Miracle-dz/UniFAR-FTUs huggingface dataset:
PEMBENTUKAN DAN KARAKTERISASI FISIKA KIMIA KO-KRISTAL PIROXICAM-ASAM TARTRAT-SAKARIN DENGAN METODE SOLVENT DROP GRINDING

Piroxicam is an enolic acid derivative (oxicam) as a non-steroidal anti-inflammatory drug (NSAID). Piroxicam is used to reduce or eliminate the risk of rheumatoid arthritis and osteoarthritis. Piroxicam is categorized as BCS (Biopharmaceutical Classification System) class II, which has low solubility and high permeability. The purpose of this study was to increase the solubility of co-crystal modified piroxicam in the solubility test and to characterize the physical and chemical properties of piroxicam co-crystal including Fourier Transform Infra Red (FTIR), Differential Scanning Calorimetry (DSC) test, X-Ray test. Diffraction (XRD), flow properties test and incompressible density test. Formation of co-crystals using the Solvent Drop Grinding method by grinding together piroxicam, tartaric acid, saccharin for 15 minutes, then adding a little methanol solvent and stored in a desiccator. The co-crystals formed were tested for their physicochemical characterization. The results of the analysis showed that the co-crystal piroxicam tartaric acid-saccharin molar ratio of 1:1:1 in 0.1 N HCl solvent had a higher solubility than pure piroxicam and co-crystals of piroxicam tartaric acid-saccharin molar ratio of 2:1:1. The results of the co-crystal analysis of formula 1 (1:1:1) in the FTIR test showed the absorption wavelength of the C=O group was 1736.73 cm -1 , the XRD test results experienced a decrease in the intensity of the diffraction peaks at angles of 8, 14, 17 and 27 o namely 1431.23, 1081.58, 1726.28 and 1228.92 cts. The results of the DSC test decreased the melting point of 163.90 o C and the enthalpy energy decreased by 53.97J/g. The average compressibility index test results were 10.8%, the average solubility test results for piroxicam in 0.1 N HCl solvent was 59.10 mg/mL.
Malnutrition in all its forms and social inequalities in Brazil

Abstract Objective: To describe malnutrition (undernutrition and excess weight) by income, education and race/ethnicity in the Brazilian population. Design: Cross-sectional study. Setting: Brazil. Participants: Children aged <5 years (n 14 580), adolescents aged 11–19 years (n 31 892) and adults aged 20–49 years (n 84 660). Results: Among children, prevalence of excess weight, wasting and stunting was 16·9, 2·8 and 6·0 %, respectively. Differences related to income, education and race/ethnicity were verified, except for prevalence of wasting by education level. Girls and boys presented 18·4 and 20·5 % of excess weight, 2·8 and 3·7 % of underweight and 5·5 and 7·3 % of stunting, respectively. Prevalence of excess weight was lower among poorer, lower-educated (only for boys) and white adolescents, while stunting was lower among higher-income, higher-educated and white adolescents. Over three-quarters of women and almost half of men presented excess weight. Among adults, 3·9 % of women and 1·7 % of men were underweight, and 5·7 % of women and 0·2 % of men presented short stature. Prevalence of excess weight for women was higher among lower education and black, while for men it was higher among higher income and education and white. Short stature was more prevalent among black and mixed-race, low-educated and low-income women. Underweight prevalence was higher among low-educated, black and mixed-race women. Conclusions: In Brazil, the prevalence of excess weight was at least threefold higher than that of undernutrition for children and adolescents and at least sevenfold higher for adults. Social inequalities were observed in the distribution of malnutrition across the lifespan and by gender.
Wildlife Deterrence from Hazards Using High Brightness Ultraviolet Light

The purpose of this study was to examine the behavioral impact of varying LED (light emitting diode) spectral emissions on avian species. A novel oculo-neuro-motor response to monochromatic LEDs has been identified. LED colored light of sufficient intensity matched to the short-wavelength cones of avian species can efficiently diminish overall visual perception leading to an augmented behavioral response. The study method involved monitoring the change in behavioral response after exposure to high brightness monochromatic LED light to wild Osprey (Pandion haliaetus) foraging and nesting in their natural environment. Our results demonstrated a statistically significant change in foraging behaviors with wild Osprey (p = 0.005) and in nesting behavior as a result of exposure to high brightness monochromatic LED light. An augmented behavioral responses was observed which is believed to be analogous to human reaction to solar glare and glint. The neuroimaging mechanism of avian species is discussed. This novel augmented behavioral response provides a new technique of studying the neuroscience of temporal and spatial light stimulus. A non-lethal deterrence technique involving the augmented behavioral response could mitigate mortality and morbidity of avian-human conflict in areas such as airports, airplane bird strikes, and wind turbines.
The Effectiveness of Co-Inoculation by Consortia of Microorganisms Depends on the Type of Plant and the Soil Microbiome

