Miracle-dz/UniFAR-FTUs huggingface dataset:
Simple and Swift Acute Ischemic Stroke Therapy based on Cases and Evidence: Possibilities of Cost Reduction and Improving Global Access

There have been significant improvement in the care of acute ischemic stroke (AIS) resulting in reducing death and improving outcomes. Numerous groundbreaking positive randomized controlled trials have demonstrated that strokes with large vessel occlusion (LVO) treated with endovascular mechanical thrombectomy (EVMT) with standard treatment are associated with much better outcomes compared to those treated only with standard therapy. Additional evidence also revealed that the positive outcomes continue to persists for stroke patients with large vessels occlusion if they are treated with 24 hours of symptoms including those with wake-up stroke. The evidence suggests that for every two-patient treated with EVMT, one patient can be saved, which is the highest evidence in the medicine surpassing acute myocardial infarction and other acute lifesaving therapies. Based on these evidence, the local, National and International organizations have updated the guidelines in the treatment of AIS which have remarkably strengthen the process, pathways and standards for acute ischemic stroke management in the developed countries. However, not much progresses have made in the developing and third-world countries for stroke therapies, because of cost, affordability and there are no third-party payers. Most recent trials have further discovered that stroke patient with LVO and a large core volume treated with endovascular perfusion therapy in conjunction with standard treatment do significantly better comparted to standard treatment alone. New trials have also demonstrated that stroke patients undergoing EVMT with or without thrombolytic have equal functional outcome. Additional evidence suggests that non-disabling stroke patients treated with dual antiplatelet have equal functional outcome with less bleeding risk compared to intravenous thrombolysis. These evolving evidences have provided us with the opportunities to simplify the algorithm and treatment of acute ischemic stroke, which not only will cutdown time by eliminating unnecessary steps and redundant therapies, but also will reduce the healthcare cost and improving global access, specially, countries where patients bear the costs. In this review, author presents real life stroke patients treated based on recent evidence and provides with a simple and swift algorithm, that will reduce time to perfusion therapy and will make treatment affordable globally.
Defect Solder Classification in Print Circuit Boards using Machine Learning

This research proposes the solder inspection using the digital image processing technique and machine learning base with our machine vision prototype. There are five classes of classifying solder, including acceptable, short circuit, insufficient, blow hole and too much of solder. Automatic Optical Inspection (AOI) is used for the light source in the designed prototype and industrial camera which are installed on the mini-CNC. For the algorithm, this research applies the scanning line of binary image for detecting short circuit defection and the Random Forrest model for classifying other defects. According to the experiments, the system can classify the defect types for two classes (acceptable and unacceptable types) and five classes as 89% and 71% of accuracy, respectively.
Landscape of Genetic Mutations in Appendiceal Cancers

Simple Summary An analysis of the presence of mutations of 105 genes in appendiceal cancers through the lens of the reviewed literature supports the view that in most of them, the inactivation of tumor suppressor genes, such as TP53 and SMAD4, is required in parallel with the reactivation of genes with oncogenic potentials, such as KRAS, GNAS, and BRAF, which support the main tumor processes, cell proliferation, angiogenesis, and evasion of apoptosis. Of all appendiceal cancers, the most mutated genes are reported in mucinous neoplasms of the appendix, not including those in the RAS–RAF–MEK–ERK signaling pathway, followed by low-grade appendiceal mucinous neoplasms, appendiceal goblet cell adenocarcinomas, and mucinous adenocarcinomas of the appendix, in which this signaling pathway is most frequently affected, showing its importance in their tumorigenesis. Microsatellite instability rarely occurs in appendix cancers, being reported only in adenocarcinomas. Abstract In appendiceal cancers, the most frequently mutated genes are (i) KRAS, which, when reactivated, restores signal transduction via the RAS–RAF–MEK–ERK signaling pathway and stimulates cell proliferation in the early stages of tumor transformation, and then angiogenesis; (ii) TP53, whose inactivation leads to the inhibition of programmed cell death; (iii) GNAS, which, when reactivated, links the cAMP pathway to the RAS–RAF–MEK–ERK signaling pathway, stimulating cell proliferation and angiogenesis; (iv) SMAD4, exhibiting typical tumor-suppressive activity, blocking the transmission of oncogenic TGFB signals via the SMAD2/SMAD3 heterodimer; and (v) BRAF, which is part of the RAS–RAF–MEK–ERK signaling pathway. Diverse mutations are reported in other genes, which are part of secondary or less critical signaling pathways for tumor progression, but which amplify the phenotypic diversity of appendiceal cancers. In this review, we will present the main genetic mutations involved in appendix tumors and their roles in cell proliferation and survival, and in tumor invasiveness, angiogenesis, and acquired resistance to anti-growth signals.
FAKTOR-FAKTOR PERILAKU YANG MEMPENGARUHI PENERIMAAN SISTEM E-LEARNING ESFINDO (E-SCHOOL FOR INDONESIA): STUDI KASUS DI SMA NEGERI 54 JAKARTA TIMUR

