Miracle-dz/UniFAR-FTUs huggingface dataset:
Unmasking of a significant left main stenosis in a patient with high left ventricular pressures

As identification of left main (LM) stenoses has prognostic and therapeutic relevance, a precise anatomic and/or functional characterization of angiographically intermediate LM stenoses, by using intravascular ultrasound (IVUS) and fractional flow reserve (FFR) respectively, is crucial (1). However, increased left ventricular (LV) pressures might affect FFR measurements (2). Here we describe the case of a patient with chronic coronary syndrome and severe LV dysfunction in whom coronary angiography revealed an intermediate LM stenosis and catheterization identified an increased LV end‐diastolic pressure. FFR measurement showed disproportionally higher FFR values compared with the minimal luminal area assessed by IVUS. When cardiac output was artificially augmented by using Impella for assisting percutaneous coronary intervention, the value of FFR measurement turned out proportional to what expected for the degree of anatomical stenosis. This discrepancy between anatomic and functional measurement may be a sign of coronary autoregulation dysfunction and therefore could help to identify high‐risk patients in whom the use of a mechanical support device is more beneficial during percutaneous revascularization.
Patterns of discretionary food intake among Australian children and their association with socio‐demographic, lifestyle, and adiposity measures

Abstract Aim Australian children consume 35% of energy from discretionary food and beverages which increases their risk of non‐communicable diseases like type 2 diabetes. Despite this concerning statistic, broad analysis of the profile of discretionary food intake has not been fully undertaken. This study asks: what is the discretionary food and beverage intake profile, contribution to nutrient intakes, and associations with demographic and health characteristics? Methods Cross‐sectional data from the 2011–12 National Nutrition and Physical Activity Survey (n = 2812, 2–18 years) were used to profile discretionary food consumption. Dietary intake was assessed by 24‐h recall. General linear models tested the difference in respondent characteristics by age group, sex, and quartiles of discretionary food energy contribution. Results Ninety‐nine percent of respondents consumed discretionary foods, 74% exceeded the maximum discretionary food recommended serves. Among 10 eating occasions available to select: snack, dinner, lunch and morning tea appeared to contribute 76% of discretionary food energy, with snack and dinner contributing 24% each. Age and frequency of discretionary food consumption were positively associated with energy intake from discretionary foods (p < 0.001); while sex, socio‐economic status, physical activity and body composition had no association. High discretionary food consumers chose specific discretionary food items in a large quantity (1.0–3.5‐serves/discretionary food) compared to low discretionary food consumers (0.4–1.4‐serves/discretionary food). Conclusions Nearly all Australian children and adolescents consumed discretionary food daily. No demographic or anthropometric characteristics beyond increasing age were associated with higher discretionary food. Targeted public health policy and community interventions are required to focus on addressing the largest contributors to discretionary food intake in terms of equivalent serve sizes, popularity, and eating occasion.
Directional asymmetry and direction‐giving factors: Lessons from flowers with complex symmetry

Directional asymmetry is a systematic difference between the left and right sides for structures with bilateral symmetry or a systematic differentiation among repeated parts for complex symmetry. This study explores factors that produce directional asymmetry in the flower of Iris pumila, a structure with complex symmetry that makes it possible to investigate multiple such factors simultaneously. The shapes and sizes of three types of floral organs, the falls, standards, and style branches, were quantified using the methods of geometric morphometrics. For each flower, this study recorded the compass orientations of floral organs as well as their anatomical orientations relative to the two spathes subtending each flower. To characterize directional asymmetry at the whole‐flower level, differences in the average sizes and shapes according to compass orientation and relative orientation were computed, and the left–right asymmetry was also evaluated for each individual organ. No size or shape differences within flowers were found in relation to anatomical position; this may relate to the terminal position of flowers in Iris pumila, suggesting that there may be no adaxial–abaxial polarity, which is very prominent in many other taxa. There was clear directional asymmetry of shape in relation to compass orientation, presumably driven by a consistent environmental gradient such as solar irradiance. There was also clear directional asymmetry between left and right halves of every floral organ, most likely related to the arrangement of organs in the bud. These findings indicate that different factors are acting to produce directional asymmetry at different levels. In conventional analyses not recording flower orientations, these effects would be impossible to disentangle from each other and would probably be included as part of fluctuating asymmetry.
Effects of the short stitch technique for midline abdominal closure on incisional hernia (ESTOIH): randomized clinical trial

