Miracle-dz/UniFAR-FTUs huggingface dataset:
Vulnerable Narcissism and Problematic Social Networking Sites Use: Focusing the Lens on Specific Motivations for Social Networking Sites Use

Research highlighted that Problematic Social Networking Sites Use (PSNSU) and vulnerable narcissism are associated. However, the mechanisms underlying this relationship are still unclear. The present study aimed to test the mediating role of motives for social networking sites (SNSs) use between vulnerable narcissism and five symptoms of PSNSU (i.e., preference for online social interactions, mood regulation, cognitive preoccupation, compulsive use, and negative outcomes) in a sole model. Self-report questionnaires were completed by 344 SNSs users in the age range of 18–30 years (76.5% females; mean age = 23.80 years, standard deviation = 2.30 years). Vulnerable narcissism, three motives to use SNSs (coping, conformity, enhancement), and symptoms of PSNSU were assessed. Structural equation modeling was used to test for mediation. The results indicate that both motives with positive (i.e., enhancement) and negative (i.e., coping and conformity) valence partially mediated the association between vulnerable narcissism and different symptoms of PSNSU. We conclude that individuals with vulnerable narcissism may develop PSNSU not only as a compensatory strategy to cope with psychosocial difficulties but also as a result of a gratification-seeking process.
Potential benefits of dihydroartemisinin in suppression of dexamethasone induced osteoporosis, osteoclast formation and RANKL induced signaling pathways in adult female albino rat

Osteoporosis is a musculoskeletal disorder characterized by reduced bone density and increased susceptibility to fractures. Fractures cause a considerable increase in mortality, disability, and morbidity incidence. Artemisia annua is a medicinal plant, used for long time in Asian countries and its active metabolite is Dihydroartemisinin (DHA). It is proven to possess anti-inflammatory and antioxidant effects. The present study is the first to investigate the role of different doses of DHA in treatment of Dexamethasone (Dexa)-induced osteoporosis. Thirty female Wister adult rats were divided into three groups for three months. Control and Dexa groups were both six in number. Dihydroartemisinin treated groups, eighteen in number, received intramuscular injection of Dexamethasone and intraperitoneal injection of DHA, then subdivided in three different groups according to DHA doses (10, 20 and 30 mg/kg body wight). Blood level of Ca, P, calcitonin, alkaline and acid phosphatase, and Tissue MDA, GSH were estimated. Tibiae were stained with H&E, Masson- Goldner, and immunological examination of β catenin and RANKL was done. Then, one-way ANOVA test, followed by Tukey’s post-hoc test, was used in order to compare groups, and P value <0.05 was considered statistically significant. A highest dose of DHA showed normalization of blood parameter and oxidative stress markers. Also, bone histology improvement, reduced RANKL and increased β catenin expression were recorded. Treatment with DHA has significantly improved the oxidative stress, biochemical parameters, and bone histology. Dihydroartemisinin might represent a novel approach for modulation of osteoporosis induced by glucocorticoid.
Effect of Resveratrol Supplementation on Intestinal Oxidative Stress, Immunity and Gut Microbiota in Weaned Piglets Challenged with Deoxynivalenol

(1) Background: Deoxynivalenol (DON) is a general mycotoxin that induces severe intestinal barrier injury in humans and animals. Resveratrol (RES) efficiently exerts anti-inflammatory and antioxidant effects. However, the information regarding RES protecting against DON-induced oxidative stress and intestinal inflammation in piglets is limited. (2) Methods: A total of 64 weaned piglets (Duroc × (Landrace × Yorkshire), 21-d-old, barrow) were randomly allocated to four groups (eight replicate pens per group, each pen containing two piglets) for 28 d. The piglets were fed a control diet (CON) or the CON diet supplemented with 300 mg RES/kg diet (RES group), 3.8 mg DON/kg diet (DON) or both (DON+RES) in a 2 × 2 factorial design. (3) Compared with unsupplemented DON-challenged piglets, RES supplementation in DON-challenged piglets increased ileal villus height and the abundance of ileal SOD1, GCLC and PG1-5 transcripts and Muc2 protein (p < 0.05), while decreasing the mRNA and proteins expression of ileal IL-1β, IL-6 and TNF-α, and malondialdehyde (MDA) levels in plasma and ileum in DON-challenged piglets (p < 0.05). Moreover, the abundances of class Bacilli, order Lactobacillales, family Lactobacillaceae and species Lactobacillus gasseri were increased in DON-challenged piglets fed a RES-supplemented diet compared with those in DON-challenged piglets(p ≤ 0.05). (4) Conclusions: our results indicated that RES supplementation in DON-challenged piglets efficiently attenuated intestinal inflammation and oxidative stress and improved gut microbiota, thereby alleviating DON-induced intestinal barrier injury.
Anterior Cruciate Ligament Reconstruction Using Hamstring Graft in a Patient with Achondroplasia: A Case Report

