Miracle-dz/UniFAR-FTUs huggingface dataset:
Preference-Tree-Based Real-Time Recommendation System

In the current era of online information overload, recommendation systems are very useful for helping users locate content that may be of interest to them. A personalized recommendation system presents content based on information such as a user’s browsing history and the videos watched. However, information filtering-based recommendation systems are vulnerable to data sparsity and cold-start problems. Additionally, existing recommendation systems suffer from the large overhead incurred in learning regression models used for preference prediction or in selecting groups of similar users. In this study, we propose a preference-tree-based real-time recommendation system that uses various tree models to predict user preferences with a fast runtime. The proposed system predicts preferences based on two balance constants and one similarity threshold to recommend content with a high accuracy while balancing generalized and personalized preferences. The results of comparative experiments and ablation studies confirm that the proposed system can accurately recommend content to users. Specifically, we confirmed that the accuracy and novelty of the recommended content were, respectively, improved by 12.1% and 27.2% compared to existing systems. Furthermore, we verified that the proposed system satisfies real-time requirements and mitigates both cold-start and overfitting problems.
Implementation of Patient Safety in Hospitals: A Qualitative Study

The implementation of patient safety programs is an important thing to do to minimize medical errors, increase health costs and improve the quality of health services. This study qualitatively analyzes the implementation of the patient safety program performed by referring to the 6 target indicators of patient safety. The approach used is a case study design involving 10 informants to be interviewed and observation and document tracing. The results showed that in the implementation of the patient safety program, there were several obstacles, namely ineffective communication due to the instruction provider not reconfirming the instructions given to the implementing nurse. The officers also forgot the position of the drugs to be wary of, and some officers were still found to be negligent in washing their hands. In terms of preventing the risk of falls, collaboration and communication between staff and the patient's family has not been effective. The most basic thing to be immediately addressed is the adequacy of human resources so that a lower workload can optimize the performance of officers in implementing a patient safety culture. Additionally, increasing understanding can be done by providing continuous education and training to health workers.
Child well‐being in early childhood education and care during COVID‐19: Child sensitivity in small, fixed groups

Abstract The article explores child well‐being in Danish early childhood education and care (ECEC) during the time of COVID‐19. A phased reopening of Denmark occurred in spring 2020 under strict health guidelines. Two ECEC institutions were followed first‐hand to observe the impact of the pandemic on pedagogy and child well‐being. Observations and interviews were conducted with follow‐up interviews and an online survey a year later. The findings suggest that the pandemic caused pedagogues to work in a more child‐sensitive way with elevated staff/child ratios and children in small, fixed groups; however, child well‐being was not negatively affected, despite the acute situation
ADDITION OF Ni AND Mo AS AN EFFORT TO INCREASE ETHANOL IN PALM OIL WASTEWATER TREATMENT

: Ethanol is an alternative energy that can be considered to replace energy sources derived from fossils. Ethanol can be produced at the acidogenesis stage of the anaerobic conversion process of palm oil mill effluent wastewater. The efficiency of bioethanol formation is influenced by several factors, including the presence of micronutrients such as molybdenum and nickel. The purpose of this study was to determine the effect of the presence of molybdenum and nickel in the anaerobic wastewater treatment process on the formation of ethanol. Palm oil mill effluent was used as a substrate which was added with Mo with a concentration of 1 and 3 mg/L and Ni of 0.25 and 0.5 mg/L. Mixed culture bacteria as biomass was used in the reactor. CBR reactor is used with an operational time of 72 hours. The reactor performance was investigated by measuring ethanol production, volatile fatty acids, VSS, pH, and soluble COD. It was found that in the reactor with the addition of variations of Mo 3 mg/L and Ni of 0.25 mg/L ethanol production was higher than the other reactor about 578.44 mgCOD/L, while the higher COD removal occurs in the reactor with the addition of Mo and Ni variations of 1 mg/L and 0.25 mg/L respectively, which was 23.4%. These results show that the anaerobic product formation was influenced by the presence of molybdenum and nickel.
Alzheimer’s Disease and Toxins Produced by Marine Dinoflagellates: An Issue to Explore

