Miracle-dz/UniFAR-FTUs huggingface dataset:
A Robust Fuzzy Fractional Order PID Design Based On Multi-Objective Optimization For Rehabilitation Device Control

In this context, Fuzzy Fractional Order Proportional Integral Derivative (FOPID-FLC) controllers are emerged as efficient approaches due to their flexibility and ability to handle nonlinearities and uncertainties. This paper proposes the use of a FOPID-FLC controller for a two-degree-of-freedom (2-DOF) lower limb exoskeleton. Our proposal is based on an enhanced control approach that combines fuzzy logic advantages and fractional calculus benefits. Contrary to popular existing methods, that use the FLC to tune the FOPID parameters, the FLC in this work is used to generate the system torque depending on patient morphology. Indeed, our fundamental contribution is to design and implement an enhanced FOPID-FLC that achieves an adequate optimal control based on system rules composed of optimal torques and input data. The fractional calculus is approximated using successive first order filters. Next, a multi-objective optimization is established for the tuning of each FOPID parameters. Finally, the FLC is used to adjust the torque depending on the kid's age. The effectiveness of the proposed controller in various scenarios is validated based on numerical simulations. Extensive analyses prove that the FOPID-FLC outperforms the FOPID with a 90\% of improvement in terms of error performance indices and 20\% of improvement for the control action. Moreover, the controller exhibits improved robustness against uncertainties and disturbances encountered in rehabilitation environments.
Advancing Quality Assurance In Manufacturing: A Weighted Exponential Distribution Control Chart For Enhanced Production Monitoring

Over the last few decades, weighted distributions have received substantial attention from researchers due to their utility across a range of research fields. With an emphasis on the relevance of weighted distributions, a new control chart for a weighted exponentially distributed characteristic using an exponentially weighted moving average (EWMA) has been proposed in this manuscript. The average run length of both in-control and out-of-control processes has been derived. The efficiency of the proposed control chart has been compared with existing chart based on the unweighted exponential distribution in terms of Average Run Length (ARL) and the percentage decrease in ARL (ΔARL) using Monte Carlo Simulations. Furthermore, the proposed control chart has been applied to various real-life applications to highlight its applicability in industrial and manufacturing processes.
Performance Analysis of Routing Protocols (AODV, DSR, GRP) in Indoor and Outdoor Surroundings

The main focus of this paper is to do comparative analysis for mobile ad-hoc protocols based on the area of the coverage with indoor and outdoor surrounding communications. We have taken three routing protocols AODV, DSR, GRP to evaluate the performance by using OPNET simulator. We have evaluated the parameters like delay, throughput and network load to see the performance. It is interesting to see the communication coverage variation in indoor scenarios where obstacles are comparatively high as compared to outdoor surroundings.
Research on the Impact of Open Innovation on the Business Performance of Aerospace Equipment Manufacturing Enterprises

Amidst the accelerating pace of the digital economy, industries across the spectrum are increasingly embracing open innovation to enhance competitive edge of their products. Open innovation fosters the connection of internal and external resources and facilitates resource integration. However, the central issue that scholars are now focusing on is whether the adoption of open innovation genuinely brings significant changes in corporate performance and what the pathways of influence are. This paper is based on extensive literature review and domestic and data collection. engages in a theoretical analysis of the impact of open innovation actions in aerospace equipment manufacturing companies on operational performance. It puts forth corresponding hypotheses. Subsequently, through meticulous analysis and organization, this study selects 108 publicly listed companies on the Shanghai and Shenzhen stock markets that meet the criteria, covering the years from 2007 to 2022 as the subjects of investigation. It employs the virtual variable “Open Innovation” as an explanatory variable and complements it with one mediating variable and four control variables for empirical research. The following conclusions are drawn: Presently, the adoption of open innovation effectively enhances corporate performance. Open innovation influences corporate operational performance by impacting the company's internal integration capability. This paper presents practical and feasible recommendations from both a national and corporate perspective, facilitating their thriving development in the future.
Effect of Selective Z-Pinning on the Static and Fatigue Strength of Step Joints between Composite Adherends

