Miracle-dz/UniFAR-FTUs huggingface dataset:
Human reach envelope and zone differentiation for ergonomic design

In human‐centric design, the human reach envelope is one of the most important components to help layout design for workstations, vehicles, and aircrafts. It also can help people to study the range of motion of different body segments. Various methods have been developed to determine human reach envelopes. This article presents different methods and common challenges. Human reach envelopes only give feedback concerning whether a point is reachable. This is not enough for the designers. The more important information the designers need to know is the zones with different discomfort levels. This capability is a powerful tool for ergonomic designers. In addition, a methodology for workspace solid zone differentiation or surface zone differentiation in the three‐dimensional space is presented. © 2008 Wiley Periodicals, Inc.
Oral Realgar-Indigo Naturalis Formula Treatment for Acute Promyelocytic Leukemia in Children: A Randomized, Control Clinical Trial

Objective To analyze the efficacy, safety, and economy of RIF compared with intravenous arsenic trioxide (ATO) for the induction and consolidation therapy of pediatric APL. Materials and Methods In this randomized control clinical trial (NCT02200978), children with newly diagnosed APL from June 2013 to December 2017 were randomly divided into RIF and ATO groups. The groups were treated with RIF or ATO in combination with all-trans retinoic acid (ARTA) and conventional chemotherapeutic drugs during induction and consolidation therapy. Results Ninteen patients were enrolled, including eight in the RIF group and 11 in the ATO group. After induction therapy, the bone marrow morphologic complete remission (CR) rate, the median time to CR, and molecular remission (promyelocytic leukemia protein (PML)/retinoic acid receptor α (RARα) conversion) rates showed no significant differences between patients in the RIF versus ATO groups (100% vs. 100%, p=1.000; 22 vs. 24 days, p=0.395; 28.5% vs. 54.5%, p=0.367, resp.). After consolidation therapy, the molecular remission rate was 100% in both groups. At the end of more than two years of follow-up, the disease-free survival (DFS) rate was 100% in both groups. Conclusion Oral RIF can achieve similar efficacy to intravenous ATO for APL in children with good safety, less toxicity, fewer side effects, and fewer inpatient days. Therefore, oral RIF can be used as an alternative to intravenous ATO for the treatment of APL in children.
Double-layer suspended stripline resonator with high quality factor for base-station diplexer application

A novel double-layer suspended stripline (DSSL) resonator with high unloaded quality factor is proposed. The DSSL resonator consists of a thin substrate with metal strips on both sides connected by a metallic via hole suspended in the centre of an air-filled cavity, which leads to a much higher unloaded quality factor than the conventional single-layer suspended stripline resonator with an identical resonant frequency. The resonance characteristics of the DSSL resonator are parametric analysed. For demonstration, a compact diplexer for base-station application with channel centre frequencies at 1.95 and 2.14 GHz and absolute bandwidths of 60 MHz is designed, fabricated and measured. The synthesised, simulated and measured results show a good agreement.
UWB Bandpass Filter with Ultra-wide Stopband based on Ring Resonator

Abstract An ultra-wideband (UWB) bandpass filter with ultra-wide stopband based on a rectangular ring resonator is presented. The filter is designed for the operational frequency band from 4.10 GHz to 10.80 GHz with an ultra-wide stopband from 11.23 GHz to 40 GHz. The even and odd equivalent circuits are used to achieve a suitable analysis of the proposed filter performance. To verify the design and analysis, the proposed bandpass filter is simulated using full-wave EM simulator Advanced Design System and fabricated on a 20mil thick Rogers_RO4003 substrate with relative permittivity of 3.38 and a loss tangent of 0.0021. The proposed filter behavior is investigated and simulation results are in good agreement with measurement results.
HUMAN FACIAL EXPRESSIONS RECOGNITION - A SURVEY

