Miracle-dz/UniFAR-FTUs huggingface dataset:
Whether 3D Object is Copyright Protected? Controlled Object Identification in Additive Manufacturing

Additive manufacturing has opened the possibility of printing a 3D object by just having a blueprint and a 3D printer. This advent in technology has brought a cybersecurity challenge. This brings up a challenge to detect objects, henceforth called controlled objects (COs) that potentially infringe upon laws, authorship rights, and other legal constraints. It is desirable to detect the COs before starting the 3D printing process to prevent legal consequences. We propose a method for identification of COs in 3D print job based on application of 3D object descriptors/fingerprints. These descriptors reflect different properties of a 3D object design and identify whether the object is controlled or not. We consider only technical objects when the blueprint cannot change a lot. We propose a set of descriptors to efficiently store the information about the blueprint, and to make an effective search in the database of COs represented by their descriptors.
PHYTOCHEMICAL ANALYSIS AND ANTIOXIDANT ACTIVITY OF AMUKKARA THAILAM

Traditional medicine has been used for thousands of years to treat and prevent diseases plays an integral role in primary health care. The scientific analysis of Amukkara Thailam formulated from the polyherbs showed the presence of alkaloid, steroid, phenol, tannin, amino acid and antioxidant potential of 59.96 ± 0.011µg/ml to 81.41 ± 0.011 µg/ml showed the effect of medicine .
Genetic and functional characterization of Caenorhabditis elegans srf-3, a gene involved in regulating surface antigenicity

The widespread emergence of pathogens resistant to the majority of available antibiotics makes it necessary to find new ways to combat the corresponding microorganisms. Adaptive immunity is specific to vertebrates but the mechanisms of innate immunity are ancient and highly conserved during evolution. Therefore it is reasonable to use model organisms to study the molecular mechanisms of host defence and the corresponding mechanisms of pathogenicity. Microbacterium nematophilum adheres to the rectum of a Caenorhabditis elegans animal inducing a localized non-lethal response that causes swelling of the underlying hypodermal tissue. The aim of this thesis was to gain a first insight into the molecular mechanisms underlying the resistance of srf-3 animals to the bacterial pathogens Microbacterium nematophilum and Yersinia pestis/pseudotuberculosis. M. nematophilum adheres to the cuticle of wild type animals but fails to adhere to the surface of srf-3 worms. This is a novel type of resistance because pathogens like P. aeruginosa or Salmonella typhimurium do not adhere to the cuticle but kill C. elegans by colonization and accumulation in the intestine. Molecular cloning of srf-3 showed that this gene codes for a type III transmembrane protein similar to the family of UDP-galactose transporters. Expression analysis revealed that SRF-3 is expressed in a set of active secretory cells consistent with a function of this gene in cuticle or surface modification. A functional characterization of SRF-3 revealed that this protein can function as a nucleotide sugar transporter. The protein showed multisubstrate specificity capable of translocating UDP-galactose and UDP-N-acetylglucosamine in vitro as judged by transport assays done with Golgi/ER enriched vesicles, as well as in vivo, as shown by the phenotypic correction of mutants defective in UDP-galactose or UDP-N-acetylglucosamine transport. The data presented in this thesis emphasize the importance of glycosylation in regulating the surface antigenicity of C. elegans. This can help to understand the process of pathogen adherence, the first step in the establishment of an infection, as well as how parasitic nematodes modulate the surface in order to escape the host response.
Crystal structure of Mycobacterium tuberculosis FadB2 implicated in mycobacterial -oxidation

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of Birmingham Crystal structure of Mycobacterium tuberculosis FadB2 implicated in mycobacterial -oxidation.

