Miracle-dz/UniFAR-FTUs huggingface dataset:
Yellow Fever Vaccine-Related Neurotropic Disease in Brazil Following Immunization with 17DD

The disease burden of yellow fever virus infection (YFV) is quite high in the tropics where vaccination coverage is low. To date, vaccination is the most effective control strategy to mitigate and eliminate the burden of YF disease. The licensed YF vaccines are safe and effective and serious adverse events are rare. Herein, we report three cases of neurological syndrome, compatible with meningoencephalitis following 17DD vaccination. In all cases, YFV-specific IgM antibodies were detected in the cerebrospinal fluid. Our observations confirm the development of YF vaccine-associated neurotropic disease, a rare serious adverse event, from which all three patients have fully recovered without any long-term sequelae. This report reinforces the need for awareness among health professionals to recognize and effectively manage such events in a timely manner.
Home-Based Primary Care for Older Adults: Matched Case-Control Evaluation of Program’s Impact on Healthcare Utilization

Home-based Primary Care (HBPC) is an alternative model for homebound older adults. Healthcare utilization in HBPC was evaluated with a matched case-control design. Medical providers and social workers provided in-home visits. Enrolled patients were matched to controls on age, prior hospitalizations, and frailty risk. Difference-in-differences in utilization of primary care, specialty, and hospital services between 1-year pre- and 1-year post-enrollment were evaluated with hierarchical linear models. Analyses included 117 HBPC cases and 328 controls. HBPC cases had a significant increase in primary care visits compared to controls (7.8 ± 0.6; p < .0001) but significantly decreased utilization of in-clinic primary care visits (−3.2 ± 0.6; p < .0001). In-clinic specialty visits and hospital services did not differ between cases and controls (all p’s ≥ .75). Homebound patients accessed high-touch primary and social care, which is typically unachievable in clinic settings; however, additional work is needed to optimize services and target in-home care to impact healthcare utilization.
Improved guaranteed computable bounds on homogenized properties of periodic media by the Fourier–Galerkin method with exact integration

Moulinec and Suquet introduced FFT‐based homogenization in 1994, and 20years later, their approach is still effective for evaluating the homogenized properties arising from the periodic cell problem. This paper builds on the author's (2013) variational reformulation approximated by trigonometric polynomials establishing two numerical schemes: Galerkin approximation (Ga) and a version with numerical integration (GaNi). The latter approach, fully equivalent to the original Moulinec–Suquet algorithm, was used to evaluate guaranteed upper–lower bounds on homogenized coefficients incorporating a closed‐form double‐grid quadrature. Here, these concepts, based on the primal and dual formulations, are employed for the Ga scheme. For the same computational effort, the Ga outperforms the GaNi with more accurate guaranteed bounds and more predictable numerical behaviors. The quadrature technique leading to block‐sparse linear systems is extended here to materials defined via high‐resolution images in a way that allows for effective treatment using the FFT. Memory demands are reduced by a reformulation of the double‐grid scheme to the original grid scheme using FFT shifts. Minimization of the bounds during iterations of conjugate gradients is effective, particularly when incorporating a solution from a coarser grid. The methodology presented here for the scalar linear elliptic problem could be extended to more complex frameworks. Copyright © 2015 John Wiley & Sons, Ltd.
Atomistic simulations on the mechanical properties of silicene nanoribbons under uniaxial tension

The mechanical properties of silicene are investigated using ab initio calculation and molecular dynamics simulations with different empirical potentials. The simulation results show that the calculated Young's modulus of bulk silicene with EDIP model is consistent with the ab initio calculations. The chirality has a significant effect on the critical strain and stress of bulk silicene under uniaxial tension. In addition, the Young's modulus depends strongly on the chirality and size of the silicene nanoribbon due to the edge effects. The fracture process of a silicene nanoribbon is also studied.
Algebraic condition for observability of non-linear analytic systems

Abstract The observability of non-linear analytic systems can be assessed by means of Kalman's rank condition, when the system is represented in terms of the evolution equations of an associated infinite family of tensor powers of the state vector. Carleman's exact linearization provides the necessary link to transform differential-geometric observability conditions into Kalman's algebraic rank condition.
Effect of Polarization Fatigue on Harvesting Energy Using Pyroelectric Materials

