Miracle-dz/UniFAR-FTUs huggingface dataset:
A PERCEPTIONAL STUDY ON NATURE OF NURSES’ MOTIVATION AND JOB SATISFACTION IN GHANAIAN HEALTHCARE SECTOR: A CASE STUDY OF THE KORLE-BU TEACHING HOSPITAL IN ACCRA

The purpose of this analysis is to describe challenges of nurses' work motivation and job satisfaction and examine the strategies of minimising their effects on performance of active nursing staffs from the perception of staff nurses. This information would be worthwhile for the growth of motivation and job satisfaction policies and further research into nurses' work motivation. A comprehensive assessment of the research literature was conducted. The study focused on the Korle-Bu Teaching Hospital. The entire study espoused a qualitative method with a case study design through in-depth interviews and focus group discussions of a total of forty (40) respondents comprising ten (10) strategic informers specially chosen due to their excelling function in the execution of nurses’ motivation and job satisfaction policies at the Korle-Bu Teaching Hospital Community. The research revealed that mismanagement of the hospital’s resources, huge economic resources needed to be channelled into motivation of nurses, inadequate logistical supplies to work with in saving lives, poor conditions of work and of service, intermittent intimidation of subordinate nurses, inability of nurses to express their views on issues affecting their welfare and the lack of medical plan for nurses were some of challenges affecting nurses motivation and job satisfaction at the Korle-Bu Teaching Hospital. The study applauds that nurses’ opinions must be sought when it comes to issues of motivation and job satisfaction which in itself serves as a motivator. The study also endorses that nurses’ preferences for different benefits vary with their ages, marital status and so on, and Correspondence concerning this paper should be addressed to: ___________________________________________________________________ therefore, must be factored into motivation and job satisfaction policies of the hospital. It is crucial to reiterate that for motivation and job satisfaction to be able to achieve their desired ultimate goals, it is necessary for the hospital to recognise and “prioritise” the individual needs in order to satisfy them appropriately to promote job satisfaction, thereby minimising the myriad of challenges confronting nurses’ motivation and job satisfaction at the Korle-Bu Teaching Hospital in Accra.
The strategy formulation practices of a newly appointed top management team

Strategic management is one of the core responsibilities of Top Management Teams (TMT). Unlike established TMTs, newly appointed TMTs may lack the expertise and the routines for effective strategy development. Little is known about how such teams engage in strategy making, and how well they succeed in formulating effective strategies. While this is a common situation, for instance, when high-growth SMEs start adopting more formal strategic management processes, it has received only limited attention in strategy research. Based on the strategy-as-practice framework, this study intended to gain insight into the practices that newly appointed TMTs employ to formulate a new strategy and into the effect of these practices on the formulated strategy. A group of nine managers, who were promoted from operative roles to form a new TMT, was followed for a seven-month period. Qualitative data were collected through participant observation and face-to-face interviews. Document analysis was used for the analysis of the formulated strategy. The results of the study suggested that cohesion development in a newly appointed TMT may hinder strategic exploration and ideation practices. Newly appointed TMT members also appeared to limit broader organizational participation in the strategy process. Moreover, being promoted from operative roles to strategic roles, TMT members tended to focus on internal matters. As a result, the strategy formulated by the newly appointed TMT failed to address the firm’s competitive position, but, instead, emphasized internal change. It was proposed that newly appointed TMTs should establish group cohesion and develop proper collaboration practices before engaging in strategic projects. The findings of the study contribute to the knowledge on the effects of TMT tenure and group cohesion on strategy formulation. Further research could validate the findings in strategy implementation processes and study the impact of organizational collaboration on strategy formulation. Keywords/tags Strategy, Strategy Formulation, Strategy as Practice, Top Management Team, Tenure
Class features as probes

Claims: (i) Class features are present in morphology: They are needed to predict the choice of inflection marker for a given stem in morphology (gender, phonological, semantic features of the stem do not suffice). (ii) Class features are binary (e.g., [ ±α], [±β]), not privative (e.g., I, II): They combine to yield the standard inflection classes (by underspecification, natural classes of inflection classes can be formed that permit a systematic account of syncretism across inflection classes). (iii) Class features are uninterpretable in syntax: They do not project, and syntactic operations do not refer to them. (iv) Class features are absent in syntax: Their presence in syntax would violate the Legibility Condition. (v) Class features act as probes on noun stems that trigger a morphological Agree operation with an inflection marker that acts as a goal before syntax is reached (in the same way that, e.g., LF-uninterpretable φ-features on T trigger movement in syntax before LF is reached). (vi) A pre-syntactic approach to class-driven inflectional morphology respects both the Legibility Condition and the Inclusiveness Condition; inneror post-syntactic approaches violate at least one of these conditions.
Electromagnetic Field Quantization in Time-Dependent Dielectric Media

