Miracle-dz/UniFAR-FTUs huggingface dataset:
2 The sine-Gordon chain 2 . 1 Generalities

A nonlinear system possessing a natural forbidden band gap can transmit energy of a signal with a frequency in the gap, as recently shown for the nonlinear chain of coupled pendula [Phys Rev Lett 89 (2002) 134102]. This process of nonlinear supratransmission, occurring at a threshold exactly predictable in many cases, is shown to have a simple experimental realization with a mechanical chain of pendula coupled by a coil spring. It is then analyzed in more detail by first going to different (non-integrable) systems which do sustain nonlinear supratransmission. Then a Josephson transmission line (one dimensional array of short Josephson junctions coupled through super-conducting wires), is shown to sustain also nonlinear supratransmission, though being related to a different class of boundary conditions, and despite the presence of damping, finiteness and discreteness. Finally the mechanism at the origin of nonlinear supratransmission is a nonlinear instability, and it is briefly discussed here.
Lawrence Berkeley Laboratory. Materials & Molecular Research ON A STATIONARY PLANAR ELECTRODE

Multi-sweep cyclic voltammetry applied to electrodeposition at a stationary planar electrode under conditions of semi-infinite linear diffusion is analyzed in terms of current and charge density functions. A hypothetical periodic state obtained at an infinite reversal overpotential serves as a lower bound for the values of the current function, which has as an upper bound the current measured on -the first sweep. Another hypo thetical periodic state reached by continuous cycling depends on the chosen finite value of the reversal o.verpotential. -A quasi-periodic state is defined when current functions do not change significantly with further cycling. -2-zero current~ the current at the start of the second cathodic sweep is anodic; the value of this anodic current depends both on sweep rate and the reversal overpotential. Relative to linear sweep multi~ sweep cyclic voltammetry generates characteristic currents that are unique to each sweep~ thereby multiplying the criteria for reversibility manyfold. However~ cyclic voltammetry also creates a substantial net deposit on each sweep~ and any resulting surface area change with repeat ed cycling would make the multi-sweep diagnostics meaningless.
Analysis of supporting indicators for innovation in Romania compared to neighboring EU countries

The paper presents a comparative study of indicators which targeting the facilities and support for the innovation process. The study targets indicators regarding human resources, support structure / infrastructure and legislative provisions. The analysis is carried out over the last 5 years, comparing the indicators in Romania and the neighboring countries (Bulgaria, Hungary, Austria, Slovakia and Poland) and highly developed countries (Germany and France). Based on this study, will be drawing conclusions for improvement of these indicators. The indicators that will be taken into consideration are: Availability of scientists and engineers, Researchers, Quality of the education system, Researchers in Research and Development, Research and development expenditure, Firm-level technology absorption, University-industry collaboration in Research & Development, Quality of scientific research institutions, Gross domestic spending on Research and Development, Property rights, Intellectual property protection.
Steady state infiltration rate studies of lower Loko soils, Adamawa state, north east Nigeria

The study was conducted at Lower Loko west of song local Government, Adamawa state. Infiltration, bulk density, and some physicochemical analysis were carried out on the five sites, designated as site 1A and B, site 2A and B, site 3A and B, site 4A and B and site 5A and B, based on the preliminary survey to characterize the steady state infiltration rate. The study confirmed infiltration variability in the area both within the sites and across the sites. The soils are characterized by low to moderately rapid steady state infiltration rate range from 4.98 cmhr -1 to 11.61 cmhr -1 for all the five sites with the cumulative infiltration range from 1.00 cmhr -1 to 6.58 cmhr -1 on the average for all the five sites in 3hours of infiltration. Variability was influenced by differences in the texture, bulk density and water holding capacity. Moreover, improved infiltration, reduced erosion menace in low steady state infiltration sites. Flooding in the lake, use of integrated nutrient management on the fields and construction of drainages in the area is suggested.
Isoliquiritigenin, an orally available natural FLT3 inhibitor from licorice, exhibits selective anti-AML efficacy in vitro and in vivo

