Miracle-dz/UniFAR-FTUs huggingface dataset:
ASSESSMENT OF CLINICAL UTILITY OF GRAY SCALE RENAL ULTRASOUND IN ACUTE KIDNEY INJURY

Background: To assess clinical utility of gray scale renal ultrasound in acute kidney injury. Materials and Methods: One hundred ten acute kidney injury (AKI) patients of both genders were divided into 2 groups. Group I had AKI patients and group II had healthy subjects. Parameters such as etiologies of AKI, the highest serum creatinine levels in AKI, and serum creatinine levels after therapy were collected. Renal ultrasonography (US) was performed with an Evolution E10 scanner using a 3.5–5.0 MHz wide-frequency band. The US was assessed for kidney size (the length, width, and thickness of each kidney), the thickness of the renal parenchyma, parenchymal echogenicity, RRI, and other abnormalities. Result: The mean serum creatinine in group I and group II was 314.5 μmol/L and 86.2 μmol/L. Length of left kidney was 108.2 mm and 105.3 mm, width of left kidney was 57.4 mm and 50.1 mm, thickness of left kidney was 47.6 mm and 40.2 mm, volume of left kidney was 145.3 cm3 and 114.7 cm3, thickness of left parenchyma was 16.9 and 16.1 respectively. Length of right kidney was 107.5 mm and 102.9 mm, width of right kidney was 56.2 mm and 48.0 mm, thickness of right kidney was 46.5 mm and 43.2 mm, volume of right kidney was 142.6 cm3and 109.8 cm3 and thickness of right parenchyma was 15.8 and 15.1 respectively. Etiology of AKI was heart failure in 20 patients, volume depletion in 24, glomerular diseases in 35, ATN in 6, sepsis in 5, obstructive nephropathy in 4, oncolytic syndrome in 3, acute leukemia in 5, severe pancreatitis in 4, and CKD with drug induced renal damage in 4. The difference was significant (P< 0.05). Conclusion: Gray scale ultrasound found to be effective in assessment of cases of acute kidney injury.
Toward a Theory of Coherent Synchrotron Radiation in Realistic Vacuum Chambers

An idealized theory predicts coherent synchrotron radiation (CSR) in whispering gallery modes, in quantitative agreement with observations at NSLS-VUV in 2001. A quantitative comparison to theory was difficult for later experiments at the CLS (Canadian Light Source) owing to the complicated form of the vacuum chamber at the point of observation. Efforts to improve the theory led to a general scheme for studying fields in a rectangular chamber of varying width. It works in the frequency domain, with a spatial Fourier development only in the vertical coordinate. The calculation reduces to integration of a simple system of ordinary differential equations, with arc length s as the independent variable. A new scheme to handle a transversely singular or highly concentrated charge/current is an essential feature. If the equations are integrated by an implicit rule (trapezoidal method) the calculation can be speeded up by a large factor in comparison to explicit integration, and the paraxial approximation can be avoided, thus accommodating backward-propagating waves. The time for the field calculation is so short that it will be negligible compared to that for charge/current construction and particle pushing in a self-consistent macroparticle simulation, which could be in three dimensions.
Automated detection of airfield pavement damages: an efficient light-weight algorithm

ABSTRACT Fast and accurate detection of airfield pavement damage is crucial to airport flight safety and airfield pavement maintenance. An efficient and lightweight detection algorithm that can be embedded into the mobile detection device has been in urgent demand. However, traditional Convolutional Neural Networks (CNNs) usually generate redundant feature maps during feature extraction or use extra operations during feature fusion to gain better performance, which greatly challenges the efficiency of the algorithm. We approached this issue by proposing an accurate and efficient detection algorithm, the YOLOv5-APD. The algorithm improves the model performance in two ways: Speeding up training and inferencing by using cheaper operations during feature extraction; Reducing the model complexity by removing redundant nodes during feature fusion. We verified the detection performance of YOLOv5-APD on a self-made dataset and compared it with the other state-of-the-art (SOTA) models. Then ablation experiments were carried out to investigate the effects of the proposed model design and the impact of image augmentation. Results showed that the proposed YOLOv5-APD model outperformed the SOTA algorithms in model performance and efficiency, which attained the optimal performance mean average precision (mAP) of 0.924. The proposed model also achieved the fastest inference speed of 142 frame-per-second (FPS), with a model footprint of 8.3 G FLOPs and 8 MB Parameters.
COMPARATIVE AGE FEATURES OF CLINIC AND PATHOGENETIC ASPECTS OF SCHOOL DISADAPTATION

