Miracle-dz/UniFAR-FTUs huggingface dataset:
Critical Review on Hadith Application in Google Play Store from 2017-2023

Beside Qur'an, the study of Hadith is the second main source of Islamic Teaching. Despite the age's more rapid growth and the rise of technology as a method of communication and knowledge communication technology (ICT) in this era of digitization has given a new dimension to the understanding of hadith. Numerous initiatives have been created to enhance, sustain, and preserve to learn Hadith in digital platform. The availability of Hadith applications nowadays significantly assists Muslims in better understanding and applying Science of Hadith in their daily lives. However, there are several Hadith application methods available to Muslims on a variety of current platforms. There are a lot of programmes in the Google Play Store, so it can be difficult to identify which ones have pros and cons. In order to analyse data and assess the usability of hadith applications accessible in the Google Play Store, this study used the Hands-On Measurement approach. Following data analysis and usability evaluation based on a variety of crucial mobile application needs, including as learnability, efficiency, memory, error management, and satisfaction, thirty hadith apps from the Google Play Store were selected for a shortlist. According to the study, Muslims can utilise the hadith applications that are available on the Google Play Store as a source of
Robust Walking Direction Estimation via Principal Component Pursuit in Pedestrian Dead Reckoning

In pedestrian dead reckoning (PDR) systems, accurate estimation of the walking direction is of paramount importance for achieving high localization accuracy. Despite numerous research endeavors in this area, a remaining challenge lies in cases where the direction indicated by the sensors does not align with the actual pedestrian's walking direction. In this paper, we address this misalignment problem by focusing on the PCA-based method. While this method exploits the advantages of PCA, it is also subject to its limitations, notably its susceptibility to outliers due to abnormal actions beyond normal walking, which are commonly encountered in PDR scenarios. To ensure robustness against outliers, we propose a novel PCA-based method for estimating the walking direction. Through experiments conducted on various actions, we evaluate the performance of the proposed method. The results demonstrate that our proposed method, which applies stable principal component pursuit for robust PCA, achieves an improved performance with an RMSE of 5.15° compared to classical PCA. Furthermore, the proposed method exhibits stable estimation and robustness across all presented actions and sequences.
Effect of Camphor Incorporation on the Material and Antibacterial Properties of Soy Protein Isolate Films

Seeking for green alternatives to synthetic plastics, soy protein based plastics are becoming quite a popular choice. Soy protein isolate (SPI) is a plant derived protein that holds fair film forming abilities. It demonstrates evenness of film surface, decent tensile strength and interacts easily with a wide range of additives. Additives are generally added to improve the material properties and antibacterial nature of the film. In this study, we have explored the effect of camphor incorporation on the material properties and overall performance of the film. SPI based films (having 7% SPI (w/v)) were prepared by solution casting method. The concentration of camphor was varied from 0.5 to 3% w/w of 7% SPI. The films prepared by camphor addition were characterized for their transmittance, Fourier Transform Infrared (FTIR) spectroscopy and mechanical properties. The FTIR spectra confirm the incorporation of camphor as a major change in the band intensity was seen compared to neat films. However, camphor addition made the films hydrophilic and a noticeable decrease in the tensile strength was seen. The water vapour transmission rate increased upon camphor addition as compared to neat SPI films. Nevertheless, camphor- SPI film was stable as very minimum leaching occurred during the study. Unlike the neat camphor solution (1-3% w/v), the camphor modified SPI films didn’t exhibit antibacterial activity against Listeria monocytogenes and Escherichia coli. Camphor was seen to significantly increase the antioxidant properties of SPI films.
Design and discovery of a highly potent ultralong-acting GLP-1 and glucagon co-agonist for attenuating renal fibrosis by modulating mitochondrial function

