Miracle-dz/UniFAR-FTUs huggingface dataset:
REVOLUTIONIZING PRE-CALCULUS EDUCATION: PHOTOMATH'S AI-POWERED MATHEMATICS TUTORSHIP

Mathematics plays a vital role in education; however, Filipino students encounter difficulties, evident in their performance on both national and international assessments. However, current literature suggests that leveraging technology, such as calculators and AI, in mathematics education can enhance students' proficiency, particularly in the pre-calculus domain. Thus, this research study examined the effectiveness of Photomath in enhancing Filipino students' self-reliance, interest, and performance in pre-calculus. A quasi-experimental one-group pretest-posttest design was used, with 49 Grade 11 students from NEUST Laboratory High School participating. Descriptive and inferential statistical analyses were performed to examine the pre-and post-intervention data. Results revealed a significant increase in students' self-reliance, interest, and performance in pre-calculus following the use of Photomath. The mean scores on all three measures increased significantly from the pretest to the posttest. The results of the t-tests further confirmed the effectiveness of Photomath in enhancing students' self-reliance, interest, and performance in pre-calculus. These results suggest that Photomath can be a valuable tool for educators to incorporate into pre-calculus teaching to enhance students' confidence and interest, foster intrinsic motivation, and ultimately improve their performance. Keywords: Photomath, students’ interest, students’ self-reliance, performance in pre-calculus
Prevalence and Determinants of Internet Addiction (IA) and its Association with Psychological Distress and Quality of Life Among Adolescents and Young Adults from a Rural Block of North India

To make communication easier, quicker, and to facilitate safe exchange of information internet was discovered. The use of internet in a healthy manner is defined as achieving a desired goal within an appropriate time period without experiencing intellectual or behavioural discomfort [1]. Over the years, ever increasing use of internet for work and leisure activities has led to its omnipresent presence across all activities of the day and this has disguised the boundaries between functional and dysfunctional internet use. This manifold uses of internet such as establishing risk-free social connections with strangers, free expression of thoughts, possibility to access prohibited content, involvement in unique games, and use of numerous other functions in privacy has led to exponential rise in the use of internet [2-4]. Some individuals cannot control their use of internet, whereas others can limit their use. Internet addiction (IA) can be described as an individual’s inability to control his or her own use of internet causing disturbances and impairment in fulfilment of work, social, and personal commitments [5-7]. Research literature suggests that depression is a leading comorbid disorder with IA [8]. The occurrence of depression among the young individuals with IA and existence of IA among the depressed individuals has been observed. The presence of low self-esteem, low motivation, fear of negative evaluation, social avoidance observed in depressed individuals are hypothesized to lead to excessive/addictive usage of internet in depressed individuals. Social isolation caused by IA may also lead to depressive symptoms. The research evidence suggests that depression can lead to addictive use of internet and vice-versa. Thus, both the mental health conditions have potential to influence and exacerbate each other. With this background, the current study is planned to investigate the prevalence, pattern and severity of IA, and its interrelationship with psychological distress and quality of life among the college going students. Research Questions
Attenuation Correction of X-band Polarimetric Doppler Weather Radar Signals: Application to Systems with High Spatio-Temporal Resolution

Attenuation Correction of X-band Polarimetric Doppler Weather Radar Signals: Application to Systems with High Spatio-Temporal Resolution In the last decade the atmospheric science community has seen widespread and successful application of X-band dual-polarization weather radars for measuring precipitation in the lowest 2 km of the troposphere. These X-band radars have the advantage of a smaller footprint, lower cost, and improved detection of hydrometeors due to increased range resolution. In recent years, the hydrology community began incorporating these radars in novel applications to study the spatio-temporal variability of rainfall from precipitation measurements near the ground, over watersheds of interest. The University of Iowa mobile XPOL radar system is one of the first to be used as an X-band polarimetric radar network dedicated to hydrology studies. During the spring of 2013, the Iowa XPOL radars participated in NASA Global Precipitation Measurements (GPM) first field campaign focused solely on hydrology studies, called the Iowa Flood Studies (IFloodS). Weather radars operating in the 3.2 cm (X-band) regime can suffer from severe attenuation, particularly in heavy convective storms. This has led to the development of sophisticated algorithms for X-band radars to correct the meteorological observables for attenuation. This is especially important for higher range resolution hydrology-specific X-band weather radars, where the attenuation correction aspect remains relatively unexamined. This research studies the problem of correcting for precipitation-induced attenuation in X-band polarimetric weather radars with high spatio-temporal resolution for hydrological applications. We also examine the variability in scattering simulations obtained from the drop spectra measured by two dimensional video disdrometers (2DVD) located in different climatic and
Survival after out of hospital cardiac arrest with prolonged period of resuscitation (250 minutes)

