Miracle-dz/UniFAR-FTUs huggingface dataset:
Rare Complications of Acute Appendicitis: A Case Report.

INTRODUCTION Appendicitis is a common disease, and as we have improved in early diagnosis and management of this disease process, late stage complications have become extremely rare, but can have indolent presentations. CASE REPORT A 37-year-old male with no past medical history presented to the emergency department (ED) with vague abdominal pain as well as 12 days of cyclical fever. He had no significant findings on laboratory workup with the exception of a mild aspartate transaminase and alanine transaminase and relative neutrophilia between outpatient, urgent care, and ultimate ED visit. His ED workup included cross-sectional imaging of his abdomen revealing multiple liver abscesses and septic thrombophlebitis secondary to ruptured appendicitis. CONCLUSION Liver abscesses and septic thrombophlebitis are an extremely rare complication of appendicitis that has only been documented twice previously.
Effect of Amiodarone on Rat’s Isolated Tracheal Smooth Muscle

Background: Amiodarone is considered the most effective agent to treat supraventricular and ventricular arrhythmia and prevent atrial fibrillation. The blockade of the potassium channel to elongate the refractory period of the myocardium is widely known. Its peculiar pharmacokinetics and toxicity cause some problems to clinicians. The effect on the myocardium, thyroid gland, and lung has been well explored. However, the effect of amiodarone on the tracheal smooth muscle is not well investigated. Methods: We studied the effectiveness of amiodarone on rat’s isolated tracheal smooth muscle as our preparation. The following assessment of amiodarone were performed: (1) effect on the tracheal smooth muscle resting tension; (2) effect on contraction induced by 10 -6 M methacholine as a parasympathetic mimetic; (3) effect on electrically induced tracheal smooth muscle contractions. Results : The addition of amiodarone at a low dose made no difference to the resting tension of trachea smooth muscle. At 10 -4 M of amiodarone, temporary tracheal smooth muscle contraction was detected. When the concentration of amiodarone increased to 3 x 10 -4 M, the tracheal smooth muscle relaxed following the brief contraction. For the electrical stimulation and 10 -6 M methacholine-induced contraction tests, the amiodarone elicited no scientific change on trachea smooth muscle contraction with increasing concentration. Conclusion: In the animal model, amiodarone doesn’t change physiologic mechanism of trachea smooth muscle at therapeutic concentration. may cause thyrotoxicosis in geographical areas with low iodine intake. Besides, this lipophilic agent is a strong inhibitor of lysosomal phospholipase A1 and A2. It can induce direct damage through accumulating in lysosomes, and disturbing metabolic processes, changing the physical properties of cell membranes, inhibiting mitochondrial function, resisting calcium homeostasis, producing reactive oxidant species, and inducing apoptosis [4]. One cause of asthma is contraction of the trachea by parasympathetic dysautonomia [5]. Suppressing the parasympathetic tone can release the asthmatic symptoms. Amiodarone is a complex drug extensively used during resuscitation. The anti-arrhythmic effect of this first aid medicine is well explored, but the effect on the trachea smooth muscle is still unknown. We wanted to research if amiodarone could affect the trachea smooth muscle. The previously documented papers demonstrated one direct and sufficient method to determine the effects of amiodarone on isolated trachea smooth
STUDY OF SERUM FERRITIN IN METABOLIC SYNDROME AND ITS COMPONENTS

