Miracle-dz/UniFAR-FTUs huggingface dataset:
APROVECHAMIENTO DEL BORREGO CIMARRÓN (Ovis canadensis mexicana) EN UNIDADES DE MANEJO DEL NORESTE DE MÉXICO

Se evaluo la sustentabilidad ecologica de la caceria selectiva del borrego cimarron ( Ovis canadienses mexicana ) en las Unidades de Manejo para la Conservacion de la Vida Silvestre (UMA) del estado de Sonora, Mexico; considerando como variable el puntaje de la cornamenta. Se utilizaron animales cazados bajo los esquemas de manejo extensivo e intensivo. Los datos se analizaron mediante regresion lineal, prueba t de student de una cola, analisis de cluster de dos tiempos y un sistema de clasificacion por medio de algoritmo k-means. Aunque la prueba de t no mostro diferencias (p > 0.05), los resultados indican, que en la prediccion de cacerias, las UMA intensivas registraron tendencias superiores (+4.253 puntos en la cornamenta). En los esquemas de manejo, el analisis cluster indica que el agrupamiento 1 clasificado como UMA calidad 10 fue el mas sobresaliente, el cual agrupo a la UMA Isla Tiburon de manejo intensivo. En contraparte, el agrupamiento 10 clasificado como UMA calidad 1, incluyo los borregos Cimarron peor dotados, teniendo siete representantes; seis de ellas extensivas (Big Horn Safari, El Cimarron, Hueverachi, Sierra del Viejo, Los Mochos, Punta de Sirios) y solo una de manejo intensivo (El Sacrificio). El analisis de clasificacion de cornamentas expuso que los borregos cimarron cazados en Sonora, pueden alcanzar puntajes de 180.0742 ± 5.91.
Metabolomics reveals the mechanism of action of meropenem and amikacin combined in the treatment of Pseudomonas aeruginosa

The treatment of Pseudomonas aeruginosa infection often involves the combined use of β-lactam and aminoglycoside antibiotics. In this study, we employed metabolomic analysis to investigate the mechanism responsible for the synergistic activities of meropenem/amikacin combination therapy against multidrug-resistant P. aeruginosa strains harboring OXA-50 and PAO genes. Antibiotic concentrations for meropenem (2 mg/L) monotherapy, amikacin (16 mg/L) monotherapy, and meropenem/amikacin (2/16 mg/L) combination therapy were selected based on clinical breakpoint considerations. Metabolomic analysis revealed significant alterations in relevant metabolites involved in bacterial cell membrane and cell wall synthesis within 15 min of combined drug administration. These alterations encompassed various metabolic pathways, including fatty acid metabolism, peptidoglycan synthesis, and lipopolysaccharide metabolism. Furthermore, at 1 h and 4 h, the combination therapy exhibited significant interference with amino acid metabolism, nucleotide metabolism, and central carbon metabolism pathways, including the tricarboxylic acid cycle and pentose phosphate pathway. In contrast, the substances affected by single drug administration at 1 h and 4 h demonstrated a noticeable reduction. Meropenem/amikacin combination resulted in notable perturbations of metabolic pathways essential for survival of P. aeruginosa, whereas monotherapies had comparatively diminished impacts.
An Exploratory Analysis of Market Orientation of Small and Medium-Sized Businesses (SMEs) in Peru

espanolEl conocimiento tradicional del marketing sostiene que una empresa orientada al mercado proporciona a sus empleados una mejor comprension de sus clientes, competidores y ambiente. La consecuencia de disponer de este conocimiento permite a las organizaciones proveer mayor satisfaccion al cliente y un mejor desempeno para la empresa. El objetivo de este estudio fue evaluar las orientaciones de mercado de los gerentes de pequenas empresas en el ambiente del retail en Peru y proveer informacion empirica acerca de las caracteristicas de los gerentes orientados al mercado y de los gerentes no orientados al mercado. Se realizo un esfuerzo para determinar las diferencias en la importancia percibida de diferentes elementos de la funcion de marketing. EnglishTraditional marketing knowledge says that a market oriented firm provides its employees with a better understanding of its customers, competitors, and environment. The consequence of having this knowledge leads the organization to provide enhanced customer satisfaction and firm performance. The objective of this research was to assess the market orientations of small business managers in the retail environment in Peru and provide empirical information about characteristics of the market oriented managers and non-market oriented managers. A concerted effort was made to determine the differences in the perceived importance of different elements of the marketing function.
The role of high Mg calcite in the preservation of micrite envelopes and textural features of aragonite sediments