This paper outlines the case of prolonged resuscitation following an out of hospital cardiac arrest (OHCA). It discusses the pre-hospital and hospital management, including outcome from percutaneous coronary intervention (PCI) and intensive care stay. The patient had a 10-day ICU stay, where he demonstrated rapid improvement before being stepped down to a hospital ward where he ultimately self discharged. The discussion looks at factors involved in favourable outcome as well as the role of PCI in cardiac arrest in patient with no obvious non-cardiac cause.
A prática docente em uma escola ribeirinha na ilha do Marajó: um estudo preliminar em contexto naturalístico* The teacher's practice in a riverside school at the Marajó island: a preliminary study in the natural context

The objective of this research was to describe the teacher's practice in a riverside school context. Participated of this study, a teacher and her students from an amazon school located in the Marajo island in the state of Para. To collect the data, it was utilized two techniques of the methodology of the qualitative research: the participant observation of the classes (diary notes) and the interviews. The initial conclusions revealed that the teacher's practice is accomplished in a dissatisfactory way because of the short interaction of the various dynamic systems that constitute the context beside the bad conditions of the school, without educational resources and teacher's education.
Identification of a New Integration Site and Study on Site-Specific Integration in CHO-K1 Cells

Site-specific integration is an important approach used to address the problem of unstable cell lines in industry. In this study, we observed a reduction in the gene copy number and antibody production in a CHOK1 cell line BA03 capable of high antibody expression. We identified a new integration site named locus 7 in the intron region of the parva gene through sequencing, FISH, and genome walking. We demonstrate that the integration of the exogenous gene at this locus does not affect the transcription of the parva and, therefore, has a minimal impact on cell growth. We designed sgRNA and donor vectors to integrate the etanercept-coding gene into locus 7 and obtained a cell line, SSI-4. We performed a passaged stability study on SSI-4 and proved the possibility of the stable, site-specific integration of exogenous genes at this locus in terms of integration site, copy number, expression level, and cell growth. In summary, our study has identified a new integration site suitable for site-specific integration, which lays the foundation for the subsequent development of site-specific integration cell lines.
Empowering sustainability: Maximizing Carbon Emission Reduction through Renewable Energy Microgrid, Demand Response, and Battery Storage Optimization

--This study highlights the need for innovative, climate-smart solutions to power the future. It advocates a comprehensive approach involving renewable energy microgrids, demand response programs, and battery storage optimization to maximize carbon footprint reduction and sustainability. Collaboration between policymakers, utilities, and consumers is essential for widespread adoption. The study identifies several key outcomes: Optimal energy production, optimal energy storage, optimal demand response, and net energy balance. During optimization, carbon emissions were reduced to 72.75 kg CO2, exceeding the original target of 83.39 kg CO2. Additionally, comparing carbon emissions under different scenarios highlights the environmental benefits of renewable energy. Compared to alternative energy sources, the integrated approach shows significant potential in reducing carbon emissions.
Annually recurring erythema annulare centrifugum – a rare entity

Erythema anulare centrifugum (EAC) is a rare cutaneous disease which is characterised by either superficial erythematous annular centrifugally migrating lesions with classic “trailing scale” or with deep gyrate erythema which has more infiltrated borders. This clinical entity was first described by Darier in 1916. Annually recurring erythema anulare centrifugum is a very rarely reported peculiar variant of EAC which has identical clinical and histopathological features to classic EAC1. Up to now very few similar cases are reported in the literature. Here we report a similar case of annually recurring erythema annulare centrifugum in a young Asian female.
Inhaled CD24-Enriched Exosomes (EXO-CD24) as a Novel Immune Modulator in Respiratory Disease

