Miracle-dz/UniFAR-FTUs huggingface dataset:
Clinal Genetic Growth Variation Within Two Douglas-Fir Breeding Zones

- Twelve- and ten-year results ofprogeny tests of 1,275 wind-pollinated families ofcoastal Douglas-fir (Pseudo­ tsuga menziesii (Mirb.) Franco var. menziesii) are presented along with maps of clinal genetic variation within two breed­ ings zones. Data originate from the two oldest progressive tree-improvement cooperatives, called Vernonia and Molalla. In both, the top 20 percent of the families were 7 percent taller and 15 to 22 percent greater in volume than the mean family. Division of the parent group at the outset into sets of 50 families at Vernonia and 25 families at Molalla revealed that set means differed with origin within the breeding zone. Scattergrams of all parents in each cooperative showed that a downward shift of 1,000 feet in parent elevation, or a 10-mile horizontal shift to the east or north, should provide 5 percent more family height growth. Thus, there was evidence of considerable clinal geographic variation within breeding zones. Jsoheight patterns of clinal variation are complex and three­ dimensional, conforming to major topographic features in each cooperative area. ABSTRACT - The Washington State Department of Natural Resources is commercially thinning naturally established 40-year-old Douglas-fir (Pseudotsuga menziesii) stands which were once considered too small to be merchantable. Efficient, cost-effective thinning is accomplished by whole-tree chipping in the woods. The logging system includes a portable chipper, a chain-flail delimber, two rubber-tired grapple skidders, and three rubber-tired or tracked tree-to-tree feller-bunchers with accumulators. This system provides total utilization of the harvested material. An average of 100 to 125 green tons of· pulp chips with less than 7-percent bark can be produced in an eight-hour shift. Approximately 1,000 stems per acre, averaging 4 inches in diameter at breast height, are removed to leave 200 of the best trees. This stocking gives adequate growing space and provides operational maneuverability. The feller-buncher operators are trained to select trees by follow­ ing rules that describe leave trees. Stand damage can be kept within acceptable limits, preferably under 5 percent of the leave trees, by requiring prelocated skid trail systems and rub trees. Successful tree selection and avoidance of stand dam­
Framework for Opinion Access Service To Make Smart Business Decisions - Twitter as a Case Study

: Twitter has grown to be a foremost influence in our daily lives. Twitter has emerged from online short communication network into an increasingly useful platform for the teenagers, marketers, researchers, scholars and many more. It is now on the apex of its colossal spurt. It has become a popular micro blogging site where people can share their experiences, views, thoughts and events. This voluminous data of twitter shared by people helps in making decisions and analyze the opinions of them. Sentiment Analysis, a part of Opinion analysis help in finding the current status of particular product based on which the marketers can improve the business quality i.e. public perception can also be known by tracking their interests thus help in framing a useful pace to predict future of a product. The paper focuses on Analysis of data from the SNS i.e. twitter and also details simple steps to increase the proficiency of the business using Data Mining Techniques. Survey on many research papers is carried out and designed the framework. This paper acts as the stepping stone for the efficient development of twitter mining tools. Further it helps in implementing improved algorithm for the betterment of customers’ insight on/towards product.
Testing Association of a Pathway with a Clinical Variable

This paper presents a global test to be used for the analysis of microarray data. Using this test it can be determined whether the global expression pattern of a group of genes is signiﬁcantly related to some clinical outcome of interest. Groups of genes may be any size from a single gene to all genes on the chip (e.g. known pathways, speciﬁc areas of the genome or clusters from a cluster analysis). The test allows groups of genes of different size to be compared, because the test gives one p-value for the group, not a p-value for each gene. Researchers can use the test to investigate hypotheses based on theory or past research or to mine gene ontology databases for interesting pathways. Multiple testing problems do not occur unless many groups are tested. Special attention is given to visualizations of the test result, focussing on the associations between samples and showing the impact of individual genes on the test result. An R-package GlobalTest is available from http://www.bioconductor. org.
Machine Learning: A Quantum Perspective

