Miracle-dz/UniFAR-FTUs huggingface dataset:
Integrated and effective platform governance mode for managing construction muck waste for a circular economy

Construction waste is a type of solid waste that is inevitably produced in the process of urban development and has a dreadful environmental impact due to inadequate management of it by the public sector. The purpose of this paper is therefore to investigate platform governance as an alternative strategy for muck waste management that will contribute to a circular economy. A comparison between the traditional governance process and platform governance of muck truck management is made by using Petri-net. Nanjing’s muck smart supervision platform is used as a case study to assess effectiveness of the platform governance mode. Results from Petri-net simulation modeling software reveal that the platform governance mode is more effective than the traditional mode. Based on the case study of Nanjing’s muck smart supervision platform, it is found that the success of Nanjing's muck waste management can be attributed to the platform governance mode. This means that the platform management approach can contribute to the sustainability of muck waste governance. It is feasible to utilize the platform governance mode for muck waste as an integrated and effective management mode for current practices of muck waste management and resource recovery in China. The platform governance mode can signi�cantly improve the e�ciency of muck waste management and provide economic and environmental bene�ts as part of a circular economy.
THE EFFECT OF MACROECONOMIC VARIABLES ON FISCAL SUSTAINABILITY IN INDONESIA, PERIOD 2004Q1-2018Q4

Abstract Fiscal sustainability illustrates the condition of a healthy government budget which can finance government spending without increasing debt supply. The purpose of this study is to analyze the impact of macroeconomic variables on fiscal sustainability which in this study fiscal sustainability is proxied as a government budget deficit. The data used in this study is the 2004Q1-2018Q4 time series data using the Vector Error Correction Model (VECM). The results showed that fiscal conditions in Indonesia are sustainable and macroeconomic variables such as domestic debt andinflation has a positive effect on increasing the government budget deficit. Whereas the variable state revenues and foreign debt negatively affect the government budget deficit.Keywords : Fiscal Sustainability, Government Budget Deficit, Domestic Debt, Foreign Debt.
Diagnosis and treatment of basal cell carcinoma European consensus-based interdisciplinary guidelines Association of Dermato-Oncology (EADO), European Organization for Research and Treatment of Cancer

Basal cell carcinoma (BCC) is the most common malignant tumor in white populations. Multidisciplinary experts from the European Dermatology Forum, the European Association of Dermato-Oncology and the European Organization of Research and Treatment of Cancer collaborated to develop recommendations on diagnosis and treatment of BCC. A new classification into “easy-to-treat” (common) BCC and “difficult-to-treat” BCC is proposed. Diagnosis is based on clinico-dermatoscopic features for “easy-to-treat” BCCs. Histopathological confirmation is mandatory in ambiguous lesions and in BCCs located in high-risk areas. The first line treatment of “easy-to-treat” BCC is complete surgery. Microscopically controlled surgery shall be offered in high-risk BCC, in recurrent BCC and in critical anatomical sites. Topical therapies (imiquimod 5%, 5% fluorouracil) and destructive approaches (curettage, electrocautery, cryotherapy, laser ablation) should be considered in patients with low-risk superficial BCC. Photodynamic therapy is an effective treatment for superficial BCC and thin nodular BCC. The therapy for a “difficult-to-treat” BCC should preferentially be discussed by a multidisciplinary tumor board. Hedgehog inhibitors, vismodegib or sonidegib, should be offered to patients with locally advanced and metastatic BCC. Immunotherapy with anti-PD1 antibodies is a promising therapeutic option, currently being investigated in clinical trials. Radiotherapy represents a valid alternative to surgery for BCC on the face especially in elderly patients. In patients with nevoid basal cell carcinoma syndrome (NBCCS), close surveillance and regular skin examinations are required to diagnose and treat BCCs at early stage. Long-term follow-up is recommended in patients with high-risk BCC subtypes, high-risk sites, multiple BCCs and NBCCS.
Buprenorfina-naloxona en el tratamiento de la dependencia a opiáceos

