Miracle-dz/UniFAR-FTUs huggingface dataset:
Contemporaneous causality among residential housing prices of ten major Chinese cities

Purpose This study aims to investigate dynamic relationships among residential housing price indices of ten major Chinese cities for the years 2005–2021. Design/methodology/approach Using monthly data, this study uses vector error correction modeling and the directed acyclic graph for characterization of contemporaneous causality among the ten indices. Findings The PC algorithm identifies the causal pattern and the Linear Non-Gaussian Acyclic Model algorithm further determines the causal path, from which this study conducts innovation accounting analysis. Sophisticated price dynamics are found in price adjustment processes following price shocks, which are generally dominated by the top tiers of cities. Originality/value This study suggests that policies on residential housing prices in the long run might need to be planned with particular attention paid to these top tiers of cities.
Pengaruh Penerapan Dan Kemudahan Penggunaan E-SPT Terhadap Efisiensi Pemrosesan Data Perpajakan Dengan Pemahaman Internet Sebagai Variabel Moderasi

Tujuan dari penelitian ini adalah untuk mengetahui pengaruh dari penerapan dan kemudahan e-SPTterhadap efisiensi pemrosesan data perpajakan dengan dimoderasi oleh pemahaman internet. Populasi dalampenelitian ini adalah 186.034 WPOP yang terdaftar di KPP Pratama Ilir Timur Palembang. Teknik pengambilansampel menggunakan incidental sampling, dengan penentuan jumlah sampel menggunakan rumus slovin sebanyak100 WPOP. Jenis data menggunakan data primer. Teknik pengumpulan data menggunakan kuesioner. Teknikanalisis data menggunakan uji validitas, uji reliabilitas, uji asumsi klasik, Uji R 2 , uji F, uji T, uji Causal Step, dan ujiModerated regression analysis (MRA) dengan bantuan SPSS versi 23. Hasil penelitian menunjukkan penerapan e-SPT dan kemudahan penggunaan e-SPT berpengaruh terhadap efisiensi pemrosesan data perpajakan. Pemahamaninternet tidak mampu memoderasi hubungan antara penerapan e-SPT dan kemudahan penggunaan e-SPT terhadapefisiensi pemrosesan data perpajakan
Eurozone Crisis, Policy Actions and Financial Market Volatility

—After the outbreak of the Eurozone crisis, the overall stability of the euro area was undermined. European countries have adopted different policy actions. We analyzed the reaction of German, Spanish and Irish stock market indices to announcements of policy action between January 1, 2000 and December 31, 2016. Past papers have analyzed the impact of policy actions on financial markets and the economy of Europe as a whole. Our paper focuses on stock indices and establishes the relationship between stock indices and policy actions through the generalized autoregressive conditional heteroskedasticity (GARCH) model. Through the analysis of the model test results, we find that the policies issued after the eurozone crisis have no significant impact on the volatility of financial markets.
Sentiment Analysis of Italian and English Corpora of Internet News: A Comparison with Some Economic Trends

In this article, the sentiment analysis of several large Internet corpora made of Italian and English news is performed using a software written by the author, showing a possible connection with some economic trends. In this research, the news includes different topics (not necessarily financial news), and they are extrapolated from a large number of Internet newspapers. The software, already used in a previous article by the same author, is lexicon-based and makes use of scale points ranging from 0 to 100 to calculate an index of positivity in a text. The variation of sentiment tendency in the news corpora, calculated for a time period of several years, is later compared with some graphs showing some parameters of some economic trends, including the gross domestic product (GDP). It is found that the sentiment tendency of the news seems to have a relationship with the tendency of some economic trends that span the same time period. Positive growth of the economy per year seems connected with a positive variation in the index of positivity. Inversely, for a negative trend in the economy, the variation in the index of positivity is also negative. The article shows that, for various news topics, sentiment analysis can be useful to better understand some economic trends. For financial news, many studies show the possibility of predicting GDP growth through sentiment analysis. In this article, it is hypothesized that a prediction based on large news corpora including various topics could also be possible.
Comparing the Impact of Social Media Regulations on News Consumption

