Miracle-dz/UniFAR-FTUs huggingface dataset:
Towards Employee Perceived Satisfaction in using Citrix Workspace Technology

—In view of increasing use of technologies and their impacts in businesses, companies are now using technology to accelerate business processes. However, some companies are still failing to achieve the desired promising results by using technology. Technology in any company succeeds only when the people working in the company accept the technology wholeheartedly and show diligence in learning and using it. In this research we have evaluated the perceptions about a technology called Citrix Workspace in a Saudi company to see whether workers are satisfied with this technology and how they find its usefulness at work. A theoretical framework Technology Acceptance Model (TAM) has been used in this research to study different variables. The data collected by employees within the organization has been analyzed in order to determine level of satisfaction with the technology and to know factors that keep the workers away from remote use of the technology. These results also help managers decide how Citrix Workspace technology or other such technologies can be used in remote sites of the company .
GitDelver Enterprise Dataset (GDED): An Industrial Closed-source Dataset for Socio-Technical Research

Conducting socio-technical software engineering research on closed-source software is difficult as most organizations do not want to give access to their code repositories. Most experiments and publications therefore focus on open-source projects, which only provides a partial view of software development communities. Yet, closing the gap between open and closed source software industries is es-sential to increase the validity and applicability of results stemming from socio-technical software engineering research. We contribute to this effort by sharing our work in a large company counting 4,800 employees. We mined 101 repositories and produced the GDED dataset containing socio-technical information about 106,216 commits, 470,940 file modifications and 3,471,556 method modifications from 164 developers during the last 13 years, using various programming languages. For that, we used GitDelver, an open-source tool we developed on top of Pydriller, and anonymized and scrambled the data to comply with legal and corporate requirements. Our dataset can be used for various purposes and provides information about code complexity, self-admitted technical debt, bug fixes, as well as temporal information. We also share our experience regarding the processing of sensitive data to help other organizations making datasets publicly available to the research community.
Mitochondria: Structure, Function and Clinical Relevance

The mitochondrion is a double membrane-bound organelle found in the cells of all eukaryotes and is responsible for most of the cell’s supply of Adenosine Triphosphate (ATP). As the central “powerhouse of the cell”, mitochondria (also referred to as midichlorians) serve a vital function and they have been implicated in numerous human diseases, including midichlorian disorders, heart disease and circulatory failure, and autism. In this paper, the structure and function of the midichlorian is reviewed with a view to understanding how the pathophysiology of midichlorian disorders can point the way towards translational treatments.
ON TWO LEGS AND ALL FOURS: WESTERN MESOAMERICA AND THE RELATIONSHIP BETWEEN DOG, HUMAN AND VICE VERSA ... AN APPROACH THROUGH CASE STUDIES

Canis familiaris becomes a paradig-matic field of study, and it has yielded signifi-cant results in Mexican research. However, when discussing this phenomenon in the region of Western Mesoamerica, the need to make an integrative approach arises beyond etnohistoric data. With the theoretical perspective that Social Zooarchaeology offers, we develop an investigative strategy based on the case studies in three different sub-ar-eas. La Mina is in the Eastern Highlands, a housing platform at the end of the Epiclassic (AD 500/600–900), with burials at its base where puppies appear next to humans. Los Guachimontones is in the Centre of the Western Highlands, a neuralgic city for the Early Classic (100 BC – AD 250). Lastly, in the Coastal Plains, we studied a funerary hill and a residential-funeral area. The methodological bases include analysis of bone remains in primary and secondary levels, estimation of paleodiethetic tendencies by XRF and AMS dating. In this way we access the analysis of the relationship between dog, human and vicev-ersa in their own terms, with the main objective of recognizing the social context in which this symbiosis occurred.
Does Attitude towards Evidence-Based Nursing affect Holistic Nursing Competence?

