Miracle-dz/UniFAR-FTUs huggingface dataset:
LATIHAN FISIK BELUM MAMPU MEMPERBAIKI GAMBARAN HISTOLOGIS PARU MENCIT (Mus Musculus) JANTAN GALUR BALB/C YANG DIPAPAR UAP ROKOK ELEKTRIK

Saat ini rokok elektrik diduga kuat memiliki kandungan bahan yang berbahaya bagi kesehatan manusia. Salah satu upaya untuk untuk mempertahankan kesehatan paru akibat paparan uap rokok elektrik yaitu perlu dilakukan latihan fisik teratur intensitas sedang. Latihan fisik diharapkan mampu memberikan efek perbaikan histologis alveolus paru setelah paparan uap rokok elektrik. Penelitian ini merupakan penelitian eksperimental laboratorik post-test only group design. Sampel penelitian terdiri dari 27 ekor mencit (Mus Musculus) jantan Galur BALB/C yang berusia 2-3 bulan dengan berat badan 25-35 gram. Sampel dibagi menjadi 3 kelompok secara acak yaitu (K1) kontrol normal, (K2) kontrol negatif yang diberikan paparan uap rokok elektrik, dan (K3) kelompok perlakuan yang diberikan paparan uap rokok elektrik dengan perlakuan latihan fisik aerobik intensitas sedang. Hasil penelitian menunjukkan bahwa latihan fisik belum mampu memperbaiki gambaran histologis alveolus paru (p>0,05) yang diberikan paparan uap rokok eleketrik pada mencit jantan galur BALB/C. Kata Kunci: Latihan Fisik; Rokok Elektrik; Histologis Alveolus.
Structural Characteristics, Antioxidant, and Immunostimulatory Activities of an Acidic Polysaccharide from Raspberry Pulp

The extraction and characterization of new bioactive plant-derived polysaccharides with the potential for use as functional foods and medicine have attracted much attention. In the present study, A novel acidic polysaccharide (RPP-3a) with a weight-average molecular weight (Mw) of 88,997 Da was isolated from the raspberry pulp. RPP-3a was composed of rhamnose, arabinose, galactose, glucose, mannose, and galacturonic acid at a molar ratio of 13.1:28.6:16.8:1.4:6.2:33.9. Structural analysis suggested that the RPP-3a backbone was composed of repeating units of →4)-β-Galp-(1→3,4)-α-Rhap-(1→[4)-α-GalAp-(1→4)-α-GalAp-(1→]n with branches at the C-4 position of rhamnose. The side chain of RPP-3a, containing two branch levels, was comprised of α-Araf-(1→, →5)-α-Araf-(1→, →3,5)-α-Araf-(1→, →3)-β-Galp-(1→, →3,6)-β-Galp-(1→, →4)-β-Glcp-(1→, and →2,6)-α-Manp-1→ residues. RPP-3a exhibited moderate reducing power and strong hydroxyl and superoxide anion radical scavenging abilities. RPP-3a significantly promoted the viability of RAW264.7 macrophages by increasing the production of nitric oxide (NO), tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), and interleukin-1β (IL-1β) at both the expression and transcriptional levels. In summary, the immunostimulatory and antioxidant activities make RPP-3a a viable candidate as a health-beneficial functional dietary supplement.
Clinical Characteristics and Potential Pathogenesis of Cardiac Necrotizing Enterocolitis in Neonates with Congenital Heart Disease: A Narrative Review

Neonates with congenital heart disease (CHD) are at an increased risk of developing necrotizing enterocolitis (NEC), an acute inflammatory intestinal injury most commonly associated with preterm infants. The rarity of this complex disease, termed cardiac NEC, has resulted in a dearth of information on its pathophysiology. However, a higher incidence in term infants, effects on more distal regions of the intestine, and potentially a differential immune response may distinguish cardiac NEC as a distinct condition from the more common preterm, classical NEC. In this review, risk factors, differentiated from those of classical NEC, are discussed according to their potential contribution to the disease process, and a general pathogenesis is postulated for cardiac NEC. Additionally, biomarkers specific to cardiac NEC, clinical outcomes, and strategies for achieving enteral feeds are discussed. Working towards an understanding of the mechanisms underlying cardiac NEC may aid in future diagnosis of the condition and provide potential therapeutic targets.
Post‐yield deformation parameters of reinforced concrete beam with corroded reinforcement

