Miracle-dz/UniFAR-FTUs huggingface dataset:
Interannual Variations of Surface Currents and Transports in the Sicily Channel Derived From Coastal Altimetry Geophysical Oceans

A 20 year coastal altimetry data set (X-TRACK) is used, for the ﬁrst time, to gain insight into the long-term interannual variations of the surface circulation in the Sicily Channel. First, a spectral along with a time/space diagram analysis are applied to the monthly means. They reveal a regionally coherent current patterns from track to track with a marked interannual variability that is unequally shared between the Atlantic Tunisian Current and Atlantic Ionian Stream inﬂows in the Sicily Channel and the Bifurcation Tyrrhenian Current outﬂow northeast of Sicily. Second, an empirical altimetry-based transport-like technique is proposed to quantify volume budgets inside the closed boxes formed by the crossing of the altimetry tracks and coastlines over the study area. A set of hydrographic measurements is used to validate the method. The inferred altimetry transports give a well-balanced mean eastward Atlantic Waters baroclinic ﬂow of 0.4 Sv and standard deviations of 0.2 Sv on a yearly basis throughout the Sicily Channel and toward the Ionian Sea, which is fairly coherent with those found in the literature. Furthermore, the analysis allows to quantify the intrusions of Atlantic Waters over the Tunisian Shelf (0.12 6 0.1 Sv) and highlights two main modes of variability of the main surface waters path over the Sicily Channel through the Bifurcation Atlantic Tunisian Current and Atlantic Ionian Stream systems. Some physical mechanisms are ﬁnally discussed with regards to changes in the observed currents and transports.
Hepatitis A virus and environmental quality indicators in aquatic ecosystems for oyster farming in the Northeast of the State of Pará, Brazil

- Research into the occurrence of microbiological contaminants, including hepatitis A virus (HAV), in river waters intended for oyster farming is of extreme importance for public health. This study aimed to detect the occurrence of HAV in the aquatic environment for ostreiculture in northeastern Pará, Brazil, and correlate with microbiological, physico-chemical and climatological variables. The HAV research was based on the method of water concentration by filtration membrane adsorption-elution and in the organic flocculation method with skim milk, followed by Nested-PCR. Quantification of coliforms, Enterococci and heterotrophic bacteria was performed. The physico-chemical variables were measured with multiparametric probe and spectrophotometry. Positive samples were purified and submitted to sequencing. From March 2017 to December 2018, 203 samples of river water were collected and analyzed in the municipalities of Augusto Corrêa, Curuçá, Salinópolis and São Caetano de Odivelas. In 10.8% of the analyzed samples the HAV RNA was detected, in all localities the HAV was classified in genotype IB. There was no significant difference between the concentration methods of the water samples. The only physicochemical variable that most influenced HAV detection was dissolved oxygen. Regarding the bacterial indicators, the highest statistical significance occurred with thermotolerant coliforms and Escherichia coli. The detection of HAV in the four municipalities studied shows that the virus is circulating in the aquatic environment and, therefore, in the community. In this context, more effective hygienic-sanitary measures are necessary in these communities dedicated to oyster farming.
A CENTRAL LIMIT THEOREM FOR THE OVERLAP IN THE HOPFIELD MODEL 1

We consider the Hop(cid:12)eld model with n neurons and an increasing number p D p (cid:144) n (cid:145) of randomly chosen patterns. Under the condition (cid:144) p 3 log p (cid:145) =n ! 0, we prove for every (cid:12)xed choice of overlap parameters a central limit theorem as n ! 1 , which holds for almost all realizations of the random patterns. In the special case where the temperature is above the critical one and there is no external magnetic (cid:12)eld, the condition (cid:144) p 2 log p (cid:145) =n ! 0 suf(cid:12)ces. As in the case of a (cid:12)nite number of patterns, the central limit theorem requires a centering which depends on the random patterns.
The Old World and New World Alphaviruses Use Different Virus-Speciﬁc Proteins for Induction of Transcriptional Shutoff (cid:1)

