Miracle-dz/UniFAR-FTUs huggingface dataset:
Resistance exercise: a mighty tool that adapts, destroys, rebuilds and modulates the molecular and structural environment of skeletal muscle

[Purpose] Skeletal muscle regulates health and performance by maintaining or increasing strength and muscle mass. Although the molecular mechanisms in response to resistance exercise (RE) significantly target the activation of protein synthesis, a plethora of other mechanisms and structures must be involved in orchestrating the communication, repair, and restoration of homeostasis after RE stimulation. In practice, RE can be modulated by variations in intensity, continuity and volume, which affect molecular responses and skeletal muscle adaptation. Knowledge of these aspects is important with respect to planning of training programs and assessing the impact of RE training on skeletal muscle. [Methods] In this narrative review, we introduce general aspects of skeletal muscle substructures that adapt in response to RE. We further highlighted the molecular mechanisms that control human skeletal muscle anabolism, degradation, repair and memory in response to acute and repeated RE and linked these aspects to major training variables. [Results] Although RE is a key stimulus for the activation of skeletal muscle anabolism, it also induces myofibrillar damage. Nevertheless, to increase muscle mass accompanied by a corresponding adaptation of the essential substructures of the sarcomeric environment, RE must be continuously repeated. This requires the permanent engagement of molecular mechanisms that re-establish skeletal muscle integrity after each RE–induced muscle damage. [Conclusion] Various molecular regulators coordinately control the adaptation of skeletal muscle after acute and repeated RE and expand their actions far beyond muscle growth. Variations of key resistance training variables likely affect these mechanisms without affecting muscle growth.
Most postoperative reserved “normal” metatarsal stumps of diabetic foot osteomyelitis are infected but have healing potential

Background Although the pathology and bacterial status of the “normal” bone stump after operation of diabetic foot osteomyelitis (DFO) are of great significance for the prognosis of foot wounds, there are only a few studies on this topic; hence, it is clinically relevant and urgent to study this topic. Methods The data of 57 inpatients with DFO from June 2021 to April 2022 were collected, all of whom had DFO in the forefoot and underwent conservative surgery. After the surgical removal of necrotic bone, bone biopsies were taken from the necrotic phalangeal bone and the reserved “normal” metatarsal stump. They were cultured, after which antibiotic susceptibility test and pathological screening were carried out. According to clinical judgment, inpatients’ wounds were divided into metatarsal affected group and metatarsal unaffected group. We then compared and analyzed the pathological and bacterial characteristics of preserved “normal” bone stump and its effect on wound healing and prognosis. Results The poor concordance rate between deep soft tissue culture and infected phalange culture was only 19.3%. The deep soft tissue (72.6%), infected phalange (70.7%), and metatarsal stump (71.4%) were mainly infected with gram-negative Bacillus. The proportion of Enterococcus spp. increased significantly in bone tissue. Acinetobacter baumannii had the highest drug resistance (88%, 22/25). There was no significant difference in several clinical characteristics and wound healing regardless of whether their metatarsal stumps were affected. Most reserved “normal” metatarsal stumps (84.2%, 48/57) were positive by pathological diagnosis and bacterial culture testing; only 15.7% (9/57) samples were truly sterile. Only 8.3% (4/48) of the former patients healed within 6 months; whereas, all the latter (9/9) patients healed within 6 months. However, the majority (89.6%, 43/48) could heal. There was no difference in operations, skin grafting, negative pressure wound therapy, and mortality between the two groups. Conclusion The most reserved “normal” metatarsal stumps have been invaded by bacteria. However, the majority stumps can be preserved, and the wound will eventually be healed according to the pathological and bacterial culture results.
Application of Gene Expression Programming (GEP) in Power Transformers Fault Diagnosis Using DGA

Accurate diagnosis of incipient faults in oil-filled power transformers is important in preventive maintenance of transformers. Dissolved gas analysis (DGA) is an effective tool to diagnose incipient transformer faults. The majority of the methods reported in literature to analyze DGA results lay more emphasis on user experience rather than mathematical formulation/justification. Furthermore, sometimes DGA results for a certain fault do not belong to any of the IEC/IEEE standard and cannot be categorized/diagnosed. To address these issues, we propose a new approach for DGA interpretation using gene expression programming (GEP). The proposed approach is employed for analysis of 552 DGA samples collected from transformers of Himachal Pradesh State Electricity Board, India, in conjunction with samples extracted from reliable literature. We use the aforementioned dataset to test and validate our proposed GEP model. We also compare the performance of our approach against other artificial intelligence-based techniques such as artificial neural network, fuzzy-logic, and support vector machine. Results and comparison against other soft computing approaches show relative superiority of GEP-based DGA interpretation in terms of classification accuracy.
Probability and quantum symmetries. I. The theorem of Noether in Schrödinger's euclidean quantum mechanics

