Miracle-dz/UniFAR-FTUs huggingface dataset:
Periphytic Algae and Cyanobacteria from the Rio Doce Basin Respond Differently to Metals and Salinity, Showing Different Potential for Bioremediation

We have studied the isolated and combined effects of metals (Fe and Mn) and NaCl the on growth, physiology, and metal-uptake capacity of two photosynthetic periphytic species—Synechococcus elongatus (Cyanobacteria) and Chlorococcum infusionum (Chlorophyta)—isolated from an impacted area of the Rio Doce River (Brazil) after the Fundão dam collapse. The effective concentrations found to reduce 10 and 50% growth were 15.2 and 31.6 mg Fe L−1, and 2.5 and 7.9 mg Mn L−1 for S. elongatus and 53.9 and 61.6 mg Fe L−1, and 53.2 and 60.9 mg Mn L−1 for C. infusionum. Although the metal toxicity was related to oxidative stress, both species showed activation of antioxidant systems under phytotoxic concentrations of Fe and Mn. By binding large concentrations of metals on its cell surface and thus avoiding their entrance into the cells, C. infusionum presents greater resistance to Fe and Mn than S. elongatus. Under environmental realistic concentrations of Fe and Mn in river water from the Rio Doce Basin, S. elongatus and C. infusionum showed a metal removal efficiency of 42 and 65% and 53 and 79%, respectively after 96 h. These species were insensitive to increased NaCl concentrations which, in addition, did not disrupt the metal removal capacity of the species. Due to their salt and metal tolerance, S. elongatus and C. infusionum can be used for the remediation of waters contaminated with Fe and Mn.
Implementation and Evaluation of Scalability Techniques in the ECO Model

Event-based communication is appropriate for many application domains, ranging from small, centralised applications such as GUIs to large, distributed applications such as telecommunications, network monitoring and virtual world support systems. Consequently, many di erent event models have been put forward, some designed for small-scale systems and others for large-scale systems. One such model is the eco model which was designed to support virtual world applications in the Moonlight project. The eco model was designed to be scalable by including ltering capabilities that were intended to decrease network tra c in a distributed implementation. There have been two previous implementations of the eco model, and one characteristic of both was that all code was linked into the application at compile time, regardless of whether it was used at runtime or not. This resulted in executables which were larger than strictly necessary, and consequently lower scalability for applications hosting many objects, most of which were used only on a few nodes. A better approach could be to link code on demand at runtime with the intention of decreasing the application footprint. This thesis describes the design and implementation of a distributed version of the eco model and the evaluation of lters and dynamic linking as means to achieve increased scalability. The evaluation is empirical and real data gathered from an actual event-based system is used. In addition to the design and evaluation chapters, a detailed review of four event models, including the eco model, is provided, with particular emphasis on ltering and dynamic linking.
Exploring Aesthetic Visualization for Promoting Consumer Energy Conservation

Tree without Berries As a variation to the berry tree design, we also included a tree visualization without the berries (Figure 5-5) in our study for the purpose of finding out whether the explicit representation of positive actions would make a difference in engaging children and encouraging more energy conservation behaviour. The data mapping to the tree is identical to the one discussed above except positive actions are not displayed. In other words, the berries are omitted.
Asset Management Inventory and Data Collection

