Miracle-dz/UniFAR-FTUs huggingface dataset:
On sex, drugs, and alcohol: a mixed-method analysis of youth posts on social media in the United States

ABSTRACT In the digital neighborhood, Black and Hispanic youth communicate about issues they face, including sex and substance use. This population of young people is also disproportionately burdened by negative consequences associated with sex and substance use behaviors even when their behavior is less risky. Given the increased likelihood of negative outcomes, we investigated how young people communicate about these behaviors in their digital social networks. This mixed-methods study integrates a behavioral survey with a machine learning-supported, qualitative content analysis of one year of Facebook and Twitter posts from 50 Black and Hispanic youth, with feedback from a youth advisory board. Participants who had previously had sex or drank alcohol were more likely to post about sex or alcohol, respectively. Moreover, compared to male youth , female youth posted significantly more about sex in general and about STIs, HIV, and pregnancy . Posts about sexual behavior often discussed trust in sexual partners and gendered views of sex. Posts linked alcohol and marijuana with stress relief and coping withgrief, community violence, and distress. Understanding how youth think and communicate about sexual risk and substance use can inform the design of effective prevention efforts. IMPACT SUMMARY Prior State of Knowledge: Social media offers an excellent window into youth perspectives and the ways they broadcast and communicate about their lives, beliefs, and health behaviors to their networked peers. Novel Contributions: In this community-engaged study, we center the experiences of Black and Hispanic youth in their digital neighborhoods to understand how youth talk about sex, drugs and alcohol in their own words. We examined the interplay between posts, social identities and health behaviors. Practical Implications: For practitioners using social media in prevention efforts, integrating youth voices and expertise in the development of online prevention efforts may be more effective in identifying drivers of risk taking and supporting risk reduction behavior.
The effect of fall prevention education on fear of falling in patients with scheduled total knee arthroplasty: a quasi-experimental study

ABSTRACT The aim of this study is to determine the effect of fall prevention education given to patients with scheduled total knee arthroplasty (TKA) on their fear of falling in the postoperative period. The study had a quasi-experimental design. The study sample included 70 patients. Data were gathered with a patient characteristics form and the Falls Efficacy Scale-International (FES-I) at face to face interviews. The intervention group was given a brochure and face-to-face education about fall prevention before surgery. Activities such as the first mobilization, assisted walking, climbing stairs, getting out of bed and sitting in bed after the surgery were demonstrated and performed. Patients were followed up to 16 weeks after surgery. The mean age of the control and intervention groups, respectively; 62.26 ± 6.38 and 59.46 ± 7.33. The fear of falling scores before the operation and in the postoperative 6th-8th weeks were high in the intervention group (40.17 ± 8.32 and 31.71 ± 7.83 respectively) and the control group (44.14 ± 8.86 and 40.91 ± 8.43 respectively). The fear of falling scores in the postoperative 14th-16th weeks were high in the control group (37.2 ± 9.03) and moderate in the intervention group (26.42 ± 5.59). The scores for FES-I in the 6th-8th weeks and 14th-16th weeks after surgery were very significantly lower in the intervention group than in the control group(p < .001). The results of the study showed that the patients experienced a great fear of falling before and after surgery. It can be said that the education given reduces the fear of falling significantly and in the early period.
Comparative Study of the SEM Evaluation, EDX Assessment, Morphometric Analysis, and Cyclic Fatigue Resistance of Three Novel Brands of NiTi Alloy Endodontic Files

