Miracle-dz/UniFAR-FTUs huggingface dataset:
Multi-layered virtual transport network design and management (PhD Thesis)

Nowadays there is an increasing need for a general paradigm that can simplify network management and further enable network innovations. Software Defined Networking (SDN) is an efficient way to make the network programmable and reduce management complexity, however it is plagued with limitations inherited from the legacy Internet (TCP/IP) architecture. On the other hand, service overlay networks and virtual networks are widely used to overcome deficiencies of the Internet. However, most overlay/virtual networks are singlelayered and lack dynamic scope management. Furthermore, how to solve the joint problem of designing and mapping the overlay/virtual network requests for better application and network performance remains an understudied area. In this thesis, in response to limitations of current SDN management solutions and of the traditional single-layer overlay/virtual network design, we propose a recursive approach to enterprise network management, where network management is done through managing various Virtual Transport Networks (VTNs) over different scopes (i.e., regions of operation). Different from the traditional overlay/virtual network model which mainly focuses on routing/tunneling, our VTN approach provides communication service with explicit Quality-of-Service (QoS) support for applications via transport flows, i.e., it involves all mechanisms (e.g., addressing, routing, error and flow control, resource allocation) needed to meet application requirements. Our approach inherently provides a multi-layer solution for overlay/virtual network design. The contributions of this thesis are threefold: (1) we propose a novel VTN-based man-
A Cluster-First Route-Second Heuristic Approach to Solve Periodic Multi-Trip Vehicle Routing Problem

stated that the should provide better quality solution of despite requiring and more complex compared to route-first cluster-second (RFCS). trying Vehicle This paper discusses periodic vehicle routing problems that allow vehicles to travel on multiple trips in a single day. It is known as the Multi-Trip Periodic Vehicles (MTPVRP) Problem Route. Cluster-first route-second (CFRS) heuristics to solve MTPVRP was proposed in this study. In phase 1, customers were divided into clusters using the formulation of integer programming. Phase 2 determined the route of the cluster and verifies that the total journey time to visit the trips does not exceed the working hours of the vehicle. The implementation of the heuristic CFRS to solve the real problem faced by the LPG distributor shows that the procedure could provide a better routing solution.
TİP-1 DİABETES MELLİTUS TANILI ÇOCUKLARDA GLİSEMİK KONTROL DERECESİNE GÖRE SOL VENTRİKÜL FONKSİYONLARININ EKOKARDİYOGRAFİK OLARAK DEĞERLENDİRİLMESİ Echocardiographic Evaluation of Left Ventricular Functions According to the Degree of Glycemic Control in Children with Type-1 Diabetes

Aim: The aim of the study was the evaluation of the effects of glycemic control on cardiac functions in children and adolescents diagnosed with Type-1 Diabetes Mellitus (DM). Materials and Methods: Children with Diabetes type-1 were divided into two groups as moderate-controlled (MC) and poorly-controlled (PC) patients according to the glycemic control. The patients were evaluated in terms of conventional, 'pulsed' Doppler and tissue Doppler imaging (DDG) echocardiographic parameters for left ventricular systolic and diastolic function. Results: Thirty children were in the MC group, thirty children in the PC group and 30 in the control group. There were statistically significant differences between diabetic patients and control groups in terms of 'pulsed' and tissue Doppler echocardiographic parameters. Tissue Doppler parameters in the PC group showed, statistically significant elongation time of isovolumetric relaxation, isovolumetric contraction and significantly shortening time of ejection, as a result, a significant relationship was found between the left ventricle functions and metabolic control. Conclusion: Conventional and tissue Doppler echocardiography showed dysfunction of left ventricular function in children with type-1 DM. This study found that impairment of left ventricular diastolic functions may be directly related to glycemic control, and children with poor metabolic control have a higher risk of diabetic cardiomyopathy.
Three-dimensional electromagnetic field in a conductive cylinder at eddy-current frequencies

