Miracle-dz/UniFAR-FTUs huggingface dataset:
Metode identifikacije goveđeg mesa iz pašnog uzgoja

Meso dobiveno od goveda hranjenih voluminoznim krmivima, odnosno, na paši premium je proizvod, poboljšanih nutritivnih i osjetilnih karakteristika. Navedeno je potaknulo i veliko zanimanje za metode identifikacije i provjere autentičnosti kojima se garantiraju tvrdnje o podrijetlu takvog mesa. Ovaj rad daje pregled trenutnih saznanja o identifikaciji autentičnosti mesa goveda hranjenih, dominantno travama, odnosno, pašnim načinom proizvodnje. Razvijen je niz analitičkih metoda, samih ili kombiniranih, koje uključuju analize elementarnih ili molekularnih sastojaka animalnih proizvoda i u kombinaciji s kemometrijom, koji su se pokazali korisnima za razlikovanje različitih sistema hranidbe uz provjeru autentičnosti mesa goveda držanih na pašnjacima. Neke od ovih analiza uključuju određivanje sastava masnih kiselina, hlapljivih i fenolnih spojeva, karotenoida, stereoizomera vitamina E, omjera stabilnih izotopa, proteinskih markera i drugih bioaktivnih spojeva. Opisana je primjena spektroskopskih metode u identifikaciji podrijetla goveđeg mesa, te suvremena funkcionalna genomika, kao jedan od najnovijih pristupa u identifikaciji mesa proizvedenog na paši. Njihova identifikacijska pouzdanost u složenijim uvjetima hranjenja, kao što su promjene u dostupnosti krmiva i/ili kada paša čini samo dio hranidbe životinje i dalje se nadgrađuju i aktivno se istražuju. Opisuju se metode kroz njihove mogućnosti i potencijalna ograničenja, a što je najčešće uzrokovano varijacijama u količini, karakteristikama i sastavu hrane s pašnjaka koju konzumiraju životinje, a koje su ipak svojstvene sustavima proizvodnje na travnjacima, varijacijama u reakcijama životinja unutar i između pasmina i poteškoće u otkrivanju konzumacije hrane koja nije trava od strane životinje. Također, ističe niz pitanja za razmatranje, točke opreza i upozorenja u primjeni ovih metoda. Provjera autentičnosti životinja, povijest hranidbe kroz životinjske proizvode, a posebno provjera autentičnosti mesa od životinja hranjenih travom, suočava se s izazovima svojstveno praksama u uzgoju stoke, uglavnom zbog varijacija u sastavu obroka i varijacijama tijekom proizvodnog života. Velik dio dosadašnjih istraživanja bavio se dokazivanjem sistema identifikacije proizvoda, dok bi se budućnosti trebalo uložiti više resursa za razvoj baza podataka kako bi se stekla jednostavnost primjene i sigurnost sustava kontrole animalnih proizvoda.
Biosafety evaluation of Carica papaya aqueous leaf extract on haematological parameters and organ/body weight ratio in Wistar rats.

Carica papaya L. (Caricaceae) is an herbaceous perennial tree crop commonly cultivated for its ripe edible fruit. Locally, the leaf decoction is used for treatment of malaria. This study investigated acute toxicity and sub-acute biosafety of C. papaya aqueous leaf extract on haematological and organ/body weight indices. Matured fresh C. papaya leaves were collected, dried and pulverized before extraction using aqueous decoction technique. The liquid extract was further concentrated to dryness and kept in an air tight bottle until further use. Acute toxicity in mice was appraised according to the method of Lorke, while sub-acute toxicity was determined by assessing haematological and organ/body weight parameters in four groups of Wistar rats pre-treated as follows: Group I (control) received distilled water (ml/kg body weight), while groups II, III and IV were administered single daily doses of 200 mg/kg, 400 mg/kg and 800 mg/kg of the extract for 28 consecutive days. The result from the acute toxicity studies was assessed to be above 5000 mg/kg, while the 28 days sub-acute test revealed that there was no significant difference, P> 0.05, in all haematological parameters and organ/body weight ratios evaluated when compared with the control. This study revealed that orally administered C. papaya aqueous leaf extract was tolerated at a single high dose, LD50 above 5000 mg/kg. Also, repeated administration of the test doses did not adversely interfere with any haematological parameter as well as organ/body weight profiles evaluated. The data obtained tend to support the biosafety of the plant extract as reportedly used in herbal home remedies.
Exploring order in active turbulence: Geometric rule and pairing order transition in confined bacterial vortices

