MurphyA/hacker-news huggingface dataset:
We Tried Helping Medical AI Startups Get Diverse Data. Here's What We Learned
by mehashim | 2025-07-11 17:44:12+00:00
I’m a medical doctor and founder of a small startup called Craniolabs. A month ago, my cofounders and I started working on a painfully obvious problem in medical AI: the lack of diverse, high-quality, ethically sourced medical imaging data, especially from underrepresented regions like Africa, Asia, and the Middle East.

Everyone in the field talks about bias in datasets, but very few seem to be solving it at the root. So we tried.

We signed memorandums of understanding with hospitals in Egypt and Dubai. We got access to radiology departments and de-identified DICOM archives. We partnered with radiologists. We integrated NVIDIA MONAI to streamline annotation. And then… we reached out to over 30 diagnostic AI startups who we thought would jump at the chance to access better data.

Almost no one replied.

Some opened our emails 3–4 times. A few asked for more info. One or two made it to pricing discussions. But the reality is: most teams either weren’t ready to buy, didn’t have budget, or were hesitant to engage in anything that looked operational.

Here’s what we learned: • Most diagnostic AI startups are resource-strapped, even if well-funded • Everyone wants clean, diverse data, but no one wants to manage the plumbing • Many are still stuck using NIH ChestXray or CheXpert and don’t trust third-party data easily • Even at small scale, hospitals need very clear legal, ethical, and financial frameworks to move data

We’re now restructuring toward a subscription-based model with ready-to-use curated batches, compliance built in, and optional annotations. But the lesson stuck: getting the first few customers is way harder than building the product.

Curious if others here have faced something similar, whether in healthcare, infra, or AI. If you’re building in this space or just have thoughts, I’d love to hear how you’d approach this.

(More about what we’re doing at: https://craniolabs.tech)
by jerryzhang66 | 2025-07-11 17:44:45+00:00
I had some small business adventures before, some good result, some not, but overall not a serious businessman or startup person. So I really wonder about this question...though about tech part, I kind of believe in my design of the model/system.

The info of the project: toCommon, an experimental and ambitious project aimed at reducing vocabulary complexity and improving the efficiency of large language models (LLMs). Though built upon a series of theoretical hypotheses, this repository lays the foundation for a potential startup venture pushing the boundaries of LLM design, training, and inference.

"Now Model for DenseGroupAttention is ready to train on, at same time, the edit system for Simple-Word Compound Substitution is in develope"
by georgeecollins | 2025-07-11 17:44:45+00:00
I definitely doom scroll hacker news and feel bad when I lose karma. But on the plus side I only engage with it when I choose to and its easy to set aside.

I read things and I think: "I have an experience I want to relate!" But I am trying to take a breath more and realize people aren't really that interested in my opinion. I am trying to be at peace with that in general.
by suby | 2025-07-11 17:45:16+00:00
Yes, Medicare too. Unless Congress intervenes, Medicare providers will see about a 4% cut every year starting next October. The new law's deficit boost triggers automatic sequestration cuts across the board each year for ten years.

Total 10 year cut: $~490 billion

Source: https://prospect.org/politics/2025-07-03-republicans-cutting...

The source is clearly biased (sorry), but I believe it's accurate on the numbers.
by zackangelo | 2025-07-11 17:45:36+00:00
Typically a combination of expert level parallelism and tensor level parallelism is used.

For the big MLP tensors they would be split across GPUs in a cluster. Then for the MoE parts you would spread the experts across the GPUs and route to them based on which experts are active (there would likely be more than one if the batch size is > 1).
by dogma1138 | 2025-07-11 17:45:42+00:00
Other than the cost of raising children that’s how it worked until the 90’s. I don’t know what happened I still remember I was in shocked when the school called social services on my sister when they found her 8 year old was alone with her 13 year old in the early to mid 2000’s at home after school.

I don’t know what happened but we’ve started treating children like they are made out of glass and it doesn’t feel really like the threat landscape is any different.

