Miracle-dz/UniFAR-FTUs huggingface dataset:
The impact of commercially available air purifiers on bronchial asthma and allergy symptoms

Air pollution and climate change have a significant impact on human health and well-being, and contribute to the onset and worsening of bronchial asthma, allergy and other chronic respiratory diseases. Reducing exposure to indoor environmental factors that have been shown to worsen asthma symptoms or exacerbate asthma is an important part of respiratory disease management strategies. Current evidence suggests that portable air purifiers could be a useful way of reducing exposure to pollutants, especially in children but also in adults. Air purifiers can reduce the concentration of triggers of asthma in indoor air, but the results supporting their benefits for breathing problems have not always been reproducible. This paper summarizes the effects of indoor air pollution on asthma and allergies in children and adults, and the effectiveness of air purifiers in reducing the effects of pollution.
IMPACT OF UV-A IRRADIATION ON THE INTESTINE OF FRESHWATER CRAYFISH PROCAMBARUS CLARKII.

Procambarus clarkii is a freshwater crustacean which spread all over the River Nile. It has become an important crustacean model organism in research on animal behaviour, environmental stress, toxicity and its economic role. Ultraviolet radiation (UVR) has negative effects on aquatic organisms. The present study was designed to evaluate the effects of UV-A irradiation on the intestine of the crayfish Procambarus clarkii. To carry out the investigation, specimens were firstly adapted in the Lab, then classified into three groups. The first group was chosen as the control (untreated group) and the other two groups were the treated ones. The first treated group was irradiated for 15 minutes of UV-A for two weeks while the second treated group was irradiated for 30 minutes of UVA for two weeks. Each treated group was lifted for two weeks for recovery after irradiation. After treatments, the intestine including circular and longitudinal muscles were examined. The structural integrity of the epithelium and myoepithelium of the intestine of the control and treated groups were assessed using histological, histochemical and electron microscopic techniques. The significance changes of histological and histochemical were observed in treated animal and discussed. The study revealed that after 15 min. of UV-A irradiation for two weeks, P. clarkii showed signs of damage of intestine and the damage increased with increasing the time of irradiation for 30 min. The damage included intestinal epithelial cells with cell membrane, irregular structure of cuticular layer and absence of organoids seen by electron microscopy. These necrotic effects of UV-A in intestinal cells in irradiated animals may cause lethal lesions. Incomplete recovery was observed in each group.
The Biopsychosocial and Spiritual Perspective on the Readiness to Quit Smoking: A Comprehensive Review

Smoking cessation is a major public health goal today as smoking has threatened the safety, health, and lives of millions of people in the global community. Therefore, the purpose of this study is to identify the role of biopsychosocial and spiritual factors towards the readiness to quit smoking and smoking cessation. The results of the study found that smoking behaviour adversely affects not only the biological aspects but also the psychological, social, and spiritual aspects. Apart from that, this study also found that the biological, psychological, social, and spiritual aspects also play an important role in determining the motivation of smokers to quit smoking holistically. Therefore, research and empirical evidence on the biopsychosocial and spiritual aspects are needed to help healthcare teams to identify the barriers and motivating factors to quit smoking.
A Commentary on Whitall and Colleagues’ 2020 Article “Motor Development Research: II. The First Two Decades of the 21st Century Shaping Our Future”

This commentary reflects on the discussions of Whitall et al.’s paper “Motor Development Research: II. The First Two Decades of the 21st Century Shaping Our Future. ” Comments focus on (a) the emergence and importance of the Developmental Systems approach to motor development, (b) the perceived ambiguity between Dynamic and Developmental Systems approaches, and (c) a case for the evolution of Developmental Motor Neuroscience from the field of Developmental Cognitive Neuroscience.
Effect of Auricular Acupressure on Acute Pain in Nursing Home Residents with Mild Dementia: A Single-Blind, Randomized, Sham-Controlled Study