Ordered collective motion emerges in a group of autonomously motile elements (known as active matter) as their density increases. Microswimmers, such as swimming bacteria, have been extensively studied in physics and biology. A dense suspension of bacteria forms seemingly chaotic turbulence in viscous fluids. Interestingly, this active turbulence driven by bacteria can form a hidden ensemble of many vortices. Understanding the active turbulence in a bacterial suspension can provide physical principles for pattern formation and insight into the instability underlying biological phenomena. This review presents recent findings regarding ordered structures causing active turbulence and discusses a physical approach for controlling active turbulence via geometric confinement. When the active matter is confined in a compartment with a size comparable to the correlation length of the collective motion, vortex-like rotation appears, and the vortex pairing order is indicated by the patterns of interacting vortices. Additionally, we outline the design principle for controlling collective motions via the geometric rule of the vortex pairing, which may advance engineering microdevices driven by a group of active matter. This article is an extended version of the Japanese article, Ordered Structure and Geometric Control of Active Matter in Dense Bacterial Suspensions, published in SEIBUTSU BUTSURI Vol. 60, p. 13–18 (2020).
Numerical and experimental analysis of vibratory signals for rolling bearing fault diagnosis

The detecting technique of the mechanical anomaly has been a hot topic in the scientific and engineering community. Vibration analysis has been frequently applied in the condition monitoring and fault diagnosis of rolling element bearings. Unfortunately, the vibration signals collected from a faulty bearing are generally nonstationary, nonlinear and with strong noise interference, so it is essential to obtain the fault features correctly. In this paper, a novel numerical analysis method that combines the singular value decomposition (SVD) and local mean decomposition (LMD) is proposed. SVD is a non-parametric technique which has been widely used to eliminate the noise and enhance the impulsive features, then LMD decompose the purified signal into a series of product functions (PFs), each of which is the product of an envelope signal and a purely frequency modulated FM signal. The envelope of a PF is the instantaneous amplitude (IA) and the derivative of the unwrapped phase of a purely flat frequency demodulated (FM) signal is the IF. After that the fault characteristic frequency of the roller bearing can be extracted by performing spectrum analysis to the instantaneous amplitude of PF component containing dominant fault information. Finally, the proposed method is applied to experimental data and the results show the effectiveness of the proposed technique in fault detection and diagnosis of rolling element bearing. DOI: http://dx.doi. org/10.5755/j01.mech. 22.3. 11962
Blood pressure variability in individuals with diabetes mellitus: a scoping review

ABSTRACT Objectives: to map methods and devices used to assess very short-, short-, medium-, and long-term pressure variability in adults with type 1 or 2 diabetes mellitus. Methods: scoping review conducted in January and February 2021 in MEDLINE, Web of Science, CINAHL, LILACS, PubMed, and Embase databases. Studies conducted within the last ten years analyzing pressure variability in adult and older patients with diabetes mellitus type 1 or 2 were included. Studies that used discontinued devices were excluded. Results: the sample was composed of 25 articles published since 2017, with the majority developed in Japan (n=11); with the predominance of the oscillometric method (n=22); the most used devices were from the Omron® brand (n=14); the most detected type was long-term variability (n=10). Conclusions: we observed the increasing application of the oscillometric method for pressure variability analysis with various brands and models of automatic devices.
The Underlying Physicochemical Properties and Starch Structures of indica Rice Grains with Translucent Endosperms under Low-Moisture Conditions

