Miracle-dz/UniFAR-FTUs huggingface dataset:
Effects of Hormone Replacement Therapy on Systemic Arterial Properties in Post-Menopausal Women

ABSTRACTEFFECTS OF HORMONE REPLACEMENT THERAPY ON SYSTEMIC ARTERIAL PROPERTIES IN POST-MENOPAUSAL WOMENEric Alps Chen, B.S.University of Pittsburgh, 2002Vascular stiffness properties contribute significantly to the arterial system hydraulic load. There is evidence that vascular stiffness plays a role in cardiovascular remodeling and may be an independent cardiovascular risk factor. Menopause accelerates age-associated increase in arterial stiffness and estrogen administration, which has vasodilating properties, can potentially mitigate this post-menopausal increase in stiffness. The present study examined the effects of chronic hormone replacement therapy (HRT) on systemic arterial mechanical properties in 35 post-menopausal women, divided into two groups: those receiving no HRT (Control, n = 25) and those receiving HRT (HRT-all, n = 10). The HRT-all group consisted of two subgroups: estrogen alone (HRT-E, n = 5) and a combination of estrogen and progesterone (HRT-EP, n = 5). Noninvasive data were collected serially at five times: once at the baseline during the first visit and during four subsequent visits after the initiation of the study at 19±1, 108±5, 193±4, and 388±8 days, respectively. Heart rate (HR), stroke volume (SV), and cardiac output (CO) did not change significantly in the control group throughout the study. This was also true for both HRT groups, except for a small decrease in HR at Visits 3 and 4 for the HRT-E group and an increase in CO at Visit 3 in the HRT-EP group. Mean arterial pressure decreased over time in control and both HRT groups, reaching statistical significance at later times (fifth visit). Systemic vascular resistance did not change significantly in control and both HRT groups. Global arterial compliance (AC) was unchanged for the control group but tended to increase in the HRT-all group, although no statistical significance was reached. In contrast, the subgroup analysis revealed that AC increased for the HRT-E subgroup, reaching statistical significance at the fifth visit. Similarly, significant decrements in pulse wave velocity (PWV), an index of regional vascular stiffness, were observed only for the HRT-E group. In conclusion, AC increased (vascular stiffness decreased) in subjects receiving chronic estrogen therapy only. The inclusion of progesterone seems to counteract the estrogen-mediated decrease in vascular stiffness, indicating that the vascular stiffness-associated cardio-protective effects of HRT, if any, may be limited to estrogen administration alone.
Proceeding Series of the Brazilian Society of Computational and Applied Mathematics CFD-DEM simulations in a gas-solid fluidized bed

A gas-solid fluidized bed consists of mixture of gas-solid in which the particles were suspended by an imposed upward flow. In the present paper, we have carried out two dimensional numerical simulations of gas-solid fluidized bed. CFD-DEM (Computational fluid dynamics-discrete element modeling) approach is used to model two phase flow composed of solid particles and gas inside the fluidized bed. It uses Eulerian and Lagrangian methods to solve fluid and solid particles respectively. Gidaspow drag model is used to model the interaction between gas and solid particles. Numerical simulations were carried out for various inlet gas velocities (75 cm/s to 82 cm/s) for the fluidized bed. The aim of the present work to search for linear waves. It is interesting to note that, the amplitude of disturbances increase with the height. Further, it is observed that growth rate of the amplitude of disturbances is linear for vg = 75 cm/s and nonlinear for vg = 78 to 82 cm/s. Keyword: Fluidized bed, Computational fluid dynamics, discrete element modeling,
Proceeding Series of the Brazilian Society of Computational and Applied Mathematics Deterministic Graph Spectral Sparsification