En los últimos diez años la buprenorfina ha aumentado su disponibilidad en Europa como alternativa a la metadona en el tratamiento de la dependencia a opiáceos. La buprenorfina es un opiáceo sintético con actividad agonista parcial utilizado en el tratamiento de sustitución de la dependencia a opiáceos. Diversos estudios han demostrado que posee una eficacia superior a placebo y similar a metadona.
Weathering the storm : the Mersey Docks financial crisis 1970-74

Today the port of Liverpool is one of Britain's most successful ports and the Mersey Docks and Harbour Company , owning ports in the South East of England as well as Liverpool, is strong and thriving. Yet it did not always seem that this would be so. In "Weathering the Storm", Anthony Lynch records the financial crisis in the Mersey Docks during the period 1970-74 ans explains how it was resolved. He sets out claerly and concisely the events and the financial solutions in the 4-year struggle to establish a secure future. This is not a general history of the modern period of the port of Liverpool, dealing only with the financial crisis, but it does offer wider insights and provides a glimpse towards a future success that was unimaginable in 1970.
THE INFLUENCE OF BCG VACCINE TO THE CALVES‘S SKIN AFTER ADMINISTRATION

Annotation The article presents the results of a study on calves after application of BCG vaccine. in the experiment, the calves of the Kazakh white breeds, 1-2 months of age. Using electron microscopy allowed establishing pronounced ultrastructural changes in the organism of calves immunized with BCG vaccine. They are characterized by: the destruction of the muscle fibers of the dermis and the appearance of necrotic detritus; macrophage reaction followed fibrotization tissue at the injection site; destruction of mitochondria in hepatocytes and epithelial tubules uriniparous; swelling of podocytes in renal vascular glomeruli. and also develop less serious violations: serous edema, partial fragmentation of striated fibers in the tissue at the site of these biologics, swelling of mitochondria with cristae fuzzy pattern in epithelial cells of the liver and kidneys.
Long-term impact of gastropexy on use of acid-reducing medication, second operations for gastroesophageal re�ux and subjective re�ux symptoms after sleeve gastrectomy

Background/Objectives Gastopexy (G) has been introduced as a surgical technique to reduce gastroesophageal re�ux disease (GERD) in patients undergoing sleeve gastrectomy (SG). We aimed to determine whether adding G to SG improves use of acid reducing medication (ARM), second operations for GERD, epigastric pain or heartburn after surgery. Subjects/Methods Patients undergoing SG at two Norwegian hospitals were included consecutively from 2011 to 2015. Data was collected prospectively up to 7 years after surgery. GERD was de�ned by use of ARM on a regular basis and epigastric pain and heartburn by questions derived from the Rome II classi�cation of functional gastrointestinal disorders. G was de�ned as suturing the gastrocolic ligament to the staple line. Patients undergoing SG only (NG group) were compared to those with additional G (G group) by mixed effect models
El Nio flood deposits at Batn Grande, northern Peru

Recent construction of a 10 × 3 irrigation canal across the Batan Grande–Poma archaeological complex of northern Peru provided an opportunity for inspection of soil profiles and detailed sampling along a five km transect bisecting an important concentration of ceremonial structures built during the past 3000+ years. From laboratory analysis of 80 soil samples we conclude no long-term irrigation agriculture was practiced in this area and it was unimportant as a resource base. Stratigraphic studies indicate few sediments survive from the 1925 El Nino event, but a massive bed attributable to prehistoric slack-water flood sediments has been identified and can be bracketed between ca. A. D. 650–1000 by associated diagnostic funerary ceramics. Other flood deposits representing the same or different events are described, but we conclude intervalley correlations will be difficult until more precise dating methods are available.
Etude de la modification des propriétés rhéologiques linéaires et non linéaires par ingénierie moléculaire : Vers le contrôle des propriétés adhésives de matériaux autocollants