The intracellular pathogen Mycobacterium tuberculosis is the causative agent of tuberculosis, which is a leading cause of mortality worldwide. The survival of M. tuberculosis in host macrophages through long-lasting periods of persistence depends, in part, on breaking down host cell lipids as a carbon source. The critical role of fatty-acid catabolism in this organism is underscored by the extensive redundancy of the genes implicated in (cid:2) -oxidation ( (cid:2) 100 genes). In a previous study, the enzymology of the M. tuberculosis l -3-hydroxyacyl-CoA dehydrogenase FadB2 was characterized. Here, the crystal structure of this enzyme in a ligand-free form is reported at 2.1 A˚ resolution. FadB2 crystallized as a dimer with three unique dimer copies per asymmetric unit. The structure of the monomer reveals a dual Rossmann-fold motif in the N-terminal domain, while the helical C-terminal domain mediates dimer formation. Comparison with the CoA- and NAD + -bound human orthologue mitochondrial hydroxyacyl-CoA dehydrogenase shows extensive conservation of the residues that mediate substrate and cofactor binding. Superposition with the multi-catalytic homo-logue M. tuberculosis FadB, which forms a trifunctional complex with the thiolase FadA, indicates that FadB has developed structural features that prevent its self-association as a dimer. Conversely, FadB2 is unable to substitute for FadB in the tetrameric FadA–FadB complex as it lacks the N-terminal hydratase domain of FadB. Instead, FadB2 may functionally (or physically) associate with the enoyl-CoA hydratase EchA8 and the thiolases FadA2, FadA3, FadA4 or FadA6 as suggested by interrogation of the STRING protein-network database.
Cardiovascular Disease in Women Clinical Perspectives

Cardiovascular disease (CVD) remains the leading cause of death in women and, according to the most recently released United States statistics, accounted for 398 086 female deaths in 2013. For the past 3 decades, dramatic declines in heart disease mortality for both men and women have been observed, especially in the >65 years age group. However, recent data suggest stagnation in the improvements in incidence and mortality of coronary heart disease, specifically among younger women (<55 years). It is imperative that we understand the mechanisms that contribute to worsening risk factor profiles in young women to reduce future atherosclerotic cardiovascular disease (ASCVD) morbidity and mortality. Increased recognition of the prevalence of traditional ASCVD risk factors, and their differential impact in women, as well as emerging, nontraditional risk factors unique to or more common in women, contribute to new understanding of mechanisms leading to these worsening outcomes for women (Figure 1). Finally, diagnosis of acute coronary syndromes (ACS) is often challenging in women, especially young women, and it is important to recognize differences in the signs and symptoms at presentation to improve patient management and outcomes. Awareness of CVD as the primary cause of mortality in women has been slowly increasing. In 1997, only 30% of American women surveyed were aware that CVD was the leading cause of death in women; this increased to 54% in 2009 and has subsequently plateaued when last surveyed in 2012. Women are less likely to receive preventive treatment or guidance, such as lipid-lowering therapy, aspirin (ASA), and therapeutic lifestyle changes, than are men at similar ASCVD risk. When medications are prescribed, treatment is less likely to be aggressive or to achieve optimal effects, for example, women with hypertension are less likely to have their blood pressure (BP) at goal, and hyperlipidemic women, especially those with coexisting diabetes mellitus (DM), are less likely to be treated with statins to lower low-density Review
A randomized controlled trial of two strategies to implement active sick leave for patients with low back pain.