Introduction Acute pain is a prevalent problem for dementia residents in nursing homes. A variety of intervention strategies have been applied to address this problem. However, there remains an issue of inadequate pain control. This study aims to explore the analgesic efficacy of auricular acupressure (AA) for dementia residents with acute pain in nursing homes. Methods A multicenter, single-blind, randomized, and sham-controlled clinical trial was performed in three nursing homes in Yinchuan, China. All of the 206 eligible patients with acute pain were randomly divided into two groups for real AA therapy or sham AA (at sham point stimulation) therapy. The primary outcome was measured with a face pain scale revised (FPS-R) score before the procedure, 5 min after the start of the intervention, and 5 min after finishing the procedure. Secondary outcomes covered three physiological parameters, adverse reactions observed, satisfaction level of caregivers, acceptance of patients, and additional use of analgesics. Results There was a significant difference in pain scores based on FPS-R between the two groups (p < 0.01). Pain score in the true AA group was 1.84 ± 0.23, compared with 2.22 ± 0.81 in the sham AA group. No adverse events were found during the whole procedure for all patients. The satisfaction level of caregivers and acceptance of patients in the real AA group were significantly higher than those in the sham AA group. Conclusion This study shows that real AA was an alternative analgesic modality in reducing acute pain in patients with mild dementia.
Optimasilisasi Pertumbuhan Bakteri E. Coli dan Bacillus Subtilis pada Media Edamame Agar

Tahapan proses pembuatan edamame agar yaitu pembuatan tepung edamame dan pembuatan edamame agar. Penelitian ini dilaksanakan bulan Juni 2021 bertempat di Laboratorium Analisis Pangan Politeknik Negeri Jember. Tujuan penelitian untuk mengetahui pertumbuhan E. coli dan Bacillus Subtillis pada edamame agar dan membuat SOP. Metode penelitian yang digunakan dengan membandingkan pertumbuhan bakteri Escherichia coli dan Bacillus Subtilis pada edamame agar dengan Nutrien agar lama inkubasi 12, 24 ,36 ,48 jam. Hasil penelitian menunjukkan bahwa Esherichia coli pada Edamame Agar dengan lama inkubasi 12, 24, 36, 48 jam yaitu 1,0 x 109, 1,8 x 109 , 2,0 x 1013, 4,0 x 1013 cfu/ml dan pada Nutrient Agar dengan lama inkubasi 12, 24, 36, 48 jam yaitu 1,8 x 109, 2,8 x 109, 3,8 x 1013, 5,0 x 1013 cfu/ml. Pada Edamame Agar Bacillus subtillis dengan lama inkubasi 12, 24, 36, 48 jam yaitu 3,5 x 1012, 4,3 x 1012, 1,3 x 1013, 6,5 x 1013 cfu/ml dan pada Nutrient Agar 12, 24, 36, 48 jam yaitu 5,0 x 1012, 6,5 x 1012, 1,8 x 1013, 7,3 x 1013 cfu/ml. Kesimpulan penelitian ini adalah E. coli dan Bacillus subtillis bisa tumbah pada media edamame agar dan Bacillus subtillis cepat beradaptasi dari pada E. coli dengan TPC Bacillus subtillis 6,5 x 1013 cfu/ml dan E. Coli 4,0 x 1013 cfu/ml, namun pertumbuhan bakteri pada media edamame agar tidak lebih baik dari media NA
Loop Closure Detection Based on Image Semantic Segmentation in Indoor Environment

When mobile robots run in indoor environment, a large number of similar images are easy to appear in the images collected, probably causing false-positive judgment in loop closure detection based on simultaneous localization and mapping (SLAM). To solve this problem, a loop closure detection algorithm for visual SLAM based on image semantic segmentation is proposed in this paper. Specifically, the current frame is semantically segmented by optimized DeepLabv3+ model to obtain semantic labels in the image. The 3D semantic node coordinates corresponding to each semantic label are then extracted by combining mask centroid and image depth information. According to the distribution of semantic nodes, the DBSCAN density clustering algorithm is adopted to cluster densely distributed semantic nodes to avoid mismatching due to the close distance of semantic nodes in the subsequent matching process. Finally, the multidimensional similarity comparison of first rough and then fine is adopted to screen the candidate frames of loop closure from key frames and then confirm the real loop closure to complete accurate loop closure detection. Testing with public datasets and self-filmed datasets, experimental results show that being well adapted to illumination change, viewpoint deviation, and item movement or missing, the proposed algorithm can effectively improve the accuracy of loop closure detection in indoor environment.
Dl-3-n-butylphthalide alleviates cognitive impairment in amyloid precursor protein/presenilin 1 transgenic mice by regulating the striatal-enriched protein tyrosine phosphatase/ERK/cAMP-response element-binding protein signaling pathway

