Miracle-dz/UniFAR-FTUs huggingface dataset:
First report of an invasive pest, Phyllonorycter populifoliella (Lepidoptera: Gracillariidae) from Ladakh

Phyllonorycter populifoliella (Treitschke 1883), is an invasive pest and is first reported on poplar trees, from the eastern region of Ladakh, India. The details of the taxonomic identification based on genital morphology are presented. Besides, host range, feeding habits and level of infestation in different hamlets of Ladakh are also presented. This study is important for further understanding the pest biology, its diversity and management by adopting control strategies. It is also important to restrict its dispersal to other states of the Indian union and to devise pest management strategies for this pest.
An Online Cost Calculator for Estimating the Economic Cost of Illness Due to Shiga Toxin-Producing E. coli (STEC) 0157 Infections

Shiga toxin-producing E. coli (STEC) O157 is a significant cause of foodborne illness in the United States. ERS estimated the economic cost of illness due to this pathogen— $405.2 million (in 2003 dollars)—using the most recent estimate (1997) of the annual number of STEC O157 cases by the Centers for Disease Control and Prevention (CDC) and medical and cost data from the Foodborne Diseases Active Surveillance Network. CDC is currently updating its estimate of annual cases. As new information becomes available, the ERS online Foodborne Illness Cost Calculator enables users to review and modify the assumptions underlying the STEC O157 cost estimate, such as the number of cases, and then recalculate the cost, adjusted for inflation for any year from 1997 to 2006. The potential utility of the calculator was demonstrated by assuming that the incidence of STEC O157 had declined and then estimating the cost for a smaller number of cases.
α2-macroglobulin-rich serum as a master inhibitor of inflammatory factors attenuates cartilage degeneration in a mini pig model of osteoarthritis induced by “idealized” anterior cruciate ligament reconstruction

Post-traumatic osteoarthritis is a special type of osteoarthritis and a common disease, with few effective treatments available. α2-Macroglobulin (α2M) is important to chondral protection in post-traumatic osteoarthritis. However, its injection into xenogeneic joint cavities involves safety hazards, limiting clinical applications. Exploring serum α2M-enriching strategies and the therapeutic effect and mechanism of α2M-rich serum (α2MRS) autologous joint injection to treat post-traumatic osteoarthritis has significant value. In the present study, a unique filtration process was used to obtain α2MRS from human and mini pig serum. We evaluated the potential of α2MRS in protecting against post-surgery cartilage degeneration. We identify the potential of α2MRS in reducing the expression of inflammatory cytokines and factors that hasten cartilage degeneration in post-operative conditions leading to post-traumatic osteoarthritis. The potential of α2MRS was analyzed in interleukin-1β induced human chondrocytes and mini pig models. In the chondrocyte model, α2MRS significantly promoted human chondrocyte proliferation and reduced apoptosis and chondrocyte catabolic cytokine gene transcription and secretion. The anterior cruciate ligament autograft reconstruction model of mini pigs was randomized into groups, operated on, and injected with α2MRS or saline. The results showed that α2MRS injection significantly suppressed the levels of inflammatory factors, improved gait, and showed significantly lower cartilage degeneration than the groups that did not receive α2MRS injections. This study highlights the chondroprotective effects of α2MRS, elucidated its potential applications against cartilage degeneration, and could provide a basis for the clinical translation of α2MRS.
A manufacturing network design model based on processor and worker capabilities

This paper presents an optimization methodology to design networks of manufacturing facilities producing several products under deterministic demand. The bill of materials and the operations for each product are taken into account through the use of a product-state graph. Starting from the current state of the manufacturing network, the approach considers a multi-period planning horizon. For each period it specifies the facilities to open within the set of current and potential facilities, the mission for each of the centres in the selected facilities, the equipment to be used for producing the goods, and the structure of the network. Taking human resource competencies into account, the approach selects the type of workers to use for executing the manufacturing tasks. The transfer of resources between plants is also considered. A multi-period mixed integer linear programming model is formulated, a solution method based on the addition of specialized cuts is proposed and computational results are presented.
Werkstoffliche Untersuchungen an explantierten Hüftpfannen aus ultrahochmolekularem Polyethylen (UHMW PE) Material Analysis of Retrieved UHMW Polyethylene Hip Cups