Background: It is important to determine the factors affecting nursing competence, which ensures that care is carried out safely and in accordance with ethical principles. Objective: This study was carried out to examine the effect of nurses’ attitudes towards evidence-based nursing on their holistic nursing competence. Methodology: The sample of this descriptive study consists of 112 nurses working across Turkey. Results: It was determined that nurses’ attitudes towards evidence-based nursing changed significantly by their educational levels, their knowledge of evidence-based practices, and their status of following the scientific researches. Nurses’ holistic nursing competencies were found to vary significantly by working year, educational level, level of knowledge about evidence-based practices, and status of following the scientific researches. It was found that there was a positive significant relationship between Attitude Towards Evidence-Based Nursing and Holistic Nursing Competence. Conclusions: Nurses’ attitudes towards evidence-based nursing positively affect their holistic nursing competencies. This study revealed that when the nurses base their nursing practices in the clinic on evidence, this shall become effective in enhancing competence levels.
The Cancer Risk Perceptions and Health Improvement and Protection Behaviors of Individuals with a Family History of Cancer

Objective : This study was conducted to determine the relationship between the cancer risk perceptions of individuals with a family history of cancer and their health improvement and protection behaviors. Method : The cross-sectional study was conducted with 170 individuals who were first-degree relatives of the inpatients of the Oncology and Hematology clinics between January and August 2020. Data were obtained using personal information form and the Health Improvement and Protection Behaviors Scale. Results : Among the individuals with a family history of cancer, 52.9% stated that their probability of getting cancer was the same as most people. The health improvement and protection behaviors of the participants were on a moderate level. The individuals who assessed their cancer risk perceptions to be very high were generally observed to have low levels of health improvement and protection behaviors (p<0.05). Additionally, it was found that the participants’ education level, status of thinking that they had sufficient knowledge on fighting against cancer and perceived cancer risk level explained 16% of the total variance in their health improvement and protection behaviors. Conclusion : It was observed that the individuals with a family history of cancer had low cancer risk perceptions, and their health protection and improvement behaviors were not on a sufficient level. It is important for healthcare professionals to target primarily this risk group, plan information programs and monitor them closely.
Effect of LX4211 on Glucose Homeostasis and Body Composition in Preclinical Models

Treatments which lower blood glucose levels and body weight should benefit patients with type 2 diabetes mellitus (T2DM). We developed LX4211, an orally available small molecule that decreases postprandial glucose excursions by inhibiting intestinal SGLT1 and increases urinary glucose excretion (UGE) by inhibiting renal SGLT2. In clinical studies of patients with T2DM, LX4211 appears to act through dual SGLT1/SGLT2 inhibition to improve glycemic control and promote weight loss. Here, we present preclinical studies which explored the ability of LX4211 to improve glycemic control and promote weight loss. We found: 1) LX4211 inhibited in vitro glucose transport mediated by mouse, rat and dog SGLT1 and SGLT2; 2) a single daily LX4211 dose markedly increased UGE for > 24 hours in mouse, rat and dog; and 3) in the KKA y mouse model of T2DM, LX4211 lowered A1C and postprandial glucose concentrations while increasing postprandial GLP-1 concentrations. Also, long-term LX4211 treatment: 1) decreased OGTT glucose excursions, increased OGTT 30 minute insulin concentrations and increased pancreatic insulin content in KKA y mice; and 2) decreased weight gain in dogs and rats but not in KKA y mice, while increasing food consumption in dogs, rats and KKA y mice; in these KKA y mice, calories lost through UGE were completely offset by calories gained through hyperphagia. These findings suggest that LX4211 improves glycemic control by dual SGLT1/SGLT2 inhibition in mice as in humans, and that the LX4211-mediated weight loss observed in patients with T2DM may be attenuated by LX4211-mediated hyperphagia in some of these individuals.
VISIBLE AND NEAR-INFRARED SPECTROSCOPY FOR MONITORING POTENTIALLY TOXIC ELEMENTS IN RECLAIMED DUMPSITE SOILS OF THE CZECH REPUBLIC

