Miracle-dz/UniFAR-FTUs huggingface dataset:
State-of-the-Art Review on Current Approaches to Female Inclusiveness in Software Engineering and Computer Science in Higher Education

Software engineering (SE) and computer science (CS) programs in universities worldwide are marked by a gender gap, which subsequently translates into a gender gap at the industry level. However, there are positive activities that can help attract more women to these male-dominant professions. This study maps the literature related to the achievement of gender balance in SE and CS university-level education and identifies future research directions. More specifically, this article reports on a systematic mapping study of female-inclusive SE and CS tertiary education programs. The authors collected 882 publications between 2015 and 2022 from five databases (ACM, IEEE, Scopus, Web of Science, and Science Direct), selecting 143 peer-reviewed papers for further analysis. The results showed that the main academic contributors were researchers from the USA. The majority of the publications contained observations and explanations regarding the gender gap in computing education. However, an important part of the literature considered proposals and practical activities for achieving gender balance in SE and CS programs. Finally, the authors classified the literature related to female-inclusive SE and CS tertiary education programs, identified the main research focuses and regional distribution, and considered ideas for future research.
Can i buy you a drink?: Alcohol as symbolic communication in erotic encounters

The purpose of the study is to clarify the status of alcohol as a form of symbolic communication in the process of erotic contact seeking among members of three social categories of the urban Norwegian population. In 1995, a field observation/depth interview study on alcohol and sexuality was undertaken among patrons of three clubs designed to attract people from different social categories in Oslo. 33 persons (25–52 years) visiting the three clubs were interviewed. The informants were classified on the basis of background and lifestyle as belonging to three different social categories: ‘the chosen ones‘, ‘the traditionals' and ‘the unconventionals’. In all three clubs it seemed to be common for men to offer to buy women drinks. The traditional gender role pattern was evident in all social categories. However, there were also differences among them in this respect. Men of the ‘the chosen ones' category might be described as acting like ‘gentlemen' when offering to buy drinks for women whom they did not know. In contrast, ‘traditional' men acted more like the traditional ‘provider‘, and ‘unconventional' men behaved more like the women's ‘pals’. There are thus consequences for both men's and women's motives for, and reactions to, offering somebody a drink.
Thousands of Novel Transcripts Identified in Mouse Cerebrum, Testis, and ES Cells Based on ribo-minus RNA Sequencing

The high-throughput next-generation sequencing technologies provide an excellent opportunity for the detection of less-abundance transcripts that may not be identifiable by previously available techniques. Here, we report a discovery of thousands of novel transcripts (mostly non-coding RNAs) that are expressed in mouse cerebrum, testis, and embryonic stem (ES) cells, through an in-depth analysis of rmRNA-seq data. These transcripts show significant associations with transcriptional start and elongation signals. At the upstream of these transcripts we observed significant enrichment of histone marks (histone H3 lysine 4 trimethylation, H3K4me3), RNAPII binding sites, and cap analysis of gene expression tags that mark transcriptional start sites. Along the length of these transcripts, we also observed enrichment of histone H3 lysine 36 trimethylation (H3K36me3). Moreover, these transcripts show strong purifying selection in their genomic loci, exonic sequences, and promoter regions, implying functional constraints on the evolution of these transcripts. These results define a collection of novel transcripts in the mouse genome and indicate their potential functions in the mouse tissues and cells.
SyzBridge: Bridging the Gap in Exploitability Assessment of Linux Kernel Bugs in the Linux Ecosystem

—Continuous fuzzing has become an integral part of the Linux kernel ecosystem, discovering thousands of bugs over the past few years. Interestingly, only a tiny fraction of them were turned into real-world exploits that target downstream distributions, e.g., Ubuntu and Fedora. This contradicts the conclusions of existing exploitability assessment tools, which classify hundreds of those bugs as high-risk, implying a high likelihood of exploitability. Our study aims to understand the gap and bridge it. Through our investigation, we realize that the current exploitability assessment tools exclusively test bug exploitability on the upstream Linux, which is for development only; in fact, we find many of them fail to reproduce directly in downstreams. Through a large-scale measurement study of 230 bugs on 43 distros (8,032 bug/distro pairs), we find that each distro only reproduces 19.1% of bugs on average by running the upstream PoCs as root user, and 0.9% without root. Remarkably, both numbers can be significantly improved by 61% and 1300% times respectively through appropriate PoC adaptations, necessitated by environment differences. To this end, we developed SyzBridge, a fully automated system that adapts upstream PoCs to downstream kernels. We further integrate SyzBridge with SyzScope, a state-of-the-art exploitability assessment tool that can identify high-risk exploit primitives, e.g., control flow hijack. Our integrated pipeline successfully identified 53 bugs originated from syzbot that are likely exploitable on downstream distributions, surpassing the mere 5 bugs that were turned into real-world exploits among 5,000 upstream bugs from
CHARACTERISTICS OF PALAEO-EARTHQUAKE ACTIVITY ALONG THE ACTIVE TIANQIAOGOU HUANGYANGCHUAN FAULT ON THE EASTERN SECTION OF THE QILIANSHAN MOUNTAINS

