Miracle-dz/UniFAR-FTUs huggingface dataset:
Journal of Experimental Botany Advance Access published July 10, 2006 Journal of Experimental Botany, Page 1 of 13

Thirteen nodule-specific or nodule-enhanced genes encoding products homologous to cysteine cluster proteins or plant lipid transfer proteins are identified in Astragalus sinicus L. by suppressive subtractive hybridization Abstract Thirteen nodule-specific or nodule-enhanced genes have been revealed by suppressive subtractive hybrid-ization (SSH) with two mRNA populations of infected and uninfected control roots of Astragalus sinicus. Eleven of them encode small polypeptides showing homology to cysteine cluster proteins (CCPs) that contain a putative signal peptide and conserved cys-teine residues. Among these CCP-like genes, AsG257 codes for a homologue of the defensin 2 family and AsD255 contains a scorpion toxin-like domain at the C-terminus. Sequence analysis of a genomic AsD255 fragment which was isolated revealed that one intron separates the first exon encoding the signal peptide from the second exon encoding the cysteine cluster domain of this nodulin. Another two genes, AsE246 and AsIB259, encode two different products similar to lipid transfer proteins (LTPs). Virtual northern blot and reverse transcription–polymerase chain reaction (RT– PCR) analysis indicated that the other genes except AsIB259 and AsC2411 were expressed exclusively in inoculated roots and that their expression was 2–4 d later than that of the leghaemoglobin (Lb) gene during nodule development. Transcription of AsIB259 was also detected in uninfected control roots but with a significant decline in expression and a temporal expression similar to Lb. AsC2411 had a basal expression in control roots identified by RT–PCR. Sequence alignment showed that the putative proteins AsE246 and AsIB259 show lower homology with LTPs from legumes than with those from other plants.
The presence of jasmonate-inducible lectin genes in some but not all Nicotiana species explains a marked intragenus difference in plant responses to hormone treatment

Tobacco (Nicotiana tabacum L. cv Samsun NN) leaves accumulate a cytoplasmic/nuclear lectin, called Nictaba, in response to methyl jasmonate. To check whether, and if so to what extent, the specific induction of this lectin applies to related species, a collection of 19 Nicotiana species—covering 12 Nicotiana sections and eight Nicotiana tabacum cultivars—was screened for their capability to synthesize the jasmonate-inducible lectin. Protein analyses by agglutination assays and western blot confirmed that only nine out of the 19 species examined synthesize lectin after jasmonate treatment. Remarkably, all allotetraploid cultivars of the N. tabacum L. species tested express the lectin after jasmonate treatment. PCR analyses demonstrated that all responsive species possess one or more lectin genes, whereas no lectin gene(s) could be traced in the non-responding species. The number of introns present in the lectin genes varies between zero and two. Four tobacco species/cultivars contain both intronless Nictaba genes as well as lectin genes with introns. These findings provide the first firm evidence for a striking intragenus difference with respect to the activation of a well-defined jasmonate-inducible gene that can be correlated with the presence/absence of orthologous genes in the genomes of closely related species from a single plant genus. In addition, the differential response of closely related tobacco species illustrates that in the field of plant hormone research, care must be taken when extrapolating results obtained with a particular model system to other—even taxonomically closely related—species.
Nebulised dexmedetomidine for patient’s comfort and satisfaction during diagnostic upper gastrointestinal endoscopy: A double-blind randomised controlled study

Upper gastrointestinal endoscopy (UGE) is an uneasy and stressful event for most patients. [1] Various strategies and drugs have been used to provide patient comfort during UGE with variable effects and limitations. [2-5] Dexmedetomidine has been used in anaesthesia practice for sedation, given its beneficial effect in avoiding airway and respiratory compromise. [5,6] Nebulised dexmedetomidine has been studied in paediatric patients for sedation in daycare procedures. [7] It also alleviates the stress response to laryngoscopy and intubation. [5] Nevertheless, it has not been investigated in UGE procedures. We hypothesised that nebulised dexmedetomidine improves patients’ comfort and satisfaction during UGE.
Misalignment Compensation for Full Human-Exoskeleton Kinematic Compatibility: State of the Art and Evaluation