Perkembangan teknologi komputer dan teknologi informasi membawa sudut pandang baru tentangbagaimana suatu proses pengajaran dan pembelajaran harus dilaksanakan untuk memperoleh pendidikanberkualitas. Perkembangan teknologi pendidikan ini akan berlanjut dan membantu menciptakan sebuahbudaya pendidikan baru. Esfindo (E-school for Indonesia) adalah portal gratis sistem e-learning untuksekolah menengah yang dibuat oleh Heru Suhartanto dan Tim Fakultas Ilmu Komputer (Fasilkom) UI.Esfindo memiliki cara penyediaan sistem e-learning yang dapat diakses oleh segala lapisan masyarakatIndonesia. Tujuan dibentuk sistem e-learning Esfindo turut membantu mewujudkan sistem pendidikanberkualitas. Namun, apakah sebenarnya sistem e-learning Esfindo tersebut telah diterima dan dimanfaatkansecara maksimal oleh enduser? Model yang digunakan untuk mengetahui faktor-faktor yang mempengaruhipenerimaan Esfindo ini adalah model TAM (Technology Acceptance Model). Secara rinci model TAMmenjelaskan penerimaan TI dengan dimensi-dimensi tertentu yang dapat mempengaruhi penerimaanteknologi oleh pengguna. Jumlah sampel dalam penelitian ini adalah sebesar 150 siswa SMA Negeri 54Jakarta Timur. Untuk mengetahui hubungan diantara variabel penerimaan e-learning Esfindo digunakananalisis SEM (Structural Equation Modelling) dengan bantuan software LISREL versi 8.70. Secaradeskriptif siswa belum sepenuhnya merasakan kegunaan e-learning Esfindo. Masih ada diantara merekayang menganggap bahwa penggunaan e-learning Esfindo adalah sulit. Berdasarkan analisis SEM,kemampuan diri berinternet tidak signifikan mempengaruhi persepsi kemudahan, kemanfataan, dankenikmatan menggunakan e-learning Esfindo; kemudahan menggunakan e-learning Esfindo signifikanmempengaruhi kemanfaatan, keinginan, dan kenikmatan menggunakan e-learning Esfindo; sedangkankeinginan dan kenikmatan menggunakan e-learning Esfindo signifikan mempengaruhi perilakupenggunaan e-learning Esfindo. Faktor yang paling penting dalam penerimaan sistem e-learning Esfindoadalah persepsi kemudahan menggunakan sistem e-learning Esfindo
Evaluación de un extracto herbal en la dieta sobre el comportamiento productivo de cerdos estresados por calor

La exposición de cerdos a estrés por calor (EC), en comparación con termo neutralidad (TN) afecta la integridad del epitelio intestinal, en parte debido a la sobreproducción de radicales libres. Extractos de hierbas (EH) como Capsicum spp. , Pipper nigrum y Zingiber officinales poseen actividad antioxidante. Se evaluó el efecto de adicionar un extracto EH a la dieta en el desempeño productivo de 42 cerdos (27±3 kg) en EC. Los tratamientos fueron: TN-T, cerdos en TN alimentados con dieta testigo; EC-T y EC-EH, cerdos en EC alimentados con dieta testigo sin o con 0.2 % de EH. El experimento consistió de dos periodos; en periodo 1, todos los cerdos tuvieron 8 días de adaptación a la dieta testigo en TN, seguido del periodo experimental de 7 días. La ganancia de peso y consumo de alimento fueron mayores (P <0.05), y la conversión alimenticia tendió a ser mejor (P<0.10) en cerdos EC-EH que en cerdos EC-T. En conclusión, la adición del EH puede contribuir a mejorar algunos parámetros productivos cuando los cerdos están expuestos a EC.
A review of seagrass detection, mapping and monitoring applications using acoustic systems

