Miracle-dz/UniFAR-FTUs huggingface dataset:
University of Birmingham c+ production in Pb–Pb collisions at sNN = 5.02 TeV

A measurement of the production of prompt (cid:2) + c baryons in Pb–Pb collisions at √ s NN = 5 . 02 TeV with the ALICE detector at the LHC is reported. The (cid:2) + c and (cid:2) − c were reconstructed at midrapidity ( | y | < 0 . 5) via the hadronic decay channel (cid:2) + c → pK 0S (and charge conjugate) in the transverse momentum and centrality intervals 6 < p T < 12 GeV/ c and 0–80%. The (cid:2) + c / D 0 ratio, which is sensitive to the charm quark hadronisation mechanisms in the medium, is measured and found to be larger than the ratio measured in minimum-bias pp collisions at √ s = 7 TeV and in p–Pb collisions at √ s NN = 5 . 02 TeV. In particular, the values in p–Pb and Pb–Pb collisions differ by about two standard deviations of the combined statistical and systematic uncertainties in the common p T interval covered by the measurements in the two collision systems. The (cid:2) + c / D 0 ratio is also compared with model calculations including different implementations of charm quark hadronisation. The measured ratio is reproduced by models implementing a pure coalescence scenario, while adding a fragmentation contribution leads to an underestimation. The (cid:2) + c nuclear modiﬁcation factor, R AA , is also presented. The measured values of the R AA of (cid:2) + c , D + s and non-strange D mesons are compatible within the combined statistical and systematic uncertainties. They show, however, a hint of a hierarchy ( R D 0 AA < R D + s AA < R (cid:2) + c AA ) , conceivable with a contribution from coalescence mechanisms to charm hadron formation in the medium.
A Short Survey on Methodology for Stress Recognition

: n this paper we have taken a short survey on methodology for stress recognition from different types of signal like voice, face, and behavior appears in the persons while in stress. Here, some of acoustic features are studied from speech signal to analyze the characteristics and behavior of speech. This survey is done for the purpose of our system which is aim to design for the stress detection and classification related to the student in examination duration. In this, we have major focus on the input type of voice signal from the speech signal. Along with this survey we are going to collect a datasets are used for analysis of emotions for detecting emotions in real time speech.
THE AMERICAN JOURNAL OF MEDICAL SCIENCES AND PHARMACEUTICAL RESEARCH

Mechanical ventilation may be a life-saving medical care utilized in kids in PICU. These critically sick kids are sometimes extensively investigated in PICU. Chest actinism is associate degree irreplaceable investigation in these patients before ventilation.We studied the impact of initial chest actinism on the ultimate outcome of aired kids.Retrospective. Setting: Tertiary care teaching hospital.One hundred and 41 kids were enclosed within the study. Initial chest actinism of all the aired kids was evaluated and outcome of those kids was correlate with the initial actinism at admission.
ArticleAmorphous Solid Dispersions (ASDs): The influence of material properties

Poorly water-soluble drugs pose a significant challenge to developability due to poor oral absorption leading to poor bioavailability. Several approaches exist that improve the oral absorption of such compounds by enhancing the aqueous solubility and/or dissolution rate of the drug. These include chemical modifications such as salts, co-crystals or prodrugs and physical modifications such as complexation, nanocrystals or conversion to amorphous form. Among these formulation strategies, the conversion to amorphous form has been successfully deployed across the pharmaceutical industry, accounting for approximately 30% of the marketed products that require solubility enhancement and making it the most frequently used technology from 2000 to 2020. This article discusses the underlying scientific theory and influence of the active compound, the material properties and manufacturing processes on the selection and design of amorphous solid dispersion (ASD) products as marketed products. Recent advances in the analytical tools to characterize ASDs stability and ability to be processed into suitable, patient-centric dosage forms are also described. The unmet need and regulatory path for the development of novel ASD polymers is finally discussed, including a description of the experimental data that can be used to establish if a new polymer offers sufficient differentiation from the established polymers to warrant advance-
A Methodology for the Estimation of the Wind Generator Economic Efficiency

