Miracle-dz/UniFAR-FTUs huggingface dataset:
A pipelining strategy for accelerating convolution neural networks on ARM CPUs

Convolution is a primary operation in convolution neural networks. The speed of inference is mainly decided by the speed of the convolutional layer. Improving the performance of embedded processors makes it possible to process the inference on embedded devices. In this article, a pipelining strategy of single instruction and multiple data (SIMD) instructions is proposed to finely optimize the process of the 3 × 3 convolution on ARM‐based CPUs. We implement the SIMD group to improve the efficiency of the SIMD pipeline. A tiling method is exploited to increase data reuse during the process. An evaluation model is proposed to guide the design of the tiling method and register allocation. The speed of our implementation is 5.18 times of the GNU compiler collection compiled unoptimized version on RK3288. The effect of our optimizing method is measured by a performance profiling tool, the performance information suggests that the pipelining strategy has a significant effect for both normal and depthwise separable convolution. By implementing multithread processing, the speedup achieves 18.3 compared with the single thread unoptimized version.
Application of Mathematical Models in Drug Release Kinetics of Carbidopa and Levodopa ER Tablets

The aim of present work is to determine and analyse the kinetics of drug release from the matrix tablet by employing various mathematical models. A study was done with Carbidopa and Levodopa ER tablets, 50 mg/200 mg by employing wet granulation technique using Hydroxypropyl methylcellulose and Hydroxypropyl cellulose as matrix forming polymer. The in-vitro drug release profile was carried out in 0.1 N HCl (900 mL) using USP dissolution apparatus II (Paddle) at 50 rpm at an extended time period of 0.5, 0.75, 1, 1.5, 2, 2.5, 3 and 4 hours. The drug release data was obtained, quantitatively correlated and interpreted with various mathematical models viz. Zero order model, first order model, Higuchi model, Hixson-Crowell model and Korsmeyer-Peppas model and evaluated to understand the kinetics of drug release. The criterion for the most suitable model was based on the high degree of coefficient of correlation of drug release profile of Carbidopa Levodopa ER Tablet. Hence, finally concluded as the drug release pattern of Carbidopa Levodopa ER Tablets, 50 mg/200 mg was best fitted with Higuchi square root model and follows Higuchi drug release kinetics which is diffusion controlled.
Educação no estado do Ceará : análises utilizando o método do controle sintético

Este artigo avalia o impacto da gestão governamental do estado do Ceará nos indicadores educacionais, de cunho quantitativo e qualitativo, referentes ao ensino médio, no período de 2007 a 2014. Para tanto, utilizou-se o método de controle sintético. Uma análise descritiva mostrou uma evolução contínua do estado do Ceará, permanecendo acima da média da região Nordeste. O estado, a partir de 2009, ultrapassa a média nacional, permanecendo acima até o fim do período considerado. Na abordagem qualitativa, destaca-se o rápido crescimento entre 2011 e 2014, de modo que o Ceará, anteriormente abaixo, acompanha o desempenho nacional. Em suma, a partir dos resultados, conclui-se que a intervenção analisada, a gestão do governo do estado do Ceará de 2007 a 2014, apresentou bom rendimento na educação, tanto quantitativamente quanto qualitativamente.
A Practical Approach for Picking Items in an Online Shopping Warehouse

Commercially viable automated picking in unstructured environments by a robot arm remains a difficult challenge. The problem of robot grasp planning has long been around but the existing solutions tend to be limited when it comes to deploy them in open-ended realistic scenarios. Practical picking systems are called for that can handle the different properties of the objects to be manipulated, as well as the problems arising from occlusions and constrained accessibility. This paper presents a practical solution to the problem of robot picking in an online shopping warehouse by means of a novel approach that integrates a carefully selected method with a new strategy, the centroid normal approach (CNA), on a cost-effective dual-arm robotic system with two grippers specifically designed for this purpose: a two-finger gripper and a vacuum gripper. Objects identified in the scene point cloud are matched to the grasping techniques and grippers to maximize success. Extensive experimentation provides clues as to what are the reasons for success and failure. We chose as benchmark the scenario proposed by the 2017 Amazon Robotics Challenge, since it represents a realistic description of a retail shopping warehouse case; it includes many challenging constraints, such as a wide variety of different product items with a diversity of properties, which are also presented with restricted visibility and accessibility.
Inverse Association Between Age and Risk of Lymph Node Metastasis in Patients With Early Gastric Cancer: A Surveillance, Epidemiology, and End Results Analysis

