Miracle-dz/UniFAR-FTUs huggingface dataset:
One-Day Activities for K-12 Face-to-Face Outreach

The recent successes of Computer Science Education Week and code.org's Hour of Code have meant that more K-12 students than ever are being given an authentic, engaging and eye-opening exposure to the wonders of computer science. There are resources aplenty to help high school and college faculty with outreach. These range from easy-to-learn, open-ended programming environments (Scratch, Alice, Snap! ), to online coding challenges (code.org, Lite-bot), to non-computer activities with live performances (CS Unplugged, cs4fn), to having the entire outreach experience delivered "in a box", thanks to NCWIT. We wanted to bring educators together to share experiences with what they've done specifically with a one-day event, given these vast resources. Now that there are so many online coding experiences, it is enough to shuttle young students into a computer room, point their browser at one of these experiences, and answer questions as they come up? Is it important to include hands-on and hands-off (e.g., nifty demos, inspiring talks) components, and if so, in what order? What do different demographics find the most engaging? Is there any chance that we can do "damage", since these highlight-reel experiences might over-simplify how hard some of the problems are, and that not every important result has a flashy payoff? Do some of the early experiences leave students with the impression that computer science is only (say) apps, interactive multimedia programs or solving mazes? Finally, when it's over, what follow-up is appropriate? Participants on the panel will share best practices, common pitfalls, and advice.
Hypoxia inducible factor-1-dependent up-regulation ofBMP 4 mediateshypoxia-induced increaseofTRPC expression in PASMCs

Hypoxia inducible factor-1-dependent up-regulation ofBMP4mediateshypoxia-induced increaseofTRPC expression in PASMCs
Content-based image retrievals based on generalised gamma distribution and relevance feedback mechanism

The modern technological developments have made significant strides in the usage of internet and made it possible to store and access voluminous data across the globe. These developments have brought certain disadvantages with regard to retrieval of images of interest and also while storing the images. These retrievals play a crucial role in the areas like content-based image retrievals CBIR. CBIR has wide advantages in areas like security, medical domain where based on the features, the images are to be retrieved. It is therefore necessary to retrieve the interest of images based on certain keyword or features which helps towards faster retrieval of the images. Since the number of images available in the internet is increasing, it is therefore necessary to extract the images based on relevance and query. This paper mainly focuses on the retrieval of the images based on generalised gamma distribution GGD. The technique employed in this paper is based on the input query and extracting the vital information based on the relevancy. The performance of the developed model is tested using metrics like precision and recall. The methodologies also compared with the available existing methods based on GMM and skew GMM using evaluation metrics. The proposed model exhibited significant performance.
Stereotactic Body Radiotherapy in the Treatment of Adrenal Metastases

Objectives:To evaluate the dosimetry, clinical outcomes, and toxicity of patients treated with stereotactic body radiotherapy (SBRT) for adrenal metastases. Materials and Methods:From February 2009 to February 2011, a total of 13 patients were treated with SBRT for metastases to the adrenal glands. Median age was 71 years (range, 60.8 to 83.2). Primary sites included lung (n=6), kidney (n=2), skin (n=2), bladder (n=1), colon (n=1), and liver (n=1). Nine patients had metastases to the left adrenal gland and 4 to the right. The median prescribed total dose was 45 Gy (range, 33.75 to 60 Gy), all in 5 fractions. Results:Median follow-up for living patients was 12.3 months (range, 3.1 to 18 mo). Twelve of the 13 patients (92.3%) were evaluable for local control (LC). The crude LC rate was 100%, with no cases of local or marginal failure. Two patients had a complete response to treatment, 9 patients had a partial response, and 1 patient displayed stable disease. One-year overall survival and distant control were 62.9% and 55%, respectively. Median OS was 7.2 months (range, 2 to 18 mo). Grade 2 nausea was noted in 2 patients. Conclusions:SBRT seems to be a safe and effective measure to achieve LC for adrenal metastases.
EHPnet: Black Sea Change