GLP-1 receptor (GLP-1R) and glucagon receptor (GCGR) are critical for the maintenance of glucose and energy homeostasis, but their roles in chronic kidney disease (CKD) are still unknown. Herein we found that the expression of GLP-1R and GCGR was lower in kidney from patients with CKD than in control individuals and was correlated with disease severity. RNA-seq analysis showed that adeno-associated viral vector serotype 9-GLP-1R or GCGR small hairpin RNA (AAV9-GLP-1R or GCGR shRNA) treatment in db/db mice exhibited more advanced diabetic nephropathy than wild-type mice. We also found that GLP-1R mainly expressed in glomeruli and GCGR expressed in both glomeruli and tubuli renales. Based on the importance of GLP-1R and GCGR in CKD, we design and report a new monomeric peptide, 1907-B, with agonism at the GLP-1R and GCGR that have more prolonged half-time than long-acting semaglutide in cynomolgus rats or monkeys (~2-3 fold) and exhibit better therapeutic contribution to CKD than best-in-class monoagonists, semaglutide or glucagon in db/db mice and unilateral ureter obstruction (UUO) mice. Various loss-of-function models, including selective pharmacological blockade and genetic knockdown, confirmed that the effects of 1907-B on improving glucose control and ameliorating the diabetic nephropathy in db/db mice were mediated through GLP-1 and glucagon signaling, whereas its action on inhibiting renal fibrosis in UUO mice was predominantly mediated through glucagon signaling. Mechanistically, 1907-B activated downstream cAMP-PKA pathway to promote mitochondrial biogenesis and bioenergetics, as well as to attenuate renal oxidative stress under chronic hyperglycemia via stimulating GLP-1R and GCGR simultaneously. Furthermore, 1907-B had crucial protection roles against inflammation via NFκB pathway and renal fibrosis via TGF-β-SMAD pathway. Thus 1907-B, via direct kidney (GCGR) and part-glomerulus (GLP-1R) effects, exerts multifactorial improvement in renal injuries and is a more effective and promising therapeutic option for the treatment of CKD.
EU-Net: Efficient Dense Skip-Connected Autoencoder for Medical Image Segmentation

This paper introduces EU-Net, an efficient and enhanced U-Net-like architecture designed for medical image segmentation. It comprises a lightweight encoder and decoder connected through dense skip-connections. To further improve the robustness of the EU-Net, chain EU-Net is proposed. Chain EU-Net is based on a streamlined architecture that uses multiple EU-Net to build light weight deep neural networks by dense skip-connection. Compared to traditional segmentation algorithms such as U-Net and its variants, our neural network structure possesses both lightweight and stability simultaneously. EU-Net and chain EU-Net are evaluated on three typical medical image segmentation tasks: GLAS (Gland segmentation) dataset, RITE (Retinal Images Vessel Tree Extraction) dataset and LiTS (Liver Tumor Segmentation Challenge) dataset. In addition, we used PUFH (Peking University First Hospital) dataset. Experimental results show that the proposed methods achieve state-of-the-art performance with very few parameters.
Evidence for a weak and overpressured décollement beneath sediment‐dominated accretionary prisms

We present structural data from several underthrust sequences in southwest Alaska that suggest that the deformation regime beneath accretionary prisms is characterized by a subvertical σ1 and regionally extensive layer-parallel shearing. These results contrast markedly with the results obtained from the more shallow parts of accretionary prisms and fold and thrust belts where σ1 plunges gently seaward or toward the deformation front. On the basis of Mohr circle diagrams, we propose that these different stress directions are consistent only with a model in which the two regimes are separated by a very weak decollement and calculate coefficient of friction values that range from 0.25 to 0.08. These values are significantly lower than coefficient of friction values calculated for the basal decollement in the Taiwan fold and thrust belt (e.g., ±0.2 (Barr and Dahlen, 1989a)) and they are also lower than laboratory friction measurements for most rocks (e.g., 0.6–0.8 (Byerlee, 1978)). Consequently, these low values suggest the presence of rocks with unusual material properties (e.g., montmorillonite (Logan and Rauenzahn, 1987)) or anomalous fluid pressures along the decollement. On the basis of the occurrence of shale diapirs, the distribution of early veins, and the absence of montmorillonite in the underthrust sequences, we propose that there was an anomalously high fluid pressure along the decollement fault instead of there being such a low coefficient of friction. These results emphasize the importance of dewatering and fluid flow in controlling the position of the decollement, which in turn determines how the accretionary prism grows. In essence, it is the development of a weak, overpressured decollement within a thick sediment pile that allows plate convergence to be partitioned into offscraping and underthrusting regimes.
Case report: A new de novo mutation of the Troponin T2 gene in a Chinese patient with dilated cardiomyopathy

