Miracle-dz/UniFAR-FTUs huggingface dataset:
Speedup of Implementing Fuzzy Neural Networks With High-Dimensional Inputs Through Parallel Processing on Graphic Processing Units

This paper proposes the implementation of a zero-order Takagi-Sugeno-Kang (TSK)-type fuzzy neural network (FNN) on graphic processing units (GPUs) to reduce training time. The software platform that this study uses is the compute unified device architecture (CUDA). The implemented FNN uses structure and parameter learning in a self-constructing neural fuzzy inference network because of its admirable learning performance. FNN training is conventionally implemented on a single-threaded CPU, where each input variable and fuzzy rule is serially processed. This type of training is time consuming, especially for a high-dimensional FNN that consists of a large number of rules. The GPU is capable of running a large number of threads in parallel. In a GPU-implemented FNN (GPU-FNN), blocks of threads are partitioned according to parallel and independent properties of fuzzy rules. Large sets of input data are mapped to parallel threads in each block. For memory management, this research suitably divides the datasets in the GPU-FNN into smaller chunks according to fuzzy rule structures to share on-chip memory among multiple thread processors. This study applies the GPU-FNN to different problems to verify its efficiency. The results show that to train an FNN with GPU implementation achieves a speedup of more than 30 times that of CPU implementation for problems with high-dimensional attributes.
Dependability analysis of Web services

Web Services form the basis of the web based eCommerce eScience applications so it is vital that robust services are developed. Traditional validation and verification techniques are centred around the concept of removing all faults to guarantee correct operation whereas Dependability gives an assessment of how dependably a system can deliver the required functionality by assessing attributes, and by eliminating threats via means attempts to improve dependability. Fault injection is a well-proven dependability assessment method. Although much work has been done in the area of fault injection and distributed systems in general, there appears to have been little research carried out on applying this to middleware systems and Web Services in particular. There are additional problems associated with applying existing fault injection technologies to Web Services running in a virtual machine environment since most are either invasive or work at a machine level. The Fault Injection Technology (FIT) method has been devised to address these problems for middleware systems. The Web Service-Fault Injection Technology (WS-FIT) implementation applies the FIT method, based on network level fault injection, to Web Services to create a non-invasive dependability assessment method. It allows targeted perturbation of Web Service RFC parameters as well as more traditional network level fault injection operations. The WS-FIT tool includes taxonomies that define a system under test, fault models to apply and failure modes to be detected, and uses these taxonomies to generate fault injection campaigns. WS-FIT has been applied to a number of case studies and has successfully demonstrated its effectiveness. It has also been successfully applied to a third-party system to evaluate dependability means. It performed this dependability assessment as well as allowing debugging of the means to be undertaken uncovering unknown faults.
Epigenetic Coactivation of MAGEA6 and CT-GABRA3 Defines Orientation of a Segmental Duplication in the Human X Chromosome

The human genome harbors many duplicated segments, which sometimes show very high sequence identity. This may complicate assignment during genome assembly. One such example is in Xq28, where the arrangement of 2 recently duplicated segments varies between genome assembly versions. The duplicated segments comprise highly similar genes, including MAGEA3 and MAGEA6, which display specific expression in testicular germline cells, and also become aberrantly activated in a variety of tumors. Recently, a new gene was identified, CT-GABRA3, the transcription of which initiates inside the segmental duplication but extends far outside. According to the latest genome annotation, CT- GABRA3 starts near MAGEA3, with which it shares a bidirectional promoter. In an earlier annotation, however, the duplicated segment was positioned in the opposite orientation, and CT-GABRA3 was instead coupled with MAGEA6. To resolve this discrepancy, and based on the contention that genes connected by a bidirectional promoter are almost always co-expressed, we decided to compare the expression profiles of CT-GABRA3, MAGEA3, and MAGEA6. We found that in tumor tissues and cell lines of different origins, the expression of CT-GABRA3 was better correlated with that of MAGEA6. Moreover, in a cellular model of experimental induction with a DNA demethylation agent, activation CT-GABRA3 was associated with that of MAGEA6, but not with that of MAGEA3. Together these results support a connection between CT-GABRA3 and MAGEA6 and illustrate how promoter-sharing genes can be exploited to resolve genome assembly uncertainties.
Low-DoseAspirinTherapy forCardiovascularPrevention Quantification and Consequences of Poor Compliance or Discontinuation