I used to walk from school and play outside until dark every day and everyone else was exactly the same.
by Salgat | 2025-07-11 17:45:54+00:00
BTC has occasionally obtained community driven patches by distributed consensus rather than a centralized approach (as recently as 2021 with the Taproot soft fork). When Quantum Computing finally becomes a threat to BTC, there will almost certainly be a distributed consensus to update the protocol again. Now what happened with Ethereum could be argued as not so decentralized since the organization (Ethereum Foundation) has extremely strong political influence over the corporations that support it.
by hengheng | 2025-07-11 17:46:00+00:00
I was tempted to do that with my first-gen Intel MacBook because it just wouldn't run quiet when idle, that is until I discovered by how much I could undervolt that chip with a random tool that I could just download. I believe I went from 1.26V to 1.03V, or at least these are the numbers still etched into my brain.

Ratio of the squares of those numbers is 2/3, and so the laptop was certainly quiet without having to open it up. But I was surprised at Intel's product back then.
by klik99 | 2025-07-11 17:46:10+00:00
I suspect by "anybody" they meant anyone outside of the "relatively small but healthy sector", and therefore competitors such as Epic or GOG wouldn't count. Outside analysts think of games as a subset of tech and that big tech companies would merely need to turn the eye of sauren towards games and they could conquer the market.

But outside analysts are wrong and completely misunderstand the games industry, see https://www.linkedin.com/posts/ethanevansvp_as-vp-of-prime-g...
by shadowgovt | 2025-07-11 17:46:13+00:00
It is interesting to me that GraphQL would be in "the swamp of POX," mostly because personal experience was that shifting from hand-built REST to GraphQL solved a lot of problems we had. Mostly around discovery and composition; the ability to sometimes ask for a little data and sometimes a lot at the same endpoint is huge, and the fact that all of that happens under the same syntax as opposed to smearing out such controls over headers, method, URI, and query params decreased cognitive load.

Perhaps the real issue was that XML is awful and a much thinner resource representation simplifies most of the problems for developers and users.
by bunderbunder | 2025-07-11 17:46:16+00:00
I worked at a place that had a really great coding standard for working with exceptions:

1. Catch exceptions third-party code and talking to the outside world right away.

2. Never catch exceptions that we throw ourselves.

3. Only (and always) throw exceptions when you're in a state where you can't guarantee graceful recovery. Exceptions are for those exceptional circumstances where the best thing to do is fail fast and fail hard.
by ErrorNoBrain | 2025-07-11 17:46:16+00:00
someone made a youtube video not too long ago (i think was that guy who made the 3rd party ssd upgrade kits?) he said that apple uses a special type of thermal paste... not that its some super awesome unique product, it's just that its not a paste in the typical sense, like you'd use on a GPU or CPU. It's more like a "putty".
by imilk | 2025-07-11 17:46:53+00:00
Well we have hosted 10 small business WP sites per $10 DigitalOcean droplet for the last decade. There are not additional plugin costs on any of them. And there has been no real maintenance needed.

I'm not saying WP is great. Taking over a WP project from someone else can be daunting in tech debt and weird choices. But in terms of having a simple brochure website for businesses that get < 10k weekly visitors, it's pretty quick, cheap, and easy.
by bicepjai | 2025-07-11 17:47:02+00:00
Random Thought: One perspective on how adtech could evolve. I can easily see how new adtech is going to evolve given every one uses llms for search and finding answers. 1. Businesses will create content that is llm friendly. 2. Big training houses (BTH) could charge for including these content when fine tuning. The information and brand will naturally occur when people interact with these systems. 3. BTH could create a subscription model for releasing models overtime and charge for including same or new content.

FYI: I do not want this to happen. The llms will not be fun to interact with and also may be this erodes its synthetic system just like humans with constant ads
by arp242 | 2025-07-11 17:47:03+00:00
> What about Fujitsu? Why can't the government make Fujitsu pay for the destruction caused by their shitty software?

Because the software didn't cause it.