Dilated cardiomyopathy (DCM) is a cardiovascular disease characterized by persistent ventricular dilatation and systolic dysfunction. DCM has a variety of causes, including myocarditis; exposure to narcotics, alcohol, or other toxins; and metabolic or endocrine disorders. Genetic factors play a dominant role in 30%–40% of DCM cases. Here, we report a case of DCM with very severe heart failure. Because of the severity of heart failure, the patient underwent heart transplantation. We speculated that the patient's DCM might be due to a mutation; hence, we performed whole-exome sequencing of the patient and their parents, which showed a de novo heterozygous mutation (NM_001001431.2c.769G>A:p.E257K) in TNNT2, which was considered pathogenic according to the ACMG pathogenicity assessment. This finding expands the genetic map of DCM and TNNT2 and will be important for future studies on the genetic and disease relationships between DCM and TNNT2.
Archaeozoological Records for the Highlands of New Guinea: A Review of Current Evidence

Abstract Archaeozoological records for seven occupation sites in the highlands of New Guinea are presented and reviewed. The sites were originally excavated between 1959 and 1981. More recent excavations have not documented comparable archaeozoological records. This paper aims to summarise unpublished research, together with some previously published results, for a broader audience, and elicit general trends within the data. Of significance are methodological insights, observations on Pleistocene and Holocene extinctions and the introduction of exotic fauna, and implications for understanding land-use and socio-economic histories during the late Holocene.
xCovNet: A wide deep learning model for CXR-based COVID-19 detection

The high death toll and economic impact of the COVID-19 pandemic emphasize the need for effective population screening technologies. The high cost, limited availability, and slow nature of CT scans and PCR-based tests renders them impractical for frequent use among the general public. As chest X-ray (CXR) imaging is fast and economical, a high accuracy CXR-based test would be well-suited for such screenings. Deep learning algorithms are widely used to aid medical image diagnoses. We use a collection of state-of-the-art pre-trained deep neural network models with additional layers to detect the COVID-19 cases from a sample of healthy, COVID-19, and pneumonia patients. We observed models trained with concatenated features of multiple pre-trained deep learning architectures outperform the individual and ensemble models. Our final model obtained a recall of greater than 98% and a precision of greater than 95% on two separate datasets. The wide architecture of xCovNet may contribute to its robust behavior, providing a systematic approach to construct a reliable deep learning model for emerging datasets.
Exploring Electrical Impedance Tomography for Early Depth Detection of Pressure Ulcers

Pressure ulcers are a particularly high incidence of chronic trauma. When a superficial wound is visible, the underlying wound is often serious, so early detection of pressure ulcers is critical. Currently, there is still no technique or real-time monitoring system that can visualize progressive tissue damage of pressure ulcers. Electrical impedance tomography (EIT) is a functional imaging technique that can aid in the diagnose of tissue health by visualizing the distribution of bioelectrical impedance parameters. Based on the differences between the electrical properties of pressure ulcers and normal tissue, a noninvasive pressure ulcer depth detection method based on EIT is proposed. Given surface voltage data measured on an open rectangular electrode array, the conductivity distribution under the skin surface was reconstructed to obtain pressure ulcer depth information which is expected to visualize progressive tissue damage. Based on EIT combined with flexible sensor arrays, finite-element simulation models and tissue-mimicking agar phantom models were established to verify the effectiveness of the EIT-based depth detection method of pressure ulcers. The effects of time-difference imaging and frequency-difference imaging on the depth detection of pressure ulcer were compared. Both simulation and physical phantom experiments demonstrated the feasibility of EIT for detection of early pressure ulcer depth.
Letting It Be on a Continental Scale: Some Thoughts on Rewilding

