Miracle-dz/UniFAR-FTUs huggingface dataset:
Analisis cross reactivity protein precursor membrane (prM) virus dengue endemik Indonesia dengan pendekatan imunoinformatik

Infeksi demam berdarah dianggap sebagai salah satu masalah kesehatan utama di Indonesia dan disebabkan oleh virus dengue. Kemampuan reaksi silang pada virus dengue dapat memperparah jika terjadi infeksi lainnya. Protein precursor membrane (prM) pada virus dengue merupakan bagian yang rentan akan terjadinya antibody dependant enhancement dan evolusi gen prM berubah setiap tahunnya. Studi ini bertujuan untuk menganalisa reaksi silang gen prM dari virus dengue yang endemis di Indonesia. Sebanyak 96 data sampel dari National Center for Biotechnology Information digunakan pada studi ini. Prediksi antigenisitas dengan metode B-cell epitope prediction lalu di lanjutkan proses analisis reaksi silang menggunakan Basic Local Aligntment Search Tool (BLAST) dengan perbagian 20 protein prM pada setiap genotype virus yang memiliki antigenisitas yang spesifitasnya 0,8. Hasil dari studi ini didapatkan 4 prediksi antigenisitas dan beberapa hasil reaksi silang terhadap protein lain seperti anti-SARS-CoV-2 immunoglobulin heavy chain, human immunodeficiency virus type I enhancer-binding protein 2, insulin receptor substrate like protein partial, cerebellar-degeneration-related antigen. Pada studi ini ditemukan adanya perubahan prediksi antigenisitas dari gen prM virus dengue yang muncul setiap tahun dan adanya reaksi silang dengan protein lain.
Epigenetics and its essence in understanding human growth, development and disease

Epigenetics is a scientific discipline encompassing the genetic and non-genetic related perspectives of heritable phenotypic modifications of whose aetiologies include behavioural, anthropogenic, environmental, metabolic and spatiotemporal variables. Behavioral epigenetics examines how epigenetics shapes animal and human behaviour to explicate how nurture moulds nature; nature prefers to biological heredity and nurture prefers to occurrrences in the environment and hereditary during the lifespan of all individuals. Behavioural epigenetics features how experiences and the environment produce individual disparities in behaviour, cognition, personality, and mental health influence gene expression. Epigenetic gene regulation relates to modification of DNA sequence and histones as well as DNA methylation. These epigenetic alterations effect the growth of neurons in the developing brain and functional modification of neurons in the developed brain, with resultant significant alterations in neuron morphology. Epigenetic changes occur in the developing fetus and throughout the lifespan of an individual, with alterations in individual traits and transgenerational inheritance. Epigenetics is associated with heritable changes in gene actions and these are not due to DNA sequence alterations. Epigenetics may be termed sustained, long-run changes in the transcription veracity of a heritable or non-heritable cell. DNA methylation and histone alteration are mechanisms which modify gene expression without changing the underlying DNA sequence. Gene expression is driven by repressor protein actions which bind to DNA silencer regions.DNA methylation turns a gene ''off'' culminating in genetic information impairment to be read from DNA, but extricating the methyl tag can turn ''on'' the gene. Histone alteration defines the packaging of DNA into the chromosomes; and.these changes influence gene expression. This review provides the latitude to examine the extant information in the universal characterizations of epigenetic formulations, such as ageing, susceptibility to pollutant and irritant exposure.
Monte Carlo interior models for Uranus and Neptune

To explore a greater realm of model phase space than has previously been mapped, we generate randomly chosen interior models for Uranus and Neptune. The models are constrained by the observed mass, rotation rate, radius, and gravitational moments of the two planets. New models with a composition gradient in the outer third of the planetary radius are found for both planets. Such composition gradients may play a significant role in controlling the internal heat flow. In agreement with previous models, we find that the pressure-density relation for the central third of both planets is consistent with either ice or a mixture of materials with a similar equation of state. While the range of allowed models is now somewhat greater, the principal conclusions drawn from traditional interior modeling techniques are robust.
Characteristics and prognosis of distant metastasis after primary treatment for early‐stage extranodal nasal‐type natural killer/T‐cell lymphoma from the China Lymphoma Collaborative Group database

