Miracle-dz/UniFAR-FTUs huggingface dataset:
CURRENT ADVANCEMENTS AND COMPLICATIONS IN INTRATHECAL DRUG DELIVERY SYSTEM

Intrathecal drug delivery systems (IDDS) have emerged as a valuable treatment option for patients with chronic pain who have failed to achieve adequate relief with conventional therapies. These systems provide targeted delivery of medications directly to the cerebrospinal fluid, resulting in improved pain control and reduced systemic side effects. However, the use of IDDS is not without potential complications and considerations that must be addressed to ensure optimal patient outcomes. This comprehensive review examines the various complications associated with IDDS and the considerations that healthcare providers and patients need to be aware of. Surgical complications, such as infection, bleeding, spinal fluid leaks, and nerve damage, are discussed, along with strategies to minimize these risks. Device malfunctions, including pump failure, catheter issues, and electronic problems, are explored, highlighting the importance of regular monitoring and maintenance. Medication-related side effects, such as nausea, sedation, and respiratory depression, are addressed, emphasizing the need for close monitoring and appropriate dosage adjustments. Long-term considerations, including tolerance to medication, physical dependence, and withdrawal symptoms, are also examined, emphasizing the significance of gradual tapering and proper discontinuation protocols. The review underscores the importance of regular follow-up appointments to assess the system's functionality, medication dosages, and patient response to treatment. By proactively managing and addressing complications, healthcare providers can optimize pain relief and minimize adverse effects, ensuring the long-term effectiveness and safety of IDDS.
Relation Between Oceanic Plate Structure, Patterns of Interplate Locking and Microseismicity in the 1922 Atacama Seismic Gap

We deployed a dense geodetic and seismological network in the Atacama seismic gap in Chile. We derive a microseismicity catalog of >30,000 events, time series from 70 GNSS stations, and utilize a transdimensional Bayesian inversion to estimate interplate locking. We identify two highly locked regions of different sizes whose geometries appear to control seismicity patterns. Interface seismicity concentrates beneath the coastline, just downdip of the highest locking. A region with lower locking (27.5°S–27.7°S) coincides with higher seismicity levels, a high number of repeating earthquakes and events extending toward the trench. This area is situated where the Copiapó Ridge is subducted and has shown previous indications of both seismic and aseismic slip, including an earthquake sequence in 2020. While these findings suggest that the structure of the downgoing oceanic plate prescribes patterns of interplate locking and seismicity, we note that the Taltal Ridge further north lacks a similar signature.
Robust Diagnosability of PEMFC Based on Bond Graph LFT

Fuel cell (FC) is one of the best alternatives of fossil energy. Recently, the research community of fuel cell has shown a considerable interest for diagnosis in view to ensure safety, security, and availability when faults occur in the process. The problematic for model based FC diagnosis consists in that the model is complex because of coupling of several kind of energies and the numerical values of parameters are not always known or are uncertain. The present paper deals with use of one tool: the Linear Fractional Transformation bond graph tool not only for uncertain modelling but also for monitorability (ability to detect and isolate faults) analysis and formal generation of robust fault indicators with respect to parameter uncertainties. Application concerns FC system.
Review of Vision-Based Deep Learning Parking Slot Detection on Surround View Images

Autonomous vehicles are gaining popularity, and the development of automatic parking systems is a fundamental requirement. Detecting the parking slots accurately is the first step towards achieving an automatic parking system. However, modern parking slots present various challenges for detection task due to their different shapes, colors, functionalities, and the influence of factors like lighting and obstacles. In this comprehensive review paper, we explore the realm of vision-based deep learning methods for parking slot detection. We categorize these methods into four main categories: object detection, image segmentation, regression, and graph neural network, and provide detailed explanations and insights into the unique features and strengths of each category. Additionally, we analyze the performance of these methods using three widely used datasets: the Tongji Parking-slot Dataset 2.0 (ps 2.0), Sejong National University (SNU) dataset, and panoramic surround view (PSV) dataset, which have played a crucial role in assessing advancements in parking slot detection. Finally, we summarize the findings of each method and outline future research directions in this field.
The Copper(II)-Thiodiacetate (tda) Chelate as Efficient Receptor of N9-(2-Hydroxyethyl)Adenine (9heade): Synthesis, Molecular and Crystal Structures, Physical Properties and DFT Calculations of [Cu(tda)(9heade)(H2O)]·2H2O

