Miracle-dz/UniFAR-FTUs huggingface dataset:
Analysis of Private Investors Conduct Strategies by Governments Supervising Public-Private Partnership Projects in the New Media Era

Private investors and governments need to cooperate in public–private partnership (PPP) projects but the private investors may be in pursuit of their own profit by conducting defaulting behaviors which causes various environmental problems and economic risks. However, the information asymmetry between them makes it difficult to supervise the behaviors of private investors. The development of internet and social media creates new environment for the information spread and people are using new media increasingly in the current society, providing an inexpensive and viable way for the public to participate in PPP projects. We constructed a dynamic evolutionary model to analyze the behaviors strategies of governments and private investors in the new media era and then analyzed how important factors influence the behavior trends of governments and private investors. These findings could provide meaningful insight to improve supervision status by using the new media environment and predict the behaviors of governments and private investors in PPP projects, which would be conductive for the governments to supervise the private investors in PPP projects more efficiently.
Normalteiler ganzzahliger Spingruppen.

Sei K ein algebraischer Zahlkörper, S eine endliche Menge von Stellen in K, darunter alle archimedischen, I der Ring derjenigen Zahlen aus K, die außerhalb S ganz sind, Gc:GLn eine A^-algebraische Matrizengruppe. Eine Untergruppe N von G (K) heißt ^-arithmetisch, wenn N n G(I) in 7V und in G(I) endlichen Index hat; sie heißt S-Kongruenzgruppe, wenn sie außerdem für ein gewisses I-Ideal q {0} alle Matrizen aus G(I) enthält, die modulo q zur Einheitsmatrix kongruent sind. Diese Definitionen sind von der speziellen Einbettung G c GLn unabhängig. Das Kongruenzgruppenproblem besteht darin, zu entscheiden ob jede 5-arithmetische Gruppe in G (K) eine S-Kongruenzgruppe ist. Bei halbeinfachen Gruppen hat es höchstens dann eine positive Antwort, wenn G einfach zusammenhängend ist [16]. Einen vollständigen Überblick hat man bei einfach zusammenhängenden zerfallenden (Chevalley-)Gruppen ([1], [9], [10] für Gruppen vom Rang 2>2, [17] für SL2). Teilergebnisse für ^-isotrope aber nicht zerfallende Gruppen enthalten die Arbeiten [14] und [20].
Value-Added Utilization of Citrus Peels in Improving Functional Properties and Probiotic Viability of Acidophilus-bifidus-thermophilus (ABT)-Type Synbiotic Yoghurt during Cold Storage

Citrus peel, a fruit-processing waste, is a substantial source of naturally occurring health-promoting compounds, including polyphenols, and has great potential as a dietary supplement for enhancing the functional properties of food. The present work aimed to investigate the effects of sour orange (SO), sweet orange (SWO), and lemon (LO) peels on the typical physiochemical, antioxidant, antibacterial, and probiotic properties of synbiotic yoghurt fermented by acidophilus-bifidus-thermophilus (ABT)-type cultures during cold storage (0–28 days). High-performance liquid chromatography-diode array detection (HPLC-DAD) analysis showed that the total phenolic content in the SO peel were more than 2-fold higher than that in the SWO and LO peel. The predominant phenolic compounds were myricetin (2.10 mg/g dry weight) and o-coumaric acid (1.13 mg/g) in SO peel, benzoic acid (0.81 mg/g) and naringin (0.72 mg/g) in SWO peel, and benzoic acid (0.76 mg/g) and quercetin (0.36 mg/g) in LO peel. Only 0.5% (w/w) of citrus peel addition did not reduce the overall acceptance of ABT synbiotic yoghurt but led to increased acidity and decreased moisture during cold storage (14 and 28 days). Additionally, compared to control samples without citrus peel addition, supplementation with citrus peels improved the antioxidant property of the ABT synbiotic yoghurt. ABT milks with SO and SWO peel addition had significantly stronger DPPH radical scavenging activities than that with LO peel addition (p < 0.05). Antibacterial analysis of ABT synbiotic yoghurt with citrus peel addition showed that the diameters of inhibition zones against S. aureus, B. subtilis, and E. coli increased by 0.6–1.9 mm relative to the control groups, suggesting the enhancement of antibacterial activities by citrus peels. The viabilities of probiotic starter cultures (L. acidophilus, S. thermophilus, and Bifidobacterial sp.) were also enhanced by the incorporation of citrus peels in synbiotic yoghurt during cold storage. Hence, our results suggest that citrus peels, especially SO and SWO peels, could be recommended as a promising multifunctional additive for the development of probiotic and synbiotic yoghurt with enhanced antioxidant and antibacterial properties, as well as probiotic viability.
Novel and Promising Strategies for Therapy of Post-Transplant Chronic GVHD

