Miracle-dz/UniFAR-FTUs huggingface dataset:
Tapered plastic optical fiber loop coated with ZnO nanorods using multiple channels for relative humidity sensing

To utilize the evanescent wave on a plastic optical fiber (POF), a humidity sensor was fabricated based on a tapered POF with a loop shape and coated with zinc oxide (ZnO) nanorods. The POF was tapered manually to a diameter of 0.90 mm by using the polishing method. ZnO nanorods were synthesized using the hydrothermal method. The obtained results revealed that the increase in the length of the tapered POF loop coated with ZnO nanorod had provided an excellent sensing performance as an RH sensor in terms of sensitivity and repeatability properties. Streszczenie. Aby
Cerium Oxide (CeO2) Nanoparticles Could Have Protective Effect Against COVID-19

The COVID-19 pandemic has been incredibly influential on public health, life, and economy for one year, and this type of virus could be our life in the future. Currently, there are some vaccines or combination therapies of anti-viral drugs. However, the mutation rates of the virus could be unpredictable, and the known treatments could be ineffective in fighting the virus's diseases. Nanotechnology included metal nanoparticles, has been used due to their antivirus, antibacterial or antioxidant properties. CeO2 (Cerium oxide) metal nanoparticles have great potential against viruses or bacteria. Also, CeO2 metal nanoparticles have antioxidant properties and immunomodulatory effects. Thus, this paper suggests the PEGylated CeO2 metal nanoparticles as a new approach for treating COVID-19.
Soluble IL-2R Levels at Baseline Predict the Development of Severe Respiratory Failure and Mortality in COVID-19 Patients

Risk stratification of coronavirus disease-19 (COVID-19) patients by simple markers is critical to guide treatment. We studied the predictive value of soluble interleukin-2 receptor (sIL-2R) for the early identification of patients at risk of developing severe clinical outcomes. sIL-2R levels were measured in 197 patients (60.9% males; median age 61 years; moderate disease, n = 65; severe, n = 132, intubated and/or died, n = 42). All patients received combined immunotherapies (anakinra ± corticosteroids ± intravenous immunoglobulin ± tocilizumab) according to our local treatment algorithm. The endpoint was the composite event of intubation due to severe respiratory failure (SRF) or mortality. Median (interquartile range) sIL-2R levels were significantly higher in patients with severe disease, compared with those with moderate disease (6 (6.2) vs. 5.2 (3.4) ng/mL, p = 0.017). sIL-2R was the strongest laboratory predictive factor for intubation/death (hazard ratio 1.749, 95%CI 1.041–2.939, p = 0.035) after adjustment for other known risk factors. Youden’s index revealed optimal sIL-2R cut-off for predicting intubation/death at 9 ng/mL (sensitivity: 67%; specificity: 86%; positive and negative predictive value: 57% and 91%, respectively). Delta sIL-2R between the day of event or discharge minus admission date was higher in patients that intubated/died than in those who did not experience an event (2.91 (10.42) vs. 0.44 (2.88) ng/mL; p = 0.08)). sIL-2R on admission and its dynamic changes during follow-up may reflect disease severity and predict the development of SRF and mortality.
Sapiteede atreesia tõttu teostatud elusdoonori maksa transplantatsioon lapsel. Ülevaade ja haigusjuhu kirjeldus

Sapiteede atreesia korral osutub sageli vajalikuks maksatransplantatsioon. Kuna imikute ja vaikelaste suremus kadaveerse doonorelundi ootelehel olles on suur, on uha enam kasutust leidnud elusdoonori maksa siirdamine. Siirdamise jarel ohustab last nii doonorelundi aratouge kui ka ravist tulenevad infektsioonidega seonduvad probleemid. Artiklis on kirjeldatud lapse haigusjuhtu, kellele esimese lapsena Eestist siirati elusdoonori maks. Patsient viibis parast sundi lastehaiglas ebaselge pohjusega ikteruse tottu. 2,5kuuselt teostati operatsioon, sest kahtlustati sapiteede atreesiat. Diagnoos leidis kinnitust, kuid esmasest kirurgilisest ravist pusivat efekti ei saadud. Elupaastvaks ravivoimaluseks oli maksasiirdamine, mis teostati Stockholmis Hudding haiglas. Doonoriks oli lapse ema. Siirdamise jarel on lapse maksafunktsioon olnud hea, pusinud on posttransplantatiivse lumfoproliferatsiooni oht. Probleemiks on seni jaanud ebaselge pohjusega malabsorptsioonisundroom. Eesti Arst 2009; 88(Lisa4):77−80
Pengaruh Corporate Governance, Firm Age, Dan Ownership Structure Terhadap Earning Management