Considering that Cu(tda) chelate (tda: dithioacetate) is a receptor for adenine and related 6-aminopurines, this study reports on the synthesis, molecular and crystal structures, thermal stability, spectral properties and DFT calculations related to [Cu(tda)(9heade)(H2O)]·2H2O (1) [9heade: N9-(2-hydroxyethyl)adenine]. Concerning the molecular recognition of (metal chelate)-(adenine synthetic nucleoside), 1 represents an unprecedented metal binding pattern (MBP) for 9heade. However, unprecedentedly, the Cu(tda)-9heade molecular recognition in 1 is essentially featured in the Cu-N1(9heade) bond, without any N6-H⋯O(carboxyl tda) interligand interaction. Nevertheless, N1 being the most basic donor for N9-substituted adenines, this Cu-N1 bond is now assisted by an O2–water-mediated interaction (N6-H⋯O2 and O2⋯Cu weak contact). Also, in the crystal packing, the O-H(ol) of 9heade interacts with its own adenine moiety as a result of an O3–water-mediated interaction (O(ol)-H⋯O3 plus O3-H36⋯π(adenine moiety)). Both water-mediated interactions seem to be responsible for serious alterations in the physical properties of crystalline or grounded samples. Density functional theory calculations were used to evaluate the interactions energetically. Moreover, the quantum theory of atoms-in-molecules (QTAIM), in combination with the noncovalent interaction plot (NCIPlot), was used to analyze the interactions and rationalize the existence and relative importance of hydrogen bonding, chalcogen bonding and π-stacking interactions. The novelty of this work resides in the discovery of a novel binding mode for N9-(2-hydroxyethyl)adenine. Moreover, the investigation of the important role of water in the solid state of 1 is also relevant, along with the chalcogen bonding interactions demonstrated by the density functional theory (DFT) study.
Hilbert curves of quadric fibrations

Let [Formula: see text] be a quadric fibration over a smooth curve. The explicit equation of the corresponding Hilbert curve [Formula: see text] is obtained. The geometry of [Formula: see text] reflects some structure properties of [Formula: see text]; in particular, its special shape allows us to recognize that [Formula: see text] is a quadric fibration. In fact [Formula: see text] is reducible into [Formula: see text] parallel lines with prescribed slope, evenly spaced, plus a conic. On the other hand, this conic can itself be regarded as the Hilbert curve of a polarized surface only in very rare circumstances.
Distant Co-occurrence Patterns of Connectives: a Corpus Study of Formulaicity in Japanese

Using corpus research methods, this study aims to establish whether there are two-item and, more generally, multi-item distant co-occurrence patterns of connectives in written Japanese, and further, to clarify the role these patterns play in discourse. The study is based on a hybrid corpus of written Japanese including Humanities and social science papers, Science and technology papers, and general written language data. The co-occurrence threshold was set at co-occurrence frequency > 10, PMI value > 2, and Dice coefficient > 0.01. The distribution of the observed co-occurring pairs differed according to the genre. Visualization of the connectivity potential of co-occurring pairs as directed graphs showed that these co-occurring pairs constitute longer co-occurrence chains which can be interpreted as ready-made co-occurrence patterns. Two-item and multi-item co-occurrence patterns are considered a type of Bourdieu’s habitus and contribute to both discourse development and discourse prediction.
A time simulated annealing-back propagation algorithm and its application in disease prediction

In this paper, based on the Back Propagation (BP) neural network algorithm, we introduce the idea of the Simulated Annealing (SA), and then propose a new neural network algorithm: Time Simulated Annealing-Back Propagation (TSA-BP) algorithm. The proposed algorithm can improve the convergence rate and numerical stability. By using this proposed algorithm, the learning rates and initial weights in the BP neural network could be easily adjusted. We show that the TSA-BP algorithm could reduce the errors caused by human-made factors. Several numerical experiments have been tested by using different disease data. Furthermore, we compared the TSA-BP algorithm to the other existing, well-known algorithms. Numerical results show higher accuracy and efficiency of the TSA-BP algorithm.
The Effect of Septage Sludge and Oxidizing Agents in the Microbial Fuel Cells Generating Electricity