Users online tend to consume information adhering to their system of beliefs and ignore dissenting information. During the COVID-19 pandemic, users get exposed to a massive amount of information about a new topic having a high level of uncertainty. In this article, we analyze two social media that enforced opposite moderation methods, Twitter and Gab, to assess the interplay between news consumption and content regulation concerning COVID-19. We compare the two platforms on about three million pieces of content, analyzing user interaction with respect to news articles. We first describe users’ consumption patterns on the two platforms focusing on the political leaning of news outlets. Finally, we characterize the echo chamber effect by modeling the dynamics of users’ interaction networks. Our results show that the presence of moderation pursued by Twitter produces a significant reduction of questionable content, with a consequent affiliation toward reliable sources in terms of engagement and comments. Conversely, the lack of clear regulation on Gab results in the tendency of the user to engage with both types of content, showing a slight preference for the questionable ones which may account for a dissing/endorsement behavior. Twitter users show segregation toward reliable content with a uniform narrative. Gab, instead, offers a more heterogeneous structure where users, independent of their leaning, follow people who are slightly polarized toward questionable news.
On the Role of Dietary Nitrate in the Maintenance of Systemic and Oral Health

The assessment of the significance of nitrates ingested with food has undergone a fundamental change in recent years after many controversial discussions. While for a long time, a diet as low in nitrates as possible was advocated on the basis of epidemiological data suggesting a cancer-promoting effect of nitrate-rich diets, more recent findings show that dietary nitrate, after its conversion to nitrite by nitrate-reducing bacteria of the oral microbiota, is an indispensable alternative source for the formation of nitric oxide (NO), which comprises a key element in the physiology of a variety of central body functions such as blood pressure control, defense against invading bacteria and maintenance of a eubiotic microbiota in the gut and oral cavity. This compact narrative review aims to present the evidence supported by clinical and in vitro studies on the ambivalent nature of dietary nitrates for general and oral health and to explain how the targeted adjuvant use of nitrate-rich diets could open new opportunities for a more cause-related control of caries and periodontal disease.
Diferencias de género en la maratón de Sevilla: ¿Presentan los hombres más exceso de confianza que las mujeres?

Previous studies show that people tend to overestimate their abilities and that men tend to be more overconfident than women. This study aims to analyse whether Spanish male runners overestimate their abilities compared to women. For this, runners’ predictions of their own finish times in the marathon of Seville 209 are used. Overconfidence is measured as the selection of a starting box made by each runner, based on the time they expect to get in the race, which is inferior to the actual time they are going to get. The results indicated that long-distance runners often give biased predictions and that the bias to be optimistic about the time they are going to get is greater in men than in women. The extent of this behaviour to other contexts may help to explain why women tend to be underrepresented in certain education or the gender wage gap and labour market segregation. Estudios previos muestran que la población tiende a sobreestimar sus habilidades y que los hombres tienden a presentar más exceso de confianza que las mujeres. Este estudio tiene como objetivo analizar si los corredores españoles hombres sobreestiman sus capacidades en comparación a las mujeres. Para ello, se utilizan las predicciones de los tiempos de los propios corredores en la maratón de Sevilla 2019. El exceso de confianza se mide como la autoselección en un cajón de salida con un tiempo esperado inferior al tiempo real conseguido. Los resultados muestran que los corredores de larga distancia con frecuencia dan predicciones sesgadas y que el sesgo a ser optimista en el tiempo es mayor en los hombres que en las mujeres. La extensión de este comportamiento a otros contextos puede ayudar a explicar por qué las mujeres tienden a estar infrarrepresentadas en ciertos estudios o la brecha salarial y la segregación en el mercado laboral.
The effect of academic mobility on research performance: The case of Italy

