Miracle-dz/UniFAR-FTUs huggingface dataset:
Menilai Kualitas Hidup Anak Penyandang Hemofilia

Hemofilia merupakan penyakit congenital defisiensi faktor koagulasi dengan manifestasi perdarahan. Hemofilia dapat mengganggu kualitas hidup fisik, sosial, sekolah dan emosi penyandangnya. Salah satu instrumen untuk menilai kualitas hidup anak adalah pediatric quality of life questionnaire/PedsQL; penggunaannya di kalangan penyandang hemofilia anak dapat menunjang tatalaksana.Hemophilia is a congenital coagulation deficiency associated with bleeding manifestation. Hemophilia can affect physical, social, school and emotional quality of life; children with hemophilia can have lower self perception compared to healthy children. Pediatric quality of questionnaire/PedsQL is an instrument for assessment of quality of life in children; it use among children with hemophilia can improve their management.
Hot Water Treatment as Seed Disinfection Techniques for Organic and Eco-Friendly Environmental Agricultural Crop Cultivation

Seed is an essential input to sustain agricultural productivity. The expansion of agricultural areas to meet global food demand contributes to the emergence of pathogenic microorganisms that contaminate and infect crop seeds. Conventional technologies in controlling seed-borne diseases are, however, not environmentally sustainable. This inspired the authors to explore existing literature on organic disinfection techniques for crop production. Various integrated seed disinfection techniques for major food crops, including rice, wheat, barley, millet, buckwheat, and sorghum, have been presented in this study. Moreover, the authors explored the potentials of hot water treatment as an alternative treatment method in meeting the ideal seed quality for cultivation.
A sub-micron-thick InGaAs broadband (400-1700 nm) photodetectors with a high external quantum efficiency (>70%)

A sub-micron-thick InGaAs photodetectors (PDs) with a broad spectrum coverage (400-1700 nm) and high external quantum efficiency (EQE) (>70%) were successfully demonstrated through guided-mode resonance structure and surface layer thinning process. It showed the outstanding EQE of 83.8%, and 65.5% at 1000 nm, 1550 nm for 500-nm-thick InGaAs absorption layer, respectively. Compared to previous results, thickness reduction by 6.8 times and comparable QE were simultaneously achieved.
Rising Stars

We use the UK's 2014 Research Excellence Framework (REF) to study which attributes characterize a top-scoring (four-star) publication in Economics and Econometrics. We frame the analysis as a classification problem and, using information in official documents, derive conditions to infer the unobservable score that panellists awarded to each publication. Juxtaposing institutions' submissions with REF outcomes provides information on the unobservable pass-marks used for assigning quality levels, which respond to journal prestige measured by the Thomson Reuters Article Influence Score. We explore this statistical feature in the econometric analysis, which reveals the limited contribution to awarded quality made by other publication attributes, possibly unobservable to us, conditional on the Article Influence Score. We conclude that, in large-scale and costly evaluations such as the REF, the time-consuming task of peer reviews should be devoted to publications not in academic outlets with unambiguously top-scoring bibliometric indicators of journal impact. Our model also predicts a ranking of academic journals consistent with the classification of REF panellists.
role of vitamin D supplementation in lifelong premature ejaculation

Background: Premature ejaculation (PE) is defined as persistent or recurrent ejaculation with minimal sexual stimulation before, upon, or shortly after penetration and before the person wishes it. Aim and objectives: The aim of this study was to measure the serum level of 25-hydroxyvitamin D (25 (OH) D) in lifelong premature ejaculation patients and evaluate the role of 25-hydroxyvitamin D (25 (OH) D) supplementation in these patients with low or in sufficient level of 25-hydroxyvitamin D (25 (OH) D). Subjects and methods: A total of 80 consecutive men who presented with lifelong PE. Results: The mean PEDT showed a statistically significant decrease after treatment. The mean IELT in the included cases before treatment with vitamin D is 31.14 ± 20.511 and the mean IELT in the included cases after treatment is 48.86 ± 26.432. The mean IELT showed a statistically significant increase after treatment. Conclusion: This study demonstrates that lower vitamin D levels are associated with the acquired PE. The result of our study showed that the role of serum vitamin D levels should be investigated in the etiology of acquired PE. Perhaps supplementation of vitamin D in men with acquired PE will ameliorate the sexual health of these patients.
Mutually coupled circuits based on modified voltage differencing transconductance amplifier with tuneable characteristics

