Miracle-dz/UniFAR-FTUs huggingface dataset:
Simple and Sensitive Method for the Quantitative Determination of Lipid Hydroperoxides by Liquid Chromatography/Mass Spectrometry

Lipid hydroperoxides (LOOH) are the initial products of the peroxidation of unsaturated lipids and play a crucial role in lipid oxidation due to their ability to decompose into free radicals and cause adverse effects on human health. Thus, LOOHs are commonly considered biomarkers of oxidative stress-associated pathological conditions. Despite their importance, the sensitive and selective analytical method for determination is limited, due to their low abundance, poor stability, and low ionizing efficiency. To overcome these limitations, in this study, we chemically synthesized eight fatty acid hydroperoxides (FAOOH), including FA 18:1-OOH, FA 18:2-OOH, FA 18:3-OOH, FA 20:4-OOH, FA 20:5-OOH, FA 22:1-OOH, FA 22:6-OOH as analytes, and FA 19:1-OOH as internal standard. Then, they were chemically labeled with 2-methoxypropene (2-MxP) to obtain FAOOMxP by one-step derivatization (for 10 min). A selected reaction monitoring assisted targeted analytical method was developed using liquid chromatography/tandem mass spectrometry (LC-MS/MS). The MxP-labelling improved the stability and enhanced the ionization efficiency in positive mode. Application of reverse-phase chromatography allowed coelution of analytes and internal standards with a short analysis time of 6 min. The limit of detection and quantification for FAOOH ranged from 0.1–1 pmol/µL and 1–2.5 pmol/µL, respectively. The method was applied to profile total FAOOHs in chemically oxidized human serum samples (n = 5) and their fractions of low and high-density lipoproteins (n = 4). The linoleic acid hydroperoxide (FA 18:2-OOH) and oleic acid hydroperoxide (FA 18:1-OOH) were the most abundant FAOOHs in human serum and lipoproteins. Overall, our validated LC-MS/MS methodology features enhanced detection and rapid separation that enables facile quantitation of multiple FAOOHs, therefore providing a valuable tool for determining the level of lipid peroxidation with potential diagnostic applications.
The Assessment of Prolonged Inferior Alveolar Nerve Blockade for Postoperative Analgesia in Mandibular Third Molar Surgery by a Perineural Addition of Dexamethasone to 0.5% Ropivacaine: A Randomized Comparison Study

Background: Perineurally adding dexamethasone to local anesthetics could enable postoperative analgesia. Our aim was to investigate the efficacy of 4 mg dexamethasone and 0.5% ropivacaine on the prolonged duration of mandibular anesthesia for postoperative analgesia during third molar surgery. Materials and method: The patients of both sexes, and in the age range of 17 to 50 yrs of age, received the Gow-Gates anesthesia. Group I received 4 mL of plain 0.5% ropivacaine, with perineurally added 1 mL/4 mg of dexamethasone; group II received 4 mL of plain 0.5% ropivacaine with perineurally added 1 mL of 0.9% saline; group III received 4 mL of plain 0.5 bupivacaine with perineurally added 1 mL of 0.9% saline. The prime anesthesia outcome was the duration of conduction anesthesia (DCA); the secondary outcome was the duration of analgesia (DAN) and analgesia before analgesic intake. Results: In 45 randomly selected subjects (mean age 27.06 ± 8.20), DCA was statistically longest in group I (n = 15) (592.50 ± 161.75 min, p = 0.001), collated with groups II (n = 15) and III (n = 15) (307.40 ± 84.71 and 367.07 ± 170.52 min, respectively). DAN was significantly the longest in group I (mean: 654.9 ± 198.4 min, p = 0.001), compared with group II (345.4 ± 88.0 min) and group III (413.7 ± 152.3 min), with insignificant adverse reactions. One-third of the operated patients absented from the use of analgesics. Conclusion: A amount 0.5% ropivacaine with dexamethasone usefully served as an analgesic with a success rate of 93.4% of the given anesthesia.
Winning Results with Google Ad Words

Don’t get lost in the digital haystack! With thousands of links for every search, the chances of your products being found online are slimmer than a needle. But there’s good news: you can pinpoint your marketing message with help from Winning Results with Google AdWords. You'll discover AdWord essentials, how to bid for and win the keywords you want, how to track your results, and much more. Create a profitable ad campaign using online marketing, paid search, targeting, and leveraged branding.
lncRNA MSC-AS1 Aggravates Diabetic Nephropathy by Regulating the miR-325/CCNG1 Axis

