Miracle-dz/UniFAR-FTUs huggingface dataset:
Bacterial coinfections in COVID: Prevalence, antibiotic sensitivity patterns and clinical outcomes from a tertiary institute of Northern India

Purpose: Bacterial coinfections are a leading cause of morbidity and mortality during viral infections including corona virus disease (COVID-19). The COVID-19 pandemic has highlighted the need to comprehend the complex connection between bacterial and viral infections. During the current pandemic, systematic testing of the COVID-19 patients having bacterial coinfections is essential to choose the correct antibiotics for treatment and prevent the spread of antimicrobial resistance (AMR). This study was planned to study the prevalence, demographic parameters, comorbidities, antibiotic sensitivity patterns, and outcomes in hospitalized COVID-19 patients with bacterial coinfections. Material and Methods: The COVID-19 patients having bacterial coinfections were selected for the study and analyzed for the prevalence, antibiotic sensitivities, comorbidities, and clinical outcomes. The bacterial isolates were identified and the antibiotic susceptibility testing was performed according to the Clinical and Laboratory Standards Institute (CLSI) guidelines. Results: Of the total 1,019 COVID-19 patients screened, 5.2% (n = 53) demonstrated clinical signs of bacterial coinfection. Escherichia coli were the most common isolate followed by Pseudomonas aeruginosa and Klebsiella spp. among the gram-negative bacterial infections. Coagulase-negative Staphylococcus species (CONS) and Staphylococcus aureus were most common among the gram-positive bacterial infections. The antibiotic sensitivity profiling revealed that colistin (99%), imipenem (78%), and fosfomycin (95%) were the most effective drugs against the gram-negative isolates while vancomycin (100%), teicoplanin (99%), and doxycycline (71%) were most potent against the gram-positive isolates. The analysis of the clinical parameters and outcomes revealed that among the COVID-19 patients with bacterial coinfections, the mortality rate was higher (39%) than the control group (17%) (P-value < 0.001). Conclusion: This study reveals the significantly increased rates of bacterial coinfections among COVID-19 patients which may lead to an increase in mortality. This study will guide the physicians at the primary level on the rational and correct usage of antibiotics in such COVID cases. Hence, systematic testing of COVID-19 patients with bacterial coinfections is the need of the hour to decrease the mortality rate and limit the spread of AMR.
High-Quality Inclusion in Preschool Settings: A Survey of Early Childhood Personnel

We utilized a survey to explore how early childhood personnel delivered high-quality and inclusive preschool special education and related services to young children with disabilities in one U.S. Western state. We conducted quantitative analyses on 418 participants’ survey responses, including t tests and Mann Whitney tests to examine differences in the use of high-quality inclusion practices between early childhood special educators (ECSEs) (n = 209) and related service personnel (RSP) (n = 209). Findings indicated that ECSEs were more likely than RSP to implement high-quality inclusion practices. All personnel reported inconsistent use of teaming practices. Services were provided most often inside the classroom with peers; however, several personnel provided support to children inside their classroom but in a separate space or outside of their classroom. We discuss findings in the context of ways in which early childhood personnel can be supported to use high-quality inclusion practices.
An Efficient Multichannel SAR Channel Phase Error Calibration Method Based on Fine-Focused HRWS SAR Image Entropy

Azimuth multichannel synthetic aperture radar (SAR) is a useful approach to solving minimum antenna area constraint and realizing high resolution and wide swath (HRWS) imaging by multichannel signal reconstruction. However, channel phase error will significantly degrade the reconstruction performance and leads to azimuth ghost. This article presents an efficient minimum entropy channel error estimation method based on fine-focused SAR image. The multichannel SAR images are obtained by using Range-Doppler imaging algorithm applied for preprocessed data of each channel. Then, the reconstruction and the residual range cell migration and residual second range compression compensation are performed to achieve multichannel fine-focused SAR images. After overlapping these multichannel fine-focused SAR images and iteratively calibrating the channel phase error, fine-focused HRWS SAR image can be achieved. Therefore, the SAR image used in the channel error estimation process can directly obtain the fine focused HRWS SAR image after minimum entropy iteration without additional imaging operations. Compared with the minimum entropy method by using the coarse-focused SAR image based on azimuth deramp, redundant reconstruction, and imaging operations are avoided. Thus, error estimation and imaging processing procedures are optimized. Processing efficiency improvement are analyzed, and simulation and acquired data processing verify the effectiveness of the proposed method.
A detector of gravitational waves based on coupled microwave cavities