In this study, we compare and analyze the scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDX), morphometry and cyclic fatigue resistance of Endogal, PathMax, and Smarttrack novel brands of nickel–titanium (NiTi) alloy endodontic files. Material and Methods: Thirty sterile NiTi endodontic rotary files were randomly selected and assigned to one of the following study groups: A: 25.08 F2 Endogal (EDG) (n = 10); B: 25.08 F2 Path Max Pro (PMP) (n = 10); and C: 25.06 Smarttrack (ST) (n = 10). Dynamic cyclic fatigue tests were conducted using a cyclic fatigue device in stainless steel artificial root canal systems with an apical diameter of 250 µm, curvature angle of 60°, radius of curvature of 3 mm, and taper of 6%. Additionally, we analyzed the NiTi endodontic rotary files using EDX, SEM, and morphometry after micro-CT scanning. The results were analyzed using Weibull statistical analysis and ANOVA testing. Results: SEM, EDX, and morphometric analyses showed differences between the three novel brands of NiTi endodontic rotary files. Moreover, statistically significant differences were observed between the number of cycles to failure and time to failure of the three novel brands of NiTi endodontic rotary files (p < 0.001). Conclusions: Smarttrack NiTi alloy endodontic reciprocating files display greater resistance to cyclic fatigue than Endogal and Path Max Pro NiTi alloy endodontic rotary files, due to the reciprocating movement and metallurgical composition.
Musculoskeletal fitness and body composition of Newfoundland and Labrador offshore oil and gas workers

Musculoskeletal fitness and body composition has been well studied as it relates to an individual’s overall health in relation to non-communicable diseases such as cardiovascular disease, cancers, chronic respiratory diseases, and diabetes (World Health Organization, 2015). The objectives of this research were to investigate the current musculoskeletal fitness and body composition of the Newfoundland and Labrador (NL) Offshore Workforce and to determine how this population compares to the Canadian population. Eighty-nine men from the NL offshore workforce (mean ± standard deviation; height: 177.13 ± 6.77 cm, mass: 92.02 ± 16.07 kg, age: 42 ± 9.76 years) were included for analysis in this study. Data was collected offshore by a Definitions® wellness representative from five offshore industry companies. All measures were collected in accordance with the Canadian Physical Activity, Fitness & Lifestyle Approach Manual (Canadian Society for Exercise Physiology, 2004), the Physical Activity Training for Health manual (Canadian Society for Exercise Physiology, 2013) or Advanced Fitness Assessment And Exercise Prescription (Heyward & Gibson, 2010). Body composition measures included body mass index (BMI), waist circumference, and skin-folds. Musculoskeletal measures included push-ups, partial curl-ups, back extension, sit-and-reach, and grip strength. Participants were divided into two age groups: 20 – 39 and 40 – 59. Results from both groups showed that offshore workers have poor body composition, but have generally good musculoskeletal fitness compared to Canadian norms. However, both groups performed similarly on the musculoskeletal fitness tests. This means that a younger population has the physical strength and endurance of a population that is on average 14 years older. Overall, the results indicated the need to improve the overall body composition of the offshore workforce with ongoing development to maintain, or improve in some instances, musculoskeletal health. These results are an important starting point, whereby the Canadian Newfoundland and Labrador Offshore Petroleum Board can investigate the feasibility of offshore specific health and wellness programming that aims to improve the physical fitness of all offshore workers.
Research on user experience for in-vehicle infotainment

The rapid development of modern internet industry system has promoted a brand new revolution of vehicle design. Deriving from the field of computer interaction, the theory of User Experience (UX) design has grown up. While the InVehicle Infotainment (IVI), with a high connection with computer interaction, demanding the methods and flow of UX design urgently. Depending on the UX design project for the IVI of a certain homebred luxury car, this paper clearly puts forward the planning contents and organization flow of UX's activity. It has proposed Multi-dimensional user model, simulation of UX and hierarchical question bank. Combined with the case of `feedback guides correction' in actual project, it has summarized the methods of feedback processing. It has also introduced the conception of `Bank of UX design' for IVI, which will provide powerful guarantee of data for the efficient development of new product.
HuR Plays a Role in Double-Strand Break Repair in Pancreatic Cancer Cells and Regulates Functional BRCA1-Associated-Ring-Domain-1(BARD1) Isoforms

