Miracle-dz/UniFAR-FTUs huggingface dataset:
Regulatory Networks: Inferring functional relationships through Co-expression

E -ma il: k enth . br dz@ p u gG en e ex p ressio n d a ta n o t o n ly p rov id e u s in sig h ts in to d iscrete tra n scrip t a b u n -d a n ce o f sp eciÞ c g en es, b u t co n ta in cry p tic in fo rm a tio n th a t ca n n o t rea d ilyb e a ssessed w ith o u t in terp reta tio n . W e a g a in u sed d a ta o f th e p la n t A ra bid o p -sis th a lia n a a s o u r referen ce o rg a n ism , y et th e a n a ly sis p resen ted h erein ca nb e p erfo rm ed w ith a n y o rg a n ism w ith va rio u s d a ta so u rces. W ith in th e cell,in fo rm a tio n is tra n sd u ced v ia d i! eren t sig n a lin g ca sca d es a n d resu lts in d if-feren tia l g en e ex p ressio n resp o n ses. T h e in co m in g sig n a ls a re p erceiv ed fro mu p strea m sig n a lin g co m p o n en ts a n d h a n d ed to d ow n strea m m essen g ers th a tfu rth er d eliv er th e sig n a ls to e! ecto r p ro tein s w h ich ca n d irectly in s u en ce g en eex p ressio n . In m o st ca ses, w e ca n a ssu m e th a t p ro tein s, w h ich a re co n n ected too th er sig n a lin g co m p o n en ts w ith in su ch a reg u la to ry n etw o rk , ex h ib it sim ila rex p ressio n tra jecto ries. T h u s, w e ex tra cted a k n ow n fu n ctio n a l n etw o rk fro mlitera tu re a n d d em o n stra ted th a t it is p o ssib le to su p erim p o se m icro a rray ex -p ressio n d a ta o n to th e p a th w ay s. T h ereb y, w e co u ld fo llow th e in fo rm a tio n s owth ro u g h tim e res ected b y g en e ex p ressio n ch a n g es. T h is a llow ed u s to p red ict,w h eth er th e u p strea m sig n a l w a s tra n sm itted fro m k n ow n elem en ts co n ta in edin th e n etw o rk o r relay ed fro m o u tsid e co m p o n en ts. W e n ex t co n d u cted th ev ice v ersa a p p ro a ch a n d u sed la rg e sca le m icro a rray ex p ressio n d a ta to b u ild aco -ex p ressio n m a trix fo r a ll g en es p resen t o n th e a rray. F ro m th is, w e co m p u teda reg u la to ry n etw o rk , w h ich a llow ed u s to d ed u ce k n ow n a n d n ov el sig n a lin gp a th w ay s.K ey w o rd s: L a rg e sca le g en e ex p ressio n d a ta , co -ex p ressio n m a trix a n a ly sis,g en e reg u la to ry n etw o rk s, sig n a l tra n sd u ctio n p a th w ay, A tG en E x p ress
Current distribution on the elements of a square loop frequency selective surface

A modal analysis gave the current distribution on the capacitive and inductive components of the square for plane wave incidence up to 50° in the principal planes. 12 current functions were required to reproduce the observed transmission through the surface. Their complex amplitudes are tabulated to show the significance of symmetrical and asymmetrical functions at two reflection resonant frequencies.
The economic impact of quality management systems in Portuguese certified companies: Empirical evidence

Purpose – Despite all the studies carried out in order to analyze the impact of quality management systems implementation and certification over companies' financial performance, conclusions reached so far have been of a contradictory nature. Some authors conclude that there is a positive relationship between ISO 9001 certification and companies' financial improvement, while others do not find evidence to support such a relationship. Overall, no consistent evidence could therefore be found in the literature concerning the ISO 9001 impact over companies' business financial performance. This work aims to provide a contribution in this area.Design/methodology/approach – Using a public database of Portuguese companies' financial information, this paper describes the results obtained from studying the economic impact of quality management systems, based on a statistical analysis.Findings – The results suggest that companies with higher financial performance do present a greater propensity to implement and cert.
Finite Element Simulation for Laser Ablation of Carbon Fiber Epoxy Composite

