Miracle-dz/UniFAR-FTUs huggingface dataset:
A SURVEY ON LIGHTWEIGHT METHODOLOGY USED FOR SOFTWARE DEVELOPMENT

: Lightweight methodology that utilizes iterative development and prototyping are widely used in variety of software industry projects which can satisfy to the changes of requirements. Little iterations are used that are required for efficient product delivery. Traditional software development processes are not much efficient to manage the rapid change in requirements. Despite the advantages of Lightweight methodology’s a state that it fails to pay attention to architectural and design issues and therefore is bound to produce small design-decisions. Here, in this paper we identify the impacts that Lightweight methodology has on software development processes with respect to quality within the organizational, methodical, and cultural framework.
Desvendando a Camada de Aplicação na Internet das Coisas: Teoria, Prática e Tendências

The Internet of Things (IoT) is a reality that is already part of our daily lives. In this context, it is essential to understand the fundamentals of prominent protocols, especially at the application layer level, as well as aspects for implementing solutions for IoT. In this document, we introduce the application layer and its protocolos, namely MQTT, CoAP, MQTT-SN, XMPP and DDS. In addition, MQTT and CoAP protocols are presented in practice, as both have been gaining prominence in the literature and the industry, repre-senting two alternatives for the IoT application layer. Finally, potential applications and trends in areas, namely: security, machine learning, computational paradigms, cyber-physical systems and user interfaces are addressed in order to provide insights to readers and encourage them to the development of IoT applications.
EN ALEACIONES BASE Zr-Nb THEORETICAL AND NUMERICAL STUDY OF HYDROGEN DIFFUSION IN Zr-Nb ALLOYS

En el marco de los problemas de fisuración asistida por hidruros en los tubos de presión de los reactores nucleares tipo CANDU, estudiamos la influencia de la fase continua Zr-β (∼ 20% Nb ∼ 80% Zr) sobre el coeficiente de difusión del hidrógeno, DH , en las aleaciones bifásicas Zr-α / Zr-β . Proponemos un modelo fenomenológico de la difusión en tubos que constituye una mejora respecto de otros disponibles en literatura. También estudiamos la influencia del contenido de Nb sobre el DH en la fase Zr-β (cúbica) empleando la teoría del estado de transición, provista de parámetros ab-initio calculados con el código SIESTA. En particular, consideramos 9 aleaciones ordenadas con distintas concentraciones de Nb, y determinamos energías de activación efectivas mediante ajustes de Arrhenius para cada aleación. Encontramos que la concentració de Nb varía la energía de activación de forma no monótona, pasando por un máximo para Zr-50%Nb. Finalmente, observamos que la mayor difusividad en la dirección longitudinal (o axial) del tubo vs. la radial, predicha y medida, es consistente con la microestructura texturada del material. Concluimos que la pérdida de continuidad de las láminas de Zr-β presentes en la microestructura de los tubos de presión, es consistente con la disminución de DH a medida que trascurre el tiempo a una dada temperatura.
Global, regional and seasonal analysis of total ozone trends derived from the 1995–2020 GTO-ECV climate data record

Abstract. In this study we present an updated perspective on near-global total ozone trends for the period 1995–2020. We use the GOME-type Total Ozone Essential Climate Variable (GTO-ECV) satellite data record which has been extended and generated as part of the European Space Agency’s Climate Change Initiative (ESA-CCI) and European Union Copernicus Climate Change Service (EU-C3S) ozone projects. The focus of our work is the analysis of regional patterns in the ozone trend as well as the investigation of its seasonal dependence. In the Southern Hemisphere we found regions that indicate statistically significant positive trends increasing from 0.6 ± 0.5 % decade−1 in the subtropics to 1.0 ± 0.9 % decade−1 in the middle latitudes and 2.8 ± 2.6 % decade−1 in the latitude band 60°–70° S. In the middle latitudes of the Northern Hemisphere the trend exhibits distinct regional patterns, i.e. latitudinal and longitudinal structures. Significant positive trends (∼1.5 ± 1.0 % decade−1) over the North Atlantic region as well as negative trends (−1.0 ± 1.0 % decade−1) over Eastern Europe were found. Moreover, these trends indicate a correlation with long-term changes in tropopause pressure. Total ozone trends in the tropics are not significant. Regarding the seasonal dependence of the trends we found only very small variations over the course of the year. However, we identified different behavior depending on latitude. In the latitude band 40°–70° N the positive trend maximizes in boreal winter from December to February. In the middle latitudes of the Southern Hemisphere (35°–50° S) the trend is maximum from March to May. Further south toward the high latitudes (55°–70° S) the trend denotes a relatively strong seasonal cycle which varies from 2 % decade−1 in December and January to 3.8 % decade−1 in June and July.
Retrosirnulation of a space traveling-wave tube 250 W, Ka-band, 4-stages collector

