Miracle-dz/UniFAR-FTUs huggingface dataset:
High-resolution quantitative trait locus mapping for rice grain quality traits using genotyping by sequencing

Rice is a major food crop that sustains approximately half of the world population. Recent worldwide improvements in the standard of living have increased the demand for high-quality rice. Accurate identification of quantitative trait loci (QTLs) for rice grain quality traits will facilitate rice quality breeding and improvement. In the present study, we performed high-resolution QTL mapping for rice grain quality traits using a genotyping-by-sequencing approach. An F2 population derived from a cross between an elite japonica variety, Koshihikari, and an indica variety, Nona Bokra, was used to construct a high-density genetic map. A total of 3,830 single nucleotide polymorphism markers were mapped to 12 linkage groups spanning a total length of 2,456.4 cM, with an average genetic distance of 0.82 cM. Seven grain quality traits—the percentage of whole grain, percentage of head rice, percentage of area of head rice, transparency, percentage of chalky rice, percentage of chalkiness area, and degree of chalkiness—of the F2 population were investigated. In total, 15 QTLs with logarithm of the odds (LOD) scores >4 were identified, which mapped to chromosomes 6, 7, and 9. These loci include four QTLs for transparency, four for percentage of chalky rice, four for percentage of chalkiness area, and three for degree of chalkiness, accounting for 0.01%–61.64% of the total phenotypic variation. Of these QTLs, only one overlapped with previously reported QTLs, and the others were novel. By comparing the major QTL regions in the rice genome, several key candidate genes reported to play crucial roles in grain quality traits were identified. These findings will expedite the fine mapping of these QTLs and QTL pyramiding, which will facilitate the genetic improvement of rice grain quality.
Clinical outcomes of proximal gastrectomy with gastric tubular reconstruction and total gastrectomy for proximal gastric cancer: A matched cohort study

Background Proximal gastrectomy with gastric tubular reconstruction is a surgical procedure that can preserve function in patients with proximal gastric cancer. However, whether gastric tubular reconstruction with proximal gastrectomy has certain advantage in some aspects over total gastrectomy is controversial. To evaluate the benefit of gastric tubular reconstruction after proximal gastrectomy, we compared gastric tubular reconstruction with total gastrectomy for proximal gastric cancer. Method A total of 351 patients were enrolled. Concurrent total gastrectomy patients matched with the Proximal gastrectomy group in age, sex, body mass index, clinical stage, and ASA score were selected by propensity score matching. Preoperative basic information, perioperative indicators, histopathological features, postoperative complications and nutritional status, reflux were compared between the two groups. Results There was no significant difference in the incidence of reflux between two groups (14.8% and 6.5% respectively, P = 0.085). There were significant differences between the two groups in bowel function recovery (2.29 ± 1.16 vs. 3.01 ± 1.22; P = 0.039) and start of soft diet (4.06 ± 1.81 vs. 4.76 ± 1.69; P = 0.047). There were no significant differences between the two groups in nutritional status one year after surgery. However, the decrease in serum hemoglobin in the TG group at 3 and 6 months after surgery was significantly higher than that in the PG group (P = 0.032 and 0.046, respectively). One month after surgery, %BW loss in TG group was significantly lower than that in the PG group (P = 0.024). Conclusion The Proximal gastrectomy group has better clinical outcome and gastric tubular reconstruction is simple, similar complications and reflux rates, gastric tubular reconstruction may be more suitable for proximal gastric cancer.
Editorial: Highlights in HIV and STIs, 2021/2022

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ROW TRANSFER MATRIX FUNCTIONAL EQUATIONS FOR A–D–E LATTICE MODELS

Determinantal functional equations satisfied by the row transfer matrix eigenvalues of critical A–D–E lattice spin models are presented. These are obtained for models associated with the Lie algebras , , AL, DL and E6,7,8 by exploiting connections with functional equations satisfied by the row transfer matrix eigenvalues of the six-vertex model at rational values of the crossing parameter λ=sπ/h where h is the Coxeter number. In addition, fusion is used to derive special functional equations, called inversion identity hierarchies, which provide the key to the direct calculation of finite-size corrections, central charges and conformal weights for the critical A–D–E lattice models.
Experimental Assessment of Intestinal Damage in Controlled Donation After Circulatory Death for Visceral Transplantation

