Miracle-dz/UniFAR-FTUs huggingface dataset:
Unveiled chromosomal diversity in the Araneidae (Araneomorphae): the highest diploid number among entelegynes and the first record of the X1X2X3X4 Sex Chromosome System in the family

Abstract. The Araneidae is among the most speciose spider families, but there are few karyotype studies (1.9%) and some species-rich clades are without any chromosomal study. Understanding the evolution of chromosome number and Sex Chromosome Systems is made more difficult by many uncertain evolutionary relationships within the family. In this work, the chromosomal analysis of eight araneid species (Acacesia benigna Glueck, 1994, Actinosoma pentacanthum (Walckenaer, 1841), Alpaida bicornuta (Taczanowski, 1878), Dubiepeira Levi, 1991 sp. , Gasteracantha cancriformis (Linnaeus, 1758), Parawixia bistriata (Rengger, 1836), Verrucosa meridionalis (Keyserling, 1892) and Verrucosa scapofracta Lise, Kesster & Silva, 2015), contribute to discussions of some evolutionary scenarios of chromosome evolution. The gonads were submitted to colchicine treatment, hypotonization, slide preparation, and Giemsa staining. The species analyzed showed 2n♂ = 24 (11II + X1X2), except Dubiepeira sp. with 2n♂ = 41 (19II + X1X2X3), and both Verrucosa species, which presented 2n♂ = 47 (22II + X1X2X3) in V. meridionalis and 2n♂ = 50 (23II + X1X2X3X4) in V. scapofracta. The species analyzed possess all chromosomes with acro/telocentric chromosomal morphology. The 2n♂ = 24, X1X2 found in most species studied here is the most frequent karyotype in the Araneidae. This study presents the first chromosomal data for the diverse clade “Micrathenines”, the highest diploid number among entelegynes (2n♂ = 50), and the first record of an X1X2X3X4 in the Araneidae. The chromosome data suggest a series of fission events in the origin of Verrucosa karyotypes, and a close relationship between Dubiepeira sp. and Araneus ventricosus (L. Koch, 1878). Moreover, Alpaida bicornuta can be cytotaxonomically distinguished of other Alpaida species karyotyped up to now.
PROPUESTA DE UNA METODOLOGÍA DE CÁLCULO PARA EL DISEÑO PRELIMINAR DE UN FILTRO COALESCENTE

This paper describes coalescing filters which are one of the equipments for most efficient capture and recovery of mist. They are inexpensive and have fewer limitations in their application, regarding other options on the market. This research clarifies the operation equations that model them and describes ideal characteristics of filter media. It also proposes a methodology for design and scale-up of this type of equipment for liquid recovery, supposing experimental data is available, in order to guide the reader in coalescing filter making.
Integration levels of management systems Quality, Safety and Environment: Case of Moroccan companies

The objective of this paper is to analyze the levels of integration management systems (Quality, safety, environment, .). The study was conducted through an empirical survey administered online from 50 doubling or tripling Moroccan companies certified ISO 9001, ISO 14001, OHSAS 18001, etc. Levels of integration were first studied in relation to the order of implementation management systems and depending on the number of certificates held by each company.The results show that the level of integration of management systems is higher when the company adopts an integrated management system directly from the first move by against those implemented management systems sequentially months have high levels of integration. Companies that are doubly certified have higher levels of integration than those certified triple.The investigation to uncover the levels of integration of management systems with the Moroccan companies, it has responded to the issues raised by this publication.
Thin-film microstrip lines and coplanar waveguides on semiconductor substrates for sub-mm wave frequencies

It is shown that both thin-film microstrip lines (TFMSLs) and miniaturized coplanar waveguides (CPWs) offer low-dispersive propagation properties up to 1 THz. At the same time, they are fully compatible with monolithic integration. Radiation and dispersion effects are discussed and basic rules are presented how CPWs should be designed in order to reach the desired sub-mm-wave performance. Index Terms – thin-film microstrip line, coplanar waveguide, MMIC, modeling
Managing the government of Tanzania: Is Kikwete on the right track in conforming to the millennium development goals?