: BACKGROUND AND OBJECTIVES : The metabolic syndrome is a cluster of risk factors for cardiovascular disease (CVD). The present study was aimed to know the relationship between serum ferritin and metabolic syndrome and to evaluate its relationship with individual component of metabolic syndrome. METHODOLOGY: The present study was conducted in the Department of Medicine. SS Institute of Medical Sciences and Medical Research Centre, Davangere during the study period from January 2014 to December 2014. Based on NCEP ATP III criteria, 100 cases with metabolic syndrome were enrolled. Serum ferritin was measured on fasting blood samples using radio-immunoassay. RESULTS: In this study, male preponderance was noticed. The most common age group was 51 to 60 years (30%) and overall, the mean age was 55.84±15.04 years. The commonest component of metabolic syndrome was hypertension 88%. Lipid abnormalities revealed raised serum cholesterol, LDL, TG and low HDL among 61%, 15%, 86% and 81% respectively. Results of the present study showed serum ferritin was elevated significantly in individual components of metabolic syndrome (Hypertension, waist circumference, low HDL levels) though serum ferritin were elevated in patients of FBS and Triglyceride abnormality, but it was of statistically insignificant. but was individual components of metabolic syndrome. thorough clinical examination was conducted. and recorded and mass mass kg/m underweight, 29.9 kg/m 2 obese. circumference using a standard measuring tape in cms. circumference cm 40 inches (male), ≥88 36 inches (female) abnormal.
An I/O Separation Model and its Applications to On-Demand I/O on Commodity Platforms

A key goal of security architectures is to separate I/O transfers of security-sensitive applications from untrusted commodity OSes and other applications, with high assurance. These architectures provide I/O kernels that assure the confidentiality and authenticity of the transmitted I/O data owned by a securitysensitive application, even when commodity OSes and other applications are compromised. These kernels help eliminate security-sensitive application exposure to drivers they do not need. This is a major security advantage because drivers contribute over half of code size in commodity OS kernels. However, existing I/O kernels can only enforce I/O separation on limited hardware configurations of commodity platforms, if they rely on existing I/O hardware mediation components such as IOMMU, or ignore I/O operations that could be misused to break I/O separation. Commodity I/O hardware designs focus primarily on increasing performance and device connectivity, but often fail to separate I/O transfers of isolated OS and applications code. Even when using the best I/O hardware, commodity systems sometimes trade off isolation assurance for increased performance. Remarkably, to breach I/O separation, device firmware need not be malicious, though it is allowed to be so. Instead, any malicious driver can manipulate its device to breach I/O separation. To prevent such vulnerabilities in kernel designs with high assurance, a formal I/O separation model is necessary. This dissertation defines an I/O separation model for general commodity platforms and proves its soundness. The model defines a precise separation policy based on complete mediation of I/O transfers despite frequent lack of commodity hardware to support it. Thus it can be applied to the I/O designs of all commodity platforms, compared to previous kernels that work on limited hardware configurations. Furthermore, this dissertation applies the model to the latest I/O kernels that offer on-demand I/O separation. These kernels allow security-sensitive applications to relinquish and release their devices to and from untrusted commodity OSes on-demand. The dissertation shows how to apply the I/O separation model to one carefully but informally designed on-demand I/O kernel, the Wimpy Kernel, and illustrates how the model enables the discovery of formerly unknown vulnerabilities. The dissertation also shows how to remove these vulnerabilities and obtain a model-based I/O design – an unavailable feature of commodity systems. In addition, the dissertation presents a novel GPU Separation Kernel to allow isolated applications to share display with untrusted OS and other applications, and informally analyzes it against the same vulnerabilities.
Group activity recognition with an interaction force based on low‐level features

Group activity recognition of humans is an important task for video surveillance systems. In complex situations, however, ambiguities usually arise as a result of chaotic movements in the scene, especially when it is solved based upon motion trajectory analysis involving object segmentation and tracking. In this work, we present an interaction force model (IFM) to recognize group activity using low‐level feature based on dense optical flow. The IFM used to define interaction among people consists of three principal forces: group motion force (GMF), interaction motion force (IMF), and reciprocal motion force (RMF), to model the behaviors of the activity. Our algorithm is evaluated using the well‐known NUS‐HGA and BEHAVE datasets. Results of our approach reveal good efficiency with high accuracy, regardless of the surrounding conditions, and is competitive with other state‐of‐the‐art methods. © 2019 Institute of Electrical Engineers of Japan. Published by John Wiley & Sons, Inc.
ANTIMICROBIAL TOXICITIES: COMMON SIDE EFFECTS & ALLERGIC REACTIONS

