MurphyA/hacker-news huggingface dataset:
by _kush | 2025-04-28 05:32:13+00:00
I’m working on LookAway (https://lookaway.app) to help people stay healthier and more productive during prolonged screen time.

My main challenge has been making meeting detection more robust -- it currently uses both mic and camera activity, which led to a lot of false positives. In the next version I’m switching to mic only (the camera caused most of the noise) and I’ve added a way to identify which app is using the mic, so users can exclude non-meeting apps.

I’ve also added plenty of small tweaks throughout to make LookAway even less interruptive. I’m excited for the next release!
by aledalgrande | 2025-04-28 05:32:39+00:00
On a sidenote, I tried to get Codex + O3 to make an existing sidebar toggable with Tailwind CSS and it made an abomination full of bugs. This is a classic "boilerplate" task I'd expect it to be able to do. Not sure if I'm doing it wrong but... a little bit more direct instructions to O4-mini and it managed. The cost was astronomical tho compared to Anthropic.
by fc417fc802 | 2025-04-28 05:34:06+00:00
Depends on what is meant by high strength. Silverware is a fair point that hadn't occurred to me. Handrails is an interesting one but I suspect it's more cost effective to place a thin contact surface on top of something cheap.

The others I'm not so sure about. I think you'd have corrosion issues with water tanks and bacterial issues there are easily addressed by regulating temperature. And why would heat exchangers require particularly high strength? Since when are those a structural component?

In any case as you said electroplating something cheap is probably the way to go.
by xyst | 2025-04-28 05:34:44+00:00
The author here is shoehorning "AI" into the headline to boost views. Quite misleading.

"AI" in this case was used to generate a 3D model of a protein. Literally, something you can grab from Wikipedia — https://en.m.wikipedia.org/wiki/Phosphoglycerate_dehydrogena...

The underlying work performed by the researchers is much more interesting — https://linkinghub.elsevier.com/retrieve/pii/S00928674250039...

They identified a possible upstream pathway that could help treat disease and build therapeutic treatments for Alzheimer’s.

I don’t know about you all but I’m tired of the AI-mania. At least author didn’t but "blockchain" in the article.
Building Personal Digital Twins for Health Optimisation and Drug Simulation
by Melissa_bime | 2025-04-28 05:35:03+00:00
Hi HN,

We’re working on BioReplica, a platform that lets you create a digital replica of your own biology, based on your DNA, medical records, wearable data, and physiological metrics. Why? Right now, if you want to know how a supplement, diet, or exercise protocol will affect you, you usually have to experiment on yourself and hope for the best. No two bodies respond the same way, but personalization is still mostly guesswork. BioReplica is an early attempt to change that. We build a personal biological model, a simulation that lets you test "what if?" scenarios safely before trying them in real life.

Examples:

"If I start taking NMN, will my inflammation markers likely improve or worsen?"

"Would intermittent fasting affect my heart health risk, based on my baseline data?"

"Is this new nootropic likely to interact badly with my genetics or medications?"

Instead of generic advice, you can start seeing predictions based on you, your genome, your health history, your day-to-day physiology.

We’re very early. Right now the simulations are basic, focused mainly on lifestyle and supplement interventions. But over time, the idea is to make it richer, more data inputs, better modeling, higher accuracy.

Caveats:

Biology is still messy, and simulations are probabilistic, not certainties.

The platform isn't diagnostic or a substitute for real medicine (and shouldn’t be).

Getting the modeling right is hard, and we’re very upfront about that. The long term goal is for these replica's to be used for pharma simulations. In clinical trials today, most failures happen late, billions spent, and sometimes only then do we learn that a drug doesn’t work or has hidden risks.

Still, we believe even imperfect simulations, if used carefully, can help people make smarter decisions about their health.

If this idea resonates (or if you see flaws we should be thinking about), we’d love feedback. Learn more on https://bioreplica.ai/landing
by runarberg | 2025-04-28 05:35:10+00:00
I‘m sorry, but I’m not buying it. Other industries have had the technology for a long time to mass produce low quality products which harms their customers, or worse, bystanders. And in many of those cases the harmful production was never allowed on the market because the regulator was proactive and prevented the technology to be sold to consumers. I know those stories aren’t as prominent as the story of leaded gasoline, because stories of harm spread much further than stories of prevented harm. But they do exist, and are numerous.

