Miracle-dz/UniFAR-FTUs huggingface dataset:
Cross-Database Generalization of Deep Learning Models for Arrhythmia Classification

Arrhythmias are a wide-spread group of heart abnormalities. In the area of computational methods for ECG analysis, much research has been done on automated arrhythmia detection. In order to be able to develop such methods, databases containing various arrhythmia examples are necessary. The most popular such database is the MIT-BIH Arrhythmia database. Various deep learning architectures have shown superior arrhythmia classification performance on the MIT-BIH Arrhythmia database. However, the applicability of deep learning models for arrhythmia classification beyond their study-specific database has not been explored so far. In this paper, we test the cross-database generalization capabilities of a convolutional neural network, shown to successfully detect arrhythmias on MIT-BIH Arrhythmia, on three other public databases that contain the same arrhythmia groups, namely INCART, MIT-BIH Supraventricular Arrhythmia, and European ST-T. Additionally, our focus is on realistic evaluation schemes, namely inter-patient, to evaluate how well-established models are able to classify arrhythmias on a much larger number of distinct people not present in the training of the neural network. The results have shown that the cross-database generalization performance decreases if the conditions under which the measurements have been performed (lead position) in the other databases are not the same as in the MIT-BIH Arrhythmia database.
Kinematics and Force Analysis of Lifting Mechanism of Detachable Container Garbage Truck

The kinematics and force analysis of the lifting mechanism of the detachable container garbage truck is performed in this article. First of all, the structural features and working mechanism of detachable container garbage truck are introduced. Then, for each working condition of the DCG truck, kinematic models are established, and the force analysis of the lifting mechanism is performed. Finally, the movement of a 20 ton DCG truck is calculated and analyzed as an example. This study provides a theoretical basis for the optimized design of DCGgarbage truck.
Proposal of Study on Performance Analysis of OSPFV3 and EIGRP Applications in IPV6

The internet protocols are increasingly imposed in recent times, there is a need to propose a study on the performance analysis on OSPFV3 and EIGRP in IPV6 application. IP is currently involved in sensitive areas of internet protocols, remote sensing, telepresence, computer networks and so on. The IP exists in two versions (IPv4 and IPv6), the difference between these two protocols is distinguished in terms of features, operation, and performance. In this study, measuring and evaluation on the performance of the two IPv4 and IPv6 protocols in the networks of communicating companies are proposed for further studies based on the literature gaps identified. The study should be performed by varying the routing protocols RIP, RIPnG, OSPF, OSPFv3, IS-IS and ISIS v6. Further studies should conduct simulation on performance analysis of OSPFV3 and EIGRP in IPV6 applications. The gaps identified after reviewing a number of literature on OSPFV3 and EIGRP with IPV6 network needs to be done since it sought to bridge gaps in literature.
Systematic Review of Cost-Effectiveness of Injury Prevention Interventions in Soccer—Evidence Why Health Agencies Should Address It

Soccer injuries are a recognized problem worldwide. Several injury prevention programs have been confirmed to reduce the number of injuries in female and male players. Unfortunately, there is a lack of data about their cost, burden, and benefit for the health care system. In this paper we aim to systematically review the literature and critically evaluate the economic quality of injury prevention interventions implemented across different populations of soccer players. Web of Science, Medline, SPORTDiscus, Ovid, and other databases were searched from January 2011 through July 2021. Research articles were only selected for analysis if they focused on the cost-effectiveness of injury prevention, were experimental papers written in English, and were published following the peer-review process. Three cluster RCT and one retrospective study met the criteria. Cost data on incremental cost-effectiveness ratios (ICERs) were extracted. The included studies had a good/average quality of economic evaluation. Based on ICERs, injury prevention interventions were cost-effective in three out of the three comparisons. One study did not report the ICER value. However, since economic analyses were reported with varying methodological approaches and results, more data are required to recognize the cost-effectiveness of soccer-specific injury prevention interventions and their benefit for the health care system.
Therapeutic Effects of Inhibitor of ompA Expression against Carbapenem-Resistant Acinetobacter baumannii Strains