Background Diabetic nephropathy (DN) is the most common microvascular complication of diabetes and has become the second leading cause of end-stage renal disease in the world. This study aims to clarify the regulatory mechanism of the lncRNA MSC-AS1/miR-325/cyclin G1 (CCNG1) axis in DN. Methods The regulatory mechanism of lncRNA MSC-AS1/miR-325/CCNG1 was evaluated by RT-qPCR, CCK-8 assay, flow cytometry assay, RNA pull-down assay, ELISA, and western blot assay. Results Upregulation of lncRNA MSC-AS1 was detected in DN patients and HRMC cells treated with high glucose (HG). Knockdown of lncRNA MSC-AS1 reduced the proliferation, fibrosis, and inflammation of HRMC cells induced by HG. In addition, lncRNA MSC-AS1 acts as a miR-325 sponge in the DN. CCNG1 is the direct target of miR-325, which can be positively regulated by lncRNA MSC-AS1 in DN. More importantly, downregulation of miR-325 and upregulation of CCNG1 can attenuate the protective effect of lncRNA MSC-AS1 knockdown on DN. Conclusion lncRNA MSC-AS1 aggravates DN by downregulating miR-325 and upregulating CCNG1.
Hybrid Bead Air Filters with Low Pressure Drops at a High Flow Rate for the Removal of Particulate Matter and HCHO

A tower air filtration system was designed in which bead air filters (BAFs) were actively rotated by a fan motor to remove particulate matter (PM) or HCHO gas. Three types of BAF, hydrophilic, hydrophobic, and hybrid, were prepared and compared for the removal of PM and HCHO gas. A tower air filtration system loaded with hybrid BAFs purified 3.73 L of PM (2500 μg/m3 PM2.5) at a high flow rate of 3.4 m/s with high removal efficiency (99.4% for PM2.5) and a low pressure drop (19 Pa) in 6 min. Against our expectations, the PM2.5 removal efficiency slightly increased as the air velocity increased. The hybrid BAF-200 showed excellent recyclability up to 50 cycles with high removal efficiencies (99.4–93.4% for PM2.5). Furthermore, hydrophilic BAF-200 could permanently remove 3.73 L of HCHO gas (4.87 ppm) and return the atmosphere to safe levels (0.41–0.31 ppm) within 60 min without any desorption of HCHO gas.
Zero-voltage-transition bridgeless power factor correction rectifier with soft-switched auxiliary circuit

This study presents a zero-voltage-transition (ZVT) bridgeless power factor correction (PFC) rectifier, which uses an auxiliary circuit with a transformer to achieve soft-switching for the main power switches. With the auxiliary circuit, the main switches can be ZVT turned-on without any additional voltage or current stresses. In addition, the auxiliary switch is turned-off with zero-current switching. Therefore, the switching loss of all power switches is reduced, and the overall rectifier efficiency is improved. The circuit topology, operation analysis and the components selection of the proposed rectifier are described in detail. Finally, a laboratory prototype of 700 W is implemented and tested to verify the performance of the proposed PFC rectifier.
Enhancing the Biocontrol Potential of the Entomopathogenic Fungus in Multiple Respects via the Overexpression of a Transcription Factor Gene MaSom1

Entomopathogenic fungi play important roles in the control of populations of agricultural and disease vector pests in nature. The shortcomings of mycoinsecticides for pest management in the field cannot be completely overcome by improving single biocontrol properties of fungi. Therefore, enhancing the biocontrol potential of entomopathogenic fungi in multiple respects by genetic engineering is desirable. Transcription factors are usually involved in various important processes during fungal growth and pathogenesis via regulating a series of genes, and are important candidates for fungal improvement via genetic engineering. Herein, overexpression of MaSom1, a key transcription factor gene in the cAMP/PKA pathway, improves the biocontrol traits of Metarhizium acridum in multiple respects. When compared with WT, the MaSom1-overexpression strains exhibit enhanced tolerances to UV-B and heat shock, with increased mean 50% inhibition times by 66.9% and 155.2%, respectively. Advanced conidiation emerged accompanied by increased conidial yield up to 3.89 times after 3-day incubation for the MaSom1-overexpression strains compared to WT. Furthermore, when compared with WT, the virulence of the MaSom1-overexpression strains was also increased with the mean 50% lethality times reduced by 21.8% to 23.8%. Taken together, the MaSom1-overexpression improved the biocontrol potential of M. acridum in multiple respects. Our results provide insights into the application of key transcription factors for genetic engineering and offer a credible way to further improve the biocontrol potential of entomopathogenic fungi.
Predicting Battery Life for Electric UAVs