We present a Gupta-Bleuler quantization scheme for the electromagnetic field in time-dependent dielectric media. Starting from the Maxwell equations, a generalization of the Lorentz gauge condition adapted to time varying dielectrics is derived. Using this gauge, a Gupta-Bleuler approach to quantize all polarizations of the radiation field and the corresponding constraint condition are introduced. This new approach is different from the quantized electromagnetic field in vacuum in the sense that here the contributions of unphysical photons cannot be thoroughly eliminated, which further lead to a surface charge density. Finally, a discussion of potential experimental tests and possible implication is also made.
MiceAntigen with Intranasal Administration to Responses Against Hepatitis B Surface Enhancer of Systemic and Mucosal Immune Cutting Edge: CpG DNA Is a Potent

Mucosal immunity is difﬁcult to induce with subunit vaccines unless such vaccines are administered with a mucosal adjuvant such as cholera toxin (CT); however, CT is toxic in humans. Synthetic oligodeoxynucleotides containing immunostimulatory CpG motifs (CpG) are potent adjuvants for the induction of Th1-like systemic immune responses against parenterally delivered proteins. Here, we show in mice that intranasal delivery of hepatitis B surface Ag, which alone has no effect, elicits good immune responses when given with CpG oligodeoxynucleotides and/or CT. Overall, CpG is superior to CT for the induction of humoral and cell-mediated systemic immunity as well as mucosal immune responses (IgA) at local (lung) and distant (feces) sites. Furthermore, CpG and CT act synergis-tically, giving stronger responses than those observed with 10 times more of either adjuvant alone. Ab isotypes were predominantly IgG1 (Th2-like) with CT, mixed IgG1/IgG2a (Th0) with CpG, and predominantly IgG2a (Th1-like) with CpG and CT together. The Journal of Immunology, 1998, 161: 4463– 4466. (1, immunization,
Effectiveness of Four Step Approach for Procedures (Skills) Teaching: Randomized Control Study Dr.Dhaval J Parmar

Introduction: Clinical skills development is an essential component of the education of a competent physician. Skill teaching with 4 step approach requires evidences to prove its superiority in better skill acquisition & retention as compared to traditional methods. Method: Randomized controlled Double-blinded cross over group study carried out on2 groups of randomly selected fourth term medical students using 2 teachers to teach 2 different procedure by traditional versus four step approach. Skill acquisition for each procedure was assessed by Observed Structured Practical Examination (OSPE). Pre-designed validated feedback form was used to rate both the method on five point Likert scale. Result: Better skill acquisition with statistically significant difference was shown, when taught by four step approach compared with traditional method irrespective of the group. Students ‘perceptions on different aspects of teaching was significantly positive for 4 step approach. Conclusion: Four step approach is both a more effective & efficient teaching method than traditional method for skill acquisition, which is perceived as bringing confidence, comfort & satisfaction. Study proves improvement in short term recall. To check long term retention, longitudinal study is required.
Gam m a irradiation or CD4 + T cell depletion causes reactivation of latent Salm onella enterica serovar Typhim urium infection in C3H/HeN m ice

Salmonella is a gram-negative pathogen that can cause a range of diseases in both animals and man varying from mild diarrhea to severe disseminated infections like typhoid fever. Upon infection, a host develops an immune response to limit bacterial growth and kill and eliminate the pathogen. Salmonella has evolved mechanisms to evade the host immune system and remain dormant within the body, only to reappear (reactivate) at a later time point when the immune system is abated. The exact mechanism by which Salmonella is able to persist is unknown, but evading the immune response likely plays an important role. W e have developed an in vivo model for studying reactivation of Salmonella enterica serovar Typhim urium infection in mice. Upon subcutaneous infection, C3H/HeN (Ity r ) mice showed an increase in bacterial numbers in livers and spleens reaching a peak on day 19. After full recovery of the infection, these mice were irradiated or depleted for CD4 + T cells. The mice showed a decrease in numbers of leukocytes and CD4 + T cells, respectively, and displayed a secondary infection peak in livers and spleens with a course similar to the primary infection. From this we concluded that CD4 + T cells are involved in active suppression of S. enterica serovar Typhimurium during persistency. The role of CD4 + T cells during primary infection with S. enterica serovar Typhimurium is well established. This is the first study to describe a role of CD4 + T cells during the phase of latent S. enterica serovar Typhimurium infection.
Edinburgh Rate-limiting steps in yeast protein translation

