MurphyA/hacker-news huggingface dataset:
by jacobgkau | 2025-07-18 23:27:10+00:00
I started getting emails from Cigna about Omada after switching over to them last year. They pitch it as something you can sign up for to get health coaching. They (or their AI, soon if not already) provide that by sending you some "free" sensors (scale, pedometer, etc) and collecting lots of health information.

Searching the web shows that Cigna forces some patients to use this program in order to receive coverage for certain conditions. They're likely saving all the info collected through it in order to use it to deny you coverage if they can at all make an argument that something was caused by your lifestyle, was pre-existing for a certain amount of time, etc-- at least, that's the vibe I got from researching it.
by puzzlingcaptcha | 2025-07-18 23:28:25+00:00
The uridine modification was intended to reduce immunogenicity of mRNA - some of our immune cells have pattern-seeking receptors in the TLR family that recognize ssRNA and dsRNA. The presence of modified uridines throws this pattern recognition off. (https://doi.org/10.1016/j.jconrel.2015.08.051)

The modifications to increase mRNA half-life concerned mostly the caps and poly(A) tail. But even with those the persistence was in the range of days (sort of depending on how sensitive a method you picked).
by ASalazarMX | 2025-07-18 23:28:40+00:00
The new Steam UI was incredibly bloated at the start, it was frequent (in my experience) for it to force close because it wouldn't fit in RAM along with the active game. It got better, but I'm still not loving it.

Maybe I'm prejudiced to React and its variants, because I have never used a React app I liked, just React apps that are useful despite their shortcomings.
by sugarpimpdorsey | 2025-07-18 23:28:41+00:00
This makes no sense.

Microsoft uses separate CAs (read: separate root certificates) to sign Windows vs Linux bootloaders.

Both CAs have to be trusted. They could also, in theory, be revoked separately.

There is no reason the "third party" CA couldn't be run by Red Hat. It's done by MS out of convenience.
by didibus | 2025-07-18 23:28:43+00:00
Not necessarily, but I guess it depends how you define "dependency".

For example, it might be partial ordering is needed only, so B doesn't fully depend on A, but some parts of B must happen after some parts of A.

It also doesn't imply necessarily that B is consuming an output from A.

And so on.

But there is a dependency yes, but it could be that the behavior of the system depends on both of them happening in some partial ordering.

The difference is with asynchronous, the timing doesn't matter, just the partial or full ordering. So B can happen a year after A and it would eventually be correct, or at least within a timeout. Or in other words, it's okay if other things happen in between them.

With synchronous, the timings tend to matter, they must happen one after the other without anything in-between. Or they might even need to happen together.
by asveikau | 2025-07-18 23:29:19+00:00
I run several machines at home with NFS $HOME and I usually don't notice. I'd say with a good network and as long as you're not stress-testing difficult cases like parallel writes to the same data from multiple machines, the average usability of NFS is actually very good.

I did have a hell of a difficult time once with intermittent failures from a poorly seated network cable.
by homebrewer | 2025-07-18 23:29:23+00:00
Some of those packages (like Brave) are maintained by original developers, it depends on the package.

Most aren't, but it's trivial to review changes to packages (all good AUR helpers show the diff on upgrades, an 99% of time the changes are hash and version, nothing else).

So you only need to check the package once, which the documentation reminds you to do about fifty times. Otherwise — play stupid games, win stupid prizes.

If the package has any popularity at all, you will get lots of paranoid users who will eat you alive and report to Arch maintainers right away if you do anything suspicious, try to link a binary from some weird website instead of the upstream URL, or even just omit the GPG signature verification key when it's available.
by miggol | 2025-07-18 23:29:33+00:00
I don't want to defend Django here, surely this should be categorized as a bug. But on the other hand, for this situation to come up you have to be the following:

- The kind of person to dive into the schema and worry about an unnecessary index

- Smart enough to heed Django's warnings and use `Meta.UniqueConstraint`

- Dumb enough to ignore Django's warnings and not use `Meta.Indexes`

I think it's funny that the kind of dev that 100% relies on the ORM and would benefit from this warning would probably never find themselves in this gritty optimization situation in the first place.

