Miracle-dz/UniFAR-FTUs huggingface dataset:
Current and Emerging Endovascular and Neurocritical Care Management Strategies in Large-Core Ischemic Stroke

The volume of infarcted tissue in patients with ischemic stroke is consistently associated with increased morbidity and mortality. Initial studies of endovascular thrombectomy for large-vessel occlusion excluded patients with established large-core infarcts, even when large volumes of salvageable brain tissue were present, due to the high risk of hemorrhagic transformation and reperfusion injury. However, recent retrospective and prospective studies have shown improved outcomes with endovascular thrombectomy, and several clinical trials were recently published to evaluate the efficacy of endovascular management of patients presenting with large-core infarcts. With or without thrombectomy, patients with large-core infarcts remain at high risk of in-hospital complications such as hemorrhagic transformation, malignant cerebral edema, seizures, and others. Expert neurocritical care management is necessary to optimize blood pressure control, mitigate secondary brain injury, manage cerebral edema and elevated intracranial pressure, and implement various neuroprotective measures. Herein, we present an overview of the current and emerging evidence pertaining to endovascular treatment for large-core infarcts, recent advances in neurocritical care strategies, and their impact on optimizing patient outcomes.
Assessment of human health effects associated with exposure to indoor air pollution

Indoor air pollution or exposure to indoor air pollutants is recognized as one of the major human health concerns. The quality of air inside homes, offices, schools or other private and public buildings is an essential determinant of healthy life and people’s well-being. WHO estimated that Indoor air pollution (IAP) causes approximately 2 million premature deaths in developing countries. IAP in dwelling areas is mainly due to emissions from cooking (biomass fuels), smoking, burning of mosquito coils, cigarettes, incense sticks etc. Smoke released from these activities contain significant amount of pollutants which includes particulate matter (PM), Polycyclic aromatic hydrocarbons (PAH), Carbon monoxide (CO) and other toxic gases which are identified as potential carcinogens. The emissions released far exceed the recommended levels prescribed by the WHO and EPA. This paper attempts to assess the possible health risks of indoor air pollution particularly in the Indian context. The study also discusses the interventions to reduce IAP and associated health effects.
Estimating 3D-trajectories from Monocular Video Sequences

Tracking a moving object and reconstructing its trajectory can be done with a stereo camera system, since the two cameras enable depth vision. However, such a system would not work if one of the cameras fails to detect the object. If that happens, it would be beneficial if the system could still use the functioning camera to make an approximate trajectory reconstruction.In this study, I have investigated how past observations from a stereo system can be used to recreate trajectories when video from only one of the cameras is available. Several approaches have been implemented and tested, with varying results. The best method was found to be a nearest neighbors-search optimized by a Kalman filter. On a test set with 10000 golf shots, the algorithm was able to create estimations which on average differed around 3.5 meters from the correct trajectory, with better results for trajec-tories originating close to the camera.
Assessing a relation between composition of luminal and tissue microbiota and cErvical intraepithelial changes