SUMMARY Deep sequencing now provides detailed snapshots of ribosome occupancy on mRNAs. We leverage these data to parameterize a computational model of translation, keeping track of every ribosome, tRNA, and mRNA molecule in a yeast cell. We determine the parameter regimes in which fast initiation or high codon bias in a transgene increases protein yield and infer the initiation rates of endogenous Saccharomyces cerevisiae genes, which vary by several orders of magnitude and correlate with 5 0 mRNA folding energies. Our model recapitulates the previously reported 5 0 -to-3 0 ramp of decreasing ribosome densities, although our analysis shows that this ramp is caused by rapid initiation of short genes rather than slow codons at the start of transcripts. We conclude that protein production in healthy yeast cells is typically limited by the availability of free ribosomes, whereas protein production under periods of stress can sometimes be rescued by reducing initiation or elongation rates.
Innovation Activities and Employment Level: An Empirical Assessment of Russian Manufacturing Companies

: The study analysis the impact of innovation on employment in Russian industry. Because innovation, by nature, has an oppositely directed influence on employment level, the impact of product and process innovations is considered separately. To this end, we study overcompensate and displacement effects. The first one refers to the replacement of labour with technology, and the second one refers to the growth of employment caused by the emergence of product innovation and the corresponding expansion of production. It is found that the growth in costs of process innovation causes a decrease in employment and the increase in innovative production (product innovation) positively affects the level of employment.
Psychology of Personality: Real and Virtual Context SOCIAL SUCCESS AS A PSYCHOLOGICAL PHENOMENON

The article discusses the specificity of adolescents’ perception of social success and presents its role in personal development. Being shaped from the early age period and throughout the whole life, social success affects the quality of life and peculiarities of a person’s self-efficacy. It is proved that the increased interest in studying social success is facilitated by the growing attention to the problem of personal changes, an increase in the environmental “challenges” faced by human abilities, as well as the need for a quick response to changes in society. The authors pay special attention to the analysis of social success as one of the main indicators of person’s self-fulfillment in conditions modern society, a category of personality psychology that broadens knowledge about the phenomenology of mental properties formation and development. The study involved 75 respondents (1 st and 2 nd year students with majors in psychological and pedagogical education). The purpose of the empirical study was to identify the basic features of social success image, as well as the study of young people’s subjective assessment of socially successful individuals. To solve the tasks set, we used the “Successful person” methodology and the author's questionnaire “Psychological portrait of a successful person”. The results of the study show that in adolescence, the image of social success is dominated by a humanistic orientation (benevolence, responsiveness, the ability to sacrifice). The authors proved the predominance of moral standards and rules, high intelligence, critical thinking and perseverance in the psychological portrait of a socially successful person.
Assessing the Environmental Impact: A Case of Business Process Analysis in the Automotive Industry

— Sustainability management is has been in the focus of the enterprises for several years now. Communal and private organizations are interested in sustainable solutions and practices for their operations. Software systems and their underlying business processes are ubiquitous and fundamental for most of the organizations of our industrial society. Hence, sustainability aspects must be integrated into the information systems architecture and into the business process life cycle. Using the action research approach for the environmentally focused business analysis of an automotive supplier we provide insights on how measuring the environmental effect of a business process can affect its optimization. We also show how a more process aware software can generate enhance environmental indicators beyond its own resource use optimization. By including environmental indicators into the classic process performance measuring this approach allows researchers and practitioners integrating environmental performance goals into the processes and their analysis.
Origins of a 350-Kilobase Genomic Duplication in Mycobacterium tuberculosis and Its Impact on Virulence

In the present study, we have investigated the evolution and impact on virulence of a 350-kb genomic duplication present in the most recently evolved members of the Mycobacterium tuberculosis East Asian lineage. In a mouse model of infection, comparing HN878 subclones HN878-27 (no duplication) and HN878-45 (with the 350-kb duplication) revealed that the latter is impaired for in vivo growth during the initial 3 weeks of infection. Furthermore, the median survival time of mice infected with isolate HN878-45 is signiﬁcantly longer (77 days) than that of mice infected with HN878-27. Whole-genome sequencing of both isolates failed to reveal any mutational events other than the duplication that could account for such a substantial difference in virulence. Although we and others had previously speculated that the 350-kb duplication arose in response to some form of host-applied selective pressure (P. Domenech, G. S. Kolly, L. Leon-Solis, A. Fallow, M. B. Reed, J. Bacteriol. 192:4562–4570, 2010, and B. Weiner, J. Gomez, T. C. R. M. Warren, B.
Thermal depolarization and electromechanical hardening in Zn2+-doped Na1/2Bi1/2TiO3-BaTiO3

