Miracle-dz/UniFAR-FTUs huggingface dataset:
Metabolomic profiles and pathogenesis of nephrolithiasis

Purpose of review Kidney stone disease is caused by supersaturation of urine with certain metabolites and minerals. The urine composition of stone formers has been measured to prevent stone recurrence, specifically calcium, uric acid, oxalate, ammonia, citrate. However, these minerals and metabolites have proven to be unreliable in predicting stone recurrence. Metabolomics using high throughput technologies in well defined patient cohorts can identify metabolites that may provide insight into the pathogenesis of stones as well as offer possibilities in therapeutics. Recent findings Techniques including 1H-NMR, and liquid chromatography paired with tandem mass spectroscopy have identified multiple possible metabolites involved in stone formation. Compared to formers of calcium oxalate stones, healthy controls had higher levels of hippuric acid as well as metabolites involved in caffeine metabolism. Both the gut and urine microbiome may contribute to the altered metabolome of stone formers. Summary Although metabolomics has offered several potential metabolites that may be protective against or promote stone formation, the mechanisms behind these metabolomic profiles and their clinical significance requires further investigation.
Arabic Character Recognition Using Fractal Dimension

In this work the concepts of the pattern recognition was used to recognize printed Arabic characters, and the Fractal geometric dimension method was used. The input for the system is image, with bitmap format , then the image of character is recognized, and after that it is feeding to the OCR system. A feature space containing the values of the fractal dimension for the letters of Arabic was constructed. These features were used in the recognition phase. In this phase a comparison was made between the values in the feature space and the values of the letter inputs to be recognized, the comparison was done by the minimum Euclidian distance. Results of this work are 75% succeeded. and Matlab 6.5 is used to write the functions and subroutines for this work.
Infrared and microwave drying methods on the rehydration behaviour and mass transfer diffusion coefficient of Loligo Vulgaris

In this study, the effect of various drying methods on the rehydration behaviour and mass transfer diffusion coefficients of squid ( Loligo vulgaris ) is investigated. Drying methods were selected as infrared (IR), ultrasonic pre-treated infrared (US-IR) and microwave (MW). In IR and US-IR method drying temperatures were within 60 – 80 °C and in MW drying the power levels were in between 140 – 350 W. The rehydration process was carried out for all samples in 180 minutes at room temperature with 30-minute weighing intervals. Obtained rehydration data were applied to the mathematical models of Peleg and Two-Term Exponential. The rehydration ratios were changed between 1.78 – 2.50, 1.91 – 2.66 and 2.78 – 3.83 g/g dry matter for IR, US-IR, and MW respectively. Mass transfer diffusion coefficients of effective moisture diffusion (D eff ) values were changed between 1.01 × 10 -7 – 1.07 × 10 -7 , 1.02 × 10 -7 – 1.08 × 10 -7 , and 1.12 × 10 -7 – 1.22 × 10 -7 m 2 /s, for IR, US-IR, and MW respectively. Peleg and Two-Term Exponential mathematical models showed matched well with the experimental data. In addition, colour values found to be changed particularly in the brightness values due to rehydration process.
Automatizált, állókép alapú forgalom-számlálás erdészeti utakon

Az erdészeti utak nemcsak a faanyagszállítást, hanem általánosságban az erdő megközelítését szolgálják. Az úthasználóknak különböző, sokszor egymással ellentétes igénye van az úthálózattal szemben. A hálózat kezelőjének elemi érdeke, hogy az utakon áthaladó forgalomról és az úthasználók igényeiről minél több információval rendelkezzen. Az információk birtokában ugyanis megalapozott forgalomkezelést folytathat annak érdekében, hogy az erdészeti úthálózat a lehető legtöbb funkcióját ellássa.
Structural Basis for Speciﬁcity in the Poxvirus Topoisomerase