There is an urgent need to address the shortage of potential multivisceral grafts in order to reduce the average time in waiting list. Since donation after circulatory death (DCD) has been successfully employed for other solid organs, a thorough evaluation of the use of intestinal grafts from DCD is warranted. Here, we have generated a model of Maastricht III DCD in rodents, focusing on the viability of intestinal and multivisceral grafts at five (DCD5) and twenty (DCD20) minutes of cardiac arrest compared to living and brain death donors. DCD groups exhibited time-dependent damage. DCD20 generated substantial intestinal mucosal injury and decreased number of Goblet cells whereas grafts from DCD5 closely resemble those of brain death and living donors groups in terms intestinal morphology, expression of tight junction proteins and number of Paneth and Globet cells. Upon transplantation, intestines from DCD5 showed increased ischemia/reperfusion damage compared to living donor grafts, however mucosal integrity was recovered 48 h after transplantation. No differences in terms of graft rejection, gene expression and absorptive function between DCD5 and living donor were observed at 7 post-transplant days. Collectively, our results highlight DCD as a possible strategy to increase multivisceral donation and transplantation procedures. Graphical Abstract
A combined fracture‐micromechanics model for tensile strain‐softening in brittle materials, based on propagation of interacting microcracks

Strain‐softening is the decline in stress at increasing strain. Although microcracking is a commonly accepted reason for strain‐softening, the majority of theoretical developments involve macroscopic damage evolution laws. To improve this situation, we propose a micromechanics‐based damage evolution law by combining (i) the propagation criterion for a single penny‐shaped crack embedded in an infinite matrix subjected to remote stresses (taken from linear‐elastic fracture mechanics) and (ii) stiffness estimates for representative material volumes comprising interacting microcracks (taken from continuum micromechanics). This combination allows for modelling tensile strain‐softening as a result of propagation of interacting microcracks, i.e. as a microstructural effect. The initial degree of damage, i.e. the initial microcrack size and the number of microcracks per unit volume, implies two different types of model‐predicted tensile strain‐softening behaviour under strain control: (i) continuous strain‐softening, which occurs in case of initial damage above a critical value, and (ii) an instantaneous stress drop at the peak load (‘snap‐back’), which occurs in case of initial damage below a critical value. Copyright © 2006 John Wiley & Sons, Ltd.
Handling "Don't know" survey responses : the case of Japanese voters on party support

The problem of false negatives, people who really have attitudes but refrain from expressing them, could seriously bias the analysis, but has largely been neglected. Using a survey data including a number of “Don’t know” responses, this paper examined whether “Don’t know” respondents had underlying attitudes. We treated these nonresponses as nonignorably missing, in the sense that “Don’t know” responses are related to the answer of the question in some partially unknown way. We proposed a method to estimate parameters in a logit model when the covariates are nonignorably missing. The method simultaneously employed two generalized linear models: the proportional odds model for the response variable “Party-Support”, and the multinomial logit model for the nonresponse. We found that “Don’t know” responses to the Cabinet support question depended on whether the respondents supported the Cabinet, indicating the existence of false negatives. We also found that determining which party to support was based on voters’ ideology, city size and stance toward the Cabinet, even with the false negatives.
Role of Connexin 43 phosphorylation on Serine-368 by PKC in cardiac function and disease

