Miracle-dz/UniFAR-FTUs huggingface dataset:
Applications of Small-Angle X-ray Scattering on Biomacromolecular Solutions Running title (maximum 50 characters): X-ray Scattering from Biological Solutions

250 words max): Small-angle scattering of X-rays (SAXS) is an established method for low-resolution structural characterization of biological macromolecules in solution. Being highly complementary to the high resolution methods (X-ray crystallography and NMR), SAXS is often used in combination with them. The technique provides overall three-dimensional structures using ab initio reconstructions and hybrid modeling, and allows one to quantitatively characterize equilibrium mixtures and flexible systems. Recent progress in SAXS instrumentation, most notably, high brilliance synchrotron sources, pave the way for high throughput automated SAXS studies including screening of external conditions (pH, temperature, ligand binding etc). The modern approaches for SAXS data analysis are presented in this review including rapid characterization of macromolecular solutions in terms of lowresolution shapes, validation of high-resolution models in close-to-native conditions, quaternary structure analysis of complexes and quantitative description of the oligomeric composition in mixtures. Practical aspects of SAXS as a standalone tool and its combinations with other structural, biophysical or bioinformatics methods are reviewed. The capabilities of the technique are illustrated by recent selected applications for the studies of biological objects. The future perspectives of SAXS and their potential impact for structural molecular biology are discussed.
Responses of Phytoplankton and Bacterial Metabolism to CO2 Enrichment during a Bloom in a Coastal Mesocosm

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Impact of long-term electrically induced muscle exercise on gene signaling pathways, gene expression, and PGC1a methylation in men with spinal cord injury.

Exercise attenuates the development of chronic non-communicable diseases (NCDs). Gene signaling pathway analysis offers an opportunity to discover if electrically induced muscle exercise regulates key pathways among people living with spinal cord injury (SCI). We examined short-term and long-term durations of electrically induced skeletal muscle exercise on complex gene signaling pathways, specific gene regulation, and epigenetic tagging of PGC1a, a major transcription factor in skeletal muscle of men with SCI. After short or long-term electrically induced exercise training, participants underwent biopsies of the trained and untrained muscles. RNA was hybridized to an exon microarray and analyzed using a gene set enrichment analysis. We discovered that long-term exercise training regulated the Reactome gene sets for Metabolism (38 gene sets), Cell Cycle (36 gene sets), Disease (27 gene sets), Gene Expression and Transcription (22 gene sets), Organelle Biogenesis (4 gene sets), Cellular Response to Stimuli (8 gene sets), Immune System (8 gene sets), Vesicle Mediated Transport (4 gene sets), and Transport of Small Molecules (3 gene sets). Specific gene expression included: Oxidative catabolism of glucose including PDHB (p<0.001), PDHX (p<0.001), MPC1 (p<0.009), and MPC2 (p<0.007); Oxidative phosphorylation genes including SDHA (p<0.006), SDHB (p<0.001), NDUFB1 (p<0.002), NDUFA2 (p<0.001); Transcription Genes including PGC1α (p<0.030) and PRKAB2 (p<0.011); Hypertrophy gene MSTN (p<0.001); and the Myokine generating FNDC5 gene (p<0.008). Long-term electrically induced exercise de-methylated the major transcription factor, PGC1a. Taken together, these findings support that long term electrically induced muscle activity regulates key pathways associated with muscle health and systemic metabolism.
G¨odel-type universes and chronology protection in Hoˇrava-Lifshitz gravity

In the attempts toward a quantum gravity theory, general relativity faces a serious diﬃculty since it is non-renormalizable theory. Hoˇrava-Lifshitz gravity oﬀers a framework to circumvent this diﬃculty, by sacriﬁcing the local Lorentz invariance at ultra-high energy scales in exchange of power-counting renormalizability. The Lorentz symmetry is expected to be recovered at low and medium energy scales. If gravitation is to be described by a Hoˇrava-Lifshitz gravity theory there are a number of issues that ought to be reexamined in its context, including the question as to whether this gravity incorporates a chronology protection, or particularly if it allows G¨odel-type solutions with violation of causality. We show that Hoˇrava-Lifshitz gravity only allows hyperbolic G¨odel-type space-times whose essential parameters m and ω are in the chronology respecting intervals, excluding therefore any noncausal G¨odel-type space-times in the hyperbolic class. There emerges from our results that the famous noncausal G¨odel model is not allowed in Hoˇrava-Lifshitz gravity. The question as to whether this quantum gravity theory permits hyperbolic G¨odel-type solutions in the chronology preserving interval of the essential parameters is also examined. We show that Hoˇrava-Lifshitz gravity not only excludes the noncausal G¨odel universe, but also rules out any hyperbolic G¨odel-type solutions for physically well-motivated perfect-ﬂuid matter content.
I Jrlear Logic Semantics for Concurrent Prolog

