Miracle-dz/UniFAR-FTUs huggingface dataset:
Phenotypic and Molecular Detection of IMP and SPM Metallo-Beta-Lactamases in Clinical Isolates of Carbapenem Resistant Pseudomonas aeruginosa

Objectives: Metallo-beta-lactamases play a major role in the resistance of Pseudomonas aeruginosa to carbapenems. The aim of this study was the phenotypic and molecular detection of IMP and SPM carbapenemase genes in 100 carbapenem-resistant clinical isolates of P. aeruginosa. The isolates identified using standard microbiological tests, and their antibiotic susceptibility pattern determined by disk agar diffusion (Kirby Bauer) method. Phenotypic identification of Metallo-beta-lactamase-producing strains assessed by the combined disk test (CDT). Then, PCR was used to detect the presence of IMP and SPM genes.Results: The highest and lowest levels of antibiotic resistance were observed against gentamicin (40%) and piperacillin-tazobactam (13%), respectively. Besides, 40 isolates (40%) had the Multi-drug Resistant (MDR) phenotype, while 5 (12.5%) MDR isolates were resistant to all antibiotics tested. The results of the CDT showed that among 43 carbapenem non-susceptible clinical isolates of P. aeruginosa, 33 (76.74%) isolates were Metallo-beta-lactamase-producing strains. Also, the frequency of the IMP gene was determined to be 9%, while none of these isolates carried the SPM gene. Due to the high prevalence of carbapenem-resistant and MDR P. aeruginosa in this study, routine antibiotic susceptibility testing and phenotypic identification of carbapenemase production by this bacterium are necessary for proper selection of antibiotics.
Evaluation of an English Course at an Anatolian High School with an Eclectic Point of View: A Case Study.

The purpose of this study was mainly to explore how theories of learning applied at English classes at Anatolian High Schools. It has been prepared through the findings of a 9th class English course implemented at an Anatolia High School under the control of Ministry of National Education and it involves four parts: Firstly, some brief explanation about eclectic approach to teaching and the major theories are given and it is followed by the findings of the interviews, observation and analysis of the course. The participants consisted of three English language teachers and 9th class students at an Anatolian High School, Ankara, Turkey. In the spring semester of 2005-2006, the researcher carried out interviews and additionally made a five-hour-visit to one of the classes to determine students’ attitudes towards the lesson and to observe how the teacher applies the teaching methodologies her classroom.
Normas

The high prevalence of inflammatory rheumatic diseases in women of childbearing age increases the risk of exposure to antirheumatic agents during conception, pregnancy and breast feeding. The decision for pharmacological treatment initiation/maintenance should be the result between the severity of maternal disease and the risk/benefits with treatment. The aim of this paper was to review recent literature about drug fetal safety profile, strength the importance of monitoring the pregnancy in pa-
A Fiber-Optic Tether for the Hull Search UUV System Documentation

Abstract : This document describes the installation and operation of a fiber-optic (FO) tether system developed to augment unmanned underwater vehicles (UUVs) conducting ship hull inspection missions, defines the required specifications that will allow the integration and installation of a FO tether system on UUVs with ship hull inspection capability, provides the parts list and vendors list for this system, details the sequence required to assemble the UUV telemetry subassembly from parts described in the parts list, captures outcomes and design decisions based on trade studies, engineering analysis, and fleet user inputs that affect the final configuration of the FO tether system for the hull search UUV, and provides assembly drawings for the system.
A design approach and selected wind tunnel results at high subsonic speeds for wing-tip mounted winglets

Winglets, which are small, nearly vertical, winglike surfaces, substantially reduce drag coefficients at lifting conditions. The primary winglet surfaces are rearward above the wing tips; secondary surfaces are forward below the wing tips. This report presents a discussion of the considerations involved in the design of the winglets; measured effects of these surfaces on the aerodynamic forces, moments, and loads for a representative first generation, narrow body jet transport wing; and a comparison of these effects with those for a wing tip extension which results in approximately the same increase in bending moment at the wing-fuselage juncture as did the addition of the winglets.
Peran Modal Sosial Terhadap Eksistensi Pasar Tradisional (Studi Kasus di Pasar Besar Malang)