Background: Recent studies have shown that young patients with gastric cancer (GC) are at a more advanced stage and have poor survival, but the cause is still unclear. And the prognosis of GC is closely related to Lymph node metastasis (LNM). It has been reported that age and LNM of superficial colorectal cancer are inversely proportional, but the relationship between age and prognosis in early gastric cancer (EGC) is currently unclear. Therefore, we aimed to study the relationship between age and the risk of LNM in EGC.Materials and Methods: We screened out patients with EGC who underwent surgery from the SEER research database from 1975 to 2016, and retrospectively analyzed the proportion of LNM in different age groups. The correlation between age and LNM was examined using univariate analysis and multivariate logistic regression analysis.Results: We included 9231 patients with EGC, and divided into 18-39 years old (2.3%), 40-49 (6.1%), 50-59 years old (15.7%), 60-69 years old (24.8%), 70-79 years old (27.2%) and ≥89 years old (23.9%) age group, and the proportions of lymph node metastasis were 20.3%, 23.3%, 21.0%, 19.8%, 18.1%, and 13.2 %. We found that as the age increases, the risk of LNM and postoperative survival time of EGC patients decrease (p<0.001). Conclusions: This study found that age in patients with EGC was inversely related to the risk of LNM, and positively correlated with postoperative survival. For older patients with EGC, endoscopic treatment is more appropriate. For young patients with EGC, LNM should be considered when choosing endoscopic treatment.
Functional fermented carob milk: Probiotic variability and polyphenolic profile

This study aimed to develop a synbiotic fermented milk with 4% carob powder (CB) as a functional ingredient and using Lactobacillus brevis as a new isolated probiotics strain. Physicochemical characteristics, probiotic viability, total phenolic content (TPC) and antioxidant capacity, antibacterial activity as well as the hypoglycemia activity of carob fermented milk were measured during a cold storage and gastro-intestinal digestion. CB addition to fermented milk improved the growth of Lactobacillus brevis and maintained their viability during the storage period (8 log CFU/g) and after digestion (7 log CFU/g). Carob fermented milk displayed higher TPC and higher antioxidant capacity during the storage. The digestion resulted in the release of bioaccessible phenolics where gallic acid (441%) and (+)-catechin (486%) were the most quantified phenolic compounds; thus, the inhibition of α-amylase (52%), α-glucosidase (37%) activity and higher antibacterial potential. These results demonstrate the potentials of carob fermented milk to be an important source of viable probiotics and bioaccessible polyphenols.
Antibacterial and Antioxidant activity of Benincasa hispida using Hydrogen peroxide scavenging model

The seeds of Benincasa hispida commonly known as ash gourd belonging to Cucurbitaceae family is employed as a main ingredient in kusmanda lehyam in Ayurvedic system of medicine. The seeds of Benincasa hispida mashed with milk or the various preparations from the pulp of fruit in the form of sweetmeats, like Kusmanda paka and petha are commonly used as a general tonic, aphrodisiac, rejuvenative and also a brain tonic. The plant of Benincasa hispida was collected from (Central Council for Research in Ayurveda and Siddha, Dept. of ayush, Ministry of Health and F.W, Govt. of India New Delhi) Govt. Central Pharmacy Annex, Ashoka Pillar, Jayanagar Bangalore. The extracts were subjected to Antioxidant activity by In hydrogen peroxide-scavenging model, model acetone extract showed scavenging (80.1%) of hydrogen peroxide and chloroform extract showed ( 79%) in comparison with ascorbic acid ( 94.5% ). Antioxidant activity was carried out for extract (acetone, chloroform, and aqueous extracts) with Hydrogen peroxide-scavenging model. Acetonic extract showed more scavenging (80.1%) of Benincasa hispida and least scavenging was done by aqueous extract of (43%). After comparison with the standard drug (Ascorbic acid) showed (94.5%). From this it was conclused that acetone extract of Benincasa hispida showed high scavenging activity. Conclusively, the result revealed that Benincasa hispida seeds has antimicrobial activity and antioxidant activity which may be due to the presence of alkaloids, phenolic compounds, flavonoids constituents present in the sample.
Plant dispersal syndromes are unreliable, especially for predicting zoochory and long‐distance dispersal

