Miracle-dz/UniFAR-FTUs huggingface dataset:
Implicated in the Induction of Apoptosis Segregation of Bad from Lipid Rafts Is

Many molecules relocate subcellularly in cells undergoing apoptosis. Using coimmunoprecipitation experiments we demonstrate that Bad is not associated to 14-3-3 protein, suggesting a new mechanism for the control of the proapoptotic role of Bad. Here we show, by confocal microscopy and cellular fractionation, that Bad is attached to lipid rafts in IL-4-stimulated cells and thymocytes while associated with mitochondria in IL-4-deprived cells. Disruption of lipid rafts by methyl- (cid:1) -cyclodextrin treatment induces segregation of Bad from rafts, which correlates with apoptosis. Our results suggest that the interaction of Bad with rafts is a dynamic process regulated by IL-4 and involved in the control of apoptosis. The Journal of Immunology, 2002, 168: 3387–3393. poptosis is a highly conserved and essential feature of de-velopment and homeostasis in higher organisms. Progress has been made in identifying extracellular, intracellular, and cell surface molecules that regulate apoptosis. Interestingly, positive and negative regulators have been identiﬁed at each level. The Bcl-2 family proteins act as a decision point in the apoptotic pathway. The family is divided into two functional groups: antiapoptotic members and proapoptotic members, including the BH3-only member Bad, which promote apoptosis (1). Bad shares identity only in the BH3 domain and forms heterodimers with Bcl-2 and Bcl-x. Upon stimulation of cells with IL-3 and NGF, Bad becomes serine phosphorylated, resulting in association with 14-3-3 protein (2, 3). It has been shown that the association of 14-3-3 protein with Bad is dependent on serine 155 phosphorylation of Bad. In agreement, IL-2-stimulation of a
Effectiveness of Agile Development Frameworks with Respect to Testing

Software Development Life Cycle models are used as the basis to design software applications. In these models, there exists some tribulations and to overcome these defects, agile models are presented. The mature software applications of agile development utilize both iterative and incremental style. It can be viewed as a response against conventional procedural activity. It is viewed not as to meet the volatility and varying situations but as the modern business ethics for software development. By examining and exploring the agile models, it has been found that efficiency of agile models can be improved. This research investigates the agile frameworks (DSDM and LSD) in terms of testing. It also examines that the effectiveness of dynamic systems development model (DSDM) from testing perspective. The results show the performance of DSDM agile framework and the estimated efficiency of this framework.
Fixing the Cloud Forensic Problem with Blockchain

—Many cloud users are heading into a potentially dev-astating regulatory disaster zone. A major unresolved cloud issue, namely the cloud forensic problem, this is likely to mean many cloud users will be unable to be compliant with the new EU General Data Protection Regulation. We consider the possible use of blockchain, a cryptocurrency based mechanism, to address the as yet unsolved cloud forensic problem. We believe that the underlying blockchain could be adopted to provide a robust mechanism for ensuring that cloud forensic and audit trail records can be securely maintained. This would ensure that cloud users would in turn be able to ensure they are compliant with the new EU General Data Protection Regulation, thus minimising their exposure to punitive levels of ﬁnes. We analyse the key risks in cryptocurrencies, namely the operational risk, market risk and cross contamination risk associated with co-movement of cryptocurrencies with other asset forms, using the most predominant and oldest of those, Bitcoin, to provide an example of how removing these risks might provide a far more effective solution to the cloud forensic problem. Our contribution is to demonstrate how this might be done, and by removing the incentive for attackers, to provide a much higher level of compliance with the EU General Data Protection Regulation for cloud users.
Studies on the growth, survival and production of endangered mahseer, Tor putitora (Hamilton, 1822) at different stocking densities in primary nursing

