Miracle-dz/UniFAR-FTUs huggingface dataset:
Effect of Cylinder Roughness on Strouhal Number

The main goal of this paper is to establish a better understanding of the relationship between a Strouhal number and surface roughness. Hot-wire anemometry was used to evaluations the characteristics of turbulent flow behind circular cylinders with different relative roughness 0% (smooth surface) 0.83%, 1.67%, 3.33%, and 6.67%. At the experimental investigation, the Reynolds number based on the cylinder diameter was 5 × 103 < Red < 2 × 104. The obtained data showed that the Strouhal number decreased with increasing roughness. While, the dissipation rate decreases, and the value of the Kolmogorov and Taylor microscales increases. Also, spectral analysis of streamwise velocity fluctuations allowed us to estimate the location of the vortex-shedding frequency which at growing roughness tends to reduce.
Selecting Audio and Visual Stimuli: What Do We Prefer If They Happened Simultaneously?

Visual and audio stimuli become increasingly important in human lives as technology advances. To consider how humans receive, process, and react to stimuli, we investigate attention, specifically selective attention. Selective attention describes how humans focus on a particular stimulus in the environment for a certain period. The present study aimed to examine how do individuals make choices between auditory and visual stimuli. Ten participants with the age range from 15 to 22 years participated in this study. They were asked to choose between pairs of visual and auditory stimuli. The reaction time and congruence were recorded. The result showed that, compared to auditory stimuli, participants preferred responding to visual stimuli rather than auditory stimuli. The time it took to answer visual stimuli was longer than auditory stimuli, and the results were consistent. According to the result, we can conclude that individuals were more sensitive to visual stimuli than auditory stimuli.
The mediating role of green product innovation (GPI) between green human resources management (GHRM) and green supply chain management (GSCM): evidence from automotive industry companies in Turkey

ABSTRACT Today, the establishment of strong supply chain structures should be supported by a strong human resources management approach, as well as encompassing environmentalist and innovative approaches. At this point, this study has two main aims that include these requirements. The first aim is to determine whether the green human resources management (GHRM) of companies operating in the automotive industry has a direct impact on green supply chain management (GSCM). The second aim is to determine whether green product innovation (GPI) has a mediating effect in the relation GHRM and GSCM. Structural equation modelling is used to test the developed hypotheses. GHRM of automotive companies operating in Turkey has a significant positive effect on GSCM. In addition, GPI has a full mediating role in the relationship between GHRM and GSCM. Green-oriented should be establishment in the supply chain structures. Green-oriented human resources management approach is necessary to develop a green-oriented SCM. GHRM approach should be strengthened with GPI activities for GSCM.
The effect of thoracic epidural analgesia on short-term outcome and mortality in geriatric patients undergoing open heart surgery

ABSTRACT BACKGROUND: In open-heart surgeries, many organ functions, particularly the respiratory system, are affected by post-operative pain, and so is mortality. Following open-heart surgery, geriatric patients have a higher risk of organ dysfunction and mortality. We aimed to compare the short-term outcomes and mortality of thoracic epidural analgesia (TEA) and intravenous (IV) analgesia in geriatric patients undergoing open heart surgery. METHODS: This study included patients over the age of 65 who had open-heart surgery between 2010 and 2020. The patients were divided into two groups: Those who received TEA (Group E) and those who received IV paracetamol or tramadol or dexmedetomidine (Group I). The patients’ post-operative sedation and analgesia requirements, mechanical ventilation (MV) duration, blood glucose levels, liver and kidney function tests, complications, intensive care and hospital stay lengths, and mortality rates were all compared. RESULTS: The study included a total of 548 patients, with 408 in Group E and 140 in Group I. As a result of the comparisons between the groups, sedation requirement, analgesia requirement, MV duration, post-extubation facial mask oxygen requirement, non-invasive MV need, re-intubation requirement, and blood glucose level were found to be lower in Group E than in Group I. Moreover, periods spent in intensive care and lengths of hospital stay were found to be lower in Group E than Group I. There was no difference found between the two groups in terms of hospital mortality. CONCLUSION: In elderly patients undergoing open-heart surgery, TEA reduced the length of time in intensive care and hospital stays by improving the respiratory status and blood glucose regulation by supplying analgesia and sedation.
Challenges in Rail Vehicle-Track Modeling and Simulation