The widespread of carbapenem-resistant Acinetobacter baumannii (CRAB) is of great concern in clinical settings worldwide. It is urgent to develop new therapeutic agents against this pathogen. This study aimed to evaluate the therapeutic potentials of compound 62520, which has been previously identified as an inhibitor of the ompA promoter activity of A. baumannii, against CRAB isolates, both in vitro and in vivo. Compound 62520 was found to inhibit the ompA expression and biofilm formation in A. baumannii ATCC 17978 at sub-inhibitory concentrations in a dose-dependent manner. These inhibitory properties were also observed in clinical CRAB isolates belonging to sequence type (ST) 191. Additionally, compound 62520 exhibited a bacteriostatic activity against clinical clonal complex (CC) 208 CRAB isolates, including ST191, and ESKAPE pathogens. This bacteriostatic activity was not different between STs of CRAB isolates. Bacterial clearance was observed in mice infected with bioimaging A. baumannii strain 24 h after treatment with compound 62520. Compound 62520 was shown to significantly increase the survival rates of both immunocompetent and neutropenic mice infected with A. baumannii ATCC 17978. This compound also increased the survival rates of mice infected with clinical CRAB isolate. These results suggest that compound 62520 is a promising scaffold to develop a novel therapeutic agent against CRAB infections.
Intrauterine L-NAME Exposure Weakens the Development of Sympathetic Innervation and Induces the Remodeling of Arterial Vessels in Two-Week-Old Rats

Nitric oxide (NO) has been shown to stimulate differentiation and increase the survival of ganglionic sympathetic neurons. The proportion of neuronal NOS-immunoreactive sympathetic preganglionic neurons is particularly high in newborn rats and decreases with maturation. However, the role of NO in the development of vascular sympathetic innervation has never been studied before. We tested the hypothesis that intrauterine NO deficiency weakened the development of vascular sympathetic innervation and thereby changed the contractility of peripheral arteries and blood pressure level in two-week-old offspring. Pregnant rats consumed NOS inhibitor L-NAME (250 mg/L in drinking water) from gestational day 10 until delivery. Pups in the L-NAME group had a reduced body weight and blood level of NO metabolites at 1–2 postnatal days. Saphenous arteries from two-week-old L-NAME offspring demonstrated a lower density of sympathetic innervation, a smaller inner diameter, reduced maximal active force and decreased α-actin/β-actin mRNA expression ratio compared to the controls. Importantly, pups in the L-NAME group exhibited decreased blood pressure levels before, but not after, ganglionic blockade with chlorisondamine. In conclusion, intrauterine L-NAME exposure is followed by the impaired development of the sympathetic nervous system in early postnatal life, which is accompanied by the structural and functional remodeling of arterial blood vessels.
Ethyl Acetate Fraction from Leandra dasytricha (A. Gray) Cong. Leaves Promotes Vasodilatation and Reduces Blood Pressure in Normotensive and Hypertensive Rats