Despite the achievements that have increased viability after the transplantation of allogeneic hematopoietic stem cells (aHSCT), chronic graft-versus-host disease (cGVHD) remains the main cause of late complications and post-transplant deaths. At the moment, therapy alternatives demonstrate limited effectiveness in steroid-refractory illness; in addition, we have no reliable data on the mechanism of this condition. The lack of drugs of choice for the treatment of GVHD underscores the significance of the design of new therapies. Improved understanding of the mechanism of chronic GVHD has secured new therapy goals, and organized diagnostic recommendations and the development of medical tests have ensured a general language and routes for studies in this field. These factors, combined with the rapid development of pharmacology, have helped speed up the search of medicines and medical studies regarding chronic GVHD. At present, we can hope for success in curing this formidable complication. This review summarizes the latest clinical developments in new treatments for chronic GVHD.
Prevalencia de Dientamoeba fragilis y otros protozoarios intestinales en porcinos de una granja en la región Andina de Colombia

Dientamoeba fragilis es un protozoario que parasita el intestino grueso del hombre y animales domésticos. Hasta el momento, aún no son claros aspectos de su ciclo de vida, como el rango de hospedadores, reservorios, mecanismo de infección, entre otros. Se postula que el cerdo es un hospedador natural para este protozoario y que, debido a su cercanía con el humano, podría facilitar una transmisión zoonótica. En Colombia no existen a la fecha estudios sobre la presencia de D. fragilis en hospedadores animales, incluidos los cerdos, y los datos sobre la prevalencia de otros protozoarios intestinales en estos animales son escasos. El objetivo fue determinar la frecuencia de protozoarios intestinales, incluyendo D. fragilis, en cerdos de una granja tecnificada de una zona rural de Medellín (región Andina de Colombia). Se recolectaron muestras de materia fecal de 70 cerdos en etapa de preceba, que fueron evaluadas mediante examen directo, tinción tricrómica y Ziehl-Neelsen modificado. Se realizaron análisis univariados con medidas de frecuencia relativa y tendencia central y análisis bivariados para la exploración de factores de riesgo. Se detectó la presencia de D. fragilis en un 13% de las muestras y de otros parásitos como Entamoeba spp. (66%), Blastocystis spp. (64%), Balantioides coli (36%), Cryptosporidium spp. (36%), Iodamoeba butschlii (17%), coccidias (4%) y Giardia spp. (1,4%). En este primer reporte de D. fragilis en cerdos en Colombia se observó la alta prevalencia de otros protozoarios patógenos, lo que corrobora el papel de los cerdos como importantes reservorios de infecciones humanas.
Sustainability of Micro Business Actors during the COVID-19 Pandemic

This study aims to investigate the effect of leadership, business motivation, and compensation during the Covid-19 pandemic on business existence. This study was conducted in a traditional market in Lubuklinggau City, South Sumatra, Indonesia, with a population of 120 respondents from 1200 micro-enterprises. The validity and reliability tests of 36 samples were conducted using SPSS statistics and inferential analysis using the Amos 8.8 Structural Equation Model (SEM). It was found that leadership has a significant effect on business existence by 0.83, compensation has an effect on business existence by 0.17, and business motivation also affects business existence by 0.24. An important finding from this study is that these three variables together affect the existence of businesses during the Covid-19 pandemic. However, the leadership factor of microbusiness actors is more dominant in influencing the business's existence. Implementing awareness-based health protocols will also have a positive impact on tackling the Covid-19 pandemic. In addition, entrepreneurs can also continue to run their businesses and can foster economic stability, especially in traditional markets. Doi: 10.28991/esj-2022-SPER-020 Full Text: PDF
Desirable attributes of theories, models, and frameworks for implementation strategy design in healthcare: a scoping review protocol