The internship is dedicated to the modeling of RF and electrical performances of a 250 W Ka traveling- wave tube, using computation codes developed internally. The objective was to compare simulations and measurements in order to design a 5-stages collector. The modeling of the interaction wave -beam (RF model) is discussed in the ﬁrst part. Simulations are done with the internal code MVTRAD. In particular, the gain (at saturation and small signal), the output power and the phase shift are simulated and compared to measurements. Then, we model the collector with the internal code COLLECTD. We look at the electron trajectories and velocities in the collector and we compare the current collected on each electrode to the measurement. Discrepancies have been found between simulations and measurements so that the codes have not been found reliable enough for creating a new design. The objective of the internship changed and we focused on understanding the collector simulation discrepancies. (Less)
Articulating excellence in the context of design and employability

In today's highly competitive graduate marketplace, employability is at the top of the agenda for many academic institutions. At a time when the costs associated with higher education are increasing, the value of attending higher education is being scrutinized more than ever. During open days parents of applicants regularly ask questions indicating how much they value the employability aspects of a programme. According to the CBI, âemployers are looking beyond simple academic achievement when considering applicants for a job or internship. Employability covers a broad range of nonacademic or softer skills and abilities, which are of value in the workplace. It includes the ability to work in a team; a willingness to demonstrate initiative and original thought; self-discipline in starting and completing tasks to deadline. â Attributes such as original thought, problem solving, innovation, creativity, and teamwork are complex skills which employersâ value but are difficult to evidence and articulate. This paper reports a case study of a level three design based assignment, which provides an opportunity for students to reflect upon the qualities they have personally gained through their time at university and to practice communicating and evidencing those skills. The paper covers how the assignment is delivered including engagement with employers and methods of assessment.
Drug delivery to the intestinal lymph by oral formulations

Abstract Oral drug delivery systems (DDS) targeting lymphocytes in intestinal lymphatic vessels, ducts, and nodes are useful for treating diverse diseases. The intestinal lymph harbors numerous lymphocyte subsets, and DDS containing lipids such as triglycerides and fatty acids can deliver drugs to the lymph through the chylomicron pathway. DDS are efficient, thus allowing the administration of reduced drug doses, which mitigate systemic adverse effects. Here we review orally administered lipid formulations comprising oil solutions, suspensions, micro/nanoemulsions, self-micro/nano emulsifying DDS, liposomes, micelles, solid lipid nanoparticles, and nanostructured lipid carriers for targeting drugs to the lymph. We first describe the structures of lymphatic vessels and lymph nodes and the oral absorption of lipids and drugs into the intestinal lymph. We next summarize the effects of the properties and amounts of lipids and drugs delivered into the lymph and lymphocytes, as well as their effects on drug delivery ratios of lymph to blood. Finally, we describe lymphatic DDS containing saquinavir, tacrolimus, and methotrexate, and their potency that reduces drug concentrations in blood, which are associated with systemic adverse effects. Graphical Abstract
Ormolu : generating runtime monitors from alloy models