Leandra dasytricha (A. Gray) Cong. is widely distributed in the south of Brazil and is commonly used for cardiovascular and kidney ailments. For this study, we used male Wistar normotensive rats (NTRs) and spontaneously hypertensive rats (SHRs) to verify the effects of the ethyl acetate fraction (EAF) obtained from L. dasytricha leaves on isolated aorta relaxation and in the arterial blood pressure. The EAF was analyzed by LC-DAD-MS, and several components were annotated, including hydrolysable tannins, triterpenes, and O- and C-glycosylated dihydrochalcones, such as the most intense ion peak relative to C-hexosyl phloretin (nothofagin; compound number 13). The EAF caused a concentration and endothelium-dependent relaxation of the aorta in both NTRs and SHRs. This effect was abolished in the endothelium-denuded aorta. L-NAME, a nonselective nitric oxide synthase inhibitor, and ODQ, a soluble guanylate cyclase inhibitor, entirely blocked the EAF-induced relaxation. The presence of a muscarinic receptor antagonist or a cyclooxygenase inhibitor did not alter the EAF's effectiveness in relaxing the aorta. The preincubation with tetraethylammonium, a Ca2+-activated K+ channel blocker, and with 4-aminopyridine, a voltage-dependent K+ channel blocker, significantly interfered with the EAF's relaxation. However, the incubation with glibenclamide, an ATP-sensitive K+ channel blocker, and barium chloride, an inward-rectifier K+ channel blocker, did not interfere with the EAF-induced relaxation. The EAF treatment also caused a dose-dependent decrease in the mean arterial pressure, systolic arterial pressure, and diastolic arterial pressure of both NTRs and SHRs, without significantly interfering with heart rate values. In conclusion, this study demonstrated the EAF-induced vasorelaxant and hypotensive actions, primarily dependent on the endothelium function and mainly with the participation of the nitric oxide and Ca2+-activated and voltage-dependent K+ channels.
Employability or Learning? Groupwork in Higher Education.

An evaluation of the use of learning sets, supported by an electronic mailing list, on a level 2 research module on a Business Information Systems undergraduate degree, raises issues about the place of group work in higher education. Two models are discussed: a team‐based one, aimed largely at preparing students for employment and a group‐based one, aimed primarily at supporting the learning process. Confusion between the two is seen to parallel a blurring in workplace practice and to result in a lack of clarity on the part of both students and staff. The wider use of groups for learning is commended, but clarity on the role and purpose of group work is urged.
Taking DevOps mainstream: a critical review and conceptual framework

ABSTRACT Agile development and operations (DevOps) is a model for delivering software as a service that comprises a set of practices and tools combining the responsibilities for both developing and operating the software into a single team. DevOps has been shown to offer advantages over traditional, waterfall-based software development methods. Agile software development practices have radically changed how developers realize software, breaking traditional structures. DevOps enables the team to continuously deliver software. The scope of DevOps is different, as it focuses on the relation between the development and operations teams. Both the academic literature and business press opine on DevOps implementation challenges and failures. The literature on DevOps is abundant but fails to convey with clarity what DevOps is. The lack of a homogeneous and clear conceptualization of DevOps is considered a major obstacle to the diffusion of this methodology. We perform a systematic literature review to identify, review, and synthesise all the relevant studies published in the field of information systems and software engineering between 2012 and 2020. As a result of our review, we derive a conceptual model providing a logical categorisation and a clear definition of the conceptual elements of DevOps.
A global electromagnetic modeling of an active microstrip structure: Research Articles

This article presents a new technique that uses the auxiliary sources for investigation of structures including nonlinear components. The proposed technique is implemented in the iterative method to model two transistors (MESFET and INGFET) and an MMIC amplifier. The numerical results are compared with published data and a good agreement is observed. © 2007 Wiley Periodicals, Inc. Int J RF and Microwave CAE, 2007.
A Moving Ship Detection and Tracking Method Based on Optical Remote Sensing Images from the Geostationary Satellite

Geostationary optical remote sensing satellites, such as the GF-4, have a high temporal resolution and wide coverage, which enables the continuous tracking and observation of ship targets over a large range. However, the ship targets in the images are usually small and dim and the images are easily affected by clouds, islands and other factors, which make it difficult to detect the ship targets. This paper proposes a new method for detecting ships moving on the sea surface using GF-4 satellite images. First, the adaptive nonlinear gray stretch (ANGS) method was used to enhance the image and highlight small and dim ship targets. Second, a multi-scale dual-neighbor difference contrast measure (MDDCM) method was designed to enable detection of the position of the candidate ship target. The shape characteristics of each candidate area were analyzed to remove false ship targets. Finally, the joint probability data association (JPDA) method was used for multi-frame data association and tracking. Our results suggest that the proposed method can effectively detect and track moving ship targets in GF-4 satellite optical remote sensing images, with better detection performance than other classical methods.
Development of a Storage Retrieval Machine for High Racks Using a Wire Robot