The purpose of this study was to determine the effect of corporate governance, firm age, and ownership structure on earnings management. The population used is a company engaged in manufacturing which is listed on the Indonesia Stock Exchange (IDX) website, with a research period from 2016-2018. This research uses purposive sampling method with predetermined criteria. Earning management is calculated using the discretionary accruals method. The results of this study stated that corporate governance with an independent commissioners proxy had no significant negative effect on earnings management, firm age had a significant positive effect on earnings management, and ownership structure with a proxy for public ownership had a significant negative effect on earnings management.
E-tutors’ instructional strategies in teaching the design process in virtual classroom: A case in an Open Distance eLearning (ODeL) environment

The technology curriculum is positioned to have the same status as those in mathematics and science curricula. This existence is supplied as a means of advancing knowledge and contributing to key insights into the subject's design process curriculum, particularly in the context of an ODeL. Innovative instructional methodologies are better positioned to develop design process knowledge within the needs of the ODeL environment to meet this requirement. "How did the e-tutors' gained pedagogical knowledge effect the students' learning of the design process? " was studied as a question to help the inquiry get more important insights. This work used a quantitative way to answer the main research question by allowing students to describe how they believe their e-tutor abilities to select instructional tactics to teach the design process. The quantitative data was employed as a scope and depth of comprehension and confirmation of the data gathered in the quantitative approach. Three hundred fifty postgraduate students were chosen from a year module of a degree as a sample. The instructional tactics of the e-tutors in teaching the design process in the virtual classroom were evaluated through an online survey. In the results of the study, in virtual classroom settings, e-tutors were found to have less ability to innovate and employ a broad educational style. It can be recommended to use an alternative model of e-tutor appointments instead of using the existing.
Collapse Dynamics of Vortex Beams in a Kerr Medium with Refractive Index Modulation and PT-Symmetric Lattices

Using the two-dimensional nonlinear Schrödinger equation, the collapse dynamics of vortex beams in a Kerr medium with refractive index modulation and parity–time (PT) symmetric lattices are explored. The critical power for the collapse of vortex beams in a Kerr medium with real optical lattices (i.e., refractive index modulation lattices) was obtained and discussed. Numerical calculations showed that the number of self-focusing points, the locations of the collapse, and the propagation distances for collapse are sensitively dependent on the modulation factors, topological charge numbers, and initial powers. When the vortex optical field propagates in a Kerr medium with real optical lattices, the optical field will collapse into a symmetrical shape. However, the shape of the vortex beam will be chaotically distorted and collapse in asymmetric patterns during propagation in a Kerr medium with PT-symmetric lattices because of the presence of the complex refraction index. Introducing PT-symmetric lattices into nonlinear Kerr materials may offer a new approach to controlling the collapse of vortex beams.
Pemanfaatan Web Services Instagram Sebagai Media Kompetisi Publikasi Pada Website XLAwards2014

Kompetisi yang diselenggarakan secara online mulai sering dilakukan, salah satu penyelenggara adalah provider XL dengan kompetisinya yang bernama XL Awards. Tahun 2014 ini XL Awards menambahkan kategori baru yaitu Publikasi yang memungkinkan peserta mengikuti kompetisi fotografi menggunakan kamera smartphone. Instagram dipilih sebagai platform utama dan nantinya hasil karya akan ditampilkan pada website XL Awards.Website XL Awards dibangun dengan platform WordPress yang memungkinkan penambahan fitur menggunakan plugins. Alpine PhotoTile for Instagram dipilih sebagai plugin yang menjembatani antara Instagram dan WordPress kemudian juga untuk menampilkan foto dari Instagram dengan tagar #XLAwards2014 yang ditampilkan pada halaman WordPress.
Situation Assessment/Diagnosis Model Based on Bayesian Networks for Hydropower Equipment

