Miracle-dz/UniFAR-FTUs huggingface dataset:
Review of radiation effects on ReRAM devices and technology

A review of the ionizing radiation effects on resistive random access memory (ReRAM) technology and devices is presented in this article. The review focuses on vertical devices exhibiting bipolar resistance switching, devices that have already exhibited interesting properties and characteristics for memory applications and, in particular, for non-volatile memory applications. Non-volatile memories are important devices for any type of electronic and embedded system, as they are for space applications. In such applications, specific environmental issues related to the existence of cosmic rays and Van Allen radiation belts around the Earth contribute to specific failure mechanisms related to the energy deposition induced by such ionizing radiation. Such effects are important in non-volatile memory as the current leading technology, i.e. flash-based technology, is sensitive to the total ionizing dose (TID) and single-event effects. New technologies such as ReRAM, if competing with or complementing the existing non-volatile area of memories from the point of view of performance, also have to exhibit great reliability for use in radiation environments such as space. This has driven research on the radiation effects of such ReRAM technology, on both the conductive-bridge RAM as well as the valence-change memories, or OxRAM variants of the technology. Initial characterizations of ReRAM technology showed a high degree of resilience to TID, developing researchers’ interest in characterizing such resilience as well as investigating the cause of such behavior. The state of the art of such research is reviewed in this article.
Multi-Model Data Modeling and Representation: State of the Art and Research Challenges

Following the current trend, most of the well-known database systems, being relational, NoSQL, or NewSQL, denote themselves as multi-model. This industry-driven approach, however, lacks plenty of important features of the traditional DBMSs. The primary problem is a design of an optimal multi-model schema and its sufficiently general and efficient representation. In this paper, we provide an overview and discussion of the promising approaches that could potentially be capable of solving these issues, along with a summary of the remaining open problems.
A Curriculum Integrating STEAM and Maker Education Promotes Pupils' Learning Motivation, Self-Efficacy, and Interdisciplinary Knowledge Acquisition

Contemporary society expects learners to synthesize large amounts of available information and take advantage of interdisciplinary knowledge to tackle complex, real-world issues. STEAM education aims to cultivate students' ability to solve such problems through interdisciplinary thinking but is often represented by courses that are merely disjointed arrays of school subjects. On the other hand, Maker education harnesses society's enthusiasm for technological innovation and creativity but overlooks the scientific principles that underpin these processes. This research presents a novel elementary school course informed by the interdisciplinary principles of STEAM, integrated with Maker's focus on technology and creativity. The course design also utilized engineering design as a meta-thematic framework. A total of 164 third-grade pupils participated in the research, with responses analyzed using descriptive statistical methods. The findings indicated that the integrated design of the course promoted pupils' learning motivation, self-efficacy, and acquisition of interdisciplinary knowledge. These effects were not gender-specific and demonstrate the potential applicability of a STEAM/Maker integrated approach to curriculum design in other settings.
RNA-seq Insights Into the Impact of Alteromonas macleodii on Isochrysis galbana

Phycospheric bacteria may be the key biological factors affecting the growth of algae. However, the studies about interaction between Isochrysis galbana and its phycospheric bacteria are limited. Here, we show that a marine heterotrophic bacterium, Alteromonas macleodii, enhanced the growth of I. galbana, and inhibited non-photochemical quenching (NPQ) and superoxide dismutase (SOD) activities of this microalgae. Further, we explored this phenomenon via examining how the entire transcriptomes of I. galbana changed when it was co-cultured with A. macleodii. Notable increase was observed in transcripts related to photosynthesis, carbon fixation, oxidative phosphorylation, ribosomal proteins, biosynthetic enzymes, and transport processes of I. galbana in the presence of A. macleodii, suggesting the introduction of the bacterium might have introduced increased production and transport of carbon compounds and other types of biomolecules. Besides, the transcriptome changed largely corresponded to reduced stress conditions for I. galbana, as inferred from the depletion of transcripts encoding DNA repair enzymes, superoxide dismutase (SOD) and other stress-response proteins. Taken together, the presence of A. macleodii mainly enhanced photosynthesis and biosynthesis of I. galbana and protected it from stress, especially oxidative stress. Transfer of fixed organic carbon, but perhaps other types of biomolecules, between the autotroph and the heterotroph might happen in I. galbana-A. macleodii co-culture. The present work provides novel insights into the transcriptional consequences of I. galbana of mutualism with its heterotrophic bacterial partner, and mutually beneficial associations existing in I. galbana-A. macleodii might be explored to improve productivity and sustainability of aquaculture algal rearing systems.
Drug Screening Implicates Chondroitin Sulfate as a Potential Longevity Pill