Summary Although smallpox has been eradicated from the human population, it is presently feared as a possible agent of bioterrorism. The smallpox virus codes for its own topoisomerase enzyme that differs from its cellular counterpart by requiring a speciﬁc DNA sequence for activation of catalysis. Here we present crystal structures of the smallpox virus topoisomerase enzyme bound both covalently and noncovalently to a speciﬁc DNA sequence. These structures reveal the basis for site-speciﬁc DNA recognition, and they explain how catalysis is likely activated by formation of a speciﬁc enzyme-DNA interface. Unexpectedly, thepoxvirusenzymeusesamajorgroovebinding a helix that is not present in the human enzyme to recognize part of the core recognition sequence and activate the enzyme for catalysis. The topoisomerase-DNA complex structures also provide a three-dimensional framework that may facilitate the rational design of therapeutic agents to treat poxvirus infections.
The Dimensionality of Inference Making: Are Local and Global Inferences Distinguishable?

ABSTRACT We investigated the dimensionality of inference making in samples of 4- to 9-year-olds (Ns = 416–783) to determine if local and global coherence inferences could be distinguished. In addition, we examined the validity of our experimenter-developed inference measure by comparing with three additional measures of listening comprehension. Multitrait, multimethod modeling determined that the best fitting model included both text and inference factors, but the factor loadings of these final models showed that local and global inference factors could not be measured reliably. The Inference Task as a whole was reliable and showed good validity at all grade levels.
Azolla: An alternative feed for sustainable livestock production

This review paper aims to analyse the possibility of Azolla as an alternative feed source for livestock and poultry production. The manuscript has been prepared by reviewing a plethora of available literatures related to this topic. The report of 20 th livestock census-2019 states that, India holds around 20% of world’s livestock population, which is precisely 535.82 million. The population has increased by 4.6% than previous livestock census-2012. Feed and fodder are the basis of existence of livestock and birds. The feed cost alone accounts around 70% of the total cost of livestock production. In a first changing world, the prices of animal feed i.e. both green fodder and concentrate are increasing day by day. Keeping this in mind, it is imperative to find an alternative feed source which will economise the cost of production and will be helpful towards a sustainable livestock and poultry production. Azolla is a fern that grows faster in fresh water in both temperate and tropical countries. It can be fed to various livestock and poultry birds without any deleterious effects. Various studies have reported that there was an overall increase of 15-20% milk yield in cattle and buffalo upon feeding of 1.5-2 Kg of Azolla in combination with daily ration. In case of meat animals and birds like pigs, rabbits, sheep, goats, ducks, quails, chickens etc., improved growth performances have been reported, indicating the possibility of using Azolla as a feed ingredient.
Conservation of Resources Theory Interpretation of Co-Destructed After-sales Service Encounters

Abstract The current study investigates the consumers’ co-destructed experiences with after-sales services (AS) through the lens of Conservation of Resources (COR) theory and Service Dominant Logic. The research is carried out in two phases. First, a qualitative study is conducted by analyzing consumer stories about co-destructed AS experiences with data collected from a public complaint website and three focus group interviews. Second, the proposed model is empirically tested on 207 consumer responses collected through a survey. The results reveal different paths on which consumers’ secondary losses either lead to low AS satisfaction or punitive behaviors after experiencing a co-destructed AS interaction.
Persistent Cardioactive Glycosides Intoxication Related to Gastric Phytobezoar of Oleander Leaves