Aiming at uncertainty and the poor generality of hydropower equipment fault diagnosis, a general situation assessment model based on Bayesian Networks is put forward. The model includes three levels, i. e. , character level, understanding level, and assessment level. Nodes in Bayesian networks are divided into situation and event nodes according to their functions. During reasoning the information acquired by sensors are taken as the evidence of event node to update the probability of situation node and in turn, to influence the probability of event nodes. The diagnosis model in application of hydropower speed governor system shows that the veracity can be up to 95.2 % , thus indicating the reliability provided by the situation assessment model.
Exogenous Salicylic Acid Modifies Cell Wall Lignification, Total Phenolic Content, PAL-Activity in Wheat (Triticum aestivum L.) and Buckwheat (Fagopyrum esculentum Moench) Plants under Cadmium Chloride Impact

Salicylic acid (SA) is considered one of the most important plant signaling molecules involved in abiotic and biotic stress tolerance. Application of 0,05 mM SA enhanced plants’ tolerance to cadmium stress by modulating levels of several metabolites, including components of antioxidative defense, osmolytes, secondary metabolites, and metal-chelating compounds. Seeds of bread wheat (Triticum aestivum L.) and buckwheat (Fagopyrum esculentum Moench) were presoaked in 0,05 mM SA/or distilled water for 5 h, with the following germination in a dark thermostat for 3 d. Uniform seedlings were planted into +Cd / or -Cd-containing substrate and grown for 16/8 h light/dark. It was revealed that seed pretreatment with SA alone caused a 3-5-fold decrease in phenylalanine ammonia-lyase (PAL) activity and total phenolic content compared to the control water treatment. Seed pretreatment with SA alleviated the negative impact of Cd on plant growth, PAL activity, and total phenolic content. These results indicate that salicylate treatment alleviates Cd toxicity by modifying lignin synthesis and accumulation of flavonoids in wheat and buckwheat plants. Protective effects were more pronounced for buckwheat with the studied variables' high total phenolic content.
Directional and Adaptive Oil Self‐Transport on a Multi‐Bioinspired Grooved Conical Spine

Manipulating oil droplets in an aqueous solution offers great opportunities to develop advanced devices in the fields of water remediation, chemical micro‐reactor, etc. Although conical structures can achieve a directional oil droplet motion, the continuous and adaptive fluid self‐transport in complicated environments is still a challenge. Inspired by the distinctive oil transport capability of fishbone and the anisotropic grooved structure of rice leaves, this work presents a multi‐bioinspired grooved conical spine (BGCS) for improved oil manipulation. Benefiting from the cooperative effect of the asymmetric Laplace pressure and the surface capillary force, the BGCS possesses the reliable functions of ultrafast and continuous oil transport under water, in air, and even across the air–water interface. Compared with the original cone, the BGCS demonstrates a nine times faster transporting velocity and a five times larger capacity. It is envisioned that this updated oil‐collecting cone with its cooperative structure should find real‐world applications.
Morphologic-Molecular Transformation of Oncogene Addicted Non-Small Cell Lung Cancer

Patients with non-small cell lung cancer, especially adenocarcinomas, harbour at least one oncogenic driver mutation that can potentially be a target for therapy. Treatments of these oncogene-addicted tumours, such as the use of tyrosine kinase inhibitors (TKIs) of mutated epidermal growth factor receptor, have dramatically improved the outcome of patients. However, some patients may acquire resistance to treatment early on after starting a targeted therapy. Transformations to other histotypes—small cell lung carcinoma, large cell neuroendocrine carcinoma, squamous cell carcinoma, and sarcomatoid carcinoma—have been increasingly recognised as important mechanisms of resistance and are increasingly becoming a topic of interest for all specialists involved in the diagnosis, management, and care of these patients. This article, after examining the most used TKI agents and their main biological activities, discusses histological and molecular transformations with an up-to-date review of all previous cases published in the field. Liquid biopsy and future research directions are also briefly discussed to offer the reader a complete and up-to-date overview of the topic.
Quantitative Analysis of Core Lipid Production in Methanothermobacter marburgensis at Different Scales