This paper presents a novel battery health management technology for the new generation of electric unmanned aerial vehicles powered by long-life, high-density, scalable power sources. Current reliability based techniques are insufficient to manage the use of such batteries when they are an active power source with frequently varying loads in uncertain environments. The technique presented here encodes the basic electrochemical processes of a Lithium-polymer battery in an advanced Bayesian inference framework to simultaneously track battery state-of-charge as well as tune the battery model to make accurate predictions of remaining useful life. Results from ground tests with emulated flight profiles are presented with discussions on the use of such prognostics results for decision making.
Conceptualizing Stakeholders’ Perceptions of Ecosystem Services: A Participatory Systems Mapping Approach

Abstract A participatory system dynamics modelling approach is advanced to support conceptualization of feedback processes underlying ecosystem services and to foster a shared understanding of leverage intervention points. The process includes systems mapping workshop and follow-up tasks aiming at the collaborative construction of causal loop diagrams. A case study developed in a natural area in Portugal illustrates how a stakeholder group was actively engaged in the development of a conceptual model depicting policies for sustaining the climate regulation ecosystem service.
Moving, Fast or Slow: How Perceived Speed Influences Mental Representation and Decision Making

Can the sensation of moving fast versus slow systematically influence consumer behavior? With recent technological innovations, people increasingly experience speed during decision making. They can be physically on the move with their devices or virtually immersed in speed simulated through their devices. Through seven experiments, we provide evidence for a speed-abstraction effect, where the perception of moving faster (vs. slower) leads people to rely on more abstract (vs. concrete) mental representations during decision making. This effect manifests for virtually simulated (experiment 1) and physically experienced (experiment 2) movement on moving trains. We suggest that it stems from an underlying speed-abstraction schema where people associate faster speed with abstraction and slower speed with concreteness (experiments 3a-3c). Weakening this schema attenuates the effect (experiment 4). Through a field study, experiment 5 demonstrates that video ads placed on Facebook are more engaging when virtually simulated speed matches the linguistic abstraction level of the message. Dimensions of psychological distance (time, space) and factors influencing mental representation (affect, fluency, spatial- orientation) are addressed as possible alternative explanations that cannot account for the effect. We propose a framework for understanding how experiencing speed—both physical and virtual—can influence decision making.
Employee Engagement of Teaching Faculty Members in Higher Educational Institutions in Bengaluru

Abstract: In this paper attempted to analyse Employee engagement of teaching faculty members in higher educational institutions. Dynamic work place environments require employee work engagement. Employee engagement refers to the degree to which employees are focused on and present in their roles. In today’s competitive framework of work place environment employees may reach their cognitive and motivational limits and this may strain employees’ attentiveness and engagement. This paper reviews research studies on employee engagement and performance link. Work Culture of today in Educational Institutions requires active engagement of teachers which affects their performance. Keywords: Employee Engagement, Work Engagement, Job Performance, Educational Institutions
Hubungan Karakteristik Perawat dan Safety Attitude di Rumah Sakit Jakarta

Sikap keselamatan perawat mempengaruhi tindakan dalam menerapkan implementasi asuhan keperawatan yang berbasis keselamatan pasien. Penelitian ini bertujuan mengetahui hubungan karakteristik perawat dan sikap keselamatan, melalui penelitian cross sectional yang melibatkan 330 perawat di 3 rumah sakit veritkal Jakarta. Instrumen yang digunakan adalah Safety Attitudes Questionnaire dengan tambahan data demografi. Terdapat hubungan signifikan antara karaktersitik perawat dan sikap keselamatan perawat. Jenis kelamin, posisi, jenjang karir, pendidikan, usia serta pengalaman kerja secara signifikan berpengaruh pada sikap keselamatan (P<0,05). Perbaikan dan peningkatan sikap keselamatan perawat dapat dievaluasi dan diperbaiki dengan mempertimbangkan karaktersitik perawat agar upaya upaya tersebut dapat tepat sasaran dan sesuai dengan kebutuhan.
OPTICAL WAVEGUIDE BERSTRUKTUR GABUNGAN ANTARA LOOP DAN DIRECTIONAL BERBASIS MACH ZEHNDER INTERFEROMETER