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive impairment and the deposition of amyloid plaques in the brain. In a transgenic mouse model of AD, cognitive impairment and synaptic dysfunction were revealed to be associated with soluble amyloid oligomers and to occur prior to plaque formation. The results of our previous studies revealed that striatal-enriched protein tyrosine phosphatase (STEP)61 negatively regulated the β-amyloid protein-mediated ERK/cAMP-response element-binding protein (CREB) signaling pathway. Dl-3-n-butylphthalide (NBP) is a synthetic compound approved by the Food and Drug Administration of China for the treatment of ischemic stroke in 2002. Studies have shown that the neuroprotective effects of NBP involve multiple mechanisms. The present study further explored the mechanism of NBP therapy in amyloid precursor protein (APP)/presenilin 1 (PS1) transgenic mice, and the involvement of the STEP/ERK/CREB signaling pathway. The results suggested that NBP treatment effectively ameliorated the spatial learning and memory impairment of the APP/PS1 transgenic mice, which was assessed using a Morris water maze. In addition, NBP reduced amyloid-induced activation of STEP61 levels, while increasing phosphorylated (p)-ERK1/2 and p-CREB levels in the cerebral cortex and hippocampus of APP/PS1 transgenic mice by western blotting and immunostaining. In conclusion, the present study provided evidence to suggest that the new drug NBP improved amyloid-induced learning and memory deficits, likely through the regulation of the STEP/ERK/CREB pathway. The results revealed that NBP, as a multi-target drug, may exert a neuroprotective effect. Therefore, NBP may serve as an effective treatment for AD.
Feature screening for survival trait with application to TCGA high-dimensional genomic data

Background In high-dimensional survival genomic data, identifying cancer-related genes is a challenging and important subject in the field of bioinformatics. In recent years, many feature screening approaches for survival outcomes with high-dimensional survival genomic data have been developed; however, few studies have systematically compared these methods. The primary purpose of this article is to conduct a series of simulation studies for systematic comparison; the second purpose of this article is to use these feature screening methods to further establish a more accurate prediction model for patient survival based on the survival genomic datasets of The Cancer Genome Atlas (TCGA). Results Simulation studies prove that network-adjusted feature screening measurement performs well and outperforms existing popular univariate independent feature screening methods. In the application of real data, we show that the proposed network-adjusted feature screening approach leads to more accurate survival prediction than alternative methods that do not account for gene-gene dependency information. We also use TCGA clinical survival genetic data to identify biomarkers associated with clinical survival outcomes in patients with various cancers including esophageal, pancreatic, head and neck squamous cell, lung, and breast invasive carcinomas. Conclusions These applications reveal advantages of the new proposed network-adjusted feature selection method over alternative methods that do not consider gene-gene dependency information. We also identify cancer-related genes that are almost detected in the literature. As a result, the network-based screening method is reliable and credible.
Artificial intelligence in energy industry: forecasting electricity consumption through cohort intelligence & adaptive neural fuzzy inference system

ABSTRACT Demand forecasting is critical for energy systems, as energy is difficult to store and should only be supplied as needed. Researchers attempted to improve forecasts of energy consumption. However, they assume independent factors increase at a constant growth rate, which is unrealistic. Existing methods are designed to determine annual consumption, whereas energy-planning organizations rely on short- or medium-term consumption values. Therefore, we propose a new forecasting framework that introduces new models and scenarios. We apply a cohort intelligence-based adaptive neuro-fuzzy inference system (CI-ANFIS) with a subtractive clustering and grid partition approach to forecast net electricity consumption. One challenge in accurately predicting electricity consumption for specific projection intervals is missing values for factors independent of those known for existing net consumption. Then, we utilize a regression equation scenario approach. We test our framework using a real-world energy consumption dataset and show that our proposed framework outperforms the existing methods.
Medical Treatment with Albendazole of A Patient with Hepatic Cystic Echinococcosis who Should have Undergone Elective Surgery in the Context of Pandemic of COVID-19