Since 1978 superconducting coupled cavities have been proposed as sensitive detector of gravitational waves. The interaction of the gravitational wave with the cavity walls, and the resulting motion, induces the transition of some electromagnetic energy from an initially excited cavity mode to an empty one. The energy transfer is maximum when the frequency of the wave is equal to the frequency difference of the two cavity modes. In this paper the basic principles of the detector are discussed. The interaction of a gravitational wave with the cavity walls is studied in the proper reference frame of the detector, and the coupling between two electromagnetic normal modes induced by the wall motion is analyzed in detail. Noise sources are also considered; in particular the noise coming from the brownian motion of the cavity walls is analyzed. Some ideas for the developement of a realistic detector of gravitational waves are discussed; the outline of a possible detector design and its expected sensitivity are also shown.
Advanced Fabrication of miRNA-Based Electrochemical Nanobiosensor for Diagnosis of Breast Cancer

Early diagnosis is the key to easy, low cost, and effective treatment of breast cancer. Therefore, studies have been accelerated to identify breast cancer diagnostic biomarkers and diagnose cancer before it progresses. The use of miR-155 as a potential biomarker in breast cancer, which has different levels at different stages of the disease, provides a simple serological test for breast cancer prognosis/diagnosis, follow-up, and treatment. Nanopolymers containing different functional groups that are formed by thiol affinity technique were synthesized by mini emulsion polymerization method and advanced characterization studies were carried out in this study to be used as bioactive layers in the nanobiosensor system for miRNA detection. The working conditions of the electrochemical nanobiosensor in which nanopolymers are used as bioactive layers were optimized. Analytical measurement characteristics and validation studies of the nanobiosensor were determined and analysis was performed on commercial blood serum. The potential of the developed electrochemical biosensor to be used as a medical diagnostic kit was explained by comparing it with commercial miRNA kit currently used for the detection of miR-155. This novel nanobiosensor provide sensitive, reliable, and rapid detection of miR-155 and it can provide the potential for breast cancer early diagnosis, prognosis, and follow-up.
Chitosan–Gelatin Films: Plasticizers/Nanofillers Affect Chain Interactions and Material Properties in Different Ways

Biopolymers, which are biodegradable and inherently functional, have high potential for specialized applications (e.g., disposable and transient systems and biomedical treatment). For this, it is important to create composite materials with precisely defined chain interactions and tailored properties. This work shows that for a chitosan–gelatin material, both glycerol and isosorbide are effective plasticizers, but isosorbide could additionally disrupt the polyelectrolyte complexation (PEC) between the two biopolymers, which greatly impacts the glass transition temperature (Tg), mechanical properties, and water absorption. While glycerol-plasticized samples without nanofiller or with graphene oxide (GO) showed minimal water uptake, the addition of isosorbide and/or montmorillonite (MMT) made the materials hydrolytically unstable, likely due to disrupted PEC. However, these samples showed an opposite trend in surface hydrophilicity, which means surface chemistry is controlled differently from chain structure. This work highlights different mechanisms that control the different properties of dual-biopolymer systems and provides an updated definition of biopolymer plasticization, and thus could provide important knowledge for the future design of biopolymer composite materials with tailored surface hydrophilicity, overall hygroscopicity, and mechanical properties that meet specific application needs.
Experimental Study of 17O(p,α)14N and 17O(p,γ)18F for Classical Nova Nucleosynthesis