Optical Waveguide berstruktur gabungan antara Loop dan Directional berbasis Mach Zehnder Interferometer (MZI) telah dianalisa dengan menggunakan metode beda hingga (Finite Difference). Dimensi total dari divais ini adalah 24x2400 mikron dengan lebar masing-masing waveguide sebesar 6 mikron terdiri dari 2 kanal input dan 2 kanal output. Dua kanal input tersebut masing-masing terdiri dari input signal dan input kontrol yang terpisah sejauh parameter gap sekitar 0-20 mikron. Hasil analisa propagasi gelombang LaserDiode (LD) menunjukkan bahwa prinsip MZI dapat diterapkan dalam divais ini dengan sempurna, yaitu propagasi signal LD dalam struktur salah satu tangkai loop dapat diganggu fase gelombangnya oleh propagasi LD dalam pandu gelombang control pada jarak gap tertentu. Perbedaaan fase gelombang dalam struktur loop mengakibatkan superposisi gelombang yang saling meniadakan dibagian kanal output. Sehingga divais ini cocok untuk diaplikasikan sebagai gerbang logika optik dalam sistem Opto-Electronic Integrated Circuit (OEIC).
SNP-bin linkage analysis and genome-wide association study of plant height in soybean

ABSTRACT As the major source of edible protein and oil, the global demand for soybean (Glycine max (L.) Merr. ) is increasing. Plant height is closely related to yield; therefore, understanding the genetic basis of plant height will help to improve soybean plant type and increase seed yield. In this study, quantitative trait loci (QTLs) and nucleotides (QTNs) for soybean plant height were detected by linkage analysis and association analysis. A high-density map containing 2225 bin markers was constructed by using 108 342 SNPs of a recombinant inbred line population (named RIL3613) of 120 lines for linkage analysis. In total, 39 QTLs were detected, including 16 QTLs that were repeatedly detected in multiple environments. Association analysis was performed by using 63 306 SNPs from a germplasm population of 455 natural soybean accessions. In total, 62 QTNs were detected, and 26 QTNs were repeatedly detected by multiple methods. Fourteen QTNs were distributed in the intervals of six multiple-environment QTLs by comparing the results of association analysis and linkage analysis. With pathway analysis, six candidate genes were identified as being associated with plant height. These results contribute to analysis of the genetic basis of plant height and will promote marker-assisted selection for breeding ideal plant shape.
Development of a Real-Time Stringlines Tool to Visualize Subway Operations and Manage Service at New York City Transit

In 2013, with real-time train arrival data becoming widely available through its general transit feed specification real-time (GTFS-RT) feed, New York City Transit (NYCT) recognized the potential for new service management tools capable of on-the-fly performance visualization and reporting. This paper describes the process taken by NYCT to develop and evaluate a transit analysis tool that uses information from automatic train supervision countdown clocks, transmitted as GTFS-RT data, to visualize train spacing, movement, and related parameters. The main part of this tool is a new web application that uses stringline (time–distance) charts for monitoring operations in the system as they happen. Operational problems (e.g., delays, train bunching, or gaps in service) can be identified more easily on stringline charts than on the traditional model board display to help managers and operating personnel deliver continuous service performance improvements. The application was built in-house with the use of existing data resources (the GTFS-RT feed of predicted train arrivals) and open-source tools. In-house development minimized cost and allowed for maximum flexibility to add features in the future. The development team successfully employed a methodology of iterative development to incrementally review, add features, and test the application without having to go through very long design and requirements cycles. As more transit agencies release GTFS-RT data to the public, they may see opportunities to take a similar approach to develop new tools for internal use quickly and with little additional cost.
Systemic Integrated Unmanned Aerial System

