Miracle-dz/UniFAR-FTUs huggingface dataset:
VIA ELECTRONIC SUBMISSION

This paper presents a one-year study of Internet packet traﬃc from a large campus network, showing that 15-25% of TCP connections have at least one TCP RST (reset). Similar results have also been observed from measurements of other Internet links. The results in this paper show that reset connections arise from local events such as network outages, attacks
Isoform Selectivity of Adenylyl Cyclase Inhibitors: Characterization of Known and Novel Compounds

Nine membrane-bound adenylyl cyclase (AC) isoforms catalyze the production of the second messenger cyclic AMP (cAMP) in response to various stimuli. Reduction of AC activity has well documented benefits, including benefits for heart disease and pain. These roles have inspired development of isoform-selective AC inhibitors, a lack of which currently limits exploration of functions and/or treatment of dysfunctions involving AC/cAMP signaling. However, inhibitors described as AC5- or AC1-selective have not been screened against the full panel of AC isoforms. We have measured pharmacological inhibitor profiles for all transmembrane AC isoforms. We found that 9-(tetrahydro-2-furanyl)-9H-purin-6-amine (SQ22,536), 2-amino-7-(furanyl)-7,8-dihydro-5(6H)-quinazolinone (NKY80), and adenine 9-β-d-arabinofuranoside (Ara-A), described as supposedly AC5-selective, do not discriminate between AC5 and AC6, whereas the putative AC1-selective inhibitor 5-[[2-(6-amino-9H-purin-9-yl)ethyl]amino]-1-pentanol (NB001) does not directly target AC1 to reduce cAMP levels. A structure-based virtual screen targeting the ATP binding site of AC was used to identify novel chemical structures that show some preference for AC1 or AC2. Mutation of the AC2 forskolin binding pocket does not interfere with inhibition by SQ22,536 or the novel AC2 inhibitor, suggesting binding to the catalytic site. Thus, we show that compounds lacking the adenine chemical signature and targeting the ATP binding site can potentially be used to develop AC isoform–specific inhibitors, and discuss the need to reinterpret literature using AC5/6-selective molecules SQ22,536, NKY80, and Ara-A.
Measurement of the azimuthal anisotropy for charged particle production in lead-lead collisions with the ATLAS detector

Differential measurements of charged particle azimuthal anisotropy are presented for lead-lead collisions at √ s NN = 2 . 76 TeV with the ATLAS detector at the LHC, based on an integrated luminosity of approximately 8 μ b − 1 . This anisotropy is characterized via a Fourier expansion of the distribution of charged particles in azimuthal angle relative to the reaction plane, with the coefﬁcients v n denoting the magnitude of the anisotropy. Signiﬁcant v 2 – v 6 valuesareobtainedasafunctionoftransversemomentum(0 . 5 < p T < 20GeV),pseudorapidity ( | η | < 2 . 5), and centrality using an event plane method. The v n values for n (cid:2) 3 are found to vary weakly with both η and centrality, and their p T dependencies are found to follow an approximate scaling relation, v 1 /nn ( p T ) ∝ v 1 / 2 2 ( p T ), except in the top 5% most central collisions. A Fourier analysis of the charged particle pair distribution in relative azimuthal angle ( (cid:3)φ = φ a − φ b ) is performed to extract the coefﬁcients v n,n = (cid:4) cos n(cid:3)φ (cid:5) . For pairs of charged particles with a large pseudorapidity gap ( | (cid:3)η = η a − η b | > 2) and one particle with p T < 3 GeV, the v 2 , 2 – v 6 , 6 values are found to factorize as v n,n ( p a T ,p b T ) ≈ v n ( p a T ) v n ( p b T ) in central and midcentral events. Such factorization suggests that these values of v 2 , 2 – v 6 , 6 are primarily attributable to the response of the created matter to the ﬂuctuations in the geometry of the initial state. A detailed study shows that the v 1 , 1 ( p aT ,p bT ) dataareconsistentwiththecombinedcontributionsfromarapidity-even v 1 andglobalmomentumconservation.A two-componentﬁtisusedtoextractthe v 1 contribution.Theextracted v 1 isobservedtocrosszeroat p T ≈ 1 . 0GeV, reaches a maximum at 4–5 GeV with a value comparable to that for v 3 , and decreases at higher p T .
The Datafied Society

