Miracle-dz/UniFAR-FTUs huggingface dataset:
Analysis Pipeline : from raw Metagenomic Sequence Data to Metabolic Network Analysis

2 Analysis Pipeline: from raw Metagenomic Sequence Data to Metabolic Network Analysis 2 2.1 Prepare metagenomic sequence data . 3 2.2 Annotation of Metagenomic Sequence Reads . 3 2.3 Estimating the abundance of enzymatic genes . 5 2.4 Building reference metabolic dataset . 7 2.5 Constructing State Specific Network . 8 2.6 Topological network analysis . 9 2.7 Differential network analysis . 10 2.8 Network Visualization . 10
Correction

PSYCHOLOGICAL AND COGNITIVE SCIENCES PNAS is publishing an Editorial Expression of Concern regarding the following article: “Experimental evidence of massivescale emotional contagion through social networks,” by Adam D. I. Kramer, Jamie E. Guillory, and Jeffrey T. Hancock, which appeared in issue 24, June 17, 2014, of Proc Natl Acad Sci USA (111:8788–8790; first published June 2, 2014; 10.1073/ pnas.1320040111). This paper represents an important and emerging area of social science research that needs to be approached with sensitivity and with vigilance regarding personal privacy issues. Questions have been raised about the principles of informed consent and opportunity to opt out in connection with the research in this paper. The authors noted in their paper, “[The work] was consistent with Facebook’s Data Use Policy, to which all users agree prior to creating an account on Facebook, constituting informed consent for this research. ” When the authors prepared their paper for publication in PNAS, they stated that: “Because this experiment was conducted by Facebook, Inc. for internal purposes, the Cornell University IRB [Institutional Review Board] determined that the project did not fall under Cornell’s Human Research Protection Program. ” This statement has since been confirmed by Cornell University. Obtaining informed consent and allowing participants to opt out are best practices in most instances under the US Department of Health and Human Services Policy for the Protection of Human Research Subjects (the “Common Rule”). Adherence to the Common Rule is PNAS policy, but as a private company Facebook was under no obligation to conform to the provisions of the Common Rule when it collected the data used by the authors, and the Common Rule does not preclude their use of the data. Based on the information provided by the authors, PNAS editors deemed it appropriate to publish the paper. It is nevertheless a matter of concern that the collection of the data by Facebook may have involved practices that were not fully consistent with the principles of obtaining informed consent and allowing participants to opt out.
Gender, Age, Year of Course and Faculty: Factors Influencing the Risk of Eating Disorders

Background: The passage through university, as a complex experience, can heighten personal susceptibility to eating disorders. The objective of this research is to determine how gender, age, year of course, and center or faculty can influence the risk of an eating disorder among university students. Method: A transversal and descriptive study with a probabilistic sample of 516 Spanish students from 26 university degrees is performed, by administering the Inventory Eating Disorder-Reference criterion (EDI-3-RF) to the students. Results: It was found that the female students enrolled in second-year grades presented a greater obsession with thinness and body dissatisfaction, that the male students did more physical exercise to control their weight, and that those under 20 years and the students from both the Health and Law Faculties presented greater bulimic behavior. Conclusions: It is necessary to implement preventive measures adapted to the university students.
Journey from the Past to the Future in Raising the Ideal Physical Education Teacher: A Metaphor Study

The aim of this research is to examine the ideal physical education profile from the perspective of physical education teacher educators, that is, academicians working in the physical education and sports teaching department of the faculties of sports sciences. Within the scope of this purpose, the views of the academicians about the pre-graduate education, the undergraduate education period and their own teaching were compared with their views on the ideal physical education teacher. In order to express the comparisons more clearly, metaphor was used. The academicians were asked to match the physical education teachers who influenced them the most from their past to the future, their own teaching and their views on the ideal physical education teacher, with the nature metaphor presented to them by the researchers. In the study, which was based on the qualitative research method, the “interview” approach and the “interview form method” were used as the data collection method. According to the stratified sampling method, the participants of the study; taking into account the academic titles of the participants; 3 professors, 3 associate professors, 3 assistant professor and 3 lecturers A total of 12 physical education teacher educators (academics) were determined. As a result of the research, it was observed that while the participants defined their pre-graduate teachers closer to the ideal teacher in terms of their physical characteristics, they defined their undergraduate physical education teachers and themselves as closer to the ideal physical education teacher in the main themes of personality traits, teacher leadership styles and teaching methods.
Applications of the holographic principle in string theory