The amalgamation of mineral and targeted bacterial preparations represents a new generation of agricultural technology. Inoculation with combined preparations of microorganisms is more effective than inoculation with a single microorganism in stimulating plant growth by providing a more balanced diet for various crops. In this work, the effect of inoculation of 20 consortium variants on the yield indicators of three crops (wheat, buckwheat, corn) and the soil microbiome in the open field was investigated. The soil microbiome was defined by 16S rRNA sequences through NGS. The species richness of the soil microbial community (alpha diversity) was similar for all studied samples. A beta-diversity analysis revealed that the microbial diversity of three soil samples (C.bw, F.bw and Soil.bw) differed significantly from all others. At the phylum level, the number of Acidobacteriota and Firmicutes in these samples was increased. For the combination “Consortium C (Rothia endophytic GMG9 and Azotobacter chroococcum GMG39)—buckwheat”, a systemic positive improvement in all growth and yield indicators was observed. The soil of the site where buckwheat grew, inoculated by Consortium C, contained significantly more available phosphorus than all other soil samples. Such results can be explained both by the direct action of a consortium of phosphate-immobilizing and nitrogen-fixing bacteria and acidification of the medium due to an increase in phylum Acidobacteriota bacteria in the soil.
Synthesis of CdSe Quantum Dots in Two Solvents of Different Boiling Points for Polymer Optical Fiber Technology

Polymer materials find many applications in various industries. Efforts are being made to obtain structures with increasingly better properties. It is necessary not only to obtain new materials but also to modify existing structures. Such is the situation with polymer optical fibers. The widespread use of polymer optical fibers is impossible, due to their very high optical losses compared to glass optical fibers. The solution to this problem can be the manufacturing of polymer active optical fibers. Active fibers are the basic components of fiber optic amplifiers and lasers that allow the direct amplification of light inside the fiber. In order for their operation to be the most effective, it is necessary to use dopants. The most commonly used are lanthanide ions isolated from the polymer network, active organic dyes, and quantum dots. These dopants are characterized by very high luminescence and long glow times. Quantum dots of CdSe are made using two organic solvents that differ in boiling points—hexane (a low-boiling solvent with a boiling point of 69 °C) and 1-octadecene (a high-boiling solvent with a boiling point of 315 °C). This work aims to test whether the type of solvent used to obtain quantum dots affects the doping capabilities of polymer structures, from which optical fibers can then be drawn.
Consumo cultural em tempos de convergência: uma análise dos jovens sergipanos

The research aimed to discuss the cultural consumption practices in the Northeast considering the intervention of media convergence at the reception of the contents. Therefore, we sought to carry out a comparative analysis of responses to a questionnaire applied to young Sergipeans, the capital and the interior. The focus of the focused approach particularities resulting from the scenario in which this audience interacts and the offer of cultural products, in a context in which we see large differences in the human development index (HDI) of municipalities in the capital and the countryside, which can take place in conditions of access to different means. In conclusion, we realize that with the advancement in the use of technological devices and access digital social networks young people, while consuming media content, also serve as producers to share the information with their network. However, while they all have access to digital technologies, the production of content for this audience is still based on local cultural offerings, from the cities of Sergipe. Keywords: cultural consumption, media convergence, media reception, young.
Effects of Fusarium culmorum infection on protein quality and baking properties of wheat (Triticum aestivum L.)