[5] Henßge, J., H. Grundei, R. Edspüler: Anatomisch richtiges Design von Femurschaftimplantaten. Z. Orthop. 118 (1980), 592 [6] Hanslik, L. , J. Henßge: Wissenschaftliche Ausstellung: »Spongiöses Implantat«. Nordwestdeutscher Orthopädenkongreß, Krefeld 1982 [7] Henßge, J., L. Hanslik: Wissenschaftliche Ausstellung: »Zementfreie Implantate mit spongiösem Überzug«. Kongreß der DGOT Essen 1983 [8] Judet, R. : Totale Hüftendoprothesen aus Porometall ohne Zementverankerung. Z. Orthop. 113 (1975), 828 [9] Mittelmeier, H. : Selbsthaftende Keramik-Metallverbundprothese. MOT 96 (1976), 104-105 [10] Mittelmeier, H. : Zementlose Verankerung von Endoprothesen nach dem Tragrippenprinzip. Z. Orthop. 112 (1974), 27-33 [11] Thomas, W. , H. Grundei: Die anatomische GT-Gleitachsenendoprothese des Kniegelenkes. Z. Orthop. 120 (1982), 22-28 [12] Willert, H. -G. , P. Puls: Die Reaktion des Knochens auf Knochenzement bei der Alloarthroplastik der Hüfte. Arch. Orthop. Unfallchir. 72 (1972), 33
The Potential of Electronic Communication and Information Technologies as Research Tools: Promise and Perils for the Future of Communication Research

Scholars across several disciplines praise the methodological advantages afforded to research endeavors by the use of electronic communication and information technologies. At the same time, however, scholars note several disadvantages stemming from the use of these tools. To assess the utility of electronic communication and information technologies as research tools, we synthesize work on the methodological issues surrounding the use of these technologies for the future of communication research. Our overarching goal is to review prior and current perspectives in order to appropriately assess and critique the use of electronic tools in research pursuits while informing future applications of these tools in the field. Throughout the chapter we articulate the argument that sound theoretical and methodological practices determine the appropriateness of the application of any particular tool. Accordingly, our focus is on the specific methodological concerns that arise with the use of electronic technologies in the conduct of research. We organize our discussion into six major sections: sampling issues; data integrity concerns, including the reliability and validity of research design and measures; the potential afforded by electronic communication and information technologies; contemporary ethical considerations; an explicit assessment of the future of communication research in view of the application of electronic technologies; and a concluding section that establishes the contribution of our review and briefly outlines outstanding issues.
Penggunaan Berbagai Bahan Pengikat Terhadap Kualitas Fisik Dan Kimia Pelet Hijauan Makanan Ternak (Effect Of Binder On Physical And Chemical Quality Of Grass Pellet)

Penelitian ini dilakukan untuk mengkaji pengaruh berbagai bahan pengikat terhadap kualitas fisik (durabilitas dan densitas) serta kimia (kandungan protein kasar dan energi) pelet hijauan makanan ternak. Rancangan percobaan menggunakan Rancangan Acak Lengkap (RAL). Perlakuan terdiri atas 3 dosis jagung (20, 30, 40 %) dari tepung hijauan, molasses (20, 30, 40 %), gaplek (20,30, 40 %) dan tapioka (20,30, 40 %), masing-masing perlakuan dengan tiga kali ulangan. Hasil penelitian memperlihatkan bahwa dilihat dari sifat fisiknya, molasses merupakan bahan pengikat untuk pelet hijauan yang paling baik yaitu dengan campuran 40 % dari tepung hijauan memberikan durabilitas 89,5 % dan densitas sebanyak 370,2 kg per m3, kemudian gaplek (40 %) memberikan durabilitas 85,2 %, densitas 326,7 % dan jagung (40 %) yang memberikan durabilitas 85,0 % dan densitas 269,0 kg per m3. Bahan pengikat dari gaplek (20 dan 30 %), tapioka (20 dan 30 %), dan jagung (30 dan 40 %), menghasilkan kandungan protein kasar pelet hijauan yang tidak berbeda nyata yaitu masing-masing 13,4 %, 12,5 %, 13,4 %, 11,8 %, 12,0 % dan 12,7 %. Kandungan energi tertinggi diperoleh dari campuran bahan pengikat tapioka 30 dan 40 % yaitu sebesar 4222 dan 4374 kkal/kg, kemudian jagung (20,30,40 %) yaitu 3580,3597 dan 3790 kkal/kg. Ka t a kunci : Bahan pengikat, durabilitas, densitas, kandungan kimia, pelet hijauan
Auditory neuron models for cochlea implants