In order to predict the size and shape of the laser ablative hole, a 3D finite element model was developed to simulate the Nd:YAG laser ablation of carbon fiber epoxy composite. For given irradiation conditions, good agreement with experimental data relating to hole dimensions. The numerical results and experimental observations indicate that with the irradiation time increasing, the domain under investigation temperature raises rapidly and the further to the spot center, the smaller the temperature raises. After 0.093s the target surface temperature is higher than the critical temperature of composite, so the removal of the material on first composite layer occurs. It also can be observed that heat energy of the laser spread within the material and the isotherm ribbon, as well as crater border, is step-like.
Trajectory generation and control for quadrotors

This thesis presents contributions to the state-of-the-art in quadrotor control, payload transportation with single and multiple quadrotors, and trajectory generation for single and multiple quadrotors. In Ch. 2 we describe a controller capable of handling large roll and pitch angles that enables a quadrotor to follow trajectories requiring large accelerations and also recover from extreme initial conditions. In Ch. 3 we describe a method that allows teams of quadrotors to work together to carry payloads that they could not carry individually. In Ch. 4 we discuss an online parameter estimation method for quadrotors transporting payloads which enables a quadrotor to use its dynamics in order to learn about the payload it is carrying and also adapt its control law in order to improve tracking performance. In Ch. 5 we present a trajectory generation method that enables quadrotors to fly through narrow gaps at various orientations and perch on inclined surfaces. Chapter 6 discusses a method for generating dynamically optimal trajectories through a series of predefined waypoints and safe corridors and Ch. 7 extends that method to enable heterogeneous quadrotor teams to quickly rearrange formations and avoid a small number of obstacles. Degree Type Dissertation Degree Name Doctor of Philosophy (PhD) Graduate Group Mechanical Engineering & Applied Mechanics First Advisor Vijay Kumar
TriNet “ShakeMaps”: Rapid Generation of Peak Ground Motion and Intensity Maps for Earthquakes in Southern California

Rapid (3-5 minutes) generation of maps of instrumental ground-motion and shaking intensity is accomplished through advances in real-time seismographic data acquisition combined with newly developed relationships between recorded ground-motion parameters and expected shaking intensity values. Estimation of shaking over the entire regional extent of southern California is obtained by the spatial interpolation of the measured ground motions with geologically based frequency and amplitude-dependent site corrections. Production of the maps is automatic, triggered by any significant earthquake in southern California. Maps are now made available within several minutes of the earthquake for public and scientific consumption via the World Wide Web; they will be made available with dedicated communications for emergency response agencies and critical users.
A systematic approach for precision electrostatic mode tuning of a MEMS gyroscope

In this paper a systematic approach to precision electrostatic frequency tuning of the operational modes of a MEMS ring vibratory gyroscope is presented. In both rate and rate integrating gyroscopes the frequency split between the two modes of vibration which detect the Coriolis acceleration is one of the principal factors in determining the sensitivity and noise floor of the sensor. In high precision applications in the defence/aerospace sector a frequency split of the order of 10 mHz or less is highly desirable. In the ground-breaking Hemispherical Resonator Gyroscope (HRG) electrostatic tuning has been employed as a tuning mechanism. However, a description of the procedure is not available in the literature. The tuning scheme described here involves assessing mode mistuning by the ratio of the in-phase and quadrature components of the response to an external force that has similar properties to the gyroscopic force resulting from Coriolis action, and choosing the tuning voltages so that independent modification of the elements of the system stiffness matrix can be achieved. Experiments on a commercially available gyroscope with a natural frequency of 14 kHz show that the frequency split can be reduced from 1.5 Hz to 6 mHz. This represents a frequency precision of better than 1 part in a million.
RE-ENGINEERING STRATEGY AND PERFORMANCE OF LARGE MANUFACTURING FIRMS IN KENYA