An important technique in data analysis is principal component analysis or PCA. Given a covariance matrix S, in PCA we need to compute the eigenvector associated to a greatest eigenvalue of S in order to determine the direction of the so-called principal components [3]. It is well know that computation of eigenvalues of general matrices is expensive, and therefore, several authors use techniques of numerical approximation [5]. Furthermore, computations are more efficient whenever the matrices are sparse. A technique for constructing sparse matrices (matrices with many zeros) is spectral sparsification, which is a technique from algebraic graph theory [2]. Given a square and symmetric matrix M which is dense (a matrix with few zeros), spectral sparsification approximates M by a sparse matrix M̃ under some well-defined criteria and with no loss of the spectral properties of M . Many other notions of approximation were introduced before, however, we will use an idea of similarity between matrices called spectral sparsification introduced by Spielman and Teng [2]. Two matrices are similar if their respective quadratic Laplacian forms are. More formally, let G = (V,E) be a undirected and weighted graph and let A = (Aab) in Rn×n be its adjacency matrix. We define the Laplacian matrix L = (Lab) of G as
Proceeding Series of the Brazilian Society of Computational and Applied Mathematics Propagation Dynamics of an epidemic of Flaviviridae arbovirus in Complex Networks of Human Beings and Aedes aegypti

In this work, we propose a new epidemics diffusion model to evaluate the migration behavior of dengue in the populations of its hosts and transmitters (man and mosquitos Aedes) to facilitate the search for combat actions to this disease. As a result, an algorithm that takes into account local characteristics (such as the initial number of infected entities or the probability of infection for the spread of the epidemics) and incorporates mobility to the final model was produced, following the simple or compound contact between transmitters and target entities. This paper explores the human and mosquito factors that interact and contribute to the global spread and persistence of dengue in modern societies and the results obtained may yield new understanding of epidemic spreading and the corresponding immunization strategies in dual communities.
FOLIA POMERANAE UNIVERSITATIS TECHNOLOGIAE STETINENSIS

Dioxins represent a group of compounds that are toxic to both humans and animals. Due to their enormous persistence, dioxins accumulate in the environment and organisms on each level of the food chain. For the sake of public health safety, all necessary measures should be taken in order to reduce the emission of dioxins to the environment. Laboratories should examine food for the presence of these substances and legal regulations on food safety standards should be introduced in terms of their tolerable concentrations in food products and animal feed. The aim of the study was to present the current state of knowledge on the toxicity of dioxins, how they threat human and animal health, what preventive measures and regulations are at place to protect consumers against products contaminated with dioxins.
Effect of Controlled Drainage on Loss of Nitrogen and Phosphorous from Paddy Field

Surface drainage is a very important way that nitrogen(N) and phosphorous(P) lost from paddy field. Splash erosion and loss of topsoil from slope and bottom of farm furrows resulted in the loss of N and P. Controlled Drainage could reduced the amount of surface drainage and concentration of N and P in runoff, especially concentration of N and P in runoff, caused the reduction of loss of N and P from paddy field. Deposition of soil grains, decline of concentration of particulate N and P in water absorption by plants as well as nitrification and denitrification were the major reasons for the reduction of N and P in water both in filed and furrows. Controlled drainage could be conducted by controlling drainage time from field and furrow, increasing elevation of spillway, decreasing hydraulic slope of runoff and sediment-carrying capacity. Issues need to be further investigated were also suggested in the end.
THE FIRST OPERATION OF THE HEAVY ION BEAM PROBING DIAGNOSTIC ( HIBP ) ON THE URAGAN-2 M TORSATRON

The Heavy Ion Beam Probing (HIBP) diagnostic system has been installed and operates now on the Uragan-2M torsatron for the first time in Ukraine. The cesium ion beam with energy range of 17.120 keV and ion current of 10.150 μA was used in the first experiments for tracing the probing beam through torsatron magnetic field (0.39.0.4 T). The secondary ion beam with intensity in the range of 30.100 nA was detected on the first deflecting plate of the secondary beam-line according to preliminary calculations by using 80 keV primary beam energy and 100 μA of primary ion current. The primary beam with energy range of 17.20 keV (Ibeam≈10 μA) was traced through torsatron magnetic field towards the analyzer detection plates. PACS: 52.70. Nc. INTRODUCTION
Dark Energy Survey year 1 results: Joint analysis of galaxy clustering, galaxy lensing, and CMB lensing two-point functions

