Miracle-dz/UniFAR-FTUs huggingface dataset:
Diabetes and Oral Health (DiabOH): The Perspectives of Primary Healthcare Providers in the Management of Diabetes and Periodontitis in China and Comparison with Those in Australia

Diabetes and periodontal disease are highly prevalent conditions around the world with a bilateral causative relationship. Research suggests that interprofessional collaboration can improve care delivery and treatment outcomes. However, there continues to be little interprofessional management of these diseases. DiabOH research aims to develop an interprofessional diabetes and oral health care model for primary health care that would be globally applicable. Community medical practitioners (CMPs), community health nurses (CNs), and dentists in Shanghai were recruited to participate in online quantitative surveys. Response data of 76 CMPs, CNs, and dentists was analysed for descriptive statistics and compared with Australian data. Health professionals in China reported that, while screening for diabetes and periodontitis, increasing patient referral and improving interprofessional collaboration would be feasible, these were not within their scope of practice. Oral health screening was rarely conducted by CMPs or CNs, while dentists were not comfortable discussing diabetes with patients. Most participants believed that better collaboration would benefit patients. Chinese professionals concurred that interprofessional collaboration is vital for the improved management of diabetes and periodontitis. These views were similar in Melbourne, except that Shanghai health professionals held increased confidence in managing patients with diabetes and were more welcoming to increased oral health training.
A quarter century of usable security and privacy research: transparency, tailorability, and the road ahead

ABSTRACT In the last decades, research has shown that both technical solutions and user perceptions are important to improve security and privacy in the digital realm. The field of ‘usable security’ already started to emerge in the mid-90s, primarily focussed on password and email security. Later on, the research field of ”usable security and privacy” evolved and broadened the aim to design concepts and tools to assist users in enhancing their behaviour with regard to both privacy and security. Nevertheless, many user interventions are not as effective as desired. Because of highly diverse usage contexts, leading to different privacy and security requirements and not always to one-size-fits-all approaches, tailorability is necessary to address this issue. Furthermore, transparency is a crucial requirement, as providing comprehensible information may counter reactance towards security interventions. This article first provides a brief history of the research field in its first quarter-century and then highlights research on the transparency and tailorability of user interventions. Based on this, this article then presents six contributions with regard to (1) privacy concerns in times of COVID-19, (2) authentication on mobile devices, (3) GDPR-compliant data management, (4) privacy notices on websites, (5) data disclosure scenarios in agriculture, as well as (6) rights under data protection law and the concrete process should data subjects want to claim those rights. This article concludes with several research directions on user-centred transparency and tailorability.
Drivetrain Oscillation Analysis of Grid Forming Type-IV Wind Turbine

The grid forming strategy can be applied in the wind turbine system and offer better grid supporting service than the traditional grid following strategy. A popular method is to implementing the grid forming strategy in the grid side converter (GSC) system while the machine side converter (MSC) system controls the DC-link voltage. Compared to the grid following wind turbine (GFL-WT), the role of GSC and MSC are exchanged in the grid forming wind turbine (GFM-WT), therefore the electrical torque response of GFM-WT is different from the one of GFL-WT and the drivetrain oscillation caused by the incompatibility between electrical torque response and drivetrain model needs to be analyzed. This paper investigates the drivetrain oscillation of the virtual synchronous generator (VSG) based type-IV wind turbine. The mechanism of drivetrain oscillation is explained by the linearized model in frequency domain. Then, a damping control strategy is proposed to suppress the drivetrain oscillation, and its effectiveness is verified by time domain simulation.
A BiCMOS SiGe low phase noise tunable 30 GHz RF source using a frequency tripler and a VCO

In this paper, we present a 10/30GHz tripler and an X band VCO, integrated on a single chip, using a 0.35/spl mu/m, 60GHz-F/sub MAX/ BiCMOS SiGe technology. These two circuits are used together in order to implement a low phase noise MMIC 30GHz source. The tripler exhibits a conversion gain in the -5dB range. The VCO exhibits a phase noise of -87dBc/Hz at a 100kHz frequency offset. The supply voltage of the chip is 7 volts and the total DC power consumption is in the range of 900mW. The circuit exhibits a surface area less than 1mm/sup 2/ (probe pads area excluded).
Speaking but not gesturing predicts event memory: a cross-linguistic comparison