Discovering compounds that promote health during aging (“geroprotectors”) is key to the retardation of age-related pathologies and the prevention of chronic age-related diseases. In in-silico and model organisms’ lifespan screens, chondroitin sulfate has emerged as a geroprotective compound. Chondroitin sulfate is a glycosaminoglycan attached to extracellular matrix proteins and is naturally produced by our body. Oral supplementation of chondroitin sulfate shows a high tolerance in humans, preferable pharmacokinetics, a positive correlation with healthy human longevity, and efficacy in deceleration of age-related diseases in randomized clinical trials. We have recently shown that chondroitin sulfate supplementation increases the lifespan of C. elegans. Thus, chondroitin sulfate holds the potential to become a geroprotective strategy to promote health during human aging. This review discusses the two major potential mechanisms of action, extracellular matrix homeostasis and inhibition of inflammation, that counteract age-related pathologies upon chondroitin sulfate supplementation.
Towards a Sustainable Energy Planning Strategy: The Utilisation of Floor Area Ratio for Residential Community Planning and Design in China

Floor Area Ratio, commonly known as FAR, is a primary planning metric in urbanism. It is commonly known as the ratio of accumulated built floor areas against the size of a site/plot. In recent years, China's rapid urban development has resulted in a substantial increase in FAR, particularly in residential areas. A notable shift from low-rise row housing typology to a more common high-rise residential unit is certainly a key factor behind the increase of energy use in many Chinese cities. This factor highlights the need for a sustainable energy planning strategy at the community level. As a novelty, this study reflects on the FAR changes in the context of China, and evaluates the impacts on energy use at the community scale. This study tests four FAR models of 1.0, 2.5, 3.0, and 4.0 and provides a computational modelling analysis, with a comparison analysis. FAR models of 1.0 and 4.0 are typical models of low-rise and mid-to-high rise, respectively. Findings suggest FAR 4.0 as the least efficient for energy planning while FAR 1.0 is the least economically viable model. The results support policy development on FAR monitory, and paradigm shifts for future urban development models, particularly for the small to medium-scale residential compounds in cities.
Robust control of floral meristem determinacy by position-specific multifunctions of KNUCKLES

Significance In floral meristem (FM), the transcription factor (TF) WUS and the secreted peptide CLV3 form a feedback loop to maintain robust stem cell activities. We found that the TF KNU is a temporally regulated repressor of WUS. However, how the spatial expression patterns of CLV3 and WUS are fully extinguished during floral organogenesis is unknown. Here, we show that KNU has position-specific multifunctions that achieve termination of robust FM. Besides repressing WUS in the organizing center, in the central zone, KNU directly represses CLV3 and inhibits WUS from sustaining CLV3. Furthermore, KNU represses CLV1 and disrupts WUS–WUS and WUS–HAM1 interactions. Thus, KNU plays an essential role to promote FM determinacy for the proper formation of floral reproductive organs. Floral organs are properly developed on the basis of timed floral meristem (FM) termination in Arabidopsis. In this process, two known regulatory pathways are involved. The WUSCHEL (WUS)-CLAVATA3 (CLV3) feedback loop is vital for the spatial establishment and maintenance of the FM, while AGAMOUS (AG)-WUS transcriptional cascades temporally repress FM. At stage 6 of flower development, a C2H2-type zinc finger repressor that is a target of AG, KNUCKLES (KNU), directly represses the stem cell identity gene WUS in the organizing center for FM termination. However, how the robust FM activity is fully quenched within a limited time frame to secure carpel development is not fully understood. Here, we demonstrate that KNU directly binds to the CLV1 locus and the cis-regulatory element on CLV3 promoter and represses their expression during FM determinacy control. Furthermore, KNU physically interacts with WUS, and this interaction inhibits WUS from sustaining CLV3 in the central zone. The KNU–WUS interaction also interrupts the formation of WUS homodimers and WUS–HAIRYMERISTEM 1 heterodimers, both of which are required for FM maintenance. Overall, our findings describe a regulatory framework in which KNU plays a position-specific multifunctional role for the tightly controlled FM determinacy.
Physico-chemical characterization of domestic wastewaters in the "Vie-Nouvelle" agglomeration, Cotonou, Benin