Author(s): Abbott, TMC; Abdalla, FB; Alarcon, A; Allam, S; Annis, J; Avila, S; Aylor, K; Banerji, M; Banik, N; Baxter, EJ; Bechtol, K; Becker, MR; Benson, BA; Bernstein, GM; Bertin, E; Bianchini, F; Blazek, J; Bleem, LE; Bridle, SL; Brooks, D; Buckley-Geer, E; Burke, DL; Carlstrom, JE; Rosell, A Carnero; Kind, M Carrasco; Carretero, J; Castander, FJ; Cawthon, R; Chang, C; Chang, CL; Cho, H-M; Choi, A; Chown, R; Crawford, TM; Crites, AT; Crocce, M; Cunha, CE; D'Andrea, CB; da Costa, LN; Davis, C; de Haan, T; DeRose, J; Desai, S; De Vicente, J; Diehl, HT; Dietrich, JP; Dobbs, MA; Dodelson, S; Doel, P; Drlica-Wagner, A; Eifler, TF; Elvin-Poole, J; Everett, WB; Flaugher, B; Fosalba, P; Friedrich, O; Frieman, J; Garcia-Bellido, J; Gatti, M; Gaztanaga, E; George, EM; Gerdes, DW; Giannantonio, T; Gruen, D; Gruendl, RA; Gschwend, J; Gutierrez, G; Halverson, NW; Harrington, NL; Hartley, WG; Holder, GP; Hollowood, DL; Holzapfel, WL; Honscheid, K; Hou, Z; Hoyle, B; Hrubes, JD; Huterer, D; Jain, B; James, DJ; Jarvis, M; Jeltema, T; Johnson, MWG; Johnson, MD; Kent, S | Abstract: We perform a joint analysis of the auto and cross-correlations between three cosmic fields: the galaxy density field, the galaxy weak lensing shear field, and the cosmic microwave background (CMB) weak lensing convergence field. These three fields are measured using roughly 1300 sq. deg. of overlapping optical imaging data from first year observations of the Dark Energy Survey and millimeter-wave observations of the CMB from both the South Pole Telescope Sunyaev-Zel'dovich survey and Planck. We present cosmological constraints from the joint analysis of the two-point correlation functions between galaxy density and galaxy shear with CMB lensing. We test for consistency between these measurements and the DES-only two-point function measurements, finding no evidence for inconsistency in the context of flat $\Lambda$CDM cosmological models. Performing a joint analysis of five of the possible correlation functions between these fields (excluding only the CMB lensing autospectrum) yields $S_{8}\equiv \sigma_8\sqrt{\Omega_{\rm m}/0.3} = 0.782^{+0.019}_{-0.025}$ and $\Omega_{\rm m}=0.260^{+0.029}_{-0.019}$. We test for consistency between these five correlation function measurements and the Planck-only measurement of the CMB lensing autospectrum, again finding no evidence for inconsistency in the context of flat $\Lambda$CDM models. Combining constraints from all six two-point functions yields $S_{8}=0.776^{+0.014}_{-0.021}$ and $\Omega_{\rm m}= 0.271^{+0.022}_{-0.016}$. These results provide a powerful test and confirmation of the results from the first year DES joint-probes analysis.
Environmental Management: Guidelines for Museums and Galleries

Foreword Preface Acknowledgements Part I: The Principles of Museum Environmental Management 1. Managing Resources 2. Objects, People and Space 3. Developing an Environmental Strategy Part II: Managing and Monitoring the Built Environment 4. Weather, Buildings and Environmental Design 5. The Monitoring Programme Part III: Controlling the Display Environment 6. Controlling from the Centre: Building Management and Environmental Conditioning 7. Control where it's Needed: Room-based Environmental Systems 8. On the Spot: Local Control Part IV: Storage and Transportation: Managing Hidden Stresses 9. Out of Sight, Not Out of Mind 10. Transportation: The Moving Environment Datasheet 1: Record form, spot readings of light and ultraviolet radiation Datasheet 2: Record form, spot readings of relative humidiy and temperature Datasheet 3: Summary chart, weekly minimum and maximum RH, temperature and light readings over 12 months Datasheet 4: Lamp characteristics Select Bibliography Sources of Other Information Glossary Index
Historical survey of the introduced Pecan tree in China advances in science and technology