The z-pinning reinforcement technique, which involves inserting thin pins through the body of a laminate, has proven highly effective in enhancing the strength of various composite joint configurations. This investigation aims to explore the enhancements achievable through selective z-pinning at very low pin contents on both the static and fatigue performance of composite joints. Single-step joints between carbon/epoxy adherends were reinforced using steel pins arranged in two, three, or four rows of pins parallel to the edges of the overlap, resulting in pin contents ranging from 0.2% to 0.4%. Joint panels were manufactured through co-curing, and coupons were extracted from the panels for static and fatigue tensile testing. The experimental tests show that z-pinning improves the static strength (by about 15%) and extends the fatigue lives of the joints. The ultimate failure of both unpinned and pinned joints is due to the unstable propagation of a crack at the bond line. The superior performances of pinned joints are mainly due to the bridging tractions imposed between the crack faces by z-pins, which delay the growth of the debonding crack. The enhancements in static and fatigue strength achieved by z-pinning were essentially independent of the number of pin rows, and the pins positioned near the joint edges were found to play a dominant role in controlling the structural performance of pinned joints.
INDIKATOR ENTOMOLOGI DALAM PENGENDALIAN VEKTOR TERPADU (PVT) MENUJU ELIMINASI MALARIA DI KABUPATEN NUNUKAN, KALIMANTAN UTARA

ABSTRACT Nunukan Regency is one of the malaria endemic areas in North Kalimantan Province. This study aims to identify the entomology indicators in integrated vector management in Nunukan District to further be considered in achieving malaria elimination in the region. The study was carried out on Sebatik Island, Nunukan Regency, North Kalimantan Province. Data analysis was carried out descriptively. The results showed that the value of vectorial capacity (VC) calculation for An. peditaeniatus (0.008) and An. sundaicus (0.057). Entomological inoculation rate (EIR) An. peditaeniatus and An. sundaicus is 0.08 (~ 28 infective bites / person / year). It can be concluded that vectorial capacity and entomological inoculation rate can be used as an indicator of entomology of malaria transmission and malaria transmission patterns in Sungai Nyamuk Village. Intensification of vector control in an integrated manner is needed in order to accelerate malaria elimination in Nunukan District. Integrated Vector Managemen (IVM) on Sebatik Island involves cross-sectoral participation, namely from the Health Office, the Public Works Agency, the Agriculture and Livestock Services Office, the Plantation Service Office, and the active community participation approach. Keywords: Malaria, Anopheles sp, integrated vector manajemen ABSTRAK Kabupaten Nunukan merupakan satu di antara daerah endemis malaria di Provinsi Kalimantan Utara. Penelitian ini bertujuan untuk mengidentifikasi indikator entomologi dalam pengendalian vektor terpadu di Kabupaten Nunukan, selanjutnya menjadi bahan pertimbangan dalam tercapainya eliminasi malaria di wilayah tersebut. Penelitian dilaksanakan di Pulau Sebatik, Kabupaten Nunukan-Kalimantan Utara. Analisis data dilakukan secara deskriptif. Hasil penelitian menunjukkan bahwa nilai penghitungan vectorial capacity (VC) untuk An. peditaeniatus (0,008) dan An. sundaicus (0,057). Nilai entomological inoculation rate (EIR) An. peditaeniatus dan An. sundaicus adalah 0.08 (~28 gigitan infektif /orang/tahun). Dapat disimpulkan bahwa vectorial capacity dan entomological inoculation rate dapat digunakan sebagai indikator entomologi penularan malaria dan pola penularan malaria di Desa Sungai Nyamuk. Intensifikasi pengendalian vektor secara terpadu sangat diperlukan dalam rangka akselerasi eliminasi malaria di Kabupaten Nunukan. Pengendalian Vektor Terpadu (PVT) di Pulau Sebatik melibatkan peran serta lintas sektor yaitu dari Dinas Kesehatan, Dinas Pekerjaan Umum, Dinas Pertanian dan Peternakan, Dinas Perkebunan serta pendekatan partisipasi aktif masyarakat. Kata kunci: Malaria, Anopheles sp, V.C. , E.I. R. , pengendalian vektor terpadu
The Azores - Westernmost Europe: where evolution can be caught red-handed