Rice grain quality is a complex trait that includes processing, appearance, eating, cooking, and nutrition components. The amylose content (AC) in the rice endosperm affects the eating and cooking quality along with the appearance of milled rice. In this study, four indica rice varieties with different ACs were used to study the factors affecting endosperm transparency along with the physical and chemical characteristics and eating quality of translucent endosperm varieties. Endosperm transparency was positively correlated with water content and negatively correlated with the cumulative area of cavities within starch granules. The indica landrace 28Zhan had a translucent endosperm and exhibited good taste. Based on starch fine structure analysis, long-chain amylopectin and the B2 chain of amylopectin might be major contributors to the good taste and relatively slow digestion of this landrace.
THE MEASURES AND REGULATIONS ABOUT WASTE EXPORTING

With the development of technology and industry, people could easily supply any of tools to make easier their life. Moreover, they would like to possess more technologic ones. As a result of this, there are always too many old and useless tools which called wastes anymore. As well as this, companies, countries, factories and any other organizations are also act in the same way. Consequently, all of these behaviors cause the waste problems. Furthermore, countries ,particularly rich and developed ones, try to remove these wastes without paying any cost and facing legal regulations. For that reason, they tend to export wastes to poor and undeveloped countries. On the other hand, undeveloped countries do not have enough capability to recycle these wastes which are generally hazardous and detrimental for human life and environment. After all, international actors struggle with this problem to protect environment by taking measures. The Basel convention is the most essential international agreement to prevent and regulate exportation of hazardous wastes. As a result, this study tries to explain the situation about waste exportation and to examine the international regulations for preventing waste exportation to the third World countries.
Magnetic Signatures of the 15 January 2022 Hunga Tonga–Hunga Ha'apai Volcanic Eruption

On 15 January 2022, at around 04:00 UTC, the submarine volcano Hunga Tonga‐Hunga Ha'apai explosively erupted. We examine data from 10 Pacific Ocean geomagnetic observatories and process the data using both high pass filters and cross‐wavelet analyses to enable evaluating the time‐frequency characteristics of the magnetic signals across the Pacific region. At the Western Samoa observatory (API), magnetic signals of 3–8 min period, and visible in both vertical and horizontal fields, arrived at ∼04:44 UTC. The observatories at Chichijima Island (CBI) and Easter Island (IPM) both had local magnetic signatures concurrent with the eruption's water wave arrival and period ranges from, respectively, 13–93 and 5–100+ min. At CBI and IPM, the magnetic signal may be due to both the eruption's tsunami water wave and atmospheric/ionospheric sources. Our results suggest that the magnetic signatures from the eruption are identifiable and may be further separated in future studies.
Effect of calcium supplement and physical exercises on selected parameters of postmenopausal osteoporosis in women

The aim of this study to identify the effect of the calcium supplement & physical exercises selected parameters in postmenopausal women. Material and Methods: The study used a descriptive evaluative approach with a pre-experimental control before-after research design, in which investigators assessed the effects of calcium supplementation and physical exercise on selected parameters in postmenopausal women in the outpatient departments of selected Mumbai hospitals. The research comprised 30 postmenopausal women from Mumbai's orthopaedic outpatient clinics. A basic random sampling method was employed to select the sample. ECOS 16 Questionnaire and Mini Osteoporosis Scale were used to obtain data. Describing and inferential statistics were used to analyses the data. Result: According to the findings of this research, Posttest mean blood calcium level 8.64 with SD of ±0.302 was higher than the Pretest mean blood calcium level 8.22 with SD of ± 0.370. In the t-test study the gap in Pretest and Posttest average blood calcium level was found to be considerable at the level of 0.05 (t=3.45; p<0.00001). This means that calcium supplements and exercise have a positive influence on postmenopausal women's calcium levels.
Selection methods of main circuit parameters for modular multilevel converters

