Miracle-dz/UniFAR-FTUs huggingface dataset:
Large seasonal changes in the recharge of seawater in a subterranean estuary revealed by a radon tracer

Activities of radon (222Rn) in groundwater were continuously monitored in a saline aquifer from September 2010 to July 2011. The activities of 222Rn ranged from 200 to 4300 Bq m−3, with a large seasonal variation. Because the activity of 222Rn in seawater is low, 222Rn in saline groundwater must be produced in the aquifer from radium (226Ra) in rocks and sediments. The 222Rn activities were higher in the warm‐dry seasons (September–November 2010 and April–May 2011) when the saline aquifer was stable. In contrast, the lowest 222Rn activities were observed in the cold‐dry season (December 2010 and January–March 2011), because of the effective exchange between groundwater and seawater. In addition, sudden decreases of 222Rn activities coincided with episodic drops in groundwater temperatures. These results reveal that lower seawater temperature in winter may result in density‐driven seawater intrusion. During the wet season (June–July 2011), 222Rn activities were more clearly affected by semi‐monthly and diurnal tidal pumping, showing higher 222Rn activities during low and spring tides. Such a tidal effect was not clearly observed during the warm‐dry and cold‐dry seasons. This result implies that the residence time of SGD in coastal zones is significantly affected by seasonal changes in driving forces such as tidal pumping and seawater intrusion. Copyright © 2016 John Wiley & Sons, Ltd.
Construction of millimeter-scale vascularized engineered myocardial tissue using a mixed gel

Abstract Engineering myocardium has shown great clinal potential for repairing permanent myocardial injury. However, the lack of perfusing blood vessels and difficulties in preparing a thick-engineered myocardium result in its limited clinical use. We prepared a mixed gel containing fibrin (5 mg/ml) and collagen I (0.2 mg/ml) and verified that human umbilical vein endothelial cells (HUVECs) and human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) could form microvascular lumens and myocardial cell clusters by harnessing the low-hardness and hyperelastic characteristics of fibrin. hiPSC-CMs and HUVECs in the mixed gel formed self-organized cell clusters, which were then cultured in different media using a three-phase approach. The successfully constructed vascularized engineered myocardial tissue had a spherical structure and final diameter of 1–2 mm. The tissue exhibited autonomous beats that occurred at a frequency similar to a normal human heart rate. The internal microvascular lumen could be maintained for 6 weeks and showed good results during preliminary surface re-vascularization in vitro and vascular remodeling in vivo. In summary, we propose a simple method for constructing vascularized engineered myocardial tissue, through phased cultivation that does not rely on high-end manufacturing equipment and cutting-edge preparation techniques. The constructed tissue has potential value for clinical use after preliminary evaluation.
Tools and Environments

Powered by TCPDF (www.tcpdf.org) This material is protected by copyright and other intellectual property rights, and duplication or sale of all or part of any of the repository collections is not permitted, except that material may be duplicated by you for your research use or educational purposes in electronic or print form. You must obtain permission for any other use. Electronic or print copies may not be offered, whether for sale or otherwise to anyone who is not an authorised user. Malmi, Lauri; Utting, Ian; Ko, Andrew J.
A Game-Theoretic Approach to Cross-Layer Security Decision-Making in Industrial Cyber-Physical Systems

Current security measures in industrial cyber-physical systems (ICPS) lack the active decision capability to defend against highly-organized cyber-attacks. In this paper, a security decision-making approach based on stochastic game model is proposed to characterize the interaction between attackers and defenders in ICPSs and generate optimal defense strategies to minimize system losses. The major distinction of this approach is that it presents a practical way to build a cross-layer security game model for ICPSs by means of quantitative vulnerability analysis and time-based unified payoff quantification. A case study on a hardware-in-the-loop simulation testbed is carried out to demonstrate the feasibility of the proposed approach.
The Liuqu Conglomerate, southern Tibet: Early Miocene basin development related to deformation within the Great Counter Thrust system

