MurphyA/hacker-news huggingface dataset:
by carlsborg | 2025-08-26 18:11:00+00:00
Both are broad spectrum antivirals, but completely different mechanism.

DRACO "is a chimeric protein with one domain that binds to viral double stranded RNA (dsRNA) and a second domain that induces apoptosis when two or more DRACOs crosslink on the same dsRNA." (Ridder et al 2011). This article is about packaging mRNA for a set of 10 interferon-stimulated genes that express multiple proteins that target various stages of viral replication.
by com2kid | 2025-08-26 18:11:01+00:00
One of the first upgrades I made to my house was buying a nice (interior) vent hood. The exterior ones need to be at least a few feet away from the stove, and my stove is right up against the wall it vents out of. I still was able to find an interior one that has 1/2 the noise and twice the airflow of the standard builder grade vent hood.

One annoyance is that almost none of the vent hood stick out far enough, ideally you want the vent hood to stick out a few inches (at least) past the front of the cook top, but almost none of them do that (likely due to head bumping issues, understandable) so a lot of effluent still escapes.
by darth_avocado | 2025-08-26 18:11:03+00:00
> U.S. customs is demanding a Certificate of Analysis (which could cost thousands of dollars and to determine what exact amount of Aluminum, Copper and Steel are in the product), otherwise they assume the entire PCB consists of copper, aluminum, and steel, and charge a 100% tariff on the whole product.

It’s on the whole product not just micrograms of aluminum, which could break the bank based on how much you order.
by MrRadar | 2025-08-26 18:11:19+00:00
Seriously. Also less and less software is supporting 7. Importantly, Firefox ESR 115 is the last modern browser to support Windows 7 and it's entering EOL after this month[1]; Chrome dropped Windows 7 support in 2023[2].

[1] https://support.mozilla.org/en-US/kb/firefox-users-windows-7... [2] https://support.google.com/chrome/a/answer/7100626
Show HN: I Built an Extension to Copy, Paste & Autofill Web Forms Instantly
by indiedev_snow | 2025-08-26 18:11:53+00:00
Hi all! Hope you're all doing well!

I built MultiField CopyCat, a Chrome extension that helps you bulk copy, paste, and autofill multiple web form fields all at once. If you often find yourself retyping or copying form data field by field, this tool might save you time and frustration.

Website: https://multifield-copycat.com/

Quick Youtube demo: https://youtu.be/gi-lKZbawSk

Key features:

- Copy multiple form fields in selected area in one go

- Paste copied data back into the same forms in one go

- Copy & paste all form data from one page to another

- Save autofill settings for recurring use

- Supports common input types like text, checkboxes, radio buttons

- Customizable keyboard shortcuts for quick workflow

I've built this because, as a web developer, I often found myself copying form data between environments, e.g. from local to staging, or staging to live sites. I also test forms during development, so I added the instant autofill feature as well to make it a complete tool for forms. You can also enable/disable the autofill easily via the extension popup as needed.

This is my first time building an extension, so I'm sure there're plenty of room for improvement — feedbacks and suggestions are all very welcome!

You can check it out on the Chrome Web Store here: https://chromewebstore.google.com/detail/alglchohmdikgdjhafi...

Thank you so much for your time & for checking this out! Hope this helps you too!

And thank you WXT team for the amazing extension framework!

---

P.S. It probably sounds stupid: I did use my extension's autofill to save my draft post under https://news.ycombinator.com/submit, but hey it works lol
by gundmc | 2025-08-26 18:11:54+00:00
> Though fair warning, gpt-image-1 is borderline useless as an "editor" since it almost always changes the whole image instead of doing localized inpainting-style edits like Kontext, Qwen, or Nano-Banana.

Came into this thread looking for this post. It's a great way to compare prompt adherence across models. Have you considered adding editing capabilities in a similar way given the recent trend of inpainting-style prompting?
by sdesol | 2025-08-26 18:12:19+00:00
> Therefore, it doesn’t affect my work at all.

But that isn't what the author is talking about. The issues is, your good code can be equal to slop that works. What the author says needs to happen is, you need to find a better way to stand out. I suspect for many businesses where software superiority is not a core requirement, slop that works will be treated the same as non-slop code.
by bullen | 2025-08-26 18:12:28+00:00
X86 uses more electricity than ARM/Risc-V.

