Miracle-dz/UniFAR-FTUs huggingface dataset:
Cross-Speed State Monitoring of High-Speed Train Brake Pads Using Guided Deep Subdomain Adaptation

The brake pad plays a crucial role in the operation of high-speed train brake systems. However, it is prone to abnormal wear over prolonged periods of service, posing a safety risk to train operations. High-speed trains operate in environments with varying rotational speeds, which leads to features change of brake interface signals. Consequently, monitoring the state of brake systems across different rotation speeds becomes a challenging cross-domain recognition problem. To solve the substantial differences in vibration signals of brake pads at different rotation speeds, we propose a guided subdomain adaptation network for cross-speed state monitoring of brakes. By minimizing the distribution gaps between relevant subdomains, our network effectively aligns the feature distributions in different rotation speeds of brake pad. Besides, a training guidance mechanism is designed to significantly reduce the misclassification of pseudolabels for target signals, facilitating more accurate identification of the appropriate common subspace for consistent-labeled subdomains. We validate the practicality of our approach under balanced datasets, small sample conditions, and noisy environments. The experimental results demonstrate that the proposed method can achieve cross-rotation speed state monitoring of high-speed train brake systems even with minimal labeled samples and exhibit superior stability and accuracy compared to other transfer learning algorithms in cross-domain state monitoring.
SAFEGUARDING INNOCENCE: DEVELOPING CURRICULUM OF ISLAMIC SEXUAL EDUCATION IN EARLY CHILDHOOD

Article 15 of Law No. 35/2014 affirms the right of every child to be protected from various forms of exploitation, including sexual crimes. A well-structured and age-appropriate Islamic sexuality education curriculum plays an important role in shaping a healthy understanding of children's physical, emotional, and social interactions. This research reviews the development of a sexuality education curriculum using the Dick and Carey development model in an Early Childhood Education (ECE) or Kindergarten B unit that refers to the Merdeka Curriculum. This curriculum includes four learning domains, namely intellectual skills, verbal information, psychomotor skills, and attitudes, which are in line with the Learning Outcomes of religious values and character, identity, and the basics of literacy and Steam. The learning design process begins with goal identification through performance analysis and needs assessment, then designing learning objectives that address specific challenges. The curriculum contains two themes, namely Showing Appropriate Reactions to Verbal Harassment and Inappropriate Touching which has 13 learning outcomes and Maintaining Cleanliness and Hygiene of Sensitive Body Parts which has 5 learning outcomes. The media needed to support learning include videos, picture storybooks, cards, snakes and ladders games, puppets, and songs. The appropriate methods are storytelling, socio-drama, interactive games, and discussions. The product was validated by material and curriculum experts. After revision, the values achieved showed improvement,with the Curriculum and Learning Evaluation Expert Assessment increasing from 3.06 to 3.74, reflecting increased suitability and effectiveness. The Early Childhood Sexuality Education Material Content Expert Assessment progressed from 3.08 to 3.67, highlighting improved inclusivity and accuracy.
New Algorithm for Dense Subset-Sum Problem

— A new algorithm for the dense subset-sum problem is derived by using the structural characterization of the set of subset-sums obtained by analytical methods of additive number theory. The algorithm works for a large number of summands (m) with values that are bounded from above. The boundary (€) moderately depends on m. The new algorithm has 0(ra7/4/log3/4 m) time boundary that is faster than the previously known algorithms the best of which yields 0(m2/ log2 m).
How pondscapes function: connectivity matters for biodiversity even across small spatial scales in aquatic metacommunities

Habitat loss and fragmentation are growing global threats to natural habitats and their networks, posing significant challenges to biodiversity conservation. Globally, ponds are sharply declining in number because their small size makes them highly vulnerable to land use changes. While it is generally agreed that connectivity in habitat networks is crucial for sustaining biodiversity, the effect of connectivity on biodiversity patterns over small‐scaled habitat networks has so far received less attention given the general assumption that metacommunities lack spatial structuring on small scales. In this study, we tested whether this holds for multiple passively and actively dispersing organism groups in a well‐delineated pond metacommunity of 54 bomb crater ponds situated within 1 km. We investigated the influence of space and environment on species richness and metacommunity structure in these ponds, which share similar age, size, and shape and are subject to strong environmental gradients, making it an ideal study system. We specifically examined the impact of network centrality on taxonomic richness and eigenvector‐based spatial arrangement on metacommunity structure across different organism groups, including prokaryotes, microeukaryotes, zooplankton, macroinvertebrates, and amphibians. We found that while environmental filtering is the primary driver of community dynamics, there is also a significant spatial signal, particularly for passively dispersing groups, demonstrating the role of the central‐peripheral connectivity gradient. These findings highlight the importance of studying and protecting ponds as parts of a network rather than focusing on individual ponds.
Subcentimetric Papillary Thyroid Carcinoma: Does the Diagnosis Kind Impact Prognosis?