I also fail to see why we need both regulation and moral behavior from developers. If the regulation exists, and the regulator is willing to enforce it, any company which goes against the regulation will be breaking the law, and stopped by the regulator. We only need the regulation in this case.
by klodolph | 2025-04-28 05:35:26+00:00
Physical interpretation of geometric mean… you have a collection of multiplicative speedups, and some of them apply to any given workload. I think the geometric mean falls out of the resulting statistical distribution in a natural way but I’m sleep-deprived at the moment and can’t write out the math. Like, in this distribution geomean is the median speedup.

Think of the case with two values, 2.00 and 2.42. Decompose it into three speedups… 2x, 1.1x, and 1.1x. The speedup 2x happens with probability 1. Each of the 1.1x speedups happen with probability 0.5. The geomean is 1 2x speedup and 1 1.1x speedup, giving 2.2x.

There are many such decompositions, that one is not unique. Exercise for the reader to show which conditions give you the geometric mean and explain why that is reasonable… I’m terribly sleep-deprived at the moment and this is where I stop.

There is of course no correct choice of mean here, just a bunch of different choices with different interpretations justifying them.
by raybb | 2025-04-28 05:35:27+00:00
LLM document editor using your voice only.

Sounds basic, and it is, but I've yet to find any open source project (let alone product) that does this.

All I want to tap a button, talk to the little guy about how to update my document, and see the changes flow. I guess Claude projects or similar might do this but I'm making it more for friends and family. Current use case is keeping track of a house renovation project going on.
by kavalg | 2025-04-28 05:36:00+00:00
I am working on the sunflower plant density estimation problem. The goal is to be able to estimate the germination rate as early as possible. Farmers benefit from such information, because:

- there are lots of expenses still to be made (fertilizer, pesticide, salaries), which may not be worth it if germination is under certain threshold

- if detected early, there is still time to plant another grain or to fill up the missing plants (requires precision seeders and seeding maps)

- is a very good proxy for yield estimation (farmers often trade futures even before they have harvested)

For the purpose I have created a dataset (a collaboration between my employer and Sofia University) and published it in order to enable scientific collaboration with other interested parties. Still working on the dataset annotations.

https://huggingface.co/datasets/su-fmi/sunflower-density-est...
by jader201 | 2025-04-28 05:36:15+00:00
> Instead of finding an offer after 500 interviews, now you may have to do 400.

Holy cow, is that really how many interviews it takes to get hired these days?

It’s been about 10 years since I changed jobs, and then it took less than maybe 10 interviews.

> For me, getting a master's degree was more useful than getting a bachelor's.

I’m not sure this is the norm. I know very few people that I’ve worked with or have interviewed that have masters degrees. I’ve worked with + interviewed maybe close to 300 SWEs, and probably fewer than 5%, if that, have/had masters degrees.
by platevoltage | 2025-04-28 05:36:20+00:00
I'd love an opportunity to contribute to open source. There have been some small contributions I've made to open source libraries that needed a fix, but nothing major. Come to think of it, I submitted a pull request to Tauri and should probably check if it's approved or not.

I'm always down for networking in person. I don't know how DMing works on here, but my Github username is the same as my handle on here.
Show HN: Cohesyve (Agentic AI to scale e-com brands with data driven decisions)
by arpit_bansal | 2025-04-28 05:36:29+00:00
Hey folks! Excited to share something we've been working on at Cohesyve. Built primarily to serve fast scaling e-commerce brands, Cohesyve does three key things:

(1) Unify reporting across various sales and marketing channels (2) Enable automations across the e-commerce stack (e.g. Stop underforming meta ads automatically) and (3) Identify gaps and opportunities in the business using AI (e.g. prepare a cross platform inventory replenishment plan to better manage inventory)

We're currently piloting with brands in the US and India. Would love to hear your thoughts.
by npoc | 2025-04-28 05:36:41+00:00
And it would go down in value relative to a similar asset offering ideal scarcity with 0 inflation rate.

