Miracle-dz/UniFAR-FTUs huggingface dataset:
What Does an Error Consist in Strategy of Medicine

Errors come into question in strategy of medicine. An aim of medical measures is an achievement of health, and she engages in illness. In addition, the modern paradigm of medicine does not take into account fundamental position of biology that a human organism is the open thermodynamics system that submits to all laws of thermodynamics.
Thermoelectric conversion of waste heat from IC engine‐driven vehicles: A review of its application, issues, and solutions

Thermoelectric generator (TEG) is a promising thermoelectric (TE) conversion technology to effectively recover and convert waste heat from vehicle exhaust into useful energy, ie, electricity. Exhaust TEG (ETEG) is a system that is incorporated into the exhaust manifold of a vehicle. Exhaust TEG comprises of a heat exchanger, TEG modules, heat sink, and power conditioning unit. The present work reviews different vehicular ETEGs based on engine type, engine‐rated power, type and number of TEG module, efficiency of ETEG and TEG, exhaust and coolant temperature, and power output of ETEG. In addition to these, the technical issues faced in these ETEGs are addressed under 2 categories, viz., primary (TEG with low ZT TE material and inefficient heat exchanger and heat sink) and secondary issues (low operating temperature TEG modules and installation position of ETEG). In addition to it, effects of vibration and thermal cycling of exhaust system on TEG modules that may arise in ETEG are also discussed. A review of preventive solutions to the issues is also presented. Finally, the economic aspects of an ETEG are also discussed. The review highlights the need of commercialization of TE materials with ZT > 2, high‐temperature operating range, and segmented TEG modules in large volumes so that their practice can be extended in vehicular applications. Heat exchanger modeling using computational fluid dynamics and interfacing with heat transfer theory is essential to maintain temperature uniformity across the TEG modules. Installation of ETEG in the exhaust pipe should be such that it does not affect the performance of the engine. It is also realized that sturdy TEG modules should be developed for long‐term operation to prevent degradation due to mechanical vibration and thermal cycling of the vehicle. Further, ETEG is economically beneficial in vehicles such as trucks owing to availability of high thermal energy in their exhaust stream.
Distribution Line Equipment and Defect Identification Based on Deep Learning

In this study, UAVs were used to collect data of distribution line resources, and defects in distribution line equipment and construction process were identified through deep learning. Different algorithms are used to identify the defects of distribution line equipment and construction process. The research will ultimately support regional synchronization and online development for intelligent automatic acceptance of the distribution wire UAV.
Kinetochore Structural Plasticity and its Regulation in Saccharomyces cerevisiae

The kinetochore is a multi-protein complex that connects the chromosome with microtubule and pulls the chromosome during chromosome segregation. In yeast, a single kinetochore assembles on a Cse4 nucleosome and attaches to a single microtubule, making it an ideal system for studying the architecture of kinetochore-microtubule interaction, function, and regulation. The inner kinetochore assembles on the centromere and anchors the outer kinetochore that attaches to the dynamic microtubule. The interplay between the kinetochore structure and microtubule dynamics in a living cell has not been studied. I have used a combination of in-house developed quantitative microscopy, genetic techniques and mathematical simulation in the budding yeast, S.cerevisiae , to elucidate a novel structural transition of the kinetochore. During anaphase, the microtubule undergoes rapid depolymerization. Kinetochore tracking of microtubule during this phase is critical for chromosome segregation, but how this tracking is achieved is not well understood. A combination of FRAP and photoconversion on kinetochore proteins have revealed that the kinetochore consists of highly dynamic sub-modules and stable sub-modules. I show that microtubule dynamics significantly affect the dynamic kinetochore sub-modules but not the stable ones. Mathematical modeling of microtubule dynamics and kinetochore attachment has revealed the importance of kinetochore structural transition for microtubule attachment. In addition, I have discovered that kinetochore structural transitions are regulated by known metaphase-anaphase specific pathways. Scm3 is the chaperone responsible for assembling the centromeric nucleosome that contains a specific histone variant Cse4. I helped to identify and characterize a new chaperone for Cse4. I demonstrated that recombinant yCAF-1 can promote the assembly of Cse4 nucleosomes in vitro and at non-centromeric positions, causing problems for chromatin-based processes. In summary, my thesis work has significantly contributed to our understanding of centromere and kinetochore function in budding yeast. I speculate that many of the findings will inform our perspectives on centromere and kinetochore function in higher eukaryotes.
Cultural and Philosophical Understanding of Game-based Learning in STEM Subjects