Background: Epstein-Barr virus has been proved to be associated with many of the human malignancy including gastric carcinoma, one of the most important human malignancies in the world. There has been no study about the presence of EBV in gastric adenocarcinoma in Iran. Methods: We examined the presence of EBV in 273 formalin fixed paraffin-embedded cases of gastric carcinoma from Cancer institute of Tehran University, from 1969 to 2004. In situ hybridization of EBV-encoded small RNA-1 (EBER-1) was conducted. The strain of positive cases was examined by means of polymerase chain reaction and/or restriction fragment length polymorphism analysis. Results: We found 9 (3%; 95% CI = 1–5%) EBV positive cases. The gender difference was not statisticaly significant. The proportion of EBV-GC cases in diffuse type was higher than intestinal type (OR = 0.08; 95% CI = 0.002–0.64). EBV-GC cases had no relation with age, location and invasion. Six out of 9 EBV-GC cases were born during the period between 1928 and 1930. All 9 cases were Type A. Prototype F was seen in 6 out of 8 cases. Type "i" was found in 8 cases and type I in 1 case. XhoI+ and XhoIpolymorphism accounted 6 and 3 of the cases, respectively. Conclusion: Our study is the first to describe the frequency of EBV-GC in Iran and the Middle East, highlighting a very low prevalence with specific clinicopathologic features. The predominance of EBV-GC birth year in a fixed period, suggests that EBV infection or other events at early childhood may be related to the development of EBV-GC later in the life. The predominance of the type "i" and XhoI+ cases are contradictory to other studies in Asia and is similar to what is reported from Latin American countries. Published: 15 July 2007 Diagnostic Pathology 2007, 2:25 doi:10.1186/1746-1596-2-25 Received: 26 April 2007 Accepted: 15 July 2007 This article is available from: http://www.diagnosticpathology. org/content/2/1/25 © 2007 Abdirad et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Comparative Analysis of Simultaneous Ascending Auctions and Combinatorial Auctions

3 Comparison of Auction Designs 8 3.1 Efficiency . 8 3.1. 1 Efficiency in the Auction Market . 9 3.1. 2 Efficiency in the Post-Auction Market . 10 3.2 Revenue . 11
Liposome-Mediated Gene Transfection of Endothelial Nitric Oxide Synthase Reduces Endothelial Activation and Leukocyte Infiltration in Transplanted Hearts

Background—During cardiac ischemia-reperfusion injury, neutrophilic infiltration of the myocardium is mediated by adhesion molecule expression on activated coronary endothelium. Nitric oxide inhibits neutrophil adhesion to endothelium in vitro by blocking the nuclear factor (NF)-&kgr;B-dependent transcription of adhesion molecules. We investigated whether intraoperative gene delivery of endothelial nitric oxide synthase (eNOS) into donor hearts before transplantation would have a similar effect on an entire organ. Methods and Results—In an allogeneic rabbit heart transplant model, liposomes complexed to the gene encoding eNOS were infused into the donor coronary circulation before transplantation. By 24 hours after transplantation, calcium-dependent nitrite production was significantly higher in eNOS-transfected donor hearts than in the 3 control groups: donor hearts transfected with empty plasmids alone, donor hearts treated with diluent only, and untransplanted native hearts. Intramyocardial neutrophil and T-lymphocyte populations were halved in eNOS-transfected hearts compared with control donor hearts (P <0.05). Moreover, the prevalence of NF-&kgr;B activation in microvascular endothelial cells and surrounding cardiac myocytes as well as endothelial vascular cell adhesion molecule-1 and intracellular adhesion molecule-1 expression were all significantly reduced in eNOS-transfected hearts compared with control donor hearts (P <0.01). Without immunosuppression, eNOS-transfected hearts survived longer than controls. Conclusions—Intraoperative liposome-mediated gene delivery of eNOS to donor hearts can result in early gene expression sufficient to reduce ischemia-reperfusion injury by inhibiting NF-&kgr;B activation, adhesion molecule expression, and the early infiltration of leukocytes, all of which may improve graft survival.
Bmc Complementary and Alternative Medicine Rat Models of Acute Inflammation: a Randomized Controlled Study on the Effects of Homeopathic Remedies