All roads lead to bitcoin.

BTW. The price/ buying opportunity is fair. Those who buy earlier risk far more than those who buy later. The Bitcoin standard is becoming more and more inevitable everyday.

There'll be more than enough demand for transactions on the base layer to pay for the security. In fact a bigger concern right now is that there will be too much demand for the base layer.
by animeshjain | 2025-04-28 05:37:05+00:00
I develop Chips of Fury, a poker app for playing privately with friends. Currently I am building support for lots of home game variations like pineapple (regular, crazy, lazy), different Holdem variations like Super, reverse, super reverse, blind man's bluff etc and many more. I am thinking about how to implement AI bots for a wide range of variations.
by JumpCrisscross | 2025-04-28 05:37:36+00:00
> how long did it take you to find a study from a country known for driving like new zealand to make this crazy claim?

About five minutes on Kagi. There is a solid global meta analysis [1], but it’s not as simple to read and doesn’t discriminate by the speeding magnitude. So I opted for the cleaner source as it’s more relevant to the question of people who speed so aggressively and often that a judge might consider putting a governor on their car.

Also: not sure why it’s a crazy to analogise kiwis and Americans. I honestly thought it was common knowledge that folks with lots of speeding tickets tend to crash more frequently than population.

[1] https://pmc.ncbi.nlm.nih.gov/articles/PMC4851372/
by prash2488 | 2025-04-28 05:38:27+00:00
I am working on a PromptLibrary (https://promptlib.prashamhtrivedi.in/) to organise my prompts and make it accessible from multiple clients (Including chatbots (via chrome extensions), CLIs, IDE extensions amongst the few).

I wanted a library to store my own prompts once and retrieve it in multiple locations (i.e. Try something on claude desktop and then once I wrinkle out the edges, load it in Roo code or claude code and use it.) Give some variables to the prompt and creating infinite versions of same prompt by providing the value. Or having the versions of each prompt.

Currently I have the landing page, soon (In max 10 days) I will make it live for everyone to use.
by xvector | 2025-04-28 05:39:25+00:00
If life feels empty to you, I'm sorry to hear that. I hope it gets better soon. I feel the opposite - there is so much to do, and so little time. I am also happy and content just... existing.

I don't think a social problem (that will be solved in time, and is already solved in some countries) is a reason to prevent this from happening.

Social problems can be fixed, death is final. If euthanasia doesn't become legal before, it certainly will be after.
by robocat | 2025-04-28 05:40:15+00:00
Advancing paternal age was not associated with an increase in risk for either Down syndrome or chromosomal disorders other than Down syndrome. Multiple neonatal and pediatric disorders have been linked to older paternal ages. The risk of paternal age has been difficult to estimate and interpret because children often have parents whose ages are similar and likely to be confounded.

From "Disentangling the roles of maternal and paternal age on birth prevalence of Down syndrome and other chromosomal disorders using a Bayesian modeling approach" https://bmcmedresmethodol.biomedcentral.com/articles/10.1186...
by ViscountPenguin | 2025-04-28 05:41:14+00:00
Until very recently this was the case in Australia. If you started going to a different doctor you had to sign a form authorising record transfer.

This was somewhat annoying since unlike the UK system, the Australian system is essentially private GPs getting paid for your individual appointments by the government (so called bulk billing), so there's no guarantee that you can go to the same doctor every time.
by globnomulous | 2025-04-28 05:41:20+00:00
And then there's the further question of where we draw the line in ourselves. One of my teachers -- a philosopher -- once said that real, actual thought is incredibly rare. He's a world-renowned expert but says he can count on one hand the number of times in his life that he felt he was thinking rather than remembering and reorganizing what he already knew.

That's not to say "are you remembering or reasoning" means the same thing when applied to humans vs when it's applied to LLMs.
by fuzzfactor | 2025-04-28 05:42:43+00:00
Some people are just not too smart. How they got into leadership positions having responsibility for important things, dangerous materials, or even worse devices designed to kill, had nothing to do with brains. Scattered across the world in more places that would have never settled for that kind of thing in previous decades, although you do sometimes need to go back a good bit.