Abstract This work investigates the effects of researchers’ mobility on their research performance. The reference context is that of national intrasector mobility, in a country, Italy, characterized by a research system lacking the typical elements of an academic labor market. In particular, the analysis was conducted on 568 academics working at national universities and affected by mobility in the period 2009–2014. The effect of mobility on the variation of performance at the turn of the transfer was analyzed considering the interplay of demographic/sociological characteristics of the researchers, as well as contextual factors related to both the organization of origin and destination. Results show that it is the less productive academics who represent the larger share of those who move, and more than half of the mobile academics worsen their performance after the transfer.
Development of Ultrapure and Potent Tannic Acids as a Pan-coronal Antiviral Therapeutic

The rampageous transmission of SARS-CoV-2 has been devastatingly impacting human life and public health since late 2019. The waves of pandemic events caused by distinct coronaviruses at present and over the past decades have prompted the need to develop broad-spectrum antiviral drugs against them. In this study, our Pentarlandir ultrapure and potent tannic acids (UPPTA) showed activities against two coronaviral strains, SARS-CoV-2 and HCoV-OC43, the earliest-known coronaviruses. The mode of inhibition of Pentarlandir UPPTA is likely to act on 3-chymotrypsin-like protease (3CLpro) to prevent viral replication, as supported by results of biochemical analysis, a 3CLpro assay, and a “gain-of-function” 3CLpro overexpressed cell-based method. Even in the 3CLpro overexpressed environment, Pentarlandir UPPTA remained its antiviral characteristic. Utilizing cell-based virucidal and cytotoxicity assays, the 50% effective concentrations (EC50) and 50% cytotoxicity concentration (CC50) of Pentarlandir UPPTA were determined to be ∼0.5 and 52.5 μM against SARS-CoV-2, while they were 1.3 and 205.9 μM against HCoV-OC43, respectively. In the pharmacokinetic studies, Pentarlandir UPPTA was distributable at a high level to the lung tissue with no accumulation in the body, although the distribution was affected by the food effect. With further investigation in toxicology, Pentarlandir UPPTA demonstrated an overall safe toxicology profile. Taking these findings together, Pentarlandir UPPTA is considered to be a safe and efficacious pancoronal antiviral drug candidate that has been advanced to clinical development.
Functionalization of Glucose Oxidase in Organic Solvent: Towards Direct Electrical Communication across Enzyme-Electrode Interface

Enzymatic biosensors based on glucose oxidase has been proven to be one of the effective strategies for the detection of glucose and contributed to health improvements. Therefore, research and debates to date are ongoing in an attempt to find the most effective way to detect this analyte using this enzyme as the recognition center. The 3rd generation biosensors using direct electron transfer (DET) type enzymes are a great way towards practical devices. In this work, we developed a simple method for the functionalization of glucose oxidase with redoxable ferrocene groups in chloroform. The enzyme retained its activity after storage in this organic solvent and after the functionalization procedures. This enzyme functionalization strategy was employed to develop the biosensing monolayer-based platforms for the detection of glucose utilizing the quasi-DET mechanism. As a result of an electrochemical regeneration of the catalytic center, the formation of harmful H2O2 is minimized during enzymatic electrocatalysis.
Fabrication and characterization of a smart film based on cassava starch and pomegranate peel powder for monitoring lamb meat freshness

Abstract Nowadays, the development of pH‐sensitive smart edible films using biopolymers and natural plant extracts (especially those rich in anthocyanins) has attracted much attention. Therefore, in this study, the intelligent edible film was produced and characterized using cassava starch and pomegranate peel powder (PPP) and the possibility of using production films to monitor the freshness of lamb meat. The smart films were prepared using different concentrations of PPP (2, 4, 6, and 8% w/w) and the solvent casting method. The results showed that the incorporation of PPP had a significant effect on the mechanical parameters of the starch films. With increasing the levels of PPP, the color of the films became darker and redder. Increasing the PPP levels also led to an increase in total phenol content (TPC) (from 0 to 13 mg GAE (gallic acid equivalent)/g) and antioxidant activity (from 0% to 70% DPPH (1,1‐diphenyl‐2‐picryl hydrazyl) radical scavenging) of the produced films (p < .05). The intelligent film was used in the lamb meat packaging, and the color of the film changed from red to green during the storage period at 25°C. The amount of total volatile basic nitrogen (TVB‐N) in the meat could be detected by color changes of the intelligent films. Finally, this study demonstrated that the film based on cassava starch and PPP could be used as an intelligent and pH‐sensitive film to monitor the freshness of meat and meat products.
Simultaneous Evolutions of Inner Magnetospheric Plasmaspheric Hiss and EMIC Waves Under the Influence of a Heliospheric Plasma Sheet