Rail vehicle-track modeling and simulations, in past many years is developed a long way from its origins as a research tool. This paper presents an overview of the current features and applications for components of rail vehicle-track dynamic modeling and few challenges which these applications find while doing the simulations. This paper discusses appropriate modeling choices for different applications and analyse the best practice for the optimum performance of suspension components, wheel-rail contact conditions and modeling inputs such as track geometry.
DeepSleep 2.0: Automated Sleep Arousal Segmentation via Deep Learning

DeepSleep 2.0 is a compact version of DeepSleep, a state-of-the-art, U-Net-inspired, fully convolutional deep neural network, which achieved the highest unofficial score in the 2018 PhysioNet Computing Challenge. The proposed network architecture has a compact encoder/decoder structure containing only 740,551 trainable parameters. The input to the network is a full-length multichannel polysomnographic recording signal. The network has been designed and optimized to efficiently predict nonapnea sleep arousals on held-out test data at a 5 ms resolution level, while not compromising the prediction accuracy. When compared to DeepSleep, the obtained experimental results in terms of gross area under the precision–recall curve (AUPRC) and gross area under the receiver operating characteristic curve (AUROC) suggest a lightweight architecture, which can achieve similar prediction performance at a lower computational cost, is realizable.
In Vitro Hepatotoxic and Neurotoxic Effects of Titanium and Cerium Dioxide Nanoparticles, Arsenic and Mercury Co-Exposure

Considering the increasing emergence of new contaminants, such as nanomaterials, mixing with legacy contaminants, including metal(loid)s, it becomes imperative to understand the toxic profile resulting from these interactions. This work aimed at assessing and comparing the individual and combined hepatotoxic and neurotoxic potential of titanium dioxide nanoparticles (TiO2NPs 0.75–75 mg/L), cerium oxide nanoparticles (CeO2NPs 0.075–10 μg/L), arsenic (As 0.01–2.5 mg/L), and mercury (Hg 0.5–100 mg/L) on human hepatoma (HepG2) and neuroblastoma (SH-SY5Y) cells. Viability was assessed through WST-1 (24 h) and clonogenic (7 days) assays and it was affected in a dose-, time- and cell-dependent manner. Higher concentrations caused greater toxicity, while prolonged exposure caused inhibition of cell proliferation, even at low concentrations, for both cell lines. Cell cycle progression, explored by flow cytometry 24 h post-exposure, revealed that TiO2NPs, As and Hg but not CeO2NPs, changed the profiles of SH-SY5Y and HepG2 cells in a dose-dependent manner, and that the cell cycle was, overall, more affected by exposure to mixtures. Exposure to binary mixtures revealed either potentiation or antagonistic effects depending on the composition, cell type and time of exposure. These findings prove that joint toxicity of contaminants cannot be disregarded and must be further explored.
Layerwise Security Protection for Deep Neural Networks in Industrial Cyber Physical Systems

Although deep neural networks (DNNs) have been increasingly applied in industrial cyber physical systems (ICPSs), they are vulnerable to security attacks due to the tight interaction between cyber elements and physical elements. In this article, we aim to protect the core IP of DNNs, i.e., the model weights, against security attacks. Different from conventional approaches, a layerwise protection framework is proposed to ensure the confidentiality of DNN model weights during the inference procedure such that the security quality is maximized, while satisfying the latency constraint of the DNN task. Based on the layerwise execution characteristics of DNN tasks, the encrypted layer-related weights are decrypted and fed to the next layer of DNN in plaintext. CPU-field programmable gate array (FPGA) coscheduling is considered to accelerate the execution of confidentiality protection, where CPU is utilized to conduct the decryption of weights and FPGA is used to perform the layer execution of DNN. Considering to provide optimal confidential protection for each layer, the problem is transformed into a quality of security maximization problem subject to layerwise execution constraint and deadline constraint of the DNN application. Due to the problem being NP-hard, a fast approximation algorithm is proposed to obtain the near-optimal solution under given real-time and security constraints. Extensive experiments and a real-life ICPS application evaluate the efficiency of the proposed techniques.
The effect of dietary hemp and camelina cakes on liver fatty acid profile of ducks