Simple Summary RNA binding proteins (RBPs) post-transcriptionally regulate and stabilize a variety of target mRNA transcripts. Human Antigen R (HuR) binds to several pro-survival mRNA transcripts and promotes tumor cell survival and chemotherapeutic resistance. Some of these targets are within the DNA damage repair pathway that help cells repair damaged DNA and allow them to proliferate. Homologous recombination repair is the preferred method of DNA repair in the cells. Here, we aim to understand if HuR regulates homologous recombination repair in pancreatic ductal adenocarcinoma (PDAC). Our analysis, using Ribonucleo-protein Immunoprecipitation (RNP-IP) coupled with microarray and RNA-sequencing studies, revealed that HuR binds BARD1 (BRCA-1 Associated Ring Domain 1) and regulates expression of BARD1 mRNA full length transcripts and alternative isoforms. Silencing BARD1 mRNA potentiated the DNA damage effects of clinically relevant drugs, olaparib and oxaliplatin, in PDAC cells. Together, this work underscores a transient regulatory DNA repair pathway (i.e., HuR—BARD1 mRNA), which is likely a PDAC therapeutic resistance mechanism. Abstract Human Antigen R (HuR/ELAVL1) is known to regulate stability of mRNAs involved in pancreatic ductal adenocarcinoma (PDAC) cell survival. Although several HuR targets are established, it is likely that many remain currently unknown. Here, we identified BARD1 mRNA as a novel target of HuR. Silencing HuR caused a >70% decrease in homologous recombination repair (HRR) efficiency as measured by the double-strand break repair (pDR-GFP reporter) assay. HuR-bound mRNAs extracted from RNP-immunoprecipitation and probed on a microarray, revealed a subset of HRR genes as putative HuR targets, including the BRCA1-Associated-Ring-Domain-1 (BARD1) (p < 0.005). BARD1 genetic alterations are infrequent in PDAC, and its context-dependent upregulation is poorly understood. Genetic silencing (siRNA and CRISPR knock-out) and pharmacological targeting of HuR inhibited both full length (FL) BARD1 and its functional isoforms (α, δ, Φ). Silencing BARD1 sensitized cells to olaparib and oxaliplatin; caused G2-M cell cycle arrest; and increased DNA-damage while decreasing HRR efficiency in cells. Exogenous overexpression of BARD1 in HuR-deficient cells partially rescued the HRR dysfunction, independent of an HuR pro-oncogenic function. Collectively, our findings demonstrate for the first time that BARD1 is a bona fide HuR target, which serves as an important regulatory point of the transient DNA-repair response in PDAC cells.
Quasi-parity-time symmetric dynamics in periodically driven two-level non-Hermitian system

In recent years, there have been intensive studies of non-Hermitian physics and parity–time (PT) symmetry due to their fundamental importance in theory and outstanding applications. A distinctive character in PT-symmetric system is phase transition (spontaneous PT-symmetrybreaking), i.e. an all-real energy spectrum changes into an all-complex one when the non-Hermitian parameter exceeds a certain threshold. However, the conditions for PT-symmetric system with real energy spectrum to occur are rather restrictive. The generalization of PT-symmetric potentials to wider classes of non-PT-symmetric complex potentials with all-real energy spectra is a currently important endeavor. A simple PT-symmetric two-level Floquet quantum system is now being actively explored, because it holds potential for the realization of non-unitary single-qubit quantum gate. However, studies of the evolution dynamics of non-PT-symmetric two-level non-Hermitian Floquet quantum system are still relatively rare.In this paper, we investigate the non-Hermitian physics of a periodically driven non-PT-symmetric two-level quantum system. By phase-space analysis, we find that there exist so-called pseudo fixed points in phase space representing the Floquet solutions with fixed population difference and a time-dependent relative phase between the two levels. According to these pseudo fixed points, we analytically construct a non-unitary evolution operator and then explore the dynamic behaviors of the non-PT-symmetric two-level quantum system in different parameter regions. We confirm both analytically and numerically that the two-level non-Hermitian Floquet quantum system, although it is non-parity-time-symmetric, still features a phase transition with the quasienergy spectrum changing from all-real to all-complex energy spectrum, just like the PT symmetric system. Furthermore, we reveal that a novel phenomenon called quasi-PT symmetric dynamics occurs in the time evolution process. The quasi-PT symmetric dynamics is so named in our paper, in the sense that the time-evolution of population probabilities in the non-PT-symmetric two-level system satisfies fully the time-space symmetry (PT symmetry), while time-evolution of the quantum state (containing the phase) does not meet such a PT symmetry, due to the fact that time-evolution of the phases of the probability amplitudes on the two levels violates the requirement for the PT symmetry.
Two Modulators of Skeletal Development: BMPs and Proteoglycans