STUDY DESIGN Cluster randomized controlled trial. OBJECTIVE To evaluate the effectiveness of two strategies to improve the use of active sick leave (ASL) for patients with low back pain. SUMMARY OF BACKGROUND DATA ASL is a public sickness benefit scheme offered to promote early return to modified work for temporarily disabled workers. It was poorly used, and the authors designed two community interventions to strengthen the implementation of ASL based on the results of a study of barriers to use among back pain patients, employers, general practitioners (GPs), and local National Insurance Administration staff. METHODS Sixty-five municipalities in three counties in Norway, randomly assigned to a passive intervention, a proactive intervention, or a control group. The interventions were targeted at patients on sick leave for low back pain for more than 16 days (n = 6176), their GPs, employers, and local insurance officers. The passive intervention included reminders about ASL on the sick leave form that GPs must complete, a standard agreement to facilitate ASL, targeted information, and a desktop summary for GPs of clinical practice guidelines for low back pain, emphasizing the importance of advice to stay active. The proactive intervention included these elements plus a resource person to facilitate the use of ASL and a continuing education workshop for GPs. The main outcome measure reported here is the proportion of eligible patients that used ASL. RESULTS ASL was used significantly more in the proactive intervention municipalities (17.7%) compared with the passive intervention and control municipalities (11.5%, P = 0.018). CONCLUSIONS A passive intervention that addressed identified barriers to the use of ASL did not increase its use. Although modest, a proactive intervention did increase its use. The main impact of the intervention was through direct contact and motivating telephone calls to patients. To the extent that GPs' practice was changed, it was either patient mediated or by patients bypassing their GP.
Editorial: Obesity and cancer: update on etiology, molecular biomarkers and biotargets, clinical strategies, and epidemiology

COPYRIGHT © 2023 Surmacz, Guarnotta and Reagan. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. TYPE Editorial PUBLISHED 14 August 2023 DOI 10.3389/fendo.2023. 1258994
Data & Channel Efficient Vision Transformer

In order to improve the accuracy of the ViT architecture in image recognition tasks, this paper proposes a Transformer-based DNN applied to image classifier called Data and Channel efficient vision Transformer network by extracting image channel information. Furthermore, a method to avoid overfitting is proposed called Entropy Increase for information of image Edge and Noise Lay-over for information of image Edge in this paper. Through a series of experiments, this paper compares the accuracy of the model with ViT and the traditional convolutional neural network structures in image classification tasks, and evaluates the effectiveness of the two image preprocessing algorithms on the model and the convolutional neural network model. It turns out that the accuracy of this model is about 2% higher than other ViT-based DNNs.
Laboratory investigation of photochemical oxidation of organic aerosol from wood fires 2: analysis of aerosol mass spectrometer data

Abstract. Experiments were conducted to investigate the effects of photo-oxidation on organic aerosol (OA) in dilute wood smoke by exposing emissions from soft- and hard-wood fires to UV light in a smog chamber. This paper focuses on changes in OA composition measured using a unit-mass-resolution quadrupole Aerosol Mass Spectrometer (AMS). The results highlight how photochemical processing can lead to considerable evolution of the mass, volatility and level of oxygenation of biomass-burning OA. Photochemical oxidation produced substantial new OA, more than doubling the OA mass after a few hours of aging under typical summertime conditions. Aging also decreased the volatility of the OA and made it progressively more oxygenated. The results also illustrate strengths of, and challenges with, using AMS data for source apportionment analysis. For example, the mass spectra of fresh and aged BBOA are distinct from fresh motor-vehicle emissions. The mass spectra of the secondary OA produced from aging wood smoke are very similar to those of the oxygenated OA (OOA) that dominates ambient AMS datasets, further reinforcing the connection between OOA and OA formed from photo-chemistry. In addition, aged wood smoke spectra are similar to those from OA created by photo-oxidizing dilute diesel exhaust. This demonstrates that the OOA observed in the atmosphere can be produced by photochemical aging of dilute emissions from different types of combustion systems operating on fuels with modern or fossil carbon. Since OOA is frequently the dominant component of ambient OA, the similarity of spectra of aged emissions from different sources represents an important challenge for AMS-based source apportionment studies.
Tumor necrosis factor-α and interleukin-4 gene polymorphisms in Chinese patients with gout

Objective The purpose of this study was to examine whether polymorphisms of interleukin-4 (IL-4) (promoter-590 and intron 3) and tumor necrosis factor-α (TNF-α) promoter-308 genes are markers of susceptibility to or clinical manifestations of gout in
Public Relations: Strategies and Tactics

