s in NZ a married woman needed her husband's permission for a bank loan

On and on, from my memory banks. I am no historian nor sociologist so I may have buzzed some details, but you should get the point. The West's dominant paradigms are historically deeply racist and sexist.

More generally it is prejudice and bigotry

Whatever, you should see why DEI, even if it has become a box ticking farce, it has deep roots in desperate need
by _carltg | 2025-09-30 21:48:25+00:00
Yes, this is the main concern I have with this result as well.

In other words, rather than plucking different leaves (augments) from the same branch or tree (source dataset), you should be evaluating it on an entirely different tree.

This paper in essence does not have a validation dataset, it only has a training dataset and evaluates on a subpopulation (even though that population was never trained on)
by lovich | 2025-09-30 21:48:44+00:00
A subset are paid incredibly well. For arbitrary lines im going to put that at 250k+/year in comp by year 2-3 of your career.

Another large cohort is paid pretty well with salaries from 110k-150k by that same point who have effectively no negotiation power and are given “take it or leave it” deals with the only leverage being to find another job

And even for the incredibly well paid ones, as the other commentator noted, there’s documented proof of organized wage suppression by the corporations
by timr | 2025-09-30 21:48:48+00:00
> There is no logical fallacy in play here. Nobody is saying “the argument is wrong because of who said it”.

The OP literally dismissed the parent based on nothing more than the opinions of others.

> When assessing the probable significance of an agglomeration of empirical data, it’s valuable to know what experts in the field think about the data and their consensus about the inferences we can draw from it—even if the consensus might be mistaken

I already conceded that, if you have no ability or capacity to think or investigate the issue yourself, it's perfectly fine to defer to the opinions of others. But in doing so, you remain ignorant on the matter.

> because the consensus is usually right.

No. I understand that's a comforting belief -- and even politically charged, today -- but it's just an assertion.
by byearthithatius | 2025-09-30 21:49:52+00:00
You would still need to study or this would be super slow. When I went to China even after I did DuoLingo for two years I understood only super basic sentences and sometimes I even missed those because of accents. I couldn't learn "new" words or concepts or grammar through immersion, it only gave me the question to ask my wife so I could learn it through study.
by verdverm | 2025-09-30 21:50:03+00:00
A lot of companies are blocking political queries because they want to avoid the PR shenanigans of people baiting the AI into saying something that will offend Dear Leader.

I don't blame them, I blame the media ecosystem the oligarchs are increasingly taking over and using to fuhr'er their hold over the people

Midjourney did this about one year ago
by Imustaskforhelp | 2025-09-30 21:50:07+00:00
Yes I know nothing is performative about this and each day I get a little less hopeful around the VC circle and I genuinely don't understand why he would do something so horrible knowing the backlash but even without knowing, like is taking the side of literal children so hard in this world and why...

I am just out of words frankly for him. I just know that this thing isn't going to fly and would impact vercel as a whole, maybe they might even fear him if they could, I suppose.
by barnabee | 2025-09-30 21:50:45+00:00
I don’t find this at all, even compared to my (now rather old) X-T1.

For quick shots to remember an event or night out, modern phone cameras are fine.

For anything that I’d call photography and actually want to print, display, etc. I rarely if ever get results I’m really happy with from a phone camera.

If you’re in any way interested in photography beyond taking a few snaps at parties and on holidays, I highly recommend getting a real camera. I’ve found the Fuji system to be great, from the lenses to the out of camera JPEGs and film simulations that mean you can pretty much avoid doing any significant editing or post-processing if, like me, you find that all quite tedious.
by dragonwriter | 2025-09-30 21:50:52+00:00
The category of civil liability for which the compliance with the DMCA notice and takedown rules offers a safe harbor, first of all, doesn’t overlap with the conduct which constitutes criminal infringement but, more importantly, even if it did the DMCA safe harbor only applies to civil and not criminal liability in the first place.

“Following the DMCA” is irrelevant to anything the FBI would be involved in.
by halJordan | 2025-09-30 21:51:14+00:00
EA is the perfect candidate for private equity to destroy. There are zombie companies that need to be eviscerated, digested, and then excreted back into the world. The megacompanies of the video game industry are the result of a broken market and this is "nature healing itself." The free market will course correct and private equity is a perfectly acceptable vehicle for something like EA
by cryzinger | 2025-09-30 21:51:28+00:00
Curious about infliximab being unhelpful or even harmful for cardiovascular risk; I'm not sure if there were any confounding factors re. people on infliximab not generally being in great health to begin with. But back when I was on infliximab I had some not-awesome systemic side effects, so I wouldn't be chocked if it's just not great for your cardiovascular health in general. (And that's still probably a worthwhile tradeoff if you're the kind of person who's being prescribed infliximab.)
by bluGill | 2025-09-30 21:51:37+00:00
That depends on how much is needed. I've lived in houses with doors I need to turn sideways to get through (and I'm a wide guy - I expect fat people couldn't fit in any direction. I've lived in houses where all doors are bit enough for a wheelchair. Most houses have a range of sizes - what is your requirements. Some things are "easy" to do, and some are a major tear down. Without knowing the exact size requirements of a real robot we can't have this discussion. Though If you are in the business I expect you to look at houses and try to come up with something reasonable unless there is a good reason you can't.