As machine-readable data comes to play an increasingly important role in everyday life, researchers find themselves with rich resources for studying society. The novel methods and tools needed to work with such data require not only new knowledge and skills, but also a new way of thinking about best research practices. This book critically reflects on the role and usefulness of big data, challenging overly optimistic expectations about what such information can reveal, introducing practices and methods for its analysis and visualisation, and raising important political and ethical questions regarding its collection, handling, and presentation.
Secondary Control Scheme for Voltage Unbalance Compensation in an Islanded Droop-Controlled Microgrid

The concept of microgrid hierarchical control is presented recently. In this paper, a hierarchical scheme is proposed which includes primary and secondary control levels. The primary level comprises distributed generators (DGs) local controllers. The local controllers mainly consist of power, voltage and current controllers, and virtual impedance control loop. The central secondary controller is designed to manage the compensation of voltage unbalance at the point of common coupling (PCC) in an islanded microgrid. Unbalance compensation is achieved by sending proper control signals to the DGs local controllers. The design procedure of the control system is discussed in detail and the simulation results are presented. The results show the effectiveness of the proposed control structure in compensating the voltage unbalance.
Thermal Denaturation and Aggregation of Myosin Subfragment 1 Isoforms with Different Essential Light Chains

We compared thermally induced denaturation and aggregation of two isoforms of the isolated myosin head (myosin subfragment 1, S1) containing different “essential” (or “alkali”) light chains, A1 or A2. We applied differential scanning calorimetry (DSC) to investigate the domain structure of these two S1 isoforms. For this purpose, a special calorimetric approach was developed to analyze the DSC profiles of irreversibly denaturing multidomain proteins. Using this approach, we revealed two calorimetric domains in the S1 molecule, the more thermostable domain denaturing in two steps. Comparing the DSC data with temperature dependences of intrinsic fluorescence parameters and S1 ATPase inactivation, we have identified these two calorimetric domains as motor domain and regulatory domain of the myosin head, the motor domain being more thermostable. Some difference between the two S1 isoforms was only revealed by DSC in thermal denaturation of the regulatory domain. We also applied dynamic light scattering (DLS) to analyze the aggregation of S1 isoforms induced by their thermal denaturation. We have found no appreciable difference between these S1 isoforms in their aggregation properties under ionic strength conditions close to those in the muscle fiber (in the presence of 100 mM KCl). Under these conditions kinetics of this process was independent of protein concentration, and the aggregation rate was limited by irreversible denaturation of the S1 motor domain.
Financial Crises and the Success of Global Portfolio Management: A Study of the Middle East and North Africa

Our principal objective is to implement a conditional CAPM that, in addition to the global market risk, specifies the level of market integration, evaluates exchange rate risk, and accounts for local market risk. To investigate the potential for portfolio diversification for foreign investors in this region by examining the impact of financial crises on the evolution of national markets in the MENA region's financial integration with the global market as well as with the three selected developed markets, namely France, Great Britain, and the United State. In order to test a conditional version of De Santis and Gerard's ICAPM by admitting a specification of a multivariate GARCH process, this line of research has used a particular methodology (MGARCH).
Do individual programme effects exceed the costs? Norwegian evidence on long run effects of labour market training

Individual long run effects of a labour market training programme targeted at unemployed adults are evaluated by comparing mean post-training earnings for matched samples of participants and non-participants. Average training effects on the trained are positive and persistent over the posttraining period of 5 years. Participants without recent work experience, prior to the training, gain less. For participants with recent work experience the present value of the 5 years accumulated earnings effect exceeds the direct costs of the training.
Disneyland and Culture: Essays on the Parks and Their Influence