Intensive processes of maturation of certain biological systems of the body in conjunction with an increase in the level of socio-psychological requirements for students, increase the possibility of psihotrauvmatik personality. The clinic manifestations and the main factors of pathogenesis of school disadaptation in the comparative-age aspect (7-11 years old, n = 950) and (12-17 years old, n = 550). More significant factors of risk together with the psycho - social ones (conditions of micro social sphere of family and school) are genetic and cerebral organic. The feature of found out by children and teenagers disadaptation is its massive somatisation, which charactrised by polymorph vegetative and visceral disorders in different organs and systems (digestive, skin, respiratory, moving, heart-vessel,secretory,endocrine) and paintful manifestation. Results. Thus, clinical and population-based studies conducted amonghealthy schoolchildren, revealed a greater incidence of children and adolescents with adjustment disorders (72%), among which is dominated by Grade III - a relative maladjustment. The most significant risk factors, along with psycho-social (micro social status of the family and school environment) are genetic and cerebro-organic. A feature of the identified children and adolescents maladjustment was its massive somatic, which was characterized by polymorphic vegetative-visceral disorders in various organs and systems (digestive, skin, respiratory, locomotor, cardiovascular, excretory, endocrine) and algic manifestations.
Use of patient‐derived tumor organoid platform to predict the benefit of postoperative adjuvant chemotherapy for poor responders to neoadjuvant chemoradiotherapy in locally advanced rectal cancer

Abstract Postoperative adjuvant chemotherapy (AC) for poor responders to neoadjuvant chemoradiotherapy (nCRT) remains debatable among patients with locally advanced rectal cancer (LARC), necessitating biomarkers to accurately predict the benefits of AC. This study aimed to develop a patient‐derived tumor organoid (PDTO) platform to predict the benefit of AC in LARC patients showing poor nCRT response. PDTOs were established using irradiated rectal cancer specimens with poor nCRT responses, and their sensitivity to chemotherapy regimens was tested. The half‐maximal inhibitory concentration (IC50) value for the PDTO drug test was defined based on the clinical outcomes, and the accuracy of the PDTO prognostic predictions was calculated. Predictive models were developed and validated using the PDTO drug test results. Between October 2018 and December 2021, 86 PDTOs were successfully constructed from 138 specimens (success rate 62.3%). The optimal IC50 cut‐off value for the organoid drug test was 39.31 μmol/L, with a sensitivity of 84.75%, a specificity of 85.19%, and an accuracy of 84.88%. Multivariate Cox regression analysis revealed that the PDTO drug test was an independent predictor of prognosis. A nomogram based on the PDTO drug test was developed, showing good prognostic ability in predicting the 2‐year and 3‐year disease‐free survivals (AUC of 0.826 [95% CI, 0.721–0.931] and 0.902 [95% CI, 0.823–0.982], respectively) and overall survivals (AUC of 0.859 [95% CI, 0.745–0.973] and 0.885 [95% CI, 0.792–0.978], respectively). The PDTO drug test can predict the benefit of postoperative AC in poor responders with LARC to nCRT.
URBAN PERCEPTIONS OF NATIONAL FORESTS: THREE EXAMPLES FROM THE NORTHERN UNITED STATES

A study of the perceptions of the management and use of proximate National Forests by residents of the Boston, Detroit, and Minneapolis Metropolitan areas was conducted in 2000. Respondents were contacted by telephone and surveyed about their perceptions of the management and use of nearby National Forests. These include the Green Mountain and White Mountain National Forests for Boston; the Huron-Manistee, Ottawa, and Hiawatha National Forests for Detroit; and the Chippewa and Superior National Forests for Minneapolis. A total of 600 interviews were completed for each Metropolitan area using computer assisted interviewing and up to 10 calls to each number, resulting in a response rate of 72 percent. Responses included the personal importance that individuals placed on the National Forests, including benefits, attributes, their use of the Forests, and the importance they attached to goals for National Forest management and particular management practices. Results have implications for managers of public lands who are working to build a constituency among the residents of major Metropolitan areas within a half-day drive of the Forest. The study also provides information that can help guide research aimed at supporting urban outreach efforts.
Impact of Somatic Cell Count on Milk Yield, Milk Composition, and Growth Performance in Zaraibi Goats During Different Physiological Stages of Lactation Period