Millennium development goals have become a pillar in cognising good or bad governance. Most governments, today appeal for fulfilment of the MDG because partly they give a signal on the extent to which development is going to be attained. This article presents an assessment of the extent to which the government of Tanzania under the leadership of Dr. Jakaya Mrisho Kikwete has fulfilled the MDG. The article utilises documentation as the data collection strategy. It has further done some comparative analysis of the pace of attainment of the Goals versus past regimes of the same country. The paper concludes that, so far, the fourth regime has done the best in achieving what is disclosed in the Development Millennium Goals. Most goals have become evident to the people of Tanzania, and that just like marketing is crucial for various new products, governments must learn to market what they have achieved.
Contactless Credit Cards Payment Fraud Protection by Ambient Authentication

In recent years, improvements to the computational ability of mobile phones and support for near-field-communication have enabled transactions to be performed by using mobile phones to emulate a credit card or by using quick response codes. Thus, users need not carry credit cards but can simply use their mobile phones. However, the Europay MasterCard Visa (EMV) protocol is associated with a number of security concerns. In contactless transactions, attackers can make purchases by launching a relay attack from a distance. To protect message transmission and prevent relay attacks, we propose a transaction protocol that is compatible with EMV protocols and that can perform mutual authentication and ambient authentication on near-field-communication-enabled mobile phones. Through mutual authentication, our protocol ensures the legitimacy of transactions and establishes keys for a transaction to protect the subsequent messages, thereby avoiding security problems in EMV protocols, such as man-in-the-middle attacks, skimming, and clone attacks on credit cards. By using ambient factors, our protocol verifies whether both transacting parties are located in the same environment, and it prevents relay attacks in the transaction process.
Acupoint Catgut-Embedding Therapy Inhibits NF-κB/COX-2 Pathway in an Ovalbumin-Induced Mouse Model of Allergic Asthma

Allergic asthma is associated with T helper (Th) 2 cell-biased immune responses and characterized by the airway hyperresponsiveness (AHR). Studies have shown that the acupoint catgut-embedding therapy (ACE) has a therapeutic effect on allergic asthma. However, the relevant mechanism is poorly understood. In present study, female BALB/c mice were sensitized and challenged with ovalbumin (OVA) to establish a model of allergic asthma. AHR was evaluated by using airway resistance (RL) and lung dynamic compliance (Cdyn). Airway inflammation and mucus hypersecretion were observed by HE and PAS staining. Inflammatory cells were counted, and related cytokines in bronchoalveolar lavage fluid (BALF) were detected by enzyme-linked immunosorbent assay (ELISA). Pulmonary group 2 innate lymphoid cell (ILC2s) proportions were analyzed by flow cytometry. The expression of nuclear factor κB (NF-κB) and cyclooxygenase-2 (COX-2) was detected by immunostaining. Our results showed that OVA induction resulted in a significant increase in RL, accompanied by a significant decrease in Cdyn. The levels of interleukin- (IL-) 4, IL-13, OVA-specific IgE in BALF, and the percentage of ILC2 in the lungs were markedly increased accompanied by a significant decreased in interferon-γ (IFN-γ). Furthermore, the expressions of p-NF-κB p65 and COX-2 in airways were significantly upregulated. After ACE treatment, the indicators above were significantly reversed. In conclusion, ACE treatment inhibited the secretion of Th2 cytokines and the proliferation of ILC2s in the lungs, thereby dampening the inflammatory activity in allergic asthma. The underlying mechanism might be related to the inhibition of NF-κB/COX-2 pathway.
Strain Rate Imaging Using Two-Dimensional

of the time derivative of the strain magnitude (i.e., square root of the strain intensity). Such images complement traditional tissue velocity images (TVI), providing a more complete description of cardiac mechanics. To test the proposed approach, SRI were both simulated and measured on a thickwalled, cylindrical, tissue-equivalent phantom modeling cardiac deformations. Real-time ultrasound images were captured during periodic phantom deformation, where the period was matched to the data capture rate of a commercial scanner mimicking high frame rate imaging of the heart. Simulation results show that SRI with spatial resolution between 1 and 2 mm are possible with an array system operating at 5 MHz. Moreover, these images are virtually free of angle-dependent artifacts present in TVI and simple strain rate maps derived from these images. Measured results clearly show that phantom regions of low deformation, which are difficult to identify on tissue velocity-derived SRI, are readily apparent with SRI generated from twodimensional phase-sensitive speckle tracking.
The Current Sensors in Power Electronics, a Review