Algal borings are responsible for the development of micrite envelopes, and high Mg calcite may be present in these borings and other void spaces within aragonite grains. In these cases, the presence of the two minerals furnishes the solubility contrast necessary for the preservation of textural features in the face of massive solution. The earliest and most rapid change in the diagenesis of such a carbonate sediment is the stabilization of high Mg calcite as low Mg calcite. Simultaneously or later, aragonite may undergo solution, leaving behind a fine network of the less soluble low Mg calcite which is pseudomorphic after high Mg calcite. This network is essentially a skeleton of the original texture of the sediment and serves as a mold and nucleation site for later infilling by calcite.
IR-98-101 / December Shaken not stirred : On Permanence in Ecological Communities

I n t e r n a t io na l I n s t i tu te f o r A p p l i e d S y s t e m s A n a l y s is • A-2 3 6 1 L a x e n b u rg • A u s t r i a Interim Reports on work of the International Institute for Applied Systems Analysis receive only limited review. Views or opinions expressed herein do not necessarily represent those of the Institute, its National Member Organizations, or other organizations supporting the work.
Turbulent Characteristics of the Surface Layer in Rongbuk Valley on the Northern Slope of Mt. Qomolangma

Field campaigns were carried out in June 2007 in Rongbuk valley on north side of Mount Qomolangma over Tibetan Plateau.The turbulent data have been measured at 2 m and 8 m above ground,together with temperature,humidity measurements.The variations of turbulent statistics parameters,differences of wind speed and temperature between 2 m and 8 m have been investigated.Both spectrum and co-spectrum appear to follow Monin-Obukov similarity and Kolmogorov′s prediction for the inertial subrange.The standard deviations of temperature and humility fluctuation support Monin-Obukov similarity theory.In neutral condition,relations between non-dimensional wind speed components and z/L follow \! 1/3 power law\",and σu/u*=3.102,σv/u*=2.931,σw/u*=1.052. The coefficients are different from those in other places in Tibetan Plateau due to its special terrains.Unusual phenomena,such as that the latent heat flux measured at 2 m was always lower that that measured at 8 m in the valley,have been found in all day during the observation period.
Unnatural Selection: Choosing Boys over Girls, and the Consequences of a World Full of Men

Finalist for the Pulitzer Prize A Slate Best Book of 2011 A Discover Magazine Best Book of 2011 Lianyungang, a booming port city, has China's most extreme gender ratio for children under four: 163 boys for every 100 girls. These numbers don't seem terribly grim, but in ten years, the skewed sex ratio will pose a colossal challenge. By the time those children reach adulthood, their generation will have twenty-four million more men than women. The prognosis for China's neighbors is no less bleak: Asia now has 163 million females "missing" from its population. Gender imbalance reaches far beyond Asia, affecting Georgia, Eastern Europe, and cities in the U.S. where there are significant immigrant populations. The world, therefore, is becoming increasingly male, and this mismatch is likely to create profound social upheaval. Historically, eras in which there have been an excess of men have produced periods of violent conflict and instability. Mara Hvistendahl has written a stunning, impeccably-researched book that does not flinch from examining not only the consequences of the misbegotten policies of sex selection but Western complicity with them.
State-of-the-Art of High Power Gyro-Devices and Free Electron Masers. Update 2016 (KIT Scientific Reports ; 7735)

This report reviews the current experimental state-of-the-art of megawatt-class gyrotrons for fusion plasma heating. In addition, it summarizes the status of frequency-tunable gyrotrons, multi-megawatt gyrotrons with coaxial resonator, gyrotrons for technological and spectroscopic applications, relativistic gyrotrons, cyclotron-autoresonance-masers, gyroklystrons, gyro-TWT-and gyrotwystron-amplifiers, gyro-BWOs, gyro-harmonic-convertors gyro-peniotrons, magnicons, and free-electron-masers.
Effects of water inclusion in microclimate modification systems for warm and cool season vegetable crops on temperature and yield.