So I do not want people to only move to linux (on their X86) but also move to ARM/Risc-V.

Directly from Windows on X86 to Linux on ARM/Risc-V in one go.

Two flies with one hit.

That said all X86 should become linux servers = this is only valid for the client.
by vunderba | 2025-08-26 18:13:14+00:00
I think most of the SOTA models could probably handle this but you'd probably get better results using a pipeline:

1. Reduce article to a synopsis using an LLM

2. Generate 4-5 varying description prompts from the synopsis

3. Feed the prompts to an imagegen model

Though I'd wager that gpt-image-1 (in the ChatGPT) being multimodal could probably managed it as well.
Show HN: I built a tool to create fast, beautiful QR code menus for restaurants
by bilalasd | 2025-08-26 18:13:43+00:00
Hi HN,

I built Morel after getting frustrated with how many restaurants replaced their paper menus with horribly slow, pinch-and-zoom PDFs after the pandemic. The user experience is just awful, especially if you have a bad connection inside a building.

I wanted to build something better: a menu that felt mobile optimized, was incredibly fast, and just worked.

Morel is a simple platform that lets restaurant owners build and host a lightweight and fast menu. The menu viewer itself is highly optimized for mobile phones and has minimal dependencies to ensure it loads instantly, even on a spotty 3G connection or weak restaurant Wi-Fi. The goal was to make it as close to "instant" as possible.

Morel also lets you create and style QR codes that you can print.

The tech stack is: * Frontend/Backend: Next.js / React * Database: PostgreSQL with Prisma * Payments: Stripe * Auth: Clerk

I've just launched and would love to get your feedback on the product, the tech, or any other aspect. I'll be here to answer any questions.

The site is at: https://www.getmorel.com

Thanks,
by semiquaver | 2025-08-26 18:14:03+00:00
No, that is the de minimis exemption repeal. This is due to a series of new tariffs on copper and other metals which is unusual (and nonsensical) in that it applies to the metal content of finished and semi-finished products. The de minimus rule exempted low value individual products sent directly to consumers, but this metal tariff affects all importers, unless they deal in one of the carved-out product categories.
by mwigdahl | 2025-08-26 18:14:19+00:00
My daughter has DBS for severe Tourette's. Her quality of life before the implant was horrible -- frequent 110 dB+ screams and self-injury. The implant has reduced her tic frequency and intensity by easily 95%. It's not only given her her life back but also the lives of her family members.

The potential of brain interface technology is truly incredible -- both for good and ill.
by onetimeusename | 2025-08-26 18:14:51+00:00
I think it's simpler than that. I think US intelligence is looking to make sure a secure supply chain exists for AI and really that just means NVDA's chips. I have never stated at any point this plan would work well. This is all stated in the reasoning for the CHIPS Act. That may mean pressuring people to use the foundry but I don't actually think the concern was chiefly to win back jobs. The funding from the CHIPS Act was actually withheld since Intel wasn't making satisfactory progress. Also the warrants I mentioned are executable only if Intel drops it's stake in the foundry. I believe this was added since there was talk of Intel spinning that out. So the government seems very interested in the viability of the foundry and less so in jobs.

So my point is that I think US Defense is motivated by national security interests but that doesn't mean this plan is going to work well or that we haven't already lost the AI war. It's probably too little too late. I am just pointing out over and over that I don't think grandstanding is the motive. I am sure that will happen but I think at some point it hit US Defense that relying on Taiwan put's us in a precarious situation.
by somenameforme | 2025-08-26 18:15:07+00:00
Yip, I'm a advocate for capitalism but there's definitely a bug with interest/investments in that earning money makes it even easier to earn money, even if you do absolutely nothing with your life. Just dump everything in a diversified portfolio and you become an infinite money printer when you reach the point of having enough money that all your expanses are small relative to your capital gains.

This issue radically distorts the concept of who is contributing to society and who is living off the contributions of others.
by JdeBP | 2025-08-26 18:15:24+00:00
We're going to get loads of these on Hacker News if we're going to get it twice per country's postal system and also individually for each supplier affected in specific ways. (-:

* https://news.ycombinator.com/item?id=45020661

* https://news.ycombinator.com/item?id=44970269

There's an announcement today on the PiHut WWW site, for example.