Abstract Current sensors are widely used in all the fields of electrical engineering and power conversion. The applications are very diverse: current measurements in semiconductors, current sensing for variable speed drive, current measurement in high voltage networks. These examples show the great diversity of performances, electrical constraints and environmental constraints of these sensors. In this paper a state-of-the-art is presented about the main types of sensors, so that the user can optimise his choice with respect to the problem to solve.
Optimized placement of symmetrical service function chain in network function virtualization

Network function virtualization (NFV) is one of the key technology enablers for actualizing 5G networks. With NFV, virtual network functions (VNFs) are linked together as a service function chain (SFC), which provides network functionality for the customer on demand. However, how to efficiently find a suitable placement for VNFs regarding the given objectives is an extremely difficult issue. The existing approaches assume that the SFC has a simple and asymmetrical pattern that is unsuitable to modeling a real system. We address this limitation by studying a VNF placement optimization problem with symmetrical SFCs that can support both symmetric and asymmetric traffic flows. This NP-hard problem is formulated as a mixed-integer linear programming (MILP) model. An iterative greedy-based heuristic is proposed to overcome the complexity of the MILP model. Extensive simulation results show that the proposed heuristic can obtain a near-optimal solution compared to MILP for a small-scale network, and at the same time, is superior to a traditional heuristic for a large-scale network.
Successful Management of Pheochromocytoma Crisis with Cardiogenic Shock by Percutaneous Left Ventricular Assist Device

Therapeutic strategy utilizing mechanical circulatory supports in patients with pheochromocytoma-related cardiogenic shock remains unestablished. We had a 51-year-old man with acute decompensated heart failure due to pheochromocytoma crisis. He received a percutaneous left ventricular assist device-supported alpha-blocker and intensive fluid infusion therapy, which ameliorated impaired end-organ dysfunction, maintaining hemodynamics and achieving cardiac recovery, followed by the successfully scheduled adrenalectomy. Early suspicion of pheochromocytoma and Impella-supported disease-specific medical management might be a promising bridge to surgery strategy.
Impairment of NK Cell Mediated Immune Surveillance Against Acute Myeloid Leukemia

SUMMARY Natural killer (NK) cells are cytotoxic lymphocytes contributing in innate immune responses that recognize and kill virus-infected and tumor cells without prior stimulation. Several clinical trials have indicated that NK cell-based immunotherapy represents a promising antitumor immunotherapeutic approach due to their key role in mediating graft versus leukemic effect against hematological malignancies, particularly acute myeloid leukemia. However, the antitumor activity of NK cells is inhibited as a result to immune-evasion mechanisms developed by malignant cells through alterations in the expression of activating and inhibitory receptors and their ligands, as well as secretion of soluble NK-inhibitory mediators. Until now, the exact molecular mechanisms involved in these alterations are still not defined.
Experimental investigation of spillover effect in system of active vibration control

Piezoelectric actuators are widely used in structural systems for active vibration control with the aim to enhance the performance of systems. The developed system of active vibration control consists of active structure, controller and high voltage amplifier. In this paper, the composite beam is host structure for sensor platform (strain gages) and actuator platform (dual layer PZT piezoelectric actuator). In order to improve the dynamic characteristics of active system, the coefficients of PID controller are changed. The effectiveness of active vibration control system at mode of interest can be improved with change of PID coefficients, but the stability of system can be reduced. The instability of the active structure is often perturbed by spillover effect. In this paper the importance of considering spillover effects in closed loop of piezoelectric active structures is demonstrated and shown the importance of change the PID coefficients in stability of active vibration control system. Experimental results which correspond to the developed active vibration control system are presented and affirmed stability on proposed active structure.
Isolation, Selection and Characterization of Wild Yeasts with Potential for Brewing

