Miracle-dz/UniFAR-FTUs huggingface dataset:
Short-Term Adaptive Emergency Call Volume Prediction

Sudden periods of extreme and persistent changes in the distribution of medical emergencies can trigger resource planning inefficiencies for Emergency Medical Services, causing delayed responses and increased waiting times. Predicting such changes and reacting adaptively can alleviate these adversarial impacts. In this paper, we propose a simple framework to enhance historically calibrated call volume models, the latter a focus of study in the arrival estimation literature, to give more accurate short-term prediction by refitting their residuals into time series. We discuss some justification of our framework from the perspective of doubly stochastic Poisson processes. We illustrate our methodology in predicting the hourly call volume to the 911 call center during the Covid-19 pandemic in NYC, showing how it could improve the performance of baseline historical estimators by close to 50% measured by the out-of-sample prediction error for the next hour.
pengembangan model latihan shooting dalam permainan sepakbola di sekolah sepakboala indonesia muda (im) malang

Penelitian ini bertujuan mengembangkan model latihan shooting dalam permainan sepakbola di Sekolah Sepakbola Indonesia Muda (IM) Malang. Prosedur pengembangannya adalah sebagai berikut: (1) Penentuan ide-ide, (2) Penulisan naskah media (produk), (3) Evaluasi Produk, (4) Revisi Produk I, (5) Produksi prototipe, (6) Uji coba prototipe, dengan mengujicobakan hasil revisi produk I, (7) Revisi Produk II, (8) Reproduksi, penyempurnaan produk untuk menuju produk akhir. Subyek uji coba terdiri dari (1) Tinjauan ahli, terdiri dari 2 orang ahli yaitu ahli di bidang kepelatihan dan pelatih sepakbola, (2) Uji coba kelompok kecil adalah menggunakan 10 orang pemain yang diambil secara random sampling, dan (3) Uji coba kelompok besar. Penelitian menghasilkan buku panduan model latihan shooting yang berisikan 10 model yaitu : (1) shooting dengan kombinasi lari sprint, (2) shooting dengan kombinasi keeping bola (3) shooting dengan kombinasi teknik passing, (4) shooting dengan dribbling bola, (5) shooting dengan kombinasi dribbling, passing dan keeping bola, (6) shooting dengan kombinasi gerakan tanpa bola, (7) l shooting dengan kombinasi passing dan penempatan pemain bertahan 1, (8) shooting dengan kombinasi passing dan penempatan pemain bertahan 2, (9) shooting dengan kombinasi passing dan penempatan pemain bertahan 3, (10) shooting dengan kombinasi membuka ruang tembak. Kata kunci: pengembangan, model latihan, shooting dalam permainan sepakbola
The Impact of Self-Efficacy and Perceived Value on Customer Engagement under Live Streaming Commerce Environment

Live streaming commerce, which has led to the emergence of new forms of social commerce called live streaming, has already improved the performance of many social commerce streamers. Live streaming commerce is an emerging business model that has blended the functions of e-commerce and live webcasting. The total sales volume will increase when the streamers and the customers communicate in the real-time interaction platform. In live streaming commerce, customer engagement behavior has been beneficial for realizing the value of live streaming commerce, which scholars have studied and valued. However, internal and external factors often affect customer engagement behavior, and most of the existing research focuses on only one aspect. This article will analyze internal and external influencing factors (internal influencing factors are based on self-efficacy theory, and external influencing factors are based on value-based adoption models) and their interactions to get a broad conclusion. To understand customer engagement behavior in the live streaming commerce with comprehensive research, the article constructs a customer engagement model in the live streaming commerce environment and uses structural equations for empirical testing. In applying self-efficacy theory, it is committed to distinguishing the functional logic between general self-efficacy and special self-efficacy and understanding the mechanism of special self-efficacy, namely, the influence mechanism of live streaming self-efficacy on perceived value and customer engagement in specific situations. The research results show that general self-efficacy positively influences perceived usefulness, perceived entertainment, and live streaming commerce self-efficacy, while perceived usefulness, perceived entertainment, and live streaming commerce self-efficacy positively affect perceived value, live streaming commerce self-efficacy, and self-efficacy. Perceived value has a positive and significant impact on customer engagement behavior. This research explains the influencing factors and mechanism of customer engagement in the live streaming commerce environment from the internal and external perspectives, enriches the theoretical research on customer engagement, and provides practical guidance for customer engagement behavior in the live streaming commerce environment.
An NMF solution to the TTC 2020 roundtrip engineering case

