Miracle-dz/UniFAR-FTUs huggingface dataset:
The $D^+_s \to K^+ \pi^+ \pi^-$ reaction and the scalar $f_0(500)$, $f_0(980)$ and $K^*_0 (700)$ resonances

We develop a model to reproduce the mass distributions of pairs of mesons in the Cabibbo-suppressed $D^+_s \to K^+ \pi^+ \pi^-$ decay. The largest contributions to the process comes from the $D^+_s \to K^+ \rho^0$ and $D^+_s \to K^{*0} \pi^+$ decay modes, but the $D^+_s \to K^*_0(1430) \pi^+$ and $D^+_s \to K^+ f_0(1370)$ modes also play a moderate role and all of them are introduced empirically. Instead, the contribution of the $f_0(500)$, $f_0(980)$ and $K^*_0(700)$ resonances is introduced dynamically by looking at the decay modes at the quark level, hadronizing $q \bar{q}$ pairs to give two mesons, and allowing these mesons to interact to finally produce the $K^+ \pi^+ \pi^-$ final state. These last three modes are correlated by means of only one parameter. We obtain a fair reproduction of the experimental data for the three mass distributions as well as the relative weight of the three light scalar mesons, which we see as further support for the nature of these states as dynamically generated from the interaction of pseudoscalar mesons.
Detailed equilibrium and dynamical tides: impact on circularization and synchronization in open clusters

Binary stars evolve into chemically-peculiar objects and are a major driver of the Galactic enrichment of heavy elements. During their evolution they undergo interactions, including tides, that circularize orbits and synchronize stellar spins, impacting both individual systems and stellar populations. Using Zahn’s tidal theory and mesa main-sequence model grids, we derive the governing parameters λlm and E2, and implement them in the new mint library of the stellar population code binary_c. Our mint equilibrium tides are 2 to 5 times more efficient than the ubiquitous bse prescriptions while the radiative-tide efficiency drops sharply with increasing age. We also implement precise initial distributions based on bias-corrected observations. We assess the impact of tides and initial orbital-parameter distributions on circularization and synchronization in eight open clusters, comparing synthetic populations and observations through a bootstrapping method. We find that changing the tidal prescription yields no statistically-significant improvement as both calculations typically lie within 0. 5σ. The initial distribution, especially the primordial concentration of systems at log10(P/d) ≈ 0.8, e ≈ 0.05 dominates the statistics even when artificially increasing tidal strength. This confirms the inefficiency of tides on the main sequence and shows that constraining tidal-efficiency parameters using the e − log10(P/d) distribution alone is difficult or impossible. Orbital synchronization carries a more striking age-dependent signature of tidal interactions. In M35 we find twice as many synchronized rotators in our mint calculation as with bse. This measure of tidal efficiency is verifiable with combined measurements of orbital parameters and stellar spins.
AllSight: A Low-Cost and High-Resolution Round Tactile Sensor With Zero-Shot Learning Capability

Tactile sensing is a necessary capability for a robotic hand to perform fine manipulations and interact with the environment. Optical sensors are a promising solution for high-resolution contact estimation. Nevertheless, they are usually not easy to fabricate and require individual calibration in order to acquire sufficient accuracy. In this letter, we propose AllSight, an optical tactile sensor with a round 3D structure designed for robotic in-hand manipulation tasks. AllSight is mostly 3D printed including a novel and simplified fabrication processes. This makes it low-cost, modular, durable and in the size of a human thumb while with a large contact surface. We show the ability of AllSight to learn and estimate a full contact state, i.e., contact position, forces and torsion. With that, an experimental benchmark between various configurations of illumination and contact elastomers are provided. Furthermore, the robust design of AllSight provides it with a unique zero-shot capability such that a practitioner can fabricate the open-source design and have a ready-to-use state estimation model. A set of experiments demonstrates the accurate state estimation performance of AllSight.
Tree expansions of some Lie idempotents}

