Miracle-dz/UniFAR-FTUs huggingface dataset:
Similarity-based local community detection for bipartite networks

Local community detection aims to obtain the local communities to which target nodes belong, by employing only partial information of the network. As a commonly used network model, bipartite applies naturally when modeling relations between two different classes of objects. There are three problems to be solved in local community detection, such as initial core node selection, expansion approach and community boundary criteria. In this work, a similaritybased local community detection algorithm for bipartite networks (SLCDB) is proposed, and the algorithm can be used to detect local community structure by only using either type of nodes of a bipartite network. Experiments on real data prove that SLCDB algorithms output community structure can achieve a very high modularity which outperforms most existing local community detection methods for bipartite networks.
Breast cancer in Kumasi, Ghana.

BACKGROUND Breast cancer is the leading cause of cancer deaths in Ghanaian women. OBJECTIVE To describes the characteristics of breast cancer patients attending the Komfo Anokye Teaching Hospital in Kumasi, Ghana. METHOD The study was conducted at the Komfo Anokye Teaching Hospital. Between July 1st 2004 and June 30(th) 2009 patients presenting with breast lumps were assessed by clinical examination, imaging studies and pathological examination. Relevant clinical and pathological were recorded prospectively data on all patients with microscopically proven breast cancer. The cancers were graded according to the modified Bloom-Richardson system. Tissue immunoperoxidase stains for oestrogen, progesterone receptors and c-erb2 oncogene were performed with commercially prepared antigens and reagents. RESULTS Nineteen thousand four hundred and twenty-three (19,423) patients were seen during the study period. There were 330 (1.7%) patients with histologically proven breast cancer. The mean age was 49.1 years. A palpable breast lump was detected in 248 patients (75.2%). Two hundred and eighty-one patients (85.2%) presented with Stages III and IV, 271 (82.1%) invasive and 230 (85.2%) high grade carcinomas. Oestrogen and progesterone receptors were positive in 32 and 9 cases respectively. Her2 protein was positive in 11 cases. CONCLUSION In Kumasi, as in other parts of Ghana, breast cancer affects mostly young pre-menopausal who present with advanced disease. The cancers have unfavourable prognostic features and are unlikely to respond to hormonal therapy.
: SRSF2 is required for mRNA splicing and spermatogenesis

52 RNA splicing plays significant roles in fundamental biological activities. 53 However, our knowledge about the roles of alternative splicing and underlying 54 mechanisms during spermatogenesis is limited. Here, we report that 55 Serine/arginine-rich splicing factor 2 (SRSF2), also known as SC35, plays 56 critical roles in alternative splicing and male reproduction. Male germ 57 cell-specific deletion of Srsf2 by Stra8-Cre caused complete infertility and 58 defective spermatogenesis. Further analyses revealed that deletion of Srsf2 59 disrupted differentiation and meiosis initiation of spermatogonia. 60 Mechanistically, by combining RNA-seq data with LACE-seq data, we showed 61 that SRSF2 regulatory networks play critical roles in several major events 62 including reproductive development, spermatogenesis, meiotic cell cycle, 63 synapse organization, DNA recombination, chromosome segregation, and 64 male sex differentiation. Furthermore, SRSF2 affected expression and 65 alternative splicing of Stra8 , Stag3 and Atr encoding critical factors for 66 spermatogenesis in a direct manner. Taken together, our results demonstrate 67 that SRSF2 has important functions in spermatogenesis and male fertility by 68 regulating alternative splicing. 69 map the sites of these single-nucleotide To a comprehensive of mechanisms of SRSF2 depletion in male germ cells, we isolated testes from wildtype mouse at P10 and systematically profiled binding landscape of SRSF2 proteins by using LACE-seq. The results showed that SRSF2 proteins could bind numerous genes in a direct manner. Then, our analysis showed that 321 these SRSF2-binding genes were closely involved in the regulation of RNA splicing, reproductive development, male sex differentiation, regulation of 323 synapse organization, and regulation of chromosome segregation. In addition, 324 RNA-seq analysis further showed that transcriptome and splicing of transcripts in SRSF2-null testes. By combining RNA-seq and LACE-seq data, we identified 262 downregulated, and 187 upregulated transcripts as direct targets of SRSF2 in testes. The two omics data reflected that deletion of SRSF2 directly the of critical genes ,
Efficient Algorithms and Architectures for Multiuser Channel Estimation and Detection in Wireless Base-station Receivers