Background: Implementation strategies can facilitate the adoption of evidence-based practices and policies. A wide range of theoretical approaches—theories, models, and frameworks—can be used to inform implementation strategy design in different ways (e.g., guiding barrier and enabler assessment to implementing evidence-based interventions). While selection criteria and attributes of theoretical approaches for use in implementation strategy design have been studied, they have never been synthesized. Furthermore, theoretical approaches have never been classified according to desirable criteria and attributes for use in implementation strategy design. This scoping review aims to a) identify the literature reporting on the selection of theoretical approaches for informing implementation strategy design in healthcare and b) understand the suggested use of these approaches in implementation strategy design. Methods: The Joanna Briggs Institute methodological guidelines will be used to conduct this scoping review. A search of three bibliographical databases (MEDLINE, Embase, CINAHL) will be conducted for peer-reviewed discussion, methods, protocol, or review papers. Data will be managed using the Covidence software. Two review team members will independently perform screening, full text review and data extraction. Results: Results will include a list of selection criteria and attributes of theoretical approaches for use in research on implementation strategy design. Descriptive data regarding selection criteria and attributes will be synthesized graphically and in table format. Data regarding the suggested use of theoretical approaches in implementation strategy design will be presented narratively. Conclusions: Results will be used to classify existing theoretical approaches according to the attributes and selection criteria identified in this scoping review. Envisioned next steps include an online tool that will be created to assist researchers in selecting theories, models, and frameworks for implementation strategy design.
Planning and scheduling in healthcare for better care coordination: Current understanding, trending topics, and future opportunities

This study reviews the research on planning and scheduling in healthcare published in Production and Operations Management (POM) and other prestigious operations management journals over the past 30 years, identifies trending topics, and discusses opportunities for future research. Specifically, we categorize the capacity planning literature into three problem contexts: (a) hospital units and operating rooms, (b) outpatient clinics, and (c) broader healthcare networks. We further classify the scheduling literature into (a) appointment scheduling, (b) surgery and workforce scheduling, and (c) recurring and integrated scheduling, with several subtopics that have attracted attention in the literature. Afterward, we demonstrate the seven emerging trends in healthcare (i.e., collaborative ecosystem and cooperative competition strategy, expanded reach of virtual care, applications of artificial intelligence in healthcare, patient engagement and personalized care, shifting to value‐based care, working toward health equity, and aging populations) and list relevant research opportunities and their related departments of POM journal. We conclude with a call for multidisciplinary perspectives to deliver coherent solutions that incorporate the complex contemporary issues harmoniously.
Current Progress of CAR-NK Therapy in Cancer Treatment

Simple Summary Chimeric antigen receptor (CAR)-T and -natural killer (NK) therapies are promising in cancer treatment. CAR-NK therapy gains great attention due to the lack of adverse effects observed in CAR-T therapies and to the NK cells’ unique mechanisms of recognizing target cells. Off-the-shelf products are in urgent need, not only for good yields, but also for lower cost and shorter preparation time. The current progress of CAR-NK therapy is discussed. Abstract CD8+ T cells and natural killer (NK) cells eliminate target cells through the release of lytic granules and Fas ligand (FasL)-induced target cell apoptosis. The introduction of chimeric antigen receptor (CAR) makes these two types of cells selective and effective in killing cancer cells. The success of CAR-T therapy in the treatment of acute lymphoblastic leukemia (ALL) and other types of blood cancers proved that the immunotherapy is an effective approach in fighting against cancers, yet adverse effects, such as graft versus host disease (GvHD) and cytokine release syndrome (CRS), cannot be ignored for the CAR-T therapy. CAR-NK therapy, then, has its advantage in lacking these adverse effects and works as effective as CAR-T in terms of killing. Despite these, NK cells are known to be hard to transduce, expand in vitro, and sustain shorter in vivo comparing to infiltrated T cells. Moreover, CAR-NK therapy faces challenges as CAR-T therapy does, e.g., the time, the cost, and the potential biohazard due to the use of animal-derived products. Thus, enormous efforts are needed to develop safe, effective, and large-scalable protocols for obtaining CAR-NK cells. Here, we reviewed current progress of CAR-NK therapy, including its biological properties, CAR compositions, preparation of CAR-NK cells, and clinical progresses. We also discussed safety issues raised from genetic engineering. We hope this review is instructive to the research community and a broad range of readers.
Nursing and Midwifery Students’ Mental Health Status and Intention to Leave During Covid-19 Pandemic