Abstract . 125 1. Literature Search . 126 2. Compliance with Low-Dose ASA Therapy . 127 2.1 Predictors of Poor Compliance . 127 2.1. 1 Patient Characteristics . 127 2.1. 2 Adverse Events . 135 2.2 Consequences of Poor Compliance with or Discontinuation of Low-Dose ASA Therapy . 136 3. Overview of Compliance Issues . 136 4. How Can We Improve Compliance with Low-Dose ASA Therapy? 137 5. Conclusions . 138
On Health-Related Quality of Life and Diagnostic Improvements in Rhinosinusitis Sahlstrand Johnson, Pernilla

Rhinosinusitis is defined as an inflammatory process involving the mucosa of the nose and one or more of the paranasal sinuses. The aims of the work presented in this thesis were to investigate the degree to which rhinosinusitis affects the health-related quality of life (HRQOL), and to determine whether the diagnosis of this condition can be improved using Doppler ultrasound. The HRQOL of 207 patients divided into three subgroups, one with recurrent acute rhinosinusitis, and two with chronic rhinosinusitis, with or without nasal polyps, was evaluated with the 22 Sinonasal Outcome Test (SNOT-22), the 36-item short-form questionnaire (SF-36), the Hospital Anxiety and Depression (HAD) scale and a total visual analogue scale (VAS). These patients’ HRQOL was significantly decreased compared to normative values. Some significant differences in HRQOL scoring were found between the three subgroups. The study cohort reported 8-14 days of absenteeism per year due to their sinus problems. SNOT-22 and the total VAS appeared to be appropriate outcome measures in cases of rhinosinusitis in the Swedish population. It is not possible to differentiate serous sinus fluid (with a low viscosity) from mucopurulent sinus secretions (with high viscosity) with computed tomography (CT) or ultrasound. A means of determining the properties of sinus secretions non-invasively would, however, be of value, as bacteria are often found in mucopurulent secretions in rhinosinusitis. In order to improve the diagnosis of these patients, the ultrasound technique was further developed. In this thesis, it was demonstrated that it is possible to induce acoustic streaming in a sinus model, and that the acoustic properties of a fluid can be determined with Doppler ultrasound. The appropriate frequency of the ultrasound was found to be ~5 MHz. The anatomical dimensions of the maxillary and frontal sinuses were studied on computed tomography images in order to be able to develop a clinically useful Doppler instrument. It was shown how serous sinus fluid can be distinguished from mucopurulent sinus secretion with Doppler ultrasound, without exposing the patient to a harmful increase in temperature.
Accelerated Tooth Movement by Piezocision: A Systematic Review

Background: The demand for esthetic improvement among adult patients is increasing in our society. Currently adult patients seeking orthodontic treatment for either esthetic purposes or functional improvement or both are increasing in number. The drawback of going through orthodontic treatment among adults is the duration of orthodontic treatment that could take up to three years. Surgical adjunctive methods to accelerate orthodontic treatment has been described in literature, however the main issue is the invasive nature of the surgery. Piezocision is a minimally invasive and conservative procedure that is aimed to reduce the duration of treatment and postoperative complications. The aim of this systematic review is to gather updated data in regard to piezocision method for orthodontic treatment. Materials and Methods: Two automated databases (Google Scholar and PubMed using English-language literature) were utilized for this systematic review, operating precise exclusion and inclusion criteria and keywords. The exploration was done in September 2017 and was updated in January 2018. Results: Our inquiry uncovered eight studies that met the exclusion and inclusion criteria. These studies investigated different aspects of accelerated tooth movement, including: new techniques, piezocision method, and updated studies in tooth movement. Conclusions: Piezocision is a minimally invasive and novel method that permits fast orthodontic tooth movement minus the necessity of the traditional extensive surgical method.
Dietary fatty acids and risk factors for coronary heart disease : controlled studies in healthy volunteers