-Recognition of human facial expressions is an active research area that finds potential applications in areas such as human-computer interfaces, image retrieval and human emotion analysis. The face is the most extraordinary communicator, capable of accurately signaling emotion in a bore link of a second. Moreover facial expressions convey not only emotions, but other mental activities, social interaction and physiological signals. In this paper we presented the evolution of the analysis of facial expressions and survey some of the published work in this area since 1990 to till date. This paper presents a time-line view of the advances made in this field, the facial parameterization using FACS Action Units (AUs) and MPEG-4 Facial Animation Parameters (FAPs), the applications, and the Databases.
Step-over behavior for Limit Cycle Walkers

In this paper, stepping over a zero height obstacle with minimal actuation is studied for a limit cycle walker modeled as a double inverted pendulum. The obstacle position is estimated by stereo vision. Actuation is realized by a constant torque per step on the hip and a push-off collinear to the trailing leg. Stepping over the obstacle must be accomplished with the obstacle position exactly on a predefined position in between the legs with the final state right after push-off being equal to the initial state. Thus, at least two steps must be taken to perform this task, such that the first step is used to make sure the relative position of the obstacle is correct. In the best case scenario, the obstacle is exactly in between the legs during a nominal walk. In that case, actuation does not have to be adjusted with respect to the nominal actuation. In the worst case scenario the obstacle is exactly at a stepping position. In that case, a translation of the step positions is needed. For stepping over in two steps this is not possible; this is only possible for a small range around the best case scenario. For stepping over in three steps this is possible when actuation is applied according to the optimization results presented.
Machine Learning-Based Object Detection System Using PIR Sensor

Summary— An intrusion prevention system using a digital Pyroelectric Infra-Red (PIR) sensor produces an error with an object, not a human. To solve this error, this research suggests an analog PIR sensor and an object detection system using machine learning. The analog PIR sensor provides an output based on various voltage scales within a certain area rather than producing binary outputs using a threshold value. From samples of an analog signal attained by using an analog PIR sensor, a Fast Fourier Transform (FFT) processed frequency is produced and used as a feature vector of the Artificial Convolutional Neural Network (CNN). The artificial CNN then studies the signal patterns of human motion and animal motion and detects whether it is a human or animal that intruded.
Hybrid AES Algorithm Using 16 Fiestel Based Network with Distinct Keys

: In this work, a method to improve the security of existing cryptographic system is proposed. Here hybrid AES algorithm which make use of AES with Feistel network and distinct keys are employed. This hybrid algorithm propose16 rounds for AES-128 thereby security is enhanced as compared to existing system. This algorithm use AES key generation method for standard AES 128 and a predefined key for feistel network. Confusion provided by this system is much better than the technology prevalent in the existing systems.
Proxy Based Collision System To Minimize Content Downloads Time And Energy Utilization

: In comparison, the back-pressure trimmer alternative, variable back pressure guidance, and the overall limited expected accumulation of these fixed access rates can be guaranteed. It has been shown that D-ORCD with one destination ensures a limited expected delay of these systems and under any permitted movement, provided that the speed of the calculations is fast enough according to traffic statistics. The trimmer guidance reduces the result of weak wireless connections by exploiting the nature of transmission for wireless transmission and also the diversity of paths. E-DIVBAR: When choosing the next sequence of one of the potential forwarders, E-DIVBAR sees the sum of the differential accumulation and the expected number of jumps to the destination. However, the current property to ignore the price towards the destination, become a nightmare approach, resulting in poor performance in low to moderate traffic. The main contribution of this document is to provide an opportunistic distributed routing policy with congestion diversity in which congestion details are integrated using the shortest distributed road calculations rather than the simple addition used in E-DIVBAR. We reveal that a similar analytical assurance can be obtained with regard to the optimal performance of D-ORCD. In particular, we tested the best performance of D-ORCD by looking at the convergence of D-ORCD with some central form of the formula.
Student practices developing needs statements for design problems