There are always first adopters who will if it isn't too expensive. Rich people often live in a house with big enough doors (well most doors big enough - enough for this discussion to say they do), and likely have a need (and the money) for something even if it isn't very good. If your robot starts to prove useful people will ask for it - we build thousands of new houses/apartments every year just in the US, if builders see a demand they will make changes to their new models - it doesn't cost that much more so they don't even need a real demand, just a marketing feature that you could even if nobody does will work (for a few years: you better prove it useful to those who buy new houses fast or the fad will pass!)

It isn't easy because as you say, chicken and egg. If these prove useful people will make changes of the next few decades so they can have one. (though of course your competition will be looking to see if they can make something that doesn't need a remodel to use)
by ryandrake | 2025-09-30 21:51:40+00:00
I don't think anyone anywhere on the totem pole: from the junior engineer, to the engineering manager, to the founder, to the VC, to the investors, cares if it's actually AI. They just want to see the word there. Someone got it into their head that "AI is the thing now" and now the junior engineer isn't going to get hired unless he says AI. The Eng manager is not going to get promoted unless he talks about managing AI. The Founder is not going to be funded unless he says the company relates to AI. The VC is not going to line up investors unless he says AI. And investors have no clue what to do with their money, but heard somewhere that "AI is the thing now" and that's where they want to flush their money.

Nobody really wants any of this shit as a product.
by kjs3 | 2025-09-30 21:51:45+00:00
I think it's a little more than that. The Lisp machines were very expensive (though the single chip version made things like a MacIvory or MicroExplorer somewhat more affordable), very proprietary, and generally didn't run the software the mass market was looking for (not that they couldn't...there just was never a Lotus-123 or Wordstar for Symbolics). So there was probably never a path to real economy of scale.

But otherwise I think you're spot on, and it's a common arc in this industry: company comes up with a true innovation solving a problem better than the competitors, Moores law does it's thing, suddenly the COTS products are competitive through brute force if nothing else at a lower price point, and company either has to innovate again or embrace a COTS platform. Jim Gettys wrote a neat paper about how this effected high-end video cards back in the early X11 days (admittedly, no longer directly applicable since GPUs are the COTS solution now, but the principle stands).
by thewebguyd | 2025-09-30 21:52:16+00:00
Yeah. At the end of the day, these will be laptops running Android but with a ChromeOS-like experience on top.

Devs (including Google themselves) already neglect Android tablets as is, hell even Android on the phone is neglected when comparing app quality to iOS. Look at the amount of well designed bespoke little iOS apps vs. what's available on Android, and anything available on both already treats Android as a second class citizen.

Even being able to run a Linux VM, these won't touch iPad market share at all.
by zer00eyz | 2025-09-30 21:52:54+00:00
> There's no inherent terror in it.

Go watch the classic black and white "Frankenstein" for a portrayal of mob justice. Torches and pitchforks!

How about the French Revolution... where the head of the mob meets the same end, with the loss of his head?

> Self governing communities on the internet need some means to monitor themselves just like they do offline.

This is also an accurate description of a lynching. You think we're doing better on line, see reddit getting the Boston bomber wrong.
by worik | 2025-09-30 21:53:05+00:00
Surely there is some implied right, as a user and developer on Nix to take part in the forums?

Should the quality of your opinions, outside the forum, be considered?

It is a difficult problem when dealing with notorious assholes. If they are playing a constructive part inside the organisation, at what level of notoriety and assholeness should the moderators pull the pin?
by kelnos | 2025-09-30 21:53:15+00:00
> But it means when another community member refuses to work with you, or belittles your work constantly, there is nothing to be done.

No it doesn't. It just means that there isn't a formal process. The aggrieved party can always contact the project leaders/maintainers, and lodge a complaint.

Sure, the leaders may not do anything with your complaint, but a CoC doesn't guarantee that they will either (even if it does give you a warm fuzzy feeling up-front that they might).

I find it incredibly infantilizing this idea that people can't be good to each other, or people can't feel safe, without some sort of document that lays out behavior expectations. It's so so simple: don't be a dick to people. If someone is being a dick to you, find someone with authority and send them the evidence. If they handle it to your satisfaction, great. If not, stay away from that project, because it's run by people who at worst don't care about you, or at best are inept at handling this sort of thing (and in either case, a CoC is not going to make it better).

For leaders/maintainers, grow a spine. If someone is behaving badly (regardless of whether or not someone complains), talk to them and give them a chance to improve. If their behavior gets better, great. If not, eject them from the community. If they or others aren't happy with your reaction, that's their problem, not yours.