Miracle-dz/UniFAR-FTUs huggingface dataset:
Big Data: Challenges and Opportunities on the E-evidence

In the era of big data, it seems like seeking for a needle in a haystack to find a tiny evidence associated with proceedings from the mass of electronic data,and the complexity of data is also a challenge to the quality of E-evidence, as not only increases the cost of collecting E-evidence, but also makes the imbalance of E-evidence a difficult structural problems to solve. The era of big data has spawned new methods of collecting E-evidence, and the mining technology of big data also provides new ideas to the discovery of E-evidence. In the era of big data, it is thus necessary for us to make the collection mode of evidence play a bigger role by using big data processing technology. Confronting the effects of big data, we should improve the rights and obligations of collecting E-evidence, give corresponding weight to the collection of E-evidence by using new technologies, which can effectively protect the parties equitably access to evidence, maintain equitable competition, and promote litigation and the discovery of authenticity in the civil proceedings.
AAZTA-Derived Chelators for the Design of Innovative Radiopharmaceuticals with Theranostic Applications

With the development of 68Ga and 177Lu radiochemistry, theranostic approaches in modern nuclear medicine enabling patient-centered personalized medicine applications have been growing in the last decade. In conjunction with the search for new relevant molecular targets, the design of innovative chelating agents to easily form stable complexes with various radiometals for theranostic applications has gained evident momentum. Initially conceived for magnetic resonance imaging applications, the chelating agent AAZTA features a mesocyclic seven-membered diazepane ring, conferring some of the properties of both acyclic and macrocyclic chelating agents. Described in the early 2000s, AAZTA and its derivatives exhibited interesting properties once complexed with metals and radiometals, combining a fast kinetic of formation with a slow kinetic of dissociation. Importantly, the extremely short coordination reaction times allowed by AAZTA derivatives were particularly suitable for short half-life radioelements (i.e., 68Ga). In view of these particular characteristics, the scope of this review is to provide a survey on the design, synthesis, and applications in the nuclear medicine/radiopharmacy field of AAZTA-derived chelators.
Recuperação energética de resíduos de painéis MDF (medium density fiberboard) por meio da torrefação e briquetagem

Os painéis MDF (medium density fiberboard) são os mais produzidos e utilizados no Brasil, sendo esse, o maior responsável pela geração de resíduos nas indústrias de móveis. Tratamentos térmicos aliados a briquetagem podem viabilizar a utilização dos resíduos, visto que se tem um aumento significativo na densidade energética e redução volumétrica. Esse estudo teve como objetivo principal, produzir briquetes a partir de resíduos de painéis MDF revestidos e não revestidos torreficados para geração de energia. Os resíduos de painéis de MDF, com e sem revestimento de adesivo melamínico (BP), foram torrificados em um reator semicontínuo à temperatura de 300 °C por 20, 30 e 40 minutos. Os resíduos foram caracterizados quanto às propriedades físicas e químicas antes e após os tratamentos térmicos. O material foi briquetado e determinada a carga de ruptura, densidade aparente, perfil densitométrico por imagens de raios x, teor de umidade e combustibilidade. Os briquetes de MDF torrificados com tempo de residência de 40 minutos obtiveram melhores propriedades energéticas. Não foram detectadas quantidades significativas de metais pesados. Os briquetes produzidos com resíduos de MDF cru e revestidos torrificados por 40 minutos tiveram umidade de equilíbrio de 6,34%, carga de ruptura de 168 Kgf, densidade aparente de 1,030 g.cm -3 e 4,36 Gcal.m -3 de densidade energética. A densitometria de raios X foi eficaz pra avaliar a variabilidade de densidade aparente dos briquetes em imagens em 2D e 3D. A combustibilidade dos briquetes verificou temperaturas de pico de 583 e 605 ºC para os briquetes de MDF revestidos e não revestidos torrificados por 40 minutos. A partir deste estudo, conclui-se que os briquetes produzidos a partir de resíduos de MDF revestidos torrificados são uma alternativa do ponto de vista tecnológico para o aproveitamento de resíduos de MDF da indústria moveleira para recuperação energética. Palavras-chave: Aproveitamento energético. Densificação de biomassa. Resíduo moveleiro. Energia renovável.
Unraveling Microbial Volatile Elicitors Using a Transparent Methodology for Induction of Systemic Resistance and Regulation of Antioxidant Genes at Expression Levels in Chili against Bacterial Wilt Disease

