Miracle-dz/UniFAR-FTUs huggingface dataset:
Energy Saving Assessment for Building Envelope of Supermarket Based on EnergyPlus and Openstudio

In this paper, a supermarket model located in Kathmandu is established by simulation software EnergyPlus. As one possible approach to improving the energy performance of the commercial building, this study develops an whole building energy simulation model to investigate the influence of two types of alternative walls – a insulated wall, a brick wall with 50 mm air gap and 4 inch additional brick wall on the energy performance of Bhatbhateni department store building at Krishna Galli, Lalitpur, Nepal. Single and double glazed glasses with varies thermal properties has been analyzed. This study finds that the 1 inch insulated external walls significantly improve the performance compared to the non-insulated wall. It is also found that the double glazed glass window models Envision and Reflectasol reduces the largest amount of energy. The results of this study can be used as basis data for estimating the potential energy saving with the replacement of alternative envelope (wall and window) under similar climate and orientation of the buildings.
Participatory Game Design and Children

This Ph.D. thesis revolves around participatory design with children for the early design of games for them. The Ph.D. research aimed at developing a method and guidelines for participatory game design with children. The Ph.D. work adopted an empirical research approach for developing the method and guidelines. The method draws from prior work, from different research areas, to propose new ideas or relationships between existing constructs. Specifically, different research areas from design and education were crossfertilized in the method in order to sustain engagement, learning and collaboration during a participatory game design experience, prolonged and fragmented in time. Principles of gamification of learning and gamified probes were used for sustaining engagement throughout the experience, and cooperative learning was introduced for fostering democratic collaboration. The method emerged iteratively through field studies, gathering both qualitative and quantitative data, and it matured through an iterative learning process. This Ph.D. thesis presents firstly the relevant work on which the method breeds, secondly the method itself, and subsequently the major field studies. Finally, the thesis presents guidelines for conducting a participatory game design experience with children, and resulting from findings of field studies.
AC losses in superconductors : a multi-scale approach for the design of high current cables

The work reported in this PhD deals with AC losses in superconducting material for large scale applications such as cables or magnets. Numerical models involving FEM and integral methods have been developed to solve the time transient electromagnetic distributions of field and current density with the peculiarity of the superconducting constitutive E-J equation. Two main conductors have been investigated for two ranges of superconducting cables. First, REBCO superconductors working at 77 K are studied and a new architecture of conductor (round wires) for 3~kA cables. Secondly, for very high current cables, 3-D simulations on MgB2 wires are approach and solved using FEM modeling. The following chapter introduced new development used for the calculation of AC losses in DC cables. The thesis ends with the use of the developed numerical model on a practical example in the BEST-PATHS project: a 10 kA MgB2 demonstrator.
Robo-Erectus Jr-2013 KidSize Team Description Paper.

This paper provides a brief description of Robo-Erectus Jr (REJr) that is set to participate in the KidSize category in the Humanoid League of Robocup 2013. Robo-Erectus Jr-Bv are a series of KidSize humanoid developed in the Advanced Robotics and Intelligent Control Centre of Singapore Polytechnic. The latest version of the Robo-Erectus Jr-Bv humanoids are the MkII+ and MkIII.
Gamification, serious games, simulations, and immersive learning environments in knowledge management initiatives