This contribution is relevant to non destructive evaluation at eddy-current frequencies, and it focuses upon the development and validation of means of calculation of the electromagnetic field in a conductive cylinder when a circular loop source is located outside the cylinder and is arbitrarily orientated. This is the first step of the modelling of the electromagnetic behaviour of a multi-layered cylinder possibly affected by various defects (loss of material, magnetic or conductive inclusions).
Single Exposure to Prolonged Sitting Prior to Exercise Does not Impact Athletic Performance

Background: The effects of sitting, and benefits of breaking up sitting time, have been extensively researched in regard to cardiometabolic dysregulation; however, the effect of long periods of not moving prior to athletic performance are unclear. Despite this, the belief that periods of intermittent light exercise to break up sitting prior to exercise performance persists. Objectives: To examine the effect of prolonged sitting time, as well as one common and one novel intervention to break up sitting, on subsequent exercise. Methods: 30 healthy individuals in ≥80 percentile of age and gender matched fitness participated in three conditions: 1) 5hr of uninterrupted sitting, 2) 5hr of interrupted sitting with 5 min walking bouts at 4.8 km/h every 30min, 3) 5hr of sitting with passive blood flow restriction and transcutaneous electrical muscle stimulation (BFR+TEMS) every 60min. A baseline assessment of maximal leg power generation and an incremental exercise protocol using a stationary cycle ergometer were conducted prior to the sitting protocol. Primary outcomes after 5hr of sitting included maximal leg power and time to exhaustion during incremental cycle ergometery to voluntary fatigue. Results: 5hr of uninterrupted sitting did not significantly alter leg power relative to baseline (Δ= -80± 998 W), nor did BFR+TEMS (Δ= 7 ±1252 W), or WALK (Δ= 53± 547 W) interventions (all p>0.05). Prolonged sitting was not detrimental to time to exhaustion (Δ= 10 sec 95% CI -7 sec, 27 sec). Analysis of the BFR+TEMS (Δ= 23 sec, 95% CI -74 sec, 28 sec) and WALK (Δ= 14 sec, 95% CI -90 sec, 62 sec) groups, compared to corresponding controls, indicated that there were no additional ergogenic effects of either intervention strategy. Conclusions: Considering explosive leg power and aerobic cycling to exhaustion, uninterrupted sitting for 5 hours prior to exercise had no negative effect on performance, and neither intermittent walking nor blood flow restriction with electrical stimulation further improved performance.
Carbon isotopic compositions of individual long-chain and n-alkanes in sediments from river to open Multiple origins for their occurrence n-fatty ocean: acids

Stable carbon isotopic compositions of individual n-fatty acids and n-alkanes were determined in six sediments from the Ohtsuchi River to the Pacific Ocean at north Honshu Island, Japan. Long-chain n-fatty acids (LCFAs) ranging from C20 to C30 and long-chain n-alkanes (LCALs) ranging from C23 to C33 have large isotopic variations from -35 to -25%o and -35 to -29%o, respectively, although the molecular distri butions of LCFAs and LCALs are almost identical in all analyzed samples. LCFAs are more depleted in 13C than total organic carbon (TOC) by about 5 to 12%o. The 613C values are relatively similar between n-C20 and n-C26, and gradually decrease with increasing molecular weight to n-C30 by 3 to 5%0. Each n-fatty acid component shows a systematic enrichment in 13C from river to open ocean by up to 6% (from -32.5 to -26%o for n-C26), and a similar isotopic composition in the open ocean (--26%o for n-C26). LCALs are also more depleted in 13C than TOC by about 6 to 12%o. The S13C values gradually decrease from n-C19 to n-C31 by up to 6%0, then increase for >n-C31. Abundant LCALs, such as n-C29 and n-C31, show a systematic enrichment in 13C from river to open ocean by up to 3% (from -34.6 to -31.9%o for n-C31), and a similar isotopic composition in the open ocean (--31.5%o for n-C31). On the other hand, C35 n-alkane has a relatively uniform isotopic composition (--29%) for all sediments. Such isotopic variations exhibit good correlations with 613CTOC (-26.4 to -20.4%o) and C/N ratio (12 to 7 by atom) variations as well as amount of sedimentary cutin and lignin-derived organic compounds of terrestrial higher plant origin. The isotopic distributions can be explained by a two-component mixture model involving isotopically different terrestrial and marine LCFAs and LCALs as endmember components. Although LCFAs (>n-C20) and LCALs (>n-C23) in marine sediments have been previously presumed to be derived from terrestrial higher plants, the results presented here may indicate that some of the LCFAs and LCALs in marine sediments are actually originated in the marine environment. Compound-specific isotope signature is im portant for evaluating the sources, as well as transport and mixing processes for the LCFAs and LCALs in a terrestrial-marine system.
Poverty , Dickens ’ s Oliver Twist , and

