Miracle-dz/UniFAR-FTUs huggingface dataset:
Mathematical Modeling of Static Data Attribute Encryption Based on Big Data Technology

Attribute encryption is an effective one to many network communication technologies, which supports flexible access control strategies and is very suitable for fine-grained access control in large-scale information systems. In order to improve the attributes of static data, encryption technology can provide a reliable technical guarantee for network security. This paper presents a mathematical modeling method of static data attribute encryption based on big data technology. The big data redundancy elimination algorithm based on similarity calculation is analyzed. By using static data attribute encryption based on big data technology, the length of encrypted data packets will not increase, and partial redundancy of fragments can be eliminated, which can greatly improve the efficiency of the system. The attribute-based encryption mechanism uses attributes as public keys, and the decryption user is a group; so, the encryption efficiency is very high. It can realize efficient encryption and decryption, as well as flexible access control based on user attributes. This scheme can reflect the importance of attributes; so, it is more practical.
Physical Exercise as Treatment for Type 2 Diabetes Distal Symmetric Polyneuropathy: A Systematic Review of Randomized and Controlled Studies

Pharmaceuticals targeting the pathogenesis of diabetic distal symmetric polyneuropathy have all failed in clinical trials, limiting recourse to palliative treatments. The American Diabetes Association regards the effectiveness of glycemic control and lifestyle modification therapies on diabetic neuropathies as inconclusive. The objective of this research was to determine if and how physical exercise influences distal symmetric polyneuropathic severity in type 2 diabetes patients. Embase, MEDLINE, and Google Scholar were searched to collect randomized and controlled studies published between January 1, 2012 and April 20, 2020. Titles had to mention diabetes, physical exercise of any type or lifestyle interventions in general, and neuropathy. Abstracts had to indicate satisfaction of PICOS criteria, whereas full-text reviews had to be fully confirmatory. Extracted data was thematically synthesized based primarily on relationships between exercise interventions and effects on distal symmetric polyneuropathic severity outcomes in type 2 diabetes patients. Qualitative analysis scoring criteria objectively mirrored PICO except for the bias and limitation score component, which assessed common markers of validity for randomized trials (as specified in the PRISMA statement). Database searches yielded 379 unique records, 15 of which passed eligibility screening. Thematic synthesis supported exercise as an ameliorative treatment of type 2 diabetes distal symmetric polyneuropathy through improved Michigan Diabetic Neuropathy Scores and increased sural sensory nerve conduction velocity, though efficacy may be limited by neuropathic
Different Approaches to Errors in Classroom Discussions: The Case of Algebraic Inequalities

Abstract The paper describes a study that examined the impact of two teaching approaches “focus on correctness” and “discuss errors” on secondary students’ solutions to algebraic inequalities. Two groups of 10th graders were taught by two experienced teachers, Corry and Era, who followed their different didactical beliefs about the use of errors in classroom discussions. Both groups studied according to the same curriculum during an identical time frame and answered the same problem-sets on the same days. We found that students in the "discuss errors" group performed significantly better in solving most inequalities. We believe that additional and more extensive studies, examining this issue are needed.
Post Chikungunya Fever and Post COVID-19 Bilateral Pedal Edema: A Case Report

An 86-year-old male presented with fever and joint pain for seven days. Clinical features were suggestive of chikungunya fever, but reverse transcription-polymerase chain reaction (RT-PCR) was negative. After ruling out the differentials, the patient was clinically diagnosed with chikungunya fever. Chikungunya IgG antibody was positive two months after the onset of symptoms. He had a history of asymptomatic coronavirus disease (COVID-19) infection two months ago. About 20 days after his first symptom, he developed bipedal edema, refractory to diuretics. All other causes of pedal edema, including heart failure, renal failure, and liver failure, were ruled out. The bipedal edema was managed conservatively with compression bandages. Only a few case reports and studies on limb edema as a symptom post chikungunya fever have been published up to this point. Furthermore, it is difficult to say whether his COVID-19 infection is linked to the edema.
Enhanced visible-light photocatalytic activity of rGO-ZnO composite thin films prepared by SILAR method

ABSTRACT This study reported the first-time preparation of reduced graphene oxide (rGO) and zinc oxide (ZnO) composite (rGO-ZnO) thin films through successive ionic layer adsorption and reaction (SILAR) method. The effects of rGO and heat treatment on the structural, morphological, chemical, optical, vibrational and photocatalytic properties of composite films were investigated. The structural results showed that ZnO and rGO-ZnO thin films could be obtained without heat treatment. The rGO-ZnO composite showed improved crystallinity and homogeneity compared to ZnO, with formation of flower-like structures. The presence of graphene derivatives in the composite films was validated using Raman spectroscopy. Chemical composition analysis showed an increase in the carbon content in rGO-ZnO composite. Optical transmittance in the visible range was reduced from 90% for ZnO to 51% for rGO-ZnO. Moreover, the bandgap energy of ZnO decreased from 3.33 to 3.04 eV with the presence of rGO and heat treatment. The rGO-ZnO composite thin films exhibit enhanced visible-light photocatalytic discoloration of Orange G dye, which is attributed to bandgap narrowing with improved visible light response and charge separation. The approach described here provides a simple and efficient way to synthesise rGO-ZnO composite thin films with potential applications for a wide range of environmental issues.
Nutritional profile of climbing perch (Anabas testudineus Bloch, 1792) muscle tissue with emphasis on seasonal variations