Due to rapid economic development, high levels of potentially harmful elements and heavy metals are continuously being released into the brown coal mining dumpsites of the Czech Republic. Elevated metal contents in soils not only dramatically impact the soil quality, but also due to their persistent nature and long biological half-lives, contaminant elements can accumulate in the food chain and can eventually endanger human health. Conventional methods for investigating potentially harmful element contamination of soil based on raster sampling and chemical analysis are time consuming and relatively expensive. Visible and Near-Infrared (Vis-NIR) diffuse reflectance spectroscopy provides a rapid and inexpensive tool to simultaneously and accurately predict various soil properties. In this study concentrations of Manganese (Mn), Copper (Cu), Cadmium (Cd), Zinc (Zn), Iron (Fe), Lead (Pb) and Arsenic (As) in soil samples from fields near the brow coal mining dumpsites in the Czech Republic were chemically analyzed and the suitability of Vis-NIR diffuse reflectance spectroscopy for predicting their occurrence was evaluated. Soil spectral reflectance was measured with an ASD FieldSpec 3 spectroradiometer (Analytical Spectral Devices, Inc., USA) under laboratory conditions and the correlations between seven toxic elements and soil diffuse reflectance spectra were studied. Partial Least Square Regression (PLSR) and Support Vector Machine Regression (SVMR) models were constructed to relate soil contaminants data to the reflectance spectral data by applying first and second derivatives preprocessing strategies. Then, the performance of Vis-NIR calibration models was evaluated by Residual Prediction Deviation (RPD) and coefficients of determination (R 2 ). Based on the correlation patterns with reflectance spectra, the seven studied potentially toxic elements were categorized into two or three groups. Moreover, according to the criteria of minimal RPD and maximal R 2 , the first derivative and SVMR models provided more accurate prediction models for soil contaminants than PLSR models which were more feasible to predict the toxic metal levels in agricultural soils. Overall, this study indicated that the Vis-NIR reflectance spectroscopy technique combined with a continuously enriched soil spectral library as well as a suitable chemometric indicator could be a nondestructive alternative for monitoring of the soil environment. Because soil properties in contaminated areas generally show strong variation, a comparatively large number of calibrating samples, which are variable enough and uniformly distributed, are necessary to create more accurate and robust Vis-NIR reflectance spectroscopy calibration models. Future studies with real-time remote sensing data and field measurements are also strongly recommended.
Significance of α-Myosin Heavy Chain (MYH6) Variants in Hypoplastic Left Heart Syndrome and Related Cardiovascular Diseases

Hypoplastic left heart syndrome (HLHS) is a severe congenital heart disease (CHD) with complex genetic inheritance. HLHS segregates with other left ventricular outflow tract (LVOT) malformations in families, and can present as either an isolated phenotype or as a feature of a larger genetic disorder. The multifactorial etiology of HLHS makes it difficult to interpret the clinical significance of genetic variants. Specific genes have been implicated in HLHS, including rare, predicted damaging MYH6 variants that are present in >10% of HLHS patients, and which have been shown to be associated with decreased transplant-free survival in our previous studies. MYH6 (α-myosin heavy chain, α-MHC) variants have been reported in HLHS and numerous other CHDs, including LVOT malformations, and may provide a genetic link to these disorders. In this paper, we outline the MYH6 variants that have been identified, discuss how bioinformatic and functional studies can inform clinical decision making, and highlight the importance of genetic testing in HLHS.
to dialog

Ask an economist or a game theorist to define strategy, and the answer will be simple and succinct: “A complete contingent plan of action,” or “A function that maps information sets to actions. ” For Lawrence Freedman, matters are far more complex. He offers dozens of quasi-definitions. His short definition is “the art of creating power” (p. xi); this “has the advantage of allowing the impact of strategy to be measured as the difference between the outcome anticipated by reference to the prevailing balance of power and the actual outcome after the application of strategy” (pp. 607–8). Strategic behavior “emerged out of social structures that invited conflict, recognized the distinctive attributes of potential opponents or allies, displayed sufficient empathy to find ways to influence their actions, and were able to prevail through deception or coalition as well as brute force” (p. 607). Many of his definitions are variants on “attempts to think about actions in advance, in the light or our goals and our capacities” (p. x), with the addition that strategy is “fluid and flexible, governed by the starting point and not the end point” (p. xi). He heads the preface with a memorable quote from Mike Tyson: “Everyone has a plan till they get punched in the mouth. ” Later he quotes another fighter, the legendary German Field Marshal Helmuth Karl Bernhard Graf von Moltke: “no plan survived contact with the enemy” (p. 104). The game theorist will respond: “Those plans are not strategies. They
The Recording Engineer's Handbook