Background: Achondroplasia is a rare autosomal dominant disorder result-ing in skeletal dysplasia. Any injury to the anterior cruciate ligament among people already suffering from achondroplasia results in devastating effects. In this report, the outcome of the hamstring graft arthroscopic reconstruction technique for anterior cruciate ligament injury in achondroplasia patients is assessed. The patient in the present case report exhibits the potential for excellent outcomes four months post-surgical follow-up on Lysholm Knee Scoring Scale. This encouraging result, ought to persuade surgeons to use the hamstring graft arthroscopic restoration approach in achondroplasia instances like these. Timely and excellent recovery in such complicated surgical cases, would reduce the obstacle to surgery for several patients with achondroplasia. It would also improve the methods of managing these patients with this par-ticular surgical technique.
HT-Net: A Hybrid Transformer Network for Fundus Vessel Segmentation

Doctors usually diagnose a disease by evaluating the pattern of abnormal blood vessels in the fundus. At present, the segmentation of fundus blood vessels based on deep learning has achieved great success, but it still faces the problems of low accuracy and capillary rupture. A good vessel segmentation method can guide the early diagnosis of eye diseases, so we propose a novel hybrid Transformer network (HT-Net) for fundus imaging analysis. HT-Net can improve the vessel segmentation quality by capturing detailed local information and implementing long-range information interactions, and it mainly consists of the following blocks. The feature fusion block (FFB) is embedded in the shallow levels, and FFB enriches the feature space. In addition, the feature refinement block (FRB) is added to the shallow position of the network, which solves the problem of vessel scale change by fusing multi-scale feature information to improve the accuracy of segmentation. Finally, HT-Net’s bottom-level position can capture remote dependencies by combining the Transformer and CNN. We prove the performance of HT-Net on the DRIVE, CHASE_DB1, and STARE datasets. The experiment shows that FFB and FRB can effectively improve the quality of microvessel segmentation by extracting multi-scale information. Embedding efficient self-attention mechanisms in the network can effectively improve the vessel segmentation accuracy. The HT-Net exceeds most existing methods, indicating that it can perform the task of vessel segmentation competently.
The Concept of Sustainability in the Context of the English-speaking Educational Discourse

: The study touches upon the issues of a sustainable education targeted at the balance between nature and civilization as well as society and its individuals. The purpose of this paper is to demonstrate that sustainability has become one of the key concepts in transdisciplinary academic discourse carried out in English, and to examine the language with the help of which the concept of sustainability is approached in recent publications on education. It is hypothesized that today’s reorientation to sustainable education has necessitated the meeting point of educational and ecological discourses to tackle modern umbrella concepts and issues of sustainable development, its challenges, opportunities, and strategies. The findings about communicative means, tools and strategies preferred for verbalization of the sustainable education concept reveal transformations in modern education processes, its participants, design, conditions, and outcomes. The analysis of academic discourse on sustainable education sheds light on the rhetorical repertoire of sustainability, relevance of future strategies in education implemented to converge ecological and professional competence, social awareness and individuals’ experience.
Large-Scale Sequencing of Borreliaceae for the Construction of Pan-Genomic-Based Diagnostics