The holographic principle has become an extraordinary tool in theoretical physics, most notably in the form of the Anti-deSitter Conformal Field Theory (AdS/CFT ) correspondence, in which classical gravitational degrees of freedom in N -dimensions are related quantum field theory degrees of freedom in N 1 dimensions in the limit of a large number of fields. Here we present an account of the AdS/CFT correspondence, also known as the gauge/gravity duality, from its origins in the large N ’tHooft expansion, up to Maldacena’s proposal that type IIB string theory in the presence of D-branes at low energy is dual to an N = 4, d = 4, U(N) super Yang-Mills on AdS5 ⇥ S 5 . We begin with an extensive review of (super)string theory including D-branes. We then present the general formulation of the AdS/CFT in the supergravity background of AdS5 ⇥ S 5 , along with several examples of how it is used in terms of the identification of bulk fields with operators on the boundary of a CFT. We move on to discuss two applications of the gauge/gravity duality. The first is the application of the holographic gauge/gravity correspondence to the QCD k-string. The second applies the AdS/CFT formalism to a Kerr black hole solution embedded in 10-dimensional heterotic sting theory. These two applications of the holographic gauge/gravity duality comprise the original work presented here. We follow with summaries and discussions of the background material, the original work, and future investigations. vi TABLE OF CONTENTS LIST OF TABLES . xi LIST OF FIGURES . xii CHAPTER
Effect of soil and plant amendments on trace element uptake and distribution in crop plants

22 3.
Extending AI Planning to Solve more Realistic Problems

Applying AI planning to solve real-world problems is still difficult despite many attempts done in this area. Classical planning systems are able to handle a limited number of symbolic data elements, without taking into account the numerical aspect of many realworld problems. Some recent planners have moved to solve more realistic problems involving resource consumptions and time management (Bresina et al., 2002; Bacchus & Ady, 2001; Edelkamp, 2002), but the most of these planners deal with the numerical side of the planning problem as an assisting feature to a main symbolic problem, without being able to tightly mix the two sides of the problem to be solved as one homogeneous problem. However, there are still many real-world problems that involve dominant even absolute numerical processing (Zalaket & Camilleri, 2004b; Hoffmann et al., 2007) and for which planning problem representation and data type handling are to be extended. In order to cover this latter type of problems, we propose many extensions that allow the application of the planning process evenly over symbolic and numerical data that can constitute any realistic planning problem. Despite the multiple extensions that have been made to the Planning Domain Definition Language (PDDL) (Ghallab et al., 1998; Fox & Long, 2002; Gerevini & Long, 2005), this language is still insufficient for representing real-world problems that need complex action representation and complex state transformation expression. This lack motivates the organizers of the sixth international planning competition (IPC-6) to request a new extension to PDDL (the PDDL3.1 version). Inspiring from the continuous extensions to PDDL, we propose our first extension that concerns the data representation, in which we introduce the concept of using non-invertible functions to update the numerical and nonnumerical data throughout a planning process. This type of functions allows the integration and the handling in an easy way of uncertainty as well as of temporal and numerical knowledge into planning. As non-invertible functions can be only applied in forward traversal in a search space, hence we focus on the adaptation of forward planning systems to support the application of this kind of functions. We show that our technique can be used by any forward planner with a minor expansion, and we detail the extension of the Graphplan (Blum & Furst, 1995) structure and algorithm to support the execution of functions. The advantage of the
Use of video communication technology in the light of everyday and/or tele rehabilitation

Results: The scoping review shows that older patients (? 67 years), are mainly satisfied with reablement where VCT has been applied. From an employer's perspective, one should take into account that not everybody among the care personnel will be positive towards this type of service, although many studies also show relatively high satisfaction in the aforementioned group. It is essential that necessary support and training is provided to patients and care personnel, before municipalities establish such services.
Discovering and Mapping Colloquial Terminologies Describing Underutilized and Neglected Food Crops—A Comprehensive Review