Needs statements are concise articulations of design problems that indicate what changes are necessary for the problem to be resolved. Engineering students are increasingly participating in design projects during which they are developing needs statements based on stakeholder and contextual data; however, few studies have investigated student conceptions about developing needs statements. For this study, we followed an undergraduate student team as they completed training on developing needs statements and then developed initial needs statements for future design projects. While participants consistently described how needs statements should Balance breadth and specificity and Avoid embedding solutions , participants struggled to apply these conceptions in practice. Participants also did not discuss incorporating measurable outcome criteria into needs statements, even though this recommended practice was emphasized in the team’s training. Based on these findings, we recommend that design instructors supplement needs statement pedagogy with concrete examples of effective and ineffective needs statements and use visual tools to illustrate different levels of needs statement breadth and specificity.
Preparation of anti-Pseudomonas bioactive films by embedding Lactobacillus casei ATCC 39392 in Sodium caseinate and Methyl cellulose matrices

Biodegradable films containing lactic acid bacteria (LAB) are considered as new tools for advanced methods of food storage. In this study, Lactobacillus casei ATCC 39392 ( L. casei 39392 ) was directly incorporated into a film formation solution of sodium caseinate (NaCas) and methyl cellulose (MC). The bioactive films were prepared in a manner to contain 10 6 CFU/cm 2 L. casei 39392. The moisture content, solubility in water, water vapor permeability (WVP), color, opacity, tensile strength, percentage of elongation at break, and the elastic modulus of the films were studied. The survival rate of L. casei 39392 was examined during 30 days of storage (5 °C, RH 75%) and the films inhibitory effect on the growth of Pseudomonas aeruginosa PTCC 10832 was also studied at 5 °C for 12 days. The presence of L. casei 39392 increased the film’s opacity and its WVP compared to the control (p ˂ 0.05). The survival rate of L. casei 39392 was higher in NaCas films than in methylcellulose films (p < 0.05). A higher inhibitory effect on the growth of P. aeruginosa 10832 (85.3%) was observed in the MC bioactive film, and this inhibitory effect became noticeable from the fourth day of storage onwards (p ˂ 0.05). Our results showed that the bioactive films containing L. casei 39392 could be used and recognized as biofilms containing natural preservatives. can be claimed that the bio-MC film had a stronger anti-pseudomonas effect for up to 6 days of chilled storage. The results of this study demonstrate the anti-pathogenic properties of these biofilms in vitro . Our findings engender a new approach to the natural preservation, and may be able to increase the shelf life of some food products such as meat and cheese.
A comparative study of the anticoagulation of arteriovenous flush by using argatroban and heparin after cardiovascular surgery

[Abstract] Objective To compare arteriovenous flush with heparin and argatroban and observe its effect on platelet counts, biochemical index and the incidence of thrombocytopenia (HIT). Methods Retrospective analysis for 746 cardiovascular surgery patients, who were divided into heparin group (350 cases, 10 mg heparin dissolved in 250 ml of saline) and argatroban group (396 cases, 2.5 mg argatroban dissolved in 250 ml saline). Monitoring the changes of platelet count, hepatic function, renal function and blood coagulation index, hemorrhage and thrombosis incidence were monitored in two groups. HIT related score, HIT incidence and complications were also recorded. Results There was no significant difference in basic clinical data between the two groups. There was no difference in platelet counts between the two groups before and after the operation, and the platelets of heparin group were significantly lower than that of the argatroban group on the first day and the 5th day after surgery. According to 4Ts score, 13 patients in heparin group got medium and high score of 4Ts, of whom 7 patients were positive for antibody (2.0%), and then standard anti-coagulation therapy was initiated for antibody positive patients. There were 5 patients in argatroban group getting medium and high score of 4Ts, and 2 were HIT antibody positive (0.5%). As such, the standard anti-coagulation therapy was also performed on these patients, and no bleeding event occurred. The total number of thrombosis events were more in the heparin group than in the argatroban group. There was no statistically significant difference between the two groups in hepatic, renal function index and coagulation index. Conclusions Postoperative routine use of arteriovenous flush with argatroban for anticoagulation has litte effect on platelet count, could reduce the incidence of HIT and does not increase the risk of bleeding.
9 40 80 11 v 1 3 A ug 1 99 4 Scaling of Reaction Zones in the A + B → ∅ Diffusion-Limited Reaction