The Tianqiaogou Huangyangchuan Fault (called also Gulang Fault) lies to the east of Lenglongling, the highest peak on the eastern section of the Qilianshan Mountains. It is one of the important active faults in eastern Qilianshan. From west to east, the fault is about 86km long, initiating from Hongyaoxian, extending eastward along Tainqiaogou, Qianjin, Guanjiatai, and Huangyangchuan villages, and ending at Jiapigou. The western segment of the fault is NWW trending, the middle is nearly E W trending and the eastern is NEE trending. Among them, the middle segment is convex slightly to the south. The fault is basically continuous, except that a small step over exists near Guanjiatai village, dividing the fault into two sub segments: the Tianqiaogou sub segment in the west and the Huangyangchuan sub segment in the east. Field investigation revealed that offset landforms are well developed along the fault, such as offset gully, fault scarp, sag pond, offset terrace and alluvial fans. All the offset landforms indicate that the fault was dominated by left lateral strike slip with a component of normal faulting. Tracing along the fault and trenching across 6 typical offset landforms revealed the evidence of Holocene activities and several palaeo earthquakes along the fault. By the use of progressive constraining method, 7 Holocene palaeo earthquakes and one historic earthquake are identified. The occurrence time of these events are determined to be 10,743±342a BP (Event Ⅰ), 9038±39a BP (Event Ⅱ), 6910±438a BP (Event Ⅲ), 4847±185a BP (Event Ⅳ), 3562±190a BP (Event Ⅴ), 2476±194a BP (Event Ⅵ), 1505±253a BP (Event Ⅶ) and 1927AD (Event Ⅷ, possibly the Gulang earthquake). The distribution and recurrence behavior of strong earthquakes along the fault show a distinct linearity and sub periodical recurrence, for which the linear regression equation of event time sequence is T i =1516i-11734. Moreover, during field investigation we found new evidence indicating that surface rupture occurred along the Tianqiaogou Huangyangchuan fault during the Gulang M S8.0 in 1927.
Decadal predictability: How might the startosphere be involved?

How warm, wet, and stormy will the next decade be? This question and how to answer it – decadal climate prediction – is currently generating a large amount of interest in the research community. The interest stems from the growing awareness that climate varies naturally on decadal time scales, both regionally and globally, with large socio-economic consequences, and has the potential to temporarily offset or exacerbate anthropogenic global warming. The aim here is to discuss the current status of decadal prediction and highlight areas where the stratosphere may play an important role.
Engineering of Microbes for Heavy Metal Tolerance: An Approach for Bio Remediation Technology

Use of microorganisms and their enzymes to degrade heavy metal contaminants from the environment, is termed as bioremediation. This chapter majorly deals with heavy metals, their toxicity and their ill effects upon the environment. It depicts how microbes can help to combat the side effect of heavy metal toxicity by stimulating their natural defensive mechanism. In spite of their natural defensive system against metal pollution, still there is an urgent need of utilizing advanced molecular tools to further exaggerate their resistance ability for bioremediation. Earlier accumulation of heavy metals was done through overproduction of various metal binding proteins located in the cytoplasm. Recently cell surface engineering of microbes appears an attractive technology for removal or recovery of metal ions from the environment. To expedite the degradation of pollutant, a number of different molecular tools have been established for improving the microbial strains at molecular and genetic level. Microbial engineering thus, seems a promising approach which elucidates the effect of biotechnological processes used for decontaminating the polluted environment and in the future, humans and animals might gain from these organisms in remediating environmental contamination. However, these genetic modifications should be stable and harmless towards the nature as well as for the microbes itself and any genetic alterations must always ensure the actual pros and cons behind it. Engineering of Microbes for Heavy Metal Tolerance: An Approach for Bio Remediation Technology
Fabry Disease in Women: Genetic Basis, Available Biomarkers, and Clinical Manifestations