This thesis presents Ormolu, a runtime monitor used for monitoring distributed systems. Given an Alloy model, Ormolu generates a database schema and translates the constraints of the model to queries over the database. The translation preserves the semantics of Alloy, especially in regards to its type system. Ormolu allows domain specific knowledge to be expressed in Alloy, where it can be checked and verified. The same model can then be used to check if the constraints of the model are still satisfied at runtime. The feasibility of Ormolu is examined in the domain of air traffic control at a local airport, using data provided by the Tower Flight Data Manager developed by Lincoln Laboratory. Thesis Supervisor: Daniel N. Jackson Title: Professor
Customer Churn in Retail E-Commerce Business: Spatial and Machine Learning Approach

This study is a comprehensive and modern approach to predict customer churn in the example of an e-commerce retail store operating in Brazil. Our approach consists of three stages in which we combine and use three different datasets: numerical data on orders, textual after-purchase reviews and socio-geo-demographic data from the census. At the pre-processing stage, we find topics from text reviews using Latent Dirichlet Allocation, Dirichlet Multinomial Mixture and Gibbs sampling. In the spatial analysis, we apply DBSCAN to get rural/urban locations and analyse neighbourhoods of customers located with zip codes. At the modelling stage, we apply machine learning extreme gradient boosting and logistic regression. The quality of models is verified with area-under-curve and lift metrics. Explainable artificial intelligence represented with a permutation-based variable importance and a partial dependence profile help to discover the determinants of churn. We show that customers’ propensity to churn depends on: (i) payment value for the first order, number of items bought and shipping cost; (ii) categories of the products bought; (iii) demographic environment of the customer; and (iv) customer location. At the same time, customers’ propensity to churn is not influenced by: (i) population density in the customer’s area and division into rural and urban areas; (ii) quantitative review of the first purchase; and (iii) qualitative review summarised as a topic.
Impact of Inherited Genetic Variants on Critically Ill Septic Children

Sepsis remains an important source of morbidity and mortality in children, despite the development of standardized care. In the last decades, there has been an increased interest in genetic and genomic approaches to early recognition and development of treatments to manipulate the host inflammatory response. This review will present a summary of the normal host response to infection and progression to sepsis, followed by highlighting studies with a focus on gene association studies, epigenetics, and genome-wide expression profiling. The susceptibility (or outcome) of sepsis in children has been associated with several polymorphisms of genes broadly involved in inflammation, immunity, and coagulation. More recently, gene expression profiling has been focused on identifying novel biomarkers, pathways and therapeutic targets, and gene expression-based subclassification. Knowledge of a patient’s individual genotype may, in the not-too-remote future, be used to guide tailored treatment for sepsis. However, at present, the impact of genomics remains far from the bedside of critically ill children.
WOOD DENSITY IN SESSILE OAK (Quercus petraea Liebl.) : modelling of the within- and between-tree variability ; origin and non-destructive assessment of the « tree » effect ; interpretation of the developed model with anatomical traits.

The general objectives of the thesis are : i/ to develop a wood density model for Sessile oak (Quercus petraea Liebl.), which can be linked with diameter and height growth models, ii/ to test the model in contrasted conditions of climate, silviculture and site quality, iii/ to estimate the between-tree variability of wood density (i.e. variation due to the « tree » effect) by the means of non destructive measurements on standing trees and iv/ to investigate the anatomical modifications which produce within- and between-tree variations of wood density. After a literature review in a first chapter of relations linking wood density and some features of internal wood quality for Oak, the second chapter is devoted to the establishment of a wood density model for Sessile oak. The model is designed with data (microdensity at ring level as well as basic density at group of rings level) collected from 82 sessile oaks sampled in five French regions (Alsace, Lorraine, Orne et Sarthe, Allier, Loir-et-Cher). Two silvicultural schedules (coppice with standard and high forest) and three fertility classes were represented in each region. The model was developed using mixed model theory and takes into account the two main sources of variation identified in Sessile oak for wood density : i/ within-tree variations (i.e. variations along the radial and longitudinal axes of the tree) and ii/ between-tree variations. The proposed model is made up of : i/ a determinist part shared by every trees and ii/ a random part which structures the between-tree variations. In the work thesis the between-tree variations due to the so-called " tree
Semantic Conceptual Framework for Environmental Monitoring and Surveillance—A Case Study on Forest Fire Video Monitoring and Surveillance

