Miracle-dz/UniFAR-FTUs huggingface dataset:
Cellular Stress Promotes Cellular Suicide: Review Article

The focus of this overview was to elucidate the different kinds of stresses that influence cell survival, growth, and cellular functions, in addition to cellular quiescence and cellular suicide, as well as how the cell tries to respond to these stressful stimuli. A cell's cycle is a sequence of developments that enables a cell to replicate every component of itself, divide into two nearly identical new cells, and endow each with the information and resources it needs to repeat the process. For tissue homeostasis, the ideal stabilization of proliferation of cells, demise of cells, and the proportion of positive to negative signals determines if the cell is alive or dead. Cells could indeed cope with adverse conditions in an assortment of ways, from triggering long-term survival strategies to establishing the demise of cells, which ultimately expel dead cells. The kind, intensity, and time frame of the stress, plus the kind of cell, all play a significant role in determining whether cells mount a defensive or destructive response to stress. This review will talk about the consequences of cellular responses to stress and discuss a range of stressful situations and the degree to which the animal's cells' react to multiple exhausting factors ranging from the physiologically programmed advancement of cells to cellular senescence and/or a variety of pathological disorders.
Surgical Root Coverage of Miller’s Class III Using Free Gingival Autograft (A Case Report)

Background: Gingival recession is a condition where the root surface of the tooth is exposed due to migration of the gingival margin and junctional epithelium in an apical direction. The problem that patients often complain about due to gingival recession is an aesthetic problem, especially if the recession occurs in the upper anterior teeth. In addition, gingival recession can also cause dentine hypersensitivity due to the exposure of the root surface that was previously covered by the gingiva. One of the treatment options for patients with gingival recession is free gingival autograft surgery. Purpose: The goal of this article is to explain how to manage gingival recession therapy with free gingival autograft surgery in patients with Miller Class III recession. Case: A 29-year-old female patient came to RSGM Airlangga University with complaints of hypersensitivity in the front teeth at the lower jaw. The last scaling took place about 6 months ago. The patient does not have a history of systemic diseases, such as hypertension and diabetes, and the patient does not have allergies to either drugs or food. Case Management: Based on the examination that has been carried out, the treatment option for Miller's class III gingival recession in the tooth region 41 is agreed to be a free gingival autograft. Conclusion: One of the root coverage treatment options is free gingival autograft, where this procedure can also increase the width of the attached gingiva.
International Journal of Current Science Research and Review

Instagram stands out as a prominent platform, offering companies a valuable space to promote their offerings to a vast and diverse audience. To capture consumer interest, Instagram advertisements now incorporate innovative interactive features and ephemeral effects, enhancing their appeal and engagement. The objective of this study is to examine the influence of interactivity and ephemerality of instagram advertisements in shaping perceived value and behavioral intention. A quantitative research approach was employed in this study. Data from 239 participants were gathered through an online survey and analyzed utilizing SmartPLS 3.2. 9 software employing Structural Equation Modeling. The findings indicate that the interactivity and ephemerality of Instagram Stories advertisements significantly influence three types of perceived value such as utilitarian, hedonic, and social value among female consumers of the fashion brand HeyLocal. Furthermore, these perceived values motivate positive behavioral intentions such as the intention towards social media activities, online search, and brand purchase. In contrast to social value, it was found that utilitarian and hedonic value do not directly impact brand purchase. In addition, our research revealed that consumers' purchase decisions can be reinforced through their engagement in social media activities and online information search.
Comparative Effectiveness of Organic Additives and Antibiotics in Enhancing Meat Quality and Production Performance of Broiler Chickens

This study aims to compare the effectiveness of commercially available Biofactor (BF) water additives and antibiotics (AB) such as Florfenicol, Neomycin sulfate (30.76%), Tylosin, and Enrofloxacin compared to the control group. During the Experimental Periods, the present study investigates a significant increase in the BF group in total Live Body weight (LBW) with 2057.00 gm/bird compared with 1896.28 and 1924.28 gm/bird in control and AB groups, respectively. Furthermore, there is a significant increase in carcass weight (CW) in the BF group with 1608.29 gm/bird compared with 1422.67 and 1526.29 gm/bird in the control and AB groups, respectively. Moreover, the feed intake and feed conversion ratio (FCR) was the best in BF group compared with the control and AB groups. Also, A higher effective intramuscular fat (IMF) content was observed in BF group meat than in the control and AB groups. The lightness (L*) value was significantly highest in BF meat than in control and AB meat. The present research indicates that adding BF additives to water is an alternative to using antibiotics to enhance the productive performance and meat quality in -Arbor Acres-broiler chicks.
Stochastic Analysis of Control Systems Subject to Communication and Computation Faults