We prove that the Catalan Lie idempotent $D_n(a,b)$, introduced in [Menous {\it et al.}, Adv. Appl. Math. 51 (2013), 177] can be refined by introducing $n$ independent parameters $a_0,\ldots,a_{n-1}$ and that the coefficient of each monomial is itself a Lie idempotent in the descent algebra. These new idempotents are multiplicity-free sums of subsets of the Poincar\'e-Birkhoff-Witt basis of the Lie module. These results are obtained by embedding noncommutative symmetric functions into the dual noncommutative Connes-Kreimer algebra, which also allows us to interpret, and rederive in a simpler way, Chapoton's results on a two-parameter tree expanded series.
Promising substitute of inconsistent algal alginates: exploring the biocompatible properties of di-O-acetylated, poly-L-guluronate-deficient alginate from soil bacterium Pseudomonas aeruginosa CMG1418

The structural inconsistencies in commercial algal alginates have limited their reliability and quality for various applications. Therefore, the biosynthesis of structurally consistent alginates is crucial to replace the algal alginates. Thus, this study aimed to investigate the structural and alginate's structural and functional properties of Pseudomonas aeruginosa CMG1418 as a substitute. To achieve this, the CMG1418 alginates were physiochemically characterized using various techniques such as transmission electron microscopy, Fourier-transform infrared 1H-NMR, 13C-NMR, and gel permeation chromatography. The synthesized CMG1418 alginate was then subjected to standard tests to evaluate its biocompatibility, emulsification, hydrophilic, flocculation, gelling, and rheological properties. The analytical studies revealed that CMG1418 alginate is an extracellular and polydisperse polymer with a molecular weight range of 20 000–250 000 Da. It comprises 76% poly-(1–4)-β-D-mannuronic acid (M-blocks), no poly-α-L-guluronate (G-blocks), 12% alternating sequences of β-D-mannuronic acid and α-L-guluronic acid (poly-MG/GM-blocks), 12% MGM-blocks, 172 degrees of polymerization, and di-O-acetylation of M-residues. Interestingly, CMG1418 alginate did not show any cytotoxic or antimetabolic activity. Moreover, compared to algal alginates, CMG1418 alginate exhibited higher and more stable flocculation efficiencies (70–90%) and viscosities (4500–4760 cP) over a wide range of pH and temperatures. Additionally, it displayed soft to flexible gelling abilities and higher water-holding capacities (375%). It also showed thermodynamically more stable emulsifying activities (99–100%) that surpassed the algal alginates and commercial emulsifying agents. However, only divalent and multivalent cations could slightly increase viscosity, gelling, and flocculation. In conclusion, this study explored a structurally di-O-acetylated and poly-G-blocks-deficient, biocompatible alginate, and its pH and thermostable functional properties. This research suggests that CMG1418 alginate is a superior and more reliable substitute for algal alginates in various applications, such as viscosifying, soft gelling, flocculating, emulsifying, and water-holding.
Editorial: Chronic pain management and psychological distress in older adults

COPYRIGHT © 2023 Scarlata and Mancini. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. Editorial: Chronic pain management and psychological distress in older adults
Interaction between gut microbiota metabolites and dietary components in lipid metabolism and metabolic diseases

Gut microbiota composition has caused perplexity in developing precision therapy to cure metabolic disorders. However, recent research has focused on using daily diet and natural bioactive compounds to correct gut microbiota dysbiosis and regulate host metabolism. Complex interactions between the gut microbiota and dietary compounds disrupt or integrate the gut barrier and lipid metabolism. In this review, we investigate the role of diet and bioactive natural compounds in gut microbiota dysbiosis and also the modulation of lipid metabolism by their metabolites. Recent studies have revealed that diet, natural compounds and phytochemicals impact significantly on lipid metabolism in animals and humans. These findings suggest that dietary components or natural bioactive compounds have a significant impact on microbial dysbiosis linked to metabolic diseases. The interaction between dietary components or natural bioactive compounds and gut microbiota metabolites can regulate lipid metabolism. Additionally, natural products can shape the gut microbiota and improve barrier integrity by interacting with gut metabolites and their precursors, even in unfavourable conditions, potentially contributing to the alignment of host physiology.
Problèmes aux valeurs propres non linéaires dans les inéquations variaionnelles : Etude locale

