Miracle-dz/UniFAR-FTUs huggingface dataset:
Serum high-density lipoprotein level and prognosis of ovarian cancer

This study aimed to investigate the prognostic value of serum high-density lipoprotein (HDL) level in patients with ovarian cancer. This study enrolled 152 patients diagnosed with ovarian cancer and 119 patients with benign ovarian tumors. The associations of patient characteristics and disease with survival were determined using Cox regression analysis, t tests, analysis of variance for multiple-group comparisons, and chi-square tests. The potential association between HDL levels and the clinical characteristics of the disease was also analyzed. The diagnostic value of HDL was estimated using receiver operating characteristic curve analysis and calculation of the area under the curve. Progression-free survival and overall survival were determined using the Kaplan–Meier method, and their associations with patient and pathological variables, including HDL, were determined using the log-rank test. The median serum HDL was 1.15 mm measured in 152 patients with ovarian cancer and 1.30 mm in 119 patients with benign ovarian tumors (P = .000054). The receiver operating characteristic curve analysis yielded an area under the curve of 0.735 for serum HDL levels. Serum HDL levels were significantly associated with tumor pathological types (non-serous vs serous, P < .05). No association was observed between serum HDL levels and patient age, age at menarche or marriage, number of children, tumor grade, or clinical stage (P > .05). Patients with high serum HDL levels had a longer progression-free survival and overall survival than those with low serum HDL levels. Serum HDL levels are an independent prognostic factor for ovarian cancer.
Understanding multi-level barriers to medication adherence among adults living with sickle cell disease

There is limited research that identifies and examines multi-level barriers to medication adherence among adults with Sickle Cell Disease (SCD); Identify multi-level barriers to medication adherence among adults with SCD; and Examine the relationship between multi-level barriers and medication adherence levels. A cross-sectional study included 130 adults (ages ≥ 18 years old) living with SCD who receive treatment/care from one of the 10 adult SCD clinics within the Networking California for sickle cell care initiative. Study measures included the medication adherence report scale (Professor Rob Horne), Beliefs about Medicine Questionnaire (Professor Rob Horne), and patient reported outcomes measurement information system. Participants reported barriers to medication adherence across 3 levels: Community-level barriers (e.g., COVID-19 pandemic); Institutional-level barriers (e.g., bad experiences with the health care system); and Individual-level barriers (e.g., beliefs and depression severity). Depression severity and patient concerns about SCD medication were inversely correlated with medication adherence (rs = −0.302, P < .001; rs = −0.341, P < .001 respectively). Patient beliefs about the necessity of SCD medication were insignificantly correlated with medication adherence (rs = 0.065, P = .464). Medication adherence was higher among patients who had fewer adherence barriers than multiple adherence barriers (Median medication adherence: fewer barriers = 22 vs multiple barrier = 20.50, P = .085), suggesting clinical significance although statistically insignificant. Identifying multi-level adherence barriers and examining their relationship with medication adherence will help develop targeted public health strategies to promote improved medication adherence and wellness among adults with SCD.
Nonviral Liver Disease Burden in People Living With HIV and Elevated Transaminases: A Cross-Sectional Study