: The study investigated the effect of different somatic cell count (SCC) classes on milk production traits and growth of Zaraibi does and kids at three distinct physiological stages during lactation. A total of 150 milk samples obtained from 50 goats at milk peak, kids weaning, and meeting periods (days of 50, 100 and 150) were analyzed. The goats were selected based on strict criteria, including the same age, kidding date, low milk SCC, and no udder problems. The goats were divided into three classes based on overall milk SCC values: SCG1 (≤315x10 3 cells/mL), SCG2 (316-335x10 3 cells/mL), and SCG3 (>335 x10 3 cells/mL). The results showed that although there were significant differences between SCC1 and SCC2 classes in SCC and log SCC at different stages of lactation, there were no significant differences in milk production and composition. The daily milk yield decreased significantly with increased SCC level (> 335x10 3 cells/mL), and the highest milk losses were observed. The milk composition followed the same pattern of significant differences among SCC classes during different lactation stages, with the highest values observed in the highest SCC class (> 335x10 3 cells/mL). The daily milk yield decreased gradually with increasing lactation stage, while SCC values increased gradually. The does’ body weight did not change significantly by lactation stage. Overall, the findings suggest that SCC level of > 335x10 3 cells/mL has a significant effect on milk production and composition, but not on growth traits of Zaraibi does’ and kids during different stages of lactation. These findings could be useful for dairy farmers to manage their herds and optimize milk production to produce high-quality dairy products.
Herbivore enamel carbon and oxygen isotopes demonstrate both Homo sapiens and Neanderthals exploited similar habitats in the Zagros Mountains

The extinction of Neanderthal populations has been attributed to the onset of cold and dry climatic conditions during Marine Isotope Stage 3 or their competition with anatomically modern humans for large game resources. However, decoupling climate from competition has long proved difficult. Loess sequences and pollen cores provide regional‐scale environmental information but are less well‐suited to providing local‐scale habitat information contemporaneous with hominin habitation of occupation sites. The relationship between climate and resource availability is particularly unknown in the Zagros mountain range where archaeological evidence for both Neanderthals and Homo sapiens occupation is documented. Here, we analyse carbon (δ13C) and oxygen (δ18O) stable isotopes measured from herbivore tooth enamel carbonates recovered from the Neanderthal and modern human occupation sites of Bawa Yawan Rockshelter and Shanidar Cave to trace local‐scale floral biome dynamics and climate conditions that influence the distribution and availability of large prey targeted by both hominin species. Shared isotopic composition of herbivorous fauna, largely represented by wild goats, from both sites spanning Neanderthal and Homo sapiens occupation indicate both hominin species exploited similar habitats during climatically similar phases.
The impact of additive manufacturing on teaching the Archimedes experiment

This study aimed to investigate the effectiveness of additive manufacturing (AM)-based teaching methods compared to traditional methods for teaching the Archimedes experiment in science education. Results showed that the AM method was significantly more effective in enhancing students’ understanding of the Archimedes principle and their ability to apply it to real world scenarios. The customisable and hands on nature of 3D printing also led to higher levels of student engagement and enjoyment. However, limitations were identified in terms of the time, resources, and cost required to set up the 3D printing experiment. Despite these limitations, our study suggests that AM has the potential to revolutionise science education by providing students with a more engaging, hands on, and customisable learning experience.
Contribution à l'étude dynamique et fonctionnelle des peuplements de sables fins du golfe Normano-Breton