This paper represents the post‐yield behavior of reinforced concrete (RC) beams with corroded reinforcement. In order to assess the seismic suitability of existing structures, effect of corrosion in reinforcement on the behavior of various structural elements should be studied. Strong column weak beam behavior should occur in seismically efficient structure which ensures maximum plastic hinges to form in the beams. Plastic hinge parameters in RC beams should be clearly identified for repair and retrofitting of the old buildings and seismic analysis of new buildings too. As the concept of plastic hinges are extremely important in seismic analysis of existing RC structures which defines the deformation and load‐carrying capacities of the RC beam. Sixteen simply supported beam types (three samples of each type) are tested with varying grade of concrete and type of reinforcement along with the condition of reinforcement (10, 20, and 30% corroded reinforcement) by applying two point loading (approximately one‐third and two‐third of span). Test results show that the RC beams with bars corroded to 30% have undesirable shear failure though have been designed to fail in flexure. The plastic hinge length (denoted as lp) increases with the increase in concrete grade and decreases with the increase in yield strength of reinforcement. The increase in the corrosion percentage of reinforcement bars from 10 to 30% decreases the plastic hinge length, making it undesirable as a seismic member.
Analysis and Comparison of Different Approaches to Implementing a Network-Based Parallel Data Processing Algorithm

It is well known that network-based parallel data processing algorithms are well suited to implementation in reconfigurable hardware recurring to either Field-Programmable Gate Arrays (FPGA) or Programmable Systems-on-Chip (PSoC). The intrinsic parallelism of these devices makes it possible to execute several data-independent network operations in parallel. However, the approaches to designing the respective systems vary significantly with the experience and background of the engineer in charge. In this paper, we analyze and compare the pros and cons of using an embedded processor, high-level synthesis methods, and register-transfer low-level design in terms of design effort, performance, and power consumption for implementing a parallel algorithm to find the two smallest values in a dataset. This problem is easy to formulate, has a number of practical applications (for instance, in low-density parity check decoders), and is very well suited to parallel implementation based on comparator networks.
Methanol biotransformation toward high-level production of fatty acid derivatives by engineering the industrial yeast Pichia pastoris

Significance Methanol-based biomanufacturing is considered a promising way to achieve carbon neutrality. However, efficient methanol biotransformation toward chemical production is challenging. To address this challenge, we enhanced the precursor supply and coenzyme regeneration in Pichia pastoris, combined with reinforcing methanol assimilation, which resulted in significant improvements in fatty acid production. Furthermore, we offered an effective approach for rapidly constructing versatile cell factories that share common precursors. This study represents an important step forward in the rewiring of P. pastoris as industrial microbial cell factories for chemical production.
Initial designs of wheelchair rugby gloves

Wheelchair rugby is a sport played by approximately 200 people in the United Kingdom. Despite being a small part of the population, research suggests that there are some aspects related to the sports-wear that need attention. This is especially relevant for gloves, as they have been identified as one of the main causes of performance losses. Until now, there are no gloves available on the market that were developed to respond to this sport’s needs and requirements. The purpose of this paper was to present the concepts of the initial designs and first prototype of a pair of gloves created for wheelchair rugby. The designs were developed based on the feedback from one UK-based wheelchair rugby team. Of the designs produced only one was selected to be developed as a physical prototype. This particular design had in consideration the most important features identified by the athletes, namely the easiness of putting on and taking off the gloves, the padding and grip in specific areas and the elimination of the need for tape to secure.
Adaptive transmission for radar arrays using Weiss–Weinstein bounds