Several reasons have been linked to the high percentage of failure when it comes to Sciences Technolo-gy, Engineering and Mathematics (STEM) subjects for college freshmen. The Higher Learning Commission during its annual conference in 2013 did find out that the leading factor, motivation, seems to play a significant role to inspire students to get involved in the course work. Much research, both in academic journals and mainstream magazines, has been published on how traditional methods of lecturing are neither engaging nor robust enough for STEM learners. In this paper, the author explores the Game-Based Learning method (GBL) as a promising platform to assistance students in their transition from high school to college level STEM courses. Additionally it also looks into the fundamental reasons why biologically, culturally and philosophically, playing has become an essential tool in engaging the real world without having to assume the risk of unwanted consequences.
El impacto de las reformas a la ley del trabajo sobre la calidad de vida de los trabajadores

Introducción: En la década de los años setenta se consideró al neoliberalismo como la respuesta para paliar los problemas económicos mundiales, el cual pugnaba por la disolución progresiva de las fronteras económicas y políticas. Se pensaba que el libre flujo de dinero desde los países ricos en la región de Europa y Norteamérica hacia las vastas regiones pobres de África, América Latina y Oceanía era suficiente como estrategia para eliminar la pobreza y acabar con las crisis económicas recurrentes. A la par se desarrolla la globalización como un proceso de integración de todas las comunidades alrededor del mundo en los ámbitos económico, político, tecnológico, social y cultural, logrado por el desarrollo sin precedentes de los sistemas de comunicación. Este avance tecnológico favoreció el intercambio de productos y servicios, así como la conexión o movimiento de personas, y facilitó las inversiones y transacciones financieras entre mercados distantes o emergentes, acciones que antiguamente resultaban muy difíciles, altamente costosas o inviables. La combinación de ambos fenómenos ha modificado la forma en que interactúan los países, las empresas y los individuos, de modo que, en esta última parte, ha impactado directamente en el mercado laboral, que a su vez ha modificado el ámbito jurídico y político de muchas regiones del planeta. Para lograr la competitividad solicitada internacionalmente uno de los factores clave fue la aplicación de modificaciones legislativas en materia laboral. En otras palabras, fue el concepto de flexibilización del empleo la base de modificación de la antigua ley para dejar que las fuerzas del mercado definieran su calidad. Objetivo: En este estudio se realiza un comparativo entre la Ley Federal del Trabajo vigente en México respecto a la normativa antecesora, para lo cual se tomaron en cuenta el concepto calidad de vida, así como los indicadores propuestos por diferentes entidades internacionales. Método: Se analizaron los indicadores mencionados bajo un sistema binario de calificación para realizar el acumulado (indicador acumulativo), elemento de comparación. La innovación de esta tarea fue la calificación de cada artículo de la ley en función de los conceptos calidad de vida y bienestar tipificados por las entidades internacionales. Esta propuesta de evaluación de las condiciones laborales de los trabajadores en México se considera más objetiva al abordar el bienestar material, los elementos de seguridad social y de realización personal. Resultados y conclusiones: Se identifica una pérdida de elementos relacionados con la seguridad alimentaria, acceso a salud y educación, así como un retroceso en materia de seguridad laboral según los indicadores internacionales, lo que genera una precariedad laboral. Esto, en términos de desarrollo, constituye un retroceso en cuanto a las características del concepto bienestar.
Omuz Problemlerinde Mulligan Mobilizasyon Yönteminin Etkinliği