Earlier research demonstrated the efficacy of microbial fuel cells in both wastewater treatment and renewable electric current generation. In this process, microbial fuel cells harness the potential of wastewater as a substrate and energy source, enabling microorganisms to generate electric current. Introducing microorganisms sourced from septage sludge acts as a microbial catalyst. Additionally, tofu wastewater is employed as a nutritional resource to support the growth of these microorganisms. A dual-chamber reactor was utilized to carry out this study, featuring an anode and a cathode connected through a salt bridge. Various substrate variations were performed on the anode, specifically with a combination of tofu liquid waste and septage sludge at ratios of 1:1, 1:2, and 1:3. Additionally, different electrolyte solutions, such as KMnO4 and K3(Fe(CN)6), were used at the cathode. Using different electrolyte solutions as electron acceptors can enhance the electric current production generated. The study spanned 240 hours of operation, during which electric current, voltage, COD, and BOD measurements were taken at 48-hour intervals. The findings revealed that including septage sludge in a 1:3 ratio yielded the highest current strength compared to other substrate variations, measuring 16.34 mA. When using a 0.25 M KMnO4 as an electrolyte solution, the voltage recorded was 8.78 V. Additionally, the most effective removal of COD and BOD content was achieved with a substrate ratio of 1:3 in the presence of KMnO4, achieving removal rates of 95.12% and 96.45%, respectively. These results indicate that adding septage sludge contributes to increased electricity current production.
Oxidative Stress Response Kinetics after 60 Minutes at Different (1.4 ATA and 2.5 ATA) Hyperbaric Hyperoxia Exposures

Hyperbaric oxygen therapy (HBOT) is a therapeutical approach based on exposure to pure oxygen in an augmented atmospheric pressure. Although it has been used for years, the exact kinetics of the reactive oxygen species (ROS) between different pressures of hyperbaric oxygen exposure are still not clearly evidenced. In this study, the metabolic responses of hyperbaric hyperoxia exposures for 1 h at 1.4 and 2.5 ATA were investigated. Fourteen healthy non-smoking subjects (2 females and 12 males, age: 37.3 ± 12.7 years old (mean ± SD), height: 176.3 ± 9.9 cm, and weight: 75.8 ± 17.7 kg) volunteered for this study. Blood samples were taken before and at 30 min, 2 h, 24 h, and 48 h after a 1 h hyperbaric hyperoxic exposure. The level of oxidation was evaluated by the rate of ROS production, nitric oxide metabolites (NOx), and the levels of isoprostane. Antioxidant reactions were assessed through measuring superoxide dismutase (SOD), catalase (CAT), cysteinylglycine, and glutathione (GSH). The inflammatory response was measured using interleukine-6, neopterin, and creatinine. A short (60 min) period of mild (1.4 ATA) and high (2.5 ATA) hyperbaric hyperoxia leads to a similar significant increase in the production of ROS and antioxidant reactions. Immunomodulation and inflammatory responses, on the contrary, respond proportionally to the hyperbaric oxygen dose. Further research is warranted on the dose and the inter-dose recovery time to optimize the potential therapeutic benefits of this promising intervention.
Comparison of common carotid artery luminal diameter between adults with diabetes mellitus and healthy controls in North-eastern Nigeria