This paper presents a semantic conceptual framework and definition of environmental monitoring and surveillance and demonstrates an ontology implementation of the framework. This framework is defined in a mathematical formulation and is built upon and focused on the notation of observation systems. This formulation is utilized in the analysis of the observation system. Three taxonomies are presented, namely, the taxonomy of (1) the sampling method, (2) the value format and (3) the functionality. The definition of concepts and their relationships in the conceptual framework clarifies the task of querying for information related to the state of the environment or conditions related to specific events. This framework aims to make the observation system more queryable and therefore more interactive for users or other systems. Using the proposed semantic conceptual framework, we derive definitions of the distinguished tasks of monitoring and surveillance. Monitoring is focused on the continuous assessment of an environment state and surveillance is focused on the collection of all data relevant for specific events. The proposed mathematical formulation is implemented in the format of the computer readable ontology. The presented ontology provides a general framework for the semantic retrieval of relevant environmental information. For the implementation of the proposed framework, we present a description of the Intelligent Forest Fire Video Monitoring and Surveillance system in Croatia. We present the implementation of the tasks of monitoring and surveillance in the application domain of forest fire management.
The Effect of HSV-1 Seropositivity on the Course of Pregnancy, Childbirth and the Condition of Newborns

The goal of this research was to evaluate seropositivity to HSV-1 among pregnant women and its effect on the course of pregnancy, childbirth and the condition of newborns. Methods: The serological status, socio-demographic characteristics, parity of pregnancy and childbirth and condition of newborns in women seronegative and seropositive to HSV-1 with recurrent infection and its latent course during pregnancy were analyzed. Newborns from these mothers made up the corresponding groups. Results: Low titers of IgG antibodies to HSV-1 in women in the first trimester of pregnancy are associated with threatened miscarriage, anemia in pregnancy and chronic placental insufficiency. High titers of IgG antibodies to HSV-1 in women in the second trimester of pregnancy are associated with late miscarriages and premature births, anemia in pregnancy, chronic placental insufficiency, labor anomalies, early neonatal complications (cerebral ischemia, respiratory distress syndrome) and localized skin rashes. Low titers of IgG antibodies to HSV-1 in women in the third trimester of pregnancy are associated with premature birth, anemia in pregnancy, chronic placental insufficiency, endometritis, complications of the early neonatal period and localized skin rashes. Conclusions: Our research showed that low or high titers of IgG antibodies to HSV-1, determined by the timing of recurrence of infection during pregnancy, are associated with a high incidence of somatic pathology and complications in pregnancy, childbirth and the neonatal period.
3D-imaging reveals conserved cerebrospinal fluid drainage via meningeal lymphatic vasculature in mice and humans

Meningeal lymphatic vessels (MLVs) contribute to waste product elimination and immune surveillance in brain tissues. MLVs were identified in the dorsal and caudo-basal regions of the dura mater, where they ensure the clearance of cerebrospinal fluid (CSF). Whether MLVs exist in the complex anterior part of the murine and human skull, and how they connect with the glymphatic system and extracranial lymphatic vasculature remained unclear. Here, we generated three-dimensional (3D) maps of MLV drainage by light-sheet fluorescence microscopy (LSFM) imaging of mouse whole-head preparations following fluorescent OVA-A555 tracer injections into the CSF. In humans, we performed real-time magnetic resonance vessel wall imaging (MR-VWI) after systemic gadobutrol injections. We observed a conserved 3D-anatomy of MLVs in mice and humans, and we discovered an extended anterior network around the dural cavernous sinus including multiple capillary beds and exit routes through the foramina of emissary veins. MR-VWI may provide a diagnostic tool for patients with CSF drainage defects and neurological diseases. Short abstract We established the 3D-anatomy of meningeal lymphatic vasculature and associated CSF drainage by postmortem light-sheet imaging in mice and by real-time magnetic resonance imaging in humans, demonstrating conserved lymphatic circuitries in contact with dural venous sinuses.
Effect of turbulent transport models and grid spacing on pans calculations of a lid-driven cavity

