Miracle-dz/UniFAR-FTUs huggingface dataset:
Toward More Impactful International Business Education: A Teaching Innovation Typology

ABSTRACT Teaching innovations in the field of higher education (HE) have the potential to lead to better learning outcomes and higher faculty motivation. While the pedagogy literature has explored different types of teaching innovations, International Business (IB) scholars have paid relatively little attention to how these innovations are disseminated and generate impact across the IB field. This paper addresses this gap. Drawing on the innovation literature in management and the pedagogy literature on teaching innovations, we provide a typology of teaching innovations and their impact in the context of IB education. This framework illustrates the spread of teaching innovations by considering the intersection of types of pedagogy innovations, and the stakeholders impacted by them. By introducing this framework and illustrating select IB teaching innovations, we contribute to the pedagogy literature in the IB field. The framework also offers practical guidance for innovative educators and HE institutions.
Spreading Dynamics of Nanodrops: A Lattice Boltzmann Study

Spreading of nano-droplets is an interesting and technologically relevant phenomenon where thermal fluctuations lead to unexpected deviations from well-known deterministic laws. Here, we apply the newly developed fluctuating non-ideal lattice Boltzmann method [Gross et al., J. Stat. Mech. , P03030 (2011)] for the study of this issue. Confirming the predictions of Davidovich and coworkers [PRL 95, 244905 (2005)], we provide the first independent evidence for the existence of an asymptotic, self-similar noise-driven spreading regime in both two- and three-dimensional geometry. The cross over from the deterministic Tanner's law, where the drop's base radius $b$ grows (in 3D) with time as $b \sim t^{1/10}$ and the noise dominated regime where $b \sim t^{1/6}$ is also observed by tuning the strength of thermal noise.
Graph Neural Networks for High-Level Synthesis Design Space Exploration

High-level Synthesis (HLS) Design-Space Exploration (DSE) aims at identifying Pareto-optimal synthesis configurations whose exhaustive search is unfeasible due to the design-space dimensionality and the prohibitive computational cost of the synthesis process. Within this framework, we address the design automation problem by proposing graph neural networks that jointly predict acceleration performance and hardware costs of a synthesized behavioral specification given optimization directives. Learned models can be used to rapidly approach the Pareto curve by guiding the DSE, taking into account performance and cost estimates. The proposed method outperforms traditional HLS-driven DSE approaches, by accounting for the arbitrary length of computer programs and the invariant properties of the input. We propose a novel hybrid control and dataflow graph representation that enables training the graph neural network on specifications of different hardware accelerators. Our approach achieves prediction accuracy comparable with that of state-of-the-art simulators without having access to analytical models of the HLS compiler. Finally, the learned representation can be exploited for DSE in unexplored configuration spaces by fine-tuning on a small number of samples from the new target domain. The outcome of the empirical evaluation of this transfer learning shows strong results against state-of-the-art baselines in relevant benchmarks.
Sex differences in vitamin D metabolism, serum levels and action

Abstract The ubiquity of vitamin D metabolising enzymes and vitamin D receptors in mammalian organisms suggests that vitamin D has pleiotropic effects. There are quite a few studies indicating the anticancer, cardioprotective and antidiabetic effects of vitamin D; however, the best-documented actions of vitamin D are the regulation of Ca–phosphate balance and its effect on immune function. Vitamin D levels in organisms are modulated by many environmental and non-environmental factors. One potential factor that may influence vitamin D levels and effects is the sex of the individuals studied. This review focuses on the scientific evidence indicating different synthesis and metabolism of vitamin D in females and males, mainly from PubMed database sources. The article verifies the sex differences in vitamin D levels reported around the world. Moreover, the different effects of vitamin D on the musculoskeletal, cardiovascular, nervous and immune systems, as well as cancer in males and females, were discussed. Most studies addressing sex differences in vitamin D levels and effects are observational studies with conflicting results. Therefore, carefully designed clinical trials and experiments on animal models should be carried out to determine the role of non-environmental factors that may differentiate vitamin D levels in females and males.
Molecular dissipation in the nonlinear eddy viscosity in the Navier-Stokes equations: modelling of accretion discs