This paper presents a solution to the Roundtrip Engineering case at the Transformation Tool Contest (TTC) 2020. I demonstrate how synchronization blocks can be easily used to specify the relationships in a bidirectional manner. Through a superimposition concept, the migrations can concentrate on those parts of the metamodel that have actually changed. The performance results on the provided model shows that the solution has a very good performance on the provided input models, although these are very small.
Manipulating Interface Design Features Affects Children's Stop-And-Think Behaviours in a Counterintuitive-Problem Game

The human–computer interaction (HCI) design of educational technologies influences cognitive behaviour, so it is imperative to assess how different HCI strategies support intended behaviour. We developed a neuroscience-inspired game that trains children's use of “stopping-and-thinking” (S&T)—an inhibitory control-related behaviour—in the context of counterintuitive science problems. We tested the efficacy of four HCI features in supporting S&T: (1) a readiness mechanic, (2) motion cues, (3) colour cues, and (4) rewards/penalties. In a randomised eye-tracking trial with 45 7-to-8-year-olds, we found that the readiness mechanic increased S&T duration, that motion and colour cues proved equally effective at promoting S&T, that combining symbolic colour with the readiness mechanic may have a cumulative effect, and that rewards/penalties may have distracted children from S&T. Additionally, S&T duration was related to in-game performance. Our results underscore the importance of interdisciplinary approaches to educational technology research that actively investigates how HCI impacts intended learning behaviours.
Possible Business Models Using the NSR

The new era of Northern Sea Route (NSR) is changing the global logistics environment. In response to this phenomenon, this study explores possible ways for South Korea to use the NSR commercialization. The study highlights trade of wood pellets and promotion of cruise industry as promising two business models which enable to accelerate the NSR commercialization. The findings in this study for removing risks and barriers related to the models can be summarized as follows. First, a closer examination of ports and their related infrastructure along the coasts of the Arctic Ocean is required. Second, target and demand for the logistics infrastructure required should be identified. Third, enormous investments into the construction of ports and related logistics infrastructures are required. Fourth, transport · logistics network should be connected as a whole. Fifth, in order to maximize benefits and profits, business models relevant to NSR require considerable effort for further development. The South Korean government and the local governments should establish strategies by which business models can be utilized more effectively.
Disrupted Functional Connectivity of the Amygdala Predicts the Efficacy of Non-steroidal Anti-inflammatory Drugs in Migraineurs Without Aura