Microbial volatiles benefit the agricultural ecological system by promoting plant growth and systemic resistance against diseases without harming the environment. To explore the plant growth-promoting efficiency of VOCs produced by Pseudomonas fluorescens PDS1 and Bacillus subtilis KA9 in terms of chili plant growth and its biocontrol efficiency against Ralstonia solanacearum, experiments were conducted both in vitro and in vivo. A closure assembly was designed using a half-inverted plastic bottle to demonstrate plant–microbial interactions via volatile compounds. The most common volatile organic compounds were identified and reported; they promoted plant development and induced systemic resistance (ISR) against wilt pathogen R. solanacearum. The PDS1 and KA9 VOCs significantly increased defensive enzyme activity and overexpressed the antioxidant genes PAL, POD, SOD, WRKYa, PAL1, DEF-1, CAT-2, WRKY40, HSFC1, LOX2, and NPR1 related to plant defense. The overall gene expression was greater in root tissue as compared to leaf tissue in chili plant. Our findings shed light on the relationship among rhizobacteria, pathogen, and host plants, resulting in plant growth promotion, disease suppression, systemic resistance-inducing potential, and antioxidant response with related gene expression in the leaf and root tissue of chili.
Theoretical Study of the Charge Transfer of Five Derivatives of Tetrathiafulvalene Complexed with Unsubstituted Tetracyanoquinodimethane

Our work consisted of a theoretical study of the charge transfer of five Tetrathiafulvalene- Tetracyanoquinodimethane (TTF-TCNQ) complexes. Global reactivity and charge transfer descriptors were determined at theory level B3LYP/6-311G (d,p). These descriptors revealed that the Tetrathiafulvalene (TTF) has a reducing character when the Tetracyanoquinodimethane (TCNQ) has an oxidizing character, the oxidation-reduction reaction between these two molecules is a polar reaction characterized by a high charge transfer, the electronic flow moves from TTF to TCNQ and the conductivity of these charge transfer complexes increases when the HOMOTTF-LUMOTCNQ energy gap decreases. When the dipole moment of TTF molecules increases, the conductivity of the complexes they form with unsubstituted TCNQ increases and leads to high charge transfer. We intend to deepen this study by proposing new complexes with more improved electrical properties.
The Change in the Structure and Functionality of Ferritin during the Production of Pea Seed Milk

Understanding the effect of thermal treatment on the physical and chemical properties of protein and its mechanisms has important theoretical implications in food science. Pea seed ferritin (PSF) is an iron storage protein naturally occurring in pea seeds, which represents a promising iron supplement. However, how thermal processing affects the structure and function of PSF remains unknown. In this work, during the production of pea seed milk, we investigated the effect of thermal treatments at boiling temperature for two different times (5 and 10 min), respectively, on the structure and function of PSF. The results demonstrated that thermal treatment resulted in a pronounced change in the primary, secondary, and tertiary structure, iron content, and iron oxidation activity of PSF. However, the shell-like structure of PSF can be kept during the processing of pea seed milk. Interestingly, upon thermal treatment, both thermal-treated samples exhibit larger higher iron absorption rate by Caco-2 than untreated PSF at the same protein concentration. Such an investigation provides a better understanding of the relationship between the structure and function of food protein, as affected by thermal treatment.
On-line-Erkennung von Mehrfachfehlern in einem experimentellen Batchprozeß / On line detection of multiple faults in an experimental batch process