Alphaviruses are widely distributed throughout the world. During the last few thousand years, the New World viruses, including Venezuelan equine encephalitis virus (VEEV) and eastern equine encephalitis virus (EEEV), evolved separately from those of the Old World, i.e., Sindbis virus (SINV) and Semliki Forest virus (SFV). Nevertheless, the results of our study indicate that both groups have developed the same characteristic: their replication efﬁciently interferes with cellular transcription and the cell response to virus replication. Transcriptional shutoff caused by at least two of the Old World alphaviruses, SINV and SFV, which belong to different serological complexes, depends on nsP2, but not on the capsid protein, functioning. Our data suggest that the New World alphaviruses VEEV and EEEV developed an alternative mechanism of transcription inhibition that is mainly determined by their capsid protein, but not by the nsP2. The ability of the VEEV capsid to inhibit cellular transcription appears to be controlled by the amino-terminal fragment of the protein, but not by its protease activity or by the positively charged RNA-binding domain. These data provide new insights into alphavirus
Intensive Care Paramedic Skills in the Management of Major Trauma – Effect on Mortality in an Informal, Two-Tiered, Decentralised State-Wide Trauma System

Background: A number of studies have attempted to determine the value of pre-hospital Advanced Life Support (ALS) interventions in trauma patients. Few of these studies provide enough detail of the scope of advanced skills performed, the education/training arrangements in which these skills have been learned, the pre-ALS educational platform training, or the organizational arrangements in which paramedics respond to enable comparison of like with like services. Combined, these factors provide a significant challenge to interpretation of the findings and the utility of extrapolating the results to other operational settings. In many published reports, survival to discharge is the outcome of interest and rarely are there analyses of the effectiveness of ALS interventions on survival benefit across the patients entire care pathway. We sought to examine whether or not the training of Intensive Care Paramedics in Queensland had resulted in improved survival, at any point in the care trajectory, for major trauma patients. Method: Retrospective linked analysis of routinely collected emergency prehospital clinical records, inpatient records and death registry data was conducted for all-age, all-cause major trauma for the four-year period 1998-2001. The key outcomes of interest were survival to hospital, survival to discharge or 30 days post discharge; and survival overall. Binomial logistic regression, controlled for GCS less than 9, age, sex and the presence or absence of co-morbidities, was employed to determine the relationship between advanced life support interventions performed by Intensive Care Paramedics and survival from major trauma. Results: Between 1998 and 2001, Intensive Care Paramedics in Queensland attended approximately one quarter (24.4%; n=5, 481) of major trauma cases (N= 22, 463). Patients experiencing a major trauma and who are attended by Intensive Care Paramedics had a statistically significant higher prehospital survival probability at all times (OR 1.16; 95%CI 1.02-1.39) but were more likely to die in hospital (OR 0.69; 95% CI 0.58-0.80). Overall mortality however, when controlled for GCS <9, age, sex and co-morbidities, was not significantly reduced by the presence of Intensive Care Paramedics (OR 1.05; 95%CI 0.95-1.16). Conclusion: The standard of advanced skill training in Queensland provides a pre-hospital survival benefit to major trauma patients in the State; however this effect is not sustained across the care continuum. We were not able to determine from this data whether this was a consequence of the resuscitation of patients who would inevitably die from catastrophic injuries or who succumbed later in their patient career as a result of end-organ damage and/or systemic infection.
Laparoskopik Kolesistektomiden Sonra Nontüberküloz Mikobakteriyel Giri ş Yeri Enfeksiyonu [Port-site Non-tuberculous Mycobacterial Infection after Laparoscopic Cholecystectomy: A Case Series Study]

SUMMARY Port-site infection by mycobacterial organism is an unusual complication. This article aims to report the occurrence of port-site mycobacterial infection after laparoscopic cholecystectomy and to describe the diagnostic and therapeutic tools of this unusual complication. This case series study included 7 cases presented by port-site unhealed sinuses after laparoscopic cholecystectomy in Al-Azhar University hospital, Cairo, Egypt. Two methods were used to confirm the diagnosis; the bacteriological diagnosis by culture of pus collected from the port-site and histopathological examination of specimens after resection of port-site unhealed sinuses. Bacteriological and histopathological examinations showed the presence of mycobacterial infection in 4 cases. There was a special characteristic picture on sinogram and during surgical excision of the sinuses. All cases cured by meticulous surgery followed by anti-mycobacterial medications. Mycobacterial infection may be one of the causes of port-site delayed wound healing and the treatment should mainly depend on good meticulous surgical excision.
A Novel Approach for Detecting Network Intrusion Using Genetic Network Programming and Fuzzy Class Association Rule Mining

