Miracle-dz/UniFAR-FTUs huggingface dataset:
Child Psychiatry: A Developmental Approach

Part 1 Overview: assessment family influences and parenting disturbances. Part 2 Development and its disorders: foetal and infant development feeding and eating control disorders sleep and its disorders motor development and disorders of movement language and its disorders intelligence and learning disorders emotional development and disorders of mood later social development sensory development sphincter control sexual development personality development. Part 3 Adult-type psychiatric disorders: psychoses neurotic, somatoform and stress-related disorders drug and alcohol use and abuse child-adult - continuities in psychiatric disorders. Part 4 Psychosocial aspects of physical disorders - general: impact on parents, the child, the sibs principles of psychosocial management of physically handicapped children and their families hospitalization care of the dying child. Part 5 Psychosocial aspects of specific physical conditions: stillbirth and neonatal death sudden infant death syndrome (cot death) chromosomal abnormalities malformations injuries to children infectious diseases disorders of the central nervous system and muscle metabolic disorders endocrine disorders blood disorders respiratory disorders genitourinary disorders disorders of the alimentary tract congenital heart disease skin disorders immunodeficiency disorders juvenile chronic arthritis. Part 6 Prevention and treatment. Part 7 Services: primary and secondary health care mental health services for children social welfare services and child protection school influences and special education.
Geological characteristics and prospecting mark of the Baishan porphyry Mo deposit, East Tianshan

The Baishan Mo deposit is the first porphyry (quartz stockwork) Mo deposit of fairly large magnitude found in the Kanggur-Tuwu-Chihu-Huangshan metallogenic belt on the southern side of the eastern segment of the Kanggur ductile shear zone in the East Tianshan Mountains. It occurs in the biotite felsic hornstone zone of the Lower Carboniferous Gandun Formation and granite porphyry vein. The host rocks consist predominantly of K-feldspar-quartz veinlets, sulfide veinlets and felsic hornstone. The Mo orebodies are mainly stratified in shape, 100-2000 m long with an average thickness of 2.31-43.9 m. The Mo grade ranges from 0.030%-0.106%, with a mean grade of 0.06% in the ore district. The orebodies thickness is big and have a relatively persistent downward extension. From the center outward, four alteration zones, the K-feldspar-quartz stockwork zone, biotite-quartz-K-feldspar alteration zone, quartz-sericite alteration and propylitic alteration zone, may be distinguished. Mo orebodies formed in sites where K-feldspar-quartz stockworks are very well developed. Furthermore, this deposit is correlated with some typical porphyry Mo deposits in respect to the geomorphology, remote sensing features, geochemistry, structure, rocks and alteration and some criteria for Mo prospecting in the Baishan Mo deposit are summarized.
Aided parameter selection for dimensionality reduction Project proposal

In this paper, a tool is evaluated to help users find optimal low-dimensional embeddings of highdimensional datasets. Two datasets are analysed using this tool. One is the well known COIL-20 dataset, the other is new dataset containing milkproduction data of an Automatic Milking System. We propose a tool that allows easy selection of dimensionality reduction algorithm, parameters and resulting dimensionality, and allows integrated interactive visualization of the results. Two dimensionality reduction methods are currently available in the tool. The first is Principal Component Analysis, a commonly used linear method. The second is Locally Linear Embedding, a more recent nonlinear dimensionality reduction method. Quality of the resulting embedding is evaluated externally to the program by using a logistic classifier. Intuitive visual evaluation of a low dimensional embedding of a dataset is shown to give a good indication of the performance of the dataset in a classifier.
Consideration and practice of the construction of litho stratigraphic systems in high-grade metamorphic terrains -Acase study in the Daqingshan-Wulashan area