This paperpresentsefficient algorithmsandarchitecturedesignsthatcanmeetreal-timerequirementsof multiuserchannelestimationanddetectionin futurewirelessbase-stationrecei vers.Sophisticatedalgorithmsproposedto implementmultiuserchannelestimationanddetectionmake their real-timeimplementationdifficult oncurrentDigital SignalProcessor (DSP)-basedrecei vers. A maximum-likelihoodbasedmultiuserchannelestimationschemerequiringmatrix inversionsis redesignedfrom an implementationperspecti ve for a reducedcomplexity, iterative schemewith a simplefixed-pointVLSI architecture.A reduced-comple xity, bit-streamingmultiuserdetection algorithmthat avoids the needfor multishotdetectionis alsodevelopedfor a simple,pipelined VLSI architecture.Thus, we show that real-timesolutions,with 3-4 ordersof magnitudeperformanceimprovementsover DSPs,canbeachievedfor next generationwirelesssystemsby (1) designingthealgorithmsfrom animplementationperspecti ve,withoutsignificantlossin errorrate performance, (2) taskpartitioningand(3) designingbit-streamingfixed-pointVLSI architectures to exploit availablepipelining,parallelismandbit-level computations.
A multi-scale investigation of movement patterns among black-tailed prairie dog colonies

Dispersal remains one of the most important, yet least understood, life history traits. As the vehicle of gene flow among populations, dispersal can both relieve inbreeding depression and prevent local adaptation. Regionally, dispersal can stabilize or destabilize metapopulations, given its critical roles in disease transmission among populations as well as recolonization following local extinction events. Furthermore, in light of climate change and increasing habitat loss and fragmentation, the ability to navigate through unfamiliar, unsuitable habitat between populations is essential to the long-term survival of a species across its range. In my dissertation, I present a multi-scale investigation of factors affecting gene flow and disease transmission among populations of a keystone species and an agricultural pest of the North American prairie: the blacktailed prairie dog (Cynomys ludovicianus). Black-tailed prairie dogs are social, grounddwelling squirrels that live in spatially isolated populations called colonies. First, we conducted a landscape genetic analysis of black-tailed prairie dogs throughout a large portion of their current range. Our estimates of gene flow indicate that the genetic neighborhood size of both male and female prairie dogs reaches 40-60 km within shortgrass prairie, whereas colonies within mixed-grass prairie are more isolated. At a broad scale, we observed isolation-by-distance among colonies and great influence of grassland productivity on genetic connectivity; however, neither distance nor landscape characteristics greatly explained observed genetic differentiation among colonies separated by < 50 km. Last, we investigated whether landscape features could predict disease transmission patterns of sylvatic plague among colonies in short-grass prairie and found evidence that pastures act as corridors for plague transmission. Our results indicate that black-tailed prairie dogs are more resilient to habitat loss and fragmentation than other obligate grassland species and likely capable of transmitting sylvatic plague over long distances. Taken together, these studies illustrate how a multi-scale approach can reveal complexities of dispersal dynamics that would otherwise remain undetected. A MULTI-SCALE INVESTIGATION OF MOVEMENT PATTERNS AMONG BLACK-TAILED PRAIRIE DOG COLONIES
We the Billion: A Social Psychological Perspective on India′s Population

Introduction Introduction Population Explosion: The Neglected Malaise in India The Futile Long March Government and Political Approach Two Perspectives Socio-Cultural vs. Empirical 'Representations Sociale' A Composite Approach The Holy Trinity 'Thinking Minorities' Common Sense and Communication Uttar Pradesh The Fertile Womb of India Exhume the Killing Fields Being Pragmatic and Successful
Analysis of the physical layer security enhancing of wireless communication system under the random mobile