Look, by all accounts the software was/is a piece of piss, but what made it such an egregious scandal is how the Post Office leadership dealt with things. There was really no good reason for that to happen. They just ignored reports of problems (proper reports written by auditors, not vague rumours). They lied to postmasters by saying that no one has problems (when, in fact, there were hundreds of people). Lots has been written about all of this and I won't repeat it all here.

So I must object to the phrasing of "caused by their shitty software". Of course lots can be said about the failings of the software itself and Fujitsu also lied and covered their tracks so they are not entirely blameless. But they emphatically did not "cause" any of this: it was the Post Office leadership who primarily caused this mess.

Lots of things go wrong in the world, lots of things are defective. What often matters the most is not so much the mistake or defect itself, but what the response to that is.
by lanfeust6 | 2025-07-11 17:47:11+00:00
> But the tldr is that committing suicide aligns with an active criminal/immoral act, while dying by suicide is a factual cause of death with many possible causes.

The projections are doing the work here. Colloquially today what's understood is that "commit" merely means they did the deed. People can judge that to be immoral or not regardless; most people don't, except through the lens of religion.

They might judge it to be the wrong choice, as I surely do, and I don't think it helps to diminish agency as though suicide is an inevitability following any given circumstance.
by jackdoe | 2025-07-11 17:47:13+00:00
I do use fast forward :) just not a lot, but also really like cassettes that two good songs happen to be on the opposite sides of each other.

I am using 'bored' quite loosely, I mean allow yourself to not be constantly engaged, the content creators, the algorithms, the advertisers all are trying to keep me at this extreme state so that I could be sold. The bar is really high, in order to be patient I had to re-learn how to not be engaged all the time. Some times I think of nothing, but most of the time I am having fun with stuff either real or not.

PS: yea I do have ocd, my bored or patient probably mean different things to other people
by TimorousBestie | 2025-07-11 17:47:15+00:00
> These are going to be in places that are not heavily touristed even by other Americans. You're talking about places in the deep south; or in some survivalist community in Wyoming/Montana/etc. Not in Miami, Chicago, Los Angeles, etc.

It is really hard to dispute the myth that “America” only consists of a few large cities, à la Death Stranding. Unfortunately, the whole country is not as enlightened as LA, SF, and NYC.

International tourism is also not limited to these cities. NPS alone attracts millions each year. Although, I understand the fees for foreign visitors is increasing soon.
by olalonde | 2025-07-11 17:47:20+00:00
> though 20 blocks were rolled back on at least 2 occasions

Do you mean because of the bugs mentioned earlier or during the normal course of operations? Curious to read more about that.

> Regarding forks, there was BCH, BSV, etc. - those were not programming errors.

That's a different kind of "fork" though and those are arguably not Bitcoin. They're basically just competing cryptocurrencies that happened to use an existing blockchain to get started.
by wkat4242 | 2025-07-11 17:47:22+00:00
No but it's kinda passive aggressive isn't it? It's built on the belief that having religion is the standard.

Also, many of these staps make no sense.

I don't believe in higher powers and I don't want to humbly beg them to remove my character flaws. If I want those removed I have to do it myself.

Some of the steps make some sense but there's way too much senseless groveling in there.
by nickelpro | 2025-07-11 17:47:24+00:00
I recommend you read the report. The charges were brought solely on the claimed accounting shortfalls with no further evidence that the postmasters and sub-postmasters did anything wrong, not even an attempt to discover where the money had gone or anything resembling forensic accounting that would be required in similar US cases.

In the most shocking case, with Martin Griffiths, there were attempts to hold him responsible for robbery loses he had absolutely nothing to do with:

> On 2 May 2013 a robbery occurred at the Post Office which resulted in a net loss to the Post Office of £38,504.96, which was reduced to £15,845 after some of the money was recovered. Mr Griffiths was injured during the robbery; he was present in the branch when it occurred. The Post Office Investigator advised the Post Office that Mr Griffiths was partly to blame for the loss sustained by the Post Office and that he should be held responsible for part of the loss. [1]

Such a claim wouldn't even be colorable in most jurisdictions.

