MurphyA/hacker-news huggingface dataset:
by zukzuk | 2025-08-27 00:40:31+00:00
This is a massive problem in healthcare, at least here in Canada. Most of the common EMRs doctors and other practitioners use either don’t have APIs, or if APIs exist they are closely guarded by the EMR vendors. And EMRs are just one of the many software tools clinics have to juggle.

I’d argue that lack of interoperability is one of the biggest problems in the healthcare system here, and getting access to data through the UI intended for humans might just end up being the only feasible solution.
by fooker | 2025-08-27 00:41:28+00:00
We do use oxidation to generate energy.

Of glucose, not a hydrocarbon, but there are plenty of organisms that use hydrocarbons directly.

We don't because we use glucose as our easily transportable fuel, which we evolved because plants happened to produce glucose when we evolved. If there were plants producing some hydrocarbon in fruits we'd have evolved mitochondria to use that instead.
by isbwkisbakadqv | 2025-08-27 00:41:50+00:00
That’s not accurate in the case of osteopenia. It’s defined by a T score. The quantile of the distribution of bone density measurements of young, healthy people that matched the bone density of this patient. Treatments for osteopenia are basically making sure you’re getting enough calcium, vitaD, and high impact exercise…if everyone did all those things (and they worked), the rate of osteopenia would drop to zero.
by asveikau | 2025-08-27 00:42:13+00:00
"Blind" has way more of a wide definition than we usually appreciate.

I volunteer at a food pantry. There is one old lady who is sometimes rude in the line, shoving through saying "move it, I'm blind!!" She sometimes informs me that produce I hand her has black spots and she doesn't want it.

I believe she may actually be legally blind.
by zulban | 2025-08-27 00:42:27+00:00
I got a MR the other day that should be 40 lines of code but it was 1000. It "mostly" worked. Do I pick apart this slop? Why should I? It's bad for the team and for the project.

It's hard to respond to that. I'm genuinely stumped. As I explain in the post, this is me trying to write something re-usable to share with people who do that to a team lead.
by michaelmrose | 2025-08-27 00:44:18+00:00
Being blind or disabled isn't anything like dying of cancer.

We allow compassionate testing of therapies that might allow you to live longer because the alternative is an ugly death.

Consent is never ever ever implied and you don't have to deliberately do a poor job to be liable.

Just not having good evidence of the therapy is liable to improve their lot and doing it anyway or failing to impart an accurate picture of the risks because you don't know enough to do so.

How can you possibly have informed consent without the same info that you hope to glean?
by chasil | 2025-08-27 00:44:34+00:00
We aren't the target of most viruses.

It could be chaotic, I think.

https://m.youtube.com/watch?v=SbvAaDN1bpE

Are we also eliminating transposons? We would not survive that.

https://en.m.wikipedia.org/wiki/Transposable_element
by dotnet00 | 2025-08-27 00:45:17+00:00
The walls are 3mm thick steel, they're very likely to buckle and tear when it tips over, the residual methane vapor gets out and there are plenty of sources of heat to ignite it.

They don't claim to have any plans of recovering the wreckage, but they have previously fished up wreckage for study, so it's still possible they decide to do that.
by pclmulqdq | 2025-08-27 00:45:29+00:00
What Scott is missing is that the only reason "it did not get to orbit" is of interest at all is that SpaceX keeps claiming they got to orbit with starship. I believe that the trajectories have all been suborbital by design, but it still pisses me off that they keep claiming they got to orbit.

The reason this matters is that if they get into an orbit in a short test, they need to exit that orbit with some sort of active system. So the statement "we got to orbit" implies a lot more technology development than the current flights actually show. I agree with Scott that Starship can easily enter LEO, but I am not so sure it can exit gracefully.
by djmips | 2025-08-27 00:45:36+00:00
"Spacewar!, developed a decade later on the PDP-1 computer model, was funded by the Pentagon and later used in military training."

Yeah, so poorly researched - Spacewar! was not funded by the Pentagon. <eyeroll> And as for military use - maybe they (or an AI) are confusing this with Battlezone...