The use of exoskeletons by the elderly, disabled people, heavy labor workers, and soldiers can have great social and economic benefit. However, limitations in usability are impeding the widespread adoption of exoskeletal devices. Kinematic compatibility, comfort, volume, mass, simplicity, expandability, and the ability to transmit forces, relative angles between the exoskeleton and the human, and the donning and doffing procedure need to be considered. Over the last decades, a large number of exoskeletons have been developed, to assert kinematic compatibility and compensate for misalignment. To such a degree, that it has become difficult to keep an overview of the different strategies. Therefore, this review article presents an extensive overview of different misalignment compensation strategies existing in the literature. Further, these strategies are organized in nine categories, evaluated and discussed around the exoskeleton's application domain and its specific requirements and needs.
Loss of dlx5a/dlx6a Locus Alters Non-Canonical Wnt Signaling and Meckel’s Cartilage Morphology

The dlx genes encode transcription factors that establish a proximal–distal polarity within neural crest cells to bestow a regional identity during craniofacial development. The expression regions of dlx paralogs are overlapping yet distinct within the zebrafish pharyngeal arches and may also be involved in progressive morphologic changes and organization of chondrocytes of the face. However, how each dlx paralog of dlx1a, dlx2a, dlx5a and dlx6a affects craniofacial development is still largely unknown. We report here that the average lengths of the Meckel’s, palatoquadrate and ceratohyal cartilages in different dlx mutants were altered. Mutants for dlx5a−/− and dlx5i6−/−, where the entire dlx5a/dlx6a locus was deleted, have the shortest lengths for all three structures at 5 days post fertilization (dpf). This phenotype was also observed in 14 dpf larvae. Loss of dlx5i6 also resulted in increased proliferation of neural crest cells and expression of chondrogenic markers. Additionally, altered expression and function of non-canonical Wnt signaling were observed in these mutants suggesting a novel interaction between dlx5i6 locus and non-canonical Wnt pathway regulating ventral cartilage morphogenesis.
Assessing white matter microstructural changes in idiopathic normal pressure hydrocephalus using voxel-based R2* relaxometry analysis

Background R2* relaxometry and quantitative susceptibility mapping can be combined to distinguish between microstructural changes and iron deposition in white matter. Here, we aimed to explore microstructural changes in the white matter associated with clinical presentations such as cognitive impairment in patients with idiopathic normal-pressure hydrocephalus (iNPH) using R2* relaxometry analysis in combination with quantitative susceptibility mapping. Methods We evaluated 16 patients clinically diagnosed with possible or probable iNPH and 18 matched healthy controls (HC) who were chosen based on similarity in age and sex. R2* and quantitative susceptibility mapping were compared using voxel-wise and atlas-based one-way analysis of covariance (ANCOVA). Finally, partial correlation analyses were performed to assess the relationship between R2* and clinical presentations. Results R2* was lower in some white matter regions, including the bilateral superior longitudinal fascicle and sagittal stratum, in the iNPH group compared to the HC group. The voxel-based quantitative susceptibility mapping results did not differ between the groups. The atlas-based group comparisons yielded negative mean susceptibility values in almost all brain regions, indicating no clear paramagnetic iron deposition in the white matter of any subject. R2* and cognitive performance scores between the left superior longitudinal fasciculus (SLF) and right sagittal stratum (SS) were positively correlated. In addition to that, R2* and gait disturbance scores between left SS were negatively correlated. Conclusion Our analysis highlights the microstructural changes without iron deposition in the SLF and SS, and their association with cognitive impairment and gait disturbance in patients with iNPH.
Morphology and organ weight of dugongs (Dugong dugon) in Thai waters