Purpose: Most of the large manufacturing firms in Kenya have been experiencing declining performance in terms of revenue, sales and the profit margins for more than a decade. This has seen some of the large manufacturing firms in the country consider strategies such as relocating or restructuring their operations, opting to serve the local market through importing from low-cost manufacturing areas instead of adopting turnaround strategies. This therefore prompted a question on whether turnaround strategies such as reengineering strategy are effective for the manufacturing firms; hence the motivation of this study. Methodology: This study was informed by theory of constraints. A descriptive research design was adopted while 708 large manufacturing firms in Kenya registered under the Kenya Association of Manufacturers were targeted. The sample size for the study was 249 firms selected randomly from all the 14 sectors of the manufacturing industry in Kenya. The data collection instrument was a questionnaire, while mean, frequencies and percentages were used to describe the data. Correlation and regression analysis were done to show direction, magnitude and significance of the association between the variables. Findings: The findings revealed that re-engineering strategy had significant and positive influence on the performance of large manufacturing firms in Kenya. The findings further revealed that organizational culture had significant moderating effect on the relationship between reengineering strategy and performance of large manufacturing companies. The study concluded that reengineering strategy as one of the turnaround strategies positively influenced the performance of large manufacturing companies. Unique Contribution to Theory, Practice and Policy: It is therefore recommended that the management of large manufacturing firms uphold reengineering strategy in order to enhance performance.
Rolling Process of AZ31 Alloy Bar Using Three Roller Mill

Structure and pass system of Y-type mill which have three-roller is analyzed. A hot rolling method to produce magnesium alloy bars through flat triangle-arc triangle-round pass system is put forward. Using Deform-3D software, the rolling process of AZ31 alloy bar is simulated to determine the parameters of the rolling process and die. The experiment verifies that the hot rolling process is feasible. The organizational structure is analyzed with metallographic microscope, and the results show that dynamic recrystallization is occurred, the grain size is obviously refined, and the mechanical property of the material is improved in hot rolling process.
Experimental analysis of buckling in aircraft skin panels by fibre optic sensors

Three blade-stiffened CFRP panels with co-cured stiffener webs, manufactured by means of an elastomeric mould, have been tested under compressive load. Several Bragg grating sensors have been surface bonded on two of the stiffened panels and have been embedded into the stiffener webs of the third panel. The Bragg grating sensors measured the strain distribution in the stiffener web and in the skin panels. The bucking onset was clearly detected in every case, the post-buckling behaviour can be tracked, but the information is heavily dependent on the right choice of the sensor position and the buckling mode. To calibrate the system, and to evaluate the influence of different curing pressures, and the use of unidirectional or fabric prepreg material, tensile test specimens were made on flat panels. The strain measurements provided by the optical fibre sensors in tensile tests were compared with the strain measurements provided by conventional clamp extensometers.
Characteristics and Prevalence of Early Chronic Obstructive Pulmonary Disease in a Middle-Aged Population: Results from a Nationwide-Representative Sample

Introduction Few studies have examined the prevalence and associated factors of early chronic obstructive pulmonary disease (COPD) in Asians. Objective To evaluate the prevalence of early COPD and its associated factors among non-institutionalized middle-aged Korean adults. Methods A total of 3195 participants aged 40–49 years from the 2016–2018 Korea National Health and Nutrition Examination Survey were included in this study. Patients (1) aged less than 50 years, (2) with a minimum of 10 pack-years of smoking, and (3) with forced expiratory volume in 1 s/forced vital capacity (FEV1/FVC) below the lower limit of normal were diagnosed with early COPD. The prevalence and odds ratio (OR) for early COPD were measured using multivariate logistic regression analysis, and the demographic data, anthropometric measurements, socioeconomic status, and lifestyle factors were considered covariates. Results The overall prevalence of early COPD among the middle-aged Korean population was 2.4% (4.4% in men and 0.4% in women), while that in participants with ≥10 pack-years was 8.2% (8.1% in men and 11.3% in women). A multivariate logistic regression model showed that male sex, urban residence, chronic sputum production, and hypertriglyceridemia were associated with increased ORs for early COPD in middle-aged, non-institutionalized Korean adults. Conclusion Early COPD is prevalent among middle-aged smokers in Korea. Efforts are needed to reduce the potential negative effects of early COPD on public health in Korea and other Asian countries.
Wind‐aerated lagoons for sustainable treatment of wastewaters from small communities