This article was concerned with a literature review of the scientific and technological advances in pecan introduction and acclimatization in China.These advances were discussed in the aspects of resource inventory,adaptability study,superior tree selection,propagation trial,orchard planting trial,pest control,new germplasm importation,flower bud differentiation,variation in the filial generation and observation of biological characteristics.
Management of Chronic Obstructive Pulmonary Disease (COPD) Exacerbations in Hospitalized Patients From Admission to Discharge: A Comprehensive Review of Therapeutic Interventions

Chronic obstructive pulmonary disease (COPD) is a common and debilitating condition that often necessitates hospitalization for exacerbations. Since COPD exacerbations can cause significant morbidity and mortality, managing them is crucial for patient care. Effective management of COPD exacerbations is essential to prevent complications, as COPD exacerbations are associated with increased healthcare costs and decreased quality of life. This review aims to comprehensively discuss the management of COPD exacerbations, covering various pharmacologic and non-pharmacologic strategies. These include inhaled bronchodilators, systemic steroids, antibiotics, invasive and non-invasive ventilation, oxygen therapy, smoking cessation, immunization with pneumococcal vaccine, inhalers at discharge, pulmonary rehabilitation, long-term oxygen therapy (LTOT), ambulatory oxygen therapy, short-burst oxygen therapy, extracorporeal membrane oxygenation (ECMO), lung volume reduction surgery (LVRS), endobronchial procedures, and lung transplant. It is drawn upon various sources, including clinical studies, systemic reviews, and observational studies, to provide a comprehensive overview of current practices and identify areas for future research and innovation in managing COPD exacerbations. Addressing these areas of interest can improve patient outcomes and quality of life.
Management of chronic obstructive pulmonary disease (COPD)

SYNOPSIS The expiratory airflow obstruction that characterises chronic obstructive pulmonary disease is usually progressive over time and caused by emphysema, obliterative bronchiolitis, and mucus hypersecretion. Stopping smoking is the only measure that slows the progression of chronic obstructive pulmonary disease, and smokers should be encouraged to stop at all stages of the disease. The effects of medication are limited, and need to be balanced against cost and adverse effects. Bronchodilators, given by puffer and spacer rather than by nebuliser, are effective. Avoid inhaled corticosteroids unless there is associated asthma. Pulmonary rehabilitation leads to important improvements in quality of life. Influenza vaccination is helpful. Comorbidity from cardiac disease and sleep disordered breathing are common and can be effectively treated. New therapies under evaluation include lung volume reduction surgery, non-invasive ventilation, and anti-inflammatory drugs.
Chronic active Epstein-Barr virus infection as the basis of neoplasm development. Transformation of chronic lymphocytic leukaemia to NK-cell lymphoma/leukaemia was observed by flow cytometry – a diagnostic report

The case report presents a patient with chronic lymphocytic leukaemia that was diagnosed in 2006 in Rotterdam, the Netherlands. In September 2010, the patient was admitted to the Department of Haematology in Poland due to progression of the underlying disease. The clinical problem during treatment was the suspicion of Richter’s transformation into another, more aggressive non-Hodgkin lymphoma. The diagnosis was based on the peripheral blood immunophenotype. The patient was diagnosed with an immunoglobulin deficiency. Unfortunately, repeated examinations did not confirm the transformation hypothesis, despite the increasing symptoms. The patient was treated with various therapeutic regimens until May 2021, when an increased number of NK cells was diagnosed in the peripheral blood. NK-cell lymphoproliferative disease was finally diagnosed de novo. Nevertheless, it was found that the patient had active Epstein-Barr virus (EBV) and Cytomegalovirus (CMV) infection. The suspected NK-cell lymphoma/leukaemia was most likely a complication of the active EBV infection and severe immunodeficiency state.
Utilisation des charges maximales et cumulatives sur la colonne vertébrale pour évaluer les emplois, la rotation des emplois et les contrôles techniques

