Miracle-dz/UniFAR-FTUs huggingface dataset:
Causal Implications of Performance Management for Strategic Control

In contrast to conventional concepts of management accounting, which are limited to measuring the value realization of firms, the research field of performance measurement and management explicitly focuses on the managerial process of creating value. This process should be analyzed and subse-quently reconstructed in the form of cause-and-effect relationships. Such relationships consist of causes, effects and causal attributions. In management science cause-and-effect-relationships can not be detected and identified as “ontological truth”. They can only be reconstructed on the basis of individual knowledge and individual decisions on the explanation power of available statistical data. Causal enlargement of the value creation task - as induced by the concept of performance measurement and management - affects the function of strategic control. Its causal reinterpretation requires generating causal information and reconstructing cause-effect relationships underlying the strategic management process. The adequacy of these relationships should be systematically reflected within the framework of a meta-control, which is developed as a subfunction of strategic control in the following. Meta-control can protect strategic management against control deficits of the classical single loop and double loop learning. By implementing a meta-control, possible misinterpretations of the causal relevance of events and circumstances, e.g. based on logical implications or spurious correlations, can be reduced. With such a support the efficiency and effectiveness of performance measurement and management can be ensured.
Fermentation Condition and Quality Evaluation of Pineapple Fruit Wine

This research investigated the impact of the concentration of pineapple juice on the characteristics of pineapple wine during fermentation with Saccharomyces cerevisiae var. burgundy. Three ratios of fresh pineapple juice to water were mixed to obtain three treatments, which were T1—2:1, T2—1:1, and T3—1:2. The °Brix and pH of all pineapple juice and water ratios were adjusted to 25 and 4, respectively. The results showed that changes in alcohol, pH, Total Soluble Solids (TSS), Total Titratable Acidity (TAA, as citric acid), and Volatile Acidity (VA, as acetic acid) during the 10-day fermentation among three treatments were significantly different. The highest alcohol content was obtained from the 2:1 with values of 10.71% (v/v). The mixed ratio at 1:1 and 1:2 obtained the alcohol value of 9.61 and 8.35% (v/v), respectively. After ten days of fermentation, TSS, pH values, TAA, and VA were in the range of 9.7–13 °Brix, 3.56–3.82, 0.384–0.448, and 0.0013–0.0016, respectively. However, the appearance, aroma, and taste of all ratios were not significantly different. Sweetness and overall liking, wine with pineapple juice/water ratio at 2:1 had the highest score (p ≤ 0.05). The total antioxidant activities determined by DPPH and total phenolic content were 0.91 mmol/L TE and 365.80 mg/L GAE, respectively, as confirmed by FTIR spectral analyses.
Selective SGLT2 Inhibitor’s Estimation and Validation from Galenical Form by RP-HPLC Method

Aim: The recent analysis is required to do novel and simple, sensitive, precise, efficient, instant and reproducible reverse phase high performance liquid chromatography (RP-HPLC) method for estimation of antidiabetic drug in the unit dosage form. Validation of this method is also planned to make it suitable for the actual use. Study Design: Department of Pharmaceutical Chemistry, Datta Meghe Institute of Medical Sciences deemed to be university, Wardha in collaboration with Balkh university, Mazar-e-sharif, Afghanistan between August 2021 and December 2021. Methodology: In that article develop the method and validate it by estimation of antidiabetic drugs in solid dosage form by RP-HPLC, by using System suitability test, Repeatability, Precision studies (Intra-day and Interday/Intermediate), Linearity/Calibration studies, Robustness, Force degradation, Specificity, Drug recovery/accuracy studies. Results: as per ICH guidelines, the performance if system suitability in remogliflozin were achieved all guidelines; in that, tailing factor (T),separation factors(α),theoretical plates(N),capacity factor (k’), resolution (R) and RSD (%). The validated stress degradation studies under thermal, oxidative, alkali and acid, in few degradation products for remogliflozin (REM). Conclusion: From the results we conclude that, this novel technique which validated for exploration by reverse phase high performance liquid chromatography (RP-HPLC) should be used for routine quality control of remogliflozin (REM) prediction from developed formulation.
Robust multi-criteria design optimization in building design