Introduction COVID-19 has not only affected the physical health of people but it has also had a major impact on their mental health. Objective To investigate the nursing, midwifery, and operating room students’ mental health and intention to leave during COVID-19 pandemic. Methods This cross-sectional study was conducted at the nursing and midwifery school of Tabriz, Iran. Over a period of three months (February–May 2021) and through random sampling, 284 students were selected. The research tool consisted of three parts including demographic information, Depression Anxiety Stress scales, and a questionnaire on intention to leave. Results More than 20% of the students experienced some degrees of depression, anxiety, and stress. Nearly one-third of participants mentioned a high level of intention to leave. Nursing students had a higher level of a turnover tendency than other students (p = .004). Male students and who experienced moderate to high level of depression displayed greater intention to leave (p = .005). Conclusion Students suffered from some degrees of stress, anxiety, and depression during the COVID-19, and it strengthened the participants’ intention to leave. Relevant authorities are recommended to improve mental health of the students by providing psychological counseling sessions, reducing their direct contact with patients, and providing personal protective equipment.
Gastric Emptying of Maltodextrin versus Phytoglycogen Carbohydrate Solutions in Healthy Volunteers: A Quasi-Experimental Study

Preoperative carbohydrate beverages have been shown to be beneficial in improving patient outcomes. There have been several investigations into the safety of maltodextrin as a preoperative carbohydrate. Although alternative preoperative carbohydrate sources have been proposed, there have been few investigations into the safety and gastric emptying of novel carbohydrate beverages. The present study aimed to compare the gastric emptying of phytoglycogen and maltodextrin to evaluate safety for use as presurgical carbohydrate beverages. In a quasi-experimental design, ten healthy participants orally consumed either a 12.5% maltodextrin or a 12.5% phytoglycogen solution. Gamma scintigraphy was used to evaluate gastric emptying at baseline at 45, 90, and 120 min. Serum insulin and serum glucose were measured at baseline at 15, 30, 45, 60, 90, and 120 min. Gastric volume was significantly lower in the phytoglycogen group at 45 min (p = 0.01) and 90 min (p = 0.01), but this difference lost significance at 120 min (p = 0.17). There were no significant differences between treatments for serum insulin or serum glucose at any time point. This study indicates that the gastric emptying of phytoglycogen is comparable to maltodextrin at 120 min after ingestion, opening the opportunity for the study of alternative carbohydrates for utilization as preoperative carbohydrates.
Consumption and Hours in the United States and Europe

: We document large differences between the United States and Europe in allocations of expenditures and time for both market and home activities. Using a life-cycle model with home production and endogenous retirement, we find that the cross-country differences in consumption tax, social security system, income tax, and total factor productivity (TFP) together can account for from 68 to 95 percent of the cross-country variations in aggregate hours and expenditures. These factors can also account well for the cross-country differences in allocations by age and generate substantially lower market hours in Europe for the age group of 60 and above as in the data. All the factors, except income tax, are quantitatively important for determining cross-country differences in expenditure allocations. Although the differences in social security system and income tax are crucial in explaining the difference in market hours around retirement ages, TFP and consumption tax are more important for the difference in market hours for prime ages.
Seasonality, body size, and maturation time in the neotropical grasshopper Sphenarium histrio across an altitudinal gradient