At least read the wiki page.
by ksec | 2025-08-27 00:45:53+00:00
>It's such a stunning dereliction the US let things get to this point. We were doing the "pivot to Asia" over a decade ago but no one thought to find TSMC on a map and ask whether Intel was driving itself into the dirt? "For want of a nail the kingdom was lost" but in this case the nail is like your entire metallurgical industry outsourced to the territory you plan on fighting over.

There were a few of us warning about this well before it all happened in 2013 and 2014. Predicted the death of Intel, and surge of AMD and TSMC before majority of people even heard of TSMC.

I also feel a little sad about TSMC, now that they have invested a lot in US but US is actively and strategically trying to pop up Intel to compete. But TSMC is at least 2 cycle ahead, meaning 5 - 6 years time. Unless TSMC make any mistakes even in the best case scenario I dont see Intel catching up within that time frame. Especially now they have little to no cash cow. Server, GPU, Consumer CPU are all under threats.
by zoeysmithe | 2025-08-27 00:46:05+00:00
Under a scientific economy like socialism you dont need to be "apex male who exploits the workers under him to get yachts and tax breaks." The workers co-operate and thus the "apex predator" capital owner becomes dismissed the same way our towns and villages in the developed West don't pay fees to warring bands of gangs but instead we've unlocked the Republic and the system of representation and taxes and such via democratic action.

You absolutely can have utopian beings. In fact, I'd argue the greed-based societies get caught in the great filter and if there is a space faring race, its absurdly ethical and fair and, to me, explains the Fermi paradox. They're out there and maybe they see Earth but it would be hugely unethical to intervene here. The proper thing to do would be to only observe us from afar.

If this was a movie or novel maybe the Wow signal was them messing up, or a defector amongst their midst who disagrees with full isolation policies. But most likely it'll end up being something simple. The last good theory I heard was it domestic and was reflected off orbiting space junk, but who knows.
by Geee | 2025-08-27 00:46:07+00:00
Be careful when training AI models on unknown signals, or uploading them publicly on the Internet to be picked up into training datasets. It might be an adversarial data poisoning attack, which is designed to bias the model into servicing the attacker.

In this case, a superintelligent digital lifeform might be literally sending itself across space into every direction, and who knows what it does once it lands into a training dataset somewhere and starts deploying itself.
by shagie | 2025-08-27 00:46:17+00:00
The recent article on the WOW signal is "Arecibo Wow! II: Revised Properties of the Wow! Signal from Archival Ohio SETI Data" https://arxiv.org/abs/2508.10657 by Abel Méndez, Kevin N. Ortiz Ceballos, Jorge I. Zuluaga (and many others)

This is a follow up to a September 2024 paper (the article you link is November 2024)... "Arecibo Wow! I: An Astrophysical Explanation for the Wow! Signal" by Abel Méndez, Kevin Ortiz Ceballos, Jorge I. Zuluaga (just those three).
by schoen | 2025-08-27 00:47:08+00:00
This sequence of events (even though expected!) reminds me a lot of the Monty Python and the Holy Grail speech:

> Listen, lad. I built this kingdom up from nothing. When I started here, all there was was swamp. Other kings said I was daft to build a castle on a swamp, but I built it all the same, just to show 'em. It sank into the swamp. So, I built a second one. That sank into the swamp. So, I built a third one. That burned down, fell over, then sank into the swamp, but the fourth one... stayed up! And that's what you're gonna get, lad: the strongest castle in these islands.

(although I suppose this ship fell over, then burned down, and then sank into the ocean)
by thrance | 2025-08-27 00:47:18+00:00
You have a really bleak and limited view of the far future. Species that have the means to cross interstellar space probably have found ways to alter themselves and removed their need to grow exponentially as they realized it is unsustainable, and are now perfectly content to chill on their homeplanet.

You're thinking of cancer cells with spaceships, not highly advanced beings who have mastered matter and physical reality. I recommend reading Dispora by Greg Egan, it could potentially expand your mind on what the future may actually look like.
by m4rtink | 2025-08-27 00:47:24+00:00
Maybe just some part of the construction (possibly even just the strinngers or simply some nook or cranny that is fully eclosed) got presurized or was pressurized for the whole time by just air that could not escape.