Global levels of biodiversity and dietary diversity are decreasing, leading to food and nutrition insecurity. This is partially due to the homogenization of the global food supply with commodity crops. The reintroduction or introduction of neglected and underutilized species, minor, forgotten, and indigenous crops and landrace varieties to the wider food systems and further diversification have been outlined as the future strategies for tackling the above by the United Nations and the Food and Agriculture Organization in their policy frameworks. Most of the above species/crops are marginalized and only used across local food systems and in research. With over 15,000 different seed banks and repositories worldwide, information transparency and communication are crucial for database searching and their effective utilization. Much confusion persists around the true nature of those plants, and this prohibits the efficient utilization of their economic potential. A linguistic corpus search and a systematic literature review were conducted using the six most popular collocates to the above terms, which were as follows: ancient, heirloom, heritage, traditional, orphan, and the more distinct term ‘landrace’. The results were interpreted using the Critical Discourse Analysis method. The definitions’ findings show that heirloom, heritage, and ancient are mainly used in the United Kingdom and USA, where they are used to describe ‘naturalized’ and ‘indigenized’ or ‘indigenous’ food crops with a strong affiliation to ‘family’ and the ‘act of passing seeds down from generation to generation’. Orphan crops, on the other hand, are often described as being ‘overlooked’ by growers and ‘underfunded’ by researchers. Landrace is most strongly affiliated with ‘locality’, ‘biocultural diversity’, and ‘indigenous’, and with genomics literature, where the characteristics are often discussed in the context of genetics and population biology. Contextualizing, most of the terms were found to be ‘arbitrary’ and ‘undefinable’ due to their continuing evolution in the socially accepted form of language, perhaps apart from landrace. The review has retrieved 58 definitions for the mentioned 6 terms, together with the primary key terms creating a tool to facilitate a better inter-sector communication and aid in policy.
Determinants of RNA metabolism in the Schizosaccharomyces pombe genome - Appendix

3 Estimation of RNA metabolism rates from 4tU-Seq data 3 3.1 Overview . 3 3.2 Junction Model . 3 3.3 Exon model . 3 3.4 Uracil Bias . 4 3.5 Cross-contamination . 4 3.6 Expected number of reads given RNA species concentrations . 4 3.6. 1 Expected number of reads . 4 3.6. 2 Controlling for overall amount of labeled RNA and sequencing depth . 4 3.6. 3 Controlling for TU length . 4 3.7 Parameter estimation . 5 3.7. 1 Estimation of the dispersion parameter . 5 3.7. 2 Overall estimation procedure . 6 3.8 Rescaling of synthesis rate . 6 3.9 Comparison of junction and exon model . 6 3.10 Note on incorporation lag time . 7
Membrane partitioning during cell division.

INTRODUCTION . 323 MORPHOLOGICAL CHANGES . 324 Nuclear Envelope and Rough Endoplasmic Reticulum . 326 Golgi Apparatus . 327 Other Organelles . 329 MEMBRANE TRAFFIC . 329 Endocytosis . 329 Exocytosis . 331 Membrane Functions . 333 MECHANISM . 333 Fragmentation of the Nuclear Envelope and Golgi Apparatus . 334 Fragmentation in Interphase Cells . 336 Vesiculation of the Golgi Apparatus and Nuclear Envelope . 336 Reassembly of the Nuclear Envelope and Golgi Apparatus . 338 Role of Microtubules in Membrane Partitioning . 339 PARTITIONING ACCURACY . 339 Strategies . 339 Positioning of the Cleavage Furrow . 342 Budding Yeast . 342 Physiological Need for Partitioning . 343 SUMMARY AND FUTURE PROSPECTS . 343
Systems Neuroscience Review Article