This paper’s contribution is to increase the ability to predict the impact of design variables using statistical sensitivity analysis on top of building performance simulation (BPS), and based on this find Pareto optimal solutions. To perform the optimisation an evolutionary multi-objective optimisation algorithm (SMS EMOA) was equipped with robustness estimation/uncertainty handling. To allow the optimisation under uncertatiny, Kriging metamodels are used. The design optimisation of an office building located in the Netherlands serves to validate the method. The building is an ideal case study as it combines spacial flexibility (in terms of the office layout) and function.
Control of a 6-DOF Parallel Manipulator through a Mechatronic Approach

This paper shows that a hierarchical architecture, distributing several control actions in growing levels of complexity and using resources of reconfigurable computing, enables one to take into account the ease of future modifications, updates and improvements in robotic applications. An experimental example of a Stewart—Gough platform control (a platform applied as the solution to countless practical problems) is presented using reconfigurable computing. The software and hardware developed are structured in independent blocks. This open architecture implementation allows easy expansion of the system and better adaptation of the platform to its related tasks.
Emergent Cesarean Delivery in a Patient With Freeman-Sheldon Syndrome Complicated by Preeclampsia, Acute Pulmonary Embolism, and Pulmonary Edema: A Case Report

Freeman-Sheldon syndrome (FSS) is an exceedingly rare congenital disorder with an unspecified prevalence. FSS is caused by a mutation in the embryonic skeletal muscle myosin heavy chain 3 gene. Patients may have facial abnormalities that put them at risk of difficult airway intubation. These facial abnormalities include micrognathia, macroglossia, high-arched palate, prominent forehead, and mid-face hypoplasia. Additionally, skeletal abnormalities such as joint contractures, scoliosis with resultant restrictive lung disease, and camptodactyly (bent fingers) can be noted. These features played an important role in the anesthetic management of our FSS patient. Perioperative planning and optimization were crucial in her anesthetic management as she underwent an urgent cesarean section due to preeclampsia with severe features.
Examination of text's lexis using a Polish dictionary

This paper presents an approach to compare and classify books written in the Polish language by comparing their lexis fields. Books can be classified by their features, such as literature type, literary genre, style, author, etc. Using a preassembled dictionary and Jaccard index, we managed to prove a compact hypothesis concerning similar books. Further analysis with the PAM clustering algorithm presented a lexical connection between books of the same type or author. Overall static behaviour of similarities of any particular field on one side and some anomalous tendencies in other cases suggest that recognition of other features is possible. The method presented in this article allows drawing conclusions regarding the connection between any arbitrary books based solely on their vocabulary.
The case of implementing innovative total quality function deployment for preventing the sticking of the latching star in electronic switches

The modern competitive market scenario insists on satisfying customers by integrating innovations with quality. In order to contribute in this direction, this article proposes a technique named as ‘innovative total quality function deployment’ (ITQFD). First, the connection between total quality management (TQM) and innovation is appraised by referring to the literature. Then the theory of designing ITQFD is described. The implementation aspects of ITQFD have been appraised by reporting a study conducted in an Indian electronics switch manufacturing company. This study considered the application of ITQFD for preventing the occurrence of a problem of the latching star getting stuck in electronic switches. After the completion of this study, feedback was received from the ITQFD team members. The analyses of the results of this feedback revealed the practical compatibility of ITQFD and the need for its further development and refinement.
Effect of Tillage and Crop Rotation on Cereal Crops Yield in the Urals of the Nonblack Earth Zone of Russia