Purpose The purpose of this paper is to provide an in-depth and critical review of the literature and theories on knowledge, knowledge management (KM) as well as the concepts and approaches relating to organizational learning and the knowledge-based economy. The paper also provides more details and definitions of various issues around gamification. Design/methodology/approach Several sources have been reviewed and consulted including various mainstream referred journals focusing on KM and gamification as well as books, online databases, governmental reports, and statistics, etc. Findings Game-based learning (GBL) in business must align with the learning goals and outcomes of training and development, and clearly demonstrate that learning can be evaluated and achieved. Serious game experiences drive personal change and transformation by generating an attitude of acceptance of the challenge, motivation to achieve, and constant innovation through participant commitments. Simulations push the participant into experiencing an immersive environment. Finally, gamification, as a collection of techniques, may be applied to the educational and workplace activities, or used as a wrapper for GBL, serious games, and simulations. Research limitations/implications We are on a unique and unusual path to revitalizing and reinvigorating the educational experience. This new path is not about throwing a LMS at faculty and hoping it sticks. This new path is about creating faculty who are mentors, coaches, and life-long learners who understand the research implications of applying game-based learning in the classroom, as well as the workforce. Practical implications Higher educational teaching as well as corporate LTD (Learning, Training, and Development) are being significantly disrupted. The innovation taking place in teaching requires more experiential learning, the kind of learning stimulated with serious games, simulations, immersive learning environments, and gamification. This issue will help to outline disruptive approaches that work. Originality/value This paper provides a review of the emerging trends and cases where gamification, simulations, serious games, immersive learning environments, virtual reality, and augmented reality are applied to the deployment of knowledge-based initiatives.
Evaluation of relationship between digit ratio (2D: 4D) and epilepsy: Can 2D:4D be a clue for epileptogenesis?

Objective: The aim of the study was to investigate the possible association between the 2D:4D ratio and epilepsy in male and female adults, and to compare the ratios of epilepsy patients and healthy control subjects. Patients and Methods: A case-control study carried out at a neurology and biophyiscs department in Ankara Yıldırım Beyazıt University, Faculty of Medicine from May 2016 to January 2017. The 2D:4D ratios of both the left and right hands of 172 epilepsy patients and 202 matched healthy controls were recorded. All participants also completed the Edinburgh handedness inventory. Results: A significant positive correlation between the 2D:4D ratio and epilepsy was found for both females and males; a lower ratio for the left hand was associated with a higher possibility of epilepsy. In addition, a lower ratio in a specific hand was associated with that hand being used to complete the handedness test. Conclusions: The 2D:4D ratio serves as a predictor for increased risk of epilepsy. Thus, it could be used as a marker to differentiate patients with from controls.
Prognostic significance of tumor-infiltrating lymphocytes (TILs) and their characterization in canine melanocytic tumors.

The study of the immune response in several types of tumors has been rapidly increasing in recent years with the dual aim of understanding the relationship between neoplastic and immune cells as well as identifying targets for cancer immunotherapy. Despite being considered one of the most immunogenic tumor types, melanoma can progress in the presence of abundant lymphocytic infiltration, therefore suggesting that the immune response is not able to efficiently control tumor growth. The purpose of this study was to investigate whether the density, distribution and grade of tumor-infiltrating lymphocytes (TILs) in 97 canine melanocytic tumors is associated with histologic indicators of malignancy and can be considered a prognostic factor in the dog. As a further step in the characterization of the immune response in melanocytic tumors, an immunohistochemical investigation was performed to evaluate the two main populations of TILs, T-lymphocytes (CD3 + ) and B-lymphocytes (CD20 + ). The results of our study show that TILs are present in a large proportion of canine melanocytic tumors, especially in oral melanomas, and that, differently from humans, the infiltrate is usually mild. The quantity of CD20 + TILs was significantly associated with some histologic prognostic factors, such as the mitotic count, the cellular pleomorphism and the percentage of pigmented cells. Remarkably, a high infiltration of CD20 + TILs was associated with tumor-related death, presence of metastasis/recurrence, shorter overall and disease-free survival, increased hazard of death and of developing recurrence/metastasis, hence representing a potential new negative prognostic factor in canine melanocytic tumors. a commercially available rabbit antibody against CD20 and a rabbit polyclonal antibody against CD3 (1:200; 0452; were used. Antigen retrieval was achieved in a preheated Tris-EDTA buffer solution (pH 9.0) for the CD3 antibody, while no antigen retrieval was performed for the CD20 antibody. Endogenous peroxidases were blocked using 3% H 2 O 2 for 5 minutes at room temperature and protein block performed with a commercially available kit (ab93677; Abcam, Cambridge, UK). Slides were incubated with primary antibodies for 1 hour in a humidiﬁed chamber at room temperature. Afterwards they were incubated with an ABC ready-to-use kit (ab93677; Abcam, Cambridge, UK) following the manufacturer’s instructions. Positive reaction was revealed with 3-amino-9-ethilcarbazole (Dako, Glostrup, Denmark). Carazzi’s hematoxylin was used as a counterstain. Coverslips were mounted with Faramount Mounting Medium (Dako, Glostrup, Denmark). Normal canine lymph node was used as positive control. Negative controls were performed omitting the primary antibody and incubating tissue sections with Tris–phosphate-buffered saline buffer. Only TILs defined according to Clark et al. and Clemente et al. this study (CD3 + or CD20 + TILs).
Kil Zeminlerde Magnezyum Klorürün (MgCl 2 ) Etkisi