Wastewaters are characterized by a high variability of flow and composition according to its origin. The objectives of this study were to evaluate the daily variation of the pollutants load from domestic wastewater in "Vie-Nouvelle" agglomeration in the city of Cotonou. In practice, samples were collected over 24 hours with one sample every hour, at the entrance of wastewater treatment plant of the agglomeration. Various parameters were measured at laboratory. Determination of methods specific to each parameter was used. The results show that these wastewaters are characterized by a great pollution variability during the diurnal period of day. The pollutant load showed the following variations : pH values ranging: 7.1 – 7.3 (7.2 ± 0.1 for average); conductivity: 555 - 953 (804 ± 112) μS/cm; turbidity:139 - 238 (192 ± 27) NTU; COD: 675 - 1,983 (1,250 ± 350) mg O 2 /l; BOD5: 261 - 440 (1,257 ± 350) mg O2/l; NH4+: 18 - 34 (24 ± 5) mg/l; NTK: 36 – 78 (57 ± 12) mg/l; PO 4 3- : 6 – 18 (13 ± 4) mg/l; PT: 6 – 18 (13 ± 4) mg/l; Al: 3,998 – 8,508 (5,990 ± 1,338) μg/l; Cd: 0.5 – 6 (2 ±1 ) μg/l; Co: 1 – 3 (1 ± 1) μg/l; Cr: 19 – 110 (40 ± 25) μg/l; Cu: 113 – 615 (224 ± 135) μg/l; Fe: 3,232 – 16,842 (6,905 ± 3,846) μg/l; Mn: 114 – 452 (211 ± 90) μg/l; Ni: 18 – 85 (36 ± 17) μg/l; Pb: 52 – 243 (101 ± 50) μg/l; and Zn: 411 – 2,490 (908 ± 538) μg/l. These wastewaters do not comply with the discharge standards. They are moderately biodegradable and required denitrification and dephosphatation treatment processes before their release into aquatic ecosystems. Keywords : Domestic wastewater, wastewater variation, daily variation, pollution load, physico-chemical parameters.
Systematic Vandermonde CODEC PE for Erasure Codes

A systematic Vandermonde CODEC PE for erasure codes is proposed in this paper. The algorithm of the proposed CODEC PE is constructed by the Toeplitz matrix's characteristic first. Then split the decoding matrix into several small matrixes based on different scenarios. With that, the decoding operation can optimize to fixed parameters saved in memory and fetch to do the simple calculations when needed. After the combinatorial operation, the CODEC PE will give the final output. The PE is designed to work for both encoding and decoding with the same module but for different data and operations. The PE number is configurable to have the best performance in different erasure codes “r” situations and backward compatible by the control of the config module. The hardware architecture is fully verified at RTL level and synthesized with GF 12nm technology lib and simulation results showed 73.5% to 79.8% speed advantages compared to Gaussian elimination.
Briquetes de sementes de açaí : caracterização da biomassa e influência dos parâmetros de temperatura e pressão de produção na qualidade físico-mecânica e energética