Physical damping, regarding the nonlinear Navier-Stokes viscous flow dynamics, refers to a tensorial turbulent dissipation term, attributed to adjacent moving macroscopic flow components. Mutual dissipation among these parts of fluid is described by a braking term in the momentum equation together with a heating term in the energy equation, both responsible of the damping of the momentum variation and of the viscous conversion of mechanical energy into heat. A macroscopic mixing scale length is currently the only characteristic length needed in the nonlinear modelling of viscous fluid dynamics describing the nonlinear eddy viscosity through the kinematic viscosity coefficient in the viscous stress tensor, without any reference to the chemical composition and to the atomic dimensions. Therefore, in this paper, we write a new formulation for the kinematic viscosity coefficient to the turbulent viscous physical dissipation in the Navier-Stokes equations, where molecular parameters are also included. Results of 2D tests are shown, where comparisons among flow structures are made on 2D shockless radial viscous transport and on 2D damping of collisional chaotic turbulence. An application to the 3D accretion disc modelling in low mass cataclysmic variables is also discussed. Consequences of the kinematic viscosity coefficient reformulation ina more strictly physical terms on the thermal conductivity coefficient for dilute gases are also discussed. The physical nature of the discussion here reported excludes any dependence by the pure mathematical aspect of the numerical modelling.
Monitoring the radio spectra of selected blazars in the Fermi-GST era. The Effelsberg 100 m telescope covering the cm band

The analysis of the spectral energy distribution variability at frequencies from radio to TeV is a powerful tool in the investigation of the dynamics, the physics and the structure evolution occurring in the most exotic flavour of active galaxies, the blazars. In particular, the presence of {\sl Fermi-GST} is providing a unique opportunity for such studies delivering $\gamma$-ray data of unprecedented quality. Here we introduce a monitoring program that has been running at the Effelsberg 100m telescope since January 2007, underpinning a broad multi-frequency collaboration of facilities that cover the band from radio to infrared. Sixty one selected blazars are observed monthly between 2.64 GHz and 43 GHz. The calibration accuracy is better than a few percent as it is demonstrated with some preliminary examples.
Corrections to Pauling residual entropy and single tetrahedron based approximations for the pyrochlore lattice Ising antiferromagnet

We study corrections to single tetrahedron based approximations for the entropy, specific heat and uniform susceptibility of the pyrochlore lattice Ising antiferromagnet, by a Numerical Linked Cluster (NLC) expansion. In a tetrahedron based NLC, the first order gives the Pauling residual entropy of ${1\over 2}\log{3\over 2}\approx 0.20273$. A 16-th order NLC calculation changes the residual entropy to 0.205507 a correction of 1.37 percent over the Pauling value. At high temperatures, the accuracy of the calculations is verified by a high temperature series expansion. We find the corrections to the single tetrahedron approximations to be at most a few percent for all the thermodynamic properties.
Cool dwarfs in wide multiple systems: Paper I: Two mid-M dwarfs in a loosely-bound common-proper-motion pair

This is the first of a series of works devoted to investigate cool dwarfs in wide multiple systems. Here, I present Koenigstuhl 4 A and B, two bright, intermediate M dwarfs with a common high proper-motion and separated by 299 arcsec. At the most probable distance of the system, 19 pc, the projected physical separation is 5700 AU, which makes Koenigstuhl 4 AB to be one of the least bound binary systems with late-type components found to date. I also associate the primary with a ROSAT X-ray source for the first time.
Baryon-Charge Chemical Potential in AdS/CFT

We present a closed framework of AdS/CFT with finite U(1)B-charge chemical potential. We show how the gauge-invariant identification of the chemical potential with the bulk gauge field emerges from the standard AdS/CFT dictionary. Physical importance and necessity of the Minkowski embeddings within the present framework is also shown numerically in the D3-D7 systems. We point out that the D3-D7 model with only the black-hole embeddings does not have the low-temperature and lowchemical-potential region in the grand-canonical ensemble, hence it is incomplete. A physical interpretation that explains these numerical results is also proposed.
THE UNIVERSAL INITIAL MASS FUNCTION IN THE EXTENDED ULTRAVIOLET DISK OF M83