Nutritional profile of Climbing Perch ( Anabas testudineus Bloch, 1792) muscle tissue were analyzed with emphasis on seasonal variations. Climbing Perch muscle tissue had high lipid content, constituting about 12.87%. The mean value of protein, moisture and ash were found to be 15.46, 68.86 and 1.25%, respectively. Highest values were observed in the month of March and April for protein (17.02%) and lipid (14.06%), respectively, while lowest values were in the month of July for both protein (13.02%) and lipid (11.08%). Highest and lowest values for water content were noticed in the month of July (73.37%) and March (66.91%). Protein ( P <0.01) and lipid ( P <0.01) content showed a negative correlation with moisture content within the muscle tissue. Additionally, between protein and lipid a positive relation was observed ( P <0.01). Ash content showed no significant correlation with protein, lipid or moisture content in the muscle tissue and its maximum value was noticed in the month of March (1.75%). The results suggested that the proximate composition of fish muscle tissue significantly varies during different seasons. The present studies thus provide information on variation in proximate composition of the Climbing Perch with seasons which is useful for the processing industry.
Development of "virtual patient" model for simulation of solute and fluid transport during dialysis

Optimization of dialysis needs methods for quantitative assessment of fluid and solutes transport in body compartments and solute and fluid exchange between body and dialysate. A mathematical model describing the dynamics of these quantities during dialysis is presented. This model is first and foremost based on the existing models, but also includes some new solutions. All parts were combined and extended by the detailed descriptions of selected aspects. The “virtual patient” model was applied to simulate and test different methods of treatment and their influence on the condition of the patient. The purpose of this model is to serve as a decision support system for selection of “optimal” treatment options for particular patient.
Atypical palmoplantar lesion in relapsed advanced latent syphilis with HIV co-infection

Syphilis is a systemic infection caused by Treponema pallidum subspecies pallidum , which has a major and various manifestations on the skin (the great imitator). Its prevalence is frequently associated with Human Immunodeficiency Virus (HIV) prevalence. Atypical and aggressive presentation of syphilis is more commonly found in persons with syphilis and coinfection of HIV. We report a case of a 30-year-old male with erythematous plaques and desquamation on his palms and soles with neither pain nor pruritus, and also Beau’s line on the hand and toe nails. HIV infection was detected. The diagnosis of the patient was relapse late latent syphilis with HIV co-infection. The diagnosis of syphilis was established based on clinical and serological testing. The clinical manifestations of syphilis in immunosuppressed patients are often atypical. In order to treat, the patient was prescribed with doxycycline 100 mg two times a day for a month and showed clinical improvement after three weeks course of medication. Serologic testing interpretation and treatment do not differ between syphilis patients with and without HIV coinfection.
Detection of HIV-1 Transmission Clusters from Dried Blood Spots within a Universal Test-and-Treat Trial in East Africa

The Sustainable East Africa Research in Community Health (SEARCH) trial was a universal test-and-treat (UTT) trial in rural Uganda and Kenya, aiming to lower regional HIV-1 incidence. Here, we quantify breakthrough HIV-1 transmissions occurring during the trial from population-based, dried blood spot samples. Between 2013 and 2017, we obtained 549 gag and 488 pol HIV-1 consensus sequences from 745 participants: 469 participants infected prior to trial commencement and 276 SEARCH-incident infections. Putative transmission clusters, with a 1.5% pairwise genetic distance threshold, were inferred from maximum likelihood phylogenies; clusters arising after the start of SEARCH were identified with Bayesian time-calibrated phylogenies. Our phylodynamic approach identified nine clusters arising after the SEARCH start date: eight pairs and one triplet, representing mostly opposite-gender linked (6/9), within-community transmissions (7/9). Two clusters contained individuals with non-nucleoside reverse transcriptase inhibitor (NNRTI) resistance, both linked to intervention communities. The identification of SEARCH-incident, within-community transmissions reveals the role of unsuppressed individuals in sustaining the epidemic in both arms of a UTT trial setting. The presence of transmitted NNRTI resistance, implying treatment failure to the efavirenz-based antiretroviral therapy (ART) used during SEARCH, highlights the need to improve delivery and adherence to up-to-date ART recommendations, to halt HIV-1 transmission.
Detecting Loaded Trajectories for Hazardous Chemicals Transportation