The incidence of cervical cancer (CC) in Russia remains at a high level and ranks fourth among all cancers. CC is preceded by mild, moderate, and severe cervical intraepithelial neoplasia. Human papillomavirus (HPV) is known to be the main cause for its development being responsible for 99% cancer cases. Despite HPV infection, the oncological process occurs only under certain conditions. There are risk factors that indirectly affect the course and emergence of cervical dysplasia. In recent years, the role of cervico-vaginal microbiome for onset and progression of this pathology has been actively discussed. Many studies evidence that dysbiosis along with cervical intraepithelial dysplasia is associated with increased HPV viral load, additionally allowing to clarify a role of specific microorganisms. Despite the knowledge rapidly accumulating about the nature of vaginal microbiome in cervical precancerous processes, the level of its impact on disease course has not been fully investigated and is of great interest. Identification of microorganisms that affect emergence and progression of this pathology will allow to prevent and apply select approach to treatment of dysbiosis. The aim of our study was to identify a relation between cervical tissue and luminal culturome and severe cervical intraepithelial neoplasia. The study evaluated the microbiota of cervical and cervical canal mucosa biopsy in patients with cervical intraepithelial changes. According to the study results, the Streptococcus genus representatives were significantly more frequent in cervical biopsy specimens in severe dysplasia vs. no cervical intraepithelial changes, whereas cervical canal cultures provided comparable data. Bacteria from the Corynebacterium genus were found in cervical biopsy specimens 3 times more often than in smear from the cervical canal mucous membrane. The microbiota from cervical and cervical canal biopsy specimens differ qualitatively and quantitatively particularly regarding prevalence of Streptococcus spp. representatives being more common in patients with cervical dysplasia. Corynebacterium spp. were detected more often in cervical biopsy specimens than in cervical canal smears. Thus, the method of collecting biological material has a great influence on final results.
ANTESEDEN DAN KONSEKUEN DARI KINERJA RANTAI PASOK TERPADU PADA LAYANAN RUMAH SAKIT SWASTA

Tujuan penelitian ini adalah untuk menganalisis pengaruh hubungan karyawan, pertukaran pengetahuan, fleksibilitas rantai pasok, orientasi organisasi, kinerja rantai pasok terpadu terhadap fokus pasien/pelanggan. Data diperoleh dengan menyebarkan kuesioner secara online kepada karyawan medis dari rumah sakit swasta Mitra Keluarga Group. Sampel yang digunakan pada penelitian ini sebanyak 250 responden. Metode analisis data yang digunakan pada penelitian ini untuk menganalisis pengaruh antar variabel-variabel yang dimiliki menggunakan metode Structural Equation Model (SEM) dengan bantuan software AMOS 24. Hasil penelitian ini menyimpulkan hubungan karyawan, pertukaran pengetahuan, fleksibilitas rantai pasok, orientasi organisasi berpengaruh positif terhadap kinerja rantai pasok terpadu, kinerja rantai pasok terpadu berpengaruh positif terhadap fokus pasien/pelanggan.
Exploration of the Need for Integration of Cervical Cancer Information into Postnatal Services at Primary Health Care Centers in Ibadan Nigeria

Background: Cervical cancer (CC) is a preventable disease yet it is one of the leading causes of death, especially in low-income countries. In Nigeria, information on CC is yet to be part of routine health talk at Postnatal Clinics (PNC) at the Primary Health Care (PHC) level. The PNC would however have been a good avenue to reach women at risk of CC. This study explored health care workers (HCWs)’ willingness to integrate CCS services (CCSS), and women’s readiness to uptake the services at PHCs in Ibadan, Nigeria. Method: A qualitative study design was employed in this study. Data were collected through four sessions of Focus Group Discussions (FGDs) among the women attending PNC, and 20 Key Informant Interviews (KIIs) for health workers in PHC facilities. The Atlas.ti software, version 8 was used for the analysis. Thematic contents from the study were presented as quotes and streams of thoughts. Results: Information on CCS is currently excluded from the list of PNC activities such that most women have never heard of the need for CCS. They were interested in receiving CCS information and services. Women pleaded for the integration of CCS information in PHC clinic activities but preferably in a free or subsidized format in order to encourage utilization of the services. Challenges identified were mainly a shortage of manpower and a lack of training on CCS. Conclusion: Health workers were willing to integrate CCS services in PHC activities, however, recommended recruitment of more hands to ensure effective service delivery in line with National health policy on PHC in Nigeria.
Extraction of cross sections from digital elevation model for one‐dimensional dam‐break wave propagation in mountain valleys