Resumo A agroindústria, alavancada pela alta demanda dos produtos do açaí, promove impacto ambiental por meio da geração de resíduos em diversos locais da Amazônia. O uso com fins bioenergéticos tem a capacidade de mitigar esse cenário. Assim, o objetivo do estudo foi caracterizar a biomassa de sementes de açaí e estabelecer os parâmetros técnicos de temperatura e pressão de trabalho para a produção de briquetes de qualidade física, mecânica e térmica. Foram estudadas as temperaturas de 120, 140 e 160 ° C e as pressões de 15, 20 e 25 MPa. Analisamos a resistência mecânica à compressão dos briquetes, a taxa de absorção de água, a taxa de expansão volumétrica e energética e a densidade aparente. Para a caracterização de in naturasementes, a análise centesimal, a composição química (teores de extrativos, holocelulose e lignina), maior, menor e valor calorífico útil foram determinados. A análise aproximada indicou resistência térmica da biomassa, potencial de queima direta e conversão por processos termoquímicos. O teor de lignina pode aumentar a resistência à compressão dos briquetes produzidos em altas temperaturas. Observou-se que a temperatura teve mais influência nas características dos briquetes avaliados do que a pressão. A resistência à compressão foi maior nos briquetes de 160 ° C e 15MPa, indicando que a lignina funciona como um ligante nesta temperatura; entretanto, com a melhora da pressão, a resistência não é favorecida devido ao limite de resistência à compactação. A taxa de absorção de água diminuiu com o aumento da pressão e a temperatura foi estatisticamente afetada nos briquetes de 140 ° C. Observamos valores de expansão volumétrica em consonância com outros encontrados em biocombustíveis densos da literatura. Além disso, a densidade aparente e a densidade de energia foram favorecidas pela melhora da pressão, e a temperatura auxiliou no aumento da densidade aparente. Além disso, os briquetes produzidos apresentaram ganho na densidade aparente em relação aobiomassa in natura e possuía densidade energética comparável ao carvão e adequada para coqueima em caldeiras.
X-ray diffractometer

An X-ray diffraction apparatus, from the incident optical system (22) emits X-rays incident on the specimen support means is supported on a sample (60) (24), the diffracted X-rays from here light receiving optical system (26) is detected. Incident optical system having an X-ray source (66) and a multilayer film mirror (61). Specimen support means of the posture control means (36, 40) in accordance with the embodiment of the sample normal line (61) parallel to the first rotation centerline (32) of the sample maintained in a state of the first posture, in accordance with perpendicular manner to maintain the switching state of the second posture. When a sample is maintained at the first position when the receiving optical system is rotated about the first rotation center line, on the inner surface of the diffraction measurement can be performed. On the other hand, when the sample maintained in the second posture the same light receiving optical system is rotated, the outer surface can be diffractometry. Accordingly the present invention using X-ray diffraction apparatus may be in-plane diffraction measurement.
The Words of Affectivity. Affect, Category, and Social Evaluation Norms for 400 Polish Adjectives

Emotional adjectives can be grouped into two main categories: denoting and connoting stable (personality) traits and denoting and connoting transient (mood) states. They relate closely to the concept of affectivity, which is a pervasive tendency to experience moods of positive or negative valence. They constitute a rich study material for personality and affect psychology and neuroscience. Thus, this study was designed to establish a normed list of emotional adjectives with ratings encompassing four dimensions: emotional valence (positive or negative), emotional arousal (low-arousing or high-arousing), category (state, trait, and hybrid), and social judgment (competence, morality, and mixed). The adjectives were preselected based on previous broad Polish norming studies, personality and mood questionnaires, and a dictionary study. The results of the study were drawn from 195 participants who rated 400 adjectives that were chosen based on similar linguistic variables, such as frequency and word length. The dataset measures were proven to be stable and reliable. Correlations between the emotional valence and state-trait, valence and competence-morality, and emotional arousal and competence-morality dimensions were found. The study was successful in preparing a dataset of well-categorized (state, trait, and hybrid) positive and negative adjectives of moderate to high arousal ratings. Since the words were matched on linguistic variables, the set provided useful material that can be readily used for research into the effects of the category and emotional dimensions on language processing and as a basis for new personality questionnaires and mood checklists. The dataset could also be seen as a supplement for broader sets of published normed materials in Polish that link emotion and language.
Biomechanical Comparison of Tibial Plateau Leveling Osteotomy Performed With a Novel Titanium Alloy Locking Plate Construct vs. an Established Stainless-Steel Locking Plate Construct

