Miracle-dz/UniFAR-FTUs huggingface dataset:
Regulatory Design for New Technologies: Spaghetti Junction or Bauhaus Principles for Regulating Innovative Cosmetic Products

Employing cosmetics as a case-study, this article reviews the readiness of the Australian, European Union (EU) and United States (US) regulatory structures to deal with new technologies such as those based on nano-science. Recent developments in the EU regulatory readiness would seem to suggest a development towards inserting nano-anchors in existing regulations, even if no immediate plans have been made to also include tailor-made provisions for those applications. This type of neat and functional design (hence the Bauhaus reference in the title) contrasts with the spaghetti junction approach that typifies other jurisdictions (and, until recently, the EU). The development and commercialisation of nanotechnologies has become an important adjunct for traditional industries due to the increasing consumer demand for improved products. These improvements may be aesthetic or functional in nature, or both, depending on the product itself. Unsurprisingly, consumer demand for cosmetic products that ‘renew, restore, and rejuvenate’ 1 has resulted in an escalating interest by the cosmetic industry in the use of nanotechnologies within cosmetic formulations. A number of cosmetic products which claim to incorporate engineered nanomaterials have already entered the market and include, for instance, anti-ageing creams, make up, hair care products, cleansers and moisturisers. It is thought that these products contain an assortment of engineered nanomaterials ranging from metal oxides, fullerenes, quantum dots, liposomes and nanospheres. Yet despite the reported wide-spread use of nanomaterials within the cosmetic industry 2 , the exact nature and extent to which engineered nanomaterials are being used by the cosmetics industry in their products remains ambiguous 3 . While the use of engineered nanomaterials within cosmetics offers a range of benefits, including increased transparency and solubility, there has been increasing debate over the potential health risks posed by some of the engineered nanoparticles
Two new proofs of the fact that triangle groups are distinguished by their finite quotients

In a 2016 paper by Alan Reid, Martin Bridson and the author, it was shown using the theory of profinite groups that if $\Gamma$ is a finitely-generated Fuchsian group and $\Sigma$ is a lattice in a connected Lie group, such that $\Gamma$ and $\Sigma$ have exactly the same finite quotients, then $\Gamma$ is isomorphic to $\Sigma$. As a consequence, two triangle groups $\Delta(r,s,t)$ and $\Delta(u,v,w)$ have the same finite quotients if and only if $(u,v,w)$ is a permutation of $(r,s,t)$. A direct proof of this property of triangle groups was given in the final section of that paper, with the purpose of exhibiting explicit finite quotients that can distinguish one triangle group from another. Unfortunately, part of the latter direct proof was flawed. In this paper two new direct proofs are given, one being a corrected version using the same approach as before (involving direct products of small quotients), and the other being a shorter one that uses the same preliminary observations as in the earlier version but then takes a different direction (involving further use of the `Macbeath trick').
Zellulare Transportfahrzeuge für flexible und wandelbare Intralogistiksysteme

Logistics Journal, Vol. 2012, Iss. 01 - Aufgrund stetig wechselnder Leistungsanforderungen volatiler Markte ist die Flexibilisierung des innerbetrieblichen Materialflusses eine Notwendigkeit. Klassische Fordermittel, wie zentral gesteuerte Stetigfordertechniksysteme, stosen dabei an ihre Grenzen. Auch die planerische Auslegung von starren Materialflusssystemen ist damit vor eine nicht losbare Aufgabe gestellt. Zellulare Intralogistiksysteme sind die heutigen Antworten auf diese Anforderungen. Die Zellularen Transportfahrzeuge „Multishuttle Move“ sollen Stetigfordersysteme und manuelle Transporte dort ablosen, wo ein hohes Mas an Flexibilitat und Wandelbarkeit gefragt ist, die Planungssicherheit nicht gewahrleistet ist oder aufgrund mangelnder Flexibilitat nicht automatisiert werden kann. In diesem Beitrag werden diese Systeme vorgestellt und deren Eigenschaften aufgezeigt.
Dynamic Modeling of Tie-bolt Rotors via Fractal Contact Theory and Virtual Material Method

