Miracle-dz/UniFAR-FTUs huggingface dataset:
Determination of carotenoids in extracts from species of Tagetes and Calendula

Background : Carotenoids have played a significant role in reducing the risk of chronic diseases. The most studied in this regard is β-carotene, present in species of Tagetes and Calendula genus. Objective of the study: Comparative analysis of β-carotene content in liquid and dry flowers extracts of Tagetes and Calendula species, cultivated in the collection of the Scientific Center for the Cultivation of Medicinal Plants of Nicolae Testemitanu SUMPh. Material and methods : Dry extracts of flowers harvested in the budding-flowering phase, were obtained by repeated maceration and rotary evaporation, subjected to phytochemical evaluation by thin-layer chromatography (TLC) and UV-VIS spectrophotometry, equivalent to β-carotene. Results: Beta-carotene was identified by TLC in hexan-ethyl acetate (50:50, v/v), retention factors were established. Caratenoid content (mg%) varied as follows: in T. patula L . (75.34±2.15), T. erecta L . (21.97±0.84), C. officinalis L . variety Natali (13.09±3.23), C. officinalis L . variety Diana (12.39±1.98), C. officinalis L . local population (10.99±0.06). The carotenoids content ranged in the dry extracts as well, determined in the highest amount in T. patula L. flowers (137.87±2.18 mg%). Conclusions: This study demonstrated the opportunity for further research of Tagetes and Calendula varieties that could serve as sources of carotenoids for obtaining antioxidant phyto-pharmaceuticals.
The Effect of Heat Stress on the Metabolism of Dairy Cows: Updates & Review

With the intensification of the greenhouse effect and global warming, heat stress has become one of the most important factors that affect the profit in dairy industry production. In recent years, investigators have performed plenty of researches concerning metabolism of dairy cows under the heat stress. This article has reviewed the effect of heat stress on metabolism of lipid, carbohydrate, protein and energy in dairy cows and described several nutritional strategies to alleviate heat stress to reveal the underlying metabolic mechanism during heat stress and to provide references for exploring more effective measures to alleviate heat stress.
Structural Health Monitoring for the Advanced Maintenance of Wind Turbines: A review

— Wind energy has been developed rapidly throughout the world. However, as more wind parks are built worldwide, the number of accidents recorded regarding wind turbines increases as well. As the most critical and expensive components of the wind turbine system, wind turbine blades often suffer damage. Presently in situ blade inspection is carried out every 3 to 6 month visually or with manual operatives involved in dangerous abseiling. Only limited, crude repairs are performed in situ. In most cases a damaged blade is dismantled & transported to a factory with specialized composite repair facilities, making the operation downtime very high, especially with the increasing trend towards remote offshore location of turbines. These factors generate very high maintenance costs, amounting to over 30% of overall operating costs when allowing for lost revenue. The trend is for turbines to grow in size and number to the globally set targets and their deployment becomes more widespread and remote, maintenance costs will escalate. The ideal solution is for Structural Health Monitoring (SHM) of blades so as to minimize the need for extensive repairs, thus eliminating all transport costs and associated downtime. This review will underline the most promising emerging and established technologies on the topic.
Rhetorical Structures in Medication Information for Patients and Physicians -a comparative study in preparation for text generation

The healthcare domain contains a lot of information that could help patients understand and handle their situation, if it is presented in an understandable way. One way to assist healthcare professionals in this endeavour could be a text generation system that can handle a large amount of information and produce a text adapted to fit the knowledge and needs of the recipient. In order to construct such a system, the current methods for presenting and adapting texts in the healthcare domain need to be analysed and understood. In this study, Rhetorical Structure Theory is used, which is a framework that has often been applied within text generation to map out how texts are structured. The objective is to discern how texts containing medication information directed toward laymen are structured in comparison to similar texts directed toward healthcare professionals. It turns out that the texts directed toward laymen prompt and motivate the reader directly, while texts directed toward healthcare professionals at the utmost offer advice and generally provides more neutral, comprehensive information. The results indicate that Rhetorical Structure Theory can be used to find different intentions with texts directed toward different recipients, as well as how these intentions are mediated in the texts, in a structured way that appears to be useful for the text generation process.
HPV in sperm is efﬁciently removed by washing: A suitable approach for assisted reproduction

Research question: Is it possible to obtain HPV-free sperm cells to be employed in assisted reproduction from clinically HPV-positive men by sperm washing? Design: Observational study performed on HPV-positive patients. Freshly ejaculated sperm was collected, readily processed by gradient separation followed by swim-up from the washed pellet. The resulting fractions tested for the presence of HPV DNA. Results: Of the fifteen clinically HPV-positive subjects, 66% were positive in at least one of the seminal fractions. If any postivity was detected, plasma was always HPV-positive suggesting that HPV homes in seminal plasma. No consistent pattern was observed throughout different samples in cell pellet, round cells and non-motile sperm cells fractions. However, upon sperm-wash procedure, the fraction of motile sperm cells was never found HPV
Skin tear treatment and prevention by nurses: an integrative literature review