A novel canine tibial plateau leveling osteotomy (TPLO) fixation device was recently developed with design features such as titanium alloy (TA) material, distal monocortical screw fixation, and a point contact undersurface specifically targeted to reduce surgical site infection rates by ensuring tissue perfusion under the plate. The strength of the novel TPLO construct was compared with that of a predicate stainless steel (SS) locking plate construct with bicortical screws in 16 paired cadaveric canine limbs. The mean loads to failure were 716.71 ± 109.50 N (range 455.69–839.69 N) and 629.50 ± 176.83 N (range 272.58–856.18 N) in the TA and SS groups, respectively. The average ratio of the loads to failure of the paired specimens was 1.18 (p = 0.031). No failure of the TA constructs involved the distal fixation with monocortical screws. Substantial mechanical equivalence of this novel TA monocortical/bicortical fixation construct to an established SS bicortical screw fixation construct is demonstrated. Clinical investigation of potential merits of this novel TA, monocortical/bicortical locking screw/plate system is now warranted.
Exergames and Nature

Exergaming provides the opportunity to have fun while exercising, with accompanying technology guiding and enhancing the experience. Exergames often contain some elements of nature and outdoor activities, though it is not well understood how engaging and effective these elements are to users. This paper presents an exploratory self-study of experiences with three exergames that include or encourage outdoor activity: Walkr, Zombies Run! , and Pokémon GO. The paper outlines the experiences of the participants, summarizing common and different elements of their interactions with the exergames. It provides in-depth examination of select elements of the game play as they relate to engagement with nature. Finally, it provides insights on ways that exergames’ elements have promise to engage users with nature.
Identification and Characterization of Staphylococcus aureus 16S rRNA gene isolated from different Food Specimens from South Indian Region

Staphylococcus aureus (S. aureus) associated food-borne diseases have global impact on human health. Genome wide analyses have shown that S. aureus contains specific endotoxin expressing gene and produce toxic proteins which is responsible for food contamination. Appropriate detection of pathogens is one of the major tool to avoid infection rate and reduce the health and socio-economic burden to human being. In addition, inappropriate handing the specimens, misdiagnosis and limited standard medical support could directly influence the infection rate. The objective of this study was to identify S. aureus from different food specimens from Hyderabad, India. A total of 70 random bacterial nutrient agar medium pure plates were made based on different morphological appearance of bacterial colonies. Preliminary identification of S. aureus based on standardized morphological method showed specific golden yellow colonies. Biochemical assay also verified bacterial specimens. Furthermore, molecular characterization was performed on the basis of polymerase chain reaction (PCR) and sequencing of 16S rRNA gene of S. aureus. Newly sequenced 16S rRNA gene sequences showed 100% homology to S. aureus, analyzed using NCBI-BLAST tool. The phylogenetic analysis and nucleotide base composition studies performed using 39 sequences of 16S rRNA gene from different isolates of Staphylococcus, including Staphylococcus aureus. For the purpose, 16S rRNA gene sequences were retrieved from the NCBI in FASTA format. The phylogenetic analysis was performed using Maximum Likelihood method and revealed the relationships and percent similarity of Staphylococcus aureus 16S rRNA gene.
Structural and Biophysical Studies of the Role of Stromal Interaction Molecules STIM1 and STIM2 in Initiating Store-operated Calcium Entry

Store-operated calcium entry (SOCE) is the major Ca entry pathway in most non-excitable cells maintaining prolonged elevation of cytosolic Ca levels required for gene transcription. SOCE is activated by the loss of endoplasmic reticulum (ER) Ca through stromal interaction molecules (STIM), ER-membrane associated Ca sensors. In humans, STIM1 and STIM2 share 65% sequence similarity but differentially regulate SOCE. Biophysical studies on the luminal Ca-binding region suggests that STIM2 EF-SAM is more stable than STIM1. The NMR structure of Ca-loaded STIM2 EF-SAM determined in this work suggests a more stable SAM and a tighter EF-hand and SAM interaction in STIM2 may be account for its higher stability. Chimeric swapping of the EF-hand and SAM domains generates an unstable ES211. Introducing ES211 into cherryFP-STIM1 shows constitutive puncta which activate SOCE independent of ER depletion. The current work demonstrates that the instability of the EF-SAM plays an important role in regulating SOCE initiation.