High levels of LDL cholesterol, blood pressure and Lp(a), and low levels of HDL cholesterol increase the risk for coronary heart disease (CHD). This thesis describes the effects of dietary fatty acids on these risk factors. In each of three trials we fed diets with tailored fatty acid composition to about 60 healthy men and women. Each diet within a trial was supplied to every volunteer for 3 weeks.In the first study we compared the effects of monounsaturated trans fatty acids with those of linoleic acid, the fatty acid from which trans fatty acids are formed upon partial hydrogenation, and with those of stearic acid, a product of complete hydrogenation of linoleic acid. Relative to linoleic acid, both trans fatty acids and stearic acid raised LDL and lowered HDL cholesterol. Thus, partial as well as complete hydrogenation of linoleic acid produces fatty acids that unfavorably affect serum lipids relative to linoleic acid itself. Trans fatty acids and stearic acid did not influence blood pressure, but trans fatty acids modestly raised Lp(a). The second study addressed the relative cholesterol-raising potentials of two specific saturates, myristic and palmitic acid. Relative to oleic acid, myristic acid was about 1.5 times as cholesterol-raising a's palmitic acid, due to increases in both LDL and HDL cholesterol. The differences between myristic and palmitic acid were statistically significant. However, both saturates caused high LDL cholesterol levels and raise the LDL to HDL cholesterol ratio.In the third study we examined the effect of the positional distribution of fatty acids within dietary triglycerides. Two diets had identical total fatty acid composition, but a major contrast in fatty acid configuration. Total, LDL, and HDL cholesterol levels were the same on both diets. The position of the dietary fatty acids was partly reflected in fasting plasma lipids, but the fatty acid configuration had no important effect on lipoprotein levels.In conclusion, monounsaturated trans fatty acids and the saturates myristic and palmitic acid have adverse effects on the serum lipoprotein risk profile for CHID. People at high risk for CHD should replace the hard fats in their diets by carbohydrates or unsaturated oils.
The Machine at Work: Technology, Work and Organization

Acknowledgements. Introduction: Deus ex Machina. 1. Theories of Technology. 2. The Luddites: Diablo Ex Machina. 3. Configuring the User: Inventing New Technologies. 4. Some Failures of Nerve in Constructivist and Feminist Analyses of Technology. 5. Technology and Work Organizations. 6. Whata s Social about Being Shot? Notes. References. Index.
Evolution of manipulative microbial behaviors in the rhizosphere

The rhizosphere has been called “one of the most complex ecosystems on earth” because it is a hotspot for interactions among millions of microbial cells. Many of these are microbes are also participating in a dynamic interplay with host plant tissues, signaling pathways, and metabolites. Historically, breeders have employed a plant‐centric perspective when trying to harness the potential of microbiome‐derived benefits to improve productivity and resilience of economically important plants. This is potentially problematic because: (i) the evolution of the microbes themselves is often ignored, and (ii) it assumes that the fitness of interacting plants and microbes is strictly aligned. In contrast, a microbe‐centric perspective recognizes that putatively beneficial microbes are still under selection to increase their own fitness, even if there are costs to the host. This can lead to the evolution of sophisticated, potentially subtle, ways for microbes to manipulate the phenotype of their hosts, as well as other microbes in the rhizosphere. We illustrate this idea with a review of cases where rhizosphere microbes have been demonstrated to directly manipulate host root growth, architecture and exudation, host nutrient uptake systems, and host immunity and defense. We also discuss indirect effects, whereby fitness outcomes for the plant are a consequence of ecological interactions between rhizosphere microbes. If these consequences are positive for the plant, they can potentially be misconstrued as traits that have evolved to promote host growth, even if they are a result of selection for unrelated functions. The ubiquity of both direct microbial manipulation of hosts and context‐dependent, variable indirect effects leads us to argue that an evolutionary perspective on rhizosphere microbial ecology will become increasingly important as we continue to engineer microbial communities for crop production.
The Potential of Self-Assessment and Associated Factors for Delayed Symptomatic Hyponatremia Following Transsphenoidal Surgery: A Single Center Experience