We present an algorithm for adaptive selection of pulse repetition frequency or antenna activations for Doppler and DoA estimation. The adaptation is performed sequentially using a Bayesian filter, responsible for updating the belief on parameters, and a controller, responsible for selecting transmission variables for the next measurement by optimizing a prediction of the estimation error. This selection optimizes the Weiss-Weinstein bound for a multi-dimensional frequency estimation model based on array measurements of a narrow-band far-field source. A particle filter implements the update of the posterior distribution after each new measurement is taken, and this posterior is further approximated by a Gaussian or a uniform distribution for which computationally fast expressions of the Weiss-Weinstein bound are analytically derived. We characterize the controller's optimal choices in terms of SNR and variance of the current belief, discussing their properties in terms of the ambiguity function and comparing them with optimal choices of other Weiss-Weinstein bound constructions in the literature. The resulting algorithms are analyzed in simulations where we showcase a practically feasible real-time evaluation based on look-up tables or small neural networks trained off-line.
Decentralization of Virtual Linkage in Formation Control of Multi-Agents via Consensus Strategies

Featured Application: This paper addresses the formation control of a team of agents based on the decentralized control and the recently introduced reconfigurable virtual linkage approach. Following a decentralized control architecture, a decentralized virtual linkage approach is introduced. As compared to the original virtual linkage approach, the proposed approach uses decentralized architecture rather than hierarchical architecture, which does not require role assignments in each virtual link. In addition, each agent can completely decide its movement with only exchanging states with part of the team members, which makes this approach more suitable for situations when a large number of agents and/or limited communication are involved. Furthermore, the reconfiguration ability is enhanced in this approach by introducing the scale factor of each virtual link. Finally, the effectiveness of the proposed method is demonstrated through simulation results.
Association between urinary concentrations of bisphenol A substitutes and diabetes in adults

BACKGROUND Due to new restrictions on the use of bisphenol A (BPA), industries are beginning to replace it with derived molecules such as bisphenol S and F (BPS and BPF). There is extensive evidence in the academic literature on the potential health effects of BPA, which is known to be a diabetogenic molecule. However, there are few publications related to new compounds derived from BPA. AIM To perform an epidemiological study of urinary BPS and BPF in the American National Health and Nutrition Examination Survey (NHANES) cohort, and analyze their possible relationship with diabetes mellitus. METHODS NHANES datasets from 2013 to 2016 were used due to the urinary BPF and BPS availability. Data from 3658 adults were analyzed to perform regression analysis exploring the possible relationship between BPA-derived compounds and diabetes. RESULTS Descriptive statistics, linear regression modeling, and logistic regression analysis revealed a significant relationship between urinary BPS, but not BPF, and diabetes risk. Additionally, a relationship was observed between both compounds and hypertension and a slight relationship between BPF and dyslipidemia. CONCLUSION In the present study, a strong relationship between urinary BPS, not BPF, and diabetes risk has been determined. BPA substitute molecules do not exempt the population from potential health risks.
A Comparative Study of Compressive Sensing Algorithms for Hyperspectral Imaging Reconstruction

Hyperspectral Imaging comprises excessive data consequently leading to significant challenges for data processing, storage and transmission. Compressive Sensing has been used in the field of Hyperspectral Imaging as a technique to compress the large amount of data. This work addresses the recovery of hyperspectral images $ 2.5\times$ compressed. A comparative study in terms of the accuracy and the performance of the convex FISTA/ADMM in addition to the greedy gOMP/BIHT/CoSaMP recovery algorithms is presented. The results indicate that the algorithms recover successfully the compressed data, yet the gOMP algorithm achieves superior accuracy and faster recovery in comparison to the other algorithms at the expense of high dependence on unknown sparsity level of the data to recover.
Separate removal of random noise and clutter in GPR images based on Self2Self and NSST