The early Precambrian stratigraphic system in the Daqingshan-Wulashan area is reconstructed based on recent regional geological survey. A Meidaizhao Group-complex is eslatlished and classified as the Paleoproterozoic. The high-grade metamorphic rocks in the area are regrouped, i.e. the granulite sequence is subdivided into two formation complexes, which are merged into the Sanggan Group-complex, and the Wulashan Group-complex is subdivided into two subgroup-complex, a lower subgroup complex. and an upper subgroup complex.The former is known as the gneiss sequence and the latter is equivalent to the Jining Group, a khondalite sequence. The major structural patterns of the high-grade terrain in the area are characterized by dome structures and fold groups between the domes (simply called `dome-fold' structures). It is suggested that the large-scale ledding detachment system is a key factor for determining the spatial distrilution,composition and interrelations of high-grade metamorphic rocks.The new ways and methods of estallishing lithostatigraphic systems in high-grade metamorphic terrains are proposed in the paper.
Analisis Trend Hujan Di Bandaraya Ipoh Perak 1970-2007

Penelitian terhadap trend hujan jangkamasa panjang adalah penting dan relevan dalam kajian hidrologi khususnya sebagai alat untuk mengesan dan mengenalpasti perubahan yang berlaku dalam sistem hidrologi. Untuk itu, data hujan bulanan dan tahunan dari tahun 1970 hingga 2007 yang diperolehi daripada Jabatan Meteorologi Malaysia dianalisis dengan menggunakan ujian statistik dan Ujian Mann-Kendall bagi mengesan perubahan (meningkat, menurun atau stabil) atau trend yang berlaku. Dapatan kajian menunjukkan trend hujan tahunan meningkat dari tahun 1970-2007 dengan purata tahunan 2497 mm. Rekod juga menunjukkan bahawa trend hujan yang meningkat semasa Monsun Timur Laut dan Monsun Barat Daya dalam tempoh yang sama. Hujan maksimum adalah pada bulan April dan Oktober iaitu semasa berlakunya pertukaran monsun. Rekod juga menunjukkan kawasan Ipoh menerima hujan paling banyak semasa Monsun Timur Laut walaupun stesen hujan terletak di sebelah pantai barat Semenanjung Malaysia dengan purata 1016 mm. Hujan bulanan dari tahun 1970-2007 menunjukkan kepelbagaian variasi. Berdasarkan Ujian Mann-Kendall (S), bulan Mei (-21), September (-25), Oktober (-35) dan Disember (-16) menunjukkan trend yang menurun dan bulan-bulan lain menunjukkan trend yang meningkat. Keadaan ini jelas menunjukkan variasi hujan yang kompleks di kawasan tropika. Faktor perubahan iklim global masa kini serta hidrometeorologi tempatan dijangka mempengaruhi trend hujan serta perubahan guna tanah khususnya aktiviti perbandaran yang wujud di bahagian tengah lembangan Kinta iaitu di Bandaraya Ipoh.
Analysis on water pollution trends and treatment technologies of the Beiyunhe basin Beijing reach

Based on the status of water pollution and hydor-ecosystem, together with the yearly variation of water quali-ty, the water pollution trends and environment problems in the Beiyunhe Basin Beijing reach were analyzed at the end of the 11th five-year-plan. Aiming at the problems, some treatment technologies such as upgrading process for town wastewater treatment plants, rural non-point source pollution control and river ecological restoration system, were pre-sented to be studied in the 12th five-year-plan. Only in this way can we support water pollution reduction and sustain-able development in this basin.
[Brugada syndrome].

Background. Brugada syndrome was first described in 1992. Initially it was regarded as an electrocardiographic curiosity, but in recent years the syndrome has been subject to great activity in both clinical investigation and basic science due to its association with a high risk of sudden death in young and otherwise healthy individuals. The syndrome is an hereditary arrhythmogenic disease characterised by an ECG pattern with ST-segment elevation in the right precordial leads (V1 – V3), and an increased risk of polymorphic ventricular tachycardia and ventricular fibrillation. The pattern of inheritance is autosomal dominant and a mutation has been identified in only 20–30 % of patients with Brugada syndrome.
Strategy formulation for the recreational areas of central Taiwan: an application of SWOT (strengths, weaknesses, opportunities, threats) analysis.