This study aimed to investigate the characteristics and prognosis of distant metastasis (DM) after primary treatment for early‐stage extranodal nasal‐type natural killer (NK)/T‐cell lymphoma (ENKTCL). A total of 1619 patients from the China Lymphoma Collaborative Group database were retrospectively reviewed. The cumulative incidence of DM was assessed using Fine and Gray's competing risk analysis. The correlation between DM sites was evaluated using phi coefficients, while DM sites were classified using hierarchical clustering. Regression analysis was used to assess the linear correlation between DM‐free survival (DMFS) and overall survival (OS). The 5‐year cumulative DM rate was 26.2%, with the highest annual hazard rate being in the first year (14.9%). The most frequent DM sites were the skin and soft tissues (SSTs, 32.4%) and distant lymph nodes (LNs, 31.3%). DM sites were categorized into four subgroups of distinct prognosis — distant LN, SST, extracutaneous site, and lymphoma‐associated hemophagocytic lymphohistiocytosis. SST or distant LN, solitary metastasis, and late‐onset DM demonstrated a relatively favorable prognosis. Contemporary chemotherapy significantly decreased DM rates and improved DMFS. Decreased DM rates were further associated with increased OS probabilities. Our findings improve the understanding of the variable clinical behaviors of early‐stage ENKTCL based on four distinct DM sites and thus provide guidance for future therapeutic decisions, metastatic surveillance, and translational trial design.
Radiatively limited dephasing in InAs quantum dots

We measure the dephasing time of the exciton ground-state transition in In1−xGaxAs quantum dots using a sensitive four-wave mixing technique. We find experimental evidence that the dephasing time is given only by the radiative lifetime at low temperatures. We demonstrate the tunability of the radiatively limited dephasing time from 400 ps up to 2 ns in a series of annealed In1−xGaxAs quantum dots with increasing quantum-confinement energy from 69 meV to 330 meV.
A new class of electrically small antennas

This paper describes a new class of electrically small antennas, of which the principal advantages are the resistive input impedance, the radiation resistance transformation which may be obtained within the structure, and the variety of shapes which the antennas may take. The antennas incorporate resonant half-wave windings, and a simple transmission line theory is presented by which antenna efficiency and bandwidth may be calculated. Experimental methods and results are described for antennas in the order of 0.01 wavelength in height and 0.05 wavelength in diameter.
Is Gender Based Violence Related to Sanitation? A Case Study of Patongo Town Council, Uganda

Gender-based violence is a global problem that affects women of all races, colours and creeds. The Sustainable Development Goals also emphasise the need to pay special attention to women and girls regarding hygiene and sanitation. While lack of sanitation is not the main cause of gender-based violence, it is a significant contributor to its occurrence. Several studies have been published in the literature on violence against women in different parts of the world. Still, this study focused on Patongo Municipality, Agago District, Northern Uganda, where few studies have been conducted. This study investigated whether gender-based violence was linked to sanitation. The study focused on sanitation practices and gender-based decision-making. It also examined gender-based violence related to sanitation, including concerns, worries and fears, and economic violence. In general, the study looked at how sanitation practices may be linked to gender-based violence. Sanitation practice is gendered and mainly revolved around excreta, pregnancy and menstrual hygiene. These practices are the result of education, culture and economic status in the household. Therefore, these sanitation practices are shaped by different norms and roles among women and men. Men and women expressed stress related to sanitation, with women expressing it more. This stress results from the location of the latrine, its accessories and the taboos around menstruation and pregnancy. This study further explores the issue of safety, privacy, protection and shame concerning sanitation practices. Roles and responsibilities are gendered. For example, men decide on the location and financing of the latrine, while women are responsible for the daily maintenance of the latrine. Due to their education and socioeconomic status, women sometimes decide on the latrine's location.The community had different perceptions of gender-based violence. For them, gender-based violence referred only to sexual and physical violence. However, the study found various forms of gender-based violence in the community, including Sexual, physical, emotional and economic violence. Although these forms existed in the community, the study concluded that gender-based violence was not related to sanitation.
A High Resolution, High Sensitivity Channel Plate Image Intensifier for Use in Particle Spectrographs

