Miracle-dz/UniFAR-FTUs huggingface dataset:
Immunohistochemical Distribution of Serotonin Transporter (SERT) in the Optic Lobe of the Honeybee, Apis mellifera

Simple Summary Serotonin is ubiquitously expressed in vertebrates and invertebrates, where it regulates specific behavioural patterns. Though the specific effects of serotonin release in the optic lobe are not entirely known, increasing evidence associates the serotonergic system with optic lobe-mediated behaviours. In this study, the localization of serotonin transporter (SERT) was immunohistochemically analysed in the optic lobes of moderate, docile and aggressive worker honeybees. SERT-immunoreactive fibres were stratified in the optic lobe and distributed in the three visual neuropils: lamina, medulla and lobula. Interestingly, SERT immunoreactivity was inversely related to aggressive behaviour. The present study indicates that low levels of serotonin in the optic lobe are associated with aggressive behaviour. Abstract Visual information is processed in the optic lobes, which consist of three retinotopic neuropils. These are the lamina, the medulla and the lobula. Biogenic amines play a crucial role in the control of insect responsiveness, and serotonin is clearly related to aggressiveness in invertebrates. Previous studies suggest that serotonin modulates aggression-related behaviours, possibly via alterations in optic lobe activity. The aim of this investigation was to immunohistochemically localize the distribution of serotonin transporter (SERT) in the optic lobe of moderate, docile and aggressive worker honeybees. SERT-immunoreactive fibres showed a wide distribution in the lamina, medulla and lobula; interestingly, the highest percentage of SERT immunoreactivity was observed across all the visual neuropils of the docile group. Although future research is needed to determine the relationship between the distribution of serotonin fibres in the honeybee brain and aggressive behaviours, our immunohistochemical study provides an anatomical basis supporting the role of serotonin in aggressive behaviour in the honeybee.
The potential for cascading wood from demolished buildings: Potential flows and possible applications through a case study in Finland

The aim of this study was to explore potential cascading flows and the measures that could be taken to enhance cascading potential. The results reveal that the potential cascading flow needs to be considered in light of the length and condition of the wood recovered from buildings, rather than the cross-section. For instance, wood in the roof structure such as ‘1 × 4’ or ‘1 × 6’ was recovered with most of the original length intact and with minimal damage, which is suitable for direct reuse. In contrast, wood in walls, floors and ceilings such as ‘2 × 2’, ‘2 × 3’ or ‘2 × 8’ was recovered in poor condition in terms of both length and the occurrence of damage. To enhance cascading potential, the development of the jointing systems and considering the reuse of whole elements of the unit parts should be further investigated.
Life Cycle Assessment on Agricultural Production: A Mini Review on Methodology, Application, and Challenges

Agricultural Life Cycle Assessment (LCA) is an effective tool for the quantitative evaluation and analysis of agricultural materials production and operation activities in various stages of the agricultural system. Based on the concept of life cycle, it comprehensively summarizes the impact of agriculture on the environment, which is an effective tool to promote the sustainability and green development of agriculture. In recent years, agricultural LCA has been widely used in the agroecosystem for resource and environmental impacts analysis. However, some challenges still exist in agricultural LCA, i.e., the environmental impact assessment index system needs to be improved; its application in different production mode is limited; and combination research with other models needs more attention. This paper discusses the above-mentioned challenges and recommends research priorities for both scientific development and improvements in practical implementation. In summary, further research is needed to construct a regional heterogeneity database and develop innovated methodologies to develop more meaningful functional units for agricultural products to complement LCA by other models. These efforts will make agricultural LCA more robust and effective in environmental impacts assessment to support decision making from individual farm to regional or (inter)national for the sustainable future of agriculture.
Salvage Post-Operative Stereotatic Ablative Radiotherapy for Re-Current Squamous Cell Carcinoma of Head and Neck

Background and Objectives: Patients with recurrent squamous cell carcinoma of the head and neck (rHNC) face an aggressive disease. Surgical resection is the gold standard treatment. Immediate adjuvant post-operative stereotactic ablative radiotherapy (PO-SABR) for rHNC is debatable. Materials and Methods: We retrospectively identified patients who were treated with PO-SABR at the AC Camargo Cancer Center, Brazil. Results: Eleven patients were treated between 2018 and 2021. The median time between salvage surgery and PO-SABR was 31 days (range, 25–42) and the median PO-SABR total dose was 40 Gy (range, 30–48 Gy). The 2-and 4-year actuarial DFS were 62.3% and 41.6%, while the 2-and 4-year OS probabilities were 80.0% and 53.3%, respectively. Eight (72.7%) patients were alive and six (54.5%) were without disease at the last follow-up. Two (18.1%) patients had local failure in the PO-SABR field. Three (27.3%) patients had distant metastasis, diagnosed in a median time of 9 months (range, 4–13) after completion of PO-SABR. On univariate analysis, predictive factors related to worse OS were: interval between previous radiotherapy and PO-SABR ≤ 24 months (p = 0.033) and location of the salvage target in the oral cavity (p = 0.013). The total dose of PO-SABR given in more than three fractions was marginally statistically significant, favoring the OS (p = 0.051). Conclusions: Our results encourage the use of a more aggressive approach in selected patients with rHNC by combining salvage surgery with immediate PO-SABRT, but this association needs to be further explored.
Effects of resveratrol therapy on glucose metabolism, insulin resistance, inflammation, and renal function in the elderly patients with type 2 diabetes mellitus: A randomized controlled clinical trial protocol

