Miracle-dz/UniFAR-FTUs huggingface dataset:
VHRM_A_283211 175..185

1Cardiovascular Research Center, Faculty of Medicine and Health, Örebro University, Örebro, 70182, Sweden; 2Department of Physical Activity and Health, The Swedish School of Sport and Health Sciences, GIH, Stockholm, 11433, Sweden; 3The Biomedical Platform, Department of Natural Science and Biomedicine, School of Health and Welfare, Jönköping University, Jönköping, 55111, Sweden Purpose: Arterial stiffness describes the rigidity of the arterial walls and is associated with risk factors for cardiovascular disease (CVD). Arterial stiffness predicts future events and mortality, and the predictive value is stronger in younger versus older subjects. The aims of the present study were, firstly, to present data on physical activity (PA) and time spent sedentary, in the population of Swedish, young adults. Secondly, to explore the association between PA and arterial stiffness. Material and Methods: Self-reported healthy, non-smoking, Swedish, young adults, 18–25 years old, participated in the cross-sectional Lifestyle, Biomarkers and Atherosclerosis (LBA) study. The daily PA was objectively measured with an accelerometer for 1 week. Of the 834 participants, 658 individuals had valid registrations. The arterial stiffness measures, pulse wave velocity (PWV) and augmentation index (AIx) were measured with applanation tonometry. Results: Women were on overall more physically active than men, they spent 214 min/day in light PA (LPA) compared to men who spent 202 min/day. Women took significantly more steps per day than men, 7796 vs 7336 steps/day, and spent less time sedentary, 523 min/day, compared to men who spent 547 min/day sedentary. In total, 76% of the individuals spent on average at least 30 minutes per day in the recommended moderate and vigorous PA (MVPA). Lower arterial stiffness was associated with more MVPA and total PA in the total population. Conclusion: We conclude that in this age group of young, self-reported healthy adults 18–25 years, it is important to highlight the health-enhancing possibilities of time spent in physical activity on the vascular function, measured as PWV and AIx. It is of high relevance in a public health perspective to expand preventive efforts beyond the high-risk groups and encourage young adults to be physically active.
G ENETIC M ATING S YSTEMS AND R EPRODUCTIVE N ATURAL H ISTORIES OF F ISHES : Lessons for Ecology and Evolution

n Abstract Fish species have diverse breeding behaviors that make them valuable for testing theories on genetic mating systems and reproductive tactics. Here we review genetic appraisals of paternity and maternity in wild ﬁsh populations. Behavioral phenomena quantiﬁed by genetic markers in various species include patterns of multiple mating by both sexes; frequent cuckoldry by males and rare cuckoldry by females in nest-tending species; additional routes to surrogate parentage via nest piracy and egg-thievery; egg mimicry by nest-tending males; brood parasitism by helper males in cooperative breeders; clutch mixing in oral brooders; kinship in schooling fry of broadcast spawners; sperm storage by dams in female-pregnant species; and sex-role reversal, polyandry, and strong sexual selection on females in some male-pregnant species. Additional phenomena addressed by genetic parentage analyses in ﬁshes include clustered mutations, ﬁlial cannibalism, and local population size. All results are discussed in the context of relevant behavioral and evolutionary theory. Local Population
Character Building or The Development of the Personality: An Innovative Methodological Platform in the Informational Educational Space

: Currently an acute crisis exists regarding the traditional methodological platform of the higher education system. Research continues with studies of individual facets of human personality without re-ferring to new methodological realities. The dominant model of the University has remained unchanged for about 200 years. Today, however, the goals, means and agents of socialization are changing. In this es-say, a new methodological platform for personality development is proposed and discussed, one which ex-amines the role of behavioral stereotypes in the social and professional success of the individual. Charakterbildung
A novel negative regulatory function of PAG: blocking Ras activation.