During embryogenesis, skeletal development is tightly regulated by locally secreted growth factors that interact with proteoglycans (PGs) in the extracellular matrix (ECM). Bone morphogenetic proteins (BMPs) are multifunctional growth factors that play critical roles in cartilage maturation and bone formation. BMP signals are transduced from plasma membrane receptors to the nucleus through both canonical Smad and noncanonical p38 mitogen-activated protein kinase (MAPK) pathways. BMP signalling is modulated by a variety of endogenous and exogenous molecular mechanisms at different spatiotemporal levels and in both positive and negative manners. As an endogenous example, BMPs undergo extracellular regulation by PGs, which generally regulate the efficiency of ligand-receptor binding. BMP signalling can also be exogenously perturbed by a group of small molecule antagonists, such as dorsomorphin and its derivatives, that selectively bind to and inhibit the intracellular kinase domain of BMP type I receptors. In this review, we present a current understanding of BMPs and PGs functions in cartilage maturation and osteoblast differentiation, highlighting BMP–PG interactions. We also discuss the identification of highly selective small-molecule BMP receptor type I inhibitors. This review aims to shed light on the importance of BMP signalling and PGs in cartilage maturation and bone formation.
Using Full Pose Measurement for Serial Robot Calibration

To ensure smooth robot operations, parameters of its kinematic model and a registration transformation between robot base and world coordinate frame must be determined. Both tasks require data acquired by external sensors that can measure either 3D locations or full 6D poses. We show that use of full pose measurements leads to much smaller robot orientation errors when compared with the outcome of calibration and registration procedures based on 3D data only. Robot position errors are comparable for both types of data. The conclusion is based on extensive simulations of 7 degrees of freedom robot arm and different levels of pseudo-noise perturbing both positional and rotational components of pose.
Peran Kecerdasan Emosional terhadap Kesehatan Mental pada Emerging Adulthood

Kesehatan mental merupakan salah satu bentuk kesehatan yang berkaitan dengan kesejahteraan individu. Meski penting, adanya masalah kesehatan mental masih sering ditemukan, salah satunya pada individu yang mengalami transisi dari masa remaja menuju dewasa atau periode emerging adulthood. Dalam mengoperasionalisasikan kesehatan mental, terdapat salah satu bentuk yang bisa ditinjau yaitu melalui emosi, dimana emosi merupakan dasar dari kecerdasan emosional. Oleh karena itu, tujuan penelitian merujuk bagaimana pengaruh yang diberikan pada kecerdasan emosional terhadap kesehatan mental pada emerging adulthood. Penelitian dilakukan melalui survei dengan total 344 partisipan. Berdasarkan hasil penelitian, dapat dilihat jika kecerdasan emosional memiliki pengaruh yang signifikan (F(1)342=6,833; p=0,009; R2=0,020) terhadap kesehatan mental pada emerging adulthood sebesar 2%. Hal tersebut menjelaskan mengenai peningkatan kecerdasan emosional, dapat berperan dalam peningkatan kesehatan mental pada individu.
Services in Global Value Chains – An Insight into the Current Situation in the EU Member States

Global value chains (GVCs) consist of many production processes and phases/tasks that take place in different countries. The studies of the global value chains are mainly focused on manufactured products, often neglecting the role of services. In this paper, the emphasis is on the service sector, trade in services and the measurement of their participation in GVCs in the EU member states. There are four different ways, "modes of supply", to deliver services from a producer to the final customer. Official statistics include some of these modes, whereas some are hidden within the manufacturing process. According to the descriptive statistics analysis and presented data employed, it is clear that services trade is undervalued; services represent the majority of value added in the EU's GDP, but less than half of foreign trade; domestic value added in the service sector is higher than in manufacturing, which indicates the importance of domestic resources in the creation and export of services. EU industries are highly serviced and, interestingly, services contribute to more than 30 per cent of manufacturing production, with a higher share of foreign services.
COVID-19 Pandemic: The Impact of the Social Media Technology on Higher Education