Data were obtained from dugong specimens collected in Thai waters during 22 June 1979 to 31 October 2009. Length and weight of calves ranged from 0.97-1.31 and 14-50 kg (n = 14). The average length of mature male and female was 2.58 ± 0.18 m (SD) (n = 12) and 2.55 ± 0.17 m (n = 23). The average weight of mature male and female was 249.6 ± 40.6 kg (n = 7) and 251.2 ± 55.2 kg (n = 17). Meat was the main part of dugong followed by blubber, while bone and internal organs were of similar proportion (n = 44). Organ weight from maximum to minimum was; lung, liver, kidney and heart. Weights (kg) of lung: liver: kidney: heart in male were 2.99 ± 1.01: 2.52 ± 0.73: 0.88 ± 0.21: 0.53 ± 0.18 (n = 11) and those weights (kg) in female were 3.35 ± 0.94: 3.09 ± 1.00: 1.26 ± 0.50: 0.53±0.19 (n = 7). Brain was very small, only 0.1% of body weight. Food contents in the stomachs of male and female were 1.92 ± 0.99% and 2.8 ± 1.13% of their body weight (n = 45). The maximum length of intestine was 12.04 ± 2.1 times of the body length (n = 44).
Inhibitory effects of Buddleja scordioides (salvilla) leaves on digestive enzymes and carbohydrate absorption in vivo

The effects of Buddleja scordioides (BsLI) leaf infusions on digestive enzymes and carbohydrate absorption were evaluated. The BsLI yield was 21.64 %. In addition, a chemical characterization was carried out identifying hydroxybenzoic acids, hydroxycinnamic acids, flavonols, flavanones and flavones. In vitro studies were performed to determine the inhibitory action of BsLI on lipase, α-amylase, and α-glucosidase. Then, in rats, oral starch tolerance tests (OSTT) were carried out using BsLI at a dose of 9.5 mg/kg body weight. Results showed moderate inhibition of lipase and α-glucosidase, but greater inhibition of α-amylase compared to positive controls. During the OSTT trial, the group receiving BsLI showed a significant reduction in glucose levels compared to the negative control group. Bioactive compounds, such as naringenin, luteolin, quercetin, and coumaric acid, were identified after BsLI administration. Furthermore, the consumption of BsLI was safe and showed antioxidant activity like Trolox. In conclusion, BsLI may have an enhanced effect on glucose metabolism by inhibiting carbohydrate absorption. DOI: https://doi.org/10.54167/tch.v17i2. 1221
Recent Advances in the Treatment of Pulmonary Arterial Hypertension Associated with Connective Tissue Diseases

Pulmonary hypertension (PH) is a severe vascular complication of connective tissue diseases (CTD). Patients with CTD may develop PH belonging to diverse groups: (1) pulmonary arterial hypertension (PAH), (2) PH due to left heart disease, (3) secondary PH due to lung disease and/or hypoxia and (4) chronic thromboembolic pulmonary hypertension (CTEPH). PAH most often develops in systemic scleroderma (SSc), mostly in its limited variant. PAH-CTD is a progressive disease characterized by poor prognosis. Therefore, early diagnosis should be established. A specific treatment for PAH-CTD is currently available and recommended: prostacyclin derivative (treprostinil, epoprostenol, iloprost, selexipag), nitric oxide and natriuretic pathway: stimulators of soluble guanylate cyclase (sGC: riociguat) and phosphodiesterase-five inhibitors (PDE5i: sildenafil, tadalafil), endothelin receptor antagonists (ERA: bosentan, macitentan, ambrisentan). Moreover, novel drugs, e.g., sotatercept, have been intensively investigated in clinical trials. We aim to review the literature on recent advances in the treatment strategy and prognosis of patients with PAH-CTD. In this manuscript, we discuss the mechanism of action of PAH-specific drugs and new agents and the latest research conducted on PAH-CTD patients.
Disinformation narratives in Spain: reach, impact and spreading patterns

We present data from a survey conducted in Spain (N = 1003) in March 2022. We analysed fact-checker activity to obtain daily information regarding disinformation content encountered in the three weeks before the survey was launched. The research team analysed the material found to identify content that was related or that belonged to similar narratives. The goal was to identify the key disinformation narratives that were spreading before the survey, rather than just isolated content, to test the reach and impact of disinformation narratives, as well as spreading patterns, through survey research. Results point towards the fact that disinformation narratives were spread among a majority of respondents, with TV and social media being the main media responsible for spreading them. In addition, those that received the narratives before were more likely to believe them, indicating the disinformation narratives’ potential high impact.
The Behavioral Mechanisms of Voluntary Cooperation Across Culturally Diverse Societies: Evidence from the Us, the UK, Morocco, and Turkey

