Miracle-dz/UniFAR-FTUs huggingface dataset:
Systematic Analysis of Cellular Signaling Pathways and Therapeutic Targets for SLC45A3:ERG Fusion-Positive Prostate Cancer

ETS-related gene (ERG) fusion affects prostate cancer depending on the degree of expression of ERG. Solute Carrier Family 45 Member 3 (SLC45A3) is the second-most common 5′ partner gene of ERG rearrangement. However, the molecular pathological features of SLC45A3:ERG (S:E) fusion and therapeutic methods have not been studied at all. S:E fusion-positive cancers (n = 10) were selected from the Tumor Fusion Gene Data Portal website. Fusion-negative cancers (n = 50) were selected by sorting ERG expression level in descending order and selecting the bottom to 50th sample. Totally, 1325 ERG correlated genes were identified by a Pearson correlation test using over 0.3 of absolute correlation coefficiency (|R| > 0.3). Pathway analysis was performed using over-representation analysis of correlated genes, and seven cancer-related pathways (focal adhesion kinase (FAK)/PI3K-Akt, JAK-STAT, Notch, receptor tyrosine kinase/PDGF, TGF-β, VEGFA, and Wnt signaling) were identified. In particular, focal adhesion kinase (FAK)/PI3K-Akt signaling and JAK-STAT signaling were significantly enriched in S:E fusion-positive prostate cancer. We further identified therapeutic targets and candidate drugs for S:E fusion-positive prostate cancer using gene–drug network analysis. Interestingly, PDGFRA and PDGFRB were the most frequently predicted therapeutic targets, and imatinib targeted both genes. In this study, we provide extensive information on cellular signaling pathways involved in S:E fusion-positive prostate cancer and also suggest therapeutic methods.
Bounds on self-interacting fermion dark matter from observations of old neutron stars

The existence of old neutron stars deeply constrains self-interacting fermion dark matter, which can form star-killing black holes. We quantify this constraint on dark matter-nucleon scattering, considering collapse scenarios that broaden bounds over intermediate masses. We then find the self- and co-annihilation rates necessary to lift these dark matter-nucleon scattering bounds. For Yukawa-coupled dark matter that fits dwarf galaxy halo profiles with a coupling $\alpha = 10^{-1}-10^{-4}$, a scalar mediator mass $m_\phi = 1-500$ MeV, and DM mass $m_X = 0.1-10^7$ GeV, we show that fermion dark matter is unconstrained if it self-annihilates at a rate greater than $10^{-40} ~ \rm{cm^3/s}$ or co-annihilates with baryons at a rate greater than $10^{-50} ~ \rm{cm^3/s}$.
Aspect-Bas1ed Sentiment Analysis on Twitter Using Logistic Regression with FastText Feature Expansion

Social media has recently been widely used by users, especially Indonesians, as a place to express themselves in sentences, pictures, sounds, or videos. Twitter is one of the social media favored by people of diverse ages. Twitter is a social media that provides features like social media in general. However, Twitter has a unique feature where users can send or read text messages limited to only a few characters. Therefore, user tweets with topics related to a particular product can be utilized by companies to become input in the development of these products. This research was conducted using tweet data on the topic of Telkomsel, which is divided into two aspects, namely signal and service. Aspect-based sentiment analysis of Telkomsel was carried out using Logistic Regression with FastText feature expansion to reduce vocabulary mismatch in tweets so that the classification stage can be performed optimally. In addition, the Synthetic Minority Oversampling Technique (SMOTE) sampling method was applied to overcome data imbalance. The test results prove that feature expansion can improve F1-Score values for signal and service aspects. For the signal aspect, F1-Score increased by 3.33% from the baseline with a value of 96.48%. While for the service aspect, F1-Score increased by 12.91% from the baseline with a value of 95.57%.
A High-Efficiency SISL-Based Slot Antenna Array for Wireless Power Transmission Application