Hazardous chemicals transportation (HCT) brings significant financial, environmental, and health-related risks. It is imperative that a robust regulatory system is in place to reduce the risk of accidents occurring while such hazardous chemicals are being transported. Governments around the world use GPS sensors to monitor the raw trajectories of HCT trucks, but they have difficulty detecting the loaded trajectories, which is of utmost importance for the management of H CT processes. The loaded trajectory refers to the subtrajectory generated by tracking an HCT truck when it is loaded with hazardous chemical in an HCT process. The stay points in the raw trajectory provide some feasibility to detect the loaded trajectory as they reflect the potential loading and unloading actions of the HCT truck. However, directly using the stay points to detect the loaded trajectory usually leads to unsatisfactory results due to two chal-lenges: (1) complex staying scenarios, and (2) numerous loading and unloading locations. To tackle the challenges, we propose a LoadEd trAjectory Detectlon framework, called LEAD, to detect the loaded trajectory from the raw HCT trajectory accurately and efficiently. LEAD processes a raw trajectory into a set of candidate trajectories, encodes each candidate trajectory into a latent representation, and detects the loaded trajectory using the latent representations of candidate trajectories. Extensive experiments based on a real-world dataset from Nantong, China confirm the effectiveness of our framework. The results show that the detection accuracy of LEAD exceeds 83 % which outperforms competing baselines by over 42 %.
Evaluation of PepT1 (SLC15A1) Substrate Characteristics of Therapeutic Cyclic Peptides

The human peptide transporter hPepT1 (SLC15A1), physiologically transporting dipeptides and tripeptides generated during food digestion, also plays a role in the uptake of small bioactive peptides and peptide-like drugs. Moreover, it might be addressed in prodrug strategies of poorly absorbed drugs. We hypothesised that the cyclic drug peptides octreotide and pasireotide could be substrates of this transporter because their diameter can resemble the size of dipeptides or tripeptides due to their strong structural curvature and because they reach the systemic circulation in Beagle dogs. For investigating possible hPepT1 substrate characteristics, we generated and characterised a CHO-K1 cell line overexpressing SLC15A1 by transfection and selection via magnetic beads. Possible inhibition of the uptake of the prototypical substrate Gly-Sar by octreotide and pasireotide was screened, followed by quantifying the uptake of the cyclic peptides in cells overexpressing SLC15A1 compared with the parental cell line. Although inhibition of Gly-Sar uptake was observed, uptake of octreotide and pasireotide was not increased in SLC15A1 overexpressing cells, indicating a lack of transport by hPepT1. Our data clearly indicate that octreotide and pasireotide are nonsubstrate inhibitors of hPepT1 and that their oral bioavailability cannot be explained by absorption via hPepT1.
review on “pharmacological, phytochemical, and medicinal properties of rosmarinus officinalis (Rosemary)”

International use of natural medicinal drugs has been increasing in the last few centuries. In developing international locations, many people were using other natural remedies to meet their fitness care desires. On the opposite facet, developing countries had to make a bigger interest in medicinal herbs. The most vital difficulty in natural medicine is that their market is inadequate regulated, and very restricted statistics have been presented regarding the safety and efficacy of medicinal herbs. there's almost no side impact within the use of herbal merchandise. natural medicines provide harmless and efficient use.Rosemary consists huge form of phytochemicals along with the impact of dietary antioxidative and chemopreventive rosemary phytochemical on the feature of human drug efflux transporter Pglycoprotein and multidrug resistance protein 1 . The effect of natural phytochemical found in rosemary inclusive of carnosic acid , carnosol , rosemarinic acid , and ursolic acid and different many additives. Rosemary appears to boom blood circulation while applied to the scalp, which would possibly assist hair follicles develop. Rosemary extract may additionally help guard the pores and skin from solar harm.
Pengaruh Firm Performance Terhadap Intellectual Capital Disclosure

Intellectual capital is an intangible asset consisting of human resources (human capital), corporate organization (structural capital), and relational value (relational capital) that can increase the value of a company. The research objective is to obtain empirical facts about the effect of firm size, minority share, liquidity, profitability, leverage, asset turnover, and market to book value on intellectual capital disclosure. The research was conducted on companies listed on the Indonesia Stock Exchange in 2017-2021. The selected sample results contained 1,827 observational data. The information analysis procedure used is linear regression analysis. The results of the research prove that firm size has a positive effect on intellectual capital disclosure. Minority share, liquidity, profitability, leverage, asset turnover, and market to book value do not affect intellectual capital disclosure. Keywords: Intellectual Capital Disclosure; Firm Performance.
Using sport-based interventions for people with severe mental disorders: results from the European EASMH study

