Miracle-dz/UniFAR-FTUs huggingface dataset:
Implementation of Problem-based Learning – Flipped Classroom Model in Chemistry and Its Effect on Scientific Literacy

This study aims to determine the effect of the problem-based learning–flipped classroom model and critical-thinking skills toward students' scientific literacy on the topic of reaction rates. The implementation of the problem-based learning–flipped classroom model is considered appropriate for developing students' critical–thinking skills and scientific literacy. The learning time in the classroom becomes more effective and through a problem–solving process, the students can develop critical-thinking skills, and it is hoped that students' scientific literacy can also develop. This research used the true experiment method with two-way ANOVA research design (2x2 treatment by level design). Seventy two students at one of the senior high schools in Jakarta become samples. Data collection techniques in this study are through tests of critical-thinking skills and scientific literacy tests. The results showed that the model of problem-based learning-flipped classroom influenced student's scientific literacy on chemical reaction rate. Each model gives different effect towards the students’ scientific literacy, if it is applied to students who have different critical-thinking skills. The model of problem-based learning-flipped classroom is more effectively applied to the students who have high critical-thinking skills.
Investigating the Presence of Plasmodium falciparum Chloroquine Resistant Transporter (Pfcrt) Drug-resistance Alleles in Some Northern Nigerian States

This study was designed to investigate the presence of Pfcrt drug- resistance alleles (CQ resistant biomarker) and attempted to analyse the outcome in some states of northern Nigeria. A total of four hundred and thirteen (413) Plasmodium falciparum positive blood samples were collected from Kaduna, Jigawa, Katsina and Kebbi states during the period of April-August 2013. The samples were genotyped at codon 76 using specific primers for Pfcrt gene. The data was analysed using Chi-square to determine significance association. Four hundred and thirteen (413) P. falciparum positive samples were genotyped at codon 76 of pfcrt gene. Sixty eight 68(16.5%) samples contained single K76 (Chloroquine sensitive) alleles, 49(11.9%) contained 76T, while 16(3.9%) contained mixed K76T alleles. K76 alleles were highest in Kaduna state 17(32.1%) and lowest in Kebbi state 10(7.4%), 76T was highest in Jigawa state 11 (25.6%) and lowest in Kebbi state 7(5.2%) while K76T was highest in Jigawa state 5(11.5%) and lowest in Kebbi state 2(1.5%) with significant difference between the states P<0.05. K76 was higher among females 43(17.6%), 76T was also higher females 30(12.2%) while K76T was higher among males 7 (4.2%). K76 was higher among age group of 16-25 years 17(22.4%) and least among 26-40years age group 13 (13.5%). 76T was also higher among 26-40 years age group 17(17.7%) and least among age group >40 years 1(2.0%) and K76T was higher among age group 16-25 years 6(7.9%) and least in >40 years of age 1(2.0%) with high significant difference P<0.05 between the age groups. The results of this study genetically confirms the use of CQ for malaria treatment in the area and attributed the varied distribution across the states, to high irrigation activities, self medication leading to dosage non compliance and improper diagnosis due to use of low sensitive RDT in most government hospitals. The need for enlightenment of the populace cannot over emphasize.
Exploring factors influencing on organizational repurchases intention in B2B tourism context

Article history: Received: August 18 2019 Received in revised format: August 18 2019 Accepted: September 23, 2019 Available online: September 23, 2019 The relationship between perceived values; customer satisfaction and customer repurchase intention of organizations toward tour choice in Ho Chi Minh City (HCMC) was defined in this study. In addition, this study also identified the impacts of the five independent variables of tangibles, assurance, empathy, reliability and responsiveness and the intervening variables of perceived value and customer satisfaction on repurchase intention. Quantitative research was conducted by questionnaire with 300 middle and small organizations in HCMC, with variety of statistical techniques; including factor analysis, multiple regression analyses and path analysis to find the relationship between independent and dependent variables. Based on the results, the study suggests the fact that a higher perceived value would lead to a higher customer satisfaction. When consumers feel satisfied with services, they feel the choice was correct, which increases the customer’s confidence and intention to repurchase the service in future. © 2020 by the authors; licensee Growing Science, Canada
A Method for Designing Domain-Specific Document Retrieval Systems using Semantic Indexing