A high-efficiency slot antenna array based on substrate integrated suspended line (SISL) technology operating at 24 GHz is presented for wireless power transmission (WPT) application. Because of the feature of self-shielding and low loss of SISL technology, double-side SISL (DSISL) is used to further reduce substrate and conductor loss in antenna design. Besides, four radiating slots are etched on the top ground layer of DSISL and serially fed as a subarray without any extra feeding network. By utilizing DSISL and avoiding network loss, a high efficiency subarray is realized with simulated efficiency of up to 89% at 24 GHz. In addition, the subarray is fabricated and measured. The measured results of subarray show that the 10 dB impedance bandwidth is from 23.75 to 24.1 GHz, which covers the WPT band (24 GHz ± 100 MHz). The measured gain of 13.1 dBi and radiation efficiency of 83.5% is achieved at 24 GHz. Besides, the width of air cavities can be further reduced to 0. 384λ0 (λ0 is the free space wavelength at 24 GHz), benefiting from the basic mode tangential electromagnetic (TEM) mode of DSISL, which is good for wide scanning phased array design. Based on the subarray, a 1×8 phased array is designed and fabricated. The measured results show that |S11| of −32 dB, isolation of 19 dB, and gain of 19.5 dBi is obtained at 24 GHz, while a wide scanning range of ±50°with gain drop less than 3.3 dB is achieved also at 24 GHz.
Reconnection-driven plasmoids in blazars: fast flares on a slow envelope

Minute-timescale TeV flares have been observed in several blazars. The fast flaring requires compact regions in the jet that boost their emission towards the observer at an extreme Doppler factor of delta>50. For TeV photons to avoid annihilation in the broad line region of PKS 1222+216, the flares must come from large (pc) scales challenging most models proposed to explain them. Here we elaborate on the magnetic reconnection minijet model for the blazar flaring, focusing on the inherently time-dependent aspects of the process of magnetic reconnection. I argue that, for the physical conditions prevailing in blazar jets, the reconnection layer fragments leading to the formation a large number of plasmoids. Occasionally a plasmoid grows to become a large, "monster" plasmoid. I show that radiation emitted from the reconnection event can account for the observed "envelope" of ~ day-long blazar activity while radiation from monster plasmoids can power the fastest TeV flares. The model is applied to several blazars with observed fast flaring. The inferred distance of the dissipation zone from the black hole and the typical size of the reconnection regions are R_diss~0.3-1 pc and l' \simless 10^{16} cm, respectively. The required magnetization of the jet at this distance is modest: sigma ~a few. Such dissipation distance R_diss and reconnection size l' are expected if the jet contains field structures with size of the order of the black-hole horizon.
Combining observational techniques to constrain convection in evolved massive star models

Abstract Recent stellar evolution computations indicate that massive stars in the range ~ 20-30 M⊙ are located in the blue supergiant (BSG) region of the Hertzsprung-Russell diagram at two different stages of their life: immediately after the main sequence (MS, group 1) and during a blueward evolution after the red supergiant phase (group 2). From the observation of the pulsationnal properties of a subgroup of variable BSGs (α Cyg variables), one can deduce that these stars belongs to group 2. It is however difficult to simultaneously fit the observed surface abundances and gravity for these stars, and this allows to constrain the physical processes of chemical species transport in massive stars. We will show here that the surface abundances are extremely sensitive to the physics of convection, particularly the location of the intermediate convective shell that appears at the ignition of the hydrogen shell burning after the MS. Our results show that the use of the Ledoux criterion to determine the convective regions in the stellar models leads to a better fit of the surface abundances for α Cyg variables than the Schwarzschild one.
Effect of magnetized phonons on electrical and thermal conductivity of neutron star crust