ABSTRACT Seagrass meadows are key elements of marine ecosystems as they affect the physical, chemical and biological environment and provide habitats for fish and invertebrates. Human activities have caused a deterioration in seagrass which has led to unstable benthic habitats; therefore, to prevent major decline, seagrass distribution must be mapped and monitored. Acoustic systems allow researchers, scientists and decision makers to collect high-resolution datasets such as bathymetry, backscatter and sub-bottom profiles. These systems are able to characterise the properties of the seafloor including plants, sediments and habitats. In this review, we examine seagrass mapping, monitoring and detection applications using acoustic systems in the literature. Although there are various methodologies for data collection, processing, classification and validation, these are limited to certain seagrass species or study areas. Further worldwide research is required to achieve consistent seagrass detection systems with data acquisition, pre-processing, classification and post-processing.
The Convex and Concave Decomposition of Manifolds With Real Projective Structures

— We try to understand the geometric properties of n-manifolds (n ^ 2) with geometric structures modeled on (IiP,PGL(n + 1,R)), i.e., yi-manifolds with projectively flat torsion free affine connections. We define the notion of i-convexity of such manifolds due to Carriere for integers z, 1 < z ^ n — 1, which are generalization of convexity. Given a real projective n-manifold M, we show that the failure of an (n l)-convexity of M implies an existence of a certain geometric object, n-crescent, in the completion M of the universal cover M of M. We show that this further implies the existence of a particular type of affine submanifold in M and give a natural decomposition of M into simpler real projective manifolds, some of which are (n l)-convex and others are affine, more specifically concave affine. We feel that it is useful to have such decomposition particularly in dimension three. Our result will later aid us to study the geometric and topological properties of radiant affine 3-manifolds leading to their classification. We get a consequence for affine Lie groups. Resume (Decomposition convexe et concave des varietes projectives reelles) Notre but est de decrire les proprietes projectives reelles geometriques des varietes munies de (RP", PGL(n + 1, Restructures, ou n >_ 2, c'est-a-dire des varietes equipees de connexions affines projectivement plates et sans torsion. Nous introduisons la definition de la z-convexite, 1 < i < n 1, due a Carriere et generalisant la convexite usuelle. Nous montrons que, si une variete n'est pas (n — l)-convexe, alors un certain objetj^eometrique, appele z-croissant, existe dans Ie complete M du revetement universel M de M. De plus, cette derniere propriete enframe Pexistence d'une sous-variete affine d'un certain type dans M et d'une decomposition de M en varietes projectives plus simples, dont certaines sont (n l)-convexes et d'autres affines, plus precisement concaves affines. Une telle decomposition devrait s'averer utile tout particulierement en dimension 3. En particulier, nous Putiliserons pour classifier les varietes affines radiales de dimension 3. Ici nous en deduisons enfin une consequence pour les groupes de Lie affines. © Memoires de la Societe Mathematique de Prance 78, SMF 1999
A Review on Alzheimer’s Disease Through Analysis of MRI Images Using Deep Learning Techniques

The anatomical structure of the brain has been studied with the help of magnetic resonance imaging (MRI), which has been used to analyze numerous neurological diseases and define pathological areas. Early detection of Alzheimer’s Disease (AD) patients is critical in order to implement preventative measures. Alzheimer’s disease (AD) is the most common chronic disease in the elderly, with a high incidence rate. In recent years, deep learning has seen a lot of success in the medical image analysis. Brain diseases can be more accurately categorized using segmented MRI scans due to in-depth analyses of tissue architecture. Many, complex segmentation approaches have been presented for AD diagnosis. Since deep learning algorithms can yield effective results over a large data collection, they have received interest for use in segmenting the brain’s structure and classifying AD. Consequently, the deep learning techniques are currently favored over machine learning techniques. We discuss how convolutional neural network concepts can be used to study brain anatomy in order to detect AD. New techniques, their results on open datasets, and the benefits of brain MRI segmentation for Alzheimer’s disease categorization are discussed. In this article, the literature on Alzheimer’s disease is briefly reviewed, and the possibility of Deep Learning to improve early diagnosis is discussed.
Effects of olanzapine on anhedonia in schizophrenia: mediated by complement factor H