traits and the frequency and effectiveness of different dispersal mechanisms (paying attention to unexpected vectors). Acknowledging the broad role of non-frugivores in facilitating LDD is crucial to improve predictions of the consequences of global change, such as how plant distributions respond to climate change, and how alien plants spread. Networks of dispersal interactions between these vertebrates and plants are a vital but understudied part of the Web of Life.
Why and when do employees become more proactive under humble leaders? The roles of psychological need satisfaction and Chinese traditionality

PurposeDrawing on self-determination theory, this study explored how leader humility affected employees' proactive behavior through satisfying their psychological needs for autonomy, competence and relatedness. Furthermore, based on a contingency view, this paper suggested Chinese traditionality as a significant boundary condition for the effects of leader humility.Design/methodology/approachData were collected from 465 employees and 111 direct supervisors in China using a three-wave, two-source design. Hierarchical regression analyses and Hayes' PROCESS macro were applied to test the hypotheses.FindingsThe results indicated that leader humility positively affected employee proactive behavior through the mediating mechanisms of psychological need satisfaction (i.e. autonomy, competence and relatedness). Furthermore, these positive effects were stronger among employees with lower Chinese traditionality beliefs.Originality/valueAlthough prior research has examined the relationship between leadership and proactive behavior, most extant studies have focused on “top-down” leadership approaches, ignoring the effect of leader humility. Drawing on self-determination theory, the present study makes contributions to both the leader humility research and proactivity literature by identifying psychological need satisfaction as the mechanism and Chinese traditionality as the moderator.
Synthesis and Physicochemical Study of Xanthan Butyl Ether

Xanthan is an important polysaccharide widely used in many industrial fields. It is produced by the bacteria Xanthomonascampestris. Chemical modification of xanthan can open up new horizons for its use. In this work, xanthan butyl ester was obtained for the first time by the interaction of xanthan and bromobutane using sodium hydroxide as a catalyst. The composition and structure of the obtained new xanthan derivative was studied by elemental analysis, IR spectroscopy, X-ray phase analysis, scanning electron microscopy and thermal analysis. The introduction of a butyl group into the xanthan molecule was proved by elemental analysis and IR spectroscopy by the appearance of corresponding bands. It was shown by X-ray phase analysis that xanthan butyl ether has a more X-ray amorphous structure in comparison with the original xanthan. It was shown by scanning electron microscopy that xanthan butyl ether powder consists of particles of a larger size and a layered structure in comparison with the original xanthan. It has been shown by thermal analysis that xanthan butyl ether is less thermostable than the starting xanthan
Assessment of COPD burden through its stages

The study included 300 patients with COPD who are current smokers. Overall, 98% of them were males, and all were older than 40 years. Patients were classified into three groups: mild, moderate, and severe. Amount of cigarettes was found to be directly proportionate to COPD burden. Regarding weight burden, obesity wasn’t found to be a sign of increasing burden of the disease, while cachexia was found in the more severe COPD stage. We found that dyspnea and other symptoms of the disease were found to be increased with increased disease severity indicating more health burden with the more severe COPD stages. Also ,Mental health status had a direct positive correlation with COPD severity.
Revealing Changes in the Stem Form and Volume Allocation in Diverse Boreal Forests Using Two-Date Terrestrial Laser Scanning

