Miracle-dz/UniFAR-FTUs huggingface dataset:
Repeat cryoablation as a redo procedure for atrial fibrillation ablation: Is it a good choice?

BACKGROUND Ablation of atrial fibrillation (AF), both cryoablation ablation (CBA) and radiofrequency catheter ablation (RFCA), have demonstrated to be safe and effective. About 1 in 3 patients may face a redo due to recurrence and the best technique is unknown. The aim of this study is to assess the efficacy of CBA as a repeat procedure in patients with prior CBA or RFCA. METHODS A nation-wide CBA registry (RECABA) was analyzed and patients were compared who had previously undergone CBA (Prior-CB) or RFCA (Prior-RF). The primary endpoint was AF recurrence at 12 months after a 3-month blanking period. A survival analysis was performed, univariate and multivariate Cox models were also built. RESULTS Seventy-four patients were included. Thirty-three (44.6%) were in the Prior-CB group and 41 (55.4%) in the Prior-RF. There were more reconnected pulmonary veins in the Prior-RF than in Prior-CB group (40.4% vs.16.5%, p = 0.0001). The 12-month Kaplan-Meier estimate of freedom from AF recurrence after the blanking period was 61.0% (95% confidence interval [CI] 41.4-75.8%) in the Prior-CB, and 89.2% (95% CI 73.6-95.9%) in the Prior-RF group (p = 0.002). Multivariate Cox regression pointed Prior-CB as the sole independent predictor of AF recurrence, with an adjusted HR of 2.67 (95% CI 1.05-6.79). CONCLUSIONS Repeat CBA shows higher rates of AF recurrences compared to CBA after a previous RFCA despite presenting less reconnected veins at the procedure. These data suggest that patients with AF recurrence after CBA may benefit from other ablation techniques after a recurrence. RECABA is registered at clinicaltrials.gov with the Unique Identifier NCT02785991.
Managing Risk with Simulated Copula

The aim of this study is verify whether the Average Value at Risk (AVaR) can be a good alternative to Value at Risk (VaR), for estimating great portfolio losses, especially regarding tail events. To do so we use copula framework to estimate dependence between stock returns of a portfolio composed by 94 stock of the S&P100 in order to compute AVaR and VaR and compare the results with respect to a Gaussian Exponentially Weighted Moving Average (EWMA). For computing simulated returns, we use the algorithm presented in [Biglova et all, 2014] and then the model is back-tested with Kupiec's and Christoffersen's tests. The results are coherent with the literature and in particular VaR computed both via copula and EWMA seems to fail to provide an accurate risk measurement while AVaR under copula and EWMA looks more reliable.
NORMAL CLASSIFICATION OF 3D OCCUPANCY GRIDS FOR VOXEL-BASED INDOOR RECONSTRUCTION FROM POINT CLOUDS

Abstract. In this paper, we present an automated method for classification of binary voxel occupancy grids of discretized indoor mapping data such as point clouds or triangle meshes according to normal vector directions. Filled voxels get assigned normal class labels distinguishing between horizontal and vertical building structures. The horizontal building structures are further differentiated into those with normal directions pointing upwards or downwards with respect to the building interior. The derived normal grids can be deployed in the context of an existing voxel-based indoor reconstruction pipeline, which so far was only applicable to indoor mapping triangle meshes that already contain normal vectors consistently oriented with respect to the building interior. By means of quantitative evaluation against reference data, we demonstrate the performance of the proposed method and its applicability in the context of voxel-based indoor reconstruction from indoor mapping point clouds without normal vectors. The code of our implementation is made available to the public at https://github.com/huepat/voxir.
Personalized Approaches to Stroke: One Step Forward for Functional Recovery of Stroke Patients