The Liuqu basin formed during the early Miocene between ophiolitic melanges (to the south) and uplifted Cretaceous forearc deposits (to the north) along a central, 150-km-long segment of the India-Asia suture zone in southern Tibet. Sedimentological analysis shows the Liuqu Conglomerate to be composed of mixed fluvial and sediment-gravity flow lithofacies assemblages locally interbedded with mature paleosols. We interpret the Liuqu Conglomerate as coarse-grained fluvial and alluvial-fan deposits. Structural analysis indicates that the Liuqu Conglomerate was deposited in a contractional setting. Paleocurrent and provenance data demonstrate that sediment was transported north-northwest from the hanging wall of a coeval thrust fault system along the southern limit of Liuqu outcrops. Detrital zircon U-Pb ages (and Hf[ t ] isotope ratios) cluster around 80–110 Ma (eHf[t] = −23.5–14.6), 120–135 Ma (eHf[t] = −12.6–13.1), 150–170 Ma (eHf[t] = −14.1–14.7), 500–600 Ma (eHf[t] = −26–3.4), and 1100–1200 Ma (eHf[t] = −27.6–2.9), requiring input from both Gangdese and melange sources. Asian zircons were recycled northward after being incorporated into accretionary melanges along the southern Asian margin prior to India-Asia collision. The age of the Liuqu Conglomerate is still somewhat uncertain, but new chronologic data, including biotite 40Ar/39Ar data, detrital zircon fission-track analyses, and δ13C compositions of soil carbonates, all converge on ca. 20–19 Ma as the most probable age. Together, these results indicate that part of the north-to-south sediment transport system that existed prior to India-Asia collision and into the Eocene was reversed by ca. 20 Ma. The Liuqu Conglomerate may represent deposits associated with the paleo–Yarlung River.
Annotated checklist of millipede of the infraclass Pentazonia (Myriapoda: Diplopoda) of Indonesia

A comprehensive checklist of millipedes of the infraclass Pentazonia is compiled for Indonesia. A total of 80 species assigned to 11 genera, three families and three orders has so far been recorded. Two genera are remarkably species-rich: Castanotherium (36 species) and Hyleoglomeris (15 species). Three genera, Malayomeris, Rajasphaera, Leptoprotopus are monotypic. Most of the species are endemic, recorded only in Indonesia (71 species).
Methodology of Automatic Relief Shading Map Making Based on Global Mapper——Taking Xi'an Region (I-49) as an Example

Based on mapping software such as Global Mapper,ERDAS and MicroDEM etc.,the relief shading maps can be automatically made by means of DEM data.In accordance with the basic theory of relief shading,taking Xi'an region(sheet number Ⅰ-49,national standard division range 1∶1 000 000 geomorphologic maps) as an example,this paper presents the whole process of making relief shading using Global Mapper in computer.The key technology of relief shading is the main study content.The relationship between the effect of relief shading and the parameters is analyzed,and the rationality of various parameters setting in the Global Mapper is illustrated.The setting of light direction,environmental lighting and vertical exaggeration coefficient should perfectly represent not only the combination of the whole effect,but also the partial texture of the geomorphologic shading map.Therefore,the basic rules of relief shading map production and the geomorphology features of the study area before relief shading designing should be understood.In order to make colorful relief shading map,the elevation of the study area must be classified according to regional geomorphology features,and the color value of every levels is completed by hierarchical color design.Either evident regularity,or color and abundance of regional geomorphology were reflected in the relief shading map.Finally,the result maps need to be local fine adjusted in the PHOTOSHOP software.
Genetic differentiation of the indigenous Norway Spruce (Picea abies (L.) Karst) populations in Slovenia investigated by means of isoenzyme gene markers