ON S'INTERESSE A UNE CLASSE D'INEQUATIONS VARIATIONNELLES ELLIPTIQUES, ASSOCIEES A UN PROBLEME D'OBSTACLE ET DEPENDANT D'UN PARAMETRE LAMBDA : A(A,V-U) >OU= SOM::(OMEGA )LAMBDA F(U)(V-U)DX POUR TOUT V APPARTIENT A K, U APPARTIENT A K=(W APPARTIENT A H::(0)**(1)(OMEGA )/W OU= PSI P.P. SUR OMEGA ). UNE TELLE INEQUATION ADMET AU MOINS UNE BRANCHE DE SOLUTIONS EQUATION ET UNE BRANCHE DE SOLUTIONS INEQUATIONS. ON CHERCHE A CONNAITRE LA STRUCTURE LOCALE DES BRANCHES INEQUATIONS. GRACE A UN PROCESSUS DE LINEARISATION "CONIQUE" ON CLASSE LES POINTS DE LA BRANCHE INEQUATION EN POINTS REGULIERS OU SINGULIERS. AU VOISINAGE D'UN POINT REGULIER, ON MONTRE QUE LES SOLUTIONS ADMETTENT UN DEVELOPPEMENT SELON LAMBDA . PUIS ON ETUDIE LE COMPORTEMENT LOCAL DES SOLUTIONS AU VOISINAGE D'UN POINT SINGULIER VERIFIANT CERTAINES HYPOTHESES, QUI SONT A RAPPROCHER DE CELLES FAITES POUR LES EQUATIONS ET QUI ASSURENT QU'ON A DU POINT DE RETOURNEMENT. ON MONTRE QUE, DANS CERTAINS CAS, IL EXISTE UN TEL POINT SINGULIER, SUR LA BRANCHE DE SOLUTIONS MAXIMALES. LES BRANCHES EQUATIONS ET INEQUATIONS SONT RELIEES PAR UN POINT APPELE POINT DE TRANSITION. ON FAIT UNE ETUDE PLUS FINE AU VOISINAGE DE CE POINT. UNE ETUDE DES DIVERSES CONDITIONS INTRODUITES POUR L'ETUDE LOCALE, MONTRE QU'ELLES SONT FORTEMENT LIEES A UNE CONDITION TYPE STABILITE. ILLUSTRATION NUMERIQUE SUR QUELQUES PROBLEMES D'OBSTACLE
Inhibition of synaptic transmission by anandamide precursor 20:4-NAPE is mediated by TRPV1 receptors under inflammatory conditions

Transient receptor potential ion channel, vanilloid subfamily, type 1 (TRPV1) cation channel, and cannabinoid receptor 1 (CB1) are essential in the modulation of nociceptive signaling in the spinal cord dorsal horn that underlies different pathological pain states. TRPV1 and CB1 receptors share the endogenous agonist anandamide (AEA), produced from N-arachidonoylphosphatidylethanolamine (20:4-NAPE). We investigated the effect of the anandamide precursor 20:4-NAPE on synaptic activity in naive and inflammatory conditions. Patch-clamp recordings of miniature excitatory postsynaptic currents (mEPSCs) from superficial dorsal horn neurons in rat acute spinal cord slices were used. Peripheral inflammation was induced by subcutaneous injection of carrageenan. Under naive conditions, mEPSCs frequency (0.96 ± 0.11 Hz) was significantly decreased after 20 μM 20:4-NAPE application (55.3 ± 7.4%). This 20:4-NAPE-induced inhibition was blocked by anandamide-synthesizing enzyme N-acyl phosphatidylethanolamine phospholipase D (NAPE-PLD) inhibitor LEI-401. In addition, the inhibition was prevented by the CB1 receptor antagonist PF 514273 (0.2 μM) but not by the TRPV1 receptor antagonist SB 366791 (10 μM). Under inflammatory conditions, 20:4-NAPE (20 μM) also exhibited a significant inhibitory effect (74.5 ± 8.9%) on the mEPSCs frequency that was prevented by the TRPV1 receptor antagonist SB 366791 but not by PF 514273 application. Our results show that 20:4-NAPE application has a significant modulatory effect on spinal cord nociceptive signaling that is mediated by both TRPV1 and CB1 presynaptic receptors, whereas peripheral inflammation changes the underlying mechanism. The switch between TRPV1 and CB1 receptor activation by the AEA precursor 20:4-NAPE during inflammation may play an important role in nociceptive processing, hence the development of pathological pain.
The impact of Lego® Therapy on cognitive skills in Autism Spectrum Disorders: a brief discussion