We report deep Subaru Hα observations of the extended ultraviolet (XUV) disk of M83. These new observations enable the first complete census of very young stellar clusters over the entire XUV disk. Combining Subaru and Galaxy Evolution Explorer data with a stellar population synthesis model, we find that (1) the standard, but stochastically sampled, initial mass function (IMF) is preferred over the truncated IMF because there are low-mass stellar clusters (102–3 M☉) that host massive O-type stars; (2) the standard Salpeter IMF and a simple aging effect explain the counts of far-UV (FUV)-bright and Hα-bright clusters with masses >103 M☉; and (3) the Hα-to-FUV flux ratio over the XUV disk supports the standard IMF. To reach conclusion (2), we assumed instantaneous cluster formation and a constant cluster formation rate over the XUV disk. The Subaru Prime Focus Camera covers a large area even outside the XUV disk—far beyond the detection limit of the H i gas. This enables us to statistically separate the stellar clusters in the disk from background contamination. The new data, model, and previous spectroscopic studies provide overall consistent results with respect to the internal dust extinction (AV ∼ 0.1 mag) and low metallicity (∼0.2 Z☉) using the dust extinction curve of the Small Magellanic Cloud. The minimum cluster mass for avoiding the upper IMF incompleteness due to stochastic sampling and the spectral energy distributions of O, B, and A stars are discussed in the Appendices.
Shortcomings of the big bounce derivation in loop quantum cosmology

We give a prescription to define in loop quantum gravity the electric field operator related to the scale factor of a homogeneous and isotropic cosmological space-time. This procedure allows us to link the fundamental theory with its cosmological implementation. In view of the conjugate relation existing between holonomies and fluxes, the edge length and the area of surfaces in the fiducial metric satisfy a duality condition. As a consequence, the area operator has a discrete spectrum also in loop quantum cosmology. This feature makes the super-Hamiltonian regularization an open issue of the whole formulation.
Compact symmetric objects and supermassive binary black holes in the VLBA Imaging and Polarimetry Survey

We present multi-frequency Very Long Baseline Array (VLBA) follow-up observations of VLBA Imaging and Polarimetry Survey sources identified as likely compact symmetric objects (CSOs) or super-massive binary black holes (SBBHs). We also present new spectroscopic redshifts for 11 sources observed with the Hobby-Eberly Telescope. While no new SBBHs can be confirmed from these observations, we have identified 24 CSOs in the sample, 15 of which are newly designated, and refuted 52 candidates leaving 33 unconfirmed candidates. This is the first large uniform sample of CSOs which can be used to elicit some of the general properties of these sources, including morphological evolution and environmental interaction. We have detected polarised emission from two of these CSOs the properties of which are consistent with Active Galactic Nuclei unification schemes.
TESTING ALTERNATIVE THEORIES OF GRAVITY USING THE SUN

We propose a new approach to test possible corrections to Newtonian gravity using solar physics. The high accuracy of current solar models and new precise observations allow us to constrain corrections to standard gravity at unprecedented levels. Our case study is Eddington-inspired gravity, an attractive modified theory of gravity which results in non-singular cosmology and collapse. The theory is equivalent to standard gravity in vacuum, but it sensibly differs from it within matter. For instance, it affects the evolution and the equilibrium structure of the Sun, giving different core temperature profiles, and deviations in the observed acoustic modes and in solar neutrino fluxes. Comparing the predictions from a modified solar model with observations, we constrain the coupling parameter of the theory, |κg| ≲ 3 × 105 m5 s−2 kg−1. Our results show that the Sun can be used to efficiently constrain alternative theories of gravity.
Engineered decoherence: Characterization and suppression