Fuzarijska palež klasa je s ekonomskog aspekta jedna od najstetnijih gljivicnih bolesti psenice. Mikotoksini producirani Fusarium vrstama predstavljaju zdravstveni rizik za ljude i životinje. U radu je analizirano 14 kultivara psenice razlicite pecivne kakvoce i otpornosti na Fusarium vrste. Uzorci psenice su prikupljeni na Poljoprivrednom institutu Osijek tijekom 2008/2009 i 2009/2010. Istraživanje je provedeno s ciljem utvrđivanja jacine utjecaja umjetne zaraze Fusarium culmorumom na kakvocu rezervnih bjelancevina i pecivna svojstva psenice. U radu su analizirani parametri kakvoce zrna, brasna i tijesta. Provedeno je probno pecenje kruha i analizirana je kolicina deoksinivalenola (DON) u brasnu. RP-HPLC metodom su analizirane rezervne bjelancevine psenice. Umjetna zaraza Fusariumom nije statisticki znacajno utjecala na kolicinu ukupnih bjelancevina i vlažnog glutena. Fusarium zaraza je imala stetan utjecaj na konzistenciju i otpor tijesta na rastezanje kao i na izgled i oblik kruha. Stupanj utjecaja Fusariuma na svojstva kakvoce psenice je znacajno uvjetovan sortom. U umjetno zaraženim uzorcima je kolicina albumina i globulina, ukupnih glutenina i njihovih HMW and LMW podjedinica znacajno smanjena, dok se kolicine ukupnih, - i - glijadina nije znacajno mijenjala.
Lassa fever and infection control: Knowledge, attitudes and practice in a University Teaching Hospital in Uyo, Nigeria

Context: Lassa fever is a deadly viral hemorrhagic disease that is endemic in Nigeria with recurrent outbreaks that often affect healthcare workers. Hospital infection control can potentially limit the impact of outbreaks of this disease in healthcare settingsObjective: To determine the knowledge attitudes and practices toward Lassa fever and infection control among medical doctors and students in Uyo, Nigeria.Methods: This was a cross sectional survey of knowledge attitude and practice among medical students, house officers and resident doctors undergoing training in the University of Uyo Teaching Hospital using a 23-point structured self-administered questionnaire.Results: 89.5% of participants correctly identified the causative agent for Lassa fever to be a virus. 141 participants correctly identified rats as the reservoir for Lassa fever. The state chosen by most participants to have the highest prevalence of Lassa fever was Edo State (44.8%), followed by Adamawa State (20.4%). 79.7% of participants correctly identified the drug treatment of Lassa fever. Most participants agreed that there is a possibility of contracting Lassa fever in the course of their duties and that facilities in the hospital are not sufficient to protect them from contracting the infection.Conclusion and recommendations: There is good knowledge of Lassa fever among medical trainees but with significant gaps. There is need to place more emphasis on Lassa fever and infection control in training curricula.
Indoor biological exposures : what can HVAC filter dust tell us?

Because people in the US spend an estimated 80-90% of their time indoors, much of it at home, understanding the potential health impacts of biological exposures that occur in the home is crucial. Recently, rapid advances in high-throughput DNA sequencing technology have spurred increased study of the relationships between the human and built environment microbiomes. HVAC filters hold promise as long-term, spatially integrated, high volume samplers to characterize the airborne home microbiome. In order to optimize HVAC sampling protocols and improve comparability between studies employing HVAC filters for bacterial community analysis, three HVAC filter dust sampling methods were compared. These three methods, vacuuming the filter surface, swabbing the filter surface, and eluting filter dust in a buffer, were selected as representative of previously published methods. Our findings suggest that vacuum and swab samples produced more repeatable and representative bacterial communities than did elution. Furthermore, given the reduced labor and cost of vacuum and swab methods, and the additional advantage that these two methods may also be applied to sampling dust
Laparoscopic Sleeve Gastrectomy with Roux en-Y Bypass (A Novel Modification) for Morbid Obesity: A Prospective Observational Study

