Miracle-dz/UniFAR-FTUs huggingface dataset:
Hypoxia-mediated regulation of mitochondrial transcription factors: Implications for hypertensive renal physiology

Kidneys have a high resting metabolic rate and low tissue partial pressure of oxygen due to enhanced mitochondrial oxygen consumption and ATP production for active solute transport. Enhanced mitochondrial activity leads to progressive hypoxia from the renal cortex to renal medulla. Renal tubulointerstitial hypoxia (TiH) is severe in hypertensive rats due to increased sodium reabsorption within their nephrons. Additionally, these rats display increased energy demand and therefore, require healthy mitochondria for adequate salt reabsorption. Hence, we sought to study the regulation of mitochondrial biogenesis and expression of mitochondrial transcription factors (mtTFs, viz. Tfam, Tfb1m and Tfb2m) during hypoxic conditions and in rodent models of genetic hypertension. We report that the expressions of HIF-1 α (hypoxia inducible factor-1 α ), PGC-1 α (peroxisome proliferator activated receptor-γ co-activator-1 α ), mtTFs and OXPHOS proteins are elevated in hypertensive rats as compared to their normotensive counterparts. Additionally, studies in cultured kidney cells show that acute hypoxia augments the expression of these genes. We also observe a positive correlation between HIF-1 α and mtTFs transcripts in human tissues. Furthermore, we report for the first time to our knowledge, that HIF-1 α binds to promoters of Tfam, Tfb1m and Tfb2m genes and augments their promoter activities in NRK52e cells subjected to acute hypoxia. Taken together, this study suggests that acute hypoxia may enhance mitochondrial function to meet the energy demand in renal tubular epithelial cells and in young/pre-hypertensive SHR kidneys.
Prestack depth migration of primary and surface-related multiple reflections: Part I — Imaging

Surface-related multiples (i.e., all seismic waves reflected at the free surface at least once) often severely contaminate seismic recordings. Because conventional imaging techniques require input data that consist of primary reflections only, significant processing effort is commonly dedicated to attenuating multiples prior to migration. On the other hand, surface-related multiples provide additional illumination of the subsurface and, therefore, should not be considered as noise. We present a prestack depth-migration method that allows primary and multiple reflections to be imaged simultaneously. Depth imaging using primary and multiple reflections (DIPMR) involves decomposing the datainto upgoing and downgoing wave constituents, followed by downward extrapolation. Artifacts generated by interference of upgoing and downgoing events not associated with the same subsurface reflection points (crosstalk) are attenuated by using a 2D deconvolution imaging condition. In contrast to existing methods, DIPMR doe.
PHYSICAL REVIEW A 101, 022308 (2020) Single-step implementation of high-fidelity n-bit Toffoli gates

S. E. Rasmussen ,1,* K. Groenland ,2,3 R. Gerritsma ,2 K. Schoutens,2,3 and N. T. Zinner 1,4,† 1Department of Physics and Astronomy, Aarhus University, 8000 Aarhus C, Denmark 2Institute of Physics, University of Amsterdam, Science Park 904, 1098 XH Amsterdam, Netherlands 3QuSoft, Science Park 123, 1098 XG Amsterdam, Netherlands 4Aarhus Institute of Advanced Studies, Aarhus University, 8000 Aarhus C, Denmark
Afterslip (and only afterslip) following the 2004 Parkfield, California, earthquake

An analysis of the first two years of postseismic surface deformations from GPS reveals that afterslip is the only mechanism significantly contributing to postseismic deformation following the 2004 M6 Parkfield, California earthquake. Finite element modeling shows this event to have been too small to significantly stress the lower crust and upper mantle, thus viscoelastic relaxation did not lead to detectable surface displacements. Similarly, coseismically induced pressure changes in the upper crust were not sufficient to induce a measurable poroelastic response. From 10 days to two years after the Parkfield earthquake, postseismic displacements at all GPS stations experience the same characteristic decay time (∼2 weeks). This suggests that only afterslip was activated and the distribution of slip remained unchanged in this time period. Afterslip was found to be broadly distributed in the upper 15 km of the crust and associated with a moment release of much greater magnitude than the coseismic rupture.
Color Image Retrieval Using M-Band Wavelet Transform Based Color-Texture Feature