Introduction: Subcentimetric papillary thyroid carcinoma (SPTC) (papillary thyroid carcinoma with less than 10 mm in size) usually presents an excellent prognosis, with few aggressive reported cases. Given the globally increased incidence of SPTC, physicians are struggling with the need to identify prognostic factors to stratify SPTC. The aim was to compare clinicopathological variables and prognosis between clinically and incidentally diagnosed SPTC. Materials and methodsː This is a retrospective observational study on patients with SPTC who underwent thyroidectomy between 2002 and 2015. Two groups were considered: G1 (n=60 (61.9%)), clinical diagnosis (Bethesda III-VI cytology in the thyroid tumor/in cervical lymphadenopathies) and G2 (n=37 (38.1%)), incidental diagnosis (thyroidectomy for benign thyroid pathology). The histological material was reviewed, and molecular analysis of the BRAF, RAS, and TERT promoter (TERTp) genes was performed. Resultsː Ninety-seven individuals were included, 60 (61.9%) of which were from G1, with a predominance of female sex (n=83 (85.6%)). Individuals of G1 were younger (53.0±14.2 versus 59.3±13.9 years; p=0.035), were more frequently treated with 131-iodine (39.2% versus 13.4%; p=0.007), had the largest diameter (8 (p25-p75: 7-9) versus 5 (p25-p75: 4-6.5) mm; p<0.001), and higher frequency of minimal extracapsular invasion (45% versus 24.3%; p=0.041). Increased tumor size was the only independent predictor of a clinical diagnosis (p<0.001). Conclusionsː Clinically and incidentally diagnosed SPTC showed excellent medium- to long-term prognosis. A larger SPTC was more likely a driver of clinical detection than a marker of tumor aggressiveness, but caution should be taken as contradictory data persists.
The tectonic and geodynamic evolution of New Caledonia: a view | Point de vue sur l'evolution tectonique et geodynamique de la Nouvelle-Caledonie (Pacifique, France)

From the Permian to late Jurassic, plutonic and volcanosedimentary terranes were formed in intra-oceanic arc settings; then, these were obducted onto the "pre-Permian' metamorphic terrane and finally accreted to the east Gondwana margin in latest Jurassic times. In the late Cretaceous and Paleocene, the continuing break of the Gondwana margin resulted in the rifting of oceanic plateaus which finally reached the Eocene subduction zone of the Loyalty basin. Consequently, the subduction was blocked, ophiolotic rocks were obducted in the late Eocene, and several intraoceanic thrusts occurred. -from English summary
SER COMPETITIVO SEM DEIXAR DE SER COOPERATIVO: PROPOSTA DE ANÁLISE SISTÊMICA PARA O DILEMA DAS COOPERATIVAS

As adversidades tem, geralmente, a capacidade de gerarem comportamentos que agregam individuos. O objetivo deste ensaio e propor uma estrutura analitica usando as abordagens do empreendedorismo social, a cultura, o conhecimento e a cooperacao, para tratar, de forma sistemica, o dilema da competitividade para cooperativas agricolas. O entendimento dessa estrutura e que o empreendedorismo social, que sustenta organizacoes como as cooperativas, trazem consigo elementos de cultura, conhecimento e postura cooperativa que tendem a influenciar o desempenho da organizacao atraves de sua presenca nos demais fatores internos. A concepcao basica de uma organizacao cooperativa e o seu diferencial mais importante, pois pressupoe que a finalidade do sistema seja maior do que apenas as de cunho economico-financeiro. Enquanto as organizacoes, em geral, precisam construir um sistema de valores que incorpore aspectos socio-ambientais em sua estrutura, organizacoes cooperativas sao estruturadas sobre um sistema de valores desse tipo.
New use of preoperative fibrinogen in ovarian cancer management