Abstract Every day people see, describe, and remember motion events. However, the relation between multimodal encoding of motion events in speech and gesture, and memory is not yet fully understood. Moreover, whether language typology modulates this relation remains to be tested. This study investigates whether the type of motion event information (path or manner) mentioned in speech and gesture predicts which information is remembered and whether this varies across speakers of typologically different languages. Dutch- and Turkish-speakers watched and described motion events and completed a surprise recognition memory task. For both Dutch- and Turkish-speakers, manner memory was at chance level. Participants who mentioned path in speech during encoding were more accurate at detecting changes to the path in the memory task. The relation between mentioning path in speech and path memory did not vary cross-linguistically. Finally, the co-speech gesture did not predict memory above mentioning path in speech. These findings suggest that how speakers describe a motion event in speech is more important than the typology of the speakers’ native language in predicting motion event memory. The motion event videos are available for download for future research at https://osf.io/p8cas/.
Evaluation of effect of intravenous dexmedetomidine infusion on intra-operative hemodynamic and recovery profile in patients undergoing intracranial surgery under general anaesthesia

Background: The brain is critically dependent on uninterrupted blood flow for the supply of nutrients and clearance of metabolites. Both an increase and decrease in the blood flow are harmful to the brain. Aim: This study aimed to evaluate the effectiveness of Dexmedetomidine (in comparison to normal saline) in maintaining haemodynamic parameters during laryngoscopy among patients undergoing elective intracranial surgery. Material and methods: This was a single centre, parallel-group, 1:1, and single-blind, placebocontrolled, randomised control study. 60 patients undergoing elective neurosurgery were randomised to intravenous dexmedetomidine (0.4mcg/kg/hr) or a similar volume of normal saline. Following outcomes were measured: heart rate, mean arterial pressure (MAP), the dose of thiopentone, time to extubation, and level of sedation. Results: The time for extubation in the Group D group was 5.23 minutes and in the Group C group, it was 8.6 minutes (p<0.0001). At endline, the sedation score among participants in group D was less in comparison to participants in group C. The mean dose of thiopentone required in group D participants was significantly less than those required by participants in group C (p<0.0001). Dexmedetomidine effectively blunted the increase in heart rate and mean arterial pressure both at intubation and extubation. There was a difference of 21% point between the MAP values between group D and group C participants at intubation. Conclusion: Dexmedetomidine has an anaesthetic sparing effect, and it reduced the time of recovery among patients undergoing neurosurgery.
Numerical study of lubricant oil drop induced pre-ignition in engines

Pre-ignition in engines has been the subject of current research with the advent of boosted engines for reduced fuel consumption and emissions. Lube-oil-drop-induced pre-ignition was observed in large natural gas engines which find application in the marine industry. In order to understand the mechanism of pre-ignition in the present study, a computational simulation of pre-ignition by lube-oil drops was performed for a production natural gas marine engine. The engine grid was generated using ICEM tool. For CFD simulations, an in-house version of KIVA4 code was employed. Oil throw-off into the combustion chamber was modeled by a lube oil stripping model, which sets the criteria for oil drops to be stripped from the piston rings/crevice regions and enter the combustion chamber. To capture the ignition caused by the stripped oil drops precisely, single particle ignition cell (SPIC) model was used that utilizes computations of thermal and chemical changes in refined grid cells for the lube oil containing computational cells. For modeling chemical kinetics, a reduced lube oil reaction mechanism previously developed was used. Factors affecting the lube oil stripping process such as thickness, velocity, and temperature of the lube film and its subsequent pre-ignition behavior were studied and discussed. Higher initial thickness, higher film temperature and higher initial film velocity all lead to earlier stripping of lube-oil film into the combustion chamber. Once the film is stripped, keeping the local lube vapor equivalence ratio low is the key to prevent pre-ignition.
SOX4-mediated FBW7 transcriptional upregulation confers Tamoxifen resistance in ER+ breast cancers via GATA3 downregulation.