The phenomenon of polarization fatigue in ferroelectric materials is defined and the effect of this phenomenon on harvested energy using these materials has been studied. In order to illustrate this effect, the harvested energy using PZN-4.5PT single crystal was compared in two cases of fatigued and nonfatigued samples. The results have been calculated between two temperatures of 100 and 130°C using Ericsson thermodynamic cycle.
Enhanced snow and ice identification with the VIIRS cloud mask algorithm

New procedures have been developed to help identify snow and sea ice with the Suomi-National Polar-orbiting Partnership (S-NPP) Visible Infrared Imager Radiometer Suite (VIIRS) Cloud Mask (VCM) algorithm. The accurate detection of snow and sea ice is necessary in order to apply the correct spectral tests needed to detect clouds and make accurate cloud confidence classifications. During the VCM Calibration Validation activity, it was found that the procedures in place at the time of the satellite launch occasionally produced four types of misclassifications: (1) snow and/or ice surfaces in dry atmospheric regions misclassified as clouds, (2) multi-layered clouds in humid regions misclassified as snow, (3) low-level clouds with glaciated tops misclassified as sea ice, and (4) frozen lakes not classified as ice. The new procedures presented in this article use data collected in the VIIRS mid-wavelength region, i.e. both the 3.7 μm and 4.0 μm bands, as well as the 12.0 μm IR band to eliminate all four types of misclassifications. The results demonstrate that split window, mid-wavelength IR imagery provides valuable information for developers of automated cloud classification algorithms as well as those who generate sea ice analyses in support of ocean navigation during polar wintertime conditions. It is concluded that collecting data in these mid-wavelength IR bands should be considered part of any future satellite sensor designed for environmental monitoring.
New specimens of the early Permian apex predator Varanops brevirostris at Richards Spur, Oklahoma, with histological information about its growth pattern

An articulated pelvic region and additional isolated material of Varanops brevirostris, which are indistinguishable from those of the generotype from the Cacops bonebed, demonstrate the presence of this large varanopid at the Richards Spur locality. The articulated specimen includes lumbar, sacral, and anterior caudal vertebrae, partial pelvis, femur, and proximal part of tibia, confirming the autapomorphies previously suggested for this species. These include the presence of distinct blade-like shapes of the neural spines in the sacral region, the presence of deeply excavated pubis, and the presence of a distinct transverse ridge on the ventral surface of the femur distal to the intertrochanteric fossa. It has also been found that the transverse ridges and grooves become larger during ontogeny since the juvenile specimen did not exhibit a well-developed ridge. Histological analysis of isolated limb bones and neutron computed tomography (nCT) of the articulated specimen indicate that the latter likely belonged to an adult individual. This is in contrast to the other varanopid at Richards Spur, the significantly smaller, more gracile predator Mesenosaurus efremovi, which also shows the presence of growth lines and the external fundamental system with an estimated minimum age of fourteen.
Complement 1q/Tumor Necrosis Factor-Related Proteins (CTRPs): Structure, Receptors and Signaling

Adiponectin and the other 15 members of the complement 1q (C1q)/tumor necrosis factor (TNF)-related protein (CTRP) family are secreted proteins composed of an N-terminal variable domain followed by a stalk region and a characteristic C-terminal trimerizing globular C1q (gC1q) domain originally identified in the subunits of the complement protein C1q. We performed a basic PubMed literature search for articles mentioning the various CTRPs or their receptors in the abstract or title. In this narrative review, we briefly summarize the biology of CTRPs and focus then on the structure, receptors and major signaling pathways of CTRPs. Analyses of CTRP knockout mice and CTRP transgenic mice gave overwhelming evidence for the relevance of the anti-inflammatory and insulin-sensitizing effects of CTRPs in autoimmune diseases, obesity, atherosclerosis and cardiac dysfunction. CTRPs form homo- and heterotypic trimers and oligomers which can have different activities. The receptors of some CTRPs are unknown and some receptors are redundantly targeted by several CTRPs. The way in which CTRPs activate their receptors to trigger downstream signaling pathways is largely unknown. CTRPs and their receptors are considered as promising therapeutic targets but their translational usage is still hampered by the limited knowledge of CTRP redundancy and CTRP signal transduction.
A note on vortex streets behind circular cylinders at low Reynolds numbers