Recent advances in diagnoses, management, and rehabilitation have had a significant impact to reduce mortality and functional recovery in stroke patients. In spite of these medical advances, many stroke survivors still suffer from significant disabilities. Stroke is a complex disease caused by a combination of multiple risk factors. Therefore, personalized medicine is more important than any other field to overcome the limitations of current stroke management and rehabilitation. It is necessary to apply accurate evaluation for functions and a personalized approach in consideration of various characteristics of each stroke patient to improve function. The objective of this Special Issue is to inform the recent scientific knowledge, current limitations, and challenges for an individually tailored strategy in the areas of diagnosis, treatment, and rehabilitation of stroke. A multidisciplinary approach and research will be strongly encouraged for personalized medicine in the field of stroke treatment and rehabilitation.
MTP8 from Triticum urartu Is Primarily Responsible for Manganese Tolerance

Mineral nutrients, such as manganese (Mn) and iron (Fe), play essential roles in many biological processes in plants but their over-enrichment is harmful for the metabolism. Metal tolerance proteins (MTPs) are involved in cellular Mn and Fe homeostasis. However, the transporter responsible for the transport of Mn in wheat is unknown. In our study, TuMTP8, a Mn-CDF transporter from diploid wheat (Triticum urartu), was identified. Expression of TuMTP8 in yeast strains of Δccc1 and Δsmf1 and Arabidopsis conferred tolerance to elevated Mn and Fe, but not to other metals (zinc, cobalt, copper, nickel, or cadmium). Compared with TuVIT1 (vacuole Fe transporter), TuMTP8 shows a significantly higher proportion in Mn transport and a smaller proportion in Fe transport. The transient analysis in tobacco epidermal cells revealed that TuMTP8 localizes to vacuolar membrane. The highest transcript levels of TuMTP8 were in the sheath of the oldest leaf and the awn, suggesting that TuMTP8 sequesters excess Mn into the vacuole in these organs, away from more sensitive tissues. These findings indicate that TuMTP8, a tonoplast-localized Mn/Fe transporter, functions as a primary balancer to regulate Mn distribution in T. urartu under elevated Mn conditions and participates in the intracellular transport and storage of excess Mn as a detoxification mechanism, thereby conferring Mn tolerance.
Tribodiagnostic investigation on oil filtration: results from a novel apparatus

Purpose The paper aims to deal with the analysis of tribodiagnostic parameters of oil filter device to investigate the possibility to launch a thorough treatment of non-invasive filtration of oil during the full operation of machinery and equipment. Design/methodology/approach Tribotechnical diagnostic of the oils is based on the observation of the operating oil aging and assesses the rate of change of intensity and the degree of degradation of the oil to change the performance characteristics of the oil and, thus, the capacity of oil for the satisfactory operation of the device. Tribotechnical diagnostic equipment is based on monitoring the wear of its components and assessing the concentration of wear particles in the analyzed oil and intensity of wear. Findings The monitored values show a stabilization at levels in which the contamination cannot damage machinery and equipment and their individual components. It is shown that with this method, the oil becomes a very important indicator and gives, by using several tribotechnical analysis described in the paper, immediate representation of the internal condition of the tribosystems in the machine. The desired level of purity of the oil system becomes a standard value for the next period of operation, and any deviation of analyzed values can be almost immediately identified. Originality/value The paper involves investigation on non-invasive filtration of oil during the full operation of machinery and equipment; non-invasive filtration experimental analysis of used oil after filtration; And experimental effectiveness evaluation of the filtration. Purity of the oil system becomes the target value for the online monitoring.
The Impact of Dynamic Games on the Coordination Development

This article aims to highlight the importance of dynamic games for the development of coordination abilities in children aged between 6 to 10 years. The research starts from the idea that the application of dynamic games in children training of the coordinative capacity at school age is more efficient than using conventional means of gymnastics and athletics. The experiment was conducted on two groups of children aged 6-7 years, the experimental group and the control group. As working methods were used bibliographic study method, experimental method, statistical and mathematical method. Results have been obtained after two tests, initial and final tests, the difference between these two tests was of 36 weeks.
Ion-Movement-Based Synaptic Device for Brain-Inspired Computing