Four microclimate modifi cation methods including spun-bonded and slitted low tunnels both with and without the addition of waterfi lled plastic tubes were tested for their effect on early and total yields of warm and cool season vegetable crops in Morgantown, West Virginia, USA. Peppers, tomatoes, radishes, and lettuce were organically grown in 2006 and 2007. Early season pepper yields were higher when water tubes were included with low tunnels while early tomato yields did not differ. Total yields for warm season crops in some microclimate modifi cation treatments were higher than the control, and harvests started up to four weeks earlier in the spring. Cool season crop yields in the four treatments showed no increase over the control despite one to three weeks earlier harvests for radish and lettuce. These results show potential for earlier safe planting dates and increased yield, especially in warm season vegetable crops using low tunnels and water tubes. Additionally, economic analysis demonstrated a potential for increased profi ts over control plots using these microclimate modifi cation techniques.
Where Have We Been, Where Are We Going? Taking Stock in Creativity Research

The dedicated work of numerous scholars has, over the last 10 years, led to some radical advances in our understanding of the nature and implications of creativity. This work has been summarized in 2 recent handbooks-Mark Runco's Creativity Research Handbook and Robert Sternberg's Handbook of Creativity. In this article I use these handbooks as a starting point to take stock in both what has been accomplished and what still needs to be done in our attempts to understand creativity. I begin by noting that both handbooks clearly describe the major approaches being used in studies of creativity and the findings resulting from each approach. A careful review of the chapters presented in these handbooks, however, brings to the fore a number of issues. For example, we need critical comparative tests contrasting the merits of different methods and theories, elaboration and extension of our traditional samples and our traditional measures, and more attempts to develop integrative models. However, some topics, such as the demands of practical innovation, cross-field differences in the nature of creative thought, and the effects of creativity on people and social systems need more thorough treatment. By laying a foundation for cumulative research along those lines, publication of these handbooks represents an important step toward development of a coherent, scientific model of the creative act.
Klotho-derived peptide 1 inhibits cellular senescence in the fibrotic kidney by restoring Klotho expression via posttranscriptional regulation

Background: Klotho deficiency is a common feature of premature aging and chronic kidney disease (CKD). As such, restoring Klotho expression could be a logic strategy for protecting against various nephropathies. In this study, we demonstrate that KP1, a Klotho-derived peptide, inhibits cellular senescence by restoring endogenous Klotho expression. Methods: The effects of KP1 on cellular senescence and Klotho expression were assessed in mouse models of CKD. RNA-sequencing was employed to identify the microRNA involved in regulating Klotho by KP1. Gain- or loss-of-function approaches were used to assess the role of miR-223-3p and IncRNA-TUG1 in regulating Klotho and cellular senescence. Results: KP1 inhibited senescence markers p21, p16 and γ-H2AX in tubular epithelial cells of diseased kidneys, which was associated with its restoration of Klotho expression at the posttranscriptional level. Profiling of kidney microRNAs by RNA sequencing identified miR-223-3p that bound to Klotho mRNA and inhibited its protein expression. Overexpression of miR-223-3p inhibited Klotho and induced p21, p16 and γ-H2AX, which were negated by KP1. Conversely, inhibition of miR-223-3p restored Klotho expression, inhibited cellular senescence. Furthermore, miR-223-3p interacted with lncRNA-TUG1 and inhibited its expression. Knockdown of lncRNA-TUG1 increased miR-223-3p, aggravated Klotho loss and worsened cellular senescence, whereas KP1 mitigated all these changes. Conclusion: These studies demonstrate that KP1 inhibits cellular senescence and induces Klotho expression via posttranscriptional regulation mediated by miR-223-3p and lncRNA-TUG1. By restoring endogenous Klotho, KP1 elicits a broad spectrum of protective actions and could serve as a promising therapeutic agent for fibrotic kidney disorders.
Thesis Proposal