Le Theoreme de Noether de la mecanique lagrangienne classique, dans le cas des lagrangiens quadratiques par rapport aux vitesses, est etendu a une classe de processus de diffusion a valeurs dans R 3 , dont la matrice de diffusion est proportionnelle a l'identite. Lorsque la constante de proportionnalite se reduit a zero, nous retrouvons le theoreme usuel. Nous montrons que ce resultat s'interprete en terme d'integrale de Feynman dans le cadre de la mecanique quantique non relativiste. Par prolongement analytique par rapport a la variable temporelle, ce resultat fournit un nouveau Theoreme concernant les symetries de la mecanique quantique usuelle.
Government expenditure impacts on financial development: Do population age structures moderations matter?

PurposeThis study examined the roles of public spending and population moderating characteristic structure of selected African economies on bank-based financial development through credit to private sector.Design/methodology/approachThe study sampled 37 selected African economies for the years 1991–2018, and it applied a pooled mean group (PMG) estimator to account for short-run and long-run causal effects, and confirmed short-run adjustments towards the long-run convergences between the variables. Specific suitable tests were also applied.FindingsEvidence confirms positive impacts of both capital formation and final consumption expenditures on financial development in the short run and long run. The moderation of population structures on expenditure structures help to speed up convergences.Originality/valueThis work attests its innovation by accounting for the separate effects of the expenditure types, the moderation effects of young and mature populations for capital and final consumption expenditure on financial development among selected economies in Africa.
Clustering Hashtags Based on New Hybrid Method and Power Links

 Abstract — It is very important for various apps to cluster hashtags accurately. Some clustering methods depend on text properties. Since in social media there is complete freedom for users, there much spelling and grammar errors that might make dependence on lexical properties is useless. On the other hand, depending on the metadata of wordnet also affected by the users spelling and grammar errors. Hybrid methods might improve the accuracy of clustering for some extent. In this work, an un-supervised method for clustering hashtags based on text properties, semantic metadata, and power links is presented. The semantic method and lexical method will be combined in a strictly different way to produce a new hybrid method. The proposed hybrid method is supported through Power links to refine the clusters. The experiments proved that the proposed method outperforms each method individually and, also, outperform past hybrid methods. In all results, it is never happened that previous method achieved better results than the proposed method.
Editorial: Pannexin and connexin signaling in cell death and tissue health and disease

This Research Topic of Frontiers in Cell and Developmental Biology, “Pannexin and connexin signaling in cell death and tissue health and disease,” brings together seven new articles exemplifying the role of connexin and pannexin signaling in human health, with the aim of increasing understanding of the biology of this area and feeding into work developing novel related therapies. The first time that gap junctions were associated with a human disease was in 1966, when Loewenstein and Kanno observed a lack of gap junctional intercellular communication between liver cancer cells (Loewenstein and Kanno, 1966). During the following five decades, this association has been confirmed in many in vitro and in vivomodels; however, there is yet no clear answer about the precise molecular involvement of gap junctions and their constitutive proteins, the connexins, in tumor progression. How connexins are involved in cancer cell growth and/or invasion is still an open question, whose possible answers depend on tumor stage and cancer type. The lack of clear molecular mechanisms linking connexin signaling to cancer is probably due to the complexity of the disease evolution and heterogeneity of its microenvironment (Aasen et al., 2019). Since the seminal observation of Loewenstein and Kanno, it took almost 30 years to causally link connexin gene mutations to a human disease (in X-linked Charcot-MarieTooth disease) outside the cancer field (Bergoffen et al., 1993). This finding was unexpected, as the particular connexin, Connexin32 (Cx32), which was thought to be an epithelialspecific connexin, was identified in Schwann cells with a critical role in myelin maintenance. This work inspired the description of many more connexin-related genetic diseases, growing over 20 years, with the parallel discovery of new connexin isoforms, establishing connexins as members of a multigene family. Connexinmutations are now known to cause a wide range of genetic diseases affecting hearing (cochlea), skin keratinization, heart function, lens transparency, etc., (Srinivas et al., 2018). Many of these discoveries were confirmed by the increased use of transgenic strategies in mice permitting visualization of the pathophysiological effects of modulating connexin expression. In parallel, investigations of connexin function and biology showed that at least some connexins could not only mediate direct intercellular communication through gap junctions, but also communicate between intracellular and extracellular domains through unopposed connexin channels (connexons) in the plasma membrane. This so-called hemichannel OPEN ACCESS
The Impact of Mobile Phone Addiction on Education, Mental and Physical Health among University Students in Bangladesh

