Miracle-dz/UniFAR-FTUs huggingface dataset:
Steady-State Analysis of Class-E/Fn Inverter with MOSFET Nonlinear Output Capacitance at any Grading Coefficient

In this paper, the analysis and design of a class-E/F n inverter using analytically expressions is provided for any grading coefficient m of the MOSFET body junction diode at 50% duty ratio. Generally, the class-E zero-voltage switching (ZVS) and zero-derivative voltage switching (ZDVS) conditions prepared the switch-mode operation inverter to obtain high power conversion efficiency performance. On the other hand, harmonics tuning and waveforms shaping in the load-network lead to the class-F inverter configuration. The combination of the switch-mode operating with waveforms shaping provides the class E/F n inverter. The MOSFET nonlinear drain-source parasitic capacitance is highlighted as determinative element in this operation mode. The nonlinearity characteristic of the MOSFET drain-source parasitic capacitance is required to include as the design specification for the satisfaction of the peak switch voltage and output power simultaneously. Furthermore, the grading coefficient m has considerably and directly made effects on both the output power capability and maximum operating frequency. The design and implementation of the class-E/F 3 inverter using the grading coefficient m as an adjustment parameter is performed. The close agreement between the analytical and PSpice simulations proved the effectiveness of the provided theoretical expressions. Therefore, the usefulness of analytical expressions is confirmed by high accuracy obtaining results from the laboratory measurements for the prototype fabricated circuit.
Integrating phylogeographic and ecological niche approaches to delimitating cryptic lineages in the blue-green damselfish ([i]Chromis viridis[i])

1 Department of Marine Biotechnology and Resources, National Sun Yat-Sen University, Kaohsiung, Taiwan 2 Biodiversity Research Center, Academia Sinica, Taipei, Taiwan 3 Center for Fisheries Research, Ministry of Marine Affairs and Fisheries, Jakarta, Indonesia 4 Department of Ecology and Evolutionary Biology, University of California, Los Angeles, LA, United States 5 The Indonesian Biodiversity Research Centre, Udayana University, Bali, Indonesia
Enzyme-Assisted Amplification and Copper Nanocluster Fluorescence Signal-Based Method for miRNA-122 Detection

At present, a large number of studies have demonstrated that miRNAs can be used as biological indicators for the diagnosis and treatment of diseases such as tumours and cancer, so it is important to develop a new miRNA detection platform. In this work, miRNA-122 is used as the basis for targeting detection agents. We have designed an unlabelled DNA1 that undergoes partial hybridisation and has a 20 T base long strand. The fluorescent signal in this experiment is derived from copper nanoclusters (CuNCs) generated on the circular T-long strand of DNA1. At the same time, DNA1 is able to react with miRNA-122 and achieve hydrolysis of the part bound to miRNA-122 via the action of nucleic acid exonuclease III (Exo III), leaving a part of the DNA, called DNA3, while releasing miRNA-122 to participate in the next reaction, thus achieving circular amplification. DNA3 is able to react with DNA2, which is bound to streptavidin magnetic beads (SIBs) and separated from the reaction solution via the application of a magnetic field. Overall, this is a fluorescence signal reduction experiment, and the strength of the fluorescence signal from the copper nanoclusters can determine whether the target miRNA-122 is present or not. The degree of fluorescence reduction indicates how much DNA1, and thus the amount of target miRNA-122, has been hydrolysed. By evaluating the variations in the fluorescence signal under optimised conditions, we discovered that this method has good sensitivity, with a detection limit as low as 0.46 nM, better than many other previous works on fluorescence signal-based biosensors for miRNA detection. This technique offers high discrimination and selectivity and can serve as a persuasive reference for early diagnosis.
The Effect of Month of Harvesting and Temperature–Humidity Index on the Number and Quality of Oocytes and In Vitro Embryo Production in Holstein Cows and Heifers