Feature Extraction algorithm is a very important component of any retrieval scheme. We propose M-band Wavele t Transform based feature extraction algorithm in this paper. The MxM sub-bands are used as primitive features, over which energies computed in a neighborhood are taken as the feature s for each pixel of the image. These features are clustered usi ng FCM to obtain image signature for similarity matching using the Earth Mover’s Distance. The results obtained were compa red with MPEG-7 content descriptor based system and found to be superior.
Narrative Practice: Continuing the Conversations

Michael White's untimely death deprived therapists of a leading light. Here, available for the first time in book form, is a collection of the work he left behind-writings on topics dear to the psychotherapeutic world: turning points in therapy, conversations, resistance and therapist responsibility, couples therapy, and narrative responses to trauma.
Shelf Sedimentation: An Example from the Jurassic of Britain

ABSTRACT The refined biostratigraphic framework that has been developed for Jurassic sediments of northwest Europe enables precise environmental distinctions to be made on a time-equivalent basis. Using such control, it can be demonstrated that shelf sedimentation in the Lower Jurassic (Toarcian) of southern England was dominated by the gradual migration of a large sand bar. Despite the general homogeneity of its detrital sandstones and siltstones, this bar may be subdivided into four principal environments of deposition which include 1) bar (beach and upper shoreface), 2) fore-bar (middle shoreface), 3) back bar, and 4) tidal channel. These environments are distinguished on the basis of qualitative and quantitative textural and compositional criteria: succession of sedimentary structures, bio urbation, grain size, sorting, skewness, and petrography. The bar complex is 150 ft thick, and is transitional downward and southward into condensed limestones and argillaceous siltstones (40 ft average thickness). The limestones are principally intramicrites, the intraclasts being of the same composition as the host sediment (biomicrite), and often display oxidation rims. Such deposits are considered to be of shallow, marine origin. On the other hand, the argillaceous siltstones, which may contain up to 20 percent micrite, represent deeper marine conditions of deposition. The bar complex is succeeded upward and to the north by condensed limestones of variable composition, principally oomicrites, pisomicrites, and biomicrites. These limestones (12 ft average thickness) represent a platform interior sand blanket which was developed under shal ow marine conditions in the lee of the large bar complex. Because 1) new sediment was constantly added to the southward side of the bar, and 2) subsidence did not quite keep pace with sediment supply, the bar was forced to accrete continually in a southward direction, at a rate of 1 mile per 80,000 years. The gradual southward migration of the bar resulted in preservation of vertical sequences which, when completely developed, comprise a basal argillaceous and calcareous facies (the Upper Lias Clay Formation), succeeded by an arenaceous facies (the Upper Lias Sand Formation), and capped by a calcareous facies (the Cephalopod Bed Formation). Sediments comprising these three facies were deposited in two distinct basins of deposition, separated by an east-west trending structural high (the Mendip Axis). Both basins subsided to receive a maximum thickness of some 340 ft of marine sediments. Because of the southward migration of the bar, the southern basin received its major sediment input only after the northern basin had already been filled. The nature and rate of sediment supply remained constant throughout the 6 million years duration of the Toarcian, the principal source being a meta-igneous complex located in the present western approaches to the English Channel.
Digital Image Texture Analysis Using Gray Level and Energy Cooccurrence

In this paper, a new digital image texture analysis method, i.e., gray level and energy cooccurrence image texture analysis method, is presented. According to the method, the two image texture analysis models are designed. They are 3 X 3 no-zero-sum mask model and gray level-difference cooccurrence matrix model. And their texture parameters are calculated by using these models, separately. The satisfactory test results are acquired for classifying the sensing images.
Warm Arctic—cold continents: climate impacts of the newly open Arctic Sea