Background: One of the cardinal principles of homeopathy is the "law of similarities", according to which patients can be treated by administering substances which, when tested in healthy subjects, cause symptoms that are similar to those presented by the patients themselves. Over the last few years, there has been an increase in the number of pre-clinical (in vitro and animal) studies aimed at evaluating the pharmacological activity or efficacy of some homeopathic remedies under potentially reproducible conditions. However, in addition to some contradictory results, these studies have also highlighted a series of methodological difficulties.
Income Mobility and Financial Disadvantage: Australian Children

his article provides the first Australian estimates of income mobility transitions among Australian children over a three year period. The results suggest that there is considerable income mobility but that, in the vast majority of cases, the shift is not dramatic. Transitions from the top to the bottom of the income spectrum, and vice versa, are very rare. Using a financial disadvantage line set at the cut-off point for the bottom quintile, the study also showed that about twelve per cent of all Australian children were in persistent financial disadvantage, experiencing financial disadvantage in all of the three years. An estimated 28 per cent of Australian children experienced financial disadvantage in at least one of the three years — about 40 per cent more than the proportion experiencing financial disadvantage in annual ‘snapshots’. Comparison with overseas studies suggests that Australia does not appear to have greater mobility, perhaps contrary to the Australian perception of the ‘fair go’. Analysis of the factors precipitating transitions into and out of financial disadvantage suggests that the emphasis by the Federal Government on requiring welfare recipients to work is an appropriate policy response, which may help to reduce the proportion of children who remain disadvantaged for extended periods of time. The extent of income mobility and financial disadvantage among children is widely regarded as an important social issue. In Australia, the then Prime Minister, Bob Hawke, focussed attention on this issue in the 1980s, when promising that ‘by 1990 no child shall live in poverty’. In Europe, the goal of promoting social inclusion has led to regular assessment of financial disadvantage and in such countries as the UK and Ireland there are strong anti-poverty initiatives in place (Department of Work and Pensions, 2002; Atkinson
Impact of hydroxyethyl starch 70/0.5 on acute kidney injury after gastroenterological surgery

Background Previous studies reported a higher mortality risk and a greater need for renal replacement therapy in patients administered hydroxyethyl starch (HES) rather than other fluid resuscitation preparations. In this study, we investigated the association between 6% HES 70/0.5 use and postoperative acute kidney injury (AKI) in gastroenterological surgery patients. Methods We conducted retrospective full-cohort and propensity-score-based analyses of patients who underwent gastroenterological surgery between June 2011 and August 2013 in a Japanese university hospital. The study sample comprised 66 AKI and 2,152 non-AKI patients in the full-cohort analysis and 35 AKI and 1,269 non-AKI patients in the propensity-score-based analysis. Propensity scores were calculated using an ordered logistic regression model in which the dependent variable comprised three groups based on HES infusion volumes (0, 1–999, and ≥ 1,000 ml). The association between HES groups and postoperative AKI incidence was analyzed using multiple logistic regression models. Other candidate independent variables included patient characteristics and intraoperative measures. Results In the full-cohort analysis, 40 (60.6%) AKI patients were diagnosed as "risk", 15 (22.7%) as "injury," and 11 (16.7%) as "failure". In the propensity-score-based analysis, the corresponding values were 22 (62.9%), 8 (22.9%), and 5 (14.3%). There was no significant association between total infused HES and postoperative AKI incidence in either the full-cohort or the propensity-score-based analysis (P = 0.168 and P = 0.42, respectively). Conclusions AKI incidence was not associated with clinical 6% HES 70/0.5 administration in gastroenterological surgery patients treated at a single center.
Effective Teaching & Teaching Evaluation Practices: Canadian University Geography Departments

