Miracle-dz/UniFAR-FTUs huggingface dataset:
Case Report Unusual Presentations of Intestinal Schistosomiasis

Schistosomiasis is a common parasitic infestation that affects 200 million people worldwide. There are more than 76 endemic countries that suffer from this infestation, leading to 200,000 deaths annually. Intestinal schistosomiasis is known to cause a variety of serious gastrointestinal complications. Thus, it is important to diagnose it early to prevent such complications and relieve symptoms early. A typical infection with intestinal schistosomiasis tends to present with chronic diarrhea, abdominal pain, dysentery, and in severe cases portal hypertension and hepatosplenomegaly. However, in this study the authors report two cases that came with unusual presentations of intestinal schistosomiasis during their outpatient clinic evaluation. Case Presentation: The first patient is a 33-year-old male Yemeni national who was referred for investigation of a pedunculated rectal polyp. The patient was otherwise asymptomatic with no significant medical history. The second patient is a 39-year-old male Saudi national who presented with constipation, abdominal pain, and bloating. The patient was initially diagnosed as a case of irritable bowel syndrome and was managed conservatively for 2 years with no improvement. Conclusion: Histopathological evidence via biopsies revealed intestinal schistosomiasis in both patients. Therefore, in endemic areas it remains important to keep intestinal schistosomiasis in the differentials when dealing with vague intestinal signs and symptoms. It is also important to not rule out schistosomiasis from a negative stool egg screening alone as this tool tends to yield false negative results during acute infections and low-intensity chronic infections.
Polysemy in Design Review Conversations

This paper examines the role of polysemy, defined as the quality of having multiple meanings, in design review conversations. It examines the polysemy, particularly of nouns, involved in a dataset of design review conversations with reference to design ideas. The purpose is to determine whether polysemy is related to successful development of design ideas and more creative design outcomes. The results show that the polysemy of nouns involved in the conversations of the finally developed, successful, design ideas exceeds in the most cases the average polysemy involved in the conversations pertaining to the unsuccessful design ideas. Furthermore, the polysemy of these nouns is linked to high overall creativity of the design idea. The paper concludes by discussing issues and directions for further investigation of polysemy.
The arithmeticity of certain torus bundle cone 3-manifolds and hyperbolic surface bundle 3-manifolds; and an enhanced arithmeticity test

The manifold M obtained by 0-surgery on the figure eight knot is a torus bundle over S1, and the core Σ of the surgery is a section of the bundle. The pair (M,Σ) admits a structure as a hyperbolic cone-manifold with cone angle α∈(0,2π). For α of the form 2π/n with n>1, it is a hyperbolic orbifold (M,n). Using an arithmeticity test from one of their previous papers, the authors prove that (M,n) is arithmetic if and only if n=2,3. The test has been enhanced by eliminating an unnecessary condition. Taking branched coverings of the (M,n) yields an explicit construction of many hyperbolic surface bundles over S1, both arithmetic and non-arithmetic.
Is your request just this? New automation paradigm to reduce the requests of transition without increasing the effort of the driver

: The scope of this paper is to describe an innovative interaction paradigm between the driver and highly automated vehicles, developed in AutoMate EU project. This new interaction modality is based on the cooperation, i.e. the mutual support in perception and in action between the driver and the car. The cooperation aims to exploit and make concrete the complementarity of the human and the automation as part of a team. The concept has been tested by evaluating the system that more than others allows the driver to cooperate with the vehicle, i.e. the HMI. The results of the exploratory study show that the cooperation is well perceived, understood and accepted by the users. In particular, the Human to Automation support in perception, the most innovative concept proposed by the project, has shown the potential to reduce the effort requested to the driver to understand how to support the automation as well as the effort to actually support it to cooperatively deal with situations the automation cannot cope with.
Catharsis: Journal of Arts Education Social Action in Tongkling Performing ART