Mobile phone is a great invention of the modern science which was invented for making our life easy and comfortable, but it is not only confined into benediction side, rater it has turned into addiction and malediction as well. It has become a worldwide problem. The hitch is being so accelerated that the future of our next generation is under a massive threat. Day by day the problem is growing severe. The university students, the future of our nation as well as the ordinary people of the world are also no exception of the addiction. Therefore, this study aims to identify the prevalence and extent of mobile addiction among university students so that how long in a day they use mobile phone can be identified. Besides, the study tries to explore the factors contributing to mobile addiction among them, in consequence the positive and negative aspects towards their education, physical and mental health can be recognized. Apart from these, the study examines the impact of mobile addiction on the academic performance, mental and physical health of university students as well. For the study quantitative and qualitative components have been implemented where a cross-sectional survey design is ensured. The quantitative aspect involves conducting a survey among 12 university students (6 public and 6 private universities) in Bangladesh to investigate the current situation of mobile device addiction on educational studies and psychological sound health. The survey conducted through online . To ensures a diverse representation of participants from various faculties and academic levels, a stratified random sampling method has been utilized for participant selection. As a result, it has been found that it carries both positive and negative aspects. But most of the students are impacted negatively. Consequently they are going to lose a good career, a sound physical and mental health and better life.
COMPARATIVE STUDY OF SIMULATED AND OFFICIAL BASKETBALL MATCHES ON SELECTED PHYSIOLOGICAL PARAMETERS

_____________________________________________________________________________ The purpose of this study was to compare the physiological responses between simulated and official basketball matches. The physiological parameters chosen were heart-rate measured by counting beats at the radial artery(beats/min), blood-pressure by sphygmomanometer(mm Hg), peak flow rate by peak flow meter (lit/min) and blood glucose level was measured by glucometer respectively. Five female basketball players of L.N. U.P.E. team were purposively selected as the subjects for study. The measurements of Physiological Variables were first taken in Simulated Matches during their practice session and then in Official Matches during their west zone inter-varsity competition. Pre data were collected after pre match warm-up and post after the end of match. The data collected in the different simulated and official basketball matches were analysed by ANCOVA for each variable separately. The results from ANCOVA showed significant differences for Heart-rate, Systolic blood pressure, and Blood Glucose level whereas no significant differences were found in Diastolic blood pressure and Peak flow rate between Simulated and Official Matches.The results of this study showed a greater magnitude of Heart-rate, Systolic blood pressure and Blood Glucose response after Official Matches as compared with that after Simulated Matches confirming the hypothesis that a real competition generates a greater response than a training condition.
Measuring Quality of Life in Adults with Scoliosis: A Cross-Sectional Study Comparing SRS-22 and ISYQOL Questionnaires

Idiopathic scoliosis is common in adulthood and can impact patients’ physical and psychological health. The Scoliosis Research Society-22 Questionnaire (SRS-22) has been designed to assess health-related quality of life (HRQOL) in idiopathic scoliosis, and it is the most used disease-specific outcome tool from adolescence to adulthood. More recently, the Italian Spine Youth Quality of Life (ISYQOL) international questionnaire was developed, which performs better than SRS-22 in adolescent spinal deformities. However, the ISYQOL questionnaire has never been tested in adults. This study compares the construct validity of ISYQOL and SRS-22 with the Rasch analysis (partial credit model). We recruited 150 adults and 50 adolescents with scoliosis (≥30° Cobb). SRS-22, but not ISQYOL, showed disordered categories and one item not fitting the Rasch model. A 21-item SRS-22 version with revised categories was arranged and further compared to ISYQOL. Both questionnaires showed multidimensionality, and some items (SRS-22 in a greater number) functioned differently in persons of different ages. However, the artefacts caused by multidimensionality and differential functioning had a low impact on the questionnaires’ measures. The construct validity of ISYQOL International and the revised SRS-22 are comparable. Both questionnaires (but not the original SRS-22) can return measures of disease burden in adults with scoliosis.
A Three-Phase Modularization Approach of OXC for Large-Scale ROADM

In recent years, multiple optical fibers are installed on each optical link to deal with the surge of Internet traffic, which calls for large-scale reconfigurable optical add/drop multiplexers (ROADMs). However, the scalability of the standard optical cross-connect (OXC), the key component of ROADM, is limited by the port count of commercial wavelength selective switches (WSSs). The theory of Clos network could be used to design a scalable OXC, but it will lead to a large insertion loss (∼30 dB). To address this issue, we propose a three-phase approach to construct a modular OXC network. Starting from a classical OXC, phase 1 decomposes each WSS in the input and output stages into a two-stage cascaded structure of WSSs, based on which phase 2 factorizes the shuffle network between the inputs and the outputs of the original OXC into the interconnection of small-size shuffle networks. Phase 3 combines the small-size shuffle networks together with the small-size WSSs to form small-size OXC modules. As a result, we obtain a modular OXC network, which is an interconnection of small-size OXCs. The modular OXC network is a strictly nonblocking and flex-grid optical switching fabric and has ∼20-dB insertion loss. At last, we experimentally evaluate the transmission performance of modular OXC network and discuss the related issues when it is deployed in a ROADM.
Peer-review practices of psychological journals: The fate of published articles, submitted again