As the internet services spread all over the world, many kinds of security threats are increasing. Therefore, intrusion detection systems are effectively used for detecting intrusion accesses. A new approach is proposed called a fuzzy class-association rule mining (FCRM) method based on genetic network programming (GNP) for detecting network intrusions and help IDS to achieve higher accuracy in detection and less positive false ratio. The general procedure of proposed method is as follows: Firstly the fuzzy rule extraction is done using fuzzy membership values, and use of sub attributes method is used to avoid the information loss. By combining fuzzy set theory with GNP, the system deals with the mixed database that contains both isolated and constant attributes and also extract many important class association rules that improve the detection ability. After the withdrawal of class-association rules, categorization is done using these rules. Finally two kinds of classifiers are built up for misuse detection and anomaly detection in order to categorize new data correctly. Therefore, the proposed system is flexibly applied to both misuse and anomaly detection in intrusion detection issues.
Aﬃne Nash groups over real closed ﬁelds

We prove that a semialgebraically connected aﬃne Nash group over a real closed ﬁeld R is Nash isogenous to the semialgebraically connected component of the group H ( R ) of R -points of some algebraic group H deﬁned over R . In the case when R = R this result was claimed in [5], but a mistake in the proof was recently found, and the new proof we obtained has the advantage of being valid over an arbitrary real closed ﬁeld. We also extend the result to not necessarily connected aﬃne Nash groups over arbitrary real closed ﬁelds.
A method for separating Antarctic postglacial rebound and ice mass balance using future ICESat Geoscience Laser Altimeter System, Gravity Recovery and Climate Experiment, and data

[ 1 ] Measurements of ice elevation from the Geoscience Laser Altimeter System (GLAS) aboard the Ice, Cloud, and Land Elevation Satellite can be combined with time-variable geoid measurements from the Gravity Recovery and Climate Experiment (GRACE) satellite mission to learn about ongoing changes in polar ice mass and viscoelastic rebound of the lithosphere under the ice sheet. We estimate the accuracy in recovering the spatially varying ice mass trend and postglacial rebound signals for Antarctica, from combining 5 years of simulated GRACE and GLAS data. We obtain root-mean square accuracies of 5.3 and 19.9 mm yr (cid:1) 1 for postglacial rebound and ice mass trend, respectively, when smoothed over 250 km scales. The largest source of error in the combined signals is the effect of the unknown time-variable accumulation on the density of the ice column. To estimate this contribution and so obtain better estimates of ice mass trend and postglacial rebound, we add Global Positioning System (GPS) measurements of vertical velocities as additional constraints. Using an empirical relation between the errors in postglacial rebound and ice mass trend that result from the unknown density variation within the ice column, we are able to solve for all three unknowns in the problem: ice mass trend, postglacial rebound, and the snow compaction trend. The addition of a plausible distribution of GPS measurements reduces the errors in estimates of postglacial rebound and ice mass trend to 3.4 and 15.9 mm yr (cid:1) 1 , respectively. GRACE, Antarctica, postglacial rebound, ice mass imbalance, altimeter, GPS Citation:
in Computer

— 3GPP LTE (Third Generation Partnership project Long Term Evolution) is introduced with new architecture and features, to meet user’s high data rate demand for a long term in the future. 3GPP LTE/SAE is a next generation radio access system that supports future end-user requirements. The aim of LTE system is to achieve higher throughput, increased base station capacity. Also to reduce user and operators cost by improving coverage, data rates, and reducing latency. This paper makes review on LTE Architecture, communication channel structure in LTE, challenges for LTE. This review also gives an insight into QoS and frequency reuse concept in LTE, which is important for future crowd in mobile communication. The paper provides the valuable and concise information to the researchers in the area of 3GPP LTE and 4G.
Design of Low Power Dynamic Comparator using Reversible Logic

