Miracle-dz/UniFAR-FTUs huggingface dataset:
Fostering creative thinking in ageing may prevent cognitive decline: selected behavioural and neural data

Streszczenie. Kreatywne lub innowacyjne myślenie może być rozumiane jako proces umysłowy prowadzący do powstawania nowych i użytecznych idei. Jest kluczową umiejętnością kognitywną pozwalającą skutecznie reagować na zmieniające się wyzwania życiowe. zachowanie tej umiejętności jako elastycznej i dającej się adaptować jest możliwe. W niniejszym artykule przedstawiam wybrane badania nad myśleniem innowacyjnym, których przedmiotem analiz był rozwój kreatywności i zdolności kognitywnych poprzez trening. Doniesienia z psychologii uzupełniane są danymi neurobiologicznymi, dzięki czemu podłoże behawioralnych efektów treningów innowacyjnego myślenia można wyjaśnić mechanizmami neuronalnymi zachodzącymi w mózgu, czyli mechanizmami neuroplastycznymi. Spostrzeżenie, że zachowanie i rozwijanie kreatywnego myślenia jest możliwe w starszym wieku, motywuje do podejmowania wysiłku w kierunku poznania i wykorzystania związków między innowacyjnym myśleniem a umiejętnościami kognitywnymi potrzebnymi w codziennym życiu; co z kolei może zapobiec związanemu z wiekiem uwstecznianiu procesów kognitywnych. Obiecujące modele treningów wzmacniających kreatywne myślenie oraz leżące u nich podstaw mechanizmy neuronalne nie przestają się pojawiać i udoskonalać.
Investigation of Psychometric Properties of Likert Items with the Same Response Categories Using Polytomous Item Response Theory Models

The purpose of this study was to investigate withinand between-threshold parameter invariance for items of a fourteen-item Positive Affect Scale developed to assess positive moods (like happy, peaceful, etc.) of university students. To test whether the estimated threshold parameters were as expected (1 to 5, with increments of 1) across all the 14 items, Graded Response, Partial Credit, and Rating Scale Models were fit the response data collected from 326 students. A comparison of the model fit statistics, such as the negative 2log likelihood and chi-square values, revealed that the Graded Response Model had the best fit and that the thresholds estimates for all the items in the Positive Affective Scale were reasonably close to the expected 1 to 5 values with increments of 1. The study illustrates how polytomous response models can be used to test the psychometric quality of items with ordinal rating scales.
Design of N-Way Dual-Frequency Power Divider Based on Genetic Algorithm

An optimized design of microstrip N-way dual-frequency power divider by genetic algorithm was proposed,which was composed of N two-section transmission line transformers and N isolated resistors.Ideal transmission-line model of power divider was analyzed in even-odd mode,and optimal parameters were obtained by genetic algorithm.The elitist strategy and crossover mutation of changing probability were preserved to prevent premature convergence and avoid the complex formula for achieving optimization results rapidly and efficiently.Optimized parameters of the power divider was verified by RF simulation software ADS.Results showed that impedance matches all ports and isolation degree meets application requirements.
Detection of Multiresistance Tuberculosis in the Surrounding of Tuberculosis Patients with Multiresistant Bacillus in Kinshasa (DRC)