We study electrical and thermal conductivities of degenerate electrons emitting and absorbing phonons in a strongly magnetized crystalline neutron star crust. We take into account modification of the phonon spectrum of a Coulomb solid of ions caused by a strong magnetic field. Boltzmann transport equation is solved using a generalized variational method. The ensuing three-dimensional integrals over the transferred momenta are evaluated by two different numerical techniques, the Monte-Carlo method and a regular integration over the first Brillouin zone. The results of the two numerical approaches are shown to be in a good agreement. An appreciable growth of electrical and thermal resistivities is reported at quantum and intermediate temperatures $T \lesssim 0.1 T_{\rm p}$ ($T_{\rm p}$ is the ion plasma temperature) in a wide range of chemical compositions and mass densities of matter even for moderately magnetized crystals $\omega_{\rm B} \sim \omega_{\rm p}$ ($\omega_{\rm B}$ and $\omega_{\rm p}$ are the ion cyclotron and plasma frequencies). This effect is due to an appearance of a soft ($\omega \propto k^2$) phonon mode in the magnetized ion Coulomb crystal, which turns out to be easier to excite than acoustic phonons characteristic of the field-free case. These results are important for modelling magneto-thermal evolution of neutron stars.
The GALEX–SDSS NUV and FUV flux density and local star formation rate

We calculate the local ultraviolet (UV) flux density in the Galaxy Evolution Explorer (GALEX) Medium Imaging Survey (MIS) far-UV (FUV) and near-UV (NUV) bands using redshifts provided by Sloan Digital Sky Survey (SDSS) Data Release 7 (DR7). Luminosity functions are calculated for the overlapping MIS and SDSS sample, allowing flux densities to be measured and the local star formation rate (SFR) to be calculated using volumes much larger than previous FUV-based estimates. We calculate flux densities for a dust-corrected low-redshift (0.013 ≤ z ≤ 0.1) sample of f v-FUV = 22.24 ± 3.13 x 10 25 h erg s ―1 Hz ―1 Mpc ―3 , f v-NUV = 38.54 ± 5.30 x 10 25 h erg s ―1 Hz ―1 Mpc ―3 . The SFR density found is 0.0312 ± 0.0045 h M ⊙ yr ―1 Mpc ―3 . This is larger than published rates recently found using the UV implied SFR, though the major discrepancy is the correction made for dust attenuation and once this is dealt with consistently the results agree well. These values are also consistent with recent Hα derived SFRs. Once cosmic variance is taken into account most of the recent SFRs at low redshift (z ≤ 0.3) found in the literature can be brought into agreement, however, the lowest redshift values (z ≤ 0.045) do appear to be significantly lower.
Kinetic power of quasars and statistical excess of MOJAVE superluminal motions

The MOJAVE survey contains 101 quasars with a total of 354 observed radio components that are different from the radio cores, among which 95% move with apparent projected superluminal velocities with respect to the core, and 45% have projected velocities larger than 10c (with a maximum velocity 60c). Doppler boosting effects are analyzed to determine the statistics of the superluminal motions. We integrate over all possible values of the Lorentz factor the values of the kinetic energy corresponding to each component. The calculation of the mass in the ejection is carried out by assuming the minimum energy state. This kinetic energy is multiplied by the frequency at which the portions of the jet fluid identified as "blobs" are produced. Hence, we estimate the average total power released by the quasars in the form of kinetic energy in the long term on pc-scales. RESULTS. A selection effect in which both the core and the blobs of the quasar are affected by huge Doppler-boosting enhancement increases the probability of finding a jet ejected within 10 degrees of the line of sight >~40 times above what one would expect for a random distribution of ejection, which explains the ratios of the very high projected velocities given above. The average total kinetic power of each MOJAVE quasar should be very high to obtain this distribution: ~7E47 erg/s. This amount is much higher than previous estimates of kinetic power on kpc-scales based on the analysis of cavities in X-ray gas or radio lobes in samples of objects of much lower radio luminosity but similar black hole masses. The kinetic power is a significant portion of the Eddington luminosity, on the order of the bolometric luminosity, and proportional on average to square root of the radio luminosity, although this correlation might be induced by Malmquist-like bias.
Andreev spectroscopy of doped HgTe quantum wells

We investigate the Andreev reflection process in high-mobility HgTe/CdTe quantum wells. We find that Andreev conductance probes the dynamics of massive 2+1 Dirac fermions, and that both specular Andreev reflection and retroreflection can be realized even in presence of a large mismatch between the Fermi wavelengths at the two sides of the normal/superconducting junction.
GOOD CORPORATE GOVERNANCE (GCG) AND TALENT ANALYSIS MANAGEMENT FROM EMPLOYEE PERSPECTIVE