A discussion is given of the current state of knowledge of vortex streets behind circular cylinders in the Reynolds number range 50 to 160. This was prompted by Gaster's (1969) report that he could not find the transition at a Reynolds number of about 90 observed by Tritton (1959) and Berger (1964a). A further brief experiment confirming the existence of the transition is described Reasons for rejecting Gaster's interpretation are advanced. Possible (mutually alternative) explanations of the discrepant observations are suggested.
Guillain-Barre syndrome following COVID-19 vaccines: A review of literature

Objective This study aimed to retrospectively analyze reported Guillain–Barré syndrome (GBS) cases that occurred after COVID-19 vaccination. Methods Case reports of GBS following COVID-19 vaccination that were published before May 14, 2022, were retrieved from PubMed. The cases were retrospectively analyzed for their basic characteristics, vaccine types, the number of vaccination doses before onset, clinical manifestations, laboratory test results, neurophysiological examination results, treatment, and prognosis. Results Retrospective analysis of 60 case reports revealed that post-COVID-19 vaccination GBS occurred mostly after the first dose of the vaccination (54 cases, 90%) and was common for DNA vaccination (38 cases, 63%), common in middle-aged and elderly people (mean age: 54.5 years), and also common in men (36 cases, 60%). The mean time from vaccination to onset was 12.3 days. The classical GBS (31 cases, 52%) was the major clinical classification and the AIDP subtype (37 cases, 71%) was the major neurophysiological subtype, but the positive rate of anti-ganglioside antibodies was low (7 cases, 20%). Bilateral facial nerve palsy (76% vs 18%) and facial palsy with distal paresthesia (38% vs 5%) were more common for DNA vaccination than for RNA vaccination. Conclusion After reviewing the literature, we proposed a possible association between the risk of GBS and the first dose of the COVID-19 vaccines, especially DNA vaccines. The higher rate of facial involvement and a lower positive rate of anti-ganglioside antibodies may be a characteristic feature of GBS following COVID-19 vaccination. The causal relationship between GBS and COVID-19 vaccination remains speculative, more research is needed to establish an association between GBS and COVID-19 vaccination. We recommend surveillance for GBS following vaccination, because it is important in determining the true incidence of GBS following COVID-19 vaccination, as well as in the development of a more safer vaccine.
A Timestepping Scheme for Coupled Reservoir Flow and Geomechanics on Nonmatching Grids

This paper presents numerical techniques for coupled simulations with different time scales and space discretizations for reservoir flow and geomechanics. We use an explicitly coupled approach together with an iterative coupling to increase stability and reduce time discretization error. An error indicator is proposed to determine when displacement must be updated and whether the explicit or iterative coupling technique is required. Under this setting, one geomechanics calculation is performed for several reservoir flow steps. For time steps without geomechanics updates linear extrapolated pore volume is used for porous flow calculations. The resulting algorithm is computationally more efficient than the iterative coupling, and it is more stable and accurate than the loosely coupled technique. In the event that different meshes are used for the reservoir flow and geomechanics models, special treatments are required for the integration of the coupling terms over each element. To avoid complex 3D grid intersection calculations we propose to divide an element into a number of subelements and apply the midpoint integration rule over each subelement. Numerical results are presented to demonstrate the efficiency and accuracy of the proposed method for coupled simulations with different time and space discretizations.
Attosecond neutron scattering from open quantum systems: Entanglement and decoherence phenomena of protons in condensed matter and molecules