An efficient and accurate inventory of a state highway agency’s assets, along with the means to assess the condition of those assets and model their performance, is critical to enabling an agency to make informed investment decisions in a Transportation Asset Management (TAM) environment. Today, new technologies provide fast and improved ways to gather, process, and analyze data. The key is to identify and gather the most useful, reliable, cost-effective information and use it to make informed decisions for asset management. Four key infrastructure areas have been identified as primary asset components; pavements, bridges, geotechnical features, and roadside appurtenances. Each area contains multiple categories and data elements important for sound decision making. Although some similarities exist in these four primary categories, the nature of data collection may differ, depending on the asset type. The sheer number of data elements and the length of asset networks for pavements and roadside appurtenances render the automated highway speed data collection method a necessity rather than a luxury. However, the discrete nature of bridges and geotechnical features make the automated mobile data collection method on a network level unfeasible with today’s technology. Important issues in the collection process include precision, subjectivity and variability of the process itself, as well as speed, safety of the survey crew, proximity of the public, cost, etc. Although previous research has attempted to address these issues and determine the most appropriate method(s), the question remains as to which roadway data collection system is best for state highway agencies given real world constraints. This research set up a “sealed envelope” experiment wherein the identification, location, description, and quality of the asset data elements are known only to NCSU researchers. Vendors are informed of only the data necessary to perform their evaluation. To support this effort a 95-mile test course near Raleigh, North Carolina was identified, which contained a sampling of pavement, roadside, geotechnical and bridge elements. This document reports on the findings from the study.
Soutenir la persévérance des étudiants (sur campus et à distance) dans leur première session d’études universitaires : constats de recherche et recommandations

Quelles sont les mesures mises en place pour contrer le phénomène d’abandon des études universitaires? Comment des outils d’aide et de soutien à la persévérance aux études, accessibles en ligne, sont-ils utilisés par des étudiants nouvellement inscrits en première session d’études universitaires? Une étude auprès de 216 étudiants (sur campus et à distance) dans trois universités québécoises montre qu’ils ont des difficultés sur le plan des compétences et connaissances préalables, des stratégies d’apprentissage et d’autorégulation ainsi que de la lecture de l’anglais et du français, et que les mesures de soutien mises en ligne (S@MI-Persévérance) ont été utilisées pour résoudre ces difficultés . Abstract
The value of open data government: a quality assessment approach

Data quality involves a set of characteristics, values, and expressions that are built iteratively. Open government data (OGD) shares the qualities of Big Data regarding volume, speed, accuracy, and value, and the purpose of achieving stakeholders’ reuse stands out. This study uses a bibliographic review to identify the relationships among big data, open data, data quality, and value. We conclude that OGD, a recent trend, encourages collaboration and citizen participation and enables reusing data to pursue public and private innovation. Ensuring data quality makes it possible to obtain value from its reuse and generate Economic Value, Commercial Value, Social Value, and Public Value. Consumers require a solid basis of trust before using public information, which requires a data quality assurance process that strengthens and intensifies the inherent value of the data and activates its potential in different contexts.
Multi-lingual Sentiment Analysis of Financial News Streams

Department of Computing, University of Surrey Guildford, Surrey, GU2 7XH, United Kingdom E-mail: y.almas@surrey.ac. uk Encouraged by the feasibility demonstration that a relatively low-cost grid environment can speed up the processing of continuous text streams of financial news in English, we have attempted to replicate our methods for automatic sentiment analysis in two major languages of the world – Arabic and Chinese. We show that our local grammar approach, developed on an archive of English (Indo-European language) texts, works equally on the typologically different Chinese (Sino-Asiatic) and Arabic (Semitic) languages. Grid Technology for Financial Modeling and Simulation February 3/4, 2006 – Palermo, (Italy)
Integrative Analyses Reveal Tstd1 as a Potential Modulator of HDL Cholesterol and Mitochondrial Function in Mice

High-density lipoprotein (HDL) cholesterol levels are closely associated with human health and diseases. To identify genes modulating plasma HDL levels, we integrated HDL measurements and multi-omics data collected from diverse mouse cohorts and combined a list of systems genetics methods, including quantitative trait loci (QTL) mapping analysis, mediation analysis, transcriptome-wide association analysis (TWAS), and correlation analysis. We confirmed a significant and conserved QTL for plasma HDL on chromosome 1 and identified that Tstd1 liver transcript correlates with plasma HDL in several independent mouse cohorts, suggesting Tstd1 may be a potential modulator of plasma HDL levels. Correlation analysis using over 70 transcriptomics datasets in humans and mice revealed consistent correlations between Tstd1 and genes known to be involved in cholesterol and HDL regulation. Consistent with strong enrichment in gene sets related to cholesterol and lipoproteins in the liver, mouse strains with high Tstd1 exhibited higher plasma levels of HDL, total cholesterol and other lipid markers. GeneBridge using large-scale expression datasets identified conserved and positive associations between TSTD1/Tstd1 and mitochondrial pathways, as well as cholesterol and lipid pathways in human, mouse and rat. In summary, we identified Tstd1 as a new modulator of plasma HDL and mitochondrial function through integrative systems analyses, and proposed a new mechanism of HDL modulation and a potential therapeutic target for relevant diseases. This study highlights the value of such integrative approaches in revealing molecular mechanisms of complex traits or diseases.
Analytical gradients for projection-based wavefunction-in-DFT embedding