Dans ce travail, nous avons souhaite etudier l'impact de la structure sur les proprietes adhesives enexplorant differentes architectures dont des etoiles a trois branches de longueur importante, elles-memesramifiees par des branches longues, synthetisees en plusieurs etapes par polymerisation radicalaire controlee.Nous avons egalement etudie des polymeres lineaires et des copolymeres a bloc. Ils sont en particulier constituesde poly(acrylate de n-butyle) naturellement collant a temperature ambiante, permettant ainsi une etude desproprietes adhesives sans formulation. Toutefois, la masse molaire entre enchevetrements elevee du PnBA s'estaveree etre un frein car les techniques de polymerisation choisies n’ont pas permis la synthese de massesmolaires suffisamment elevees pour obtenir le comportement typique d'une etoile possedant les niveaux decomplaisance vises. Etant donne qu'une grande part de l'energie dissipee lors du decollement est due a laformation et a l'extension d'une structure fibrillaire, nous avons propose d'explorer les proprietes rheologiquesdans le domaine lineaire mais egalement aux grandes deformations par des tests d'elongation. Par ailleurs, destests de tack avec une visualisation par camera rapide des phenomenes ayant lieu au sein des echantillons durantle decollement ont ete mis en place. Nous avons confronte les proprietes rheologiques et les performancesadhesives pour toutes les structures analysees. Des melanges de polymeres lineaires avec une tres haute massemolaire peuvent presenter du rheodurcissement, et nous avons confirme que les conditions d'apparition sontlimitees si la polymolecularite devient trop importante. Pour les polymeres en etoile, nous avons plusparticulierement analyse l’importance de la complaisance d’equilibre sur les performances adhesives. Lescopolymeres a bloc presentant une tenue suffisante pour etre analyses en elongation ont montre un fortrheodurcissement, mais une propagation de fissure interfaciale lors des tests de tack, par manque dedeformabilite, empechant de beneficier de l'apport du rheodurcissement.
Finite element analysis of the effect of loading curve shape on brain injury predictors

Prediction of traumatic and mild traumatic brain injury is an important factor in 13 managing their prevention. Currently, the prediction of these injuries is limited to 14 peak linear and angular acceleration loading curves derived from laboratory 15 reconstructions. However it remains unclear as to what aspect of these loading 16 curves contributes to brain tissue damage. This research will use the University 17 College Dublin Brain Trauma Model (UCDBTM) to analyze three distinct 18 loading curve shapes meant to represent different helmet loading scenarios. The 19 loading curves were applied independently in each axis of linear and angular 20 acceleration, and their effect on currently used predictors of TBI and mTBI. 21 Loading curve shape A had a late time to peak, B an early time to peak and C had 22 a consistent plateau. The areas for all three loading curve shapes were identical. 23 The results indicate that loading curve A produced consistently higher maximum 24 principal strains and Von Mises Stress than the other two loading curve types. 25 Loading curve C consistently produced the lowest values, with loading curve B 26 being lowest in only 2 cases. The areas of peak Von Mises Stress and Principal 27 strain also varied depending on loading curve shape and acceleration input.
Adventurer: Exploration with BiGAN for Deep Reinforcement Learning

Recent developments in deep reinforcement learning have been very successful in learning complex, previously intractable problems. Sample efficiency and local optimality, however, remain significant challenges. To address these challenges, novelty-driven exploration strategies have emerged and shown promising potential. Unfortunately, no single algo-rithm outperforms all others in all tasks and most of them struggle with tasks with high-dimensional and complex observations. In this work, we propose Adventurer, a novelty-driven exploration algorithm that is based on Bidirectional Generative Adversarial Networks (BiGAN), where BiGAN is trained to estimate state novelty. Intuitively, a generator that has been trained on the distribution of visited states should only be able to generate a state coming from the distribution of visited states. As a result, novel states using the generator to reconstruct input states from certain latent representations would lead to larger reconstruction errors. We show that BiGAN performs well in estimating state novelty for complex observations. This novelty estimation method can be combined with intrinsic-reward-based exploration. Our empirical results show that Adventurer produces competitive results on a range of popular benchmark tasks, including continuous robotic manipulation tasks (e.g. Mujoco robotics) and high-dimensional image-based tasks (e.g. Atari games).
POLICY EVALUATION AND EMPIRICAL GROWTH RESEARCH