The paper presents a new mutually coupled circuit (MCC) based on a modified voltage differencing transconductance amplifier (MVDTA), designed using the modified Gorski‐Popiel technique. The proposed synthetic transformer (ST) circuit uses two MVDTAs as active elements, and all passive elements are grounded—two capacitors and two resistors. Thanks to the newly established coupling method‐connections, it is provided with independent electronic control of primary and secondary self‐inductance, as well as mutual inductance, via bias voltages of MVDTAs. In addition, it is very easy to provide the conditions by which symmetrical couplings are achieved. Monte Carlo analysis is carried out to verify the example application's robustness against the variation of the active and passive elements. In order to verify the results and conclusions reached through theoretical analysis, simulation testing was performed in the PSPICE software environment, both in the time and frequency domains. The functionality of the proposed MCC is shown in the example of a double‐bandwidth filter (double‐tuned band‐pass filter [DTBP]), while in order to accurately illustrate the superiority of the proposed solution, a comparison was made with similar circuits that are known from the professional literature. The proposal is also supported by experimental results (with off‐the‐shelf components IC MAX435) in order to confirm the workability of the proposed solution.
Long-term durability assessment of 3D printed concrete

Abstract Concrete 3D printing can be described as a revolution conquering the modern construction field. However, additive manufacturing is still confronted with many challenges and several limitations, such as the absence of building codes that regulate this construction approach. This technology is known to be environmentally friendly and its market is widening its horizons by implementing 3D printed concrete in harsh environments, such as bridges, infrastructures, and maritime applications. In this regard, the durability of those structures should be assessed to ensure sustainability. This study consists of assessing the durability of 3D printed concrete by comparing printed and casted samples aged by sulfuric acid attack. Three mixes were subjected to 0.5% sulfuric acid solution over 142 days. In addition to visual inspections of the samples, the mass loss was recorded periodically. Moreover, the total water porosity and the mechanical performance were evaluated. Both printed and casted samples showed degradation when placed in acid solutions, but the printed ones slightly resisted better during the first 84 days. However, after that date, both printed and casted samples presented comparable resistance. In addition, the mechanical performance came in accordance with the mass loss to prove that printed samples resisted well the acid attack by not losing much strength. In contrast, the strength drop rates in degraded printed samples were higher than those in the degraded casted elements between days 112 and 142. Moreover, the water porosity test showed that printed elements have a denser concrete matrix which protects the elements against chemical ingression.
Multi-Stage Machine Learning Enhanced DSP for DP-64QAM Coherent Optical Transmission Systems

We propose to improve DSP for coherent-signal recovery with distributed multi-stage machine-learning algorithms. Experiments demonstrate more-than-3-dB and 1-dB improvements in OSNR sensitivities for 40-GBd and 60-GBd DP-64QAM at BER thresholds of 4.5×10−3 and L6×10−2 respectively.
Rotor Temperature Estimation for Magnetically Suspended Turbo Molecular Pump Based on Flux Linkage Identification