Introduction: Because of improved life expectancy in people living with HIV (PLWH), liver disease is increasingly being recognized. We assessed nonviral chronic liver disease burden in PLWH. Methods: The HIV non-virAL liver disease study (2014–2021) prospectively recruited PLWH with elevated serum alanine aminotransferase levels and negative hepatitis serology. Clinically significant hepatic fibrosis (CSHF) was defined as liver stiffness measurement of >7.1 kPa and hazardous alcohol use as Alcohol Use Disorders Identification Test score ≥ 8. Primary outcome was prevalence/predictors of CSHF. Results: Total recruited were n = 274, 92% male, median age 52 (45–59) years, and 96% having undetectable HIV viral load. Overall, n = 97 (35%) had hazardous alcohol use, n = 72 (26%) had metabolic syndrome, and 17%–27% had exposure to hepatotoxic antiretrovirals. Prevalence of CSHF was 20% (n = 54), prevalence of cirrhosis (liver stiffness measurement > 12.5 kPa) being 7% (19/274). Risk factors for CSHF were hazardous alcohol use in 44% (n = 24), metabolic syndrome in 46% (n = 25), and hepatotoxic antiretrovirals in 56% (n = 30), most having more than one risk factor. Independent predictors of CSHF were serum high-density lipoprotein (odds ratio [OR] 0.220; 95% confidence interval [CI]: 0.061 to 0.790, P = 0.020) (inverse relationship); serum aspartate aminotransferase (OR 1.033, 95% CI: 1.001 to 1.067, P = 0.045), and didanosine use (OR 2.878, 95% CI: 1.228 to 6.774, P = 0.015). Moderate–severe hepatic steatosis was identified in 52% (n = 142). FIB-4 and aspartate aminotransferase-to-platelet ratio index performed poorly in predicting CSHF (positive predictive value 27.3% and 30.6%, respectively) and advanced fibrosis (≥F3) (positive predictive value 17.6% and 5.9%, respectively). Conclusion: In this study, 20% of PLWH had CSHF associated with high prevalence of hazardous alcohol use/metabolic syndrome/potentially hepatotoxic antiretrovirals. These potentially modifiable risk factors need addressing.
Validity and Reliability of the Acceleration-Speed Profile for Assessing Running Kinematics' Variables Derived From the Force-Velocity Profile in Professional Soccer Players

Abstract Alonso-Callejo, A, García-Unanue, J, Guitart-Trench, M, Majano, C, Gallardo, L, and Felipe, J. Validity and reliability of the acceleration-speed profile for assessing running kinematics' variables derived from the force-velocity profile in professional soccer players. J Strength Cond Res 38(3): 563–570, 2024—The aim of this research is to assess the validity and reliability of the acceleration-speed profile (ASP) for measuring the mechanical variables of running kinematics when compared with the force-velocity profile (FVP) obtained by reference systems. The ASP and FVP of 14 male players of an elite football club were assessed during a competitive microcycle. Three ASPs were tested according to the number and type of sessions included in its plotting (ASP1: 5 training sessions and competitive match; ASP2: 5 training sessions; ASP3: competitive match). Force-velocity profile was tested 4 days before match (MD-4) with a 30-m linear sprint using 3 previously validated devices (encoder, mobile App, and global positioning system). Level of significance was p < 0.05. Acceptable reliability (intraclass correlation coefficient > 0.5) was found between the ASP1 and the encoder for all variables (F0-A0, V0-S0, and Vmax). The more reliable ASP method was the ASP1 showing a lower bias than the ASP2 and ASP3 methods for almost all variables and reference systems. For ASP1, lower mean absolute error (MAE: 0.3–0.5) and higher correlation (P-M corr: 0.57–0.92) were found on variables related to the velocity in comparison with variables related to the early acceleration phase (F0-A0; MAE: 0.49–0.63; P-M corr: 0.13–0.41). Acceleration-speed profile, when computed with data from a complete competitive week, is a reliable method for analyzing variables derived from velocity and acceleration kinematics. From these results, practitioners could implement ASP and the applications of the FVP previously studied, such as resistance training prescription, performance assessment, and return-to-play management.
Analysis of trends in retinopathy of prematurity over 5 years in a tertiary neonatal intensive care unit

The aim of the study was to look at the incidence and trend of retinopathy of prematurity (ROP) between 2017 and 2021 in a tertiary neonatal intensive care unit (NICU) in Australia and to compare potential modifiable risk factors of ROP between preterm infants who required treatment for ROP and who did not need treatment.
Exploring traditional Chinese medicine as a potential treatment for sarcopenia: A network pharmacology and data mining analysis of drug selection and efficacy