Background: Common carotid artery luminal diameter (CCALD) is used in epidemiological and interventional studies as biomarker of carotid atherosclerosis especially in subjects with DM. However, there are paucity of studies on the CCALD in subjects with DM in the study locality. Purpose: This study is aimed at evaluating the CCALD in adults with DM differ from those of healthy controls Methodology: Common carotid artery luminal diameters (CCALD) of 82 adult subjects with DM and 144 healthy controls were evaluated using a high-resolution ultrasound machine (Venue 50) equipped with electronic callipers and a linear array, high-frequency transducer (7-12 mHz). Measurements were taken at a point 1 cm distal to the carotid bulb. Results: The overall mean CCALD was 6.12±1.47 mm and 5.88±0.77 mm for subjects with DM and healthy controls, respectively. The mean CCALD value is higher in subjects with DM compared to those of healthy controls though; there was no statistically significant difference in CCALD between the two groups. There were significant positive correlations between CCALD and age in male subjects with DM (r=0.488) while weak negative correlation exists in females (r=-0.073). Furthermore, weak negative correlation between CCALD and age among healthy controls (r=-0.117 and -0.020 for males and females, respectively). Conclusion: The overall mean CCALD value in subjects with DM is higher than those of healthy control. The mean CCALD value is positively and significantly related to age in only male subjects with DM.
UIQI: A Comprehensive Quality Evaluation Index for Underwater Images

Due to the light absorption and scattering in waterbodies, acquired underwater images frequently suffer from color cast, blur, low contrast, noise, etc., which seriously degrade the image quality and affect their subsequent applications. Therefore, it is necessary to propose a reliable and practical underwater image quality assessment (IQA) model that can faithfully evaluate underwater image quality. To this end, in this article, we establish a novel quality assessment model for underwater images by in-depth analysis and characterization of multiple image properties. Specifically, we propose characterizing the image luminance, color cast, sharpness, contrast, fog density and noise to comprehensively describe the image quality to evaluate the underwater image quality more accurately. Dedicated features are elaborately investigated to characterize those quality-aware image properties. After feature extraction, we employ support vector regression (SVR) to integrate all the quality-aware features and regress them onto the underwater image quality score. Extensive tests performed on standard underwater image quality databases demonstrate the superior prediction performance of the proposed underwater IQA model to state-of-the-art congeneric quality assessment models.
Unconventional Monetary Policy or Automatic Stabilizers?:A Financial Post-Keynesian Comparison

The purpose of public policy, expansionary or contractionary, is to encourage the expansion of income, output, and employment. Theory decides the nature and kind of policy, and the underlying mechanics that result in expansion. Keynes (1964) brings money and a monetary production economy to the forefront of economic analysis, yet in the General Theory , he is skeptical of the efficacy of monetary policy. This paper analyzes how prices of assets, liabilities, and commodities interact in response to unconventional monetary policy and fiscal policy (namely automatic stabilizers) to create conditions that stimulate private investment and economic activity. Modern economics, after accepting the need for intervention, tends to attempt to use monetary policy to steer aggregate demand. “Unconventional” monetary policy such as zero and negative interest rates, and quantitative easing have been instituted in an attempt to fight slumps and stimulate economic activity without increasing government deficits. In this paper, we point out— using Davidson’s (1972) financial post-Keynesian framework—how unconventional monetary policy is not sufficient to create the conditions of backwardation that stimulate production. Finally, we explain how automatic stabilizers, using the Kalecki profits (price) equation, are the best avenue to create the conditions for backwardation that stimulate economic activity. We conclude, like Keynes, that fiscal policy is the reliable path to economic expansion.
Safety of Lumason® (SonoVue®) in special populations and critically ill patients

Evidence for the safe use of Lumason® (SonoVue®), an ultrasound enhancing agent (UEA), in special patient populations is critical to enable healthcare professionals to make informed decisions concerning its use in such patients. Herein, we provide insight on the safety and tolerability of Lumason® in special patient populations. Findings are presented from clinical pharmacology studies conducted in patients with compromised cardiopulmonary conditions, from a retrospective study performed in critically ill patients, and from post-marketing surveillance data from over 20 years of market use of Lumason® (SonoVue®). No detrimental effects of Lumason® on cardiac electrophysiology were observed in patients with coronary artery disease (CAD), and no significant effects on pulmonary hemodynamics were noted in patients with pulmonary hypertension or congestive heart failure. Similarly, no effects on several assessments of pulmonary function (e.g., FVC) were observed in patients with chronic obstructive pulmonary disease (COPD), and no clinically meaningful changes in O2 saturation or other safety parameters were observed after administration of Lumason® to patients with diffuse interstitial pulmonary fibrosis (DIPF). The retrospective study of critically ill patients revealed no significant difference for in-hospital mortality between patients administered Lumason® for echocardiography versus those who had undergone echocardiography without contrast agent. Post-marketing surveillance revealed very low reporting rates (RR) for non-serious and serious adverse events and that serious hypersensitivity reactions were rare. These findings confirm that Lumason® is a safe and well tolerated UEA for use in special populations and critically ill patients.
BLACK FEMINISM IDEAS AS PORTRAYED IN HOMAGE TO MY HIPS POEM BY LUCILLE CLIFTON