Details are presented of an image intensifier for electrons using a channel plate, scintillator, and fiber optics combination, which gives a reduction in exposure time of several thousand compared to a photographic plate. During the course of the investigation, measurements were made on the characteristics of the channel plate for various electron energies and angles of incidence.
Enhancing learning on foreign‐accent adaptation with a combination of active training and passive stimulus exposure

Improvement on most perceptual tasks requires active performance of the target task during training. However, there has been little consideration of whether that active performance is necessary throughout the entire practice period. Suggesting that it is not, there is recent evidence that active performance on a simple frequency‐discrimination task, interleaved with passive stimulus exposures, can yield more learning than the active performance alone. The current study examines whether these findings extend to a speech‐learning task, specifically foreign‐accent adaptation. Native‐English speakers transcribed sentences spoken in English by non‐native speakers. Participants who performed the target task for half the training period and received passive stimulus exposures while performing a distracter task for the other half out‐performed participants who received the same amount of active training, but no passive exposures during the distracter task, suggesting that passive exposures enhanced learning. The .
Resonant diffusion of energetic electrons by narrowband Z mode waves in Saturn's inner magnetosphere

Banded emissions near 5 and 20 kHz are observed by the Cassini Radio and Plasma Wave Science (RPWS) instrument and are identified as Z mode waves in the regions where the plasma frequency is below the electron gyrofrequency. Using wave parameters derived from Gaussian fits to the measured power spectral density for narrow‐band Z mode waves and the ambient density and magnetic field information at L = ~4, we compute the bounce‐averaged diffusion coefficients for the Saturnian radiation belt electrons. Our results indicate that 5 kHz Z mode emissions can cause resonant scattering of electrons from ~2 MeV to tens of megaelectron volts, while 20 kHz waves can interact with electrons from hundreds of kiloelectron volts to ~2 MeV. In principle, the rate of momentum diffusion can be an order of magnitude larger than that of pitch angle diffusion and cross diffusion for electrons at equatorial pitch angles > ~10°, suggesting that Z mode waves on Saturn are responsible for local acceleration of radiation belt energetic electrons at intermediate pitch angles.
Eddy current losses in the armature of a superconducting turbine-generator

In this paper the authors analyze the eddy current losses in the armature winding of a two-pole and a four-pole turbine generators, making use of the vector potential algorithm. The ratio R ac /R dc has been evaluated for several configurations and the results show that the armature morphology can significantly affect its value. Such losses are due to eddy currents induced by E.M. F. dissymmetries present in large windings. This phenomenon causes an increase in the R ac /R dc up to values greater than 100.
On Multiplication Maps of Ample Bundles with Nef Bundles on Toric Surfaces

We show that the multiplication map of global sections of an ample line bundle and a nef line bundle on a projective toric surface is surjective. We also prove that on a Gorenstein toric 3-fold whose anti-canonical bundle is nef, the multiplication of global sections of an ample line bundle by those of the anti-canonical bundle is surjective.
BENDING, BUCKLING AND FREE VIBRATION ANALYSES OF NANOBEAM-SUBSTRATE MEDIUM SYSTEMS

