Miracle-dz/UniFAR-FTUs huggingface dataset:
Evaluation of Aging Effects on Skin Wrinkle by Finite Element Method

The reason why the wrinkle suddenly becomes prominent at a middle age is addressed from biomechanical standpoint. The multistage buckling theory we have derived concludes that the sudden enlargement of wrinkle comes from a switch of the specific buckling mode from the horny buckling to the epidermal buckling. In this study, the validity of this conclusion was reexamined by the finite element buckling analysis of the human facial skin with a linear aging model. Comparison of results between the beam model and the finite element model unraveled the mechanism of the buckling mode switch. By simulating the three cases: epidermal aging, dermal aging, and full aging, we found that the mode switch mainly comes from the epidermal aging, that is, the stiffening and thinning of the epidermis. The dermal aging was not a trigger of the mode switch in the linear buckling of linear aging skin model.
Genomic profiles and their associations with TMB, PD-L1 expression, and immune cell infiltration landscapes in synchronous multiple primary lung cancers

Background Diagnosing and treating patients with multiple primary lung cancers (MPLCs) bring challenges to the clinic, and the preliminary evidence has revealed unsatisfying outcomes after targeted therapy and immunotherapy. Therefore, we surveyed genomic profiles of MPLCs and their possible associations with tumor mutation burden (TMB), programmed death-ligand 1 (PD-L1), and the immune cell infiltration landscape. Materials and methods A total of 112 patients with MPLCs with surgically resected 294 tumors were eligible, and 255 tumors were sequenced using a 1021-gene panel. Immunohistochemistry staining was performed to evaluate the levels of PD-L1 and the density of CD3+/CD8+ tumor-infiltrating lymphocytes (TILs), and CD68+/CD163+ tumor-associated macrophages (TAMs) at the central tumor and invasive margin, and immunotypes were generated based on those variables. Results MPLCs often occur simultaneously in non-smoker women younger than 60 years and manifest as ground-glass opacities, adenocarcinoma, and stage I lung lesions. The most frequently mutated genes in the 255 tumors were EGFR (56%), ERBB2 (12%), TP53 (12%), BRAF (11%), RBM10 (11%), and KRAS (9%). We found 87 (77.7%) patients with diverse genomic profiles, and 61 (54.5%) who shared at least one putative driver gene between different tumors presented more aggressive tumors. The median TMB was 1.92 mutations/Mb, and high-TMB (≥3) lesions often harbored EGFRL858R/KRASG12C/RBM10/TP53/LRP1B mutations or wild-type ERBB2. Only 8.1% of patients and 3.9% of lesions were positive for PD-L1 on tumor cells, and this positivity was more frequent in LRP1B/TP53-mutant tumors. EGFRL858R/RBM10/TP53 mutations were positively associated with specific immune cells and an inflamed immunotype, but ERBB2 mutations were negatively correlated. TMB, CD3+TILs, and CD68+/CD163+ TAMs presented with significant heterogeneity among paired tumors (all kappa <0.2), but PD-L1 and CD8 +TILs were more uniformly present in tumor pairs. Conclusion MPLCs are driven by different molecular events and often exhibit low TMB, low PD-L1, and a heterogeneous immune infiltration landscape. Specific genomic profiles are associated with TMB and the tumor immune microenvironmental landscape in MPLCs. Our findings can help to guide MPLCs diagnoses and to identify patient populations that may benefit from immunotherapy and targeted therapy.
On the performance advantage of PD/SOI CMOS with floating bodies

The performance advantage of floating-body (FB) partially depleted (PD) SOI CMOS technology is analyzed via device/circuit simulations, with emphasis on providing insight into the physical mechanisms underlying the advantage. Comparisons of predicted propagation delay of contemporary and scaled FB PD/SOI CMOS, including hysteresis, with those of the bulk-Si and body-tied-to-source/SOI counterparts, all with controlled off-state current, are made, and the impact of junction capacitance, the kink effect, and capacitive-coupling effects are quantified. Scaling the technologies is shown to diminish the performance advantage of FB PD/SOI CMOS, but this tendency can be mitigated by typically elevated operating temperatures, stacked-transistor logic, and device-design optimization.
Associations between Visual Acuity and Cognitive Decline in Older Adulthood: A 9-Year Longitudinal Study