Recreational areas are economically beneficial and can directly assist both local communities and nations in achieving sustainable environmental development. This study combines analytic hierarchy process (AHP) with the SWOT (strengths, weaknesses, opportunities, threats) method to construct a quantifiable SWOT model to assess strategy formulation for nine recreational areas in central Taiwan. The fuzzy Delphi method determined the assessment criteria indicators, while the relative weights of these criteria were examined by the AHP. An expert questionnaire including these criteria was designed to assess the performance of the recreational areas. In the SWOT model, the relative performance among different recreational areas was parameterized specifically. The analytical results provide valuable quantitative data for developing and implementing current enterprises strategy. The focus of this work is on providing useful quantitative information, to assess the competitiveness different recreational areas, for developing and implementing strategy. Key words: Analytic hierarchy process (AHP), fuzzy Delphi method, recreational area, SWOT (strengths, weaknesses, opportunities, threats), Taiwan.
UvA-DARE (Digital Academic Repository) Efficacy of a Mindfulness-Based Mobile Application: a Randomized Waiting-List Controlled Trial

Although several hundreds of apps are available that (cl)aim to promote mindfulness, only a few methodologically sound studies have evaluated the efficacy of these apps. This randomized waiting-list controlled trial therefore tested the hypothesis that one such app (the VGZ Mindfulness Coach ) can achieve immediate and long-term improvements of mindfulness, quality of life, general psychiatric symptoms, and self-actualization. One hundred ninety-one experimental participants received the VGZ Mindfulness Coach, which offers 40 mindfulness exercises and background information about mindfulness without any form of therapeutic guidance. Compared to 186 control participants, they reported large (Cohen ’ s d = 0.77) and statistically significant increases of mindfulness after 8 weeks and small-to-medium increases of the Observing, Describing, Acting with awareness, Nonjudging, and Nonreactivity mindfulness facets as measured with the Five Facet Mindfulness Questionnaire (Cohen ’ s d = 0.66, 0.26, 0.49, 0.34, and 0.43, respectively). Also, there were large decreases of general psychiatric symptoms (GHQ-12; Cohen ’ s d = − 0.68) and moderate increases of psychological, social, and environmental quality of life (WHOQOL-BREF; Cohen ’ s d = 0.38, 0.38, and 0.36, respectively). Except for social quality of life, these gains were maintained for at least 3 months. We conclude that it is possible to achieve durable positive effects on mindfulness, general psychiatric symptoms, and several aspects of quality of life at low costs with smartphone apps for mindfulness such as the VGZ Mindfulness Coach
Identification of Night-Time F-Region Currents from CHAMP Satellite Observations over Equatorial Africa

The F-region currents are generally weak and difficult to detect. However, their contributions to the earth’s magnetic field variations are significant and cannot be ignored by the field modelers. CHAMP satellite has therefore provided a perfect opportunity to investigate the in-situ F-region currents on the night side of the equatorial region. The magnitudes of the current along all the three components of the earth’s magnetic field (X, Y, Z) are investigated. However in this paper, we present only the results on the Y-component where interesting magnetic residuals were observed. The X and Z-components were rather masked in much noise and would require further filtering. The currents appear in both the pre-midnight and postmidnight sectors and are spatially confined to the equatorial region bounded by the Appleton anomaly. The magnetic residuals are generally observed in the northern hemisphere of an order of 0.8nT, which gives a height-integrated current density of about 1.3mA/m.
Design, synthesis, biological evaluation and molecular docking study of novel pleuromutilin derivatives containing substituted benzoxazole as antibacterial agents

Abstract A series of pleuromutilin analogs containing substituted benzoxazole were designed, synthesised, and assessed for their antibacterial activity both in vivo and in vitro. The MIC of the synthesised derivatives was initially assessed using the broth dilution method against four strains of Staphylococcus aureus (MRSA ATCC 43300, S. aureus ATCC 29213, clinical isolation of S. aureus AD3 and S. aureus 144). Most of the synthesised derivatives displayed prominent in vitro activity (MIC ≤ 0.5 µg/mL). Compounds 50 and 57 exhibited the most effective antibacterial effect against MRSA (MIC = 0.125 µg/mL). Furthermore, the time-kill curves showed that compounds 50 and 57 had a certain inhibitory effect against MRSA in vitro. The in vivo antibacterial activity of compound 50 was evaluated further using a murine thigh model infected with MRSA (–1.24 log10CFU/mL). Compound 50 exhibited superior antibacterial efficacy to tiamulin. It was also found that compound 50 did not display significant inhibitory effect on the proliferation of RAW 264.7 cells. Molecular docking study revealed that compound 50 can effectively bind to the active site of the 50S ribosome (the binding free energy −7.50 kcal/mol). GRAPHICAL ABSTRACT
Analysis of Clinical Characteristics and Gene Variants Associated with Primary Ciliary Dyskinesia