That would be fine for the fligt so far - until it started to heat up from re-entry heating. The stainless steel would be still fine if heated to hundreads of degrees, but the expanding gass could maybe make the enclosed volume to rupture ?

Or a mix of methane and oxygen accumulating somwhere and exploding - but that seems less likely to me in a near vacuum environment during re-entry.
by delta_p_delta_x | 2025-08-27 00:48:29+00:00
I am confused. My point was that if engineers target Windows at all, they ought to do it properly, but you retorted with 'I don't target Windows'. Okay, well and good, then my advice isn't for you and developers like you.

Then again, you said 'don't expect all engineers to write their software specifically to cater for it', seemingly ignoring my and essentially every parent commenter's plea for developers targeting non-Linux platforms to be good citizens on that platform, and adopt platform conventions. If you're not writing software for Windows, then sure, no need to think about Windows. If you are, or you are going to, then this platform convention business needs to happen and needs to be done correctly, whatever your thoughts on Windows, or, in the thread's case, macOS, where application data should go in `~/Library/Application\ Support` and not dot-dirs in $HOME.

The conversation digressed into cherry-picking my explanation of 'hidden file'. I'm not sure the troll epithet is fair.
by SpicyLemonZest | 2025-08-27 00:48:42+00:00
I do not need to and democracy does not require me to. The price of their mistakes is permanent shunning. I'm not going to go around conducting inquisitions, but I find I've been inspired by the tenacity of old folks carrying grudges against communism from the Cold War, and I'm confident I can carry this grudge until I'm an old folk myself.
by bjornsing | 2025-08-27 00:49:24+00:00
Thanks for the extensive answer.

> I don't think the idea of a zero null hypothesis is necessarily mathematically unsound. In cases like the difference in means, a zero null hypothesis is well-posed. However, I agree with you that there are better practices, like a null hypothesis incorporating a nonzero effect.

I don’t think a zero null hypothesis is mathematically unsound of course. But I think it is unsound to do one and then look at the effect size as a known quantity. It’s not a known quantity, it’s a point estimate with a lot of uncertainty. The real underlying correlation may well be a lot lower than the point estimate.

And of course it’s hard to get people in charge interested in better hypothesis testing. That testing will result in fewer conclusions being drawn / fewer papers being published. It’s just another symptom of the core issue: it’s quite convenient to be able to buy the conclusions you want with money.
by fny | 2025-08-27 00:50:06+00:00
Here's a related thought experiment for those hoping for interstellar kumbaya:

On planet Jung dwell the Jungians, sapien-like beings who need only a single cup of a rare liquid to live an entire lifetime. For humans, that same cup grants twenty extra years of healthy life.

Human just landed on the planet Jung and discovered the liquid--what happens next?
by mindcrime | 2025-08-27 00:50:33+00:00
1. Do I believe other life has existed, does exist, and/or will exist elsewhere in the universe? Yes, with pretty close to 100% confidence.

2. Do I believe other intelligent life forms visit earth in their flying saucers, abduct people, anal probe them, abduct and slaughter cows, build pyramids, and - apparently - crash often? No, not really. I mean, I can't rule it out, but my personal subjective Bayesian prior towards this notion would probably be something like 0.001 or so. But that's actually up from years past, as we learn more about more possibly inhabitable planets that are closer to Earth than was previously known, etc.
by echelon | 2025-08-27 00:51:13+00:00
> FluxKontext

Flux Kontext is an editing model, but the set of things it can do is incredibly limited. The style of prompting is very bare bones. Qwen (Alibaba) and SeedEdit (ByteDance) are a little better, but they themselves are nowhere near as smart as Gemini 2.5 Flash or gpt-image-1.

Gemini 2.5 Flash and gpt-image-1 are in a class of their own. Very powerful instructive image editing with the ability to understand multiple reference images.