Abstract Objective: Emerging evidence suggests low vision may be a modifiable risk factor for cognitive decline. We examined effects of baseline visual acuity (VA) on level of, and change in, cognitive test performance over 9 years. Method: A population-based sample of 1,621 participants (average age 77 years) completed a comprehensive neuropsychological evaluation and VA testing at baseline and reassessed at nine subsequent annual visits. Linear regression modeled the association between baseline VA and concurrent cognitive test performance. Joint modeling of a longitudinal sub-model and a survival sub-model to adjust for attrition were used to examine associations between baseline VA and repeated cognitive test performance over time. Results: Better baseline VA was associated cross-sectionally with younger age, male sex, greater than high school education, and higher baseline neuropsychological test scores on both vision-dependent (B coefficient range −0.163 to −0.375, p = .006 to <.001) and vision-independent tests (−0.187 to −0.215, p = .003 to .002). In longitudinal modeling, better baseline VA was associated with slower decline in vision-dependent tests (B coefficient range −0.092 to 0.111, p = .005 to <.001) and vision-independent tests (−0.107 to 0.067, p = .007 to <.001). Conclusions: Higher VA is associated with higher concurrent cognitive abilities and slower rates of decline over 9 years in both vision-dependent and vision-independent tests of memory, language, and executive functioning. Findings are consistent with emerging literature supporting vision impairment in aging as a potentially modifiable risk factor for cognitive decline. Clinicians should encourage patient utilization of vision assessment and correction with the added aim of protecting cognition.
Gestão de projetos internacionais: um estudo bibliométrico

The global economy, supported by technological progress, political changes and economic interdependency, has shaped a business environment that differs radically from the past. This new context has conducted organizations to develop and execute projects beyond national boundaries, both in terms of project scope and composition of project teams. However, international projects usually imply greater risks and uncertainty, making competence in the management of international projects a strategic element to organizations these days. The aim of this paper is to analyze the literature related to the management of international projects, trying to identify the main challenges and characteristics of this management activity. The methodological approach is based on systematic literature review, supported by bibliometric techniques and social network analysis. The database chosen for the selection of sample articles was the ISI Web of Knowledge (web of Science). Analyses suggest that a major portion of the literature related to the management of international projects has its theoretical foundations on investigations of cultural and behavioral differences between individuals. Results also suggest that one of the main challenges to the management of international projects resides on the effective integration of the project itself and its dispersed teams, a process that tends to be hampered by communicative, knowledge sharing, and decision making barriers inherent to this context.
Modeling the conducted EMI emission of an electric vehicle (EV) traction drive

This paper derives simple but insightful models to study the conducted EMI noise of an electric vehicle (EV) traction drive, where the equivalent noise sources are characterized, dominant distribution paths are found and the spectrum of the conducted noise on the DC bus is estimated accordingly. Experiment results are included to support the proposed theoretical models.
Thin film resonator technology

The thin film resonator technology has been under development for over forty years in one form or another. Although the basic approach is derived from the desire to reach higher frequencies than those readily achieved by thinning bulk crystals, there have always been competing technologies or fundamental material or processing problems that have impeded the development. Finally, a point was reached in the wireless market wherein competing technologies appeared unable to meet the demands of modern wireless applications and thin film approaches began to receive some emphasis. This paper will survey the thin film resonator technology. Every effort will be made to provide an objective analysis of the technology in relation to applications and competing technologies, and point out obstacles and promises, as known, for further technology advancement to high frequencies.
Méthode de mesure et de modélisation de canaux de propagation radiomobile

This work deals with both the narrow band and the large band characterization of the mobile channel in the specific context of macrodiversity. It is divided into experiments and more theoretical studies. All the results presented here were achieved at the France Telecom Research and Development (FTR&D) center. During the most critical phases of a mobile transmission, especially when the mobile lies on the border of a cell, it may be advantageous to connect it with one or several other base stations at the same time. This is what we call macrodiversity. This technique is inherent to new generation mobile systems. In CDMA for example, over 40% of the mobiles use it. The handover algorithm and its performances may depend on the low fading recorded on the different paths. They may also depend on the fast fading or on the impulse response profiles. This shows the paramount importance of a good channel knowledge and modelisation in situation of macrodiversity. It is with these goals in mind that this thesis was written. We first performed narrow band studies thanks to measurements and simulations. This helped us to build a complete model of the shadow fading, including both its autocorrelation and cross-correlation properties. Next, this model was implemented in system and capacity simulators, allowing the restoration of the shadowing phenomenon in a more realistic way. We completed our work with large band studies. To do so, we had to perfect the available FTR&D channel sounder and to imagine new measurement protocols. Eventually, we patented a large band sounding method in macrodiversity. We were also able do derive from this a method dedicated to channel identification in the more general context of numerical communications. At last, we tried to optimise the pseudo random sequences used in channel sounders and identifiers.
Series Representations for Uncertain Fractional IVPs in the Fuzzy Conformable Fractional Sense

