Miracle-dz/UniFAR-FTUs huggingface dataset:
BPS Wall Crossing and Topological Strings

By embedding N=2 gauge theories in string theory and utilizing string dualities we map the counting of BPS states with arbitrary electric and magnetic charges to computations of an A-model topological string on an associated geometry constructed from the data of the SW curve. We show how the conjecture of Kontsevich and Soibelman regarding wall crossing, as well as a more refined version which captures the spin content of BPS states, is a natural consequence. Chern-Simons theory realized on A-branes and a twistorial construction play key roles.
Maximum GCD Among Pairs of Random Integers

Abstract Fix α > 0, and sample N integers uniformly at random from {1, 2, . , ⌊eαN ⌋}. Given η > 0, the probability that the maximum of the pairwise GCDs lies between N 2–η and N 2+η converges to 1 as N → ∞. More precise estimates are obtained. This is a Birthday Problem: two of the random integers are likely to share some prime factor of order N 2/log(N). The proof generalizes to any arithmetical semigroup where a suitable form of the prime number theorem is valid.
Elucidating genomic patterns and recombination events in plant cybrid mitochondria

Key message Cybrid plant mitochondria undergo homologous recombination, mainly BIR, keep a single allele for each gene, and maintain exclusive sequences of each parent and a single copy of the homologous regions. Abstract The maintenance of a dynamic equilibrium between the mitochondrial and nuclear genomes requires continu-ous communication and a high level of compatibility between them, so that alterations in one genetic compartment need adjustments in the other. The co-evolution of nuclear and mitochondrial genomes has been poorly studied, even though the consequences and effects of this interaction are highly relevant for human health, as well as for crop improvement programs and for genetic engineering. The mitochondria of plants represent an excellent system to understand the mechanisms of genomic rearrangements, chimeric gene formation, incompatibility between nucleus and cytoplasm, and horizontal gene transfer. We carried out detailed analyses of the mtDNA of a repeated cybrid between the solanaceae Nicotiana tabacum and Hyoscyamus niger . The mtDNA of the cybrid was intermediate between the size of the parental mtDNAs and the sum of them. Noticeably, most of the homologous sequences inherited from both parents were lost. In contrast, the majority of the sequences exclusive of a single parent were maintained. The mitochondrial gene content included a majority of N. tabacum derived genes, but also chimeric, two-parent derived, and H. niger -derived genes in a tobacco nuclear background. Any of these alterations in the gene content could be the cause of CMS in the cybrid. The parental mtDNAs interacted through 28 homologous recombination events and a single case of illegitimate recombination. Three main homologous recombination mechanisms were recognized in the cybrid mitochondria. Break induced replication (BIR) pathway was the most frequent. We propose that BIR could be one of the mechanisms responsible for the loss of the majority of the repeated regions derived from H. niger .
CHANGES IN CANADIAN FAMILY INCOME AND FAMILY CONSUMPTION INEQUALITY BETWEEN 1978 AND 1992

This paper uses Canadian cross-sectional income and expenditure data to examine changes in the distribution of family income and family consumption during the period 1978 to 1992. Family consumption data are analyzed because in the presence of intertemporal consumption smoothing, the cross-sectional distribution of consumption may characterize the distribution of lifetime wealth. I find that both Canadian family income inequality and Canadian family consumption inequality moved countercyclically. In addition, both Canadian family income inequality and Canadian family consumption inequality trended upward over the period; however, the change in family consumption inequality was much smaller than the change in family income inequality, suggesting that inequality in the distribution of lifetime wealth may have changed much less than is suggested by changes in the distribution of income.
Complex regulation of store-operated Ca 2 (cid:1) entry pathway by PKC- ε in vascular SMCs

