Miracle-dz/UniFAR-FTUs huggingface dataset:
Perception of reverse mentoring by the seniors in Moroccan organizations: An exploratory study

Nowadays we are living through the biggest technological revolution in history, at all levels. This technology has been the key to the success of the organization, and allows this latter to stand out from the competition. This being said, the organization needs to seek technological competences and retain it inside the company. Taking into consideration the generational diversity existing inside the organization (old and young employees), it is worth exploring the transfer of knowledge from the junior to senior, since the youngest generations (Y and Z gens) are the best manipulators of the technology. This kind of knowledge transfer is called “The reverse mentoring”, a trendy HR management tool, that has been defined according to Harvey, McIntyre, Heames, and Moeller (2009) as a valuable instrument for senior employees to learn new technical knowledge, understand new trends and approaches, to realize the generational differences and to reduce their assumptions and negative stereotypes about younger generations. Murphy (2012) states that “reverse mentoring turns traditional mentoring formula on its head”. This concept can be defined as a professional development and social exchange tool which includes knowledge and experience sharing. The objective of this paper is to study the perception of reverse tutoring -as an intergenerational knowledge transfer toolby the seniors who will be for the first time in the role of the mentee. Through this study, we will also explore the acceptance or not of this new practise by the seniors. The adopted methodology is a qualitative study.
AIU-Net: An Efficient Deep Convolutional Neural Network for Brain Tumor Segmentation

Automatic and accurate segmentation of brain tumors plays an important role in the diagnosis and treatment of brain tumors. In order to improve the accuracy of brain tumor segmentation, an improved multimodal MRI brain tumor segmentation algorithm based on U-net is proposed in this paper. In the original U-net, the contracting path uses the pooling layer to reduce the resolution of the feature image and increase the receptive field. In the expanding path, the up sampling is used to restore the size of the feature image. In this process, some details of the image will be lost, leading to low segmentation accuracy. This paper proposes an improved convolutional neural network named AIU-net (Atrous-Inception U-net). In the encoder of U-net, A-inception (Atrous-inception) module is introduced to replace the original convolution block. The A-inception module is an inception structure with atrous convolution, which increases the depth and width of the network and can expand the receptive field without adding additional parameters. In order to capture the multiscale features, the atrous spatial pyramid pooling module (ASPP) is introduced. The experimental results on the BraTS (the multimodal brain tumor segmentation challenge) dataset show that the dice score obtained by this method is 0.93 for the enhancing tumor region, 0.86 for the whole tumor region, and 0.92 for the tumor core region, and the segmentation accuracy is improved.
Improving Blood Pressure Control Using Digital Communication Methods in Serbia

Background: The purpose of this study was to compare home and office BP in the adjustment of antihypertensive treatment. Methods: This study was an open, prospective, noninterventional, multicenter clinical trial that occurred between July 2019 and February 2020, in 34 cities in the territory of the Republic of Serbia, which monitored 1581 participants for 6 months. Depending on the used blood pressure monitoring method used, all patients were divided into control (office BP monitoring) and experimental (home BP telemonitoring) groups. We collected anamnestic data and data about systolic blood pressure (SP), in mmHg, diastolic blood pressure (DP), in mmHg, and heart rate (HR), in beats/minute, from all patients. Results: SP values were significantly different at baseline, and at the second, third, and fourth visits between the two tested groups. Home and office BP decreased significantly (p < 0.000) during the 6-month follow-up. We observed a statistically significant influence of the presence of diabetes mellitus and dyslipidemia on the dynamics of differences between SP monitoring values. Conclusions: Our study suggests that novel technologies in BP monitoring can be excellent alternatives for BP assessment in hypertensive patients with other cardiovascular risk factors such as diabetes and dyslipidemia.
Actuarial applications of multivariate phase-type distributions : model calibration and credibility

28 2.
Statistics of normal mode amplitudes in a random ocean

Acoustic waves in a random ocean have been studied by means of coupled mode equations, a system of stochastic ordinary differential equations for the acoustic normal mode amplitudes as a function of range. The random coupling coefficients represent scattering from internal wave normal modes. Deterministic master equations, which predict the average power in each mode as a function of range, can be derived from the coupled mode equations by using certain approximations. Monte Carlo simulations, numerically solving many realizations of the coupled mode equations, have been carried out in order to establish the validity of the master equations as a function of range and acoustic frequency. In addition, fluctuations of the power about the average value are predicted by yet another system of equations, but whose coefficients are linear combinations of those appearing in the master equations. The Monte Carlo results also establish the region of validity of these fluctuation predictions. [Work supported by ONR. ]
MANUAL FOR THE GALAXY N-BODY SIMULATION CODE