_________________________________________________________________ Tongkling is a traditional music from Glodogan village, Bawen District, Semarang Regency. Tongkling is always invited to take part in Merti Dusun and Kirab Budaya events in Semarang regency. The purpose of this research is to analyze the form of performance and social action in Tongkling art. The method used in this research was qualitative with sociological approach. The technique of data collection were observation, interview, and document study. The technique of data validity used triangulation technique and data analysis technique that follow interactive model analysis stages. The research results show that the form of Tongkling art presentation are divided into traditional and electric types. The traditional types is presented during carnival while electric types is presented on the stage. The social action of the society is also developing, the beginning was for patrolling, and nowadays, this art is for enliven Kirab Budaya and Merti Dusun evenst in Semarang Regency. The research implication of Tongkling Ortega for the society in Glodogan village is for social interaction and for preserving the existence of Tongkling in traditional events. Tongkling Ortega art increases the art treasury in Semarang Regency.
Genome-wide identification of PbrbHLH family genes, and 1 expression analysis in response to drought and cold stresses in 2 pear

30 Background: The basic helix-loop-helix (bHLH) transcription factors play important 31 roles in many processes in plant growth, metabolism and responses to abiotic stresses. 32 Although, the sequence of Chinese white pear genome (cv. ‘Dangshansuli’) has 33 already been reported, there is still a lack of clarity regarding the bHLH family genes 34 and their evolutionary history. 35 Results: In this work, a genome-wide identification of the bHLH genes in Chinese 36 white pear was performed, and we characterized the functional roles of these 37 PbrbHLH genes in response to abiotic stresses. Based on the phylogenetic analysis 38 and structural characteristics, 197 identified bHLH genes could be well classified into 39 21 groups. Expansion of PbrbHLH gene family were mainly driven by WGD and 40 dispersed duplication with the purifying selection from the recent WGD. The 41 functional annotation enrichment showed that the majority of PbrbHLHs were 42 enriched in the GO terms and KEGG pathways involved in responds to stress 43 conditions as TFs. Transcriptomic profiles and qRT-PCR revealed that PbrbHLH7 , 44 PbrbHLH8 , PbrbHLH116 , PbrbHLH128 , PbrbHLH160 and PbrbHLH195 were 45 significantly up-regulated under cold and drought treatments. In addition, 46 PbrbHLH195 -silenced pear seedlings display significant reduced cold tolerance, 47 exhibiting reduced chlorophyll content, as well as increased Electrolyte leakage and 48 concentrations of malondialdehyde and H 2 O 2 . 49 Conclusion : For the first time, a comprehensive analysis identified the bHLH genes 50 in Chinese white pear and demonstrated that PbrbHLH195 is involved in the 51 production of ROS in response to cold stress, suggesting that members of the 52 PbrbHLH family play an essential role in the stress tolerance of pear. 53 transcription factor gene TabHLH1 is crucial in mediating osmotic stresses tolerance through modulating largely the ABA-associated pathway.
Identiﬁcation of a Gene Negatively Affecting Antibiotic Production and Morphological Differentiation in Streptomyces coelicolor A3(2) (cid:1)

SC7A1 is a cosmid with an insert of chromosomal DNA from Streptomyces coelicolor A3(2). Its insertion into the chromosome of S. coelicolor strains caused a duplication of a segment of ca. 40 kb and delayed actinorhodin antibiotic production and sporulation, implying that SC7A1 carried a gene negatively affecting these processes. The subcloning of SC7A1 insert DNA resulted in the identiﬁcation of the open reading frame SCO5582 as nsdA , a gene negatively affecting Streptomyces differentiation. The disruption of chromosomal nsdA caused the overproduction of spores and of three of four known S. coelicolor antibiotics of quite different chemical types. In at least one case (that of actinorhodin), this was correlated with premature expression of a pathway-speciﬁc regulatory gene ( actII-orf4 ), implying that nsdA in the wild-type strain indirectly repressed the expression of the actinorhodin biosynthesis cluster. nsdA expression was up-regulated upon aerial mycelium initiation and was strongest in the aerial mycelium. NsdA has DUF921, a Streptomyces protein domain of unknown function and a conserved SXR site. A site-directed mutation (S458A) in this site in NsdA abolished its function. Blast searching showed that NsdA homologues are present in some Streptomyces genomes. Outside of streptomycetes, NsdA-like proteins have been found in several actinomycetes. The disruption of the nsdA -like gene SCO4114 had no obvious phenotypic effects on S. coelicolor . The nsdA orthologue SAV2652 in S. avermitilis could complement the S. coelicolor nsdA -null mutant phenotype. , where the desired mutation is underlined) and W40231 (5 (cid:6) -GCGTTCGGCGCGGACCTTCTTG G-3 (cid:6) ), were designed complementary to opposite strands of the S458-encoding region of nsdA and containing the desired mutation. The mutagenesis PCR was carried out with Pfu DNA polymerase. Dimethyl sulfoxide was added to the reaction mixture to a ﬁnal concentration of 5% (vol/vol). After temperature cycling, the PCR product was treated with DpnI to digest the methylated paren-tal DNA template and to select for mutation-containing synthesized DNA. The mixture was then used to transform E. coli DH5 (cid:2) . Plasmid DNA from two transformants was sequenced to show that the inserted DNA fragments con- tained the designed mutation and there was no other mutation. Then the 1.3-kb SacI fragment was excised from the mutated plasmid pHZ2733* and used to replace the same fragment in pHZ2731 to generate pHZ2735. The 2-kb region from 479 bp upstream to 40 bp downstream of nsdA in pHZ2735 was sequenced to conﬁrm the designed TCCGCC mutation and that there was no other mutation.
Postnatal depression: predictors and prophylaxis