Nerium oleander is a plant containing cardiac glycosides, and intoxication with its leaves is a medical emergency. We report the case of a 73-year-old man who took a decoction of oleander leaves for a reckless purpose. Upon arrival in the emergency room, he presented an altered state of consciousness, drooling and vomiting. He was bradycardic with intermittent third-degree atrioventricular block and typical downsloping ST-segment depression related to glycosides toxicity. Despite initial treatment with atropine, isoprenaline and repeated bolus of digoxin-specific antibody (Fab) fragments, symptoms were persistent 12 hours after admission. Suspecting that the patient not only drank the decoction but also ingested the leaves and had slow gastric emptying, we performed gastric lavage without benefit. We subsequently performed a gastroscopy that showed an oleander phytobezoar, and its removal permitted a rapid clinical improvement. Treatment with digoxin-specific antibodies for intoxication is well described and dosage should be adapted to the plasmatic level. Such an examination is useless in oleander intoxication because it does not represent the real quantity of toxin. The dosage of antibodies is empiric and should be guided by the clinical severity. In such intoxication, the presence of a phytobezoar from oleander leaves cannot be excluded so we believe that a gastroscopy for its mechanical removal should always be considered to avoid persistent release of toxin. LEARNING POINTS Ingestion of any part of the oleander plant can result in a severe cardioactive glycoside intoxication with potentially fatal arrhythmia and should be considered a medical emergency. Treatment consists of supportive care, correction of arrhythmias and electrolyte imbalance, and digoxin-specific antibody (Fab) fragments administration. Gastroscopy for mechanical removal of a phytobezoar responsible of persistent toxin release should be always considered.
Experimental evaluation of signal-to-noise in spectro-holography via modified uniformly redundant arrays in the soft x-ray and extreme ultraviolet spectral regime

We present dichroic x-ray lensless magnetic imaging by Fourier transform holography with an extended reference scheme via a modified uniformly redundant array (mURA). Holographic images of magnetic domains simultaneously generated by a single pinhole reference as well as by a mURA reference are compared with respect to the signal-to-noise ratio (SNR) as a function of exposure time. We apply this approach for spectro-holographic imaging of ferromagnetic domain patterns in Co/Pt multilayer films. Soft x-rays with wavelengths of 1.59 nm (Co L3 absorption edge) and 20.8 nm (Co M2,3 absorption edges) are used for image formation and to generate contrast via x-ray magnetic circular dichroism. For a given exposure time, the mURA-based holography allows to decouple the reconstruction SNR from the spatial resolution. For 1.59 nm wavelength, the reconstruction via the extended reference scheme shows no significant loss of spatial resolution compared to the single pinhole reference. In contrast, at 20.8 nm wavelength the single pinhole reveals some very intricate features which are lost in the image generated by the mURA, although overall a high-quality image is generated. The SNR-advantage of the mURA scheme is most notable when the hologram has to be encoded with few photons, while errors associated with the increased complexity of the reconstruction process reduce the advantage for high-photon-number experiments.
Chromatin Morphology in Human Germinal Vesicle Oocytes and Their Competence to Mature in Stimulated Cycles

The search for simple morphological predictors of oocyte quality is an important task for assisted reproduction technologies (ARTs). One such predictor may be the morphology of the oocyte nucleus, called the germinal vesicle (GV), including the level of chromatin aggregation around the atypical nucleolus (ANu)—a peculiar nuclear organelle, formerly referred to as the nucleolus-like body. A prospective cohort study allowed distinguishing three classes of GV oocytes among 135 oocytes retrieved from 64 patients: with a non-surrounded ANu and rare chromatin blocks in the nucleoplasm (Class A), with a complete peri-ANu heterochromatic rim assembling all chromatin (Class C), and intermediate variants (Class B). Comparison of the chromatin state and the ability of oocytes to complete meiosis allowed us to conclude that Class B and C oocytes are more capable of resuming meiosis in vitro and completing the first meiotic division, while Class A oocytes can resume maturation but often stop their development either at metaphase I (MI arrest) or before the onset of GV breakdown (GVBD arrest). In addition, oocytes with a low chromatin condensation demonstrated a high level of aneuploidy during the resumption of meiosis. Considering that the degree of chromatin condensation/compaction can be determined in vivo under a light microscope, this characteristic of the GV can be considered a promising criterion for selecting the best-quality GV oocytes in IVM rescue programs.
Judges' Considerations In Implementing Criminal Sanctions To Persons Of The Crime For Forcing Children To Perform Abusive Actions (Decision Number: 150/Pid.Sus/2021/PN Gdt)

