Miracle-dz/UniFAR-FTUs huggingface dataset:
Noise-Like Features-Assisted GNSS Spoofing Detection Based on Convolutional Autoencoder

The global navigation satellite system (GNSS) is susceptible to spoofing, limiting its uses for national security. As a solution to this problem, this article modeled the GNSS spoofing detection (GNSS-SD) problem as a one-class novelty detection (OND) problem and developed a framework with high accuracy and rapid response for GNSS-SD in the postcorrelation domain. Specifically, based on the radio frequency fingerprints (RFFs) of transmitters, this framework utilized three steps to detect spoofing: noise-like feature construction, anomaly score calculation, and adaptive threshold decision-making. To verify the effectiveness of the proposed framework, we performed three comparative experiments using the University of Texas dataset. Compared with traditional signal quality monitoring (SQM) methods, the proposed framework achieved an accuracy of over 99.7%, representing a 14% improvement in complex spoofing scenarios. Besides, it won an accuracy exceeding 4% of the artificial intelligence methods in the existing literature under the same GNSS spoofing scenarios. In addition, in dynamic scenarios with multipath effects, the 93.2% accuracy demonstrated the generality of the proposed framework. Furthermore, the experiments revealed that 96.7% of spoofing can be successfully detected by the framework within a 30-s timeframe.
Periodic Limb Movements during Sleep in Acute Stroke: Prevalence, Severity and Impact on Post-Stroke Recovery

Background: Periodic Limb Movements during Sleep (PLMS) have been described to be frequently present in stroke patients. We aimed to evaluate the prevalence and severity of PLMS in acute stroke patients and clarify the association between PLMS and coexisting Sleep Disordered Breathing (SDB). Additionally, we focused on identifying variables that could independently predict the presence of PLMS in patients with acute stroke. The potential impact of PLMS on stroke outcome at three months was investigated as well. Methods: In this study, we performed overnight polysomnography on consecutive stroke patients within 72 h from symptom onset. Data regarding clinical and imaging characteristics were prospectively collected. National Institute of Health Stroke Scale (NIHSS), modified Rankin Scale (mRS) and Epworth-Sleepiness Scale (ESS) were used to evaluate stroke severity on admission, stroke outcome at three months and history of daytime sleepiness, respectively. We documented PLMS and SDB using standard polysomnography criteria. Results: We prospectively assessed 126 patients with acute stroke [109 with ischemic and 17 with hemorrhagic stroke, mean age 60 ± 11 years, 68% men, median NIHSS score on admission: 3 (IQR: 2–7)]. The overall rate of PLMS in our cohort was 76%, and the rate of SDB among patients with PLMS was 83%. PLMS detection rates differed significantly (p-value: <0.001) according to SDB, with PLMS prevalence increasing with greater SDB severity. SDB could independently (OR:4.869, 95% CI: 1.884–12.784, p-value: 0.001) predict the presence of PLMS in the acute stroke phase in multivariable analyses adjusting for potential confounders. Moreover, baseline stroke severity (NIHSS-score increase in per-1 point: OR: 0.819, 95% CI: 0.737–0.895, p-value < 0.001) and PLMS (OR:0.099, 95% CI: 0.009–0.482, p-value = 0.015) were significantly associated with the likelihood of excellent functional outcome (mRS-scores: 0–1) at 3 months. Conclusion: The common presence of mostly severe PLMS in patients with acute stroke and their negative effect on stroke outcomes point out the necessity for early PLMS detection and treatment.
Analysis of Characteristics and Medication Profile of Dengue Hemorrhagic Fever Patients in Children at the Inpatient Installation of