The purpose of the study was to evaluate the effectiveness of prevention of post-stroke depression in patients with acute cerebrovascular accident It was shown that the incidence of PID in patients with ischemic stroke exceeds 30%. In assessing the role of various risk factors among the examined patients with PID, the prevalence of male patients (OR = 1.3 (1.1-1.5)), under the age of 55 (1.7 (1.3-1.9 )), with indications in the history of episodes of depression in the past (1.6 (1.4-1.8)), as well as alcohol abuse (1.2 (1.0-1.3)). In 31 (58.5%) there was a localization of focal ischemia in the frontal lobe of the dominant hemisphere. The use of both SIRS and an antidepressant with multimodal effect - vortioxetine was sufficiently effective in PID, but vortioxetin showing the best results - from 8,8  0,1 points to 6,2  0,1 points. The paper considers the expediency of the use of vorothoxetine in order to prevent PID in patients with ischemic stroke.
Fluorescence detection of biological objects with ultraviolet and visible light-emitting diodes

Department of Analytical and Environmental Chemistry, Vilnius University, Naugarduko 24, LT-03225 Vilnius, LithuaniaRecent progress in fabrication of semiconductor light emitting diodes (LEDs) allows thesedevices to be used for excitation of fluorescence of aromatic amino acids and other biofluorophores.In our work, a deep-UV UVTOP
T he T axaTion of i nTernaTionally P orTable P ensions : a n i nTroducTion To f iscal i ssues and P olicy o PTions

The development in old-age pensions in OECD countries exhibits several characteristic features. First, oldage income3 consists of a mix of public, occupational, and private retirement incomes whose components have become more diversified and variable. Second, countries encourage occupational and private retirement savings through tax preferences or direct subsidies to compensate for reduced public generosity. Third, the taxation of mandatory and voluntary pension savings deviates from the principles of comprehensive income taxation within and between countries. Finally, individuals spend more of their working life or retirement period abroad, facilitated by the improved portability of benefits between OECD countries, but also within key migration corridors.
WORKING PAPER SERIES ON RESEARCH IN RELATIONSHIP MANAGEMENT On Modeling Resource-Strategy-Performance Linkages

We develop a parsimonious model to analyze the dynamic adjustment between resource, strategy, and performance (R-S-P). We also provide insights gained from analyzing prototypical contexts. The roots of the R-S-P model are predominantly in resource-based theory, the empirical findings of dynamic strategic groups literature, reference point theory, and learning theory. Our results show the emergence of complex behaviors of strategy changes, industry structure and performance variations from simple rules. We explain performance variations over time not as outcomes of random processes or irrational acts on the part of managers, but as emerging from industry dynamics based on strategy adjustments to achieve improved performance. Our modeling efforts form the base for more textured empirical and more general computational research to be carried out in the future.
THE KIDNEY ROLE IN REGULATION OF CIRCADE RITHMS OF THE ORGANISM