As the amount of data has grown exponentially with the advent of artificial intelligence and the Internet of Things, computing systems with high energy efficiency, high scalability, and high processing speed are urgently required. Unlike traditional digital computing, which suffers from the von Neumann bottleneck, brain-inspired computing can provide efficient, parallel, and low-power computation based on analog changes in synaptic connections between neurons. Synapse nodes in brain-inspired computing have been typically implemented with dozens of silicon transistors, which is an energy-intensive and non-scalable approach. Ion-movement-based synaptic devices for brain-inspired computing have attracted increasing attention for mimicking the performance of the biological synapse in the human brain due to their low area and low energy costs. This paper discusses the recent development of ion-movement-based synaptic devices for hardware implementation of brain-inspired computing and their principles of operation. From the perspective of the device-level requirements for brain-inspired computing, we address the advantages, challenges, and future prospects associated with different types of ion-movement-based synaptic devices.
Tek bakış açısı derinlik kestirimi yöntemi ile robot denetimi

In this thesis formation control in a multi-robot system using single view depth estimation method and circling around a target for mobile robots by feedback linearization were studied. In order to sense objects in three dimension stereo vision is necessary. In other words, two eyes for humans and two cameras for robots are needed for three dimensional sensing. For measuring distance a feature of an object, which is height in this study, is known and this information is used to explain how to measure an object’s distance by single view depth estimation method that’s developed. Khepera 3 mini robots were used in the experiments and since they were not equipped with the necessary equipments like webcams, servo motors, etc. , these parts were chosen appropriately and integrated to the robots. A driver for chosen webcam was also compiled. OpenCV was used for image processing. Necessary OpenCV libraries were cross-compiled and added on robots via a flash disk. In these studies, which are done on 3 or 4 robots, it was observed that robots can successfully go to their destination points without breaking formation, using their designed controllers and a simple webcam mounted on them. In the study using a single robot using the feedback linearization techniques a controller for circling around a target with a predefined radius was implemented. This study constitutes a preliminary study towards a multi-agent system application in which robots constitutes targets to each other.
Collaborative Governance in Building Utilization Cultural Heritage in Metro City Through the Lens of a Socio-Legal Regime

The paradigm of the utilization of cultural heritage is aimed at the welfare of the community. Metro City of Lampung has buildings for cultural heritage from colonization era which are in need with optimum participation of various stakeholders to keep the cultural heritage existence to improve the welfare of the people. The artcle analysis the implementation of collaborative governance in the utilization of cultural heritage buildings in Metro City and ways to encourage strengthening collaboration within the framework of regional regulations in the utilization. Uses a socio-legal approach, it adresses the implementation of collaborative governance offered by Ansel and Gash (2007) with regards to conditions, institutional design, leadership, and collaborative process. Despite a local research in origin, the topic addressed in this article may have wider impact to national level in Indonesia. It is demonstrated that the use of collaborative governance through the concept of gotong-royong (mutual help) has proven to have an impact on the growth of various initiatives and public participation in the development of cultural heritage in Metro City. In addition, to strengthen collaborative governance, the presence of regional regulations related to The Preservation of Cultural Heritage is expected for the process of collaboration among stakeholders.
Wideband Microstrip to 3-D-Printed Air-Filled Waveguide Transition Using a Radiation Probe

In this letter, a novel wideband microstrip to additively fabricated waveguide transition is presented. The proposed design takes advantage of the flexibility of 3-D printing to realize a highly integrated transition from the microstrip line on a printed circuit board (PCB) to an air-filled waveguide using an additively manufactured radiating probe. The idea is experimentally verified by the realization of an exemplary transition working within the X-band at <inline-formula> <tex-math notation="LaTeX">$f_{0} =10.5$ </tex-math></inline-formula> GHz. The measured performance of the back-to-back transition proves its usefulness and possibility of utilization in highly integrated PCB-waveguide circuits. A PolyJet printing technology with copper electroplating was used in combination with PCB on microwave grade laminate. A bandwidth of <inline-formula> <tex-math notation="LaTeX">$f_{H}/f_{L} =1.8$ </tex-math></inline-formula> was obtained with the impedance match better than 9.5 dB and in-band insertion loss per transition below 1.1 dB.
Network Traffic Analysis Using Packet Sniffer-A Review