Projection-based embedding provides a simple, robust, and accurate approach for describing a small part of a chemical system at the level of a correlated wavefunction (WF) method, while the remainder of the system is described at the level of density functional theory (DFT). Here, we present the derivation, implementation, and numerical demonstration of analytical nuclear gradients for projection-based wavefunction-in-density functional theory (WF-in-DFT) embedding. The gradients are formulated in the Lagrangian framework to enforce orthogonality, localization, and Brillouin constraints on the molecular orbitals. An important aspect of the gradient theory is that WF contributions to the total WF-in-DFT gradient can be simply evaluated using existing WF gradient implementations without modification. Another simplifying aspect is that Kohn-Sham (KS) DFT contributions to the projection-based embedding gradient do not require knowledge of the WF calculation beyond the relaxed WF density. Projection-based WF-in-DFT embedding gradients are thus easily generalized to any combination of WF and KS-DFT methods. We provide a numerical demonstration of the method for several applications, including a calculation of a minimum energy pathway for a hydride transfer in a cobalt-based molecular catalyst using the nudged-elastic-band method at the coupled-cluster single double-in-DFT level of theory, which reveals large differences from the transition state geometry predicted using DFT.
Modelling and analysis of interconnects for deep submicron systems-on-chip.

The last few decades have been a very exciting period in thedevelopment of micro-electronics and brought us to the brink ofimplementing entire systems on a single chip, on a hithertounimagined scale. However an unforeseen challenge has croppedup in the form of managing wires, which have become the mainbottleneck in performance, masking the blinding speed of activedevices. A major problem is that increasingly complicatedeffects need to be modelled, but the computational complexityof any proposed model needs to be low enough to allow manyiterations in a design cycle.This thesis addresses the issue of closed form modelling ofthe response of coupled interconnect systems. Following astrict mathematical approach, second order models for thetransfer functions of coupled RC trees based on the first andsecond moments of the impulse response are developed. The2-pole-1-zero transfer function that is the best possible fromthe available information is obtained for the signal path fromeach driver to the output in multiple aggressor systems. Thisallows the complete response to be estimated accurately bysumming up the individual waveforms. The model represents theminimum complexity for a 2-pole-1-zero estimate, for this classof circuits.Also proposed are new techniques for the optimisation ofwires in on-chip buses. Rather than minimising the delay overeach individual wire, the configuration that maximises thetotal bandwidth over a number of parallel wires isinvestigated. It is shown from simulations that there is aunique optimal solution which does not necessarily translate tothe maximum possible number of wires, and in fact deviatesconsiderably from it when the resources available for repeatersare limited. Analytic guidelines dependent only on processparameters are derived for optimal sizing of wires andrepeaters.Finally regular tiled architectures with a commoncommunication backplane are being proposed as being the mostefficient way to implement systems-on-chip in the deepsubmicron regime. This thesis also considers the feasibility ofimplementing a regular packet-switched network-on-chip in atypical future deep submicron technology. All major physicalissues and challenges are discussed for two differentarchitectures and important limitations are identified.
The Relationship Among Message Equivocality, Media Selection, and Manager Performance: Implications for Information Support Systems.