Cystic echinococcosis (CE) is worldwide endemic parasitic zoonosis caused by tapeworm Echinococcus granulosus. In human, liver is most common organ affected up to 85%. Informal Working Group on Echinococcosis (IWGE) of World Health Organization (WHO) published a standard classification of the cysts based on ultrasound (1) and a consensus in 2010 suggesting treating with albendazol as first choice of treatment in uncomplicated CE1 and CE3a up to 5 cm (2). In the context of pandemic of COVID-19, patients who requires elective percutaneous or surgical treatment for symptomatic non-complicated hepatic CE must be delayed or suspended because this disease is not life threatening unless it's complicated and by the shortness of bed and the risk of intra-hospital COVID-19 infection. The aim of this case report is to describe the follow up of a patient with hepatic cystic echinococcosis who should have undergone elective precutaneous or surgical treatment, treated with albendazole in the context of a pandemic COVID-19.
Semi-rigid Ureteroscopy in Children Using Pneumatic Lithotripsy: Safety and Efficacy

Introduction: The first-line treatment of ureteric stones is done using (URS) and (ESWL). Pneumatic, electro-hydraulic, ultrasonic, and laser devices have been used for URS treatment . Small caliber ureteroscopes with laser lithotripsy are the traditional management for pediatric ureteral stones and have provided a more safe management with lower complication rates. Aim of the work: The aim of our study was to demonstrate the safety and efficacy of pneumatic lithotripsy in the management of ureteral stones in pediatric cases. Patients and Methods: Our prospective clinical study at Nephrology and Urology Minia University Hospital, involved semi-rigid ureteroscopy using pneumatic lithotripsy in 20 child with ureteric stones. All children (2-16 years old) attended at our outpatient clinic diagnosed with ureteric stones (< 15 mm in size) and indicated for surgery underwent URS. Upper ureteric stones will excluded in our study. Results: In the current research, the outcome of 20 children underwent ureteroscopy with the use of a semirigid ureteroscope for middle and lower ureteric stones have been described. Our stone-free rate was 90%, all the complications were noted in our study at the start. We have not experienced any case of ureteral avulsion, there had been a single case of intraoperative ureteric perforation with extravasation. Regarding post-operative residual hydronephrosis , in our study 70 % of cases had no postoperative hydronephrosis on 1-month follow up US, while 100% of cases showed no hydronephrosis on 3-6 month follow up.
Copulas and Portfolios in the Electric Vehicle Sector

How can investors unlock the returns on the electric vehicle industry? Available investment choices range from individual stocks to exchange traded funds. We select six representative assets and characterize the time-varying joint distribution of their returns by copula-GARCH models. They facilitate portfolio optimization targeted at a chosen combination of risk and reward. With daily data from 2012 to 2020, we illustrate the models’ applicability by building a minimum expected shortfall portfolio and comparing its performance to that of an equally weighted benchmark. Our results should be of interest to investors and risk managers seeking or facing exposure to the electric vehicle sector.
The Effect of Different EEG Signal Processing Techniques Applied to Hand Movement BCIs

This paper reports the research on the influence of different methods for feature extraction and classification of Electroencephalogram (EEG) data and how they can affect the accuracy of a Brain-Computer Interface (BCI) on interpreting the EEG signal due to Motor Imagery (MI). For this purpose, a BCI was built and programmed to run multiple Feature Extraction methods in time-domain for different ranges of frequencies and two Machine Learning classifiers. It was compared the Linear Discriminant Analysis (LDA) and the Support Vector Machine (SVM) machine learning techniques. It was concluded that EEG frequency bands have a great influence in the performance of the BCI, mainly for Alpha and Beta bands. Furthermore, by utilizing the SVM method, it was possible to identify differences on the performances of the feature extraction methods evidencing higher accuracies for the Willison Amplitude (WAMP) and a combination of WAMP and the Root Mean Square (RMS) techniques. Contrastingly, the LDA demonstrated a higher mean accuracy and lower standard deviation between the subjects, however compared to the SVM, it was not possible to detect meaningful differences between the time domain techniques. Therefore, it was verified that LDA is more robust with greater accuracy, in addition to having lower computational cost compared to SVM for the feature extraction techniques used in this article.
Evaluation of Percutaneous Pinning of Fractures of the Surgical Neck of the Humerus in Children and Adolescents