In insects, male mating success and female fecundity usually increase with body size. However, natural selection favors faster maturation, reducing the risk of pre‐reproductive death, when the reproductive season is short in habitats located at high altitudes or far from the equator. Also, if males that mature earlier than females under these conditions increase their mating opportunities, protandry may evolve in their populations. Nonetheless, as body size is strongly correlated with maturation time in insects, faster sexual maturation is reached at the expense of having a small body size. We analyzed the differences in adult body size of males and females of the grasshopper Sphenarium histrio Gerstaecker (Orthoptera: Pyrgomorphidae) in three sites across an altitudinal gradient in southern Mexico. We also evaluated the possibility of protandry in these sampling sites using a common garden experiment. Male and female grasshoppers collected from low altitude sites in the field and reared in the laboratory were larger than those from a high altitude, suggesting genetic differentiation. Grasshoppers from a high altitude hatched earlier, had a shorter development time, presented fewer instars, and were smaller than grasshoppers from the other sampling sites. Moreover, development time in the three sampling sites was shorter in males than in females, suggesting protandry. Interestingly, the males from the three sites showed similar growth rates, but the females from low and high altitudes, respectively, had the fastest and slowest growth rates. In general, the adaptive value of the evolution of protandry has been focused on males. However, it may be that the growth rates of females in these sites could modify the degree of protandry as a response to their risk of pre‐reproductive death and the potential benefits associated with multiple matings.
The AGN Ionization Cones of NGC 5728. I. Excitation and Nuclear Structure

We explore the gas morphology and excitation mechanisms of the ionization cones of the Type II Seyfert galaxy NGC 5728. Near-IR and optical data from the SINFONI and MUSE integral field units on the Very Large Telescope are combined with Hubble Space Telescope optical images, Chandra X-ray data, and Very Large Array radio observations. The complex nuclear structure has a star-forming (SF) ring with a diameter of 2 kpc. A radio jet impacts on the interstellar medium at about 200 pc from the nucleus, with the supernova remnants in the SF ring also present. Emission-line ratios of [Fe ii] and H ii show heavy extinction toward the nucleus, moderate extinction in the SF ring, and reduced extinction in the ionization cones. The active galactic nucleus (AGN) is hidden by a dust bar with up to 19 mag of visual extinction; the dust temperature at the nuclear position is ∼870 K. An X-ray jet is aligned with the ionization cones and associated with high-excitation emission lines of [Si vi] in a coronal line region extending 300 pc from the nucleus. Molecular hydrogen is spatially independent of the cones, concentrated in a disk equatorial to the SF ring, but also showing entrainment along the sides of the bicone. Gas masses for warm and cold H2, H i, and H ii are estimated, and the excitation mechanisms for ionized and molecular gas are elucidated, from both optical (which shows a clean SF–AGN mixing sequence) and infrared diagnostics (which show more complicated, multicomponent excitation regimes).
Dietary Supplements Use among Serbian Undergraduate Students of Different Academic Fields

The rising popularity of dietary supplements as a part of self-care practice increases interest in monitoring their usage in the general and specific population groups. This study investigated the prevalence and patterns of dietary supplement use among Belgrade University undergraduate students and its variations across different academic study fields. Of the 914 online survey students, 55.7% used dietary supplements during the past year. Female gender, eating behavior, and academic field were significant predictors of dietary supplement use. For all students, the most commonly used dietary supplements were vitamins and minerals, alone or in combination. Magnesium, vitamin C, and B vitamins were the most frequently supplemented micronutrients. The reasons for using, place of purchase, and source of information regarding dietary supplements significantly varied among students of different fields of study. Adverse effects related to dietary supplement use, including gastrointestinal symptoms, skin flushing, dizziness, and heart palpitation, were reported in 4.5% of students. Insufficient knowledge about these products was self-reported by 16.5% of users, more common among non-medical students. Thus, public health interventions are needed to improve students’ knowledge regarding rational and safe dietary supplement use.