Licorice is a medicinal herb widely used to treat inflammation-related diseases in China. Isoliquiritigenin (ISL) is an important constituent of Licorice and possesses multiple bioactivities. In this study, we examined the selective anti-AML (Acute myeloid leukemia) property of ISL via targeting FLT3, a certified valid target for treating AML. In vitro , ISL potently inhibited FLT3 kinase with an IC 50 value of 115.1 ± 4.2 nM, selectively inhibited the proliferation of FLT3-ITD or FLT3-ITD/F691L mutant AML cells. Moreover, it showed very weak activity towards other tested cell lines or kinases. Western blot immunoassay revealed that ISL significantly inhibited the activation of FLT3/Erk1/2/STAT5 signal in AML cells. Meanwhile, Molecular docking study indicated that ISL could stably form aromatic interactions and hydrogen bonds within the kinase domain of FLT3. In vivo , oral administration of ISL significantly inhibited the MV4-11 flank tumor growth and prolonged the survival in the bone marrow transplant model via decreasing the expression of Ki67, and inducing apoptosis. Taken together, the present study identified a novel function of ISL as a selective FLT3 inhibitor. ISL could also be a potential natural bioactive compound for treating AML with FLT3-ITD or FLT3-ITD/F691L mutations. Thus, ISL and licorice might possess potential therapeutic effects for treating AML, providing a new strategy for anti-AML.
02 11 10 1 v 1 1 8 N ov 2 00 2 Decoherence control in microwave cavities

We present a scheme able to protect the quantum states of a cavity mode against the decohering effects of photon loss. The scheme preserves quantum states with a definite parity, and improves previous proposals for decoherence control in cavities. It is implemented by sending single atoms, one by one, through the cavity. The atomic state gets first correlated to the photon number parity. The wrong parity results in an atom in the upper state. The atom in this state is then used to inject a photon in the mode via adiabatic transfer, correcting the field parity. By solving numerically the exact master equation of the system, we show that the protection of simple quantum states could be experimentally demonstrated using presently available experimental apparatus.
FIToplankton: Wireless Controlled Remotely-operated Underwater Vehicle (ROV) for Shallow Water Exploratio

Remotely Operated Vehicle (ROV) for underwater exploration is typically controlled using umbilical cable connected to ground control station. Unfortunately, while it’s used for power distribution and data transmission, it also obstruct the movement of ROV especially for shallow water (<50 cm). This paper proposed an alternative method for controlling ROV using wireless remote control system. This work also aims to explore the possibility of using RF wireless technology between 420-450 MHz as underwater communication system. Furthermore, the control system was used to manage actuators i.e. DC motor and bilge pump for maneuvring and picking small size cargo. To help the ROV to hold on a desired, Inertial Measurement Unit (IMU) is installed on board ROV within maximum deviation 0.2 m/s2. The prototype of the system has been successfully implemented and evaluated to confirm the functionality and the feasibility of the proposed approach.
Comparative Transcriptome Analysis Reveals Common and Speciﬁc Tags for Root Hair and Crack-Entry Invasion in Sesbania rostrata 1[W][OA]

The legume Sesbania rostrata provides its microsymbiont Azorhizobium caulinodans with versatile invasion strategies to allow nodule formation in temporarily ﬂooded habitats. In aerated soils, the bacteria enter via the root hair curling mechanism. Submergence prevents this epidermal invasion by accumulation of inhibiting concentrations of ethylene and, under these conditions, the bacterial colonization occurs via intercellular cortical infection at lateral root bases. The transcriptome of both invasion ways was compared by cDNA-ampliﬁed fragment length polymorphism analysis. Clusters of gene tags were identiﬁed that were speciﬁc for either epidermal or cortical invasion or were shared by both. The data provide insight into mechanisms that control infection and illustrate that entry via the epidermis adds a layer of complexity to rhizobial invasion.
Improvement in sperm quality by oral antioxidant supplementation in infertile men with varicocele who have not undergone surgical repair: Systematic review and meta‐analysis