Recent Arctic changes are likely due to coupled Arctic amplification mechanisms with increased linkage between Arctic climate and sub-Arctic weather. Historically, sea ice grew rapidly in autumn, a strong negative radiative feedback. But increased sea-ice mobility, loss of multi-year sea ice, enhanced heat storage in newly sea ice-free ocean areas, and modified wind fields form connected positive feedback processes. One-way shifts in the Arctic system are sensitive to the combination of episodic intrinsic atmospheric and ocean variability and persistent increasing greenhouse gases. Winter 2009/10 and December 2010 showed a unique connectivity between the Arctic and more southern weather patterns when the typical polar vortex was replaced by high geopotential heights over the central Arctic and low heights over mid-latitudes that resulted in record snow and low temperatures, a warm Arctic—cold continents pattern. The negative value of the winter (DJF 2009/10) North Atlantic Oscillation (NAO) index associated with enhanced meridional winds was the lowest observed value since the beginning of the record in 1865. Wind patterns in December 2007 and 2008 also show an impact of warmer Arctic temperatures. A tendency for higher geopotential heights over the Arctic and enhanced meridional winds are physically consistent with continued loss of sea ice over the next 40 years. A major challenge is to understand the interaction of Arctic changes with climate patterns such as the NAO, Pacific North American and El Niño–Southern Oscillation.
Simulation of the Catalytic Gasification of Banana Biomass in the Production of Hydrogen, Using Glucose as a Model Compound

In the face of the climate change problem caused by fossil fuels, it is essential to seek efficient alternative energies with a lower environmental impact that are derived from renewable resources. Biomass gasification technology continues to generate significant interest in sustainable energy research as an alternative to traditional combustion technology. Gasification involves the thermochemical conversion of raw materials, resulting in a highly valuable gaseous product known as synthesis gas, commonly used as a fuel. Its numerous advantages include the availability of raw materials, the reduction in harmful emission streams, performance, and costs. As this topic gains momentum in the global energy framework, it is imperative to advance the maturity of this technology by addressing its weaknesses, primarily in terms of efficiency. The objective of this project was to investigate the hydrogen production process through the simulation of glucose gasification as a representative compound for biomass. This was achieved by conducting an integrated simulation of glucose gasification, encompassing both the heat transfer in the external system and the conversion of glucose into hydrogen gas, using the results obtained in the external system as initial conditions. Interrelated aspects of this complex process, including heat transfer and the kinetics of the gasification process, were modeled. Glucose was selected as the model compound due to its availability, simplicity, fundamental understanding, reproducibility, comparability, knowledge of reaction pathways, and simplification of mathematical models. The simulation resulted in a H2:CO ratio of 2.2, and molar fluxes were obtained for H2, CO, CO2, CH4, and H2O consistent with those typically observed in the gasification process of organic matter. These models were constructed, laying the foundation for the adaptability of subsequent optimization studies.
Quality Assessment of Tropospheric Delay Estimated by Precise Point Positioning in the Korean Peninsula

Over the last decade, the Global Navigation Satellite System (GNSS) has been increasingly utilized as a meteorological research tool. The Korea Astronomy and Space Science Institute (KASI) has also been developing a near real-time GNSS precipitable water vapor (PWV) information management system that can produce a precise PWV for the Korean Peninsula region using GNSS data processing and meteorological measurements. The goal of this paper is to evaluate whether the precise point positioning (PPP) strategy will be used as the new data processing strategy of the GNSS-PWV information management system. For this purpose, quality assessment has been performed by means of a comparative analysis of the troposphere zenith total delay (ZTD) estimates from KASI PPP solutions (KPS), KASI network solutions (KNS), and International GNSS Service (IGS) final troposphere products (IFTP) for ten permanent GNSS stations in the Korean Peninsula. The assessment consists largely of two steps: First, the troposphere ZTD of the KNS are compared to those of the IFTP for only DAEJ and SUWN, in which the IFTP are used as the reference. Second, the KPS are compared to the KNS for all ten GNSS stations. In this step, the KNS are used as a new reference rather than the IFTP, because it was proved in the previous step that the KNS can be a suitable reference. As a result, it was found that the ZTD values from both the KPS and the KNS followed the same overall pattern, with an RMS of 5.36 mm. When the average RMS was converted into an error of GNSS-PWV by considering the typical ratio of zenith wet delay and PWV, the GNSS-PWV error met the requirement for PWV accuracy in this application. Therefore, the PPP strategy can be used as a new data processing strategy in the near real-time GNSS-PWV information management system.
Velocity and attenuation of seismic waves in two-phase media; Part I, Theoretical formulations