IZA DP No. 16415 AUGUST 2023 The Behavioral Mechanisms of Voluntary Cooperation across Culturally Diverse Societies: Evidence from the US, the UK, Morocco, and Turkey We examine the role of cooperative preferences, beliefs, and punishments to uncover potential cross-societal differences in voluntary cooperation. Using one-shot public goods experiments in four comparable subject pools from the US and the UK (two similar Western societies) and Morocco and Turkey (two comparable non-Western societies), we find that cooperation is lower in Morocco and Turkey than in the UK and the US. Using the ABC approach – in which cooperative attitudes and beliefs explain cooperation – we show that cooperation is mostly driven by differences in beliefs rather than cooperative preferences or peer punishment, both of which are similar across the four subject pools. Our methodology is generalizable across subject pools and highlights the central role of beliefs in explaining differences in voluntary cooperation within and across culturally, economically, and institutionally diverse societies. Because our behavioral mechanisms correctly predict actual contributions, we argue that our approach provides a suitable methodology for analyzing the determinants of voluntary cooperation of any group of interest. JEL Classification: C9, H4, C7, D2
Bacterial Contamination on Reusable Pulse Oximeter Sensors in Intensive Care Units and Its Manual Disinfection by Alcohol and Sodium Hypochlorite

: Nosocomial infections may result from intensive care unit pulse oximeters. The descriptive study examined pulse oximeter sensor microbiological contamination and the efficacy of manual disinfection with alcohol and sodium hypochlorite in five hospital intensive care units. Sixty-eight reusable pulse oximeter sensors were swabbed, cultured, and evaluated after decontamination. In private and public hospitals, 12 (35.2%) and 13 (37.2%) pulse oximeters tested positive for bacteria. Alcohol 70% reduced the microbial load and more than 10% sodium hypochlorite. The study found that purposeful cleaning and disinfection reduce microorganisms. Alcohol was more efficacious than sodium hypochlorite. Critical care facilities should regularly clean reusable pulse oximeter sensors.
Available cloned genes and markers for genetic improvement of biotic stress resistance in rice

Biotic stress is one of the major threats to stable rice production. Climate change affects the shifting of pest outbreaks in time and space. Genetic improvement of biotic stress resistance in rice is a cost-effective and environment-friendly way to control diseases and pests compared to other methods such as chemical spraying. Fast deployment of the available and suitable genes/alleles in local elite varieties through marker-assisted selection (MAS) is crucial for stable high-yield rice production. In this review, we focused on consolidating all the available cloned genes/alleles conferring resistance against rice pathogens (virus, bacteria, and fungus) and insect pests, the corresponding donor materials, and the DNA markers linked to the identified genes. To date, 48 genes (independent loci) have been cloned for only major biotic stresses: seven genes for brown planthopper (BPH), 23 for blast, 13 for bacterial blight, and five for viruses. Physical locations of the 48 genes were graphically mapped on the 12 rice chromosomes so that breeders can easily find the locations of the target genes and distances among all the biotic stress resistance genes and any other target trait genes. For efficient use of the cloned genes, we collected all the publically available DNA markers (~500 markers) linked to the identified genes. In case of no available cloned genes yet for the other biotic stresses, we provided brief information such as donor germplasm, quantitative trait loci (QTLs), and the related papers. All the information described in this review can contribute to the fast genetic improvement of biotic stress resistance in rice for stable high-yield rice production.
Carbon forms and functions in forest soils.