Abstract : A field study of 95 middle-level and upper-level managers was undertaken to explain top managers' selection of communication media. The findings indicate that media vary in their capacity to convey information cues, and that media richness is correlated with message equivocality. Managers prefer rich media for equivocal communications and less rich media for unequivocal communications. The data suggest that high performing managers are more sensitive to the relationship between message equivocality and media richness than low performing managers. Implications for managers' use of information systems and electronic media are discussed.
Integration of uni-directional wireless systems within heterogeneous networks

Mobile data networks in the recent years have been kind of networks most developed due to advantage in flexibility and price of infrastructure. Technologies like WLAN that nowadays can be found in the most of the homes, the number of hotspots has been dramatically increased and also there are implementing new technologies as WiMAX have been role out by network operators to reach more coverage and capacity in order to bringing wireless access networks near to their users. A becoming mobile broadcast technology is DVB-H (Digital Video Broadcast - Handheld) that provide digital television, it is also interesting for operators because can achieve large number of users with minimum investment in infrastructure. Another aim of companies is to develop a heterogeneous wireless access network that users will be able to connect through the best available technology. In order to integrate these technologies in the heterogeneous wireless environment requires to provide mechanisms to allow network's interoperability. Create a seamless and transparent inter-system handover for the users is can be possible deploying a framework developed by IEEE 802.21 group. In addition, there is a problem that has to be considered. 802.21 framework cannot work on broadcast systems, must be required to implement a mechanism called Uni-Directional Link Routing created by the IETF in order to simulate bidirectional communication in unidirectional scenarios. First of all, in this essay, there is a description of several mobile data networks that can find on heterogeneous networks like the 802.11 family, IEEE 802.16 and the broadcast service to transmit digital television into handheld (DVB-H). In the second part, it is explained the different mechanisms to support mobility in heterogeneous unidirectional systems: IEEE 802.21 and UniDirectional Link Routing. Finally, there is practical part created by the tool "Network Simulator - NS2" simulating the traffic behavior in unidirectional systems.
Fibulin 2 Is Hypermethylated and Suppresses Tumor Cell Proliferation through Inhibition of Cell Adhesion and Extracellular Matrix Genes in Non-Small Cell Lung Cancer

Fibulins (FBLNs), interacting with cell adhesion receptors and extracellular matrix (ECM) components, play multiple roles in ECM structures and tissue functions. Abnormal expression of FBLN2, one of the fibulin family members, contributes to tumor initiation and development. However, the function of FBLN2 in human non-small cell lung cancer (NSCLC) has not yet been elucidated. In this study, we found that FBLN2 was downregulated in 9 out of 11 lung cancer cell lines compared to normal bronchial epithelial cells, which was associated with DNA hypermethylation. Primary lung squamous cell carcinoma expressed significantly more FBLN2 protein compared to adenocarcinoma (p = 0.047). Ectopic expression of FBLN2 led to decreased cell proliferation, migration and invasion, accompanied by inactivated MAPK/ERK and AKT/mTOR pathways, while FBLN2 siRNA knockdown resulted in an opposite biological behaviour in NSCLC cells. Additionally, overexpression of FBLN2 led to dysregulation of cell adhesion molecules, ECM markers and a panel of lysate/exosome-derived-microRNAs, which are involved in cell adhesion and ECM remodelling. Taken together, our data indicate that FBLN2 is methylated and exerts a tumor suppressor function through modulation of MAPK/ERK and AKT pathways and regulation of cell adhesion and ECM genes. Moreover, FBLN2 might be a potential biomarker for the sub-classification of NSCLC.
AIS Electronic

In the future, a core criterion for the success of electronic marketplaces and distribution channels will be semantic interoperability among different vendors’ EC systems. In this context, interoperability of product catalogs is of particular importance as it holds an enormous business potential for the transformation of sourcing processes of distributors and large organizations and can enable a wide variety of new business models in areas such as purchasing and sales operations. The case of Hofer-Curti Group, a large Swiss trade group, provides an exemplary scenario for the streamlining and optimization of supply chain activities enabled by interoperable catalog technology.
Tunneling

