Miracle-dz/UniFAR-FTUs huggingface dataset:
Distribution of Oncogenic Human Papillomavirus Genotypes at High Grade Cervical Lesions above CIN 2 Grade with Histological Diagnosis

High risk human papillomavirus (HR-HPV) is major risk factor for uterine cervical cancer. There are approximately 15 types of HR-HPV. Liquid based cytology samples (116 samples) with high grade cervical lesions belonging to cervical intraepithelial neoplasia (CIN) 2, CIN 3, carcinoma in situ (CIS) and squamous cell carcinoma (SCC) were used after histologic confirmation. HR-HPV genotype assay was conducted using DNA chips. The HR-HPV infection rate was 81.9% with SCC samples showing the highest HR-HPV infection rate of 31%. CIN 3, CIS and CIN 2 showed infection rates of 25%, 16.4% and 9.5%, respectively. According to age with HR HPV infection rate, the 30~39 years-old group showed the highest infection rate by 92.3%. According to distribution with HR HPV genotyping, HPV 16 showed the highest infection rate by 42.3% whereas HPV 33 and HPV 58 showed infection rates of 11.7% and 10.8%, respectively. HPV 18 which is the second most common infected HPV genotype in the world showed 3.6%. Of the three most common oncogenic HR-HPV genotypes in CIN 2, we detected HPV 16, 35, 58; CIN 3 was HPV 16, 33, 58; CIS was HPV 16, 58, 33 (35/52); and SCC was HPV 16, 33, and 18 (31/52/58). Among the HPV 18, CIN 2, CIN 3, CIS and SCC showed 0.9%, 0.9%, 0% and 1.8%, respectively. The most often used preventive vaccines for cervical cancers use HPV 16 and HPV 18 as targets. However, results derived from this study suggest that a preventive vaccine against HPV 16 and HPV 18 would not be optimal for populations in this study.
Fast DOA estimation based on MUSIC symmetrical compressed spectrum

To improve the speed of the estimation of direction of arrival(DOA) and decrease its computational complexity,a new spectrum called multiple signal classification(MUSIC) symmetrical compressed spectrum(MSCS) is proposed based on the analysis of the standard MUSIC algorithm.By creating the conjugate noise subspace,which equals to adding mirror sources in the symmetrical location of true DOAs,the dimension of the noise subspace is descended and MSCS is constructed by the singular value decomposing(SVD) on the intersection of noise subspace and its conjugate subspace.Theoretical analysis and simulation results show that MSCS can be used with arbitrary arrays.Moreover,the new method is capable of reducing the computational complexity of DOA estimation to 50% with a comparable precision to the conventional MUSIC algorithm.
Fractal Theory and the Significance in the Capital Market Research

Tht capital market is not a simple linear system,but it is a very complex non-linear system Therefore,it has very important practical significance to explain and forecast the various complex economy phenomenons by using fractal theory This paper introduces the conceptions of the fractal theory and the definitions of the Hausdorff dimension,topological dimension and box dimension In the last,this paper discusses the significance of the fractal theory in capital market research
Chronic oxytocin administration stimulates the endogenous oxytocin system: an RCT in autistic children

Background: Clinical efficacy of chronic intranasal administration of oxytocin is increasingly explored in autism spectrum disorder (ASD), but to date, little is known regarding its biological effects and in particular how chronic administration regimes impact endogenous oxytocinergic function. Methods: To fill this gap, this double-blind, randomized, placebo-controlled study explored chronic oxytocin administration effects on endogenous salivary oxytocin levels and oxytocin receptor gene (OXTR) epigenetics (DNA methylation) in 8-to-12-year-old children with ASD (n = 79, 16 females). Biological sampling was performed at baseline (pre-treatment), immediately (24 hours) after the four-week oxytocin administration period (12 IU, twice daily) and at a follow-up session, four weeks after the last nasal spray administration. Results: Compared to placebo, children receiving the oxytocin nasal spray displayed significantly higher salivary oxytocin levels 24 hours after the last oxytocin nasal spray administration, but no longer at the four-week follow up session. Regarding epigenetics, oxytocin-induced reductions in OXTR methylation were observed, reflecting a facilitation of oxytocin receptor expression in the oxytocin, compared to the placebo group. Notably, heightened oxytocin levels post-treatment were significantly associated with reduced OXTR DNA methylation and improved feelings of secure attachment. Conclusion: Four weeks of chronic oxytocin administration stimulated the endogenous oxytocinergic system in children with ASD, as evidenced by increased salivary oxytocin levels and reduced OXTR DNA methylation (indicating increased receptor expression).
Finite pole assignment for systems with time-varying input delays