L'evaluation du role des facteurs ecologiques dans l'etablissement et le maintien des populations est indispensable a la comprehension du fonctionnement des ecosystemes. On distingue couramment les parametres physico-chimiques regroupes sous le terme abiotiques , de ceux directement lies aux activites diverses des etres vivants constitutifs du peuplement appeles Biotiques (PERES, 1976). Or, si certaines communautes sont soumises a l'action equilibree de ces deux categories de facteurs, d'autres sont dominees par l'une d'entre elles. Dans le golfe normano-breton, les effets globaux des facteurs abiotiques ont ete largement decrits par RETIERE (1979) qui a conclu au role primordial joue par l'edaphisme et plus particulierement la texture du sediment dans la composition de la plupart des peuplements benthiques. Il differencie plusieurs groupements faunistiques lies respectivement aux cailloutis, aux sediments grossiers sabla-graveleux, aux sables moyens et fins propres et aux sediments fins plus ou moins envases. Au sein meme des sediments les plus fins, deux unites cenotiques sont soumises a des conditions hydrodynamiques nettement tranchees : - le peuplement des sables fins a moyens propres a Donax variegatus - Armandia polyophthalma expose a l'action de la houle et aux forts courants de maree le long de la peninsule du Cotentin ; - le facies des sables fins envases a Melinna palmata du bassin de la Rance protege de la houle par le barrage.
A PROSPECTIVE OBSERVATIONAL STUDY COMPARING CONVENTIONAL MACINTOSH LARYNGOSCOPE WITH MCGRATH VIDEO LARYNGOSCOPE FOR COMPARING THEIR HEMODYNAMIC RESPONSE TO ENDOTRACHEAL INTUBATION

Background: McGrath video laryngoscope is claimed to be better than conventional Macintosh laryngoscope in terms of hemodynamic profile during endotracheal intubation. The prevention of aggravated sympathoadrenal response provoked by laryngoscopy and endotracheal intubation is an important issue for anaesthesia practice. This prospective observational study was done to compare the hemodynamic changes using Conventional Macintosh Laryngoscope and McGrath Video Laryngoscope during endotracheal Intubation. Materials and Methods: About 500 patients were observed in this study aged between 18-65 years of age of either sex with American Society of Anesthesiologists (ASA I-II) status, requiring general anesthesia for various surgical procedures who required endotracheal intubation. These patients were categorized into two groups: 1. Group CL (conventional Macintosh laryngoscope): Included patients where conventional laryngoscope was used. 347 patients were observed in this group. 2. Group MG (McGrath MAC videolaryngoscope): Included patients where McGrath MAC videolaryngoscope was used. A total of 153 patients were observed in this group. A standard anaesthesia technique was used in all the selected patients with entropy monitoring for depth of anesthesia. Intubation time, number of intubation attempts, need for stylet, additional manipulation, glottic view (Cormack-Lehane) and traumatic complications caused by intubation procedure and occurrence of sore throat postoperatively were also studied. Hemodynamic variables (HR,SBP,DBP) at baseline and following induction were also statistically compared in this study. The recorded data was compiled and entered in a spreadsheet (Microsoft Excel) and then exported to data editor of SPSS Version 20.0 (SPSS Inc., Chicago, Illinois, USA). Result: The parameters studied were hemodynamic parameters (HR, SBP, DBP) cormak-lehane grade, intubation time, number of intubation attempts, additional manipulation, traumatic complication and postoperative sore throat.
Chronic Suppurative Otitis Media: A Comprehensive Review of Epidemiology, Pathogenesis, Microbiology, and Complications

Otitis media is a significant contributor to healthcare visits and the prescription of drugs. Its associated complications and consequences pose the primary factors for preventable hearing impairment, especially in developing nations. Chronic suppurative otitis media (CSOM) is prevalent among children globally as one of the commonest chronic infectious diseases during childhood. The subsequent complications and sequelae play a central role in causing avoidable hearing loss, particularly within developing countries. In addition to impaired hearing, this condition can lead to severe health complications, such as issues involving the intracranial region. Despite the involvement of microbial, immunological, and genetic factors as well as Eustachian tube characteristics, in the development of CSOM, there remains a need for further elucidation regarding its pathogenesis. Based on its microorganisms, the treatment of choice will be affected to prevent further complications in the child. The primary approach to treating acute otitis media (AOM) involves effectively addressing ear pain and fever symptoms, while antibiotics are only administered in cases where children experience severe, long-lasting, or frequent infections. Despite the extensive investigation on AOM pathogenesis, research is scarce regarding CSOM. Given that antibiotic resistance and drug-induced ear damage are growing problems and surgery-related complications, it is imperative to devise effective therapeutic interventions against CSOM arises. Therefore, comprehending the host's immune function concerning CSOM and identifying how bacteria sidestep these potent responses becomes crucial. Acquiring insight into molecular mechanisms associated with CSOM will enable scientists to formulate innovative treatment approaches to combat this disease, thereby averting hearing loss consequences. The management consists of watchful waiting, primarily for children with chronic effusions and hearing loss.
The Distinct Effects of Information Technology and Communication Technology on Firm Organization