Sarcopenia, as an increasingly pressing clinical issue, can be ameliorated through employment of traditional Chinese medicines. However, the current lack of specific pharmacological interventions for Sarcopenia necessitates further exploration of novel possibilities in traditional Chinese medicine for the treatment of this condition, utilizing advanced methodologies such as web pharmacology and data mining. Screening the essential targets of Sarcopenia, conducting matching between target and active molecules, as well as active molecules and herbs. Employing data mining techniques to analyze the screening outcomes, and molecular docking to compare the binding activities of active molecules with target proteins. The approach of using herbs for the treatment of Sarcopenia involves 13 targets, with 414 active compounds and 367 types of herbs. Data mining reveals that the herbs used in treating Sarcopenia are primarily characterized by their bitter taste, exerting their effects through dispelling dampness and promoting blood circulation. Moreover, 2 new formulas are postulated. Furthermore, molecular docking analysis indicates that the main active components of the herbs can be observed to tightly bind with the targets. Through network pharmacology and molecular docking, our findings reveal that herbs contain 15 key active components and 5 key targets, which correspond to 7 major herbs and 2 new formulas. Academically, these findings hold significant reference value for the development of novel drugs targeting Sarcopenia.
Aerobic Rice: Benefits without going to the Gym?

Rice, a staple food for over 70% of Asians, is also the single biggest user of water, requiring 2‐3 times more water per unit of grain produced than crops such as wheat and maize. With growing populations, increased urbanisation and environmental degradation, the supply of fresh water is depleting. Recognising the water constraints to rice yield, the aim of the project entitled ‘Developing a System of Temperate and Tropical Aerobic Rice (STAR) in Asia’ was to develop water‐efficient aerobic rice technologies. This paper highlights the success of that project.
A feasibility study of smartphone sensors to assess the effect of acute high altitude (3,800 m) exposure on cognition and motor function in healthy participants

Acute exposure to hypoxia at attitude has neurologic effects. Some subjects develop severe neurologic symptoms, including Parkinsonism, when hypoxic at high altitude as part of an Acute Mountain Sickness syndrome. Digital health technologies can provide continuous monitoring and objective, real-world measures of movement disorders, but only limited validation data of wearable sensors is available in the high-altitude setting. This equipment validation and feasibility study assessed smartphone microphone and accelerometer function at sea level and 12470 feet (3,800 m) to assess their potential value to predict and prevent neurologic features of acute mountain sickness. A feasibility study of standardized assessments of motor, speech and cognitive tasks was performed in 3 normal subjects at sea level and at altitude. All subjects were hypoxic at altitude with O2 saturations ranging from 77-81%. Shaker table (range of frequencies) and high-fidelity speaker (range of frequencies) controls confirmed high correlation of observed and expected measurements for microphone and accelerometer under all conditions. The feasibility study demonstrated that under conditions of hypoxia at attitude, fine motor skills are impaired; visual short-term memory is not impaired but has longer response time; gait and balance is impaired, and a postural tremor develops with frequencies below 10 Hz. Future studies could use these wearable sensors to further assess effects at altitude of more severe hypoxia with applications in the high-altitude environment for Parkinson’s Disease patients, with further opportunity for aviation and military use.
Reversal of the regional-scale flow system of the Williston basin in response to Pleistocene glaciation

Low δ18O values of formation waters, collapse structures related to salt dissolution, hydrodynamic blowout structures, and biodegradation of oils all suggest a significant influx of fresh water into the Williston basin along the outcrop belt in southern and central Manitoba during Pleistocene glaciation. The thickness of the continental ice sheet over Manitoba would have provided sufficient potentiometric drive to reverse the regional-scale flow system of the Williston basin. The dynamic nature of the flow system suggests that modern-day pressure distributions may not be good proxies for ancient petroleum migration pathways as is commonly assumed.
A Preliminary Study toward Consistent Soil Moisture from AMSR2

AbstractA preliminary study toward consistent soil moisture products from the Advanced Microwave Scanning Radiometer 2 (AMSR2) is presented. Its predecessor, the Advanced Microwave Scanning Radiometer for Earth Observing System (AMSR-E), has provided Earth scientists with a consistent and continuous global soil moisture dataset. A major challenge remains to achieve synergy between these soil moisture datasets, which is hampered by the lack of an overlapping observation period of the sensors. Here, observations of the multifrequency microwave radiometer on board the Tropical Rainfall Measuring Mission (TRMM) satellite were used to improve consistency between AMSR-E and AMSR2. Several scenarios to achieve synergy between the AMSR-E and AMSR2 soil moisture products were evaluated. The novel soil moisture retrievals from C-band observations, a frequency band that is lacking on board the TRMM satellite, are also presented. A global comparison of soil moisture retrievals against ERA-Interim soil moisture demons.
A comparison of viewer reactions to outdoor scenes and photographs of those scenes