Complex regulation of store-operated Ca 2 entry pathway by PKC- ε in vascular SMCs. Am role of PKC in the regulation of store-operated Ca 2 (cid:1) entry (SOCE) is rather controver-sial. Here, we used Ca 2 (cid:1) -imaging, biochemical, pharmacological, and molecular techniques to test if Ca 2 (cid:1) -independent PLA 2 (cid:2) (iPLA 2 (cid:2) ), one of the transducers of the signal from depleted stores to plasma membrane channels, may be a target for the complex regulation of SOCE by PKC and diacylglycerol (DAG) in rabbit aortic smooth muscle cells (SMCs). We found that the inhibition of PKC with chelerythrine resulted in signiﬁcant inhibition of thapsigargin (TG)-induced SOCE in proliferating SMCs. Activation of PKC by the diacylglycerol analog 1-oleoyl-2-acetyl- sn -glycerol (OAG) caused a signiﬁcant depletion of intracellular Ca 2 (cid:1) stores and triggered Ca 2 (cid:1) inﬂux that was similar to TG-induced SOCE. OAG and TG both produced a PKC-dependent activation of iPLA 2 (cid:2) and Ca 2 (cid:1) entry that were absent in SMCs in which iPLA 2 (cid:2) was inhibited by a speciﬁc chiral enantiomer of bromoenol lactone ( S -BEL). Moreover, we found that PKC regulates TG- and OAG-induced Ca 2 (cid:1) entry only in proliferating SMCs, which correlates with the expression of the speciﬁc PKC- ε isoform. Molecular downregulation of PKC- ε impaired TG-and OAG-induced Ca 2 (cid:1) inﬂux in proliferating SMCs but had no effect in conﬂuent SMCs. Our results demonstrate that DAG (or OAG) can affect SOCE via multiple mechanisms, which may involve the depletion of Ca 2 (cid:1) stores as well as direct PKC- ε -dependent activation of iPLA 2 (cid:2) , resulting in a complex regulation of SOCE in proliferating and conﬂuent SMCs. conﬂuence) and 95% conﬂuent SMCs were transfected with antisense and scrambled oligonucleotides [the same as successfully used in a previous study (36)] directed against PKC- ε : antisense oligonucleotide 5 (cid:8) -CATGAGGGC-CGATGTGACCT-3 (cid:8) and scrambled oligonucleotide 5 (cid:8) -TACGCATA-ACGCGCTGGTGG-3 (cid:8) . Experiments were conducted 60–72 h after transfection. The oligonucleotides were labeled with ﬂuorescein, and its presence in the cells was veriﬁed by imaging (excitation at 480 nm and emission at 515 nm) before the experiments.
Primena programskog paketa MATLAB za optimizaciju parametara obrade glodanjem

Optimally chosen parameters of the processing mode directly influence total costs of production of a single product and therefore the profit of the company as well. In this paper, the choice of optimum parameters of the milling processing mode by using the method of particle swarm optimization (PSO) is shown. The goal of optimization is represented through the goal function (optimization function or optimization criterion) and by using the method of optimization PSO, minimum costs of machining process are obtained. Optimization function is also represented graphically for the purpose of clearer analysis on the technological area in which the values of machining mode that give minimum costs of machining process are presented.
PT-Invariance and Indefinite Metric

A new proof is given for why the non-Hermitian, PT-Invariant cubic oscillator with imaginary coupling has real eigenvalues. The proof consists of two steps. In the first step, it is shown that for many PT-Invariant Hamiltonians, one can define corresponding Hermitian Hamiltonians that have the same eigenvalues when quantized using indefinite metric. The second step is to show that the indefinite-metric eigenvalues of the Hermitian cubic oscillator are real since the norms of its eigenstates do not vanish. The correspondence between PT-Invariant Hamiltonians and indefinite-metric Hermitian Hamiltonians is further discussed as a way to determine vacuum stability for certain supersymmetric gauge theories.
High prevalence of Schistosoma mansoni infection among adults with chronic non - communicable diseases in Malawi - a cross sectional study at Mangochi District Hospital