That being said, I enjoyed the article and learned something so maybe I'm the target audience and not them.
by carrodher | 2025-07-18 23:30:10+00:00
The complete history of Bitnami container images has been copied to the "bitnamilegacy" repository. New tags will continue to be synced there until August 28th. After that date, "bitnamilegacy" will no longer receive updates, and images in the mainline "bitnami" repository will begin to be removed over a period that may take up to two weeks.

Once the cleanup is complete, the mainline "bitnami" repository on DockerHub will contain only a limited subset of Bitnami Secure Images (at this moment available at "bitnamisecure"). These are hardened, security-enhanced containers intended for development or trial use, providing a preview of the full feature set available in the paid offering.

- Bitnami: https://hub.docker.com/u/bitnami - Bitnami Legacy: https://hub.docker.com/u/bitnamilegacy - Bitnami Secure Images: https://hub.docker.com/u/bitnamisecure
by alexjplant | 2025-07-18 23:31:53+00:00
I wrote a book report on a biography of Bill Gates when I was 7 or 8. It contained a youthful anecdote about his mother calling him on the house's intercom and him replying after several ignored attempts that "[he was] busy thinking. Maybe [she] should try it sometime!"

An intercom? In a house? So that your mother didn't have to repeatedly yell up the stairs to your brother that food is on the table? Sure sounded like rich person stuff to me.
by benjiro | 2025-07-18 23:32:37+00:00
Unfortunately, cash is slowly getting phased out.

Try buying a second hand car and you want cash from the bank. Used to be very easy, but now you need to declare what your spending your money on.

You sold your car. O, its over 7 or 10k, well, this is getting reported to the local IRS. Where is that cash coming from, questions, questions?

Over here they are even cracking down on stuff like ebay, amazon because some people run a business on those sites and do not report the taxes. Result: If you make over 3k in the year on ebay, you need to provided your tax number, or ebay closes your account. And above 3k, it get reported to the IRS.

But wait, what happens if your a foreign national from some specific Asian countries and want to open a bank account? Refused, refused, refused... But you need a bank account for a lot of basic things. Well, tough luck. Lets not talk account closing issues.

And that is the EU, and just normal people. Nothing tax evasion, guns, or whatever. Just everybody putting up umbrella's to be sure, not understanding that when everybody does it, it really screws with people.

They are going crazy with this over regulation. Yes, i understand you want to fight black money but the people who get the big amounts will have ways to hide it. Your just hurting the normal people wanting to know what everybody is doing exactly with every cent.

You see this gradual effort to slowly phase out cash. Cashless payment are getting encouraged, cash withdrawals cost your money more and more, more questions regarding origins (so you say f it, and use bank deposits with release approvals).

Its not a surprise that we seen the increase in cryto usage (and the efforts of governments to control that also).
by sugarpimpdorsey | 2025-07-18 23:33:04+00:00
> as if the Linux ecosystem had any leverage at all on PC manufacturers…

Linux has 63% of the server marketshare, which is where Secure Boot and the whole chain-of-trust has utmost importance. Of course they have leverage.

Do you think overall Secure Boot is more important in the context of securing your bank's servers, or some porno jack machine throwaway laptop?
by ChuckMcM | 2025-07-18 23:33:13+00:00
EDIT Note: Sharp eyed commentators pointed out I misread the table, which makes the economics better. I had originally 3% but updated it to 10%

Hmmm, mercury-198 is 10%[1] of mercury, of which in 2022, China was the top supplier at 2000 tonnes[2], so 200 tonnes of that is the "good stuff". Not a lot of easy access to open data on Mercury spot prices, this source[3] has it at $2000 per flask which is 76 lbs or 34.5 kg. Using our 10% number that's 7.6lbs per flask. Which if you convert that into 7.6lbs of gold you can sell it for a bit over $300K. So not too bad. Presumably a lot of currently shut down mercury mines might start up again, but you're adding 9 tonnes of mercury 'waste' to get your 1 ton of Hg-198. The cost of disposing that might be challenging. If you could sell it back at the current spot price for mercury by flask it would be great, but with all the extra supply I think the price might go down? Which kind of helps your economics until someone only puts mercury on the market that they have already removed the HG-198 from. Being vertically integrated with your own mercury mines and reserves would be good here.