Dengue hemorrhagic fever (DHF) is an acute viral infectious disease caused by the dengue virus. In general, DHF treatment is supportive and symptomatic. Supportive treatment is administering replacement fluids for the body, such as intravenous fluids. As symptomatic therapy, paracetamol can be given as an antipyretic. This study aimed to determine the characteristics and treatment profile of pediatric patients diagnosed with DHF at the inpatient installation of Samarinda Medika Citra Hospital in 2020-2021. The research method used is observational research which will then be described descriptively. Based on the results of the characteristics of most patients, namely in male patients (62.4%) with school-age patients (6-18 years) (80%), the degree of severity experienced by DHF pediatric patients is degree 1 of (78, 4%) with an average length of stay of 4 days (28.8%) the average weight of pediatric patients with DHF is 20-<40kg (56.8%). The most common clinical symptom experienced by patients was nausea and vomiting (34.8%). The management given to patients was supportive therapy (100%) and symptomatic therapy of antipyretic (17.4%), antibiotic (8.7%), antiulcer (8.7%), and antiemetic (8.6%). This study concludes that the most widely administered supportive treatment is rehydration therapy, while symptomatic therapy, namely antipyretic-analgesic and antiulcer.
A learning algorithm for elementary formal systems and its experiments on identification of transmembrane domains

Proposes a method for algorithmic learning of transmembrane domains based on elementary formal systems. An elementary formal system (EFS) is a kind of a logic program consisting of if-then rules. With this framework, the authors have implemented the algorithm for identifying transmembrane domains in amino acid sequences. Because of the limitations on computational resources, they restrict candidate hypotheses to EFSs defined by collections of regular patterns. From 70 transmembrane sequences and a similar amount of negative examples which are not transmembrane sequences, the algorithm has produced several reasonable hypotheses of small size. Experiments with the database PIR show that one of them recognizes 95% of 689 transmembrane sequences and 95% of 19256 negative examples which consist of non-transmembrane sequences of length around 30 randomly chosen from PIR. <<ETX>>
Predictive functional assay‐based classification of PMS2 variants in Lynch syndrome

The large majority of germline alterations identified in the DNA mismatch repair (MMR) gene PMS2, a low‐penetrance gene for the cancer predisposition Lynch syndrome, represent variants of uncertain significance (VUS). The inability to classify most VUS interferes with personalized healthcare. The complete in vitro MMR activity (CIMRA) assay, that only requires sequence information on the VUS, provides a functional analysis‐based quantitative tool to improve the classification of VUS in MMR proteins. To derive a formula that translates CIMRA assay results into the odds of pathogenicity (OddsPath) for VUS in PMS2 we used a set of clinically classified PMS2 variants supplemented by inactivating variants that were generated by an in cellulo genetic screen, as proxies for cancer‐predisposing variants. Validation of this OddsPath revealed high predictive values for benign and predisposing PMS2 VUS. We conclude that the OddsPath provides an integral metric that, following the other, higher penetrance, MMR proteins MSH2, MSH6 and MLH1 can be incorporated as strong evidence type into the upcoming criteria for MMR gene VUS classification of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology (ACMG/AMP).
Rural and historic tourism potential of Seceani from Timis county, Banat region

This paper intends to underline the unknown natural andhistorical resources of Seceani, one of the smallest and until recentlyisolated villages in Timis County, Orţisoara Commune, Banat, Romania. Twoare the objectives with great natural tourism potential in the commune: theresource of geothermal water and the muddy volcanoes. Their exploitation wouldensure the economical development of the area, as well as the experimentationof alternative tourism, such as ecotourism and therapeutic tourism. Besidesthis, there is also the vicinity of the biggest Bronze Age Fortification fromCornesti and a medieval fortress just in the centre of the village. Thepromotion of a rural and historic tourism in Seceani will enhance the progressof the area and also will increase the image of Banat, as a tourism destinationnot only in Romania, but in all Europe and even further. Its purpose may be toeducate the traveler, to provide funds for ecological conservation, to directlybenefit the economic development and political empowerment of this localcommunity, or to foster respect for the authentic Banat culture and mentality.
THEORETICAL ANALYSIS ON THE NON-LINEAR ELASTIC PROPERTIES OF THE AORTIC ARCH WALL

血管壁非线性力学特性是探索心血管中的血液流动规律及脉搏波传播现象的一个重要前提．在血管力学研究中，直管动脉壁的本构方程已有相当深人的研究，唯独象主动脉弓那样的弯管动脉壁本构方程；至今还没有建立一个理论模型．文中在已有的直管动脉壁本构方程研究基础上，提出一个理论方法来分析弯曲动脉壁的非线性弹性力学性质，在弯曲动脉壁被模拟为均质、正交各向异性、不可压缩材料的前提下，作者从理论上建立了一个表达弯管动脉壁非线性弹性性质的三维ｅ指数型本构方程文中还探讨了弯曲动脉壁内的残余应变分析．
Citations Prize 2009