Background: Diabetes mellitus is a spectrum of metabolic disorders characterized by hyperglycemia and shows a growing global public health problem in the elderly. Resveratrol presents antiaging, anti-inflammatory, antitumor antioxidant, and cardioprotective activities. The purpose of this study was to investigate the ameliorative effects of resveratrol on blood glucose, insulin metabolism, lipid profile, renal function, inflammation, and nutrient sensing systems in the elderly patients with type 2 diabetes mellitus. Methods: The study is a single-blind, parallel-group, randomized controlled clinical trial consisting of a 6-month treatment period. A total of 472 elderly patients with type 2 diabetes mellitus were enrolled, and included participants will be randomized into 2 groups: resveratrol (n = 242) and placebo (n = 230). The clinical efficacy and changes in clinical parameters in each group will be measured at the indicated time. Clinical parameters included blood glucose, insulin resistance index, blood lipid index, proinflammatory cytokines, renal function, and nutrient sensing systems. Results: Resveratrol treatment greatly improved glucose metabolism, insulin tolerance, and insulin metabolism compared to placebo. Resveratrol relieved symptoms through enhancing nutrient sensing systems, which in turn reduced production and activity of glucose-6-phosphatase. Compared with placebo, resveratrol treatment significantly decreased proinflammatory cytokines glycated hemoglobin/hemoglobin A1c, interleukin-6, tumor necrosis factor-alpha, and interleukin-1beta in the elderly diabetes. Resveratrol treatment decreased blood glucose parameters, improved the lipid profile (total cholesterol, low-density lipoprotein, high-density lipoprotein, and triglycerides), and renal function compared to placebo. Conclusion: In conclusion, resveratrol treatment improves inflammation, renal function, blood glucose parameters, inflammation, insulin resistance, and nutrient sensing systems in the elderly patients with type 2 diabetes mellitus, indicating resveratrol may be a potential therapeutic drug for the treatment of the elderly patients with type 2 diabetes mellitus.
Insecticidal Effect of Cry Toxins Produced by Bacillus thuringiensis on Diceraeus melacanthus (Dallas, 1851) and Euschistus heros (Fabricius, 1798) (Hemiptera: Pentatomidae)

Some species of the Heteroptera (Hemiptera) suborder are of great agricultural importance, mainly as pests, and their control is often necessary. The use of Bacillus thuringiensis, an entomopathogenic bacterium normally extracted from the soil and used in biological control, is an alternative to the chemical control of these insects. Mortality tests must be carried out in order to select and determine a viable toxic strain, but currently there is no validated methodology for conducting those tests. In this context, this research aimed to develop and improve a selective bioassay methodology to assess the toxic effect of B. thuringiensis Cry toxins on Diceraeus melacanthus (green-belly stink bug) and Euschistus heros (neotropical brown stink bug) nymphs. A bioassay methodology consisting of tubes and artificial diet was proposed. Bioassays with D. melacanthus and E. heros nymphs were performed incorporating Cry toxins (Cry1Aa, Cry1Ab, Cry1Ac, Cry1B, Cry1C, Cry1F, Cry1G, Cry1Ia, Cry2Ab, Cry2A, Cry2Ae, Cry4A, Cry4B, Cry10, and Cry11Aa) into their liquid diet. The artificial feeding system developed in order to carry out the stink bug mortality tests was conducted. Among the toxins tested, we can highlight 2 causing 80-85% nymphal mortality on D. melacanthus, and 4 toxins causing 90-100% nymphal mortality for E. heros after 7 days of incubation. Both species are susceptible to different Cry toxins, with emphasis on Cry2Ab and Cry4B for D. melacanthus and Cry1B, Cry1G, Cry1Ia and Cry2Ab for E. heros.
Management of shoulder dystocia