The objective of the present study was to identify scientific evidence in the literature regarding management and prevention of skin tears by nurses over the last ten years. This is an integrative review of articles found in the LILACS, SciELO, BDENF, MEDLINE, Scopus, ScienceDirect and PubMed databases, identified with the Portuguese, English and Spanish descriptors for "skin," "friction," or with the keyword "skin tears". After inclusion and exclusion criteria were applied, fifteen texts were selected. Scientific evidence demonstrated that the best management results are obtained by covering the tear with the skin flap itself, using octylcyanoacrylate or silicone-based products. Prevention consists of promoting a safe environment, through multidisciplinary work and health education. We conclude that it is the nursing staff's responsibility to avoid infection, trauma of any intensity, pain and bleeding.
An Overview of Medicinal Plants Possessing Wound Healing Activity: A Natural Effective Wound Healer

Wounds are the disruption of anatomical and efficient integrity of living tissue. Wound healing is a complicated and frequent cascade of events, with a range of cellular and biochemical procedures, eventually resulting in the rebuilding and revival of damaged tissue. Several herbs and medicinal plants proved to be a wound healer and formulated for treatment of wounds. Plants and their extracts have vast potential for the treatment of wounds. The phytomedicines for wound healing are not only cheap and affordable but are also safe as hyper sensitive reactions are rarely encountered with the use of these agents. Some of them are Aloe, Tulsi, Neem, Turmeric, Achiote, etc., are mostly used in all kinds of wounds. The pharmacological validation on Indian medicinal plants is very limited and a large number of plants used in tribal and folklore with enormous potential have not been validated for their wound healing activity. The review focused on the immense scope for researchers because the traditional claims and development is safe and effective and globally accepted herbal drugs for cuts and wounds. Hence, some common plants those are used in traditional medicine for the treatment of wounds. It is a beneficial work for researchers to provide details about the wound healing herbs and development of safe and effective herbal drugs for cuts and wounds.
International Journal of Hematology and Blood Research Anatomical-Physiological and Mathematical Justification of the New Principle of the Function of the Cardiovascular System and the Development of Cardiovascular Diseases

Anatomical features of the structure of the arteries and features of their functioning and mathematical research-allowed us to take a fresh look at the principle of the function of the cardiovascular system. The main role in transportation of blood to the capillary bed is played by the artery, the power of the heart is only 0,49-0,027% of the power needed to transport blood to the capillary bed. Vascular pump is regulated by the frequency of contractions of the heart muscle and is tightly synchronized with the work of the heart. The rapid spread of the pulse wave causes a suction effect. Following the reduction of the vessel wall, the blood is just drawn from the aorta and large arteries to the smaller vessels down to the capillary bed. Systematic irregularities in the vascular pump cause increased pressure in arteries located above the lesion and lead to the development of hypertension and can be a starting point in the development of various diseases of the cardiovascular system and other body systems. These illnesses may be both local and systemic, depending on the size and the location of pathological changes in the vascular wall.
Genome sequences of bacterial biocontrol agents isolated from Solanum lycopersicum and Medicago truncatula in Tunisia

The whole-genomes shotgun sequences of 6 bacterial biocontrol agents isolated from Medicago truncatula and Solanum lycopersicum collected in the North of Tunisia are presented in this study. The genome sequences supplement the existing genomics resources and give us an insight into the biodiversity of bacteria associated with plants and prospect key genes required for their endophytic behaviour, interactions with their hosts and biocontrol activity traits against plant pathogens.
Sampling rate influence in up and down mixing of QPSK and OFDM signals using an SOA‐MZI in a differential configuration

Up and down frequency conversions in the range of 0.5–39.5 GHz are performed by using a Semiconductor Optical Amplifier–Mach-Zehnder interferometer (SOA-MZI) in a differential configuration as a sampling mixer. The authors show that increasing the sampling frequency by a ratio of 2.5 (from 7.8 to 19.5 GHz) improves the efficiency and the quality of the optical transmission of QPSK and OFDM signals due to a better signal level and a lower aliased noise power when the sampling rate is higher. At the high sampling rate, the obtained EVM is sufficiently low for allowing data bit rates higher than 1 Gbit/s and 245 Mbit/s, respectively, for QPSK and OFDM modulated data.
A replicated object system