Recently, increased availability of the data has led to advances in the field of machine learning. Despite of the growth in the domain of machine learning, the proximity to the physical limits of chip fabrication in classical computing is motivating researchers to explore the properties of quantum computing. Since quantum computers leverages the properties of quantum mechanics, it carries the ability to surpass classical computers in machine learning tasks. The study in this paper contributes in enabling researchers to understand how quantum computers can bring a paradigm shift in the field of machine learning. This paper addresses the concepts of quantum computing which influences machine learning in a quan- tum world. It also states the speedup observed in different machine learning algorithms when executed on quantum computers. The paper towards the end advocates the use of quantum application software and throw light on the existing challenges faced by quantum computers in the current scenario.
ROLE OF ASC IN HELICOBACTER PYLORI INFECTION

Apoptosis associated speck-like protein containing a C-terminal caspase recruitment domain (ASC) is an adaptor molecule activating caspase-1 that stimulates pro-IL-1 β and pro-IL-18, two proinflammatory cytokines with critical functions in host defense against a variety of pathogens. In the present study, we investigated the role of ASC in the host defense against Helicobacter pylori utilizing ASC-deficient mice. Mice were orally inoculated with H. pylori ; bacterial load, degree of gastritis, and mucosal levels of inflammatory cytokines were analyzed and compared with those obtained from wild-type mice. We found more prominent H. pylori colonization in ASC-deficient mice, as revealed by colony-forming unit (CFU) counts. Both groups of mice developed gastritis; however, ASC-deficient mice showed significant attenuation of inflammation despite high H. pylori colonization. ELISA and quantitative RT-PCR analysis revealed complete suppression of IL-18 and substantial reduction of IFN- γ expression, respectively, in ASC-deficient mice without apparent upregulation of other cytokines including IL-10 and TNF- α . These results as a whole indicate that ASC exerts considerable influence on the host defense acting through IL-18 and subsequent IFN- γ production, which in turn contributes to continuous chronic inflammatory response and consequent reduction of H. pylori colonization.
A systematic review on the prevalence and management of PCOS through dietary modifications

The objective of this study is to find out the widespread prevalence of PCOS across the world along with its causes, people who all are affected and results of this disease. PCOS is most severe in Asian and American females; both are found to be the most affected ones followed by Caucasian ones, which are further followed by the African ones. So, it’s necessary to know about the disease, its pathogenicity, symptoms and causes in females of different origin and what can be the preventive measures like dietary modifications and controlling other health conditions and other factors so as to avoid the disease or at least lowering the impact of the disease. Avoidance and early curing of the disease is the main motto of the research. Common symptoms of the disease include marked decrease in the female characters. Other symptoms like irregular or no menstruation, excess hairs on face, chest, stomach, thumbs, or toes, decrease in breast size, hair loss, acne, depression, weight gain, pelvic pain and infertility are also checked. Most commonly, it affects the females of reproductive age. This is one of the most widespread diseases across the world and if left untreated, may result in infertility and even uterine cancer and hence this study is done. This study focuses on the prevalence, management and dietary modifications of the disease.
Clinical features of acute pancreatitis in the elderly

高齢者急性膵炎の特徴を明らかにするために，急性膵炎患者を，高齢者群30例と非高齢者群64例とに分けて比較検討した．性別では高齢者で女性に多く認められた（60%）．成因として，高齢者では，胆石性（54%），特発性（24%）が多く認められた．血液検査では，炎症所見において，白血球が，有意に低値を示した（p＜0.05）．摂食開始時期は，高齢者が有意に遅かった．入院期間は有意に高齢者ほど長くなることが示された．体表面積あたりの，急性期に必要とした初期治療に要した輸液量を検討すると，高齢者は2,012±102ml/m2/dayで，非高齢者1,722±318ml/m2/dayに対し，必要輸液量が有意に多く必要となることが示された．高齢者の急性膵炎治療では，入院期間が延長する傾向にあり，栄養状態の変化に留意する必要がある．特に必要輸液量が多くなることに留意すべきである．
De novo genome assembly of plant-associated Rhodococcus qingshengii (RL1) isolated from Eruca sativa Mill. showing plant growth promoting properties