Background Ovarian cancer (OC) is often diagnosed at an advanced stage due to the absence of specific symptoms in its early stages. And the prognosis greatly depends on when the disease is diagnosed. Thus, we conducted to evaluate the value of preoperative fibrinogen (Fib) levels for the diagnosis of OC in the hope of improving its diagnostic efficiency. Methods A total of 126 ovarian tumor patients were retrospectively included in this study. Four candidate OC markers, including cancer antigen 125 (CA125), Fib, platelet (PLT) and homocysteine (Hcy) were employed to establish a diagnosis model for OC. The diagnostic performance of the model was evaluated using the area under the receiver operating characteristic curve (AUC) and Youden index. Results All included markers could be used for the diagnosis of OC. The AUCs of CA125, Fib, PLT and Hcy were 0.881, 0.825, 0.676 and 0.647, respectively. The new diagnosis model combining CA125 and Fib (CA125-Fib) had a higher AUC (0.924), Youden index (0.730), and best sensitivity (SN) (74.6%) and specificity (SP) (98.41%). CA125-Fib also had a high value in the diagnosis of stage I–II OC (AUC, Youden index, SN and SP: 0.853, 0.624, 81.48% and 80.95%). Conclusions Fib could be used for OC diagnosis. In particular, the combination of Fib and CA125 could further improve the diagnostic efficiency. And the diagnostic value of PLT and Hcy was found to be poor.
Association between Serum Free Fatty Acids and Clinical and Laboratory Parameters in Acute Heart Failure Patients

Very little is known about the association between individual serum free fatty acids (FFAs) and clinical and laboratory parameters (indicators of heart failure severity) in acute heart failure (AHF) patients. Here, the baseline serum levels of FFAs, 16:0 (palmitic acid), 16:1 (palmitoleic acid), 18:0 (stearic acid), 18:1 (oleic acid), 18:2 (linoleic acid), 18:3 (alpha-linolenic acid or gamma-linolenic acid), 20:4 (arachidonic acid), 20:5 (eicosapentaenoic acid), and 22:6 (docosahexaenoic acid), were determined in 304 AHF patients (94.7% belonged to New York Heart Association functional class IV) using gas chromatography. Spearman correlation coefficients were used to examine the associations between the individual and total (the sum of all FFAs) FFAs and clinical and laboratory parameters. After applying a Bonferroni correction to correct for multiple testing, the total FFAs, as well as the individual FFAs (except FFAs 18:0, 20:5, and 22:6), were found to be significantly positively correlated with serum albumin. Only a few additional associations were found: FFA 16:0 was significantly negatively correlated with systolic pulmonary artery pressure, FFA 18:3 was significantly negatively correlated with C-reactive protein and body mass index, and FFA 20:4 was significantly negatively correlated with blood urea nitrogen. Based on our results, we conclude that in patients with severe AHF, individual and total serum FFAs are slightly associated with established laboratory and clinical parameters, which are indicators of heart failure severity.
La localisation et la magnitude du séisme du 5 février 1663 (Charlevoix) revues à l’aide des mouvements de terrain11Version initiale présentée à la 4e Conférence canadienne sur les géorisques, Québec, mai 2008.

Le seisme du 5 fevrier 1663 est le premier seisme historique violent au Canada dont la magnitude M est estimee comme etant autour de 7. Il a laisse dans le paysage plusieurs signatures qui en revelent l’etendue et l’intensite. Cote terrestre, on note des glissements de terrain dans diverses regions du Quebec dont la region de Betsiamites, du Saguenay, de Charlevoix et de la Mauricie. Cote subaquatique, plusieurs signatures de mouvements de terrain ont ete attribuees a ce seisme, particulierement le long de l’estuaire du Saint-Laurent, du fjord du Saguenay et quelques lacs localises sur le Bouclier laurentien et probablement dans les Appalaches. Le volume minimum cumule des glissements de terrain associes au seisme de 1663 est de 1,7 km3. A partir de l’analyse des donnees reliees aux mouvements de terrain causes par le seisme, et de l’utilisation de methodes empiriques pour l’estimation de la magnitude, la localisation de l’epicentre proposee du seisme serait situee sur le Bouclier canadien au nord du Sain.
Study on radar electronic module cooling by using diamond/copper composites