Acute Respiratory Distress Syndrome (ARDS) is a major health concern with urgent unmet need for treatment options. There are three million new ARDS cases annually, and the disease’s mortality rate is high (35–46%). Cluster of differentiation 24 (CD24), a long-known protein with multifaceted functions, is a small, heavily glycosylated, membrane-anchored protein which functions as an immune checkpoint control. CD24 allows for immune discrimination between Damage-Associated Molecular Patterns and Pathogen-Associated Molecular Patterns derived from pathogens. Exosomes are intraluminal vesicles which play an important role in intercellular communication. Exosomes offer the advantage of targeted delivery, which improves safety and efficacy. The safety and efficacy of EXO-CD24 is promising, as was shown in >180 ARDS patients in phase 1b/2a, phase 2b, and compassionate use. CD24 binds Damage-associated molecular patterns (DAMPs) and inhibits the activation of the NF-ĸB pathway, a pivotal mediator of inflammatory responses. In contrast to anti-inflammatory therapies that are cytokine-specific or steroids that shut down the entire immune system, EXO-CD24 acts upstream, reverting the immune system back to normal activity. Herein, the safety and efficacy of mEXO-CD24 is shown in murine models of several pulmonary diseases (sepsis, allergic asthma, Chronic Obstructive Pulmonary Disease(COPD), fibrosis). EXO CD24 can suppress the hyperinflammatory response in the lungs in several pulmonary diseases with a significant unmet need for treatment options.
Percepción y conocimiento sobre sepsis en pobladores de Lima, Perú durante la pandemia de la Covid-19

Objetivo: Determinar la percepción y nivel de conocimiento sobre sepsis durante la pandemia de la Covid-19 en pobladores de Lima, Perú. Material y métodos: Estudio descriptivo transversal utilizando encuestas electrónicas. Se incluyó a personas mayores de 18 años, residentes en Lima entre diciembre de 2020 y abril de 2021. Se excluyeron a personas relacionadas al área de salud. Resultados: Se realizaron 289 encuestas, la edad media de los encuestados fue 38±15 años y 63% fueron mujeres. El 64% respondió que había escuchado alguna vez la palabra sepsis; 63% tuvo la percepción de que sepsis es una infección potencialmente mortal, 18% no sabía, 8% inflamación severa y 7% como una reacción alérgica severa. El 53% no sabía que la Covid-19 puede desencadenar sepsis, mientras que 68% sabía que la sepsis puede desencadenar la muerte. Conclusión: La percepción más frecuente de sepsis en pobladores de Lima fue infección potencialmente mortal, sin embargo, más de la mitad no supo que la Covid-19 puede desencadenar sepsis.
An Experimental Evaluation Based on Direction Finding Specification for Indoor Localization and Proximity Detection

Radio-frequency technologies have been largely explored to deliver reliable indoor localization systems. However, at the current stage, none of the proposed technologies represent a de-facto standard. Although RSS-based (received signal strength) techniques have been extensively studied, they suffer of a number of side-effects mainly caused by the complexity of radio propagation in indoor environments. A possible solution is designing systems exploiting multiple techniques, so that to compensate weaknesses of a specific source of information. Under this respect, Bluetooth represents an interesting technology, combining multiple techniques for indoor localization. In particular, the BT5.1 direction finding specification includes the possibility of estimating the angle between an emitting device and an antenna array. The Angle of Arrival (AoA) provides interesting features for the localization purpose, as it allows estimating the direction from which a signal is propagated. In this work, we detail our experimental setting based on a BT5.1-compliant kit to quantitatively measure the performance in three scenarios: static positioning, mobility, and proximity detection. Scenarios provide a robust benchmark allowing us to identify and discuss features of AoA values also in comparison with respect to traditional RSS-based approaches.
Advancements in Glioma Care: Focus on Emerging Neurosurgical Techniques