Plasmaspheric hiss and electromagnetic ion cyclotron (EMIC) waves are two of the most important magnetospheric plasma waves inside the Earth's high‐density plasmasphere. In this work, utilizing observations from the WIND and Van Allen Probes missions, we investigate the simultaneous evolutions of inner magnetospheric plasmaspheric hiss and EMIC waves under the influence of a heliospheric plasma sheet (HPS). The long duration impingement of high‐density solar wind HPS onto the magnetosphere produced hot anisotropy electrons and protons, and then caused excitations of plasmaspheric hiss and EMIC waves in the duskside plasmasphere (L ∼ 6.75, MLT ∼ 16.85). In contrast, the solar wind decompression associated with the subsequent cessation of the HPS led to decreases in hot electron and proton fluxes, triggering prompt disappearances of the compression‐related plasmaspheric hiss and EMIC waves. The presented results highlight the importance of solar wind conditions for the Earth's space weather and provide new insights into the solar wind‐magnetosphere coupling.
Prevalence and correlates of depressive symptoms among university students: A cross-sectional study

ABSTRACT The prevalence of mental health problems in university students is increasing and attributable to various factors. We examine the protective and risk factors of depressive symptoms among a cross-section of 251 university students. Results showed 40.2% of students reported moderate to severe depressive symptoms. Multiple regression analysis confirmed that perceived stress and maladaptive coping were positively associated with depressive symptoms, whereas adaptive coping and perceived support was inversely related to depressive symptoms. Findings highlight the need for psychological empowerment strategies in students to manage various stressors more effectively and the importance of enhancing social support as a valuable resource for university students.
Environmental extremes and the immune response to exercise

Exercising in hot and cold conditions poses one of the greatest challenges to human homeostasis. Popular belief is that cold exposure increases susceptibility to upper respiratory tract infections, however, evidence to support a link between cold exposure, impaired immune function and increased incidence of infection is not well defined. On the other hand, if heat production during exercise is not effectively dissipated, core body temperature can rise to dangerous levels, thereby placing the individual at risk of developing exertional heat-illness (EHI), or the more serious, and potentially fatal, condition of exertional heat stroke (EHS). In addition to exercising in hot and humid environments, a number of risk factors for EHI/EHS have been identified. Other potential risk factors, which are less well supported, include the circulating inflammatory response that follows a muscle-damaging exercise bout. All together, these conditions might potentially affect athletes and military personnel, which are expected to perform arduous physical activity, often in extreme environments. Hypothermia is common in trauma victims and is associated with an increase in mortality. Its causes are still not well understood. We found (Chapter 4) that after mildhypothermia (Body rectal temperature (Tre) 35.17 ± 0.33 °C) vaccine-stimulated IFN-γ production significantly decreased by 44% suggesting temporary immune suppression. Moreover, despite rewarming and feeding, vaccine-stimulated IFN-γ production did not return to control values within 3-hour, suggesting more prolonged immune suppression, specifically, impaired antimicrobial capacity and increased risk of infection. This might partially explain the increased mortality reported after mild-hypothermia. During exercise heat stress (HS) (Chapter 5), ΔTre was significantly greater following EIMD than in CON (0.52 oC). Therefore, HS was increased during endurance exercise in the heat conducted 30min trial after, and to a much lesser extent, 24h after muscledamaging exercise. These data indicate that EIMD is a likely risk factor for EHI particularly during exercise-heat stress. After a repeated bout of muscle-damaging exercise (EIMD trial 2) (Chapter 6), final Tre during HS was lower (39.25 ± 0.47 oC) than in EIMD trial 1 (39.59 ± 0.49 oC), whilst no differences between repeat trials were observed in control trials (CON). Thus, incorporating a muscle-damaging bout into training is a strategy to reduce the risk of EHI in individuals undertaking heavy exercise with an eccentric heat component. Further research is required clarify the role of thermo-genic activity on innate immune markers during cold exposure needs clarification. In addition, future studies would need to examine the supposed contribution of pyrogenic pathways after muscle damage upon exercise heat strain in more depth.
GAME PROMOTING ENGINEERING DESIGN IN PRE-ENGINEERING CURRICULUM