Intercellular communication mediated by gap junction channels and hemichannels composed of Connexin 43 (Cx43) is vital for the propagation of electrical impulses through cardiomyocytes. The carboxyl terminal tail of Cx43 undergoes various post-translational modifications including phosphorylation of its Serine-368 (S368) residue. Protein Kinase C isozymes directly phosphorylate S368 to alter Cx43 function and stability through inducing conformational changes affecting channel permeability or promoting internalization and degradation to reduce intercellular communication between cardiomyocytes. Recent studies have implicated this PKC/Cx43-pS368 circuit in several cardiac-associated diseases. In this review, we describe the molecular and cellular basis of PKC-mediated Cx43 phosphorylation and discuss the implications of Cx43 S368 phosphorylation in the context of various cardiac diseases, such as cardiomyopathy, as well as the therapeutic potential of targeting this pathway.
Origin of the near-band-edge photoluminescence emission in aqueous chemically grown ZnO nanorods

The optical properties of ZnO nanorods realized by an advanced low-temperature aqueous chemical growth on both silicon and plastic substrates are presented. Systematic photoluminescence investigations in the temperature range of 4–293K reveal strong and well-resolved near-band-edge emission even for rods on plastic substrate, and a weak deep-level emission. At intermediate temperatures phonon replicas of excitonic lines are observable. The optimum molar concentration range of the solution for obtaining nanorods of good optical quality is shown to lie between 0.025M and 0.075M. The large linewidth of the near-band-edge emission (∼10meV), its temperature dependence, and the absence of sharp excitonic transitions indicate that this emission is a result of transitions from a band of donor states.
Brain-enriched miR-128: Reduced in exosomes from Parkinson’s patient plasma, improves synaptic integrity, and prevents 6-OHDA mediated neuronal apoptosis

Parkinson’s disease (PD) is a progressive neurodegenerative disorder associated with the death of mid-brain dopaminergic neurons. Unfortunately, no effective cure or diagnostic biomarkers for PD are available yet. To address this, the present study focuses on brain-enriched small non-coding regulatory RNAs called microRNAs (miRNAs) that are released into the circulation packaged inside small extracellular vesicles called exosomes. We collected blood samples from PD patients and isolated exosomes from the plasma. qPCR-based detection revealed a particular neuron-enriched miR-128 to be significantly decreased in the patient-derived exosomes. Interestingly, a concomitant decreased expression of miR-128 was observed in the cellular models of PD. Fluorescent live cell imaging and flow-cytometry revealed that over-expression of miR-128 can prevent 6-OHDA-mediated mitochondrial superoxide production and induction of neuronal death respectively. This neuroprotective effect was found to be induced by miR-128-mediated inhibition of FoxO3a activation, a transcription factor involved in apoptosis. miR-128 over-expression also resulted in down-regulation of pro-apoptotic FoxO3a targets- FasL and PUMA, at both transcript and protein levels. Further downstream, miR-128 over-expression inhibited activation of caspases-8, -9 and -3, preventing both the intrinsic and extrinsic pathways of apoptosis. Additionally, over expression of miR-128 prevented down-regulation of synaptic proteins- Synaptophysin and PSD-95 and attenuated neurite shortening, thereby maintaining overall neuronal integrity. Thus, our study depicts the intracellular role of miR-128 in neuronal apoptosis and neurodegeneration and its implications as a biomarker being detectable in the circulating exosomes of PD patient blood. Thus, characterization of such exosomal brain-enriched miRNAs hold promise for effective detection and diagnosis of PD. Graphical Abstract Schematic representation of the role of brain-enriched miR-128 in Parkinson’s disease pathogenesis and progression.
Rigging and existence of stable currents in null hypersurface of Lorentzian manifold

In this paper, using Rigging techniques, we give some conditions on both the null hypersurface wich aﬀects the existence of stable current screen (or more importantly the nonexistence) of a null hypersurface M of a Lorentzian manifold M . We also gave the generalize version of the theorem relating the geometry to the nonexistence of stable currents in the null hypersurface case in Lorentzian Manifold.
From the Red Keep to Winterfell: Translating Toponyms in High Fantasy Literature from English into Arabic