Background: Despite significant advances in understanding the molecular pathways of glioma, translating this knowledge into effective long-term solutions remains a challenge. Indeed, gliomas pose a significant challenge to neurosurgical oncology because of their diverse histopathological features, genetic heterogeneity, and clinical manifestations. Relevant sections: This study focuses on glioma complexity by reviewing recent advances in their management, also considering new classification systems and emerging neurosurgical techniques. To bridge the gap between new neurosurgical approaches and standards of care, the importance of molecular diagnosis and the use of techniques such as laser interstitial thermal therapy (LITT) and focused ultrasound (FUS) are emphasized, exploring how the integration of molecular knowledge with emerging neurosurgical approaches can personalize and improve the treatment of gliomas. Conclusions: The choice between LITT and FUS should be tailored to each case, considering factors such as tumor characteristics and patient health. LITT is favored for larger, complex tumors, while FUS is standard for smaller, deep-seated ones. Both techniques are equally effective for small and superficial tumors. Our study provides clear guidance for treating pediatric low-grade gliomas and highlights the crucial roles of LITT and FUS in managing high-grade gliomas in adults. This research sets the stage for improved patient care and future developments in the field of neurosurgery.
Global systematic review of occupational health and safety outcomes among sanitation and hygiene workers

Introduction Sanitary workers are exposed to a variety of occupational hazards in a variety of working environments, which can result in occupational-related outcomes. As a result, the goal of this review was to identify occupational health and safety outcomes among sanitary workers worldwide. Methods PRISMA was used as flow diagram and PICOS was used review questions. The studies published in English were searched from databases and others methods ranging from 2000 to 2022. Boolean logic (AND, OR), MeSH, and keywords used: (Occupation *OR Job *OR Work) AND (Occupational related respiratory Symptoms *OR Disease) AND [Solid waste collectors (SWCs) *OR Street sweepers (SS) *OR Sewage workers and waste treatment (STWs)] AND (Countries). Results A total of 228 studies were identified from 23 countries across the world. Studies were found via PubMed (n = 40), Medline (n = 25), Embase (n = 11) and Global Health (n = 66) and Google scholar (n = 63) and from previous (n = 23). From 8,962 of eligible sanitary workers, about 4,742 (54%), 1714 (19%) and 1,441 (16%) were sewage, sweepers and solid waste workers, respectively. A total study (n = 51) were eligible for occupational health and safety outcomes. Of these, respiratory problems accounted 27 (52%) and Gastroenteritis 14 (27%). Conclusion Despite a large number of studies to date provides sanitary employees all over the world face occupational-related risks, hence more research is needed to enhance and quantify illness burden among sanitary workers.
Nusinersen demonstrates effectiveness in treating spinal muscular atrophy: findings from a three-year nationwide study in Korea

Introduction Nusinersen is the first drug approved for spinal muscular atrophy (SMA) treatment. In this study, we aimed to evaluate the long-term safety and efficacy of nusinersen, assess the therapeutic effects based on the treatment initiation timing and baseline motor function, and explore the perception of functional improvement from either parents or patients, utilizing 3-year nationwide follow-up data in South Korea. Methods We enrolled patients with SMA who were treated with nusinersen under the National Health Insurance coverage, with complete motor score records available and a minimum treatment duration of 6 months. To evaluate the motor function of patients, the Hammersmith Infant Neurological Examination-2 (HINE-2) was used for type 1 and the Expanded Hammersmith Functional Motor Scale (HFMSE) was used for types 2 and 3 patients. A significant improvement was defined as a HINE-2 score gain ≥5 for patients with type 1 and an HFMSE score ≥ 3 for patients with types 2 and 3 SMA. Effects of treatment timing were assessed. Patients with type 2 were further categorized based on baseline motor scores for outcome analysis. We also analyzed a second dataset from five tertiary hospitals with the information on parents/patients-reported impressions of improvement. Results The study comprised 137 patients, with 21, 103, and 13 patients representing type 1, 2, and 3 SMA, respectively. At the 3-year follow-up, the analysis encompassed 7 patients with type 1, 12 patients with type 2, and none with type 3. Nearly half of all enrolled patients across SMA types (42.8, 59.2 and 46.2%, respectively) reached the 2-year follow-up for analysis. Patients with type 1 SMA exhibited gradual motor function improvement over 1-, 2-, and 3-year follow-ups (16, 9, and 7 patients, respectively). Patients with type 2 SMA demonstrated improvement over 1-, 2-, and 3-year follow-ups (96, 61 and 12 patients, respectively). Early treatment from symptom onset resulted in better outcomes for patients with type 1 and 2 SMA. In the second dataset, 90.7% of 108 patients reported subjective improvement at the 1-year follow-up. Conclusion Nusinersen treatment for types 1–3 SMA is safe and effective in long-term follow-up. Early treatment initiation was a significant factor affecting long-term motor outcome.
Low-Cost Quasi-Planar Dielectric Patch Resonator Filters Shielded by AMC Surface