This research discusses a poem written by Lucille Clifton entitled homage to my hips. The researchers aim to describe the portrayal of black feminism ideas inside the poem to raise awareness regarding the issues of discrimination toward the black community especially women. This study aims to answer the question of how is the black feminism ideas portrayed in the poem entitled homage to my hips by Lucille Clifton. This research used descriptive qualitative method typically library research with textual analysis since the data of this research are in the form of words and phrases within the stanza. The data source is the poem entitled Homage to My Hips poem by Lucille Clifton, and data sources are the poet’s background of life, journals, and previous studies. This research used intersectionality and black feminism thought theory as the approaches. In order to answer the research question, the researchers used the parameters of black feminism ideas according to the black feminist thought and intersectionality theory to capture the ideas of black feminism in the poem. The results of this research show that the poem entitled homage to my hips by Lucille Clifton is portrayed the ideas of black feminism, which strongly ignores and rejects the continuous approaches of the oppression system both in practice and the ideas that justify it, based on the parameters that cover the existence of black feminism according to the black feminist thought and intersectionality approaches.
Student-centred learning and teaching: a systematic mapping review of empirical research

ABSTRACT Student-centred learning and teaching (SCLT) has become a widespread approach in higher education and is praised by students, educational researchers and policy makers alike. SCLT is believed to help students become self-directed learners by placing them at the centre of the learning process. Despite the central role currently ascribed to SCLT in higher education, systematic knowledge about how it is practiced in higher education is limited. Informed by the findings of a systematic mapping review of empirical research, this article discloses how SCLT is practised inclass, outof-class and institutionally in higher educational institutions. Overall, we find that empirical research on SCLT is diverse and covers a wide range of pedagogical approaches and methods. Even so, the main focus of the research mapped is on in-class learning activities, whereas less focus is placed on student support systems and on how to develop a SCLT culture in institutional practices. Furthermore, the review finds an extensive focus on student activation and engagement in the empirical research on SCLT. This runs contrary to the theoretical literature arguing that SCLT should promote student agency and autonomy. We therefore encourage more empirical research on the relationship between SCLT and student agency in higher education.
TRANSLATION SHIFT USED IN ECONOMIC BILINGUAL TEXT BOOK

The aims of this study were to find out the kinds of translation shift in translation of Economic Bilingual Text Book, to describe the pattern of shift used by Economic Bilingual Text Book to bridge the different grammatical structures between Indonesia and English, and to explain about the reason of translation shift used in Economic Bilingual Text Book. The research was conducted by using qualitative descriptive design. The data of this study was clauses that were translated from Bahasa Indonesia into English by Mulyadi, E. , and Mardiyatmo (2009) on an Economic Bilingual text book ‘Economics 1’ for Junior High School Year VII as the source of data. The data was analyzed by using the Theory of Translation Shift based on (Catford: 1965) to find the types and the ways of translation shift used in economic bilingual text book and the reasons of translation shift were used in Economic Bilingual Text Book based on Newmark (1988:85). The results of this study were (1) there were four types of category shifts namely structure shift, class shift, unit shift and intra- system shift. (2) there were some ways of translation shift used in Economic Bilingual Text Book, namely an adjective may be translated into a noun, a conjunction shifted into a adverb, an adverb may be translated into an adjective, and (3) there were four reasons behind the occurrence of shifts namely: when SL and TL have different language systems, when the grammatical structures of SL do not exist in TL, where literal translation is grammatically possible but may not accord with natural usage in the TL so it is the matter of naturalness between SL and TL and to replace virtual lexical gap by a grammatical structure.