ABSTRACT Hyper-wavelet transforms such as the non-subsampled shearlet transform (NSST) are popular algorithms to remove random noise and clutter in ground penetrating radar (GPR) images. However, due to the effect of time-varying gain, random noise and clutter in GPR images are non-stationary. Moreover, random noise which is poorly correlated among pixels and clutter which shows a certain correlation among adjacent pixels are usually mixed together. Therefore, it is difficult to determine the threshold function of hyper-wavelet transforms, resulting in a decrease of noise and clutter removal performance. To address this issue, a novel two-step algorithm is proposed to remove non-stationary random noise and clutter in the GPR image separately. In the first step, Self2Self, a self-supervised denoising algorithm, is employed to remove the non-stationary random noise. In the second step, a time-varying threshold function based on NSST and an edge area protection method based on the Canny algorithm are proposed to effectively remove non-stationary clutter in the GPR image. Experimental results show that the proposed method has an excellent performance in removing non-stationary random noise and clutter while effectively protecting the edge information of the GPR image.
IMMOBILIZED ARTIFICIAL MEMBRANE CHROMATOGRAPHY: A USEFUL TOOL FOR PREDICTING MEMBRANE PERMEABILITY

The potential of immobilized artificial membrane chromatography (IAM) chromatography to predict intestinal and blood brain barrier (BBB) permeability was investigated utilizing retention indices and other permeability factors compiled from literatures such as the lipophilicity factor, logarithms of octanol/water partition coefficient (log P) and blood/brain partition coefficient (log BB). For this purpose, the separation of a diverse structures and functions set of 21 compounds was studied on stationary immobilized artificial membrane chromatography and their chromatographic retention factors; namely aqueous capacity factor (log K IAMW ) were determined. The aqueous capacity factors of the compounds were correlated with their log P and log BB. Linear correlation was obtained between log K IAMW and log P of the compounds (r > 0.95). Log K IAMW values of the compounds also showed an acceptable correlation with log BB (r > 0.76). Inclusion of the molecular size of the compounds with log K IAMW data had negative effect on correlations when the data plotted vs. log BB values. For a subset of 8 compounds, log K IAMW showed better correlation with log % of human absorption than did log P. These results show that the aqueous capacity factor, log K IAMW seems to provide a valuable assessment of drug permeability through biological membranes.
ICEBERG : a different look at software project management

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Active Power Filter Control With Vibrating Coordinates Transformation

This paper presents a control system of an active power filter (APF) based on vibrating reference frame transformation. The proposed vibrating reference frame provides a representation of non-sinusoidal quantities (here the active filter current vector) in the form of sinusoidal signals in a stationary frame, and thanks to that, DC signals are achieved in a dq synchronously rotating frame. The article presents theoretical analysis as well as simulation and experimental tests.
A Novel Coding Based Dimming Scheme with Constant Transmission Efficiency in VLC Systems

Visible light communication (VLC) has attracted tremendous attention due to two functions: communication and illumination. Both reliable data transmission and lighting quality need to be considered when the transmitted signal is designed. To achieve the desired levels of illumination, dimming control is an essential technology applied in VLC systems. In this paper, we propose a block coding-based dimming scheme to construct the codeword set, where dimming control can be achieved by changing the ratio of two levels (ON and OFF) based on on-off keying (OOK) modulation. Simulation results show that the proposed scheme can maintain good error performance with constant transmission efficiency under various dimming levels.
RHMD: A Real-World Dataset for Health Mention Classification on Reddit