We study reaction zones in three different versions of the A + B → ∅ system. For a steady state formed by opposing currents of A and B particles we derive scaling behavior via renormalization group analysis. By use of a previously developed analogy, these results are extended to the timedependent case of an initially segregated system. We also consider an initially mixed system, which forms reaction zones for dimension d < 4. In this case an extension of the steady-state analogy gives scaling results characterized by new exponents.
Characterization of Escherichia coli Strains Isolated from Diarrhea 1 Patients in São Paulo: Identification of Intermediate Virulence Factor 2 Profiles by Multiplex PCR 3

Intestinal pathogenic Escherichia coli is a major causative agent of severe diarrhea. 2 In this study the prevalence of different pathotypes among 702 Brazilian diarrhea E. 3 coli isolates was determined by multiplex PCR. Interestingly, most strains were 4 enteroaggregative E. coli (EAEC) followed by atypical EPEC (ATEC). Classical 5 EPEC strains were not detected.
Quercetin Inhibits Epithelial-to-Mesenchymal Transition (EMT) Process and Promotes Apoptosis in Prostate Cancer via Downregulating lncRNA MALAT1

Background: Prostate cancer (PC) is one of the most common carcinomas in men worldwide. The lack of effective therapies urges the development of novel therapeutic options against PC. Quercetin (Quer) isa ﬂ avonoid compound that hasbeen shown to effectively inhibit PCin vitro and in vivo. However, the underlying mechanisms await elucidation. Long non-coding RNA MALAT1 has been reported as an oncogenic target in multiple types of cancers, including PC. Previous data showed that quercetin promoted the apoptosis of ﬁ broblast-like synoviocytes by upregulating MALAT1 in rheumatoid arthritis. However, we speculate that mechanisms are different in PC. Materials and Methods: Human PC cell line PC-3 and its xenograft tumor were chosen as in vitro and in vivo models for PC. A series of in vitro and in vivo functional experiments were carried out to elucidate the role of MALAT1 in quercetin treatment against PC. Western blot was performed to measure the expression of related proteins to explore underlying molecular mechanisms. Results: We showed for the ﬁ rst time that MALAT1 expression was signi ﬁ cantly downregulated in quercetin-treated PC cells in a dose- and time-dependent manner. Also, quercetin inhibited the proliferation of PC cells and the growth of xenograft tumors. Moreover, quercetin suppressed EMT process, promoted apoptosis and deactivated PI3K/Akt signaling pathway during the progression of PC. MALAT1 overexpression in PC cells resulted in the resistance against quercetin treatment. Conclusion: Our study illustrated, for the ﬁ rst time, that MALAT1 played an important role in quercetin treatment against PC by inhibiting EMT process and promoting apoptosis, providing a new molecular basis for the application of quercetin in PC treatment.
THE NECESSITY OF FORMING SUPERFLEXIBLE COMPANIES IN KAZAKHSTAN

The article discusses the concept of «super-flexibility» and principles of super-flexible companies studied by H. Bahrami and S. Evans during their work in the Silicon Valley. Considering the pace and trends of Kazakhstan’s business transformation the authors of the article have concluded that the principles and models of super-flexible organizational structures can become a methodological basis for managing companies in Kazakhstan and that would increase the country’s competitiveness in the future. Companies that adhere to the principles of super-flexible companies will have the ability to quickly and effectively respond to the situation as well as be able to resist the pressure from the external environment. Based on the researches of H. Bakhromi and S. Evans on superflexible companies, questionnaires were compiled and the first executives of the companies were interviewed, were revealed the prereq-uisites and necessity of forming superflexible companies in Kazakhstan. The authors concluded that if managers of companies in Kazakhstan will use the principles of super-flexible companies, they will be able to respond quickly to changes and will be able to take leading positions on the market.
Inﬂuence of Particle Nonsphericity on the Size Distribution Measurement of Submicrometer Mineral Dust by Use of Optical Particle Counter