723 Key points • Shoulder dystocia is a predominantly unpredictable and non-preventable event. • The progressive incidence of obesity and diabetes has determined the contemporary increase in shoulder dystocia incidence. • The main risk factors for shoulder dystocia are fetal macrosomia, diabetes mellitus, dystocia in the functional periods of labor and operative vaginal delivery. • Clinical imaging and pelvimetry are not helpful in identifying women at higher risk for shoulder dystocia. • Diagnosis and severity of shoulder dystocia are subjective. Failure of the head-shoulder maneuver and the turtle sign are the main diagnostic criteria. The need for multiple delivery maneuvers and the occurrence of maternal and/or neonatal injuries better evidence the severity of cases. • Professionals involved in childbirth care must be prepared to recognize shoulder dystocia and immediately perform a sequence of maneuvers for its correction in a timely manner. • Control of body weight and blood glucose levels is the main strategy likely to reduce the risk of shoulder dystocia. • The most common serious maternal complications of shoulder dystocia are postpartum hemorrhage and complicated perineal lacerations. • The most frequent neonatal complication of shoulder dystocia is transient brachial plexus palsy. • Skills training and simulation improve the care and documentation of shoulder dystocia, promoting evidence-based management and reducing transient brachial plexus injuries.
Farm Biosecurity and In uenza A virus detection in Swine Farms: A Comprehensive Study in Colombia

Ciuoderis-Aponte Karl (  coord_cwohc@unal.edu.co ) Universidad Nacional de Colombia sede Medellín. Consortium Colombia Wisconsin One Health Diaz Andres Pig Improvement Company Muskus Carlos Programa de Estudio y Control de Enfermedades TropicalesPECET, Universidad de Antioquia Mario Peña Asociación Porkcolombia Fondo nacional de la porcicultura Hernández-Ortiz Juan Universidad Nacional de Colombia sede Medellín. Consortium Colombia Wisconsin One Health Osorio Jorge University of Wisconsin–Madison
Hoisting Machine Brake Linkage Strain Analysis

The brake linkage of a hoisting machine is a very important component determining the safety of the hoisting machine’s entire braking system. It is subject to weekly inspections. However, an efficiency test of brake performance is carried out every 6 months. Once every 3 years, a test must be carried out by an appraiser who pays particular attention to the executive and control components of the brakes as well as the strain - brake system and brake release components. The legal provisions regulating the testing of braking system linkages are not precise. So far, the control has been based on random measurement of strains using electrical resistance strain gauges stuck to the surface of the linkage. A new method for measuring the strains of the linkage has been proposed in the work. It is based on fibre optic strain sensors with Fibre Bragg Gratings (FBG). They are mounted using specially designed and tested holders for mounting on the brake linkage. They provide quick assembly and the measurement of strain in the direction parallel to the axis of the linkage. The structure of the holder also allows for the measurement in 4 positions turned every 90 relative to one another. Such a measurement enables a comprehensive analysis of strains and stresses in the brake linkage. In the work, it was shown that there is a complex state of strain and stress in the brake linkage. The previous procedures for linkage testing are inadequate in relation to this condition. An experimental and numerical method was proposed to assess the state of linkage stress. It should constitute the basis for the decision of the appraiser to allow the linkage for further use. The method proposed in the work also allows for continuous measurements of linkage strains as well as dynamic braking tests.
The Pros And Cons Of Morning And Evening Exercise A Review Article

:-Evidence suggests that exercise may contribute to prevent pathological changes, treating multiple chronic diseases, and reducing mortality and morbidity ratio. Scientific evidence moreover shows that exercise plays a key role in improving health related physical fitness components and hormone functions. Regular exercise is one of the few strategies that have been strictly adapted by healthy individuals for fitness. However, time-dependent exercise has different outcomes, which are also mainly based on the type of exercise, duration and hormone adaption etc. In the present review, we briefly describe the type and duration of exercise performed in morning and evening. In addition to this context, we discuss the pros (advantages) and cons (disadvantages} of the best and suitable time of day for exercise, for getting maximum benefits out of it.
Resource-effective exploration of tumor treatments with multi-scale simulations

Machine learning is regularly used to interpret and analyze information from large and complex datasets originating from numerous fields. In Bioinformatics, the exploration of potentially beneficial drug configurations for tumor treatments via simulations requires multiple processing units to be used in parallel and a considerable amount of time to be completed. In this paper, we apply a state-of-the-art model exploration workflow for the characterization of a new drug configuration parameter space, using a redesigned simulator. Moreover, we incorporate different clustering and optimization approaches and compare their performance in in-silico simulation trials on high-performance computing infrastructure, with respect to time and resource efficiency. The overall goal is to discover regions in this parameter space that can lead to more viable treatments in reasonable time, and thus guide the related research towards more focused and effective real-world trials.
The Impact of Stress and Health on Quality of Working Life of Women in SMEs in Republic of Serbia