Part 1 Role Chapter 1 What Is Public Relations? Chapter 2 The Evolution of Public Relations Chapter 3 Ethics and Professionalism Chapter 4 Public Relations Departments and Firms Part 2 Process Chapter 5 Research Chapter 6 Program Planning Chapter 7 Communication Chapter 8 Evaluation Part 3 Strategy Chapter 9 Public Opinion and Persuasion Chapter 10 Conflict Management: Dealing with Issues, Risks, and Crises Chapter 11 Reaching Diverse Audiences Chapter 12 Public Relations and the Law Part 4 Tactics Chapter 13 The Internet and Social Media Chapter 14 Preparing Materials for Mass Media Chapter 15 Radio and Television Chapter 16 Meetings and Events Part 5 Application Chapter 17 Corporations Chapter 18 Entertainment, Sports, and Tourism Chapter 19 Politics and Government Chapter 20 Global Public Relations Chapter 21 Nonprofit, Health, and Education
[Acute rheumatic fever: 27 year experience from the Montreal's pediatric tertiary care centers].

OBJECTIVES To examine the epidemiology, clinical characteristics and outcomes in a cohort of children with acute rheumatic fever (RF) over the past 27 years in Montreal. METHODS The medical records of patients younger than 18 years of age hospitalized and diagnosed with RF in Montreal between January 1979 and December 2005 were reviewed. RESULTS Among the initial 134 charts selected, 36 children were already followed-up for chronic RF and the remaining 98 patients (51 % females) who fulfilled the Jones criteria for acute RF were included in the analysis. The mean age at diagnosis was 10.1 +/- 3.0 years (range: 3-17). Over the 27-year study period, there was a mean incidence of 3.6 patients/year without peaks, but onset occurred in the last 15 years in almost two-thirds of the patients. Forty-nine percent of the patients were Canadian-born non-aboriginal (CbnA) and the remaining patients were Canadian-born aboriginal (CbA) or foreign-born (Fb). Carditis was diagnosed in 73 % of the patients and Sydenham's chorea in 49 %. Of the CbnA children, 39 % had carditis compared with 61 % of children from other ethnic groups (P = 0.003). However, the form of presentation was chorea in 69 % of CbnA children vs. 31 % of children from other ethnic groups (P < 0.001). No deaths were attributable to acute RF although 2 % of the patients relapsed during the study period. Severe cardiac sequelae requiring valve replacements occurred in 6.1 %. CONCLUSION The incidence of acute RF in Montreal was low but consistent over the 27-year study period. Clinical presentation varied depending on ethnicity.
Transperineal Sonography of Anal Mass Status Post Total Colectomy: A Case Report

Transperineal sonography is a diagnostic tool for imaging the pelvic floor and lower pelvis. Because of the higher spatial resolution of pelvic sonography compared with other cross-sectional imaging techniques, transperineal sonography can provide detailed visualization of the lower pelvic organs, including the urethra, vagina, and anorectum. This case report describes the use of transperineal sonography for evaluation of an indeterminate lower pelvic process seen on computed tomography in a 53-year-old woman with progressive pelvic pain, dysuria, and dyspareunia. Because of severe dyspareunia, the patient declined transvaginal sonography. Transperineal sonography provided diagnostic imaging of the anal mass causing these symptoms.
Effects of Sensor Size, Surface Material, and Contact Area on Pressure Measurements in Thin-Film Pressure Sensors

The existing studies on foot pressure measurement have primarily focused on sensor placement and the number of sensors instead of sensor size and the ground above the sensor; moreover, there is limited research available on the use of different materials in pressure measurement devices manufactured by various companies. This study, therefore, aimed to address these gaps by investigating the measurement accuracy in standard loading conditions, considering different sensor sizes, contact areas, and ground surfaces. Pressure was applied within the sensing diameter of the sensor, and a microcontroller was used to calculate the reciprocal resistance. The results of the study indicated that the coating of sensors with different materials and the shape of the contact surface of the object applying pressure significantly influenced the measurements of the pressure sensors. When comparing the difference according to the sensor sizes, medium-size sensor (18.3 mm); according to surfaces, thin–thick plastazote; according to loading conditions, oval contact areas gave more sensitive values. Future research can further build upon these findings to enhance the design and development of pressure measurement devices, ultimately benefiting scientific research and clinical applications.
Calibration of a Wide-Angel Digital Camera System for Near Real Time Scenarios

