Miracle-dz/UniFAR-FTUs huggingface dataset:
Multiphysics methods development for high temperature gas reactor analysis

Gas cooled reactors have been characterized as one of the most promising nuclear reactor concepts in the Generation-IV technology roadmap. Considerable research has been performed on the design and safety analysis of these reactors. However, the codes and methods being used to perform these analyses are not state-of-the-art and are not capable of performing detailed three-dimensional analyses. This paper presents the results of an effort to develop an improved thermal-hydraulic solver for the pebble bed type high temperature gas cooled reactors. The solution method is based on the porous medium approach and the momentum equation including the modified Ergun’s resistance model for pebble bed and energy equation in two temperature model are solved in three-dimensional cylindrical geometry. A preliminary verification was performed by comparing the results with the experiments conducted at the SANA test facility. Various experimental cases are modeled and good agreement is observed. The 3-D thermal-hydraulics code was then coupled to the 3-D spatial kinetics code, PARCS, to perform coupled reactor simulations. The verification of the coupled code system was performed by analyzing the steady state and transient cases of the OECD/NEA PBMR-400 benchmark problem.
Model-Free Radio Map Estimation in Massive MIMO Systems via Semi-Parametric Gaussian Regression

Accurate radio maps will be very much needed to provide environmental awareness and effectively manage future wireless networks. Most of the research so far has focused on developing power mapping algorithms for single and omnidirectional antenna systems. In this letter, we investigate the construction of crowdsourcing-based radio maps for 5G cellular systems with massive directional antenna arrays (spatial multiplexing), proposing an original technique based on semi-parametric Gaussian regression. The proposed method is model-free and provides highly accurate estimates of the radio maps, outperforming fully parametric and non-parametric solutions.
The Microbiota of a Mite Prey-predator System on Different Host Plants Are Characterized by Functional Redundancy and Dysbiosis

Microbiota have diverse roles in the life cycles of their hosts, affecting their growth, development, behavior, and reproduction. Changes in physiological conditions of the host can also impact the assemblage of host-associated microorganisms. However, little is known of the effects of host plant–prey–predatory mite interactions on mite microbiota. We compared the microbial communities of eggs and adult females of the two˗spotted spider mite Tetranychus urticae Koch (Acari: Tetranychidae) and of adult females of the predatory mite Neoseiulus californicus (McGregor) (Acari: Phytoseiidae) on four different host plants (cotton, maize, pinto bean, and tomato) by metabarcoding sequencing of the V3–V4 region of the 16S ribosomal RNA gene (16S rRNA), using the Illumina MiSeq platform. Only the egg microbiota of T. urticae was affected by the host plant. The microbiota of the predatory mite N. californicus was very different from that of its prey, and the predator microbiota was unaffected by the different host plant–prey systems tested. Only the microbiota of the eggs of T. urticae carried Serratia as a high fidelity-biomarker. Biomarker bacteria were also detected in the microbiota of adult females of T. urticae and N. californicus, with different biomarkers in each host-plant species. The microbiota associated with eggs and adult females of T. urticae and adult females of N. californicus differed in their potential contributions to the host mite.
Depression, Anxiety, and Suicidal Ideation in Patients with Atopic Eczema in a Prospective Study in Leipzig, Germany