Review of the literature concerns the organization of circadian rhythms and the place of kidney in their regulation. The description of the central pacemaker (the suprachiasmatic nucleus of the hypothalamus) and its interaction with the peripheral oscillators, including – the kidney is discussed. The daily fluctuations of excretory kidney function, the velocity of glomerular filtration and tubular reabsorption are viewed. The modern views on the provision of circadian rhythms of renal function in the context of recent achievements in molecular biology and genetics are discussed.
Characterization of metallic studs used in gypsum board single frame walls

This work aims to characterize metallic studs used in gypsum board single frame walls. The sound reduction index associated to the direct path (cavity path) of the double wall can be calculated using a wave based transfer matrix approach. In the mid-high frequency range, an SEA approach is preferred to model the frame between the two gypsum leaves, as point connections modeled by punctual springs defined by its translational stiffness located at the screws position on the frame. An experimental setup has been proposed to determine the equivalent stiffness of the stud at the screw positions. Based on these data predicted and measured sound reduction index are in fairly good agreement. In the present work, a finite element model corresponding to the experimental setup is developed to characterize metallic studs in order to perform a parametric study and investigate new studs shape. The effects of the material physical characteristic variations, the dimensions and metal thickness, and the shape of the studs as well as the type and number of gypsum board mounted on the frame are presented and discussed.
Makwe & Giwa-Osagie Sexuality and RH, in HIV Discordant Couples

Serodiscordant couples are a significant source of new HIV infection in sub-Sahara Africa. The prevention of HIV transmission to the uninfected partner should be an integral part of their health care. Serodiscordant couples desire pregnancy, treatment for infertility, effective family planning services, sexual health screening, and so on. This paper reviews the sexual and reproductive health needs of heterosexual serodiscordant couples, based on current evidence and recommendations. Afr J Reprod Health 2013 (Special Edition); 17[4]: 99-106).
-Investigating whether short-sellers exploit accounting-based pricing anomalies

This paper examines whether short-sellers (bears) exploit post-earnings-announcement-drift (PEAD) and the accruals anomaly. I first find that short interest is higher during the period that follows a negative earnings surprise and, to a lesser extent, the announcement of earnings that contains an abnormal income-increasing accrual component. Second, holding both anomalies constant, I find that prices decline more quickly in the presence of higher short interest. However, I do not find that higher short interest improves the pricing of information about future earnings contained in current earnings.
A QUEST TO PREVENT PASSWORD FLOGGING ISSUES USING QRP THROUGH ANDROID BASED AUTHENTICATION

---In any online service that aims to be secure nowadays should seriously consider implementing a strong authentication method. Nowadays there are numerous key logging methods that are available to steal the user credentials. Key logging is an activity of capturing users’ keyboard strokes and records the activity of a computer user using key logger hardware and software. It can be used to intercept passwords and other confidential information’s such as email passwords PIN codes, account numbers entered via the keyboard by considering various rootkits residing in PCs that breaches the security. As a result, it impersonates a user during authentication in financial transactions. We propose QR pattern based mechanism which can be used to design a visual authentication protocol to achieve high usability and security. Through accurate analysis, this protocol is proved to be robust to several authentication attacks. And also by deploying these protocol in real-world applications especially in online transactions, the strict security requirements can be satisfied.
STAT3 and MAPK signaling maintain overexpression of heat shock proteins 90 (cid:1) and (cid:2) in multiple myeloma cells, which critically contribute to tumor-cell survival