Control theory allows one to design controllers that are robust to external disturbances, model simplification, and modelling inaccuracy. Researchers have investigated whether the robustness carries on to the controller’s digital implementation, mostly looking at how the controller reacts to either communication or computational problems. Communication problems are typically modelled using random variables (i.e., estimating the probability that a fault will occur during a transmission), while computational problems are modelled using deterministic guarantees on the number of deadlines that the control task has to meet. These fault models allow the engineer to both design robust controllers and assess the controllers’ behaviour in the presence of isolated faults. Despite being very relevant for the real-world implementations of control system, the question of what happens when these faults occur simultaneously does not yet have a proper answer. In this paper, we answer this question in the stochastic setting, using the theory of Markov Jump Linear Systems to provide stability contracts with almost sure guarantees of convergence. For linear time-invariant Markov jump linear systems, mean square stability implies almost sure convergence – a property that is central to our investigation. Our research primarily emphasises the validation of this property for closed-loop systems that are subject to packet losses and computational overruns, potentially occurring simultaneously. We apply our method to two case studies from the recent literature and show their robustness to a comprehensive set of faults. We employ closed-loop system simulations to empirically derive performance metrics that elucidate the quality of the controller implementation, such as the system settling time and the integral absolute error.
Cerasome Versus Liposome: A Comparative Pharmacokinetic Analysis Following Intravenous Administration into Rats

Background Cerasomes, due to their external siloxane network, demonstrate markedly higher physicochemical stability and, therefore, easier handling and storage than liposomes. Objectives The main objective of this study was to compare the pharmacokinetics (PK) of cerasome and liposome following intravenous administration. The PK of PEGylated and non-PEGylated cerasomes was also compared to see whether the presence of a hydrophilic siloxane network on the surface of cerasomes can play the role of polyethylene glycol (PEG) in increasing the blood circulation of these vesicles. Methods Silver sulfide (Ag2S) quantum dots (Qds)-loaded PEGylated and non-PEGylated cerasomes and PEGylated liposomes were fabricated and thoroughly characterized in terms of particle size, polydispersity index, zeta potential, entrapment efficiency, and in vitro stability. For pharmacokinetic evaluation, the free Qds and the selected formulations were intravenously injected into rats, and blood samples were collected for up to 72 hours. Pharmacokinetic parameters were calculated by the non-compartmental method. Results Both cerasomal and liposomal carriers significantly improved the PK of Qds. For example, the elimination half-life (t1/2) and the area under the plasma concentration-time curve from time 0 to time infinity (AUC0-∞) for the free Qds were 4.39 h and 8.01 µg/mL*h and for cerasomal and liposomal formulations were 28.82 versus 26.95 h and 73.25 versus 62.02 µg/mL*h, respectively. However, compared to each other, the plasma concentration-time profiles of PEGylated cerasomes and liposomes displayed similar patterns, and the statistical comparison of their pharmacokinetic parameters did not show any significant difference between the two types of carriers. For PEGylated cerasomes, t1/2 and AUC0-∞ values were respectively 1.6 and 3.3 times greater than the classic cerasome, indicating that despite the presence of a hydrophilic siloxane network, the incorporation of PEG is necessary to reduce the clearance of cerasomes. Conclusions The comparable PK of PEGylated cerasomes and liposomes, along with the higher physicochemical stability of cerasomes, can be considered an important advantage for the clinical application of cerasomes. Additionally, the easy surface functionalizing ability of cerasomes confers a dual advantage over liposomes. The study findings also showed that the presence of a hydrophilic siloxane network on the surface of cerasomes alone is not enough to make them circulate long.
Relationship Between Workplace Incivility, Employee Performance And Employee Engagement In Healthcare Institutions

Workplace incivility is a well-known problem that affects every firm and its environment. Employee engagement may result in physical and mental suffering, impacting how well people perform. The study aims to ascertain the relationship between employee engagement, employee performance, and workplace incivility. For this, scales of the investigated variables were used to build a well-structured questionnaire. The survey questionnaire was sent out to workers and employees of Health Care Institutions. There were 212 valid responses in total. SEM, or structural equation modelling, was utilized to establish relationships. The study's findings rejected hypotheses H1 and H2 showing workplace incivility (WPI) has a detrimental effect on employee engagement (EENG) at ( β= - 0.34, P >.05) and employee performance (EP) at (β = -0.27, P >.05). While adopting the hypothesis H3, employee engagement had a favourable impact on the performance of employees at (β = 0.36 P 0.05).
Versatile strategies for adult neurogenesis: avenues to repair the injured brain