ABSTRACT The objective of the study was to determine the effects of dietary hempseed or camelina cakes rich in n-3 polyunsaturated fatty acids (PUFA) on the fatty acid profile of liver lipids and carcass characteristics of ducks. A total of 108 one-day-old male ducks were allocated to 3 dietary treatments. The Control (C) group diet was supplemented with 15 and 20% rapeseed cake from days 1 to 23 and 24 to 49, respectively, whereas the rapeseed in Experimental 1 (HE) and Experimental 2 (CA) was replaced by hempseed cake and camelina cake in the same proportion, respectively. Inclusion of dietary hempseed cake resulted in higher carcass yield (P < 0.05) and growth performance (P < 0.05) but did not increase the proportion of liver n-3 PUFA (P > 0.05). Dietary enrichment with camelina cake reduced carcass yield (P < 0.05), feed intake (P < 0.01) but had no significant effect on the body weight and feed conversion ratio (P > 0.05) of ducks. The amount of n-3 PUFA and long-chain (LC) n-3 PUFA in the CA group was 2.47 and 2.35 times (P < 0.01) higher compared with that of the C group, respectively. The inclusion of dietary camelina has helped to produce a healthier human nutrition liver with an n-6/n-3n PUFA ratio of 3.38 .
Osteogenic Induction with Silicon Hydroxyapatite Using Modified Autologous Adipose Tissue-Derived Stromal Vascular Fraction: In Vitro and Qualitative Histomorphometric Analysis

Large bone defects requiring invasive surgical procedures have long been a problem for orthopedic surgeons. Despite the use of autologous bone grafting, satisfactory results are often not achieved due to associated limitations. Biomaterials are viable alternatives and have lately been used in association with Stromal Vascular Fraction (SVF), stem cells, and signaling factors for bone tissue engineering (BTE). The objective of the current study was to assess the biocompatibility of Silicon Hydroxyapatite (Si-HA) and to improve osteogenic potential by using autologous adipose-derived SVF with Si-HA in a rabbit bone defect model. Si-HA granules synthesized using a wet precipitation method were used. They were characterized using scanning electron microscopy (SEM), Fourier transform infrared (FTIR), and X-ray diffraction (XRD). A hemolysis assay was used to assess the hemolytic effects of Si-HA, while cell viability was assessed through Alamar Blue assay using MC3T3 mouse osteoblasts. The osteogenic potential of Si-HA both alone and with enzymatically/non-enzymatically-derived SVF (modified) was performed by implantation in a rabbit tibia model followed by histomorphometric analysis and SEM of dissected bone after six weeks. The results showed that Si-HA granules were microporous and phase pure and that the addition of Silicon did not influence Si-HA phase composition. Si-HA granules were found to be non-hemolytic on the hemolysis assay and non-toxic to MC3T3 mouse osteoblasts on the Alamar Blue assay. Six weeks following implantation Si-HA showed high biocompatibility, with increased bone formation in all groups compared to control. Histologically more mature bone was formed in the Si-HA implanted along with non-enzymatically-derived modified SVF. Bone formation was observed on and around Si-HA, reflecting osseointegration. In conclusion, Si-HA is osteoconductive and promotes osteogenesis, and its use with SVF enhances osteogenesis.
Genetic analysis of mitochondrial DNA from ancient Equus caballus bones found at archaeological site of Joseon dynasty period capital area