In general, nuclei and electrons in condensed matter and/or molecules are entangled, due to the prevailing (electromagnetic) interactions. As a matter of fact, the environment interacting with a microscopic system of interest (e.g. a proton) causes the destruction of the entanglement. This process, called decoherence, has until now prevented experimenters from directly accessing atomic and/or nuclear entanglement effects in real experiments. However, our neutron and electron Compton scattering experiments from protons (H-atoms) in several condensed systems and molecules at ambient conditions demonstrated a new striking effect, i.e. an anomalous decrease of scattering intensity from protons, which seem to become partially invisible to the neutrons. This effect, which has no interpretation within conventional neutron scattering theory, is proposed to be caused by the non-unitary time evolution (due to decoherence) during the ultrashort, but finite, time-window of the neutron-proton scattering process. Due to the large energy (several eV) and momentum (20-200 A−1) transfers of these experiments the collisional time between the probe particle and a struck proton is 100–1000 attoseconds long. It is shown that, due to this short timescale, the scattering process must be theoretically treated within quantum dynamics of open quantum systems. New experimental neutron Compton scattering results from a single crystal KHCO3 are presented. They provide the first direct evidence for a connection between the momentum distribution and the anomalous scattering intensity of H. Additionally, recent experiments with electron-atom Compton scattering at momentum transfers are mentioned, which reveal the presence of this effect even in scattering from single H2 molecules in the gas phase. Theoretical discussions from first principles are presented, also in relation to the quantum Zeno effect, which underline the crucial role of decoherence in the considered experiments. The experimental results and their qualitative interpretation show that epithermal neutrons being available at spallation sources (e.g. ISIS/UK, SNS/USA or ESS/Sweden), and electron spectrometers with large scattering angles, provide tools for investigating new physical and chemical phenomena in the sub-femtosecond timescale.
CHEMICALLY-CONTROLLED REACTION KINETICS ON FRACTALS: APPLICATION TO HYDROGEN EXCHANGE IN LYSOZYME

The effect of time-dependent diffusional rate constants on chemically-controlled reactions in solution is considered. A general mechanism is examined that consists of a two step process. First the reactants diffuse together to form an “encounter complex. ” This is followed by the collapse of the complex to the final product. The first step is diffusion controlled and the second step is chemically controlled. For reactions in restricted geometries or on fractals the rate constants associated with the diffusive process will scale with time as t−h where h is a constant between 0 and 1. The chemical processes are assumed to have time-independent rate constants. For reactions in which the encounter complex achieves a steady state, the differential equations governing the time course of the reaction can be solved exactly. At short times, the concentration of the reactants decays exponentially, reflecting the time constant of the chemical processes. At longer times, the decreasing diffusive rate constants result in the process being diffusion controlled. A stretched exponential of the form, exp{−kt1−h}, is observed. Approximate solutions for the pre-steady state behavior of the system are also determined using a Liouville transformation and corresponding asymptotic expansions. The short time regime shows power law decays of reactants. These decays will depend both on the dimensionality of the system as well as on the value of the rate constants associated with individual steps in the mechanism. Conditions can exist where a transformation to logarithmic oscillations will occur. Using this theoretical foundation a model is developed to analyze the kinetics of hydrogen isotope exchange kinetics in proteins. The exchange reaction is assume to occur in the boundary volume of the protein. Using the predicted fractal dimension of this boundary volume, scaling exponents are calculated and used as an unadjusted parameter. Highly accurate fits to the experimental data are achieved and activation energies are obtained that reflect the energetics of isotope exchange. This approach allows chemical kinetic behavior to be predicted from X-ray structure information.
Non-manual Focus Markers in Turkish Sign Language

Sign languages use syntactic (fronting, doubling, clefting), manual manipulations (variation in size, length, speed, repetition), and nonmanual markers (head and eyebrow movements) to mark focus. Due to their simultaneous nature, they are well-known for using these strategies together. In this study, we examined how the focus is marked in Turkish Sign Language (TİD) in free conversations and elicited data. Both studies’ most observed nonmanual markers are head nod and eyebrow raise. We propose that these nonmanual markers are not pure focus markers since they can cooccur with focus and topic in the structures. Yet, due to information structure, they are the marker of the phonological or intonational phrases. Furthermore, the duration of focal signs could be the marker of focus, which needs further investigation.
Aminoacetonitrile characterization in astrophysical-like conditions