Behavior of clayey soil shows changes according to the unit volume weight, gap ratio, microstructure, grain diameter distribution, clay mineralogy, plasticity and the properties of the liquid in the gap. Water in the gap is polluted in sometimes. Specifically, salting occurs on the ground due to mineral decomposition, withdrawal of the ocean, irrigation processes, leaks in solid waste depots and operations. Various studies were carried out for this reason and reported in the literature. In this study, firstly, the results of previous studies about the behavior changes that occur as a result of the interaction of magnesium chloride and other salts with clay soil are presented.
The efficacy of Bifidobacterium quadruple viable tablet in the treatment of diarrhea predominant irritable bowel syndrome: a randomized, double-blind, placebo-controlled, multicenter trial. CURRENT STATUS: POSTED

Background Irritable bowel syndrome (IBS) is one of the most acommon functional gastrointestinal disorders characterized by recurrent abdominal pain associated with defecation or a change in bowel habits. Leading to significant negative effect on patients’ quality of life and huge financial burden to health system, the management of IBS is a great challenge. Probiotics are considered as an effective therapy, however, in a lack of high-quality evidence of efficacy, no specific strain- and dose-probiotics were recommended in clinical guidelines. This study aims to evaluate the efficacy of the bifidobacterium quadruple viable tablet in the treatment of IBS-D. Methods/design A multicenter randomized controlled trial will be performed in fourteen hospitals. A total of three hundred patients fulfill the eligible criteria will be stratified divided into an experimental group and a control group randomly in a ratio of 1:1. The experimental group is treated with the bifidobacterium quadruple viable tablet while the control group is treated with placebo. All the patients will receive a 4-week treatment and a 2-week follow-up. The primary outcome is the effectiveness in improving abdominal pain and stool consistency, the secondary outcome include evaluation of overall symptom relief, frequency of defecation, bloating, urgency of defecation, remedial medication, score of IBS-QOL and changes of microbiota and metabonomics. Physical examination, vital signs, laboratory tests, adverse events and concomitant medication will be taken into account for intervention safety assessment during the trial. Discussion This multicenter randomized controlled trial may provide high-quality evidence on the efficacy of the bifidobacterium quadruple viable tablet for IBS-D on both physical and mental dimensions in China. To fill the gap of previous probiotics intervention studies, in addition, this study will also present safety assessment which will be a significant emphasis. The recruitment of participants will be mainly via physician referrals from the gastroenterology clinics. Internet publicity and posters for advertisements will also be adopted. Those who are willing to participant in this trial will need to contact the investigator and research assistants by telephone.
Evaluating the Importance of Factors Effecting the Consumer Behavior in new Dialysis Machine in Iran-Tehran

Background and Aim: The health care industry is very critical base on its relation to human life. The amount of research and changes in the diagnostic techniques and procedures, therapeutic techniques, drugs and equipment are very vast and fast. In order to prevent the waste of resources, it is required to understand the needs and wants of the market. Therefore, it is very crucial to understand the patient’s opinion. Methods: By reviewing the literature of consumer behavior theories, a number of factors are classified into seven categories. Based on this classification a questionnaire was developed. The main respondents were parents of a child who is suffering from renal failure. Then, two statistical tests were held using t-test in order to identify the importance and prioritizing of each factor also correlation coefficient to understand the availability and strength of relationship among factors. Results: The results base on the statical tests indicates that the three groups of factors do not affect consumer behavior. The rest of the factors have an influence on consumer behavior regarding a new product. Base on the result hospitals and clinics that have hemodialysis sections with the specialty of delivering service to children should recognize the product accuracy, the lowest possible price, with vast of informative activity to parents and the children and doctors. Conclusion: These approaches will smooth the way for hospitals and clinics to launch new services to renal failure patients.
Cleavage-dependent Ligation by the FLP Recombinase CHARACTERIZATION OF A MUTANT FLP PROTEIN WITH AN ALTERATION IN A CATALYTIC AMINO ACID*