Intralogistics systems are a rapidly growing market. Today, high racks and automated storage retrieval machines are widely used to store and handle industrial goods. Conventional storage retrieval machines show a major drawback: While the containers or goods to be moved are often very lightweight, the storage retrieval machine itself may weight up to two tons which limits the energy efficiency and the motion capabilities. This limitation is a problem since the reduction of cycle times is crucial in logistics applications. Therefore, faster motions are desired. At the same time, a main focus in intralogistics development is on energy-saving solutions as part of the ongoing climate change debate. Together with the rising energy costs, this paves the way for radical new concepts which go beyond the lightweight construction of conventional storage retrieval machines. Recently, a huge research project started to realize an alternative approach for a storage retrieval machine system. This approach uses a parallel wire robot system to move the goods to be stored to the desired position. The system is extremely lightweight and therefore, fast motions are possible while the required energy is comparably low. Therefore, cycle times for the transport of the goods can be drastically reduced which is crucial in this application. The paper presented here describes both design concepts which were already presented, as well as optimized geometries which are superior in terms of workspace coverage and stiffness. First simulation results are shown and discussed with a focus on the potential of the system for precise loading and unloading of containers. Besides that, the overall mechatronic system design is introduced.Copyright © 2012 by ASME
Impact of Various Essential Oils and Plant Extracts on the Characterization of the Composite Seaweed Hydrocolloid and Gac Pulp (Momordica cochinchinensis) Edible Film

Edible films and coatings have currently received increasing interest because of their potential in food applications. This study examined the effect of incorporated essential oils and natural plant extracts on the characteristics of the composite seaweed hydrocolloid and gac pulp films. Films were prepared by a casting technique, followed by measurement of physical, optical, barrier, mechanical, and structural properties. The results showed that adding plant oils and extracts significantly affected the physical, optical, mechanical, and structural properties of the composite films. Incorporation of the essential oils resulted in a reduction in moisture content and opacity while increasing values for Hue angle and elongation at break of the composite films. Besides, incorporation of the plant extracts showed increases in thickness, opacity, ΔE, Chroma, and elongation at the break, while there is a decrease in the Hue angle values of the composite films. In conclusion, incorporating plant essential oils and extracts into composite seaweed hydrocolloid and gac pulp films can enhance film properties, which can potentially be applied in food products.
Nutrition, Physical Activity, and Other Lifestyle Factors in the Prevention of Cognitive Decline and Dementia

Multiple factors combined are currently recognized as contributors to cognitive decline. The main independent risk factor for cognitive impairment and dementia is advanced age followed by other determinants such as genetic, socioeconomic, and environmental factors, including nutrition and physical activity. In the next decades, a rise in dementia cases is expected due largely to the aging of the world population. There are no hitherto effective pharmaceutical therapies to treat age-associated cognitive impairment and dementia, which underscores the crucial role of prevention. A relationship among diet, physical activity, and other lifestyle factors with cognitive function has been intensively studied with mounting evidence supporting the role of these determinants in the development of cognitive decline and dementia, which is a chief cause of disability globally. Several dietary patterns, foods, and nutrients have been investigated in this regard, with some encouraging and other disappointing results. This review presents the current evidence for the effects of dietary patterns, dietary components, some supplements, physical activity, sleep patterns, and social engagement on the prevention or delay of the onset of age-related cognitive decline and dementia.
Image colorization using Scaled-YOLOv4 detector

: Image Colorization is the problem of defining colors for grayscale images. Recently many research works have been conducted to propose fully-automatic colorization methods. However, many of these papers failed in colorizing images with multiple objects accurately. This might be because of dealing with the whole multi-object image as a single input. Following the efforts made in the last few years, this paper aims at studying the effect of preceding the image colorization with an object detection phase, such that the colorization will be made for each object individually as well as the full image. After the colorization of each object and the full image, they are fused together to reach a more
A New Microstrip Radiator For Medical Applications