Shallow Water Equations (SWE) provide a fundamental component for the quantification and mapping of hydraulic hazard. In steep mountain valleys, the use of one‐dimensional SWE (also known as St. Venant Equations, SVE) is often legitimate and computationally competitive against two‐dimensional solvers. However, in the same environment, the solution of SVE is hindered by the need of an accurate bathymetric reconstruction, which implies a number of cross sections which cannot be readily acquired by conventional field surveys. On the other hand, Digital Elevation Models (DEM) with resolution adequate for studies of flood propagation are available in many areas of the world. In this paper, I propose to compute cross sections automatically by operating along the channel network derived from a valley's raster DEM, on the basis of algorithms that hitherto have been used for geomorphological and hydrological purposes. The extraction process can be refined by varying cross section inter‐distance and width, in order to prevent superimpositions that might occur due to the sinuosity of the thalweg and to better capture the valley's local topography. At the end of this process, the geometric functions needed by SVE solvers can be computed for each cross section. A software tool that implements the described algorithm is provided to the scientific community.
Attainment of the Health Outcomes by Implementing Educational Videos During the Final Part of the Physical Education Lesson

This study investigated the impact of educational video content in the final part of the PE lesson on students’ health literacy and their perceptions of the usefulness and satisfaction of PE lessons. The study included 160 students in grades 6 to 8 from an elementary school in Croatia, with an average age of 13.75 years, of which 93 (58%) were female. The experimental group (n=111) participated in the PE lessons with educational video content, while the control group (n=49) participated in the standard PE lesson. At the beginning and at the end of the research, both groups completed a theoretical written knowledge test on health literacy and a questionnaire to assess attitudes towards PE lessons. An ANCOVA was used to measure the impact of the experimental programme on post-intervention results while including initial results as a covariate. After the experiment, statistically significant differences were observed between the results of the experimental and control groups of students for Theoretical knowledge (9.90±0.29 vs. 8.33±0.43, F(1,159) = 8.998, p = 0.003) and Perception of the usefulness of PE lessons (2.93±0.06 vs 2.69±0.09, F(1,163) = 4.434, p = 0.037), while no statistically significant differences were observed for Satisfaction with PE lessons (2.95±0, 09 vs. 3.02±0.06, p = 0.553). The intervention positively affected students’ knowledge and perception of PE lessons without impairing their satisfaction, indicating that integrating educational video content into PE lessons connecting physical activity and health literacy is viable.
Anti-Hyperglycemic and Antioxidant Potentials of Some Bioactive Compounds Identified From The Methanolic Kernel Extract of Anacadium ocidentale in vitro and in silico Investigations

The phytochemical components of roasted kernel of cashew nut (Anacadium ocidentale), its antioxidant and anti-hyperglycemic potentials were investigated via in vitro and in silico. The roasted kernel of cashew nut was extracted in 95 % methanol. Using boron trifloride (10 % in 1-butanol), the extract was derivatized and the derivatized sample was analyzed using a Gas Chromatographic–Mass Spectrometry (GC-MS) method to establish its chemical constituents. Antioxidant potential was evaluated through 2, 2-diphenyl-1-picrylhydrazyl (DPPH•) and 2,2′-azino-bis-(3-ethyl benzothiazoline-6-sulphonic acid) (ABTS•+) radical scavenging assays. The anti-hyperglycemic potential of the crude methanol extract was investigated through α-glucosidase assay. The results of phytochemical screening revealed the presence of phytochemicals such as phenols, glycosides, alkaloids, steroids, carbohydrate, flavonoids and terpenoids. Total numbers of 20 phytochemicals belonging to different classes of natural products were identified by GC-MS analysis. Carbonic acid, dodecyl vinyl ester (45.9 %) was found to be the major compound. Other compounds like N- serylserine, D- fructose, 3-0-methyl, β- Amyrone, β- Amyrin, Lupeol and 9- octadecenoic acid were also identified. The methanol extract of roasted cashew kernel showed highest DPPH scavenging activity (IC50 10 ± 0.001 µg/mL) which is statistically similar to positive controls, vitamin C and rutin (IC50 = 4 ± 0.001 and 1 ± 0.0001 µg/mL) and also exhibited moderate ABTS scavenging activity (IC50 = 14 ± 0.001 µg/mL) which is statistically significant as compared to positive controls, vitamin C (IC50 = 13 ± 0.01 µg/mL) and rutin (IC50 = 16 ± 0.001 µg/mL) respectively. The result of enzyme inhibition assay showed that the extract possesses highest anti-hyperglycemic potential against α-glucosidase with IC50 value (0.00024 ± 0.00002 µg/mL) compared to standard drug acarbose (IC50 = 0.417 ±0.021 µg/mL). The in silico techniques comprising the molecular docking, bioactivity and toxicity studies provides insight into the inhibitory properties, structure-activity-relationship predictions and drug-likeliness activities of the identified compounds. The research reveals the bioactive components present in the roasted kernel of cashew nut that can be utilized for its antioxidant and anti-hyperglycemic properties. Hence consumption of roasted cashew kernel could be beneficial for the treatment of diabetes mellitus and prevention of oxidative stress-related degenerative disorders
Relationship between position of flux strips in arc zone of ultra-narrow gap and constricting arc