In this thesis teaching evaluation practices in Canadian university geography departments are examined. The objective of this research is to identify good practices for teaching evaluation that can be applied within geography departments at Canadian universities and may be applicable to other departments and within other countries. In order to meet this goal a number of research questions were identified. These include: 1. What is effective teaching in higher education? ; 2. What is effective teaching within the discipline of geography in higher education? ; 3. How and why is teaching evaluated in higher education? ; 4. What is the breadth of teaching evaluation practices currently used in geography departments within Canada? ; 5. How are the results of teaching evaluations used to enhance teaching quality within the discipline of geography in higher education? ; 6. How are the results of teaching evaluations used to reward teaching excellence within the discipline of geography in higher education? ; and, 7. What are 'good' teaching evaluation practices within the discipline of geography in higher education? A thorough review of the literature resulted in the development of a conceptual framework for effective teaching and for effective teaching evaluation. Both of these frameworks were tested using empirical data. The empirical data were collected from a national-level survey of geography departments across Canada (n=10), oral interviews with chairs of Canadian geography departments (n=23) and oral interviews with individuals suggested by chairs of Canadian geography departments (n-11). The research provided validation of the conceptual framework of good teaching. This framework identified eight parameters of good teaching: discipline knowledge, course organization, delivery of instruction, student/instructor interaction, assessment tasks, administration, professional development and skill development. The results from the research suggested that the original conceptual framework of effective teaching evaluation was too simplistic. It also demonstrated that effective teaching evaluation occurs within the demographics and culture of place which results in the creation of an environment of evaluation. In this environment of evaluation seven parameters of an effective teaching evaluation system are identified including: defining good teaching, operationalizing good teaching, defining purpose of teaching evaluation, using a multiplicity of tools, employing an iterative teaching evaluation cycle, including a system of awards and including a mechanism for teaching enhancement. In the future these conceptual frameworks can be tested in a variety of other disciplines and within different countries. The primary stakeholder in this research was chairs of geography departments. There are a number of other stakeholders described in this research and the frameworks could be tested from their perspectives.
A questionnaire based study to assess the interns’ knowledge about the brand names of drugs routinely prescribed in a tertiary care hospital in Kerala, India

Background: The gap in the knowledge of interns between brand names, generic name and indication of a drug can lead to unwanted clinical consequences. This study was conducted to assess the knowledge of interns at a tertiary care hospital regarding the generic name and indications of the routinely prescribed brand names of drugs.Methods: In this study, interns were required to write whether they prescribed the brand names mentioned in the questionnaire in the preceding six months, their generic name and the indication for their use. Results were expressed using descriptive statistics.Results: All brands except Zovobact SB was prescribed by more than 50% of interns in the preceding six months. The generic equivalents were correctly identified by good percentage of interns for Hicet (100%), Asthalin (95%), Cifran (90%) but the percentage of correct answers was low for other brands. For combination brands, correct generic names of all components were identified by more than 50% of interns for oflox TZ (93%), Septid D (68%) and Losar H (68%). The percentage of correct response for the indication of the brands was satisfactory for Hicet (100%), Asthalin (98%), Cifran (98%), Zerodol P (100%), Cyclopam (100%), oflox TZ (100%), Losar H (98%), Septid D (98%) but was inadequate for Taxim O (48%), Betaloc (33%), Valium (23%), Diamox (0%), Quadriderm (31%) and Zovobact SB (31%). Conclusions: This study identified lacunas in the knowledge of interns regarding generic equivalents and indications of brand names. Strategies to overcome the problem should be devised to ensure patient safety.
Population biology and harvest of the coral reef surgeonfish Acanthurus lineatus in American Samoa