Pasar tradisional sudah menjadi kebutuhan masyarakat indonesia, akan tetapi akhir-akhir ini kehadiran pasar modern mengancam eksistensi dari pasar tradisional ke depannya. Pada kenyataannya di Pasar Besar Malang pasar tradisional bisa bertahan berdampingan dengan ritel modern. Tujuan dari penelitian ini adalah untuk mengetahui peran modal sosial terhadap eksistensi pasar tradisional. Penelitian ini menggunakan pendekatan kualitatif dengan metode studi kasus. Hasil dari penelitian ini, yaitu Modal sosial yang terbentuk pada Pasar Besar Malang telah ada dan menjadi pendorong bagi pasar itu sendiri untuk bertahan, hal ini tercermin pada hubungan antarpedagang yang telah ada dan terpelihara dengan baik serta hubungan pedagang dengan pelanggan atau pembeli yang juga merupakan bentuk modal sosial, hubungan-hubungan ini menyangkut kepercayaan, jaringan serta nilai dan norma. Kata kunci: Pasar Tradisional, Eksistensi, Modal Sosial
Quantum Chemical Calculations on Locked Nucleic Acid based Antisense Modifications: A Density Functional Theory (DFT) Study at Monomer Level

Antisense technology has been developed as the next generation drug discovery methodology by which unwanted gene expression can be inhibited by targeting mRNA specifically with antisense oligonucleotides. It has been observed that a good number of these molecules entered into clinical trials at a faster rate and some of them got approved. The computational studies of antisense modifications based on phosphorothioate (PS), methoxyethyl (MOE), locked nucleic acids (LNA) may help to design better novel modifications. In the present study, newer LNA based modifications have been proposed. The conformational search and density functional theory (DFT) calculations have been used to investigate the quantum chemical parameters of PS, LNA, MOE, and novel LNA based proposed modifications. The conformational search has been done to identify the most and alternative stable conformations. The geometry optimization followed by single point energy calculation has been done at B3LYP/6-31G(d,p) level for gas phase and B3LYP/6-311G(d,p) level for the solvent phase of all modifications. The electronic properties and the quantum chemical descriptors for the frontier molecular orbitals of all the antisense modifications were derived and compared. The local and global reactivity descriptors, such as hardness, chemical potential, electronegativity, electrophilicity index, Fukui function calculated at DFT level for the optimized geometries. These are used for understanding the reactive nature and reactive sites of the modifications. A comparison of global reactivity descriptors confirmed that LNA based modifications are the most reactive modifications and prone to the chemical reactions. It may form stable duplex when it is bound to complementary nucleotides, compared to other modifications. Therefore, we are proposing that one of our proposed antisense modification (A3) may show strong binding to the complementary nucleotide as LNA and may also show reduced toxic effects like MOE.
Coordinated Multi-Point in Mobile Communications: From Theory to Practice

A self-contained guide to coordinated multi-point (CoMP), this comprehensive book covers everything from theoretical basics to practical implementation. Addressing a wide range of topics, it highlights the potential gains of CoMP, the fundamental degrees of freedom involved and the key challenges of using CoMP in practice. The editors and contributors bring unique real-world experience from running the world's first and largest test beds for LTE-Advanced, and recent field trial results from these tests are presented. With detailed insight into the realistic potential of CoMP as a key technology for LTE-Advanced and beyond, this is a must-read resource for professionals and students who want the big picture on CoMP or require in-depth knowledge of how to build cellular communication systems for the future.
Human Resources in Multilevel Service Provision Performance: The Role of Field Offices and Local Organizations