Tie-bolt rotors, comprised of multiple stages of discs fastened by tie bolts, are commonly used in heavy-duty gas turbines. The contact interfaces between adjacent discs have considerable influence on the dynamic characteristics of tie-bolt rotors. Although many studies on the modeling of tie-bolt rotors have been reported, it is still a challenge to develop a relatively simple, efficient, and accurate model for such a kind of complex rotors. In this article, a new virtual material modeling method is proposed to analyze the dynamic characteristics of tie-bolt rotors. The elastic modulus and Poisson ratio of the virtual material are determined from the interface contact stiffness, which is derived based on the three-dimensional fractal contact theory. To verify the modeling approach proposed here, modal tests are conducted on a tie-bolt rotor specimen, of which the measured natural frequencies are compared with the simulation results. Finally, by using the verified modeling approach, the dynamic behaviors of tie-bolt rotors are investigated comprehensively, where the effects of fractal dimension parameters and preload level on rotor dynamics are evaluated.
Lay participatory design: A way to develop information technology and activity together

In this thesis a new phenomenon called lay participatory design (PD) is described and defined. The work is based on a long-term historical and ethnographic field study in a non-profit community of dog breeders. The case community is committed to the understanding and support of indigenous dogs and their hunting skills through the improvement of breeding knowledge using information technology. This is conceptualized as a user-field-design perspective within a natural cultural historical IT context. The new design mode based on this perspective can be seen as infrastructuring, which integrates the activity, community, and IT. Once in actual use, new knowledge and IT is put into practice in the field, which is the actual focus of the change. As it is practice field-driven, lay PD differs conceptually and theoretically both from conventional and professional IT expertise and IS design models, and from representative-, designor projectdriven approaches to PD and to design ethnography. Because of the traditional division of labour in IS these approaches often take only the professionalized (IT) design as the starting point and ignore the epistemological interests of ordinary people, non-IT-professional users active in their own, everyday domains and in their own participative and collaborative practices in the field of practice. The use-field-design perspective, which is conceptualized in lay PD, is complementing these approaches because it takes seriously ordinary people/users as local designers who are competent with topics, everyday domains, activity and IT located in the related field of practice. The case shows that IT and the core activity of a community can be developed together, and that this co-development is sensible. The results of this study suggest that lay PD concepts can describe essential features of the design process for everyday communities of practice. As a bottom-up form of systems design using everyday knowledge, lay PD can be adopted in other domains and study areas. Thus, lay PD is one new member in the emerging family of Participatory Design, Social Shaping of Technologies, and End User Development-driven systems.
Toxicity of food supplements as an adjuvant for COVID-19 treatment or prevention

Commercially available food supplements, especially vitamins and minerals, are be-coming increasingly popular in the era of COVID-19 pandemic. Sales of food supplements increased dynamically because of the belief that they could be more effective than conventional antiviral or corticosteroid drugs as well as missing the specific medical therapy for preventing or treating this disease. The greatest interest is associated with immune-related nutrients and antioxidant agents, including vitamin C, vitamin D, vitamin E, selenium (Se), and zinc (Zn). These are currently under clinical investigation for possible application in the prevention and management of COVID-19. This review summarizes postulated mechanisms of commonly used supplements suggested reducing the duration and severity of viral infections by improving immune response. Their toxicity in the context of potential adverse effects is also discussed. Whether these molecules and the amount could hurt patients with COVID-19 are research questions worth evaluating. Considering both efficacy and safety, evidence supporting larger intakes of specific nutrients with immune-boosting and/or antioxidant properties needs further research. Until relevant responses are provided, age and gender related tolerable upper intake levels for vitamins and minerals should be considered to avoid weight gaining as an additional risk factor of developing complications during the disease course, besides the risk of inappropriate doses associated with toxicity. Herein, high-quality information respecting specific nutrients proposed to have positive effect against COVID-19 is disseminated and certain research gaps are addressed, requiring the research on the health effects of supplements to be tightly correlated to age, nutritional status, wellbeing and particular to existing co-morbidities.
Importance Performance Analysis (IPA) on Tourism Destination Competitiveness in Mabul Island, Sabah

