Miracle-dz/UniFAR-FTUs huggingface dataset:
Effect Of Educational Program For Hemodialysis Patients Regarding Their Knowledge And Practice About Self Care Behaviour

Chronic kidney diseases affect up to one in ten adults globally, and it is always permanent and progressive. Aim: To determine the effect of educational program regarding self-care behavior for hemodialysis patients at Beni-Suef University Hospital. Subject and methods: A quazi-experimental research design has been used. It was conducted at Beni-Suef University Hospital. 55 patients who attended the dialysis unit at Beni-Suef university hospital were selected to participate in the current study. The first tool: A structured interviewing questionnaire that includes two parts; Part 1: Their socio-demographic characteristics. Part 2: include past history of hemodialysis patients. Part 3: Knowledge assessment data sheet used to assess knowledge about kidney and renal failure. Second tool: Self-care measurement scale was used to measure practice regarding self-care behavior of hemodialysis patients. Results: The mean age of the participants was 32.60 ± 20.88, 90.9% of studied sample had poor scores of knowledge at pretest which improved to good scores at immediate posttest. The total universal self-care practice scores of the studied hemodialysis was 75.82 ± 9.90 at pre-test which improved at post and follow-up tests to (100.27 ± 14.02 and 94.38 ± 11.65) respectively, while the total health deviation self-care practices mean scores of the studied hemodialysis was 59.13 ± 6.01 at pre-test which improved in post and follow-up tests to 83.67 ± 6.27 and 80.95 ± 5.25 respectively. Conclusion: The implemented program about self-care behavior had a good impact on hemodialysis patients' knowledge and practice. Recommendations: Dietary counseling and dietary education programs should be held for hemodialysis patients, which promote hemodialysis patients dietary intakes of appropriate food.
Advances in Modeling Polyglutamine Diseases Using Genome Editing Tools

Polyglutamine (polyQ) diseases, including Huntington’s disease, are a group of late-onset progressive neurological disorders caused by CAG repeat expansions. Although recently, many studies have investigated the pathological features and development of polyQ diseases, many questions remain unanswered. The advancement of new gene-editing technologies, especially the CRISPR-Cas9 technique, has undeniable value for the generation of relevant polyQ models, which substantially support the research process. Here, we review how these tools have been used to correct disease-causing mutations or create isogenic cell lines with different numbers of CAG repeats. We characterize various cellular models such as HEK 293 cells, patient-derived fibroblasts, human embryonic stem cells (hESCs), induced pluripotent stem cells (iPSCs) and animal models generated with the use of genome-editing technology.
A statistically based sentence scoring method using mathematical combination for extractive Hindi text summarization

Abstract Electronic documents contain tremendous amounts of information. A text summary system is needed to save time and rapidly know about the document, because the manual text summary requires time, effort, and costs, which automatically creates a summary from the source document. Hindi is India’s most spoken language. A Hindi document summarization system does not exist. The method of summary generation is either extractive or abstractive. The extractive text summary method extracts the most suitable phrases from input documents to be incorporated into the summary whereas the abstractive is the human-like summary method. To select a summary sentence, it must be the highest score. In this paper, we apply different mathematical combinations using nine textual features to score a sentence. We analyzed the results on 2000 documents taken from the Forum of Information Retrieval Evaluation (FIRE)1 conference using ROUGE evaluation matrices at the retention rate of 40%.
The intellectual structure of behavioral strategy: A bibliometric study

Behavioral strategy is a relatively new subfield of strategic management and yet its roots go back to the origins of the discipline. Its rapid growth over the last few years, the interest created in the research community, and the intrinsically diversified approaches call for organization of the intellectual structure developed by scholars. This paper aims to provide the intellectual structure of the subject based on the published research for the entire period covered by the Social Science Citation Index (SSCI) Database. By using bibliometric and data analytic techniques, we determine the key works in the development of the subfield, the groups that determine the conceptual contributions and the bridging works that provide the common bond between them. To achieve this, we have used co-citation analysis to capture relationships. It is followed by multidimensional scaling (MDS) and a principal component factor analysis (PCFA) for displaying the groups of works that constitute the different lines of research. The study offers useful insights in the discipline and conclusions for future developments in the subject for researchers and practitioners alike.
Newborn and infant hearing screening at primary healthcare clinics in South Africa designated as National Health Insurance pilot sites: An exploratory study