Amac: Agri ve hareket kisitliligi ile karakterize omuz problemlerinde Mulligan mobilizasyon yonteminin etkinliginin arastirilmasidir. Yontem: Pubmed, Google Scholar ve Pedro arama motorlari konu ile ilgili randomize kontrollu calismalar acisindan tarandi. Uc arastirmaci baslik, ozet ve tam metin makalelerden potansiyel olarak uygun olanlari secmek icin dahil edilme kriterlerini birbirlerinden bagimsiz olarak uyguladilar. Bulgular: Kriterlere uyan 26 randomize kontrollu calisma derlemeye dahil edildi. Literature gore Mulligan mobilizasyon yonteminin, rotator manset sendromlu, subakromiyal sikisma sendromlu, donuk omuz sendromlu ve omuz agrili hastalarda EHA, agri ve fonksiyon acisindan kisa donemde etkili oldugu gorulmektedir. Sonuc: Rotator manset sendromu, subakromiyal sikisma sendromu, omuz agrisi ve kisitliligi olan hastalar ve donuk omuz sendromu olan hastalarda agriyi azaltmak, eklem hareket kisitliligini ve fonksiyonu artirmak amaciyla Mulligan mobilizasyon yontemi kullanilabilir. Mobilizasyonun egzersiz ile birlikte uygulanmasi daha etkili sonuclar vermektedir.
Retractation Note: Elaboration d'un dispositif d'évaluation diagnostique de l'organisation administrative et pédagogique d'un établissement d'enseignement

The Guest Editors of the proceedings are issuing an editorial concern for this Article. Shortly after publication of this Article in May 2021, the Publisher was alerted by one of the authors Hicham Berbar that he never approved to be listed in the current Authors list. Furthermore, the Author points out that the published paper is a very similar copy to his 2018 PFE report defended at the “Centre de formation des inspecteurs de l’enseignement” (CFIE). The Publisher and the guest editors confirm that Hicham Berbar scientific concern should be addressed. Therefore, this article has been withdrawn from publication.
Elementary Student’s Physical Activity during Pandemic Covid 19

Introduction: Physical activity during the Covid 19 pandemic is essential for primary school students to maintain their physical and mental health. Objective: The purpose of this study was to reveal the physical activity carried out by elementary school students in the upper class with an age range of 10-12 years while staying at home during the Covid 19 pandemic. Method: The research using survey method A total of 122 elementary school students participating, the sampling used was convenience sampling. They have wholeheartedly willing to be involved in this research. Modifiable Activity Questionnaire (MAQ), modified back with the Guttman scale, was used as an instrument in this study. The distribution of the questionnaire using google form assistance started from August to September 2020. The data analysis used was descriptive statistics with a simple percentage distribution. Results: The results showed that male students' activity level was at a moderate activity level, while female students were at a low activity level. This difference occurs because the habits of physical activity and motivation to move are diverse in gender. Supervision from physical education teachers and parents is needed to supervise the physical activities of elementary school students, especially women, while at home during the Covid 19 pandemic.
A TEXT-BASED APPROACH TO INDUSTRY CLASSIFICATION Word 2 Vec application in constructing an industry classification to describe the economic relatedness between companies

Industry classification schemes are a critical topic in academic research due to their use in combining companies into smaller groups that share similar characteristics. Although many studies in the domains of economics, accounting and finance depend heavily on these schemes, existing ones have significant limitations mainly due to their stagnant nature, which makes the schemes incapable of adapting to constant innovation and technological development. The objective of this thesis is to propose an automated, text-based industry classification scheme that can reflect constant changes in industry scope. This thesis approaches the research problem by answering two research questions. First, it studies whether it is possible to build an industry classification scheme by using word-embedding vectors extracted from news article. Second, this thesis identifies the benefits of a text-based industry classification scheme in comparison with existing classification schemes. To identify benefits, both qualitative and quantitative assessments are conducted to measure the performance. In the construction of an industry classification scheme, word-embedding vectors generated from news articles are used. The vectors are built using the Word2Vec algorithm. Word2Vec is a recently developed text-mining tool and is excellent at capturing the relationships between words and expressing them in a quantifiable format. The key findings of this thesis are twofold. First, it is technically possible to build an automated, text-based industry classification scheme by using word-embedding vectors. Two methods of building the scheme are proposed. Second, the proposed text-based scheme performs well in classifying companies into relevant business categories. In addition, the cluster-based scheme exhibits better performance in grouping companies into financially homogenous groups when parameters are optimized. The results suggest that a text-based industry classification scheme can serve as an alternative to existing industry classification schemes if parameters are optimized to the purpose of its use. The usefulness of the scheme is expected to increase due to the accelerating speed of innovation and technological development.
Effect of the pigtail grounding position on crosstalk to aircraft shielded cables