Mabul Island is a popular diving site for divers, with its main appeal of marine life as one of the most visited islands in Malaysia. If the island is not protected from tourist activities, its image as a tourist destination may deteriorate. This research focuses on measuring the tourism destination competitiveness by evaluating the sustainable features of Mabul Island using Importance Performance Analysis (IPA). The aim is to identify the most essential features of Mabul and evaluate its performance. The survey questionnaires were distributed to tourists who visited Mabul Island between 2017 and February 2020. Six (6) attributes that represent tourism destination competitiveness (TDC); destination management, natural resources, quality service and safety, location and accessibility, E-business, and sustainable tourism were tested. Data were analysed using mean and standard deviation and later, paired t-tests were employed to examine the statistical differences between the means of importance and performance. Only two variables; locality and accessibility, and E-business indicated a statistical significance between importance and performance rated by respondents. The mean values were also plotted into the IPA matrix to visually present the results based on four (4) quadrants: Sustainable tourism is the only attribute in the ‘keep up the good wor k’ quadrant; Destination management, natural resources, and quality service and safety are in the ‘low priority’ quadrant; Location locality and accessibility is in ‘concentrate here’ quadrant; E - business is plotted in ‘possible overkill’ quadrant. These findings are the valuable information for Sabah Tourism and relevant authorities to enhance Mabul Island and ensure its competitiveness as a desired tourism destination in Malaysia. This study suggested tourism policymakers and destination managers to do necessary monitoring and assessment on a regular basis to preserve the island for tourism purposes.
Portal Body-scaled ratio as a control parameter for prehension in 5-to-9-year-old-children

The purpose of the experiment was threefold: (a) To find evidence that grasping is body-scaled and thus remains invariant during development; (b) to seek evidence that the body-scaled ratio of cube and hand size serves as a control parameter for the phase transition from one-handed to two-handed grasping by identifying the presence of sudden jump, enhanced variance, multistability, and hysteresis; and (c) to examine whether the stability properties of the observed grasping patterns increase with age. Thirty-three children aged 5, 7, and 9 years old were required to grasp and lift 14 cardboard cubes of different sizes (2.2, 3.2, 4.2, etc. to 16.2 cm diameter). Three conditions were used: (a) an increasing condition with sizes ordered from the smallest size to the largest; (b) a decreasing condition, with the sizes ordered from the largest to the smallest; and (c) twice in a different random order. Video recordings were analyzed and scored for the percentage of one-handed grasps. The results showed that the shift from one-handed to two-handed grasping occurred at the same body-scale ratio between cube size and finger span for all three age groups. Evidence was found for the presence of a sudden jump, enhanced variance, multistability, and hysteresis, indicating that the body-scaled ratio of cube and hand size serves as a control parameter. No change with age for the stability properties of the grasping patterns were observed. q 1998 John Wiley & Sons, Inc. Dev Psychobiol 33: 351–361, 1998
Tapping global human resources in an MBA teaching team : insights with implications for management education worldwide

It is found that geographic diversity, respect for differing beliefs, encouraging feedback, active participation and interaction with the students, and techniques such as active listening, contribute an architecture and atmosphere to student learning, teacher effectiveness and program excellence in virtual education. One functioning teaching team in University of Maryland University College’s online MBA program provides the action research foundation underpinning the findings. A widely dispersed team of academics and assistants have documented the ways they enhance educational information for students in the program. Assessment activities, supplementary communications and biographical information contribute to student perception of the quality of management education in the program. Mechanisms for effectively tapping a global faculty team are discussed and are informative for administrators and academics alike.
Mitochondrial GTP Regulates Glucose-Induced Insulin Secretion