In general, functional brain maturation is much more diffi cult to study than structural maturation because differences in observed brain activation can arise from differences in cognitive effort, experience , and strategy (Casey et al., 2005). This presents a signifi cant challenge for understanding the development of functional brain networks. The existing literature suggests that brain activation during a particular cognitive task tends to progress from more diffuse to more focal with age. Durston et al. (2006) were the fi rst to describe this notion of diffuse-to-focal changes in activation patterns in a longitudinal study of cognitive control. They demonstrated that over time, participants revealed an increase of magnitude of activation in key frontal areas with concomitant attenuation of activation in more widespread, nonspecifi c brain regions. They interpreted this to refl ect development of more effi cient processing. There is also evidence to suggest that with development, there are decreased demands on prefrontal cortex, with increased reliance on posterior brain regions (Rivera et al., 2005). However, there is often a complex relationship between changes in brain activation related to performance differences versus those related to brain maturation, and it is often diffi cult to match children on performance (Tamm et al., 2002). Even in cases where children, adolescents and adults are matched on accuracy,
Option contracts

Many languages support behavioral software contracts so that programmers can describe a component's obligations and promises via logical assertions in its interface. The contract system monitors program execution, checks whether the assertions hold, and, if not, blames the guilty component. Pinning down the violator gets the debugging process started in the right direction. Quality contracts impose a serious run-time cost, however, and programmers therefore compromise in many ways. Some turn off contracts for deployment, but then contracts and code quickly get out of sync during maintenance. Others test contracts randomly or probabilistically. In all cases, programmers have to cope with lack of blame information when the program eventually fails. In response, we propose option contracts as an addition to the contract tool box. Our key insight is that in ordinary contract systems, server components impose their contract on client components, giving them no choice whether to trust the server's promises or check them. With option contracts, server components may choose to tag a contract as an option and clients may choose to exercise the option or accept it, in which case they also shoulder some responsibility. We show that option contracts permit programmers to specify flexible checking policies, that their cost is reasonable, and that they satisfy a complete monitoring theorem.
Multipath Execution on Chip Multiprocessors Enabled by Redundant Threads

The performance penalty of mispredicted branches can be reduced by fetching/exe both paths of unconfident branches. Executing both paths of a branch involves forking a thread context for the non-predicted path. A key requirement is the ability to quickly copy reg and memory state, so that new threads are initiated quickly. Most multipath architectures ar on top of simultaneous multithreading (SMT), because a shared register file and cache e new threads to inherit state without any actual data movement. Multipath execution on chip m processors (CMP) is largely unexplored because per-thread register files and level-1 cach physically separated, making it difficult to quickly copy state. Redundant execution is proposed as an enabling mechanism for dual-path executio CMP with two processing elements (PEs). By always executing two programs, redundant s maintained continuously in preparation for forking. The threads redundantly and independ identify unconfident branches and explore alternative paths. When an unconfident b resolves, one of the threads falls behind. This is remedied by passing control flow and dat outcomes from the leading thread to the lagging thread. These are consumed as ideal branc predictions, enabling the lagging thread to catch up, ideally before the next unconfident br By being pro-active instead of reactive, redundant execution does not exhibit as much overh on-demand state copying. A completely distributed, CMP-based solution will generally underperform SMT-based s tions, yet performance improvements as high as 12% are measured. Latency for commun predictions between PEs affects performance significantly, but realistic latencies are tolera Multipath Execution on Chip Multiprocessors Enabled by Redundant Threads October 23, 2001 1 icted redicexeth is cause xts. ultiple he preed for nherit e does locatingleaps). sors g elearated preter file ainly ires a te is so d. dantly ontinare ep and execuconfin path llowed directs The via a branch leadation, . One proreads,
Patient experiences with the Forsus Fatigue Resistant Device.

OBJECTIVE To investigate patients' experiences with the Forsus Fatigue Resistant Device (FFRD). METHODS This was a survey focused on patient's comprehensive experience with FFRD, both initially and after several months of wear, including the patient's overall impression of the appliance. The survey was administered to 70 patients wearing FFRD in both university and private practice settings. RESULTS A high percentage (81.5%) reported a neutral to favorable experience with FFRD; 89.8% reported growing accustomed to the appliance within 4 weeks. The majority of those who had previously worn rubber bands found FFRD to be "easier. " Cheek irritation was the most serious side effect (about 50%). Cheek irritation and other negative effects generally decreased over time. CONCLUSIONS The FFRD is relatively well accepted by patients. Most patients experience some discomfort and functional limitations; however, the effect generally diminishes with time, and patients adapt to the appliance. Practitioners should be especially vigilant about problems with cheek irritation.
Abelian varieties over local and global fields

2 Abelian varieties over non-closed fields 14 2.1 Galois cohomology . 14 2.2 Local fields . 17 2.3 Duality for abelian varieties over local fields . 20 2.4 Global fields . 23 2.5 Brauer–Manin obstruction . 30
Management of sex workers and other high-risk groups.