The overwhelming success of Disneyland, the world's first permanent, commercially viable theme park, sparked the creation of a number of other parks throughout the world, from Florida to Japan, France, and Hong Kong. Disneyland's impact is not confined merely to the theme park arena. These essays explore the far-reaching ideology unleashed by Disneyland. Topics include Disney's role in the creation of children's architecture; Frontierland as an allegorical map of the American West; the "cultural invasion of France" in Disneyland Paris; the politics of nostalgia; and "hyperurbanity" in the town of Celebration, Florida.
Research on the Economic Development Effect of Digital Economy

: The digital economy has gradually become an important driving force for economic development. We empirically tested the impact of the digital economy on economic development using inter provincial panel data from 2012 to 2018 in China. Research has found that the digital economy has had a significant positive impact on China's economic development, indicating that it has played a positive role in economic development and also reflecting the enormous opportunities that the digital economy has brought to China's economic development. Therefore, in the future, it is necessary to further improve the new digital infrastructure and strengthen the cultivation of digital information technology talents.
WETTING CONTROLLED PHASE TRANSITIONS IN TWO-DIMENSIONAL SYSTEMS OF COLLOIDS

The phase behavior of disk colloids, embedded in a two-dimensional fluid matrix that undergoes a first-order phase transition, is studied in the complete wetting regime where the thermodynamically metastable fluid phase is stabilized at the surface of the disks. In dilute collections of disks, the tendency to minimize the extent of the fluid-fluid interface and the extent of the unfavorable wetting phase in the system gives rise to aggregation phenomena and to separation of large domains of disks that have the characteristics of bulk colloidal phases. The conditions for phase transitions among cluster gas, liquid, and solid phases of the disk colloids are determined from the corresponding values of the disk chemical potential within an analytic representation of the grand partition function for the excess energy associated with a gas of disk clusters in the low-disk-density limit. The wetting effective-interface potential is combined with the disk interaction potential in associating an internal energy with each one of the clusters. The theory can thus be applied to any type of interaction potential among disks, provided that the free energy associated with the corresponding bulk colloidal phases is available. A phase diagram is calculated explicitly for the case of hard disks on the basis of an analytical approximation for the free energy of the hard disk fluid phase and the generalized effective liquid approximation for the free energy of the hard disk solid phase.
Socio-Economic Determinants for Adoption of Adaptation Strategies to Climate Change and Variability among Smallholder Farmers in Igambang’ombe, Sub-County, Kenya

Climate change and variability have been identified globally as a major challenge to food security especially in Arid and Semi-Arid lands (ASALs). Agriculture and smallholder farmers have also been identified as the most vulnerable, mainly due to the former being rain-fed and the latter having inadequate adaptive capacity to the dynamics of climate change and variability. This study, therefore, sought to determine the social-economic factors that influence the adoption of adaptation strategies for climate change and variability, among smallholder farmers in Igambang’ombe Sub-County, Tharaka Nithi County. A descriptive research design was applied. Systematic random sampling was used to select the respondents and a semi-structured questionnaire with open and closed-ended questions was used for data collection. Observations and interviews were carried out, while systematic random sampling was used to select the respondents. Correlation analysis was used to assess which socio-economic factors influenced the adoption of adaptation strategies to climate change and variability. Some of the adaptation strategies considered included; accessed weather information Ox-ploughing and herbicide use for preparation, terracing and intercropping, crop and variety diversification The study showed that age (42%), farmer’s farming experience (40%), and level of education of the household head (24%), were the key socio-economic factors influencing the adoption of adaptation strategies to climate change and variability. Adaptation of climate change and variability adaptation strategies was also associated to access and frequency of extension services. Access to farm subsidy and credit was also important. Farmers and agriculture stakeholders needed to upscale training, guided by specific socio-economic farmer characteristics.
Entorno extensible para la monitorización y detección de síntomas de depresión