Il a ete demontre que les forces maximales et cumulatives exercees sur les structures de la colonne vertebrale constituent des facteurs de risques significatifs et statistiquement independants pour la declaration de douleurs au dos. Le present document decrit une approche logicielle qui utilise ces facteurs de risques pour predire de facon quantitative la declaration de douleurs au dos a l’aide d’un pointage des indices de declaration de douleur au dos, ou pointage IDDD. On a evalue deux emplois dans le secteur de la fabrication automobile avec cette approche, puis on a elabore au moyen des resultats obtenus un controle specifique de nature administrative et technique. En analysant les emplois avec les controles en place, on a constate que le controle administratif utilise, soit la rotation des emplois, etait moins efficace que prevu et engendrait une augmentation globale du risque de declaration de douleur au dos. La mise en place d’un controle technique a fait diminuer globalement le risque de declaration de douleur au dos, et ce, pour tout travailleur occupant le poste en question. Les resultats de cette etude indiquent qu’il faut considerer a la fois les charges maximales et les charges cumulatives afin d’evaluer adequatement le risque de blessures et les consequences associees a la mise en place de controles techniques et administratifs.
La Relación Virtuosa De La Seguridad Y La Inversión Extranjera Directa En Colombia (1994-2013) (The Virtuous Relationship of Security and Foreign Direct Investment in Colombia (1994-2013))

Spanish Abstract: Este articulo considera el PIB, la inversion extranjera directa y el crimen en Colombia, entre 1994 y 2013, para explorar relaciones que se pueden presentar entre ellas, teniendo en cuenta un indice de criminalidad, que agrupa delitos de alto impacto. La hipotesis es que las mejores condiciones de seguridad en el pais durante la decada anterior, que se evidencia con la reduccion del indice de criminalidad, favorecieron el incremento en la inversion extranjera, lo que posibilita finalmente un mayor desarrollo economico y social en el largo plazo. Para contrastar la hipotesis, se utiliza un modelo ARIMA-ARCH que recoge la volatilidad y la inercia de las variables, encontrando una relacion inversa entre el crimen y la inversion extranjera; una relacion directa entre la inversion extranjera y el producto; y una relacion inversa entre el indicador de crimen y el producto del pais.English Abstract: This article considers GDP, foreign direct investment and crime in Colombia, between 1994 and 2013, in order to explore the relations that can exist between them, taking into consideration a Criminality Index, which brings together high impact crimes. The hypothesis states that better security conditions in the country during the previous decade, evidenced by the reduction of the criminality index, favored the increase of foreign investment, which ultimately enables a greater economic and social development in the long run. To test the hypothesis, an ARIMA-ARCH model is used, which takes up the volatility and inertia of the variables, finding an inverse relationship between crime and foreign investment; a direct relationship between foreign investment and product; and an inverse relationship between crime index and the country’s product.
Academic Achievement in America's Small Schools: Data from High School and Beyond.

This paper examines differences in educational outcomes among 1,792 students from small (fewer than 300 pupils), average (400-700 pupils), and large (900-1,200 pupils) rural high schools, and among 1,084 students from small high schools in urban, suburban, and rural settings. Data were drawn from the High School and Beyond database, a national sample of high school students surveyed four times from 1980-86. In the rural schools, socioeconomic status (SES) explained between 10-20% of the variability in all of the dependent measures except two; gender explained as much variance in the writing measure as SES; and school size was nct significantly related to any dependent variable. Once socioeconomic status was urbanicity produced only negligible differences in ecademic outcomes. School size produced nonsignificant but consistent differences in educational outcomes. In all cases except the mathematics measure, students from small schools had higher mean scores on the dependent measures than other students, and students from moderately sizt' schools had higher mean scores than those from large schools. This report contains 15 references and 6 data tables.
Community-Acquired Pneumonia in Children

Abstract Community-acquired pneumonia (CAP) is the most common cause of childhood mortality globally. In the United States, CAP is a leading cause of pediatric hospitalization and antibiotic use and is associated with substantial morbidity. There has been a dramatic shift in microbiological etiologies for CAP in children over time as pneumococcal pneumonia has become less common and viral etiologies have become predominant. There is no commonly agreed on approach to the diagnosis of CAP in children. When indicated, antimicrobial treatment should consist of narrow-spectrum antibiotics. In this article, we will describe the current understanding of the microbiological etiologies, clinical presentation, diagnostic approach, risk factors, treatment, and future directions in the diagnosis and management of pediatric CAP.