Genetic differentiation of 22 indigenous Norway spruce (Picea abies (L.) Karst) populations from Slovenia and 4 from Croatia has been investigated by means of isoenzyme gene markers. The degree of differentiation among populations has been measured with genetic distances proposed by Gregorius (1974) for 15 polymorphic gene loci. Multilocus estimates of genetic distancesrange between 0.021 and 0.073 (in Slovenia up to 0.063). Norway spruce populations did not show a strong genetic differentiation by isozymes. The results of hierarchical classification indicated a geographically dependent pooling of populations into two distinct groups: Alpine group including Trnovski gozd and Central Dinaric group, with the two groups overlapping in the Snežnik area.
Power-Law flood frequency analysis of selected Queensland stream gauges

Flood Frequency Analysis is key to the prediction of frequency and magnitude of extreme flood events in given catchments. Floods can cause millions of dollars damage to communities and since it is important to have adequate flood protection measures, it is desirable to obtain accurate estimates of flood recurrence. The aim of this project is to investigate the suitability of the Power Law frequency model as a more accurate way of the peak discharges of flood events. Using two goodness of fit tests, the Chi-Squared test and the R-Squared test, the Power Law relationship has been tested against the more conventional methods used in Australian, the Log Pearson type 3 distribution and the exponential distribution for ten stream gauge stations located throughout Queensland. The results of the analysis of the ten stream gauges found that generally the Log Pearson type 3 distribution was more accurate in predicting the peak discharges of the observed historical flows for sites of which the floods are expected to occur in intervals greater than ten years. The Power Law frequency model however produces a more conservative estimate for the return period of the larger floods and hence increasing the estimated likelihood of severe floods. Therefore the use of the Power Law relationship as procedure for flood frequency analysis for the extreme events would create more conservative infrastructure designs and land use restrictions.
Sistema colaborativo de detección y seguimiento deanomalías mediante visión por computador

En este proyecto se realiza el diseno e implementacion de un sistema que detecta anomalias en las entradas de entornos controlados. Para ello, se hace uso de las ultimas tecnicas en vision por computador y se avisa visual y auditivamente, mediante un sistema hardware que recibe senales del ordenador al que esta conectado. Se marca y fotografia, a una o varias personas, que cometen una infraccion en las entradas de un establecimiento, vigilado con sistemas de video. Las imagenes se almacenan en las carpetas correspondientes. El sistema disenado es colaborativo, por lo tanto, las camaras que intervienen, se comunican entre ellas a traves de estructuras de datos con el objetivo de intercambiar informacion. Ademas, se utiliza conexion inalambrica desde un dispositivo movil para obtener una vision global del entorno desde cualquier lugar del mundo. La aplicacion se desarrolla en el entorno MATLAB, que permite un tratamiento de la senal de imagen apropiado para el presente proyecto. Asimismo, se proporciona al usuario una interfaz grafica con la que interactuar de manera sencilla, evitando asi, el cambio de parametros en la estructura interna del programa cuando se quiere variar el entorno o el tipo de adquisicion de datos. El lenguaje que se escoge facilita la ejecucion en distintos sistemas operativos, incluyendo Windows o iOS y, de esta manera, se proporciona flexibilidad. ABSTRACT. This project studies the design and implementation of a system that detects any anomalies on the entrances to controlled environments. To this end, it is necessary the use of last techniques in computer vision in order to notify visually and aurally, by a hardware system which receives signs from the computer it is connected to. One or more people that commit an infringement while entering into a secured environment, with video systems, are marked and photographed and those images are stored in their belonging file folder. This is a collaborative design system, therefore, every involved camera communicates among themselves through data structures with the purpose of exchanging information. Furthermore, to obtain a global environment vision from any place in the world it uses a mobile wireless connection. The application is developed in MATLAB environment because it allows an appropriate treatment of the image signal for this project. In addition, the user is given a graphical interface to easily interact, avoiding with this, changing any parameters on the program’s intern structure, when it requires modifying the environment or the data type acquisition. The chosen language eases its execution in different operating systems, including Windows or iOS, providing flexibility.
Estimating the Heterogeneity Variance in a Random-Effects Meta-Analysis