In this article, we introduce an investigation of the effect of the pigtail grounding position on crosstalk to aircraft shielded cables from a numerical and an experimental point of view. The numerical simulation model is built in CST cable studio to predict the crosstalk between the single cable and the shielded cable terminated with pigtails, and the simulation results are validated by the experiment. A low-frequency model for the pigtail section which explains the simulation results is given. Simulated and experimental results show that the difference of the crosstalk transfer ratio between the different pigtail ground positions can reach 20dB.
Running speed does not influence the asymmetry of kinematic variables of the lower limb joints in novice runners

Purpose: The purpose of this study was to evaluate kinematic variables at 5 running speeds (8 to 12 km/h), for the asymmetry between lower limbs. We also investigated the effects of running speed on the bilateral asymmetry of the lower limb joints kinematic variables among novice runners. Methods: Kinematic (200 Hz) running data were collected bilaterally for 17 healthy male novice runners (age: 23.1 ± 1.3 years, height: 1.77 ± 0.04 m, mass: 72.3 ± 4.57 kg, BMI: 23.1 ± 1.0 kg/m2) running on a treadmill at 5 fixed speeds (8, 9, 10, 11 and 12 km/h) in a randomized order. Symmetry angles (SA) were calculated to quantify gait asymmetry magnitude at each running speed. Results: Overall, SPM analysis using paired t-tests revealed significant joints kinematic differences between the left lower limb and the right lower limb at each running speed. Significant differences between limbs were found for all joint kinematic variables in the ankle and hip, regardless of running speed. As for the knee angle, significant differences between legs were only found during the running speed of 11 km/h. For knee angle velocity, significant differences between legs were found in all running speeds except for 8 km/h. However, there was no noticeable difference in asymmetry values across running speeds. Conclusions: The findings of the current study indicate that gait asymmetry of joint kinematics variables between lower limbs during running is apparent in healthy novice runners. Meanwhile, running speed does not influence lower limb joints kinematic asymmetry among novice runners.
The impact of the number of visits and the level of satisfaction on the intention to recommend a tourist destination. The example of Gdańsk

The article focuses on examining the intention to recommend Gdańsk as a tourist destination to family and friends. The study was based on the results of a survey (Bęben et al., 2018) conducted among 2,508 respondents visiting Gdańsk in 2017. The method of cluster analysis was applied, thanks to which it was possible to divide the respondents into three clusters. Then, logistic regression was used to analyze the variables influencing the intention to recommend a destination. The study shows that for the entire sample the level of satisfaction from a visit to Gdańsk remains the factor supporting the decision to recommend a destination. Importantly, the total number of visits to Gdańsk is negatively correlated with the intention to recommend the destination, which proves only partial loyalty. key words Gdańsk, satisfaction, tourism, cluster analysis, logistic regression. received: 24 November 2020 accepted: 19 January 2021 Published: 31 March 2021
High-Fat Diet-Induced Obesity Exacerbates Inflammatory Bowel Disease in Genetically Susceptible Mdr 1 a 2 / 2 Male Mice 1-3