AIM Tamoxifen-mediated endocrine therapy has been standard treatment for ER+ breast cancers; however, majority of them acquire resistance leading to disease relapse. Although numerous substrates of E3 ligase FBW7 are known, only a handful of factors that regulate FBW7 expression and function are reported. In particular, there remains a lack of in-depth understanding of FBW7 transcriptional regulation. MATERIALS AND METHODS Luciferase reporter assay was performed after cloning full length and truncated FBW7 promoters followed by Chromatin immunoprecipitation assay to validate binding of SOX4 on FBW7 promoter. Transcriptional regulation of FBW7 by SOX4 and their biological consequences with respect to ER+ breast cancer was then evaluated using immunoblotting and other cell based assays. KEY FINDINGS SOX4 positively regulates FBW7 at transcriptional level by binding to three putative SOX4 biding sites within 3.1 kb long FBW7 promoter. Analysis of publicly available RNAseq datasets also showed a positive correlation between SOX4 and FBW7 mRNA in cancer cell lines and patient samples. qPCR and Immunoblotting confirmed that transiently or stably expressed SOX4 induced both endogenous FBW7 mRNA and protein levels. Our findings further demonstrated that increased levels of SOX4 and FBW7 in MCF7 mammospheres promoted cancer stemness and tumor cell dormancy. We further showed that both MCF7 mammospheres and MCFTAMR cells had elevated SOX4 levels which apparently enhanced FBW7 to potentiate GATA3 degradation leading to enhanced stemness, tumor dormancy and Tamoxifen resistance in MCF7TAMR as well as patients with ER+ breast cancers. SIGNIFICANCE Targeting SOX4-FBW7-GATA3 axis may overcome tamoxifen resistance in ER+ breast cancers.
An exploration of the consistency limits of the analytical hierarchy process and its impact on contractor selection

ABSTRACT As project failure risk is reduced with the inclusion of additional factors when choosing a contractor, so too is client risk. As an approach to multi-criteria decision-making, the analytical hierarchy process (AHP) is explored to determine whether the traditional AHP (consistency ratio 0.1) and the weakly consistent AHP (consistency ratio 0.5–0.1), currently used for contractor selection, produce the same result. A case study comparing both methods reveals that the top-ranked contractor was the same while the ranking of the remaining contractors were different. Because choosing the right contractor can mean the difference between project success and failure, the consistency rule for the traditional AHP should be used for contractor selection, and not the weakly consistent AHP, especially as inconsistency increases random outcomes. This finding becomes important if the first-choice contractor opts out of a contract or is terminated by the client and a suitable second choice must be made from the original bids.
WISP, Wearable Inertial Sensor for Online Wheelchair Propulsion Detection

Manual wheelchair dance is an artistic recreational and sport activity for people with disabilities that is becoming more and more popular. It has been reported that a significant part of the dance is dedicated to propulsion. Furthermore, wheelchair dance professionals such as Gladys Foggea highlight the need for monitoring the quantity and timing of propulsions for assessment and learning. This study addresses these needs by proposing a wearable system based on inertial sensors capable of detecting and characterizing propulsion gestures. We called the system WISP. Within our initial configuration, three inertial sensors were placed on the hands and the back. Two machine learning classifiers were used for online bilateral recognition of basic propulsion gestures (forward, backward, and dance). Then, a conditional block was implemented to rebuild eight specific propulsion gestures. Online paradigm is intended for real-time assessment applications using sliding window method. Thus, we evaluate the accuracy of the classifiers in two configurations: “three-sensor” and “two-sensor”. Results showed that when using “two-sensor” configuration, it was possible to recognize the propulsion gestures with an accuracy of 90.28%. Finally, the system allows to quantify the propulsions and measure their timing in a manual wheelchair dance choreography, showing its possible applications in the teaching of dance.
Etiology-Related Outcome of Endovascular Therapy in Posterior Circulation Stroke Compared to Anterior Circulation Stroke