Human resources play an important role for driving the company. Companies that can mobilize their employees in maximizing their duties can reduce the negative impact of environmental factors, and will improve the company's financial performance. The purpose of this study is to analyze the role of applied GCG and Talent Management from an employee perspective, a case study of BPR Bakti in Sidoarjo. This study uses a qualitative descriptive approach, because it wants to solve problems related to employee performance at BPR Bakti, seen from the implementation of Good Corporate Governance and Talent Management. The stages of this research: (1) identify the role of GCG; (2) identify the role of Talent Management; (3) Identification of employee performance; and (4) analysis of the role of GCG and Talent Management in the context of developing effective employee performance. Based on the results of the study, it shows that the company has not implemented GCG related to employee performance, openly, and has not implemented Talent Management. The company also has not compiled employee personal development in the form of training and has not mapped the competencies of each employee, and there is no guidance, education and empowerment for employees as future leaders. The measurement of employee performance indicators is also not owned by the BPR, so there is no evaluation or assessment of employee performance. The factor that supports the performance of this BPR is the loyalty of the employees who work there. Keywords: Good Corporate Governance, Talent Management, Performance
Reversals of a large-scale field generated over a turbulent background

We present a study of several systems in which a large-scale field is generated over a turbulent background. These large-scale fields break a symmetry of the forcing by selecting a direction. Under certain conditions, the large-scale field displays reversals so that the symmetry of the forcing is recovered statistically. We present examples of such dynamics in the context of the dynamo instability, of two-dimensional turbulent Kolmogorov flows and of turbulent Rayleigh–Bénard convection. In these systems reversals occur respectively for the dynamo magnetic field, for the large-scale circulation generated by a periodic forcing in space and for the large-scale roll generated by turbulent thermal convection. We compare the mechanisms involved and show that their properties depend on some symmetries of the system and on the way they are broken.
Classi(cid:12)cation of maximally supersymmetric backgrounds in supergravity theories

: We study maximally supersymmetric solutions of all gauged or deformed supergravity theories in D (cid:21) 3 space-time dimensions. For vanishing background (cid:13)uxes the space-time background has to be either Minkowski or anti-de Sitter. We derive a simple criterion for the existence of solutions with non-trivial (cid:13)uxes and determine all supergravities that satisfy it. We show that their solutions coincide with those of the corresponding ungauged theories and conclude that the known list of maximally supersymmetric solutions is exhaustive.
Implicit Negative Link Prediction With a Network Topology Perspective

Sign prediction in signed social networks is a new research direction in the field of social relation mining, which reveals underlying links between users. Traditional sign prediction research focuses on the prediction of positive signs and neglects the mining of potential implicit links, and there is little research on negative sign prediction. To address these problems, we propose a two-stage model that uses implicit link detection and link sign prediction. First, we use the preference attachment closeness degree (PACD) to predict possible implicit links by adding a measure of relationship closeness to the traditional link prediction algorithm (PA). Next, we propose a negative link sign prediction (Ne-LP) method to predict relation types through multidimensional negative sign-related features, including those of nodes, user similarity, and structural balance, and merge them by a logistic regression model. Finally, we evaluate PACD and Ne-LP through extensive experiments on three real-world social network datasets, whose results demonstrate that the method can effectively mine implicit relations and accurately predict negative links.
Probing extra dimension through gravitational wave observations of compact binaries and their electromagnetic counterparts