>Just damaging even a non-stealthy crewed U.S. military aircraft would be a major propaganda victory for the Yemeni militants.

Could be bittersweet if it's like poking a gorilla and leads to a scorched-earth policy eventually taking effect and escalating until Houthis have nothing left to fight for, or to fight anybody with. Regardless, their ability to disrupt shipping definitely needs to be completely neutralized at the soonest.

Plus if they fulfill their ambition to shoot down a B-2, how much of an idiot would you have to be?

Why would the bomber not be armed with a "little" nuclear ordnance "just in case"? This would then have to be detonated if it was on enemy territory if nothing else to keep it from falling into the wrong hands.

You can't be too careful with extremists.

Whether they are Americans or anti-Americans, I'm the first to admit that.

Some people are just not too smart.
by anshumankmr | 2025-04-28 05:43:17+00:00
This was something I have been noticing for a while. I had a conversation about some legal matters involving the estate of my grandfather who passed away recently, with 4o and it made a humourous reply (something along the lines of oh well your life wasn't bad enough already) along with the legal advice. The joke wasn't offensive, but a bit strange cause the matter is very serious. This was about a month ago.

full disclosure: I do use the app a little too much, the memory was clogged with a lot of personal stuff,major relationship troubles, knee injury,pet cat being sick frequently in January, and a lot of personal stuff.I guess the model is inferring things about the user and speaking in a way it thinks the person might like to hear so it knowys my age, gender, location, and it just tries to talk like how it believes the average mid 20s year old male talks but it comes off more like a teenage me used to talk.
by sjdrc | 2025-04-28 05:44:09+00:00
What are you talking about? There are massive breaches of huge companies who should be doing better all the time.

In 2017: > More than 40% of the population of America was potentially impacted by the Equifax data breach.

In 2022: > In September 2022, Optus experienced a major data breach that exposed the personal information of millions of customers

That's just 2 off the top of my head.
by tsimionescu | 2025-04-28 05:44:26+00:00
This goes in complete opposition to every single study ever performed on this matter. Higher speed very directly translates into higher risk of accidents and higher risk of fatalities or serious injuries per accident. Now, it's true that there are cases of occasional unscrupulous places placing onerous speed limits only to force fines (I've seen places on highways that are normally 100 km/h that have a short portion of 30km/h on flat straight land with no houses around, but with a good place for a police car to stay hidden), but these are the exception and nowhere near the rule.
by caseyy | 2025-04-28 05:44:28+00:00
I disagree. There is increasing conversation in the medical community[0] about living past one’s health-span for years.

While fear of death is widely considered universal, many people (for various reasons) fear death significantly less than others[1]. Fear of death levels appear to generally stabilize to low past 60 years of age. Many philosophies reject the fear of death, including some of our very popular religions. Only about half of terminally ill patients feel clinically significant death anxiety[2]. It is normal to not fear death without being depressed, enlightened, or stupid.

I think it’s not so black and white as evolutionary psychology might suggest.

[0] https://peterattiamd.com/outlive/

[1] https://en.wikipedia.org/wiki/Death_anxiety

[2] https://pubmed.ncbi.nlm.nih.gov/35609222/
by bitwize | 2025-04-28 05:45:23+00:00
"I was optimistic when my friend told me about his new hammer and how much it helped him assemble a cabinet he was working on.

Then I remember that this is the same technology that failed to drive in screws for a project I was working on a week ago."

The AI that's being used in applications like this is not generative AI. It really is just "sparkling statistics" and it's tremendously useful in applications like this because it can accelerate the finding of patterns in data that form the basis of new discoveries.
by rijavecb | 2025-04-28 05:45:49+00:00
I recently started working on a fishing journal/log kind of app. I got that idea last year when returning from fishing with dad, that it would be nice if we could track what we caught each time we went fishing, where we went, and to track some details (water and wea details). There apps that already do that, and one could also use Excel or just paper notebook, so I'm making this mainly for us and his friends to use. It's still early, but I'd like to add groups so you can exchange messages or catches with your friends, add stats allowing you to see for example at what time and where you caught most fish, or using which lure or bait. The app is in Serbian though, but here's a link if you want to check it out: https://buckaros.com
by xyst | 2025-04-28 05:47:54+00:00
EHRs (electronic health records) were suppose to be the "common charting protocol" back when ACA passed.