(1) Background: We identified screening parameters and associated factors for delayed, symptomatic hyponatremia (DSH) following inpatient discharge after transsphenoidal surgery (TSS). (2) Methods: In this prospective, monocentric study, 108 patients who underwent TSS for pituitary pathologies were included, provided with a questionnaire and instructed to document urine specific gravity, fluid intake/urine output, body weight and clinical symptoms for every of five days following discharge from hospital. (3) Results: The overall incidence of DSH within 14 days following discharge from the hospital was 14.8% (n = 9). Symptomatic patients presented on average 8.6 days after surgery. Mild DSH was present in 3.3% of the patients, moderate in 1.6% and severe hyponatremia in 9.8% of patients. Female sex (p = 0.02) and lower BMI (p = 0.02), as well as nausea (66.7%; p < 0.01) and emesis (33.3%; p < 0.05), were associated with DSH. A significant weight delta between morning and afternoon weight two days before the event of DSH between both groups (1.26 kg (n = 5) vs. 0.79 kg (n = 52), p < 0.05) was detected. (4) Conclusions: Handing out a symptom questionnaire at discharge seems to be an easy and feasible tool for the detection of DSH after hospital discharge.
VIMOS integral field spectroscopy of blue compact galaxies - I. Morphological properties, diagnostic emission-line ratios, and kinematics

Context. Blue compact galaxies (BCG) are gas-rich, low-luminosity, low-metallicity systems that undergo a violent burst of star formation. These galaxies offer us a unique opportunity to investigate collective star formation and its effects on galaxy evolution in a relatively simple environment. Spatially resolved spectrophotometric studies of BCGs are essential for a better understanding of the role of starburst-driven feedback processes on the kinematical and chemical evolution of low-mass galaxies near and far. Aims. We carry out an integral field spectroscopic study of a sample of BCGs, with the aim of probing the morphology, kinematics, dust extinction, and excitation mechanisms of their warm interstellar medium. Methods. Eight BCGs were observed with the VIMOS integral field unit at the Very Large Telescope using blue and orange grisms in high-resolution mode. At a spatial sampling of 0. 67 per spaxel, we covered about 30 �� × 30 �� on the sky, with a wavelength range of 4150. 7400 A. Emission lines were fitted with a single Gaussian profile to measure their wavelength, flux, and width. From these data we built two-dimensional maps of the continuum and the most prominent emission-lines, as well as diagnostic line ratios, extinction, and kinematic maps. Results. An atlas has been produced with the following: emission-line fluxes and continuum emission; ionization, interstellar extinction, and electron density maps from line ratios; velocity and velocity dispersion fields. From integrated spectroscopy, it includes tables of the extinction corrected line fluxes and equivalent widths, diagnostic-line ratios, physical parameters, and the abundances for the brightest star-forming knots and for the whole galaxy.
E2F3/5/8 serve as potential prognostic biomarkers and new therapeutic direction for human bladder cancer

Objects: Human bladder cancer (BC) is the most common urogenital system malignancy. E2F transcription factors (E2Fs) have been reported to be involved in the growth of various cancers. However, the expression patterns, prognostic value and immune infiltration in the tumor microenvironment of the 8 E2Fs in BC have yet fully to be explored. Methods and strategy: We investigated the differential expression of E2Fs in BC patients, the prognostic value and correlation with immune infiltration by analyzing a range of databases. Results: We found that the mRNA expression levels of E2F1/2/3/4/5/7/8 were significantly higher in BC patients than that of control tissues. And the increased mRNA expression levels of all E2Fs were associated with tumor stage of BC. The survival analysis revealed that the elevated mRNA expression levels of E2F3/5/8 were significantly correlated with the overall survival (OS) of BC patients. And the genetic changes of E2Fs in BC patients were associated with shorter overall survival (OS) and progression-free survival (PFS). In addition, we revealed that the E2F3/5/8 expressions were closely correlated with tumor-infiltrating lymphocytes (TILs). Conclusions: E2F3/5/8 might serve as promising prognostic biomarkers and new therapeutic direction for BC patients.
Double Trouble in Double Descent: Bias and Variance(s) in the Lazy Regime