Simple Summary There are several factors that can affect embryo production; among the most important causes is heat stress (HS), which is related to a decrease in the quality and number of embryos produced. HS occurs when animals are exposed to temperatures that exceed their thermal comfort threshold or when body temperature rises or falls from the thermoneutral zone (TNZ) of the animal. It has been observed that a high ambient temperature can cause reversible or irreversible cell damage in different structures and organelles of the embryo. However, there is no information on which month of the year can most negatively affect embryo production. In this sense, the results obtained in our research reaffirm that high-yielding dairy cows in a hot-arid environment at 25 °N are susceptible to heat load, which is reflected in the lower number and quality of oocytes harvested by ovum pick-up and the in vitro resultant embryos. Abstract The aim of this study was to evaluate the effect of the month of oocyte harvesting and the temperature–humidity index on oocyte number and quality harvested from Holstein cows and heifers, oocyte developmental competence, and total embryos produced in an area of intense ambient temperature for most of the year. A total of 5064 multiparous lactating cows and 2988 nulliparous heifers were used as oocyte donors and distributed across the months of the year. Overall, total oocytes per collection did not differ (p > 0.05) between cows (16.6 ± 2.7) and heifers (15.1 ± 1.8), but oocyte developmental competence was lower (p < 0.05) in cows (21.3 ± 5.4) than heifers (25.5 ± 4.0). For cows, the total number of oocytes harvested was two-fold higher (p < 0.05) in November than in May. For heifers, the total number of oocytes harvested was highest in April (17.19 ± 0.53) and lowest in May (10.94 ± 0.32; p < 0.05). For cows, total embryos were highest in November (2.58 ± 0.42) and lowest in August (1.28 ± 0.10; p < 0.05). Thus, taken together, these results indicate that severe heat stress impaired the number and quality of oocytes harvested from donor Holstein multiparous cows and heifers, oocyte developmental competence, and total embryos produced in this area of intense ambient temperature for most of the year.
Intelligent Event-Triggered Control Supervised by Mini-Batch Machine Learning and Data Compression Mechanism for T-S Fuzzy NCSs Under DoS Attacks

This article presents a comprehensive solution to mitigate network congestion in T-S fuzzy networked control systems caused by denial-of-service (DoS) attacks and quality-of-service (QoS) queuing mechanisms. We develop a novel data compression mechanism to alleviate network congestion and use a mini-batch descent gradient algorithm to optimize trigger thresholds, thereby reducing bandwidth usage. In addition, we introduce asymmetric Lyapunov–Krasovskii functions to decrease the number of decision variables, which improves the reliability and robustness of the control algorithm. Finally, we propose an intelligent event-triggered controller supervised by mini-batch machine learning and validate it on the joint CarSim–Simulink platform. Experimental results demonstrate that our approach reduces the sensitivity of autonomous vehicle systems to network fluctuations while ensuring system stability under network congestion caused by DoS attacks.
Artistic Abilities and General Self-Esteem of Students of Art Academies / Umjetničke sposobnosti i opće samopoštovanje studenata umjetničkih akademija