This paper examined the toxins naturally produced by marine dinoflagellates and their effects on increases in β-amyloid plaques along with tau protein hyperphosphorylation, both major drivers of Alzheimer’s disease (AD). This approach is in line with the demand for certain natural compounds, namely those produced by marine invertebrates that have the potential to be used in the treatment of AD. Current advances in AD treatment are discussed as well as the main factors that potentially affect the puzzling global AD pattern. This study focused on yessotoxins (YTXs), gymnodimine (GYM), spirolides (SPXs), and gambierol, all toxins that have been shown to reduce β-amyloid plaques and tau hyperphosphorylation, thus preventing the neuronal or synaptic dysfunction that ultimately causes the cell death associated with AD (or other neurodegenerative diseases). Another group of toxins described, okadaic acid (OA) and its derivatives, inhibit protein phosphatase activity, which facilitates the presence of phosphorylated tau proteins. A few studies have used OA to trigger AD in zebrafish, providing an opportunity to test in vivo the effectiveness of new drugs in treating or attenuating AD. Constraints on the production of marine toxins for use in these tests have been considered. Different lines of research are anticipated regarding the action of the two groups of toxins.
THE DOG FEMORAL OSTEOBLAST NUMBER POST TRANSPLANTATION OF DEMINERALIZED PORCINE CORTICAL BONE XENOGRAFT

The xenograft function in fracture healing is as osteoinduction. Osteoinduction is stimulated by factors present in the graft material including proteins and growth factors. Proteins and growth factors contained in the graft material are related to the process of osteoblast formation. This study aims to determine the amount of osteoblasts in bone fractures post-transplantation demineralized porcine cortical bone xenograft. Eight males dog aged 3-4 months were used in this study, which was divided into 2 groups at random. Group I is 2 dogs is used as a control, the dog on the diaphysis of the femur bone is drilled with a diameter of 1 cm without graft material. Group II is 6 dog on diaphisis femur bone drilled with a diameter of 1 cm and given Demineralized Porcine Cortical Bone Xenograft. Femoral bone was biopsied at 4th and 8th weeks postoperative for histologically processed and stained with hematoxylin-Eosin. The results showed that the number of osteoblasts in the group given demineralized porcine cortical bone xenograft was higher than the control group. There was no statistically significant difference in the number of osteoblasts between groups (P> 0.05). In conclusion, demineralized porcine cortical bone xenograft can increase the number of osteoblast cells in the bone healing process but the increase is not significant.
Radioembolization Followed by Transarterial Chemoembolization in Hepatocellular Carcinoma

Background and objective: In recent years, combination therapies for hepatocellular carcinoma (HCC) have been increasingly used with superior treatment responses compared to monotherapies. However, the safety and efficacy of the transarterial chemoembolization (TACE) and transarterial radioembolization (TARE) combinations for HCC patients have not been investigated in the literature. In this study, our aim was to evaluate the safety and outcomes of TACE after TARE in HCC patients. Materials and methods: All TARE procedures performed on HCC patients at a single institution between January 2008 and November 2016 were retrospectively reviewed. Seventy-three patients who did not receive any additional transarterial therapy in the areas targeted by TARE were assigned to the “TARE group,” while 27 patients who received TACE after TARE to the same target area were assigned to the “Combo group. ” Post-procedural liver toxicity, tumor response, overall survival (OS), and time to progression (TTP) were evaluated. Results: Fewer patients in the Combo group had worsening liver function than the TARE group based on the change in bilirubin levels (19% vs. 40%; p=0.029) and Child-Pugh score increase (28% vs. 51%; p=0.056). The median OS time of all patients was 11.04 months. The Combo group had a significantly longer median OS of 36.8 months (vs. 10.6, p=0.003) and median TTP of 14.4 months (vs. 5.5, p=0.018). After accounting for selection bias, OS and TTP were still in favor of the Combo group, with hazard ratios of 0.651 (p<0.05) and 0.63 (p<0.05), respectively. Conclusion: The addition of TACE to TARE is a safe and effective treatment in unresectable HCC patients and can be considered in select patients with a lack of complete response or disease progression.
Transcatheter Device Therapy and the Integration of Advanced Imaging in Congenital Heart Disease