— Proper selection of tillage system is important to increase yields. The work purpose is to assess the effectiveness of three different crop rotation and tillage systems combined with the chemistries use and repetitive sowing methods on spring wheat productive capacity and technology properties of its grains under natural conditions of the Urals in the nonblack earth zone of Russia. The study's objectives included studying the effectiveness of tillage systems in the region's conditions, evaluating the need for the use of chemicals, assessing the impact of each of the factors: meteorological conditions, soil fertility, agrotechnology, and intensification methods on wheat yield indicators. A comprehensive approach is used throughout this work. The study was carried out in 2006-2019 in the forest-steppe region of the Southern Urals (Ural Federal District of the Russian Federation). An experiment involving three influencing factors was performed: Factor 1 – the tillage system in crop rotation; Factor 2 – the chemical methods use; Factor 3 – the preceding crop presence. An inverse relationship was found between spring wheat productivity and weed share (Pearson correlation -0.83). There was a negative correlation between the distance from fallow to the plants' proportion affected by fungal rot. Their number has multiplied by more than 1.7. Depending on the preceding crop, the average yield for fallow wheat was 2.94 t per 1 ha, and for the third wheat after fallow, 1.44 t per 1 ha. The study bridged the lack of knowledge in the established task of increasing wheat yields in the Urals steppe forest territories. The three most important factors influencing wheat grain yield and quality are: 1) combined use of chemicals and fertilizers (45% contribution), availability of the forecrop, meteorological and climatic conditions, and tillage system. Consequently, the yield of spring wheat is related to the level of modern agricultural technologies development, particularly on the level of intensification required. Future similar studies should create a unified spring wheat database and allow the ability to adjust performance indicators depending on areas with different climatic conditions.
Prevalence of Anxiety and Depression in Patients With Multiple Sclerosis in Saudi Arabia: A Cross-Sectional Study

Introduction Multiple sclerosis (MS) is a chronic disease of progressive demyelination in the central nervous system and carries a significant risk for depression and other psychological difficulties associated with low quality of life. There is a paucity of data on the prevalence of anxiety and depression in Saudi Arabia among patients with MS. We conducted a cross-sectional study to determine the prevalence of anxiety and depression in Saudi Arabia among patients with MS by age, disease severity, compliance to medication, and social support. Methods This cross-sectional study measured the prevalence of anxiety and depression in 184 adult patients with MS. The patients were selected through a random sampling method from a pool of MS societies in Saudi Arabia. The participants completed self-administered questionnaires that included demographic variables. The participants also completed the Patient Health Questionnaire-9 (PHQ-9) and the General Anxiety Disorder-7 (GAD-7) questionnaire. Results Depression was detected among 139 (75.5%) patients with MS, with most participants having mild depression (31%). More women (83.1%) experienced depression than men (62.1%; p = 0.002). Anxiety disorder was present in 123 (66.8%) patients with MS, and most had mild anxiety (n = 56; 30.4%). Conclusion We found a very high rate of depression and anxiety among patients with MS in Saudi Arabia. Our results highlight the need for periodic screening and examination of patients with MS by psychiatrists to facilitate the early detection and treatment of these comorbidities, potentially improving patient quality of life and health outcomes.
Water Extract of Fritillariae thunbergii Bulbus Inhibits RANKL-Mediated Osteoclastogenesis and Ovariectomy-Induced Trabecular Bone Loss