Auditory perception neurons, also called inner hair cells (IHCs), because of their physical shape, transform the mechanical movements of the basilar membrane into electrical impulses. The impulse coding of the IHC is the main information carrier in the auditory process and is the basis for improvements of cochlea implants as well as for low rate, high quality speech processing and compression. This paper compares biologically motivated models (MEDDIS, COOKE, BRACHMAN-PAYTON) with a newly developed model which is transfer function oriented. The new model has only three reservoirs and the parameters can be controlled through five small ROM tables. We compare this model with the often used MEDDIS model in terms of accuracy, system parameter flexibility, and hardware effort in an FPGA implementation.
The Challenges and Opportunities in the Development of MicroRNA Therapeutics: A Multidisciplinary Viewpoint

microRNAs (miRs) are emerging as attractive therapeutic targets because of their small size, specific targetability, and critical role in disease pathogenesis. However, <20 miR targeting molecules have entered clinical trials, and none progressed to phase III. The difficulties in miR target identification, the moderate efficacy of miR inhibitors, cell type-specific delivery, and adverse outcomes have impeded the development of miR therapeutics. These hurdles are rooted in the functional complexity of miR’s role in disease and sequence complementarity-dependent/-independent effects in nontarget tissues. The advances in understanding miR’s role in disease, the development of efficient miR inhibitors, and innovative delivery approaches have helped resolve some of these hurdles. In this review, we provide a multidisciplinary viewpoint on the challenges and opportunities in the development of miR therapeutics.
An Analysis on Synchronous Reluctance Motors by Use of Magnetic Circuit.

The synchronous reluctance motors operated by a PWM inverter can be designed for the maximum saliency ratio (Ld/Lq). The saliency ratio is the most important parameter for achieving a high torque capability, high power factor and wide constant-power speed range. Generally, flux guides for the d-axis and flux barriers for the q-axis are provided to achieve a high Ld and low Lq, respectively, in order to maximize the saliency ratio. In this paper, the optimal shape and thickness of the flux barriers are investigated analytically. It is also demonstrated that the optimal rotor flux barrier shape can be expressed as the contour line of the function that shows the magnetic potential in a uniform material rotor. The effects of the magnetic resistance of the stator and the gap are also analyzed.
Exploring the Relationship between Design Approach and Play Value of Outdoor Play Spaces

Abstract This paper reports research that explores the relationship between approaches to the ‘design’ of outdoor play spaces and the play value of these spaces. The paper starts by explaining that there is an assumption that an outdoor space in the Kit, Fence, Carpet (KFC) style provides fewer opportunities for play than spaces designed in a more natural way. To test this hypothesis an evaluation tool is developed that draws upon a range of academic literature. The tool includes three dimensions of Play Value, Physical Characteristics of the site and the Environmental Characteristics of the site. This tool was tested on 10 sites in the East Midlands in England. The results indicate that there is a continuum between KFC and more natural spaces with a mid-category of ‘composite’ spaces. Play value increases along this continuum between the two styles while characteristics such as the amount and type of fixed play equipment and the use of loose and moving parts also vary between the types.
Design of Single Neuron Adaptive PID Based on Quadratic Performance Index for Linear DC Motor