Abstract Integration of renewable energy sources and the improvement of the technological base may not only reduce the consumption of fossil fuel and environmental load, but also ensure the power supply in regions with difficult fuel delivery or power failures. The main goal of the research is to develop the methodology of evaluation of the wind turbine economic efficiency. The research has demonstrated that the electricity produced from renewable sources may be much more expensive than the electricity purchased from the conventional grid.
OP-JAMI160142 488..495

Background: The widespread adoption of electronic health records allows us to ask evidence-based questions about the need for and benefits of specific clinical interventions in critical-care settings across large populations. Objective: We investigated the prediction of vasopressor administration and weaning in the intensive care unit. Vasopressors are commonly used to control hypotension, and changes in timing and dosage can have a large impact on patient outcomes. Materials and Methods: We considered a cohort of 15 695 intensive care unit patients without orders for reduced care who were alive 30 days post-discharge. A switching-state autoregressive model (SSAM) was trained to predict the multidimensional physiological time series of patients before, during, and after vasopressor administration. The latent states from the SSAM were used as predictors of vasopressor administration and weaning. Results: The unsupervised SSAM features were able to predict patient vasopressor administration and successful patient weaning. Features derived from the SSAM achieved areas under the receiver operating curve of 0.92, 0.88, and 0.71 for predicting ungapped vasopressor administration, gapped vasopressor administration, and vasopressor weaning, respectively. We also demonstrated many cases where our model predicted weaning well in advance of a successful wean. Conclusion: Models that used SSAM features increased performance on both predictive tasks. These improvements may reflect an underlying, and ultimately predictive, latent state detectable from the physiological time series.
Diagnostic and prognostic roles of circ-SHPRH for solid cancers: a meta-analysis

Background: Circ-SHPRH is a novel circular RNA which was down-regulated in various cancer tissues. Several recent studies hinted that circ-SHPRH might function as a diagnostic and prognostic biomarker for solid cancers. This meta-analysis was performed to determine the diagnostic and prognostic roles of circ-SHPRH for these solid cancers. Methods: Publications were searched in PubMed, MEDLINE, Web of Science, Embase, China National Knowledge Infrastructure (CNKI), and Wanfang database. Pooled sensitivity, speci ﬁ city, positive likelihood ratio (PLR), negative likelihood ratio (NLR), diagnostic odds ratio (DOR), and area under the summary receiver operating characteristic curve (SROC) (AUC) with 95% con ﬁ dence interval (95% CI) were calculated to evaluate the diagnostic value of circ-SHPRH. Pooled hazard ratio (HR) with 95% CI was applied to assess the prognostic value of circ-SHPRH. Results: Nine eligible studies, including 4 for diagnosis and 5 for prognosis, were included in this meta-analysis. Pooled sensitivity, speci ﬁ city, PLR, NLR, DOR, and AUC were 0.79 (95% CI: 0.73 – 0.84), 0.75 (95% CI: 0.69 – 0.81), 3.20 (95% CI: 2.53 – 4.06), 0.28 (95% CI: 0.22 – 0.36), 11.27 (95% CI: 7.57 – 16.79), and 0.84 (95% CI: 0.80 – 0.87), respectively. Pooled HR indicated that low circ-SHPRH expression was signi ﬁ cantly associated with poor overall survival (OS) (low vs high, HR=2.22, 95% CI: 1.60 – 3.09). Conclusion: The results of this meta-analysis indicate that circ-SHPRH might be an important diagnostic and prognostic biomarker for various solid cancers.
Casting Design Optimization for Steam Turbine Emergency Stop Valve (ESV) Housing with Computational Casting Simulation Method