Resumen La depresión es una enfermedad silenciosa que está aumentando de forma alarmante debido al ritmo de vida de la sociedad. Los propios śıntomas de la depresión hacen que los pacientes se enfrenten a barreras psicológicas que dificultan la búsqueda de tratamiento. Actualmente, los dispositivos móviles están siendo usados para monitorizar el comportamiento de las personas y, aśı, identificar si presentan distintas enfermedades. En este art́ıculo se presenta un conjunto de aplicaciones que detectan śıntomas de depresión de forma pasiva para el usuario, reduciendo los posibles obstáculos para la identificación de esta enfermedad. Estas aplicaciones han sido desarrolladas para que los datos monitorizados puedan ser reutilizados por otros sistemas, sin que ello conlleve un incremento en el consumo de recursos.
Properties of Whistler Waves’ Ducting in Plasmas With Systems of Small‐Scale Density Depletions

The ducting of whistler waves by systems of small‐scale field‐aligned plasma density depletions is studied. Similarly to our previous paper (Zudin et al., 2019, https://doi.org/10.1029/2019ja026637), we carry out analytical calculations and numerical simulations for the parameters of an active experiment in which very low frequency whistler waves emitted by a ground‐based transmitter at a frequency of 18 kHz were received onboard the DEMETER satellite at 700 km above the SURA heating facility. Random‐sized density depletions with a level around 10%–20% and perpendicular sizes ranging from 10 m up to about 300 m are considered. The properties of ducted waves are determined by the perpendicular size of individual depletions. Particularly, depletions with a width of more then d0 ∼ 100 m form separate ducting structures, that is, coupled waveguides capable of exchanging energy by means of mode overlap. Depletions with a width of less than d0 ∼ 100 m form a common waveguide structure, whose properties are equivalent to those of a wider irregularity with a smoothed density profile. Two important differences are revealed in ducting properties of density depletions compared to density enhancements considered in Zudin et al. (2019, https://doi.org/10.1029/2019ja026637). First, depletions support highly oblique Gendrin mode waves, rather than quasi‐longitudinal whistlers as in the case of density enhancements. Second, the characteristic perpendicular size d0 ∼ 100 m of density depletions separating the regimes of “coupled waveguides” and of “equivalent ducting structure” with smoothed density profile is by an order of magnitude smaller than for density enhancements of the same 10–20% relative level.
Liming effects on sulfentrazone availability in the profile of a Dusky Red Latosol and a Red Nitosol.

The objective of this work was to study a way to make available sulfentrazone applied to two soil classes, Dusk Red Latosol (LVdf) and Red Nitosol (NV), which were previously submitted to four liming levels. The sulfentrazone at 800 g/ ha of a.i. was applied on the top of PVC columns, containing the soils previously saturated to 65 % of field capacity (w/w). Daily rainfalls of 10 mm were simulated, until the index of 60 mm was reached, when the tubes were divided longitudinally and 5 sorghum (Sorghum bicolor) seeds were placed at the depths of 2.5, 7.5, 12.5, 17.5, 22.5, and 30.0 cm starting from the superior part of the tubes, and were thus maintained during 15 days, under controlled conditions, for the evaluation of seed germination and initial seedling growth. Morphophysiological changes that could be ascribed to sulfentrazone toxic effects and the length of the aerial part were evaluated to the last visible ligule of the seedlings. The seedlings aerial parts were ovendried at 70 oC for 96 h. The results showed that in the Dusk Red Latosol the different liming levels significantly affected height, survival and dry weight of the seedlings at the depth of 2.5 cm. When the Red Nitosol was used, the liming significantly affected seedling height and survival at the depth of 2.5 cm. When seedling weight was considered, this significant influence was detected up to 7.5 cm of depth. Additional keywords: Liming, herbicide, leaching, texture, pH, soil. Cientifica, Jaboticabal, v.35, n.2, p.106 114, 2007
Leading indicators of financial stress: a regime switching approach*

A lot of macroprudential research today focuses on quantifying the build - up of vulnerabilities in the financial system, as well as on quantifying risk materialization in the forms of financial stress that occurs in the system itself. However, there is still a lack of research linking the build - up of vulnerabilities to the risk materialization approach. This research tries to fill that gap. Focus is put on the prediction of the probability of (re)entering high financial stress (via a large set of cyclical risk accumulation indicators). The regime - switching models ’ results indicate that some credit specifications, house price dynamics, and debt burden could be best monitored for the case of Croatian data.
Examples of renormalized SDEs