Background Primary healthcare (PHC) is the first point of entry, providing basic services to individuals. South Africa is in the process of re-engineering its PHC as part of National Health Insurance (NHI) plans to ensure universal healthcare coverage. Aim This study aimed to establish whether newborn and infant hearing screening (NIHS) could be integrated into the re-engineering process of the PHC as part of the NHI framework. Setting The NHI pilot clinics in five provinces in South Africa. Methods A non-experimental, descriptive, cross-sectional survey research design was adopted. Questionnaires were sent to nursing managers, unit managers or acting managers at PHC facilities. Nineteen of these self-administered questionnaires were completed. Data were analysed using descriptive statistics. Results Immunisation services were the most common type of service offered at the clinics. Over a quarter of the respondents indicated that NIHS services were offered at their facility in the form of universal NIHS. Equipment was limited with a lack of valid and reliable screening measures. Only 2 (11%) respondents indicated budgetary resources. Follow-up and referral pathways were reported by 10 (53%) respondents, which did not include an audiologist. Conclusions There is a need for careful and systematic planning in terms of early hearing detection programmes at PHC level. Planning needs to commence with considerations of who will perform NIHS, training of these personnel by audiologists and the role of the audiologist within the teams outlined in the NHI Bill.
An Analysis of The Existence Level of West Javanese Traditional Beverages as Sundanese Cultural Heritage

This research focuses on West Javanese traditional beverages. West Javanese traditional beverages are very varied in types. There are two main types of West Javanese traditional beverages in Bandung, namely hot and cold beverages. At present, the existence of traditional beverages is less popular compared to foreign beverages, such as Thai tea, boba milk tea, and so on. A real action in maintaining and preserving these traditional West Javanese beverages is a need. Therefore, this research aims to evaluate the exsistence level or popularity of traditional West Javanese beverages in Bandung, as a contribution to the literature on traditional beverages and a real action in presereving the beverages. This research employs a mix method research, with data collection techniques, using in-depth interviews, questionnaires, literature studies, and documentation studies. The purpose of this study is to determine whether traditional West Javanese beverages still exist in society, considering that in this era of globalization, food trends and people's tastes continue to change from time to time along with the influence of foreign cultures in Indonesia. The results of this study indicate that each type of traditional West Javanese beverages are at different level of existence, and the least exist beverages in society must be increased to avoid extinction.
Hourly Water Demand Forecast Model Based on Bayesian Least Squares Support Vector Machine

As traditional least squares support vector machine (LSSVM)model parameters determined by cross- validation is time-consuming,the Bayesian evidence framework was proposed to infer the LSSVM model parame- ters.The weight vector w and the bias term b of the LSSVM were obtained on the first level of inference.The model hyperparametersμ,ζwere determined on the second level of inference.The model comparison was per- formed on the third level of inference in order to automatically determine the coefficient of kernel function.Ac- cording to the periodicity and trend of water demand series,an hourly water demand forecast model based on Bayesian LSSVM was established.Case analysis shows that the modeling speed of Bayesian LSSVM-based hour- ly water demand forcast model is faster and forcasting precision is higher than those of traditional LSSVM-based model and BP neural network-based model.
Effect of processed quinoa on performance traits, small intestinal morphology, and blood parameters of Ross broiler chickens

Restrictions on access to important components of poultry rations such as corn and soybean meal are among the biggest issues in the poultry feed industry. Quinoa with a very high nutritional value can be a good alternative. The present study aimed to investigate the effect of processed quinoa seeds on performance, small intestinal morphology, and blood parameters of Ross broiler chickens. The present experiment was performed with 5 treatments, 4 replications, and 15 chickens per pen in a completely randomized design. Hydrothermal, extrusion, and expansion methods were used to process quinoa seeds. Apart from the control treatment, 15% of quinoa seeds were included in the other treatments. The studied traits were recorded. The general linear model procedure in SAS software was used to compare the means of treatments. The effect of processing methods on body weight, feed conversion ratio, total protein, uric acid, and blood cholesterol, villi height, crypt villi depth, and length to depth ratio of cryogenic villi of jejunum were significant (P<0.01). Quinoa processing improved its nutritional properties. In general, extrusion and expansion processing methods were more effective than the hydrothermal method in improving the quality of quinoa.
Algorithmic Design in Virtual Reality

Virtual reality has been shown to facilitate perception and navigation inside 3D models, while stimulating creativity and enhancing architect/client interaction. In this scenario, in order to better explore paths along the design space that are suggested from this interaction, it is important to support quick updates to the model while still immersed in it. Algorithmic design, an approach to architectural design that uses parametric algorithms to represent a design space, rather than a single design instance, provides such support. We present a novel architectural design process based on the integration of live coding with virtual reality, promoting an immersive approach to algorithmic design. The proposed workflow entails the use of an algorithmic design tool embedded in a virtual environment, where the architect not only creates the design but also interacts with said design, changing it by live coding its algorithmic representation from within virtual reality. In this paper, we explain the challenges faced and solutions devised for the implementation of the proposed workflow. Moreover, we discuss the applicability of algorithmic design in virtual reality to different stages of the architectural design process and the future developments that may arise from this proposal.
PACER lncRNA regulates COX-2 expression in lung cancer cells