In primary human T-cells, anergy induction results in enhanced p59Fyn activity. Since Fyn is the kinase primarily responsible for the phosphorylation of PAG (the phosphoprotein associated with glycosphingolipid-enriched microdomains), which negatively regulates Src-kinase activity by recruiting Csk (the C-terminal Src kinase) to the membrane, we investigated whether anergy induction also affects PAG. Analysis of anergic T-cells revealed that PAG is hyperphosphorylated at the Csk binding site, leading to enhanced Csk recruitment and inhibitory tyrosine phosphorylation within Fyn. This together with enhanced phosphorylation of a tyrosine within the SH2 domain of Fyn leads to the formation of a hyper-active conformation, thus explaining the enhanced Fyn kinase activity. Additionally, we have also identified the formation of a multi-protein complex containing PAG, Fyn, Sam68, and RasGAP in stimulated T-cells. We demonstrate that PAG-Fyn over-expression is sufficient to suppress Ras activation in Jurkat T-cells and show that this activity is independent of Csk binding. Thus, in addition to negatively regulating Src family kinases by recruiting Csk, PAG also negatively regulates Ras by recruiting RasGAP to the membrane. Finally, by knocking down PAG, we demonstrate both enhanced Src kinase activity and Ras activation, thereby establishing PAG as an important negative regulator of T-cell activation. Its phosphorylation by Fyn is dependent upon the binding of the Fyn SH3 domain to Sam68.
ACANTHOGYRUS TILAPIAE INFECTIONS IN WILD AND CULTURED NILE TILAPIA OREOCHROMIS NILOTICUS

Acanthogyrus tilapiae (Baylis, 1948) was isolated from the intestines of wild (from River Nile) and cultured (from ponds beside River Nile) Nile tilapia Oreochromis niloticus in Assiut city, Egypt. The study extended over one year starting from December 2013 to November 2014. The overall infection rate was 12.84%, while was 11.80% with a mean intensity of 4.70 in the wild fish, and was 13.19% with a mean intensity of 2.68 in the cultured fish. The highest infection rate was recorded in winter in both wild (36.1%) and cultured (33.3%) fish. Males have insignificantly higher infection rates than females in both wild and cultured fish. There was a positive correlation between fish length (age) and A. tilapiae infection rates where larger (older) fish showed significantly higher infection rates then younger fish. The parasite was found mainly in the anterior two thirds of the intestine with the lowest number of the parasite detected in the posterior third. Histopathologically, the intestine of fish infected showed parasitic enteritis with lytic necrosis in the intestinal mucosa which associated with eosinophilic
Thrombospondin-1 (TSP1) is an adipokine associated with obesity, adipose inflammation and insulin resistance

Objectives: We examined the relationship between the expression of thrombospondin-1 (TSP1), an anti-angiogenic factor and regulator of TGF- β activity, with obesity, adipose inflammation and insulin resistance. Research Design and Methods: TSP1 gene expression was quantified in subcutaneous adipose tissue (SAT) of 86 non-diabetic subjects covering a wide range of BMI and insulin sensitivity, from visceral adipose (VAT) and SAT from 14 surgical patients, and from 38 subjects with impaired glucose tolerance randomized to receive either pioglitazone or metformin for 10 weeks. An adipocyte culture system was also used to assess the effects of pioglitazone and co-culture with macrophages on TSP1 gene expression. Results: TSP1 mRNA was significantly associated with obesity (BMI) and insulin resistance (low S I ). Relatively strong positive associations were seen with markers of inflammation, including CD68, MCP1 and PAI-1 mRNA (r>0.46, p=0.001 for each), that remained significant after controlling for BMI and S I . However, TSP1 mRNA was preferentially expressed in the adipocyte fraction, whereas inflammatory markers predominated in the stromal vascular fraction. Co-culture of adipocytes and macrophages augmented TSP1 gene expression and secretion from both cell types. Pioglitazone (not metformin) treatment resulted in a 54% decrease (p<0.04) in adipose TSP gene expression, as did in vitro pioglitazone treatment of adipocytes. Conclusion: TSP1 is a true adipokine that is highly expressed in obese, insulin resistant subjects, highly correlated with adipose inflammation, and decreased by pioglitazone. TSP1 is an important link between adipocytes and macrophage-driven adipose tissue inflammation and may mediate the elevation of PAI-1 that promotes a pro-thrombotic state.
COMPARATIVE BOTANICAL STUDIES ON TWO NEWLY TOMATO GENOTYPES AS AFFECTED BY WASTEWATER AND SHADING: I. MORPHOLOGICAL CHARACTERS.