Unfortunately so many junk systems were pushed to the market and the "common charting protocol" is highly dependent on the EHR used by the hospital system.

There _was_ supposed to be some interoperability between EHRs but I honestly haven’t been following it for quite some time.

As for availability of medical history to researchers, I highly doubt this will happen.

Big tech has ruined the trust between people and technology. People gave up their data to G, MS, FB, and others for many years.

We have yet to see any benefit for the common man or woman. Only the data is used against us. Used to divide us (echo chambers). Used to manipulate us (buy THIS, hate that, anti WoKe). Used to control uneducated and vulnerable population. Used to manipulate elections. Used to enrich the billionaire class.
by ApolloFortyNine | 2025-04-28 05:48:27+00:00
Found another article that mentions it adjusts to the speed limit and allows you to go up to 9mph over.

Its hard to find issue with applying it only to the biggest offenders, but if this does break out into all cars in 10 years we'll have yet another example of slippery slope regulations. Passing safely (single lane roads) for one would likely be more dangerous in this reality.
by adrian_b | 2025-04-28 05:48:34+00:00
It is unlikely that it has better corrosion properties than a cheaper copper alloy, like copper-nickel alloy.

This new alloy is useful only for high-temperature applications, like turbines and heat exchangers, where its main advantage over the existing alloys (based on nickel or cobalt) is its much higher thermal conductivity.

Moreover, the kinds of stainless steel that have little or no nickel content (e.g. ferritic, martensitic, superferritic, duplex, manganese-austenitic) will always have a price several times lower than any copper alloy.

This copper alloy will be rather expensive due to the high cost of tantalum. However the content in tantalum is small, so the price will remain acceptable for its applications.
by MadMatt13 | 2025-04-28 05:48:39+00:00
I've been following the dev of Talanoa and used it as an early beta tester for almost a month now.

Although it's not perfect yet, I am really enjoying getting used to this way of handling my emails and turning them to tasks. I also like the way new emails are organized and popping up, feeling less polluted by the mass of "daily notifications spam".

I'm looking forward to use this with my non gmail accounts and be able to setup multiple accounts.

When I see the improvements from a month ago to now, it gives me high hopes for the future of this.

Good luck!

PS: kudos on your non-AI disclaimer. We need more apps that just work these days.
by r9zgWUN7WS3k6i | 2025-04-28 05:48:41+00:00
It seems that you're thinking about the SWF content in terms of playback, which is not what they were doing. They were looking inside the bundles for ZIP files and malware (4chan users to shove horrible things into the files they upload), and extracting metadata from the SWF. We'll never know the exact details unless they share the source code. It is possible to write a secure SWF parser, but I think they decided to stop supporting this relic instead.

> Ruffle

Yes, they used that. Take a look at the board.
by hyperbrainer | 2025-04-28 05:48:47+00:00
If you wish to approach Category Theory from the viewpoint of a programmer, not a mathematician, I suggest Bartosz Milewski's book Category Theory for Programmers. For this, all you need is some previous programming experience. He uses C++ and Haskell iirc but as long as you can read snippets of code, you'll be fine.

I am suggesting this since you said you want to better understand functional programming. Category Theory, as mathematicians look at it, is an extremely abstract field. If you want to do pure math related stuff in Category Theory, and only then, I would say important prereqs are Abstract Algebra and Topology. I believe the motivation for Category theory lies in Algebraic Geometry and Algebraic Topology, but you definitely don't need to be an expert on these to learn it.
by ViscountPenguin | 2025-04-28 05:49:11+00:00
I'm not too confident that mortality will be cured this century. Even if we cure some of the big targets (dementia, muscle wasting and cancer come to mind) there will inevitably be a long tail of problems.

If it were just that, I might still be hopeful, but the latency on aging cure experiments is inevitably going to be quite long, and that won't change without massive advances in biological simulations.