Monitoring rotor temperature is a significant issue for safe operations in magnetically suspended turbo molecular pump (MSTMP). The increase in rotor temperature may cause the irreversible demagnetization of the permanent magnet (PM) and destroy the vacuum environment, eventually affecting the efficiency and security of the MSTMP system. Unfortunately, the direct measurement of the rotor temperature is complicated in practice due to the difficulty of accessing temperature sensors on a rotating shaft. This article proposes a novel rotor temperature estimation method based on the identification of the PM flux linkage. In order to address rank-deficiency in the identification of multiparameters, the resistance is calculated from the measured stator temperature, and two recursive least square (RLS) algorithm segments are combined to identify the inductance and flux linkage. Furthermore, the dynamic factor is introduced into the RLS algorithm to enhance the identification accuracy and convergence rate of the algorithm. The experiment results on the MSTMP test rig, equipped with the infrared temperature measuring module, demonstrate that the identified flux linkage has a good performance for the estimating rotor temperature under different working conditions.
THE POSTPANDEMIC REVITALIZATION OF A MINORITY SERVING INSTITUTION THROUGH STRUCTURAL AND OPERATIONAL ORGANIZATIONAL CHANGES

"St. Augustine College, a small, bilingual higher education institution, survived the pandemic by implementing structural and operational changes. The primary objective was two-fold: to create organizational changes that addressed the consequences of an unprecedented pandemic and to create the tools and mechanisms needed to sustain those organizational changes. Despite the circumstance, the institution’s commitment to its nontraditional student population, primarily female (78%) and Hispanic students (85%), motivated the necessary changes. The theoretical framework that supports this research study is the work of Kurt Lewin (1942)’s 3-Stage Model of Change. A mixed methods study determined the framework for data collection and analysis. The newly created Office of Academic Effectiveness (OAE) was the unit of analysis. The OAE is responsible for the quality assurance of the institution. Through qualitative data including interviews and observations, the Latino Educational Model, the new foundational teaching and learning philosophy of the institution, was developed. The quantitative data that served as the model’s creation was generated from four satisfaction surveys as well as students’ evaluations of course and instructors. This study provides a close examination of the office’s accomplishments and failures, institutional obstructions and passageways, and the balancing of existing traditions with new best practices. As a result of an arduous reframing process intended to revitalize the traditional culture, the college community united to create new units, revamp enrollment and admission procedures, update technology for different instructional delivery modalities, hire system disruptors, design and implement new policies, enforce assessment measures, craft onboarding regulations, establish faculty evaluation guidelines, build new academic programs, restructure and reevaluate the curricula, set up academic internships, conceive new certificates, and rebrand the institution, among other initiatives. The institutionalization of these changes seems to be the catalyst that will lead the institution to reclaim its position in the higher learning community. "
High-Speed Digital Control in a Switching-Synchronized Sampled-State Space for Variable Frequency Multi-Phase Buck Converters

This paper presents a new method for control-ling variable frequency, multi-phase buck converters. At the MHz-range switching frequency for each phase, cycle-by-cycle digital control of current and voltage results in a fast transient response to and fast settling from disturbances. A key challenge in adding phases or increasing frequency is maintaining the ability to measure voltage without interference from switching transients; cycle-by-cycle voltage averaging is fast and largely impervious to these effects. Additional benefits include ease of design and implementation. Theory and modeling are presented and results are demonstrated in simulation.
Digital Twin-Based Integrated Monitoring System: Korean Application Cases

A digital twin is a virtual model of a process, product, or service, which is one of the key technologies in the fourth industry. The pairing of the virtual and physical world allows analysis of data and monitoring of systems to head off problems before they occur. This paper presents a digital twin architecture and a system based on an interoperable data model. It explains how to build a digital twin for the integrated control monitoring using edge devices, data analytics, and realistic 3D visualization. The system allows continuous collaboration between field engineers for data gathering, designers for modeling 3D models, and layout engineers for layout changing by generating 3D digital twin models automatically. The system helps stakeholders focus on their respective roles to build digital twins. Examples applied to the Korean automotive parts makers are also introduced in this paper. The system can be easily used by small and medium-sized enterprises (SMEs) as well as large companies. Beyond simply watching the production site with CCTV, the production site can be intuitively managed based on the digital twin.
Improved Power Density of a 6 kV, 1 MW Power Electronics Building Block Through Insulation Coordination