Rhodococcus qingshengii RL1 was isolated from surface-sterilized leaves of Eruca sativa Mill. and shows plant growth promoting (PGP) properties. The de novo genome assembly consists of one chromosome with 6.253. 838 bp and two plasmids with 144.038 bp and 448.745 bp. Many genes could be identified reflecting its PGP potential. The genus Rhodococcus belongs to the phylum Actinobacteria and includes aerobic, Gram-positive, nonsporulating bacteria isolated from a broad variety of environments (1–3). Some of these bacteria have large genomes (> 5 Mb) with high GC content. Their ability to degrade a large spectrum of environmentally problematic compounds (2, 4) or perform quorum quenching (5) makes them suitable for bioremediation or agricultural applications. RL1 was isolated from surface-sterilized leaves of Eruca sativa Mill. The de novo assembly of the RL1 genome showed highest similarity of > 99% sequence identity with over 90% of the Rhodococcus qingshengii djl-6 T genome, and the 16S rDNA of RL1 was 99,9% identical with djl-6 T . In a 16S rDNA based phylogenetic neighbor-joining tree (6) calculated with ARB (7) RL1 was placed within a cluster (bootstrap support 99%) consisting of Rhodococcus erythropolis T , Rhodococcus qingshengii djl-6 T , Rhodococcus degradans CCM 4446 T and Rhodococcus baikonurensis T Further phylogenetic analysis of the gyrB gene verified the taxonomic of RL1 as Rhodococcus qingshengii (data ), antibiotics production, biofilm formation, lipopolysaccharides production, multidrug resistance, microbe-associated molecular patterns (MAMPs), heavy metal tolerance and reactive oxygen species resistance.
Integral charge SUSY in Strong nuclear gravity

Till today there is no reason for the question: why there exists 6 individual quarks? Till today no experiment reported a free fractional charge quark. Authors humble opinion is nuclear charge (either positive or negative) constitutes 6 different flavors and each flavor holds certain mass. charged flavor can be called as a quark. It is neither a fermion nor a boson. A fermion is a container for different charges, a charge is a container for different flavors and each flavor is a container for certain matter. If charged matter rests in a fermionic container it is a fermion and if charged matter rests in a bosonic container it is a boson. The fundamental questions to be answered are : what is a charge? why and how opposite charges attracts each other? why and how there exists a fermion? and why and how there exists a boson? Here interesting thing is that if 6 flavors are existing with 6 different masses then a single charge can have one or two or more flavors simultaneously. Since charge is a common property, mass of the multiple flavor charge seems to be the geometric mean of the mass of each flavor. If charge with flavor is called as a quark then charge with multi flavors can be called as a hybrid quark. Hybrid quark generates a multi flavor baryon. It is a property of strong interaction space time charge. This is just like different tastes or different smells of matter. Important consequence of this idea is thatfor generating a baryon there is no need to couple 3 fractional charge quarks. In integral charge quark system, if Qf and Qb are the rest masses of quark fermion and
Preprocessing Methods for Enhancing Micro aneurysm in Fundus Images

- Diabetic retinopathy is an eye disease caused due to abnormalities in blood vessels. Detection of micro aneurysms in fundus retinal images is the early stage of diagnosis Diabetic Retinopathy (DR). Micro aneurysm is tiny aneurysm or swelling in side of blood vessels. Image processing plays vital role in automatic detection of DR. The initial stage of this, is Preprocessing. Therefore in this paper we are going to introduce preprocessing techniques which are useful for feature extraction for detection of microanuerysm in retinal images.
Real-Time Simulation of Thin Rod

This paper proposes a real-time simulation technique for thin rods undergoing large rotational deformation. Rods are thin objects such as ropes and hairs that can be abstracted as one-dimensional structures. Development of a real-time physical model that can produce visually convincing animation of thin rods has been a challenging problem in computer graphics. We adopt continuum mechanics to formulate the governing equation, and develop a modal warping technique for rods to integrate the governing equation in real-time; This is a novel extension of the previous modal warping techniques developed for solids and shells. Experimental results show that the proposed method runs in real-time even for large meshes and it can simulate large bending and/or twisting deformations.
ERK - Proliferation by Enhancing MAPK Generation: Coupling Differentiation and IL-2 Requirement for Human Plasma Cell