The modular multilevel converter (MMC) will be used in power systems more and more widely. The main circuit parameter design of the MMC impacts the initial investment and the operating performance of the system. In this study the parameter design problem of several important elements in the main circuit of the MMC, such as the link transformer, the arm reactor, the sub-module (SM) capacitor and the SM power electronic devices are analysed. Based on the fundamental equivalent circuit of the MMC, the design method for the rated valve side no-load voltage of the link transformer is proposed; and the variation range of the rated valve side no-load voltage is determined as (1.00–1.05)/2 times of the DC side voltage. By introducing the concept of the equivalent capacity discharging time constant H, the nearly constant relationship between the fluctuation ratio of the SM capacitor voltage and the H-value for different projects is discovered, which means the H-value is independent of particular projects. In this study, the corresponding parameters of several practical projects are analysed and the recommended H-value is given as 40 ms. The voltage and current stress of the SM power electronic devices is investigated for the four extreme operating conditions by the analytical formulae of the MMC; and it is discovered that the current stress of the SM power electronic devices changes greatly with the operating condition. By introducing the concepts of the phase unit series resonance frequency and the circulating current resonance frequency, the principle for designing the parameter of the arm inductor is established. Through analysing the corresponding parameters of several real projects, the recommended value of the phase unit series resonance frequency is given as the rated frequency of the connected AC system.
IMPLEMENTATION OF GENETIC ALGORITHM FOR STUDENT PLACEMENT PROCESS OF COMMUNITY DEVELOPMENT PROGRAM IN UNIVERSITAS GADJAH MADA

Community Development Program (CDP) is a required subject in Universitas Gadjah Mada for undergraduate students to earn a bachelorâ€™s degree. One of the big problem in CDP implementation is student placement process into available thematic units. Each unit as much as possible filled by students which have balanced composition based on specified criteria. Balances in gender ratio and clusters composition are needed to have an objective assigned team students in a unit. In this paper, a genetic algorithm is proposed to solve this placement problem. The results of this paper is a simulation in CDP student placement process which using genetic algorithm to produce recommendation units which have good composition.
Helicobacter spp. in the Stomach of Cats: Successful Colonization and Absence of Relevant Histopathological Alterations Reveals High Adaptation to the Host Gastric Niche

In addition to Helicobacter pylori, many non-Helicobacter pylori Helicobacters (NHPH) are able to cause gastric disease in humans. Cats are a natural reservoir for many of these species. Accordingly, living in close and intimate contact with animals has been identified as a risk factor, and an important zoonotic significance has therefore been attributed to NHPH. To determine the prevalence and associated gastric histopathological changes of Helicobacter species, the gastric mucosa of 71 cats were evaluated. Only four presented normal histopathological mucosa with the absence of spiral-shaped organisms. Normal gastric mucosa and the presence of spiral-shaped bacteria were observed in 13 cats. The remaining animals presented histopathological changes representative of gastritis. Helicobacter species were detected in 53 cats (74.6%) by at least one detection method. None of the animals were positive for H. pylori or for H. ailurogastricus. Helicobacter heilmannii organisms were identified in 20 animals, predominantly in the body gastric region. Helicobacter salomonis was the second most prevalent species (57.1%), although it was mainly found in association with other NHPH. Helicobacter felis and H. bizzozeronii were less frequently detected. The great majority of the Helicobacter spp. PCR-positive animals presented normal features regarding fibrosis/mucosal atrophy, neutrophils, eosinophils, or other inflammatory cells and lymphofollicular hyperplasia. Given the controversy and the strong evidence of absence of significant histopathological alterations associated with the presence of Helicobacter spp. in cats, it is possible to hypothesize that these bacteria may be able to adapt to the feline gastric microenvironment or even to comprise part of the gastric microbiome of this animal species. Thus, prudency must be taken when prescribing an antibiotic therapy based solely on the presence of these bacteria in the feline stomach.
The Impact of Chronic Kidney Disease on Nutritional Status and Its Possible Relation with Oral Diseases