In this work, key aspects of the insulation coordination in a 6 kV, 1 MW power electronics building block (PEBB) is presented. Each PEBB can be stacked in various series-parallel configurations as part of a modular multilevel converter sustaining at least 30 kV common mode. Ansys Maxwell 3D and COMSOL Multiphysics were used for electric field analysis to aid in the design of component and system level insulation. Design and analysis of a PCB-based bus with capacitor daughtercards and high voltage considerations for the cooling system are presented. Insulation integrity of key systems were verified to be partial discharge free at their maximum voltage rating.
Nutritional Interventions to Improve Cachexia Outcomes in Cancer—A Systematic Review

Background and Objectives: The prevalence of cachexia has increased across all of the cancer types and accounts for up to 20% of cancer-related deaths. This paper is a systematic review of nutritional interventions aiming to improve cachexia outcomes in cancer, focusing on weight gain. Materials and Methods: A search in Medline and Elsevier databases for articles up until the 23 January 2022, was conducted. Results: Out of 5732 screened records, 26 publications were included in the final analysis. Four randomized clinical trials showed a significant body weight (BW) increase in patients treated with eicosapentaenoic acid (EPA), β-hydroxy-beta-methyl butyrate (β-HMB), arginine, and glutamine or marine phospholipids (MPL). An upward BW trend was observed in patients treated with L-carnitine, an Ethanwell/Ethanzyme (EE) regimen enriched with ω-3 fatty acids, micronutrients, probiotics, fish oil, a leucine-rich supplement, or total parental nutrition (TPN) with a high dose of a branched-chain amino acid (BCAA). Conclusions: Although clinical trials relating to large numbers of nutritional supplements present promising data, many trials provided negative results. Further studies investigating the underlying mechanisms of action of these nutritional supplements in cancer cachexia are needed. Early screening for cancer cachexia risk and nutritional intervention in cancer patients before aggravating weight loss may stabilize their weight, preventing cachexia syndrome. According to the GRADE methodology, no positive recommendation for these nutritional supplements may be expressed.
Metformin Enhances the Anti-Cancer Efficacy of Sorafenib via Suppressing MAPK/ERK/Stat3 Axis in Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) incidence, as well as related mortality, has been steadily increasing in the USA and across the globe, partly due to the lack of effective therapeutic options for advanced HCC. Though sorafenib is considered standard-of-care for advanced HCC, it only improves median survival by a few months when compared to placebo. Sorafenib is also associated with several unpleasant side effects that often lead to early abatement of therapy. Here, we investigate whether a combination regimen including low-dose sorafenib and a non-toxic dose of anti-diabetic drug metformin can achieve effective inhibition of HCC. Indeed, combining metformin with low-dose sorafenib inhibited growth, proliferation, migration, and invasion potential of HCC cells. We observed a 5.3- and 1.9-fold increase in sub-G1 population in the combination treatment compared to sorafenib alone. We found that the combination of metformin enhanced the efficacy of sorafenib and inhibited the MAPK/ERK/Stat3 axis. Our in vivo studies corroborated the in vitro findings, and mice harboring HepG2-derived tumors showed effective tumor reduction upon treatment with low-dose sorafenib and metformin combination. This work sheds light on a therapeutic strategy aiming to augment sorafenib efficacy or dose-de-escalation that may prove beneficial in circumventing sorafenib resistance as well as minimizing related side effects.
DFIG Oscillation Modes Causing Strong Dynamic Interactions to Degrade the Damping of Power System Low-Frequency Electromechanical Oscillations

