Miracle-dz/UniFAR-FTUs huggingface dataset:
A VLA Survey of the Three Clusters of Galaxies 0016+16, Abell 665, and Abell 2218

The VLA was used to survey the fields of the three clusters of galaxies 0016 + 16, Abell 665, and Abell 2218 for radio sources that might contaminate observations of the Sunyaev-Zel'dovich effect. Surveys at 1440 and 4860 MHz covering the full fields were followed by pointed observations at 14,940 MHz for the brighter sources. Several of the sources are significant contaminants of Sunyaev-Zel'dovich observations. Corrections for the contaminating sources, and the best observing locations in the three clusters, may be found on the basis of the survey; as an example, the corrections to the results of Birkinshaw et al. (1984) are calculated. Each of the clusters appears to possess a faint central steep-spectrum extended source. It is speculated that the presence of a radio halo source is correlated with the existence of a strong Sunyaev-Zel'dovich effect. 25 refs.
X-ray observations of GX 1 + 4 with the monitor proportional counter on board the Einstein Observatory

The results of X-ray observations of GX 1 + 4 with the monitor proportional counter on board the Einstein Observatory (HEAO 2) are presented. Using data from the time interval processor, the value of the approximately 2 minute pulse period at the time of the observations was determined. Previous determinations are discussed, along with evidence for a suggested value of approximately 4 minutes for the pulse period. The phase of first harmonic of the Fourier decomposition of pulse profile is stable within its errors but the phases of higher harmonics are not. The spin-up time scale is determined to be approximately 40 years. 24 references.
What can be gained through peer supervision?

Aims:This article reports on the practical venture we have undertaken as two trainee educational psychologists (TEPs) developing a peer supervision group to supplement professional supervision provided on practice placements. This personal and reflective journey aims to explore what can be gained through peer supervision.Rationale:Professional supervision is a requirement for the profession of educational psychology (Health and Care Professions Council, 2012). Quality supervision ensures high practice standards for service users and maintains the development and well-being of supervisees (Dunsmuir & Leadbetter, 2010). This article explores how peer supervision can help fulfil these requirements.Method:Theory and research are discussed in relation to the development of our peer supervision group. Through an enquiry-based learning (EBL) approach (Kahn & O’Rourke, 2005) we identify the positive outcomes of our peer supervision group.Findings:These gains are broadly grouped around ‘development of skills and moving forward’ and ‘sharing, supporting and well-being’. The EBL process also recognised the importance of ‘dynamics’ in peer supervision. Critical discussion of these outcomes is exemplified through case work in practice.Conclusions and limitations:This article presents personal experiences of our peer supervision group. We believe that the benefits we have gained from the process demonstrates the usefulness of peer supervision for the practice of trainees and recently qualified EPs, as well as more experienced professionals. It is hoped that by addressing power differentials and developing a sense of peerness, we can continue to gain from peer supervision in our TEP practice and beyond.
Wnt/β-Catenin Signaling and Resistance to Immune Checkpoint Inhibitors: From Non-Small-Cell Lung Cancer to Other Cancers

Lung cancer is the leading cause of cancer-related deaths worldwide. The standard of care for advanced non-small-cell lung cancer (NSCLC) without driver-gene mutations is a combination of an anti-PD-1/PD-L1 antibody and chemotherapy, or an anti-PD-1/PD-L1 antibody and an anti-CTLA-4 antibody with or without chemotherapy. Although there were fewer cases of disease progression in the early stages of combination treatment than with anti-PD-1/PD-L1 antibodies alone, only approximately half of the patients had a long-term response. Therefore, it is necessary to elucidate the mechanisms of resistance to immune checkpoint inhibitors. Recent reports of such mechanisms include reduced cancer-cell immunogenicity, loss of major histocompatibility complex, dysfunctional tumor-intrinsic interferon-γ signaling, and oncogenic signaling leading to immunoediting. Among these, the Wnt/β-catenin pathway is a notable potential mechanism of immune escape and resistance to immune checkpoint inhibitors. In this review, we will summarize findings on these resistance mechanisms in NSCLC and other cancers, focusing on Wnt/β-catenin signaling. First, we will review the molecular biology of Wnt/β-catenin signaling, then discuss how it can induce immunoediting and resistance to immune checkpoint inhibitors. We will also describe other various mechanisms of immune-checkpoint-inhibitor resistance. Finally, we will propose therapeutic approaches to overcome these mechanisms.
Hyperhomocysteinemia in Patients with Newly Diagnosed Primary Hypertension in Can Tho City, Vietnam