Consider a ball rolling from one valley to another over a hill (Figure \(\PageIndex{1}\)). If the ball has enough energy (\(E\)) to overcome the potential energy (\(V\)) at the top of the barrier between each valley, then it can roll from one valley to the other. This is the classical picture and is controlled by the simple Law of Conservation of Energy approach taught in beginning physics courses. However, If the ball does not have enough kinetic energy (\(E<V\)), to overcome the barrier it will never roll from one valley to the other. In contrast, when quantum effects are taken into effect, the ball can "tunnel" through the barrier to the other valley, even if its kinetic energy is less than the potential energy of the barrier to the top of one of the hills.
Roadmap to FAIR Research Information in Open Infrastructures

ABSTRACT The FAIR Principles were designed to improve the findability, accessibility, interoperability and reusability of data holdings by humans and machines. The principles can be applied to research information too. We present the results of the discussions that took place during the series of online workshops with experts on Research Information and FAIR Guiding Principles. We provide high-level criteria on how to foster findable, accessible, interoperable and reusable, and we hope that our roadmap for FAIR research information in open infrastructures bring many benefits to a diverse group of stakeholders of the scientific ecosystem.
Training Interventions to Reduce Air Force Predator Mishaps

Abstract : The use of unmanned aerial systems (UASs) is expanding rapidly. In military operations, this increased use was often accompanied by relatively high mishap rates compared with rates across more mature manned aircraft. These higher rates led to multiple high-level reviews of unmanned operations to understand the issues, but surprisingly little consensus emerged across reports regarding root causes. To help close this gap, Air Force Predator Class A mishap reports through FY 2006 were analyzed in detail. Mishap rates, counts, and causal factors were all found to shift systematically over time, with a rise in mishap reports citing shortfalls in several skill and knowledge areas in FY 2004-2006. Individual and team Predator training objectives were revisited and the content of crew resource management (CRM) training was refocused on improving these key operator skills. In FY 2007-2008, Predator Class A mishaps attributed to operator error decreased despite increasing numbers of mishaps overall.
THE HARDWARE-SOFTWARE COMPLEX FOR TEACHING OF FAULT-TOLERANT SYSTEMS DEVELOPERS

In this paper the hardware-software complex is presented. It has been developed to teach developers of technical systems to effective fault-tolerant approach [Kulik, 1991] and [Kulik and Kozij, 1996], applied to a gyroscopic sensors unit (GSU). The fault-tolerant method used on the complex has the ability to perform a complete diagnosis of the GSU, constantly monitoring its state by means of several comparisons, determining the possible existence of a fault in the unit. Once a fault in the unit has occurred, the method is able to find where the fault is located; allowing us to define what kind of fault has appeared in the unit and this diagnosis can lead us to perform the proper corrective actions to recover the optimal performance of the GSU.
The Evolutionary Volte-Face of Transposable Elements: From Harmful Jumping Genes to Major Drivers of Genetic Innovation

Transposable elements (TEs) are self-replicating DNA elements that constitute major fractions of eukaryote genomes. Their ability to transpose can modify the genome structure with potentially deleterious effects. To repress TE activity, host cells have developed numerous strategies, including epigenetic pathways, such as DNA methylation or histone modifications. Although TE neo-insertions are mostly deleterious or neutral, they can become advantageous for the host under specific circumstances. The phenomenon leading to the appropriation of TE-derived sequences by the host is known as TE exaptation or co-option. TE exaptation can be of different natures, through the production of coding or non-coding DNA sequences with ultimately an adaptive benefit for the host. In this review, we first give new insights into the silencing pathways controlling TE activity. We then discuss a model to explain how, under specific environmental conditions, TEs are unleashed, leading to a TE burst and neo-insertions, with potential benefits for the host. Finally, we review our current knowledge of coding and non-coding TE exaptation by providing several examples in various organisms and describing a method to identify TE co-option events.