Abstract Diamond/copper composites are regarded as a new generation of heat dissipation materials because of their good thermal conductivity and matched thermal expansion coefficient to semiconductor materials. This study focuses on the thermal application study of the diamond/copper composite. A diamond/copper composite cooling module was designed to meet the requirements of thermal physical properties of an electronic device. The heat conduction resistance of diamond/copper substrate was calculated theoretically. It is found that the optimum thickness of diamond/copper substrate is about 0.34 times of the equivalent radius and improving the thermal conductivity of the substrate is more effective for heat dissipation when the thermal convective resistance is low. When the heat flux of the chip is 100 W/cm2, the temperature of the chip using diamond/copper composite as substrate is 4.84 °C lower than that using silicon aluminum alloy. The improvement effect increases about 5 °C when the heat flux increases by 100 W/cm2.
Unveiling the Immunogenicity of Ovarian Tumors as the Crucial Catalyst for Therapeutic Success

Simple Summary Tumor immunogenicity is one of the main factors influencing responses to cancer therapies and long-lasting antitumoral immunity. In this review, we will cover how classic and non-classic Major Histocompatibility Complex (MHC) class I molecules influence tumor composition and prognosis. Moreover, we explore other components of the tumor microenvironment such as the epithelial to mesenchymal transition of ovarian cancer cells. Then, we highlight key therapeutic strategies to overcome the lack of ovarian cancer immunogenicity and we address some open questions remaining that need further investigation in this field. Abstract Epithelial ovarian cancer (EOC) is the most lethal gynecologic cancer. The disease is often diagnosed after wide-spread dissemination, and the standard treatment combines aggressive surgery with platinum-based chemotherapy; however, most patients experience relapse in the form of peritoneal carcinomatosis, resulting in a 5-year mortality below 45%. There is clearly a need for the development of novel treatments and cancer immunotherapies offering a different approach. Immunotherapies have demonstrated their efficacy in many types of cancers; however, only <15% of EOC patients show any evidence of response. One of the main barriers behind the poor therapeutic outcome is the reduced expression of Major Histocompatibility Complexes class I (MHC I) which occurs in approximately 60% of EOC cases. This review aims to gather and enhance our current understanding of EOC, focusing on its distinct cancer characteristics related to MHC I expression, immunogenicity, antigen presentation, epithelial-to-mesenchymal transition, and various ongoing immunotherapeutic strategies designed to stimulate antitumor immunity.
The Efficacy of Immunotherapy and Clinical Utility of Comprehensive Genomic Profiling in Adenoid Cystic Carcinoma of Head and Neck

Background and Objectives: Adenoid cystic carcinoma (ACC) of the head and neck is generally slow-growing but has a high potential for local recurrence and metastasis to distant organs. There is currently no standard pharmacological treatment for recurrent/metastatic (R/M) ACC, and there are cases in which immune checkpoint inhibitors (ICIs) are administered for ACC according to head and neck squamous cell carcinoma (HNSCC). However, the efficacy of ICIs for ACC remains unclear, and the predictive biomarkers need to be elucidated. Materials and Methods: The Center for Cancer Genomics and Advanced Therapeutics (C-CAT) database enabled the retrospective but nationwide analysis of 263 cases of ACC of the head and neck. Then, we examined and reported four cases of ACC that received ICIs and comprehensive genomic profiling (CGP) in our institution. Results: The C-CAT database revealed that 59 cases out of 263 received ICIs, and the best response was 8% of objective response rate (ORR) and 53% of disease control rate (DCR) (complete response, CR 3%, partial response, PR 5%, stable disease, SD 44%, progressive disease, PD 19%, not evaluated, NE 29%). The tumor mutational burden (TMB) in ACC was lower overall compared to HNSCC and could not be useful in predicting the efficacy of ICIs. Some cases with MYB structural variants showed the response to ICIs in the C-CAT database. A patient with MYB fusion/rearrangement variants in our institution showed long-term stable disease. Conclusions: ICI therapy is a potential treatment option, and the MYB structural variant might be a candidate for predictive biomarkers for immunotherapy in patients with R/M ACC.
Pathophysiology, diagnosis and management of cerebral venous thrombosis: A comprehensive review