Die frühzeitige und sichere Erkennung fehlerhafter Zustände und Veränderungen in dynamischen Prozessen gewinnt in der automatisierungstechnischen Praxis wachsende Bedeutung. Viele der bisher dazu veröffentlichten Untersuchungen beschränken sich jedoch auf die Behandlung von Fehlererkennung und -diagnose in Prozessen, die sich als linearisierte zeitinvariante Systeme beschreiben lassen. Nur wenige Arbeiten beschäftigen sich konsequent mit Fehlererkennung in nichtlinearen Systemen, wie sie typischerweise in der Praxis vorkommen. Dieser Beitrag stellt ein neues Verfahren zur Erkennung auch gleichzeitig auftretender Fehler, sog. Mehrfachfehler vor. Dazu wird ein nichtlinearer Zustandsbeobachter zur Residuenberechnung mit einer Methode zur optimalen Klassifikation von Fehlermerkmalen, aufhauend auf dem Konzept des Learning Vector Quantizer (LVQ), kombiniert. Das für den online-Einsatz geeignete Verfahren wurde an einer Experimentieranlage mit gutem Erfolg erprobt. On line detection of multiple faults in an experimental batch process Early and safe detection of abnormal changes in dynamical processes is of great importance in many branches of industry. Most of the investigations, reported to-date, focus on fault detection and diagnosis in linearized time-invariant systems. Only a few papers deal with nonlinear systems, which are very common in most applications. This article presents a new approach for detection of simultaneously occurring faults, i.e. multiple faults. It combines a nonlinear state observer for residual generation with a method for optimal classification of fault features, based on the concept of the Learning Vector Quantizer (LVQ). The approach, designed for online-usage, was tested on an experimental process with satisfactory results.
Research on Performance of Inertial Velocity Aiding GPS/SINS Integration System

GPS/INS integration systems are widely used in different fields. Since GPS receiver carrier loop has lost lock during maneuver,the velocity aiding signal of code loop is derived from the inertial navigation system. Because of the correlation between the pseudorange measurement error and the inertial velocity etror,it will make the integration system operation instable. On the basis of GPS receiver code loop operation characteristics, the code loop tracking error is considered in the Kalman filter.Optimal navigation satellites are selected in real time by a GPS simulator. The navigation performance of a GPS/SINS integration system is analyzed during the airplane maneuver.The simulation results show that the code loop operates in the tracking state,the integration system operates normally and stably,and the navigation accuracy of the system is evidently improved when the correlanon between the pseudo-range measurement error and the inertial velocity error is eliminated.
MAQASID SHARIA AND ISLAMIC BANK PERFORMANCE: A SYSTEMATIC REVIEW

Maqasid sharia contains elements of maintaining faith, guarding oneself, maintaining reason, maintaining bloodlines and safeguarding property. Until now, the maqasid of sharia is considered to be the most ideal as a measure of the performance of sharia banking with the dimension of maqasid sharia with the aim of Islamizing banking. Islamic banking as a business entity that aims to make a profit but must also comply with Islamic law and provide benefits in the social sector through the distribution of zakat, infaq, alms, csr, and qardul hasan loans. This study is a literature review study on the relationship between Islamic maqasid and Islamic banking performance measurement. This study contains the philosophy, terminology of sharia maqasid, and research results relating it to the performance of Islamic banking. The conclusion from the literature review is that Islamic maqasid can be adopted as a measure of the performance of Islamic banking. Many empirical studies have examined the use of maqasid sharia as an indicator, but there is no consistency. Therefore, Islamic banking regulators need to prepare instruments and guidelines so that these measurements can be adopted easily and uniformly.
Roles and Regulation of BCL-xL in Hematological Malignancies

Members of the Bcl-2 family are proteins that play an essential role in the regulation of apoptosis, a crucial process in development and normal physiology in multicellular organisms. The essential mechanism of this family of proteins is given by the role of pro-survival proteins, which inhibit apoptosis by their direct binding with their counterpart, the effector proteins of apoptosis. This family of proteins was named after the typical member Bcl-2, which was named for its discovery and abnormal expression in B-cell lymphomas. Subsequently, the structure of one of its members BCL-xL was described, which allowed one to understand much of the molecular mechanism of this family. Due to its role of BCL-xL in the regulation of cell survival and proliferation, it has been of great interest in its study. Due to this, it is important to research its role regarding the development and progression of human malignancies, especially in hematologic malignancies. Due to its variation in expression in cancer, it has been suggested that BCL-xL can or cannot play a role in cancer depending on the cellular or tissue context. This review discusses recent advances in its transcriptional regulation of BCL-xL, as well as the advances regarding the activities of BCL-xL in hematological malignancies, its possible role as a biomarker, and its possible clinical relevance in these malignancies.
Design, Fabrication, and Testing of the DARPA / Wright Lab "Smart Wing" Wind Tunnel Model