Background Schistosomiasis is a parasitic infectious disease caused by flatworms of the Schistosoma genus. The global burden of schistosomiasis is high. In Malawi, schistosomiasis is among the top 20 causes of outpatient department visits in health facilities. Schistosomiasis is among the most important but neglected causes of non-communicable diseases (NCD) peculiar to tropical endemic settings. While much is known about the contribution of S. haematobium to the NCD burden in Malawi, the role of S. mansoni remains largely unknown. Methods We conducted a cross-sectional study at Mangochi District Hospital. Adults over 18 years diagnosed with NCDs (n = 414), admitted or attending weekly outpatient clinics were recruited between August 2021 and February 2022. Data were collected on sociodemographic characteristics, medical history, body weight, blood pressure, and fasting blood glucose. Stool and midstream urine were collected for Kato Katz (KK) microscopy and urine circulating cathodic antigen (CCA) tests respectively. We computed prevalence of S. mansoni as number of positive KK and CCA tests, each divided by total submitted samples. Univariate and multivariable logistic regression were done to evaluate risk factors of NCDs and association between S. mansoni infection and NCDs. Results We recruited 414 participants, mean age 57 years (SD 16), 67% of whom were female. Prevalence of S.mansoni based on urine CCA was 15% (95% CI 11 - 19) and 0% on KK microscopy. Hypertension was the most common condition with a prevalence of 85% (95% CI 81 - 89), followed by diabetes mellitus with a prevalence of 42% (95% CI 37 - 46) and heart disease with a prevalence of 3% (95% CI 2 - 5). S. mansoni infection was not significantly associated with hypertension (OR 1.2 (95% CI 0.5 -3.1), p - value 0.47), diabetes (OR 0.6 (95% CI 0.3- 1.1), p - value 0.117) or heart disease (OR 2.0 (95% CI 0.4 - 10), p - value 0.416). Conclusions We observed high prevalence of S. mansoni infection among adults in the study. This is within the range observed in children in Mangochi from 10 - 56.7%.
Measuring circadian rhythms in patients with dementia: protocol for a scoping review

Introduction Most physiological processes are under circadian regulation. Disturbances to circadian rhythms are common and often early symptoms in dementia. There is a gap in the literature regarding how and which circadian functions have been, or could optimally be, measured in patients with dementia. This protocol outlines a scoping review to identify which and how circadian variables have been studied in patients with dementia and mild cognitive impairment, and examine whether feasibility, acceptability, appropriateness, and utility in clinical practice has been considered. Methods and analysis The scoping review will be conducted in accordance with the Joanna Briggs Institute methodology for scoping reviews and will be reported in line with the Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR). We will systematically search five electronic bibliographic databases (MEDLINE, CINAHL, EMBASE, The Cochrane Central Register of Controlled Trials (CENTRAL), PsycInfo). There will be no restriction on date of publication or language; corresponding authors will be contacted where relevant non-English articles are identified to request a translation. Search results will be merged using reference management software and duplicates will be removed. To ensure consistency in applying eligibility criteria, 10% of retrieved articles will be checked by each reviewer in the team at the title and abstract screening stage and full texts will be reviewed by at least 2 reviewers. Data from eligible articles will be extracted using a standardised form. Where study outcomes (e.g., patient and public involvement, adherence) have not been described in the article, authors will be contacted in case relevant data is available to share but was omitted from the main report. Results will be presented as a narrative synthesis as study and population heterogeneity will likely prohibit meta-analysis. Ethics and dissemination Ethical approval is not required as the scoping review methodology does not involve human or animal participants. This review will provide an extensive overview of established and emerging trends in measurement of circadian rhythms in dementia and identify gaps in the research to inform future clinical and research practice. The review will also highlight whether patient and public involvement, participant burden, and clinical usefulness of methods have been considered in developing protocols. Results will be disseminated in a peer-reviewed publication.
An Insulin-like Growth Factor-mediated, Phosphatidylinositol 3* Kinase-independent Survival Signaling Pathway in b Tumor Cells

Hyperproliferation of tumor cells usually coincides with increased tumor cell apoptosis. To overcome apoptosis, tumor cells frequently induce the expression of growth factors that mediate cell survival. In nontransformed cells, including fibroblasts and neurons, survival factor-mediated signal transduction involves the activation of phosphatidylinositol 3*kinase (PI-3K) and protein kinase B/c-Akt (PKB). Here we demonstrate that tumor cell lines derived from a transgenic mouse model of pancreaticb cell carcinogenesis use insulin-like growth factors to repress apoptosis independently of PI-3K and PKB. The results indicate that tumor cells can use additional survival signal transduction pathways.
Principles of genome folding into topologically associating domains