Cerebral venous thrombosis is a rare cause of stroke in young mostly female adults which is frequently overlooked due to its variable clinical and radiological presentation. This review summarizes current knowledge on it risk factors, management and outcome in adults and highlights areas for future research. Females are 3 times more commonly affected and are significantly younger than males. The presenting symptoms can range from headache to loss of consciousness. However, the often-nebulous nature of symptoms can make the diagnosis challenging. Magnetic resonance imaging with venography is often the diagnostic imaging of choice. While unfractionated or low molecular-weight heparin is the mainstay of treatment, endovascular intervention with thrombolysis or thrombectomy and decompressive craniectomy may be required depending on clinical status. Nevertheless, approximately 80% of patients have a good recovery but mortality rates of −5% to 10% are not uncommon. Diagnosing cerebral venous thrombosis can be challenging but with vigilance and expert care patients have the best chance of a good clinical outcome.
Regional distribution and relevance in paleonvironmental studies of lakes in the Tatra Mts. (Western Carpathians)

Scientific limnological research in the Tatra Mountains were initiated by Stanislaw Staszic in the early XIX century. After the World War II, the evolution of Tatra lakes was investigated by Kondracki, Klimaszewski, Baumgart-Kotarba and. Extensive paleolimnological investigations in the Tatra Mountains were started by the group of scientists led by K. Starmach in the beginning of the second half of the 20 th century. There has been not much research concerned to the regional distribution of lakes and their properties in the Tatra Mountains (Pociask-Karteczka 2013). Very early division of lakes presented A. Gadomski (1922), which distinguished four types of lakes: a) tarns (cirque lake or corrie loch), b) bedrock-dammed lakes, c) moraine lakes. This division was concerned in subsequent publications (Choinski 2007). M. Luknis (1973, 1985) recognized additional types: kettles and landslide-dammed lakes and M. Klimaszewski (1988) – inter-sheepback lakes. J. Pacl and K. Wit-Joźwik in Klima Tatier (Pacl, Wit-Joźwik 1974) were focused on the temperature of water in lakes in Polish and Slovak parts and M. Borowiak (2000a,b) provided a comprehensive analysis of types, dimensions, temperature and chemical composition of water in lakes in the Tatra Mountains. According to present day state of knowledge, one may distinguish following genetic types of lakes: I) glacial, II) not-glacial. There are four types of the glacial origin lakes in the Tatra Mountains (Fig. 1): a) tarns (cirque lakes or corrie loch), b) bedrock-moraine dammed lakes, c) inter-sheepback lakes, d) moraine lakes, e) kettles. Most of lakes in the Tatra Mountains are tarns and bedrock-moraine dammed lakes, and they are located at the elevation over 1400 m a.s. l. in the Western Tatra Mountains, and over 1600 m a.s. l. in the High Tatra Mountains. Some of them are paternoster lakes – a series of stair-stepped lakes formed in individual rock basins aligned down the course of a glaciated valley. Lakes in the Five Polish Lakes Valley is an example of such type. The inter-sheepback lakes occur at higher elevations (e.g. Wyznie Mnichowe Stawki, Zamrznute oka). There is a little number of moraine lakes in the Tatra Mountains (e.g. Smreczynski, Toporowy Nizni) and kettles (e.g. Strbske Pleso, Kotlinowy Stawek). Some lakes are located among rock debris or rock debris and moraine material (Dwoisty Staw Gąsienicowy, Anitino ocko) – they are of polygenetic origin.
MODEL SELF-DISCLOSURE GENERASI Z PENGGUNA BERAT MEDIA SOSIAL

Based on the results of previous research, it was found that Instagram, Twitter, TikTok, YouTube, Discord, and also Facebook became the social media most often used by Generation Z as heavy users of social media in conducting self-disclosure. Self-disclosure is divided into negative and positive, positive things become open areas that are shared and can be known by many people, while negative things are the opposite. Generation Z as heavy users of social media conduct self-disclosure about various personal information accurately and honestly through social media, this is done consciously with the aim of building relationships with other people. Therefore, this study was conducted with the aim of describing and analyzing the self-disclosure model of Generation Z heavy users on social media. The research method uses a qualitative approach with phenomenological methods. Data collection was carried out using focus group discussion techniques, with the selection of resource persons based on pre-determined criteria. The results showed that the self-disclosure model of generation Z who became heavy users of social media had the largest proportion in terms of valence, intimacy, and intention.