Fuzzy differential equations provide a crucial tool for modeling numerous phenomena and uncertainties that potentially arise in various applications across physics, applied sciences and engineering. Reliable and effective analytical methods are necessary to obtain the required solutions, as it is very difficult to obtain accurate solutions for certain fuzzy differential equations. In this paper, certain fuzzy approximate solutions are constructed and analyzed by means of a residual power series (RPS) technique involving some class of fuzzy fractional differential equations. The considered methodology for finding the fuzzy solutions relies on converting the target equations into two fractional crisp systems in terms of ρ-cut representations. The residual power series therefore gives solutions for the converted systems by combining fractional residual functions and fractional Taylor expansions to obtain values of the coefficients of the fractional power series. To validate the efficiency and the applicability of our proposed approach we derive solutions of the fuzzy fractional initial value problem by testing two attractive applications. The compatibility of the behavior of the solutions is determined via some graphical and numerical analysis of the proposed results. Moreover, the comparative results point out that the proposed method is more accurate compared to the other existing methods. Finally, the results attained in this article emphasize that the residual power series technique is easy, efficient, and fast for predicting solutions of the uncertain models arising in real physical phenomena.
Dust-cloud density estimation using a single wavelength lidar

The passage of commercial and military aircraft through invisible fresh volcanic ash clouds has caused damage to many airplanes. On December 15, 1989 all four engines of a KLM Boeing 747 were temporarily extinguished in a flight over Alaska resulting in $DOL80 million for repair. Similar aircraft damage to control systems, FLIR/EO windows, wind screens, radomes, aircraft leading edges, and aircraft data systems were reported in Operation Desert Storm during combat flights through high-explosive and naturally occurring desert dusts. The Defense Nuclear Agency is currently developing a compact and rugged lidar under the Aircraft Sensors Program to detect and estimate the mass density of nuclear-explosion produced dust clouds, high-explosive produced dust clouds, and fresh volcanic dust clouds at horizontal distances of up to 40 km from an aircraft. Given this mass density information, the pilot has an option of avoiding or flying through the upcoming cloud.
Automatic Extraction of Indoor Spatial Information from Floor Plan Image: A Patch-Based Deep Learning Methodology Application on Large-Scale Complex Buildings

Automatic floor plan analysis has gained increased attention in recent research. However, numerous studies related to this area are mainly experiments conducted with a simplified floor plan dataset with low resolution and a small housing scale due to the suitability for a data-driven model. For practical use, it is necessary to focus more on large-scale complex buildings to utilize indoor structures, such as reconstructing multi-use buildings for indoor navigation. This study aimed to build a framework using CNN (Convolution Neural Networks) for analyzing a floor plan with various scales of complex buildings. By dividing a floor plan into a set of normalized patches, the framework enables the proposed CNN model to process varied scale or high-resolution inputs, which is a barrier for existing methods. The model detected building objects per patch and assembled them into one result by multiplying the corresponding translation matrix. Finally, the detected building objects were vectorized, considering their compatibility in 3D modeling. As a result, our framework exhibited similar performance in detection rate (87.77%) and recognition accuracy (85.53%) to that of existing studies, despite the complexity of the data used. Through our study, the practical aspects of automatic floor plan analysis can be expanded.
Analysis of the Modification Method for Cook-Torrance Model

A visible difference exists between the measured Bidirectional Reflectance Distribution Function (BRDF) and the modeled BRDF. The Cook-Torrance model is chosen to simulate the BRDF for its popularity and flexibility. Taking aluminum for example, this paper analyzes the difference between the experiment data and the simulation data. There is a great and remarkable difference in the situation of specular reflection by comparison in this paper. Consequently, trigonometric factor, numerator and denominator addition factors and scaling factor are brought in the Cook-Torrance model. Finally, a modified Cook-Torrance model is presented. The simulation data of the modified Cook-Torrance model show that it’s more suitable for the analysis of the aluminum BRDF than the classic Cook-Torrance model.
Development of a decision support system for sustainable and resilience evaluation of urban underground space physical infrastructure

The research described in this thesis proposes a new,novel evaluation ‘framework’ and accompanying operational ‘model’, the ‘SUURE’ (Sustainable Underground Use Resilience Evaluation) ‘framework’, which adopts a socio-ecological systems (SES) approach to evaluation, combining sustainability science and resilience theory, at the same time incorporating a range of interdisciplinary tools and methods to achieve this. It purposes at its core to aid in sustainability evaluation of urban underground space, by evaluating the process to the outcome of sustainable solutions i.e. the capacity to adapt to change in different steady states. In consequence, a fundamentally different approach to planning that utilises future socio-ecological scenarios (NSP, PR, MF and FW) is incorporated in the ‘framework’ as a means of evaluating through its operational ‘model’, the sensitivity of investment decisions made today in the name of sustainability i.e. will the proposed engineering sustainability solution continue to deliver its intended function into the future, whatever that may be. The SUURE operational ‘model’ was employed as a proof of concept to the case study area of Birmingham Eastside, evaluating the potential use of multi-utility tunnels (MUT) in Eastside as a means of engendering sustainable and resilient use of urban underground space, through sustainable utility placement, both now and into the future. The flush-fitting MUT was found to be having the highest overall baseline (present-day) performance resilience index ratio at mean of 0.739, the shallow MUT second at 0.656, and the deep MUT last at 0.212. With regard to the evaluation of continued MUT functional performance into the future (whatever that may be), all three MUT options, if implemented today in the name of sustainability, would continue to deliver and retain their core functional performance, the deep MUT showing the most significant increase across all evaluation clusters (social, economic, physical, bio-physical and location aspects).
Implementing ATVAM, the World's largest ITS Program, across Saudi Arabia