Citation for published version: Bruned, Y, Chevyrev, I & Friz, PK 2018, Examples of renormalized SDEs: SPDERF 2016: Stochastic Partial Differential Equations and Related Fields. in International Conference on Stochastic Partial Differential Equations and Related Fields . Springer Proceedings in Mathematics & Statistics book series (PROMS, volume 229), Springer, Cham. DOI: 10.1007/978-3-319-74929-7_19
Measuring the strength of maternal, newborn and child health care implementation and its association with childhood mortality risk in three rural districts of Tanzania

This observational cohort study explores the association between maternal, newborn and child health care implementation strength and child survival in rural Tanzania from 2011-2015. We used data from a 2011 service availability and readiness assessment that quantified primary health care facilities ability to implement maternal, newborn and child health services and a population-level household survey that measured the utilization of such services to develop domain-specific summary measures of the effective coverage of facility-based maternal, newborn and child health care. We reduced domain specific effective coverage scores into fewer, independent scales of implementation strength using principal components analysis, and integrated them into gradients of the collective implementation strength exerted by groups of facilities on villages they served using Bayesian mixed effects models. We linked these scales to longitudinal data on the survival of children that were born in the catchment areas of the surveyed health facilities during the assessment period and followed up until December 31, 2015. We fit survival time models to estimate the relationship between implementation strength and child mortality. Increases in the implementation strength gauged by our first scale, which represented general facility readiness and the provision of antenatal, postnatal, and early childhood preventive services, were associated with child mortality risks that were, on average, 0.62 times lower. Increases in implementation strength gauged by our second scale, which represented sick childcare service provision, were associated with child mortality risks that were, on average, 0.56 times lower. We detected no significant child mortality response to our third scale, which represented intrapartum care provision. The findings suggest that strong implementation of antenatal, postnatal, early childhood preventive services and sick child care can accelerate child mortality reduction and that routine data on service availability and readiness can be used to measure health systems strengthening and its impacts.
Extracción y purificación de antocianinas a partir de residuos de uva

La industria vinicola genera unos residuos de la uva, de los que se pueden recuperar o derivar productos valiosos como etanol, acido citrico, tartratos, antocianinas y aceite. En este trabajo se estudia la recuperacion de antocianinas, pigmentos de gran aplicacion en la industria alimentaria como aditivos naturales. Se han aplicado tecnicas de extraccion solido/liquido, utilizando disolventes extractantes formados por agua y alcohol con acidos. Se ha analizado la influencia de variables de operacion tales como relacion disolvente/solido, pH, temperatura, humedad, metodo de agitacion y forma de contacto; extraccion simple y multiple. Tambien se ha disenado y puesto a punto una columna para llevar a cabo la extraccion de antocianinas de forma continua. Se ha intentado aumentar la cantidad de antocianinas recuperadas degradando parcialmente el residuo antes de la extraccion, mediante un ataque con enzimas del grupo de las celulasas. Se ha puesto a punto un metodo para purificar y concentrar los extractos obtenidos, mediante neutralizacion de acido tartarico, filtracion de tartrato acido de potasio y destilacion a vacio de metanol. Por utlimo se ha disenado una planta piloto para la obtencion de concentrado de antocianinas en la que se recuperarian y reutilizarian todos los reactivos.
Multi-patch matching for person re-identification

Recognizing a target object across non-overlapping distributed cameras is known in the computer vision community as the problem of person re-identification. In this paper, a multi-patch matching method for person reidentification is presented. Starting from the assumption that: the appearance (clothes) of a person does not change during the time of passing in different cameras field of view , which means the regions with the same color in target image will be identical while crossing cameras. First, we extract distinctive features in the training procedure, where each image target is devised into small patches, the SIFT features and LAB color histograms are computed for each patch. Then we use the KNN approach to detect group of patches with high similarity in the target image and then we use a bi-directional weighted group matching mechanism for the re-identification. Experiments on a challenging VIPeR dataset show that the performances of the proposed method outperform several baselines and state of the art approaches.