The propagation of seismic waves in two‐phase media is treated theoretically to determine the elastic moduli of the composite medium given the properties, concentrations, and shapes of the inclusions and the matrix material. For long wavelengths the problem is formulated in terms of scattering phenomena in an approach similar to that of Ament (1959). The displacement fields, expanded in series, for waves scattered by an “effective” composite medium and individual inclusions are equated. The coefficients of the series expansions of the displacement fields provide a relationship between the elastic moduli of the effective medium and those of the matrix and inclusions. The expressions are derived for both solid and liquid inclusions in a solid matrix as well as for solid suspensions in a fluid matrix. Both spherical and oblate spheroidal inclusions are considered. Some numerical calculations are carried out to demonstrate the effects of fluid inclusions of various shapes on the seismic velocities in rocks. I.
Thermal state of permafrost and active layer in Central Asia during the international polar year

Permafrost in Central Asian is present in the Qinghai–Tibet Plateau in China, the Tien Shan Mountain regions in China, Kazakhstan and Kyrgyzstan, the Pamirs in Tajikistan, and in Mongolia. Monitoring of the ground thermal regime in these regions over the past several decades has shown that the permafrost has been undergoing significant changes caused by climate warming and increasing human activities. During the International Polar Year, measured mean annual ground temperature (MAGT) at a depth of 6 m ranged from −3.2°C to 0.2°C on the Qinghai–Tibet Plateau and the active‐layer thickness (ALT) varied between 105 and 322 cm at different sites. Ground temperatures at the bottom of the active layer (TTOP) warmed on average by 0.06°C yr−1 over the past decade. In Mongolia, MAGT at 10–15 m depth increased by up to 0.02–0.03°C yr−1 in the Hovsgol Mountain region, but by 0.01–0.02°C yr−1 in the Hangai and Hentei Mountain regions. The increase in permafrost temperatures in the northern Tien Shan from 1974 to 2009 ranged from 0.3°C to 0.6°C. At present measured permafrost temperatures vary from −0.5°C to −0.1°C. The ALT increased from 3.2 to 4 m in the 1970s to a maximum of 5.2 m between 1995 and 2009. Copyright © 2010 John Wiley & Sons, Ltd.
Late Paleozoic tectonic amalgamation of northwestern China: Sedimentary record of the northern Tarim, northwestern Turpan, and southern Junggar Basins

Sedimentary rocks contained in basins adjacent to the Tian Shan provide a long and complex record of the late Paleozoic continental amalgamation of northwestern China, complementing that provided by rocks preserved within the range. This record, which comprises dramatic changes in sedimentary facies, sediment dispersal patterns, sandstone provenance, and basin subsidence rates, broadly supports previous interpretations of a two-part evolution of the Tian Shan: Late Devonian to Early Carboniferous collision of the Tarim continental block with the Central Tian Shan, followed by collision of this combined block with island arcs in the north Tian Shan and Bogda Shan in Late Carboniferous–Early Permian times. The first collision resulted in widespread angular unconformities within the Tarim basin. Continued convergence following the collision created a long-lived flexural foredeep along the northern margin of the Tarim block, which received at least 2000 m of Lower Carboniferous through Lower Permian fluvial and marine sediment derived from the interior of Tarim. Subsequent Early Permian continental extension of the northern Tarim basin resulted in the deposition of interbedded nonmarine siliciclastic sedimentary rocks and mafic to felsicvolcanic rocks. Sandstone within this interval was derived from the paleo–Tian Shan, and is composed predominantly of lithic volcanic grains similar to the rhyolite. In contrast to the Tarim basin, calc-alkaline volcanic rocks and volcanogenic sedimentary rocks dominated Carboniferous and Permian sedimentation in the northern Turpan and northwestern Junggar basins. Volcanic arcs remained active in the North Tian Shan and Bogda Shan through the early Late Carboniferous, depositing a kilometers-thick interval of deep marine sediment-gravity flows in the northwestern Junggar basin. Major arc magmatism ceased in the Late Carboniferous in response to closure of the oceanic basin between the combined Tarim/Central Tian Shan block and the North Tian Shan/Bogda Shan arcs. Upper Carboniferous through Lower Permian rocks in the northwestern Junggar basin compose the sedimentary fill of a bathymetric basin of oceanic depth (on the northern side of the volcanic arcs), culminating in a 1000-m-thick marine regressive sequence. Middle to Upper Permian sandstones were derived from the uplifted paleo–Tian Shan and bear the distinctive provenance imprint of granitic rocks presently exposed within the range. Late Permian subsidence of the Junggar basin accommodated >5 km of nonmarine sediments; however, the cause of this subsidence and its relationship to regional tectonic events remain controversial.
Geopressured Shale and Sealing Effect of Smectite to Illite Transition