of side are diverse of unrelated properties of unique chemical new mitochondrial alterations form the for of topoisomerases) little homology with prokaryotic ABSTRACT The overall incidence of ADRs to antimicrobials increases day by day. Generalized adverse events are common to most antibiotics (e.g., gastrointestinal distress with any oral antibacterial drug), but certain antibiotics are associated with specific effects. Some adverse events are mild, e.g., yellowing of the teeth for tetracyclines. More serious side effects include photosensitivity and anaphylactic reactions observed with many agents, ototoxicity following aminoglycoside therapy, chondrotoxicity and retinopathy with fluoroquinolones. Penicillins are known to cause a wide spectrum of neurotoxic manifestations including encephalopathy, behavioural changes, myoclonus, seizures as well as NCSE. Populations at risk of neurotoxicity associated with various groups of antibiotics include those with extremes of age, critical illness, renal dysfunction and prior neurological disease. Knowledge of neurotoxic effects is essential for clinicians in order to avoid this preventable complication. Knowledge of selection of an appropriate antibiotic, pharmacokinetics and dosage adjustments in those at risk may aid in the prevention of toxicity associated with these drugs.
Miniaturized Bagley Polygon power divider by using composite right-/left-handed transmission lines

A miniaturized Bagley Polygon power divider based on composite right/left-handed transmission line is presented. The composite right/left-handed transmission line and conventional microstrip transmission line are utilized to realize the 0° phase shift transmission line, which is used to replace the 180° transmission line of the conventional Bagley Polygon power divider. As a result, miniaturization is realized, without deteriorating the isolation between the output ports. The design equations are presented. This power divider shows advantages compared with other miniaturized ones. For verification, a miniaturized Bagley Polygon power divider is designed and fabricated. The 58.2% length reduction of the counterpart is realized. The measurement and simulation results show good agreement.
Combining Fine Line Photoimageable with Multi-Step Thick Film for Improved Circuit Density

Abstract There is a strong market need for further miniaturization of microelectronic ceramic-based products; electronic components require an increasingly finer pitch interconnect. Screen-printing resolution is a limiting factor in further miniaturization of classical thick film. Photo imageable thick film technology (PITF) was proposed decades ago as a successor technology to thick film, to achieve finer pitch patterns. However, where classical multilayer thick film provides good routing and interconnect capabilities, but insufficient fine line resolution, PITF does the reverse: no multilayer routing but advanced fine line performance. A combination of PITF for fine pitch mounting with advanced MLTF for efficient routing has been developed, targeting a linewidth of 50 μm line/spaces and below. Test and demo panels were made, using combinations of PITF pastes and conventional screen-print materials. Results, process performance, and limiting factors are discussed.
Cross-country comparison of substitution patterns in the European car market

AIMS. Using recent data on sales, prices and product characteristics of new passenger vehicles sold in Europe’s seven largest markets during years 2000 through 2005, I estimate a demand function using two approaches to the differentiated product demand estimation: the Logit and the Nested Logit. For the Nested Logit model, I use nests that roughly correspond to segmentation used in the automobile industry. I then compare substitution patterns resulting from Logit and Nested Logit specifications across countries and segments. FINDINGS. Regression outcomes demonstrate strong evidence of segmentation. Consumer preferences are strongly correlated for the most basic as well as for the luxury and sports segments, whereas core segments display more heterogeneity. While car size preference varies across countries, Europeans typically like high and wide cars and dislike long cars. Engine performance appreciation appears to have a curved shape: consumers are willing to pay for a fast car but at a decreasing rate. Compared to their neighbors, Germans shop the most for premium brands yet display strongest price sensitivity, whereas most concerned about fuel consumption are the Brits. Aside from a few exceptions, all elasticities are within expected range, substitution patterns vary mainly across segments but follow a similar pattern across countries.
Identification, structure and characterization of an exopolysaccharide by Histophilus somni during biofilm formation.