Very often we see the "wheels of Progress" as treacherous hopes that, under the golden promises of improving the standard of life, roll over life itself and leave behind them a path of destruction and impoverishment. Apparently, there is no return in the process, for every time a correction is made it catches the river farther downstream, where the scenario is different, the challenges are different, the ways of thinking are different and, consequently, the hopes, dreams and values may not be the same. It is a dynamic process, one that has at its heart the pulsating force of the future. Yet a similar environment surrounds Evolution. In the name of life itself, Evolution personifies the continuous change, the ever-present adaptation, the merciless struggle for life. The consequences, however, set both realities apart. The "wheels of Progress", alias, the "wings of Progress" proceed at a rate to which Nature is not accustomed, hence the impoverishment resulting thereafter. Time is what Evolution needs; time is what Progress cuts short. For that reason, if in the prosecution of the latter we disrespect the former, although we may.succeed in a short term, in the long run we will be the main losers, for time is on Nature's side and we will not be playing by Nature's rules.
Oral Potentially Malignant Disorders and Oral Cancer in Saudi Arabia: An Epidemiological Review of the Literature

Background: Oral potentially malignant disorders (OPMDs) are a group of chronic oral mucosal diseases associated with an increased risk of malignant transformation. Multiple studies have investigated the prevalence of these conditions in multiple regions; however, there are limited data about the prevalence of OPMDs in the Kingdom of Saudi Arabia (KSA). This paper aims to review the prevalence of OPMDs in the KSA, to ensure better understanding of the population risk and propose a more standardised approach to the diagnosis and management of this group across the KSA. In addition, this review will discuss the prevalence of oral cancer in the KSA, considering independent risk factors for oral cancer development. Methods: Electronic databases including PubMed, Medline, Medscape, ScienceDirect, StatPearls, BMC Oral Health and the Cochrane Library were searched with the keywords “Oral Potentially Malignant Disorders”; “Saudi Arabia”; and “Oral Cancer”. Identified articles were reviewed independently by 2 reviewers against defined inclusion and exclusion criteria. Results: 16 studies were included in this review. The prevalence of OPMDs in KSA varies significantly depending on age, gender, social habits, background disease and dental status. Conclusions: This review highlights the need for up-to-date data on the prevalence, distribution, and characteristics of OPMDs in KSA. The diverse prevalence rates and distinct characteristics of various OPMDs emphasise the necessity for targeted preventive measures. As the data on OPMDs in KSA remains limited, future research efforts should prioritise the establishment of comprehensive epidemiological studies to inform effective public health interventions in this region.
Analisis Artificial Hip Joint Saat Melakukan Gerakan Salat Menggunakan FEM

Saat ini sendi panggul atau biasa disebut dengan hip joint merupakan sendi yang sangat penting dalam sistem kerangka manusia. Sendi panggung sering mengalami kerusakan yang disebabkan oleh banyak faktor. Kerusakan pada sendi panggul biasanya menyyebabkan pasien harus menggunakan sendi panggul buatan atau biasa disebut dengan artificial hip joint. Penggantian sendi panggul buatan mencapai 600.000 pasien pada tahun 2005. Penduduk di Indoensia yang mayoritas beragama muslin membuat pengguna artificial hip joint menggunakannya untuk melakukan gerakan salat, sedangkan artificial hip joint yang dibuat oleh Eropa tidak diperuntukan untuk melakukan gerakan salat. Pada penelitian kali ini disimpulkan bahwa sendi panggul buatan atau artificial hip joint buatan Eropa tidak cocok untuk melakukan gerakan salat yaitu gerakan tahiyat awal dan tahiyat akhir karena terjadi dislokasi dan impigment pada artificial hip joint.
Enhanced Reduction of Ferredoxin in PGR5-Deficient Mutant of Arabidopsis thaliana Stimulated Ferredoxin-Dependent Cyclic Electron Flow around Photosystem I