The aim of this systematic review and meta‐analysis was to assess whether oral antioxidant supplementation improves sperm quality in men with infertility and varicocele (VCL) who have not undergone surgical repair. In men with infertility and VCL who had not undergone surgical repair oral antioxidant supplementation significantly increased sperm concentration (WMD +5.86 × 106/ml 95% CI: +1.47 to +10.24, p < 0.01; random effects model, six studies, 213 patients), total motility (WMD + 3.76%, 95% CI: +0.18 to +7.34, p = 0.04; random effects model, three studies, 93 patients), progressive motility (WMD + 6.38%, 95% CI: +3.04 to +9.71, p < 0.01; random effects model, three studies, 84 patients) and seminal volume (WMD +0.55 ml, 95%CI: +0.06 to +1.04, p = 0.03; random effects model, four studies, 120 patients). On the other hand, no significance difference was observed in sperm morphology (WMD +3.89%, 95% CI: −0.14 to +7.92, p = 0.06; random effects model, five studies, 187 patients). In conclusion, limited evidence suggests that the use of oral antioxidants in men with infertility and VCL, who have not undergone surgical repair improves their seminal volume, sperm concentration, total and progressive motility.
A Study on the Impact of Voluntary Disclosure Level on Value Relevance of Accounting Information of Firms Listed in Tehran Stock Exchange (TSE)

This paper seeks to explore whether voluntary disclosure level affects the value relevance of accounting information, specifically, earnings and book values of Firms Listed in Tehran Stock Exchange (TSE). Based on the assumption that an increased focus on the informational needs of investors should increase the value relevance of the information contained in financial statements, we expect that greater voluntary disclosure levels among companies listed on the TSE will be associated with greater value relevance in earnings and book value information for investors. Statistical sample includes 71 companies during 2011 to 2016. Statistical technique used to test the hypotheses is the Multivariate Regression. The results of the price model provide evidence that earnings and book values are significant factors in the valuation of firms Listed in TSE. Other results show that the voluntary disclosure level increase leads to the increase of information content of the earnings and book values.
Relating Vehicle-Wildlife Crash Rates to Roadway Improvements

Animal-Vehicle Crashes are a growing trend in America, and Wyoming in particular. The focus of this research effort is to determine the effect of road reconstruction on the number of animal-vehicle crashes using changes in the reported animal-vehicle crash rates. Using GIS tools, the entire Wyoming highway system was analyzed using 10 years of reported crash data to determine both the frequency and crash rate of animal-vehicle crashes on each roadway segment. Seven reconstruction projects were selected for the study. Statistical analyses were performed with a focus on crash rates. The seven sections were analyzed as an aggregate data set, and it was determined that wild animal-vehicle crash rates experienced increases following reconstruction. During this same period, those crash rates not associated with animal-vehicle crashes, as well as the overall crash rate, were generally observed to decrease. An analysis of changes in roadway design attributes was performed, and the only attribute observed to have a statistically significant impact on the animal-vehicle crash rate was design speed.
Mutant allele-specific uncoupling of PEN3 functions reveals engagement of the ABC 24 transporter in distinct tryptophan metabolic pathways

: Arabidopsis PENETRATION ( PEN ) genes quantitatively contribute to the execution of 60 different forms of plant immunity upon challenge with diverse leaf pathogens. PEN3 encodes 61 a plasma membrane-resident pleiotropic drug resistance-type ATP-binding cassette 62 transporter and is thought to act in a pathogen-inducible and PEN2 myrosinase-dependent 63 metabolic pathway in extracellular defense. This metabolic pathway directs the intracellular 64 biosynthesis and activation of tryptophan (Trp)-derived indole glucosinolates for subsequent 65 PEN3-mediated efflux across the plasma membrane at pathogen contact sites. However, 66 PEN3 functions also in abiotic stress responses to cadmium and indole-3-butyric acid (IBA)- 67 mediated auxin homeostasis in roots, raising the possibility that PEN3 exports multiple 68 functionally unrelated substrates. Here we describe the isolation of a pen3 allele, designated 69 pen3-5 , which encodes a dysfunctional protein that accumulates in planta like wild-type 70 PEN3. The specific mutation in pen3-5 uncouples PEN3 functions in IBA-stimulated root 71 growth modulation, flg22-induced callose deposition and pathogen-inducible salicylic acid 72 accumulation from PEN3 activity in extracellular defense, indicating the engagement of 73 multiple PEN3 substrates in different PEN3-dependent biological processes. We identified 4- 74 O -β- D -glucosyl-indol-3-yl formamide (4OGlcI3F) as a pathogen-inducible Trp-derived 75 compound that over-accumulates in pen3 leaf tissue and whose biosynthesis is dependent on 76 an intact PEN2 metabolic pathway. We propose that a precursor(s) of 4OGlcI3F is the PEN3 77 substrate in extracellular pathogen defense. These precursors, the shared indole core present 78 in IBA and 4OGlcI3F, and allele-specific uncoupling of a subset of PEN3 functions, suggest 79 that PEN3 transports distinct indole-type metabolites in distinct biological processes. we demonstrate an allele-specific uncoupling of a subset of PEN3 functions. We then applied metabolic profiling of pathogen-inoculated wild type and pen3 plants to identify pathogen-inducible compounds that hyperaccumulate in pen3 leaf tissue. Purification and mass spectrometry of a prominent hyperaccumulating compound identified an indole derivative, 4OGlcI3F, whose biosynthesis is dependent on the PEN2 metabolic pathway. We propose that one or several precursors of this molecule serve as the PEN3 substrate(s) for export into the apoplast during extracellular defense. regulon conserved in monocot and dicot plants defines a functional module in antifungal plant immunity. An Arabidopsis Callose Synthase, GSL5, Is Required for and
`Comparison of Conventional Maximum Power Point Tracking Algorithm with Artificial Neural Network Based Maximum Power Point Tracking Algorithm with Respect to Change in Load