I disagree that anything similar could happen at this scale in the US or France. Individual cases might not be handled perfectly, but this is a systemic miscarriage of justice where at every turn individuals were prosecuted without any evidence of individual wrongdoing. It was believed money was missing, no attempt was made to discover how it went missing, and the post-masters were held responsible without further inquiry. The legal system upheld these non-findings as facts and convicted people based upon them.

[1]: Post Office Horizon IT Inquiry, 3.49
by jerf | 2025-07-11 17:47:26+00:00
I'd expect this is just the lamppost effect and we'll start seeing lots of these. It means there's no great need to chase any particular one of them, we can almost certainly wait until we're ready, then pick one that is convenient at the time.

It also means that "Oumuamua is an alien craft!" will almost certainly join in the ignoble legacy of "thinking the first instance of a new thing must be ALIENS" once we've detected hundreds of these (or more, depending on how sensitive we can get). You'd really think we'd be over this by now, but apparently not.
Show HN: Reactions
by abjectai_42 | 2025-07-11 17:47:33+00:00
Blog post on the research on why we made Reactions.

I am super excited to announce the launch of Reactions!

Reactions is a fun and visual way to express emotions and reactions in group settings, such as game nights, casual conversations, or family dinners.

Here is how to use them: https://reactionsdeck.com/2025
Show HN: RULER – Easily apply RL to any agent
by kcorbitt | 2025-07-11 17:47:36+00:00
Hey HN, Kyle here, one of the co-founders of OpenPipe.

Reinforcement learning is one of the best techniques for making agents more reliable, and has been widely adopted by frontier labs. However, adoption in the outside community has been slow because it's so hard to implement.

One of the biggest challenges when adapting RL to a new task is the need for a task-specific "reward function" (way of measuring success). This is often difficult to define, and requires either high-quality labeled data and/or significant domain expertise to generate.

RULER is a drop-in reward function that works across different tasks without any of that complexity.

It works by showing N trajectories to an LLM judge and asking it to rank them relative to each other. This sidesteps the calibration issues that plague most LLM-as-judge approaches. Combined with GRPO (which only cares about relative scores within groups), it just works (surprisingly well!).

We have a full writeup on the blog, including results on 4 production tasks. On all 4 tasks, small Qwen 2.5 models trained with RULER+GRPO beat the best prompted frontier model, despite being significantly smaller and cheaper to run. Surprisingly, they even beat models trained with hand-crafted reward functions on 3/4 tasks! https://openpipe.ai/blog/ruler

Repo: https://github.com/OpenPipe/ART
by carstout | 2025-07-11 17:47:41+00:00
Unfortunately the "its rare" isnt true. it is more common now than it was back in the horizon days. It also isnt necessarily expensive since you can apply for costs with the default being for it to be paid (unless good reason not to). As such whilst its not an option for the average person who cant afford the upfront cost it is very practical for large businesses especially if they engage in it often and hence can stand up a department for it.

Its one of the offerings from TM-Eye aka one of the "private police forces". https://tm-eye.co.uk/what-we-do/private-prosecutions/

It is an actual example of a two tier justice system since those who can afford the private prosecution skip the queue for the public system but will still normally have the taxpayer pay for it.

There is currently a consultation underway as per below article which, incidentally, mentions a more recent dubious example of private prosecutions which got slapped down.

https://www.gov.uk/government/consultations/oversight-and-re...
$300/month Grok. What would you do with this?
by paulpauper | 2025-07-11 17:47:43+00:00
The most expensive Grok package is $300/month, which was released yesterday as part of the Grok 4 launch. I am thinking this can be an insanely good value if you know how to use it, or a wase of money. What would be a good use for this? What use would justify the $300? The low-end Grok can already do a lot. What are some use cases to justify paying so much.
by Vegenoid | 2025-07-11 17:47:47+00:00
> Some glitches were of their time and wouldn't occur these days, e.g. malfunctions in resistive touch screens that caused random clicks on POS screens to occur overnight

I think there’s still a lesson to be learned here about computers needing to be locked when not in use. I find it utterly bizarre how many experienced technical employees will leave their computer unlocked when they step away from it for extended periods of time.
by itopaloglu83 | 2025-07-11 17:48:57+00:00
The Original iPhone didn’t have any apps and Apple later created their own ecosystem with an end user agreement which supersedes the ads.