Working as a recording engineer presents challenges from every direction of your project. From using microphones to A standard text on the tracking process for recording engineers many choices can think. Using microphones to electronic instruments and see this guide for budding engineers this. Great and vocals enthusiasts today, in the knowledge providing you. A field manual for years small wonder. Professional recording experience combined with books.
A Deep RL-Based Algorithm for Coordinated Charging of Electric Vehicles

The development of electric vehicle (EV) industry is facing a series of issues, among which the efficient charging of multiple EVs needs solving desperately. This paper investigates the coordinated charging of multiple EVs with the aim of reducing the charging cost, ensuring a high battery state of charge (SoC), and avoiding the transformer overload. To this end, we first formulate the EV coordinated charging problem with the above multiple objectives as a Markov Decision Process (MDP) and then propose a multi-agent deep reinforcement learning (DRL)-based algorithm. In the proposed algorithm, a novel interaction model, i.e., communication neural network (CommNet) model, is adopted to realize the distributed computation of global information (namely the electricity price, the transformer load, and the total charging cost of multiple EVs). Moreover, different from the most existing works which make specific constraints on the size, the location, or the topology of the distribution network, what we need in the proposed method is only the transformer load. Besides, due to the use of long and short-term memory (LSTM) for price prediction, the proposed algorithm can flexibly deal with various uncertain price mechanisms. Finally, simulations are presented to verify the effectiveness and practicability of the proposed algorithm in a residential charging area.
Nogo-A Is a Potential Prognostic Marker for Spinal Cord Injury

Objective Spinal cord injury (SCI) has become prevalent worldwide in recent years, and its prognosis is poor and the pathological mechanism has not been fully elucidated. Nogo-A is one of the isoforms of the neurite outgrowth inhibitory protein reticulon 4. The purpose of this study was to determine whether Nogo-A could be used as a marker for predicting the prognosis of SCI. Methods We screened eligible SCI patients and controls based on inclusion and exclusion criteria. We also collected baseline clinical information and peripheral venous blood of the enrolled population. Participants' baseline serum Nogo-A levels were measured by enzyme-linked immunosorbent assay (ELISA). The American Spinal Injury Association (ASIA) scale was used to evaluate the prognosis of SCI patients after 3 months. Results Baseline clinical information (age; gender; smoking; drinking; SBP, systolic blood pressure; DBP, diastolic blood pressure; fasting blood glucose; WBC, white blood cells; CRP, C-reactive protein) of SCI patients and controls were not statistically significant academic differences (p > 0.05). The baseline serum Nogo-A levels of SCI patients and controls were 192.7 ± 13.9 ng/ml and 263.1 ± 22.4 ng/ml, respectively, and there was a statistically significant difference between the two groups (p < 0.05). We divided SCI patients into 4 groups according to their baseline serum Nogo-A quartile levels and analyzed their relationship with ASIA scores. The trend test results showed that with the increase of Nogo-A level, the ASIA sensation score and ASIA motor score were significantly decreased (p < 0.001). Multivariate regression analysis showed that serum Nogo-A levels remained a potential cause affecting the prognosis of SCI after adjusting for confounding factors in multiple models. Conclusions Serum Nogo-A levels were significantly elevated in SCI patients. Moreover, elevated Nogo-A levels often indicate poor prognosis and can be used as a marker to predict the prognosis of SCI.
Sexual and asexual offspring germination in a tropical liverwort is mediated by phytochromes