LIKE A DULL TWO-BIT AXE, indolence cuts roughly both ways. As Americans and other modern peoples have become more and more dependent on machines—and thus lazier—some formerly cultivated areas of the overdeveloped continents have been abandoned. People have moved away from lands considered marginal for agriculture, forestry, and other extractive uses toward more fertile lands, with increasingly intensified production through modern technologies. This has harmed wild nature by increasing energy consumption and the concomitant extraction of fossil fuels, but it has also permitted large areas of the planet to grow back into native vegetation. An outstanding example is the eastern United States, where European settlers cleared most of the original forest to make way for agriculture and which is now again more than half-forested, though not yet with trees of presettlement stature and grandeur.
La calidad del servicio en los clubes de fútbol base de la región de Murcia. Una aplicación del análisis de importancia-satisfacción Services quality on grassroots football clubs in the region of Murcia. An application of the importance-performance analysis

Grassroots football clubs, key in the promotion of sport in school term, like any sport organization, must increase user satisfaction by o�耀ering high quality services. �怀is research proposes a quality assess - ment in order to design an improvement plan which shows evidence of overinvestment resource areas, areas of insuf�耀cient resources, and to make a proposal of improvement actions. With this aim, a questionnaire based on the SERVQUAL scale was administered to a sample of 1076 users of grassroots football clubs in the Region of Murcia, including 413 players, 366 parents, 207 coaches and 90 referees. �怀e results indicated that the strengths of grassroots football clubs in the Region of Murcia are mainly in aspects of responsiveness and assurance. �怀e weak points, however, are SFMBUFUPUBOHJCMFT��'VSUIFSNPSFJUXBTEFUFDUFEUIBUDPVMECFBOFYDFTTJWF�
Anthropometric indexes for predicting high blood pressure in Turkish adults

Purpose: It is controversial which anthropometric indexes are the best in predicting the risk of hypertension and how anthropometric measurements are related to blood pressure (BP). This study aimed to evaluate the relationship between BP and anthropometric indexes and to determine the best predictors for hypertension risk. Methods: This cross-sectional study was conducted with 415 consecutive participants (161 men, mean age: 33.4 years) aged 18–88 years in Istanbul, Turkey. Weight, height, waist circumference (WC), and neck circumference (NC) and BP were measured by well-trained personnel. Waist-to-height ratio (WHtR) and body mass index (BMI) were calculated. Pearson correlation, linear regression, and multivariate analyses were used to assess the relationship between anthropometric measurements and SBP, DBP, using the Statistical Package for the Social Sciences version 23.0. Results: The systolic BP (SBP) and diastolic BP (DBP) were related to weight, WC, NC, BMI, and WHtR (P < 0.05). Linear regression analyses showed BMI and WC as independent risk factors for SBP with an increase by 1.11 mmHg in men (P = 0.036) and 1.59 mmHg in women (P = 0.001) in SBP when BMI increased 1 unit, while SBP increases by 0.2 mmHg when WC increases by 1 unit regardless of gender (P = 0.013). Conclusion: Our results showed that BMI and WC are related to BP and important predictors of hypertension risk. Therefore, the uses of BMI and WC are recommended as screening tools for the prediction of hypertension risk among Turkish adults.
Prediction Model of Postoperative Pain Exacerbation Using a Wearable Electrocardiogram Sensor

Few studies have evaluated postoperative pain in real patients using biosignal sensors. We aimed to develop a prediction model for postoperative pain exacerbation using a wearable electrocardiogram (ECG) sensor and an intravenous patient-controlled analgesia (IV-PCA) device. We collected ECG and IV-PCA data from eight patients who underwent laparoscopic gastrointestinal surgery. Finally, an AutoEncoder model predicted postoperative pain exacerbation with a true positive rate of 60% and a false positive rate of 1.94 times/h.
COVID-19 ORF3a Viroporin-Influenced Common and Unique Cellular Signaling Cascades in Lung, Heart, and the Brain Choroid Plexus Organoids with Additional Enriched MicroRNA Network Analyses for Lung and the Brain Tissues