This paper develops a proof-theoretic semantics based on linear logic for Concurrent Prolog. Several fragments of linear logic are used in order to provide for a suitable translation of Concurrent Prolog clauses, with the committed-choice concurrency features captured by the properties of linear logic provability rather than by some additional mechanism and without the need of using the interleaving approach for defining concurrent behaviour. Linear logic operations from different fragments arise naturally from the need for specific features of the translation. It is demonstrated that the relationship between a logic programming language, such as Prolog, and a committed-choice concurrent logic one, such as Concurrent Prolog, can be understood as a change of the underlying logic inference, rather than by resorting to extra-logical machinery.
DESAIN DAN IMPLEMENTASI SISTEM MONITORING DAN MANAJEMEN BATERAI MOBIL LISTRIK DESIGN AND IMPLEMENTATION OF ELECTRIC CAR BATTERY MONITORING AND MANAGEMENT SYSTEM

mobil listrik. Dibutuhkan kontrol monitor secara tepat untuk menjadikan mobil listrik sebagai kendaraan yang efisien dengan managemen baterai yang tepat. Pada Tugas Akhir ini akan dirancang sistem monitoring dan manajemen baterai mobil listrik. Baterai pada mobil listrik akan diambil data. Data yang akan dimonitoring pada baterai adalah arus, tegangan. Data dari sensor lalu diolah dan dikirim menuju mikrokontroler Arduino Due. Lalu data tersebut ditampilkan pada LCD secara real-time. Setelah itu, dua buah baterai dibandingkan kapasitas tegangannya agar kapasitas kedua baterai seimbang. penelitian menunjukan Sistem 0.9 Abstract Currently, the development of electric cars in Indonesia is becoming the talk. Batteries become one of the discussion on electric cars. It takes control and monitor appropriately to make the electric car as an efficient vehicle with proper battery management. In this final project will be designed system monitoring and management of electric car batteries. The battery in an electric car will be taken data. Data to be monitored is the current battery voltage. Data from the sensor is processed and sent to the microcontroller Arduino Due. Then the data is displayed on the LCD in real-time. After that, two batteries than the capacity of the battery voltage in order to balance capacity. Results from this study indicate that the battery balancing system running but is very slow. Balancing system takes 12 hours 54 minutes for balancing battery with a voltage difference is 0.9 V. While the battery monitoring system can predict the remaining time and distance of oncoming cars well. At the table with the test results predicted 13,72A current travel time is 38.2 minutes and 1.83 km. The current measurements with an average of 13 Ampere and the average voltage of 12.4 V the car can drive for 32 minutes 24 seconds with the distance of 1.46 km. It can be said the prediction of rest distance and time running properly.
Dentin Matrix Protein 1 Gene Cis-regulation USE IN OSTEOCYTES TO CHARACTERIZE LOCAL RESPONSES TO MECHANICAL LOADING IN VITRO AND IN VIVO*

From the ‡Department of Periodontics and Cellular and Structural Biology, University of Texas, San Antonio, Texas 78229, the Department of Genetics and Developmental Biology, University of Connecticut Health Center, Farmington, Connecticut 06030, the ¶Department of Oral Biology, University of Missouri, Kansas City, Missouri 64109, the **Department of Orthodontics, University of Texas Health Science Center, San Antonio, Texas 78229, the ‡‡Department of Biomedical Engineering, Indiana University-Purdue University, Indianapolis, Indiana 46202, and the §§Department of Anatomy and Cell Biology, Indiana University School of Medicine, Indianapolis, Indiana 46202
Indoor Personal Monitoring, Supervising and Assistance Sweet-Home and AmiHomeCare case studies

This paper proposes a new solution for an e-health system architecture related to personal assistance at home for aged people. This architecture takes into account the results of two ongoing projects on which the authors are involved: Sweet-Home and AmiHomeCare and the possibility of combining different parts of these projects in order to obtain a more versatile system. Each project has a distinctive way of gathering the required information: Sweet-Home uses sound processing, AmiHomeCare - video processing. The paper analyzes the advantages and drawbacks of both approaches in order to propose an integrative new architecture.
A Retrospective Analysis of The Correlation Between the Type of Pulp Exposure and The Choice of Pulp Capping Agents