Background: Atopic eczema (AE) is known to be associated with depression and anxiety. We aimed at investigating the occurrence of selected psychological comorbidities in patients with AE under treatment in our university dermatological department. Methods: Monocentric prospective examination of adult AE patients using PO-SCORAD (Patient-Oriented Severity Scoring of AD), EASI (Eczema Area and Severity Index), POEM (Patient-Oriented Eczema Measure), DLQI (Dermatologic Life Quality Index), LSNS-6 (Lubben Social Network Scale 6), CES-D (Center for Epidemiologic Studies Depression Scale), HADS-D and -A (Hospital Anxiety and Depression Scale), and GAD-7 (Generalized Anxiety Disorder Scale-7) was carried out. We looked for correlations between AE severity and psychosocial comorbidities. Data were compared with age- and sex-matched controls from nonatopic subjects. Statistics: Mann-Whitney U test and Spearman’s rank correlation were used. Results: Eighty-four patients (44 women, median age 35.0 years, range: 19.4–92.8 years) were included. PO-SCORAD was 40.4 [23.4–55.4] (median [interquartile range]), EASI 9.3 [3.4–18.9], POEM 16 [8–24], and DLQI 10 [4–18]. Compared with 161 from the healthy LIFE-Adult cohort controls, our patients with AE had significantly higher scores for HADS, GAD-7, and CES-D (p < 0.001, respectively), but there was no increase in the LSNS score (18 vs. 19; p = 0.067). Within the group of AE patients, there was a significant correlation of the subjective skin severity and the depression and anxiety values: POEM significantly correlated with GAD-7, CES-D, and HADS-A and -D (p < 0.001). PO-SCORAD significantly correlated with GAD-7 and CES-D (p < 0.05). EASI correlated neither with HADS-A or -D nor with CES-D. Patients with suicidal thoughts, plans, or attempts in the last 12 months had significantly more severe AE than those without (POEM 25 [15.3–26] vs. 15 [7–23]; p = 0.013, and PO-SCORAD 51.6 [40.2–63] vs. 20.5 [20.7–52]; p = 0.014). Conclusion: Patients with AE being currently under treatment in our department had significantly increased scores indicating depression and anxiety. Suicidal tendency was increased in patients with severe AE. Key Message: AE patients may develop depression, anxiety, and suicidal ideation. Patient-oriented scores may help identifying high-risk patients.
Development of a Proton-Frequency-Transparent Birdcage Radiofrequency Coil for in Vivo 13C MRS/MRSI Study in a 3.0 T MRI System

A proton-frequency-transparent (PFT) birdcage RF coil that contains carbon-proton switching circuits (CPSCs) is presented to acquire 13C MR signals, which, in turn, enable 1H imaging with existing 1H RF coils without being affected by a transparent 13C birdcage RF coil. CPSCs were installed in the PFT 13C birdcage RF coil to cut the RF coil circuits during 1H MR imaging. Finite-difference time-domain (FDTD) electromagnetic (EM) simulations were performed to verify the performance of the proposed CPSCs. The performance of the PFT 13C birdcage RF coil with CPSCs was verified via phantom and in vivo MR studies. In the phantom MR studies, 1H MR images and 13C MR spectra were acquired and compared with each other using the 13C birdcage RF coil with and without the CPSCs. For the in vivo MR studies, hyperpolarized 13C cardiac MRS and MRSI of swine were performed. The proposed PFT 13C birdcage RF coil with CPSCs led to a percent image uniformity (PIU) reduction of 1.53% in the proton MR images when compared with the case without it. FDTD EM simulations revealed PIU reduction of 0.06% under the same conditions as the phantom MR studies. Furthermore, an SNR reduction of 5.5% was observed at 13C MR spectra of corn-oil phantom using the PFT 13C birdcage RF coil with CPSCs compared with that of the 13C birdcage RF coil without CPSCs. Utilizing the PFT 13C birdcage RF coil, 13C-enriched compounds were successfully acquired via in vivo hyperpolarized 13C MRS/MRSI experiments. In conclusion, the applicability and utility of the proposed 16-leg low-pass PFT 13C birdcage RF coil with CPSCs were verified via 1H MR imaging and hyperpolarized 13C MRS/MRSI studies using a 3.0 T MRI system.
Nonlinear Aeroelastic Methodology for A Membrane-on- Ballute Model with Hypersonic Bow Shock

[Abstract] A nonlinear aeroelastic methodology for inflatable/ballute type structures has been successfully developed for, a heuristic case: a 2D membrane-on-wedge model, and an axisymmetric modeled ballute system (MBS), under hypersonic/supersonic shock waves. Specifically, the nonlinear structural ROM methodology ELSTEP/FAT is extended and validated (based on MSC.Nastran FEM model) to the membrane-on-wedge model and the axisymmetric MBS. The time-accurate GasKinetic BGKX methodology has been developed as the key aerodynamic solver. It has great advantages over current continuum CFD solvers with its solution robustness, one-step computation of pressure and heat flux, and broad range of Knudsen number for hypersonic applications. Nonlinear aerodynamic static deformations at various altitudes have been obtained through a tight coupling between the nonlinear structural ROM and the direct BGKX aerodynamic solver. An efficient aerodynamic ROM has been developed for the undeformed/deformed mean 2D/axisymmetric configurations using a system identification technique with staggered modal inputs. The aerodynamic ROM solutions are found to closely match the direct BGK solutions. ROM-ROM time-domain dynamic aeroelastic analyses reveal significant differences between analyses carried out around the undeformed configuration and around the deformed one. In particular, a decrease in altitude will increase the static deformations which lead to a stiffer behavior with respect to additional small perturbations. Accordingly, a decrease in altitude induces an increased stability, in contrary to aeroelastic solutions for the undeformed configuration. This fundamental observation demonstrates the need to perform tightly coupled steady aeroelastic analyses prior to any stability analysis.
Radial versus Combined Shockwave Therapy in the Management of Proximal Hamstring Tendinopathy: Similar Functional Outcomes in Running Cohort