Two field experiments were carried out at the Agric. Experimental Agric. , Mansoura University, Egypt during the two growing seasons of 2007-2008 and 2008-2009, aiming to evaluate botanically two newly tomato genotypes grown under shading and wastewater of El-Delta company of fertilizers and Talkha electricity generate mixed with sewage of the vicinity villages, at Dakahlia Governorate, Egypt. The data indicated that Cheyenne (e 448) genotypes recoded an increase in all growth characters studied compared with Gs 12 at different growth stages in both growing seasons. However, in both genotypes, Plant height, numbers of internodes, leaves and branches on the main stem, as well as, fresh and dry weight of the shoot system were increased significantly due to wastewater application at 50% level whereas decreased insignificantly at 100% level. Shading agent seemed to have a stimulating effect on different growth characters of the two tomato genotypes under the present investigation compared with the control The interaction treatments indicated that shading enabled the developing tomato plants to withstand, wastewater at 100% level . The "S" or sigmoide growth curve was detected in both tomato genotypes studied during the two tomato growing seasons. The highest rate of increase was detected between the 1 st and 2 nd sampling date. days and at 100% hasten following by about 12-15 days in the first and second seasons respectively. Shading with wastewater at 100% has no significant effect in this respect
ANALYSIS OF DIFFERENT RISKS OF COMPLICATIONS OF PREGNANCY IN WOMEN WITH TYPE 1 DIABETES

: Introduction: Type 1 diabetes holding pregnant women are also associated with a highly increased risk of congenital malformations, neonatal morbidity, and obstetric complications. These highly adverse results are related to pre-conceptional care typically related to the glycaemic control level. Aims and objectives: The basic aim of the study is to analyze different Risks of Complications of Pregnancy in Women with Type 1 Diabetes. Material and methods: This study was conducted in Punjab Health Department, Pakistan. Record gathered from 118 hospitals with the total number of 364 women stated for the study coordinator. As per database record, 11% (41 women) were excluded due to initial trimester spontaneous abortion as well as type 2 diabetes diagnosed in 16; 4% and follow up loss 2; 1%. We also stated the assessment of 323 pregnancies and all respondents gave written apprised consent. Entitled women completed questionnaires at inclusion (at the end of the initial trimester and around gestation of ten weeks) but during the trimester three (which is almost around 34 weeks). Results: Maternal outcomes in pregnant women with type 1 diabetes and those without the disease were evaluated in this study. No maternal mortality occurred within 30 days of delivery in 630 pregnancies with type 1 diabetes. However, pregnant women with type 1 diabetes were usually at a much higher risk of developing adverse maternal events during their pregnancy than women without type 1 diabetes, even after adjusting for age and infant sex or age, infant sex, place of residence, income level, occupation, calendar year, and Charlson comorbidity index. The risks of preeclampsia, eclampsia and cesarean delivery, increased in
Inhibition of luteolysis and embryo-uterine(cid:10) interactions during the peri-implantation period in(cid:10) pigs

Inhibition of luteolysis and establishment of pregnancy in pigs results from oestrogen secretion by the conceptuses and requires progesterone produced by the corpus luteum (CL). An integral part of maternal recognition of pregnancy in the pig is the redirection of prostaglandin (PG) F2c, secretion from endocrine (blood) to exocrine (uterus) direction and an increase of PGE2 synthesis in both the endometrium and conceptus. Uterine and conceptus PGE2 synthases play an integrated role in establishing the PGE2:PGF20 ratio necessary for luteal maintenance. The luteolytic or luteotrophic changes in the CL are synchronised with the release of maternal pituitary and ovarian hormones. The presence of uterine oxytocin (OT) and luteinising hormone (LH) receptors are important for the luteolytic effect of PGF2a. Conceptus oestrogen secretion coincides with autocrine and paracrine dialogue between the multiple conceptuses and uterine biological compounds and their receptors in trophoblast and endometrium. in the
An Hybrid Approach in Classification of Telugu Sentences