− This paper addresses the issue of measuring the size distribution of nonspherical mineral dust particles by use of an optical particle counter （ OPC ） on the basis of comparison with transmission electron microscopic （ TEM ） analysis by a laboratory experiment and the theoretical computation of light scattering by nonspherical particles. The dust particles were monodispersed in the electrical mobility radius of 0 . 25 and 0 . 5 µ m and their size distribution were measured with the OPC and TEM and compared. The volume equivalent mode radii obtained with the OPC was 0 . 06 − 0 . 09 µ m larger than that obtained with the TEM. The size distribution width （ standard deviation ） obtained with the OPC was 5 − 13 ％ larger than that obtained with the TEM. Theoretical computation of the light scattering by triaxial spheroids showed the large variation in the light scattering intensity depending on the particle orientation, which can result in the large size distribution width obtained with the OPC. These results show that particle nonsphericity critically affects the measurement of dust by use of the OPC and care should be taken in utilizing the measured size distribution.
MULTI-SCALE REPRESENTATION OF DEFORMATIONS VIA WAVELET TRANSFORM ON BELTRAMI COEFFICIENTS

Analyzing the deformation pattern of an object is crucial in various ﬁelds, such as in computer visions and medical imaging. A deformation can be considered as a combination of local and global deformations at diﬀerent locations. To fully understand the deformation pattern, extracting the deformation of various scales and locations is necessary. We propose an algorithm for the multi-scale decomposition of a deformation using quasi-conformal theories. A deformation of an object can be described as a diﬀeomorphism. The diﬀeomorphism can then be represented by its associated Beltrami coeﬃcient (BC), which measures the local geometric (conformality) distortion of the deformation. The BC is a complex-valued function deﬁned on the source domain. By applying the wavelet transform on the BC, the BC can be decomposed into diﬀerent components of diﬀerent frequencies compactly supported in diﬀerent sub-domains. Quasi-conformal maps associated to different components of the BC can be reconstructed by solving the Beltrami’s equation. A multi-scale decomposition of the deformation can then be constructed. We test the proposed algorithm on synthetic examples as well as real medical data. Experimental results show the eﬃcacy of our proposed model to decompose a deformation at multiple scales and locations.
Brazilian Thoracic Association Consensus on Sleep-disordered Breathing

ABSTRACT Sleep is essential for the proper functioning of all individuals. Sleep-disordered breathing can occur at any age and is a common reason for medical visits. The objective of this consensus is to update knowledge about the main causes of sleep-disordered breathing in adult and pediatric populations, with an emphasis on obstructive sleep apnea. Obstructive sleep apnea is an extremely prevalent but often underdiagnosed disease. It is often accompanied by comorbidities, notably cardiovascular, metabolic, and neurocognitive disorders, which have a significant impact on quality of life and mortality rates. Therefore, to create this consensus, the Sleep-Disordered Breathing Department of the Brazilian Thoracic Association brought together 14 experts with recognized, proven experience in sleep-disordered breathing.
Management of medullary carcinoma of the thyroid: a review

Medullary thyroid carcinoma (MTC) is an uncommon malignancy of neuroendocrine origin derived from the parafollicular C cells. Although infrequent, the interest in this cancer exceeds its incidence owing to its distinctive features and its characteristic association with other endocrine tumors. Although the majority of MTCs are sporadic, hereditary varieties occur in isolation or as a part of multiple endocrine neoplasia type 2 syndrome (MEN 2). Currently, complete surgical resection of the tumor and nodal metastases with a curative intent remains the mainstay of therapy. The role of adjuvant therapy is limited, although radiotherapy and newer targeted therapies are routinely used for metastatic disease. The lack of consensus in the available guidance regarding the most appropriate diagnostic, therapeutic and follow-up strategies has caused substantial variability in clinical practice. Therefore, this review summarizes the latest available evidence and guidelines on the management of MTC with an emphasis on diagnosis, surgical treatment and follow-up.