Background: Primary ciliary dyskinesia (PCD) is considered a monogenic heterogeneous recessive disorder. Objectives: This study aimed to identify clinical characteristics and gene mutations in children with PCD admitted to Quanzhou Women’s and Children’s hospital in China from January 2019 to January 2022. Methods: Clinical manifestations, lung imaging, transmission electron microscopy (TEM) findings, and genetic test results were analyzed in this study. Results: For 8 patients, PCD manifestations included asthma, total visceral inversion, secretory otitis media, adenoid hypertrophy, gastroesophageal reflux, intestinal malrotation with midgut torsion, and bronchiectasis. Primary ciliary dyskinesia-associated gene variants included DNAH11, DNAH5, RSPH4A, and CFAP300. Novel variants of DNAH11 (c.5460 + 5G > C, c.117499_11752delGTTA, and c.5822G > C), DNAH5 (c.4314delT and c.877dupA), RSPH4A (c.1774_1775delTT and c.1949A > G), and CFAP300 (c.603delG) were found in these children. Conclusions: Recurrent cough, expectoration, purulent discharge, bronchiectasis, and visceral inversion provide clues for diagnosing early-onset PCD. Transmission electron microscopy and genetic testing improve early diagnosis, treatment delivery, and prognosis. Novel genotypes identified in this study expand the PCD genotypic spectrum.
A Predicative Analysis of the Grain Demand in the Nine Major Chinese River Basins in the 21st Century

As China is the largest populated country and her arable land is relatively small, the irrigation is decisive for the food yield. All this forecasts a premise of food demand in the future. Therefore, this paper simulates the grain (wheat, rice, and maize) demand in China, in particular, from the nine major Chinese river basins in 2010 and 2020 respectively, by the two models of CAPSIM and PODIUM, and by a comprehensive database at different national levels. The result shows that as the growth of population and income, food or fodder consumption will grow also. Thus, the tradable grain demand will increase by 25% in 2025 than 2000, with the average food consumption slowly decreasing but fodder, such as maize consumption quickly increasing.
An Analytic Approach to Climate Dynamics and Fire Frequency in the Great Plains

<p>Long-term knowledge of fire regimes aids in understanding the past, present, and future changes in Great Plains ecosystems. Dated fire scar histories and fire rate metrics in the Great Plains allow for quantitative analysis of the effects of climate on fire occurrence, frequency, forcing factors, and probability. Up to three centuries of fire scar data combined with modeling results from Great Plains sites show that spatially, fire frequency was greatly affected by annual maximum temperature from north to south, by annual precipitation east to west, by their interactions, and by precipitation thresholds. A fire-climate model, <small class="caps" xmlns:m="http://www.w3. org/1998/Math/MathML" xmlns:mml="http://www.w3. org/1998/Math/MathML" xmlns:xlink="http://www.w3. org/1999/xlink">pc </small>2<small class="caps" xmlns:m="http://www.w3. org/1998/Math/MathML" xmlns:mml="http://www.w3. org/1998/Math/MathML" xmlns:xlink="http://www.w3. org/1999/xlink">fm </small> (Physical Chemistry Fire Frequency Model), calibrated with rate metrics (mean fire intervals) derived from fire history data, estimates that in the Great Plains, fire intervals ranged from <4 to > 30 years. A “precipitation threshold” divides the Great Plains into eastern and western fire regime regions along an approximate 60–100 cm north-south annual precipitation isohyet. Future changes in annual wildland fire probability at 1.2 km<sup xmlns:m="http://www.w3. org/1998/Math/MathML" xmlns:mml="http://www.w3. org/1998/Math/MathML" xmlns:xlink="http://www.w3. org/1999/xlink">2</sup> are predicted to change from –10% to 70% in the Great Plains. Midlatitude regions of the Great Plains (Wyoming, eastern Colorado, Nebraska, Kansas, and South Dakota) are expected to increase the most in annual fire probability while some areas in Texas will decrease in fire probability due to fuel limitations. </p>
Oskarshamn site investigation Bedrock mapping 2004 - Laxemar subarea and regional model area Outcrop data and description of rock types