The thing I don't get is why fusion? I mean you can get fast neutrons out of fission too, what sort of gamma flux do you need to generate Hg-197? Can the LHC do this trick? I mean seriously can you put a beaker of mercury in the beam path and transmute 3% of it to gold? Seems like a way to get budget for more experiments right?

[1] https://chemlin.org/isotope/mercury-198

[2] https://worldpopulationreview.com/country-rankings/mercury-p...

[3] https://www.metalary.com/mercury-price/
by jacobgkau | 2025-07-18 23:33:16+00:00
My NP would tell me "nothing to worry about" whether she knows what's going on or not, but that's beside the point.

GP wasn't asking what they should personally do. They were asking how the doctor would screen for it. (The truth is, the doctor can't/won't-- an annual MRI on every otherwise healthy person, for example, would be prohibitively expensive with how MRIs are currently set up-- and as another commenter pointed out, findings from those can be just as easily ignored or put off until it's too late.)
by miki123211 | 2025-07-18 23:33:22+00:00
Because white collar salaries are extremely high, which makes the services of white collar workers unavailable to many.

If you replace lawyers with AI, poor people will be able to take big companies to court and defend themselves against frivolous lawsuits, instead of giving in and settling. If you replace doctors, the cost of medicine will go down dramatically, and so will waiting times. If you replace financial advisors, everybody will have their money managed in an optimal way, making them richer and less likely to make bad financial decisions. If you replace creative workers, everybody will have access to the exact kind of music, books, movies and video games they want, instead of having to settle for what is available. If you automate away delivery and drivers (particularly with drones), the price of prepared food will fall dramatically.
by zer00eyz | 2025-07-18 23:33:57+00:00
> Apollo program: 4%

More than a decade long. The technology and industry here was broadly shared. They did things like highjacked bra manufacturers to make space suits.

> Railroads: 6% (mentioned by the author)

We're still using this investment today.

> Covid stimulus: 27%

The virus that was killing us the fizzled is probably not the best example... Only arguments will ensue if I even attempt to point thing out in this one.

> WW2 defense: 40%

I mean Russia made its last lend lease payment in 2006. It lead to America dominance of the globe. It looks like an investment that paid it self off.

How much of the hardware spend on AI is going to be usable in 5years?

There are some deep fundamental questions one should be asking if they pay attention to the hardware space. Who is going to solve the power density problem? Does their solution mean we're moving to exotic cooling (hint: yes)? Have we hit another Moores law style wall (IPC is flat and we dont have a lot of growth left in clock, back to that pesky power and cooling problem). If a lot of it is usable in 5 years thats great, but then the industry isnt going to get any help from the hardware side and thats a bad omen for "scaling".

Meanwhile capex does not include power, data, constables or people. It may include training, but we know that can't be amortized. (how long does a trained system last before you need another, or before you need a continuation/update).

Everyone is going after AI under the assumption that they can market capture, or build some sort of moat, or... The problem is that no one has come up with the killer app where the tech will pay for itself. And many in the industry are smart enough not to try to build their product on someone else's platform (cause rug pulls are a thing).

"AI" could go the way of 3d tv's, VR, metaverse, where the hype never meets up with hope. That doesn't mean we wont get a bunch of great tooling out of it. It is going to need less academics and more engineering (and for that hardware costs have to drop...)
by rscho | 2025-07-18 23:34:32+00:00
Apart from the likely technical infeasibility of your idea in today's society, this would require a humongous and diversified population sample to be meaningful (your 'heterogeneous bits'). This follows directly from the complexity of metabolic pathways you wish to analyze. Socially, you'll only be able to achieve that by not asking your sample for consent. Otherwise you'll have a highly biased sample, which could still be useful but for severely restricted research questions.
by ASalazarMX | 2025-07-18 23:35:59+00:00
I'm hesitant to comment further seeing I've attracted the ire of some people with my comment, but anyway. I too used Arch out of curiosity about like ten years ago, during the first "Arch, BTW" memes, and found it too unstable, but that's expected from a rolling release: update too soon or too late, and something could break. I didn't mind, as it was a hobby.