Long noncoding RNAs (lncRNAs) are known to regulate gene expression; however, in many cases, the mechanism of this regulation is unknown. One novel lncRNA relevant to inflammation and arachidonic acid (AA) metabolism is the p50-associated COX-2 extragenic RNA (PACER). We focused our research on the regulation of PACER in lung cancer. While the function of PACER is not entirely understood, PACER is known to play a role in inflammation-associated conditions. Our data suggest that PACER is critically involved in COX-2 transcription and dysregulation in lung cancer cells. Our analysis of The Cancer Genome Atlas (TCGA) expression data revealed that PACER expression is significantly higher in lung adenocarcinomas than normal lung tissues. Additionally, we discovered that elevated PACER expression strongly correlates with COX-2 expression in lung adenocarcinoma patients. Specific siRNA-mediated knockdown of PACER decreases COX-2 expression indicating a direct relationship. Additionally, we show that PACER expression is induced upon treatment with proinflammatory cytokines to mimic inflammation. Treatment with prostaglandin E2 (PGE2) induces both PACER and COX-2 expression, suggesting a PGE2-mediated feedback loop. Inhibition of COX-2 with celecoxib decreased PACER expression, confirming this self-regulatory process. Significant overlap between the COX-2 promotor and the PACER promotor led us to investigate their transcriptional regulatory mechanisms. Treatment with pharmacologic inhibitors of NF-κB or AP-1 showed a modest effect on both PACER and COX-2 expression but did not eliminate expression. These data suggest that the regulation of expression of both PACER and COX-2 is complex and intricately linked.
Incorporação de Parcerias no Planejamento Estratégico da Inovação em uma Estratégia Technology Push de Integração i Partnerships Incorporation in the Innovation Strategic Planning as a Technology Push Integration Strategy

The technology planning methods are one of the solutions to key issues related to innovation process, as the implementation of open innovation strategy and the technology roadmapping, TRM. Some of these methods provide a systematic approach to technology planning, however they have neglected the adoption of partnerships and open innovation. The current work fills this gap including the partnership in technology planning as an important guideline. However, these theories usually do not present procedures or directions about how to identify and plan these partnerships. This paper presents a systematic approach to identify and plan the partnership in technology planning. From a literature review perspective and action research, a specific procedure was developed for the adoption of partners in technology planning, considering different types of partners, as well as the objectives of the partnerships in the innovation process in accordance with the necessary resources: whether for market, technological or financial purposes. The results show that the procedure is useful not only for the organization under study, but also to support distinct innovation planning initiatives.
Cardioprotection of Immature Heart by Simultaneous Activation of PKA and Epac: A Role for the Mitochondrial Permeability Transition Pore

Metabolic and ionic changes during ischaemia predispose the heart to the damaging effects of reperfusion. Such changes and the resulting injury differ between immature and adult hearts. Therefore, cardioprotective strategies for adults must be tested in immature hearts. We have recently shown that the simultaneous activation of protein kinase A (PKA) and exchange protein activated by cAMP (Epac) confers marked cardioprotection in adult hearts. The aim of this study is to investigate the efficacy of this intervention in immature hearts and determine whether the mitochondrial permeability transition pore (MPTP) is involved. Isolated perfused Langendorff hearts from both adult and immature rats were exposed to global ischaemia and reperfusion injury (I/R) following control perfusion or perfusion after an equilibration period with activators of PKA and/or Epac. Functional outcome and reperfusion injury were measured and in parallel, mitochondria were isolated following 5 min of reperfusion to determine whether cardioprotective interventions involved changes in MPTP opening behaviour. Perfusion for 5 min preceding ischaemia of injury-matched adult and immature hearts with 5 µM 8-Br (8-Br-cAMP-AM), an activator of both PKA and Epac, led to significant reduction in post-reperfusion CK release and infarct size. Perfusion with this agent also led to a reduction in MPTP opening propensity in both adult and immature hearts. These data show that immature hearts are innately more resistant to I/R injury than adults, and that this is due to a reduced tendency of MPTP opening following reperfusion. Furthermore, simultaneous stimulation of PKA and Epac causes cardioprotection, which is additive to the innate resistance.
Orchestrating Platform Ecosystems: ARM's Dynamic Capabilities

This article explores the platform strategy of ARM with a particular focus on understanding the company’s dynamic capabilities for managing its ecosystem of partners. ARM’s portfolio of architectural, learning and strategic capabilities are depicted based on data gathered primarily through primary data and supplemented with secondary data. The basic research strategy was to identify those organisational routines that were likely to shape ecosystem-wide innovation.
Postural Stabilization of a Unicycle.