In a meta-analysis, differences in the design and conduct of studies may cause variation in effects beyond what is expected from chance alone. This additional variation is commonly known as heterogeneity, which is incorporated into a random-effects model. The heterogeneity variance parameter in this model is commonly estimated by the DerSimonian-Laird method, despite being shown to produce negatively biased estimates in simulated data. Many other methods have been proposed, but there has been less research into their properties. This thesis compares all methods to estimate the heterogeneity variance in both empirical and simulated meta-analysis data. First, methods are compared in 12,894 empirical meta-analyses from the Cochrane Database of Systematic Reviews (CDSR). These results showed high discordance in estimates of the heterogeneity variance between methods, so investigating their properties in simulated meta-analysis data is worthwhile. A systematic review of relevant simulation studies was then conducted and identified 12 studies, but there was little consensus between them and conclusions could only be considered tentative. A new simulation study was conducted in collaboration with other statisticians. Results confirmed that the DerSimonian-Laird method is negatively biased in scenarios where within-study variances are imprecise and/or biased. On the basis of these results, the REML approach to heterogeneity variance estimation is recommended. A secondary analysis combines simulated and empirical meta-analysis data and shows all methods usually have poor properties in practice; only marginal improvements are possible using REML. In conclusion, caution is advised when interpreting estimates of the heterogeneity variance and confidence intervals should always be presented to express its uncertainty. More promisingly, the Hartung-Knapp confidence interval method is robust to poor heterogeneity variance estimates, so sensitivity analysis is not usually required for inference on the mean effect.
An assessment of the Pull between Landuse and Landcover in Southwestern Nigeria and the Ensuing Environmental Impacts

SUMMARY The entire land mass area of the earth (removing the desert areas, water bodies, exposed rock surfaces, built-up areas and other significant non-vegetation cover surfaces) could be imagined to have been originally covered by vegetation when human population was small and the global environment was in its “ideal” state. As population increased, coupled with technological advancement, the quest for economic development gained ground and the demand for forest and other vegetation resources kept rising. Thus landuse for different purposes emerged and the landscape as well as the original vegetation cover continued to be modified. This paper examined the pull between landuse and landcover (LULC) in our contemporary time with a view to highlighting some of the attendant environmental consequences, using satellite multi-temporal datasets of the study area. The computed average rate of deforestation of the selected forest reserves in the study area is about 2.55% per year while the average rate of township expansion is about 2.9% per year. The vegetation landscape has been considerably modified over the years showing different agro-forests, exotic plantations, arable crop lands, forest reserves and cultural centres as dominant landuses. The environmental consequences (including urban land erosion, flooding, increase in the extent of impervious surfaces, environmental pollution, biodiversity loss, global warming, rainfall regime variability, unstable dry/wet season period, low crop yield, etc.) have been highlighted. Some suggestions have been put forward to weaken the pull between LU LC for optimum environmental and economic developments.
H2S-Synthesizing Enzymes Are Putative Determinants in Lung Cancer Management toward Personalized Medicine

Lung cancer is a lethal disease with no truly efficient therapeutic management despite the progresses, and metabolic profiling can be a way of stratifying patients who may benefit from new therapies. The present study is dedicated to profiling cysteine metabolic pathways in NSCLC cell lines and tumor samples. This was carried out by analyzing hydrogen sulfide (H2S) and ATP levels, examining mRNA and protein expression patterns of cysteine catabolic enzymes and transporters, and conducting metabolomics analysis using nuclear magnetic resonance (NMR) spectroscopy. Selenium–chrysin (SeChry) was tested as a therapeutic alternative with the aim of having an effect on cysteine catabolism and showed promising results. NSCLC cell lines presented different cysteine metabolic patterns, with A549 and H292 presenting a higher reliance on cystathionine β-synthase (CBS) and cystathionine γ-lyase (CSE) to maintain H2S levels, while the PC-9 cell line presented an adaptive behavior based on the use of mercaptopyruvate sulfurtransferase (MST) and cysteine dioxygenase (CDO1), both contributing to the role of cysteine as a pyruvate source. The analyses of human lung tumor samples corroborated this variability in profiles, meaning that the expression of certain genes may be informative in defining prognosis and new targets. Heterogeneity points out individual profiles, and the identification of new targets among metabolic players is a step forward in cancer management toward personalized medicine.
Biodiversity Conservation in Arid Environments under Climate Change