* https://thepihut.com/pages/delivery

Just a random Bing search turns up loads of these from the past week.

* https://crooked-dice.co.uk/blogs/news/temporary-suspension-o...

* https://www.elgrecominiatures.co.uk/pages/temp-suspension-us...

* https://coscraft.co.uk/blogs/three-nerds-in-a-shed/tariffs-o...

and so on. I suspect that dang and tomhow might have to apply the "It's in the mainstream news and we have umpteen dupes." rule soon. (-:
by blackguardx | 2025-08-26 18:15:35+00:00
The Digi-key situation is funny. Going forward, ordering from Digi-key will be cheaper for europeans than for folks in the US. Digi-key operates a bonded warehouse where they don't pay tariffs until it gets shipped to a customer. ICs that are sent from China to Digi-key and then to europeans will pay no US tariffs and often with free shipping deals as you mentioned.

Digi-key never offerred free shipping for US customers and now we will have to pay these high tariffs too.
by etempleton | 2025-08-26 18:15:44+00:00
There is a lot of doom and gloom regarding Intel, but there are also signs of life. Intel is starting to show off products made on 18a and is slated to ship at least one product on that process this calendar year. Meanwhile TSMC has been stuck on 3nm for quite some time and it appears that there will not be a product with TSMC 2nm this year. If both of these prove true, Intel will have roughly caught up in terms of process. There is a lot more work to be done, but do not underestimate how quickly Intel's fortune can change if they manage to start hitting their mark and TSMC falters even slightly.
by apercu | 2025-08-26 18:16:00+00:00
Funny, you sound a lot like me. And for the record, in addition to my tech "day" job, I work in a live music venue, and a lot of the work is physical labour so I am exposed to both of the paradigms every day. I also own a tractor and split firewood manually. And I'm hoping to get forklift certified soon, because why, not? I, too, have been working since I was very young (15, in Texas, doing roofing, commercial electric and demo) and working people are my people.

Anyway, in some ways I agree more than disagree with you, but I wanted you to understand that I've had all the jobs (restaurant/Bar, field service, tech, executive, manager, director) in a lot of industries because I see value in labour and community. If the other things (welding, fork lifts, live event tech) paid better I would rather do that than work in "tech" to be honest. Real value is measured more effectively in the "real" world. Our industry is far more built on hype and performative gestures and bullshit, frankly.
by bdcravens | 2025-08-26 18:16:18+00:00
Kinda meta, but I found it fascinating seeing the ads that were presumably bought up well in advance, with the same company on the same page in the first few pages of the issue, at least early on. Seeing how it changed over time, I can't help but wonder if that in itself is a bit of a historical record about the growth and death of parts of the industry.
by surprisetalk | 2025-08-26 18:16:36+00:00
git log is probably good enough for 90% of folks :)

The main reason I wanted to build this is that git log doesn't give me context from GitHub PRs/issues/milestones or CI events. When I'm diving into a new codebase, I like to see who's been working on what, and what ongoing problems/initiatives are propelling that development.

I've only got GH issues up (not milestones or CI events yet), but I think this is a good start!
by bjackman | 2025-08-26 18:16:49+00:00
It's nothing like either of those things because both of those things have harms to other people and those harms scale linearly with the amount of consumption. Wasting steak isn't problematic because you run out of cows it's problematic because of the climate impact of raising them.

Saying that saving water is "about respect" or something is idiotic. Saving water is about ensuring there's enough water to go around. This is something you need to do in places where water is scarce and not where it isn't. And if you waste time and energy on saving water you are ultimately making the world poorer.

Obviously I'm simplifying things by talking in absolutes here, but what I said above about "the margin at which it makes sense" gets at the truth of the matter. Installing water-saving taps in Zürich is almost certainly a net harm to the environment.
by zdragnar | 2025-08-26 18:16:59+00:00
The objective and subjective observations are about different but related things.

The objective measurements are about his enhanced abilities. He can do things he couldn't before.