Due to omnipresent environmental interferences, quantum coherences inevitably undergo irreversible transformations over certain time-scales, thus leading to the loss of encoded information. This process, known as decoherence, has been a major obstacle in realizing efficient quantum information processors. Understanding the mechanism of decoherence is crucial in developing tools to inhibit it. Here we utilize a method proposed by Cory and co-workers [Phys. Rev. A 67, 062316 (2003)] to engineer artificial decoherence in the system qubits by randomly perturbing their surrounding ancilla qubits. Using a two qubit nuclear magnetic resonance quantum register, we characterize the artificial decoherence by noise spectroscopy and quantum process tomography. Further, we study the efficacy of dynamical decoupling sequences in suppressing the artificial decoherence. Here we describe the experimental results and their comparisons with theoretical simulations.
ONE MOMENT IN TIME—MODELING STAR FORMATION IN THE ANTENNAE

We present a new high-resolution N-body/smoothed particle hydrodynamics simulation of an encounter of two gas-rich disk galaxies that closely matches the morphology and kinematics of the interacting Antennae galaxies (NGC 4038/39). The simulation includes radiative cooling, star formation, and feedback from Type II supernovae. The large-scale morphology and kinematics are determined by the internal structure and the orbit of the progenitor disks. The properties of the central region, in particular the starburst in the overlap region, only match the observations for a very short time interval (Δt ≈ 20 Myr) after the second encounter. This indicates that the Antennae galaxies are in a special phase only about 40 Myr after the second encounter and 50 Myr before their final collision. This is the only phase in the simulation when a gas-rich overlap region between the nuclei is forming accompanied by enhanced star formation. The star formation rate as well as the recent star formation history in the central region agree well with observational estimates. For the first time, this new model explains the distributed extra-nuclear star formation in the Antennae galaxies as a consequence of the recent second encounter. The proposed model predicts that the Antennae are in a later merger stage than the Mice (NGC 4676) and would therefore lose their first place in the classical Toomre sequence.
Microscopic Picture of Non-Relativistic Classicalons

A theory of a non-relativistic, complex scalar field with derivatively coupled interaction terms is investigated. This toy model is considered as a prototype of a classicalizing theory and in particular of general relativity, for which the black hole constitutes a prominent example of a classicalon. Accordingly, the theory allows for a non-trivial solution of the stationary Gross-Pitaevskii equation corresponding to a black hole in the case of GR. Quantum fluctuations on this classical background are investigated within the Bogoliubov approximation. It turns out that the perturbative approach is invalidated by a high occupation of the Bogoliubov modes. Recently, it was proposed that a black hole is a Bose-Einstein condensate of gravitons that dynamically ensures to stay at the verge of a quantum phase transition. Our result is understood as an indication for that claim. Furthermore, it motivates a non-linear numerical analysis of the model.
Improved parameters of seven Kepler giant companions characterized with SOPHIE and HARPS-N

Radial-velocity observations of Kepler candidates obtained with the SOPHIE and HARPS-N spectrographs have permitted unveiling the nature of the five giant planets Kepler-41b, Kepler-43b, Kepler-44b, Kepler-74b, and Kepler-75b, the massive companion Kepler-39b, and the brown dwarf KOI-205b. These companions were previously characterized with long-cadence (LC) Kepler data. Here we aim at refining the parameters of these transiting systems by i) modelling the published radial velocities (RV) and Kepler short-cadence (SC) data that provide a much better sampling of the transits, ii) performing new spectral analyses of the SOPHIE and ESPaDOnS spectra, and iii) improving stellar rotation periods hence stellar age estimates through gyrochronology, when possible. Posterior distributions of the system parameters were derived with a differential evolution Markov chain Monte Carlo approach. Our main results are as follows: a) Kepler-41b is significantly larger and less dense than previously found because a lower orbital inclination is favoured by SC data. This also affects the determination of the geometric albedo that is lower than previously derived: Ag < 0.135; b) Kepler-44b is moderately smaller and denser than reported in the discovery paper; c) good agreement was achieved with published Kepler-43, Kepler-75, and KOI-205 system parameters, although the host stars Kepler-75 and KOI-205 were found to be slightly richer in metals and hotter, respectively; d) the previously reported non-zero eccentricities of Kepler-39b and Kepler-74b might be spurious. If their orbits were circular, the two companions would be smaller and denser than in the eccentric case. The radius of Kepler-39b is still larger than predicted by theoretical isochrones. Its parent star is hotter and richer in metals than previously determined. [ABRIDGED]
Directed evolution of mesophilic HNA polymerases providing insight into DNA polymerase mechanisms