Using domain knowledge and semantics to con-duct e‡ective document retrieval has attracted great attention from researchers in many di‡erent communities. Ultilizing that approach, we presents the method for designing domain-speciyc document retrieval systems, which manages semantic information related to document content and supports se-mantic processing in search. ⁄e proposed method integrates components such as an ontology describing domain knowl-edge, a database of document repository, semantic represen-tations for documents; and advanced search techniques based on measuring semantic similarity. In this article, a model of domain knowledge for various information retrieval tasks, called ⁄e Classed Keyphrase based Ontology (CK-ONTO), will be presented in details. We also present graph-based models for representing documents together measures for evaluating the semantic relevance for usage in searching. ⁄e above methodology has been used in designing many real-world applications such as the Job-posting retrieval system. Evaluation with real-world inspired dataset, our methods showed noticeable improvements over traditional retrieval solutions.
Superabsorbent

Superabsorbent hydrogel (SAH) is a cross-linked polyelectrolyte polymer that has the capability to absorb a lot of water by keeping it in a three-dimensional (3D) structure. The network’s structure of SAH has the high elasticity that gives the ability of pores to expand in an aqueous media into up to 150–1500 times their own size in a dry state. The size of pores is the major factor that controls the swelling degree of the hydrogel. In contrast, the swelling degree is related to cross-linked density and the number of polarizable functional groups that immobilize on the polymer backbone. The hydrogels could be made by radical-initiated polymerization of hydrophilic monomers, and/or linear polymers dissolve in an aqueous solution. Free radical polymerization of the hydrogel can be done physically or chemically. Advantages and disadvantages of each method will be elabo-rated in this chapter. The advances in radiation cross-linking methods for the hydrogel preparation are particularly addressed besides other different techniques, e.g., (freezing/ thawing and chemical initiation). This chapter will review the preparation methods of superabsorbent hydrogels from synthetic and natural hydrophilic polymers with other new phases such as wax, gum, and rubber. Methods to characterize these hydrogels and their proposed applications (internal curing agent for cement, agricultural proposal, biomedical proposal, and environmental proposal) are also reviewed.
Men's Perception about Cancer Prostate at Main University Hospital Assuit Governorate

Background: Cancer Prostate has been a major public health issue worldwide. The men are often diagnosed in the late stages of the disease. Increase the level of perceptions among men helps to detect and diagnostic measures early. Aim of the study: To assess perception of men's about Cancer Prostate at Main University Hospital Assiut Governorate. Design: Descriptive research design. A convenient sample was used, the sample were included 1500 patients up to forty years who attendance in outpatients clinics, within 6 months. The study included two tools; the first tool was interview sheet to assess (a) demographic data (b) Men's perception about cancer Prostate , and the second tool was Respondents' of prostate screening testing scale . Results: More than three-fifths of the participants had low perception of cancer Prostate. Conclusion: There was a positive correlation between perceptions, & responding screening to Cancer Prostate. Recommendations: Health education programs to increase the knowledge of people regarding cancer Prostate and the importance of periodical examinations of cancer Prostate over age forty for early detections and health promotion in all its aspect.
Salient Genetic and Proteomic Pathways in Glaucoma

Glaucoma, the second leading cause of blindness worldwide is a neurodegenerative disease, with or without elevated ocular pressure, exhibiting several different phenotypic presentations, which result in progressive visual field loss after compromise of retinal ganglion cells and their axons to the optic nerve and brain. Predominant clinical glaucoma types are primary open angle, POAG, angle closure, and congenital; secondary glaucomas are: psuedoexfoliaiton, pigmentary, neovascular, traumatic, iridoendothelial, and uveitic glaucoma. In each of these types of glaucoma, genetic, epigenetic, proteomic, environmental, and mechanical forces may converge as well to cause or advance the disease. Alternatively, but not necessarily in an independent fashion, stress related pathways of oxidative stress, inflammation, infection, trauma, immune reaction, neuro-degeneration and mutant genomic products can produce deleterious misfolded proteins, antibodies, and aggregate deposits in the trabecular meshwork, TM, raise the intraocular pressure and result in optic nerve damage and loss of vision. Examining the interplay of these stress pathways with genetic, epigenetic, proteomic, environmental and mechanical forces to gain some understanding of molecular causes of glaucoma is the goal of this paper. Pseudoexfoliaiton syndrome; REST: Repression element silencing transcription factor; Retinal Ganglion Cell; Rho Kinase protein kinase modifying cell shape, size and adhesion; SC: Schlemm’s Canal; SPARC: Secreted Protein Acidic Rich in cysteine, binds to ECM proteins and regulate matrix metalloproteinase expression; SMAD: ‘Small Mothers against decapentaplegic homolog’ literally but actually transcription factor which mediates TGF beta transduction or simply helps transfer cytoplasmic signals to nucleus to activate molecules like MAP or Rho kinase; TEK: Receptor tyrosine kinase; TGF: Beta transforming growth factor beta (signalling differentiation, proliferation, chemotaxis and fibrosis); TIMP 3: Tissue inhibitor of metalloproteinase; TLR4: Toll like receptor 4; TM: Trabecular meshwork; TNF: Tumour necrosis factor; TNFR: Tumour necrosis factor receptor; UPR: Unfolded protein response; VCAM1: Vascular adhesion protein; Visual misfolded
Comprehensive bioinformatics analyses identified Homeobox B9 as a potential prognostic biomarker and therapeutic target for gastric cancer.