This review discusses the features of TADs across species, and their role in chromosome organization, genome function, and evolution. Understanding the mechanisms that underlie chromosome folding within cell nuclei is essential to determine the relationship between genome structure and function. The recent application of “chromosome conformation capture” techniques has revealed that the genome of many species is organized into domains of preferential internal chromatin interactions called “topologically associating domains” (TADs). This chromosome compartmentalization has emerged as a key feature of higher-order genome organization and function through evolution. Although TADs have now been described in a wide range of organisms, they appear to have specific characteristics in terms of size, structure, and proteins involved in their formation. Here, we depict the main features of these domains across species and discuss the relation between chromatin structure, genome activity, and epigenome, highlighting mechanistic principles of TAD formation. We also consider the potential influence of TADs in genome evolution.
Harnack inequality for SDE with multiplicative noise and extension to Neumann semigroup on nonconvex manifolds

By constructing a coupling with unbounded time-dependent drift, dimension-free Harnack inequalities are established for a large class of stochastic differential equations with multiplicative noise. These inequalities are applied to the study of heat kernel upper bound and contractivity properties of the semigroup. The main results are also extended to reflecting diffusion processes on Riemannian manifolds with nonconvex boundary.
Uncertain portfolio selection with mental accounts and background risk

In real life, investors face background risk which may affect their portfolio selection decision. In addition, since the security market is too complex, there are situations where the future security returns cannot be reflected by historical data and have to be given by experts' estimations according to their knowledge and judgement. This paper discusses a portfolio selection problem with background risk in such an uncertain environment. In the paper, in order to reflect different attitudes towards risk that vary by goal in one portfolio investment, we apply mental accounts to the investment. Using uncertainty theory, we propose an uncertain portfolio selection model with mental accounts and background risk and provide the determinate form of the model. Moreover, we discuss the shape and location of efficient frontier of the subportfolios with background risk and without background risk. Further, we present the conditions under which the optimal aggregate portfolio is on the efficient frontier when return rates of security and background asset are all normal uncertain variables. Finally, a real portfolio selection example is given as an illustration.
A Multi Criteria Decision Making Based Novel Model For Supplier Selection

Received/Geliş: 20.11. 2019 Accepted/Kabul: 06.02. 2020 Abstract: Supplier selection and measurement of supplier performance are multi-criteria decision making (MCDM) problems and have strategic importance for all industries. The study contains analyzed factors that are affecting the process of the supply chain concerning supplier performance. Supplier performance measures is a tool to determine whether suppliers are doing their job as expected. The importance of supplier performance measurement should not be underestimated due to direct and indirect productivity-related consequences. Supplier evaluation is a complex multiple criteria decision-making problem that is affected by several conflicting factors. Therefore, the measurement of supplier performance has been becoming crucial and critical throughout the world. The purpose of this paper is to investigate the MCDM methods and propose a novel method to check how the performance of suppliers is being measured using three different methods. Qualification and final selection of the supplier can be done with a proposed novel model. In the study, the criteria are weighted with the Analytical Hierarchy Process, while TOPSIS and VIKOR methods are used to evaluate and rank the suppliers. Evaluating supplier performance, derive the importance of the main criteria and sub-criteria applied in decision-matrix to sort the suppliers according to the measurement of supplier performance criteria.
A category of quantum categories

Quantum categories were introduced in [4] as generalizations of both bi(co)algebroids and small categories. We clarify details of that work. In particular, we show explicitly how the monadic definition of a quantum category unpacks to a set of axioms close to the definitions of a bialgebroid in the Hopf algebraic literature. We define notions of functor and natural transformation for quantum categories.
Localization techniques in circle-equivariant KK-theory