The research work was conducted in six nursery ponds of 0.01 ha each with 4 days old mahseer, Tor putitora spawn at three different stocking densities viz., 1.50, 1.75 and 2.00 million spawn/ha each having two replicates. Fries were fed same diet of MEGA fish feeds in three different treatments containing 40.57% crude protein (pre-nursery feed) for the first 14 days and 35.52% crude protein (nursery feed) for the second 14 days. The feeding rate was produced in T3 (1103700±10608) than T1 (945675±9320) and T2 (1056650±10314), respectively. But the simple cost benefit analysis showed that higher net benefits were obtained in T2 (TK. 13, 09,968) where the ponds stocked with 1.75 million spawn/ha. Hence, it seems that, among the three tested stocking densities, 1.75 million spawn/ha is the most efficient stocking density for primary nursing of mahseer
Deteksi Covid-19 pada Citra Sinar-X Dada Menggunakan Pre-Training Deep Autoencoder Covid-19 Detection on X-Ray Images using Deep Autoencoder as Pre-Training

Covid-19 detection generally uses laboratory tests with the RT-PCR method to get accurate results. Unfortunately, this test takes a long time, which is around 24 hours to get the results. Apart from using the RT-PCR test, several studies have shown that detection using X-ray images performs fairly accurate results with a faster prediction time. X-ray images that are constructed by grayscale color have different characteristics compared to the image in common, thus experiments were carried out in this study focused on the training of the X-ray image classification model from scratch. But often a model that is trained without pretraining causes the model to not achieve good performance. One form of pretraining method that can be used is by incorporating an unsupervised autoencoder as a model for image reconstruction. In this study, training using pretraining autoencoder achieved the best accuracy of 81.78% with the addition of the CutMix method, color manipulation, and rotation as augmentation. We also showed that adding autoencoder pretraining can increase accuracy consistently by up to 2.58% in the model trained from scratch.
High Performance Computing for Stability Problems

In this work we examine two kinds of applications in terms of stability and perform numerical evaluations and benchmarks on parallel platforms. We consider the applicability of pseudospectra in the field of hydrodynamic stability to obtain more information than a traditional linear stability analysis can provide. We present parallel computational techniques as well as evaluations of pseudospectra of complex flow processes. In the field of nuclear engineering we treat the criticality problem which describes the crucial criteria for the stability of a nuclear reactor. For the resulting eigenvalue problem we highlight the Davidson method as an attractive alternative to the so far widely used power method.
Evaluation of different observation methods of the unknown points using three points resection

In the current times, landscape works in general, and locating points in particular, depend on modern software and survey techniques, since they adopt AI (artificial intelligence) in calculations, thus the results are better if compared to manual calculations which have errors and mistakes. Here, the need to invent methods to check the accuracy of results has emerged, in order to reduces mistakes and errors. Additionally, these methods are adopted to find the unknown coor-dinates or check the calculated coordinates for those points using different methods, whether they were traditional or use the modern survey devices. The process of calculating the coordinates with the use of engineering drawing featured by the dependence on pixels when they locate any point on the drawing screen, so, it is a very accurate method compared to visual devices and manual calculations. And depending on the above concept, the research depended three known points, and the unknown location of a point was found through these points using (Resection) method. The point was located in three different locations and its position was calculated using four different methods (man-ual cadastral computations, modern devices, engineering drawing software and websites). The results obtained from the three methods were compared in the end of the research, the comparison showed that the use of (manual cadastral computations), which depends the accuracy of 3 ranks after comma (millimeters) in calculations and for distance of approximately half kilometer between the known points and the unknown point, caused various errors among the four methods, while the methods that depend on software and websites gave a great match in their coordinates. The reason behind that was excluding the distance calculation as in manual and instruments methods. It was shown that distance and distribution of points play an important role in locating the unknown point accurately. Also it’s shown that the use of devices and manual calculations are not proportional for finding precise results, where one of them was better than the other if right steps are followed.
CINNAMON: AN IMPERATIVE SPICE FOR HUMAN COMFORT