Background The Homeobox B (HOXB) family promotes tumor progression, but the mechanism of its action in gastric cancer (GC) is unclear. We sought to identify the HOXB family members that are critical to the prognosis of GC patients. Methods The Oncomine, Gene Expression Profiling Interactive Analysis (GEPIA), cBioPortal, UALCAN, Kaplan-Meier plotter, and the GeneMANIA databases were used to analyze the messenger RNA (mRNA) expression levels, prognostic value, and gene-gene interaction network of the HOXB9 family members in GC. The expression of HOXB9 in GC and its relationship with various clinicopathological parameters and the prognosis of patients were verified by immunohistochemistry. Results The expression of HOXB3, HOXB5, HOXB6, HOXB7, HOXB9, and HOXB13 mRNA was significantly upregulated in GC. There was a significant correlation between the upregulation of HOXB3, HOXB5, and HOXB9 mRNA and a low overall survival (OS) rate. The high expression of HOXB7, HOXB9, and HOXB13 mRNA was closely correlated to tumor grade and stage. HOXB9 was the HOXB family member most closely related to the occurrence and development of GC. A further analysis showed that HOXB9 might be involved in deoxyribonucleic acid repair and division regulation. A validation study showed that the advanced cancer group had a higher level of HOXB9 expression than the early cancer group. The high expression of HOXB9 in gastric tissue plays an important role in the survival and prognosis of GC patients. Conclusions HOXB family members have different degrees of abnormal expression in GC. High HOXB9 expression in GC tissues was significantly correlated with a worse prognosis. Thus, HOXB9 is a potential novel biomarker and therapeutic target for GC.
Molecular typing of lung adenocarcinoma with computed tomography and CT image-based radiomics: a narrative review of research progress and prospects

Objective The purpose of this paper was to perform a narrative review of current research evidence on conventional computed tomography (CT) imaging features and CT image-based radiomic features for predicting gene mutations in lung adenocarcinoma and discuss how to translate the research findings to guide future practice. Background Lung cancer, especially lung adenocarcinoma, is the leading cause of cancer-related deaths. With advances in the diagnosis and treatment of lung adenocarcinoma with the emergence of molecular testing, the prediction of oncogenes and even drug resistance gene mutations have become key to individualized and precise clinical treatment in order to prolong survival and improve quality of life. The progress of imageological examination includes the development of CT and radiomics are promising quantitative methods for predicting different gene mutations in lung adenocarcinoma, especially common mutations, such as epidermal growth factor receptor (EGFR) mutation, anaplastic lymphoma kinase (ALK) mutation and Kirsten rat sarcoma viral oncogene (KRAS) mutation. Methods The PubMed electronic database was searched along with a set of terms specific to lung adenocarcinoma, radiomics (including texture analysis), CT, computed tomography, EGFR, ALK, KRAS, rearranging transfection (RET) rearrangement and c-ros oncogene 1 (ROS-1), v-raf murine sarcoma viral oncogene homolog B1 (BRAF), and human epidermal growth factor receptor 2 (HER2) mutations et al. This review has been reported in compliance with the Narrative Review checklist guidelines. From each full-text article, information was extracted regarding a set of terms above. Conclusions Research on the application of conventional CT features and CT image-based radiomic features for predicting the gene mutation status of lung adenocarcinoma is still in a preliminary stage. Noninvasively determination of mutation status in lung adenocarcinoma before targeted therapy with conventional CT features and CT image-based radiomic features remains both hopes and challenges. Before radiomics could be applied in clinical practice, more work needs to be done.
THE EFFECT OF ROTOR ROTATION SPEED ON DECREASED LABORATORY LIQUID WASTE POLLUTING PARAMETERS