Design optimization casting emergency stop valve steam turbine, has been done with casting simulation using Magmasoft v5 software. By simulation, some casting design parameters are changed to get more optimal results. Optimization of the design of castings in this study, obtained by improving the design through changes in pouring system using bottom pouring and optimization of riser design. The result of four design casting simulation ESV housing versus filling velocity, solidification, and porosity have the same trend of location defect that is in the flange and middle body valve connection area. However quality of the simulation results, in design # 4 has a better quality of casting results based on the color gradation seen in the range of 80-90%. Although, there is still a potential defect in critical areas that have low castability. This results can be used as input for the further casting improvement and NDT inspector guidance.
Open Source ERP Adoption-Use and Organisational Performance of Deposit-Taking Saccos in Kenya

The cost and benefits of an ERP system are arguably the reason why Deposit-Taking SACCOs are opting for adoption-use of open source ERP in an effort to achieve organisation performance. Technology adoption is only important if it truly leads to performance improvements and, as such the proper criteria by which to judge whether an ERP investment has been successful rest not simply in determining whether an organization adopts a technology, but whether the technology application or use actually improves performance. The main aim of the study was to evaluate the influence open source ERP adoption-use on the organisational performance of deposit taking SACCOs in Kenya. The study-specific objective was to determine the influence of open source ERP adoption-use on the organisational performance of Deposit-Taking SACCOs in Kenya. The target population was 168 Deposit-taking SACCOs with a sample size of 378 respondents. The questionnaire was used to collect quantitative data. PLS-SEM using smart pls was used to analyse the data. The study concludes that adoption-use of open source ERP will have a significant effect on organisational performance; learning and growth, internal process, customers, and financial indicators. Open source ERP by itself cannot contribute to significant performance improvement or sustainable competitive advantage if organizational resources and work processes are not improved or changed to enable open source ERP to promote organizational performance. The organisation management and regulatory authority should create an enabling environment and policies that will increase the adoption-use of open source ERP by deposit-taking SACCOs in Kenya. Keywords: open source ERP, adoption-use, learning and growth, internal process, customer finance, deposit-taking SACCOs.
Phytoremediation of Metal Component of Oil Spill Site Using Common Vegetables

Seven days old water leaf (talinum triangular) and pig weed (amaranthus viridis) were employed to clean up an oil spill simulated site. Samples of the crude oil, soil and plants were analysed for heavy metals before, during and after the experiments using X-ray Fluorescence techniques. Different parts of the plants such as roots, stems and leaves were harvested and analysed fortnightly till the end of the ten weeks experiment. The results obtained revealed mean concentration (mg/Kg) of heavy metals were of the range: Pb (0.01-1.42); As (0.02-2.02); Cd (0.01-3.42) Cr (0.03-6.14); Ni (3.21-6.42); Mn (4.12-8.46) and V (10.041.22). High values of Bioaccumulation Factor and Translocation Factors evaluated for different metals showed that the amaranthus viridis is an efficient hyperaccumulator. Phytoremediation technique offers the best panacea to remediate vast oil spill lands especially in Niger Delta of Nigeria.
A MAPREDUCE SOLUTION FOR HANDLING LARGE DATA EFFICIENTLY

: Big data is large volume, heterogeneous, distributed data. Big data applications where data collection has grown continuously, it is expensive to manage, capture or extract and process data using existing software tools. With increasing size of data in data warehouse it is expensive to perform data analysis. In recent years, numbers of computation and data intensive scientific data analyses are established. To perform the large scale data mining analyses so as to meet the scalability and performance requirements of big data, several efficient parallel and concurrent algorithms got applied. For data processing, Big data processing framework relay on cluster computers and parallel execution framework provided by MapReduce. MapReduce is a parallel programming model and an associated implementation for processing and generating large data sets. In this paper, we are going to work around MapReduce, use a MapReduce solution for handling large data efficiently, its advantages, disadvantages and how it can be used in integration with other technology.
Title Constraints versus Priors Permalink