The first aim of this paper is to examine the correlation between artistic ability and general self-esteem and the second aim of the study is to examine gender differences in the self-perception of artistic ability among students of art academies. The study involved 215 students of art academies (140 female students; mean age 22.54) from Osijek and Zagreb. Students completed the adult version of the Arts Self-Perception Inventory (Vispoel, 1996) and the Rosenberg Self-Esteem Scale (Rosenberg, 1965). The results show that artistic abilities are significantly and positively related to self-esteem, with music, dance, and general skills having the highest correlation with a sense of self-worth. Male students rate themselves higher than female students in the field of music and drama, and female students compared to male students in the field of visual art skill. In the field of dance and general artistic ability, no gender differences were found. Keywords: art; differences; female; male; self-perception. Â ---Â Prvi je cilj ovoga rada istražiti korelacije između umjetničkih sposobnosti i općega samopoštovanja, dok je drugi cilj studije istražiti spolne razlike u percepciji vlastitih umjetničkih sposobnosti kod studenata umjetničkih akademija. U istraživanju je sudjelovalo 215 studenata umjetničkih akademija (140 studentica, prosječne dobi 22,54) iz Osijeka i Zagreba. Studenti su ispunili Inventar samoprocjene umjetničkih sposobnosti (Vispoel, 1996) i Rosenbergovu skalu samopoštovanja (Rosenberg, 1965). Rezultati su pokazali kako su umjetničke sposobnosti značajno pozitivno povezane sa samopoštovanjem, gdje glazbene i opće umjetničke sposobnosti pokazuju najviše korelacije s osjećajem vlastite vrijednosti. Studenti su percipirali svoje glazbene i glumačke sposobnosti boljima od studentica, dok su studentice percipirale svoje likovne sposobnosti boljima u odnosu na studente. U područjima plesa i općih umjetničkih sposobnosti nisu pronađene spolne razlike. Ključne riječi: muškarci; razlike; samoprocjena; umjetnost; žene.
Marine Natural Compound (Neviotin A) Displays Anticancer Efficacy by Triggering Transcriptomic Alterations and Cell Death in MCF-7 Cells

We investigated the anticancer mechanism of a chloroform extract of marine sponge (Haliclona fascigera) (sample C) in human breast adenocarcinoma (MCF-7) cells. Viability analysis using MTT and neutral red uptake (NRU) assays showed that sample C exposure decreased the proliferation of cells. Flow cytometric data exhibited reactive oxygen species (ROS), nitric oxide (NO), dysfunction of mitochondrial potential, and apoptosis in sample C-treated MCF-7 cells. A qPCR array of sample C-treated MCF-7 cells showed crosstalk between different pathways of apoptosis, especially BIRC5, BCL2L2, and TNFRSF1A genes. Immunofluorescence analysis affirmed the localization of p53, bax, bcl2, MAPKPK2, PARP-1, and caspase-3 proteins in exposed cells. Bioassay-guided fractionation of sample C revealed Neviotin A as the most active compound triggering maximum cell death in MCF-7, indicating its pharmacological potency for the development of a drug for the treatment of human breast cancer.
Social Support for Birthmothers Before and During the COVID-19 Pandemic

Giving birth is not a simple event and requires much attention, care, and support to result in a positive birth experience. However, the process of giving birth changed significantly during the COVID-19 pandemic due to the spread of the virus, the uncertainty of the virus, and the numerous restrictions implemented. These led to isolation, loneliness, a lack of communication, loss of control over the body, and little or no contribution to decision-making for the new birth mother. This, as well as a lack of social support, can harm a mother’s and baby’s mental and physical health. Thus, this article explores the importance of social support and its role before the COVID-19 pandemic, as well as the changes that have occurred in the birth process during the COVID-19 pandemic.
Surface uplift in world’s youngest orogen, can crustal thickening explain the uplift in Timor?

The island of Timor, SE Asia is the result of Arc-continent collision of the Banda Arc with the Australian Continental margin. Shortening of the Australian plate strata leads to thickening of the crust. Assuming isostasy, this should cause uplift. We hypothesize that the uplift of Timor can be explained by the built-up of a fold-and-thrust belt. During this built up sedimentation of basins which structurally lie on top of this fold-and-thrust belt, was taking place. These synorogenic basins, known as the Viqueque formation, are passive recorders of the uplift history. We reconstruct the uplift history by building an age model for the Viqueque formation and using occurrences of depth markers (benthic foraminifera). Combining the age model with depth differences allows us to reconstruct the uplift history. Timor has experienced uplift in two phases: a phase with almost no significant uplift and generally very low uplift rates during the deposition of the lower part of the Viqueque formation, followed by a phase of rapid uplift, up to ~3 mm/yr. The fold-and-thrust belt has been thickened by an average thickening factor of 3.3. If we assume Airy-type isostasy, and that thickening starts around the first deposition of Viqueque strata, we find a theoretical uplift rate of around ~0.4 mm/yr. Homogeneous thickening of the fold-and-thrust belt alone might be enough to explain the low uplift rates in the lower part of the Viqueque formation. But it is not enough to explain the phase of rapid uplift. Another process is likely the cause for the observed uplift. Activation of the Wetar thrust might explain the uplift, but this is poorly constraint. Slab detachment is unlikely the cause because there is no evidence that the slab has broken off. Timor’s position in the Banda-Arc Australia collision zone makes delamination the most likely process. But further research is needed to strengthen this hypothesis.
Selection of bacterial strains to bioaugment granular sludge and improve the removal of recalcitrant pollutants