This paper explores the implications of the vast body of studies of cross-country growth determinants for the evaluation of alternative policies. Empirical growth studies have experienced a remarkable flowering in the last fifteen years, and innumerable insights have unquestionably been uncovered concerning similarities and differences in the growth experiences of various groups of countries. This empirical work was stimulated by—and, in turn, has been an essential complement to—the revival of growth theory initiated by the seminal papers of Lucas (1988) and Romer (1986). It constitutes one of the great successes of recent macroeconomic research. In addition to identifying empirical regularities in growth, the empirical literature makes numerous claims concerning the impacts of alternative policies on the growth trajectories of different countries. This focus on policy implications is natural given the huge welfare implications of changes in a country’s growth rate. A recent graduate-level textbook remarks
Paraneoplastische neurologische Syndrome

Der vorliegende Artikel vermittelt einen Überblick über Epidemiologie, Pathophysiologie, Klinik, Diagnostik, Therapie und Verlauf der paraneoplastischen neurologischen Syndrome. Darüber hinaus werden die klassischen paraneoplastischen neurologischen Erkrankungen mit ihren assoziierten Tumoren und spezifischen onkoneuronalen Antikörpern ausführlicher dargestellt. Ziel ist es, fundierte Grundlagen zu vermitteln, um PNS klinisch zu erkennen, ihre rationelle Diagnostik zu planen und die Prinzipien der Behandlung zu kennen.
Ischämischer Schlaganfall: geringere Thrombuslast – besseres Ergebnis

Die Revaskularisierung der betroffenen Gefäße ist bei ischämischem Schlaganfall die wichtigste Maßnahme. Dabei scheint heute die endovaskuläre Behandlung der traditionellen Lysetherapie überlegen, wie eine Reihe von randomisierten Studien gezeigt hat. Trotzdem erlangen viele Patienten ihre funktionelle Unabhängigkeit nicht zurück. Inwieweit die Thrombuslast die Ergebnisse beeinflusst, haben niederländische Mediziner untersucht.
Marine and Coastal Fisheries: Dynamics, Management, and Ecosystem Science

Abstract Spotted Seatrout Cynoscionnebulosus is the most highly sought after recreational species along the U.S. Gulf coast.However, movement information for this economically and ecologically important species is currently limited to datafrom mark–recapture studies. We used remote acoustic telemetry, a high-resolution, ﬁsheries-independent technique,to examine the residency of adult Spotted Seatrout ( n = 172) in a Louisiana estuary, Calcasieu Lake ( ∼ 300 km 2 ). An estuarine-wide array of 60 receivers was deployed for a 2.5-year period (May 2007–October 2009) to detect andquantify how long ﬁsh were present in the estuary and determine the proportion of ﬁsh that emigrated from thesystem. We then determined how these metrics (detection period and emigration) were related to ﬁsh size, sex, andseason of release. Emigration was highly seasonal and occurred exclusively during late spring and summer whenwatertemperaturesexceeded24 ◦ C.Surprisingly,maleSpottedSeatrout,regardlessoftheirsize,weremorelikelythanfemales to “permanently” emigrate from the estuary (i.e., not return within the 1-year battery life of transmitters)as evidenced by their shorter mean detection periods (males
PTPN3 inhibition contributes to the activation of the dendritic cell function to augment the effect of cancer immunotherapy

In a previous study, protein tyrosine phosphatase non-receptor type (PTPN) 3 was identi�ed as an immune checkpoint molecule in lymphocytes, and its potential as a novel therapeutic target for cancer immunotherapy was anticipated. However, evaluation of dendritic cell (DC) function as antigen-presenting cells is critical for development of immunotherapy. This study aimed to analyze the biological effect of PTPN3 on DCs induced from human peripheral blood monocytes obtained from healthy individuals. PTPN3 knockdown by siRNA signi�cantly increased the number of DCs, the expression of CD80 and CCR7, and the production of IL-12p40/p70 in mature DCs. Using an HLA-A24-restricted DC and human lung squamous cell carcinoma cell cytotoxic assay, PTPN3 inhibition in mature DCs induced cytotoxic T lymphocytes with increased production of INF-γ and granzyme B and enhanced cytotoxicity against cancer cells and migration to cancer. Furthermore, PTPN3 inhibition activated the MAPK pathway in DCs. These �ndings suggest that PTPN3 inhibition can contribute to the development of novel cancer immunotherapies that not only activate lymphocytes, as previously reported, but also activate DCs.
The influence of multiple indices of socioeconomic disadvantage across the adult life course on the metabolic syndrome: the Vietnam Experience Study