There are deep and important philosophical differences between Bayesian and frequentist approaches to quantifying uncertainty. However, some practitioners choose between these approaches primarily on the basis of convenience. For instance, the ability to incorporate parameter constraints is sometimes cited as a reason to use Bayesian methods. This reflects two misunderstandings: First, frequentist methods can indeed incorporate constraints on parameter values. Second, it ignores the crucial question of what the result of the analysis will mean. Bayesian and frequentist measures of uncertainty have similar sounding names but quite different meanings. For instance, Bayesian uncertainties typically involve expectations with respect to the posterior distribution of the parameter, holding the data fixed; frequentist uncertainties typically involve expectations with respect to the distribution of the data, holding the parameter fixed. Bayesian methods, including methods incorporating parameter constraints, require supplementing the constraints with a prior probability distribution for parameter values. This can cause frequentist and Bayesian estimates and their nominal uncertainties to differ substantially, even when the prior is “uninformative. ” This paper gives simple examples where “uninformative” priors are, in fact, extremely informative, and sketches how to measure how much information the prior adds to the constraint. Bayesian methods can have good frequentist behavior, and a frequentist can use Bayesian methods and quantify the uncertainty by frequentist means—but absent a meaningful prior, Bayesian uncertainty measures lack meaning. The paper ends with brief reflections on practice.
A proposal of a fine tuning free formulation of 4d N = 4 super Yang-Mills

Recently, a nonperturbative formulation of 4d N = 4 super Yang-Mills theory which does not require fine tuning at least to all order in perturbation theory has been proposed by combining two-dimensional lattice and matrix model techniques. In this paper we provide an analogous model by utilizing deconstruction approach of Kaplan et al. Two-dimensional lattice with a plane wave deformation is deconstructed from a matrix model and two additional dimensions emerge through the Myers effect. In other words we construct a D1-brane theory from which a D3-brane theory comes out. The action is much simpler than the previous formulation and hence numerical study, which enables us to test the AdS5/CFT4 duality at fully nonperturbative level, becomes much easier. 1 E-mail address : masanori.hanada@weizmann.ac. il 1
University of Birmingham Reward pays the cost of noise reduction in motor and cognitive control

Here we that We devised a dopamine to be a key neuromodulator in mediating motivational effects of reward. We therefore examined how Parkinson’s disease (PD), a condition associated with dopamine depletion, alters the effects of reward. Individuals with PD showed reduced reward sensitivity in their speed and accuracy, consistent in our model with higher noise-control costs. Including a cost of control over noise explains how reward may allow apparent performance limits to be sur-passed. On this view, the pattern of reduced reward sensitivity in PD patients can speciﬁcally be accounted for by a higher cost for controlling noise.
Mobile Enterprise Application Development in Practice: an Analysis of Real-World User Stories

—In development of mobile enterprise applications, saving time is an important factor. Short time to market and always changing technical environments require the ability to adapt to changes. However, these demands are in conﬂict with writing modular, well-thought-out software that allows easy reuse from results of past projects where requirements are often documented in user stories. These short descriptions of ways for a user to interact with the system are often the center of application development. In this paper, we present an analysis of user stories in practice and a categorization of terms used in these stories. We also evaluate how these categorizations relate to algorithmic similarities from information retrieval.
Functional Genomic Analysis Supports Conservation of Function Among Cellulose Synthase-Like A Gene Family Members and Suggests Diverse Roles of Mannans in Plants

Biology Department, Eastern Michigan University, Ypsilanti, Michigan 48197 (A.H.L.); Department of Energy Plant Research Laboratory, Department of Plant Biology, Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, Michigan 48824 (K.K.); Warnell School of Forestry and Natural Resources, University of Georgia, Athens, Georgia 30602 (C.J.N.); Department of Plant Physiology, University of Copenhagen, DK–1353 Copenhagen, Denmark (W.G.T.W., I.S.); and Department of Biological Sciences, University of Rhode Island, Kingston, Rhode Island 02881–0816 (A.W.R.)
CATALASE AND MALONDIALDEHYDE LEVELS: POSSIBLE MARKERS FOR TYPE 2 DIABETES MELLITUS