This paper presents a working-in-progress project that designs a virtual reality (VR) game system to infuse cyberinfrastructure (CI) learning experiences into the pre-engineering classrooms and to promote science and engineering design in context. Using city infrastructure as the theme and engineers solving real-life problems as the scenes, the games of future sustainable city design engage students, particularly prospective and beginning science and engineering students, in CI-enhanced and -enabled science and engineering discovery. More importantly, the games incorporate the access to visualization, simulation and collaboration tools that cater a great interactive and collaborating learning environment for students to digitally explore science and engineering concepts via virtual analysis, design, and production. This paper focuses on the metacognitive and CI tools being conducted by students in various VR game modules, their contributions to student learning, and how the games and tools together fit seamlessly within the pre-engineering curriculum, particularly the Project-Lead-The-Way programming.
TLR Ligands Dependent on the Presence of Associated Isolated Pneumococcal Polysaccharides Are In Vivo Humoral Immune Responses to

We determined whether T cell-independent Ig isotype responses to isolated pneumococcal polysaccharides (PPS) required TLR signaling in vivo. IgG anti-PPS responses to PPS3, PPS14, and C-polysaccharide (C-PS) were virtually undetectable in TLR2 (cid:1) / (cid:1) mice, whereas speciﬁc IgM induction was variably reduced compared with wild-type mice. All PPS-containing preparations induced IL-6 and TNF- (cid:2) from wild-type, but not TLR2 (cid:1) / (cid:1) , macrophages. TLR2 activity was distinct from that of PPS, in that it was phenol extractable. Immunization of wild-type mice with phenol-extracted PPS14 also resulted in a marked reduction in the IgG, although not the IgM-anti-PPS14, response compared with untreated PPS14. The commercial 23-valent PPS vaccine, Pneu-movax-23 also contained TLR ligands (TLR2 and TLR4), which were absolutely critical for the IgG-inducing activity of the vaccine in mice. Finally, the commercial pneumococcal conjugate vaccine, Prevnar, contained a TLR2 ligand(s) that substantially enhanced both the primary and secondary anti-PPS responses in mice, especially the type 1 IgG isotypes. These data strongly suggest the absolute need for a distinct, TLR-dependent second signal for inducing in vivo IgG T cell-independent humoral immune responses to isolated pneumococcal polysaccharide Ags and highlight the potential importance of previously unappreciated copuriﬁed and/or contaminating TLR ligands in PPS vaccine preparations. The Journal of Immunology, 2005, 175: 3084– 3091. second in provided by the concomitant and hith-erto unappreciated presence of TLR ligands within the PPS preparations. We also show that the presence of a TLR2 ligand(s) in the commercial PPS conjugate vaccine, Prevnar (15), up-regulates the induced IgG anti-PPS response. These data provide a mechanism underlying the induction of speciﬁc IgG anti-PS responses in vivo that is consistent with earlier predictions made using the in vitro polyclonal (cid:1)(cid:2) -dex model system (2) and highlight the potential importance of previously unappreciated, copuriﬁed and/or contaminating TLR ligands in PPS vaccine preparations.