Let T be the circle and A be a T-C*-algebra. Then the T-equivariant K-theory of A is a module over the representation ring of the circle. The latter is a Laurent polynomial ring. Using the support of the module as an invariant, and techniques of Atiyah, Bott and Segal, we deduce that there are examples of T-C*-algebras A not KK^T-equivalent to any commutative T-C*-algebra. This is in contrast to the non-equivariant situation, in which any C*-algebra in the boostrap category is KK-equivalent to a commutative one. Our examples arise from dynamics, and include Cuntz-Krieger algebras with their usual circle actions. Using similar techniques, we also prove an equivariant version of the Lefschetz fixed-point formula. This is a special case of a result with Ralf Meyer that applies to general compact connected groups. The Lefschetz theorem equates the module trace of the module map of the T-equivariant K-theory of a smooth compact manifold induced by an equivariant self-correspondence of the manifold, with an appropriate Kasparov product; the Kasparov product is the T-equivariant index of the Dirac operator on a suitable `coincidence manifold' of the correspondence. Finally, we prove several results related to localization and the Kunneth and universal coefficient theorems, and give an essentially complete description of the T-equivariant K-theory of compact spaces, by combining localization techniques of Atiyah and Segal and results of Paul Baum and Alain Connes for equivariant K-theory of finite group actions.
Geometry of the quantum projective plane

We review some of the geometry of the quantum projective plane with emphasis on the construction of a differential calculus and of the Dirac operator (of a spin^c-structure). We also report on anti-self-dual connections on line bundles, the spectrum of associated (gauged) Laplacian operators, and on classical and quantum characteristic classes.
EFFECTS OF KAYAKING ON MOTOR SKILLS IN CHILDREN AND ADOLESCENTS WITH DOWN SYNDROME

Rev Bras Med Esporte – Vol. 26, No 4 – Jul/Ago, 2020 ABSTRACT Introdução: A síndrome de Down (SD) é uma afecção genética que se caracteriza por distribuição numérica inadequada no pareamento cromossômico, com material genético extra relacionado com o par 21 que leva a alterações que afetam o desenvolvimento de diversos componentes motores. Objetivos: Analisar os efeitos do treinamento de canoagem durante oito semanas sobre as habilidades motoras grossas em crianças e adolescentes com SD. Métodos: Sete indivíduos com SD (10,8 ± 2 anos), quatro do sexo masculino e três do sexo feminino participaram do estudo. Para avaliar as habilidades motoras grossas, empregou-se a bateria de Teste de Coordenação Corporal para Crianças (Körperkoordination Test für Kinder, KTK). O teste de Wilcoxon foi usado para comparar os valores de habilidades motoras grossas antes e depois do KTK e o teste de Mann-Whitney foi usado para comparar os indivíduos por sexo. O tamanho do efeito foi calculado pela escala de Cohen (1977) e nível de significância de p < 0,05 foi adotado. Resultados: Os indivíduos apresentaram resultados estatisticamente significativos em todas as tarefas do teste de coordenação motora grossa e o efeito produzido pela intervenção foi moderado. Conclusão: Conclui-se que oito semanas de treinamento de canoagem são suficientes para produzir desenvolvimento das habilidades motoras grossas de crianças e adolescentes com Síndrome de Down. Nível de Evidência IV; Série de casos.
Assessing vulnerabili es in transport networks: a graph-theore c approach

Recebido: 30 de novembro de 2019 Aceito para publicação: 28 de setembro de 2020 Publicado: 30 de abril de 2021 Editor de área: Bruno Vieira Bertoncini ABSTRACT The design and maintenance of sustainable and resilient transport systems depend on the iden0fica0on of possible vulnerabili0es before crises occur so that infrastructure and strategies of ac0on are effec0vely developed for 0mes of crisis. However, given the complexity of transport systems, the proposed methods for assessing vulnerabili0es are difficult to implement and require data inaccessible to most Brazilian municipali0es. Given this scenario, and intending to simplify the preliminary analysis of a system in the search for vulnerabili0es, the objec0ve of this paper is to present the centrality measure from graph theory that best represents the local vulnerability of inland transport networks in Brazilian ci0es. The method proposed in the study was the systema0c degrada0on of the network measuring the decay in con0nuity on the system, defined as the propor0on of valid paths that remain in the network a;er the removal of a certain number of roads. The results pointed out the betweenness centrality is the metric that best reflects vulnerability since the a=ack strategy that progressively removes the roads with greater betweenness centrality presents a faster decay of con0nuity. With this result, we expect to facilitate the detec0on of vulnerabili0es in transport systems and to guide the crea0on of more resilient transport systems.