: Natural Language Processing (NLP) is a multidisciplinary research area that explores how computer understand human language in the form of text or speech to do useful things. Telugu is most prominent and morphologically rich dravidian language spoken by around one million people. When research in computational linguistics is concerns telugu is far behind other south Indian languages . Recognizing sentence similarity is most useful task in all the languages which are useful for improving plagiarism detection of documents, word sense disambiguation, query evaluation, paraphrase detection and question answering. In this paper, we discuss an hybrid approach to calculate semantic similarity score between two telugu sentences using supervised learning for classifying simple telugu verb less sentences using linguistic knowledge of telugu language and combination of rule based and stochastic methods are used to measure similarity between sentences.
The Logic Summer School 2004

: Abstract Logic is the foundational discipline of many sciences. Part mathematics, part philosophy and part computing science, logic remains a core intellectual study and is increasingly relevant to practical concerns. It spreads into planning, into program synthesis, into circuit design and into discourse analysis. It underpins the entire science of artiﬁcial intelligence. In order to increase knowledge from the ﬁeld of logic, I participated in the Logic Summer School. This report covers some information.
Analysis of Classification Algorithms for Heart Disease Prediction and its Accuracies

: Heart disease is the leading cause of death and it is necessary to predict it at earlier stages to save the life of human beings. Many researchers proposed number of data mining algorithms to predict the heart disease. Different algorithms gives various levels of accuracies. Here I am comparing the accuracies of few classification algorithms Random Tree, Naïve Bayes, Decision Tree and Random forest. The Hungarian_csv database with 294 instances and 14 attributes age, sex, cp, trestbps, chol, fbs, restecg, talach, exang, oldpeak, slope, ca, thal and num were used here for the analysis. RapidMiner Software is used to experiment the collected datasets. It is a software platform developed by the company of the same name that provides an integrated environment for machine learning, data mining, text mining, predictive analytics and business analytics. The collected datasets are passed as input to the above mentioned classification algorithms and the result obtained is analyzed and different views. It is found that Naïve Bayes gives the best accuracy of 79.25% with next 78.24% of accuracy by Decision Tree. Random tree gives 75.14% accuracy while Random forest stands next with 74.16%. The different measures and results were tabulated and charted
A praenatalis és postnatalis mikrobiom jelentősége és hatásai a korai egyedfejlődés időszakában és az intervenciós kezelés lehetőségei

interacts with the maternal immune system through the effects of environmental stimuli through the mother. Many maternal factors, including hormones, cytokines, and the microbiome, can modify the intrauterine environment, thereby affecting the development of the fetal immune system. Infants of mothers under increased stress have higher rates of allergies and gastrointestinal disorders. The diet of the gravida also affects the fetal microbiome through the uterus. Our intestinal flora, or microbiome, is the totality and symbiosis of the microbes living in them, the delicate balance of which is established in infancy and decisively determines the functioning of the intestinal barrier and the intestinal associated immune system. The prebiotic required for the proliferation of probiotics can also affect the intestinal flora. The combination of pre- and probiotic is symbiotic. Breast milk has a protective effect against patho-gens, in part by raising the number of Bifidobacteria in the intestinal flora of the newborn. Dysbiosis is a change in the commensal, healthy gut flora. Its role is hypothesized in functional gastrointestinal disorders, as well as in more and more psychiatric and neurological disorders such as the autism spectrum disorder.
INTERACTION BETWEEN ORAL DISEASES AND OTHER HEALTH-RELATED FACTORS

About 30% of male infertility cases are idiopathic. Previous studies reported a positive correlation between deep periodontal pockets and sperm sub-motility, which suggests that periodontitis might have a role in idiopathic semen abnormality pathospermia. We evaluated correlations between periodontal infection parameters and the results of sperm analysis of men with idiopathic infertility. In this observational study, semen quality and periodontal status were analyzed for 95 otherwise healthy men attending an andrology unit for sperm analysis. Half the men in the sperm pathology and normozoospermia groups (50.8% and 50%, respectively) had poor periodontal status. Among the 95 participants, 38% had oligozoospermia, 28% had asthenozoospermia, 16% had cryptozoospermia, and 15% were classified as normozoospermic. Sperm pathology category was not associated with frequency of deep periodontal pockets or calculus. Bleeding on probing was significantly lower among men with asthenozoospermia than among those with normozoospermia. Poor periodontal status was not associated with any sperm pathology category or parameter. In contrast with previous findings, the present results indicate that pathospermia and poor semen quality are not associated with periodontal infection in men with idiopathic infertility. (J Oral Sci 58, 247-253, 2016)
Reactive Oxygen Species and Red Ox State During In Vitro Fertilization