Background and Purpose We investigated the impact of stroke etiology on the endovascular treatment (EVT) procedure and clinical outcome of posterior circulation stroke (PCS) patients with EVT compared to anterior circulation stroke (ACS) patients. Methods We retrospectively analyzed ischemic stroke patients who underwent EVT between January 2012 and December 2020. Enrolled ACS and PCS patients were compared according to etiologies (intracranial arterial steno-occlusion [ICAS-O], artery-to-artery embolic occlusion [AT-O], and cardioembolic occlusion [CA-O]). EVT procedure and favorable clinical outcomes at 3 months (modified Rankin Scale 0–2) were compared between the ACS and PCS groups for each etiology. Results We included 419 patients (ACS, 346; PCS, 73) including 88 ICAS-O (ACS, 67; PCS, 21), 66 AT-O (ACS, 50; PCS, 16), and 265 CA-O (ACS, 229; PCS, 36) patients in the study. The onset-to-recanalization time was longer in the PCS group than in the ACS group (median 628.0 minutes vs. 421.0 minutes, P=0.01). In CA-O patients, the door-to-puncture time was longer, whereas the puncture-to-recanalization time was shorter in the PCS group than in the ACS group. The proportions of successful recanalization and favorable clinical outcomes were similar between the ACS and PCS groups for all three etiologies. Low baseline National Institutes of Health Stroke Scale (NIHSS) scores and absence of intracerebral hemorrhage at follow-up imaging were associated with favorable clinical outcomes in both groups, whereas successful recanalization (odds ratio, 11.74; 95% confidence interval, 2.60 to 52.94; P=0.001) was only associated in the ACS group. Conclusions The proportions of successful recanalization and favorable clinical outcomes were similar among all three etiologies between PCS and ACS patients who underwent EVT. Initial baseline NIHSS score and absence of hemorrhagic transformation were related to favorable outcomes in the PCS and ACS groups, whereas successful recanalization was related to favorable outcomes only in the ACS group.
Mixed-frequency models for tracking short-term economic developments in Switzerland

We compare several methods for monitoring short-term economic developments in Switzerland. Based on a large mixed-frequency data set, the following approaches are presented and discussed: factor-based information combination approaches (including factor model versions based on the Kalman filter/smoother, a principal component based version and the three-pass regression filter), a model combination approach resting on MIDAS regression models and a model selection approach using a specific-to-general algorithm. In an out-of-sample GDP forecasting exercise, we show that the considered approaches clearly beat relevant benchmarks such as univariate time-series models and models that work with one or a small number of indicators. This suggests that a large data set is an important ingredient for successful real-time monitoring of the Swiss economy. The models using a large data set particularly outperform others during and after the Great Recession. Forecast pooling of the most-promising methods turns out to be the best option for obtaining a reliable nowcast for the Swiss economy.
Analysis of Ethernet Load on Various Nodes of Star Network Using Opnet

In this paper our main emphasis is to understand how Ethernet load varies with increase of nodes in star network. Here we have explained different topologies for a particular network and special emphasis is on star topology and also designed their modified forms such as double star and tri star network using Opnet (optical network simulator) and studied Ethernet load on the network.
Analysis of Sentiment and Personalised Recommendation in Musical Performance

Music performance research is a comprehensive study of aspects such as emotional analysis and personalisation in music performance, which help to add richness and creativity to the art of music performance. The labels in this paper in collaborative annotation contain rich personalised descriptive information as well as item content information and can therefore be used to help provide better recommendations. The algorithm is based on bipartite graph node structure similarity and restarted random wandering. It analyses the connection between users, items, and tags in the music social network, firstly constructs the adjacency relationship between music and tags, obtains the music recommendation list and indirectly associated music collection, then fuses the results according to the proposed algorithm, and reorders them to obtain the final recommendation list, thus realising the personalised music recommendation algorithm. The experiments show that the proposed method can meet the personalised demand of users for music on this dataset.
Influence of Maximum Particle Size, Fines Content, and Dust Ratio on the Behavior of Base and Subbase Coarse Aggregates