But, the GP comment referred to "quality of life" which is innately difficult to measure objectively. It's possible that he was able to do those things but it caused him enough irritation to do them that he avoided using it (like CPAP often is for example), or that the things it enabled him to do weren't sufficient to warrant feeling improved. My father has limited mobility, but no interest in playing mario kart or adjusting an air filter, and there's very little in his home that he has or would want to be automated. Anything that could be my mom or another family member usually takes care of anyway, even if it's still something he could do himself as he's rather tech illiterate.

So, in this scenario, given my father's age, the risks involved in such a major surgery for his age, and his personal inclinations, the very same additional capabilities likely wouldn't be worthwhile in his opinion. Hence, the subjective experience of the objective changes are how you measure quality of life for this kind of operation.
by uz3snolc3t6fnrq | 2025-08-26 18:17:25+00:00
i've got possible good news for you then, there's a project that adds a translation layer between the two server protocols[0]. it has some limitations dealing with the different quirks and features that differ between both games[1], but it looks like everything else works fine. you could try that out if you find it to be a better option than wrangling with windows updates

as for VR, there's a third party mod for java[2], i tried it a couple years back and it felt pretty smooth, had no issues with it, but i don't have a point of reference to compare it to bedrock VR because i never tried it

[0] https://github.com/GeyserMC/Geyser

[1] https://geysermc.org/wiki/geyser/current-limitations/

[2] https://www.vivecraft.org/
by GeekyBear | 2025-08-26 18:17:36+00:00
> Funny how no one really complained about the random reboots

People definitely complained about the random reboots, especially on the Nexus 6P, since that phone wouldn't boot again until after it was connected a charger plugged into a power outlet.

Heaven forbid you had a medical emergency away from a power outlet with a phone that unreliable.
by FuriouslyAdrift | 2025-08-26 18:18:31+00:00
Yeah I have one specific enterprise app (the updater service for another piece of software) that will not work unless TLS 1.1 is turned on at the OS level. It doesn't do anything with it, but some hard coded phone-home function in the software must fire up each time it checks for updates (even though it doesn't use TLS for the connection, but unencrypted FTP) or it will hard fail and not even log the failure.
by Aurornis | 2025-08-26 18:18:43+00:00
The gap between hardware and software salaries has been strangely stubborn.

I started in hardware and pivoted to software for the same reason: It's easier to find higher paying jobs.

It's been strange to see the gap persist at companies that cling to salary data for compensation decisions. Incredible to see companies complain about not being able to find good hardware talent but then also refuse to pay hardware hires at the same level as software hires.
by madmod | 2025-08-26 18:18:45+00:00
Awesome job on following through with the upgradability! I love the nvidia support!

Are you coming out with another coolermaster case for the 16 mainboard?

I want to make a custom dock with fans to force more cooling over the radiators. Could it be possible to "unlock" the 100W TDP of the 5070 in firmware or are there other hardware limitations like the interconnect?

Was adding the USB C power input on the GPU necessary to get full power? I see in the specs on github that VADP_GPU can take 100W into the mainboard and VSYS_GPU can supply 240W to the GPU. Are there any tradeoffs powering the system from the back ports vs the GPU?

Was the previous version of the AMD GPU not sending the display signal directly to the panel via the edp mux but instead via the igpu? If not is that something you can update in firmware? Can you publish how this was done so someone can make an oculink expansion board with displayport input?

Thanks to everyone at Framework for making such awesome hackable products!
by hajile | 2025-08-26 18:19:06+00:00
Apple never used a uop cache in their designs. ARM dropped uop caches when they removed 32-bit support. Qualcomm also skipped uop cache.

uop made sense with 32-bit support because the 32-bit ISA was so complex (though still simple compared to x86). Once they went to a simplified instruction design, the cost to decode every single time was lower than the cost of maintaining the uop cache.
by commakozzi | 2025-08-26 18:19:34+00:00
> Apple purposely make it so after 3 new versions of the OS you cannot upgrade the OS on the hardware any further

"oh a post about Apple, let me come in and share my hatred for Apple again by outright lying!"