We investigated the proton‐capture reactions on 17O occuring in classical nova explosions. We observed a previously undiscovered resonance at ERlab=194.1±0.6 keV in the 17O(p,α)14N reaction, with a measured resonance strength ωγpα=1.6±0.2 meV. We studied in the same experiment the 17O(p,γ)18F reaction by an activation method and the resonance‐strength ratio was found to be ωγpα/ωγpγ=470±50. The corresponding excitation energy in the 18F compound nucleus was determined to be 5789.8±0.3 keV by γ‐ray measurements using the 14N(α,γ)18F reaction. These new resonance properties have important consequences for 17O nucleosynthesis and γ‐ray astronomy of classical novae.
An Integer Programming Approach to Packing Lightpaths on WDM Networks

We consider a routing and wavelength assignment (RWA) for the efficient operation of WDM networks. For a given physical network, a set of selected pairs of nodes, the number of required connections for each selected pair of nodes, and a set of available wavelengths, the RWA is to realize as many connections as possible without wavelength collision. We give an integer programming formulation and an algorithm based on column generation. Though the proposed algorithm does not guarantee optimal solutions, test results show that the algorithm gives probably good solutions.
Evaluation of seed morphology, seedling genetic variation, and components for seed storage of Agave landraces of commercial interest

Abstract Sexual propagation of Agave plants is an incipient cultivation method, these plants withstand drought and adverse growing conditions; therefore, research on Agave’s diversity, seed processing, and storage could support its cultivation on marginal lands. The aim of this work was to evaluate seed morphology, germination, and seedling genetic diversity of six seed origins (species × provenance) of Agave plants collected in five provenances from Mexico. Seed longevity was evaluated in two seed origins after a 10-year storage period. Seed morphology and seedling genetic variation results demonstrated intra- and interspecific variation within Agave salmiana and with the other seed origins, respectively. After a 10-year storage period seed germination of two A. salmiana seed origins remained relatively stable, storage conditions, and seed variables of this work can serve as reference parameters for future analyses. To the best authors’ knowledge, this is the first report of Agave’s seed longevity evaluation after a 10-year storage period.
Fundamental Issues and Problems in the Realization of Memristors

In 2008, researchers at the Hewlett-Packard (HP) laboratories claimed to have found an analytical physical model for a genuine memristor device [1]. The model is considered for a thin TiO_2 film containing a region which is highly self-doped with oxygen vacancies and a region which is less doped, i.e., a single-phase material with a built-in chemical inhomogeneity sandwiched between two platinum electrodes. On base of the proposed model, Strukov et al. [1] were able to obtain the characteristic dynamical state equation and current-voltage relation for a genuine memristor. However, some fundamental facts of electrochemistry have been overlooked by the authors while putting forward their model, namely the coupling of diffusion currents at the boundary between both regions. The device will operate for a certain time like a "chemical capacitor" until the chemical inhomogeneity is balanced out, thus violating the essential requirement on a genuine memristor, the so-called "no energy discharge property". Moreover, the dynamical state equation for the HP-memristor device must fail as this relation violates by itself Landauer's principle of the minimum energy costs for information processing. Maybe, such an approach might be upheld if one introduces an additional prerequisite by specifying the minimum amount of electric power input to the device which is required to continuously change internal, physical states of the considered system. However, we have reasonable doubts with regard to this.
Radio-Oxidation Ageing of XLPE Containing Different Additives and Filler: Principal Component Analyses of Gases Emission and Consumption

In the context of lifetime extension of Nuclear Power Plants (NPPs), electric cable ageing has to be checked to evaluate their performance during normal operation. These electric cables are complex materials, with a conductor and insulating shield in the metal and insulating layer and sheath in the polymer; the most sensitive layer is commonly considered to be the insulating layer. The ageing mechanism upon irradiation under oxidative conditions has been evaluated using gas mass spectrometry and the first conclusions have been drawn. Nonetheless, the data obtained are very numerous and complex; thus, the objective of this new article regards these experimental results using mathematical tools. It allowed confirmation of all the results obtained on these materials, but using chemometrics, i.e., statistical/mathematical analyses, of the results. Using these powerful mathematical tools gives strength to the analyses realised and to the conclusions obtained.
45 minutters bevægelse i undervisningen som et led i den danske skolereform