In this paper, a new control strategy is put forward, which is a single neuron PID control based on the quadratic performance index (QPI) learning algorithm. This single neuron PID control is self-learning and self-adjusting. Through the study of system performance, the weights of the neuron are adjusted by the QPI learning algorithm. The new strategy solves the contradiction between fast tracking performance and robustness in the positioning servo system. In addition, the mathematic model of voice coil motor is analyzed. In order to improve the fast response performance and disturbance suppression of the position loop, the Two-Degree-of-Freedom (TDOF) control is proposed. The simulation results show that disturbance rejection and dynamic performance of the VCM servo control system have been improved. Compared with the utilizing traditional PID system, this new control strategy has stronger self-adapting and robustness.
Microengineered 3D in vitro model of human pulmonary alveoli: Curvature's influence on lung epithelial cells

Tissue engineering aims to create functional tissues and in vitro biological structures using different technologies, approaches and to address different goals. An important strategy to have a better understanding of human organs and their interactions is by developing in vitro models that represent their anatomy and physiology. In the particular case of this thesis, in order to mimic the human alveoli on a 3D in vitro model, efforts have to be made to develop a structure which shape and dimension are as close as possible to the native one in the human body (around 100μm in depth and 200μm in diameter [1][2][3]). Human lung in vitro models have been developed and improved for the past years, upgrading from two dimensional (2 D) models to three dimensional (3 D) conformation, such as lung organoids[4], but none in literature displays curvature in their platforms, which is believed to affect cells’ behaviour. Thus, the aim of this work was to investigate the influence of curvature on human lung epithelial cells on curved platforms created by thermoforming and modified via ion track etching. There are several technologies that enable fabrication of curved structures but gas-assisted microthermoforming allows the creation and replication of really thin walled microcavities, preserving any pre-modification of the used polymer such as irradiation with energetic heavy particles. Polycarbonate was the chosen material mainly because of its biocompatibility, mechanical and thermal characteristics. Different parameters were tested to optimise gas-assisted microthermoforming and ion track etching in order to achieve a structure that was as close as possible to the human alveoli’ dimensions and shape. To assess the impact of substrate’s curvature on epithelial cells, proliferation, apoptosis, cell density, cell-substrate adhesion, cell-cell interaction and metabolic activity assays were performed. Samples were analysed and characterised by specific immunostainings by respective fluorescent imaging, by scanning electron microscope (SEM) and by laser scanning microscope
Multiclass Bid-Rent Network Equilibrium Model

A two-way interaction between transport and land use is generally acknowledged, but conventional approaches in travel demand analyses and urban economics have not satisfactorily represented this mutual relationship. The bid-rent network equilibrium model adopted a bilevel program under game theory for addressing this reciprocal interaction. However, the transport component of the model assumed only one type of household. This structure resulted in difficulties in representing class-specific behavior and interclass interactions of transport. This problem can be mitigated by incorporating a multiclass framework, which establishes a multiclass bid-rent network equilibrium model. The single- and multiclass models are tested on an artificial network. The simulation intends to demonstrate the ability of the model to represent the relationship between transport and the location of activities. The result shows that the developed model successfully addresses the two-way interaction and a Nash equilibrium intended.
A monolithic fully-integrated vacuum-sealed CMOS pressure sensor

This paper presents an integrated multitransducer capacitive barometric pressure sensor that is vacuum-sealed at wafer level. The interface circuitry is integrated directly within the sealed reference cavity, making the device immune to parasitic environmental effects. The overall device process merges BiCMOS circuitry with a dissolved wafer transducer process, is compatible with bulk- and surface-micromachining, and employs chemical mechanical polishing (CMP), anodic bonding, and hermetic lead transfers. The sensor achieves 15b resolution and is suitable for low-cost packaging. The device is composed of a programmable switched capacitor readout circuit, five segmented-range pressure transducers, and a reference capacitor, all integrated on a 7.5/spl times/6.5 mm/sup 2/ die using 3 /spl mu/m features.
The Emotional Sensibility Estimation System for Front-load Washer

The door-lock switch is one of the most important part in the front-load washer. As an safety system, it keeps the door locked while the front-load washer or the dish washer is working and generating heat and spin. The door of front-load washer needs the emotionality as well as the safety because the consumers always get feels when using it. In this paper, We study about emotional factors in the door of front-load washer and analyze the difference of emotionality as the structure of the door-lock switch changed. For this, we analyze the force graph by using the software and the jig which can measure the force while the door is opened or closed.
Current conveyor-based voltage-mode two-phase and four-phase quadrature oscillators