Mature B cell differentiation involves a well-established transcription factor cascade. However, the temporal dynamics of cell signaling pathways regulating transcription factor network and coordinating cell proliferation and differentiation remain poorly deﬁned. To gain insight into the molecular processes and extrinsic cues required for B cell differentiation, we set up a controlled primary culture system to differentiate human naive B cells into plasma cells (PCs). We identiﬁed T cell-produced IL-2 to be crit-ically involved in ERK1/2-triggered PC differentiation. IL-2 drove activated B cell differentiation toward PC independently of its proliferation and survival functions. Indeed, IL-2 potentiated ERK activation and subsequent BACH2 and IRF8 downregulation, sustaining BLIMP1 expression, the master regulator for PC differentiation. Inhibition of the MAPK–ERK pathway, unlike STAT5 signaling, impaired IL-2–induced PC differentiation and rescued the expression proﬁle of BACH2 and IRF8 . These results identify IL-2 as a crucial early input in mature B cell fate commitment. The Journal of Immunology , 2012, 189: 000–000.
Evolutionarily conserved regulation of hypocretin neuron specification by Lhx9

Loss of neurons that express the neuropeptide hypocretin (Hcrt) has been implicated in narcolepsy, a debilitating disordercharacterized by excessive daytime sleepiness and cataplexy. Cell replacement therapy, using Hcrt-expressing neurons generated in vitro , is a potentially useful therapeutic approach, but factors sufficient to specify Hcrt neurons are unknown. Using zebrafish as a high-throughput system to screen for factors that can specify Hcrt neurons in vivo , we identified the LIM homeobox transcription factor Lhx9 as necessary and sufficient to specify Hcrt neurons. We found that Lhx9 can directly induce hcrt expression and we identified two potential Lhx9 binding sites in the zebrafish hcrt promoter. Akin to its function in zebrafish, we found that Lhx9 is sufficient to specify Hcrt -expressing neurons in the developing mouse hypothalamus. Our results elucidate an evolutionarily conserved role for Lhx9 in Hcrt neuron specification that improves our understanding of Hcrt neuron development.
The Main Conjecture for Near-MDS Codes

HAL is a multi-disciplinary open access archive for the deposit and dissemination of scientific research documents, whether they are published or not. The documents may come from teaching and research institutions in France or abroad, or from public or private research centers. L’archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d’enseignement et de recherche français ou étrangers, des laboratoires publics ou privés. The Main Conjecture for Near-MDS Codes Ivan Landjev, Assia Rousseva
Seasonal Branch Nutrient Dynamics in Two Mediterranean Woody Shrubs with Contrasted Phenology

d Background and aims Mediterranean woody plants have a wide variety of phenological strategies. Some authors have classiﬁed the Mediterranean phanaerophytes into two broad phenological categories: phenophase-overlappers (that overlap resource-demanding activities in a short period of the year) and phenophase-sequencers (that protract resource-demanding activities throughout the year). In this work the impact of both phenological strategies on leaf nutrient accumulation and retranslocation dynamics at the level of leaves and branches was evaluated. Phenophase-overlappers were expected to accumulate nutrients in leaves throughout most of the year and withdraw them efﬁciently in a short period. Phenophase-sequencers were expected to withdraw nutrients progressively throughout the year, without long accumulation periods. d Methods To test this hypothesis, variations in phenology and leaf NPK in the crown of a phenophase-overlap- per Cistus laurifolius and a phenophase-sequencer Bupleurum fruticosum were monitored monthly during 2 years. d Key Results Changes in nutrient concentration at the leaf level were not clearly related with the different phenologies. Nitrogen and phosphorous resorption efﬁciencies were lower in the phenophase-overlapper, and accumulation–retranslocation seasonality was similar in both species. Changes in the branch nutrient pool agreed with the hypothesis that the phenophase-overlapper accumulated nutrients from summer until the bud burst of the following spring, recovering a large nutrient pool during massive leaf shedding. The phenophase-sequencer did not accumulate nutrients from autumn until early spring, achieving lower nutrient recovery during spring leaf shedding. d Conclusions It is that phenological demands inﬂuence branch nutrient cycling. This effect is easier to detect by assessing changes in the branch nutrient pool rather than changes in the leaf nutrient concentration. Annals of Botany Company
A Low-cost & Realtime Motion Capture System