As stated already, macOS 26 runs on the M1 and even the 2019 Macbook Pro. So i think i know where you got the "3 new versions" figure, and it's a dark and smelly place.
by ecshafer | 2025-08-26 18:19:51+00:00
The cost of assets (especially housing, schooling, and health care) is a huge problem, and your example is a poignant one. More funding could sway a few people in that pipeline to go towards semi-conductors, but the majority of workers aren't Jane Street quality, they are technicians and engineers doing lots of highly skilled "grunt" work.

Personally I think the other half of the problem, Big Tech paying so much might be solving itself right now, excepting really only the very very top.
by GuinansEyebrows | 2025-08-26 18:20:11+00:00
> Ratcheting the expiration down to 47 days is an effort to force everyone to use automation, which makes no sense for small hobby sites.

you make it sound like setting up automated renewals is an onerous process. IME it takes about the same amount of time to set up the automation according to the directions as it does to manually renew the certs with an ACME client. the only difference is you're pasting a command into a crontab/timer instead of directly into your shell to execute.
by hinkley | 2025-08-26 18:20:23+00:00
Expecting it to operate most of the time is a safer bet than expecting it to have a peak output that’s substantially higher than the average. It’s be smart to try to align it with power usage, but in truth it’ll lag behind peak water usage by however long it takes to top off the tanks. I don’t know when that is but I would suspect before morning rush hour.

Probably this thing peaks at 120-150KW which isn’t going to fix the grid.
by krunck | 2025-08-26 18:20:41+00:00
So let me get this straight:

1. I take a shower and produce non-salty waste water

2. That waste water and brine from a desalinization plant can be used in this plant.

3. The result is concentrated waste water and less salty brine and some power

4. The power can be used to (partially) power the desalinization plant produces fresh water from sea water and brine.

5. I get fresh water for my shower.

And the diluted brine from step 3 goes to the sea? Or can it be run through the desalinization plant again? Does concentrating the waste water in step 3 also help with the eventual treatment of it
by timr | 2025-08-26 18:20:53+00:00
The words you're looking for are "substantial transformation" [1].

Exporters in country A (with high tariffs on exports to USA) ship partially completed products to country B (with no/lower tariffs to USA), and then do some manufacturing step. Country B then exports completed products to USA.

China was doing this extensively via Mexico under the USMCA [2]. It's not a matter of debate.

[1] https://www.trade.gov/rules-origin-substantial-transformatio...

[2] https://www.youtube.com/watch?v=5i3Y14TNqCI
by encom | 2025-08-26 18:20:54+00:00
I'll echo all the praise from other posters, and offer one tiny bit of criticism: I don't like the motion damping (or whatever it's called) when panning/zooming around. It feels like wading through mud. I'd prefer it much reduced, or removed entirely.

EDIT: From 12/1989: "Will Clock Speeds Top Out at 50 MHz? An issue that computer designers can't seem to agree on is the ultimate potential speed limit of microprocessor clock rates. The more conservative argument, put forth at the Microprocessor Forum by Microprocessor Report editor Michael Slater and several other conference speakers, maintained that clock speeds will top out at about 50 MHz[...]"
by myrandomcomment | 2025-08-26 18:21:49+00:00
The paths on the network with the MLAG is NOT likely the issue. There is a serialization delay different between the NICs in the NTP servers and switches. 100M takes more time then 1G which takes more time then 10G which takes more time then 40G. Also the UI kit is store and forward (not sure on the 10G but the desktop one is) switching and the Arista kit is cut thought (at around ~500 byte packets IIRC). The end to end paths are not the same given the link speed difference and that is the source of the variations. The MLAG hashing is in hardware and will not have an effect, also IIRC you can set the LAG hash to be SRC/DST on both L2 and L3 even on a L2 link.
by delusional | 2025-08-26 18:22:02+00:00
Can we try to not fall victim to this sort of "us or them" rhetoric. It's obviously exactly what this is being framed as officially, but it's way worse than that.

Yes, the the cost of (at least) some foreign workers is that the jobs they had creating good exported to America will go away. That's true. The trade-off though isn't just that the Americans don't get their stuff. The real trade off is that the good those factory workers buy (whether they be physical or immaterial, cultural or financial services) will not get bought. Americans making those good will therefore ALSO be out of a job.

In the end, nobody gets what they want and everybody loses employment. It's a lose/lose for everybody involved.