Background: Open or closed reduction with Kirschner wires, screws, and flexible nails has been documented for the treatment of displaced proximal humeral fractures, however percutaneous K-wire fixation is the most widely utilized procedure. Objective: This study aimed to evaluate short-term clinical and radiographic results of percutaneous pinning of surgical neck-humerus fractures in children and adolescents using k-wire. Patients and Methods: Our study was done on 18 patients with fractures of the surgical neck of the humerus at Zagazig University Hospital treated by percutaneous pinning using k-wire. The humerus fractures were followed up clinically and radiologically for 6 months. Neer and Horwitz classification was used to classify fractures. Constant-Murley shoulder scoring system were used to evaluate results. Results: According to Constant-Murley scoring system the result obtained were excellent in 14 patient (77.78%) and good only in 4 cases (22.22%). Concerning the complications of the current study, 11 cases had no complication (61.11%), 3 cases had stiffness (16.67%) and 4 cases had superficial infection (22.22%). 4 cases of superficial infection were treated with antibiotics and daily dressing. K-wires were not required to be removed early. All of them achieved excellent results. 3 cases of stiffness were completed by physiotherapy, 2 of which yielded good results and 1 of which yielded excellent results. Conclusion: Fractures of the surgical neck in children and adolescents can be successfully treated with percutaneous kwires technique, which provides stability after reduction of fractures. Early and adequate physiotherapy program gives better results regarding the range of motion.
Comparação da Acurácia na Classificação de Diferentes Texturas Entre Modelos Neuromórficos de Izhikevich

For the last years, the study of the neuromorphic touch got the spotlight because of its multiple’s applications in robotics and rehabilitation such as texture classification. In this paper it is used a neuromorphic model for the classification of the data from 8 different textures to see which one of the neurons modeled by Izhikevich presents most accuracy as a second layer neuron. After the tests, it was showed that from the 8 different neuron models presented, the one with the best accuracy was the low-threshold spiking model with 81,25%.
Determinants and Impact of Childhood Asthma in Outpatient Clinics of Family Medicine Centers of New Minia City

Background: Asthma prevalence in children has increased 58% since 1980. Asthma is a chronic inflammatory disorder characterized with the intermittent and variable periods of airway obstruction. Asthma accounts for 30% of pediatric hospitalizations, for approximately one third of school absences and for numerous other psychosocial complications. Childhood bronchial asthma has multifactor causations. Geographical location, environmental, racial, as well as factors related to behaviors and life-styles are associated with the disease. Aim: Our aim of this study is to identify the determinants of childhood asthma and to increase the awareness for house contacts of patients for the hazards of asthmatic determinants on health of their children. Methods: It was a descriptive study carried out on patients attending outpatient clinics in three medical centers in New Minia City, Minia governorate, Egypt, in the period between January and April 2019. Results: A total of 135 patients with already diagnosed asthma were included in this study, the age of the children ranged from one to ten years old . In our study there was high percent of asthmatic children live in house hold smokers, there was high percent of asthmatic children with exposure to perfumes, detergents and foods. Introduction Asthma is a chronic inflammatory disorder characterized with the intermittent and variable periods of airway obstruction. The pathophysiology of asthma involves chronic inflammation, airway hyper-responsiveness, bronchoconstriction, swelling of the airways and mucus obstruction. The etiology of asthma includes an interaction among genetic factors (predisposition to allergy), environmental influences (exposure to infectious agents, allergens or irritants) and psychological influences (stressful life events) (Mc Quaid E L and Walders N