Fabry Disease (FD) is a rare lysosomal storage disorder caused by mutations in the GLA gene on the X chromosome, leading to a deficiency in α-galactosidase A (AGAL) enzyme activity. This leads to the accumulation of glycosphingolipids, primarily globotriaosylceramide (Gb3), in vital organs such as the kidneys, heart, and nervous system. While FD was initially considered predominantly affecting males, recent studies have uncovered that heterozygous Fabry women, carrying a single mutated GLA gene, can manifest a wide array of clinical symptoms, challenging the notion of asymptomatic carriers. The mechanisms underlying the diverse clinical manifestations in females remain not fully understood due to X-chromosome inactivation (XCI). XCI also known as “lyonization”, involves the random inactivation of one of the two X chromosomes. This process is considered a potential factor influencing phenotypic variation. This review delves into the complex landscape of FD in women, discussing its genetic basis, the available biomarkers, clinical manifestations, and the potential impact of XCI on disease severity. Additionally, it highlights the challenges faced by heterozygous Fabry women, both in terms of their disease burden and interactions with healthcare professionals. Current treatment options, including enzyme replacement therapy, are discussed, along with the need for healthcare providers to be well-informed about FD in women, ultimately contributing to improved patient care and quality of life.
A lay epidemiological study on coexistent stress in hypertension: Its prevalence, risk factors, and implications in patients’ lives

Introduction: Hypertension poses a global challenge in terms of morbidity and mortality. Worldwide prevalence of hypertension is over 40%. Management of hypertension targets blood pressure control to prevent disease complications. Though stress and hypertension are closely related, stress management is often overlooked in the treatment of hypertension. Aims: (1) To estimate the prevalence of stress in hypertensive patients and (2) to study the associated risk factors of stress and its implications in disease management. Materials and Methods: It was a hospital-based, cross-sectional study done in Western India for 1 year. Data were collected from 400 hypertensive patients attending the selected health institutions using a pretested questionnaire. Chi-square tests were done using Medcalc 10.4. 8.0. Results: The prevalence of stress in hypertensive patients was found to be 84.3%. Only 2.4% of these patients sought help from any health professional for stress. The most common stressors found in the patients were financial dependence on others, living in rented house, having a daughter of marriageable age because of associated dowry, death of a loved one, sleep-related problem, and owing a debt among others. Significant statistical association (P < 0.05) of stress was observed with the type of family and socioeconomic status. A highly significant association (P < 0.001) of stress with religion and residential area (whether urban non-slum, slum, or rural) was observed. Stress in individuals leads to poorer compliance with treatment and blood pressure control. Conclusion: Coexistent stress should be diagnosed and managed in patients of hypertension for proper disease management and control.
The Influence of Good Corporate Governance Mechanisms on Earnings Management with Corporate Social Responsibility as a Moderation Variable in Manufacturing Companies on the Indonesian Stock Exchange

This research aims to determine the effect of good corporate governance mechanisms on earnings management with corporate social responsibility as a moderating variable in food and beverage subsector manufacturing companies on the Indonesia Stock Exchange. This research is quantitative research with a causal nature and data collection techniques obtained through annual reports of food and beverage subsector companies listed on the IDX for the 2018-2022 period. The population in this study were 26 food and beverage subsector companies listed on the Indonesia Stock Exchange (BEI). The non-probability sampling technique in this research is saturated sampling (census). The analysis techniques used are panel data regression techniques and moderated regression analysis. The research results show that independent commissioners have no effect on earnings management. The audit committee has no effect on earnings management. Institutional ownership has a negative and significant effect on earnings management. Managerial ownership has no effect on earnings management. Corporate social responsibility is unable to moderate the influence of independent commissioners on earnings management.
Performance of the Stochastic EM Algorithm for Estimating Mixture Parameters

The aim of the present study is to evaluate the performance of the Stochastic EM (SEM) algorithm for estimating parameters in finite mixture distributions. For that purpose some simulation exercises which are based on the implementation of this algorithm are presented and they provide encouraging results. As a consequence it seems that SEM can offer a useful alternative for overcoming some well-known difficulties arising when the number of mixture components is itself an unknown parameter.
Investigation of optical properties of aging soot

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Efectos del Entrenamiento de la Fuerza Concéntrica Versus Excéntrica en la Estructura y Función del Extensor de Rodilla en Adultos Mayores