User mobility is a major feature of wireless networks. At present, physical layer security research rarely considers the impact of user mobility on the physical layer security performance in the network. In this study, the authors propose a random mobile user physical layer security model and study the impact of random waypoint movement users on the security performance of the physical layer in wireless networks, in which an artificial noise security scheme under the multi-antenna transmission model is considered. They derive the closed expression of positive secrecy capacity probability and secrecy outage probability under this model. The results prove that system security is enhanced because of the users’ mobility.
Through a

Effects of inelastic electron – phonon interactions and different contact geometries on the electron transport and thermoelectric properties of the C 60 molecule are studied by Green ’ s function theory within the framework of polaron transformation. It is seen that the current ( I e ) and energy flux ( I Q ) values with respect to the contact types are ordered as I e / q ( C 1 )< I e / q ( C 6 )< I e / q ( C 5 ). The results reveal that the thermopower – energy curves have strictly monotonic character which show the staircase structures. Their stair numbers depend on contact types and presence of electron – phonon interactions. It is shown that the oscillatory behavior of thermal conductance is dramatically dependent on contact types and e – p interactions. Also, the values of the dimensionless figures of merit ( ZT 0 ) lie in the interval [0.322 ×10 − 7 , 0.194 ×10 − 3 ], and effect of contact types is small on the values of ZT 0 s.
Collateral Damage? On Collateral, Corporate Financing and Performance

In this paper, we investigate the economy-wide effects of the collateral channel by exploiting: (i) a legal reform in Sweden in 2004 that reduced collateral values, and (ii) a dataset that covers all incorporated firms in Sweden over the period 2000-2006. We find that the loss in collateral value reduces both the amount and the maturity of firm debt and leads firms to contract investment, employment, and assets. The legal reform may distort investment and asset allocation decisions, as firms that reduce their holdings of assets with low collaterizable value and firms that hold more liquid assets consequently become less productive and innovative. Our results therefore document the potency of a collateral channel outside of a crisis.
Simulation of Spectra Code (SOS) for ITER Active Beam Spectroscopy

The concept and structure of the Simulation of Spectra (SOS) code is described starting with an introduction to the physics background of the project and the development of a simulation tool enabling the modeling of charge-exchange recombination spectroscopy (CXRS) and associated passive background spectra observed in hot fusion plasmas. The generic structure of the code implies its general applicability to any fusion device, the development is indeed based on over two decades of spectroscopic observations and validation of derived plasma data. Four main types of active spectra are addressed in SOS. The first type represents thermal low-Z impurity ions and the associated spectral background. The second type of spectra represent slowing-down high energy ions created from either thermo-nuclear fusion reactions or ions from injected high energy neutral beams. Two other modules are dedicated to CXRS spectra representing bulk plasma ions (H+, D+, or T+) and beam emission spectroscopy (BES) or Motional Stark Effect (MSE) spectrum appearing in the same spectral range. The main part of the paper describes the physics background for the underlying emission processes: active and passive CXRS emission, continuum radiation, edge line emission, halo and plume effect, or finally the charge exchange (CX) cross-section effects on line shapes. The description is summarized by modeling the fast ions emissions, e.g., either of the α particles of the fusion reaction or of the beam ions itself.
Explorer Factors that Influence Mammography Screening Behaviour