The recent popularity of the fantasy genre in the Arabic world has seen increased translation activity into Arabic (De Blasio 2019). Despite this interest, scholars have focused their attention on low fantasy, with little attention to high fantasy. This study investigates book five of George R.R Martin’s novel series “A Dance with Dragons (2011), and its Arabic translation رقصة مع التنانين raqsa mc ? ltanani:n (2020) with a specific focus on Toponyms. The study uses textual analysis of the translation of book five of the novel series to determine the translation procedures used, and interviews with the official translator to understand the factors behind the translation choices in the series. The study adopts Aixelá’s 1996 model of culture-specific items (CSI) for the classification of the translation procedures. The results indicate the prevalence of two main translation procedures; conservation and substitution. The two procedures are used to strike a balance between the readability of the text, readers’ expectations, and maintaining the fantasy of the secondary world in which the narrative takes place.
Different Faults and Their Diagnosis Techniques in Three-Phase Squirrel-Cage Induction Motors—A Review

Statistics show that 80% of faults are due to eccentricity in induction motors, promoting many research efforts still devoted to the eccentricity in these motors. This paper classifies different common faults in the stator and rotor. It then presents analysis techniques for faulty induction motors. Four more applied methods in the diagnosis and detection of faults in induction motors are investigated and critiqued. The finite difference method is introduced, and its drawbacks are noted. An equivalent magnetic circuit method is then discussed as a fast but less accurate method. The reduced accuracy of the latter method is due to neglect of the spatial harmonics, the relationship between these harmonics, and time harmonics, and particularly non-linearity of the magnetic materials. An analytical method of winding functions is investigated for the analysis of faulty induction motors. This method also neglects the spatial harmonics and their relationship with time harmonics, which could considerably influence the instant of the fault event. Therefore the finite element method (FEM) is used as a powerful numerical method for analysis of faulty induction motors. However, all the previously methods have the two following drawbacks: I. There is no modeling algorithm that compensates the base fault error data. II. There is no algorithm that could diagnose and distinguish between the levels of faults. Therefore, a combination of FEM and other methods (such as state-space, which can compensate the above-mentioned drawbacks) can be used as a precise, flexible and widely applicable technique for fault diagnosis of faulty induction motors. It is shown that this combination is implemented as an iterative process for prediction and analysis of induction motors. It concludes with some suggestions for future study.
Development and Evaluation of a Web-Based Application for Trauma Nursing Documentation in Thailand: A Feasibility Study

Background: Electronic nursing documentation has advantages for monitoring and improving the quality of trauma nursing documentation. However, electronic nursing documentation has rarely been implemented in Thailand. Objectives: This study aimed to assess the feasibility and nursing satisfaction of a web-based trauma nursing documentation application. Methods: A descriptive cross-sectional survey design was used to assess the feasibility and nursing satisfaction with a web-based trauma nursing documentation application. The application was based on literature review, Advanced Trauma Life Support principles, and the North American Nursing Diagnosis Association. The survey was administered to trauma and emergency department registered nurses in a hospital in Thailand from November 2021 to January 2022. Patient data were also extracted from the web application system for analysis. Results: A total of 59 nurses piloted the web-based application on 79 trauma patients. Of 59 nurses, 45 (76.3%) were female, 44 (74.6%) had worked in the emergency department for more than 5 years, and 49 (83.1%) had no prior experience with using web-based applications. The nurses were satisfied with the application (M = 3.51, SD = 0.62), and they suggested that it was feasible to apply in practice (M = 3.46, SD = 0.79). Conclusion: These preliminary data demonstrate that implementing a web-based application for trauma nursing documentation in the emergency department is feasible and satisfactory to nurses.
Improving model using estimate error for daily inflow forecasting

Inflow forecasting is one of the important components for reservoir operation and resource management. To obtain enhanced accuracy for forecasting reservoir inflow, this paper proposed an improved model for forecasting the inflow of Bhumibol reservoir. The 3,169 records of daily inflow data from June 1, 2008, to February 1, 2017, had been collected to calculate the inflow into the reservoir by using Artificial Neural Networks (ANN) Back-Propagation Learning Algorithm for forecasting the inflow of the reservoir in the main model and error prediction model. The performance of the model can be evaluated by four methods: the coefficient of determination (R2), the Nash-Sutcliffe efficiency (NSE), the Root Mean Square Error (RMSE) and the Mean Absolute Error (MAE). Thus, these proposed main and error prediction models were combined to support the forecast of reservoir inflow. The performance of the proposed model can be evaluated by following measured values: R2 was 0.927, NSE was 0.925, RMSE was 6.805 and MAE was 3.611. This indicates that the improved model provides more accurate value.
Acute and subacute postsurgical pain in women with breast cancer: incidence and associations with biopsychosocial predictors—a secondary analysis of a randomized controlled trial