Abstract Ninety-two wild yeasts were isolated from different fruits, for possible use in brewing, using the technological traits of carbohydrate fermentation and hydrogen sulfide production. Twelve yeasts were selected for identification by sequencing (D1/D2 domain or ITS1-5.8S-ITS2 region) and their volatile compounds production analyzed using gas chromatography. From these analyses, three yeasts were chosen for further characterization and beer production. Strains were characterized by their tolerance to osmotic and ethanol stress, their flocculation profile, growth at different temperatures, apparent attenuation (percentage of sugars converted into alcohol), estimated ABV (alcohol by volume) and reducing sugar profile. Beers were analyzed for alcohol content and sensorial analysis. The isolates CL011 and PB111 (Saccharomyces cerevisiae) and CB341 (Wickerhamomyces anomalus) showed promising properties for brewing, which included high production of interesting volatile compounds (esters, terpenes, lactones, and C13-norisoprenoids) by CL011, a neutral profile by PB111, and the production of non-classic beer volatile compounds by CB341 in a mixed culture. Supplemental data for this article is available online at https://doi.org/10.1080/03610470.2022. 2031777 .
Towards a mobile motion analysis laboratory: Improvements in wearable motion capture and force measurement

Gait analysis is an important tool for diagnosing a wide variety of disorders, with its increasingly accepted benefits culminating in the widespread adoption of motion analysis laboratories. A modern analysis laboratory consists of a multicamera marker tracking system for 3D reconstruction of kinematics and multiple high-fidelity load transducers to determine ground reaction force and enable inverse-dynamics for biomechanics. There is a need for an alternative motion analysis system which does not require a fixed laboratory setting and is lower in cost; freeing the motion capture from the laboratory and reducing the technology costs would enable long-term, home-based, natural monitoring of subjects. This thesis describes two contributions to the end goal of an inexpensive, mobile, insole-based motion analysis laboratory. First is the application of an inertialmeasurement-unit calibration routine and zero-velocity-update algorithm to improve position and orientation tracking. Second is the development, from basic sensor to prototype, of an insole capable of measuring 3 degree-of-freedom ground reaction force. These contributions represent a proof-of-concept that quantitative gait analysis, complete with dynamics, is possible with an insole-based system. To my grandfather Arthur Dalton, who showed me that you can, and must, do everything with a smile.
Homicide in Australia 2019-20

The National Homicide Monitoring Program is Australia’s only national data collection on homicide incidents, victims and offenders. This report describes the 261 homicide incidents recorded by Australian state and territory police between 1 July 2019 and 30 June 2020. During this 12-month period there were 278 victims of homicide and 314 identified offenders.
The Protective Effects of Hydrogen Sulfide New Donor Methyl S-(4-Fluorobenzyl)-N-(3,4,5-Trimethoxybenzoyl)-l-Cysteinate on the Ischemic Stroke

In this paper, we report the design, synthesis and biological evaluation of a novel S-allyl-l-cysteine (SAC) and gallic acid conjugate S-(4-fluorobenzyl)-N-(3,4,5-trimethoxybenzoyl)-l-cysteinate (MTC). We evaluate the effects on ischemia-reperfusion-induced PC12 cells, primary neurons in neonatal rats, and cerebral ischemic neuronal damage in rats, and the results showed that MTC increased SOD, CAT, GPx activity and decreased LDH release. PI3K and p-AKT protein levels were significantly increased by activating PI3K/AKT pathway. Mitochondrial pro-apoptotic proteins Bax and Bim levels were reduced while anti-apoptotic protein Bcl-2 levels were increased. The levels of cleaved caspase-9 and cleaved caspase-3 were also reduced in the plasma. The endoplasmic reticulum stress (ERS) was decreased, which in turns the survival rate of nerve cells was increased, so that the ischemic injury of neurons was protected accordingly. MTC activated the MEK-ERK signaling pathway and promoted axonal regeneration in primary neurons of the neonatal rat. The pretreatment of MEK-ERK pathway inhibitor PD98059 and PI3K/AKT pathway inhibitor LY294002 partially attenuated the protective effect of MTC. Using a MCAO rat model indicated that MTC could reduce cerebral ischemia-reperfusion injury and decrease the expression of proinflammatory factors. The neuroprotective effect of MTC may be due to inhibition of the over-activation of the TREK-1 channel and reduction of the current density of the TREK1 channel. These results suggested that MTC has a protective effect on neuronal injury induced by ischemia reperfusion, so it may have the potential to become a new type of neuro-ischemic drug candidate.
Real-time identification for ground vehicle trajectory estimation using extended Kalman filter residual analysis