The acceleration of climate change has been associated with an alarming increase in the prevalence and geographic range of tick-borne diseases (TBD), many of which have severe and long-lasting effects—particularly when treatment is delayed principally due to inadequate diagnostics and lack of physician suspicion. Moreover, there is a paucity of treatment options for many TBDs that are complicated by diagnostic limitations for correctly identifying the offending pathogens. This review will focus on the biology, disease pathology, and detection methodologies used for the Borreliaceae family which includes the Lyme disease agent Borreliella burgdorferi. Previous work revealed that Borreliaceae genomes differ from most bacteria in that they are composed of large numbers of replicons, both linear and circular, with the main chromosome being the linear with telomeric-like termini. While these findings are novel, additional gene-specific analyses of each class of these multiple replicons are needed to better understand their respective roles in metabolism and pathogenesis of these enigmatic spirochetes. Historically, such studies were challenging due to a dearth of both analytic tools and a sufficient number of high-fidelity genomes among the various taxa within this family as a whole to provide for discriminative and functional genomic studies. Recent advances in long-read whole-genome sequencing, comparative genomics, and machine-learning have provided the tools to better understand the fundamental biology and phylogeny of these genomically-complex pathogens while also providing the data for the development of improved diagnostics and therapeutics.
Chronic Stress Is Associated with Reduced Mindful Acceptance Skills but Not with Mindful Attention Monitoring: A Cross-Sectional Study

Mindfulness-based interventions (MBIs) are effective in reducing chronic stress, but their therapeutic mechanisms are unclear. One possibility is that MBIs act by re-training attention monitoring and acceptance skills that have been impaired by chronic stress exposure. However, little research has investigated the association between chronic stress, monitoring, and acceptance. In this cross-sectional study we hypothesised observing correlations between stress, and (impaired) monitoring and acceptance. Moreover, we exploratively compared the magnitude of the correlations between chronic stress and four acceptance measures. Finally, we explored whether the association between stress and monitoring is moderated by acceptance. Eighty-five adults participated in the study and completed self-reported chronic stress and acceptance questionnaires and a mindful attention behavioural task. The results revealed that chronic stress was associated with reduced acceptance (all ps < 0.01) but not with monitoring. Exploratory analyses revealed no differences in the magnitude of the correlations between stress and each acceptance measure, except for the combined facets of mindfulness acceptance subscales and nonreactivity subscale (p = 0.023). Further analyses revealed a significant negative association between stress and the interaction between acceptance and the target detection component of monitoring (p = 0.044). Surprisingly, these results show that stress is associated with reduced monitoring at higher levels of acceptance. Theory-driven intervention studies are warranted to complement our results.
Synthetic Differential Geometry

Preface to the second edition (2005) Preface to the first edition (1981) Part I. The Synthetic Ttheory: 1. Basic structure on the geometric line 2. Differential calculus 3. Taylor formulae - one variable 4. Partial derivatives 5. Taylor formulae - several variables 6. Some important infinitesimal objects 7. Tangent vectors and the tangent bundle 8. Vector fields 9. Lie bracket 10. Directional derivatives 11. Functional analysis - Jacobi identity 12. The comprehensive axiom 13. Order and integration 14. Forms and currents 15. Currents - Stokes' theorem 16. Weil algebras 17. Formal manifolds 18. Differential forms in terms of simplices 19. Open covers 20. Differential forms as quantities 21. Pure geometry Part II. Categorical Logic: 1. Generalized elements 2. Satisfaction (1) 3. Extensions and descriptions 4. Semantics of function objects 5. Axiom 1 revisited 6. Comma categories 7. Dense class of generators 8. Satisfaction (2) 9. Geometric theories Part III. Models: 1. Models for axioms 1, 2, and 3 2. Models for epsilon-stable geometric theories 3. Well-adapted models (1) 4. Well-adapted models (2) 5. The algebraic theory of smooth functions 6. Germ-determined T-infinity-algebras 7. The open cover topology 8. Construction of well-adapted models 9. Manifolds with boundary 10. Field property - germ algebras 11. Order and integration in cahiers topos Appendices Bibliography Index.
Empowering mathematics teachers to meet evolving educational goals: the role of “epistemic objects” in developing actionable practice knowledge in tumultuous times