Background Recently, obesity witnessed a dramatic increase and its related comorbidities have grown. Bariatric surgeries were developed to reduce weight. However, all techniques had their advantages and shortages. In this work, we aimed to assess our new modification of combining sleeve gastrectomy with Roux en-y bypass for the management of obesity, hoping to gain benefits from both techniques to increase the excess bodyweight loss (EBW%). Methods The study was a prospective observational study on 23 Morbidly obese patients. The study was held from January 2020 to April 2022. The recruited patients were submitted to detailed clinical assessment and investigations to check fitness for surgery. Besides operative data, any intra- or post-operative complications were recorded. Each patient was followed up for at least one year. The follow-up visits were scheduled at regular intervals (one week, one month, six months, and twelve months). Results The mean operative time was 113.91 minutes (65-150). No intraoperative complications or conversion. There was intraluminal bleeding in one patient within 48 hours postoperatively with successful conservative management. There was a complete cure of diabetes mellitus (DM) for 5, 2, and 3 patients and antidiabetic drugs were reduced for 64.3%, 21.43%, and 7.14% at 1, 6, and 12 months follow up respectively. Hypertension was cured in 1,1,2 patients, and antihypertensives were reduced for 2,1,1 patient, at 1, 6, and 12 months follow up respectively. EWL% was 14.4%, 40.78%, and 73.74% at 1,6,12 months follow up respectively. Hemoglobin concentration and ionized calcium improved over time. Finally, serum albumin at 1, 6, and 12 months follow-up was 3.64, 3.58, 3.78 g/dL respectively. Conclusion New modifications of combining LSG and LRYGB have shown to be safe and effective procedures. In addition, it is associated with minimal postoperative nutritional complications and permits complete visualization of the biliary system using endoscopy.
Impact of Dietary Regime and Seasonality on Hindgut’s Mycobiota Diversity in Dairy Cows

We describe and discuss the intestinal mycobiota of dairy cows reared in France following variations in dietary regimes and two seasons. Two groups of 21 animals were followed over a summer and winter period, and another group of 28 animals was followed only during the same summer season. The summer diet was based on grazing supplemented with 3–5 kg/d of maize, grass silage and hay, while the winter diet consisted of 30% maize silage, 25% grass silage, 15% hay and 30% concentrate. A total of 69 DNA samples were extracted from the feces of these cows. Amplification and sequencing of the ITS2 region were used to assess mycobiota diversity. Analyses of alpha and beta diversity were performed and compared statistically. The mycobiota changed significantly from summer to winter conditions with a decrease in its diversity, richness and evenness parameters, while beta diversity analysis showed different mycobiota profiles. Of note, the Geotrichum operational taxonomic unit (OTU) was prevalent in the winter group, with a mean relative abundance (RA) of 65% of the total mycobiota. This Geotrichum OTU was also found in the summer group, but to a lesser extent (5%). In conclusion, a summer grazing diet allowed a higher fecal fungal diversity. These data show, for the first time, that a change in diet associated with seasonality plays a central role in shaping hindgut fungal diversity.
Isolasi dan Identifikasi Jamur Patogen pada Air Sumur dan Air Sungai di Pemukiman Warga Desa Karangwangi, Cianjur, Jawa Barat

Abstrak. Penelitian Isolasi dan Identifikasi Jamur Patogen pada Air Sumur di Wilayah Pemukiman Warga RW 05-08 dan Air Sungai Cilaki, Desa Karangwangi, Cianjur, Jawa Barat, bertujuan untuk melihat keanekaragaman jamur patogen yang terdapat pada air sumur RW 05-08 dan air sungai Cilaki. Metode yang digunakan dalam penelitian ini adalah metode deskriptif eksploratif untuk menentukan lokasi pengambilan sampel. Dilakukan pengenceran dari sampel air kemudian dilakukan metode pour plate dengan medium Agar Sabouraud lalu diinkubasi selama 72-96 jam. Koloni jamur dihitung dengan metode Total Plate Count (TPC). Identifikasi dilakukan secara makroskopis dengan melihat bentuk dan warna koloni jamur, serta secara mikroskopis dengan cara moist chamber. Hasil jumlah koloni jamur patogen terbanyak ditemukan pada sumur RW 06. Hasil penanaman seluruh sampel air sumur dan sungai, ditemukan 9 spesies jamur patogen, genus Penicillium sebanyak 2 spesies, Trichophyton sebanyak 3 spesies, Geotrichum sebanyak 2 spesies, Microsporum dan Lichtheimia masing-masing sebanyak 1 spesies. Dari hasil yang didapat, disimpulkan bahwa air sumur di wilayah RW 05-08 dan air sungai Cilaki di Desa Karangwangi kurang baik jika digunakan secara langsung karena banyaknya jamur patogen yang terkandung di dalamnya. Kata Kunci: Jamur, Sumur, Sungai, Total Plate Count. Abstract. Isolation and Identification of Pathogenic Fungi on Well Water Territory Residential Residents RW 05-08 and Cilaki River Water, Karangwangi village, Cianjur, West Java research, aiming to see the diversity of fungal pathogens found in well water RW 05-08 and Cilaki river water. The method used in this study is descriptive exploratory method for determining the location of sampling of water in wells in RW 05 to RW 08 and Cilaki river. Do dilution of water samples and then performed pour plate method with Sabouraud agar medium and incubated for 72-96 hours. Fungal colonies which have grown calculated by the method Total Plate Count (TPC). Identification is done macroscopically by looking at the shape and color of fungal colonies and microscopically by creating a wet media room (moist chamber). The result is the highest number of colonies of pathogenic fungi found in well water samples RW 06. From the planting around the wells and river water samples, found as many as nine species of fungal pathogens, with as many as two species of the genus Penicillium, Trichophyton many as three species, Geotrichum much as 2 species , Microsporum and Lichtheimia each as much as one species. From the results obtained, it can be concluded that water wells in the area RW 05-08 and Cilaki river water in Karangwangi village less well if used directly because of the large number of pathogenic fungi colonies contained there in. Keywords : Pathogenic Fungi, Water, Well, River, Pour Plate, Total Plate Count, Moist Chamber
Teplizumab: The Newest Weapon in the Fight against Type 1 Diabetes