Objective To understand the domestication and spread of horses in history, genetic information is essential. However, mitogenetic traits of ancient or medieval horses have yet to be comprehensively revealed, especially for East Asia. This study thus set out to reveal the maternal lineage of skeletal horse remains retrieved from a 15th century archaeological site (Gongpyeongdong) at Old Seoul City in South Korea. Methods We extracted DNA from the femur of Equus caballus (SNU-A001) from Joseon period Gongpyeongdong site. Mitochondrial (mt) DNA (HRS 15128-16116) of E. caballus was amplified by polymerase chain reaction. Cloning and sequencing were conducted for the mtDNA amplicons. The sequencing results were analyzed by NCBI/BLAST and phylogenetic tool of MEGA7 software. Results By means of mtDNA cytochrome b and D-loop analysis, we found that the 15th century Korean horse belonged to haplogroup Q representing those horses that have historically been raised widely in East Asia. Conclusion The horse is unique among domesticated animals for the remarkable impact it has on human civilization in terms of transportation and trade. Utilizing the Joseon-period horse remains, we can obtain clues to reveal the genetic traits of Korean horse that existed before the introduction of Western horses.
Extracts of Gnetumafricanum(Gnetacae) Ameliorated Liver Injuries of Cyclophosphamide Immunosuppressed Rats.

Gnetum africanum(Gnatacae) is a ceremonial delicacy in many parts of Eastern Nigeria and the leaves are either eaten raw or are finely shredded and added to soup.The effect of cyclophosphamide (CP) administration on the liver biomarkers of albino rats and the possible protective role of G.africanum extract was studied. Thirty rats were randomly divided into six groups of five rats each. Groups I-V were injected intraperitoneally with 70 mg/kg of CP on the first day while group VI was not injected with cyclophosphamide. Group I received 10 mL/kg of distilled water orally. Groups II, III and IV received daily dose of 50, 100and 200 mg/kg of extract respectively and group V received levamisole (2.5 mg/kg) for 14 days. The rats were sacrificed 24h after thelast dose and blood samples collected through cardiac puncture into non-heparinized tubes, allowed to clot for 30 min and sera obtained was used for determination ofaspartate amino transaminase (AST), alanine amino transaminase (ALT) and alkaline phosphatase (ALP). Histopathology of rat liver was also carried out. Treatment with G. africanum ethanol extract produced significant (P<0.05) decrease in the values of ALT and AST while there were no significant changes (P>0.05) in ALP in Cyclophosphamide induced group. Histopathology examination of liver sections of untreated control group showed hypertrophied central vein with moderate purulent exudates accumulation while those treated with the extracts ameliorated the hepatic damage caused by CP. The present work revealed that G.africanum ethanol extract exerts liver protective effect in albino rats exposed to CP and may offer useful application as supplemental agent in the management of hepatic injuries arising from chemotherapy.
The Effects of a Pathway-in-the-Sky Display on Performance of a Two Axis Tracking Task by Instrument Rated Pilots

Author: Leonard W. Hennessy, HI Title: The Effects of a Pathway-in-the-Sky Display on Performance of a Two Axis Tracking Task by Instrument Rated Pilots Institution: Embry-Riddle Aeronautical University Degree: Master of Aeronautical Science Year: 1995 This study was founded on the premise that airplane cockpit operations, while generally safe and relatively efficient, can be made even more so by employing instrument displays which are potentially more intuitive than existing displays. A low fidelity flight simulator was used to conduct an experiment comparing the performance of twenty-four instrument rated pilot subjects on a two axis tracking task (an Instrument Landing System Approach) under three instrument display conditions: (1) conventional instruments (INST); (2) a Pathway-in-the-Sky (PITS) display; and (3) a combination of the two (BOTH). The primary hypothesis, that pilot performance using the PITS and BOTH display configurations would be more accurate than when using conventional instruments, was accepted. The results indicated that no significant difference existed between performance under the PITS and BOTH conditions; however, performance was significantly better under either the PITS or BOTH conditions than under the INST condition. The study concluded that use of the PITS and BOTH displays yielded superior performance on the tracking task, and that if performance on the low-fidelity flight simulator is ever at all a predictor of performance in an actual aircraft, then the PITS and BOTH displays might yield superior performance in actual flight, potentially resulting in safer instrument flight operations.
Human stem cells prevent flap necrosis in preclinical animal models: A systematic review