ABSTRACT In recent decades, the aims and objectives of education – and therefore public discourse on the appropriate skills and attributes of mathematics teachers – have been rapidly shifting due to forces from outside the teaching profession. The forces driving change in mathematics are as diverse as the emergence of “Industry 4.0” and “STEM,” new directions in transnational education policy making, and the COVID-19 pandemic. This paper contributes to a growing literature seeking to empower teachers to respond to the complexity of such multifaceted change expansively rather than defensively. It does so through the refinement and application of practical theories of educational change and approaches to building actionable practice knowledge. Specifically, this paper will argue for the use of the epistemic object as a practical focus for changes to practice chosen by the profession. This argument will be made within the framework of practice architectures offered by Kemmis and others. The paper first considers the impact of some recent disruptions on teaching and then provides a “worked example” of using mathematical proficiencies as an epistemic object able to practically support teachers to develop actionable knowledge grounded in the specifics of their own professional context.
Physical properties of the double exchange and its relevance to the specific heat of double perovskite materials

In response to the experimental discovery of double perovskite Ru- base material, The magnetic and electronic properties of the double exchange mechanism are studied theoretically. The electron band structure and the spin wave spectrum response at zero temperature with the canting background are computed from the first principle Hamiltonian. The long range Coulomb interaction between charge carriers is found to be crucial in stabilizing the canting order. A Monte Carlo simulation is performed on de-Gennes's effective magnetic Hamiltonian with classical spin approximation. The peaks of the specific heat as a function of temperature, which correspond to FM(AF) and canting transitions, and its response to the external magnetic field are consistent with the observation. For certain region of parameters, a more complex canting order than layer type is found at sufficiently low temperature. The effective interaction between carriers via exchanging a magnon wave is found to be rather similar to that via exchanging an acoustic phonon. The pros and cons to a genuine superconducting order in this system is analyzed.
A Miniaturized Triple-Band Antenna Based on Square Split Ring for IoT Applications

This article presents a miniaturized triple-band antenna for Internet of Things (IoT) applications. The miniaturization is achieved by using a split square ring resonator and half ring resonator. The antenna is fabricated on an FR4 substrate with dimensions of (33 × 22 × 1.6) mm3. The proposed antenna resonates at the frequencies 2.4 GHz, 3.7 GHz, and 5.8 GHz for WLAN and WiMax applications. The obtained −10 dB bandwidth for the three bands of the proposed antenna are 300 MHz, 360 MHz, and 900 MHz, respectively. The measured reflection coefficient values of the proposed antenna corresponding to each resonant frequency are equal to −14.772 dB, −20.971 dB, and −28.1755 dB, respectively. The measured gain values are 1.43 dBi, 0.89 dBi, and 1 dBi, respectively, at each resonant frequency. There is a good agreement between the measured and simulated results, and both show an omnidirectional radiation pattern at each of the antenna resonant frequencies that is suitable for IoT portable devices.
Role of Neoadjuvant Chemotherapy in Ovarian Serous Cancer Followed by Debulking

Background: Ovarian cancers are one of the most common gynecological cancers and serous tumor is one of the most common histological form of extrauterine female genital tract tumors. While ovarian serous carcinoma is a well-studied human gynecologic malignancy, this high-grade tumor remains lethal. Case description: A 50-year-old female with P2L2A2 (Para-2, Live-2, Abortion-2) presented with pain in the abdomen for six months. Investigations were done, which revealed bilateral large ovarian cystic lesion suggestive of ovarian malignancy. She underwent six cycles of chemotherapy followed by exploratory laparotomy. Objective: We examined the precipitating factors, laboratory abnormalities including cancer antigen 125 (CA-125) levels, treatment strategies including neoadjuvant therapy and debulking surgery, and clinical recovery in ovarian malignancy. Conclusion: Primary debulking surgery (PDS), although the preferred treatment for ovarian cancer, is accompanied by combination chemotherapy based on platinum. However, neoadjuvant chemotherapy (NACT) followed by interval debulking surgery (IDS) has gained a reputation as a legitimate therapeutic technique specifically for patients with stage IV unresectable bulky tumors or poor general condition. Treatment with NACT is now expected to become a routine treatment or a successful treatment choice for advanced epithelial ovarian cancer (EOC).
Pengaruh Financial Reporting Quality, Debt Maturity, Ceo Career Concerns Terhadap Investment Efficiency