Occupational Medicine 2007;57:322–328 doi:10.1093/occmed/kqm045
A Categorification of the Jones Polynomial

2 Preliminaries 5 2.1 The ring R . 5 2.2 The algebra A . 6 2.3 Algebra A and (1+1)-dimensional cobordisms . 7 2.4 Kauffman bracket . 8
ESC position paper Anticoagulants in heart disease : current status and perspectives ‡

List of abbreviations . 2 Preamble: purposes and scope of the task force . 2 Blood coagulation . 3 Haemostasis . 3 Arterial thrombosis . 3 Tissue factor . 3 Tissue factor pathway inhibitor . 3 Cellular control of coagulation . 3 Cross-talk between coagulation and inflammation . 4 Epidemiology of anticoagulant therapy in heart disease . 5 Coronary heart disease . 5 Non-valvular atrial fibrillation . 5 Prosthetic heart valves . 6 Heart failure . 6 Parenteral anticoagulants: general pharmacology . 6 Heparin derivatives . 6 Unfractionated heparin . 6 Mechanism of action . 6 Pharmacokinetics . 7 Dosing and monitoring . 7 Side effects . 8 Low molecular weight heparins . 8 Mechanism of action . 8 Pharmacokinetics . 8 Dosing and monitoring . 9 Side effects . 9 Pentasaccharides: fondaparinux and idraparinux . 9 Mechanism of action . 9 Dosing . 9 Monitoring . 9 Side effects . 9 Parenteral direct thrombin inhibitors . 10 Compared pharmacological properties of unfractionated heparin, low-molecular weight heparins, pentasaccharides, and direct thrombin inhibitors . 10 Vitamin K antagonists: general pharmacology . 11 Mechanism of action . 11 Vitamin K anticoagulant therapy: interference with foods and drugs . 11 Laboratory control . 11 Dosing . 12 Point-of-care testing and prothrombin time monitors . 13 Self-management of oral anticoagulation . 13 Oral direct thrombin inhibitors: general pharmacology . 14 Parenteral anticoagulants: clinical indications . 14 Unfractionated heparin . 14 Low molecular weight heparins . 14 Non-ST-elevation acute coronary syndromes . 14 ST-elevation acute myocardial infarction treated with fibrinolytics . 15 Elective percutaneous coronary interventions 15 Percutaneous coronary interventions in the setting of acute coronary syndromes . 16 Pentasaccharides . 16 Fondaparinux . 16 Idraparinux . 17 Intravenous direct thrombin inhibitors . 17 Vitamin K antagonists . 19 Coronary heart disease . 19 Primary prevention . 19 Acute coronary syndromes . 19 Coronary bypass graft surgery . 19 Percutaneous coronary interventions . 19 Atrial fibrillation . 19 Artificial heart valves . 19 Heart failure . 20 Oral direct thrombin inhibitors: clinical developments . 20 Oral Factor Xa inhibitors: clinical developments . 20 Bleeding risk and bleeding management during anticoagulant therapy . 21 General risk factors for bleeding . 21 Unfractionated heparin and low-molecular weight heparins . 21 Pentasaccharides . 21 Direct thrombin inhibitors . 21 Vitamin K antagonists . 22
Marketing y Publicidad: Integración de la publicidad BTL y ATL en una campaña publicitaria

x INTRODUCCIÓN . 1 CAPÍTULO I . 3 EL PROBLEMA . 3 1.1. Situación problemática. 3 1.2. Problema. 5 1.3. Justificación. 5 1.4. Objetivos. 7 1.5. Estado del arte. 7 CAPÍTULO II . 14 EL MIX DE LA COMUNICACIÓN DE MARKETING Y LA PUBLICIDAD INTEGRADA . 14 2.1. El mix de la comunicación de marketing. 14