Biological treatment processes that utilise wind‐aerated lagoons have proved popular for small communities because of their negligible sludge production. Scottish Water has recently constructed one such system, known as the Aero‐Fac (North Dakota, USA), and this paper reports on an intensive 12‐month study designed to both monitor the lagoon performance and establish the key design parameters. Over the monitoring period the final effluent complied with both Scottish Environmental Protection Agency discharge consents and Scottish Water performance guarantees for biochemical oxygen demand and total suspended solids, which averaged 9 and 28 mg/L, respectively. The lagoons showed an accelerated growth of algae during the summer months, but this did not adversely affect the final effluent suspended solids. The lagoons also achieved a faecal coliform removal of around 3.4 log and an average effluent ammonia of 7.6 mg/L. However, the ammonia removal was seasonal with a better performance in the summer months, which probably reflects take‐up by the growing algal population over this period. No sludge was wasted from the lagoon over the monitoring period yet it accumulated only sparingly in the lagoons, mainly around the inlet of the primary lagoon. The estimated per capita sludge accumulation rate was 0.0047 m3/person/year. The total capital costs of the scheme were £1.65 million, and of this the lagoon cost was £840 000. The capital costs of £420 per capita make this more expensive than other, similar options, but plant operating costs are significantly reduced.
Dual-frequency circularly polarised annular-ring microstrip antenna

The novel design of the circular polarisation (CP) for an annular-ring antenna operated at its TM11 and TM12 modes is presented. The CP radiations of the proposed design are achieved by placing an L-shaped strip connected to two orthogonal sides of the inner boundary of the annular patch. The dual-frequency CP operations are excited by a single probe-feed, and no additional 90° phase shifter and impedance-transformer circuit are required. A prototype of the proposed design was implemented and measured. Measured results show that broadside radiation patterns with good CP characteristics are obtained at the two operating resonant modes. Agreement between measured and numerical results is satisfactory.
PVDF: An automatic Patch-based Vulnerability Description and Fuzzing method

Patch-based vulnerability analysis is a hot topic for security researchers and attackers, some important semantic can be used to discover new bugs or errors via information revealed from patch differences. However, automatic description for patched differences is always viewed as such a difficult task that similar work is usually achieve in manual method. In this paper, we present an automatic patch-based description for a type of privilege elevation vulnerability, and perform fuzzing test to excavate unknown bugs in further step. Focusing on feature in this type of vulnerability, we recognize vulnerability-related positions from patched differences, and divide them into multi-level attributes via normalized definitions. Furthermore, we present analysis procedure as relationship measurement among several attributes: binary difference, data structure of object, operation semantic and constraint formula. The root cause and exploitation method for vulnerability can be described on the leverage of gradual attribute deductions. At last, a CF-oriented fuzzing method is introduced based on verification of semantic and constraint formula. The effectiveness and performance of our prototype have been tested in evaluation, it proves that patch-related bugs all can be described in PVD (Patch-based Vulnerability Description) automatically, and some new bugs can be discovered in PVF (Patch-based Vulnerability Fuzzing). In addition, average time consumption of global running is less than systems or projects of related work.
Microencapsulated healing agents for an elevated-temperature cured epoxy: Influence of viscosity on healing efficiency