Background: Histophilus somni , a gram-negative coccobacillus, is an obligate inhabitant of bovine and ovine mucosal surfaces, and an opportunistic pathogen responsible for respiratory disease and other systemic infections in cattle and sheep. Capsules are important virulence factors for many pathogenic bacteria, but a capsule has not been identified on H. somni . However, H. somni does form a biofilm in vitro and in vivo , and the biofilm matrix of most bacteria consists of a polysaccharide. Results: Following incubation of H. somni under growth-restricting stress conditions, such as during anaerobiosis, stationary phase, or in hypertonic salt, a polysaccharide could be isolated from washed cells or culture supernatant. The polysaccharide was present in large amounts in broth culture sediment after H. somni was grown under low oxygen tension for 4-5 days (conditions favorable to biofilm formation), but not from planktonic cells during log phase growth. Immuno-transmission electron microscopy showed that the polysaccharide was not closely associated with the cell surface, and was of heterogeneous high molecular size by gel electrophoresis, indicating it was an exopolysaccharide (EPS). The EPS was a branched mannose polymer containing some galactose, as determined by structural analysis. The mannose-specific Moringa M lectin and antibodies to the EPS bound to the biofilm matrix, demonstrating that the EPS was a component of the biofilm. The addition of N -acetylneuraminic acid to the growth medium resulted in sialylation of the EPS, and increased biofilm formation. Real-time quantitative reverse transcription-polymerase chain reaction analyses indicated that genes previously identified in a putative polysaccharide locus were upregulated when the bacteria were grown under conditions favorable to a biofilm, compared to planktonic cells. Conclusions: H. somni is capable of producing a branching, mannose-galactose EPS polymer under growth conditions favorable to the biofilm phase of growth, and the EPS is a component of the biofilm matrix. The EPS can be sialylated in strains with sialyltransferase activity, resulting in enhanced density of the biofilm, and suggesting that EPS and biofilm formation may be important to persistence in the bovine host. The EPS may be critical to virulence if the biofilm state is required for H. somni to persist in systemic sites. IS carried out the scanning qRT-PCR, electron microscopy, and biofilm studies, TJI was responsible for the identification and purification of the EPS and electrophoretic techniques, MAA and JQS carried out the freeze-fracture ITEM and lectin binding studies, and CDC carried out analytical and structural analyses of the EPS, ADC and FAM carried out analytical studies on the EPS and LOS, GB carried out preparation of the immune sera, ITEM of EPS on whole cells, and electrophoretic methods. IS, TJI, and
Approximation theory concepts of smoothness are of global nature

The main goal of this note is to prove that, in general, the smoothness concepts derived from membership to an approximation space, are of global nature. To prove this claim we show that if (C[a,b],{An}) is an approximation scheme and (An) satisfies de La Vallee-Poussin Theorem, there are very smooth functions (in the classical sense) failing the smoothness assumption just at one extreme point of the interval [a,b] but being continuous on [a,b] and such that their sequence of best uniform approximation errors {E(f,An)} decays as slow as we want. We also prove that a similar result holds true for the multidimensional case.
The efficiency of a long range facilities plan in an Abbott school district

Nancy B. Knarr-Pascoe The Efficiency of a Long Range Facilities Plan In an Abbott School District 2003/04 Dr. Dennis Hurley Master of Arts in School Business Administration ABSTRACT This study investigated the efficiency of the Long Range Facilities Plan (LRFP) for the Millville School District and sought to determine, through the creation of inventories, the completed and in progress facilities projects, in addition to those that will not be completed by the close of the district's current LRFP. On-going personal communication with the district's facilities coordinator provided continual updates on the status of all facilities projects within the district. In addition, this study examined both the New Jersey Administrative Code (NJAC) (6A:26-8.1) and documentation made available on the New Jersey Department of Education's (NJDOE) School Facilities Web site to determine if the Millville School District followed existing guidelines and submitted proper documents to the NJDOE. The study also determined whether or not the current LRFP has met the district's facilities needs, as required by the NJAC (6A:26-8.1) and Abbott v. Burke (1997, May). The research revealed that overall not all facilities projects would be completed by the expiration of the current LRFP in 2005 and, moreover, that this plan did not leave enough time to complete all of the necessary facilities projects in a five-year time frame as it proposed to be accomplished. As a result, remaining projects will need to be carried over into the next 5-year LRFP cycle.
Social Engineering Attacks: A Phishing Case Simulation