Background: Elevated levels of blood total homocysteine is one of the cardiovascular risk factors in hypertensive patients. Objectives: Determine the prevalence of hyperhomocysteinemia and its associated factors in newly diagnosed primary hypertension patients. Materials and methods: A cross-sectional descriptive study on 105 patients with newly diagnosed primary hypertension at Can Tho University of Medicine and Pharmacy Hospital from May 2017 to May 2018. Total homocysteine levels and related factors were collected at the study time. Results: The mean plasma total homocysteine level was 16.24 ± 4.49 µmol/L. There were 78 patients with elevated plasma total homocysteine levels ≥15 µmol/L, accounting for 74.3% of all patients. Being elderly, gender, hypertension stage, and diabetes were factors associated with hyperhomocysteinemia (p < 0.05). Total homocysteine levels were positively correlated with SBP, DBP, and age with r(SBP) = 0.696, r(DBP) = 0.585, and r(age) = 0.286. Conclusion: Research on the subpopulation of Vietnamese people shows that hyperhomocysteinemia is common in patients with newly diagnosed primary hypertension, and high blood total homocysteine levels are often related to age, sex, hypertension stage, and diabetes.
Underwater Sounds from the Blue Whale, Balaenoptera musculus

Powerful low‐frequency sounds were recorded from blue whales, Balaenoptera musculus, off the Chilean coast. These three‐part sounds lasted about 36.5 sec, and ranged in frequency from 12.5 to 200 Hz. The sounds occurred in a repetitive pattern that was interrupted as the whale came to the surface to breathe. We estimated that these moanings, in a 14‐ to 222‐Hz band, were 188 dB re 1 μN/m2 (= 88 dB re 1 μbar) at 1 m. They are the most powerful sustained utterances known from whales or any other living source. This finding is especially noteworthy because it is doubtful if these animals, the largest ever to inhabit the earth, will survive man's overharvest.
Hamiltonian theory of relativistic magnetohydrodynamics with anisotropic pressure

This Brief Communication introduces a special relativistic extension of ideal magnetohydrodynamics having anisotropic pressure, and provides its Hamiltonian formulation in a fixed inertial frame. The nonrelativistic limit of this theory recovers the ‘‘double adiabatic’’ hydromagnetic equations of Chew, Goldberger, and Low [Proc. R. Soc. London Ser. A 236, 112 (1956)]. For isotropic pressure distribution the equations and Hamiltonian structure reduce to the usual theory of relativistic magnetohydrodynamics. The Poisson bracket for the system is not symplectic. Rather, it is dual to a Lie algebra of semidirect‐product type.
In Vitro Metabolism and CYP-Modulating Activity of Lavender Oil and Its Major Constituents

The application of essential oils has historically been limited to topical (massage therapy) and inhalational (aromatherapy) routes of administration. More recently, however, evaluation of the therapeutic effects of essential oils has expanded to include the oral route of administration, which increases the herb–drug interaction potential. The purpose of this study was to evaluate the herb–drug interaction potential of lavender essential oil and two of its primary phytoactive constituents, namely linalool and linalyl acetate. The metabolic stability of linalool and linalyl acetate was determined in human liver microsomes (HLM) and S9 fractions by quantitative analysis using UPLC-MS/MS system. Linalool was metabolically unstable in HLM and S9 fractions with an intrinsic clearance of 31.28 mL·min−1·kg−1, and 7.64 mL·min−1·kg−1, respectively. Interestingly, it was observed that linalyl acetate converted to linalool both in HLM and S9 fractions. Lavender oil showed weak inhibitory effect on the catalytic activity of CYP3A4 and CYP1A2 enzymes (IC50 12.0 and 21.5 µg/mL). Linalyl acetate inhibited CYP3A4 (IC50 4.75 µg/mL) while linalool did not show any inhibitory effect on any of the enzymes. The lavender oil and its constituents did not activate PXR to a considerable extent, and no activation of AhR was observed, suggesting a lack of potential to modify the pharmacokinetic and pharmacodynamic properties of conventional medications if used concurrently.
Proceedings of Meetings on Acoustics