Physics in Medicine & Biology (PMB) awards its 'Citations Prize' to the authors of the original research paper that has received the most citations in the preceding five years (according to the Institute for Scientific Information (ISI)). The lead author of the winning paper is presented with the Rotblat Medal (named in honour of Professor Sir Joseph Rotblat who was the second—and longest serving—Editor of PMB, from 1961–1972). The winning co-authors each receive a certificate. Some of the winning authors with their certificates, and Christian Morel with the Rotblat Medal, at the award ceremony in Orsay, near Paris. From left to right are Corinne Groiselle, Lydia Maigne, David Brasse, Irène Buvat, Dimitris Visvikis, Giovanni Santin, Uwe Pietrzyk, Pierre-François Honore, Christian Morel, Sébastien Jan and Arion Chatziioannou. The winner of the 2009 Citations Prize for the paper which has received the most citations in the previous 5 years (2004–2008) is GATE: a simulation toolkit for PET and SPECT Authors: S Jan, G Santin, D Strul, S Staelens, K Assié, D Autret, S Avner, R Barbier, M Bardiès, P M Bloomfield, D Brasse, V Breton, P Bruyndonckx, I Buvat, A F Chatziioannou, Y Choi, Y H Chung, C Comtat, D Donnarieix, L Ferrer, S J Glick, C J Groiselle, D Guez, P-F Honore, S Kerhoas-Cavata, A S Kirov, V Kohli, M Koole, M Krieguer, D J van der Laan, F Lamare, G Largeron, C Lartizien, D Lazaro, M C Maas, L Maigne, F Mayet, F Melot, C Merheb, E Pennacchio, J Perez, U Pietrzyk, F R Rannou, M Rey, D R Schaart, C R Schmidtlein, L~Simon, T Y Song, J-M Vieira, D Visvikis, R Van de Walle, E Wieörs and C Morel Reference: S Jan et al 2004 Phys. Med. Biol. 49 4543–61 Since its publication in 2004 this article has received over 200 citations. This extremely high figure is a testament to the great influence and usefulness of the work to the nuclear medicine community. More discussion of the winning paper can be found on medicalphysicsweb. Steve Webb Editor-in-Chief Simon Harris Publisher
Application of Pickering emulsion with microcrystalline cellulose in vitamin C double emulsion process with spray drying technology

ABSTRACT This research studies the impacts of microcrystalline cellulose (MCC) concentrations on the physicochemical properties of spray-dried water-in-oil-in-water (W/O/W) vitamin C double emulsion powder Four MCC concentration (1%, 1.5%, 2%, and 2.5%) were used to produce the vitamin C double emulsion powder. The results of the emulsion’s creaming index, flow behaviour index, zeta value, and particle size indicated that these parameters decreased when the MCC concentration increased. Scanning electronic microscopy (SEM) analysis showed that the higher MCC concentration resulted in a smoother surface In general, the MCC concentration increased, the particle size, hygroscopicity, solubility, water content, and water activity of the double emulsion powder decreased. Double emulsion powder containing 2% MCC presented the highest level of antioxidant activity and was mostly stable after storage for 56 days. Before and after drying, transmission electron microscope (TEM) analysis of the morphological characteristics of the liquid emulsion showed that the concentration of 2% MCC in the emulsion could form a W/O/W double emulsion structure. In conclusion, the addition of MCC significantly affect the properties of vitamin C double emulsion.
Sky Glow from Cities: The Army Illumination Model v2