Fritillariae thunbergii bulbus has been widely used to treat symptoms of coughs and airway congestion in the chest due to pathological colds and damp phlegm in traditional Chinese medicine. Despite its long history of traditional use, its pharmacological activities on osteoclastogenesis and osteoporosis have not been evaluated. This study investigated the effects of the water extract of Fritillariae thunbergii bulbus (WEFT) on osteoclast differentiation in bone marrow-derived macrophage cells and on ovariectomy (OVX)-induced osteoporosis in mice. We found that WEFT significantly inhibited osteoclastogenesis by downregulating the receptor activator of the NF-κB ligand (RANKL) signaling-induced nuclear factor of activated T-cells cytoplasmic 1 (NFATc1) expression. In an OVX-induced osteoporosis model, WEFT significantly prevented the OVX-induced trabecular loss of femurs, accompanied by a reduction in fat accumulation in the bone marrow and liver. In addition, WEFT significantly prevented weight gain and gonadal fat gain without recovering uterine atrophy. Using ultrahigh-performance liquid chromatography-tandem mass spectrometry, seven alkaloids (peimisine glucoside, yibeissine, peiminoside, sipeimine-glucoside, peimisine, peimine, and peiminine) were identified in WEFT. The results of this study suggest that WEFT can be a potential pharmacological candidate to reduce menopausal osteoporosis and menopause-related symptoms, such as fat accumulation.
MIF-2/D-DT is an atypical atherogenic chemokine that promotes advanced atherosclerosis and hepatic lipogenesis

Atherosclerosis is the underlying cause of cardiovascular diseases (CVDs) such as myocardial infarction and ischemic stroke. It is a lipid-triggered chronic inflammatory condition of the arterial vascular wall that is driven by various inflammatory pathways including atherogenic cytokines and chemokines. D-dopachrome tautomerase (D-DT), also known as macrophage migration inhibitory factor-2 (MIF-2), belongs to the MIF protein family, which is best known for its pathogenic role in a variety of inflammatory and immune conditions including CVDs. While MIF is well known as a promoter of atherogenic processes, MIF-2 has not been studied in atherosclerosis. Here, we investigated atherosclerosis in hyperlipidemic Mif-2−/−Apoe−/− mice and studied the role of MIF-2 in various atherogenic assays in vitro. We found that global Mif-2 deficiency as well as its pharmacological blockade by 4-CPPC protected against atherosclerotic lesion formation and vascular inflammation in models of early and advanced atherogenesis. On cellular level, MIF-2 promoted monocyte migration in 2D and 3D and monocyte arrest on aortic endothelial monolayers, promoted B-cell chemotaxis in vitro and B-cell homing in vivo, and increased macrophage foam cell formation. Dose curves and direct comparison in a 3D migration set-up suggest that MIF-2 may be a more potent chemokine than MIF for monocytes and B cells. We identify CXCR4 as a novel receptor for MIF-2. The evidence relies on a CXCR4 inhibitor, CXCR4 internalization experiments, MIF-2/CXCR4 binding studies by yeast-CXCR4 transformants, and fluorescence spectroscopic titrations with a soluble CXCR4 surrogate. Of note, Mif-2−/−Apoe−/− mice exhibited decreased plasma cholesterol and triglyceride levels, lower body weights, smaller livers, and profoundly reduced hepatic lipid accumulation compared to Apoe−/− mice. Mechanistic experiments in Huh-7 hepatocytes suggest that MIF-2 regulates the expression and activation of sterol-regulatory element binding protein-1 and −2 (SREBP-1, SREBP-2) to induce lipogenic downstream genes such as FASN and LDLR, while it attenuated the activation of the SREBP inhibiting AMPK pathway. Studies using receptor Inhibitors showed that SREBP activation and hepatic lipoprotein uptake by MIF-2 is mediated by both CXCR4 and CD74. Lastly and in line with a combined role of MIF-2 in vascular inflammation and hepatic lipid accumulation, MIF-2 was found to be profoundly upregulated in unstable human carotid plaques, underscoring a critical role for MIF-2 in advanced stages of atherosclerosis. Together, these data identify MIF-2 as a novel atherogenic chemokine and CXCR4 ligand that not only promotes lesion formation and vascular inflammation but also strongly affects hepatic lipogenesis in an SREBP-mediated manner, possibly linking atherosclerosis and hepatic steatosis.
Electrospray Deposition of Cellulose Nanofibers on Paper: Overcoming the Limitations of Conventional Coating