The public management literature has extensively explored human resources’ (HR) contribution to organizational performance. However, HR approaches are seldom explored when assessing multilevel service provision. This research studies the HR-performance relationship when organizations at different government levels contribute to service provision. Beyond directly engaged local organizations, HR in national organizations’ field offices providing ancillary services may influence local service performance; however, local organizations’ HR levels moderate this contribution. Education in Colombia allows testing this model. While local schools directly provide classroom instruction, a national agency’s (Instituto Colombiano de Bienestar Familiar, ICBF) field offices provide related services. Relative workforce size and educational attainment serve to assess HR of schools and ICBF’s field offices while high school enrollment and dropout rates capture education provision performance. Schools’ HR increase performance and moderate ICBF’s indirect influence, offering evidence for both substitutive and reinforcing relationships between local and national organizations in service provision.
Compact Antennas and Arrays for Unmanned Air Systems

Compact Antennas and Arrays for Unmanned Air Systems James A. Eck Department of Electrical Engineering, BYU Master of Science A simple and novel dual-CP printed antenna is modelled and measured. The patch antenna is small and achieves a low axial ratio without quadrature feeding. The measured pattern shows axial ratio pattern squinting over frequency. Possible methods of improving the individual element are discussed, as well as an array technique for improving the axial ratio bandwidth. Three endfire printed antenna structures are designed, analyzed, and compared. The comparison includes an analysis of costs of production for the antenna structures in addition to their performance parameters. This analysis concludes that cost of materials primarily reduces the size of antennas for a given gain and bandwidth. An antenna stucture with an annular beam pattern for down-looking navigational radar is proposed. The antenna uses sub-wavelength grating techniques from optics to achieve a highly directive planar reflector which is used as a ground plane for a monopole. A fan-beam array element is fabricated for use in a digitally steered receive array for obstacle avoidance radar. The steered beam pattern is observed. The element-dependent phase shifts for a homodyned signal in particular are explored as to their impact on beam steering.
IVY: The Immersive Visual environment at York

Given the limitations of head mounted display systems, there has been significant interest in the development of large-scale virtual environments such as video walls, immersive project displays, and similar devices. Although these devices do provide a wide-field visual display, very few of these devices are completely immersive as the user may view the visual world or they may be tethered to the real world via tracking systems. In this paper we present the motivation and design of IVY: The Immersive Visual environment currently under construction at York University (IVY).
Milk Production and Milk Fat Components of Ettawah Grade Goatsunder Cool Wind Exposure

The research aimed to study the effect of cool wind exposure on feed intake, milk production, and milk fat components of Ettawah Grade goats. It was done using eight Ettawah Grade lactating goats of 1.5–2 years old, and weighed at 34.41.76 kg. These goats were in the third month of lactation with average milk production of 262.7+19.82 g/day. Feed given consisted of Napier grass (Pennisetum purpureum), Glyricidae and concentrates (mixed of wheat bran and rice bran). Concentrate feeding was given twice a day at 07.00 and 15.00, while Napier grass and Glyricidae was given ad libitum two hours after concentrate. This research followed Cross-over Design with 2 periods and 2 treatments, i.e. first non cool wind exposure (PEnor) and second, cool wind exposure (PEjuk). Results of the research showed that dry matter intake between PEnor and PEjuk were similar (P>0.05), being 1116 and 1117 g/day, respectively. The similar results were observed for intake of protein, fat, fiber as well as NFE. These similar intakes were pointed to the small difference in ambient temperature (only 1 oC) between PEnor and PEjuk. That conditions lead to the no difference between PEnor and PEjuk in milk production (195 vs 189 g/d) and milk fat components, such as millk fat (6.51 vs 6.64%), cholesterol (11.72 vs 11.85%), mono-unsaturated fatty acids (MUFA) (31.32 vs 31.90%) and the range of poly-unsaturated fatty acids (PUFA) (0.07-2.92 vs 0.05-2.59%). The conclusion that could be drawn from this research was mild cold exposure failed to improve feed intake and milk production due to small different of ambient temperature. Keywords : cool exposure, milk production, milk composition, Ettawah grade goat
An Application of UAV Attitude Estimation Using a Low-Cost Inertial Navigation System