Background and Aim: Adipose-derived mesenchymal stem cells (ADSCs) have been proven effective to prevent distal skin flap necrosis in preclinical models. However, to appropriately translate these findings to clinical trials, the effect of ADSC of human origin (hADSC) needs to be evaluated. We hypothesize that hADSC treatment is as effective as animal ADSC treatment at preventing distal skin flap necrosis in animal flap models. Methods: Three databases were inquired on August 17, 2020, to evaluate the necrotic flap area after using hADSCs in animal models of ischemic flaps. No publication status or dates were considered. Studies were included if they used hADSCs, measured the surviving or necrotic skin area of flaps, used animal models, and were in English. Studies were excluded if they did not use cells of human origin. The flap survival or necrotic area, perfusion, capillary density, vascular endothelial growth factor secretion and HIF-1α expression were extracted. Results: Ten studies met inclusion criteria. The mean absolute risk reduction (ARR) in necrotic skin area was 22.37% (95% confidence interval [CI] 16.98-27.76%, P<0.05) for flaps treated with animal ADSCs and 18.04% (95% CI 2.74-33.33%, P<0.05) for flaps treated with hADSCs. The difference between mean ARRs was not statistically significant (4.33%, 95% CI – 34.47-43.13%, P>0.05). Conclusion: Human ADSCs prevent skin flap necrosis to the same degree as animal ADSCs in rodent and rabbit flap models. Relevance for Patients: This review found that adipose-derived stem cells of human origin are equally effective at reducing the risk of surgical flap necrosis in preclinical models of small animals as autologous animal cells. The findings in this review should encourage researchers to use human adipose-derived stem cells in animal models of ischemic flaps to accelerate their translation into clinical trials and, eventually, surgical practice. The low immunogenicity of these cells should be leveraged to gain insight into the effects of the products that will be ultimately administered to patients. Furthermore, human adipose-derived stem cells’ pro-angiogenic mechanism of action sets this therapy as a promising preventive measure for flap necrosis.
A Modulated Feedback Approach to Improve Closed Loop MEMS Accelerometer Bias Instability

Bias instability serves as one important performance specification for MEMS accelerometer. The bias instability is affected by 1/f noise. Conventional operation adopts the correlated double sampling (CDS) to reduce the 1/f noise, but is only feasible with switch capacitors. The paper proposes a novel and universal modulated feedback approach to improve the bias instability of closed loop MEMS capacitive accelerometer. The modulated feedback method is utilized to isolate the 1/f noise the electronic interface brings to the system. The comparison experiments are set up and the Allan Variance show significant improvement for the bias instability. We achieve the bias instability around 8μg after applying modulated feedback approach, making the closed loop MEMS accelerometer being able to enter high precision inertial sensor level.
Depiction of Genomic Regions and Genes Related with Drought Tolerance in Sorghum [Sorghum bicolor (L.) Moench]

The study of quantitative trait loci (QTLs) can bridge the gap between traditional breeding procedures and more efficient genetic improvements. The study of quantitative trait loci (QTLs) can bridge the gap between traditional breeding procedures and more efficient genetic improvements. In this report, we assess progress in mapping quantitative trait loci and genes associated with drought resistance in sorghum. Drought avoidance is linked to a number of morphological and physiological adaptations, including limiting water loss and increasing water absorption. The effects of physiological parameters will be investigated in order to find certain selection criteria that could be relevant in the development of drought-tolerant genotypes. Drought avoidance is linked to a number of morphological and physiological adaptation traits, including In grain sorghum, quantitative trait loci affecting green retention are an important feature for post blooming drought tolerance that have been investigated in various situations and with various genetic backgrounds. The two QTLs remain green (Stg2 and Stg4) of B35 x Tx7000 RILs were entirely matched in both populations, according to QTL analysis performed in the two mapping populations of recombinant inbred lines (RILs). Investigation done on different 44 sorghum lines confirmed that four QTL root nodal root angle discovered in the mapping population. Significant marker–trait association’s delignated within the quantitative chromosome (CI) for root angle (qRA2_5, qRA1_8 and qRA1_10) or closely allied to root angle (qRA1_5). Post-flowering drought response is expressed in sorghum when moisture stress occurs during grain development (GS-3). Three QTLs were detected for flowering time on chromosomes 2, 6, and 9, with log odds values (LOD) ranging from 2.5 to 3.3 and explained phenotypic variance (PVE) values calculated from 6 to 11%.