The FLP recombinase of the 2 (cid:109) M plasmid of Saccharomyces cerevisiae belongs to the integrase family of recombinases whose members have in common four absolutely conserved residues (Arg-191, His-305, Arg-308, and Tyr-343). We have studied the mutant protein FLP R308K in which the arginine residue at position 308 has been replaced by lysine. Although FLP R308K was previously reported to be defective in ligation of certain substrates (Pan, G., Luetke, K., and Sadowski, P. D., Mol. Cell. Biol. 13, 3167–3175, 1993b), we show in this work that the protein is able to ligate those substrates that it can cleave (cleavage-dependent ligation activity). FLP R308K is defective in in vitro recombination and in strand exchange. It is able to carry out strand exchange at one of the two cleavage sites of the FLP recognition target site (FRT site), but is defective in strand exchange at the other cleavage site. These results are consistent with a model in which wild-type FLP initiates recombi- nation only at one of the two cleavage sites. FLP R308K may be defective in the initiation of recombination.
Improving provider productivity: Impact 1 Running Head: Improving Provider Productivity: Impact of Coder Improving Provider Productivity: Impact of Coder-Coaches on Provider Documentation and Coding

The military health system (MHS) is beginning a dramatic shift towards controlling costs and increasing productivity. In order to achieve these goals, the MHS initiated the Jumpstart Program, which provided Tripler Army Medical Center (TAMC) $924,000 to hire 12 coder-coaches and 3 consultants to increase provider workload by 69,900 relative value units (RVUs). The coder-coaches directly assist and coach providers in improving the documentation and coding of encounters. The purpose of this study is to investigate the impact of coder-coaches on provider productivity, measured in RVUs, through improved documentation and coding at three clinics at TAMC during the first quarter (Q1) FY06. The results of the study support the function of coder-coaches in increasing RVUs through better coding and documentation. The full-model regression equation accounted for (R 2) 66.73% of the variance in productivity (F 4, 40 = 20.06, p<.000). Analysis of variance (ANOVA) test showed that the Family Practice (F 2 8 = 18.06, p<.01), Orthopedic (F 2, 8 = 17.23, p<.01), and Obstetrics clinics (F 2.8 = 8.81, p<.01) had higher productivity during Q1 FY06 compared to the same quarter in FY05. Specialty care setting (Orthopedic and Obstetrics) had higher productivity than the primary care (Family Practice) setting (F 2, 8 = 24.92, p<.000). The study also supports the need to have experienced coder-coaches. Coder-coaches with at least six months of coding experience generated higher RVUs (.38 RVUs per encounter in Orthopedic clinic, p<.01) than coders in the Obstetrics clinic who had no coding experience (F 2 8 = 49.49, p<.000). Recommendations to the commander include supporting the codercoach initiative in FY07, hiring only experienced coders, and placing the majority of the coder-coaches in the specialty care setting. Improving provider productivity: Impact 4 Table of
Low-Cost Inkjet-Printed Wireless Sensor Nodes for Environmental and Health Monitoring Applications