Abstract One example of the crime of forcing a child to commit obscene acts is based on Decision Number: 150/Pid.Sus/2021/PN Gdt which states that the Defendant Nuzul Hairi Bin Nurul Huda has been legally and convincingly proven guilty of committing a crime of committing violence and threats of forceful violence child commits obscene acts. Factors that cause perpetrators to commit crimes of forcing children to commit obscene acts based on Decision Number: 150/Pid.Sus/2021/PN Gdt are educational factors, environmental factors or place of residence. The criminal act of sexual intercourse with a child in the jurisdiction of the Pesawaran Resort Police is indicated by the process of development of culture and civilization. Displacement of norms of behavior in western cultural areas and studied as a mental conflict or as a clash of cultural values. Economic factor theory is fundamental to all social structures. Economic development in the jurisdiction of the Pesawaran Resort Police tends to be uneven, there are still many people who have not found work or are unemployed. This condition causes social deviations in society, such as the crime of sexual intercourse with a child in the jurisdiction of the Pesawaran Resort Police. The judge's considerations in applying criminal sanctions to perpetrators of the crime of forcing children to commit obscene acts based on Decision Number: 150/Pid.Sus/2021/PN Gdt consist of 2 (two) things, namely aggravating things and mitigating things. What was aggravating was that the actions of the defendant had damaged the future of the witness-victim, the parents of the witness-victim felt very objection to the actions of the defendant, and the actions of the defendant had violated religious norms. Meanwhile, the mitigating factors are that the defendant admits and regrets his actions and promises not to repeat his actions, and the defendant has never been punished.
A REVIEW ON BLUETOOTH LOW ENERGY ENABLED DOOR LOCKING SYSTEMS

The Business market for smart phone applications using Bluetooth Low Energy (BLE) is constantly amplifying nowadays. The Bluetooth Special Interest Groups (SIG) expected that in future they will encounter more than 90 percent of all Bluetooth enabled devices which supports BLE systems. Bluetooth Low Energy is becoming progressively popular in smart phone applications due to the circumstance of using it for the proximity data. This project gauges the Bluetooth Low Energy in the context of using mobile applications to unlock a door automatically when an intruder approaches the door. Computations were performed to determine the reliability, signal strength, connection latency and energy consumption for the same. The hardware designed for this door lock system is the union of components like a Bluetooth module to act as a command agent, an android mobile phone which functions as the task master, an Arduino microcontroller to process the data or to operate as a control center and a solenoid as a output for the door lock system. All of the tests stipulated above will go according to the initial design of this research.This paper provides a insight on various available security system
The Role of MicroRNAs in Development of Endometrial Cancer: A Literature Review

Endometrial cancer (EC) ranks as the second most common gynaecological cancer worldwide. EC patients are diagnosed at an early clinical stage and generally have a good prognosis. Therefore, there is a dire need for development of a specific marker for early detection of endometrial adenocarcinoma. The development of EC is conditioned by a multistep process of oncogenic upregulation and tumor suppressor downregulation as shown by molecular genetic evidence. In this setting, microRNAs appear as significant regulators of gene expression and several variations in the expression of microRNAs have been implicated in normal endometrium, endometrial tissue, metrorrhagia, and endometrial cancer. Furthermore, microRNAs act as highly precise, sensitive, and robust molecules, making them potential markers for diagnosing specific cancers and their progression. With the rising incidence of EC, its management remains a vexing challenge and diagnostic methods for the disease are limited to invasive, expensive, and inaccurate tools. Therefore, the prospect of exploiting the utility of microRNAs as potential candidates for diagnosis and therapeutic use in EC seems promising.
End-to-End Multi-Target Verification Environment for a RISC-V Microprocessor