The Performance of circuits based in CMOS transistor logic is close to reaching its limit. A new efficient system or technology is needed to provide solutions to computing and integration issue. The proposed work addresses the above circumstance by implementing the reversible logic in dynamic comparator so that the number of transistors can be reduced. This logic can also be implemented in order to lower the power consumption and improve performance of circuit. The inputs and outputs of reversible logic gates can be uniquely retrievable from each other. The proposed reversible ripple carry adder is designed using L and M gates which requires only 18 transistors while the number of transistor implemented in CMOS implementation is 20. The critical path is made minimal so that the routing is reduced which makes the delays negligible. Reversible computing has its applications in computer security and transaction processing and also in those areas which require high energy efficiency, speed and performance.
Evaluation of user information satisfaction of the Composite Health Care System

This thesis describes the level of User Information Satisfaction with the Composite Health Care System (CHCS) . A short-form User Information Satisfaction questionnaire, developed by Baroudi and Orlikowski (1988) , was administered to CHCS users at the Naval Hospital, Charleston. Dividing the users into three work groups: Physicians, Administrative, and Ancillary personnel; statistically significant differences in satisfaction between groups were found. Overall, physicians were least satisfied and administrative personnel were the most satisfied of the groups . The respondents as a whole showed noticeable differences in satisfaction with factors that comprise User Information Satisfaction. The respondents were dissatisfied with the factor relating to software contractor's services. However, the users were very satisfied with the factor describing local Management Information Department services.
A Possible Mechanism for the Decrease in Serum Thyroxine Level by a 2,3,7,8-Tetrachlorodibenzo- p -dioxin-Like Polychlorinated Biphenyl Congener, 3,3 (cid:1) ,4,4 (cid:1) ,5-Pentachlorobiphenyl in Mice

: Serum total thyroxine (T 4 ) and free T 4 levels were markedly decreased 7 days after treatment with 3,3 (cid:1) ,4,4 (cid:1) ,5-pentachlorobiphe-nyl (CB126) (2.5 mg/kg i.p.) in 2,3,7,8-tetrachlorodibenzo- p -dioxin (TCDD)-sensitive C57BL/6 mice but not in TCDD-resistant DBA/2 mice. At the same time, the level and activity of hepatic T 4 -UDP-glucuronosyltransferase (T 4 -UGT) were significantly increased in C57BL/6 mice but not in DBA/2 mice. Furthermore, the amounts of biliary [ 125 I]T 4 and [ 125 I]T
development of Parkinson’s

Amyloid aggregates of the deubiquitinase OTUB1 are neurotoxic, suggesting that they contribute to the disease ABSTRACT Parkinson’s disease (PD) is a multifactorial malady and the second most common neurodegenerative disorder, characterized by loss of dopaminergic neurons in the midbrain. A hallmark of PD pathology is the formation of intracellular protein inclusions, termed Lewy bodies (LBs). Recent MS studies have shown that OTU deubiquitinase ubiquitin aldehyde binding 1 (OTUB1), a deubiquitinating enzyme of the OTU family, is enriched together with α -synuclein in LBs from individuals with PD and is also present in amyloid plaques associated with Alzheimer’s disease. In the present study, using mammalian cell cultures and a PD mouse model, along
A multi-scale filament extraction method: getfilaments

Far-infrared imaging surveys of Galactic star-forming regions with Herschel have shown that a substantial part of the cold interstellar medium appears as a fascinating web of omnipresent filamentary structures. This highly anisotropic ingredient of the interstellar material further complicates the difficult problem of the systematic detection and measurement of dense cores in the strongly variable but (relatively) isotropic backgrounds. Observational evidence that stars form in dense filaments creates severe problems for automated source extraction methods that must reliably distinguish sources not only from fluctuating backgrounds and noise, but also from the filamentary structures. A previous paper presented the multi-scale, multi-wavelength source extraction method getsources based on a fine spatial scale decomposition and filtering of irrelevant scales from images. In this paper, a multi-scale, multi-wavelength filament extraction method getfilaments is presented that solves this problem, substantially improving the robustness of source extraction with getsources in filamentary backgrounds. The main difference is that the filaments extracted by getfilaments are now subtracted by getsources from detection images during source extraction, greatly reducing the chances of contaminating catalogs with spurious sources. The intimate physical relationship between forming stars and filaments seen in Herschel observations demands that accurate filament extraction methods must remove the contribution of sources and that accurate source extraction methods must be able to remove underlying filamentary structures. Source extraction with getsources now provides researchers also with clean images of filaments, free of sources, noise, and isotropic backgrounds.
historical perspectives From Belfast to Mayo and beyond: the use and future of plethysmography to study blood ﬂow in human limbs