Cinnamon is a spice that has ancient origins and is popularly used as flavorings, as a condiment and in cooking. Cinnamon is also known to provide various medicinal benefits that include lowering of blood cholesterol, for diabetes. Cinnamon is obtained from the bark of the Cinnamon tree. The importance of cinnamon in cookery and medicine has been known since time immemorial, which is evident from the fossil remains that interpret its cultivation in ancient times. Today, It’s not only known for as a strong flavored spice, but it has gained tremendous applications in therapeutic intervention. The bark itself is used for extracting essential oil. As far as cinnamon nutrition is concerned, it contains more than 80 nutrients, beneficial for proper functioning of the body. The unique aroma and pungency of cinnamon are attributed to the compounds cinnamaldehyde and cinnamic aldehyde. Giving due importance to the health benefits of cinnamon, rigorous studies have been done regarding the nutrition facts. Low in cholesterol, saturated fats, sugar, and sodium, It’s an excellent flavoring ingredient for people with heart related problems. Cinnamon contains polyphenols, which are natural antioxidants, that help in regulating blood sugar levels. Certain compounds present in cinnamon stimulate the insulin receptors and thus help the body to use up glucose in the right way. Studies have shown that cinnamon can prove beneficial for those who suffer from diabetes, especially type 2 diabetes. Cinnamon improves insulin resistance, that helps in weight control. This explains the use of cinnamon for weight loss. The total calorie content in 6.8 g of cinnamon is 17. Out of this, only 1 calorie is contributed by fats (total fat content is 0.2 g per 1 tablespoon) and zero % from saturated fats. Overall, It’s good for health conscious people. The amount of carbohydrates in 1 tablespoon serving size is approximately 5.5 g. Unlike other carbohydrate containing food items, it shows a negligible amount of sugar (only 0.1g per 1 tablespoon). The high %age content of dietary fiber (3.6 g in 1 tablespoon) also makes it a preferred spice among people having digestive problems. Using it regularly will reduce indigestion, constipation, and intestinal disorders. The concentration of protein in cinnamon is relatively low, as compared to that of calcium, iron, and dietary fiber content. Serving 6.8 g of the same will provide you 0.3 g proteins. Needless to say, you get proteins from other food ingredients. So, It’s not at all a concerning issue. It’s good source of calcium and iron; having 1 tablespoon of cinnamon is sufficient to yield 14 % calcium and 31 % iron of the daily requirements of an adult. Nevertheless, the requirements may vary slightly as per your calorie needs. It also contains high amounts of vitamin A and C along with minerals like Zn, K, Mg, and Mn. A 6.8 g serving provides 20 % vitamin A and 12 % vitamin C of the daily requirements of an adult.
DNA barcoding through mitochondrial CO1 Identification, divergence and phylogenetic coding through mitochondrial CO1 Identification, divergence and phylogenetic coding through mitochondrial CO1 gene: Fish Identification, divergence and phylogenetic studies

oxidase 1 variabilitymethods variability in barcodingfor used to Specifiedused for the lay off the identification method through more reliabl Neighbor Joining tree based on the Kimura 2 Parameter method done systematically phylogenetic tree with relationships among their speci bunching under the same tree node while differing species clustered under distinct nodes with no exemptions. Abstract DNA barcoding is used to identify particular specie oxidase 1 (CO1) mitochondrial DNA sequence. It is also variability between species and its polymorphism. methods based on maximum likelihood and neighbourhood variability in sequence and taxonomical classification used to craft sequence contour of identified against unidentified Specified marker/tag of mitochondrial cytochrome C used for the species identification purpose. Usefulness lay off the divergence degree among species. Compare to identification method through external or visible morphology, barcoding is more reliable. Computation of genetic distances and Neighbor Joining tree based on the Kimura 2 Parameter method done systematically. Analysis of evolutionary tree stood clearly by making phylogenetic tree with relationships among their speci bunching under the same tree node while differing species clustered under distinct nodes with no exemptions. Study findings concluded Cytochrome C oxidase 1 used as a milestone to species at molecular level, its similarity and divergence among the related cies.
An HSC/battery energy storage system‐based regenerative braking system control mechanism for battery electric vehicles

This paper proposes a novel hybrid energy storage system (HESS) for the regenerative braking system (RBS) of the front‐wheel induction motor‐driven battery electric vehicle. The HESS is an amalgamation of multiple hybrid supercapacitors (HSCs) and lithium‐ion battery cells. An artificial neural network (ANN)‐based RBS control mechanism was used to optimize the switching scheme of the RBS's three‐phase inverter and the vehicular breaking force distribution. In the regenerative braking mode, the ANN‐based HSC/battery RBS transferred the braking energy to be stored in the HSC and, upon reaching the HSC's maximum safety threshold, then to the battery. In addition, the RBS control mechanism could achieve uniform braking force distribution between the front and rear wheels of the vehicle. Furthermore, our findings revealed that the experimental HSC/battery RBS program enhanced the harvesting of the regenerative braking energy, as was evident from the longer driving distance vis‐à‐vis that of the battery‐only vehicle. The HSC/battery RBS also contributed to improved vehicle acceleration and an extended battery life. © 2018 Institute of Electrical Engineers of Japan. Published by John Wiley & Sons, Inc.
Emissions of H 2 S from Hog Finisher Farm Anaerobic Manure Treatment Lagoons: Physical, Chemical and Biological Inﬂuence