One of the most striking external features of a modern trombone is its wide and rapidly flaring bell. The bore profile of this final section of the instrument influences its musical behaviour in a number of different ways, since it determines both the strength of the acoustical feedback from the instrument to the lips of the player and the nature of the radiated sound field. These effects have been explored in an experimental study in which a number of trombones have been progressively modified by the removal of annular sections of the bells. Measurements of input impedance, transfer function and directivity of radiated sound are presented, and the implications for the timbre and playability of the instruments are discussed.
Multilesion Segmentations in Patients with Intracerebral Hemorrhage: Reliability of ICH, IVH and PHE Masks

Background and Purpose: Fully automated methods for segmentation and volume quantification of intraparenchymal hemorrhage (ICH), intraventricular hemorrhage extension (IVH), and perihematomal edema (PHE) are gaining increasing interest. Yet, reliabilities demonstrate considerable variances amongst each other. Our aim was therefore to evaluate both the intra- and interrater reliability of ICH, IVH and PHE on ground-truth segmentation masks. Methods: Patients with primary spontaneous ICH were retrospectively included from a German tertiary stroke center (Charité Berlin; January 2016–June 2020). Baseline and follow-up non-contrast Computed Tomography (NCCT) scans were analyzed for ICH, IVH, and PHE volume quantification by two radiology residents. Raters were blinded to all demographic and outcome data. Inter- and intrarater agreements were determined by calculating the Intraclass Correlation Coefficient (ICC) for a randomly selected set of patients with ICH, IVH, and PHE. Results: 100 out of 670 patients were included in the analysis. Interrater agreements ranged from an ICC of 0.998 for ICH (95% CI [0.993; 0.997]), to an ICC of 0.979 for IVH (95% CI [0.984; 0.993]), and an ICC of 0.886 for PHE (95% CI [0.760; 0.938]), all p-values < 0.001. Intrarater agreements ranged from an ICC of 0.997 for ICH (95% CI [0.996; 0.998]), to an ICC of 0.995 for IVH (95% CI [0.992; 0.996]), and an ICC of 0.980 for PHE (95% CI [0.971; 0.987]), all p-values < 0.001. Conclusion Manual segmentations of ICH, IVH, and PHE demonstrate good-to-excellent inter- and intrarater reliabilities, with the highest agreement for ICH and IVH and lowest for PHE. Therefore, the degree of variances reported in fully automated quantification methods might be related amongst others to variances in ground-truth masks.
In-session Behaviour Incompatible with Goals (BIG problems) within coaching

The concept ofBehaviourIncompatible withGoals (BIG problems) has been developed for the field of coaching based on Linehan’s original work on Therapy-Interfering-Behaviour used within Dialectical Behaviour Therapy. Behaviour Incompatible with Goals can prevent coachees from making progress in coaching. Both the practitioner and coach can have BIG problems. This article covers how to deal with BIG problems that occur in-session.
Pendampingan dan Pemanfaatan Marketplace Sebagai Digital Marketing Kerajinan Usaha Kreatif Aceh

Online marketing, or what is known as marketplaces, has opened a new paradigm for marketing and launching products quickly and efficiently compared to the traditional method of selling through stores or point of sale. The key to online marketing success lies in the ability to first look at what and how your competitors operate and attract buyers with products and promotions that are different from other businesses his players. This is because the creative artisanal marketing strategies of various Aceh souvenirs, on average, are waiting for orders from merchants and buyers with traditional patterns. The purpose of this service activity is to advocate, advise and socialize the use of marketplaces in Aceh, especially in Sigli City, Pidie District, Aceh State, by creating a web marketplace for creative crafts sector. is to empower the craftsman and his MSMEs. The method of carrying out activities consists of three phases. Seminars, workshops, monitoring and evaluation. As a result of this activity, a web marketplace digi-expo.mwebs. id for online marketing through internet for creative craft industry in Aceh was implemented to increase the revenue from online sales of products.
The spectral flattening of the low-energy component in gamma-ray bursts