2 Overview of the simulation code GALAXY 8 2.1 Code structure . 8 2.2 Computing the gravitational field of the particles . 8 2.2.1 Grid methods . 8 2.2.2 Field methods . 9 2.2.3 Direct methods . 9 2.2.4 Hybrid or 2-grid methods . 9 2.3 System of units . 10 2.4 Scaling the simulation . 10 2.5 Files . 11 2.6 Memory organization . 11
Treatment of Osteoporosis: Are Physicians Missing an Opportunity?*†

Background: Medical treatment of women with established osteoporosis may decrease the incidence of future fractures. Postmenopausal women who have sustained a distal radial fracture have decreased bone-mineral density and nearly twice the risk of a future hip fracture. The purpose of this study was to evaluate the adequacy of diagnosis and treatment of osteoporosis in postmenopausal women following an acute fracture of the distal part of the radius. Methods: A retrospective cohort study was performed with use of a claims database that includes more than three million patients, from thirty states, enrolled in multiple health plans. All women, fifty-five years of age or older, who sustained a distal radial fracture between July 1, 1994, and June 30, 1997, were identified in the database. Only patients with at least six months of continuous and complete medical and pharmaceutical health-care coverage from the date of the fracture were enrolled, to ensure that all health-care claims would be captured in the database. This cohort of patients was then evaluated to determine the proportion who had undergone either a diagnostic bone-density scan or treatment with any recommended medication for established osteoporosis (estrogen, a bisphosphonate, or calcitonin) within six months following the fracture. Results: A search of the database identified 1162 women, fifty-five years of age or older, who had a distal radial fracture. Of these 1162 patients, thirty-three (2.8 percent) underwent a bone-density scan and 266 (22.9 percent) were treated with at least one of the medications approved for treatment of established osteoporosis. Twenty women had both a bone-density scan and drug treatment. Therefore, only 279 (24.0 percent) of the 1162 women who sustained a distal radial fracture underwent either diagnostic evaluation or treatment of osteoporosis. There was a significant decrease in the rate of treatment of osteoporosis with increasing patient age at the time of the fracture (p < 0.0001). Conclusions: Current physician practice may be inadequate for the diagnosis and treatment of osteoporosis in postmenopausal women who have sustained a distal radial fracture.
The heat-shock response.

PERSPECTIVES AND SUMMARY . 1151 CHARACTERIZATION OF THE RESPONSE 1153 Comparison: Different Organisms and Stages of Development. ll53 The Proteins Induced by Heat . 1155 RNAs Induced by Heat 1167 OTHER INDUCTIONS OF HSPs 1168 Developmental Inductions . 1168 Other Inducers 1 1 69 Is There a Common Mechanism? 1170 GENOME ORGANIZATION 1172 REGULATION OF THE RESPONSE 1173 Transcription 1173 Translation . 1177 RNA Processing 1178 TOLERANCE TO HEAT AND OTHER FORMS OF STRESS . 1179 Heat-Induced Lethality and Thermotolerance . 1179 Phenocopies 1182 CONCLUDING REMARKS 1184
Community Social Capital and Depressive Symptoms Among Older People in Japan: A Multilevel Longitudinal Study

Background This study aimed to examine the contextual effects of community-level social capital on the onset of depressive symptoms using a longitudinal study design. Methods We used questionnaire data from the 2010 and 2013 waves of the Japan Gerontological Evaluation Study that included 14,465 men and 14,600 women aged over 65 years from 295 communities. We also used data of a three-wave panel (2006–2010–2013) to test the robustness of the findings (n = 7,424). Using sex-stratified multilevel logistic regression, we investigated the lagged associations between three scales of baseline community social capital and the development of depressive symptoms. Results Community civic participation was inversely associated with the onset of depressive symptoms (men: adjusted odds ratio [AOR] 0.93; 95% confidence interval [CI], 0.88–0.99 and women: AOR 0.94; 95% CI, 0.88–0.997 per 1 standard deviation unit change in the score), while no such association was found in relation to the other two scales on social cohesion and reciprocity. This association was attenuated by the adjustment of individual responses to the civic participation component. Individual-level scores corresponding to all three community social capital components were significantly associated with lower risks for depressive symptoms. The results using the three-wave data set showed statistically less clear but similar associations. Conclusions Promoting environment and services enhancing to community group participation might help mitigate the impact of late-life depression in an aging society.
FORMULATION, CHARACTERIZATION AND IN VIVO APPLICATION OF ORAL INSULIN NANOTECHNOLOGY USING DIFFERENT BIODEGRADABLE POLYMERS: ADVANCED DRUG DELIVERY SYSTEM.