This paper gives analysis of impact of stress and health on quality of life of female workers in small and medium enterprises in Republic of Serbia. Research was conducted via questionnaire which held statementss regarding stress, health and quality of life, and was distributed to female workers in small and medium enterprises. Research results based on proposed model prove that stress and health have significant impact on overall quality of working life and that by altering each one of the variables mentioned or both at once level of quality of working life of female workers changes. Total of 198 respondents contributed to this research from all business positions.
Innovative modular and arrayed coil systems for ultrahigh efficiency in inductive heating and automated metal detection

INNOVATIVE MODULAR AND ARRAYED COIL SYSTEMS FOR ULTRAHIGH EFFICIENCY IN INDUCTIVE HEATING AND AUTOMATED METAL DETECTION Veli Tayfun Kılıç Ph.D. in Electrical and Electronics Engineering Advisor: Hilmi Volkan Demir December 2016 Induction systems have become increasingly more important and popular in our modern world and their application areas have widely expanded because of their high levels of safety and controllability. Today one important application of these induction systems is the inductive heating, which now finds use not only in conventional applications of point-source heating but also in new areas including all-surface heating with some degree of flexibility in localization. The efficiency of such emerging systems, especially in planar structures across an entire surface, however, has thus far been limited compared to conventional inductive heating. In this thesis, to address these problems, we show a new class of strongly coupled planar coils that enhance magnetic coupling in square lattice stacking by design and with phase difference application in operation. These coils can be tiled in two-dimensional arrays in a modular fashion or to cover an arbitrarily large continuous surface. In a proof-of-concept realization, we experimentally demonstrated that these proposed outer squircle-inner circular coils outperform the conventional coils of circular shape. Using square-arrayed coil architecture, here we also present all-surface induction systems achieving uniform and enhanced heating speed for all loading positions no matter what the misalignment of the heated vessel with respect to the coils is. In addition, to solve the problems of automatically detecting metals over the whole surface together with determining their exact positions, we introduce a new method that relies on simultaneous wireless measurement and tracking of inductance-resistance of the coils at multiple frequencies to identify those coupled with the metal targets to be detected in the system. While pinpointing the location of the targeted metals, the proposed technique also identifies their material types. For future ubiquitous all-surface systems, this approach allows for automated sensing of metal vessels and powering the loaded coils for the highest possible performance independent of the
Ambienizer: Turning Digital Photos into Ambient Visualizations

The Ambienizer is a visual encoding approach that seeks to convey a user’s personal data in a casual non-technical way. In the Ambienizer, a user can choose any image and map any of the provided image processing techniques to the variables from personal data. In this work, we use the Ambienizer in the context of monitoring household energy use. We allow the user to compare the user’s energy consumption with a social norm, a past consumption, or a targeted consumption.
Anatomy-based Optical Motion Capture for Integral Joint Motion Visualization and Analysis

We propose a methodology to improve the accuracy of joint motions optical acquisition and enhance the visualization of the virtually replicated motion for biomedical applications. The joint of the subject is reconstructed from medical images including the 3D shapes of the bones and kinematical data such as the joint center for motion simulation. The subject visualization model is built by inserting the reconstructed joint inside an H-ANIM model fitted to the real measurements of the subject. Finally, the visualization model is calibrated and the captured motion mapped onto the anatomical visualization model. This methodology provides a subject-fair visualization model for optical motion capture based on the morphology and anatomy of the volunteer so that the motion simulated from the subject is closer to the real situation. It also provides an integral visualization of joint motion by correlating the external motion of the subject is moving with the internal motion of the joint.
One-Handed Recessed Mount for Fixed Dome Cameras

This master thesis report describes a product development process with the aim to extend the existing range of mounts for surveillance cameras mounted recessed in ceilings. A recessed mount is an accessory for mounting cameras, or other devices, in ceilings when a discreet finish is wanted. The goal was to design a solution that can be mounted fast, easy and with the use of one hand only. The company at which this project has been performed is Axis Communications AB, who is market leading in network cameras. A thorough background study was performed in order to acquire knowledge about the issues arising when mounting cameras recessed in the ceiling and what techniques are being used on products available on the market today. The result of the background study showed that two techniques are most common; using metal spring torsions, like what is used when mounting spotlights, or with a technique that requires screws and consequently tools which takes time. The work resulted in a concept consisting of two main parts, a housing and a handle, and three parts aiming to connect the main parts. The handle and the housing are pressed together when the recessed mount is inserted in a hole in the ceiling which forces the arms connected to the handle outwards and the camera unit can then be mounted to the recessed mount. One important feature of the handle are the two living hinges that connects the arms to the handle. The living hinges have limited loadbearing capacity and are the critical point of the design and needs further testing to ensure the functionality. This thesis work proves that a solution that offers one-handed and fast mounting of a recessed mount is possible.