Some women who undergo breast cancer surgery experience intense and unpleasant acute and subacute postsurgical pain. Presurgical pain expectancy significantly predicts postsurgical pain. Abstract Introduction: Women who undergo breast cancer surgery risk suffering from postsurgical pain long after their surgery. Still, research on postsurgical pain in the subacute phase has been neglected. Objective: This study aims to investigate the incidence, intensity, unpleasantness, and presurgical predictors of acute and subacute postsurgical pain after breast cancer surgery. Methods: The study used an observational design through secondary analyses of the control group in a randomized controlled trial. Data from 102 women undergoing breast cancer surgery were included. Levels of acute and subacute pain intensity and unpleasantness were measured using 100 mm Visual Analogue Scales on the day of surgery and 4 weeks postsurgery. Linear regression analyses were performed to identify presurgical biopsychosocial predictors of acute and subacute postsurgical pain. Results: Average levels of postsurgical pain intensity and unpleasantness were as follows: 22.7 mm for acute pain intensity, 19.0 mm for acute pain unpleasantness, 10.3 mm for subacute pain intensity, and 11.7 mm for subacute pain unpleasantness. Pain expectancy predicted acute pain intensity (R2 = 0.04, p = 0.047) and acute unpleasantness (R2 = 0.06, p = 0.02). Perceived social support inversely predicted acute pain unpleasantness (R2 = 0.04, p = 0.014). Conclusion: Mild and moderate acute pain intensity and unpleasantness are common after breast cancer surgery, whereas levels of subacute pain intensity and unpleasantness are low. Pain expectancy predicts acute postsurgical pain intensity and unpleasantness, whereas expected social support inversely predicts acute postsurgical pain unpleasantness.
Sensitivity calculations for iteratively solved problems

The calculation of sensitivity derivatives of solutions of iteratively solved systems of algebraic equations is investigated. A modified finite difference procedure is presented which improves the accuracy of the calculated derivatives. The procedure is demonstrated for a simple algebraic example as well as an element-by element preconditioned conjugate gradient iterative solution technique applied to truss examples.
ACA-accelerated time domain BEM for 3-D elastodynamics

This paper presents the use of the adaptive cross approximation (ACA) method for the acceleration of the classic time domain boundary element method (BEM) in 3-D elastodynamics. The main advantage of using ACA is that it is based only on the knowledge of the matrix entries; therefore no special treatment of the time domain fundamental solution is required when the coefficient matrix is approximated by using this approach. In order to discretize the boundary integral equation (BIE) we use the collocation method and eight-node discontinuous quadratic element. In the numerical examples, stability of the classic time domain BEM in terms of both the degree of discontinuity of the boundary elements and the time step size is tested, and the compression ratios of the coefficient matrices by using ACA along the time steps are studied.
Ideals with Stable Betti Numbers

Componentwise linear ideals were introduced earlier to generalize the result that the Stanley–Reisner ideal IΔ of a simplicial complex Δ has a linear resolution if and only if its Alexander dual Δ* is Cohen–Macaulay. It turns out that IΔ is componentwise linear if and only if Δ* is sequentially Cohen–Macaulay. In this paper we discuss Betti number properties of componentwise linear ideals. Let I be a graded ideal of a polynomial ring S and Gin(I) the generic initial ideal of I with respect to the reverse lexicographic term order on S. Our main result is that I and Gin(I) admit the same graded Betti numbers if and only if I is componentwise linear. For the proof of this fact, we describe some properties of the Betti diagram of a generic initial ideal. Combinatorial implications for shifted complexes will also be discussed.