Brain injuries due to trauma or stroke are major causes of adult death and disability. Unfortunately, few interventions are effective for post-injury repair of brain tissue. After a long debate on whether endogenous neurogenesis actually happens in the adult human brain, there is now substantial evidence to support its occurrence. Although neurogenesis is usually significantly stimulated by injury, the reparative potential of endogenous differentiation from neural stem/progenitor cells is usually insufficient. Alternatively, exogenous stem cell transplantation has shown promising results in animal models, but limitations such as poor long-term survival and inefficient neuronal differentiation make it still challenging for clinical use. Recently, a high focus was placed on glia-to-neuron conversion under single-factor regulation. Despite some inspiring results, the validity of this strategy is still controversial. In this review, we summarize historical findings and recent advances on neurogenesis strategies for neurorepair after brain injury. We also discuss their advantages and drawbacks, as to provide a comprehensive account of their potentials for further studies.
Toward Detection and Attribute of Cyber - Attacks in IoT - Enabled Cyber-Physical Systems

: Securing Internet-of-Things (IoT)-enabled cyber– physical systems (CPS) can be challenging, as security solutions developed for general information/operational technology (IT/OT) systems may not be as effective in a CPS setting. Thus, this article presents a two-level ensemble attack detection and attribution framework designed for CPS, and more specifically in an industrial control system (ICS). At the first level, a decision tree combined with a novel ensemble deep representation-learning model is developed for detecting attacks imbalanced ICS environments. At the second level, an ensemble deep neural network is designed to facilitate attack attribution. The proposed model is evaluated using real-world data sets in gas pipeline and water treatment system. Findings demonstrate that the proposed model outperforms other competing approaches with similar computational complexity.
Consideraciones en la intervención psicopedagógica en el alumnado universitario con discapacidad

espanolEn este articulo se tratan aspectos de la situacion educativa universitaria del alumnado con discapacidad. En el se busca situar elementos de intervencion psicopedagogica, a traves de la actuacion llevada a cabo por un Servicio de Apoyo al Alumnado con discapacidad. Con todo se pretende en ultima instancia, favorecer la reflexion sobre el papel de la Orientacion Educativa, el Profesorado y la Comunidad Universitaria en general, en su relacion con la discapacidad. EnglishIn this article is treated aspects about university education situation of pupils with disability. Has been treated we want to place elements for Psychopedagogic intervention, will the help offered by the Support Service's for there particular pupils. Our aim is to help the reflexion about Educational Guidance, the Teaching staff and the University Community, in general terms, in relation to disability.
A Rare Case of Gastrointestinal Stromal Tumor of the Abdominal Cavity: A Case Report

Gastrointestinal stromal tumors (GISTs) are rare gastrointestinal neoplasms. We are presenting a 57-year-old female patient with a GIST of considerable dimensions that was deemed unresectable during the initial intervention. The patient had a previous surgical record of a peritoneal sarcomatosis tumor that covered approximately 50% of the abdominal cavity. The patient underwent surgical procedures, including exploratory laparotomy, lumpectomy, splenectomy, proximal gastrectomy, esophagogastric anastomosis, pyloroplasty, jejunostomy, and left diaphragm plasty. One of the observed results was the presence of a 50×40 cm exophytic multilobed cerebroid-like tumor in the abdomen region, specifically dependent on the gastric fundus. The primary treatment for patients without metastases is surgical removal of the tumor, with wedge resection being recommended for the preservation of organ function and quality of life postoperatively.
CITIES AND AUTOMOBILE DEPENDENCE: AN INTERNATIONAL SOURCEBOOK

The book provides data on a uniform, standardized basis for major cities of the world, bringing together transport patterns and land use to provide insight into the question of automobile dependency. The basic contention of the book is the need to reassert the importance of those who plan transport infrastructure and land use in cities as a way of addressing the central question of how to make a city less dependent on the automobile. The methodology used is examined to ensure data were defined properly and are comparable on an international basis. Main findings are presented, as are other factors affecting gasoline and car use patterns. Finally, analysis is provided for a series of major policy areas for reducing automobile dependence which appear to develop from the data obtained.
The Impact of Hispanic Last Names and Identity on Labor Market Outcomes

In this paper, I study discrimination against Hispanics in the labor market. I compare the children of inter-ethnic marriages to study the impact of having a Hispanic last name. While males born to Hispanic father-White mothers earn 6 percentage points less than those born to White father-Hispanic mothers, the gap could be completely explained by educational differences. I also study the effect of identifying as Hispanic on earnings. I find that men with a Spanish-sounding last name who identify as Hispanic earn significantly less than those who do not identify as Hispanic, but the gap could also be explained by educational differences
Climate-smart agriculture: smallholder adoption and implications for climate change adaptation and mitigation

v 1. Overall context: climate change and agricultural households 1 2. Overview of costs and barriers to adopting climate smart sustainable land management practices and investments 3 3. Household-level agricultural practices and investments: adaptation and mitigation 5 3.1 Agroforestry 5 3.2 Soil and water conservation 7 3.2. 1 Conservation agriculture (CA) 7 3.2. 2 Cropping patterns: cover crops, intercrops, improved fallows and alley crops 9 3.2. 3 Soil and water conservation structures/investments 11 3.3 Grazing land management 12 4. Project-based evidence on cost barriers to climate smart sustainable land management adoption 15 5. Concluding observations 18
Mechanism and Role of Tumor Microenvironment in the Initiation and Progression of Bladder Cancer