Effect of Turbulent Transport Models and Grid Spacing on PANS Calculations of a Lid-Driven Cavity. (August 2004) Aditya Murthi, B. En. , Amrita Institute of Technology and Science Chair of Advisory Committee: Dr. Sharath S. Girimaji The three-dimensional lid-driven cavity flow is investigated at Reynolds Number (Re)=10,000 for a wide range of spanwise aspect-ratios of 3:1:1,1:1:1 and 0.5:1:1, using the PANS (Partially Averaged Navier-Stokes) turbulence closure model. The PANS method is a variable resolution turbulence closure model, where the unresolvedto-total ratios of kinetic energy (fk) and dissipation (f2), serve as resolution control parameters. This study focuses on two main aspects of the PANS: first, the evaluation of Turbulent Transport models and second, the effect of grid spacing on accuracy of the numerical solution. The PANS calculations are tested against the LES and experimental results of Jordan (1994), in terms of both qualitative and quantitative quantities. The main conclusions are: (i) for a given fk value, the Zero-Transport (ZT) model is superior to the Maximum-Transport (MT) model for unresolved dissipation 2u, (ii) both the ZT and the MT models are adequate for unresolved kinetic energy Ku and, (iii) for a given grid size, the results depend heavily on grid spacing especially for larger fk values.
Novel Sequencing and Genomic Technologies Revolutionized Rice Genomic Study and Breeding

Rice is one of the most important food crops worldwide. Population growth and climate change posed great challenges for further rice production. In the past decade, we have witnessed an explosive development in novel sequencing and genomic technologies. These technologies have been widely applied in rice genomic study and improvement processes, and contributed greatly to increase the efficiency and accuracy of rice breeding. On the other hand, novel sequencing and genomic technologies also promote the shift of breeding schemes from conventional field selection processes to genomic assisted breeding. These technologies have revolutionized almost every aspect of rice study and breeding. Here, we systematically sorted out and reviewed the progress and advancements of sequencing and genomic technologies. We further discussed how these technologies were incorporated into rice breeding practices and helped accelerate the rice improvement process. Finally, we reflected on how to further utilize novel sequencing and genomic technologies in rice genetic improvement, as well as the future trends of advancement for these technologies. It can be expected that, as the sequencing and genomic technologies will develop much more quickly in the future, and be combined with novel bioinformatics tools, rice breeding will move forward into the genomic assisted era.
Condiciones laborales y satisfacción de los graduados del programa de Ortodoncia, Universidad Cooperativa de Colombia. Estudio Exploratorio

Introducción y objetivo: la ortodoncia se considera una especialidad clínica ejercida tradicionalmente en el marco de la práctica liberal independiente, sin embargo, los cambios en las dinámicas del mundo laboral, ameritan realizar monitoreo permanente de condiciones laborales de graduados de especialidades odontológicas. Describir las condiciones laborales y la satisfacción con el ejercicio profesional de los graduados del programa de ortodoncia, Universidad Cooperativa de Colombia, Sede Medellín. Materiales y métodos: estudio descriptivo transversal sobre el total de la población de graduados del programa. La información se recolectó a través de una encuesta. Se realizó análisis univariado para la descripción de la información y análisis bivariado para explorar asociaciones. Resultados: la frecuencia de respuesta fue del 65% y la totalidad de los participantes reportó un tiempo menor a 6 meses para su inserción laboral. Se estableció con mayor frecuencia contratación por prestación de servicios. En general, la satisfacción con el ejercicio profesional fue alta, sin embargo, un 39,4% reportó mediana o baja satisfacción con el tipo de contrato. El sexo se encontró asociado al número de horas laboradas semanalmente. Conclusiones: las condiciones de los graduados son favorables en ciertos aspectos, entre ellos, la inserción al mercado laboral en corto tiempo. Asimismo, los ingresos están en rango alto frente a los promedios del país, sin embargo, se requieren estudios que amplíen el análisis acerca de aspectos como el tipo de contratación, las horas laboradas y elementos de flexibilización laboral que pueden llevar a un deterioro progresivo del ejercicio profesional de los especialistas.