Observations from BATSE show that the spectra of gamma-ray bursts are very wide, which cannot be described by a simple law. The distribution of the peak energy E(p) [defined as the maximum of the E(gamma)(2)N(E(gamma)) spectrum], and of the spectral indices below and above E(p), is wide. In particular, the slope below E(p) lies mainly between 0.5 and 1, which is inconsistent with the 4/3 predicted by the simple synchrotron radiation spectrum. Here we discuss the emission model for gamma-ray bursts based on the shock model proposed by Meszaros & Rees. We find that the synchrotron radiation of relativistic electrons accelerated by a strong shock, together with the finite lifetime of synchrotron radiation and the non-uniform magnetic field distribution, can explain the gamma-ray burst spectra, and the spectral index below the peak energy E(p) can be flattened by the non-uniform magnetic field distribution; this flattening is insensitive to the specific form of the magnetic field variance. Furthermore, the peak energy E(p) proportional to Gamma(4) is sensitively dependent on the bulk Lorentz factor.
Natural radionuclides and 137Cs in moss and lichen in eastern Serbia

The paper presents the results of radionuclides determination in moss (Homolothecium sp., Hypnum Cupressiforme sp., and Brachythecium sp.) and lichen (Cladonia sp.) sampled in the region of Eastern Serbia during 1996-2010. The activities in moss are in the range of 100-500 Bq/kg d. w. for 40K, and 5-50 Bq/kg d. w. for 226Ra and 232Th, while the “soil-to-moss” transfer factors are 0.45 for 40K, 3 for 226Ra, and 0.3 for 232Th. The spatial distribution of the 137Cs activities is highly non-uniform; some values reach 500 Bq/kg d. w. , with less than 10% of the samples, mainly the ones taken prior to 2000, with the activity above 1000 Bq/kg d. w. The variations in the content of natural radionuclides among the moss species are not significant. The frequency pattern of the activities of natural radionuclides in lichen is similar to the one in moss, but the activities in lichen are to some extent lower. The mean activity of 137Cs in lichen is below 400 Bq/kg d. w. The mean activities of 7Be in moss and lichen sampled in 2006 and 2008 are in the range of 41-122 Bq/kg d. w. , with pronounced variations between the sampling sites.
Mapping Population Distribution with High Spatiotemporal Resolution in Beijing Using Baidu Heat Map Data

Population distribution data with high spatiotemporal resolution are of significant value and fundamental to many application areas, such as public health, urban planning, environmental change, and disaster management. However, such data are still not widely available due to the limited knowledge of complex human activity patterns. The emergence of location-based service big data provides additional opportunities to solve this problem. In this study, we integrated ambient population data, nighttime light data, and building volume data; innovatively proposed a spatial downscaling framework for Baidu heat map data during work time and sleep time; and mapped the population distribution with high spatiotemporal resolution (i.e., hourly, 100 m) in Beijing. Finally, we validated the generated population distribution maps with high spatiotemporal resolution using the highest-quality validation data (i.e., mobile signaling data). The relevant results indicate that our proposed spatial downscaling framework for both work time and sleep time has high accuracy, that the distribution of the population in Beijing on a regular weekday shows “centripetal centralization at daytime, centrifugal dispersion at night” spatiotemporal variation characteristics, that the interaction between the purpose of residents’ activities and the spatial functional differences leads to the spatiotemporal evolution of the population distribution, and that China’s “surgical control and dynamic zero COVID-19” epidemic policy was strongly implemented. In addition, our proposed spatial downscaling framework can be transferred to other regions, which is of value for governmental emergency measures and for studies about human risks to environmental issues.
The Ultraviolet Light Curve of LMC X‐4: X‐Ray Heating of the O Star and Accretion Disk

We present an archival study of ultraviolet spectra of the X‐ray binary LMC X‐4 obtained with the IUE satellite. We fit these spectra with models that incorporate the X‐ray heating of the O star and accretion disk. A systematic analysis of the UV continuum confirms the general picture of an O star that fills its Roche lobe and is heated by X‐rays from the neutron star. About 5% of the UV emission arises in an accretion disk, which may precess with a ≈30 day period. We measure the mass transfer through the accretion disk and attempt to relate this quantity to changes in the pulse period and disk precession. The principal source of uncertainty in our model results from the choice of the 30 day disk precession ephemeris. We examine the RXTE All‐Sky Monitor data for LMC X‐4 to attempt to clarify the variability of the 30 day period. We find no evidence for additional heating of the O star or disk as the result of an X‐ray flare observed with IUE and EXOSAT in 1983.
Rotationally excited HD toward Zeta Ophiuchi