<span id="docs-internal-guid-ee22e381-7fff-07aa-8160-5bce2ec61810"><span>aboratory wastewater is produced through laboratory activities. Laboratory wastewater can have a large impact on the environment if it is not processed before being discharged into the water body. Laboratory waste treatment can be carried out using suspended growth technology to reduce pollutant loads, especially Biological Oxygen Demand (BOD</span><span><span>5</span></span><span>) and Chemical Oxygen Demand (COD). </span><span>Aims:</span><span> This study aims to treat wastewater produced by the activity of laboratory using suspended growth technology. </span><span>Methodology and Results:</span><span> This research was conducted by finding the most efficient rotor rotation in degrading the load of BOD5 and COD pollutants. The reactor used is a Mixed Flow Reactor type reactor made of acrylic material with a thickness of 5.5 mm. The reactor is arranged into three series with the same sampling time and different rotor turns that expressed in rotors per minute (rpm). The reactor series consists of Reactor I with 50 rpm rotor rotation speed, 100 rpm Reactor II and 150 rpm Reactor III. Processing is carried out using 8 hours of detention time and variation of sampling time every 8 hours. </span><span>Conclusion, significant and impact study:</span><span> From the results of the study obtained the highest level of effectiveness of reducing pollutant load on processing using 150 rpm rotor rotation and 40 hours sampling time which is 94.6% for BOD</span><span><span>5 </span></span><span>parameters and 94.4% for COD parameters. </span></span>
Running Head Right-hand : Management of Conditions Caused by MDMA Running Head Left-hand :

In chapter fifteen, ‘Clinical and medical management of conditions caused by MDMA or “Ecstasy”’, Andrew Parrott provides an overview of the evolution of the MDMA market over the years, which has become increasingly more complex and multifaceted with the introduction of products containing very high doses of MDMA or substances passed as MDMA but actually containing a series of different products. A detailed analysis of incidences, dangers, and available treatments has been provided as well as a review of causes of death and prevention strategies. Andrew Parrott will also discuss the clinical presentation of toxicity and clinical management strategies for clinicians. Running Head Right-hand: Management of Conditions Caused by MDMA Running Head Left-hand: Andrew C. Parrott
Development and field testing of an online instrument for measuring the real-time oxidative potential of ambient particulate matter based on dithiothreitol assay

Abstract. We developed an online instrument for measuring the oxidative potential (OP) of ambient particulate matter (PM) using the dithiothreitol (DTT) assay. The instrument uses a mist chamber (MC) to continuously collect the ambient PM2.5 in water, and then determines its DTT activity using an automated syringe pump system. The instrument was deployed at an urban site in the University of Illinois campus, and its field performance was evaluated by comparing the results with the offline DTT activity measurements of simultaneously collected PM-laden filters. The online DTT activity measurements correlated well with the offline measurements but were higher than both methanol (slope =1.08, R2=0.93) and Milli-Q water (slope =1.86, R2=0.86) extracts of the PM filters, indicating a better efficiency of the MC for collecting the water-insoluble fraction of PM. The hourly measurements of ambient PM2.5 OP were obtained by running the online instrument intermittently for 50 days with minimal manual assistance. The daytime DTT activity levels were generally higher than at night. However, a 4-fold increase in the hourly averaged activity was observed on the night of 4 July (Independence Day fireworks display). The diurnal profile of the hourly averaged OP during weekdays showed a bimodal trend, with a sharp peak in the morning (around 07:00 LT), followed by a broader afternoon peak which plateaus around 14:00 LT and starts subsiding at night (around 19:00 LT). To investigate the association of the diurnal profile of DTT activity with the emission sources at the site, we collected time-segregated composite PM filter samples in four different time periods of the day (morning, 07:00–10:00 LT; afternoon, 10:00–15:00 LT; evening, 15:00–19:00 LT; and night, 19:00–07:00 LT) and determined the diurnal variations in the redox active components (i.e., water-soluble Cu, Fe, Mn, organic carbon, elemental carbon, and water-soluble organic carbon). Based on this comparison, we attributed the daytime OP of ambient PM2.5 to the vehicular (both exhaust and non-exhaust) emissions and resuspended dust, whereas secondary photochemical transformation of primary emissions appear to enhance the OP of PM during the afternoon and evening period.
MANEJO ODONTOLÓGICO EM PACIENTE COM AMILOIDOSE SUBMETIDO A TRANSPLANTE AUTÓLOGO DE CÉLULAS-TRONCO HEMATOPOIÉTICAS – RELATO DE CASO