Context - Diagnosis and early treatment of MDR-TB in contact cases is a major challenge in hope to reduce the burden of morbidity and mortality due to this condition. Objectives - The objective was to assess the prevalence of drug-resistant TB and to compare the phenotypic and genotypic profile of the contact case with that of the index. Material and Methods - Prospective cohort study of 240 household contacts of 59 MDR-TB cases diagnosed and having a positive Ziehl at Elonga, St Alphonse and CUK CSDT was carried out from July 1, 2011 to August 28, 2013. Two sputum specimens were examined in each suspected tuberculosis contact for Ziehl-Neelsen's Koch bacillus and cultured for susceptibility testing on Lowensten-Jensen medium. The tuberculin test was performed on each contact and the spoligotyping of the index of contact cases was performed to determine whether the strains were epidemiologically linked. Results - Twenty-nine contacts out of 240 (12.1%) had symptoms suggestive of tuberculosis and 29 strains of Mycobacterium were isolated from 18 HIV-positive and 11 HIV-negative patients. The identification of these strains shows 26 Mycobacterium. tuberculosis and 6 Mycobacterium africanum. Of these contacts, 23 had a positive Ziehl and 6 had a negative IDR and Ziehl with positive HIV status. The antibiogram performed shows 16 resistant strains at least to one antituberculosis drug. MDR-TB (6.3%) and among them 4.2% preXDR (10) and 0.4% XDR-TB were detected. The phenotypic profile of 15 strains of the contacts corresponded to that of the index case and among the 8 typed strains, six were identical to the source case and 2 had a different profile. Conclusion - The survey determined the prevalence of TB and MDR-TB among the index case contacts. The high proportion reported in this survey is reminiscent of the WHO's alarm bell for early detection to halt the spread of the disease in the population.
Effects of 4-Methylcyclohexanemethanol on Stress Response Pathway Regulators, in Saccharomyces Cerevisiae

Effects Of 4-Methylcyclohexanemethanol On Stress Response Pathway Regulators, In Saccharomyces Cerevisiae Suk Lan Ser Hydrotropes are small molecules capable of inducing liquid-liquid phase separation by altering the solubility and conformation states of organic compounds that are increasingly becoming important in organizing chemical reactions and regulating complexes. They prevent protein aggregation causing these proteins to form condensates. Mediator, a highly conserved multi-subunit complex, plays an important role in transcription. Med15, a subunit found within the tail domain of the Mediator complex, works with stress-induced transcription factors and is regulated by many kinases, including CDKs and the AMP kinase, Snf1. Living cells respond by changing molecular and cellular pathways when they are exposed to stressful conditions. Damage to intracellular molecules depends on the duration of stress exposure and the severity of the stressor. By studying cellular stress response through the Mediator complex in Saccharomyces cerevisiae, the molecular effects of MCHM (4-methylcyclohexanemethanol), a synthetic hydrotrope, can be determined. The hydrotropic nature of MCHM and how it interacted with the polymorphic polyQ tracts of Med15 likely caused protein folding aggregation, which eventually led to protein condensates. The tolerance towards MCHM and other chemical stressors such as 4-nitroquinoline-1-oxide (4NQO), hydrogen peroxide (H2O2), and hygromycin (HYG) are dependent on the genetic variation of Med15’s polyQ tract and the presence of Snf1. Genetic variations of Med15 influence the formation of LLPS by affecting how the fuzzy domains, which include the polyQ tracts of the subunit, interact with hydrotropes. These findings combined to characterize how different alleles of Med15 deal with stress-inducing conditions by studying its interactions with a hydrotrope like MCHM.
Non-thyroidal Illness 24

The non-thyroidal illness syndrome (NTIS) is a term used to describe alterations in thyroid function tests observed in critically ill patients in the absence of intrinsic thyroid disease. Several studies have demonstrated that it has a high prevalence among hospitalized patients and it is significantly associated with the severity and the outcome of the disease. In the last decades there has been a shift in our view of the pathogenetic mechanisms underlying the syndrome. It has been increasingly recognized that alterations in the hypothalamus and the pituitary play a predominant role in the pathogenesis of NTIS, whereas the contribution of peripheral pathways, such as deiodinase activity, does not seem to be as significant as considered in the past. The majority of studies agree that treatment with thyroid hormone (TH) is not beneficial. However, TH may be reserved as an option for high-risk patients with very low TH levels and protracted disease, in whom some degree of hypothyroidism may be present.
BIGDATA AND PREDICTIVE ANALYTICS IN THE ELECTION CAMPAIGN

: This electronic document is a “live” template. The various components of your paper [title, text, heads, etc.] are already defined on the style sheet, as illustrated by the portions given in this document. Do not use special characters, symbols, or math in your title or abstract. The authors must follow the instructions given in the document for the papers to be published. You can use this document as both an instruction set and as a template into which you can type your own text.
Modification of Ca 2 + Channel Activity by Deletions at the Carboxyl Terminus of the Cardiac a 1 Subunit *