espanolBaptista R, Onzi E, Goulart N, Dos Santos LD, Makarewicz G, Vaz M. Efectos del Entrenamiento de la Fuerza Concentrica Versus Excentrica en la Estructura y Funcion del Extensor de Rodilla en Adultos Mayores. JEPonline 2016;19(3):120-132. El proposito de este estudio fue comparar los efectos de un programa de 12-sem de entrenamiento de fuerza excentrica versus concentrica en las propiedades del cuadriceps de hombres de edad avanzada. Veintitres sujetos realizaron extension concentrica de rodilla en un lado y flexion excentrica de rodilla en el lado contralateral al 80% de 5RM. Ambos protocolos aumentaron la fuerza del extensor de la rodilla. La longitud del fasciculo del vasto lateral disminuyo y el angulo de peneacion aumento sin cambios en el grosor del musculo en ambos protocolos. La longitud del tendon patelar aumento luego de ambos protocolos, pero el area de la seccion transversal del tendon aumento solo despues del entrenamiento excentrico. El torque isometrico y dinamico aumento en ambos grupos. El entrenamiento concentrico y excentrico se puede usar con resultados similares en adultos mayores. EnglishThe purpose of this study was to compare the effects of eccentric vs. concentric 12-wk strength training program on the quadriceps properties of elderly men. Twenty-three subjects performed unilateral concentric knee extension on one side and eccentric knee flexion on the contralateral side at 80% of 5 RM. Both protocols increased knee extensor strength. Vastus lateralis fascicle length decreased and pennation angle increased without changes in muscle thickness in both protocols. Patellar tendon length increased after both protocols, but tendon cross-sectional area increased only post-eccentric training. Isometric and dynamic torque increased in both groups. Concentric and eccentric training can be used with similar results in older adults. Copyright of Journal of Exercise Physiology Online is the property of American Society of Exercise Physiologists and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.
Knowledge discovery for Deep Phenotyping serious mental illness from Electronic Mental Health records [version 2; peer review: 2 approved]

Background: Deep Phenotyping is the precise and comprehensive analysis of phenotypic features in which the individual components of the phenotype are observed and described. In UK mental health clinical practice, most clinically relevant information is recorded as free text in the Electronic Health Record, and offers a granularity of information beyond what is expressed in most medical knowledge bases. The SNOMED CT nomenclature potentially offers the means to model such information at scale, yet given a sufficiently large body of clinical text collected over many years, it is difficult to identify the language that clinicians favour to express concepts. Methods: By utilising a large corpus of healthcare data, we sought to make use of semantic modelling and clustering techniques to represent the relationship between the clinical vocabulary of internationally recognised SMI symptoms and the preferred language used by clinicians within a care setting. We explore how such models can be used for discovering novel vocabulary relevant to the task of phenotyping Serious Mental Illness (SMI) with only a small amount of prior knowledge. Results: 20 403 terms were derived and curated via a two stage methodology. The list was reduced to 557 putative concepts based on eliminating redundant information content. These were then organised into 9 distinct categories pertaining to different aspects of psychiatric assessment.
Loss Decoupling for Task-Agnostic Continual Learning

Continual learning requires the model to learn multiple tasks in a sequential order. To perform continual learning, the model must possess the abilities to maintain performance on old tasks (stability) and adapt itself to learn new tasks (plasticity). Task-agnostic problem in continual learning is a challenging problem, in which task identities are not available in the inference stage and hence the model must learn to distinguish all the classes in all the tasks. In task-agnostic problem, the model needs to learn two new objectives for learning a new task, including distinguishing new classes from old classes and distinguishing between different new classes. For task-agnostic problem, replay-based methods are commonly used. These methods update the model with both saved old samples and new samples for continual learning. Most existing replay-based methods mix the two objectives in task-agnostic problem together, inhibiting the models from achieving a good trade-off between stability and plasticity. In this paper, we propose a simple yet effective method, called loss decoupling (LODE), for task-agnostic continual learning. LODE separates the two objectives for the new task by decoupling the loss of the new task. As a result, LODE can assign different weights for different objectives, which provides a way to obtain a better trade-off between stability and plasticity than those methods with coupled loss. Experiments show that LODE can outperform existing state-of-the-art replay-based methods on multiple continual learning datasets.
Recombinant Phytase Modulates Blood Amino Acids and Proteomics Profiles in Pigs Fed with Low-Protein, -Calcium, and -Phosphorous Diets

A beneficial effect of corn-expressed phytase (CEP) on the growth performance of pigs fed with very low-protein (VLP) diets was previously shown. Little is known whether this improvement is related to alterations in the expression profiles of blood proteins and amino acids (AAs). The objective of this study was to investigate whether supplementation of VLP, low-calcium (Ca), and low-P diets with a CEP would alter the blood AAs and protein expression profiles in pigs. Forty-eight pigs were subjected to one of the following groups (n = 8/group) for 4 weeks: positive control (PC), negative control-reduced protein (NC), NC + low-dose CEP (LD), NC + high-dose CEP (HD), LD with reduced Ca/P (LDR), and HD with reduced Ca/P (HDR). Plasma leucine and phenylalanine concentrations were reduced in NC; however, the LD diet recovered the concentration of these AAs. Serum proteomics analysis revealed that proteins involved with growth regulation, such as selenoprotein P were upregulated while the IGF-binding proteins family proteins were differentially expressed in CEP-supplemented groups. Furthermore, a positive correlation was detected between growth and abundance of proteins involved in bone mineralization and muscle structure development. Taken together, CEP improved the blood profile of some essential AAs and affected the expression of proteins involved in the regulation of growth.