This study presents a newly developed size-dependent beam-substrate medium model for bending, buckling, and free-vibration analyses of nanobeams resting on elastic substrate media. The Euler-Bernoulli beam theory describes the beam-section kinematics and the Winkler-foundation model represents interaction between the beam and its underlying substrate medium. The reformulated strain-gradient elasticity theory possessing three non-classical material constants is employed to address the beam-bulk material small-scale effect. The first and second constants is associated with the strain-gradient and couple-stress effects, respectively while the third constant is related to the velocity-gradient effect. The Gurtin-Murdoch surface elasticity theory is adopted to account for the surface-free energy. To obtain the system governing equation as well as corresponding boundary conditions, Hamilton’s principle is called for. Three numerical simulations are presented to characterize the influences of the material small-scale effect, the surface-energy effect, and the surrounding substrate medium on bending, buckling, and free vibration responses of nanobeam-substrate medium systems. The first simulation focuses on the bending response and shows the ability of the proposed model to eliminate the paradoxical characteristic inherent to nanobeam models proposed in the literature. The second and third simulations perform the sensitivity investigation of the system parameters on the buckling load and the natural frequency, respectively. All analytical results reveal that both material small-scale and surface-energy effects consistently stiffen the system response while the velocity-gradient effect weakens the system response. Furthermore, these sized-scale effects are more pronounced when the underlying substrate medium becomes softer.
Multifunctional terahertz filters designed by shape resonance

Terahertz transmission filters have been manufactured by perforating metal surface structures with various geometric shapes which all support near-unity transmission at specific frequencies determined by geometric shape, symmetry, polarization, and lattice constant. Our results show that the structures specifically designed by the shape resonance are extremely versatile, dependable, easy to control and easy to make the multifunctional filters.
Sustainable Beauty: Pengaruh Eco-Label, Product Attributes, Perceived Consumer Effectiveness (PCE), dan Environmental Awareness terhadap Green Purchase Behavior

Meningkatnya pencemaran lingkungan serta adanya urgensi untuk meningkatkan kepedulian lingkungan masyarakat Indonesia, menyebabkan perusahaan turut berkontribusi melalui penerapan green marketing. Sementara itu, sektor kosmetik di Indonesia saat ini sedang tumbuh signifikan. Green marketing juga turut diimplementasikan pada industri tersebut dengan munculnya berbagai merek kosmetik lokal yang mengusung konsep sustainable beauty. Gen Z menjadi salah satu faktor pendorong booming-nya industri kosmetik di Indonesia. Maka, pelaku bisnis sustainable beauty perlu mengetahui faktor-faktor yang dianggap berpengaruh terhadap green purchase behavior pada Gen Z. Penelitian ini mengidentifikasi beberapa faktor yang dianggap berpengaruh, melalui survei terhadap 335 responden yang dilakukan melalui kuesioner daring dan data dianalisis menggunakan Structural Equation Modelling (SEM). Hasil penelitian menunjukan bahwa faktor yang mempengaruhi green purchase behavior Gen Z terhadap produk green cosmetics merek lokal adalah eco-label, PCE, environmental attitude, dan ecological affection. Penelitian ini juga menunjukkan bahwa meningkatkan ecological affection dapat dilakukan baik secara langsung melalui PCE ataupun melalui environmental attitude terlebih dahulu.
Skill acquisition, coarticulation, and rate effects in a neural network model of speech production

This work describes a neural network model of speech motor skill acquisition and speech production that explains a wide range of data on contextual variability, motor equivalence, coarticulation, and speaking rate effects. Model parameters are learned during a babbling phase. To explain how infants learn phoneme‐specific and language‐specific limits on acceptable articulatory variability, the learned speech sound targets take the form of regions, or convex hulls, in orosensory coordinates. This leads to an explanation of coarticulation wherein the target for a speech sound is reduced in size based on context to provide a more efficient sequence of articulator movements. Furthermore, reduction of target size for better accuracy during slower speech (in accordance with Fitt’s law) leads to differential effects for vowels and consonants, as seen in speaking rate experiments that were previously explained by positing separate control processes for the two sound classes. The babbling process also naturally acc.
Women's Perspectives on a Reproductive Health Services Screening Question: An Alternative to Pregnancy Intention Screening