Transcatheter device intervention is now offered as first line therapy for many congenital heart defects (CHD) which were traditionally treated with cardiac surgery. While off-label use of devices is common and appropriate, a growing number of devices are now specifically designed and approved for use in CHD. Advanced imaging is now an integral part of interventional procedures including pre-procedure planning, intra-procedural guidance, and post-procedure monitoring. There is robust societal and industrial support for research and development of CHD-specific devices, and the regulatory framework at the national and international level is patient friendly. It is against this backdrop that we review transcatheter implantable devices for CHD, the role and integration of advanced imaging, and explore the current regulatory framework for device approval.
Time-Dependent Odorant Sensitivity Modulation in Insects

Simple Summary Insects, including blood-feeding female mosquitoes, can transmit deadly diseases, such as malaria, encephalitis, dengue, and yellow fever. Insects use olfaction to locate food sources, mates, and hosts. The nature of odorant plumes poses a challenge for insects in locating odorant sources in the environment. In order to modulate the system for the detection of fresh stimuli or changes in odorant concentrations, the olfaction system desensitizes to different concentrations and durations of stimuli. Without this ability, the chemotaxis behaviors of insects are defective. Thus, understanding how insects adjust their olfactory response dynamics to parse the chemical language of the external environment is not only a basic biology question but also has far-reaching implications for repellents and pest control. Abstract Insects use olfaction to detect ecologically relevant chemicals in their environment. To maintain useful responses over a variety of stimuli, olfactory receptor neurons are desensitized to prolonged or high concentrations of stimuli. Depending on the timescale, the desensitization is classified as short-term, which typically spans a few seconds; or long-term, which spans from minutes to hours. Compared with the well-studied mechanisms of desensitization in vertebrate olfactory neurons, the mechanisms underlying invertebrate olfactory sensitivity regulation remain poorly understood. Recently, using a large-scale functional screen, a conserved critical receptor phosphorylation site has been identified in the model insect Drosophila melanogaster, providing new insight into the molecular basis of desensitization in insects. Here, we summarize the progress in this area and provide perspectives on future directions to determine the molecular mechanisms that orchestrate the desensitization in insect olfaction.
Chromatin Structure and Dynamics: Focus on Neuronal Differentiation and Pathological Implication

Chromatin structure is an essential regulator of gene expression. Its state of compaction contributes to the regulation of genetic programs, in particular during differentiation. Epigenetic processes, which include post-translational modifications of histones, DNA methylation and implication of non-coding RNA, are powerful regulators of gene expression. Neurogenesis and neuronal differentiation are spatio-temporally regulated events that allow the formation of the central nervous system components. Here, we review the chromatin structure and post-translational histone modifications associated with neuronal differentiation. Studying the impact of histone modifications on neuronal differentiation improves our understanding of the pathophysiological mechanisms of chromatinopathies and opens up new therapeutic avenues. In addition, we will discuss techniques for the analysis of histone modifications on a genome-wide scale and the pathologies associated with the dysregulation of the epigenetic machinery.
Photocatalytic Degradation of Orange G Dye by Using Bismuth Molybdate: Photocatalysis Optimization and Modeling via Definitive Screening Designs