The column density of rotationally excited HD toward zeta Oph has been measured, giving 0.15 +- 0.02 (1 sigma) for the ratio in J=1 to J=0. Distorted-wave Borne approximation calculations of the collisional excitation cross sections are given, and the effects of UV pumping on the population in J=1 are derived. A new analysis of the H/sub 2/ population in J=6 shows that the UV energy density is 2.4 x 10/sup -16/ ergs cm/sup -3/ A/sup -1/ at 1000 A. The cloud is about 28 pc from the star. The two-component model by Black and Dalgarno with densities of 500 and 2500 hydrogen nuclei cm/sup -3/ gives exactly the observed HD in J=1.
A Novel Dense-Attention Network for Thick Cloud Removal by Reconstructing Semantic Information

The presence of thick clouds in single optical images shows the contamination of interesting objects. Besides, the difficulty of thick cloud removal is mainly the restoration of the weak boundary information from cloud-contaminated areas. Recently, many deep-learning-based frameworks were applied for cloud removal by obtain the related semantic information from the weak boundary information. However, the large-size cloud-contaminated areas lead to the artificial textures in the resulting images. Thus, obtaining the optimal semantic information from finite boundary information is the key to solve this problem. In this work, we design a deep-learning framework for cloud removal, especially large-size clouds removal (i.e., more than 30% coverage of the whole image). First, we design a cloud location model (CLM), which adopted the fully convolutional network to locate the cloud. Second, desired by theory of the coarse-to-fine restoration, we build a dense-attention network (termed as DANet) for restoring cloud contaminated areas. In the DANet, we design a dense block into the coarse network for training the features of restoring directions of each pixel from the weak boundary information. Furthermore, a contextual attention module is built into refinement network for restoring contaminated areas relying on the semantic relationship between the background and foreground information. Compared with the state-of-the-art methods, the proposed DANet achieved greater removal performances and reconstruct more natural image textures.
Factors influencing knowledge of synthetic cannabinoids: Study conducted among future healthcare professionals

Introduction: Although the consumption of synthetic cannabinoids (SC) has become more and more widespread recently, future healthcare professionals, according to the currently available curriculum, receive minimal information about diagnosis and treatment thereof. Aim: The main goal is to assess the level of knowledge of students of health professions about SC and examine the factors that influence that knowledge. Material and methods: A cross-section academic study was conducted among 510 students of medicine, dentistry and pharmacy at the Faculty of Medicine, University of Novi Sad, Serbia, during 2017 using a structured questionnaire. Results: Forty-nine percent of students answered positively to the question if they knew what SCs were, whereas when they were offered three definitions regarding SCs-92.2% gave the correct answer, with male students demonstrating a better knowledge than female ones (p=0.014). There was no correlation between previous knowledge about SCs and professional qualifications of the student's parents (p=0.953 mother, p=0.500 father) or the student's social media profile existence (p=0.057). Pharmacy students showed better previous knowledge about SCs in comparison with students of other courses (p=0.000) as well as the final year students when compared to those from the 1 st and 2 nd year of study (p=0.000). The repetition of a year level did not affect student's knowledge (p=0.616). Students with experience in alcohol usage showed better previous knowledge of SCs in comparison with alcohol non-users (p=0.008). However, most of the respondents answered "do not know" on the majority of statements about SCs offered. Conclusion: Superficiality in students' knowledge and insufficiency of formal education contributes to the necessity for revising curriculum regarding SCs for future health care professionals.
The 'fitting problem' in cosmology

This paper considers the best way to fit an idealised exactly homogeneous and isotropic universe model to a realistic ('lumpy') universe; whether made explicit or not, some such approach of necessity underlies the use of the standard Robertson-Walker models as models of the real universe. Approaches based on averaging, normal coordinates and null data are presented, the latter offering the best opportunity to relate the fitting procedure to date obtainable by astronomical observations.