: Hydrogen sulﬁde (H 2 S) from hog operations contributes to noxious odors in the surround-ing environment and can be life-threatening. There is, however, limited understanding of what inﬂuences H 2 S emissions from these farms. Emissions of H 2 S were measured periodically over the course of two years at hog ﬁnisher farms in humid mesothermal (North Carolina, NC, USA) and semi-arid (Oklahoma, OK, USA) climates. Emissions were determined using an inverse dispersion backward Lagrangian stochastic model in conjunction with line-sampled H 2 S concentrations and measured turbulence. Daily emissions at the two lagoons were characterized by low emissions on most days with occasional days of high emissions. Mean annual area-speciﬁc emissions were much lower for the NC lagoon (1.32 µ g H 2 S m − 2 s − 1 ± 0.07 µ g H 2 S m − 2 s − 1 ) than the OK lagoon (6.88 µ g H 2 S m − 2 s − 1 ± 0.13 µ g H 2 S m − 2 s − 1 ). Mean annual hog-speciﬁc emissions for the NC lagoon were 0.75 g H 2 S hd − 1 d − 1 while those for the OK lagoon were 1.92 g H 2 S hd − 1 d − 1 . Emissions tended to be higher during the afternoon, likely due to higher mean winds. Daily H 2 S emissions from both lagoons were greatest during the ﬁrst half of the year and decreased as the year progressed and a reddish color (indicating high populations of purple sulfur bacteria (PSB)) appeared in the lagoon. The generally low emissions at the NC lagoon and higher emissions at the OK lagoon were likely a result of the inﬂuence of wind on mixing the lagoon and not the presence of PSB.
PII: S1010-7940(02)00270-1

Objective: Heart manipulation during OPCAB may cause hemodynamical instability in particular for access to the posterior and lateral walls. The ‘no compression’ technique involves enucleation of the heart without any compression on the cavities, and stabilization of the target area with a suction device. The impact of this technique on hemodynamics is assessed. Methods: In order to analyze a homogeneous group, 26 consecutive patients with triple grafts, one to each side of the heart in the same sequential order (posterior, lateral and anterior wall successively) were selected. Heart rate (HR), mean pulmonary arterial pressure (PAP, mmHg), pulmonary capillary wedge pressure (PCWP, mmHg), mean arterial pressure (MAP, mmHg), cardiac output index (COI, l/min per m), and central venous saturation (SvO2,%) were monitored. A coronary shunt was used for all the anastomoses. Results: HR was stable with baseline value of 60 ^ 10 and the highest value for the anterior wall, 63.6 ^ 8 (P 1⁄4 0:23). PAP and PCWP exhibited their highest increase, when compared with baseline, for the lateral wall, 23.9 ^ 4.7 vs. 20.7 ^ 6.2 (P 1⁄4 0:06), and 17.2 ^ 4.7 vs. 14.9 ^ 5.6 (P 1⁄4 0:16), respectively. MAP, COI and SvO2, exhibited their largest drop, when compared with baseline, for the lateral wall too, 73.1 ^ 9.1 vs. 77.1 ^ 7.5 (P 1⁄4 0:12), 1.99 ^ 0.47 vs. 2.26 ^ 0.55 (P 1⁄4 0:09), and 70.5 ^ 8.4 vs. 74.8 ^ 9.3 (P 1⁄4 0:12), respectively. Conclusions: None of the hemodynamical parameter differed significantly from baseline value for all three territories. While hemodynamics was perfectly maintained during the posterior and anterior walls revascularization, exposure of the lateral wall led to marginal changes only. q 2002 Elsevier Science B.V. All rights reserved.
Synthesis and Photocatalytic Property of N-doped BiVO 4 via Sol-Gel Method Using Corn Stem as Template