Detailed biochemical characterization of natural and mutant enzymes provides essential clues to understand their mechanisms. There are, however, limits to the throughput of such approaches and they are not without errors. DNA polymerases have benefited from over 50 years of detailed study and remain not fully understood. As such, methods that allow high-throughput interrogation of variants, and viable analysis pipelines to identify relevant variants, become an important tool to accelerate research. Using the DNA polymerase from B. subtilis Phi29 bacteriophage as a model, we demonstrate how coupling focused libraries, selection and deep sequencing can be combined to identify variants of interest for characterization. As selection parameters can be controlled, different areas of an enzyme’s mechanism can be explored. Focusing selection on faster HNA (1,5-anhydrohexitol nucleic acid) synthesis, we identified P562del as a variant of interest, enriching significantly between rounds. Characterization confirmed its faster HNA synthesis initiation but lower processivity and fidelity. P562 is a non-conserved residue, unlikely to be selected by more traditional approaches, but its deletion recapitulates knowledge on how Phi29 exonuclease, thumb and TPR2 subdomains regulate polymerase function. Our data further support the hypothesis that Phi29 shows a two-state binding to its template: a fast non-replicative complex that transitions to a replication-competent state.
Pipeline for transferring annotations between proteins beyond globular domains

Background DisProt is the primary repository of Intrinsically Disordered Proteins. This database is manually curated and the annotations there have strong experimental support. Currently DisProt contains a relatively small number of proteins highlighting the importance of transferring verified disorder and other annotations, in such a way as to increase the number of proteins that could benefit from this valuable information. While the principles and practicalities of homology transfer are well-established for globular proteins, these are largely lacking for disordered proteins. Methods We used DisProt to evaluate the transferability of the annotation terms to orthologous proteins. For each protein, we looked for their orthologs, with the assumption that they will have a similar function. Then, for each protein and their orthologs we made multiple sequence alignments (MSAs). Global and regional quality of the MSAs was evaluated with the NorMD score. Results We have designed a pipeline to obtain good quality MSAs and to transfer annotations from any protein to their orthologs. Applying the pipeline to DisProt proteins, from the 1931 entries with 5,623 annotations we can reach 97,555 orthologs and transfer a total of 301,190 terms by homology. We also provide a web server for consulting the results of DisProt proteins and execute the pipeline for any other protein. The server Homology Transfer IDP (HoTIDP) is accessible at http://hotidp.leloir. org.ar.
A Revised Characterization of the WFPC2 CTE Loss

Charge transfer loss on the Wide Field Planetary Camera 2 (WFPC2) onboard the Hubble Space Telescope is a primary source of uncertainty in stellar photometry obtained with this camera. This effect, discovered shortly after the camera was installed, has grown over time and can dim stars by several tenths of a magnitude (or even more, in particularly bad cases). The impact of CTE loss on WFPC2 stellar photometry was characterized by several studies between 1998 and 2000, but has received diminished attention since ACS became HST’s primary imager. After the failure of ACS in January 2007, WFPC2 once again became the primary imaging instrument on board HST, restoring the importance of ensuring accurate CTE corrections. This paper reexamines the CTE loss of WFPC2, with three significant changes over previous studies. First, the present study considers calibration data obtained through 2007, thus increasing the confidence in the reliability of the CTE corrections when applied to recent observations. Second, the change in CTE loss during readout is accounted for analytically. Finally, a reanalysis of the CTE dependencies on counts, background, and observation date was made. The resulting correction is significantly more accurate than that provided in the WFPC2 Instrument Handbook (Dolphin and updates through 2004), resulting in photometry that can be enhanced by over 5% in certain circumstances.