Abstract : The increasing number of people living on earth and the corresponding increase in outdoor lighting has resulted in light pollution a brightening night sky that has obliterated the stars for much of the world s population. However, for military purposes, in particular Night Vision Goggle (NVG) users, this light can allow for detection of targets that might ordinarily not be seen. The amount of light scattered from an urban location at night is a complicated function of light type, output and shielding, ground albedo, and the atmosphere that it must interact with. Clouds and various types of airborne particulates will also vary the amount of light received by NVGs. This report implements and extends the methods of Treanor and Garstang to estimate the light level received outside of urban locations. Clouds effects along with lunar and sky background illumination are included as are relevant data bases.
Evaluation of the Immunological Efficacy of an LNP-mRNA Vaccine Prepared from Varicella Zoster Virus Glycoprotein gE with a Double-Mutated Carboxyl Terminus in Different Untranslated Regions in Mice

Cell-mediated immunity (CMI) plays a key role in the effectiveness of varicella zoster virus (VZV) vaccines, and mRNA vaccines have an innate advantage in inducing CMI. Glycoprotein E (gE) has been used widely as an antigen for VZV vaccines, and carboxyl-terminal mutations of gE are associated with VZV titer and infectivity. In addition, the untranslated regions (UTRs) of mRNA affect the stability and half-life of mRNA in the cell and are crucial for protein expression and antigenic translational efficiency. In this study, three UTRs were designed and connected to the nucleic acid sequence of gE-M, which is double mutated in the extracellular region of gE. Then, mRNA with different nucleic acids was encapsulated in lipid nanoparticles (LNPs), forming three LNP-mRNA VZV vaccines, named gE-M-Z, gE-M-M, and gE-M-P. The immune response elicited by these vaccines in mice was evaluated at intervals of 4 weeks, and the mice were sacrificed 2 weeks after the final immunization. In the results, the gE-M-P group, which retains the nucleic acid sequence of gE-M and is connected to Pfizer/BioNTech’s BNT162b2 UTRs, induced the strongest humoral immune response and CMI. Because CMI is crucial for protection against VZV and for the design of VZV vaccines, this study provides a feasible strategy for improving the effectiveness and economy of future VZV vaccines.
The Increase in Childhood Obesity and Its Association with Hypertension during Pandemics

There has been a major ongoing health impact of the COVID-19 pandemic on children’s lives, including lifestyle and overall health. Enforcement of prevention measures, such as school closures and social distancing, has significantly affected children’s daily routines and activities. This perspective manuscript aims to explore the rise in childhood obesity and its association with hypertension during pandemics. The COVID-19 pandemic has led to significant disruptions in children’s routines, including reduced physical activity, increased sedentary behavior, and changes in dietary patterns. These factors, coupled with the psychological impact of the pandemic, have contributed to an alarming increase in childhood obesity rates. This paper has highlighted the concerning increase in childhood obesity and hypertension during pandemics. The disruptions caused by the COVID-19 pandemic, including reduced physical activity, increased sedentary behaviors, and changes in dietary patterns, have contributed to the rise in these health conditions. It is crucial to recognize the long-term consequences of childhood obesity and hypertension and the urgent need for a comprehensive approach to address them.
Mateda-2.0: Estimation of Distribution Algorithms in MATLAB

Partially supported by the Saiotek and Research Groups 2007-2012 (IT-242-07) programs (Basque Government), TIN2008-06815-C02-01, TIN- 2008-06815-C02-02, TIN2007-62626 and Consolider Ingenio 2010 - CSD2007-00018 projects (Spanish Ministry of Science and Innovation), the CajalBlueBrain project, and the COMBIOMED network in computational biomedicine (Carlos III Health Institute).
Red Blood Cell Distribution Width: A Potential Inexpensive Marker for Disease Activity in Patients with Rheumatic Diseases; Scoping Review