The finite spectrum assignment law of linear systems is extended to single-input single-output systems having a time-varying input delay. State prediction via the given system model is applied together with a state estimation procedure to obtain the feedback signal for the controller. Ordinary pole placement design laws are used for determining the feedback, and estimator gains. The stable feedback control and estimator error systems are obtained to guarantee asymptotic tracking of a given reference model having the same time-varying delay as the original system. >
The Development of Ship Recycling Facility Cluster in Indonesia

With a number of 80.849 units ship operating in Indonesia, the Ministry of Transportation estimates that 29,944 units ship of those vessels have been in service for more than 20 years. Furthermore, recycling ships are necessary. Ship Recycling Facility (SRF) should be ecologically friendly following International Maritime Organization (IMO) policy under the Hong Kong International Convention. Docks, cranes, steel cutters, and warehousing are necessary. SRF facilities, along with ecologically suitable hazardous material treatment. If this facility became a cluster, it would operate more effectively. This study aims to provide a different area in Indonesia where a prospective SRF cluster could grow. This research uses Diamond Porter’s method to determine a country’s comparative economic advantage towards the SRF cluster in Alang City, Gujarat, India, which is the global leader in ship recycling. The factor conditions; related and supporting industries; demand conditions; and firm strategy, structure, and rivalry are all examined in this study. To accommodate ship owners, the SRF business, and the government in carrying out ship recycling, the results of this study are a reference for formulating specific regulations for the SRF cluster. This research found that Kamal and Bojonegara are viable for the SRF cluster.
Genome-Wide Analysis of Barley bHLH Transcription Factors and the Functional Characterization of HvbHLH56 in Low Nitrogen Tolerance in Arabidopsis

Improvement of low nitrogen (LN) tolerance or nitrogen use efficiency (NUE) in crops is imperative for environment-friendly agriculture development. The basic helix-loop-helix (bHLH) transcription factors are involved in multiple abiotic stresses and are suitable as candidate genes for improving LN tolerance. Few studies were performed on the characterization of the HvbHLH gene family and their function in response to LN stress in barley. In this study, 103 HvbHLH genes were identified through genome-wide analysis. HvbHLH proteins were classified into 20 subfamilies based on phylogenetic analysis in barley, which was supported by conserved motifs and gene structure analysis. The stress-related cis-element analysis in the promoters showed that HvbHLHs are probably involved in multiple stress responses. By phylogenetic analysis of HvbHLHs and bHLHs in other plants, some HvbHLHs were predicted to play roles in response to nutrition deficiency stress. Furthermore, at least 16 HvbHLHs were differentially expressed in two barley genotypes differing in LN tolerance under LN stress. Finally, overexpression of HvbHLH56 enhanced LN stress tolerance in transgenic Arabidopsis, suggesting it is an important regulator in LN stress response. The differentially expressed HvbHLHs identified herein may be valuable for the breeding of barley cultivars with LN tolerance.
Motion Artifacts Reduction for Noninvasive Hemodynamic Monitoring of Conscious Patients Using Electrical Impedance Tomography: A Preliminary Study