The future gravitational wave (GW) observations of compact binaries and their possible electromagnetic counterparts may be used to probe the nature of the extra dimension. It is widely accepted that gravitons and photons are the only two completely confirmed objects that can travel along null geodesics in our four-dimensional space-time. However, if there exist extra dimensions and only GWs can propagate freely in the bulk, the causal propagations of GWs and electromagnetic waves (EMWs) are in general different. In this paper, we study null geodesics of GWs and EMWs in a five-dimensional anti-de Sitter space-time in the presence of the curvature of the universe. We show that for general cases the horizon radius of GW is longer than EMW within equal time. Taking the GW150914 event detected by the Advanced Laser Interferometer Gravitational-Wave Observatory and the X-ray event detected by the Fermi Gamma-ray Burst Monitor as an example, we study how the curvature k and the constant curvature radius l affect the horizon radii of GW and EMW in the de Sitter and Einstein-de Sitter models of the universe. This provides an alternative method for probing extra dimension through future GW observations of compact binaries and their electromagnetic counterparts.
Optical coupling to spin waves in the cycloidal multiferroic BiFeO3

The magnon and optical phonon spectrum of an incommensurate multiferroic such as BiFeO3 is considered in the framework of a phenomenological Landau theory. The resulting spin wave spectrum is quite distinct from commensurate substances due to soft mode anisotropy and magnon zone folding. The former allows electrical control of spin wave propagation via reorientation of the spontaneous ferroelectric moment. The latter gives rise to multiple magneto-dielectric resonances due to the coupling of optical phonons at zero wavevector to magnons at integer multiples of the cycloid wavevector. These results show that the optical response of a multiferroic reveals much more about its magnetic excitations than previously anticipated on the basis of simpler models.
On The MF Propety of Reduced Amalgamated Free Products of UHF Algebras

In this paper, we concentrate on the MF property of reduced free products of unital C*-algebras with amalgamation over finite dimensional C*-algebras. More specifically, we give a necessary and sufficient condition for a reduced free product of two UHF algebras amalgamated over a finite-dimensional C*-algebra with respect to trace preserving conditional expectations to be MF.
DIRECT IMAGING OF THE WATER SNOW LINE AT THE TIME OF PLANET FORMATION USING TWO ALMA CONTINUUM BANDS

Molecular snow lines in protoplanetary disks have been studied theoretically for decades because of their importance in shaping planetary architectures and compositions. The water snow line lies in the planet formation region at ≲10 AU, and so far its location has been estimated only indirectly from spatially unresolved spectroscopy. This work presents a proof-of-concept method to directly image the water snow line in protoplanetary disks through its physical and chemical imprint on the local dust properties. We adopt a physical disk model that includes dust coagulation, fragmentation, drift, and a change in fragmentation velocities of a factor of 10 between dry silicates and icy grains as found by laboratory work. We find that the presence of a water snow line leads to a sharp discontinuity in the radial profile of the dust emission spectral index αmm due to replenishment of small grains through fragmentation. We use the ALMA simulator to demonstrate that this effect can be observed in protoplanetary disks using spatially resolved ALMA images in two continuum bands. We explore the model dependence on the disk viscosity and find that the spectral index reveals the water snow line for a wide range of conditions, with opposite trends when the emission is optically thin rather than thick. If the disk viscosity is low (αvisc < 10−3), the snow line produces a ringlike structure with a minimum at αmm ∼ 2 in the optically thick regime, possibly similar to what has been measured with ALMA in the innermost region of the HL Tau disk.
In Vitro Antibacterial Activity of Different Bioceramic Root Canal Sealers

Bioceramic root canal sealers have been introduced in clinical dental use, but less is known about the antibacterial activity against Streptococcus mutans, Streptococcus salivarius, and Streptococcus sanguis. The purpose of the study is to compare new bioceramic sealers with a traditional zinc-oxide eugenol material considered as a control. The different bioceramic root canal sealants tested were FillRoot ST, BioRoot™RCS, Well-Root™ PT, and CeraSeal. In vitro antibacterial activity against Streptococci was assessed using the agar disc diffusion test at two different intervals, 24 h and 48 h. A non-parametric statistical analysis was performed to compare the inhibition zones for each of the different materials. Bioceramic root canal sealers showed mild antibacterial activity, while zinc-oxide eugenol-based material showed a stronger inhibition of Streptococci diffusion. No differences were detected for the measurements of inhibition zones between 24 h and 48 h except for FillRoot ST and BioRoot™RCS.