Several advantages are gained by the use of granular sludge in wastewater treatment plants (WWTP), such as higher biomass retention, faster settling properties, lower energy costs and smaller operational land space. However, relatively few studies have been carried out on the biodegradation of recalcitrant pollutants in these systems, compared to research performed on conventional WWTP with floccular sludge. For instance, bioaugmentation of bacterial strains with metabolic abilities of interest in biological reactors for wastewater treatment has been intensively studied in conventional WWTP systems, but not in systems with granular sludge. In the project “Bioaugmentation and conjugative plasmid transference using bacteria from extreme environments to enhance biodegradation of recalcitrant pollutants in WWTP granular sludge”, funded by the Portuguese Foundation for Science and Technology, a group of bacterial strains showing potential capacity to metabolize recalcitrant pollutants (paracetamol, ibuprofen, fluoxetine and polyethylene terephthalate) was isolated and their genomes are being sequenced with the aim of identifying genes putatively involved in the metabolic pathways of interest. In addition, biodegradation experiments are being performed in laboratory-scale granular sludge bioreactors bioaugmented with selected isolates.
Epidemiology of Injuries in Men’s Professional and Amateur Football (Part I)

Background (1): Football is the most popular sport among men, associated with a certain risk of injury, which leads to short- and long-term health consequences. While the injury profile of professional footballers is known, little is known about the injury profile of amateur footballers; amateur football is a major and diverse area, the development of which should be a priority for football associations around the world and UEFA. The aim of this study was to perform a systematic review of epidemiological literature data on injuries in professional and amateur football players belonging to certain leagues. Methods (2): A systematic review according to the PRISMA guidelines was performed until June 2023 in the databases PubMed, Web of Science, Google Academic, Google Scholar, and Diva portal. Forty-six studies reporting injury incidence in professional and amateur men’s football were selected and analyzed. Two reviewers independently extracted data and assessed study quality using an adapted version of the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement and the Newcastle Ottawa Scale (NOS) to assess risk of bias for the quality of external validity. Results (3): The overall incidence of injuries in professional male football players was 7.75 ± 2.28, 95% confidence interval, injuries/1000 h of exposure and that of amateur football players was 7.98 ± 2.95, 95% confidence interval, injuries/1000 h of exposure. The incidence of match injuries (30.64 ± 10.28, 95% confidence interval, injuries/1000 exposure hours) was 7.71 times higher than the training injury incidence rate (3.97 ± 1.35, 95% confidence interval, injuries/1000 h) in professional football players and 5.45 times higher in amateurs (17.56 ± 6.15 vs. 3.22 ± 1.4, 95% confidence interval, injuries/1000 h). Aggregate lower extremity injuries had the highest prevalence in both categories of footballers, being 83.32 ± 4.85% in professional footballers and 80.4 ± 7.04% in amateur footballers: thigh, ankle, and knee injuries predominated. Conclusions (4): Professional and amateur football players are at substantial risk of injury, especially during matches that require the highest level of performance. Injury rates have implications for players, coaches, and sports medicine practitioners. Therefore, information on football injuries can help develop personalized injury risk mitigation strategies that could make football safer for both categories of football players. The current findings have implications for the management, monitoring, and design of training, competition, injury prevention, especially severe injury, and education programs for amateur football players.
Sarcopenia Adversely Affects Outcomes following Cardiac Surgery: A Systematic Review and Meta-Analysis