Abstract Background Incisional hernia remains a frequent problem after midline laparotomy. This study compared a short stitch to standard loop closure using an ultra-long-term absorbent elastic suture material. Methods A prospective, multicentre, parallel-group, double-blind, randomized, controlled superiority trial was designed for the elective setting. Adult patients were randomly assigned by computer-generated sequence to fascial closure using a short stitch (5 to 8 mm every 5 mm, USP 2-0, single thread HR 26 mm needle) or long stitch technique (10 mm every 10 mm, USP 1, double loop, HR 48 mm needle) with a poly-4-hydroxybutyrate-based suture material (Monomax®). Incisional hernia assessed by ultrasound 1 year after surgery was the primary outcome. Results The trial randomized 425 patients to short (n = 215) or long stitch technique (n = 210) of whom 414 (97.4 per cent) completed 1 year of follow-up. In the short stitch group, the fascia was closed with more stitches (46 (12 s.d.) versus 25 (7 s.d.); P < 0.001) and higher suture-to-wound length ratio (5.3 (2.2 s.d.) versus 4.0 (1.3 s.d.); P < 0.001). At 1 year, seven of 210 (3.3 per cent) patients in the short and 13 of 204 (6.4 per cent) patients in the long stitch group developed incisional hernia (odds ratio 1.97, 95 per cent confidence interval 0.77 to 5.05; P = 0.173). Conclusion The 1-year incisional hernia development was relatively low with clinical but not statistical difference between short and long stitches. Registration number: NCT01965249 (http://www.clinicaltrials.gov)
Weight Gain and Metabolic Syndrome in Human Immunodeficiency Virus Patients

While human immunodeficiency virus (HIV)-associated wasting has declined with significant advances in antiretroviral therapy (ART), weight gain and metabolic syndrome (MetS) are now becoming a problem for people living with HIV (PLWH) worldwide. The development of a new and more effective ART regimen has increased viral suppression and improved immunologic function recovery, leading to the extension of the lifespan of PLWH. It has recently been reported as one of the significant factors associated with weight gain, obesity, and long-term metabolic consequences in PLWH. This article reviewed the epidemiology of overweight and MetS among PLWH and the known risk factors for weight gain and its major comorbidities, such as dyslipidemia, diabetes mellitus, cardiovascular diseases, neurocognitive disorders, and liver diseases, in PLWH. In addition, reports on the pharmacological and surgical management of overweight and obesity in PLWH has been briefly summarized.
Spin–orbit configuration interaction study of spectral properties of PbO

Relativistic calculations of the structural and spectral properties of the PbO molecule can provide fundamental information about the importance of a proper treatment of angular momentum coupling among electrons in order to achieve accurate computational results for spectral properties. Specifically, the nature of these couplings in PbO is expected to be intermediate between the LS- and jj-coupling limits because of its light/heavy element composition. This article reports potential energy curves, transition energies, electric dipole transition moments, permanent dipole moments and spectroscopic constants of PbO calculated using a multireference single plus double excitations spin–orbit configuration interaction approach in the context of relativistic effective core potentials and their concomitant spin–orbit coupling operators. The calculated results are in general agreement with both available experimental results as well as earlier calculations. New values for properties of excited states are also reported. It is noteworthy that certain properties show larger deviations from previous calculations. These deviations are attributed to direct and indirect relativistic effects resulting from diatomic electron–electron angular momentum coupling effects, which are included consistently in the calculations reported herein.
Detection of arrhythmia in 12-lead varied-length ECG using multi-branch signal fusion network