Tissue-specific implications of SARS-CoV-2-encoded accessory proteins are not fully understood. SARS-CoV-2 infection can severely affect three major organs—the heart, lungs, and brain. We analyzed SARS-CoV-2 ORF3a interacting host proteins in these three major organs. Furthermore, we identified common and unique interacting host proteins and their targeting miRNAs (lung and brain) and delineated associated biological processes by reanalyzing RNA-seq data from the brain (COVID-19-infected/uninfected choroid plexus organoid study), lung tissue from COVID-19 patients/healthy subjects, and cardiomyocyte cells-based transcriptomics analyses. Our in silico studies showed ORF3a interacting proteins could vary depending upon tissues. The number of unique ORF3a interacting proteins in the brain, lungs, and heart were 10, 7, and 1, respectively. Though common pathways influenced by SARS-CoV-2 infection were more, unique 21 brain and 7 heart pathways were found. One unique pathway for the heart was negative regulation of calcium ion transport. Reported observations of COVID-19 patients with a history of hypertension taking calcium channel blockers (CCBs) or dihydropyridine CCBs had an elevated rate of intubation or increased rate of intubation/death, respectively. Also, the likelihood of hospitalization of chronic CCB users with COVID-19 was greater in comparison to long-term angiotensin-converting enzyme inhibitors/angiotensin receptor blockers users. Further studies are necessary to confirm this. miRNA analysis of ORF3a interacting proteins in the brain and lungs revealed 3 of 37 brain miRNAs and 1 of 25 lung miRNAs with high degree and betweenness indicating their significance as hubs in the interaction network. Our study could help in identifying potential tissue-specific COVID-19 drug/drug repurposing targets.
Carcass composition and physicochemical and sensory attributes of breast and leg meat from native Mexican guajolote (Meleagris g. gallopavo) as influenced by sex

Abstract The aim of the study was to compare carcass composition and physicochemical and sensory attributes of breast and leg meat from native Mexican guajolote (Meleagris g. gallopavo) as influenced by sex. For this, slaughter weight and carcass characteristics of male ( n=8 ) and female ( n=8 ) guajolotes raised traditionally under extensive systems with similar housing and feeding conditions were recorded. Also, physical characteristics, proximate composition, the fatty acid profile, and sensory attributes were determined in breast and leg meat using standard procedures. The results showed that males had higher ( P<0.001 ) slaughter weight, hot and cold carcass weights, and dressing percentage, as well as carcass part weights, while females had higher ( P<0.001 ) abdominal fat weights than males. The lightness ( L* ), yellowness ( b* ), and drip loss values of breast meat, as well as redness ( a* ) and water-holding capacity values of leg meat, were significantly ( P<0.05 ) influenced by sex. Male breast meat had higher ( P<0.05 ) moisture content, crude protein, erucic acid (C22:1n9), ∑ MUFAs (total monounsaturated fatty acids), ∑ UFAs (unsaturated fatty acids), ∑ DFAs (desirable fatty acids), ∑ UFA / ∑ SFA (total saturated fatty acid) ratio, ∑ PUFA (total polyunsaturated fatty acid) / ∑ SFA ratio, and chewiness scores than females. Likewise, leg meat from males showed higher ( P<0.05 ) ash content, myristic acid (C14:0), palmitic acid (C16:0), stearic acid (C18:0), oleic acid (C18:1n9c), palmitoleic acid (C16:1n7), ∑ SFAs, ∑ OFAs (odd fatty acids), thrombogenic index, and atherogenic index, whereas females had high fat content. In conclusion, it would be suggested that, from a nutritional point of view, the meat from male guajolotes was preferable to the meat from females.
An Invitro study to compare the antibacterial effect of different potencies of the Homoeopathic medicine Kreosotum and Metrogyl against Staphylococcus aureus

An experimental in vitro study was conducted at the Research Facilitation Centre of Sarada Krishna Homoepathic Medical College and Hospital to compare and analyse the antibacterial effect of different potencies of Kreosotum and Metrogyl against the gram-positive bacteria, Staphylococcus aureus. Notably, Kreosotum 200C, a particular Homoeopathic medicine, displayed the most potent antimicrobial activity, generating a substantial 7mm inhibition zone. This remarkable efficacy against Gram-Positive bacteria positions it as a viable treatment option for various ailments, including but not limited to Bacteraemia, Infective Endocarditis, Suppurative Affections (CSOM), Surgical Infections, Septic Shock, Septic Arthritis, and Nosocomial Infections.Future investigations should also focus on evaluating the in-vivo activity against Gram-positive bacteria to provide a comprehensive understanding of the therapeutic potential of Homoeopathic treatments in clinical settings.