This research aims the effect of financial reporting quality, debt maturity, and CEOcareer concerns on investment efficiency on manufacturing industry listed on the IndonesiaStock Exchange during 2016-2018. Sample was selected using purposive sampling methodand the valid data was104 companies with 259 samples data. Data processing techniquesusing multiple regression analysis with helped by Eviews (Econometrical Views) version 11.The results of this study indicate only financial reporting quality have a significant influenceon investment efficiency, debt maturity and CEO career concerns have not a significantinfluence on investment efficiency. The implication of this study is the need to increasefinancial reporting quality that will increase investment efficiency which will mitigateinformation asymmetry in particular moral hazard and adverse selection.
Metastatic Lung Adenocarcinoma: Unusual Presentation with Focal Neurological Deficit

Patient: Male, 63-year-old Final Diagnosis: Metastatic lung adenocarcinoma Symptoms: Headache • weakness Medication: — Clinical Procedure: Abdomen CT • brain CT • bronchoscopy • chest computed tomography • chest xray • endobronchial ultrasound • fine needle aspiration • MRI brain Specialty: Critical Care Medicine • General and Internal Medicine • Oncology • Radiology Objective: Unknown etiology Background: Sudden focal neurologic deficits have a high index of suspicion of stroke. It is crucial to investigate potential underlying causes of sudden neurological deficit in the Emergency Department (ED) to enhance better recognition and proper care. Case Report: A 63-year-old man presented to the ED with left-sided weakness and headache of a 2-week duration. Ischemic stroke was preliminarily diagnosis in the ED. Brain computed tomography (CT) showed an abnormality in the right parietal lobe. A chest X-ray showed right lung opacity, suggesting a mass in the right upper lobe of the lung. Subsequently, malignancy was suspected. Brain magnetic resonance imaging (MRI) showed lesions in the right temporal and right parietal region. CT scans of the chest, abdomen, and pelvis were ordered to identify the primary source of malignancy. Multiple nodules within the lungs and liver were found; a biopsy was taken from the nodules and sent to the Pathology Laboratory. Final impression made after the results was primary lung adenocarcinoma with brain and liver metastasis. The patient was referred to Palliative Care team by the Oncology team after malignancy workup to get the proper attention. Conclusions: A hypodense area in CT/MRI with unilateral weakness and headache does not necessarily mean that there is an underlying stroke. However, it can represent brain metastasis. In this case report, we aim to increase awareness that hypodensity in the brain could represent brain metastasis, not necessarily simple ischemic stroke. Therefore, further workup should be done to avoid missed diagnoses, as the approach is different.
Nanomaterials as Redox Mediators in Laccase-Based Amperometric Biosensors for Catechol Assay

Laccase is a copper-containing enzyme that does not require hydrogen peroxide as a co-substrate or additional cofactors for an enzymatic reaction. Nanomaterials of various chemical structures are usually applied to the construction of enzyme-based biosensors. Metals, metal oxides, semiconductors, and composite NPs perform various functions in electrochemical transformation schemes as a platform for the enzyme immobilization, a mediator of an electron transfer, and a signal amplifier. We describe here the development of amperometric biosensors (ABSs) based on laccase and redox-active micro/nanoparticles (hereafter—NPs), which were immobilized on a graphite electrode (GE). For this purpose, we isolated a highly purified enzyme from the fungus Trametes zonatus, and then synthesized bi- and trimetallic NPs of noble and transition metals, as well as hexacyanoferrates (HCF) of noble metals; these were layered onto the surfaces of GEs. The electroactivity of many of the NPs immobilized on the GEs was characterized by cyclic voltammetry (CV) experiments. The most effective mediators of electron transfer were selected as the platform for the development of laccase-based ABSs. As a result, a number of catechol-sensitive ABSs were constructed and characterized. The laccase/CuCo/GE was demonstrated to possess the highest sensitivity to catechol (4523 A·M−1·m−2) among the tested ABSs. The proposed ABSs may be promising for the analysis of phenolic derivatives in real samples of drinking water, wastewater, and food products.