I skoleåret 2014/15 trådte en ny skolereform i kraft, hvor bevægelse fik en fremtrædende rolle med lovkravet om 45 minutters daglig bevægelse integreret i undervisningen. Det er nu snart syv år siden, reformen trådte i kraft, og resultater viser, at mange skoler endnu ikke har formået at få realiseret lovkravet. Det kan der være flere årsager til, men klart er det, at decentralisering af implementeringsansvaret ikke ser ud til at have været tilstrækkeligt. En fælles implementeringsunderstøttelse ville formentlig have været til stor gavn for skolerne.
On Fenchel–Nielsen Coordinates of Surface Group Representations into SU(3,1)

Abstract Let Σg be a compact, connected, orientable surface of genus g ≥ 2. We ask for a parametrisation of the discrete, faithful, totally loxodromic representations in the deformation space Hom(π1(Σg), SU(3, 1))/SU(3, 1). We show that such a representation, under some hypothesis, can be determined by 30g − 30 real parameters.
Does the Stage of University Education Differentiate Midwifery Students in Terms of Their Behaviors in Certain Situations and Sense of Self-Efficacy?

Midwifery students’ behaviors in relevant spheres of their lives, as well as their sense of self-efficacy, can affect the process of training in the midwifery profession. The aim of the study was to determine the behaviors of students in Poland, assessed in a situational context, as well as their sense of self-efficacy in correlation with these behaviors at different levels of education in the midwifery profession. The study group included first- and third-year bachelor’s degree (BS) midwifery students, as well as master’s degree (MS) midwifery students. The survey was conducted on 1031 students. The ‘Inventory for Personality Assessment in Situations’ (IPS) and the General Self-Efficacy Scale (GSES) were used in the study. The largest group of students that were categorized as having problematic profiles was observed in the social-communicative domain, which indicates the necessity of introducing corrective and therapeutic actions concerning their interpersonal relations. The leading trait in the social-communicative domain among the BS students was sensitivity to frustration. The lowest self-confidence was observed among the third-year BS students. The average result of generalized self-efficacy among all the respondents was M = 28.36 (SD = 4.41), which indicates the average level of the obtained results. Students at different stages of midwifery programs demonstrate different behaviors when assessed in the situational context.
Entangled black holes as ciphers of hidden information

Institute of Physics, Jagiellonian University, 30-059 Krakow, Poland andCenter for Theoretical Physics, Polish Academy of Science, 02-668 Warszawa, Poland(Dated: July 4, 2009)The black-hole information paradox has fueled a fascinating eﬀort to reconcile the predictions ofgeneral relativity and those of quantum mechanics. Gravitational considerations teach us that blackholes must trap everything that falls into them. Quantum mechanically the mass of a black hole leaksaway as featureless (Hawking) radiation. However, if Hawking’s analysis turned out to be accuratethen the information would be irretrievably lost and a fundamental axiom of quantum mechanics,that of unitary evolution, would likewise fail. Here we show that the information about the matterthat collapses to form a black hole becomes encoded into pure correlations within a tripartitequantum system, the quantum analog of a one-time pad until very late in the evaporation, providedwe accept the view that the thermodynamic entropy of a black hole is due to entropy of entanglement.In this view the black hole entropy is primarily due to trans-event horizon entanglement betweenexternal modes neighboring the black hole and internal degrees of freedom of the black hole.
What Is the Place of Physical Education among the Teaching Priorities of Primary School Teachers? An Empirical Study on Importance, Qualification and Perceived Teachers’ Competence