We describe a postural stabilization of a unicycle which has a swinging arm to stabilize rolling motion. The equations of motion for a nonholonomic constraint system are derived, and the equations are linearized and separated into two subsystems which are associated with pitching and rolling motions. The control system is based on the digital optimal theory and the state variables are estimated with finite-time settling observers using the data obtained from the internal sensors. The deviations of the state variables and their estimation errors caused by the sensing errors are evaluated. Experimental results show that the proposed swinging arm system is useful for the postural stabilization of the unicycle, and the finite-time settling observers are effective for estimating the state variables.
Information Requirements for Pilots to Execute 4D Trajectories on the Airport Surface

*† ‡ Trajectory-based operations constitute a key mechanism considered by the Joint Planning and Development Office (JPDO) of the U.S. for managing traffic in high-density or highly complex airspace in the Next-Generation Air Transportation System (NextGen). With this concept applied to surface operations at major airports, current research has been exploring the use of surface 4-dimensional (4 D) trajectories, which use required times of arrival (RTAs) at selected locations along the taxi route. The research has explored the use of collaborative automation systems in the control tower and on the flight deck to plan and execute these 4D trajectories to achieve safe and efficient surface operations, and prototype experimental systems for these automation systems have been developed. This paper reports on a study with human-in-the-loop experiments performed using prototype designs of the flight-deck automation system display to achieve two primary objectives: identify information requirements for the pilot to execute 4D trajectories, and investigate usability of the flight-deck display. More specifically, the findings help to identify the information requirements for the pilots, to discover issues related to the general interface design and properties of the display, and to recommend specific improvements that could be made to the design of the display and how it communicates information to the user.
Perfect I.I.D Processes

This note proves a theorem about i.i. d. i.e. independent and indentically distributed processes, when the index space is a measure space. The statement of the problem corresponding to the theorem proved in this paper appears in [1], in which the concept of a sample distribution limit corresponds to the concept of a perfect i.i. d process in this paper.Theorems proved in this theme, regarding existing and non-existence, have been shown in the economics literature, when the index set is [0; 1], in [2], [3], [4], [5]. The approach taken in thispaper is perhaps, surprisingly elementary. We may apply standard measure extension theorems to show existence. These may be found in [6], [7].
Constructive or Optimized: An Overview of Strategies to Design Networks for Time-Critical Applications

Distributed systems are pervasive nowadays, being found in different areas, from smart toys to smart factories. As the usage of such systems increases, so does their complexity and design. Therefore, this work aims to overview the methods for designing networks that accommodate time-constrained distributed applications. The work starts with a history of time-aware Ethernet-based protocols. Then, it continues with an overview of the design strategies from the literature. For each research paper, there are presented the model, addressed problem, exploration strategy, and results. Furthermore, for each type of problem are identified the constructive and optimization design strategies. Regarding the results, this work investigates the improvements of reliability, timeliness, and network cost.
A hipótese "trabalhador feliz, produtivo": o que pensam os servidores públicos federais The assumption "happy, productive worker": what the federal civil servants think

The assumption “happy, productive worker” claims that happy employees, whose needs are met at their workplaces, show a better performance than unhappy employees. This is a consolidated statement for the business society, but there are very few empirical references. Therefore, this study aims to examine workers’ perception in relation to the assumption “happy, productive worker”. A focus group was conducted, having an exploratory nature, in order to understand how participants see the variables under study. The focus group was conducted in an organization of the
Inflation Dynamics in Pakistan: Forward- looking or Backward-looking?

For a country with a modest open economy like Pakistan, the significance of outlooks in determining inflation dynamic forces is investigated in this paper. For the years 1972 to 2014, the study examines the New Keynesian Phillips Curve (NKPC) in both conventional and hybrid variants. The output gap and labor income are two indicators of economic growth. The Dicky Fuller test are used to check for variable stationary, and the model's long-run parameters were determined using the generalized method of moments. The outcomes of the study demonstrate that the NKPC model appropriately describes inflation dynamics in Pakistan and is data-driven. The production gap was found to be an ineffective proxy for evaluating economic activity, although worker income shares appeared to be highly positive.
Flux Regulation Strategies for Hybrid Excitation Synchronous Machines

This paper investigates methods to achieve a wide constant power speed range (CPSR) in electric drives using hybrid excitation synchronous machines; five strategies are presented and compared. These range from state-of-the-art flux weakening based on demagnetizing armature current injection, to algorithms based on wound excitation (WE) current regulation, all the way to techniques involving both armature and WE current regulation. It is shown that one of these latter strategies allows a theoretically infinite CPSR and unity power factor operation throughout. This result is also verified experimentally, and a 10:1 range is demonstrated. Finally, a discussion is presented on practical limiting issues such as harmonic flux linkage components, inductance variations, and high-speed iron losses.