Among many applications, elevated-temperature cured epoxy resins are widely used for high-performance applications especially for structural adhesive and as a matrix for structural composites. This is due to their superior chemical and mechanical properties. The thermosetting nature of epoxy produces a highly cross-linked polymer network during the curing process where the resulting material exhibited excellent properties. However, due to this cross-linked molecular structure, epoxies are also known to be brittle, and once a crack initiated in the material, it is difficult to arrest the crack propagation. Earlier research found that the inclusion of encapsulated healing agents is able to introduce self-healing ability to the room-temperature cured epoxies. The current study investigated the self-healing behaviour of an elevated-temperature cured epoxy, which incorporated the dual-capsule system loaded with diglycidyl-ether of bisphenol-A (DGEBA) resin and mercaptan. The microcapsules were prepared by the in-situ polymerisation method while the fracture toughness and the self-healing capability of the tapered-double-cantilever-beam (TDCB) epoxy specimens were measured under Mode-I fracture toughness testing. We investigated the effect of temperature on viscosity of the healing agents and how these values influence the formation of uniform healing on the fracture surfaces. It was found that incorporation of the dual-capsule self-healing system onto an elevated-temperature cured epoxy slightly changed the fracture toughness of the epoxy as indicated by the Mode-I testing. In the case of thermal healing at 70°C, the self-healing epoxy exhibited a recovery of up to 111% of its original fracture toughness, where a uniform spreading of the healant was observed. The excellent healing behaviour is attributed to the lower viscosity of the healant at higher temperature and the higher glass transition temperature (Tg) of the produced healant film. The DSC analysis confirmed that the healing process was not contributed by the post-curing of the host epoxy.
Automated Indirect Optical Micromanipulation of Biological Cells Using Indirect Pushing for Minimizing Photo-Damage

Precise micromanipulation of cells or other living systems is allowing for cell transport, sorting, characterization of mechanical properties, cell-cell interaction, migration studies, etc. In this paper, we report an automated indirect pushing-based approach for micromanipulation of cells using dielectric silica beads. In this approach, an optically actuated dielectric silica bead pushes on other bead that in turn pushes the cell, thereby minimizing photo-damage. We have defined three parametrized atomic maneuvers namely, push, align, and go behind the intermediate bead and used them to compose a feedback plan for in-direct pushing. We have developed a simplified dynamics model, which is used in the simulation of operations involving pushing of cells using optically trapped beads. We also present an optimization-based approach for automated tuning of maneuver parameters for different turning angles and measurement noise to increase the robustness of the developed feedback planner. Finally, we have tested the developed planner on a physical setup and obtained experimental results.Copyright © 2012 by ASME
Field Oriented Control of AFPMSM for Electrical Vehicle Using Adaptive Neuro-Fuzzy Inference System (ANFIS)

• Vector control was used to improve dynamic performance of AFPMSM. • ANFIS was used to integrate the speed and torque constraints. • The approach gave great speed performance. • Results gave reduction 10% in torque ripple. Axial Flux Permanent Magnet Synchronous Motor (AFPMSM) are very attractive candidates for driving applications due to their high efficiency, high torque-toweight ratio, high power density, small magnetic thickness, and simplicity of construction. On the other hand, AFPMSM produces undesirable torque ripple in the developed electromagnetic torque, affecting their output performance. An intelligent control method is proposed in this paper to reduce torque ripple and improve the dynamic performance of AFPMSM. The vector control, employing the Field Oriented Control (FOC) technique, was used to improve the dynamic performance of the AFPMSM. The speed and torque controllers are achieved using the decoupling method. The intelligent control was designed to improve the performance of AFPMSM obtained from PI-PSO. The Adaptive Neuro-Fuzzy Inference System (ANFIS) was used as an Intelligent controller to integrate both the speed and torque constraints in a single training procedure. Training data for ANFIS was obtained from PI-PSO with a multi-objective cost function that includes the torque ripple and speed response criteria . The approach gave great results in terms of speed performance in different operating conditions and in tracking the required speed in load and no-load. In addition, the torque ripple was reduced by 10.04% and 46.67% compared with PI-PSO and Multi-objective cost function of speed, respectively. A R T I C L E I N F O Handling editor: Ivan A. Hashim
DrawLight: Learning Colors by Creating Physically Interactive and Immersive Lighting

In this paper, we present DrawLight, a physically interactive and immersive lighting system aimed at young children, ages two to six, to help them learn colors and immerse themselves into their imaginary colorful environment by creating correspondent ambient lighting through their former paintings and colorful objects combination. As the same time as children are drawing colorful pictures, playing with colorful objects, or hanging painting somewhere inside the space, specially designed ambient lights will change to the correspond color mode. DrawLight invites children to explore the transformation from concrete colorful painting and physical objects into abstract ambient lighting, which gives children an immersive impression about the color effect. General terms: Children, painting, colorful physical objects, color learning, creating interactive and immersive lighting