Several studies have demonstrated a strong relation between periodontal diseases and chronic kidney disease (CKD). The main mechanisms at the base of this link are malnutrition, vitamin dysregulation, especially of B-group vitamins and of C and D vitamins, oxidative stress, metabolic acidosis and low-grade inflammation. In particular, in hemodialysis (HD) adult patients, an impairment of nutritional status has been observed, induced not only by the HD procedures themselves, but also due to numerous CKD-related comorbidities. The alteration of nutritional assessment induces systemic manifestations that have repercussions on oral health, like oral microbiota dysbiosis, slow healing of wounds related to hypovitaminosis C, and an alteration of the supporting bone structures of the oral cavity related to metabolic acidosis and vitamin D deficiency. Low-grade inflammation has been observed to characterize periodontal diseases locally and, in a systemic manner, CKD contributes to the amplification of the pathological process, bidirectionally. Therefore, CKD and oral disease patients should be managed by a multidisciplinary professional team that can evaluate the possible co-presence of these two pathological conditions, that negatively influence each other, and set up therapeutic strategies to treat them. Once these patients have been identified, they should be included in a follow-up program, characterized by periodic checks in order to manage these pathological conditions.
Modulation of Dopamine Receptors on Osteoblasts as a Possible Therapeutic Strategy for Inducing Bone Formation in Arthritis

Rheumatoid arthritis (RA) is associated with systemic osteoporosis, which leads to severe disability and low quality of life. Current therapies target osteoclasts to reduce bone degradation, but more treatment options would be required to promote bone protection by acting directly on osteoblasts (OB). Recently, the local production of dopamine in inflamed joints of RA has been observed. Thus, in this project, we aimed to determine the implication of the neurotransmitter dopamine in the bone formation process in RA. Dopamine receptors (DR) in the human bone tissue of RA or osteoarthritis (OA) patients were examined by immunohistochemistry. DR in isolated human osteoblasts (OB) was analyzed by flow cytometry, and dopamine content was evaluated by ELISA. Osteoclasts (OC) were differentiated from the PBMCs of healthy controls (HC) and RA patients. Isolated cells were treated with specific dopamine agonists. The effect of dopamine on mineralization was evaluated by Alizarin red staining. Cytokine release in supernatants was measured by ELISA. Osteoclastogenesis was evaluated with TRAP staining. OC markers were analyzed via real-time PCR and bone resorption via staining of resorption pits with toluidine blue. All DR were observed in bone tissue, especially in the bone remodeling area. Isolated OB maintained DR expression, which allowed their study in vitro. Isolated OB expressed tyrosine hydroxylase, the rate-limiting enzyme for dopamine production, and contained dopamine. The activation of D2-like DR significantly increased bone mineralization in RA osteoblasts and increased osteoclastogenesis but did not alter the expression of OC markers nor bone resorption. DR were found in the bone remodeling area of human bone tissue and dopamine can be produced by osteoblasts themselves, thus suggesting a local autocrine/paracrine pathway of dopamine in the bone. D2-like DRs are responsible for bone mineralization in osteoblasts from RA patients without an increase in bone resorption, thus suggesting the D2-like DR pathway as a possible future therapeutic target to counteract bone resorption in arthritis.
A comparative evaluation of manufacturing flexibility adoption in SMEs and large firms in India

Purpose – The purpose of this paper is to analyse and compare the status of manufacturing flexibility adoption, its barriers and adoption practices in small and medium-sized enterprises (SMEs) and large firms in India. Design/methodology/approach – Using mixed methods sequential explanatory design, this study employs survey responses from 121 firms, followed by 16 semi-structured interviews to investigate and explain the status of manufacturing flexibility adoption, barriers to adoption and practices adopted to achieve flexibility in SMEs and large firms in India. Findings – The study suggests that awareness of manufacturing flexibility concept in SMEs is considerably low and application of manufacturing flexibility is still at embryonic stage. It was found that both SMEs and large firms employ manufacturing flexibility, but they differ with respect to their emphasis on adoption practices used to achieve flexibility. SMEs emphasize entrepreneurial orientation and flexible human resource practices to achie.