Electrical impedance tomography (EIT) can monitor the real-time hemodynamic state of a conscious and spontaneously breathing patient noninvasively. However, cardiac volume signal (CVS) extracted from EIT images has a small amplitude and is sensitive to motion artifacts (MAs). This study aimed to develop a new algorithm to reduce MAs from the CVS for more accurate heart rate (HR) and cardiac output (CO) monitoring in patients undergoing hemodialysis based on the source consistency between the electrocardiogram (ECG) and the CVS of heartbeats. Two signals were measured at different locations on the body through independent instruments and electrodes, but the frequency and phase were matched when no MAs occurred. A total of 36 measurements with 113 one-hour sub-datasets were collected from 14 patients. As the number of motions per hour (MI) increased over 30, the proposed algorithm had a correlation of 0.83 and a precision of 1.65 beats per minute (BPM) compared to the conventional statical algorithm of a correlation of 0.56 and a precision of 4.04 BPM. For CO monitoring, the precision and upper limit of the mean ∆CO were 3.41 and 2.82 L per minute (LPM), respectively, compared to 4.05 and 3.82 LPM for the statistical algorithm. The developed algorithm could reduce MAs and improve HR/CO monitoring accuracy and reliability by at least two times, particularly in high-motion environments.
Rapid and Sensitive Detection of Polycyclic Aromatic Hydrocarbons in Tea Leaves Using Magnetic Approach

A rapid and efficient method using an alkyl-functionalized magnetic nanoparticles-based extraction technique combined with Ultra-High Performance Liquid Chromatography was developed for the detection of trace amounts of polycyclic aromatic hydrocarbons in tea leaves. As a popular coating for chromatographic column packing materials, C18-alkyl has been demonstrated to be effective in separating polycyclic aromatic hydrocarbons. Additionally, the magnetism of the nanomaterials accelerates the extraction process while their high surface ratio enables desirable dispersity in the sample matrix. Meanwhile, the adsorbents can be washed and reused 30 times without compromising recovery, which greatly reduces the budget. The effects of various parameters were investigated and optimized, and the recoveries for five analytes were in the range of 84.8–105.4%. The RSD of intra-day and inter-day were below 11.9% and 6.8%, respectively. The limits of detection and limits of quantification ranged from 1.69–9.97 ng g−1 and 5.12–30.21 ng g−1, indicating satisfactory sensitivity. Thus, the proposed methodology is rapid, highly efficient, and economical, and it expands the application of magnetic cleanup approaches in complex food matrices.
The impact of propranolol on the growth and development of children with proliferative infantile hemangioma during treatment

Oral propranolol has not been shown to impact physical development, such as weight and height. The impact of children’s intellectual development has received relatively little attention from researchers. The effects of propranolol on the growth and development of children with proliferative infantile hemangiomas during treatment were analyzed retrospectively. The children with infantile hemangioma treated with oral propranolol in the Department of Burn and Plastic Surgery, Fuzhou Children’s Hospital of Fujian Province, from February 2017 to May 2022 were analyzed. A uniform therapeutic regimen was applied, including assessment, treatment, and follow-up. The assessment included physical development and intellectual development indices. The physical development indices were height and weight. Neuropsychological assessment uses developmental quotient (DQ) to assess intelligence development. The DQs on months 3, 6, and 9 posttreatment were compared to the pretreatment. Wilcoxon rank sum test of paired samples was used for height and weight. The developmental quotient was determined by paired t test. P < . 05 indicated significant difference. A total of 51 patients were enrolled. All children completed the treatment successfully, without severe adverse drug reactions leading to treatment discontinuation. There was no significant difference in height and weight before and after treatment (P > .05). No significant difference was detected in DQ 3 months posttreatment and pretreatment (P = .19), while it decreased at 6 and 9 months posttreatment (P < .05). Oral propranolol does not have an impact on physical development (height and weight). No short-term effect was found on intellectual development, but a decrease was noted over 6 months, which needs to be investigated further.
Sustainable Strategies for Increasing Legume Consumption: Culinary and Educational Approaches

Legumes are nutrient-dense crops with health-promoting benefits. However, several barriers are associated with their consumption. Emerging issues including food neophobic tendencies or taboos, unclear dietary guidelines on legume consumption, health concerns, and socio-economic reasons, as well as long cooking procedures, adversely affect legume consumption frequency. Pre-treatment methods, including soaking, sprouting, and pulse electric field technology, are effective in reducing the alpha-oligosaccharides and other anti-nutritional factors, eventually lowering cooking time for legumes. Extrusion technology used for innovative development of legume-enriched products, including snacks, breakfast cereals and puffs, baking and pasta, represents a strategic way to promote legume consumption. Culinary skills such as legume salads, legume sprouts, stews, soups, hummus, and the development of homemade cake recipes using legume flour could represent effective ways to promote legume consumption. This review aims to highlight the nutritional and health effects associated with legume consumption, and strategies to improve their digestibility and nutritional profile. Additionally, proper educational and culinary approaches aimed to improve legumes intake are discussed.
Optimum Contact Configurations for Quasi-One-Dimensional Phosphorene Nanodevices