This project presents an outcrop database for the Laxemar subarea and its immediate surroundings as well as for selected parts of the regional model area. At a later stage, the outcrop database will be evaluated and integrated with results from geochemical and mineralogical analysis of rock samples and geophysical data, in order to generate a bedrock map at scale 1:10,000 for the Laxemar-subarea and its immediate surroundings. A total of 1,350 outcrop observation points have been documented. Out of these observation points, 1,169 are within Laxemar subarea and its immediate surroundings and 181 are within the remaining part of regional model area. The bedrock information that was documented in the selected areas outside the Laxemar subarea and its immediate surroundings, demonstrates that the model version 0 bedrock map, with respect to the scale in which it originally was compiled (1:100,000), reasonably well reflects the extension of different rock types. However, significant discrepancies from the version 0 bedrock map were observed locally. The scattered bedrock information, including the documented discrepancies, that has been gained outside the Laxemar subarea and its immediate surroundings is to sparse to form the basis for an updated version of the version 0 bedrock map to the scale 1:50,000 in the overall regional model area.
Environmental Mapping Automation by Quadruped Robot Using Lidar Technology

Navigation as well as mapping using robots is currently widely used in various fields. Automated robot navigation and mapping allows robots to provide information about their surroundings to humans more effectively. LiDAR is one of the latest technologies used to carry out environmental mapping. The implementation of LiDAR technology coupled with legged robots is useful for autonomously mapping environments that have uneven trajectories, such as on the ground, rocky areas, and grass. Quadruped robot is a type of legged robot that is used in research and operations in the industrial world or in observing certain environmental areas. Determining the appropriate gait according to the observed characteristics of the robot and the environment, selecting the algorithm for mapping, and presenting the visualization of the map must be met for the success of the mapping process. This research applies Hector SLAM, crawl gait, trot gait, and the use of LiDAR technology to map the artificial environment which is carried out autonomously by a quadruped robot with the aim of obtaining information in the form of an environmental map which is visualized using RViz. The implementation of crawl gait to move forward is considered the most suitable for the quadruped robot in this research because the load being lifted is quite heavy, namely ±1.5kg, while the implementation of a dynamic trot gait is used to turn left or right. The result of this research is that the quadruped robot is able to walk through a well-defined environment and draw a complete map of the observed artificial environment with an accuracy rate of 97%.
Successful change of treatment strategy in elderly patients with primary central nervous system lymphoma by de-escalating induction and introducing temozolomide maintenance

lymphomas (DLBCL) and it was previously shown that the addition of rituximab to CHOP chemotherapy has improved the prognosis in DLBCL outside the brain. 2) The intraventricular MTX/cytarabine treatment of the Bonn protocol requiring an Ommaya reservoir was replaced by intraspinal administration of liposomal cytarabine in view of the expected lower risk of procedure-related infections. 3) The infusion time of MTX was reduced from 24 h to 3 h as a higher drug penetration has been achieved by a shorter infusion time. 4) Importantly, given the cited literature, the treatment was age-adjusted with patients aged over 65 years having cyclophosphamide of the second and fifth and ifosfamide of the fourth chemotherapy cycle replaced by the less toxic agent temozolomide (TZM). Vincristine was also not part of the study treatment for the elderly patients. 5) To improve disease control in responding patients aged over 65 years in whom induction intensity was reduced, maintenance treatment with TZM was added. This was done because TZM, an oral alkylating agent, can penetrate the intact blood brain barrier, and because it has shown activity and a favorable toxicity profile in PCNSL patients.