As the precursor to the science of economics, political economy concerned some topics that also preoccupied novelists, such as poverty and wealth. Literary criticism in the late twentieth and early twenty-first centuries has been charting the ways in which the discourses of literature and political economy intersect, despite the Romantic disavowal of their commonalities. Aiming to contribute to this ongoing scholarly effort, this essay pinpoints an unexpected affinity between Charles Dickens’s Oliver Twist, a novel which addresses the plight of the poor under the New Poor Law of 1834, and the political economist J. R. McCulloch’s writing on that piece of legislation. Both mistrust theoretical knowledge and privilege the particular as the basis on which one must make decisions. This affinity is unexpected because Oliver Twist repudiates political economy. Recognizing McCulloch’s and Dickens’s common epistemology alerts us to the ways in which the preference for the particular over the systemic shapes Oliver Twist. The common ground between Oliver Twist and McCulloch’s writing on the New Poor Law attests to the interconnectedness of literature and political economy.
Process model for systematic requirements prioritisation process in an agile software development environment based on 5S approach: Empirical study

In an unstable software development characterized by the turbulence of markets and the competitive pressures, the organization is forced to adopt new software development methodology to be survival. The agile methods have been introduced to maintain the organization endurance. New challenges await agile methods, when requirement prioritisation and re-prioritisation happened frequently, this leads to unstable and disorganize requirement prioritisation process in agile development environment. To improve its effectiveness and make the environment more systematic and organized, this study proposes an adoption of the lean manufacturing tool, which is 5S approach. The 5S approach improve the work environment as it’s designed to check the process and guaranty that issues are identified and get rid of issues. Consequently, this study aims to identify the issues that affect the requirement prioritisation process. Therefore, in-depth interviews have been carried by involving 18 agile practitioners from different agile software development companies. The data collected for this study were analyzed by using grounded theory techniques (Open, Axial and Selective coding). The results are proposed a process model that will allow an improvement of the process by applying a suitable “S” to overcome the issues that might lead to unsystematic and disorganize environment.
Board 8: Identifying At-Risk Students in a Basic Electric Circuits Course Using Instruments to Probe Students' Conceptual Understanding

Electric circuit analysis is a gateway course for students in the electrical and computer engineering disciplines. Such courses build upon a foundation developed in the first weeks of class, making student success heavily dependent upon a strong command of this initial material. Therefore, it is paramount to identify struggling students early. This has prompted the search for instruments that can reliably identify at-risk students within the first week of class, as it is believed that this will afford sufficient time to provide the necessary assistance for at-risk students to succeed. For the purposes of this research, at-risk students are those identified as likely to receive a D, F, or to withdraw from the course. This paper examines the use of various tools to help identify at-risk students in an introductory course in circuit analysis. Based on initial analysis, it is speculated that early activities that promote basic metacognitive skill development and the construction of proper mental models are critical to promoting success in the typical circuit analysis course. The features described provide a model for delivering meaningful assistance to at-risk students in such courses.
The Development Model of Active Learning for English Chemistry and Model Effectiveness