This thesis describes real-time model identification for ground vehicle trajectory estimation by means of the Automatic Dynamic Trajectory Recognition System. A theoretical approach to trajectory model identification for the ADTR system using Kalman filter residual analysis is developed. This approach selects the best trajectory model from an array of candidates by comparing residual vectors generated by a bank of Kalman filter estimators built upon the candidate models. The filter with the lowest RMS residual magnitude value is identified as containing the best trajectory model. The system is implemented in Draper Laboratory's C-Sim simulation environment. The system simulation contains a sensor model as well as a dynamic model of the ground vehicle. The simulation results demonstrate a correlation between the RMS value of the filter residual magnitude and the RMS magnitude of the ground vehicle position prediction error of extrapolating four seconds into the future. The results support the model identification approach. Thesis Advisor: Derek Rowell Professor of Mechanical Engineering Thesis Supervisor: Edward J. Lanzilotta Charles Stark Draper Laboratory
Response to Letter to the Editor from Zandee and Links: “Metastatic Differentiated Thyroid Cancer Survival Is Unaffected by Mode of Preparation for 131I Administration”

Response to Letter to the Editor from Zandee and Links: “Metastatic Differentiated Thyroid Cancer Survival Is Unaffected by Mode of Preparation for I Administration” Cristiane J. Gomes-Lima, Sanjita Chittimoju, Leen Wehbeh, Sunita Dia, Prathyusha Pagadala, Mohammad Al-Jundi, Sakshi Jhawar, Eshetu Tefera, Mihriye Mete, Joanna Klubo-Gwiezdzinska, Douglas Van Nostrand, Jacqueline Jonklaas, Leonard Wartofsky, and Kenneth D. Burman MedStar Clinical Research Center, MedStar Health Research Institute (MHRI), Hyattsville, MD 20782-2031, USA Section of Endocrinology, MedStar Washington Hospital Center, Washington, DC 20010, USA Department of Internal Medicine, MedStar Washington Hospital Center, Washington, DC 20010, USA Department of Internal Medicine, Sinai Hospital of Baltimore, Research Volunteer, Baltimore, MD 21215, USA Department of Biostatistics, MedStar Health Research Institute (MHRI), Hyattsville, MD 20782-2031, USA Thyroid Tumors and Functional Thyroid Disorders Section, National Institutes of Health/National Institute of Diabetes and Digestive and Kidney Diseases (NIH/NIDDK), Bethesda, MD 20892, USA Nuclear Medicine Research, MedStar Washington Hospital Center, Washington, DC 20010, USA Division of Endocrinology, Department of Medicine, Georgetown University, Washington, DC 20057, USA Correspondence: Cristiane J. Gomes-Lima, MD, PhD, SHIS QI 23 Conj. 4 number 19, 71.660-040 Brasília, DF, Brazil. Email: cjglima@gmail.com.
Distinct Firing Activities of the Hypothalamic Arcuate Nucleus Neurons to Appetite Hormones

The hypothalamic arcuate nucleus (Arc) is a central unit that controls the appetite through the integration of metabolic, hormonal, and neuronal afferent inputs. Agouti-related protein (AgRP), proopiomelanocortin (POMC), and dopaminergic neurons in the Arc differentially regulate feeding behaviors in response to hunger, satiety, and appetite, respectively. At the time of writing, the anatomical and electrophysiological characterization of these three neurons has not yet been intensively explored. Here, we interrogated the overall characterization of AgRP, POMC, and dopaminergic neurons using genetic mouse models, immunohistochemistry, and whole-cell patch recordings. We identified the distinct geographical location and intrinsic properties of each neuron in the Arc with the transgenic lines labelled with cell-specific reporter proteins. Moreover, AgRP, POMC, and dopaminergic neurons had different firing activities to ghrelin and leptin treatments. Ghrelin led to the increased firing rate of dopaminergic and AgRP neurons, and the decreased firing rate of POMC. In sharp contrast, leptin resulted in the decreased firing rate of AgRP neurons and the increased firing rate of POMC neurons, while it did not change the firing rate of dopaminergic neurons in Arc. These findings demonstrate the anatomical and physiological uniqueness of three hypothalamic Arc neurons to appetite control.