In recent times the main source of energy is fossil fuels which is deposited beneath the earth surface years ago. Due to increased population, the deposited fossil fuels have been severely exploited emitting huge amount of toxins in the environment that diminish the quality of human life. This gave birth to explore the renewable energy. The most abundant source of renewable energy available to us is the Solar Energy, but due to inability of the PV cells to track maximum power point due to varying weather conditions and changing load it is necessary to intensify the output power of the Solar Photovoltaic. In this paper artificial neural network based maximum power point tracking algorithm is proposed to enhance the power output of the Solar PV with changing load and comparison between Perturb and Algorithm, Incremental Conductance and Artificial Neural Network has been done to determine the performance. The purpose of the study is to prove the effectiveness of artificial neural network with varying load over the time.
Non Linear Companding Transform for Peak to Average Power Ratio Reduction in Ofdm System

— High Peak-to-average-power-ratio (PAPR) is a problem associated with OFDM systems. Various companding schemes are used to reduce the problem of PAPR in orthogonal frequency division multiplexing schemes. High PAPR drives the power amplifiers used at the transmitter’s side into non-linear region and leads to high power dissipation in hand held devices. Signal companding is one of the widely used techniques to reduce high PAPR.
Non-invasive assessment of exercise-related intramyocellular acetylcarnitine in eu- and hyperglycemia in patients with type 1 diabetes using 1 H-magnetic resonance spectroscopy: A randomized single-blinded cross-over study

a Department of Clinical Research, MR Spectroscopy and Methodology, University of Bern, Switzerland b Division of Endocrinology, Diabetes and Clinical Nutrition; Inselspital, University Hospital and University of Bern, Switzerland c International Centre for Circulatory Health, National Heart and Lung Institute, Imperial College at St. Mary’s, London, United Kingdom d Institute for Diagnostic, Interventional and Pediatric Radiology, Inselspital, University Hospital and University of Bern, Switzerland e Metabolic Unit, Children's University Hospital and University of Bern, Switzerland
Demographic, Clinical and Management Characteristics of Newly Diagnosed COPD Patients in Turkey: A Real-Life Study