Aim: To identify the factors that influence mammography screening behaviour in a sample of Greek women. Methods/Sample: Data were collected in Athens-Greece, from individuals who were members of six women’s associations. A subset of 33 women were interviewed about their screening behaviour and experiences out of the 186 women who completed an initial questionnaire. This paper focuses on the findings revealed from the interviews. Women’s associations were approached for the recruitment of the interviewees. Results: Influences arising from women’s immediate networks, such as family and close friends, appeared to be of essential importance in relation to their screening behaviour, while influences from their broader networks were of moderate impact. Fear acted as a motivator but also as a barrier in relation to mammography screening participation. Experiences that arose from engagement with the mammography screening processes were mostly characterized by having to overcome a variety of obstacles, such as long bureaucratic procedures and distrust in doctors. Conclusions: The interpersonal relationships between women and their social networks appeared to have an important and influential role in relation to breast screening behaviour. The quality of these relationships appeared to determine women’s participation in mammography screening. It would appear that future practice needs to focus on these relationships in order to utilize them in a positive way. Future research is needed to explore this further. 2
Which subgroup of patients with rheumatoid arthritis benefits from switching to rituximab versus alternative anti-tumour necrosis factor ( TNF ) agents after previous failure of an anti-TNF agent ?

1 Division of Rheumatology, University Hospital of Geneva, Geneva, Switzerland; 2 Department of Rheumatology, University Hospital of Zurich, Zurich, Switzerland; 3 Department of Rheumatology, Clinical Immunology and Allergy, University Hospital of Bern, Bern, Switzerland; 4 Division of Rheumatology, University Hospital of Basel, Basel, Switzerland; 5 Division of Clinical Epidemiology, University Hospital of Geneva, Geneva, Switzerland; 6 Division of Rheumatology, University Hospital of Lausanne, Lausanne, Switzerland
Two-level Promotion and Ordering Policy in a Supply Chain

This research develops two models to consider retailer sales promotion and manufacturer trade promotion under demand uncertainty. The objective of the first model is to determine the retailer’s optimal promotional effort and order quantity while maximizing the retailer’s profit under exogenous trade promotion. The second model extends the first to consider the manufacturer’s endogenous trade promotion decisions. For these models, three different trade promotion policies (off-invoice, scan-back, unsold-discount) have been compared to identify the policy that can increase the manufacturer’s and the retailer’s profits. For the model with exogenous trade promotion, the retailer’s promotional effort level, order quantity, and profit are highest under the off-invoice trade promotion policy. With respect to the manufacturer’s endogenous trade promotion decisions, the retailer’s promotional effort level, order quantity, and profit, and the manufacturer’s profit are higher under the off-invoice policy than under the scan-backs policy. When comparing the three different trade promotion policies, we also find that the wholesale price is a key factor that influences a manufacturer’s profit. Our research sheds light on the importance of trade promotion policy in supply chain management.
Succeeding in process standardization: Explaining the fit with international management strategy

Purpose The purpose of this paper is to explore the fit between process standardization and international management strategy of multinational corporations (MNCs) by assessing the compatibility between process standardization and corporate structural characteristics in terms of asset configuration and headquarters-subsidiary relationships. Design/methodology/approach First, after a literature review on MNCs’ strategy and process standardization, the study suggests two propositions on the fit between corporate international management strategy and process standardization. Second, to empirically examine the propositions, the study investigates the outcome of process standardization in three cases with different strategic and structural contexts. Third, using the propositions and empirical findings, the study proposes a framework for aligning process standardization with MNCs’ structural characteristics. Findings Process standardization has a higher degree of fit in MNCs pursuing global integration where process standardization parallels the need for coordinating interdependencies in the functional structure, and is consistent with the headquarters’ operational control over the subsidiaries. Process standardization has a lower degree of fit in MNCs seeking local responsiveness as process standardization disturbs the financial control relationship between the headquarters and subsidiaries and is less crucial for coordination as the subsidiaries contain the necessary coordination mechanisms. Originality/value The study provides in-depth understanding of how the international management strategy and consequent structural characteristics of MNCs affects process standardization in the course of a global enterprise resource planning implementation. The study proposes conditions of fit for aligning process standardization with asset configuration and headquarters-subsidiary relationships of an MNC.
Can Multitasking Influence Professional Skepticism?