G by theories of “management by exception,” we study the impact of information and communication technology on worker and plant manager autonomy and span of control. The theory suggests that information technology is a decentralizing force, whereas communication technology is a centralizing force. Using a new data set of American and European manufacturing firms, we find indeed that better information technologies (enterprise resource planning (ERP) for plant managers and computer-assisted design/computer-assisted manufacturing for production workers) are associated with more autonomy and a wider span of control, whereas technologies that improve communication (like data intranets) decrease autonomy for workers and plant managers. Using instrumental variables (distance from ERP’s place of origin and heterogeneous telecommunication costs arising from regulation) strengthens our results. Data, as supplemental material, are available at http://dx.doi. org/10.1287/mnsc.2014. 2013.
Domus mobile: proposta de uma nova plataforma de suporte ao mobile-learning

Este artigo aborda o desenvolvimento da Intranet Domus, que integra tecnologias de e-learning e de emanagement, tornando mais eficientes os processos de ensino, aprendizagem e gestão administrativa. Com a definição da estratégia de integração dos vários sistemas numa única plataforma, conseguiu-se uma adesão muito significativa por parte dos docentes e alunos. A segunda fase do projecto, que se encontra em desenvolvimento, consiste em tornar a plataforma compatível com o SCORM e desenvolver objectos de aprendizagem reutilizáveis. Sendo definida uma nova framework que irá suportar o mobilelearning, disponibilizando uma interface para dispositivos móveis e permitindo também a aprendizagem em modo offline através da transferência de um pacote de sincronização. O objectivo desta nova plataforma é de permitir a ubiquidade da aprendizagem e do acesso à informação e ao conhecimento, independentemente do dispositivo, do local e da existência ou não de acesso à Internet.
Acute Responses Of A Drop-Set Session On Muscular Activation And Its Applicability In Resistance- Trained Individuals

We investigated whether performing repetitions to muscular failure (FAIL) during a drop-set would affect muscle activation in trained individuals. Twelve young men performed a drop-set session consisting of 3 sets of two intensity drops (80 to 60 and to 40% of one-repetition maximum [1-RM]) load in a leg press machine. Linear regression between the quadriceps femoris root mean square of surface electromyography (EMGRMS) was employed to observe the initial muscle activation (intercept) and its behavior over the repetitions (slope). The EMGRMS intercept of the first set decreased (p<0.05) according to load reduction (136.8±4.8 at 80%1-RM to 119.3±5.5 and 110.6±5.5 at 60 and 40%1-RM, respectively). Slopes different from zero (p<0.05) were observed at 80 and 60%1-RM during the first set. Remarkably, during the second and third sets, we observed an increased EMGRMS intercept at 60%1-RM (p<0.05), leading to non-significant (p>0.05) differences compared to 80%1-RM. The maximum initial muscle activation occurred at higher loads only, but low loads performed to FAIL may be necessary for increasing and maintaining muscle activation at higher loads. Understanding these acute responses may support coaches and athletes in optimizing strength training responses during drop-set sessions into their periodization.
Syndromic Craniosynostosis in a Child With Fontaine Progeroid Syndrome: A Rare Genetic Disorder and the Surgical Management

We present a case of cranial vault remodeling in a patient with Fontaine Progeroid Syndrome. At birth, the patient presented with midfacial retrusion, pansynostosis, and significant agenesis of the central vertex skull. Genetic testing revealed a de novo variant in the SLC25A24 gene, confirming the diagnosis of Fontaine Progeroid Syndrome. For craniosynostotis management of her pansynostosis and the large central vertex agenesis, surgical reconstruction was purposely delayed to allow ossification of the cranial vault. Subsequently, the cranial vault expansion was performed at the age of 4. Intraoperatively, significant dense adherence of bilateral temporal, parietal, and frontal bones to the underlying dural lakes was noted. This is the first case report known in the literature regarding suggested surgical management of the syndromic craniosynostosis with an enormous central skull agenesis.