The molecular entity responsible for catalyzing ferredoxin (Fd)-dependent cyclic electron flow around photosystem I (Fd-CEF) remains unidentified. To reveal the in vivo molecular mechanism of Fd-CEF, evaluating ferredoxin reduction–oxidation kinetics proves to be a reliable indicator of Fd-CEF activity. Recent research has demonstrated that the expression of Fd-CEF activity is contingent upon the oxidation of plastoquinone. Moreover, chloroplast NAD(P)H dehydrogenase does not catalyze Fd-CEF in Arabidopsis thaliana. In this study, we analyzed the impact of reduced Fd on Fd-CEF activity by comparing wild-type and pgr5-deficient mutants (pgr5hope1). PGR5 has been proposed as the mediator of Fd-CEF, and pgr5hope1 exhibited a comparable CO2 assimilation rate and the same reduction–oxidation level of PQ as the wild type. However, P700 oxidation was suppressed with highly reduced Fd in pgr5hope1, unlike in the wild type. As anticipated, the Fd-CEF activity was enhanced in pgr5hope1 compared to the wild type, and its activity further increased with the oxidation of PQ due to the elevated CO2 assimilation rate. This in vivo research clearly demonstrates that the expression of Fd-CEF activity requires not only reduced Fd but also oxidized PQ. Importantly, PGR5 was found to not catalyze Fd-CEF, challenging previous assumptions about its role in this process.
Shape Estimation under General Reflectance and Transparency

In recent years there has been significant progress in increasing the scope, accuracy and flexibility of 3D photography methods. However there are still significant open problems where complex optical properties of mirroring or transparent objects cause many assumptions of traditional algorithms to break down. In this work we present three approaches that attempt to deal with some of these challenges using a few camera views and simple illumination. First, we consider the problem of reconstructing the 3D position and surface normal of points on a time-varying refractive surface. We show that two viewpoints are sufficient to solve this problem in the general case, even if the refractive index is unknown. We introduce a novel “stereo matching” criterion called refractive disparity, appropriate for refractive scenes, and develop an optimization-based algorithm for individually reconstructing the position and normal of each point projecting to a pixel in the input views. Second, we present a new method for reconstructing the exterior surface of a complex transparent scene with inhomogeneous interior. We capture images from each viewpoint while moving a proximal light source to a 2D or 3D set of positions giving a 2D (or 3D) dataset per pixel, called the scatter-trace . The key is that while light transport within a transparent scene's interior can be exceedingly complex, a pixel's scatter trace has a highly-constrained geometry that reveals the direct surface reflection, and leads to a simple “Scatter-trace stereo” algorithm for computing the exterior surface geometry. Finally, we develop a reconstruction system for scenes with reflectance properties ranging from diffuse to specular. We capture images of the scene as it is illuminated by a planar, spatially non-uniform light source. Then we show that if the source is translated to a parallel position away from the scene, a particular scene point integrates a magnified region of light from the plane. We observe this magnification at each pixel and show how it relates to the source-relative depth of the surface. Next we show how calibration relating the camera and source planes allows for robustness to specular objects and recovery of 3D surface points.
Nitrogen Plasma Treatment of Composite Materials Based on Polylactic Acid and Hydroxyapatite

The effect of surface modification by an arc discharge plasma in a nitrogen flow with treatment durations of 5 and 10 min on the physicochemical properties and biocompatibility of the surface of composites based on polylactic acid and hydroxyapatite (PLA/HA) with different mass ratios (80/20, 70/30, 60/40) has been investigated. The aim of this work was to show the correlation between the changes of the physicochemical characteristics (chemical compound, morphology, wettability) of the surface layer of the PLA/HA composites and the cell viability (macrophages) in the presence of the plasma-modified materials. The dependence of alterations of the functional properties (wettability, biocompatibility) on the change in the chemical composition under the plasma exposure has been established. The chemical composition was studied using X-ray photoelectron spectroscopy (XPS), the surface morphology was researched with scanning electron microscopy (SEM), and the wettability of the composite’s surface was analyzed by measuring the contact angle and surface energy calculation. In addition, the viability of macrophages was investigated when the macrophages from three donors interacted with a modified PLA/HA surface. It was found that the formation of the new functional groups, –C-N and N-C=O/C=O, improves the wettability of the surface of the composites and promotes the viability of macrophages in the presence of the composite materials. The fundamental principles for obtaining promising materials with the required properties for eliminating bone defects have been created.
Mechanisms of mesothelial cell response to viral infections: HDAC1-3 inhibition blocks poly(I:C)-induced type I interferon response and modulates the mesenchymal/inflammatory phenotype