The traditional dielectric resonator filter (DRF) is costly due to the high profile, machining and positioning of individual dielectric blocks and supports, and the necessity of metallic enclosure. To tackle this problem, this article presents a novel dielectric patch resonator (DPR) filter shielded by the artificial magnetic conductor (AMC). The proposed resonator is realized by sandwiching a thin DPR between a bottom-grounded substrate and an AMC plate, where the AMC is realized by a mushroom-type electromagnetic bandgap (EBG) surface printed on a substrate. It is quasi-planar and therefore suitable for integration in multilayer circuits. Three resonator schemes utilizing different fundamental modes (TM01, TM11, and TE11) are presented. The resonant frequency, spurious free window, and quality factor of each scheme are investigated by parametric analysis. The merit of high-quality factor (around 900 to near 2500 at 19 GHz) can be found from the simulated results. Compared to the traditional dielectric resonator (DR), the proposed one features a lower cost as it allows multicoupled DPR to be manufactured as a monoblock and various coupling configurations (positive, negative, or mixed) to be printed on the shielding substrate. For demonstration, four bandpass filters (BPFs) are designed, fabricated, and measured. Good agreement can be observed between the simulated and measured results.
A XANES and Raman investigation of sulfur speciation and structural order in Murchison and Allende meteorites

Insoluble organic matter (IOM) and hydrothermally treated IOM extracted from two carbonaceous chondrites, Murchison and Allende, was studied using sulfur K‐edge XANES (X‐ray absorption near edge structure) and μ‐Raman spectroscopy, with the aim to understand their IOM's sulfur speciation and structural order, and how aqueous alteration or thermal metamorphism may have transformed these materials. We found that the sulfur‐functional group chemistry of both the Murchison IOM and hydrothermally treated IOM samples have a large chemical variability ranging from oxidation states of S−2 to S+6, and exhibit a transformation in their oxidation state after the hydrothermal treatment (HT) to produce thiophenes and thiol compounds. Sulfoxide and sulfite peaks are also present in Murchison. Sulfates considered intrinsic to Murchison are most likely preaccretionary in nature, and not a result of reactions with water at high temperatures on the asteroid parent body. We argue that the reduced sulfides may have formed in the CM parent body, while the thiophenes and thiol compounds are a result of the HT. Micro‐Raman spectra show the presence of aliphatic and aromatic moieties in Murchison's material as observed previously, which exhibits no change after HT. Because the Murchison IOM was modified, as seen by XANES analysis, absence of a change observed using micro‐Raman indicated that although the alkyl carbons of IOM were cleaved, the aromatic network was not largely modified after HT. By contrast, Allende IOM contains primarily disulfide and elemental sulfur, no organic sulfur, and shows no transformation after HT. This nontransformation of Allende IOM after HT would indicate that parent body alteration of sulfide to sulfate is not feasible up to temperatures of 300°C. The reduced sulfur products indicate extreme secondary chemical processing from the precursor compounds in its parent body at temperatures as high as 624°C, as estimated from μ‐Raman D band parameters. The Raman parameters in Allende IOM that was interpreted in terms of amorphous carbon with regions of large clusters of benzene rings, was transformed after the HT to those with fewer benzene rings.