: N- doped BiVO 4 photocatalysts (CS-BiVO 4 - x N) were successfully prepared by Sol-Gel method taking the corn stem as template and C 6 H 12 N 4 as N source. The samples were characterized with X-ray diffraction (XRD), X-ray photoelectron spectroscope (XPS), scanning electron microscope (SEM), Fourier infrared spectrum (FTIR), and UV-Vis absorption spectroscope (UV-Vis). The photocatalytic activity were investigated by degradation of methyl oran ge (MO) under visible-light irradiation. The results showed that N doping did not change the crystallinity of the BiVO 4 . The doped N replaced some of O atoms in BiVO 4 and formed the –N–V–O
Influence of Carrot Pulp Fortified with Different Concentrations of Apple Pulp on Blended Jam

The aim of this study was to evaluate various combination and effect of storage period on the quality of carrot apple blended jam at ambient temperature (18-25 °C). The treatments were CA 0 , CA 1 , CA 2 , CA 3 , CA 4 and CA 5 . All the treatments were examined for physicochemical properties i.e., total soluble solids (TSS), pH, reducing sugars (%), percent acidity, non-reducing sugars (%), ascorbic acid (mg/100 g), as well as for sensory properties at fifteen days interval for a total storage period of 90 days. Significant increase (P<0.05) were examined in TSS (67.45-70.40 °brix), acidity (0.64-0.80) and reducing sugars (16.64-27.78). While, significant decrease (P<0.05) were examined in pH (3.63-3.44), non reducing sugars (45.04-27.69), ascorbic acid (7.81-5.52 mg/100 g), colour (7.33-4.35), taste (7.40-4.12), texture (7.22-4.06) and overall acceptability (7.36-4.14). Statistical results concluded that treatment and storage has a significant effect on the quality and stability of carrot pulp and apple pulp blend jam. Results revealed that good quality jam could be prepared with equal amount of carrot and apple pulp, which showed with minimum damage to physiochemical and sensory attributes among the other treatment even after 90 days of storage.
Three Stage Performances and Herding of Domestic and Foreign Films in the Korean Market

This article analyzes film performances in the Korean movie market utilizing three-stage models that incorporate available information in three different stages of the movie life cycle, i.e., at the time of its release, at the end of the first week, and at the end of its life cycle. Based on the premise that the performance of a movie is affected principally by factors of scale, evaluation, and competition, we attempted to ascertain the effects on these factors on performances, and how they differ in different stages. Also, by analyzing domestic and foreign movies released in Korea separately, we were able to compare the different effects of the three factors on the performances of the two categories of movies. Additionally, our movie performance models incorporated herding behavior among the customers. Our results demonstrate that herding is prominently observed after the first week only for domestic movies. In general, the scale factor has been shown to be most important for movie performances in all stages. For foreign films, it is particularly critical for the first week and total performances. Whereas the evaluation factor influences domestic film performance more strongly at the screen choice stage, it affects the performance of foreign films more strongly in the later stages of the life cycle. As compared to foreign films, domestic film performance appears to be more sensitive to the competition factor. We also discuss the effects of covariates such as genre and symbolicity on movie performance.
CNTS AND NHA AS REINFORCEMENT TO IMPROVE FLEXURAL AND IMPACT PROPERTIES OF UHMWPE NANOCOMPOSITES FOR HIP JOINT APPLICATIONS

Nano materials with their unique properties achieve good improvement when they used to reinforce polymer matrix composites. CNTs and nHA were added to matrix of UHMWPE to produce eight nanocomposites by adding four weight fractions (%) involve 1, 2, 3 and 5% of each material. Some mechanical properties were tested in this research include the Flexural strength & Shear strength which indicated that UHMWPE/3%CNTs gave the highest strength followed by UHMWPE/5%nHA. Also the results showed that the highest impact strength was for UHMWPE/3%nHA followed by UHMWPE/3%CNTs. This improvement in these tested properties is due to the filling the pores in nanocomposites compared with pure UHMWPE which has many holes filled by air which decrease the mechanical properties of the later.