Motivated by concerns about the adverse effects of multitasking in audit practice and research that highlights the effects of mindset orientation on professional skepticism, we investigate how the performance of tasks consistent with different mindset orientations affects auditors’ professional skepticism in a subsequent, unrelated task. Results show that auditors who first complete a task that requires concrete thinking display greater professional skepticism during a subsequent, unrelated task that involves evaluating a narrow and complete set of evidence [a broad and incomplete set of evidence]. We discuss the implications for professional skepticism in multitasking environments.
Télédétection des surfaces continantales : correction des signatures directionnelles et suivi phénologique

La composante terrestre du cycle du carbone est caracterisee par une grande disparite geographique et une forte variabilite interannuelle. Il est important de suivre et egalement d’essayer de predire l’evolution de ce puits en reponse au changement climatique et aux activites humaines. La connaissance de la physique de la mesure satellitaire nous permet de modeliser les effets directionnels de la surface terrestre et de corriger la mesure de ces effets. Nous creons ainsi des series temporelles d’indice de vegetation peu bruitees sur environ trois decades et nous en extrayons des informations sur la phenologie, qui est l’etude des phases cles du cycle annuel vegetal en relation avec le climat. Ces donnees satellitaires peuvent egalement etre exploitees par les modeles globaux de vegetation, pour : la validation de l’indice de surface foliaire pronostique ; l’assimilation qui permet l’amelioration des bilans des flux de carbone ; la calibration des modeles phenologiques.
Establishing Minimal Clinically Important Differences for the Quality of Life Instrument in Patients with Esophageal Cancer QLICP-ES (V2.0) Based on Anchor-Based and Distribution-Based Methods

Background: The minimal clinically important difference (MCID) is an important phrase with big appeal in a field strug­gling to interpret quality of life (QOL) and other patient-reported outcomes (PRO), is also a bridge between statistics and clinical medicine. This paper is aimed to determine the MCID of esophageal cancer scale among Quality of Life Instruments system for Cancer Patients, QLICP-ES (V2.0). Methods: According to the scoring rule of QLICP-ES (V2.0), the scores of each domain and the overall of the scale were calculated. The MCID values of this scale were established by anchor-based and distribution-based methods. Two criteria A (improves one level after treatments) and B (at least improves one levels after treatments) were defined treatments effects in anchor-based methods, while methods of ES, SEM and RCI were used in distribution-based methods. Results: Using the anchor-based method, according to standard A, the MCID values of physical domain, psychological domain, social domain, common symptom and side-effects domain, the specific domain and the overall were 15.1, 4.4, 3.1, 6.7, 8.5 and 6.0 respectively. According to standard B, the MCID values of above domains and the overall were 19.3, 4.2, 4.8, 7.7, 9.5 and 7.5 respectively. Under the distribution-based methods, the MCID values above calculated by each method (ES, SEM and RCI) are in different ranges from 1.1 to 13.3. Conclusion: All methods have its own advantages and disadvantages to develop the MCID values, so it is necessary to develop the MCID values of QLICP-ES (V2.0) comprehensively with a variety of methods considering the actual situation.
Une illustration des difficultés de l'harmonisation internationale: la comptabilisation des marques en France, en Allemagne et selon les règles de l'IASC

It is often stressed that the process of IASC standard setting and its output are very much influenced by the Anglo-American accounting approach. This is considered to be one of the major reasons for the obvious reluctance of countries to adopt the international accounting standards. The importance given to the two accounting characteristics of " reliability " and " relevance " and their mutual relationship is one of the dominant reasons for the differences between the Continental- European and the Anglo-American accounting philosophy. An area where this competing relationship between relevance and reliability becomes highly obvious is in accounting for intangible assets, and namely for brands. It is then highly interesting to study whether the treatment developed by the IASC differs from the accounting practice in Continental European countries and to consider if it could be adopted easily by enterprises in those countries. That is the main objective of this article, which compares the positions adopted in IAS 38 concerning brands and the related practices in France and Germany. Despite the existence of numerous points of convergence, the article shows some major differences between two countries supposed to follow relatively similar rules. It tends then to draw our attention on the difficulty of international harmonization.