A color-slide projection or photograph can be used to determine reactions to an actual scene if the presentation adequately includes most of the elements in the scene. Eight kinds of scenes were subjected to three different types of presentation: (A) viewing. the actual scenes, (B) viewing color slides of the scenes, and (C) viewing color photographs of the scenes. For each scene, responses to each of the three treatments were compared statistically and graphically.
Asymptotics and Improvements of Sieving for Codes

A recent work by Guo, Johansson, and Nguyen (Eprint’23) proposes a promising adaptation of Sieving techniques from lattices to codes, in particular, by claiming concrete cryptanalytic improvements on various schemes. The core of their algorithm reduces to a Near Neighbor Search (NNS) problem, for which they devise an ad-hoc approach. In this work, we aim for a better theoretical understanding of this approach. First, we provide an asymptotic analysis which is not present in the original paper. Second, we propose a more systematic use of well-established NNS machinery, known as Locality Sensitive Hashing and Filtering (LSH/F). LSH/F is an approach that has been applied very successfully in the case of sieving over lattices. We thus establish the first baseline for the sieving approach with a decoding complexity of 2 0 . 117 n for the conventional worst parameters (full distance decoding, where complexity is maximized over all code rates). Our cumulative improvements eventually enable us to lower the hardest parameter decoding complexity for SievingISD algorithms to 2 0 . 101 n . This approach outperforms the BJMM algorithm (Eurocrypt’12) but falls behind the most advanced conventional ISD approach by Both and May (PQCrypto’18). As for lattices, we found the Random-Spherical-Code-Product (RPC) to give the best asymptotic complexity. Moreover, we also consider an alternative that seems specific to the Hamming Sphere, which we believe could be of practical interest as it plausibly hides less sub-exponential overheads than RPC.
Water-Processable, Stretchable, and Ion-Conducting Coacervate Fibers from Keratin Associations with Polyelectrolytes

Nucleocytoplasmic transport (NCT) is affected in several neurodegenerative diseases including C9orf72‑ALS. It has recently been found that arginine‑containing dipeptide repeat proteins (R‑DPRs), translated from C9orf72 repeat expansions, directly bind to several importins. To gain insight into how this can affect nucleocytoplasmic transport, we use coarse‑grained molecular dynamics simulations to study the molecular interaction of poly‑PR, the most toxic DPR, with several Kapβs (importins and exportins). We show that poly‑PR–Kapβ binding depends on the net charge per residue (NCPR) of the Kapβ, salt concentration of the solvent, and poly‑PR length. Poly‑PR makes contact with the inner surface of most importins, which strongly interferes with Kapβ binding to cargo‑NLS, IBB, and RanGTP in a poly‑PR length‑dependent manner. Longer poly‑PRs at higher concentrations are also able to make contact with the outer surface of importins that contain several binding sites to FG‑Nups. We also show that poly‑PR binds to exportins, especially at lower salt concentrations, interacting with several RanGTP and FG‑Nup binding sites. Overall, our results suggest that poly‑PR might cause length‑dependent defects in cargo loading, cargo release, Kapβ transport and Ran gradient across the nuclear envelope. The
The Influence of Accounting Information Systems on Internal Control of Receivables (Study at one of the telecommunications companies in Bandung)

This study aims to investigate the impact of variables related to the accounts receivable accounting information system and accounts receivable internal control on a telecommunications company located in Bandung. Based on the obtained calculation results, it has been determined that the accounting information system for accounts receivable can be classified as moderately satisfactory. At the same time, the internal control measures for accounts receivable can also be classified as moderately satisfactory. The research findings indicate a significant correlation of 0.840 between variables X and Y, suggesting a strong relationship between the accounts receivable accounting information system and accounts receivable internal control. According to the analysis conducted using simple linear regression, it has been shown that the relationship between the dependent variable Y and the independent variable X, representing accounts receivable in the accounting information system, can be expressed as Y = 7.180 + 0.729X. This condition implies that for each unit rise in the accounts receivable; there is an associated increase of 0.729 units in the dependent variable. The coefficient analysis reveals that the accounts receivable accounting information system significantly contributes to the internal control of accounts receivable, accounting for 70.6% of the overall influence. The remaining 29.4% can be attributed to various other factors.
Water resources data Kansas, water year 2005