This manuscript is a part of The Development Model of Active Learning for English Chemistry has been conducted. The English for Chemistry Course materials worksheet for chemistry education students- FKP- Riau University aims at not only supporting student work study programs but also supporting their professional Chemistry teacher candidates later on. So in order to increase of the mastery of content, this student’s worksheet is developed and provided for them. Development of methods of teaching materials/course worksheet (or also called LKM in Indonesia) is adopted the Plomp’s design which consists of three stages: the initial study or sometimes called preliminary study (analysis of the needs and characteristics of learners), product (prototype) and evaluation (validation product). After the prototype teaching materials forming which is based on student needs and their characteristics, then the product is validated until the expert perceived the product is fulfill the standard quality. The product is validated by instructional design specialist, expert specialist content (chemical education) and English language experts. All of inputs and comments will be based to formulated a new next protipe. In this stage of research report, the validation of product protoype conducted just until self-evaluation or/first product evaluated. The Final model is being assesed by student evaluaton test.
TECHNOLOGICAL TOOLS TO INCLUDE WHEY PROTEINS IN CHEESE : CURRENT STATUS 2 AND PERSPECTIVES 3 4

Background: Cheese manufacturing consists of a dehydration process by which most of the whey is drained off. Whey proteins (WP) represent a nutritionally valuable fraction largely lost in the whey stream. The increasing consumer demand for food with novel texture and functionality prompted the dairy industry to exploit the valorization of WP. Scope and approach: Cheese milk is considered a vehicle for the inclusion of WP. In this review, we discuss technological tools to fortify cheese with WP. We focus on both the pioneer approaches (the heat treatment of cheese milk, membrane separation technologies and the direct addition of milkor whey-based derivatives) and on more recent techniques such as high hydrostatic pressure, ultra-high pressure homogenization, transglutaminase treatment of cheese milk and direct addition of buttermilk. Key findings and conclusions: Milk fortification with WP influences the yield and overall properties of resulting cheeses. Processing conditions need to be adapted to successfully manufacture WP-fortified conventional cheeses as well as novel varieties (such as low-fat cheeses). As yet, only some technological tools to include WP in cheese are exploited at industrial scale. The combination of different techniques is a strategy to overcome the impairment of cheese attributes.
FACTORS AFFECTING THE PERFORMANCE OF ICT SOFTWARE PROJECT MANAGEMENT: CASE STUDY OF COMPULYNX LIMITED

In the last few years, the project management discipline has matured through the publication of several standards best practices research articles and significant growth in its community of professional From this, it may be concluded that today, the majority of projects are completed successfully. However, literature suggests that this is not the case, especially in the information and communication technology (ICT) environment. The objective of this study is to assess the factors contributing to poor performance of ICT Software project management. The study shall target the ICT Software development management team members (Project Managers, project Designers, developers, Testing team and intergrators) depending on the project team structure for Compulynx Limited.The study adopted descriptive research design since the researcher sought to gather information, summarize, present and interpret it for the purpose of clarification. The study targeted 500 employees of Compulynx Limited in Nairobi. Questionnaires were used to collect data for this study. Statistical package for social science (SPSS) was used to analyse data.The findings were presented inform of tables and charts. The four independent variables that were studied, explain 88.1% of the factor affecting ICT software projects performance as represented by the R 2 . Therefore, a further research should be conducted to investigate the other factors (19.9%) that affects ICT software projects performance in Kenya.The study found that majority of the respondents agreed that Project management practices, Top Management support, user involvement and Project Monitoring influence ICT software project performance.
Prioritizing cost management system considerations for Nigerian housing projects