Unmanned Aerial Vehicles (UAV) are playing an increasing role in aviation. Various methods exist for the computation of UAV attitude based on low cost microelectromechanical systems (MEMS) and Global Positioning System (GPS) receivers. There has been a recent increase in UAV autonomy as sensors are becoming more compact and onboard processing power has increased significantly. Correct UAV attitude estimation will play a critical role in navigation and separation assurance as UAVs share airspace with civil air traffic. This paper describes attitude estimation derived by post-processing data from a small low cost Inertial Navigation System (INS) recorded during the flight of a subscale commercial off the shelf (COTS) UAV. Two discrete time attitude estimation schemes are presented here in detail. The first is an adaptation of the Kalman Filter to accommodate nonlinear systems, the Extended Kalman Filter (EKF). The EKF returns quaternion estimates of the UAV attitude based on MEMS gyro, magnetometer, accelerometer, and pitot tube inputs. The second scheme is the complementary filter which is a simpler algorithm that splits the sensor frequency spectrum based on noise characteristics. The necessity to correct both filters for gravity measurement errors during turning maneuvers is demonstrated. It is shown that the proposed algorithms may be used to estimate UAV attitude. The effects of vibration on sensor measurements are discussed. Heuristic tuning comments pertaining to sensor filtering and gain selection to achieve acceptable performance during flight are given. Comparisons of attitude estimation performance are made between the EKF and the complementary filter.
Alternative Lengthening of Telomeres: Lessons to Be Learned from Telomeric DNA Double-Strand Break Repair

The study of the molecular pathways underlying cancer has given us important insights into how breaks in our DNA are repaired and the dire consequences that can occur when these processes are perturbed. Extensive research over the past 20 years has shown that the key molecular event underpinning a subset of cancers involves the deregulated repair of DNA double-strand breaks (DSBs) at telomeres, which in turn leads to telomere lengthening and the potential for replicative immortality. Here we discuss, in-depth, recent major breakthroughs in our understanding of the mechanisms underpinning this pathway known as the alternative lengthening of telomeres (ALT). We explore how this gives us important insights into how DSB repair at telomeres is regulated, with relevance to the cell-cycle-dependent regulation of repair, repair of stalled replication forks and the spatial regulation of DSB repair.
Fault Diagnosis of Gas Turbine Engines by Using MultipleModel Approach

The field of fault detection and isolation (FDI) has attracted much attention in control theory during the last three decades which has resulted in development of sophisticated FDI algorithms. However, increasing the complexity of FDI algorithms is not necessarily feasible. Particularly for on-line FDI, the FDI unit must have the minimum possible computation cost to prevent any long delays in fault detection. In this research, we try to address the FDI problem of a single spool jet engine by using a modified linear multiple model (MM). We first develop a novel symbolic computation-based method for linearization purposes such that the obtained linear models are subjected to the symbolic fault variables. By substituting certain values for these symbolic variables, one can obtain different linear models, which describe mathematically the healthy and faulty models. In order to select the operating point, we use this fact that for a given constant fuel flow (W_f), the system reaches a steady state, that is varying for different values of W_f. Therefore, the operating points for linearization can be determined by the level of the Power Level Angel (PLA) (different values of W_f). These operating points are selected such that an observer, which is designed as a candidate for the healthy mode, can accurately estimates the states of the system in healthy scenario and the number of false alarm then would be kept to minimum. If the system works at different operating points one can then discretize the W_f into different intervals such that in each interval a linear model represents the behavior of the original system. By using the obtained models for different operating points, one designs the corresponding FDI units. Second, we provide a modified multiple model (MM) approach to investigate the FDI problem of a single spool jet engine. The main advantage of this method lies in the fact that the proposed MM consists of a certain set of linear Kalman filter banks rather than using nonlinear Kalman filters such as the Extended Kalman Filter which requires more computational cost. Moreover, a hierarchical structural multiple model is used to detect and isolate multiple faults. The simulation results show the capability of the proposed method when it is applied to a single spool jet engine model.
Robotics: modular robots