Systemic integrated Unmanned Aerial System (UAS), is the process of gathering the subsystems into one fulfilled system. This integration is done in order to improve the system performance, reducing operational costs, and improving the time response of the system. Normally, such systems are integrated using different techniques such as communication processes, and computer networking. In this paper, a new integrated system is implemented by linking functionally computing systems and software applications together in one powerful system.
The role of organisational commitment in knowledge sharing amongst academics: an insight into the critical perspectives for higher education

Purpose This study investigates the interrelationships between the components of perceived organisational commitment (affective, continuance and normative commitment) and knowledge sharing (KS) intentions, attitudes and contributions amongst academics. It was hypothesised that organisational commitment has a positive mediating role in KS behaviours.Design/methodology/approach To reveal the interrelationships between the components of perceived organisational commitment and KS, a correlational research design through path analysis was employed.Findings There were significant correlations between organisational commitment components and KS. Participants with higher perceived affective commitment had higher levels of KS intentions. Similarly, participants with higher perceived normative commitment had higher levels of attitudes towards KS. However, higher levels of perceived continuance commitment were related to lower levels of expected contributions to KS.Research limitations/implications The study was limited to participants working for a state university in Turkey. In Turkish state universities, continuance and normative commitment may be regarded differently due to unique working conditions.Practical implications The results revealed that commitment to an organisation facilitates KS in higher education institutions, which suggests that administrators and practitioners should increase organisational commitment to create a working environment with more KS.Originality/value Although organisational commitment and KS have been investigated in educational settings previously, this study contributes to the literature by discovering the specific interrelationships between these factors, offering a more complete picture that could be beneficial for practice.
In Situ Characterization of the Reaction-Diffusion Behavior during the Gradient Interphase Formation of Polyetherimide with a High-Temperature Epoxy System

This study presents two novel methods for in situ characterization of the reaction-diffusion process during the co-curing of a polyetherimide thermoplastic interlayer with an epoxy-amine thermoset. The first method was based on hot stage experiments using a computer vision point tracker algorithm to detect and trace diffusion fronts, and the second method used space- and time-resolved Raman spectroscopy. Both approaches provided essential information, e.g., type of transport phenomena and diffusion rate. They can also be combined and serve to elucidate phenomena occurring during diffusion up to phase separation of the gradient interphase between the epoxy system and the thermoplastic. Accordingly, it was possible to distinguish reaction-diffusion mechanisms, describe the diffusivity of the present system and evaluate the usability of the above-mentioned methods.
Feasibility and Safety of Laparoscopic Portal Vein Ligation Prior to Major Hepatectomy for Hepatocellular Carcinoma

Background: Patients with hepatocellular carcinoma (HCC) demonstrated to have an inadequate future liver remnant (FLR) on preoperative volumetric assessment are potential candidates for laparoscopic portal vein ligation (LPVL). Previous studies have reported that for patients with hepatic malignancies, laparoscopic portal vein ligation (LPVL) is efficient in increasing FLR, which, however, has not been solely reported in HCC. The purpose of this study was to evaluate the safety, feasibility and efficiency of LPVL prior to major hepatectomy for patients with HCC. Methods: Clinical information of HCC patients who had undergone laparoscopic portal vein ligation (LPVL) at our center was retrospectively reviewed and documented. Demographic, radiographic, clinical and volumetric details (both before and after LPVL) were retrieved to evaluate the feasibility and safety of LPVL prior to major hepatectomy for HCC. Results: Between April 2020 and December 2021, there were a total of 10 HCC patients undergoing LPVL as a preparation for subsequent major hepatectomy at our center. The mean age of these 10 patients was 61.30±8.83 years old. Of these 10 patients, 9 were male and only 1 was female. 9 patients underwent laparoscopic ligation of the right portal vein and one the left portal vein. All the patients, left or right portal veins were ligated by clips. After LPVL, the mean volume increased from 433.16±103.64 ml to 550.62±123.19 ml (P＜0.001）. All the 10 patients had adequate hypertrophy of FLR and subsequent major hepatectomy was performed as scheduled. No LPVL-associated complications were recorded. Conclusion: LPVL is both feasible and could be safely performed. For carefully selected patients, LPVL could be considered as a safe and feasible alternative to portal vein embolization (PVE) given the rather low complication rate and high efficiency of LPVL.