Objective. Automatic detection of arrhythmia based on electrocardiogram (ECG) plays a critical role in early prevention and diagnosis of cardiovascular diseases. With the increase in widely available digital ECG data and the development of deep learning, multi-class arrhythmia classification based on automatic feature extraction of ECG has become increasingly attractive. However, the majority of studies cannot accept varied-length ECG signals and have limited performance in detecting multi-class arrhythmias. Approach. In this study, we propose a multi-branch signal fusion network (MBSF-Net) for multi-label classification of arrhythmia in 12-lead varied-length ECG. Our model utilizes the complementary power between different structures, which include Inception with depthwise separable convolution (DWS-Inception), spatial pyramid pooling (SPP) Layer, and multi-scale fusion Resnet (MSF-Resnet). The proposed method can extract features from each lead of 12-lead ECG recordings separately and then effectively fuse the features of each lead by integrating multiple convolution kernels with different receptive fields, which can achieve the information of complementation between different angles of the ECG signal. In particular, our model can accept 12-lead ECG signals of arbitrary length. Main results. The experimental results show that our model achieved an overall classification F1 score of 83.8% in the 12-lead ECG data of CPSC-2018. In addition, the F1 score of the MBSF-Net performed best among the MBF-Nets which are removed the SPP layer from MBSF-Net. In comparison with the latest ECG classification algorithms, the proposed model can be applied in varied-length signals and has an excellent performance, which not only can fully retain the integrity of the original signals, but also eliminates the cropping/padding signal beforehand when dealing with varied-length signal database. Significance. MBSF-Net provides an end-to-end multi-label classification model with outperfom performance, which allows detection of disease in varied-length signals without any additional cropping/padding. Moreover, our research is beneficial to the development of computer-aided diagnosis.
A 45‐ to 57‐GHz low‐power amplifier in 90 nm bulk CMOS

In this article, a novel two‐stage 45–57 GHz low‐power amplifier is presented and implemented in a 90‐nm bulk CMOS technology. The crossing‐capacitor neutralization technique is adopted to improve the gain and isolation of the amplifier. Meanwhile, the low‐loss transmission line and on‐chip transformer are designed for the matching networks. The measurement results show that the proposed amplifier achieves 3‐dB gain bandwidth of 12 GHz, from 45 to 57 GHz. The maximum small‐signal gain of this amplifier is 7.2 dB at 48.4 GHz, and the output 1‐dB compression power is −6.8 dBm at 48.4 GHz. This amplifier consumes total power of 5.52 mW under 1.2 V voltage supply.
Effects of prenatal methamphetamine exposure on spatial cognition and hippocampal synaptic plasticity in adolescent rats

Global rise in methamphetamine (MA) abuse during pregnancy has placed a large number of children at risk for the adverse consequences of prenatal methamphetamine exposure (PME). While behavioral and neurocognitive deficits of PME have been extensively studied in humans and adult rodents, far less is known regarding the sex‐ and dose‐dependent effects of PME as well as the underlying mechanisms. Adolescence in nonhuman primates is also a less explored territory. In the present study, PME was inducted by oral treatment to pregnant rats on gestational days 15–19 with either low dose (0.1 mg/ml) or high dose (0.6 mg/ml) of MA. The cognitive effects of PME were then evaluated in two adolescence age‐intervals: early adolescent (started on postnatal day [PND] 21) and mid‐adolescent (started on PND 33), among male and female rat offspring using Morris water maze (MWM) test. Alterations in hippocampal synaptic plasticity in Schaffer collaterals‐CA1 pathway were also measured in vitro. Results of behavioral test showed that PME led to serious deficits of learning and memory abilities in both male and female rat offspring. PME also depressed LTP in most of the PME subgroups. Moreover, 21‐day‐old rats were more sensitive to PME‐induced cognitive impairment in MWM tasks, but not in hippocampal synaptic plasticity, than 33‐day‐old rats. No sex‐dependent effects of PME were found on the cognitive function and synaptic plasticity. These findings confirmed that PME impacted negatively on cognitive performance in prepubertal male and female rats, and the impairment of hippocampal synaptic functions might partly play a significant role in these effects.
Factors Affecting Customer Satisfaction Of Retail Banking Services Of Commercial Banks