The education of children is important because it determines the future of the world. Teachers have a great responsibility for this, which applies to every subject taught. In this regard, teachers usually specialize in a specific area and greatly influence how the subject is taught and how students gain a view of the subject. The present study aimed to investigate teachers’ attitudes about subjects in primary school, with a particular focus on physical education. The sample of participants (N = 111) included Croatian female primary school teachers with a mean age of 47.88 (±8.11 SD) years and a mean teaching experience of 21.83 (±10.24 SD) years. The variable sample consisted of a three-criteria questionnaire for the assessment of classroom subjects: (i) the importance of a subject (importance); (ii) the level of qualifications obtained during study for a subject (qualification); and (iii) the teacher’s competence for teaching (competence). Significant differences were found in the assessment of classroom subjects. The group of core academic subjects has noticeably higher assessments than the group of practical and artistic subjects. The assessment of teachers’ competence in PE teaching is the lowest of all the classroom subjects. Further research of classroom teachers’ attitudes towards the implementation of physical education is advised, with an increased number of participants and the inclusion of new measures.
Plants in Microgravity: Molecular and Technological Perspectives

Plants are vital components of our ecosystem for a balanced life here on Earth, as a source of both food and oxygen for survival. Recent space exploration has extended the field of plant biology, allowing for future studies on life support farming on distant planets. This exploration will utilize life support technologies for long-term human space flights and settlements. Such longer space missions will depend on the supply of clean air, food, and proper waste management. The ubiquitous force of gravity is known to impact plant growth and development. Despite this, we still have limited knowledge about how plants can sense and adapt to microgravity in space. Thus, the ability of plants to survive in microgravity in space settings becomes an intriguing topic to be investigated in detail. The new knowledge could be applied to provide food for astronaut missions to space and could also teach us more about how plants can adapt to unique environments. Here, we briefly review and discuss the current knowledge about plant gravity-sensing mechanisms and the experimental possibilities to research microgravity-effects on plants either on the Earth or in orbit.
Exercise on Striatal Dopamine Level and Anxiety-Like Behavior in Male Rats after 2-VO Cerebral Ischemia

The purpose of this study was to discuss the effect of voluntary wheel running on striatal dopamine levels and anxiety-like behavior in rats with global cerebral ischemia. The male Sprague-Dawley rats were signed on in this study and randomly divided into following 4 groups: Control group (C group), Sham group (S group), ischemia group (I group), and 3 weeks physical exercise before ischemia group (3RI group). The rats in the 3RI group were placed in a voluntary running wheel for three weeks to exercise. Then, the rats in I and 3RI groups received bilateral carotid artery ligation (2-VO) operation. The C and S group did not perform voluntary running exercise and the bilateral common carotid arteries of S group were exposed without ligation. In vivo microdialysis was used in conjunction with high performance liquid chromatography (HPLC) and electrochemical detection to ascertain the level of dopamine in the striatum. Elevated plus maze (EPM) and open field (OF) were used to test anxiety status at 24 hours and 7days after 2-VO cerebral ischemia. Meanwhile, gait and motor coordination evaluations were carried out to eliminate the influence of non-specific motor problems. The results indicated that cerebral ischemia instigate the increase of striatal dopamine in I group rats during acute cerebral ischemia. A 3-week voluntary wheel running significantly enhances the striatal dopamine before ischemia and obstructs a further increase of dopamine during acute cerebral ischemia in 3RI group rats. At 24 hours after ischemia, striatal dopamine returned to pre-ischemic levels in 3RI group. Striatal dopamine in I group were less than pre-ischemic levels at 7 days. Behavioral data indicated that 3-week voluntary wheel running promoted recovery of anxiety-like behavior and gait were not affected by 2-VO cerebral ischemia at 24 hours post-ischemia rats. Therefore, it can be concluded that 3-week physical exercise significantly increased the striatal dopamine and improved anxiety-like behavior by inhibiting the increase of dopamine during acute cerebral ischemia and suppressing the decrease of dopamine after 24 hours and 7 days cerebral ischemia.