Background: Diabetes is a chronic and common metabolic disorder with a rapidly increasing prevalence due to population growth, aging, urbanisation and obesity due to physical inactivity characterized by hyperglycemia. Catalase (CAT) is an antioxidative enzyme which plays an important role against oxidative stress-generated complications such as diabetes and cardiovascular diseases. To estimate catalase and malondialdehyde (MDA) levels in type 2 diabetes mellitus (DM) patients. To analyze the relation between catalase, MDA and fasting blood sugar (FBS) in type 2 DM. Methods: The study included hundred, age and sex matched subjects. Blood samples of all subjects were analyzed for fasting blood sugar, catalase and malondialdehyde. Results: Catalase levels were significantly decreased and malondialdehyde levels were significantly increased in type 2 diabetes mellitus as compared to controls. There is positive correlation between MDA and FBS in type 2 diabetes mellitus. Conclusion: Diabetes patients are susceptible to oxidative stress with free radical mediated lipid peroxidation. The results show significant decrease in antioxidant enzyme and increase in MDA in type 2 diabetes mellitus as compared to normal healthy subjects. This suggests that the antioxidant enzyme production is affected in type 2 diabetes mellitus patients leading to higher risk of cell organ damage.
Flexible and Scalable Heterogeneous Integration of GaN HEMTs on Si‐CMOS by Micro‐Transfer‐Printing

Tomorrow's power electronic systems require cost‐saving and more efficient power conversion solutions. The heterogeneous integration of GaN‐based high electron mobility transistors (HEMTs) together with silicon CMOS by micro‐Transfer‐Printing could be a key technology for this. It enables the integration of highly integrated mature CMOS logic functionality with fast GaN HEMT output drivers with very low on‐state and switching losses. The scalability by design measures of the printed HEMT is investigated in terms of drain‐to‐gate spacing and channel width defining breakdown voltage and area‐related parameters like on‐resistance. The design flexibility of the micro‐Transfer‐Printing by printing the HEMTs on top of the CMOS devices without restrictive design rule limits is investigated by CMOS DC parameter comparison and thermal TCAD Design Of Experiment (DOE) study. No electrical or thermal functional limitation of printing the HEMTs directly on top of the CMOS dielectric layer stack was found. This enables the usage of the isolation capabilities of the CMOS dielectric layer stack to enhance the HEMT breakdown voltage.
EXCESSIVE DAYTIME SLEEPINESS AMONG PHYSICAL THERAPY STUDENTS

Introduction: Excessive daytime sleepiness (EDS) is referred to as difficulty staying awake and alert during most of the waking hours of the day resulting in involuntary intervals into drowsiness. Disturbed sleep of an individual can result in adverse health penalties and decreased work potential. In Pakistan, most of the medical fields are under development process and Physical therapy is one of the neglected fields in Pakistan due to poor resources and awareness. Physical Therapy students are considered to be at high risk of developing sleep-related problems as they usually experience poor field satisfaction along with high psychological pressure and academic demands. Therefore, sleep-related problems such as excessive daytime sleepiness, sleep disturbance, and poor sleep quality remain major issues of interest in physical therapy students. Objective: To describe the daytime sleepiness among Physical Therapy Students of Lahore college of physical therapy Pakistan. Methodology: A descriptive cross-sectional study was conducted on physical therapy students of Lahore College of Physical Therapy. A total of 114 students were recruited through nonprobability convenience sampling. Data was noted through a self-administered questionnaire. Epworth scale of sleepiness was used to assess the daytime sleepiness among Physical Therapy students and data was analyzed through SPSS version 21. Results: The majority of participants reported severe daytime sleepiness. In a sample size of 144 (n=114), 11.4% of students reported no daytime sleepiness (score within normal range 1-6), 16.7% of students reported mild to moderate daytime sleepiness (score 7-8), 71.9% of students reported severe daytime sleepiness (score above 9). Conclusion: In conclusion, most physical therapy students suffer from excessive daytime sleepiness. Efforts directed towards educating physical therapy students about proper sleep hygiene can have a positive impact.