Infectious peritonitis is a leading cause of peritoneal functional impairment and a primary factor for therapy discontinuation in peritoneal dialysis (PD) patients. Although bacterial infections are a common cause of peritonitis episodes, emerging evidence suggests a role for viral pathogens. Toll-like receptors (TLRs) specifically recognize conserved pathogen-associated molecular patterns (PAMPs) from bacteria, viruses, and fungi, thereby orchestrating the ensuing inflammatory/immune responses. Among TLRs, TLR3 recognizes viral dsRNA and triggers antiviral response cascades upon activation. Epigenetic regulation, mediated by histone deacetylase (HDAC), has been demonstrated to control several cellular functions in response to various extracellular stimuli. Employing epigenetic target modulators, such as epidrugs, is a current therapeutic option in several cancers and holds promise in treating viral diseases. This study aims to elucidate the impact of TLR3 stimulation on the plasticity of human mesothelial cells (MCs) in PD patients and to investigate the effects of HDAC1-3 inhibition. Treatment of MCs from PD patients with the TLR3 agonist polyinosinic:polycytidylic acid (Poly(I:C)), led to the acquisition of a bona fide mesothelial-to-mesenchymal transition (MMT) characterized by the upregulation of mesenchymal genes and loss of epithelial-like features. Moreover, Poly(I:C) modulated the expression of several inflammatory cytokines and chemokines. A quantitative proteomic analysis of MCs treated with MS-275, an HDAC1-3 inhibitor, unveiled altered expression of several proteins, including inflammatory cytokines/chemokines and interferon-stimulated genes (ISGs). Treatment with MS-275 facilitated MMT reversal and inhibited the interferon signature, which was associated with reduced STAT1 phosphorylation. However, the modulation of inflammatory cytokine/chemokine production was not univocal, as IL-6 and CXCL8 were augmented while TNF-α and CXCL10 were decreased. Collectively, our findings underline the significance of viral infections in acquiring a mesenchymal-like phenotype by MCs and the potential consequences of virus-associated peritonitis episodes for PD patients. The observed promotion of MMT reversal and interferon response inhibition by an HDAC1-3 inhibitor, albeit without a general impact on inflammatory cytokine production, has translational implications deserving further analysis.
Comparative Metabolomics of Ligulate and Tubular Flowers of Two Cultivars of Calendula officinalis L.

Calendula officinalis L. is a well-known plant widely used in traditional medicine due to the presence of various biologically active compounds. The main raw material for the production of medicinal preparations is the inflorescence, which consists of ligulate and tubular flowers. However, the characteristics of the metabolome of these flowers are not fully understood. This study identified and compared the levels of major metabolites in the ligulate and tubular flowers of two C. officinalis cultivars, ‘Golden Sea’ (GS) and ‘Paradise Garden’ (PG). The metabolome was analysed using ultra-performance liquid chromatography with photodiode array detection and a Q Exactive Orbitrap high-resolution mass spectrometer. It was found that the tubular flowers of both PG and GS cultivars had higher levels of lipids, phenolamides and caffeoylquinic acids and lower levels of triterpenoid glycosides than the ligulate flowers. It was also shown that the inflorescences of the GS, which had a 35% higher proportion of tubular flowers, contained 30% more phenolic compounds and 50% more lipids than the PG. Thus, the results obtained extend our understanding of the features in the metabolomes of ligulate and tubular flowers and suggest that the quality of inflorescences of C. officinalis cultivars, as a source of medicinal preparations, is strongly influenced by the proportion of ligulate and tubular flowers.