Abstract People with severe mental disorders report significantly poorer physical health and a higher mortality rate compared with the general population. Several interventions have been proposed in order to challenge this mortality gap, the promotion of physical activities represents one of the most important strategies. In fact, in people with severe mental disorders, physical activity can improve body composition, quality of life, personal functioning, self-esteem, cognition, and cardiorespiratory fitness, as well as reducing affective, psychotic and anxiety symptoms, cardiometabolic burden and increase the global recovery. While sport-based programs are consistently being proposed as an integral part of effective personalized treatment approaches for people with severe mental disorders, their routine implementation is hampered by poor working task integration among different professionals and the lack of training programmes for sport professionals focused on people with severe mental disorders. In this paper, we will: (a) review the efficacy of exercise/sport-based interventions for people with severe mental disorders; (b) describe the main difficulties in engaging patients with severe mental disorders in these interventions; and (c) report the results of the first study on the best practices available in Europe in the field of sport and mental health carried out in the context of the European Alliance for Sport and Mental Health (EASMH) project. According to the EASMH survey, sport-based psychosocial interventions are not frequently available in mental health services, with significant differences at the European level. In the near future, it would be advisable to promote the integration and collaboration between mental health professionals and sport professionals, in order to improve the dissemination and availability of sport-based interventions in routine clinical practice. The EASMH project aims to fill this gap by creating a network of collaborators, researchers and stakeholders with different backgrounds in order to improve the dissemination of sport-based rehabilitation interventions and by developing an innovative training programme for sport coaches in order to improve their skills in interacting and building an effective relationship with people with severe mental disorders.
3.10. X-ray constraints on accretion and starburst processes in galactic nuclei

Although the galaxies in our sample are heterogenous in their optical classifications (LLAGN: M51, NGC 3147, NGC 4258; LINER: NGC 3079, NGC 3310, NGC 3998, NGC 4579, NGC 4594; starburst: M82, NGC 253, NGC 3628, NGC 6946), they are fit well by a “canonical” spectrum with a hot, optically-thin thermal component with T ~ 8 × 10 6 K and an absorbed ( N H ~ 10 22 cm −2 ) power-law with an energy index α ~ 0.7–0.8. Both the “soft” component, most likely due to SN or superwind-heated ISM, and the “hard” power-law, most likely due to a micro-AGN and/or blackhole candidates, appear to be common in low-activity galaxies. If the soft component is associated with a superwind outflow, than ~ 10% of the X-ray emission is due to “swept-up” ISM rather than superwind emission. The abundance of Fe relative to α -process elements tends to be sub-solar, possibly due to dust-depletion and/or type-II SN enrichment. The lack of short-term variability in the hard component suggests that if it is due to an AGN, then the mode of accretion is probably fundamentally different from “normal” Seyfert galaxies.
Chronic stress-induced synaptic changes to corticotropin-releasing factor-signaling in the bed nucleus of the stria terminalis

The sexually dimorphic bed nucleus of the stria terminalis (BNST) is comprised of several distinct regions, some of which act as a hub for stress-induced changes in neural circuitry and behavior. In rodents, the anterodorsal BNST is especially affected by chronic exposure to stress, which results in alterations to the corticotropin-releasing factor (CRF)-signaling pathway, including CRF receptors and upstream regulators. Stress increases cellular excitability in BNST CRF+ neurons by potentiating miniature excitatory postsynaptic current (mEPSC) amplitude, altering the resting membrane potential, and diminishing M-currents (a voltage-gated K+ current that stabilizes membrane potential). Rodent anterodorsal and anterolateral BNST neurons are also critical regulators of behavior, including avoidance of aversive contexts and fear learning (especially that of sustained threats). These rodent behaviors are historically associated with anxiety. Furthermore, BNST is implicated in stress-related mood disorders, including anxiety and Post-Traumatic Stress Disorders in humans, and may be linked to sex differences found in mood disorders.
Enjoying My Time in the Animus: A Quantitative Survey on Perceived Realism and Enjoyment of Historical Video Games

This study investigates players’ perceived realism of historical video games. Perceived realism is understood as a multidimensional concept, going beyond the more traditional use of ‘realism’ in historical game studies, where it often refers to the plausibility or accuracy of historical reconstructions. The study further examines how perceived realism relates to players’ enjoyment of historical games. Specifically, this study analyses Assassin's Creed, Assassin's Creed Unity and Assassin's Creed Odyssey. Through an online survey among 1,317 respondents, this study found that the five-dimensional structure of perceived realism holds for historical games. The three games differed in their perceptions of social realism, perceptual pervasiveness, freedom of choice and enjoyment. Finally, perceptual pervasiveness and character involvement were identified as strong predictors of enjoyment in historical games. This study contributes towards further validation of the perceived realism scale across game genres and pleads for a systematic use of the multidimensional term ‘realism’ in historical game research.