In the current study, Bismuth molybdate was synthesized using simple co-precipitation procedure, and their characterization was carried out by various methods such as FT-IR, SEM, and P-XRD. Furthermore, the photocatalytic degradation of Orange G (ORG) dye using synthesized catalyst under visible light irradiation was studied. Response surface Method was used for the optimization of process variables and degradation kinetics evaluated by modeling of experimental data. Based on the experimental design outcomes, the first-order model was proven as a practical correlation between selected factors and response. Further ANOVA analysis has revealed that only two out of six factors have a significant effect on ORG degradation, however ORG concentration and irradiation time indicated the significant effects sequentially. Maximum ORG degradation of approximately 96% was achieved by keeping process parameters in range, such as 1 g L−1 loading of catalyst, 50 mg L−1 concentration of ORG, 1.4 mol L−1 concentration of H2O2 at pH 7 and a temperature of 30 °C. Kinetics of ORG degradation followed the pseudo first order, and almost complete degradation was achieved within 8 h. The effectiveness of the Bi2MoO6/H2O2 photo-Fenton system in degradation reactions is due to the higher number of photo-generated e- available on the catalyst surface as a result of their ability to inhibit recombination of e- and h+ pair.
Evolution of Microstructure and Properties of Air-Cooled Friction-Stir-Processed 7075 Aluminum Alloy

A rolled plate of 7075 aluminum alloy was friction-stir-processed (FSP) with simultaneous cooling by an air stream cooled to −11 °C with a jet cooling nozzle. Two variants of air blowing were used: at an angle of 45° to the sample surface and at an angle of 90°. The reference material was a sample subjected to analogous treatment but naturally cooled in still air. The microstructural tests revealed strong grain refinement in all the samples, with higher grain refinement obtained in the air-cooled friction-stir-processed samples. For the naturally cooled samples, the average grain size in the near-surface area was 7.6 µm, while for the air-cooled sample, it was 1.4 µm for the 45° airflow variant and 3.2 µm for the 90° airflow variant. A consequence of the greater grain refinement was that the hardness of the air-cooled friction-stir-processed samples was higher than that of the naturally cooled samples. The improvement in abrasive wear resistance was achieved only in the case of the friction-stir-processed specimens with air cooling. It was found that the change in the air blowing angle affects not only the degree of grain refinement in the stirring zone, but also the geometrical structure of the surface. In all the samples, FSP caused redistribution of the intermetallic precipitates combined with their partial dissolution in the matrix.
The Financial Behaviors of Chasing Athletic Prestige: Evidence from the NCAA Cost of Attendance Policy

Abstract:The NCAA's 2015 Cost of Attendance (COA) policy allowed Division I schools to increase spending on student-athletes. Using data documenting COA implementation and a difference-in-differences design, we explore the relationships between COA and institutions' financial behaviors. Athletics expenditures grew substantially after COA adoption, particularly in the "Power 5" schools. While the Power 5 generated substantial revenue from corporate and other sources, Non-Power 5 institutions relied on institutional and government support to fund their prestige pursuits. The findings suggest COA may have exacerbated longstanding inequities in athletics resources and expenditures and illustrate the financial behaviors of prestige maximization in intercollegiate athletics.
Current status of the early childhood developmental intervention ecosystem in Singapore

Childhood developmental-behavioural issues and disabilities have been identified as the major challenges in child health and to the national healthcare system in Singapore. Dealing with these morbidities requires new and innovative approaches that go far beyond hospital-based care into the community, with structured integration of medical services with education, and social and community support, including a strong collaborative partnership with parents and caregivers. A unique child development programme has evolved in Singapore over the last 30 years. Its main objectives are early identification and treatment of children with developmental and behavioural problems so as to correct developmental dysfunctions, minimise the impact of a child’s disability or prevailing risk factors, strengthen families and establish the foundations for subsequent development. This paper aimed to provide an update of the current ecosystem, along with a review of the fast-changing landscape in recent years.
Edukasi ASI Eksklusif Melalui WhatsApp Group dan Pendampingan pada Tujuh Hari Pertama Kelahiran

The first days of birth are a vulnerable period for babies to be given prelactal food by mothers or families. Exclusive breastfeeding was associated with various factors, including media exposure. Social media such as WhatsApp is a new communication method for Health Education. Mothers exposed to media such as WhatsApp Groups have a greater opportunity to give exclusive breastfeeding. This community service aimed to increase the knowledge of pregnant women about exclusive breastfeeding and increased breastfeeding rates in Palangka Raya City. We used WhatsApp Groups as a medium for providing information about exclusive breastfeeding. Participants in the activity were carried out pretest before and posttest, after the activity was carried out and mentoring was carried out for seven days after birth. There was an increase in knowledge of the activity participants after providing information through WhatsApp Groups, and 70% of participants successfully gave their babies just mother’s milk for seven days after delivery. Health workers can use WhatsApp for providing health information, especially during the covid-19 pandemic.
A Hybrid Deep Learning Approach for ECG-Based Arrhythmia Classification