Near real time monitoring of natural disasters, mass events, and large traffic disasters with airborne SAR and optical sensors will be the focus of several projects in research and development at the German Aerospace Center (DLR) in the next years. For these projects, new airborne camera systems are applied and tested. An important part of the sensor suite plays the recently developed optical wide angle 3K camera system (3K = “3Kopf”), which consists of three non-metric off-the-shelf cameras (Canon EOS 1Ds Mark II, 16 MPixel). The cameras are aligned in an array with one camera looking in nadir direction and two in oblique sideward direction, which leads to an increased FOV of max 110°/ 31° in across track/flight direction. With this camera configuration, a high resolution, colour and wide-area monitoring task even at low flight altitudes, e.g. below the clouds, becomes feasible. The camera system is coupled to a GPS/IMU navigation system, which enables the direct georeferencing of the 3K optical images. The ability to acquire image sequences with up to 3Hz broadens the spectrum of possible applications in particular for traffic monitoring. In this paper, we present the concept of calibration and georeferencing which is adjusted to the requirements of a near real time monitoring task. The concept is based on straight forward georeferencing, using the GPS/IMU data to automatically estimate the not-measured boresight angles. To achieve this without measuring of ground control points (GCPs), we estimate on-the-fly boresight angles based on automatically matched 3-ray tie points in combination with GPS/IMU measurements. A prerequisite for obtaining robust results for the boresight angles is that the air plane attitude changes slightly during image taking; through these singular solutions can be avoided. Additionally, we assume known and fixed parameters of interior orientation. The determination of the interior orientation is performed ground based using a bundle adjustment of images from a calibration test field. The determination of the parameters of the interior orientation is repeated to check for their systematic changes in time. The proposed georeferencing and calibration concept was tested with images acquired during three flight campaigns in 2006. To evaluate the accuracy obtained by direct georeferencing using the proposed estimation procedure for the boresight angles without GCPs, the data are compared with the results of a bundle adjustment using GCPs and the GPS/IMU information. Summarizing, the RMSE of direct georeferencing with/without GCPs is 1.0m / 5.1m in position and 0.5m / 1.0m in height, at image scales of 1:20.000. The accuracy without GCPs is regarded as acceptable for near real time applications. Additionally, it is shown that the parameter of the interior orientation remain stable during three repetitive calibrations on a test field for all three cameras.
Seasonal Variations in Antibiotic Resistance Gene Transport in the Almendares River, Havana, Cuba

Numerous studies have quantified antibiotic resistance genes (ARG) in rivers and streams around the world, and significant relationships have been shown that relate different pollutant outputs and increased local ARG levels. However, most studies have not considered ambient flow conditions, which can vary dramatically especially in tropical countries. Here, ARG were quantified in water column and sediment samples during the dry- and wet-seasons to assess how seasonal and other factors influence ARG transport down the Almendares River (Havana, Cuba). Eight locations were sampled and stream flow estimated during both seasons; qPCR was used to quantify four tetracycline, two erythromycin, and three beta-lactam resistance genes. ARG concentrations were higher in wet-season versus dry-season samples, which combined with higher flows, indicated much greater ARG transport downstream during the wet-season. However, water column ARG levels were more spatially variable in the dry-season than the wet-season, with the proximity of waste outfalls strongly influencing local ARG levels. Results confirm that dry-season sampling provides a useful picture of the impact of individual waste inputs on local stream ARG levels, whereas the majority of ARGs in this tropical river were transported downstream during the wet-season, possibly due to re-entrainment of ARG from sediments.