Traditional marker-based motion capture requires excessive and specialized equipment, hindering accessibility and wider adoption. In this work, we demonstrate such a system but rely on a very sparse set of low-cost consumer-grade sensors. Our system exploits a data-driven backend to infer the captured subject's joint positions from noisy marker estimates in real-time. In addition to reduced costs and portability, its inherent denoising nature allows for quicker captures by alleviating the need for precise marker placement and post-processing, making it suitable for interactive virtual reality applications.
Evaluating the Impact of Bilingual Lexical Resources on Cross-lingual Sentiment Projection in the Pharmaceutical Domain

Rolling out text analytics applications or individual components thereof to multiple input languages of interest requires scalable work-ﬂows and architectures that do not rely on manual annotation efforts or language-speciﬁc re-engineering per target language. These scalability challenges aggravate even further if specialized technical domains are targeted in multiple languages. In recent work, it has been shown that cross-lingual projection of sentiment models in deep learning frameworks based on bilingual sentiment embed-dings (BLSE) is feasible without any annotated data in the target language, capitalizing on monolingual embeddings and a bilingual translation dictionary only (Barnes et al., 2018a). We use their framework and apply it to multilingual text analytics problems in the pharmaceutical domain in order to (i) investigate under which conditions the BLSE approach scales to technical domains as well, and (ii) assess the impact of different conﬁg-urations of underlying lexical resources. For the language pair English/Spanish, our ﬁndings corroborate the strength of cross-lingual projection approaches such as BLSE in technical scenarios, given the availability of bilingual resources that provide broad lexical coverage, on the one hand, and complementary domain-and task-speciﬁc knowledge, on the other.
Urban Heat Island High Local Water-Vapor Feedback Estimates Requiring Albedo Management 1

In this paper, we analyze warming data on Urban Heat Islands (UHI) in dry versus humid environments to estimate 4 local water-vapor feedback from city growth. We find looking at such data and comparing rural to urban areas, UHI 5 local water-vapor feedback is about 3 W/m 2 / o K to a maximum of 4 W/m 2 / o K. Relative to global climate feedback 6 estimates of about 2 W/m 2 / o K, this is a factor of 1.5 to 2 times higher. This UHI effect is observed during daytime 7 hours. Water-vapor feedback is known to be one of the most important in our climate system and thought that it can 8 double the direct known forcing and is found here to be an even stronger UHI local effect. We suspect with city 9 growth there is a loss of natural convection cooling and an increase in dome heat/humidity from UHI impermeable 10 surfaces since warm air holds more water-vapor creating a local greenhouse gas (GHG). These are key contributors 11 to local water-vapor feedback raising local temperatures in humid cities. An optimum way to mitigate this effect is 12 with UHI albedo management. We suggest that this warming effect can be an important factor in UHI global 13 warming contributions and should be mitigated.
) Biomarker clustering of colorectal cancer data to complement clinical classification. In: Federated

— In this paper, we describe a dataset relating to cellular and physical conditions of patients who are operated upon to remove colorectal tumours. This data provides a unique insight into immunological status at the point of tumour removal, tumour classification and post-operative survival. Attempts are made to cluster this dataset and important subsets of it in an effort to characterize the data and validate existing standards for tumour classification. It is apparent from optimal clustering that existing tumour classification is largely unrelated to immunological factors within a patient and that there may be scope for re-evaluating treatment options and survival estimates based on a combination of tumour physiology and patient histochemistry.