The aim was mainly to determine the correlation between the type of pulp capping method and the material of choice in this study. Pulp capping in the carious teeth has been considered as unpredictable and they mainly have a lesser success rate. The pulp capping can be mainly done in two methods; they are direct and indirect pulp capping, which can be mainly done with the help of different materials of choice like calcium hydroxide, MTA etc. The study was conducted in Saveetha Dental College. The data collection has been done from the department of Conservative dentistry and Endodontics for patients undergoing pulp capping treatment. A total sample data of 140 patients were obtained for a period of nine months ( June 2019 – April 2020.). Statistical analysis was done by using a chi-square test with SPSS software version 23. The results were obtained and tabulated, the type of pulp capping method was 67% of indirect pulp capping and 33% of direct pulp capping method in which 81% of calcium hydroxide, 8% of MTA and 11% of RMGIC were used as the materials of choice. Among which indirect pulp capping method was most commonly used than the direct pulp capping method with calcium hydroxide as the material of choice for the treatment (p < 0.05, which is statistically signi(cid:977)icant) . The pulpal exposure was mainly due to dental caries and mechanical preparation of the tooth. Within the limits of the present study, the most common type of the pulp exposure was due to dental caries and mechanical exposure during the cavity preparation of the tooth and the most common method of pulp capping was the indirect method with calcium hydroxide (CaOH) as the most common material of choice.
The Protein Kinase C Activator L-a-Dioctanoylglycerol: A Potent Stage II Mouse Skin Tumor Promoter1

Endogenous diacylglycerol, as produced during ligand-stimulated hy drolysis of phnsphatidylinositol, is a physiological activator of protein kinase C, a receptor for the tumor promoter 12-0-tetradecanoylphorbol-13-acetate (TPA). Diacylglycerol mimics many effects of phorbol ester TP A, but it is not known whether diacylglycerol is a mouse skin tumor promoter. The present studies determined the mouse skin tumor-promot ing activity of L-a-dioctanoylglycerol (DC), a membrane-permeable di acylglycerol derivative. In two independent experiments with female SENCAR mice, DG at a 2 nmol dose, when applied twice weekly to the initiated mouse skin, failed to promote mouse skin rumor formation. Similarly, DG lacked Stage I tumor-promoting activity, twice weekly applications of DG for 2 wk to the initiated mouse skin followed by twice weekly applications of mezerein (33 nmol) for as long as 27 wk elicited only a few papillomas per mouse. DG was found to be a potent Stage II mouse skin tumor promoter. In a typical two-stage tumor promotion experiment, SENCAR mice were initiated by application of 20 nmol of DMBA to their shaved backs. Two wk after initiation, 3.3 nmol of TPA were applied twice weekly for 2 wk (Stage I), and then 2 *imol of DG or 33 nmol of mezerein were applied to the skin twice weekly for the entire duration of the experiment (Stage II). Stage II tumor promotion with mezerein and DG resulted in 1333 Â±0.88 and 11.13 Â±1.25 papillomas per mouse, respectively, at 19 wk and the carcinoma incidence, 43% and 33%, respectively, at 27 wk of promotion. The tumor-promoting activity of DG was compared with the parent alcohol glycerol, and it was found that glycerol, at a dose as high as 11 nmol, was not a complete, Stage I or Stage II mouse skin tumor promoter. Both TPA and DG, when applied to mouse skin, induced epidermal ornithine decarboxylase activity. Both TPA and DG activate protein kinase C, but the results presented indicate that TPA and DG differ in their tumor-promoting properties. DG, like mezerein, is a Stage II mouse skin tumor promoter.
Exposure to adverse experiences in chi ldhood

Violent manifestations are part of our everyday reality and have been present among people from the beginning of humanity. Despite these overwhelming facts, it is only in the last decades that the research community has directed their efforts in studying violence against children. Recent research findings indicate that violence can take several forms (physical, psychological, electronic), it can take place at different levels of human interaction and its effects can be long lasting throughout the lifespan (Pinheiro, 2006; Butchart, Phinney Harvey, Kahane, Mian, Furniss, 2006). The World Health Organization (WHO) defines child maltreatment as "all forms of physical and/or emotional ill-treatment, sexual abuse, neglect or negligent treatment or commercial or other exploitation, resulting in actual or potential harm to the child's health, survival, development or dignity in the context of a relationship of responsibility, trust or power" (p. 16) (Krug, Dahlberg, Mercy, Zwi, Lozano, 2002). Children are considered to be one of the social categories who are the most vulnerable to abuse and maltreatment. They can be exposed to abuse at home, in schools, on the playground or in other public or private institutions. Also, the abuser can vary, from a parent or other family members, to people who live in the same community, teachers, people who work in different childcare institutions, or even peers. The 2006 United Nations report on violence against children stresses that "no country is immune to this phenomenon, the violent manifestations cut across boundaries of geography, race, class, religion and culture" (p.XI) (Pinheiro, 2006), thus emphasizing the wide spread nature and intensity of this phenomenon. The prevention of child abuse and maltreatment is a priority worldwide (Krug et al. , 2002; Pinheiro, 2006; Butchart et al. , 2006; Sethi et al. , 2013). The WHO Regional Office for Europe has recently released a new report which outlines the high burden of child maltreatment, its causes and consequences, and the costeffectiveness of prevention programs. In order to estimate the prevalence of child maltreatment in Europe, a combined analysis of all the community surveys available for the prevalence of child abuse and maltreatment have been aggregated. According to this data, the prevalence of child physical abuse in Europe is 22.9% and child emotional abuse is 29.1%. The estimated prevalence of childhood sexual abuse in Europe is 9.6% (13.4% girls and 5.7% boys), and the prevalence of physical neglect is 16.3% and emotional neglect is 18.4%. Thus, at least 10% of European children experience some form of maltreatment. It is probable that the real prevalence of child abuse and maltreatment is higher due to problems associated with underreporting (Norman, Byambaa, De, Butchart, Alina Cosma
This is a repository copy of Explaining Cross-National Variations in the Prevalence of Informal Sector Entrepreneurship: lessons from a survey