A B S T R A C T Network sniffer is a program and/or device that monitor data traveling over a network. Network sniffers can be used both for legitimate network management functions and for stealing information off a network. Network operations and maintenance personnel may use network sniffers to monitor network traffic, analyze packets, watch network resource utilization, conduct forensic analysis of network security breaches and troubleshoot network problems. Unauthorized network sniffers can be extremely dangerous to a network's security because they are virtually impossible to detect and can be inserted almost anywhere. This makes them a favorite weapon in the hacker's arsenal. Typical use of network sniffer is to analyze network traffic, so that underlying troubles in network can be found out. However, two directional usages of sniffer have coexisted since it was produced.
Lip filler with hyaluronic acid - Lip up technique

The lips and perioral region play an important role in facial aesthetics. Aging induces a loss of volume and contour of the lips, a flattening of the cupid's bow, and the appearance of perilabial wrinkles. Thus, aesthetic procedures are common in this area because fillers can reduce these alterations, improving facial harmony. Although the application of the fillers is based on some systematized framework, undesirable results could occur. The Lip Up technique is a method that applies a very small amount of small-particle hyaluronic acid, only 0.4 ml, to six specific points of the lips. The objective of the technique is to provide lifting of the labial commissures, highlighting some labial points, such as the Glogau-Klein points of the cupid's bow and its equivalent points on the lower lip. After the application of this technique, it is possible to observe an improvement of the lips with very natural-looking results.
Constructing Technology Commercialization Capability: The Critical Role of User Engagement and Big Data Analytics Capability

In the era of big data-driven digital economies, technology commercialization capability has become the lifeblood of high-tech enterprises to shape competitive advantage and achieve multiplier growth, while the related research is still limited. Drawing on the dynamic capability theory, this study asserts that external user engagement provides an imperative way to enhance technology commercialization capability. Although the highly complicated external environment may weaken this link, high-tech enterprises’ own big data analytics capability contributes to effectively coping with the unpredictable changing environment, thereby amplifying the brighter side of user engagement. The moderated moderation model and hypotheses were supported by the unique surveys of 216 high-tech enterprises. Further, the findings broaden the vision of related research fields, and provide meaningful practical guidance for strategic decision-making and dynamic capability constructing of high-tech enterprises in the new era.
Approximate Spring Balancing of Linkages to Reduce

The potential benet of applying gravity balancing to orthotic, prosthetic and other wearable devices is well recognized, but practical applications have been elusive. Although existing methods provide exact gravity balance, they require additional masses or auxiliary links, or all the springs used originate from the ground, which makes the resulting device bulky and space-inecient. This work presents a new method that is more practical than existing methods to provide approximate gravity balancing of mechanisms to reduce actuator loads. Current balancing methods use zero-free-length springs or simulate them to achieve balancing. Here, non-zero-free-length springs can be used directly. This new method allows springs to be attached to the preceding parent link, which makes the implementation of spring balancing practical. The method is applicable to planar and spatial, open and closed kinematic chains. Applications of this method to a lower-limb orthosis and a manually-operated sit-to-stand wheelchair mechanism are presented. Results show considerable reduction in actuator requirements with practical spring design and arrangements.
Wind Field Characteristics of Complex Terrain Based on Experimental and Numerical Investigation