We employ atomistic quantum transport simulations based on non-equilibrium Green’s function (NEGF) formalism of quasi-one-dimensional (quasi-1D) phosphorene, or phosphorene nanoribbons (PNRs), to explore routes towards minimizing contact resistance (RC) in devices based on such nanostructures. The impact of PNR width scaling from ~5.5 nm down to ~0.5 nm, different hybrid edge-and-top metal contact configurations, and various metal–channel interaction strengths on the transfer length and RC is studied in detail. We demonstrate that optimum metals and top-contact lengths exist and depend on PNR width, which is a consequence of resonant transport and broadening effects. We find that moderately interacting metals and nearly edge contacts are optimum only for wider PNRs and phosphorene, providing a minimum RC of ~280 Ωμm. Surprisingly, ultra-narrow PNRs benefit from weakly interacting metals combined with long top contacts that lead to an added RC of only ~2 Ωμm in the 0.49 nm wide quasi-1D phosphorene nanodevice.
On Some Necessary Conditions of Boolean Functions to Resist Algebraic Attacks

In this thesis we discuss certain properties of Boolean functions that are necessary for resistance against algebraic and fast algebraic attacks. A Boolean function f(x1, . . . , xn) on n variables may be described as a multivariate polynomial over GF (2) and it is well known that its algebraic degree d should not be low if it has to be used as a primitive in a well designed cryptosystem. Recently, it has been noted that a necessary condition in resisting algebraic attack is as follows: the function f should not have a relation fg = h, where g, h are nonzero n-variable Boolean functions of low degrees. This condition boils down to the situation that the function f should not have relations like fh1 = 0 or (1 + f)h2 = 0, where h1, h2 are nonzero n-variable Boolean functions of low degrees. The function h1 (respectively h2) is called the annihilator of f (respectively 1 + f). The notation AIn(f) is used to denote the minimum degree of the annihilators of f or 1 + f . This is well known as “Algebraic Immunity” of the function f in literature. There are evidences that algebraic immunity is not a sufficient condition to resist against all kinds of algebraic attacks, but clearly it is one of the most important necessary conditions. The term “Annihilator Immunity” may be a more appropriate notation than “Algebraic Immunity”, but following the frequent use of the term “Algebraic Immunity” in currently available research materials, we use the term Algebraic Immunity in this thesis. It is known that AIn(f) ≤ dn2 e. Good nonlinearity is one of the most important properties of Boolean functions to be used in a cryptosystem. We present a fundamental relationship between the algebraic immunity and the nonlinearity of a Boolean function. We first relate the weight of a function with its algebraic immunity and then extend the result to show that if nl(f) d + 1 then nl(f) ≥ ∑d i=0 ( n i ) . Thus while choosing a function with good algebraic immunity, the nonlinearity of the function is lower bounded. The main idea (in proving these results) is based on solutions to a set of homogeneous linear equations. Using similar approach, given a Boolean function, we have also studied the number of linearly independent annihilators at the lowest possible degree. Further we have studied some existing constructions of cryptographically significant Boolean functions in terms of their algebraic immunity. As there was no known construction of Boolean function with maximum possible algebraic immunity, next we concentrate on that problem. So far, the attempt in designing Boolean functions with required algebraic immunity was only ad-hoc, i.e., the functions were designed keeping in mind the other cryptographic criteria, and then it has been checked whether the function can provide good algebraic immunity too. For the first time, we present a construction method to generate Boolean functions on n variables with highest possible
HIV and Hepatitis C Risk among Tajik Migrant Workers Who Inject Drugs in Moscow