Received: April 01, 2021 Retail banking service has always been considered a core activity. It has the effect of speeding up the cash flow process, taking advantage of the great potential of the capital of all economic sectors. It is to lend to improve people’s living standards, limiting cash payments, and contributing to saving cost and time for both the banks and the customers. Besides, the development of retail banking services is in line with the inevitable trend in the operation of commercial banks in the region, in the world in general, and of Vietnamese commercial banks in particular. Therefore, the authors surveyed 750customersusing retail banking services. In addition, the articlefound out factors affecting customer satisfaction of retail banking services of commercial banks in Dong Nai provincewith one percent significance. The paper was applying structural equation modeling(SEM). Finally, the authorshadpolicy recommendations to enhancecustomer satisfaction of retail banking services of commercial banks. Accepted: September 01 , 2021
Fractal Properties of Etched Microcrystalline Silicon Surfaces

Real microcrystalline silicon is a mixture of small crystalline grains (also known as crystallites) and amorphous phase silicon. It is distinct from monocrystalline and amorphous silicon. Microcrystalline (more general polycrystalline) silicon is being used in large-area electronics and as a raw material by the solar photovoltaic industry (multicrystalline solar cells are the most common type of solar cells in the photovoltaic market). Solar cells prepared from this material are attractive for production cost and suitable solar cell efficiencies. Properties of formed solar cells are determined by the properties of device microstructure. The importance of the microstructure properties can be illustrated by the following example showing enormous complexity of the problem. For the intrinsic hydrogenated microcrystalline Si layers in solar cells, promising solar cell efficiencies were obtained at the transition from microcrystalline to amorphous growth [1]. This transition occurs in a very narrow range of silane-tohydrogen ratio in the process gas and depends on the surface morphology of the substrate. Near the transition from crystalline to amorphous growth the defect density of the intrinsic material decreases rapidly. An accompanying effect is the increase in the concentration of the silicon-hydrogen bonds [2-6]. Exact control of the microstructure during the deposition is therefore a crucial requirement.
Parallel Communicating Finite

A parallel communicating ﬁnite automata system is an accepting device based on the communication between more ﬁnite automata working in parallel. It consists of several automata working independently but communicating with each other by request. We survey several variants of parallel communicating ﬁnite automata systems with respect to their computational power. Other aspects like decidability and complexity matters are also brieﬂy discussed. Some open problems and directions for future research are ﬁnally pointed out.
Effects of Ribonucleotide Reductase Inhibition on Pyrimidine Deoxynucleotide Metabolism in Acyclovir-Treated Cells Infected with Herpes Sitnplex Virus Type 1

The pyrintidine metabolism of fibroblasts infected with herpes simplex virus type 1 was studied. Herpes simplex virus type 1 infection increased the dTTP pool and thymidylate synthetase activity but reduced thymidine excretion. Addition of acyclovir to infected cells increased thymidine excretion, the dTTP pool, and thymidylate synthetase activity. Addition of a virus-specific ribonucleotide reductase inhibitor (A723U) decreased all three. The synergy between the two compounds is discussed.
Storage-Class Memory Hierarchies for Servers