Background Rheumatic diseases encompass a diverse group of autoimmune disorders that affect the joints and connective tissues. The red blood cell distribution width (RDW) has been widely investigated as an inflammatory marker. This scoping review aimed to explore the potential utility of RDW as an inexpensive marker for disease activity in patients with rheumatic diseases. By summarizing the available evidence, we aimed to determine whether RDW can serve as a reliable and accessible indicator of disease activity in these patients. Methods A comprehensive search was systematically performed across electronic databases, encompassing PubMed, Embase, and Web of Science. Studies have explored the relationship between RDW and disease activity in rheumatic diseases. Data extraction focused on the study characteristics, methodologies, and findings related to RDW as a disease activity marker. Results After removing duplicates, the initial search yielded 25 relevant studies. These studies encompassed a variety of rheumatic diseases, with rheumatoid arthritis being the most frequently studied condition. The association between RDW and disease activity was assessed by using various disease activity indices and clinical parameters. While some studies have reported a significant correlation between elevated RDW and disease activity, others have yielded inconclusive results. Conclusion From this review, we concluded that RDW is an inexpensive potential marker for the evaluation of disease activity in rheumatic diseases. RDW is promising as an inexpensive and readily available marker; however, its clinical utility in assessing disease activity in rheumatic conditions warrants more rigorous investigation through well-designed prospective studies.
SEISMIC DAMAGE EVALUATION OF REINFORCED CONCRETE BUILDINGS WITH SLIT WALLS

Purpose – The purpose of this paper is to investigate a reinforced concrete multi-storey building with dissipative structural walls. These walls can improve the behaviour of a tall multi-storey building. Our main objective is to evaluate the damage of a building with dissipative walls in comparison with that of the building with solid walls. Design/methodology/approach In this paper, a comparative nonlinear dynamic analysis between a building with slit walls and then the same building with solid wall is performed by means of SAP2000 software and using a layer model. The solution to increase the seismic performance of a building with structural walls is to create slit zones with short connections in to the walls. The short connections are introduced as a link element with multi-linear pivot hysteretic plasticity behaviour. The hysteretic rules and parameters of these short connections were proposed by the authors and used in this analysis. In this study, we propose to evaluate the damage of a building with reinforced concrete slit walls with short connections using seismic analysis. Findings – Using the computational model created by the authors for the slit wall, a nonlinear dynamic analysis of a multistorey building with slit walls was done. From the results obtained, the advantages of the proposed structural typology are observed. Originality/value – Using a simple computational model, created by the authors, that consume low processing resources and reduces processing time, a nonlinear dynamic analysis on high-rises buildings was done. Unlike other studies on slit walls with short connections, which are focused mostly on the nonlinear dynamic behaviour of the short connections, in this article we take into consideration the whole structural system, wall, connections and frames.
Editorial: Emerging talents in clinical diabetes

COPYRIGHT © 2023 Matafome and Wang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. TYPE Editorial PUBLISHED 11 September 2023 DOI 10.3389/fendo.2023. 1284900
Time‐limited balanced truncation within incremental four‐dimensional variational data assimilation

Four‐dimensional variational data assimilation (4D‐Var) is a data assimilation method often used in weather forecasting. Based on a numerical model and observations of a system, it predicts the system state beyond the last time of measurement. This requires the minimisation of a functional. At each step of the optimisation algorithm, a full nonlinear model evaluation and its adjoint is required. This quickly becomes very costly, especially in high dimensions. For this reason, a surrogate model is needed that approximates the full model well, but requires significantly less computational effort. In this paper, we propose time‐limited balanced truncation to build such a reduced‐order model. Our approach is able to deal with unstable system matrices. We demonstrate its performance in experiments and compare it with α‐bounded balanced truncation, which is an another reduction approach for unstable systems.
Heritage And The Making Of (Trans-)Local Identities: A Case Study From The Curonian Spit (Lithuania)

This chapter tries to understand the process of making local heritage and by this producing (trans-)local identities at different points in history. The northern part of the Curonian Spit (Lithuania), has been characterised by an inconsistent national affiliation in the course of the twentieth century and the resulting change of population. The end of the Second World War brought a brutal end to local life on the Curonian Spit when most of the inhabitants fled the area in fear of the Red Army, joining millions of others fleeing Central and Eastern Europe. In focussing on local heritage production in Soviet times, the chapter has demonstrated that the local history of Curonian people was Lithuanianised and depicted in a Soviet mode of presentation. While the Curonian heritage was depicted in national-socialist terms during the Nazi regime, it was represented through the lens of socialist ideology during Soviet times. Keywords: (trans-)local identity; Curonian Spit; Lithuanian; local heritage production; Nazi regime; Second World War; Soviet regime