The combined blockade of the IL-6R/ STAT3 and the MAPK signaling pathways has been shown to inhibit bone marrow microenvironment (BMM)–mediated sur-vivalofmultiplemyeloma(MM)cells.Here, weidentifythemolecularchaperonesheat shock proteins (Hsp) 90 (cid:1) and (cid:2) as target genes of both pathways. The siRNA-mediated knockdown of Hsp90 or treatment with the novel Hsp90 inhibitor 17-DMAG attenuated the levels of STAT3 and phospho-ERK and decreased the viability of MM cells. Although knockdown of Hsp90 (cid:2) —unlike knockdown of Hsp90 (cid:1) — was sufﬁcient to induce apoptosis, this effect was strongly increased when both Hsp90s were targeted, indicating a coop-eration of both. Given the importance of the BMM for drug resistance and MM-cell survival, apoptosis induced by Hsp90 inhibition was not mitigated in the presence ofbonemarrowstromalcells,osteoclasts, or endothelial cells. These observations suggest that a positive feedback loop consisting of Hsp90 (cid:1) / (cid:2) and major signaling pathways supports the survival of MM cells. Finally, in situ overexpression of both Hsp90 proteins was observed in most MMs but not in monoclonal gammopathy of undetermined signiﬁcance (MGUS) or in normal plasma cells. Our results underpin a role for Hsp90 (cid:1) and (cid:2) in MM pathogenesis. (Blood. 2007;109: 720-728)
Prognostic signiﬁcance of surgical-pathologic multiple-station N1 disease in non-small cell carcinoma of the lung q

Objectives : The surgical outcome of pathologic N1 disease in resectable non-small cell lung carcinoma (NSCLC) is controversial. The prognosis of the patients with multiple/bulky N2 disease was invariably dismal. However, the prognostic signiﬁcance of tumor involvement in more than one hilar or intralobar lymph node station has not been fully described. Methods : From 1996 to 2002, 181 patients with NSCLC had complete resection. Four levels of N1 nodes and N2 nodes were identiﬁed using the new regional lymph node classiﬁcation for lung cancer staging. There were 67 patients (37%) with no nodal disease (N0), 43 patients (24%) with N1 and 71 patients (39%) with N2 disease. The N1 subgroup cases were reviewed. The prognostic signiﬁcances of single and multiple N1 diseases were tested. Results : The cumulative postoperative survival at 3 and 5 years was 57 and 29%, respectively. The survival associated with single-station N1 disease was signiﬁcantly better than that of multiple-station N1 disease (45 vs 32% at 5 years; P ¼ 0 : 03). Five-year survival was similar in patients with multiple N1 disease and patients with single-station N2 involvement (32 vs 31% at 5 years; P ¼ 0 : 84). However, no patient survived when tumor was detected in more than one mediastinal station (i.e. multiple N2 disease). Conclusions : It was suggested that N1 disease is a compound of two subgroups: one involving in one node and the other (multiple N1 disease) in which the postoperative prognosis was not statistically different from that of N2 disease.
Eliminating the Variability of Cross-Validation Results with LIBLINEAR due to Randomization and Parallelization

Cross-validation is the gold standard for evaluating machine learning algorithms or fine-tuning their parameters. The results of this technique, however, are not always reproducible and may depend on the computing platform and the number of parallel threads, especially if the underlying learning algorithm uses a pseudo-random number generator (PRNG). This paper gives a recipe for solving these reproducibility problems and applies it to LIBLINEAR 1 , a popular software library that implements randomized learning algorithms based on support vector machines 2 . The proposed approach solves these problems by using a cross-platform PRNG and by making the PRNG state private in each thread. The cross-validation results obtained with the modified version of LIBLINEAR are the same across platforms. Furthermore, the parallelized cross-validation results are no longer affected by random fluctuations arising from the sharing of the PRNG state by parallel threads.
Development of a single-scale initial flow field into steady homogeneous turbulence with validating a constructed Fourier spectral analysis

This study presents the development of a single-scale initial velocity field into steady homogeneous isotropic turbulence. Here, we verify a constructed Fourier spectral analysis, which is then used to approach the present issue. The present homogeneous isotropic turbulence is maintained steady by using a linear forcing scheme of Lundgren (2003). Here, two values of the primary coefficient are set here for this scheme. The initial velocity field is also set to maintain the flow globally isotropic. Temporal developments of turbulence statistics, visualization results and structure functions are examined in this study. As shown in a previous study, Rosales and Meneveau (2005), the turbulence length scale at a steady-state could remain independent of a value used for the linear forcing coefficient. The turbulence fields needed 10 to 15 times longer than the turbulence time scale to achieve this steady-state. A larger amount of time was needed for the structure functions to reach their steady-state profiles than for the turbulence statistics.