The concept of an adaptive aircraft wing, i.e., whose shape parameters such as camber, span-wise twist, and thickness can be varied to optimize the wing shape for various flight conditions, has been extensively studied by numerous researchers [1-8]. While the aerodynamic benefits (in terms of increased lift/drag ratios, improved maneuverability, and delayed flow separation) have been analytically and experimentally established, the complexity and weight penalty of the designs and actuation mechanisms have limited their practical implementation. Recent developments in sensors and actuators using smart materials could potentially alleviate the shortcomings of prior designs, leading the way to a more practical "smart" adaptive wing which responds to changes in flight and environmental conditions by optimally modifying its shape. This paper presents the results of recent work conducted under a Defense Advanced Research Projects Agency (DARPA) contract entitled "Smart Structures and Materials Development - Smart Wing". In particular, development and testing of the smart wing wind tunnel model are presented. Limitations and potential benefits of adaptive wing designs are also discussed, along with recommendations for future work required to develop an operational smart adaptive wing.
Recognition of Volleyball Player's Arm Motion Trajectory and Muscle Injury Mechanism Analysis Based upon Neural Network Model

At present, in sports training for volleyball, it still mainly depends on the personal experience of the coach. Training costs are high, and the quality is difficult to maintain stable. Even with the introduction of training assistance software, it is often necessary to manually enter complex data, and the research samples are mostly single individuals. Serving is one of the basic and important technical movements of volleyball, and its standardization is of great significance to the stable performance of the scene. This article proposes an analysis of the volleyball player's arm trajectory based on the background of human posture recognition and analysis, based on the neural network model. The changes in the angles of the shoulders, elbows, and wrist when serving the ball reflect the different trajectories of the arm. Experiments show that the height of the throwing arm from the ground accounts for 98% of the height. The horizontal angle of the throwing arm at the moment the ball leaves the hand is positively correlated with the throwing time and height, and the reasonable trajectory has an impact on the stability of the throwing ball. The closer the trajectory of the tossing arm is to the vertical, the more stable the tossing is.
Tobacco growing and tobacco use

Abstract Tobacco use is associated with an annual global economic cost of two trillion dollars and mortality of half of its regular users. Tobacco leaf cultivation is the starting point of the tobacco cycle. Tobacco farming employs millions of small-scale tobacco farmers around the globe, most of whom are out growers who rely on the tobacco industry. This paper aims to map the regions of greatest tobacco production globally (i.e., the US, Brazil, China, Indonesia, India, and Zambia) and tobacco use rates in these locations. Smoking rates were higher in those areas, except for India, where important population subgroups reported an upward trend for tobacco smoking. In general, there was a relationship between tobacco farming and tobacco smoking. Tobacco farming may lead to a higher risk of tobacco use and lower adherence to tobacco control policies. Therefore, promoting viable alternative livelihoods for tobacco farmers must have dual benefits. Additionally, specific health prevention policies might be necessary for those populations reporting higher tobacco use and lower perception of tobacco-related health risks.
The Role of Interleukins in Recurrent Implantation Failure: A Comprehensive Review of the Literature