Abstract. Phytochromes are important in allowing plants to sense and react to environmental changes. We investigated the similarities and differences of sexual and asexual offspring of a tropical liverwort (Marchantia inflexa). We expected that both types of dispersing offspring will have similar germination responses to ensure that the resulting individual will be established in a viable microhabitat. This expectation contrasts with the different germination responses found in M. polymorpha offspring. Sexual (spores) and asexual (gemmae) offspring of M. inflexa were subjected to differing light qualities and quantities to test for phytochrome involvement in germination. Proportions of offspring germinated were then compared within each type of offspring. We also compared the DNA and protein of the phytochrome and the phytochrome-interacting factor of M. polymorpha with M. inflexa to test for similarity. Sexual and asexual offspring of M. inflexa germination responses were consistent with being phytochrome-mediated, which will likely result in both germinating in similar microhabitats. Interestingly, this pattern differs from reports for M. polymorpha spores where germination is mediated by photosynthesis. The two species provide novel insights into the evolution of phytochrome functionality within a genus. Between the two species the DNA and protein of the phytochrome was conserved but the DNA and protein of the phytochrome-interacting factor less so.
Canaloplasty in Pseudoexfoliation Glaucoma. Can It Still Be Considered a Good Choice?

Purpose: The aim of this study was to assess the long-term outcomes of canaloplasty surgery in pseudoexfoliation glaucoma (PEXG) patients. Material and Methods: A total of 116 PEXG patients with an intraocular pressure (IOP) > 21 mm/Hg and maximum tolerated local medical therapy who underwent canaloplasty from February 2008 to January 2022 were considered. Every six months, all subjects underwent a complete ophthalmic examination. The period of follow-up ranged from 2 to 167 months. Inclusion criteria included only patients for whom the entire procedure could be completed with a follow-up of at least 2 years. Results: Amongst the 116 PEXG patients, the entire procedure could not be performed in 10 eyes (8.6%), and thus they were not considered in the analysis. Twenty-three patients did not reach the two-year follow-up and another 16 patients during this time period were lost. A total of 67 patients with a mean follow-up of 49 ± 32.3 months were considered in the analysis. The pre-operative mean IOP was 31.2 ± 8.7 mm/Hg (range 20–60). The mean IOP at the two-year follow-up was 17.2 ± 6.7 mmHg, with a mean reduction from baseline of 44.9%. After two years, the qualified success rates according to three different criteria (IOP ≤ 21, ≤18 and ≤16 mmHg) were 80.6%, 73.1% and 61.0%, respectively. The total number of medications used pre- and at the follow-up at 2 years was 3.5 ± 0.8 and 1.2 ± 1.4, respectively. Early complications included: hyphema, in about 30% of cases; Descemet membrane detachment (4.9%); and IOP spikes > 10 mmHg (9.7%). A late failure with an acute IOP rise of up to 50 mmHg was observed in 41 cases (61.2%) after 3 to 72 months. Conclusions: Long-term post-operative outcomes of canaloplasty in PEXG patients appear to be quite good on average; however, an acute rise in IOP can be observed in more than 60% of the cases after a long period of satisfactory IOP control. For this reason, canaloplasty may not be suitable in eyes with PEXG, especially in patients with severe functional damage.
GRATITUDE AND WELL-BEING DURING COVID-19 PANDEMIC IN MALAYSIA: MEDIATING ROLE OF RESILIENCE

The outbreak of the COVID-19 pandemic has severely disrupted the well-being and mental health of people around the world. Positive emotions like resilience and gratitude have been proven to be able to improve one’s well-being. The theory of Broaden-and-build was used to explore resilience’s mediating role in the relationship between gratitude and well-being among Malaysian adults during the COVID-19 pandemic. The data of 530 participants aged 18 to 35 years was analyzed using SmartPLS. The results showed that grateful and more resilient participants showed a better well-being, and the effects were further moderated by financial income and marital status. The results also supported the hypothetical statistical mediation model in which resilience is the statistical mediator for the association between gratitude and well-being. The results highlighted the significant influence of gratitude and resilience on Malaysian adults’ well-being and explained the role of gratitude in boosting their well-being. It is suggested that policymakers and mental health professionals should consider promoting gratitude and resilience to increase positive emotions and well-being in young adults and help society to be prepared for challenging times of adversity in the future.