Machine learning (ML) has been largely applied for predicting migraine classification. However, the prediction of efficacy of non-steroidal anti-inflammatory drugs (NSAIDs) in migraine is still in the early stages. This study aims to evaluate whether the combination of machine learning and amygdala-related functional features could help predict the efficacy of NSAIDs in patients with migraine without aura (MwoA). A total of 70 MwoA patients were enrolled for the study, including patients with an effective response to NSAIDs (M-eNSAIDs, n = 35) and MwoA patients with ineffective response to NSAIDs (M-ieNSAIDs, n = 35). Furthermore, 33 healthy controls (HCs) were matched for age, sex, and education level. The study participants were subjected to resting-state functional magnetic resonance imaging (fMRI) scanning. Disrupted functional connectivity (FC) patterns from amygdala-based FC analysis and clinical characteristics were considered features that could promote classification through multivariable logistic regression (MLR) and support vector machine (SVM) for predicting the efficacy of NSAIDs. Further, receiver operating characteristic (ROC) curves were drawn to evaluate the predictive ability of the models. The M-eNSAIDs group exhibited enhanced FC with ipsilateral calcarine sulcus (CAL), superior parietal gyrus (SPG), paracentral lobule (PCL), and contralateral superior frontal gyrus (SFG) in the left amygdala. However, the M-eNSAIDs group showed decreased FC with ipsilateral caudate nucleus (CAU), compared to the M-ieNSAIDs group. Moreover, the M-eNSAIDs group showed higher FC with left pre-central gyrus (PreCG) and post-central gyrus (PoCG) compared to HCs. In contrast, the M-ieNSAIDs group showed lower FC with the left anterior cingulate cortex (ACC) and right SFG. Furthermore, the MwoA patients showed increased FC with the left middle frontal gyrus (MFG) in the right amygdala compared to HCs. The disrupted left amygdala-related FC patterns exhibited significant correlations with migraine characteristics in the M-ieNSAIDs group. The MLR and SVM models discriminated clinical efficacy of NSAIDs with an area under the curve (AUC) of 0.891 and 0.896, sensitivity of 0.971 and 0.833, and specificity of 0.629 and 0.875, respectively. These findings suggest that the efficacy of NSAIDs in migraine could be predicted using ML algorithm. Furthermore, this study highlights the role of amygdala-related neural function in revealing underlying migraine-related neuroimaging mechanisms.
Efficacy and Safety of Empagliflozin on Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis

Objective Clinical trials have recently shown a connection between nonalcoholic fatty liver disease (NAFLD) and empagliflozin. This paper aimed at comprehensively assessing the effectiveness and security of empagliflozin in NAFLD patients. Methods PubMed, Embase, Web of Science, Cochrane Library, CNKI, CBM, Wan-Fang digital database, VIP, and WHO ICTRP were searched for randomized controlled trials (RCTs) on the role of empagliflozin in NAFLD from inception to November 2, 2021. For continuous dating, we used values of mean differences (MD) to present. Results A total of four articles involving 244 NAFLD patients were included. Compared with the control group, empagliflozin could significantly reduce the body mass index (BMI) (MD: −0.98 [95% CI: −1.87, −0.10], p = 0.03), liver stiffness measurement (LSM) (MD: 0.49 [95% CI: −0.93, −0.06], p = 0.03), aspartate aminotransferase (AST) (MD: −3.10 [95% CI: −6.18, −0.02], p = 0.05), homeostasis model assessment of insulin resistance (HOMA-IR) (MD: −0.45 [95% CI: −0.90, 0.00], p = 0.05) of the treatment group. Conclusions Empagliflozin can improve body composition, insulin resistance, and liver fibrosis and decrease the hepatic enzymes in patients with NAFLD. Empagliflozin emerges as a new option for treating patients with NAFLD. However, further research shall determine the efficacy and safety of empagliflozin in NAFLD.
Determinants of Dyslipidemia in Africa: A Systematic Review and Meta-Analysis