People on social media share their thoughts and experiences using diseases and symptoms words other than to mention their health, which can introduce biases in data-driven public health applications. For the advancement of HMC research, in this study, we present a Reddit health mention dataset (RHMD), a new dataset of multi-domain Reddit data for the HMC. RHMD is composed of 10015 manually annotated Reddit posts that include 15 common disease or symptom terms and are labeled with four labels: personal health mentions (HMs), nonpersonal HMs, figurative HMs, and hyperbolic HMs. Empirical evaluation using recently proposed methods demonstrates the challenge of labeling user-generated text across these four types. Contributions to this work include the public release of a robustly annotated Reddit dataset (RHMD) for HM tasks and a comprehensive performance analysis of baseline methods. We expect the release of the dataset, and the evaluations will help facilitate the development of new methods for detecting HMs in the user-generated text. The dataset is available at https://github.com/usmaann/RHMD-Health-Mention-Dataset.
Supported Gold Nanoparticle-Catalyzed Selective Reduction of Multifunctional, Aromatic Nitro Precursors into Amines and Synthesis of 3,4-Dihydroquinoxalin-2-Ones

The synthesis of 3,4-dihydroquinoxalin-2-ones via the selective reduction of aromatic, multifunctional nitro precursors catalyzed by supported gold nanoparticles is reported. The reaction proceeds through the in situ formation of the corresponding amines under heterogeneous transfer hydrogenation of the initial nitro compounds catalyzed by the commercially available Au/TiO2-Et3SiH catalytic system, followed by an intramolecular C-N transamidation upon treatment with silica acting as a mild acid. Under the present conditions, the Au/TiO2-TMDS system was also found to catalyze efficiently the present selective reduction process. Both transfer hydrogenation processes showed very good functional-group tolerance and were successfully applied to access more structurally demanding products bearing other reducible moieties such as chloro, aldehyde or methyl ketone. An easily scalable (up to 1 mmol), low catalyst loading (0.6 mol%) synthetic protocol was realized, providing access to this important scaffold. Under these mild catalytic conditions, the desired products were isolated in good to high yields and with a TON of 130. A library analysis was also performed to demonstrate the usefulness of our synthetic strategy and the physicochemical profile of the derivatives.
Design of wide band printed monopole antenna for low rate wireless personal area networks

A dual‐band printed monopole antenna useful in low‐rate wireless personal area networks (LR‐PAN) and GPS operation for tablet devices is presented. Antenna has monopole strips arranged in planar configuration on substrate suitable to match standard tablet computer display size. The overall antenna dimension is 150 × 50 × 1.6 mm3. The long and short strips of monopole are separated by notch to increase the bandwidth of antenna. The operating impedance bandwidths of 14.97% and 5.09% are obtained across LR‐PAN band and GPS band, respectively. The presented monopole antenna provides significant gain in order of 4.48 dBi for lower resonant mode and 3.26 dBi for higher resonant mode. The antenna covers LR‐WPAN frequency bands of 868.3 MHz, 915/920 MHz, GSM 850, UMTS/LTE 850, 1.57 GHz GPS bands.
Robust ranking by ensembling of diverse models and assessment metrics

We propose an ensemble of classification models formed using different assessment metrics. For a given metric, a classifier performs feature selection and combines models based on different subsets of feature variables which we call phalanxes. This first step, which employs the algorithm of phalanx formation, identifies strong and diverse subsets of feature variables. A second phase of ensembling aggregates classifiers across diverse assessment metrics. The proposed method is applied to protein homology data to mine homologous proteins, where the feature variables used for developing classifiers are various measures of similarity scores of proteins, and found robust for ranking both evolutionary close and distant homologous proteins.
Performance feedback and strategic R&D classification: a further study of R&D tax credit

ABSTRACT Tax incentives are an important measure in most industrial countries to support firms R&D. However, R&D tax credit leads firms to engage in strategic R&D classification that classifies indirect costs as eligible R&D inputs in order to reduce tax liability. Based on the behavioural theory of the firm, we investigate the impact of performance feedback on firm’s strategic R&D classification. The results show that when performance falls below aspirations, the pressure to achieve aspirations forces firms to reduce strategic R&D classification; when performance is above aspirations, in order to reduce tax liabilities, firms are more willing to engage in strategic R&D classification due to the lack of performance pressure. Our study helps to understand horizontal differences in R&D investment in the context of tax incentives.