> Edit: Honestly it might not be the 'gpt4 moment." It's better at combining multiple images, but now I don't think it's better at understanding elaborated text prompt than ChatGPT.

Both gpt-image-1 and Gemini 2.5 Flash feel like "Comfy UI in a prompt", but they're still nascent capabilities that get a lot wrong.

When we get a gpt-image-1 with Midjourney aesthetics, better adherence and latency, then we'll have our "GPT 4" moment. It's coming, but we're not there yet.

They need to learn more image editing tricks.
by 0xDEAFBEAD | 2025-08-27 00:52:04+00:00
My understanding is that there's often at tradeoff between fitness and antiviral resistance. The virus starts on a fitness local maximum, and it has to pay a fitness cost as it evolves resistance to the antiviral (due to stepping off the local maximum). If the antiviral is ineffective, and the virus continues reproducing, over time it will evolve "compensatory mutations" which allow it to regain some or all of the lost fitness.

Based on my recollections of this paper https://pmc.ncbi.nlm.nih.gov/articles/PMC5499642/

So yeah, I wouldn't be super worried about the virus evolving to become worse in absolute terms as a result of antiviral exposure. Virii are evolving all the time anyways. Antivirals can also reduce evolution speed by fighting an infection: A more severe infection means more virions means greater evolution speed. I believe some new COVID variants were thought to have evolved in the body of someone who was severely infected. (However: Note that it's not necessarily beneficial for fitness for the virus to evolve greater infection severity, especially if that interferes with transmission.)
by zahlman | 2025-08-27 00:52:33+00:00
The brown M&Ms themselves could not have caused a serious problem, but were a sign of attention not being paid in an environment where serious problems could occur.

The same is true of the scientific papers mentioning "Gr". Everyone knows what the formula should be (it doesn't directly invalidate the paper), but seeing that implies a lack of attention (and that lack of attention is reason to cast skepticism upon the paper).
by sandreas | 2025-08-27 00:52:44+00:00
You could either try to repair it (it has probably only worn out switches that can be replaced by soldering new ones) or you could build one yourself (search for "github split keyboard choc v2"). There are many projects like Corne, lily58 and others.

Beware: Deep rabbit hole with hardly any escape... I built myself a non-ergo modded Logitech G515 with mill maxed Lofree Kailh Ghost switches (I eventually change this to Hades in the future), which was a ton of work, but I'm so happy everytime I use it.

If I had to buy one I would also have gone non-ergo with Wobkey Crush 80 or EvoWorks Evo 80.

The corne v4 is pretty popular and having Jlc3dp as a 3D print service all you need is time and patience. I recommend to also look for QMK / VIA Firmware as well as ZMK. They have lists of supported hardware.
by SlowTao | 2025-08-27 00:53:30+00:00
That doesn't sound unreasonable. That is Ivy Bridge/Intel Core 3rd gen capabilities. You aren't running a generative AI but can do all manner of work loads. Combined with some software efficiency gains and you could be fairly comfortable.

This part of why I have been advocating for years that the open source/free software folks should be focusing on optimization and stability/security as long term it will probably be much more useful that adding features that can be dumped on top.
by helpfulfrond | 2025-08-27 00:54:21+00:00
They did say short time and non chronic. Is sleep deprivation really something one can experience in a short time? In my definition, doing something very difficult like lifting a heavy weight qualifies as extreme stress and would be beneficial; some other things would not. Maybe it would work better for you if they added the word "moderate" to their definition, but generally I would agree with their assessment.
by wjsekfghks | 2025-08-27 00:54:39+00:00
Completely agreed. The first version of our app was on mobile. We implemented preview deployment for frontend testing (and we were going to work on backend integration testing next). But yeah, without a reliable way to test and verify changes, I agree it's not a complete solution. We are going to work on that next.

FYI, our initial app demo: https://youtu.be/WzFP3799K2Y?feature=shared
by otimizador | 2025-08-27 00:54:56+00:00
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by fluoridation | 2025-08-27 00:56:13+00:00
> If any 32 bit app is launched the shared libraries will be loaded.

Like I said, if the 32-bit stuff is getting used, that's an argument not remove the support.