When flux strips applied to constrict arc have different relative positions with arc in ultra-narrow gap,flux strips can cause different constricting effects on arc,so the position of flux strips in the arc zone is the linchpin of constricting arc in time of ultra-narrow gap welding with flux strips constricting arc.By analyzing the position of flux strips in the arc zone,the results indicate only when three positional conditions are satisfied,flux strips can efficiently constrict arc,firstly flux strips need cling to sidewalls in the direction of radial of arc;secondly flux strips need proper action length in the direction of arc length;thirdly the tip of wire needs be located in the center of flux strips.Furthermore,under arc current exceeds 240 A,flux strips can easily cling to the surface of wire because of action of electromagnetic force,the position of flux strips in the direction of radial of arc can be located efficiently by supporting flux strips.
Single-Atom Catalysts for Selective Oxygen Reduction: Transition Metals in Uniform Carbon Nanospheres with High Loadings

Transition metal single-atom catalysts (SACs) in uniform carbon nanospheres have gained tremendous interest as electrocatalysts owing to their low cost, high activity, and excellent selectivity. However, their preparation typically involves complicated multistep processes that are not practical for industrial use. Herein, we report a facile one-pot method to produce atomically isolated metal atoms with high loadings in uniform carbon nanospheres without any templates or postsynthesis modifications. Specifically, we use a chemical confinement strategy to suppress the formation of metal nanoparticles by introducing ethylenediaminetetraacetic acid (EDTA) as a molecular barrier to spatially isolate the metal atoms and thus generate SACs. To demonstrate the versatility of this synthetic method, we produced SACs from multiple transition metals, including Fe, Co, Cu, and Ni, with loadings as high as 3.87 wt %. Among these catalytic materials, the Fe-based SACs showed remarkable catalytic activity toward the oxygen reduction reaction (ORR), achieving an onset and half-wave potential of 1.00 and 0.831 VRHE, respectively, comparable to that of commercial 20 wt % Pt/C. Significantly, we were able to steer the ORR selectivity toward either energy generation or hydrogen peroxide production by simply changing the transition metal in the EDTA-based precursor.
Construction of Taliban Image in Pakistan: Discourse Analysis of Editorials of Dawn and The News