Based on the papers presented at the Eighth North American Forest Soils Conference; and sponsored by the Soil Science Society of America, Society of American Foresters, Canadian Institute of Forestry, and Canadian Soil Science Society. Financial support provided by USDA Forest Service-Global Climate Change Program, ITFRayonier, Inc., Packaging of America, Georgia Pacific, Container Corporation of America-Jefferson Smurfit Corporation, Champion International Corporation, International Paper Company, and University of Florida-Institute of Food and Agricultural Sciences; Gainsville, Florida, May 1993.
Prediction of Cotton Yarn Quality Based on Attention-GRU

With the diversification of spinning order varieties and process parameters, the conventional method of determining production plans through trial spinning no longer satisfies the processing requirements of enterprises. Currently, deficiencies exist in predicting spinning quality relying on manual experience and traditional methods. The back propagation (BP) neural network within the realm of deep learning theory faces challenges in handling time series data, while the long short-term memory (LSTM) neural network, despite its intricate mechanism, exhibits an overall lower predictive accuracy. Consequently, a more precise predictive methodology is imperative to assist production personnel in efficiently ascertaining cotton-blending schemes and processing parameters, thereby elevating the production efficiency of the enterprise. In response to this challenge, we propose an attention-GRU-based cotton yarn quality prediction model. By employing the attention mechanism, the model is directed towards the input features most significantly impacting yarn quality. Real-world performance indicators of raw cotton and process parameters are utilized to predict yarn tensile strength. A comparative analysis is conducted against prediction results of BP, LSTM, and gated recurrent unit (GRU) neural networks that do not incorporate the attention mechanism. The outcomes reveal that the GRU model enhanced with the attention mechanism demonstrates reductions of 56.3%, 38.5%, and 36.4% in root mean square error (RMSE), along with 0.367%, 0.158%, and 0.190% in mean absolute percentage error (MAPE), respectively. The model attains a coefficient of determination R-squared of 0.954, indicating a high degree of fitness. This study underscores the potential of the proposed attention-GRU model in refining cotton yarn quality prediction and its consequential implications for process optimization and enhanced production efficiency within textile enterprises.
Investigaciones arqueológicas en el delta del Diquís

El valle del curso inferior del rio Terraba (suroeste de Costa Rica), llamado tambien delta del Diquis, es famoso por sus grandes esferas de piedra y su escultura original. Exceptuando los trabajos de Stone (1945) y Lothrop (1963), nuestra informacion sobre la arqueologia de la region se limitaba a producto del saqueo por huaqueros atraidos desde mas de un siglo por los objetos de oro de los entierros precolombinos. En 1990, se llevo a cabo en el delta una prospeccion sistematica con el fin de evaluar la densidad y la duracion del poblamiento. Gracias al reconocimiento y a la secuencia ceramica obtenida que comprendre tres fases Camibar, Sierpe y Palmar , sabemos que la region, ocupada por los menos desde 600dC, era densamente poblada entre 800 y 1200 d C. Sostenia contactos frecuentes, tanto por mar como por tierra, con sus vecinos del norte y del sur. A juzgar por el alto nivel tecnico alcanzado por sus orfebreros, escultores y alfareros en la ultima parte de su historia, se considera en delta como un centro mayor de produccion dentro del Gran Chiriqui.
Marine protected areas of the Victorian embayments bioregion part 1 : Port Phillip Bay

Along Victoria’s coastline there are 30 Marine Protected Areas (MPAs) that have been established to protect the state’s significant marine environmental and cultural values. These MPAs include 13 Marine National Parks (MNPs), 11 Marine Sanctuaries (MSs), 3 Marine and Coastal Parks, 2 Marine Parks, and a Marine Reserve, and together these account for 11.7% of the Victorian marine environment. The highly protected Marine National Park System, which is made up of the MNPs and MSs, covers 5.3% of Victorian waters and was proclaimed in November 2002. This system has been designed to be representative of the diversity of Victoria’s marine environment and aims to conserve and protect ecological processes, habitats, and associated flora and fauna. The Marine National Park System is spread across Victoria’s five marine bioregions with multiple MNPs and MSs in each bioregion, with the exception of Flinders bioregion which has one MNP. All MNPs and MSs are “no-take” areas and are managed under the National Parks Act (1975) - Schedules 7 and 8 respectively. This report updates the first Marine Natural Values Study (Plummer et al. 2003) for the MPAs in the Port Phillip Bay area of the Victorian Embayments bioregion and is one of a series of five reports covering Victoria’s Marine National Park System. It uses the numerous monitoring and research programs that have increased our knowledge since declaration and aims to give a comprehensive overview of the important natural values of each MNP and MS.