Obesity is a chronic inflammatory disease and a risk factor for disorders such as heart disease, diabetes, and cancer. A highfat diet (HFD), a risk factor for obesity, has also been associated with inflammatory bowel disease (IBD). A proinflammatory state characterized by systemic and local increases in cytokine and chemokine levels are noted in both obesity and IBD, but it is unclear whether obesity is a risk factor for IBD. To examine any association between obesity and IBD, we chose FVB.129P2-Abcb1aN7 (Mdr1a) mice, because this strain develops IBD spontaneously with age without a chemical or bacterial ‘‘trigger. ’’ In addition, its background strain, FVB, has been used for diet-induced obesity studies.Mdr1a mice and wild-type (WT) mice were fed a HFD (;60% calories from fat) or a low-fat diet (LFD;;11% calories from fat) for 12 wk. Obesity phenotypes examined included body weight measurements, glucose metabolism changes, and adiposity at termination of the study. IBDwas determined by clinical signs, necropsy, and histopathology. We found that compared with those fed the LFD, both the Mdr1a and WT mice fed the HFD had greater weight gains and elevated plasma leptin concentrations (P < 0.0001). When all micewere analyzed, weight gainwas also associatedwith inflammation inmesenteric fat (R = 0.5; P < 0.0001) and mesenteric lymph nodes (R = 0.4; P < 0.0001). In contrast, the HFD was not associated with IBD inWTmice, whereas it exacerbated spontaneous IBD inMdr1amice (P = 0.012; Fisher s exact test). Although a HFD and obesity were not associated with IBD in WT mice, our studies suggest that they are likely risk factors for IBD in a genetically susceptible host, such as Mdr1a mice. J. Nutr. doi: 10.3945/jn.113. 174615.
Post-transplant Diabetes Mellitus in Kidney Transplant Recipients: A Multicenter Study

Visual Abstract Abstract Key Points Post-transplant diabetes mellitus (PTDM) occurred commonly in a multicenter longitudinal cohort of 632 kidney transplant recipients. Independent risk factors for PTDM included older recipient age and higher body mass index at time of transplant. PTDM was not associated with adverse graft outcomes or mortality at a median follow-up of 6 years after transplant. Background De novo post-transplant diabetes mellitus (PTDM) is a common complication after kidney transplant (KT). Most recent studies are single center with various approaches to outcome ascertainment. Methods In a multicenter longitudinal cohort of 632 nondiabetic adult kidney recipients transplanted in 2010–2013, we ascertained outcomes through detailed chart review at 13 centers. We hypothesized that donor characteristics, such as sex, HCV infection, and kidney donor profile index (KDPI), and recipient characteristics, such as age, race, BMI, and increased HLA mismatches, would affect the development of PTDM among KT recipients. We defined PTDM as hemoglobin A1c ≥6.5%, pharmacological treatment for diabetes, or documentation of diabetes in electronic medical records. We assessed PTDM risk factors and evaluated for an independent time-updated association between PTDM and graft failure using regression. Results Mean recipient age was 52±14 years, 59% were male, 49% were Black. Cumulative PTDM incidence 5 years post-KT was 29% (186). Independent baseline PTDM risk factors included older recipient age (P<0.001) and higher BMI (P=0.006). PTDM was not associated with all-cause graft failure (adjusted hazard ratio (aHR), 1.10; 95% CI, 0.78 to 1.55), death-censored graft failure (aHR, 0.85; 95% CI, 0.53 to 1.37), or death (aHR, 1.31; 95% CI, 0.84 to 2.05) at median follow-up of 6 (interquartile range, 4.0–6.9) years post-KT. Induction and maintenance immunosuppression were not different between patients who did and did not develop PTDM. Conclusions PTDM occurred commonly, and higher baseline BMI was associated with PTDM. PTDM was not associated with graft failure or mortality during the 6-year follow-up, perhaps due to the short follow-up time.
Revaluation of the available energy of difructose anhydride III and maltobionic acid based on the fermentability of breath hydrogen excretion in healthy humans

ABSTRACT The relative available energy (RAE) based on the fermentability of breath hydrogen excreted by gut microbiota was assessed using a method accepted by the Japanese Society for Dietary Fiber Research. The purpose of this study was to evaluate RAE of difructose anhydride III (DFA III) and maltobionic acid (MA). In this study, which had a within-subject, repeated measures design, 11 healthy female participants ingested 5 g of DFA III, MA, and fructooligosaccharide, which has RAE of 2 kcal/g. Breath hydrogen was collected 12 times up to 14 h after meal consumption and measured using gas chromatography, and the area under the curves (AUCs) was calculated 0–14 h after ingestion. Compared with the AUCs of breath hydrogen excretion related to the ingested fructooligosaccharide for 14 h, those of DFA III and MA were 40.5% and 23.1%, respectively. RAE was 0.81 kcal/g for DFA III and 0.46 kcal/g for MA, respectively.