The COVID-19 pandemic led universities to transform the traditional teaching methodologies into distance education. Therefore, social media has become progressively prominent as teaching and learning resources in universities. Several studies have been conducted for the development of social media as a learning tool. However, there is limited empirical evidence supporting this claim. The present study bridges the gap in the literature concerning the value of the use of social media in higher education. This research seeks to examine the impact of the use of social media in (a) enhancing teaching and learning in universities, (b) motivating and supporting students and (c) developing community connection. A qualitative methodology was adopted. Specifically, in-depth interviews were conducted to assess the effectiveness of social media on students learning in higher education. The results showed that the use of social media by higher educational institutions positively impacts the educational process by (a) promoting teaching and learning, (b) motivating students to be active participants, and (c) establishing connections in the university community. Some obstacles in the teaching and learning process were also identified. Future areas of research are proposed.
Effect of Broadband Infrastructure on Rural Household CO2 Emissions in China: A Quasi-Natural Experiment of a “Broadband Village”

This paper explores how broadband infrastructure affects rural household carbon dioxide emissions (HCE). Based on the Environmental Kuznets curve hypothesis, a quasi-natural experiment of a “Broadband Village” (B&V) in China is conducted. Panel data from 9,790 rural households were collected as part of the China Family Finance Survey (CHFS). The consumer lifestyle approach was used to calculate HCE and a Difference-in-Differences (DID) model was used to analyze the impact of a B and V pilot project on rural HCE. The results of DID model showed that B and V significantly increases rural HCE, with an influencing coefficient 1.7. Subsequently, Threshold Model was utilized to examine the nonlinear relationship between household broadband penetration and rural HCE. The results revealed the threshold effect between rural household broadband penetration and rural HCE. Namely, the growth effect of B and V to rural HCE would be much weaker, if rural household broadband penetration goes above a threshold level, 31.32%. Our analysis provides important insights for policymakers to formulate digital village and income redistribution policies to support rural carbon dioxide (CO2) emissions reductions.
Dual‐loop single dimension fuzzy‐based sliding mode control design for robust tracking of an underactuated quadrotor craft

This manuscript presents an intelligent control design for the helical trajectory tracking of an underactuated quadrotor. One may see that the entire kinematics and dynamics are derived using Newton Euler approach. Since the quadrotor is one of the nonlinear and underactuated systems (where degree of freedom is greater than the number of control inputs) and with the induction of unmodeled dynamic factors and uncertainties, it is a highly unstable system. To stabilize, the linear extended state observer is proposed along with dual‐loop single dimension fuzzy‐based sliding mode control (DLSDF‐SMC). The entire system has been partitioned into two subsystems, that is, translational and rotational subsystems. Within the rotational subsystem, the attitude controller is proposed using DLSDF‐SMC, whereas for translational subsystem, paper proposes the position control design based on the hyperbolic functions to avoid the gimbal lock and an issue of singularity. The simulation work for proposed algorithm is performed using MATLAB and Simulink that are compared with conventional sliding mode control (SMC) and fuzzy‐based SMC control techniques. In addition to this, one may also find the hardware configuration that validates the software results.
THE INFLUENCE OF SELF-ESTEEM, LONELINESS, AND SUICIDALITY ON SOCIAL MEDIA ADDICTION

The purpose of this study was to determine the relationship between self-esteem, loneliness, suicidality with social media addiction. University students (N = 198) were sampled by utilizing an online survey, using convenience sampling method. Five instruments were used, including the Social Media Addiction Scale (SMAS), Rosenberg Self-esteem Scale (RSE), University of California Los Angeles (UCLA) Loneliness Scale-3, and Yatt Suicide Attitude Scale (YSAS). In the multiple linear regression analysis, the regression model accounted for a significant 12.3% of the variance in social media addiction. Only self-esteem was a significant predictor of social media addiction. Lastly, loneliness and suicidality were not significantly associated with social media addiction. Treatment of social media addiction should take into consideration the evaluation and intervention of self-esteem issues among university students.