The digital market should be regulated for sure but what’s happening is a bunch of companies who are in the digital market (and not regulated themselves) exploiting the public sentiment and the regulatory processes.

Spotify and others fail to mention that they were able to access billions of Apple customers without paying a single dime to Apple initially which is unheard of in business relationships.
by ghostly_s | 2025-07-11 17:49:09+00:00
Yes, my story with btrfs is quite similar- used it for a couple years, suddenly threw some undocumented error and refused to mount, asked about it on the dev irc channel and was told apparently it was a known issue with no solution, have fun rebuilding from backups. No suggestion that anyone was interested in documenting this issue, let alone fixing it.

These same people are the only ones in the world suggesting btrfs is "basically" stable. I'll never touch this project again with a ten foot pole, afaic it's run by children. I'll trust adults with my data.
by lanfeust6 | 2025-07-11 17:49:33+00:00
That words matter is why I'm in opposition, as this diminishes agency in people.

Today I would say that framing suicide as "immoral" in secular society is banal and has no traction, but most, excepting certain circumstances, would suggest it is a bad choice. That surely follows if you as well as I would try to talk an able person out of suicide.

I don't think it helps to diminish agency as though suicide is an inevitability following tough circumstances. That's the message I am getting from the euphemism treadmill game, and I reject it.

The message should be that you can go through hell and recover, and you still have a choice. And granted there's always nature vs nurture; just as we are not entirely the product of our environment, the environment does shape us. But it's not all-or-nothing.
by mosburger | 2025-07-11 17:50:01+00:00
Last year I underwent treatments for my treatment-resistant major depression using Ketamine. It was a clinical setting, where you'd get wired up to blood pressure, pulse-ox, and other monitors while you were monitored by an RN via video camera. This was IV Ketamine, so not the inhalants that are available now. According to the clinic, the inhalants (which they also offered) are also generally less effective than IV, and the IV was safer in my case because I have other medical conditions where being able to "shut it off" was a good thing - you can turn an IV off, but once you inhale, you're on your own.

So... this clinic was not entirely unlike what you're proposing w/ DMT.

FWIW, the results were incredible. I was effectively "cured." But unfortunately my insurance changed, and it became no longer covered, and I couldn't afford the $2000 every six weeks for the treatment anymore. And it's not super convenient to take two hours off from work to go to the trip-sitter's to get the treatments.

I hope that they figure out what it is in psychadelics that make them effective at treating stuff like depression and PTSD and make it more accessible because it seems like there's so much potential there.

(Also: fuck Elon Musk for making Ketamine a punchline)
by anonfordays | 2025-07-11 17:51:04+00:00
Garcia doesn't get the protections afforded by the Seventh Amendment:

Deportation is a civil treatment. It's one of the actions the government can use when you violate civil immigration laws:

The Court added that an alien being removed by the government is not being “deprived of life, liberty, or property” and that “the provisions of the Constitution securing the right to trial by jury and prohibiting unreasonable searches and seizures and cruel and unusual punishments [therefore] have no application. That is also why federal immigration officers do not need a warrant issued by a judge before arresting and detaining aliens and why aliens are not entitled to be advised of their Miranda rights or to the assistance of a government-appointed lawyer during their deportation proceedings.

https://www.heritage.org/border-security/report/due-process-...
by nivertech | 2025-07-11 17:51:05+00:00
he wrote

> The Rube Goldberg of PoW isn't just for show, it's a protection from Sybil attack

he cherry picked PoW

no, Nakamoto-style consensus is not the same thing as PoW, or even PoW+LCR, not even the same thing as Bitcoin consensus.

Nakamoto-style consensus simply means that we're doing a leader election, and the leader does the transaction validation (aka mining a block in Bitcoin-speak).

The novelty of Nakamoto-style consensus is how we're doing this leader election, i.e. using PoW, PoW+LCR, PoS, PoET, PoA, Proof-of-X, etc.