The human immunodeficiency virus (HIV) epidemic in Eastern Europe and Central Asia continues to grow with most infections occurring in high-risk groups including people who inject drugs and their sexual partners. Labor migrants from this region who inject drugs while in Russia are at especially high HIV risk. Male Tajik migrant workers who inject drugs in Moscow (N = 420) were interviewed prior to a randomized trial of the Migrants’ Approached Self-Learning Intervention in HIV/AIDS (MASLIHAT) peer-education HIV-prevention intervention. Participants were interviewed about their sex and drug use behavior and tested for HIV and hepatitis C (HCV) prior to the intervention. Only 17% had ever been tested for HIV. Over half of the men reported injecting with a previously used syringe in the past month, and substantial proportions reported risky sexual behavior. Prevalence rates of HIV (6.8%) and HCV (2.9%) were elevated, although lower than expected when compared to estimates of prevalence among people who inject drugs at the national level in Tajikistan. Risk behavior in diaspora varied across the men’s regional area of origin in Tajikistan and occupation in Moscow, with HIV prevalence rates highest among those working at the bazaars. Evidence-based prevention approaches and messaging that specifically address the drug- and sex-related risk behavior of migrants with varying backgrounds are needed.
Methods of postural analysis in connection with the stomatognathic system. A systematic review

This systematic review aimed to identify the main tools used to analyze the relationship between the postural and stomatognathic systems. The study followed the PRISMA guidelines, and data were collected from Science Direct and PubMed databases to identify articles published until December 2022. After applying inclusion and exclusion criteria, 26 articles were selected from the initial 903 articles. The selected articles were full-text studies in English or Romanian, examining the relationship between dental occlusion and posture, measuring postural parameters using various tools, implementing occlusal changes, evaluating patients with permanent dentition, or analyzing the connection between occlusion and posture in a unidirectional manner. The findings indicate that orthognathic surgery and orthodontic mouthguards can significantly enhance postural balance and athletic performance. In addition, 63% of the studies concluded that varying modifications and occlusal conditions impact posture. Notable differences exist concerning posture and Angle dental occlusion classes, and different occlusal devices used to simulate malocclusion can affect patients' postural systems in response to external stimuli. The stabilometry platform is the predominant method for measuring postural parameters; however, other researchers have employed raster stereography, photogrammetry, mobile phone apps, and the Fukuda-Unterberger test. Consequently, interventions targeting the stomatognathic system should consider potential variations in the postural system.
A Low-Carbon and Economic Dispatch Strategy for a Multi-Microgrid Based on a Meteorological Classification to Handle the Uncertainty of Wind Power

In a modern power system, reducing carbon emissions has become a significant goal in mitigating the impact of global warming. Therefore, renewable energy sources, particularly wind-power generation, have been extensively implemented in the system. Despite the advantages of wind power, its uncertainty and randomness lead to critical security, stability, and economic issues in the power system. Recently, multi-microgrid systems (MMGSs) have been considered as a suitable wind-power deployment candidate. Although wind power can be efficiently utilized by MMGSs, uncertainty and randomness still have a significant impact on the dispatching and operation of the system. Therefore, to address the wind power uncertainty issue and achieve an optimal dispatching strategy for MMGSs, this paper presents an adjustable robust optimization (ARO) model based on meteorological clustering. Firstly, the maximum relevance minimum redundancy (MRMR) method and the CURE clustering algorithm are employed for meteorological classification in order to better identify wind patterns. Secondly, a conditional generative adversarial network (CGAN) is adopted to enrich the wind-power datasets with different meteorological patterns, resulting in the construction of ambiguity sets. Thirdly, the uncertainty sets that are finally employed by the ARO framework to establish a two-stage cooperative dispatching model for MMGS can be derived from the ambiguity sets. Additionally, stepped carbon trading is introduced to control the carbon emissions of MMGSs. Finally, the alternative direction method of multipliers (ADMM) and the column and constraint generation (C&CG) algorithm are adopted to achieve a decentralized solution for the dispatching model of MMGSs. Case studies indicate that the presented model has a great performance in improving the wind-power description accuracy, increasing cost efficiency, and reducing system carbon emissions. However, the case studies also report that the approach consumes a relative long running time. Therefore, in future research, the solution algorithm will be further improved for the purpose of raising the efficiency of the solution.