Eventually, I got more busy and had less time to tinker, so I migrated to Ubuntu LTS, which has some small warts, but has needed practically null babysitting compared to Arch. I was surprised when the Arch memes resurfaced this year, but that's the only growth I've seen. None of my Linux-savvy peers use Arch, BTW.
by ChuckMcM | 2025-07-18 23:36:22+00:00
This is not a problem for finance bros, they would sell a discounted note that gave you "ownership" of the gold in 17 years at some discount on the current spot price of gold. So you'd get these things that 'mature' in 17 years and you know their going to be worth whatever the spot price of gold is then, so it becomes a simple problem of pricing the risk that gold will be worth something in 17 years (people by gold futures all the time which this basically is).
by csours | 2025-07-18 23:37:14+00:00
Whatever policy we pursue, whatever decision we make, is not forever (at a society level).

When people die, we change policy. When people feel like they cannot get the treatment they need, we change policy.

Unfortunately, this is very complicated and emotionally heavy, and it is much easier to set down the burden on someone else's shoulders, in the form of blame.

We want the FDA to do life critical, complicated and contradictory things, so it's easy to create a narrative that blames the FDA.

The other option besides blame is shared responsibility and humility, but it feels like people are not very good at thinking that way right now.
by Ancapistani | 2025-07-18 23:37:19+00:00
> Because "anti-abortion/pro-life" removes a right from women. Trading the rights of a developed adult for the rights of a hypothetical future person.

Their perspective is that abortion is killing a human being. Given that, it’s entirely consistent.

> What does ancapistanism have to do with it?

Nothing, other than that I was providing some context on where I’m coming from.

> Is there a non-religious reason to be against the right to choose abortion up to 24 weeks of pregnancy?

While religion is certainly a factor for a lot of these people, this question doesn’t make sense to me. Is there a non-religious reason to be against killing any person, regardless of age?

The base difference in perspective is that the other side here believes that the fetus is a human being, with all the rights that come with it.
by krapp | 2025-07-18 23:37:45+00:00
I don't know what your definition of "actual" free speech is but there are certainly limits to free speech even in the US[0].

And those are just explicit limits. Try supporting Palestine on a college campus or mentioning women or gay people in any government funded scientific publication, or finding a book portraying pro-LGBT content in a library or a school curriculum that portrays slavery in a way that "makes white people feel victimized" in the South.

[0]https://en.wikipedia.org/wiki/United_States_free_speech_exce...
by standingca | 2025-07-18 23:37:52+00:00
Or perhaps even routine bloodwork could incorporate some form of sequencing and longitudinal data banking. Deep sequencing, which may still be too expensive, generates tons of data that can be useful for things that we don't even know to look for today, capturing this data could let us retroactively identify meaningful biomarkers or early signals when we have better techniques. That way, each time models/methods improve, prior data becomes newly valuable. Perhaps the same could be said of raw data/readings from instruments running standard tests as well (as opposed to just the final results).

I'd be really curious to see how longitudinal results of sequencing + data banking, plus other routine bloodwork, could lead to early detection and better health outcomes.
by encom | 2025-07-18 23:38:08+00:00
Dane here, and I just don't see the point of using Apple or Google pay. Aside from not wanting American tech interfering in, or data harvesting, my finances, it's not any easier to use. I just touch my card to the terminal and payment happens. Some times, or if the amount is over some limit, I have to enter a pin. I cringe every time I see someone contorting their arm to pay with their watch. It's tech for the sake of tech.

Sincerely, Ted K.
by hopelite | 2025-07-18 23:38:33+00:00
“Heft of EU endorsement.” It’s amazing how Europeans have simply acquiesced to an illegitimate EU imitation government simply saying, “We dictate your life now!”.

European aristocrats just decided that you shall now be subjects again and Europeans said ok. It’s kind of astonishing how easy it was, and most Europeans I met almost violently reject that notion in spite of the fact that it’s exactly what happened as they still haven’t even really gotten an understanding for just how much Brussels is stuffing them.