: In this paper, we discuss phishing as one of the attack types used in social engineering. Phishing attacks will be discussed by simulating a process between two different devices in two different networks. An experimental penetration test was performed on one of the local network devices to obtain data and information of the victim. The experiment involves sending fake email containing a link to a fake website in order to persuade the victim to enter personal data logs into the fake website. The experiment illustrates the ways in which an attacker may defraud the victim. In addition, the experiment contributes to the protection from and avoidance to exposure of this type of attack.
-1-Modulation of Ca 2+ channel currents by a novel anti-dementia drug FK960 in rat hippocampal neurons

-3-ABSTRACT FK960 (N-(4-acetyl-1-piperazinyl)-p-fluorobenzamide monohydrate), a novel anti-dementia drug, has been demonstrated to ameliorate memory deficits in various experimental models of dementia. This drug selectively increases somatostatin release from hippocampal slices and augments long-term potentiation (LTP) in the CA3 area of the hippocampus. In the present study, the effects of FK960 on voltage-activated Ca 2+ channels were investigated in acutely isolated rat hippocampal neurons, using whole-cell patch-clamp technique to clarify the cellular mode of action of FK960. Application of somatostatin significantly reduced Ca 2+ currents via G-protein-coupled signaling pathways. This inhibitory effect was completely abolished by FK960 when applied in combination. In contrast, FK960 showed only modest inhibition on the reduction in Ca 2+ currents produced by baclofen, an agonist of GABA B receptor. Intracellular application of the somatostatin-induced inhibition and had no significant effect on blockade by FK960. In addition, application of FK960 alone produced modest but apparent increases in Ca 2+ currents without significant changes in the activation kinetics of the channels. The dose-response relationship on calcium current enhancement was bell-shaped with a maximum effect at 0.1 µM FK960, the same concentration as that for increasing on somatostatin release and CA3-LTP. These results show that FK960 reverses G protein-dependent inhibition of Ca 2+ currents by somatostatin in hippocampal neurons. Enhancement of Ca 2+ currents by FK960 may be due to its modulatory actions on Ca 2+ channels, rather than removal of G-protein inhibited tonic currents. Taken together, these mechanisms may be involved in the selective effects of FK960 on somatostatin -4-release, excitatory transmission and synaptic plasticity in the hippocampus. -8-continually perfused with the external solution with or without test drugs through gravity-fed flow pipes at a constant flow rate. Unless indicated otherwise, whole-cell inward currents were elicited every 10 s by depolarization to 0 mV from a holding potential of –80 mV. Currents were four-pole Bessel-filtered and digitized at 10 kHz with DigiData 1200 Interface. Data were acquired and leak subtracted using the P/4 protocol under the control of the pCLAMP (6.0) software (Axon Instruments. U.S.A) using a personal computer. All experiments were carried out at room temperature (21-23°C). All data are presented as mean ± S.E. M, (n = number of cells in parentheses in the figures). Statistical analysis of data was performed using Student's t test or Dunnett’s multiple comparison test. A p value less than 0.05 was considered significant.
Static Malware Analysis to Identify Ransomware Properties

The study in this paper presents the results of ransomware analysis to identify the characteristic properties that distinguish ransomware executable from other malware and benign executables. The executables are analyzed both statically and dynamically to observe the typical structure and behavior of the ransomware. Static analysis is used to extract ransomware specific properties from the executable file. The inclusion of these properties with the set of generic malware properties has shown improved classification for malware detection specifically ransomware using well-proven software verification and validation techniques. Runtime analysis identifies the most common behavior of the ransomware. The paper is focused upon the ransomware attacks which have risen exponentially over the past decade with increasing severity. This has the conventional anti-malware techniques compelled to include advanced detection mechanisms for ransomware and this paper demonstrates a method to identify the properties related to such software environments.