A voltage mode two-phase quadrature oscillator using plus-type second generation current conveyors [CCIIs(+)] is realized by using a simple technique. The basic building block for this technique is a voltage mode non-inverting band-pass filter. The two-phase quadrature oscillator is then transformed into a four-phase quadrature oscillator by replacing the two CCIIs(+) by two dual output, current conveyors [DO-CCIIs]. The proposed circuits enjoy attractive features such as use of grounded passive components, independent frequency control, outputs of almost equal magnitude and low sensitivity figures. Both the oscillator circuits are designed and verified using PSPICE simulation.
Guidance for emergency medicine pharmacists to improve care for people with opioid use disorder

The Emergency Medicine Pharmacist (EMP) is uniquely trained to play a vital role in the management of patients who use opioids and patients with opioid use disorder (OUD). The emergency department (ED) is at the forefront of the opioid epidemic, as it serves as a primary place of treatment for patients experiencing opioid overdose, opioid withdrawal, and other complications related to opioid use. Given the size of the epidemic and the limited availability of treatment facilities and providers, the ED provides an opportunity to meet the needs of this patient population. Emergency Medicine Pharmacists can take an active role in the expansion of access to treatment of OUD, overdose education and prevention, and harm‐reduction interventions. Emergency Medicine Pharmacists have the ability to identify patients who would benefit from therapy, initiate appropriate treatment, provide patient counseling and education, lead the development of institution‐specific protocols and clinical decision tools, and assist in the evaluation of current strategies at their institution. Emergency Medicine Pharmacists' knowledge and understanding of the pharmacology of the drugs used to treat OUD is unique and should be utilized to improve patient care for this population. Further, EMPs are poised to limit the emergence of OUD before it begins through the implementation of opioid stewardship activities both within the ED and upon discharge. This article seeks to review the ways in which EMPs can support efforts in the ED to improve the care of people with OUD.
Comparative thermal analysis of different rotor types for a high-speed permanent-magnet electrical machine

A thermal analysis of three different rotor constructions for a high-speed permanent-magnet electrical machine is performed. The first type of rotor has a carbon-fibre sleeve for retaining the magnets against the centrifugal forces and an aluminium shield for eddy currents. The other two rotors have retaining sleeves made of different titanium alloys and do not have additional eddy-current shields. The thermal analysis of the rotor types is performed using two completely different approaches. The first implemented method is a numerical-multiphysics one that couples computational fluid dynamics equations with heat-transfer equations. For better reliability of the analysis, a traditional thermal-network method is also implemented for estimation of the temperature distribution in the examined rotors. The accuracy of the aforementioned methods is verified using experimental results for the average temperature rise of the permanent magnets. The results obtained from the implemented methods show that although the rotor with a retaining sleeve made of titanium alloy Ti-6%Al-6%V-2%Sn does not have any eddy-current shield, it fulfils the thermal constraints and can be implemented for high-speed applications.
Mobile Phones as Traffic Probes: Practices, Prospects and Issues

Abstract The provision of road‐based travel‐time information often relies on speed data collected from inductive loops imbedded in the pavement. While inductive loops are commonly installed on urban freeways, they are neither configured nor ideally located to provide speed data on arterial roads. Dissemination of dynamic, network‐wide travel information to road users is, therefore, likely to require alternative data collection techniques. This review considers the state of practice in relation to using mobile phones as traffic probes, assesses the prospects for this data collection option and identifies unresolved issues that may have implications for obtaining real‐time traffic information using mobile phones as probes. The use of mobile phones as traffic probes is appealing because the necessary infrastructure is already in place in most urban areas. Traffic speed information can be obtained by passively monitoring data transmission in the mobile phone network. International experience provides encouraging signs about the potential of mobile phones as traffic probes. Issues still to be resolved include potential public concerns about privacy, growing awareness of the road safety implications of mobile phone use and the need to understand better the quality of the data obtained from mobile phone probes.