Recurrent implantation failure (RIF) is a multifactorial condition affecting 10–15% of in vitro fertilization (IVF) couples. Data suggest that functional dysregulation of the endometrial immune system constitutes one of the main pathophysiological mechanisms leading to RIF. The aim of this article is to provide a thorough presentation and evaluation of the role of interleukins (ILs) in the pathogenesis of RIF. A comprehensive literature screening was performed summarizing current evidence. During implantation, several classes of ILs are secreted by epithelial and stromal endometrial cells, including IL-6, IL-10, IL-12, IL-15, IL-18, and the leukemia inhibitory factor. These ILs create a perplexing network that orchestrates both proliferation and maturation of uterine natural killer cells, controls the function of regulatory T and B cells inhibiting the secretion of antifetal antibodies, and supports trophoblast invasion and decidua formation. The existing data indicate associations between ILs and RIF. The extensive analysis performed herein concludes that the dysregulation of the ILs network indeed jeopardizes implantation leading to RIF. This review further proposes a mapping of future research on how to move forward from mere associations to robust molecular data that will allow an accurate profiling of ILs in turn enabling evidence-based consultancy and decision making when addressing RIF patients.
Propagation Mechanism of Cyber Physical Security Risks in Power Systems

In a cyber-physical power system, cyber space risks can result in the failure of a power system. Thus, it is necessary to study the propagation mechanism of cyber physical security risks. In this paper, the basic propagation path of cyber physical security risks in a cyber-physical power system is first analyzed. Then, a risk propagation model of the cyber physical security is proposed based on the cellular automata and the characteristics of a cyber-physical power system. Finally, numerical simulations are carried out based on a 9-bus system in MATPOWER. Through these simulations, some important impact factors on the propagation of cyber physical security risks are discussed, such as the transfer probability and recovery rate. The impacts of the simulation time interval on simulation results are discussed as well.
Simultaneous Spectrophotometric Estimation of Metformin, Saxagliptin and Dapagliflozin in Marketed Formulations

Type 2 diabetes mellitus (T2DM) is characterized by insulin resistance and/or decreased production, resulting in elevated blood sugar levels. It is rapidly spreading around the world and has become a leading cause of mortality in recent years. The basic goal of T2DM treatment is to maintain a healthy blood sugar level. It is a difficult undertaking to develop a single analytical method for estimating individual drugs from a multidrug combination. A novel, simple, precise, accurate, repeatable, and effective UV spectrophotometric approach is developed and validated for the simultaneous quantification of a ternary combination of metformin (MET), saxagliptin (SXG), and dapagliflozin (DAG) (DGF). The FDA recently authorised bulk forms and mixed in tablet dosage forms for use in the treatment of Type 2 diabetes mellitus using the simultaneous equation approach. Methanol: water (80:20 v/v) was used to make the standard and sample solutions. MET, SXG, and DGF had maximum values of 232.0, 212.0, and 272.0nm, respectively. The calibration curves for MET, SXG, and DGF are linear in the concentration ranges of 10-50g/mL, 1-5g/mL, and 5-25g/mL, respectively. According to ICH rules, the results of the simultaneous equation technique analysis were examined and validated for various parameters.
Compensating Strategy Based on Dynamic Matrix Control for Networked Control System

Considering the data packets uncertainty in networked control system(NCS),its influence on NCS and relevant existing controlling methods are analyzed.Then a distributed NCS model is developed where the controller is event-time with senor and actuator both time driven.Based on the simple and practical dynamic matrix method for predictive control,a new compensating strategy is proposed for network time delay and packet dropout and simulated.The results show that the output from the NCS after compensation strategy is much the same as the output from the system where the network time delay remains unchanged but the data packets arrive on time.The effectiveness of the compensating strategy is thus verified.
Prediction of storm surges on the east coast of India

Nomograms to estimate peak storm surges generated by tropical cyclones impinging on, the east coast of India are prepared using Jelesnianski's. SPLASH (1972) model. The. pre-computed nomograms accommodate fixed values for pressure drop, radius of maximum wild, vector motion of storms and offshore bathymetry. Two sets of nomograms are presented -one for the northeast coast of India where the slope of the continental shelf is extremely shallow -the other for the remaining east coast where the slope in general is extremely steep. A nomogram to correct the magnitude of the peak surge for tidal effects is also prepared for the notheast coast of India where the semidiurnal tide range is large. A method to estimate total sea level elevation along a coastal stretch by means of nomograms is given for the northeast coast of India.