Purpose This study aims to develop a success factor model to understand and facilitate improved cost management system (CMS) implementation in low-cost housing (LcH) project delivery in Nigeria. Design/methodology/approach Literature findings highlight 13 drivers affecting effective implementation within the CMS and uses series of brainstorming sessions and questionnaire surveys to validate the drivers. Factor analysis (FA) identifies possible contextual relationships among the validated drivers and groups them into three success factors. The results of the FA are refined using interpretive structural modelling (ISM). The ISM identifies and models the influential drivers and aids the development of the success factor model. Findings Effective team qualities, information and management actions and a stable operational environment are the three essential success factors for effective CMS implementation. Practical implications The paper highlights effective team qualities as the most important CMS considerations for Nigerian LcH project delivery. This finding creates the needed awareness to guide project sponsors and project managers in the appropriate selection of the project management team (PMT) as well as the procurement system that facilitates their collaboration. Originality/value This study is a novel research using FA and ISM to investigate the influence of success factors needful for effective implementation within the CMS. It further develops a hierarchy model that aids the PMT with better understanding of the drivers and factors interrelationships for use on LcH projects within the Nigerian context.
Joana Catarina Pereira Guedes Molecular Mechanisms Underlying the Anticancer Activity of Lactoferrin in Highly Metastatic Cancer Cell Lines

Cancer is currently one the most lethal disease worldwide and metastases remain the main cause of cancer-associated mortality, which reinforces the importance of developing more targeted and efficient cancer therapies. In this sense, lactoferrin (Lf) has emerged as a safe and effective agent in cancer therapy. Lf is a natural iron-binding protein derived from milk that is present in many tissues and biological fluids. Interestingly, it was found that Lf displays anticancer and anti-metastatic activities against several cancer cell lines. However, Lf cellular targets implicated in its mechanisms of action are poorly elucidated, which limits the usage of Lf in cancer therapy. Hence, unveiling the targets of Lf underlying its anticancer activity is of prime relevance and it will be explored in the current work. Recently, results of our group showed that bovine Lf (bLf) is preferentially cytotoxic to highly metastatic breast cancer cells through inhibition of the plasmalemmal proton pump V-ATPase, while exhibiting no effect on non-tumorigenic cells. In the present study, we aim to ascertain whether this same mechanism of action could explain the anticancer/anti-metastatic activity of bLf against other types of highly metastatic cancer cells. To this end, three highly metastatic cancer cell lines, reported to display V-ATPase at the plasma membrane, were used: PC-3, MG-63 and MDA-MB-231, prostate, osteosarcoma and breast cancer cell lines, respectively. Results showed that the susceptibility to bLf of PC-3 and MG63 cancer cell lines was similar to that of the breast cancer MDA-MB-231 regarding both inhibition of cell proliferation and induction of intracellular acidification. Moreover, we found that V-ATPase expression seemingly increased in the three cell lines in comparison to a non-tumorigenic cell line. These data encouraged us to implement several biochemical and analytical approaches, including flow cytometry, western blot, immunofluorescence and confocal microscopy in order to dissect the possible interplay between V-ATPase and bLf in these cell lines. Overall, the results herein obtained may be further explored to develop new cancer therapy strategies against highly metastatic cancers.
Wideband unequal filtering power divider with high power dividing ratio based on line ‐ inserted method

In this study, a type of wideband ‐ filtering power divider (FPD) with high power dividing ratio (PDR) is proposed based on the line ‐ inserted method. The proposed wideband FPD is implemented by inserting a quarter ‐ wave line in front of the conventional wideband FPD. With the inserted line acting as part of each filtering branch, an additional in ‐ band pole is generated, and the requirement for high input impedance can be relaxed. Consequently, both the fractional bandwidth (FBW) and maximum PDR can be enhanced. To enforce the effectiveness of the inserted line, a corresponding design method for the wideband FPD is proposed and demonstrated. Initially, a wideband filter involving the inserted line is synthesized. Then, the synthesized filter is used for implementing wideband FPD using voltage transformers. Finally, the voltage transformers are successfully absorbed into the filtering branches. Examples of 4:1 and 12:1 FPDs operating at 1.8 GHz are designed and fabricated with specified FBWs of 100% and 88%. The measured PDRs are 3.9:1 and 11.2:1 with corresponding bandwidths of 103.9% and 88.3% (| S 11 | < –10 dB), respectively. The proposed wideband FPD exhibits a higher PDR, wider bandwidth, equal ‐ ripple response, and filtering embedded compared with the conventional ones.