Arrhythmias are defined as irregularities in the heartbeat rhythm, which may infrequently occur in a human’s life. These arrhythmias may cause potentially fatal complications, which may lead to an immediate risk of life. Thus, the detection and classification of arrhythmias is a pertinent issue for cardiac diagnosis. (1) Background: To capture these sporadic events, an electrocardiogram (ECG), a register containing the heart’s electrical function, is considered the gold standard. However, since ECG carries a vast amount of information, it becomes very complex and challenging to extract the relevant information from visual analysis. As a result, designing an efficient (automated) system to analyse the enormous quantity of data possessed by ECG is critical. (2) Method: This paper proposes a hybrid deep learning-based approach to automate the detection and classification process. This paper makes two-fold contributions. First, 1D ECG signals are translated into 2D Scalogram images to automate the noise filtering and feature extraction. Then, based on experimental evidence, by combining two learning models, namely 2D convolutional neural network (CNN) and the Long Short-Term Memory (LSTM) network, a hybrid model called 2D-CNN-LSTM is proposed. (3) Result: To evaluate the efficacy of the proposed 2D-CNN-LSTM approach, we conducted a rigorous experimental study using the widely adopted MIT–BIH arrhythmia database. The obtained results show that the proposed approach provides ≈98.7%, 99%, and 99% accuracy for Cardiac Arrhythmias (ARR), Congestive Heart Failure (CHF), and Normal Sinus Rhythm (NSR), respectively. Moreover, it provides an average sensitivity of the proposed model of 98.33% and a specificity value of 98.35%, for all three arrhythmias. (4) Conclusions: For the classification of arrhythmias, a robust approach has been introduced where 2D scalogram images of ECG signals are trained over the CNN-LSTM model. The results obtained are better as compared to the other existing techniques and will greatly reduce the amount of intervention required by doctors. For future work, the proposed method can be applied over some live ECG signals and Bi-LSTM can be applied instead of LSTM.
Novel Fractal Electromagnetic Bandgap Structures to Suppress Simultaneous Switching Noise in High Speed Circuits

A fractal low-period coplanar electromagnetic bandgap power/ground planes to suppress simultaneous switching noise is presented in this study. The efiective suppressing band- width of the fractal low-period coplanar electromagnetic bandgap and meander-bridge structure is from 264MHz to 20GHz. The results show the presented structure is superior to other structure for suppressing simultaneous switching noise.
Role of Different Material Amendments in Shaping the Content of Heavy Metals in Maize (Zea mays L.) on Soil Polluted with Petrol

Petroleum substances are among the xenobiotics that most often contaminate the natural environment. They have a strong effect on soil, water, and other components of the environment. The aim of this pot experiment has been to determine the effect of different soil material amendments (compost, 3%; bentonite, 2% relative to the soil mass or calcium oxide, in amounts corresponding to one full hydrolytic acidity) on the content of heavy metals in aerial parts of maize (Zea mays L.) grown on soil polluted with petrol (0, 2.5, 5, and 10 cm3 kg−1 of soil). The content of all heavy metals, except copper, in the aerial biomass of maize was positively correlated, but biomass yield negatively correlated, with the increasing doses of petrol. The highest increase in the content of heavy metals was noted for chromium and manganese. Materials used for phytostabilisation (compost, bentonite, and calcium oxide) had a significant effect on the content of heavy metals and biomass yield of maize. They contributed to the modified accumulation of elements, especially chromium, copper, and cobalt in the aerial biomass of maize. In comparison with the control series (without material amendments), the application of calcium oxide proved to be most effective. It had the most evident influence on the chemical composition of maize, limiting the accumulation of lead, zinc, manganese, and iron and increasing biomass yield.