In the last decades the number of available ontologies has grown considerably. These resources offer the promise of easily-accessible, open-domain ontological information, but the existence of such diverse ontologies raises the issue of information merging and reuse. A comparison of available ontologies reveals both redundant and complementary coverage, but the variety of frameworks and languages used for ontology development makes it a challenge to merge query results from different ontologies. This research proposes to address this problem by building an ontological middleware level for only small fragments of ontologies in an on-demand basis by querying multiple ontologies and merging the query results from multiple knowledge base systems. We then follow ontological chains and inferences across ontologies, using partial query results from one ontology to query another. This is a more complex version of cross-data-base joins, where the data schemas are sufficiently compatible. An initial evaluation used the federated ontology search for answer type checking in question answering. The results of the evaluation show that it is possible to obtain results that outperform querying ontologies independently in both precision and recall. Solutions to additional problems in querying multiple ontologies such as concept identification and ontology selection will be provided using string and structural similarity measures. We propose the creation of an evaluation framework using the question and answer sets in the TREC evaluations to account for a wider set of ontological operations. 1. PROBLEM STATEMENT . 1 1.1. MOTIVATION. 1 1.2. MOTIVATING EXAMPLE. 3 1.2.1. Question Answering. 4 1.2.2. Example 1 . 4 1.3. THESIS STATEMENT . 9 1.4. EXPECTED CONTRIBUTIONS . 9 1.5. DOCUMENT STRUCTURE . 10 2. RELATED RESEARCH . 11 2.1. ONTOLOGY SELECTION . 11 2.2. ONTOLOGY MAPPING. 12 2.3. ONTOLOGY EVALUATION. 14 3. METHODOLOGY . 15 3.1. BASIC DEFINITIONS. 15 3.1.1. Ontologies and Graphs. 15 3.1.2. Query . 16 3.1.3. Result . 16 3.2. ONTOLOGICAL SEARCH. 17 3.2.1. Operators. 18 3.2.2. Query . 22 3.2.3. Resource Description and Selection . 24 3.2. 4. Merging . 25 3.2. 5. Scoring Results . 30 3.3. KNOWN ISSUES WITH CURRENT WORK . 31 3.3.1. Identification of the correct concepts and relations in ontologies. 31 3.3.2. Concept and edge similarity between concepts in different ontologies . 32 3.3.3. Chains of indirect inference. 32 3.3. 4. Insensitivity in Boosting graphs of different structural properties . 32 4. PRELIMINARY RESULTS . 33 4.1.1. Type Checking . 33 4.1.2. Experimental Setup. 33 4.1.3. Results and Analysis . 34 5. ROADMAP. 36 5.1. THESIS SCOPE . 36 5.2. RESEARCH ACTIVITIES . 37 5.2.1. Graph Matching . 37 5.2.2. Ontological Metadata. 38 5.2.3. Query and Resource Description. 39 5.2. 4. Resource Selection. 40 5.2. 5. Result Merging . 42 5.2. 6. Result Scoring. 42 5.3. EVALUATION. 43 5.3.1. Factoid TREC QA Task . 43 5.3.2. Possible evaluation tasks. 44 5.3.3. Condition of Success. 45 5.4. TIMETABLE . 46 6. REFERENCES. 47
Modélisation et simulation d'écoulements turbulents cavitants avec un modèle de transport de taux de vide