Abstract A growing interest in and concern about the adequacy and fairness of modern peer-review practices in publication and funding are apparent across a wide range of scientific disciplines. Although questions about reliability, accountability, reviewer bias, and competence have been raised, there has been very little direct research on these variables. The present investigation was an attempt to study the peer-review process directly, in the natural setting of actual journal referee evaluations of submitted manuscripts. As test materials we selected 12 already published research articles by investigators from prestigious and highly productive American psychology departments, one article from each of 12 highly regarded and widely read American psychology journals with high rejection rates (80%) and nonblind refereeing practices. With fictitious names and institutions substituted for the original ones (e.g., Tri-Valley Center for Human Potential), the altered manuscripts were formally resubmitted to the journals that had originally refereed and published them 18 to 32 months earlier. Of the sample of 38 editors and reviewers, only three (8%) detected the resubmissions. This result allowed nine of the 12 articles to continue through the review process to receive an actual evaluation: eight of the nine were rejected. Sixteen of the 18 referees (89%) recommended against publication and the editors concurred. The grounds for rejection were in many cases described as “serious methodological flaws. ” A number of possible interpretations of these data are reviewed and evaluated.
Mid-infrared circular polarization switching in helical metamaterials

Circular polarization switching in helical metamaterial structures in the mid-infrared regime is numerically demonstrated. The low loss and broad transmission of right- and left-circularly polarized waves is found within the circular polarization switching bands. The switching behavior is maintained until the helix pitch or helix height reaches a quarter of the operating wavelength in the conventional and connected 4-layer planar helices, while the electromagnetic couplings among the four quarter helical parts conserve the ‘helical-like’ properties for the free-stand 4-layer planar helices, when the helix height is up to one eighth of the operating wavelength. These different helical orientations can be favorable in circular polarization switching and optical and light applications. Since the transmission switching bands are greater than 25% bandwidth, these switching designs could operate in the broadband spectral domain.
Motor Cycle Long Jump

The practice of long jumping a motor cycle from an inclined ramp over obstacles such as parked buses has become popular with stunt-men. There have been serious accidents, some with fatal results. Some crashes have been caused by the faulty technique of keeping the throttle wide open after leaving the take-off ramp. In some cases this can lead to a backward rotation of the cycle by up to 90° during the jump, with inevitable disaster on landing.
Traveling At The Speed Of Thought Einstein And The Quest For Gravitational Waves

Thank you very much for reading traveling at the speed of thought einstein and the quest for gravitational waves. As you may know, people have search hundreds times for their chosen readings like this traveling at the speed of thought einstein and the quest for gravitational waves, but end up in infectious downloads. Rather than reading a good book with a cup of tea in the afternoon, instead they juggled with some infectious bugs inside their desktop computer.
Higher Dimensional Gravity and Local AdS Symmetry

The most general theory of gravity in d-dimensions which leads to second order field equations for the metric has [(d-1)/2] free parameters. It is shown that requiring the theory to have the maximum possible number of degrees of freedom, fixes these parameters in terms of the gravitational and the cosmological constants. In odd dimensions, the Lagrangian is a Chern-Simons form for the (A)dS or Poincare groups. In even dimensions, the action has a Born-Infeld-like form. Torsion may occur explicitly in the Lagrangian in the parity-odd sector and the torsional pieces respect local (A)dS symmetry for d=4k-1 only. These torsional Lagrangians are related to the Chern-Pontryagin characters for the (A)dS group. The additional coefficients in front of these new terms in the Lagrangian are shown to be quantized.
Estimates of the Natural Rate of Interest for Russia: Is ‘Navigating by the Stars’ Useful?1

We estimate the natural rate of interest for Russia in the short term and long term using three definitions of the rate and discuss the possible implications of the results for monetary policy. To start with, we consider partial equilibrium (under no-arbitrage condition), which is presented in the papers on estimating the natural rate. The estimates turn out to be extremely sensitive to assumptions about model parameters. The estimates based on the uncovered interest rate parity, though dependent only on observable (market) variables, impose an additional strong assumption of the path of the future equilibrium exchange rate. We supplement these calculations with calculations in panel data (for long-term equilibrium) and using semi-structural methods (for current equilibrium). To get estimates according to the strict definition of the natural rate we estimate a real business cycle model of the resource-based economy with investments using Russian data. All the estimates are highly uncertain. Taking into account the latter, the central bank should use robust monetary policy rules and avoid communicating the natural rate at least until there has been a sufficient history of business cycles in Russia.