Archaeal lipids have a high biotechnological potential, caused by their high resistance to oxidative stress, extreme pH values and temperatures, as well as their ability to withstand phospholipases. Further, methanogens, a specific group of archaea, are already well-established in the field of biotechnology because of their ability to use carbon dioxide and molecular hydrogen or organic substrates. In this study, we show the potential of the model organism Methanothermobacter marburgensis to act both as a carbon dioxide based biological methane producer and as a potential supplier of archaeal lipids. Different cultivation settings were tested to gain an insight into the optimal conditions to produce specific core lipids. The study shows that up-scaling at a constant particle number (n/n = const.) seems to be a promising approach. Further optimizations regarding the length and number of the incubation periods and the ratio of the interaction area to the total liquid volume are necessary for scaling these settings for industrial purposes.
Web 2.0 and Knowledge Sharing. A Literature Review

Web 2.0 has changed the way people interact with each other, search, share, and create knowledge. Technology infrastructure gives organizations a diverse set of ICT options to create and share knowledge. Changes in technology are exponential, and particularly the impact of Web 2.0 in knowledge sharing and contribution can lead to many areas of study. The use of technology is beneficial at all levels in the organization, and are impacting how people interact with each other in different organizational contexts, such as educational, organizational, and political. The expectation in the initial phase of this research would be that knowledge sharing and collaboration may be affected.
Epigenetic Determinants of Racial Disparity in Breast Cancer: Looking beyond Genetic Alterations

Simple Summary A substantial disparity in breast cancer incidence and mortality exists between African American (AA) and European American (EA) women. However, the basis for these disparities is poorly understood. In this article, we describe that gene–environment interactions mediated through epigenetic modifications may play a significant role in racial disparities in BC incidence and outcomes. Our in silico analyses and an in-depth literature survey suggest that there exists a significant difference in epigenetic patterns between AA and EA women with breast cancer. Herein, we describe the environmental factors that contribute to these epigenetic changes, which may underlie the disparate racial burden in patients with breast cancer. We suggest that AA women with higher basal epigenetic changes, may have higher pre-disposition to cancer onset, and an aggressive disease course. Pre-existing racial differences in epigenetic profiles of breast tissues raises the possibility of examining these profiles for early diagnosis. Abstract Breast cancer (BC) is the most commonly diagnosed cancer in women. Despite advancements in BC screening, prevention, and treatment, BC incidence and mortality remain high among African American (AA) women. Compared with European American (EA) women, AA women tend to be diagnosed with more advanced and aggressive tumors and exhibit worse survival outcomes. Most studies investigating the determinants of racial disparities in BC have focused on genetic factors associated with African ancestry. However, various environmental and social stressors over an individual’s life course can also shape racial stratification in BC. These social and environmental exposures result in long-term changes in gene expression mediated by epigenetic mechanisms. Epigenetics is often portrayed as an intersection of socially patterned stress and genetic expression. The enduring nature of epigenetic changes makes them suitable for studying the effects of different environmental exposures over an individual’s life course on gene expression. The role of differential social and environmental exposures in racial disparities in BC suggests varied epigenetic profiles or signatures associated with specific BC subtypes in AA and EA women. These epigenetic profiles in EA and AA women could be used as biomarkers for early BC diagnosis and disease prognosis and may prove valuable for the development of targeted therapies for BC. This review article discusses the current state of knowledge regarding epigenetic differences between AA and EA women with BC. We also discuss the role of socio-environmental factors, including psychosocial stress, environmental toxicants, and dietary factors, in delineating the different epigenetic profiles in AA and EA patients with BC.
The Impact of Urban Education on the Income Gap of Urban Residents: Evidence from Central China