Over the years, several interventions have been implemented, including Lego® Therapy, with the aim of supporting and implementing social and communication skills impairments in Autism Spectrum Disorders (ASD). Although recent studies have shown that the ability to learn implicitly is preserved in ASDs, no study related to Lego® Therapy has analyzed whether and how this training can also affect aspects not directly treated. In this study, we report a first attempt of assessment of Lego® Therapy's effect on the specific area of cognitive skills in an ASD child. Over a period of 12 months, a child with ASD had weekly meetings with an expert operator of Lego® aiming to improve the child's ability to communicate, reduce impulsiveness and hyper verbalism, and encourage pro-social behavior. The intervention resulted in positive outcomes that were assessed after 12 months.
Vitamin D deficiency and risk of recurrent aphthous stomatitis: updated meta-analysis with trial sequential analysis

Background Growing evidence suggests a significant association between vitamin D deficiency and RAS. Hence, the present meta-analysis and trial sequential analysis sought to investigate the potential association between low serum vitamin D levels and RAS. Methods PubMed, Scopus, Embase, and Web of Science were comprehensively searched on December 1st, 2022 to retrieve all relevant studies. The grey literature was also searched via ProQuest. All case-control studies on the association between vitamin D and RAS were considered. The quality appraisal of the included studies was done using Newcastle-Ottawa scale. RevMan 5.0 and trial sequential analysis (TSA) programs were used for analyses. Results A total of 14 case-control studies with 1468 subjects (721 RAS patients and 747 controls) were included. The pooled data revealed a significant association between low serum levels of vitamin D and the risk of RAS (mean difference = – 8.73, 95% CI: – 12.02 to – 5.44, I2 = 94%, P < 0.00001). Additionally, TSA findings indicated that the current studies surpassed the required information size, confirming that the differences were reliable. Conclusion The available evidence suggests that Vitamin D deficiency may have a role in the pathogenesis of RAS. Therefore, evaluation of vitamin D should be considered in RAS patients. Additionally, the results support the possibility of using vitamin D supplements in the management of RAS patients with inadequate serum levels of vitamin D. Future interventional studies are required to evaluate the benefits of vitamin D replacement in prevention and treatment of RAS.
Nanofibers with homogeneous heparin distribution and protracted release profile for vascular tissue engineering

In clinic, controlling acute coagulation after small-diameter vessel grafts transplantation is considered a primary problem. The combination of heparin with high anticoagulant efficiency and polyurethane fiber with good compliance is a good choice for vascular materials. However, blending water-soluble heparin with fat-soluble poly (ester-ether-urethane) urea elastomer (PEEUU) uniformly and preparing nanofibers tubular grafts with uniform morphology is a huge challenge. In this research, we have compounded PEEUU with optimized constant concentration of heparin by homogeneous emulsion blending, then spun into the hybrid PEEUU/heparin nanofibers tubular graft (H-PHNF) for replacing rats’ abdominal aorta in situ for comprehensive performance evaluation. The in vitro results demonstrated that H-PHNF was of uniform microstructure, moderate wettability, matched mechanical properties, reliable cytocompatibility, and strongest ability to promote endothelial growth. Replacement of resected abdominal artery with the H-PHNF in rat showed that the graft was capable of homogeneous hybrid heparin and significantly promoted the stabilization of vascular smooth muscle cells (VSMCs) as well as stabilizing the blood microenvironment. This research demonstrates the H-PHNF with substantial patency, indicating their potential for vascular tissue engineering.
High-risk children and social isolation: the importance of family functioning

High-risk newborns are exposed to neonatal conditions such as prematurity, very low birth weight, and congenital malformations that can affect development and behavior. Coronavirus disease 2019 (COVID-19) restraint and control measures have been identified as important stressor events and cumulative risk factors for behavioral changes in these children. This study examined social isolation-related factors that contribute to internalizing and externalizing behavior problems in children already at risk for neurodevelopmental disorders. This cross-sectional, multicenter study included 113 children (18 months to 9 years) who were followed in reference services for neonatal follow-up in tertiary units of the public health system in the city of Rio de Janeiro, Brazil. Behavior was assessed using the child behavior checklist, and a structured questionnaire was used to assess sociodemographic aspects. In the bivariate analysis, prematurity was associated with externalizing problems and change in eating habits with internalizing problems. The logistic model indicated that both parents having completed high school and both sharing care of the child were protective factors for behavioral problems; however, reports of sleep problems and living with another child were risk factors. In conclusion, the study identified internalizing and externalizing behavior problems related to prematurity and aspects of family structure and routine in children at risk. The findings confirm the importance of family functioning for child health and family-centered interventions.
GNA12 regulates C5a-induced migration by downregulating C5aR1-PLCβ2-PI3K-AKT-ERK1/2 signaling