In a legitimate system it would need to be up to each sovereign state to decide something like that, but in contrast to the US, there is absolutely nothing that limits the illegitimate power grab of the EU.
by tekbog | 2025-07-18 23:38:46+00:00
There's a great old book on this if someone wants to check it: Communicating Sequential Processes. From Hoare. Go channels and the concurrent approach was inspired on this.

I also wrote a blog post a while back when I did a talk at work, it's Go focused but still worth the read I think.

[0] https://bognov.tech/communicating-sequential-processes-in-go...
by JumpCrisscross | 2025-07-18 23:39:04+00:00
> Surely the driver had to know his car did not take over these functions

“Before the crash, McGee had engaged the system that Tesla calls Autopilot, which can steer, brake and accelerate the car on its own.

…

Lawyers for the plaintiffs accuse the company of overpromising what its technology can do in order to sell cars.

…

In 2016, the company posted a video of what appears to be a car equipped with Autopilot driving on its own.

‘The person in the driver's seat is only there for legal reasons,’ reads a caption that flashes at the beginning of the video. ‘He is not doing anything. The car is driving itself.’ (Six years later, a senior Tesla engineer conceded as part of a separate lawsuit that the video was staged and did not represent the true capabilities of the car.)

https://www.npr.org/2025/07/14/nx-s1-5462851/tesla-lawsuit-a...
by benjiro | 2025-07-18 23:39:10+00:00
The problem is not SQLite struggling with databases in GB range. It does that with ease. OLAP requires a different database structure, namely column storage (preferably with compacting / compression / and other algorithms).

That is DuckDB its selling point. You want data analyzing, you go DuckDB. You want oltp you go SQLite. Or combine both if you need both.

Even postgres struggles with OLAP dataloads, and that is why we have solutions like TimescaleDB / postgres plugin. That ironically uses postgres rows but then packs information as column into columns row fields.

That does not mean that postgres is flawed working with big data. Same with Sqlite... Different data has different needs, and has nothing to do with database sizes.
by philipkglass | 2025-07-18 23:40:44+00:00
I think you read that table a little quickly. Mercury-198 is 10% of natural mercury.

According to the paper, you need neutrons of at least 9 MeV to drive the transmutation. Fission reactions don't generate neutrons with energies that high. A proton accelerator can generate high energy neutrons by spallation, but in smaller numbers. It wouldn't be economically viable to do this with accelerator generated neutrons.

The paper shows that neutrons from deuterium-tritium fusion are energetic enough (14.1 MeV) to drive the transmutation reaction, and they're a natural byproduct of a D-T fusion reactor, and adding this extra gold generating step shouldn't compromise the ordinary fuel breeding and power generating operations of a commercial fusion reactor.

So now all they need is a commercial fusion reactor. I say that with tongue firmly in cheek, but also impressed that working fusion reactors (if they ever arrive) can also upend the current gold market.
by Ancapistani | 2025-07-18 23:41:01+00:00
Exactly.

My personal belief is that life begins at conception. As a result, I’m opposed to abortion in all cases.

… but I’m also an anarchist, and therefore believe it is emphatically not the state’s role to make these types of decisions for people.

I don’t think there is a “right answer” here in terms of policy. Some large portion of the people will see it as a violation of their rights no matter how extreme or nuanced the line is drawn.
by ltbarcly3 | 2025-07-18 23:41:48+00:00
They might decide to rewrite an lgpl project, but there is a massive sunk cost. At the point they make the decision the gpl project is less tempting to bring fully in house.

(L)GPL: - Investing $3M to extend. - Would cost $17M and 3 years to re implement to baseline and then extend. - Lose all community development inputs because new solution is fully in house. Permissive: - Investing $3M to extend. - Would cost $0 and 0 years to keep in house and still extend - Keep 100% of community development inputs initially and potentially forever if they are able to extend in a way that avoids conflicts. Can port most community developed features with some effort.

Corporations make decisions 1 quarter and at most 1 year ahead. It's a very hard sell to say "we need to take 3 years and a huge investment to get to where we already are at". It could happen for some very specific, high value technologies where someone at the Sr. Director or VP level is taking a long view , but it would be extremely rare.