With the intensification of energy consumption, how to make rational and efficient use of wind energy has been studied all over the world. The construction of facilities to obtain wind energy requires an accurate assessment of the wind characteristics of the local terrain. In order to study the wind characteristics on an island in Southeast China, a 1:1300 terrain model is established, and the characteristics of mean wind and fluctuating wind are studied by numerical simulation and wind tunnel test. The results show that wind speed is affected by the incoming wind direction and local terrain. Wind speed on windward slopes and flat areas with no obstructions is higher, and wind speed on leeward slopes and valleys is lower. Then, the wind attack angle of each measuring point is mainly in the range of −10°~10°, which is much higher than that in flat areas. The positive and negative wind attack angles are controlled by the incoming wind direction, and the size is closely related to the local terrain. As for pulsation characteristics, the disturbance of the inflow determines the turbulence intensity. The incoming wind direction mainly affects the turbulence intensity on the hillside, while the turbulence intensity in the valley and flat area is controlled by the local terrain. In addition, the fluctuating wind speed power spectra on the island is more consistent with the von Karman spectrum, which is quite different from the Kaimal spectrum. The bandwidth on hillsides and valleys will not change with the change in inflow, but for flat areas, the bandwidth is greatly affected by the inflow direction.
Effects of Etanercept on TNF-α Inhibition in Rats with Adenine-Induced Chronic Kidney Disease

Introduction Chronic kidney disease (CKD) constitutes a chronic inflammatory state associated with an increase in inflammatory mediators and profibrotic molecules such as tumor necrosis factor-α (TNF-α). Etanercept (ETA) is a TNF inhibitor widely used in treatment of autoimmune inflammatory diseases. However, the effects of TNF-α inhibition in the establishment of CKD have not been fully elucidated. We evaluate the effects of TNF inhibition by ETA in adenine- (Ad-) induced CKD in rats. Methods Rats were divided into three groups: control, renal injury model, and model plus ETA (2 mg/kg, 3 times per week (w); sc). Renal injury was induced by Ad administration (100 mg/kg, daily for 2 or 4 w; orogastric). Serum TNF-α levels and biochemical parameters for renal function were evaluated. Histopathological changes in the kidney were assessed using H&E and Masson's trichrome staining and also immunostaining for tubular cells. Results Ad administration produced a renal functional decline, tubular atrophy, interstitial inflammation, and fibrosis for 2 w, followed by renal anemia, several renal dysfunctions, tubular atrophy, and fibrosis at 4 w. A significant increase in serum TNF-α levels was observed from 2 w of Ad administration and remained elevated up to 4 w. Treatment with ETA partially reduced kidney damage but was very effective to blocking serum TNF-α. Conclusion Although inhibition of TNF by ETA was very effective in reducing serum TNF-α, this strategy was partially effective in preventing Ad-induced CKD.
Strategic formulation to increase white tea competitiveness (Case study: Research Institute for Tea and Cinchona)

White tea is a new product in Indonesiaâ€™s tea industry. It is a product developed by Research Institute for Tea and Cinchona in order to revive Indonesiaâ€™s tea industry. White tea has uniqueness in its relatively high price and high market demand that not affected by its high price. The increasing number from Indonesiaâ€™s middle class income could also become white teaâ€™s new potential consumer because they put quality and health first than the price. White teaâ€™s high price and demand attract new players in this industry. The appearence of new competitors make this in-dustry more competitive. Thatâ€™s why itâ€™s necce-sary to find a way to win the compettion and to keep the domination in the white tea industry through strategic formulation. There were two steps in strategic formulation used to produce the strategies. The first is analyzing the com-pany environment using internal factor evalua-tion (IFE) and external factor evaluation (EFE). The second is using internal and exter-nal (IE) matrix and strength weakness oppor-tunity and threat (SWOT) analysis. IE matrix showed the position of company using infor-mation from IFE and EFE. SWOT analysis resulted strategies using information from the companyâ€™s strength, weakness, opportunity, and threat. IFE and EFE showed that the company has strong internal power and good respond to external factors. IE matrix showed that com-pany is in grow and build stage. IE matrix and SWOT analysis showed that the alternative strategies for the company are market pene-tration, market development, product develop-ment, forward integration, backward integ-ration, and side integration.