Ten shale samples of Frio and Vicksburg (Tertiary) overpressured shales from Brazoria and Hidalgo Counties, Texas, were examined by transmission electron microscopy (TEM) techniques. Initially, illite and smectite (with some mixed-layer component? ) are present in subparallel domains, with smectite packets dominating and providing abundant dislocations for ion transport, supplying avenues that contribute to local permeability. As the transition proceeds, illite packets grow within a shrinking matrix of smectite, dislocations decrease, and pathways for ion transport are restricted. We suggest this development of illite packets and diminished ion transport causes loss of local permeability and a rise in the fluid pressure gradient. As illite packets coalesce, local permeabil ty is increasingly lost; hydraulic continuity with the surface is further restricted and a more efficient geopressure seal is formed. In both Hidalgo and Brazoria Counties, the base of normal hydropressure (0.465 psi/ft or 10.5 kPa/m) coincides with the depth of onset of the smectite-to-illite transition. Geopressure greater than 0.7 psi/ft (15.8 kPa/m) occurs at depths corresponding to 50% illite packets in Brazoria County and 70% in Hidalgo County; in both cases, 0.7 psi/ft (15.8 kPa/m) geopressure occurs prior to the depth at which the transition ceases. These relationships suggest that if the smectite-to-illite transition begins and proceeds to completion, the development of coalescing illite packets during diagenesis will lead to increasing geopressure, with the actual values of illite proportion and corresponding fluid pressure gradient determined by the local geologic setting.
Research on imaging algorithm of target detection based on BD signals

The imaging algorithm of target detection based on BD ( Bei Dou ) signals is studied. The constitutes and principles of detecting system space target are firstly discussed, then the imaging algorithm of target detection based on BD signals are deduced, finally according to some models of detection system working, a correspondence detection imaging are simulated, it is expected to lay some reference values for the application of BD signals in scopes of target detection.
Dynamique du phosphore dans le bassin de la Seine et son estuaire

Cet article presente les bilans de phosphore (P) a l'echelle du bassin de la Seine (74 000 km 2 ) urbanise et agricole. En 2000 les engrais representent 60 % des apports aux sols agricoles (20-25 kgP/ha). Les stocks y apparaissent enormes (1 800-5 000kgP/ha]. Les perte par erosion (0,18-0,59 Kg/ha) et par drainage (0,12 KgP/ha) representent un faible pourcentage de ce stock (< 0,01 %) mais contribuent pour 40-50 % des apports de P dans les bassins agricoles amont et 20 % sur l'ensemble du basssin. Les matieres en sus-pension (MES) s'enrichissent en P d'un facteur 4 entre l'amont et l'aval indiquanr une pression croissante des sources ponctuelles de P le long du reseau hydrographique. La forte reactivite du P y est mise en evidence par une methode isotopique au 32 P. Le transfert des ions P entre les MES et l'eau est mis en equation et introduit dans le modele Riverstralher por tester different scenarii de gestion sur le sous-basin de la Marne, le plus eutrophise. Un bilan des flux de P sortant a l'exutoire de la Seine a Poses est relise. 8 000 tP sont ainsi apportees a l'estuaire de la Seine a 44 % sous forme particulaire en 2000. Les MEX s'appauvrissent d'un facteur 2 dans la zone estuarienne contribuant de facon significative a l'enrichissement de la zone cotiere en phosphore.