Tree growth is a multidimensional process that is affected by several factors. There is a continuous demand for improved information on tree growth and the ecological traits controlling it. This study aims at providing new approaches to improve ecological understanding of tree growth by the means of terrestrial laser scanning (TLS). Changes in tree stem form and stem volume allocation were investigated during a five-year monitoring period. In total, a selection of attributes from 736 trees from 37 sample plots representing different forest structures were extracted from taper curves derived from two-date TLS point clouds. The results of this study showed the capability of point cloud-based methods in detecting changes in the stem form and volume allocation. In addition, the results showed a significant difference between different forest structures in how relative stem volume and logwood volume increased during the monitoring period. Along with contributing to providing more accurate information for monitoring purposes in general, the findings of this study showed the ability and many possibilities of point cloud-based method to characterize changes in living organisms in particular, which further promote the feasibility of using point clouds as an observation method also in ecological studies.
Intestinal malrotation with solitary jejunal diverticulum presenting as midgut volvulus in an adult: an unusual presentation

Intestinal malrotation with midgut volvulus presenting in adults is a rare entity, and association with jejunal diverticulum is rarer still. Herein, we report and review such a case of malrotation and volvulus, associated with intestinal band adhesions and a solitary jejunal diverticulum. This 67 years old gentleman had presented with complaints of intermittent abdominal pain for past several years. Imaging of the abdomen revealed twisting of superior mesenteric artery and vein, evidence of midgut volvulus and intestinal malrotation with “whirlpool sign”. Laparotomy revealed a midgut volvulus, extensive adhesions involving the root of the mesentery and a jejunal diverticulum. Adhesiolysis was performed, untwisting of the bowel was done and the jejunal diverticulum was resected. Post-operative period was uneventful. This case is being reported on account of its extreme rarity.
Recognition of LHD Position and Maneuvers in Underground Mining Excavations—Identification and Parametrization of Turns

The Inertial Measurement Unit (IMU) is widely used in the monitoring of mining assets. A good example is the Polish underground copper ore mines of KGHM, where research work with the use of the IMU has been carried out for several years. The potential of inertial sensors was ensured by the development of advanced analytics using machine learning methods to support the maintenance management of an extensive machine park and machine manufacturer in adapting various construction elements to mining conditions. The key algorithms developed in the field of inertial data concern: identification of cycles and components of the haulage process operations, identification of dynamic overloads, technical diagnostics of rotating elements, assessment of road conditions (bumps, slopes, damages), assessment of the technical condition of the pavement, assessment of the operator’s driving style, and finally the machine location in the mining excavation. One of the key operational contexts, necessary in the development of analytics for underground mining vehicles, is the identification of the turning moment of the machine at the intersection together with the determination of the driving direction and the turn angle. In the case of a mine with a room-and-pillar system, where the excavation system has the Manhattan structure, it is possible to use many simplifications to correctly estimate the machine motion path. The identification of the spatial context and the turning maneuver is of key importance both in the development of the machine location system, but also in multi-dimensional analyzes, including the analysis of dynamic overloads or the assessment of the operator’s driving style and work safety. The article presents a comparison of several mathematical models used for the machine turn detection problem, which were trained and tested on the real-life industrial data recorded using IMU during a single working shift of the self-propelled machine.
Brain Wave Patterns in Patients With Chronic Low Back Pain: A Case-control Study