Low-Cost Inkjet-Printed Wireless Sensor Nodes for Environmental and Health Monitoring Applications Muhammad Fahad Farooqui Increase in population and limited resources have created a growing demand for a futuristic living environment where technology enables the efficient utilization and management of resources in order to increase quality of life. One characteristic of such a society, which is often referred to as a ‘Smart City’, is that the people are well informed about their physiological being as well as the environment around them, which makes them better equipped to handle crisis situations. There is a need, therefore, to develop wireless sensors which can provide early warnings and feedback during calamities such as floods, fires, and industrial leaks, and provide remote health care facilities. For these situations, low-cost sensor nodes with small form factors are required. For this purpose, the use of a low-cost, mass manufacturing technique such as inkjet printing can be beneficial due to its digitally controlled additive nature of depositing material on a variety of substrates. Inkjet printing can permit economical use of material on cheap flexible substrates that allows for the development of miniaturized freeform electronics. This thesis describes how low-cost, inkjet-printed, wireless sensors have been developed for real-time monitoring applications. A 3D buoyant mobile wireless sensor
Evaluation of School-Based Creating Awareness of Cystic Echinococcosis: A Pilot Study

: Human cystic echinococcosis (CE) is the most prevalent disease in Europe, and probably accounts for more than 95% of the estimated 2-3 million global cases. CE is a fatal and serious disease. Turkey is among the countries where this problem still poses a public threat. This study was a pilot study to create the awareness of CE among 10 different districts of Izmir province, Turkey. Awareness raising seminars are essential component of this study for students and schoolteachers. Questionnaire forms were created and applied before and after the presentations. Printed materials, posters and brochures were disseminated and posters put on the walls or boards where students can see continuously. Even 4090 students attended to the trainings, questionnaires were filled by 3793 of the students. Out of 3793 students, 1978 (52.1%) were female and 1815 (47.9%) were male. The majority of students (94.2%) did not know anything about this disease. 93.1% students were stated that there were stray dogs in their environment. More than half of the students were playing with stray dogs. Nearly 90% of the students answered correctly the questions which were asked after presentation.The total number of administrators and teachers who attended to the seminars were 242. This is the first pilot study regarding creating awareness on CE in the Izmir Province, Turkey that covers the big sample-size of children including schoolteachers. This study helped them understand the importance of the problem and how it can be solved by protecting themselves while respecting human and animal rights. It will be used for establishing nationwide control programme.
Cocoa colonic phenolic metabolites are related to blood lipid lowering eﬀects and methylxanthine metabolites and insoluble dietary ﬁbre to anti-inﬂammatory and hypoglycemic eﬀects in humans

Background . In many cocoa intervention studies, health outcomes are related to cocoa components without taking into account the bioavailability of the main bioactive components: phenolic compounds and methylxanthines. Methods . The present work associates the results of bioavailability and randomised controlled crossover studies in humans carried out with similar cocoa products, so that the main phenol and methylxanthine metabolites observed in plasma and urine are associated to the health eﬀects observed in the chronic studies. We outstand that doses of cocoa and consumption rate used are realistic. In the bioavailability study, a conventional (CC) and methylxanthine-polyphenol rich (MPC) cocoa product were used, whereas in the chronic study a dietary ﬁbre-rich (DFC) and polyphenol-rich (PC) product were studied in healthy and cardiovascular risk subjects. Results and Discussion . The main phenolic metabolites formed after CC and MPC intake, 5-(4’-hydroxyphenyl)-γ-valerolactone-3’-sulfate, 3’-methyl-epicatechin-5-sulfate, 4-hydroxy-5-(4’-hydroxyphenyl)valeric acid-sulfate, 5-phenyl-γ-valerolactone--sulfate and 5-(4’-hydroxyphenyl)-γ-valerolactone-3’-glucuronide, Abstract Background . In many cocoa intervention studies, health outcomes are related to cocoa components without taking into account the bioavailability of the main bioactive Methods . The present work associates the results of bioavailability and randomised controlled crossover studies in humans carried out with similar cocoa products, so that the main phenol and methylxanthine metabolites observed in plasma and urine are 26 associated to the health effects observed in the chronic studies. We outstand that doses 27 of cocoa and consumption rate used are realistic. In the bioavailability study, a conventional (CC) and methylxanthine-polyphenol rich (MPC) cocoa product were used, whereas in the chronic study a dietary fibre-rich (DFC) and polyphenol-rich (PC) product were studied in healthy and cardiovascular risk subjects.