and achieved similar final scores (62.6 ± 19.7 vs 63.4 ± 21.3; p = 0.812), and nearly all had measured increases of VISA-H with treatment (P < 0.0001). The MCID was met in a majority of patients who received either radial (62.5%) or combined treatment (56.5%). Conclusions. Overall findings suggest radial and combined shockwave treatment with physical therapy exercises can be effective in the management of proximal hamstring tendinopathy in runners.
A Prelim Investigation on Social Media Usage as Risk Communicational Platform for Klang Valley Flash Flood Management

Throughout unprecedented events such as flooding, it is important to stay connected and engaged with one another. There is an increasing trend of flooding occurrences in Klang Valley to date. However, the study of risk communication for flood management, specifically in the region is scarce. Thus, this paper examines the current communication arrangement in the flood management system in Klang Valley, Malaysia which involve various parties; the government, agencies, local authorities and the community. This study aims to explore the usage of social media (SM) as risk communication tool that could be used to maintain engagement within all the participants. Subsequently, elements derived from previous literatures were used in this qualitative study entailing semistructured interviews involving three key informants to unveil the actual issues and barriers for SM usage in flood management. Further, Likert scale questionnaires were used to identify the usability of several SM platforms in flood management. Our main finding highlighted the importance of collaboration and communication using SM in flood management as this can engage the chain of key persons. Thus, this study reveals the relevance of considering SM as a risk communication tool for flood management, where it fits the role as a communication vehicle during all phases of flood management. Results obtained from this study can be used for further work related to social media and flood management.
Differential recognition of opioid analgesics by µ opioid receptors: Predicted interaction patterns correlate with ligand-specific voltage sensitivity

The µ opioid receptor (MOR) is the key target for analgesia, but the application of opioids is accompanied by several issues. There is a wide range of opioid analgesics, differing in their chemical structure and their properties in receptor activation and subsequent effects. A better understanding of ligand-receptor interactions and resulting effects is important. Here, we calculated the respective binding modes for several opioids and analyzed fingerprints of ligand-receptor interactions. We further corroborated the binding modes experimentally by cellular assays. As ligand-induced modulation of activity due to changes in membrane potential was displayed by MOR, we further analyzed the effects of voltage sensitivity of this receptor. With a combined in silico and in vitro approach, we defined discriminating interaction patterns for the ligand-specific voltage sensitivity. With this, we present new insights for interactions likely in ligand recognition and their specific effects on activation of the MOR.
“They Wait until the Disease Has Taking over You and the Doctors Cannot Do Anything about It”: Qualitative Insights from Harambee! 2.0

African immigrants make up a large subgroup of Black/African-Americans in the US. However, because African immigrant groups are typically categorized as “Black,” little is known about their preventative healthcare needs. Differences in culture, life and healthcare experiences between African immigrant populations and US-born people may influence preventive health care uptake. Thus, policymakers and healthcare providers lack information needed to make informed decisions around preventive care for African immigrants. This formative study was conducted among the largest East African immigrant communities in King County, WA. We recruited religious leaders, community leaders, health professionals, and lay community members to participate in thirty key informant interviews and five focus group discussions (n = 72 total), to better understand preventative healthcare attitudes in these communities. Through inductive coding and thematic analysis, we identified factors that impact preventative healthcare attitudes of the Somali, Ethiopian and Eritrean immigrant communities and deter them from accessing and utilizing healthcare. Cultural beliefs and attitudes around preventative healthcare, mistrust of westernized healthcare, religious beliefs/views, intersecting identities and shared immigrant experiences all influence how participants view preventative healthcare. Our results suggest that interventions that address these factors are needed to most effectively increase uptake of preventative healthcare in African immigrant communities.
Analysis of the Causal Relationship of Body Image Factors in Patients with Cancer