Context. Aminoacetonitrile (AAN) has been detected in 2008 in the hot core SgrB2. This molecule is of particular interest because it is a central molecule in the Strecker synthesis of amino acids. This molecule can be formed from methanimine (CH2NH), ammonia (NH3) and hydrogen cyanide (HCN) in astrophysical icy conditions. Nevertheless, few studies exist about its infrared (IR) identification or its astrophysical characterization. Aims. We present in this study a characterization of the pure solid AAN and when it is diluted in water to study the influence of H2O on the main IR features of AAN. The reactivity with CO2 and its photoreactivity are also studied and the main products were characterized. Methods. Fourier transformed infrared (FTIR) spectroscopy of AAN molecular ice was performed in the 10–300 K temperature range. We used temperature-programmed desorption coupled with mass spectrometry detection techniques to evaluate the desorption energy value. The influence of water was studied by quantitative FTIR spectroscopy and the main reaction and photochemical products were identified by FTIR spectroscopy. Results. We determined that in our experimental conditions, the IR limit of AAN detection in the water ice is about 1 × 10 16 molecule cm −2 , which means that the AAN detection is almost impossible within the icy mantle of interstellar grains. The desorption energy of pure solid AAN is of 63.7 kJ mol −1 with ν0 to 10 28 molecule cm −2 s −1 , which implies that the presence of this molecule in the gas phase is only possible in hot cores. The glycine (Gly) formation from the AAN through the last step of the Strecker synthesis seems to be impossible in astrophysical-like conditions. Furthermore, AAN is photoresistant to vacuum ultra-violet radiation, which emphasizes the fact that AAN can be considered as a Gly reservoir molecule.
Meta-analysis of flavonoids use into beef and dairy cattle diet: Performance, antioxidant status, ruminal fermentation, meat quality, and milk composition

The objective of this study was to evaluate the effects of dietary supplementation with flavonoids (FLAs) on animal performance, diet digestibility, antioxidant status in blood serum, rumen parameters, meat quality, and milk composition in beef and dairy cattle through a meta-analysis. Thirty-six peer-reviewed publications were included in the data set. The weighted mean differences (WMD) between the FLAs treatments and the control treatment were used to assess the effect size. Dietary supplementation with FLAs decreased feed conversion ratio (WMD = −0.340 kg/kg; p = 0.050) and increased (p < 0.05) dry matter intake (WMD = 0.191 kg/d), dry matter digestibility (WMD = 15.283 g/kg of DM), and daily weight gain (WMD = 0.061 kg/d). In blood serum, FLAs supplementation decreased the serum concentration of malondialdehyde (WMD = −0.779 nmol/mL; p < 0.001) and increased (p < 0.01) the serum concentration of superoxide dismutase (WMD = 8.516 U/mL), glutathione peroxidase (WMD = 12.400 U/mL) and total antioxidant capacity (WMD = 0.771 U/mL). A higher ruminal propionate concentration (WMD = 0.926 mol/100 mol; p = 008) was observed in response to FLAs supplementation. In meat, the dietary inclusion of FLAs decreased (p < 0.05) shear force (WMD = −1.018 kgf/cm2), malondialdehyde content (WMD = −0.080 mg/kg of meat), and yellowness (WMD = −0.460). Supplementation with FLAs decreased milk somatic cell count (WMD = −0.251 × 103 cells/mL; p < 0.001) and increased (p < 0.01) milk production (WMD = 1.348 kg/d), milk protein content (WMD = 0.080/100 g) and milk fat content (WMD = 0.142/100 g). In conclusion, dietary supplementation with FLAs improves animal performance and nutrient digestibility in cattle. In addition, FLAs improve the antioxidant status in blood serum and the quality of meat and milk.
Comparison of two methods for removing baseline wander in the ECG

The authors compare the cubic-spline method with multipole null-phase digital filters in their ability to correct for baseline wander on 69 ECG segments with both normal and abnormal rhythms. A single-pole 0.05-Hz filter was included in this study for comparison. A null-phase, 6-pole filter with a cutoff between 0.75 and 1.0 Hz can attenuate low-frequency noise (i.e. correct baseline) as well as the cubic spline. However, such a filter introduces minor changes in the original signal, especially in the presence of a long RR interval. The cubic spline is very dependent on the accurate determination of QRS onset. However, both perform better than the single-pole 0.05-Hz filter, which does very little to attenuate low-frequency noise. <<ETX>>