Mohamed Kassem 1 , Amir Ali 2 , Mona El-Assal 3 and * Ali El-badrawy 2 . 1. Department of Pharmaceutics, Faculty of Pharmacy, Cairo University, 11562, Cairo, Egypt. 2. Military medical academy, 11774, Cairo, Egypt. 3. Department of Pharmaceutics and pharmaceutical technology, Faculty of Pharmaceutical Sciences and pharmaceutical industries, FUE University, 11835, Cairo, Egypt. Manuscript Info Abstract . Manuscript History
SOLDER JOINT RELIABILITY ON MIXED SAC-BISN BALL GRID ARRAY SOLDER JOINTS FORMED WITH RESIN REINFORCED BI-SN METALLURGY SOLDER PASTES

Due to the decreasing size of consumer electronic products such as smart phones, tablets, and personal computers, ultrathin flip chip ball grid array (FCBGA) packages are needed to meet the demand of lower z-heights for slimmer form factors. However, packages used in consumer electronics are commonly assembled on printed circuit boards (PCB) with lead-free SnAgCu (SAC) solder paste at peak reflow temperatures in the 240C to 260C range. Assembly challenges are observed at these peak reflow temperatures due to dynamic warpage of the component substrates of ultra-thin FCBGAs, as well as the PCB. The Bi-Sn low temperature solder metallurgical system has been proposed as an alternative to the SAC metallurgical system to overcome these package substrate and PCB warpage induced assembly challenges. Besides improving solder joint yields on ultra-thin FCBGAs, the lower melting point of this Bi-Sn metallurgy also enables manufacturing cost savings and environmental benefits. However, based on previous literature studies, the presence of Bi in Sn-based low temperature solder has exhibited solder joint embrittlement and thereby decreased the mechanical shock resistance of such solder joints. In order to strengthen the solder joint, low temperture solder pastes have been developed containing resin, which by flowing around the solder joint and curing during the reflow process it provides polymeric encapsulation reinforcement at the solder joint level. In a previous study [16], this type of low temperature joint reinforced paste (JRP) had shown improved mechanical shock resistance on mixed BiSn+SnAgCu FCBGA solder joints when compared to those without the polymeric encapsulation. However, the effect of thermal fatigue on the resin reinfroced BiSn+SnAgCu BGA solder joint when subjected to thermal cycling needed to be better understood. In this paper, the investigation centered on both the mechanical shock and the thermal cycling performance of the mixed BiSnAg (BSA)+SAC solder joints assembled with JRP pastes on a Flip Chip Molded Package BGA (FCMB) and compared the data to those assembled with SAC305 paste. Reliability failure rate characterized with Weibull distributions, failure modes and locations within the solder joint stack-up were determined. Results indicated that the mixed SAC+BiSn solder joints with polymeric reinforcement when using two different JRPs were less shock resistant than the SAC solder joints for both JRPs. More development is therfore necessary with JRPs to enable low temperature Bi-Sn solder joints to become comparable with un-reinforced SAC BGA solder joints under mechanical shock. There was significant improvement in the thermal cycling performance for mixed SAC+BiSn solder joints formed using one of the JRPs, but this improvement was for the solder joints located at the package corners only. The level of encapsulation of the solder joints by the reinforcing resin was inconsistent across the FCMB array and this could have caused this inconsistent temperature cycling resistance.
Alcoholic Korsakoff's Syndrome: An Update