With emerging storage-class memory (SCM) nearing commercialization, there is evidence that it will deliver the much-anticipated high density and access latencies within only a few factors of DRAM. Nevertheless, the latency-sensitive nature of memory-resident services makes seamless integration of SCM in servers questionable. In this paper, we ask the question of how best to introduce SCM for such servers to improve overall performance/cost over existing DRAM-only architectures. We first show that even with the most optimistic latency projections for SCM, the higher memory access latency results in prohibitive performance degradation. However, we find that deployment of a modestly sized high-bandwidth 3D stacked DRAM cache makes the performance of an SCM-mostly memory system competitive. The high degree of spatial locality that memory-resident services exhibit not only simplifies the DRAM cache’s design as page-based, but also enables the amortization of increased SCM access latencies and the mitigation of SCM’s read/write latency disparity. We identify the set of memory hierarchy design parameters that plays a key role in the performance and cost of a memory system combining an SCM technology and a 3D stacked DRAM cache. We then introduce a methodology to drive provisioning for each of these design parameters under a target performance/cost goal. Finally, we use our methodology to derive concrete results for specific SCM technologies. With PCM as a case study, we show that a two bits/cell technology hits the performance/cost sweet spot, reducing the memory subsystem cost by 40% while keeping performance within 3% of the best performing DRAM-only system, whereas single-level and triple-level cell organizations are impractical for use as memory replacements. Permission to make digital or hard copies of all or part of this work for personal or classroom use is granted without fee provided that copies are not made or distributed for profit or commercial advantage and that copies bear this notice and the full citation on the first page. Copyrights for components of this work owned by others than ACM must be honored. Abstracting with credit is permitted. To copy otherwise, or republish, to post on servers or to redistribute to lists, requires prior specific permission and/or a fee. Request permissions from permissions@acm.org. MemSys’18, October 2018, Washington, DC, USA © 2018 Association for Computing Machinery. ACM ISBN 978-x-xxxx-xxxx-x/YY/MM. $15.00 https://doi.org/10.1145/nnnnnnn.nnnnnnn ACM Reference Format: Dmitrii Ustiugov, Alexandros Daglis, Javier Picorel, Mark Sutherland, Babak Falsafi, Edouard Bugnion, and Dionisios Pnevmatikos. 2018. Storage-Class Memory Hierarchies for Servers. In Proceedings of ACM Conference (MemSys’18). ACM, New York, NY, USA, 16 pages. https://doi.org/ 10.1145/nnnnnnn.nnnnnnn
Enabling Storage Class Memory as a DRAM Replacement for Datacenter Services

With emerging storage-class memory (SCM) nearing commercialization, there is evidence that it will deliver the much-anticipated high density and access latencies within only a few factors of DRAM. Nevertheless, the latency-sensitive nature of memory-resident services makes seamless integration of SCM in servers questionable. In this paper, we ask the question of how best to introduce SCM for such servers to improve overall performance/cost over existing DRAM-only architectures. We first show that even with the most optimistic latency projections for SCM, the higher memory access latency results in prohibitive performance degradation. However, we find that deployment of a modestly sized high-bandwidth 3D stacked DRAM cache makes the performance of an SCM-mostly memory system competitive. The high degree of spatial locality that memory-resident services exhibit not only simplifies the DRAM cache's design as page-based, but also enables the amortization of increased SCM access latencies and the mitigation of SCM's read/write latency disparity. We identify the set of memory hierarchy design parameters that plays a key role in the performance and cost of a memory system combining an SCM technology and a 3D stacked DRAM cache. We then introduce a methodology to drive provisioning for each of these design parameters under a target performance/cost goal. Finally, we use our methodology to derive concrete results for specific SCM technologies. With PCM as a case study, we show that a two bits/cell technology hits the performance/cost sweet spot, reducing the memory subsystem cost by 40% while keeping performance within 3% of the best performing DRAM-only system, whereas single-level and triple-level cell organizations are impractical for use as memory replacements.
Substitution-boxes based on Binary Tree built by Variants of Depth First Search

— In today’s age maximum communication takes place through internet and online channels. Therefore, securing of data has become even more vital and to fulfil this purpose data is encrypted in an unreadable form known as cryptography. S-box is established to obtain this purpose because it provides data obscurity, dependability and power to withstand against attacks from illegal resources. This paper shows the construction of resilient and robust S-boxes based on binary tree build by variants of Depth First Search. We tested our S-boxes using different analyses such as algebraic, statistical and also for image encryption.