It is very important for a country's sustainable economic and social development to reduce the income gap between urban residents. Through investigating the impact of urban education level and its different levels on the income gap of urban residents in Central China, this paper provides the basis for formulating scientific and rational urban education development policies in Central China. Based on Central China's urban dynamic panel data, this paper examines the impact by using the system GMM (Generalized Method of Moments). The results show that overall, the improvement of urban education level helps to narrow the income gap of urban residents in Central China cities. Specifically, improvement of primary education level and secondary education level helps to narrow the income gap of urban residents, and improvement of higher education level enlarges the income gap of urban residents. Nonetheless, with further development of higher education in the cities, the income structure of lower-middle-income and low-income groups will be optimized, and subsequently higher education in cities will probably narrow the income gap between urban residents. In terms of the type of cities, improvement of education level in provincial capitals widens the income gap of urban residents, and improvement of education level in prefecture-level cities and county-level cities helps to narrow the income gap of urban residents. For all three types of cities, improvement of primary education level helps to narrow the income gap of urban residents, and the improvement of higher education level widens the income gap of urban residents. The improvement of secondary education level widens the income gap of urban residents in provincial capital cities but reduces the income gap of residents in prefecture-level cities and county-level cities. The policy implication from this study is that, to effectively and expeditiously narrow the income gap of urban residents in Central China, prefecture-level and county-level cities need to vigorously develop urban education, especially urban primary education and secondary education．At the same time, cities in Central China also need to actively develop higher education. Although the income gap of urban residents might be widened temporarily in the short term, the development of urban higher education will increase property income and net operating income of the local middle-low-income and low-income groups in the long term. Ultimately this policy would optimize the income structure of local urban residents and narrow the income gap of urban residents.
Antioxidant and Antiglycation Effects of Cistus × incanus Water Infusion, Its Phenolic Components, and Respective Metabolites

Reactive oxygen and carbonyl species promote oxidative and carbonyl stress, and the development of diabetes, metabolic syndrome, cardiovascular diseases, and others. The traditional herb Cistus × incanus is known for its antioxidant properties; therefore, the current study aimed to assess how the chemical composition of a C. incanus water infusion corresponds with its antioxidative and antiglycative effects in vitro. The composition of infusions prepared from commercial products was analyzed with UHPLC-ESI-qTOF-MS. Total phenolics, flavonoids, and non-flavonoid polyphenols were determined. Antioxidant activity of infusions and selected polyphenols was investigated using DPPH, ABTS, and FRAP. Fluorometric measurements and methylglyoxal capture were performed to investigate the antiglycation activity. PCA and PLS-DA models were applied to explore the correlation between chemical and antioxidant results. The principal flavonoids in C. incanus were flavonols. In vitro tests revealed that a stronger antioxidant effect was demonstrated by plant material from Turkey rich in flavonoids, followed by Albania and Greece. Flavonols and ellagic acid displayed stronger antiradical and reducing power than EA-derived urolithins. Hyperoside was the most potent inhibitor of glycation. The results indicate that flavonoids are primarily responsible for rock rose antioxidant and antiglycation properties. PLS-DA modeling can be used to identify the origin of plant material with sensitivity and specificity exceeding 86%.
Septic Shock Secondary to Severe Gastroenteritis Resulting From Sapovirus Infection

Sapovirus causes acute gastroenteritis (AGE) which manifests as severe diarrhea and vomiting. It is most often seen in, but not limited to, children and toddlers but can occur in people of all ages. It is typically more prevalent in low to middle-income countries but has also been reported in progressive countries such as the United States. Due to the universal use of reverse transcriptase-polymerase chain reaction (RT-PCR) testing, the reported incidence of sapovirus has continued to grow as the culprit agent in both AGE outbreaks and isolated cases. Its symptoms resemble what is seen with rotavirus but with a milder clinical course. This discussion explores the dire implications of a relatively understated pathogen. Here, we present a rare case of a 20-year-old woman who presented with septic shock secondary to severe gastroenteritis as a result of sapovirus infection.