Background Current efforts to integrate reproductive health care into primary care in the United States involve assessing pregnancy intentions and reproductive goals, which are often not meaningful or attainable for some. Alternatively, we designed a reproductive health services-based screening question: “Can I help you with any reproductive health services today, such as preventing pregnancy or planning a healthy pregnancy? ” In this study, we describe women's interpretations of this question as part of a larger study, exploring perspectives on reproductive health care quality in primary care. Materials and Methods We utilized a third-party research firm to recruit New York women of reproductive age (18–45), who visited a primary care provider in the past year. We conducted five focus groups and eight interviews (N = 30). Semistructured guides queried participants on interpretations of the screening question and preferences for raising reproductive health concerns during a primary care visit. We employed inductive thematic analysis. Results Participants interpreted the question as offering contraception or pregnancy counseling and care, although younger participants also understood it as offering sexual and reproductive health services broadly. Participants also connected the question with discussions about their ability to conceive. Some participants described experiences with provider assumptions and implicit bias. Tensions emerged around accepting primary care as a setting for reproductive health due to a perceived lack of specialized training. Conclusions Participants interpreted the screening question as intended, indicating face validity. Primary care settings should increase patients' awareness of reproductive health service availability, such as by routinely introducing a services-based screening question.
An alternative numerical implementation of the Burnett family of acoustic infinite elements

In a series of pioneering papers, Burnett and Holford presented the formulation and numerical implementation of three-dimensional acoustic infinite elements for modeling acoustic fields in exterior unbounded domains surrounding a structure. They are all based on a multipole expansion outside a closed coordinate surface that circumscribes the structure; the multipole expansion has a radial variable r, and two angular variables that describe the surfaces r=const. In the finite element representation, the pressure field is discretized using a product of radial and angular shape functions. The angular variables are discretized directly using nodal angular values. However, in some cases, and especially in problems involving symmetry, nodes are located in certain positions where one of the angular variables is undefined, thus leading to errors in the value of the angular variable in the interior of the elements connected to these nodes, and hence in the computed acoustic field. To overcome this problem, we propose an alternative numerical formulation in this work, which is based on the interpolation of the position vector expressed in the global Cartesian coordinate system (as in conventional finite elements) instead of the interpolation of angular variables. We present numerical solutions for a few benchmark problems using the proposed method.
Investigation of dynamics of laser-produced carbon plasma during the laser irradiation using collective Thomson scattering

Plasma temperature, density, and flow velocity are the critical physical properties of laser produced plasma (LPP) to reveal the ablation dynamics, energy transport, and hydrodynamic evolution. In the time window during and just after laser irradiation, experimental data are very scarce so that many theoretical models remain untested. Here we report a clear evolution history of LPP expansion dynamics within 0–14 ns after the laser peak and in a region very close to the target (0.13–0.6 mm). A table-top Nd:YAG laser (intensity 6 × 109 W cm−2, pulse 7 ns) was used to generate the LPP from a planar graphite target, whose width was arranged to be smaller than the laser spot diameter to produce a one-dimensional planar expansion plasma near the target. The electron density ( ne ), temperature ( Te ), and drift velocity ( Vd ) in the LPPs were measured using the ion feature of collective Thomson scattering, providing a space- and time-resolved 2D profile of the LPP. The experimental observations made it possible for the expansion dynamics to be compared directly with the LPP expansion models. The results suggest that during the laser pulse, the LPP is approximately isothermal and expands predominantly one-dimensionally in the target normal direction, in which the LPP drift velocity is found to increase linearly with distance. The linear extrapolation of the velocity indicates that the LPP has a considerable velocity at the initial target surface; this velocity is approximately the speed of sound derived from the observed Te . The experimental results were found to be in moderate agreement with the 1D self-similar isothermal expansion model. The ratio of the internal to kinetic energy in the observed area was ∼0.6, as predicted by the isothermal expansion model. The experimental findings were compared with the results of the 2D hybrid code STAR, and good agreement was obtained.