Abstract Open-loop modal coupling is the closeness of an open-loop oscillation mode of a grid-connected DFIG to an open-loop electromechanical oscillation mode of a power system on the complex plane. When the open-loop modal coupling occurs, the dynamic interactions between the DFIG and the power system become strong and may degrade the damping of the low-frequency electromechanical oscillations (LEPOs) of the power system. In this article, analysis is carried out to explain why the open-loop modal coupling may cause the damping degradation of the LEPOs. By deriving the simplified open-loop transfer function matrices of the DFIG, existence of open-loop DFIG oscillation modes to cause the open-loop modal coupling is analytically examined. Conclusions of analytical examination are: (1) If the rotor speed is used as the input signal to the active power control outer loop of the rotor side converter (RSC) or the generic type 3 model is adopted by the reactive power control outer loop of the RSC, the DFIG may have an open-loop oscillation mode to cause the open-loop modal coupling; (2) The PLL may also contribute to an open-loop oscillation mode of the DFIG. Study cases are presented to demonstrate and evaluate the analysis and conclusions.
What Can We Learn from Depth Camera Sensor Noise?

Although camera and sensor noise are often disregarded, assumed negligible or dealt with in the context of denoising, in this paper we show that significant information can actually be deduced from camera noise about the captured scene and the objects within it. Specifically, we deal with depth cameras and their noise patterns. We show that from sensor noise alone, the object’s depth and location in the scene can be deduced. Sensor noise can indicate the source camera type, and within a camera type the specific device used to acquire the images. Furthermore, we show that noise distribution on surfaces provides information about the light direction within the scene as well as allows to distinguish between real and masked faces. Finally, we show that the size of depth shadows (missing depth data) is a function of the object’s distance from the background, its distance from the camera and the object’s size. Hence, can be used to authenticate objects location in the scene. This paper provides tools and insights into what can be learned from depth camera sensor noise.
Risk of Telemedicine Infeasibility: An Evidential Reasoning Approach

The viability of a telemedicine system is the strength of its business continuity. Business continuity can only stand if the telemedicine system remains continuously feasible. This article studies telemedicine risk in terms of its feasibility on all its five components: economical, technical, social, operational, and legal/ethical. Any deficiencies in one or more of the feasibility components will affect the system business continuity risk and can lead to infeasibility and possible dissolution. The telemedicine computing environment is full of uncertainties and ambiguities and it just involves too much background knowledge that Bayesian theory cannot accommodate. Decision theory however offers a basic evidence-based multi-criteria decision mechanism that can tackle those decision problems treating both quantitative and qualitative criteria under various uncertainties including ignorance and randomness. We propose an evidential reasoning model to assess a telemedicine business continuity risk based on infeasibility. This business continuity risk is modelled using Dempster and Shafer Theory as the plausibility of infeasibility of the telemedicine system. A numerical example is provided to demonstrate the working of the proposed risk assessment model.
Proteomic Assessment of C57BL/6 Hippocampi after Non-Selective Pharmacological Inhibition of Nitric Oxide Synthase Activity: Implications of Seizure-like Neuronal Hyperexcitability Followed by Tauopathy

Nitric oxide (NO) is a small gaseous signaling molecule responsible for maintaining homeostasis in a myriad of tissues and molecular pathways in neurology and the cardiovasculature. In recent years, there has been increasing interest in the potential interaction between arterial stiffness (AS), an independent cardiovascular risk factor, and neurodegenerative syndromes given increasingly epidemiological study reports. For this reason, we previously investigated the mechanistic convergence between AS and neurodegeneration via the progressive non-selective inhibition of all nitric oxide synthase (NOS) isoforms with N(G)-nitro-L-arginine methyl ester (L-NAME) in C57BL/6 mice. Our previous results showed progressively increased AS in vivo and impaired visuospatial learning and memory in L-NAME-treated C57BL/6 mice. In the current study, we sought to further investigate the progressive molecular signatures in hippocampal tissue via LC–MS/MS proteomic analysis. Our data implicate mitochondrial dysfunction due to progressive L-NAME treatment. Two weeks of L-NAME treatment implicates altered G-protein-coupled-receptor signaling in the nerve synapse and associated presence of seizures and altered emotional behavior. Furthermore, molecular signatures implicate the cerebral presence of seizure-related hyperexcitability after short-term (8 weeks) treatment followed by ribosomal dysfunction and tauopathy after long-term (16 weeks) treatment.