2 Statement of the Main Result 3 2.1 Assumptions . 3 2.2 Results . 4 2.3 Explicit expression of S, S, S . 5 2.4 Explicit expression of PΨ1 , P v Ψ2 , P v Ψ3 , P e Ψ2 , P e Ψ3 , P d Ψ2 . 5
Biological studies of matrix metalloproteinase sensitive drug delivery systems

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Bounds-Checking Entire Programs without Recompiling [ Extended

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Supplementary Figures and Tables

2. Supplementary Figures 2 2.1 Sample data set analysis in absence of interaction factors. 3 2.2 Calculations with interaction factors . 5 2.3 Sample+ data set analysis with interaction factors. 6 2.4 Common target perturbation in Sample+ data set. 8 2.5 Runtime Analysis . 11
Gastrointestinal delivery of baculovirus displaying influenza 1 hemagglutinin protects mice against heterologous H 5 N 1 infection

25 Main text word count: 4240 26 27 28 29 30 31 32 33 34 35 *Corresponding author. Mailing address: Animal Health Biotechnology, Temasek 36 Life Science Laboratory, 1 Research Link, National University of Singapore, 37 Singapore, 117604. 38 39 Phone: 65-68727473. Fax: 65-68727007. E-mail: kwang@tll.org. sg. 40 41 42 43 Copyright © 2010, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved. J. Virol. doi:10.1128/JVI.02175-09 JVI Accepts, published online ahead of print on 13 January 2010
Neurocognitive Adaptations Designed for Social Exchange.

Instead of keeping things, [! Kung] use them as gifts to express generosity and friendly intent, and to put people under obligation to make return tokens of friendship. In reciprocating, one does not give the same object back again but something of comparable value. Eland fat is a very highly valued gift . Toma said that when he had eland fat to give, he took shrewd note of certain objects he might like to have and gave their owners especially generous gifts of fat.
Assessment of the Centex Chapter of the American Society for Public Administration

Abstract . i Chapter One: Introduction and Statement o f the Research Purpose Introduction . 1 Research Questions . 1 Chapter Summaries . 2 Chapter Two: Literature Review: Public administration Introduction . 4 Defining Public Administration . 5 Indeterminate Nature of Public Administration . 6 Art or Science . 7 Definitions of Public Administration . 9 . Social Functions of Public Administration 10 Professionalism in Public Administration . 12 Chapter Three: Literature Review: Professional Associations Introduction . 16 The Professional Association . 16 Functions of Local Professional Associations . 22 Networkingopportunities . 23 Access to Information . 23 Skill Development . 24 . Conducting a Needs Assessment 24 Conceptual Framework . 27 Chapter Four: Sett ing: ASPA and the Centex Chapter Purpose . 31 American Society for Public Administration . 31 Structure . 32 Centex Chapter . 34 . Purpose 34 Structure . 34 . Programs and Services 35 . Recent History 35 Chapter Five: Methodology Purpose . 37 Research Design . 37 Sample . 39 . Operationalization of the Conceptual Framework 39 Chapter Six: Results Introduction . 43 Membership Profile . 43 Networking Opportunities . 45 Access to Information . 47 SkillDevelopment . 48 Summary . 50 Cross-tabulation . 50 Chapter Seven: Recommendations and Conclusion Introduction . 53 . Survey Recommendations 53 . Cross.tabulation 54 . Member Recommendations 55 . Notification 55 Location of Events . 56 Conferences . 56 . New Services 57 Conclusion . 57 Appendices Appendix A: The Survey Instrument . 60 Appendix B: Centex Chapter Constitution . 66 Appendix C: Colleges and Universities . 71 Members Received Degrees From . 72 Members are Currently Enrolled . 73 Appendix D: Cross-tabulation Tables . 74 . Current Programs 75 Futureprograms . 81 Bibliography . Bibliography 83