Patients with cancer can potentially experience the negative impacts of treatment. Physical conditions due to illness and therapy can affect the patient's body image. This study aims to find a causal model among body image factors of patients with cancer using the S3C-Latent Method. The measurement of body image of patients with cancer used the BIS questionnaire. One hundred and ninety-nine patients with cancer participated in this study. The results showed the existence of causal relationships between behavior to cognitive factors and duration of illness with reliability scores of 0.8 and 0.6, respectively; from gender to affective factors, illness duration, behavior, and cognitive factors with reliability scores of 0.6, 0.8, 0.65, and 1, respectively. There are also causal relationships from age to affective factors, duration of illness, and cognitive factors with reliability scores of 0.8, 0.7, and 0.9, respectively. The results also showed that affective factors are associated with behavior, cognitive factors, and duration of illness, with reliability scores of 1, 1, and 0.9, respectively. The results showed further the association of cognitive factors and illness duration with a reliability score of 1. We expect that the estimated causal model will serve as a scientific reference for medical experts in developing a better intervention such as treatment.
Formulasi dan Evaluasi Masker Wajah Peel-Off Mengandung Kuersetin dengan Variasi Konsentrasi Gelatin dan Gliserin

Kuersetin dapat menjadi salah satu alternatif bahan aktif anti jerawat dan pencegah penuaan dini karena dapat menghambat pertumbuhan bakteri penyebab jerawat Staphylococcus epidermidis dan Propionibacterium acnes dan memiliki aktivitas antioksidan pada konsentrasi 0,05%. Masker wajah peel off adalah salah satu jenis masker wajah yang memiliki keunggulan dalam penggunaannya yaitu mudah diangkat atau dilepaskan seperti membran elastis. Penelitian ini bertujuan untuk menentukan pengaruh penambahan variasi konsentrasi gelatin dan gliserin terhadap sifat fisika dan kimia masker wajah peel off kuersetin. Variasi konsentrasi gelatin yang digunakan adalah10%, 15% dan 20%, variasi konsentrasi gliserin yang digunakan adalah 2%, 6% dan 12%. Evaluasi sediaan masker wajah peel off kuersetin meliputi karakteristik organoleptis (warna, konsistensi, bau), waktu mengering, viskositas, pH, homogenitas, daya sebar dan daya lekat. Data hasil evaluasi sediaan masker wajah peel off kuersetin dianalisis dengan program Design Expert 8.0. 7. dengan desain faktorial dan Kruskal Wallis. Hasil menunjukkan bahwa variasi konsentrasi gelatin dan gliserin secara signifikan mempengaruhi organoleptis, waktu mengering, homogenitas, viskositas, daya lekat dan daya sebar sediaan (p 0,05). Kata Kunci: Masker wajah peel off, kuersetin, gelatin, gliserin
One-carbon pathway metabolites are altered in the plasma of subjects with Down syndrome: Relation to chromosomal dosage

Down syndrome (DS) is the most common chromosomal disorder and it is caused by trisomy of chromosome 21 (Hsa21). Subjects with DS show a large heterogeneity of phenotypes and the most constant clinical features present are typical facies and intellectual disability (ID). Several studies demonstrated that trisomy 21 causes an alteration in the metabolic profile, involving among all one-carbon cycle. We performed enzyme-linked immunosorbent assays (ELISAs) to identify the concentration of 5 different intermediates of the one-carbon cycle in plasma samples obtained from a total of 164 subjects with DS compared to 54 euploid subjects. We investigated: tetrahydrofolate (THF; DS n=108, control n=41), 5-methyltetrahydrofolate (5-methyl-THF; DS n=140, control n=34), 5-formyltetrahydrofolate (5-formyl-THF; DS n=80, control n=21), S-adenosyl-homocysteine (SAH; DS n=94, control n=20) and S-adenosyl-methionine (SAM; DS n=24, control n=15). Results highlight specific alterations of THF with a median concentration ratio DS/control of 2:3, a decrease of a necessary molecule perfectly consistent with a chromosomal dosage effect. Moreover, SAM and SAH show a ratio DS/control of 1.82:1 and 3.6:1, respectively. The relevance of these results for the biology of intelligence and its impairment in trisomy 21 is discussed, leading to the final proposal of 5-methyl-THF as the best candidate for a clinical trial aimed at restoring the dysregulation of one-carbon cycle in trisomy 21, possibly improving cognitive skills of subjects with DS.
Characterization of Thermally Actuated Pole Tip Protrusion for Head-Media Spacing Adjustment in Hard Disk Drives