We describe Netfarm , a replicated object system, in which various kinds of objects can be stored across a network. These objects are instances of schemas (themselves also objects), which describe the representation of objects, and their behaviour, using a portable bytecode. Objects affect each other by running scripts using the bytecode, which in turn produce effects on multi-sets of computed values . Arbitrary access to effects is restricted by an object capability system on the object scale, and by capability lists on a larger scale, allowing untrusted objects to communicate, and for many untrusted applications to run on nodes and client programs. Objects may exist on multiple nodes of the network to make the system fault-tolerant, as their behaviour is explicated to the system and thus reproducible. Replication of the actions generated by scripts cause Netfarm to exhibit strong eventual consistency . This programming model allows for supporting many programs on one object system, which can use efficient replicated algorithms and data structures.
Compositional situation: analysis of the location of two sculptures in Mexico City

: The study consists of two parts. In the first one, the author outlines a methodological concept of researching the quality of compositional and artistic spatial systems that are created, for example, in the urban environment with the partic ipation of, inter alia, architectural objects and works of art. The subject of this type of research was called a ‘compositional situation’. In the second part, the author uses the proposed research method to analyze specific cases. These are two situ ations existing in the public spaces of Mexico City, in which sculptures of famous Mexican sculptor Sebastian were located.
FORMULATION AND IN-VITRO EVALUATION OF TACROLIMUS HYDROGEL

The aim of the present work was to formulate and evaluate formulation of Tacrolimus as oral hydrogel to improve the efficacy & bioavailability of Tacrolimus. Tacrolimus gel was prepared with Gellan gum and Carbopol 934P as gelling agents with polyethylene glycol as a penetration enhancer. The formulations were examined for pH, spreadability, consistency, viscosity, homogeneity, drug content and stability. In vitro drug release was evaluated using Franz diffusion cell. The viscosity of all formulation follows a pseudo-plastic flow behavior. The pH of formulation Lies in between 6.3to 7.2. The formulation F2 and F5 showed good released pattern. Tacrolimus is used in the treatment of eczema, in particular atopic dermatitis. It suppresses inflammation in a similar way to steroids, and is equally as effective as a mid-potency steroid. An important advantage of tacrolimus is that, unlike steroids, it does not cause skin thinning (atrophy), or other steroid related side effects.
ASSESSMENT OF KNOWLEDGE AND AWARENESS ON CERVICAL CANCER AMONG GRADUATING WOMEN IN AND AROUND WARANGAL CITY

According to world health organization (WHO) cervical cancer among women in world is fourth most frequent type of cancer and second most frequent among Indian women. Annually lakhs of new cases are being diagnosed mostly in advanced stages. Strikingly India stands 3 rd in accounting major cervical cancer deaths. This study was carried out for period of 6 months from June 2017 to November 2017 to assess the perception level of awareness and knowledge among graduating women in and around Warangal city regarding the otrocious disease, cervical cancer and causative virus human papilloma virus (HPV). A descriptive cross sectional study with the aid of self coded questionnaire-based survey was conducted involving 906 graduating respondents of various levels and out of 1050 questionnaires filled by respondents results were drawn from 906 questionnaire forms and rest 144 were excluded due to missing data. Only 31.2% (253) participants were aware of cervical cancer and only 16% of respondents reported HPV as a causative organism. 9.38% respondents were aware of Pap smear as a screening test for cervical cancer and 96 of 906 were aware of vaccination. Statistically results showed that there is significant relation between increasing age, level of education, occupation and living areas in getting aware of cervical cancer. With the study carried out in and around Warangal region a conclusion was drawn that cognizance is necessary for women of Warangal region in filling the serious breach and making them knowledgeable as poor awareness levels were marked.
Clinical occurrence and phenotypic features of sW172stop and sW172non-stop mutations caused by drug-resistance associated mutation of hepatitis B virus rtA181T