Joyner, Dietz, and T. Shepherd. From Belfast to Mayo and beyond: the use and future of plethysmography to study blood ﬂow in human limbs. J Appl Physiol 91: 2431–2441, 2001. —Venous occlusion plethysmography is a simple but elegant technique that has contributed to almost every major area of vascular biology in humans. The general principles of plethysmography were appreciated by the late 1800s, and the application of these principles to measure limb blood ﬂow occurred in the early 1900s. Plethysmography has been instrumental in studying the role of the autonomic nervous system in regulating limb blood ﬂow in humans and important in studying the vasodilator responses to exercise, reactive hyperemia, body heating, and mental stress. It has also been the technique of choice to study how human blood vessels respond to a variety of exogenously administered vasodilators and vasoconstrictors, especially those that act on various autonomic and adrenergic receptors. In recent years, plethysmography has been exploited to study the role of the vascular endothelium in health and disease. Venous occlusion plethysmography is likely to continue to play an important role as investigators seek to understand the physiological signiﬁcance of newly identiﬁed vasoactive factors and how genetic polymorphisms affect the cardiovascular system in humans.
of Using a Distended Abdomen to Predict in

Gangrene of the extremities is a well recognized, but an uncommon clinical condition affecting all ages and both sexes. Aetiological factors include infections' and hypematraemic dehydration. The underlying pathological mechanism is associated with intravascular coagulation. ' Five cases (three males and two females) were seen over a 30-month period in our hospital. Their ages ranged from 9 weeks to 13 years. Fever was the commonest presenting symptom. All the patients were well nourished except the 9-week-old infant; one was homozygous for the sickle cell gene. The blood coagulation studies in all patients were within the normal range. Blood culture in two patients grew N. meningitides, whilst each of the remaining three grew Escherichia coli, Klebiesiella and Salmonella typhii, respectively. Two of the patients died, two of the surviving three had amputation of the involved limbs. The histology of the amputated limb in one of the cases showed intra arterial thrombus formation. Skin and soft tissue necrosis in Neisseria meningitides infection have been attributed to a number of factors including vasculitis and intravascular thrombosis. Neisseria meningitides, a preventable infection was responsible for two of the five cases. The cost of rehabilitation of an amputee could be quite enormous especially in children who need regular revision of their prostheses during growth. Meningococcal vaccination is advocated especially in areas where epidemic occurs. Y. B. ADEWUMI, S. N. OKOLO, AND T. IGE* Jos University Teaching Hospital, Departments of Paediatrics and *Surgery, Jos, Plateau State, Nigeria
Texture classification with tree-structured wavelet transform

Proposes a multiresolution approach based on a tree-structured wavelet transform for texture classification. The development of tree-structured wavelet transform is motivated by the observation that textures are quasi-periodic signals whose dominant frequencies are located in the middle frequency channels. With the transform, one is able to zoom into desired frequency channels and performs further decomposition. In contrast, the conventional wavelet transform only decomposes subsignals in low frequency channels. A progressive texture classification algorithm which is not only computationally attractive but also has excellent performance is developed. <<ETX>>
human IL10 Human IL10 repression by Reverb alpha ameliorates Mycobacterium tuberculosis clearance*

Background: Transcriptional modulation of IL10 , cytokine that blocks phago-lysosome maturation. Results: human IL10 gene repression by direct binding of Reverbα on Rev-DR2 in the proximal promoter. Conclusion: Reverbα binds to IL10 proximal promoter, represses expression and impedes Mycobacterium tuberculosis in human macrophages. Significance: This study provides rationale to target Rev-erb as a therapeutic intervention that might support host defence in tuberculosis.