Introduction: Research evidence indicates that maladaptive reorganization of the brain plays a critical role in amplifying pain experiences and pain chronification; however, no clear evidence of change exists in brain wave activity among patients with chronic low back pain (CLBP). The objective of this study was to assess brain wave activity in patients with CLBP, compared to healthy controls. Methods: Twenty-five patients with CLBP and twenty-four healthy controls participated in the study. A quantitative electroencephalography device was used to assess brain wave activity in eyes-open and eyes-closed (EO and EC) conditions. The regional absolute and relative power of brain waves were compared between the groups. Results: Our results showed a significant increase in the absolute power of theta (F=5.905, P=0.019), alpha (F=5.404, P=0.024) waves in patients with CLBP compared to healthy subjects in both EC and EO conditions. Patients with CLBP showed a reduced delta absolute power in the frontal region (F=5.852, P=0.019) and augmented delta absolute power in the central region (F=5.597, P=0.022) in the EO condition. An increased delta absolute power was observed in the frontal (F=7.563 P=0.008), central (F=10.430, P=0.002), and parietal (F=4.596, P=0.037) regions in patients with CLBP compared to the healthy subjects in the EC condition. In the EC condition, significant increases in theta relative power (F=4.680, P=0.036) in the parietal region were also found in patients with CLBP. Conclusion: The increased absolute power of brain waves in people with CLBP may indicate cortical overactivity and changes in the pain processing mechanisms in these patients. Highlights Chronic low back pain (CLBP) increases the alpha, theta, and delta power in the brain. CLBP is associated with increased brain wave activity in the frontal, central, and parietal regions. Our findings suggest altered central pain processing in CLBP. Plain Language Summary Traditional diagnosis and treatment of CLBP are mainly focused on peripheral pathology. But, the modern neuroscience approach to pain highlights the role of cortical plasticity in chronic musculoskeletal pain. In this regard, several studies found structural and functional changes in the brain in patients with chronic pain. Detailed knowledge about cortical changes in CLBP can improve our understanding of mechanisms involved in CLBP, opening a new window to better treatment of LBP (Low back pain). This study investigated brain wave activity in patients with CLBP compared to healthy individuals. Our findings suggest increased brain activity in various parts of the brain in patients with chronic LBP. This finding indicates that CLBP treatment should focus on both peripheral and cortical factors rather than local tissue damage.
Transición social en niñas, niños, niñes y adolescentes con incongruencia de género: revisión y sugerencias de intervención a profesionales

Introducción: la transición social en niñas (os, es) y adolescentes con incongruencia de género, es una intervención no médica, completamente reversible, que genera beneficios en la salud mental, pero que ha sido poco estudiada. El objetivo es realizar una revisión bibliográfica al respecto y desde ahí derivar recomendaciones a las(os) profesionales que intervienen en el apoyo a estas (os, es) niñas (os, es), adolescentes y sus familias. Métodos: ll presente trabajo corresponde a una revisión entre los años 2010 – 2021 en revistas científicas en habla inglesa e hispana indexadas en PUBMED, SciELO y en Google Académico. Resultados: se describe la trayectoria en el desarrollo de la incongruencia de género. En las (os, es) prepúberes el interés está centrado en la persistencia y desistencia de la incongruencia de género y las distintas trayectorias. La transición social y la persistencia se pueden manifestar diferencialmente para niñas y niños trans. Realizar transición social en niñas (os, es) que lo solicitan favorece la salud mental. La familia y la comunidad viven sus propias transiciones. En Chile se han ido dando las condiciones en salud, educación y a nivel legislativo para apoyar la afirmación de género de las niñas (os, es) y adolescentes, pero falta educación respecto a la transición social en infancia y adolescencia. Conclusiones: dado los beneficios que genera la transición social en niñas (os, es) y adolescentes transgénero, se requiere que las(os) profesionales se eduquen e intervengan adecuadamente.
UV first order and second order derivative spectrophotometric method using amplitude and AUC technique for determination of sildenafil in bulk and in pharmaceutical formulation

Four simple, rapid, accurate, precise, reliable, and economical UV-spectrophotometric methods have been proposed for the determination of Sildenafil in bulk and in pharmaceutical formulation. “Method A” is first order derivative UV spectrophotometry using amplitude, “method B” is first order derivative UV spectrophotometry using area under curve technique, “method C” is second order derivative UV spectrophotometry using amplitude, and “method D” is second order derivative UV spectrophotometry using area under curve technique. The developed methods have shown best results in terms of linearity, accuracy, precision, and LOD and LOQ for bulk drug and marketed formulation as well. In N, N-dimethyl formamide (DMF), Sildenafil showed maximum absorbance at 292 nm. For “method A” amplitude was recorded at 313 nm while for “method B” area under curve was integrated in the wavelength range of 302-326 nm. For “method C” amplitude was measured at 297 nm while for “method D” area under curve was selected in the wavelength range of 281-310 nm. For methods A, B, C and D, Sildenafil obeyed Lambert-Beer’s law in the range of 05–50 µg/mL, and the correlation coefficients were found to be > than 0.999.