Background Anhedonia is a trans-diagnostic symptom in schizophrenia and MDD. Our recent work indicated that increased plasma level of complement factor H (CFH) is associated with anhedonia in major depressive disorder. This study hypothesized that CFH is likely to be a biomarker of anhedonia in schizophrenia. Methods A 12-week prospective study is performed to observe the effects of olanzapine on anhedonia and CFH. We used the Chinese version of Snaith-Hamilton Pleasure Scale (SHAPS) to evaluate anhedonic phenotype in patients with schizophrenia. Plasma levels of C-reactive protein (CRP), C3, C4 and CFH were measured. Results Of the recruited 152 samples, patients with anhedonia were found in 99/152 (65.13%). Patients with anhedonia had notably higher PANSS negative subscores, SHAPS total score and higher level of plasma CFH than those without anhedonia (Ps<0.05). Stepwise multivariate linear regression analysis showed that increasing level of plasma CFH was a risk factor for SHAPS total score (β = 0.18, p = 0.03). Of the 99 patients with anhedonia, 74 completed the 12-week follow-up. We observed significantly reduced scores of PANSS, SHAPS and decreased plasma CFH level, when the patients completed this study. The change of SHAPS total score is positively correlated with the level of CFH decrease (p = 0.02). Conclusion Our results implied that plasma CFH levels may be a biomarker for anhedonia in schizophrenia, and the effect of olanzapine on treating anhedonia is through decreasing plasma CFH levels.
Adjective-noun order in Papiamento-Dutch code-switching

In Papiamento-Dutch bilingual speech, the nominal construction is a potential ‘conflict site’ if there is an adjective from one language and a noun from the other. Adjective position is pre-nominal in Dutch (cf. rode wijn ‘red wine’) but post-nominal in Papiamento (cf. biña kòrá ‘wine red’). We test predictions concerning the mechanisms underpinning word order in noun-adjective switches derived from three accounts: (i) the adjective determines word order (Cantone & MacSwan, 2009), (ii) the matrix language determines word order (Myers-Scotton, 1993, 2002), and (iii) either order is possible (Di Sciullo, 2014). An analysis of spontaneous Papiamento-Dutch code-switching production (Parafita Couto & Gullberg, 2017) could not distinguish between these predictions. We used event-related brain potentials (ERPs) to measure online comprehension of code-switched utterances. We discuss how our results inform the three theoretical accounts and we relate them to syntactic coactivation and the production-comprehension link.
Segmental Rectum Resection for Deep Endometriosis and Excision Similarly Improve Sexual Function and Pain

Segmental rectum resections for indications other than endometriosis were reported to result in up to 40% sexual dysfunctions. We, therefore, evaluated sexual function after low bowel resection (n = 33) for deep endometriosis in comparison with conservative excision (n = 23). Sexual function was evaluated with the FSFI-19 (Female Sexuality Functioning Index) and EHP 30 (Endometriosis Health Profile). The pain was evaluated with visual analogue scales. Linear excision and bowel resections improved FSFI, EHP 30, and postoperative pain comparably. By univariate analysis, a decreased sexual function was strongly associated with pain both before (p < 0.0001) and after surgery (p = 0.0012), age (p = 0.05), and duration of surgery (p = 0.023). By multivariate analysis (proc logistic), the FSFI after surgery was predicted only by FSFI before or EHP after surgery. No differences were found between low bowel segmental resection and a more conservative excision. In conclusion, improving pain after surgery can explain the improvement in sexual function. A deleterious effect of a bowel resection on sexual function was not observed for endometriosis. Sexual function in women with endometriosis can be evaluated using a simplified questionnaire such as FSFI-6.
Quality Analysis of Welds Made with an Automatic Battery Pack Spot Welding Machine