La simulation numerique des ecoulements turbulents cavitants revet de nombreuses difficultes tant dans la modelisation des phenomenes physiques que dans le developpement de methodes numeriques robustes. En effet de tels ecoulements sont caracterises par un changement de phase associe a des gradients de la masse volumique, des variations du nombre de Mach causees par une chute de la vitesse du son, des zones de turbulence diphasique et la presence d'instationnarites.Les travaux de la presente these s'inscrivent dans la continuite des etudes experimentales et numeriques menees au sein du Laboratoire des Ecoulements Geophysiques et Industriels (LEGI),qui visent a ameliorer la comprehension et la modelisation d'ecoulements cavitants. Les simulations s'appuient sur un code compressible associe a une technique de pre-contionnement bas-Mach qui permet de traiter les zones incompressibles. Les ecoulements diphasiques sont reproduits a l'aide d'un modele de melange homogene 1-fluide avec discretisation implicite en pas de temps dual. Enfin la resolution adopte l'approche moyennee RANS qui couple le systeme des equations de conservation avec des modeles de turbulence du premier ordre bases sur la notion de viscosite turbulente.Dans les zones diphasiques, le calcul des variables thermodynamiques necessite l'introduction d'equations d'etat. La pression au sein du melange est ainsi reliee aux grandeurs conservatives soit a partir d'une equation d'etat de melange des gaz raides, soit par une relation sinusoidale incorporant la fraction volumique de vapeur (le taux de vide). La valeur ajoutee de ces travaux de these repose sur l'introduction d'une equation de transport pour le calcul du taux de vide. Celle-ci incorpore un terme source dont le transfert de masse entre les phases est ferme grâce a une hypothese de proportionnalite a la divergence du champ de vitesse. Outre l'amelioration des phenomenes de convection, de dilatation et de collapse, cette equation supplementaire permet de relaxer l'equilibre thermodynamique local et d'introduire un etat metastable pour la phase vapeur.Les simulations 2D et 3D sont realisees sur des geometries de type Venturi caracterisees par le developpement de poches de cavitation partielle instables. L'objectif consiste a reproduire les instationnarites inherentes a chaque profil telles que la formation d'un jet rentrant liquide a proximite de la paroi ou la production de nuages de vapeur convectes par l'ecoulement principal.Les resultats numeriques mettent en avant une variation de la frequence des instationnarites en fonction du calcul de la vitesse du son en zone de melange. D'autre part, la prise en compte de desequilibre de la phase vapeur amplifie les phenomenes de propagation d'ondes de pression generees par le collapse des structures cavitantes et participe a la destabilisation de la poche. Enfin, l'influence de l'equation de transport de taux de vide est analysee en confrontant les resultats des simulations a ceux obtenus ulterieurement a partir d'un modele a seulement trois equations de conservation.
Coupling landscape water storage and supplemental irrigation to increase productivity and improve environmental stewardship in the U.S. Midwest

Agriculture must increase production for a growing population while simultaneously reducing its environmental impacts. These goals need not be in tension with one another. Here we outline a vision for improving both the productivity and environmental performance of agriculture in the U.S. Midwest, also known as the Corn Belt. Mean annual precipitation has increased throughout the region over the past 50 years, consistent with climate models that attribute the increase to a warming troposphere. Stream gauge data indicate that higher precipitation has been matched or exceeded by higher stream flows, contributing to flooding, soil loss, and excessive nutrient flux to the Gulf of Mexico. We propose increasing landscape hydrologic storage through construction of ponds and restoration of wetlands to retain water for supplemental irrigation while also reducing flood risks. Primary productivity is proportional to transpiration, and analysis shows that in the U.S. Midwest both can be sustainably increased with supplemental irrigation. The proposed strategy should reduce interannual yield variability by limiting losses due to transient drought, while facilitating adoption of cropping systems that “perennialize” the landscape to take advantage of the full potential growing season. When implemented in concert, these practices should reduce the riverine nitrogen export that is a primary cause of hypoxia in the Gulf of Mexico. Erosive sediment losses should also be reduced through the combination of enhanced hydrologic storage and increased vegetative cover. Successful implementation would require watershed‐scale coordination among producers and landowners. An obvious mechanism to encourage this is governmental farm policy.
Neogene Caribbean Plate rotation and associated Central American tectonic evolution

During the Neogene the Caribbean plate moved eastward with respect to the North and South American plates. Reconstructing this motion by closing the Cayman Trough along its bounding transform faults creates a gore of ocean between northern Central America and southern Mexico. We present, instead, a reconstruction which juxtaposes these two continental areas by strike slip motion. Using geological evidence from around the Cayman Trough, the strike-slip fault zones of northern Central America, and the continental margin of southern Mexico as our constraints, we propose that seafloor spreading began in the Cayman Trough at 30 ± 5 Ma and that subsequently there was 1100 km of relative plate displacement at an average rate of 3.7 ± 0.6 cm/yr. This Neogene plate motion cannot be achieved by rigid plate rotation about a single pole, which implies that Central America must have rotated anticlockwise relative to the rest of the plate. There is evidence for internal plate deformation in Central America consistent with such a sense of rotation. Our suggestion of an originally easterly trending arc in southern Central America is more consistent with the timing and geometry of the collision of Panama with northern Colombia and the resultant deformation than were earlier models that depicted collision of a northerly trending arc.