Tumor microenvironment (TME) is a huge network, composed by tumor cells, tumor associated stromal cells, immune cells, cytokines and chemokines secreted by these cells, in which various cells communicate with each other. Bladder cancer is characterized of tendency of relapse, progression, metastasis because of the role of TME. With the application and development of new technologies recently, such as tumor bulk RNA-sequencing and single-cell transcriptome sequencing, the composition of TME for bladder cancer is increasingly clear and the complex cell-to-cell communication network is fully duged, which provides a new vision for the therapy of bladder cancer. This paper reviewed and further analysed the research hotspots of cellular components and extracellular matrix components of bladder cancer on the basis of the latest research progress.
Performance measurement systems in the health and care sector: Are targets and monitoring additional demands or resources for employees?

PurposeThis paper aims to improve our understanding of performance measurement systems in the health and care sector, by focussing on employee reactions to core performance measurement practices. Targets and monitoring are hypothesised to be associated with employee perceptions of job control, supportive management and job demands, which in turn, are expected to be linked to employee-wellbeing and organisational commitment.Design/methodology/approachMatched employee workplace data are extracted from a nationally representative and publicly available survey. Structural equation models are estimated.FindingsPerformance measurement systems are neither perceived as resources nor additional demands. Setting many targets and a focus on productivity can lead to negative employee outcomes, since these positively correlate with perceptions of job demands, which negatively correlate with employee wellbeing. However, monitoring financial performance and monitoring employee performance may be helpful to managers, as these are positively associated with employee perceptions of job control and supportive management, which positively correlate with job satisfaction and organisational commitment and, negatively, with anxiety. Overall, common criticisms of performance measurement systems in healthcare are questioned.Originality/valueGiven the lack of consensus on how performance measurement systems can influence employee experiences and outcomes, this study combines theories that argue for performance measurement systems in managing operations with models developed by psychologists to describe how perceptions of the work conditions can affect employee attitude and wellbeing. A conceptual model is therefore developed and tested, and potential direct and indirect effects of performance measurement systems in the health sector are inferred.
Enrichment of Daphnia magna (Straus, 1820) with Viterna and Its Effects on the Growth and Survival Performance of the Freshwater Angelfish Pterophyllum scalare (Schultze, 1823) Larvae

1 Department of Aquaculture, Faculty of Agriculture, Universitas Lampung, Bandar Lampung, Lampung, 35145, Indonesia 2 Program Study of Aquaculture, Faculty of Agriculture, Universitas Lampung, Bandar Lampung, Lampung, 35145, Indonesia 3 Department of Aquaculture, Faculty of Fisheries and Marine, Universitas Airlangga, Surabaya, East Java, 60115, Indonesia 4 Department of Aquaculture, Faculty of Fisheries and Marine, Universitas Airlangga, Surabaya, Indonesia Department of Marine Biology, Faculty of Marine Sciences, King Abdulaziz University, Jeddah, 21589, Kingdom of Saudi Arabia 5 Program Study of Aquaculture, Faculty of Fisheries and Marine, Universitas Airlangga, Surabaya, East Java, 60115, Indonesia Corresponding Author: idahasan64@gmail.com
Role of MicroRNAs in Alcohol-Related Liver Disease

ABSTRACT Alcohol-related liver disease (ARLD) is the most prevalent type of chronic liver disease and one of the most serious health problems worldwide. Individuals consuming more than 40 g of alcohol per day can develop alcoholic fatty liver (AFL). Progression of AFL to alcoholic steatohepatitis leading to ARLD. The risk factors such as oxidative stress, inflammatory response, and genetic and epigenetic factors might explain considerable variation in ARLD pathogenesis. Diagnosis of patients with ARLD involved assessing alcohol use disorder and signs of advanced liver disease. Increasing number of patients with advanced stages of ARLD is observed due to failure in early detection and treatment. Alcohol abstinence, nutritional therapy and corticosteroids are the best treatment for all stages of ARLD. Therapies targeting IL-22/STAT3, TNF receptor superfamily, antioxidant signal, LPS, inflammasomes, hormones and microRNAs are used in treatment of ARLD as translational research. MicroRNAs are non-coding RNAs mainly involved in underlying mechanisms of development and pathogenesis of ARLD. The current review summarizes the role of aberrant regulation of microRNAs involved during oxidative stress, epigenetic modulations and inflammatory response in ARLD and also focused on the underlying mechanism of microRNAs in different stages of liver diseases such as liver fibrosis, liver cirrhosis and hepatocellular carcinoma.