This paper presents quality testing of battery pack welds for different welding time parameters of an automatic resistance spot welding machine. Several quality testing methods commonly used in studies of welded joints were described. Finally, the breakage test destructive method was chosen and used in this research. To investigate the influence of welder parameters on the quality of the welded joints, the programmable resistance spot welding machine was designed and constructed. As the studied samples, the 18650 cell type and the 8 mm × 0,15 mm cell packaging nickel plated steel tape were chosen as the most commonly used for the construction of battery packs for personal electric vehicles. The impact of each time constants set on the spot welding process was measured by the self-designed and constructed strength testing machine. After a series of tests with different parameters of spot welding process, the final conclusions were formulated.
Digital consumer perspectives on data access in an emerging market

& Mogashoa 2019; Rey-Moreno & Pather 2020). Developed markets, including Europe, the United States of America (USA) and Oceania, have internet penetration rates above 70 % , as most consumers can afford access to data. In South Africa, consumers live on or below the poverty line and have minimal income for their basic needs, such as food and transport (Statistics South Africa 2021). Therefore, for many South Africans, connecting to the internet is perceived as a luxury (Kemp 2022). In a post-pandemic digital economy where business and marketing strategies are geared towards a hybrid approach Background: Various data access types influence online purchasing in South Africa, contributing to a digital divide. Literature on consumers’ perceptions of data access and its influence on online consumer decision-making is scant. Objectives: This study explores South African consumers’ perceptions of data access and its influence on online consumer decision-making. Method: Plowright’s Framework for Integrated Methodology (FraIM) guided the study’s methodological choices. Through purposive sampling, 25 participants who purchased online 6 months before data collection participated in four virtual focus group discussions. Tesch’s eight steps guided the data analysis procedure. Results: Access to data lies on a continuum from limited to sufficient data access, impacted by location, infrastructure, affordability, time spent online, data usage and device, and supporting factors. Limited data access impedes online consumer decision-making, whereas sufficient data access supports online consumer decision-making. With better data access, consumers can spend more time online deliberating risks by searching for information, reading reviews, comparing alternatives, tracking purchases and influencing other consumers to purchase online. Conclusion: A lack of data access impedes, while sufficient data access supports online consumer decision-making. Contribution: This study adds to the limited knowledge of data access and its implications for decision-making in South Africa. Using the FraIM in a marketing-related study provides novel methodological insights for future research.
Văn hóa Trung Hoa phản ánh qua thành ngữ có chứa chữ “火” (HUO) trong tiếng Hán (So sánh với văn hóa Việt Nam thông qua thành ngữ chứa chữ “Hỏa”, “Lửa” trong tiếng Việt)

Thành ngữ là cụm từ hay đoản ngữ cố định được đúc kết, lưu truyền từ đời này sang đời khác. Trong tiếng Hán và tiếng Việt, thành ngữ là bộ phận cấu thành quan trọng, có vai trò chuyển tải nội hàm văn hóa của hai dân tộc. Trong khuôn khổ bài viết này, dưới góc nhìn ngôn ngữ học văn hóa (Cultural linguistics), chúng tôi tiến hành bàn luận về văn hóa Trung Hoa được phản ánh qua thành ngữ có chứa chữ “火” (HUO) trong tiếng Hán và so sánh với văn hóa Việt Nam thông qua thành ngữ có chứa chữ “Hỏa”, “Lửa” trong tiếng Việt. Kết quả nghiên cứu cho thấy, “lửa” có mối liên hệ mật thiết với phương thức sản xuất nông nghiệp nguyên thủy, chiến thuật quân sự trong chiến tranh thời cổ đại của Trung Quốc, phản ánh trạng thái cảm xúc, phương thức ứng xử, quan niệm sống, triết học, tôn giáo của cả hai dân tộc. Idioms are fixed expressions or short phrases that are summed up and handed down from generation to generation. In Chinese and Vietnamese language, idioms are an important component that plays a key role in conveying the cultural connotations of both countries. Within the scope of this article, from the perspective of cultural linguistics, we discuss Chinese culture reflected in idioms containing the Chinese character "火" (Huo) and compare it with Vietnamese culture in idioms containing the words "Fire" in Vietnamese. Research findings show that fire had a close relationship with Chinese methods of primary cultivation and military strategies in ancient wars, reflecting people's moods, behavioral manners, conceptions of life, philosophy and religions of both countries.