Background: Sarcopenia is a degenerative condition characterised by the loss of skeletal muscle mass and strength. Its impact on cardiac surgery outcomes remains poorly investigated. This meta-analysis aims to provide a comprehensive synthesis of the available evidence to determine the effect of sarcopenia on cardiac surgery outcomes. Methods: A systematic review and meta-analysis followed PRISMA guidelines from inception to April 2023 in EMBASE, MEDLINE, Cochrane database, and Google Scholar. Twelve studies involving 2717 patients undergoing cardiac surgery were included. Primary outcomes were early and late mortality; secondary outcomes included surgical time, infection rates, and functional outcomes. Statistical analyses were performed using appropriate methods. Results: Sarcopenic patients (906 patients) had a significantly higher risk of early mortality (OR: 2.40, 95% CI: 1.44 to 3.99, p = 0.0007) and late mortality (OR: 2.65, 95% CI: 1.57 to 4.48, p = 0.0003) compared to non-sarcopenic patients (1811 patients). There were no significant differences in overall surgical time or infection rates. However, sarcopenic patients had longer ICU stays, higher rates of renal dialysis, care home discharge, and longer intubation times. Conclusion: Sarcopenia significantly increases the risk of early and late mortality following cardiac surgery, and sarcopenic patients also experience poorer functional outcomes.
Novel use of probiotic as acetylcholine esterase inhibitor and a new strategy for activity optimization as a biotherapeutic agent

The communication between the central nervous system and the gastrointestinal organs was first introduced in the 1880s. Further studies followed to ascertain the influence of gut flora on the host`s brain functions, general behavior, and neurodegenerative diseases. Article objectives involved investigate a new promising probiotic as an anti-acetylcholine esterase, and maximize its activity using optimization statistical approaches. Probiotics isolates from different sources underwent anti-acetylcholine esterase activity screening by modified Ellman’s method. Where 14 out of the investigated strains showed acetylcholine esterase inhibition (AChEI) activity ranging between 0.407% ± 0.004% for the lowest inhibiting strain (PI22) to 9.846% ± 0.135 for the highest inhibiting strain (PI09). ANOVA analysis and post-ANOVA comparisons showed a significant difference in AChEI% between the tested strains ( P < 0.001). Taguchi experimental design used to study the effect of each factor and their interactions on the AChEI activity and to enhance the inhibition activity of PI09 strain. ANOVA analysis showed that inoculum size power had a significant effect ( P < 0.05) on the AChEI%. AChEI% activity for the isolate PI09 was successfully maximized by 60% from 9.846% ± 0.135% to 16.55% ± 0.07%. Finally, the most potent strain (PI09) was identified through 16S rRNA sequencing, aligned using the EZbio database, and identified as Levilactobacillus brevis . This is the first report about probiotics activity against acetylcholine esterase results revealed that the screened isolates specially Levilactobacillus brevis might have anti-acetylcholine esterase activity, which can allow usage of the probiotics as an auxiliary drug against AD, or to be used for large scale production of AChEIs in the future.
Tropical Estuarine Fishes: Ecology, Exploitation and Conservation

Series Foreword. Preface and Acknowledgements. 1. Scope and Definitions. 2. The Diversity of tropical Estuaries. 3. Fish Faunas and Communities. 4. Trophic Ecology. 5. Reproductive Strategies. 6. Effects of Structure and Hydrology. 7. Mangroves and Estuarine Dependence. 8. Estuarine Fisheries. 9. Effects of Fishing. 10. Effects of Industry and Agriculture. 11. Conservation, Rehabilitation and Climate Change. References. Taxonomic Index. Geographic Index. Subject Index.