Aim Compare the performance of continental and regional models in predicting species distributions at range margins. Selection of study area extent, resolution and threshold affects ecological model predictions. At range margins of species distribution, local populations may be restricted to suboptimal environments distinct from the species’ global range, which may be missed by continental models. Location Africa and West Africa. Methods We analysed differences in predicted distributions at range margins of three widespread African species that in West Africa occur in peripheral populations restricted to particular habitats. We made comparisons between models built with data from the complete and restricted range of species’ distributions (Africa and West Africa, respectively), with coarse and fine resolutions (10x10km and 1x1km, respectively), and classified with three thresholds of species presence (minimum training presence, tenth percentile training presence and maximum training sensitivity plus specificity thresholds). We predicted the species' distributions and quantified environmental variable importance and profile using Maximum Entropy, and estimated niche breadth parameters with Ecological Niche Factor Analysis. Results We found differences between model types in niche breadth estimates and in also response curves of the most important variables, suggesting that fine resolution models are more accurate at selecting marginal habitats in West Africa than in Africa. The predictions of species distributions differed with model extent, resolution and threshold analysed. Models built with the complete species environmental range and with coarse resolution tended to overestimate species distributions at the edge but accuracy increased when more restrictive thresholds were used. In West Africa, independently of the resolution, the threshold value was less important for maximising agreement between predicted probabilities and observed distribution. Main conclusions At range margins of species distributions, regional models with precise data and conservative thresholds should be preferred over continental models with coarser resolution to identify suitable areas for peripheral populations.
Visibilidade de revistas científicas: um estudo no Portal de Periódicos Científicos da Universidade Federal do Rio Grande do Sul Visibility of scientific journals: A study based on the Website of Scientific Journals at Universidade Federal do Rio Grande do Sul

Abstract The study addresses the visibility of electronic scientific journals, as well as the characteristics that promote, especially focusing on thosehosted on the Portal of Scientific Journals of the Universidade Federal do Rio Grande do Sul . The study assesses the degree of visibilityof these journals on the Internet by means of their presence in information sources. The theoretical reference addresses the followingthemes: scientific communication; scientific journals; visibility and searchability; information sources on portal; bibliographic databasesand open access. This is a descriptive and exploratory study that combines qualitative and quantitative data. The corpus of research wascomposed of 34 titles. Essential information about the journals was collected, giving emphasis to the characteristics that promote theirvisibility. It was found that Human Sciences is the area with the greatest number of journals at the University, 29.4% of all publications.Open access is adopted by all journals in the sample. Once the information sources had been mapped, it was found that the majority ofjournals appear in the information source Latin American Periodicals Tables of Contents, followed by Latindex. Despite the limited presenceof the journals in international information sources, it was concluded that the journals hosted on the Website of Scientific Journals seekto adapt to characteristics that promote their visibility. The study suggests a number of new studies, deepens the analyses, and addressesother themes related to visibility and, especially, bibliometric studies.Keywords
Effective stress in rock

This paper looks at what is the meaning of effective stress in rock and how it is measured. The paper examines the field measurement of stress in intact and jointed systems including fluid pressure and how it acts within the matrix and joints. How the fluid pressure acts varies between rock types and structure. The processes of stress measurement by overcoring and hydrofracture are considered and the benefits and deficiencies of each system discussed. The determination of Biot’s poroelastic coefficient and how this relates to a fractured system are discussed. The importance of effective stress on failures within rock are considered. Keywords: stress, fluid, pressure, rock, effective, poroelastic, joints, Biot