With 18 fatal road accidents per day and a population of 27million, Saudi Arabia experiences five times the road deaths of its European counterparts. Issues such as a migrant population of over 20% also present huge problems for traffic management and security. The ATVAM program (Automated Traffic Violations Administering and Monitoring) is tackling these issues with an unprecedented investment estimated at over $1.5Bn in ITS systems countrywide over a 6 year period. The program is integrating law enforcement, traffic management and security systems to improve traffic safety & mobility in the Kingdom. (6 pages)
The "Sofia Model": Creation out of chaos. Pathways to creative and knowledge-based regions

Disclaimer/Complaints regulations If you believe that digital publication of certain material infringes any of your rights or (privacy) interests, please let the Library know, stating your reasons. In case of a legitimate complaint, the Library will make the material inaccessible and/or remove it from the website. Please Ask the Library: http://uba.uva. nl/en/contact, or a letter to: Library of the University of Amsterdam, Secretariat, Singel 425, 1012 WP Amsterdam, The Netherlands. You will be contacted as soon as possible.
Defect control and Si/Ge core–shell heterojunction formation on silicon nanowire surfaces formed using the top-down method

Control of surface defects and impurity doping are important keys to realizing devices that use semiconductor nanowires (NWs). As a structure capable of suppressing impurity scattering, p-Si/i (intrinsic)-Ge core–shell NWs with radial heterojunctions inside the NWs were formed. When forming NWs using a top-down method, the positions of the NWs can be controlled, but their surface is damaged. When heat treatment for repairing surface damage is performed, the surface roughness of the NWs closely depends on the kind of atmospheric gas. Oxidation and chemical etching prior to shell formation removes the surface damaged layer on p-SiNWs and simultaneously achieves a reduction in the diameter of the NWs. Finally, hole gas accumulation, which is important for suppressing impurity scattering, can be observed in the i-Ge layers of p-Si/i-Ge core–shell NWs.
An Island Studies Course at a Liberal Arts Institution: Pedagogy from a Natural History Perspective

An intellectual treatment of islands and isolation lends itself to a foundation in a liberal arts education. The introductory undergraduate course on island studies can serve as a topical platform on which to develop critical thinking, research, analytical, and creative thinking skills for beginning college students. The paper analyzes the natural history perspective in island studies and its methods of inquiry as pedagogical strategies that enhance the development of academic curiosity. The success of this approach to early undergraduate education is documented in traditional assessment and the direction that student-driven inquiry followed throughout the course. A course in island studies is a natural fit into progressive curriculum design strategies that are currently under development at many colleges and universities.
Study on Performance Comparison of OLSR and AODV Routing Protocols

A Mobile Ad hoc network (MANET) is a network consisting of a set of wireless mobile nodes, in which nodes can communicate with each other without centralized control or established infrastructure. To obtain a better understanding of AODV (Ad hoc On-Demand Distance Vector Routing Protocol) and OLSR (Optimized Link State Routing Protocol) routing protocols, different performances are simulated and analyzed using OPNET modeler 14.5 with the various performance metrics, such as PDR (Packet Delivery Ratio), end-to-end delay and routing overhead. Only effect of mobility is analyzed in the paper. As a conclusion, in mobility case, routing overhead is not greatly affected by mobility speed in AODV and OLSR, and the PDR of OLSR is decreased as the node speed increased, while AODV is not changed. As to delay, AODV is always higher than OLSR in both static and mobility cases.
A practical method to improve phasor and power measurement accuracy of DFT algorithm

Centralized control, which can overcome the ill interactional effects among decentralized controllers, impels a real need for fast and reliable computational algorithms to improve the accuracy of phasor and power measurements. This paper deals with discrete Fourier transform (DFT)-based measurement techniques. Based on the practical frequency tracking method proposed by the same authors in another paper, this paper develops practical compensation method to improve the phasor and power measurement accuracy of the DFT algorithm. The method proposed by this paper takes full advantage of the DFT algorithm. It simply modifies the DFT results. With notable accuracy improvement, the calculation burden of the proposed method is little more than the DFT algorithm. The method can be used for on-line purposes. Though the analog signal studied in this paper is sinusoidal signal, the method proposed by this paper has good performance in the presence of harmonics. Some examples are given to demonstrate the feasibility, simpleness and robustness of the proposed method.