Nucleotide-specific isoforms of the tricarboxylic acid (TCA) cycle enzyme succinyl-CoA synthetase (SCS) catalyze substrate-level synthesis of mitochondrial GTP (mtGTP) and ATP (mtATP). While mtATP yield from glucose metabolism is coupled with oxidative phosphorylation and can vary, each molecule of glucose metabolized within pancreatic beta cells produces approximately one mtGTP, making mtGTP a potentially important fuel signal. In INS-1 832/13 cells and cultured rat islets, siRNA suppression of the GTP-producing pathway (DeltaSCS-GTP) reduced glucose-stimulated insulin secretion (GSIS) by 50%, while suppression of the ATP-producing isoform (DeltaSCS-ATP) increased GSIS 2-fold. Insulin secretion correlated with increases in cytosolic calcium, but not with changes in NAD(P)H or the ATP/ADP ratio. These data suggest a role for mtGTP in controlling pancreatic GSIS through modulation of mitochondrial metabolism, possibly involving mitochondrial calcium. Furthermore, in light of its tight coupling to TCA oxidation rates, mtGTP production may serve as an important molecular signal of TCA-cycle activity. KIBBEY, Richard G, et al. Mitochondrial GTP regulates glucose-stimulated insulin secretion. Cell Metabolism, 2007, vol. 5, no. 4, p. 253-64 DOI : 10.1016/j.cmet. 2007.02. 008
PENGARUH PELATIHAN TEAM BUILDING UNTUK MENINGKATKAN KOHESIVITAS TIM KERJA DI INNA GARUDA YOGYAKARTA

Intisari Pelatihan team building adalah salah satu intervensi pelatihan untuk meningkatkan kohesivitas tim kerja yang ditandai timbulnya sikap saling percaya, mampu menemukan solusi masalah-masalah yang dihadapi dan komunikasi intensif mengenai peranan masing-masing anggota tim guna melaksanakan suatu pekerjaan yang berhubungan dengan tugas dan tantangan bekerjasama untuk membangun sebuah tim kerja dalam bentuk permainan eksperimental secara indoor maupun outdoor. Penelitian menggunakan metode kuasi eksperimen dan teknik pengumpulan datanya dengan skala kohesivitas tim kerja yang kemudian dianalis dengan program SPSS for windows 13.0 dengan menggunakan uji-t untuk mengetahui efektivitas dari pelatihan. Pengumpulan data juga dengan dokumentasi, wawancara yang mendalam dan observasi untuk mengumpulkan data dari empat belas orang subjek penelitian yang kemudian dianalisis menggunakan metode kualitatif. Hasil penelitian ini menunjukkan sumbangan efektif pelatihan team building dalam meningkatkan kohesivitas tim kerja marketing aspek task sebesar 16,5 % dan aspek social sebesar 56,2%; sedangkan sumbangan efektif pelatihan team building dalam meningkatkan kohesivitas tim kerja HRD aspek task sebesar 16,5% dan aspek social sebesar 17,1%. Pelatihan team building mampu meningkatkan kohesivitas tim kerja karyawan di Inna Garuda Yogyakarta departemen marketing dan HRD yang dilihat dari hasil analisis kelompok rata-rata skor kohesivitas pada tim marketing aspek task maupun aspek social diketahui bahwa terdapat perbedaan yang signifikan (p<0,05), pada aspek task amatan pretest-posttest p=0.038, amatan posttest-follow up p=0.023, amatan gain 1-gain 2 p=0.025 dan aspek social amatan pretest-posttest p=0.011, amatan posttest-followup p=0.015, amatan gain 1-gain 2 p=0.018; begitu pula pada pada tim HRD aspek task maupun social diketahui bahwa terdapat perbedaan yang signifikan (p<0,05), pada aspek task amatan pretest-posttest p=0.025, amatan posttest-follow up p=0.023, amatan gain 1-gain 2 p=0.024; aspek social amatan pretest-posttest p=0.017, amatan posttest-follow up p=0.018, amatan gain 1-gain 2 p=0.011. Dari hasil analisis tersebut diperoleh kesimpulan bahwa ada pengaruh pelatihan team building dengan kohesivitas tim kerja baik pada aspek tugas (task) dan sosial (social) pada tim marketing dan manpower (HRD) dimana tim marketing dan manpower (HRD) termasuk sebagai kelompok boundary role person (BRP). Kata Kunci : pelatihan team building, kohesivitas tim kerja
Learning from instances represented as spatially overlapping point sets