Gna12 has been identified as one of the reported inflammatory bowel disease (IBD) susceptibility genes in genome-wide association studies (GWAS). However, the function of GNA12 in intestinal homeostasis remains unknown. Here we report that GNA12, a G-protein α subunit, regulates C5a-induced migration in macrophages. Deficiency of GNA12 results in enhanced migration induced by C5a in macrophages. Mechanistically, GNA12 suppresses C5a-induced migration by downregulating the C5aR1-PLCβ2-PI3K-AKT-ERK1/2 signaling. Therefore, our study reveals that GNA12 is an anti-inflammatory factor, which might alleviate the development of inflammation by inhibiting the excessive chemotactic migration of macrophages.
Optical sensors of bulk refractive index using optical fiber resonators

Optical fiber resonator (OFR) sensor is presented for bulk liquid refractive index (RI) sensing. The sensing mechanism relies on the spectral shifts of whispering gallery modes (WGMs) of OFRs which are excited using a tapered fiber. OFR liquid RI sensor is fully characterized using water solutions of ethanol and ethylene glycol (EG). A good agreement is achieved between the analytical calculations and experimental results for both TE and TM polarizations. The detection limit for bulk RI is calculated to be between 2.7 – 4.7 × 10−5 refractive index unit (RIU). The OFR sensor provides a robust, easy-to-fabricate and sensitive liquid refractive index sensor which can be employed in lab-on-a-chip applications.
COVERAGE PERFORMANCE OF COGNITIVE RADIO NETWORKS POWERED BY RENEWABLE ENERGY

We analyse the coverage performance of cognitive radio networks powered by renewable energy. Particularly, with an energy harvesting module and energy storage module, the primary transmitters (PTs) and the secondary transmitters (STs) are assumed to be able to collect ambient renewables, and store them in batteries for future use. Upon harvesting sufficient energy, the corresponding PTs and STs (denoted by eligible PTs and STs) are then allowed to access the spectrum according to their respective medium access control (MAC) protocols. For the primary network, an Aloha-type MAC protocol is considered, under which the eligible PTs make independent decisions to access the spectrum with probability $\unicode[STIX]{x1D70C}_{p}$ . By applying tools from stochastic geometry, we characterize the transmission probability of the STs. Then, with the obtained results of transmission probability, we evaluate the coverage (transmission nonoutage) performance of the overlay CR network powered by renewable energy. Simulations are also provided to validate our analysis.
Surgical External Iliac Artery Access for Transcatheter Aortic Valve Replacement Is a Safe, Suitable Alternative to Common Femoral Artery Access

Background Many patients undergoing transcatheter aortic valve replacement (TAVR) have peripheral artery disease necessitating surgical access. This study reviews the preoperative risk factors, procedural characteristics, and outcomes in patients undergoing surgical common femoral artery (CFA) and external iliac artery (EIA) access through a retro-inguinal groin incision for TAVR. Methods A single-center TAVR database was retrospectively analyzed for patients undergoing surgical cutdown (January 1, 2016 - December 31, 2020). Access sites were evaluated on preoperative imaging. Data on demographics, imaging, procedural characteristics, and outcomes were collected. The vascular surgeon selected the cutdown site. Results A hundred and thirty TAVR patients had surgical cutdown. The choice of access site was either the common femoral artery (82 patients, 63%) or the iliac artery (48 patients, 37%). There was no difference in age, BMI, or medical risk factors. There was no difference in iliac diameter or circumferential iliac calcium. In the iliac group, there was a smaller mean CFA size and a higher incidence of circumferential CFA calcium. In the femoral group, there was: a lower mean sheath-to-CFA ratio, a trend toward increased unplanned endarterectomy, and a higher incidence of 30-day readmission. There was no difference in adjunct procedure use. Conclusion EIA surgical access had similar complication rates and length of stay with a reduced tendency for unplanned endarterectomy when compared to CFA access. The EIA is a suitable access site for TAVR in select patients.