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Effect of cold stress on growth performance, carcass traits, blood parameters and antioxidant enzymes in different broilers strains

The present study aimed to investigate the effect of cold stress on the different broiler strains performance. A total of 2000-day old chicks of five strains (Cobb 500, Ross 308, Avian 48, Arbor Acres (A.A.) and Indian River (IR) each of 400 chicks were randomly assigned into two groups one subjected to cold stress and the second was considered control group. Cold stressed groups were housed in a closed house supplied with cooling pads to provide ambient temperature at 29 C during 1 week, 25 C during 2 week, 20 C during 3 week, 16 C from 4 till 7 weeks of age. Results indicated that cold stress had significantly reduced final weight (2291.94 vs. 2635.36 g), total weight gain (2248.86 vs. 2592.00 g) with significant increase in feed consumption (4996.00 vs. 4694.88 g) and feed conversion ratio (2.23 vs. 1.81), while mortality rate had significantly increased in cold stressed broilers (8.88 % vs. 2.60 %). Cobb were showed lower affection by cold stress than other stains in growth performance and mortality rate, as Cobb had highest body weight in heat stressed groups (2414.21 vs. 2333.22, 2249.82, 2159.56 and 2302.90 g), similarly total weight gain, while Cobb had significantly lower feed intake and feed conversion ratio and mortality %. Carcass traits, antioxidant enzymes and blood biochemical parameters also had significantly affected by cold stress and in the same way Cobb showed significantly lower affection. In conclusion, cold stress adversely affect productivity of broilers, however Cobb 500 could be considered the most tolerant strain to cold.
Numerical and experimental study of electroadhesion to enable manufacturing automation

Robotics and autonomous systems (RAS) have great potential to propel the world to future growth. Electroadhesion is a promising and potentially revolutionising material handling technology for manufacturing automation applications. There is, however, a lack of an in-depth understanding of this electrostatic adhesion phenomenon based on a confident electroadhesive pad design, manufacture, and testing platform and procedure. This Ph.D. research endeavours to obtain a more comprehensive understanding of electroadhesion based on an extensive literature review, theoretical modelling, electrostatic simulation, and experimental validation based on a repeatable pad design, manufacture, and testing platform and procedure. [Continues. ]
A Systematic Review of the Effect of Local Cooling on Functional Performance

70 1, Introduction 70 2, Literature Search Methodology 71 2.1 Search Strategy 71 2.2 Inclusion Criteria 71 2.3 Selection ot Studies 71 2.4 Data Extraction and Management 71 2.5 Measures of Treatment Effect 71 2.6 Risk ot Bias 71 2.7 Subgroup Analysis 72 3, Results 7Ô 3.1 Included Studies 72 3.2 Details ot Outcome 72 3.3 Follow-Up 78 3.4 Risk ot Bias 78 3.5 Muscle Strength; Lower Limb (Thigh) 78 3.5. 1 Muscle Strength; Lower Limb (Calt/Ankle) 79 3.5. 2 Muscle Strength; Upper Limb 79 3.6 Muscie Endurance 79 3.7 Verficai Jump, Sprint and Agility Pertormance 80 3.8 Performance Accuracy 80 3.9 Upper Limb Dexterity 80 3,10 Summary of Immediate Effects ot Cooling 80 3.10,1 Duration of Effects Post-Cooling 80 3.10. 2 Cooling Dose 81 3.10,3 Adverse Effects 81 4, Discussion 82 4.1 Quality ot Evidence 8è 4.2 Muscle Strength 83 4.3 Muscle Endurance 83 4.4 Vertical Jump, Sprint and Agility Performance 83 4.5 Cooling Dose, Return to Sport and Warm Up 83