Ring-type microstrip antennas appear to offer important advantages in medical therapy when used for local tissue heating. In designing these radiators, the properties of a microstrip covered with layers of lossy dielectric representing various tissue layers have to be taken into account. This paper provides basic information on design of ring-type radiators for tissue heating and the experimental results for a unit designed to operate in the TM modes at 2.45 GHz. The radiator is well matched when spaced 1.3-3 mm from muscle tissue or muscle tissue covered by a thin layer of fat tissue. A limited volume of muscle tissue is heated at a greater rate than the fat layer as shown by a thermographic technique.
The effect of dental caries and restorative biomaterials on IL-1 β and TNF-α levels in the gingival crevicular fluid

Background/Aim. In the spirit of personalized medicine, determining caries biomarkers in the saliva and gingival crevicular fluid (GCF) attracts great attention in the current dental re-search. The concentration of GCF cytokines is illustrative in depicting the processes in tooth structures. Their relevance must be inspected with aspects of tooth position and caries lesion level. Different impacts of dental restoration materials on GCF IL-1? and TNF-? could be used as a parameter for estimating local inflammation. This paper aimed to estimate the concentrations of the proinflammatory cytokines (IL-1? and TNF-? ) in the GCF and to correlate them with caries extension, tooth position, and different restorative biomaterials. Methods. GCF samples were collected from 90 periodontally healthy patients demonstrating at least one tooth with proximal caries and one intact tooth, at the baseline, 7 and 30-days post-treatment. The biomarkers? profile was investigated in relation to different levels of caries extension (superficial, pulpitis, gangrenous, root affection), defect size, and restorative biomaterial. Results. Before therapy, caries level was significantly associated with GCF IL-1? concentration, demonstrating the lowest level in gangrenous (C4) and superficial caries (C2). Thirty days after therapy, root affection (C5) was characterized by the highest IL-1? concentration. Different dental fillings showed various GCF cytokine changes. CPC induced a significant IL-1? increase in more than 70% of treated patients. Caries lesion size was insignificantly associated with GCF levels of these proinflammatory cytokines, where larger defects were followed by an average cytokine increase. Considering the tooth position be-fore therapy, IL-1? had the highest level in GCF samples from caries-affected canines and second molars, while TNF-? showed the highest levels from canines GCF. Dental restoration induced cytokine increase in canines (IL-1? and TNF-? ), 1st and 2nd molars GCF (IL-1? ). Conclusion. Inflammation intensity of tooth structures was directly reflected in IL-1? and TNF-? concentrations. Dental restoration significantly affects IL-1? and TNF-? levels, depending on the used dental filling-type material. The profile of these cytokines varied in GCF samples of the tooth with different anatomical positions, where canines and molars demonstrated the highest level. An increase of these proinflammatory cytokines in the absence of any symptomatic manifestation of the inflammatory response can be considered as a possible tooth reparation parameter.
Political competitive advantage in the usa: an rbv approach

ABSTRACT In the last decade, attention was given to the distinctive role of organizational resources and capabilities in the achievement of higher performance via the resource-based view tool (RBV). However, RBV research has not given attention to the role of specific resources and capabilities in gaining a political competitive advantage. Drawing from the literature on marketing and strategic management, this study develops a model of drivers and outcomes of political marketing strategies in the U.S.A. Data were collected from 128 U.S. elected politicians. Using factor analysis, the current study identifies two new factors regressed with the 4Ps Marketing Strategy: (a) ”Personality and Capability to Stand Behind Ideas”, and (b) ‘Financial Resources to Fund Opposition Research’. In turn, the study points out that the adoption of the 4Ps Political Marketing Strategy significantly increases the potential to gain a Political Competitive Advantage. Several implications are drawn from the study findings and further directions for future research are provided.