The aim of this research study is to investigate as to how the image of Taliban is being constructed in the print media discourses. In the last couple of years, media in Pakistan widely covered the involvement of Taliban, fanning extremism in Pakistan, which, at present, forms a frame of reference in national context. The media coverage shows that the Taliban mostly carry negative images. They might have some positive gestures as well, but the overall image is clearly negative. Most of editorials in leading newspapers see Taliban behind growing extremism in the country. This paper discusses the difference of image building between two leading English language newspapers - The News and Dawn. The study describes the coverage pattern of the two distinct newspapers on Taliban and extremism. Editorials of these two Pakistani newspapers published from 1 st February 2009 to 31 st March 2009 were selected to study media construction of the image of Taliban in Pakistan. The rationales behind selecting these newspapers are: (1) both the English newspapers have a high circulation (2) both have distinct editorial policies. The paper concludes that media constructs a negative image of Taliban in the editorial discourses. The paper examines as to how the media constructs the image of Taliban and to what extent this portrayal forms derogatory and stereotypical frames of them. Concretely, this study focuses on the frame that has been applied by both the newspapers DAWN and The News while writing editorials on Taliban. These frames identify differences and similarities between the coverage of the two newspapers. The paper does speak of the stylistic features in editorials of both the newspapers.
Changes in the spatial patterns of avian migrations: Evidence, mechanisms and causes

Understanding the suite of environmental changes impacting migration and disentangling these from the dependencies between migratory stages is fundamental to understanding the drivers and mechanisms causing spatial shifts to migratory bird distributions. In this review, our objectives are to: (i) provide evidence of spatial change at all migratory stages, (ii) identify the key mechanisms driving change, (iii) discuss how anthropogenic change influences migratory patterns, (iv) highlight interdependencies between migratory stages and (v) offer a framework for understanding migratory pattern changes.
Cold Fog Amongst Complex Terrain

Cold fog forms via various thermodynamic, dynamic, and microphysical processes when the air temperature is less than 0°C. It occurs frequently during the cold season in the western United States yet is challenging to detect using standard observations and very difficult to predict. The Cold Fog Amongst Complex Terrain (CFACT) project was conceived to investigate the life cycle of cold fog in mountain valleys. The overarching goals of the CFACT project are to 1) investigate the lifecycle of cold-fog events over complex terrain with the latest observation technology, 2) improve microphysical parameterizations and visibility algorithms used in numerical weather prediction (NWP) models, and 3) develop data assimilation and analysis methods for current and next-generation (e.g., sub-kilometer scale) NWP models. The CFACT field campaign took place in Heber Valley, Utah, during January and February 2022, with support from NSF’s Lower Atmospheric Observing Facilities (managed by NCAR’s Earth Observing Laboratory), the University of Utah, and Ontario Technical University. A network of ground-based and aerial in situ instruments and remote sensing platforms were used to obtain comprehensive measurements of thermodynamic profiles, cloud microphysics, aerosol properties, and environmental dynamics. Nine intensive observation periods (IOPs) explored various mountainous weather and cold-fog conditions. Field observations, NWP forecasts, and large-eddy simulations provided unprecedented data sources to help understand the mechanisms associated with cold-fog weather and to identify and mitigate numerical model deficiencies in simulating winter weather over mountainous terrain. This article summarizes the CFACT field campaign, its observations, and challenges during the field campaign, including real-time fog prediction issues and future analysis.
Validity analysis of digital module based on generic science skills on environmental pollution topic for 10th grade students

The development of digital modules based on interesting generic science skills can be integrated in biology learning. Generic science skills (GSS) are related to skills through application and biological context. The factual and procedural knowledge obtained by students can be explored in the environmental pollution material because of various concepts and solve various real problems. This research is a descriptive study that explains the stages of digital module validation analysis based on generic science skills on environmental pollution for grade 10 high school students. Digital module validation test refers to five aspects such as (1) suitability of material, (2) presentation, (3) language, (4) generic science skills, and (5) visual/appearance. The subjects in the research at the initial review stage were three validators consisting of practitioners who are experts in learning biology and learning media. Based on the results of the study, it is known that the module developed as a whole is very valid in reference to aspects, namely the feasibility of the content aspect, the feasibility of the presentation aspect, the feasibility of the language aspect, the feasibility of the GSS aspect and the appearance, this shows that the digital module produced can be continued at the next stage.