Background Dyslipidemia is a common public health problem in Africa. It has emerged as an important cardiovascular risk factor. It has been steadily increasing due to economic growth, urbanization, and unhealthy dietary pattern. Therefore, it is essential to identify determinants of dyslipidemia to prevent the condition and reduce its long-term sequel. Methods Combinations of search terms with Boolean operators were used to retrieve studies from PubMed, EMBASE, Cochrane Database, Cinahl, Scopus, Mednar, and Google Scholar. The methodological quality of each article was evaluated based on the 2017 Joanna Briggs Institute (JBI) Critical Appraisal checklist for prevalence studies. After evaluation of each study against these criteria, studies with a minimum score of 7 or above out of 9 JBI checklists were included. We included articles presented in the English language. The Cochrane Q test was used to assess the heterogeneity across studies. The visual assessment of publication bias was done by creating a funnel plot. The possible causes of heterogeneity were explored by subgroup analyses. Egger's weighted regression test was used to assess the presence of publication bias. Statistical analyses were done by using the STATA software version 14. Result A total of 24 articles involving 37,902 participants from 10 African countries were included. The overall pooled prevalence of dyslipidemia was 52.8 (95% CI 40.8–64.9). Individuals with a body mass index (BMI) >25.0 kg/m2 and waist circumference (WC) >94 cm were, respectively, 2.36 (95% CI (1.33–4.18), p < 0.001) and 2.33 (95% CI (0.75–0.29) p < 0.001) times more likely to develop dyslipidemia than those with lower values. Furthermore, patients with diabetes mellitus (DM) and hypertension (HTN) were 2.32 (95% CI (0.89–6.05) p < 0.001) and 2.05 (95% CI (1.31–3.21), p < 0.001) times more likely to present with dyslipidemia than non-diabetic patients and those without HTN. Conclusion This study revealed that the prevalence of dyslipidemia is relatively high among study participants in African countries and the independent predictors of dyslipidemia were BMI >25.0 kg/m2, WC > 94 cm, raised blood glucose level, and raised blood pressure. Therefore, there should be a pressing public health measure to prevent, identify, and treat dyslipidemia with the special emphasis on obese, diabetic, and hypertensive patients.
Barriers to Achieving Conservation Engineering Goals in Commercial Trawl Fisheries

The advancement of conservation practices in global trawl fisheries has been impeded in part by a lack of a collective understanding of the most relevant and broad-scale knowledge-needs, along with the identification of potential barriers to addressing these knowledge-needs. Using both an online survey and an in-person workshop, we engaged a diversity of fishing industry stakeholders including scientists, technology companies, trawl net makers, and fishermen working with North Pacific, United States, trawl fisheries to identify and prioritize areas in which further knowledge is required for successful implementation of conservation engineering practices. In addition, we identified barriers to addressing these knowledge-needs. Knowledge-needs related to fishing gear performance were identified among the top priorities, including several areas targeted at improving fishing efficiency that could further advance the sustainability of well-managed trawl fisheries. To better understand the composition and behavior of target versus non-target catch, workshop participants identified the importance of closing data and technology gaps. This highlights areas for potential collaboration between fishermen, researchers, and technology companies to address research prioritized by the end-user. Further, results from the workshop emphasized a need for industry-driven training and workshops focused on elevating fishermen skill for newer entrants through peer-learning and knowledge-sharing to achieve objectives like better non-target avoidance and increased fishing efficiency of the target species. Addressing these prioritized knowledge-needs, by first working toward overcoming the industry-identified barriers, may aid in increasing uptake of conservation practices, thereby contributing to the long-term sustainability of these fisheries and associated social-ecological systems.
Processing and Subcellular Localization of the Hepatitis E Virus Replicase: Identification of Candidate Viral Factories

Hepatitis E virus (HEV) is the major cause of acute hepatitis worldwide. HEV is a positive-sense RNA virus expressing three open reading frames (ORFs). ORF1 encodes the ORF1 non–structural polyprotein, the viral replicase which transcribes the full-length genome and a subgenomic RNA that encodes the structural ORF2 and ORF3 proteins. The present study is focused on the replication step with the aim to determine whether the ORF1 polyprotein is processed during the HEV lifecycle and to identify where the replication takes place inside the host cell. As no commercial antibody recognizes ORF1 in HEV-replicating cells, we aimed at inserting epitope tags within the ORF1 protein without impacting the virus replication efficacy. Two insertion sites located in the hypervariable region were thus selected to tolerate the V5 epitope while preserving HEV replication efficacy. Once integrated into the infectious full-length Kernow C-1 p6 strain, the V5 epitopes did neither impact the replication of genomic nor the production of subgenomic RNA. Also, the V5-tagged viral particles remained as infectious as the wildtype particles to Huh-7.5 cells. Next, the expression pattern of the V5-tagged ORF1 was compared in heterologous expression and replicative HEV systems. A high molecular weight protein (180 kDa) that was expressed in all three systems and that likely corresponds to the unprocessed form of ORF1 was detected up to 25 days after electroporation in the p6 cell culture system. Additionally, less abundant products of lower molecular weights were detected in both in cytoplasmic and nuclear compartments. Concurrently, the V5-tagged ORF1 was localized by confocal microscopy inside the cell nucleus but also as compact perinuclear substructures in which ORF2 and ORF3 proteins were detected. Importantly, using in situ hybridization (RNAScope ®), positive and negative-strand HEV RNAs were localized in the perinuclear substructures of HEV-producing cells. Finally, by simultaneous detection of HEV genomic RNAs and viral proteins in these substructures, we identified candidate HEV factories.
Melanin Promotes Spore Production in the Rice Blast Fungus Magnaporthe oryzae