Background : Few studies have explored the relationship between individual and combined multiple indicators of socio-economic status across the life course and the metabolic syndrome, or attempted to understand the mechanisms underlying any associations. The present study examined the associations between four indicators of socio-economic status, individually and in combination, and metabolic syndrome risk in a study of male US veterans, and examined the influence of health behaviours, intelligence, and psychological distress on these associations. Methods : Participants (N = 4253) were drawn from the Vietnam Experience Study. From military service files, telephone interviews, and a medical examination, occupational, socio-demographic, health behaviour, intelligence, psychological, and health data were collected. The four indices of socio-economic status were: education achieved, early adulthood income, household income in midlife, and occupational prestige in midlife. Metabolic syndrome was diagnosed from: body mass index; fasting blood glucose or a diagnosis of diabetes; blood pressure, a diagnosis of hypertension, or taking anti-hypertensives; high density lipoprotein cholesterol; and triglyceride levels. Results : In models that adjusted for age, men in the lower two groups on the combined measure of socio-economic status experienced a higher risk of metabolic syndrome. This association was accounted for mainly by education achieved, household income in midlife, and occupational prestige in midlife. Intelligence appeared to explain much of this association. Conclusions : Combined socio-economic status measures across the life course were related to metabolic syndrome but in a threshold rather than dose-response manner. Intelligence appeared to mediate this relationship.
Fishery and certain biological aspects of Stolephorus devisi (Whitley) at Cochin, west coast of India

Stolephorus devisi is the most abundant of the six white bait species landed at Cochin and contributes upto 55.8% of the white bait catch. Peak landings were noticed during April•May and November•December. The individuals in the landings ranged from 50 to 98 rrun in total length. The species attained a total length of 88mm at the end of frrst (ear. The length-weight relationship was found to be W=O.()()()()1236356 L2.98 for males and W=O.OOOOO5873346 L3.O for females. The length at first maturity for the species was 56 mm.
Mobile-Internet-Based Healthcare, Public Safety and Home Welfare Services

Home assistant services have been growing up during the past years, and more elderly suffer from chronic diseases. This paper introduces the feasibility and beneﬁts of health care, public safety and home welfare services for elderly monitoring using mobile internet network. Two key human-device issues are analyzed in the paper: usability and user acceptance. Moreover, the services are studied from the Chinese perspective.
Experience From Australian Stroke Center Cost-Effectiveness of Thrombolysis Within 4.5 Hours of Acute Ischemic Stroke :

of stroke onset have lower healthcare costs than those not. We aim to perform cost-effectiveness analysis of intravenous tPA in an Australian setting. Methods —Data on clinical outcomes and costs were derived for 378 patients who received intravenous tPA within 4.5 hours of stroke onset at Royal Melbourne Hospital (Australia) between January 2003 and December 2011. To simulate clinical outcomes and costs for a hypothetical control group assumed not to have received tPA, we applied efficacy data from a meta-analysis of randomized trials to outcomes observed in the tPA group. During a 1-year time-horizon, net costs, years of life lived, and quality-adjusted life-years were compared and incremental cost-effectiveness ratios derived for tPA versus no tPA. Results —In the study population, mean (SD) age was 68.2 (13.5) years and 206 (54.5%) were men. Median National Institutes of Health Stroke Scale score (interquartile range) at presentation was 12.5 (8–18). Compared with no tPA, we estimated that tPA would result in 0.02 life-years and 0.04 quality-adjusted life-years saved per person >1 year. The net cost of tPA was AUD $55.61 per patient. The incremental cost-effectiveness ratios were AUD $2377 per life-year saved and AUD $1478 per quality-adjusted life-years saved. Because the costs of tPA are incurred only once, the incremental cost-effectiveness ratios would decrease with increasing time-horizon. Uncertainty analyses indicated the results to be robust. Conclusions —Intravenous tPA within 4.5 hours represents a cost-effective intervention for acute ischemic stroke. ( Stroke . 2013;44:00-00.)