the profile of clinical occurrence and phenotypic features of sW172stop and sW172non-stop mutations caused by adefovir dipivoxil (ADV)-resistance-associated mutation rtA181T. Methods A total of 12,708 patients in Beijing 302 Hospital from July 2011 to July 2016 were enrolled in this study. Drug-resistance mutations in RT region and related mutations in S region were analyzed by direct sequencing. 1.1mer HBV replicons harboring various mutant RT/S gene mutations were constructed respectively for phenotypic analysis. Results The rtA181T mutation was detected in 504(3.97%) of the patients. Among them, 146 patients were detected with coexistence of primary adefovir-resistant mutations rtN236T and/or rtA181V. Most rtA181Ts simultaneously caused sW172stop mutation (409/504); while a few caused non-stop mutations sW172/L (29/504) and sW172/S(15/504), and coexistence of the stop and non-stop mutations were also detected (51/504). In ADV-resistant patients, rtA181Ts were frequently detected in concomitance with rtN236T mutation. Patients infected with rtA181T/sW172stop+N236T mutants had a significantly lower HBV DNA level than those with rtA181T/sW172L or S+N236T mutants (5.07 ± 1.79 vs. 3.63 ± 1.90 log 10 IU/ml, P =0.013). Phenotypic analysis showed that in replicon-transfected HepG2 cells, rtA181T/sW172stop+N236T mutants had undetectable supernatant HBsAg. In contrast, rtA181T/sW172L+N236T and rtA181T/sW172S+N236T mutants had slightly lower levels of HBsAg compared to wild-type; rtA181T/sW172stop+N236T mutants had a significantly lower replication capacity than 2 rtA181T/ sW172non-stop mutants, and half maximal eﬀective concentration of ADV were 3.69, 5.49, and 7.38 folds wild-type's levels, respectively. Conclusions When rtA181T and rtN236T coexisted. sW172 non-stop mutants, had higher replication capacity and ADV-resistant feature than sW172stop mutants, and is likely to cause higher level of virologic rebound in ADV-resistant patients.
Comparing symmetric and asymmetric volatility estimates for S&P index prices

In every parametric formula of pricing a financial instrument, factors used in the calculation generally include the volatility estimate. Volatility measures the likely changes of the price for a specific period of time. The accuracy of estimated price strongly relies on the accuracy of provided expected changes in the market volatility for the period of interest. As opposed to other variables, which are assigned values to financial instrument, volatility is the only estimated one. For that reason, big focus of researchers was and still is on improving the volatility estimate. Initiated are different estimation approaches through last few decades. This paper explains few ARCH models, symmetric and asymmetric, and compares their estimates of daily volatility for the Standard and Poor’s Indexes.
Long Noncoding RNA ST7-AS1 Upregulates TRPM7 Expression by Sponging microRNA-543 to Promote Cervical Cancer Progression

Purpose: ST7 antisense RNA 1 (ST7-AS1) is a long noncoding RNA that affects the progression of gastric cancer and laryngeal squamous cell carcinoma. Herein, ST7-AS1 expression was detected in cervical cancer tissues and cell lines. In addition, its biological roles in inducing the aggressive phenotype of cervical cancer and its associated mechanisms of action were illustrated. Patients and Methods: ST7-AS1 expression in cervical cancer tissues and cell lines was detected using quantitative real-time polymerase chain reaction (qRT-PCR). Malignancy was determined using Cell Counting Kit-8 assay, ﬂ ow cytometry, transwell migration and invasion assays, and xenograft experiments. Bioinformatics analysis was performed to predict the interaction between ST7-AS1 and microRNA-543 (miR-543). Luciferase reporter assay, RNA immunoprecipitation assay, Western blotting, qRT-PCR, and rescue experiments were performed to further identify the interactions among ST7-AS1, miR-543, and transient receptor potential melastatin 7 (TRPM7). Results: ST7-AS1 was upregulated in cervical cancer tissues and cell lines. ST7-AS1 overexpression was correlated with a high International Federation of Gynecology and Obstetrics stage, frequent lymph node metastasis, deep cervical invasion, and short overall survival in patients with cervical cancer. ST7-AS1 inhibition hindered cervical cancer cell proliferation, migration, and invasion; ST7-AS1 downregulation resulted in marked cell apoptosis. Additionally, ST7-AS1 de ﬁ ciency restricted cervical tumor growth in vivo. Mechanistically, ST7-AS1 functioned as competing endogenous RNA to increase TRPM7 expression by sponging miR-543. Intriguingly, rescue experiments revealed that miR-543 downregulation or TRPM7 overexpression abrogated the inhibitory actions of ST7-AS1 knockdown in the aggressive phenotype of cervical cancer cells. Conclusion: The newly identi ﬁ ed ST7-AS1/miR-543/TRPM7 axis promoted the oncogeni-city of cervical cancer cells both in vitro and in vivo. Our study highlighted the importance of this novel axis in cervical cancer progression, suggesting that this pathway can serve as a promising therapeutic target for cervical cancer.
Ultra-wideband Indoor Positioning Based on Triangle Midpoint Algorithm

—In this paper, we present an experimental indoor positioning system consisting of three anchor nodes and a tag, which uses a microprocessor with an ultra-wideband wireless transceiver device. The scheme based on the time-of-arrival technique and triangle midpoint algorithm provides accurate localization in a limited indoor area. The average localization error of the proposed positioning system placed in the indoor space of 732cm×488cm×220cm is 12.87cm. The experimental results demonstrated that the proposed system has the characteristics of high precision localization and less computation time.