The rice blast pathogen, Magnaporthe oryzae, spreads through spores and invades rice through appressoria. Melanin is necessary for an appressorium to penetrate plant cells, but there are many unknown aspects of its role in fungal conidiation. In this study, we confirmed that melanin promotes spore production in M. oryzae, and that this effect is related to the background melanin content of wild-type strains. In the wild-type 70-15 strain with low melanin content of aerial hyphae, increased melanin synthesis promoted sporulation. In contrast, increased melanin synthesis in the wild-type Guy11 strain, which has higher melanin content, did not promote sporulation. The transcription factor Cnf1 (conidial production negative regulatory factor 1), which negatively regulates melanin synthesis, has opposite effects in conidiophore differentiation of Guy11 and 70-15. Deletion of CNF1 did not abolish the defects of Δcos1 and Δhox2 (where COS1/conidiophore stalk-less 1 or HOX2/homeodomain protein 2 was deleted) in conidiation, while increased the conidiation of Δgcc1 and Δgcf3 (where GCC1/growth, conidiation and cell wall regulatory factor 1, or GCF3/growth and conidiation regulatory factor 3 was deleted). Pig1 (pigment of Magnaporthe 1) regulates the melanin synthesis of hyphae but not of conidiophores, spores, or appressoria. Deletion of the same gene in different wild-type strains can lead to different phenotypes, partly because of differences in melanin content between fungal strains. Overall, this study reveals the functional diversity and complexity of melanin in different M. oryzae strains.
Diabetes Epidemiology Among Adults in Port-au-Prince, Haiti: A Cross-Sectional Study

Introduction Diabetes mellitus is a chronic noncommunicable disease associated with death and major disability, with increasing prevalence in low- and middle-income countries. There is limited population-based data about diabetes in Haiti. The objective of this study was to assess the prevalence of diabetes and associated factors among adults in Port-au-Prince, Haiti using a population-based cohort. Methods This study analyzes cross-sectional enrollment data from the population-based Haiti Cardiovascular Disease Cohort Study, conducted using multistage sampling with global positioning system waypoints in census blocks in the metropolitan area of Port-au-Prince, Haiti. A total of 3,005 adults ≥18 years old were enrolled from March 2019 to August 2021. We collected socio-demographic data, health-related behaviors, and clinical data using standardized questionnaires. Diabetes was defined as any of the following criteria: enrollment fasting glucose value ≥ 126 mg/dL or non-fasting glucose ≥ 200 mg/dL, patient self-report of taking diabetes medications, or study physician diagnosis of diabetes based on clinical evaluation. Results Among 2985 (99.3%) with complete diabetes data, median age was 40 years, 58.1% were female, and 17.2% were obese. The prevalence of diabetes was 5.4% crude, and 5.2% age standardized. In unadjusted analysis, older age, higher body mass index (BMI), low physical activity, low education were associated with a higher odds of diabetes. After multivariable logistic regression, older age [60+ vs 18-29, Odds Ratio (OR)17.7, 95% CI 6.6 to 47.9] and higher BMI (obese vs normal/underweight, OR 2.7, 95% CI 1.7 to 4.4) remained statistically significantly associated with higher odds of diabetes. Conclusion The prevalence of diabetes was relatively low among adults in Port-au-Prince, but much higher among certain groups (participants who were older and obese). The Haitian health system should be strengthened to prevent, diagnose, and treat diabetes among high-risk groups.