As the areal density of magnetic disk storage continues to increase and head-disk spacing decreases, contact between the recording slider and the rotating media becomes imminent. In order to predict contact forces, fly-height modulations, and off-track motions, dynamic models are typically used. A critical element of these models is the contact stiffness and damping arising from the interfacial interaction between the slider and the disk. In this paper, we review different models for predicting contact stiffness based on roughness and layered media and then we report experimental data of both contact stiffness and contact damping of typical head-disk interfaces. It is found that the contact stiffness models (based on roughness alone) overpredict the contact stiffness of actual head-disk interfaces by as much as an order of magnitude. Also, it is found that the contact damping ratio is typically few percent and its behavior is substrate dependent. In addition, the effects of a molecularly thin lubricant and humidity on contact stiffness and damping were experimentally investigated and no significant effects were found.
Development of an expanded polystyrene geofoam cover system for pipelines at fault crossings

iii LIST OF SYMBOLS . ix ACKNOWLEDGEMENTS . xiv INTRODUCTION . 1 Chapters 1. REVIEW OF LITERATURE . 3 Manufacturing of EPS Geofoam . 3 Advantages of EPS . 3 Typical Properties and Behavior of Geofoam . 5 Geofoam Use in Buried Applications . 6 Summary of Current Design/Evaluation Methods . 8 Recent Advances in Numerical Modeling of Pipe Displacement . 9 2. EXPLORATORY WORK . 12 Geofoam Properties Used in Numerical Modeling . 12 Modeling Approach . 14 Transverse Model. 16 Longitudinal Model . 20 Recommendations from Preliminary Evaluations . 28 3. EPS GEOFOAM TESTING . 30 Test Equipment . 30 Test Procedures . 32 Monotonic Uniaxial Tests on Cylindrical Samples . 35 Test Specimens . 35 Results . 39 Monotonic Block Tests . 44 Test Specimens . 44 Results . 44 Test Results . 49 vi Discussion of Test Results . 59 Unloading Modulus . 59 Reloading Modulus . 60 Strain Rate Effects . 61 Stiffening of EPS due to Creep Strain . 63 Poisson’s Ratio. 63 Comparison to Published EPS Geofoam Testing . 65 Mathematical Model of EPS Behavior at Large Strains . 67 Conclusions . 75 4. GEOFOAM – PIPE INTERACTION TEST . 77 Objectives . 77 Description of Test Setup. 78 Pipe Load Test . 80 Test Results and Observations . 81 Vertical Load and Displacement . 82 Final Vertical Strain Distribution. 85 Numerical Modeling of Pipe Interaction Test . 86 Modeling Results . 96 Conclusions . 97 5. LATERAL SOIL-GEOFOAM-PIPE TESTS . 99 Experimental Setup . 99 Test Box Setup . 100 Materials . 103 EPS Geofoam . 103 Sand Backfill . 104 Procedures . 104 Testing Program . 110 Lateral Movement Experimental Results . 112 Test 1 – Single 610 mm Block Placed Adjacent to Pipe . 112 Test 2 – Sand Backfill Only . 114 Test 3 – Two 610 mm Blocks Placed Adjacent to Pipe . 116 Test 4 – Light-weight Cover with No Compressible Inclusion . 119 Comparison of Test Results . 122 Discussion of Experimental Results . 128 6. NUMERICAL MODELING OF LATERAL TESTS . 132 Numerical Modeling Program . 133 Benchmark Lateral Pipe Movement Modeling . 135 Lateral Pipe Test FLAC Modeling . 140 Conclusions . 145
All Factories Are Not the Same

Productivity the strategic variable is operational productivity. Its improvement has been the goal of numerous programs, a goal not often achieved. Superficial analysis of current manufacturing activities has contributed heavily to this lack of success. Considerable insight is required to pierce the haze surrounding manufacturing. Many analysts, lacking this insight, have relied on generalizations. However, a brief review of manufacturing systems, processes, technology, facilities, and personnel reveals that each factory is unique. Only when productivity programs reflect this factory-floor reality can they assume strategic importance.