In 188 1, Carl Wernicke described in three patients (two male alcoholics and one woman with sulfuric acid poisoning) a neurologic syndrome that included ataxia, optic abnormalities, and a confusional state. Postmortem examination of these three patients showed small punctate hemorrhages symmetrically located in the gray matter around the third and fourth ventricles of the brains. Wernicke characterized this disorder, which now bears his name, as an acute inflammatory disease of the oculomotor nuclei and noted that the symptoms were progressive and led to death in approximately 2 weeks. Six years following the publication of Wernicke's paper, S.S. Korsakoff published the first of a series of reports in which he detailed the amnesic and confabulatory symptoms that often accompanied disorders involving polyneuropathy. Although long-term alcoholism often preceded these mental changes, Korsakoff noted that the symptoms also followed a number of other conditions, such as persistent vomiting, typhoid fever, and intestinal obstruction. On the basis of his observations, he concluded that the presence of a substance toxic to the peripheral and central nervous systems must have been the common denominator in his reported cases. Although neither Wernicke nor Korsakoff could be specific with regard to etiology, and both seemed unaware that their two syndromes often occurred sequentially in the same patients, their clinical descriptions of their patients' symptomatology were accurate and represented important initial steps in the identification and understanding of the Wernicke-Korsakoff syndrome. The major symptoms of the Wernicke stage include a global confusional state, ophthalmoplegia, nystagmus, ataxia, and polyneuropathy (pain, loss of sensation, weakness) of the legs and arms. ' Of these neurologic symptoms, the global confusional state is perhaps most germane to our interests. The patient is disoriented with regard to time and place, is unable to recognize familiar people, i> apathetic, inattentive, and, most significant, is unable to maintain a coherent conversation. If a patient with Wernicke's encephalopathy is not treated with large doses of thiamine, he is in danger of having fatal midbrain hemorrhages. If. however, the patient does receive proper vitamin therapy, the neurologic symptoms will improve markedly. In most cases, the ocular problems will almost disappear, the ataxia and peripheral neuropathies will improve, and the confusional state will clear. That is, after 2 or 3 weeks of thiamine treatment, the patient will realize that he is in a hospital, recognize his wife and children, and be able to maintain an intelligible conversation with his physician. At this point, that patient has passed the acute Wernicke phase and has entered the chronic Korsakoff stage. Few Wernicke patients (about 25%) show a complete recovery to their premorbid intellectual state. '
Association between Adolescent Substance Use and Weapon Carrying: Analysis of 2013 YRBS

Purpose: Substance use and weapon carrying among adolescents is a growing concern. The objective of this study is to investigate the association between adolescent substance use and weapon carrying using the 2013 Youth Risk Behavior Survey (YRBS). Methods: Analyses were conducted using the 2013 YRBS, a nationally representative dataset sampling public and private high school students throughout the United States (US). Data from a total of 148,282 US adolescents were used in the present study. Results: Two outcomes were assessed: weapon carrying within the past 30 days and weapon carrying on school property within the past 30 days. Among adolescents who carried a weapon, 77.3% were male, 62.7% were white, 28.5%% were in 9 th grade, 33.8% used a tobacco product and 57.4% drank alcohol within the past 30 days, while 22.8% used a Schedule 1 drug and 14.0% used a Schedule 2 drug during their lifetime. Among adolescents who carried a weapon on school property, 74.4% were male, 55.1% were white, 26.5% were in 11 th grade, 40.1% used a tobacco product and 61.9% drank alcohol within the past 30 days, while 32.1% used a Schedule 1 drug and 26.9% used a Schedule 2 drug during their lifetime. For the multivariable model predicting adolescent weapon carrying, tobacco use (adjusted odds ratio (AOR) = 2.31,80) were significantly associated with increased risk of carrying a weapon, adjusting for all covariates in the model simultaneously. For the multivariable model 2 predicting adolescent weapon carrying on school property, tobacco use were significantly associated with increased risk of carrying a weapon on school property, adjusting for all covariates in the model. Raw counts and weighted frequencies are reported. Conclusions: Statistically significant associations between adolescent substance use and weapon carrying were found, suggesting that adolescent substance use is associated with increased weapon carrying behavior, both off and on school property. Future weapon carrying prevention efforts should target not only adolescents who are high risk for weapon carrying, but also those who are at risk for misusing substances.
Who Are The Tourists?