A amiloidose é caracterizada pela deposição extracelular de uma proteína fibrilar insolúvel de cadeia pesada em órgãos e tecidos e pode ser classificada como primária ou secundária. Relato de Caso: Um paciente do gênero masculino, 62 anos, apresentou queixa de dor lombar acompanhada por macroglossia. A biópsia de língua confirmou o diagnóstico de amiloidose. O tratamento instituído foi de transplante autólogo de células-tronco hematopoéticas. O exame físico intraoral no período do transplante mostrou macroglossia, lábios e mucosa desidratados, sem lesões ulceradas em toda a mucosa oral e linfadenopatia submandibular. Protocolo de higiene oral foi instituído, baseado em uso de escova extra-macia e creme dental à base de clorexidina, associado a bochechos, HPA-Lanolina para a hidratação dos lábios e hidratante gel para mucosa oral. Laserterapia de baixa potência para mucosite oral teve início em D 0 até D + 11. Escala Visual Analógica foi utilizada para quantificar o escore de dor / desconforto da língua e orofaringe. A pontuação descrita pelo paciente na língua antes da laserterapia (variação de 0-6) e depois da laserterapia (variação de 0-3). O paciente atingiu o maior grau de mucosite oral (Grau 1 - OMS). Conclusães: O diagnóstico de amiloidose com manifestação bucal e a aplicação do protocolo de higiene bucal na prevenção de mucosite oral durante o transplante foram eficazes no controle e redução das manifestações bucais durante o transplante e tem recomendação para aplicação.
ANALISIS FINANCIAL DISTRESS DENGAN MENGGUNAKAN METODE ALTMAN Z-SCORE PADA PERUSAHAAN PT. UNITEX, TBK YANG TERDAFTAR DI BURSA EFEK INDONESIA

Tujuan penelitian ini adalah untuk mengetahui gambaran FinancialDistress PT UNITEX, Tbk yang Terdaftar di Bursa Efek Indonesia pada tahun 2006-2014 berdasarkan metode Altman Z-score serta mengetahui faktor dominan yang menyebabkan Financial Distress PT. UNITEX, Tbk yang Terdaftar di Bursa Efek Indonesia pada tahun 2006-2014 dengan menggunakan Metode Altman Z-score. Metode yang digunakan dalam penelitian ini adalah metode analisis deskriptif dan induktif. Pengujian dilakukan dengan menggunakan bantuan program MS Excel dengan rasio Altman Z Score. Hasil penelitian dapat disimpulkan sebagai berikut : 1) Rata-rata Z Score selama tahun 2006 hingga tahun 2014 berada pada angka minus 2,79 atau berada di bawah angka 1,88. Ini berarti PT. Unitex, Tbk benar-benar dalam posisi sedang mengalami financial distress atau masalah keuangan yang serius. 2) Faktor-faktor Retained Earnings to Total Assets Ratio, Net Working Capital to Total Asset Ratio, dan Earnings Before Interest and Taxes to Total Asset Ratio adalah secara berurutan merupakan faktor-faktor yang paling dominan menyebabkan terjadinya financial distress pada PT. Unitex, Tbk. Hasil ini menerimahipotesis penelitian ini yang menyatakan bahwa “Diduga Retained Earnings to Total Assets Ratio, Net Working Capital to Total Asset Ratio, dan Earnings Before Interest and Taxes to Total Asset Ratio merupakan faktor yang dominan menyebabkan terjadinya Financial Distress PT UNITEX, Tbk yang Terdaftar di Bursa Efek Indonesia”.