Modular reconfigurable robots-experimental systems made by interconnecting multiple, simple, similar units-can perform shape shifting. A robot made up of a chain of simple hinge joints could shape itself into a loop and move by rolling like a self-propelled tank tread; then break open the loop to form a serpentine configuration and slither under or over obstacles; and then rearrange its modules to "morph" into a multilegged spider, able to stride over rocks and bumpy terrain. This robot, dubbed PolyBot, is being built and experimented with at Xerox Palo Alto Research Center (PARC), in California. This paper describes the main features of PolyBot and how it works. Programming of PolyBot is also discussed
Comparison of Oral Hygiene Status and Relative Abundance of Periodontal Pathogens Between Individuals With and Without Intellectual Disabilities: a Cross-Sectional Study

Background: Studies have reported a high prevalence of periodontal disease in individuals with intellectual disability (ID). The aim of this study was to compare the relative abundance of periodontal pathogens (red, orange, yellow, purple, and green complexes) between individuals with ID and healthy controls.Methods: Of the 31 subjects enrolled in this study, 16 with severe ID were selected from the outpatient clinic of the Special Care Dentistry of Hiroshima University Hospital, and 14 healthy subjects were selected from the outpatient clinic of another department at the same hospital. Dental plaque was sampled after oral examination. Decayed, missing, and filled permanent teeth (DMFT) counts were obtained and periodontal measurements were taken using the papillary-marginal-attached (PMA) index, plaque index (PI), gingival index (GI), and probing depth (PD). Gene sequencing (16S rRNA) was performed for each sample using next-generation high-throughput sequencing methods. The relative abundance of the periodontal pathogens and the clinical parameters were compared. An unpaired t-test was used to compare the oral health status in both groups and analysis of covariance was performed to compare the relative abundance of each pathogen.Results: No statistically significant difference in DMFT was observed between the two groups. However, significant differences in the median PMA index, PI, and GI were noted between the groups (P < 0.0001). In addition, the mean PD in the ID group was significantly higher than that in the control group (P < 0.0001). The relative abundances of Tannerella spp. and Treponema spp. were significantly higher in the ID group when compared to the control group at the genus level (P = 0.0383 and 0.0432, respectively); alternatively, the relative abundance of Porphyromonas spp. was significantly lower in the ID group (P < 0.0001). Conclusions: The PMA index, PI, GI, and PD were significantly lower in the ID group than in the control group. On the other hand, no significant difference in DMFT was observed between the two groups. Furthermore, our findings indicate that Tannerella forsythia might be more closely associated with periodontal disease than Porphyromonas gingivalis in individuals with ID.
Evaluation of Adolescents with Chronic Illness Knowledge and Attitudes about Health Promotion in Baghdad City: A Cross-sectional Study

Objective(s): To evaluate adolescents with chronic illness knowledge and attitudes about health promotion and to compare between them with respect to their knowledge and attitudes about health promotion in Baghdad City.A cross-sectional design is employed to evaluate adolescents with chronic illness knowledge and attitudes about health promotion and to compare between these adolescents’ knowledge and attitudes about health promotion for the period of November 3 rd 2018 to April 8 th 2019. Purposive, non-probability, sample of (137) adolescent is recruited for the present study. An evaluation tools are constructed for the purpose of the study. Reliability and validity of the study instrument is determined through pilot study. Data are collected through the use of constructed questionnaires and the application of the interview technique as means for data collection. Data are analysed through the application of descriptive statistical data analysis approach of total scores and range and inferential statistical data analysis approach of analysis of variance. The study indicates that that most of the early age adolescents have fair level of knowledge about health promotion and most of the middle and early age groups have good level of knowledge about health promotion.