Teplizumab, a monoclonal antibody used for the prevention and treatment of type 1 diabetes, is the result of significant contributions from various scientists and researchers. This review explores the scientists' contributions and provides an overview of the drug's history and discovery. Teplizumab represents a significant advancement in the treatment of type-1 diabetes and holds promise for other autoimmune diseases. Its physicochemical properties, synthesis methods, therapeutic uses, and potential adverse effects contribute to its overall effectiveness and safety. Ongoing research and development aim to further enhance teplizumab's efficacy and convenience for patients.
Identifikasi Penjalaran Gelombang Panjang Samudera Hindia Ke Selat Lombok Berdasarkan Komponen Harmonik Arus

The Lombok Strait is one area passing by seawater mass from Pacific Ocean to Indian Ocean, well known as Indonesia Through Flow (ARLINDO). It was profen by the existane of long periode harmonic current component affected by the sun (SA, SSA ) , and an influence by moon (MSF). The harmonic current speed has an average of 0.370668 m/s in the depths of 100 meters during January 9, 2004 until 14 June 2005 (1.5 years). Time series data ocean current of INSTANT project (2004-2005) is used in this research, analized by using toolbox module of t-tide 1.3 beta. The current rose at 350 meters deep and 450 meters deep shous pattern of the a unique ocean current, which mastly toward to north and northeast (55 %) with velocity at 0.2-1.0 m/s. The current is coming from Indian Ocean which proven by the existence of components like M4, MS4, MSF, O1. There is also ocean current toward to south and southwest as (45 %) with speed of 0.11-0.9 m/s. Thie ocean current which coming from Indian Ocean is indication of propagation of long wave penetration to Lombok Strait. During its propagation passing the sill, the wave become an internal wave in Lombok Strait. Keywords : internal wave, indian ocean, lombok strait, harmonic currents component, INSTANT 2004-2005
The Gender Differential Analysis: Knowledge, Attitude, Practices and Aspirations of Pesticide Use Among Cocoa Farmers In Asamankese Cocoa District, Ghana

Attempts to attain flawless agricultural production are still hampered by a range of restrictive factors including water scarcity, climate change, plant pests and diseases. Worries about the negative and unpleasant repercussions of pesticides on health are evolving in developing countries including Ghana. Cocoa farmers’ knowledge awareness, attitude, practices and skills in handling pesticides and the potential hazards it poses to them are vital in preventing pesticide exposure and hazards. This study examines the knowledge, attitudes, practices and aspiration of cocoa farmers in Ghana regarding pesticide use and the potential hazards it poses to their health. The paper highlights the importance of understanding the diverse roles and perspectives of male and female farmers in agricultural production. The study uses a quantitative approach and a cross-sectional descriptive approach to analyze data from 364 cocoa farmers in the Asamankese Cocoa District. The study found that both male and female cocoa farmers have a positive attitude towards pesticide usage, and their knowledge of pesticide handling practices is adequate. The study also found that male and female farmers have different levels of knowledge, attitudes, and practices regarding pesticide use. The findings suggest that there is a need for increased awareness and education on safe pesticide handling practices to prevent pesticide exposure and its negative health effects on farmers.