2006 III PREFACE This volume of the annual hydrologic data report for Kansas is one of a series of annual reports that document hydrologic data gathered from the U.S. Geological Survey's surface-and groundwater data-collection networks in each State, Puerto Rico, and the Trust Territories. These records of streamflow, groundwater levels, and water quality provide the hydrologic information needed by local, State, and Federal agencies, and the private sector for developing and managing our Nation's land and water resources. This report is the culmination of a concerted effort by dedicated personnel of the U.S. Geological Survey who collected, compiled, analyzed, verified, and organized the data, and who typed, edited, and assembled the report. The authors had primary responsibility for assuring that the information contained herein is accurate, complete, and adheres to Geological Survey policy and established guidelines. This report was prepared in cooperation with the State of Kansas and with other agencies under the general supervision of James E.
La precipitación en el Pirineo español: diversidad espacial en las tendencias y escenarios futuros

This paper analyses the spatial and temporal precipitation patterns in the Spanish Pyrenees since 1950. A multi-parametric approach is used by means of the analysis of total precipitation amount but also considering other important parameters such as the number of rainy days, the duration of the dry spells and the extreme precipitation events. Results show a general decrease of precipitation in second half of the twentieth century mainly in spring and summer. The precipitation decrease is mainly explained by the reduction in the frequency of the most intense precipitation events. Trend in rainy days has a great spatial and seasonal variability. The climate change models show in the Spanish Pyrenees a general decrease of precipitation amounts throughout the twentieth-one century, also showing a decrease in the frequency of days rainy, an increase of the intensity of the most extreme events and a noticeable increase in the duration of the dry spells.
Reassessing the variability in atmospheric H2 using the two‐way nested TM5 model

This work reassesses the global atmospheric budget of H2 with the TM5 model. The recent adjustment of the calibration scale for H2 translates into a change in the tropospheric burden. Furthermore, the ECMWF Reanalysis‐Interim (ERA‐Interim) data from the European Centre for Medium‐Range Weather Forecasts (ECMWF) used in this study show slower vertical transport than the operational data used before. Consequently, more H2 is removed by deposition. The deposition parametrization is updated because significant deposition fluxes for snow, water, and vegetation surfaces were calculated in our previous study. Timescales of 1–2 h are asserted for the transport of H2 through the canopies of densely vegetated regions. The global scale variability of H2 and δ[DH2] is well represented by the updated model. H2 is slightly overestimated in the Southern Hemisphere because too little H2 is removed by dry deposition to rainforests and savannahs. The variability in H2 over Europe is further investigated using a high‐resolution model subdomain. It is shown that discrepancies between the model and the observations are mainly caused by the finite model resolution. The tropospheric burden is estimated at 165±8 Tg H2. The removal rates of H2 by deposition and photochemical oxidation are estimated at 53±4 and 23±2 Tg H2/yr, resulting in a tropospheric lifetime of 2.2±0.2 year.
Edinburgh Research Explorer Bonobo personality

The study described in this chapter examines whether individual differences in six rating-based bonobo personality dimensions---Assertiveness, Conscientiousness, Openness, Attentiveness, Agreeableness, and Extraversion---are related to sex and age and behaviors and dominance. To these ends, the study tested predictions based on previous studies of human and chimpanzee personality, and bonobo behavior and socioecology. Sex and age differences in Assertiveness, Openness and Extraversion and correlations between these personality dimensions and behavior were consistent with our predictions. Conscientiousness showed associations with observed behaviors but requires further investigation as sex and age effects differed from those reported in humans and chimpanzees. Agreeableness and Attentiveness showed few associations with age, sex, and behaviors, indicating the need to further investigate validity of these factors. This study shows that personality dimensions in bonobos are correlated with sex, age and behaviors in ways that are consistent with what is known for bonobos and their socioecology.