This paper promotes the view that in numerous machine learning problems and domains it is valuable to represent instances as point sets and to use the spatial overlap between these point sets as a measure of distance between instances. Our speciﬁc contributions are as follows. First, we present a new measure of spatial overlap, and we show that the measure is well-motivated and computationally tractable. Second, we use this measure of spatial overlap to solve three concrete machine learning problems, in clustering, text processing, and protein structure analysis. Finally, we contrast our approach with a variety of other meth-ods that consider the spatial arrangement of point sets.
SPACE VECTOR PULSE WIDTH MODULATION OF A MULTI-LEVEL DIODE CLAMPED CONVERTER WITH EXPERIMENTAL VERIFICATION

This paper presents the analysis of a multi-level diode clamped converter (DCC) which is implemented using space-vector pulse width modulation (SVPWM) technique, widely considered as the most efficient and easily applied modulation technique in most industrial drives and control applications. It also focuses on the step by step development of MATLAB /SIMULINK modeling of the space vector pulse-width modulation and the spectral analysis of the resultant waveforms obtained from the modulation results were carried out. Results of the simulations obtained from DCC using SVPWM were equally presented and analyzed. This paper used generic on-time application method to realize the application time for the zero vector and two adjacent active vectors in determining the switching process of the multilevel DCC, quite unlike the look-up table which is common in this area. To verify the analysis, a small scale experimental work, was carried out. All experimental works were done in the laboratory and the results confirm the simulation results obtained from the SIMPLORER Student version 6 Software used in simulating the un-modulated three-level diode clamped converter.
Survey of Eye Tracking Methods and Gaze Techniques

: In Investigation of eye-development is being utilized in Human Computer Interaction (HCI) inquire about. Eye - look following is one among the premier testing issues inside the territory of Computer vision. The aim of this paper is to sitting a review of latest research during this continued development of eye gaze tracking. This overview includes the fundamental definitions and terminologies, recent advances within the field and at last the requirement of future development within the field.
Investigating common SCADA security vulnerabilities using penetration testing

Supervisory Control and Data Acquisition (SCADA) systems were developed to assist in the management, control and monitor of critical infrastructure functions such as gas, water, waste, railway, electricity and traffic. In the past, these systems had little connectivity to the Internet because they ran on dedicated networks with proprietary control protocols and used hardware and software specific to the vendor. As a result, SCADA systems were secure, and did not face challenging vulnerabilities associated with the Internet. The need for remote connectedness, in order to collect and analyse data from remote locations, resulted in SCADA systems being increasingly getting connected to the Internet and corporate networks. Therefore, SCADA systems are no longer immune to cyber-attacks. There are reported cases on cyber-attacks targeted at SCADA systems. This research utilises penetration testing to investigate common SCADA security vulnerabilities. The investigation is conducted through experiments, under two different scenarios. Experiments were conducted using virtual plant environment. The results revealed vulnerabilities which are considered as common by the Idaho National Laboratory and others which are not common. Recommendations are provided on how to mitigate the vulnerabilities discovered in this research.
Co-creation: Interface for Online Affective Experience and Repurchase Intention

The study proposes a comprehensive model framework applying co-creation and satisfaction in a moderated mediated mechanism for improving customer Online Repurchase Intention (ORI) via Affective Experiential State (AES). A cross-sectional survey collected data from 542 Indian respondents who do online shopping. Using structural equation modeling the results reveal that mediation effects of Online Shopping Satisfaction (OSS) vary between high and low-level of customer co-creation. Results further reveal that AES is a very influential factor in affecting customers ORI and OSS mediates the effects of AES on customer repurchase intention.
Fatal cerebral hemorrhage revealing acute lymphoblastic leukemia with leukostasis

1. Service of Anesthesiology and Intensive Care Unit, Third Military Hospital, Laayoune, Morocco 2. Service of Anesthesiology and Intensive Care Unit, Third Military Hospital, Laayoune, Morocco 3. Service of Anesthesiology and Intensive Care Unit, Military Teaching Mohammed V Hospital, Rabat, Morocco 4. Medico-Surgical Pole of laayoune, Sakia El Hamra Region, Service of Gastro-Enterology and Proctology, Third Military Hospital, Laayoune, Morocco 5. Service of Anesthesiology and Intensive Care Unit of Severe Burn Management, Military Teaching Mohammed V Hospital, Faculty of Medicine and Pharmacy of Rabat, Morocco