While the potential of cellulose nanofibers to enhance the mechanical and barrier properties of paper is well-known, there are many uncertainties with respect to how to apply them. In this study, we use not only bulk addition of micro-/nanofibers and bar coating with oxidized nanofibers, but also a combination of these and, as a novel element, electrospray deposition of nanofiber dispersions. Characterization involved testing the strength of uncoated and coated paper sheets, their resistance to air flow, their Bendtsen roughness, and their apparent density, plus visualization of their surface and cross-sections by scanning electron microscopy. As expected, bulk addition to the unrefined pulp was sufficient to attain substantial strengthening, but this enhancement was limited to approximately 124%. Following this, surface addition by bar coating improved air resistance, but not strength, since, as applying nanocellulose at high consistency was technically unfeasible, this was performed several times with detrimental drying stages in between. However, replacing bar coating with electrospraying helped us overcome these apparent limitations, producing enhancements in both barrier and tensile properties. It is concluded that electrosprayed nanofibers, owing to their uniform deposition and favorable interactions, operate as an effective binder between fibers (and/or fines).
Effects of elevated-temperature bias stressing on radiation response in power VDMOSFETs

The effects of pre-irradiation elevated-temperature bias stressing on radiation response of power VDMOSFETs have been investigated. Larger irradiation induced threshold voltage shift in stressed devices and considerable mobility reduction in unstressed devices have been observed. The underlying changes of gate oxide-trapped charge and interface trap densities have been calculated and analysed in terms of the mechanisms responsible for pre-irradiation stress effects.
Filtering Antenna Synthesis Based on Characteristic Mode Theory

This paper developed a topology synthesis method based on characteristic mode theory (CMT) for design of filtering antenna. Realization mechanism of radiation nulls of the antenna has been revisited and related to the characteristic fields and characteristic currents in the CMT. Two kinds of the methods based on the characteristic fields and the characteristic currents have been proposed to design the filtering antennas. Combined with the non-dominated sorting genetic algorithm-II (NSGA-II), a CMT-based optimization procedure for the topology structure has been presented. With the proposed optimization algorithm, two filtering antennas without and with the consideration of the feeding port are designed, respectively, to achieve the radiation nulls at lower and upper band edges. For demonstration, the two proposed filtering antennas have been fabricated and measured. Good agreement between the simulated and measured results are observed to show the effectiveness of the proposed optimization design method for the topology structures with the filtering responses.
Efficient Modeling of On-Body Passive UHF RFID Systems in the Radiative Near-Field

A novel method is presented to accurately determine the operational range of an on-body, passive ultra-high-frequency (UHF) radio-frequency identification (RFID) system operating in the radiative near-field, based on its far-field radiation patterns. To this end, an efficient algorithm based on 3-D multipole expansion of the electromagnetic fields is formulated. By combining the new operator with the simulated or measured stand-alone far-field radiation patterns of the on-body RFID system, a comprehensive and accurate range determination is obtained. Compared with commercial software tools and measurements, we prove the accuracy and improved speed of the novel technique.
Independent marginal losses with application to locational marginal price calculation

A new kind of power system marginal loss (or loss sensitivity) for nodal MW/Mvar is developed. First the electricity transmission loss is expressed in terms of source currents. It is thus an analytical function. Then the marginal loss with respect to source current is derived based on calculus and vector algebra. Using each source/load power represents its nodal injection current, the marginal loss with respect to source current is then transformed into the marginal loss with respect to source/load power. The new kind of marginal loss is based on load flow solution. It is exact in algorithm and independent of reference bus, thus called independent marginal loss (IML). The IML exactly leads to double collection of actual system loss. It makes loss components of locational marginal price small in spatial fluctuation compared to the existing marginal losses. Numerical examples including the IEEE 118-bus and PJM [Note 1] 5-bus systems are presented to demonstrate the calculation and effectiveness of the IML.