Unbound aggregate base and subbase layers are the main load-bearing layers in a pavement structure. Size and shape properties of these aggregate materials should be controlled to ensure proper workability during construction and improved performance for pavement longevity. The effects of gradation, maximum particle size, fines content (percentage passing the No. 200 sieve), and dust ratio on the quality of aggregates were investigated by performing many soaked California bearing ratio tests on a crushed limestone material. The dust ratio represents the amount of fines content divided by the amount of minus No. 40 sieve material. The dust ratios studied were 0.4, 0.6, and 1.0. Two gradations commonly used in Illinois, with maximum particle sizes of 1 in. and 2 in. , were studied to analyze the effect of fines content with respect to maximum particle size in the gradation. A typical range of fines contents (i.e., 5%, 8%, and 12%) was also considered. The results show that the gradation, dust ratio, and fines content should be taken into account in the selection of aggregate properties for stability requirements. Aggregates with larger maximum size particles provide high strength, and they are not affected as much as aggregates with smaller maximum size particles by an increase in fines content. The aggregates with smaller maximum size particles provide lower strength. It was also concluded that samples with a dust ratio of 1.0 do not necessarily result in an aggregate material with low strength.
New concept of in/out air quality control in livestock buildings

The object of this research is the new concept of the original universal system for air quality and energy control in laboratory conditions (wet scrubbing system) based on the ? clean air in/out? principle. Namely, the process involves a partial or complete exchange of recirculated treated air. From the aspect of water, as a pure medium, the system is characterized by broad application in the open, semi-open, and closed air treatment systems: primarily in the breeding and accompanying agricultural facilities, industrial, cultural, sports, tourist, medical and other controlled spaces. The analysis showed that the system at its inlet unit and with the block structure and logical phase development, proved energy, environmental and qualitative efficiency in the removal of PM10 and PM2.5 particles from the controlled dust doses in laboratory air. The measurements of PM10 and PM2.5 concentrations were performed with two Alphasense OPC-N3 optical counters at the inlet and outlet of the system. Five operating regimes with frequency regulated number of revolutions of the turbo elements that was taken as an independent variable, achieved different degrees of removal of PM10 and PM2.5 from the treated laboratory air: 97.70 to 98.53% and 62.19 to 75.75%, respectively. The assessment of system energy use was done by parallel measuring of electric power and comparative deviations of its absolute values in the first decimal. Energy consumption for the treatment of 1m3 of air ranged from 0.00011 to 0.00016 kWm-3. Statistical analysis of qualitative indicators revealed significant differences between the operating regimes and the obtained values.
Is it the time of a paradigm shift from intra-articular corticosteroid injections to regenerative medicine in osteoarthritis? review article

This article addresses the best practice in managing osteoarthritis (OA), weighing the benefits and risks of various intra-articular therapies. For many decades we had used intra-articular injections of corticosteroids (IACSs) as the only option after analgesics and physical therapy to help symptoms in patients who suffer from mild to moderate OA until they get ready for joint replacement. In advanced degenerative diseases, particularly in the elderly, we go directly to surgery except when there are multiple comorbidities, then surgery is not an option; thus, IACS injection is the only option left. Furthermore, in individuals suffering from renal disease, peptic ulcer, diabetes, or heart failure, we cannot use regular non-steroidal anti-inflammatory medicines, going the only option for frequent IACSs. Several kinds of literature suggest some harmful effects of IACSs. These include accelerated OA of the cartilage, subchondral insufficiency fracture, joint infection, and osteonecrosis. As the science progresses, regenerative therapies (RTs) emerge, including hyaluronic acid (HA), platelet-rich plasma (PRP), and mesenchymal stem cell (MSC) therapy. RTs carry an excellent safety profile compared to IACSs. That shift in paradigm by moving away from using IACSs in OA to those RTs has shown more prolonged symptomatic effects, slowing or stopping the progression of OA and sometimes regeneration of the cartilage and surrounding tissues.