-The herbivorous blue banded surgeonfish, Acanthuru8 line atu8, was a major species harvested on coral reefs in American Samoa, ac counting for 39%by weightofartisanal catches in 1994. Spawning occurred year-round but peaked during the aus tral spring and summer (October-Feb ruary). A dense pulse of recruits (0.4 0.6 recruitslm 2) settled onto the outer reefflat in March-April. Apparentsur vival was low during the first year but increased thereafter (80%/year). The fish were strongly site-attached on a daily basis, but an estimated 60% ofthe adults switched territories at least once during a 3-year period, thereby negat ing attempts to estimate mortality through attrition rates ofmarked indi viduals. Estimates of fish condition changed through the year, generally paralleling seasonal changes in a suite ofenvironmentalfactors. The fish grew rapidly, attaining 70-80% of their to tal growth during their first year, fol lowed by slow growth and long life (up to 18 years), characteristics that con founded standard growth analyses by producing age-specific growth para meters. Growth was best described by a two-phase von Bertalanffy growth curve for ages 0-3 (K=1.ll and ages 4 18 (K=0.12,
The Linked Selection Signature of Rapid Adaptation in Temporal Genomic Data

Populations adapt to selection on polygenic traits through subtle allele frequency changes scattered throughout the genome. Detecting such changes from population genomic data is quite difficult, as these small changes can look like genetic drift. Buffalo. The majority of empirical population genetic studies have tried to understand the evolutionary processes that have shaped genetic variation in a single sample taken from a present-day population. However, genomic data collected over tens of generations in both natural and laboratory populations are increasingly used to find selected loci underpinning adaptation over these short timescales. Although these studies have been quite successful in detecting selection on large-effect loci, the fitness differences between individuals are often polygenic, such that selection leads to allele frequency changes that are difficult to distinguish from genetic drift. However, one promising signal comes from polygenic selection’s effect on neutral sites that become stochastically associated with the genetic backgrounds that lead to fitness differences between individuals. Previous theoretical work has established that the random associations between a neutral allele and heritable fitness backgrounds act to reduce the effective population size experienced by this neutral allele. These associations perturb neutral allele frequency trajectories, creating autocovariance in the allele frequency changes across generations. Here, we show how temporal genomic data allow us to measure the temporal autocovariance in allele frequency changes and characterize the genome-wide impact of polygenic selection. We develop expressions for these temporal autocovariances, showing that their magnitude is determined by the level of additive genetic variation, recombination, and linkage disequilibria in a region. Furthermore, by using analytic expressions for the temporal variances and autocovariances in allele frequency, we demonstrate that one can estimate the additive genetic variation for fitness and the drift-effective population size from temporal genomic data. We also show how the proportion of total variation in allele frequency change due to linked selection can be estimated from temporal data. Overall, we demonstrate that temporal genomic data offer opportunities to identify the role of linked selection on genome-wide diversity over short timescales, and can help bridge population genetic and quantitative genetic studies of adaptation.
THE RELATION BETWEEN BULK DENSITY, AVAILABLE WATER CAPACITY, AND AIR CAPACITY OF SOILS

Summary The effect of bulk density on moisture content at 50 mb tension in four soils of different textures was studied. The volumetric water content increased linearly with bulk density over a wide range of densities. Depending on texture, a maximum bulk density was reached above which continued compaction decreased the water content. This is shown to be the point at which the air capacity of the soil at this tension approaches zero. Accepting that the gravimetric wilting point depends mainly on texture, the available water capacity varies in a manner similar to the 50 mb water content. If the relationships described are valid in the field, the available water capacity and air capacity may be optimized using cultivation techniques to adjust the bulk density. The available water capacity of coarse-textured droughty soils may be increased by increasing the bulk density provided that the air capacity remains above acceptable lower limits (10–15 per cent). Conversely, the air capacity of compacted soils with large available-water capacities could be increased by reducing the bulk density to a value corresponding to an acceptable available-water capacity. In very compacted soils a decrease in bulk density will benefit both available-water capacity and air capacity.