> And being able to get away with less RAM also improves battery life because keeping RAM refreshed uses energy - again a bigger factor on mobile.

Memory allocation exists purely at the software level. The hardware doesn't understand whether a particular region has been allocated or not; the only difference between an allocated page and an unallocated one is that the former appears in the OS's VMM data structure as allocated (i.e. it's just more bits in memory). The power consumption of RAM scales with the total cells installed, not with how much the OS has decided is "in use".
by monster_truck | 2025-08-27 00:56:28+00:00
I have family like this. They can see enough 'shape' to play something like Tetris extremely well but anything that relies on colors is usually a no. When we were young they had color but that went away first. My understanding is that as they get older the resolution of the shapes gets lower and lower, so they have to make things bigger and be as close as possible.

It was beyond the point of glasses being able to do anything useful for them just as they finished college.
by kace91 | 2025-08-27 00:56:41+00:00
Language is one of the silliest things in modern tech.

I speak fluent English, but my native language is Spanish. I should be the most basic case of bilingualism for an app to handle - my native language is popular, English is the poster child of second language you learn for global communication, the combination itself is common as well...

The amount of stupid assumptions apps and sites make about me is mindboggling.

"Your app and OS is set to English, you watch mostly English content, you use no subtitles and your subscriptions are mostly US-based. let's give you an extremely fake dub over the content you usually watch."

Reddit also auto translate the links I enter and makes them gibberish if I'm not logged in, chagpt switches languages halfway through a message regardless of what I use...It's becoming borderline hostile.
by colinwilyb | 2025-08-27 00:56:44+00:00
I am here because it feels like the last place to enjoy insightful discussion among a diverse group of strangers.

I really enjoy when someone fresh out of college asks a question and a retiree engineer/technician/manager joins the discussion with personal knowledge. The insight and experience here, pending the AI slop takeover, is what you usually find only on very topic-specific forums.

The text-only formatting, culture of contributing to the conversation, and simplicity (read: not shiny and new), hopefully continue to keep out the cesspool of other internet at bay as long as possible.
by Mistletoe | 2025-08-27 00:56:47+00:00
They should plan more long term. In an economic downturn like after 2000, all these nonsense valuations for vaporware are going to go to the center of the earth. And all signs point to another downturn for the next decade.

https://www.currentmarketvaluation.com/models/s&p500-mean-re...
by thrance | 2025-08-27 00:57:30+00:00
If your point is to prove that the patterns of domination and conquests that exist here will necessarily exist in the stars too, then I'm afraid your thought experiment is deeply flawed.

If ever we are able to journey through the interstellar medium, we ought to have achieved immortality by then. We'll probably live as deincarnated beings in virtual worlds, free from any desire to grow exponentially, having realized this is deeply unsustainable and pointless once you have mastery over physical reality.

Read Diaspora by Greg Egan, perhaps it can cure you from this simplistic vision of the far future we have inherited from the 50s pop SciFi books.
by dotnet00 | 2025-08-27 00:57:47+00:00
The intention is to need minimal to no replacement between flights. Part of the purpose of these tests is to figure out how to do that.

The tiles themselves work fine, but how to best mount them? where do you need them? Can you make them thinner? do you need anything underneath? what kind of gap do you need between tiles? Those are the things they're hoping to understand in these tests.

The Shuttle tiles were technically reusable AFAIK. The issue was that they were very fragile and the Shuttle for the most part could not tolerate any heat getting through the tiles (being aluminum), so every flight needed to have a perfect heat shield. Starship is a bit better on that end, as stainless steel is a lot more capable of tolerating heat and I think the tiles are a bit less fragile. Still, would be ideal to figure out how to not drop any tiles.
by happyopossum | 2025-08-27 00:58:37+00:00
> Merge Request (MR): when a programmer submits proposed changes to a project in a structured way. This makes it easy for anyone to see the differences and review the changes. Sometimes called a Pull Request.

Ok, maybe I’m in a bubble, and my job is only coding-adjacent, but I’ve literally never heard a PR called an MR until today. Is this a new thing?