Purpose: In order to determine the clinical and sociodemographic characteristics of newly diagnosed treatment-naïve asthma and COPD patients in Turkey, a multicenter study in 2012 was initiated . We aimed to investigate the characteristics and therapies of COPD patients in the original study in more detail. Patients and Methods: This nation-wide, multicentric, non-interventional, prospective, real-life observational cohort study was conducted in 122 centers. The newly diagnosed patients were not receiving any treatment before the recruitment. Their general characteristics, the combined GOLD 2011 COPD categories and exacerbation histories were noted. The patients were fol-lowed up with 3 voluntary visits for 1 year. Their adherence to the inhaled treatment according to GOLD 2011 was evaluated during follow-up visits. Results: The study included 776 COPD patients. Their mean age was 59.4±9.1 years, and 11.9% of the patientswere female. 35.1% of the patients were in the GOLD 2011 C and Dcategory. 12.6% are frequent exacerbators, and 52.8% had at least one comorbid condition. 71.8% overtreatment rate was detected. Their attendance rates for three follow-up visits became 55.9%, 32.9% and 18.7%, respectively. The adherence rate to the treatment was measured as 81.9%. Conclusion: Although these patients were diagnosed for the ﬁ rst time, the GOLD C and D categories and frequent exacerbator phenotype were found at a high rate. They were usually prescribed an overtreatment regimen. We think that newly diagnosed COPD patients should be evaluated carefully, and best effort should be made to treat these patients in accordance with the recommendations of the major COPD guidelines.
The Retromer Complex Protein VPS35 Modulates Iron Homeostasis by Regulating Hepcidin-Induced Ferroportin Degradation

The Retromer Complex protein VPS35 Modulates Iron Homeostasis Regulating Abstract Hepcidin-mediated degradation of the iron exporter Ferroportin is an essential mechanism for iron homeostasis. Upon Hepcidin binding to the Ferroportin receptor at the cell surface, Ferroportin is rapidly internalized and degraded. However, the underlying mechanism for the degradation has not been uncovered. Using a functional genomics approach, VPS35, a member of the Retromer Complex, is identified as an important regulator for Hepcidin-induced Ferroportin degradation. Cells with CRISPR-induced mutation in VPS35 demonstrated significantly reduced Ferroportin degradation in the presence of Hepcidin. Interestingly, VPS35 mutations and dysfunction of other members of the Retromer Complex have been associated with familial autosomal-dominant Parkinson’s disease, a progressive neurodegenerative disease with well-established iron accumulation phenotype. The result of this study reveals a previously unappreciated role for the Retromer Complex in the regulation of iron homeostasis. to identify specific for the Hepcidin-induced thus the screen Hepcidin-treated to Analysis of the results revealed VPS35 as a potent regulator of Hepcidin-mediated Ferroportin degradation. VPS35, a core member of the Retromer Complex, a screen hit specifically regulating FPN1-GFP level in the presence of Hepcidin. Validation results demonstrate that of VPS35 Hepcidin-induced Ferroportin The Retromer This study provides novel insights into Ferroportin degradation and suggests a potential role of the Retromer Complex in Ferroportin turnover and Hepcidin-mediated iron homeostasis.
Compact self-powered synchronous energy extraction circuit design with enhanced performance

Synchronous switching circuit is viewed as an effective solution of enhancing the generator’s performance and providing better adaptability for load variations. A critical issue for these synchronous switching circuits is the self-powered realization. In contrast with other methods, the electronic breaker possesses the advantage of simplicity and reliability. However, beside the energy consumption of the electronic breakers, the parasitic capacitance decreases the available piezoelectric voltage. In this technical note, a new compact design of the self-powered switching circuit using electronic breaker is proposed. The envelope diodes are excluded and only a single envelope capacitor is used. The parasitic capacitance is reduced to half with boosted performance while the components are reduced with cost saved.
Classical Self-dual variables and Loop Quantum Gravity ∗ Last updated by ,

This bibliography attempts to give a comprehensive overview of all the literature related to what is known as the AshtekarSen connection and the Rovelli-Smolin loop variables, from which the program currently known as Loop Quantum Gravity emerged. The original version was compiled by Peter Hübner in 1989, and it has been subsequently updated by Gabriela González, Bernd Brügmann, Monica Pierri, Troy Schilling, Christopher Beetle, Alejandro Corichi and Alberto Hauser. The criteria for inclusion in this list are the following: A paper in the classical theory is included if it deals with connection variables for gravity. If the paper is in the quantum domain, it is included when it is related directly with gravity using connection/loop variables, with mathematical aspects of connections, or when it introduces techniques that might be useful for the construction of the (loop) quantum theory of gravity. Information about additional literature, new preprints, and especially corrections are always welcome. Previous title: Bibliography of Publications related to Classical and Quantum Gravity in terms of Connection and Loop Variables. Even older title: Bibliography of publications related to classical and quantum gravity in terms of the Ashtekar variables. corichi@nucleares.unam. mx