It has been shown that several transcription factors involved in developmental processes are regulated by the intracellular red ox potential [21-26]. These factors are sensitive to oxidation or S-glutathionylation by ROS and require NAD (P) H o NAD (P)+ [27]. In somatic cells, it has been observed that red ox state and ROS levels are negatively related. A high intracellular oxidative activity (for example, due to the increase in the mitochondrial oxygen consumption rate) is usually associated with a decrease in ROS production [28]. In the mouse, it has been demonstrated that redox state and ROS production regulation have a fundamental importance in early embryo development [27].
Studying Depth in a 3D User Interface by a Paper Prototype as a Part of the Mixed Methods Evaluation Procedure Early Phase User Experience Study

— A principal characteristic of three dimensional user interfaces is that it contains information in the 3rd axis. Visually, this information is presented as being placed further away from the screen or having depth. A consequence of this is that information can be occluded. Determining the optimal amount of depth levels for specifically sized icons is important in the design of 3D user interfaces. This paper investigates the depth placement of objects of a three dimensional user interface on a tablet device at the early stage of the development process. We present mixed methods evaluation with a paper prototype with a focus on the users' subjective experiences. Users were presented with concepts of different depth levels, with and without 3D objects. The findings indicate that users' preference was for depth levels 3-5. We recommend designing 3D UIs with a controllable depth by starting with a few depth levels and increasing them automatically based on the amount of 3D objects. Also, it is important to give a user a possibility to customize depth levels when needed. This paper provides user preference information on depth for 3D UI designers and developers, especially in the context of a touch screen tablet device.
Whole-head functional brain imaging of neonates at cot-side using time-resolved diffuse optical tomography

We present a method for acquiring whole-head images of changes in blood volume and oxygenation from the infant brain at cot-side using time-resolved diffuse optical tomography (TR-DOT). At UCL, we have built a portable TR-DOT device, known as MONSTIR II, which is capable of obtaining a whole-head (1024 channels) image sequence in 75 seconds. Datatypes extracted from the temporal point spread functions acquired by the system allow us to determine changes in absorption and reduced scattering coefficients within the interrogated tissue. This information can then be used to define clinically relevant measures, such as oxygen saturation, as well as to reconstruct images of relative changes in tissue chromophore concentration, notably those of oxy- and deoxyhaemoglobin. Additionally, the effective temporal resolution of our system is improved with spatio-temporal regularisation implemented through a Kalman filtering approach, allowing us to image transient haemodynamic changes. By using this filtering technique with intensity and mean time-of-flight datatypes, we have reconstructed images of changes in absorption and reduced scattering coefficients in a dynamic 2D phantom. These results demonstrate that MONSTIR II is capable of resolving slow changes in tissue optical properties within volumes that are comparable to the preterm head. Following this verification study, we are progressing to imaging a 3D dynamic phantom as well as the neonatal brain at cot-side. Our current study involves scanning healthy babies to demonstrate the quality of recordings we are able to achieve in this challenging patient population, with the eventual goal of imaging functional activation and seizures.
Small and medium enterprises in Russia and other countries

The aim of the study was a comparative analysis of the activities of small and medium-sized enterprises in Russia and foreign countries. The article presents the principles and concepts of entrepreneurship. The distribution of small and medium-sized enterprises by types of economic activity is considered. Data of continuous surveys of activity of entrepreneurship of Russia in 2010 and 2015 were used as initial data. A comparison of the share of small and medium-sized enterprises in the economy of Russia and foreign countries is presented. The results of the study can be used by the departments of regional and municipal authorities engaged in the formation of projects and programs for the development of entrepreneurship, including the development of entrepreneurship in those regions and municipalities. The study is able to provide the government with information on ways to increase the contribution of enterprises to the national economy.