In this paper, we present the end-to-end verification environment developed for verifying A-Core, a custom, extensible and configurable RISC-V microprocessor targeted for controlling communication, cryptography, and machine learning hardware accelerators. The developed open source verification environment utilizes a Python-based ASIC-generic system verification framework. In the developed environment, the processor can be verified with self-checking user-written Assembly- or C-programs, providing a seamless from-C-to-hardware verification methodology. With the presented test platform, test programs can be run on various targets: RTL simulation, FPGA, or ASIC, providing one verification environment for all maturity levels of the design. The platform enables end-to-end testing: verification of the functionality of the A-Core ASIC from the programming sequence over a JTAG interface to printouts over UART, providing tests coverage also for real use cases of the hardware. Performance metrics for different sized test programs are provided to enable characterization of the speed of verification.
Realizing frequency reconfigurable antenna by ferrite‐loaded half‐mode SIW

We propose and experimentally demonstrate a frequency reconfigurable antenna using ferrite loaded half‐mode substrate integrated waveguide (SIW). The antenna design is based on a SIW cavity with an embedded ferrite slab, which causes the resonant frequency of the cavity tunable under bias magnetic field. The antenna features omni‐direction radiation and small size. A prototype antenna is designed and fabricated. The measurements show the tunable frequency bandwidth is over 11% covering frequencies 5.04–5.62 GHz in low bias magnetic field region, and 5% covering 4.28–4.5 GHz in high bias magnetic field region. The measurement is in good agreement with simulations. The gain of antenna is all over 1.6 dBi, and the frequency reconfiguration does not affect the radiation pattern of the antenna, providing a preferable feature for frequency reconfigurable antenna. This type of antenna may be a good candidate for practical applications such as base stations and satellites. © 2017 Wiley Periodicals, Inc. Microwave Opt Technol Lett 59:1365–1371, 2017
The Effect of Biomimetic Remineralization of Calcium Phosphate Ion Clusters-Treated Enamel Surfaces on Bracket Shear Bond Strength

Purpose To evaluate the remineralization effect of calcium phosphate ion clusters (CPICs) on demineralized enamel surfaces and their effects on bracket shear bond strength. Patients and Methods Extracted premolars were prepared in resin blocks. The samples in the form of resin blocks were divided into five experimental groups: control group, demineralized group, and groups of CPIC solution treatment for 30, 60, and 90s. The specimens were examined using scanning electron microscopy (SEM), energy-dispersive spectroscopy (EDX), microhardness testing, micro-computed tomography (micro-CT) assessment, shear bond strength (SBS) test, and adhesive remnant index (ARI) score. Results The SEM images revealed epitaxial growth of enamel and a decrease in the thickness of the demineralized enamel layer when treated with CPIC solution. The EDX analysis revealed an increase in the Ca/P ratio in the CPIC-treated groups. The microhardness value significantly increased when treated with CPICs; however, it showed a lower value than that of the sound enamel groups. As a result of the micro-CT test, radiolucency decreased gradually as the CPIC treatment time increased. The SBS test and ARI score results showed an improvement in bonding stability after treatment with CPICs. Conclusion We demonstrated an enamel biomodification approach using CPIC solution treatment, which is a promising strategy for enamel remineralization. Specifically, remineralization of demineralized enamel improves the orthodontic bracket SBS.
Integrated optical fiber amplifiers for space-division multiplexed systems

Integrated space-division multiplexed (SDM) erbium-doped fiber amplifiers (EDFAs) are not only inevitable for SDM systems, but can be an alternative solution to nowadays EDFA array for parallel amplification. SDM EDFAs are expected to provide substantial complexity and cost savings through spatial-integration compared to duplicating single-mode fiber amplifiers. High output power and low noise figure can be achieved by cladding-pumped SDM EDFAs. In this paper, different cladding pumping solutions, cladding-pumped single-mode and multimode multi-core EDFAs will be discussed.