Na 1/2 Bi 1/2 TiO 3 -based materials have been earmarked for one of the first large-volume applications of lead-free piezoceramics in high-power ultrasonics. Zn 2+ -doping is demonstrated as a viable route to enhance the thermal depolarization temperature and electromechanically harden (1- y )Na 1/2 Bi 1/2 TiO 3 - y BaTiO 3 (NBT100 y BT) with a maximum achievable operating temperature of 150 °C and mechanical quality factor of 627 for 1 mole % Zn 2+ -doped NBT6BT. Although quenching from sintering temperatures has been recently touted to enhance T F-R , with quenching the doped compositions featuring an additional increase in T F-R by 17 °C, it exhibits negligible effect on the electromechanical properties. The effect is rationalized considering the missing influence on conductivity and therefore, negligible changes in the defect chemistry upon quenching. High-resolution diffraction indicates that Zn 2+ -doped samples favor the tetragonal phase with enhanced lattice distortion, further corroborated by 23 Na Nuclear Magnetic Resonance investigations.
Safety of Endoscopic-Ultrasound-Guided Portal Injection Chemotherapy using Drug-Eluting Microbeads in a Porcine Model

: Background and Aims : Patients with diffuse liver metastases have systemic chemotherapy as their only treatment option. We developed Endoscopic Ultrasound (EUS)-guided portal injection chemotherapy (EPIC) to increase drug levels in hepatic tissue as a novel new liver directed therapy. Methods : Sixteen anesthetized pigs were treated with 50 mg of irinotecan (n=8) or doxorubicin (n=8). Half (n=4) of the animals in each drug group were treated with EPIC-injected microbeads or EUS-guided chemotherapy without beads into the inferior vena cava (control). Animals were observed twice daily for 7 days for signs of clinical toxicities. Tissue samples were harvested for histology and drug levels. Blood counts and chemistries were determined pre-treatment and at 7 days. Results : No toxicities as evidenced by abnormal animal behavior were observed. No significant changes occurred in blood chemistry or blood counts in the irinotecan groups. For doxorubicin, systemic injection significantly decreased albumin, hemoglobin, and white blood cell count ( P <.05), with no changes after EPIC. Hepatic histology showed mild foreign body reactions around the beads. No significant histologic changes were seen in other tissue sites. Neither irinotecan nor SN-38 was detectable at 7 days. For doxorubicin, no drug was detected in the plasma or bone marrow. The mean (SD) doxorubicin hepatic levels were non-significantly increased with vs control (181 [241] vs 151 [67] ng/g). Cardiac doxorubicin levels were significantly lower with EPIC (15 [4] vs 138 [48] ng/g; P =.02). Conclusions : EPIC using drug-eluting microbeads was safe in this animal model. For doxorubicin, EPIC may be safer than systemic injection.
PTT_A_285832 61..66

Department of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran-Dr. Hasan Sadikin Hospital, Bandung 40161, Indonesia Abstract: Psoriasis may manifest as severe hyperkeratotic lesions resembling an oyster shell called ostraceous psoriasis (OP). This type of psoriasis is extremely rare and is often associated with psoriatic arthritis (PA). Cases of OP associated with PA in children have never been reported before. We reported a 9-year-old girl with hyperkeratotic lesions resembling an oyster shell all over the body accompanied with swelling on joints of both fingers, knee joints, and ankle. Histopathological examination supported the diagnosis of OP. The diagnosis of PA was established according to the Classification Criteria for Psoriatic Arthritis (CASPAR). Significant improvements of the skin lesions and joints involved were observed within 44 days after the beginning of treatment with cyclosporine and a combination of high potent topical steroid with emollient. OP associated with PA is uncommonly seen in children. High potent corticosteroid combined with emollient showed good result in skin improvement with low side effects. In addition, cyclosporine can be a good choice of systemic therapy for OP with PA in children.
Observation of Magnetic Reconnection in a Region of Strong Turbulence

We examine a rare and interesting observation of magnetic reconnection embedded in a large-scale region of strong turbulence in which magnetic field annihilation is energizing ions and electrons. The magnetic reconnection event is in Earth’s magnetotail and is associated with enhanced energetic particle fluxes indicating local particle acceleration. Despite substantial electric and magnetic field fluctuations throughout the surrounding, large-scale region, the ongoing magnetic reconnection has many similar properties to laminar, 2D magnetic reconnection including Hall electric fields, Hall magnetic fields, a thin electron current sheet, and ion and electron jets. Notably, the electron jet emerging from the electron diffusion region (EDR) appears to transport sufficient off-diagonal momentum to infer that off-diagonal electron stress can support the reconnection electric field in the EDR even in a turbulent environment. Although the electron jet appears to be briefly (∼1 s) deflected or possibly interrupted by an electromagnetic disturbance, the reconnection appears to otherwise continue for a long period (∼30 minutes) as evidenced by a persistent ion jet. This particular finding implies that the fundamental electron-scale processes inside of the EDR in turbulent magnetic reconnection are not necessarily distinct from those in laminar magnetic reconnection. These observations provide direct confirmation that magnetic reconnection can not only be responsible for but also can continue in regions of large-scale turbulence. Because the electric and magnetic fields of strong turbulence are linked to particle acceleration, it follows that particle acceleration also can continue as a consequence of turbulent magnetic reconnection.