Tourism is the subject of much research and evaluation at the national or international level. however, tourism remains under-theoretical and defining tourism has long been a challenge for those studying this field. Whether it is a question of quantifying flows, measuring the importance of recurrent and emerging practices, or identifying motivations for choosing destinations and activities, one of the priorities is to be able to accurately identify the subject of study. Purpose of the study are to review (i) who is the author of these socalled "tourist" trips and stays? , and (ii) who can be classified as a tourist? method is based on on the review of some literatures related to the topic. The results show that contextualized and recalled the definitions of tourists based on the recommendations made since IRTS 2008 by the supranational organization for the promotion of tourism on a global scale
Photoinhibition of Photosynthesis in Nature

CONTENTS INTRODUCTION . 633 MECHANISMS . 636 Photosystem Il Inacti vaJion, Damage and Recovery: The DI Story 637 A voidance of PSll Damage: The Xanthophyll Cycle Story . 640 Damage rmd A voidance: A Blurring of the Division . 643 PHOTOINHIBITION IN THE FIELD AND OPEN OCEAN . 644 Terrestrial VegetaJion . 644 Phytoplankton 646 SIGNIFICANCE TO PRODUCTION: A MODELING APPROACH 648 OBSERVED CHANGES IN PRODUCTION . 653 PHOTO INHIBITION AND PLANT DISTRIBUTIONS . 654 CONCLUSIONS . 655
QTL mapping of virulence traits in Zymoseptoria tritici

iii Zusammenfassung v Introduction 1 1 Measuring quantitative virulence in the wheat pathogen Zymoseptoria tritici using high throughput automated image analysis 7 1.1 Abstract . 7 1.2 Introduction . 7 1.3 Materials and Methods . 9 1.3. 1 Inoculation assay . 9 1.3. 2 Automated assessment of quantitative virulence based on digitized images . 9 1.3. 3 Visual assessment of quantitative virulence using projected images . 10 1.3. 4 Data analyses . 11 1.4 Results . 11 1.4. 1 Measurements of quantitative virulence using automated image analysis . 11 1.4. 2 Comparison of results from automated image analysis and visual assessment . 14 1.5 Discussion . 14 1.6 Acknowledgements . 18 2 An improved method for measuring quantitative resistance to the wheat pathogen Zymoseptoria tritici using high throughput automated image analysis 19 2.1 Abstract . 19 2.2 Introduction . 19 2.3 Materials and Methods . 21 2.3. 1 Validation using naturally infected leaf samples from field experiments . 22 2.3. 2 Image Analysis . 23 2.3. 3 Data analyses . 23 2.4 Results . 24 2.5 Discussion . 26 2.6 Acknowledgments . 31
Bile Acid-Stimulated Expression of the Farnesoid X Receptor Enhances the Immune Response in Barrett Esophagus

OBJECTIVES:Barrett's esophagus (BE) is a premalignant condition of the esophagus. It is a consequence of mucosal injury from chronic gastroesophageal reflux in which bile acids are an important toxic component. The farnesoid X receptor (FXR) is a nuclear receptor involved in the regulation of bile acid synthesis, transport, and absorption. FXR activation is also involved in the induction of the innate immune response. This suggests that FXR is involved in the pathogenesis and the inflammation seen in BE.METHODS:mRNA levels of FXR and the FXR-regulated genes, ileal bile acid-binding protein (IBABP), small heterodimer partner (SHP), and chemokines interleukin (IL)-8 and macrophage inflammatory protein 3α (MIP3α), were determined by real time-polymerase chain reaction (RT-PCR). Protein expression was determined by immunohistochemistry.RESULTS:FXR was not expressed in squamous epithelium of healthy subjects (N = 7), but was present in both squamous and columnar epithelium of BE patients. Compared to the squamous epithelium of BE patients, their columnar epithelium displayed a 2.3-fold (P= 0.02) increase in FXR mRNA. Also, IBABP (2.2-fold; P= 0.0029), SHP (2.7-fold; P= 0.007), IL-8 (1.5-fold; P= 0.04), and MIP3α (1.7-fold; P= 0.019) transcription levels were increased. Exposure of esophageal cell line TE7 to deoxycholic acid (DCA) resulted in a similar induction. The induction was abolished by the FXR antagonist guggulsterone.CONCLUSIONS:Expression levels of the bile acid receptor FXR, the bile acid metabolism genes IBABP and SHP, and the chemokines IL-8 and MIP3α are increased in Barrett's epithelium. The in vitro induction of FXR by DCA suggests that bile acids can actively induce the inflammatory response in BE by recruiting immune cells.