Voltage-sensitive Ca2+ channels are multisubunit complexes that include, among others, a large al subunit, which by itself is sufficient to form a channel. Several genes encoding L-, N-, and P-type Ca2+ channels have been cloned. These a1 genes share a high degree of sequence homology in the putative transmembrane regions, but vary substantially in the putative intracellular loops and the flanking amino and carboxyl termini. In the present study, we investigated the functional roles of the 665-amino acid long carboxyl terminus of a cardiac al by constructing deletion mutants. Expression in Xenopus oocytes of AC1866, AC1733, and AC1700, which lack from 307 to 472 amino acids at the carboxyl terminus, led to inward Ba2+ currents that were 4to &fold greater than observed with the 2171-amino acid long wild type al. Ionic currents increased without a change in the amount of charge moved during voltagedependent gating, suggesting that the increase in ionic currents was not due to an increase in the number of channels that were expressed. Single channel analysis revealed an unaltered unitary conductance. Thus, removal of up to 70% of the carboxyl terminus increased current density by facilitating the coupling between the voltage-dependent gating and channel opening, leading to an increased opening probability of the channel.
Effect of Tone Curve and Size on Kansei Evaluation of High Dynamic Range Images – Comparison of Japanese and Chinese Observers

: The effects of tone curve and display size on Kansei evaluation of High Dynamic Range (HDR) images were investigated with Japanese and Chinese observers. Forty HDR images (5 tone curves x 4 sizes x 2 contents) were evaluated for Kansei impression using a semantic differential (SD) method with 16 Japanese and 16 Chinese observers with normal color vision. For each adjective, the evaluation value was plotted against the average lightness of the tone curve, and the resulting curves were divided into ﬁve types: monotonic increase (MI), monotonic decrease (MD), peak in the upper portion (PU), peak in the lower portion (PL), and ﬂat (F). The results revealed size dependency in evaluations of “Easy to view” and “Difﬁcult to view”, which are PU and PL type adjectives, respectively. Size dependency was less prominent in the evaluations of adjectives categorized as MI, MD, and F types, suggesting that the inﬂuence of size is related to the effects of the tone curve. A factor analysis examining the evaluation data for both groups of observers extracted three factors for Japanese and two factors for Chinese observers. These results suggest that Kansei evaluation is more multilateral in Japanese observers than in Chinese observers.
A quantitative assessment on the design of a railway station

Public transfer stations are evolving into multi-functional public areas, attracting much more people. A lot of extra trips are made by public transport, causing the system to reach its capacity, especially during peak periods. Not only does the number of vehicles increase and does their occupancy degree grow, also congestion occurs in the transfer station itself. Unlimited expansions of the necessary transfer area is not an option: inner city areas must contain many different functions and public transport is just one of them. By adding more functions, the number of processes increases, their complexity increases and the design process also becomes more complex. Therefor, (simulation) models are needed to evaluate the location of the functions and the amount of infrastructure for each function. A key issue in this process is the comfort of the pedestrian: he must be able to walk to his destination inside the railway station, in a quick and comfortable way, along short paths without too many height differences. Also, the occurrence of congestion must be prevented as much as possible, in which especially stairs and escalators will form bottlenecks. In this paper an overview is given of the process of integration of the different functions, the timetables and the platform allocation to optimise pedestrian comfort. The applicability of this simulation model will be exemplified by a model of the station of Delft.
Masters Thesis: Suction Grasp Pose PlanningUsing Self-supervision andTransfer Learning

Planning grasp poses for a robot on unknown objects in cluttered environments is still an open problem. Recent research suggests that deep learning technique is a promising approach to plan grasp poses on unknown objects in cluttered environments. In this field, three types of data are used for training: (a) human labeled data; (b) synthetic data; (c) real robot data. Each of them has different properties in terms of the cost of collection and label accuracy. Recent approaches solely use a single type of data to train a model. The problem of such a methodology is that human labeled data is inaccurate and costly, synthetic data is scalable but inaccurate, and real robot data is accurate but costly. In this paper, we use the method of combining synthetic data and real robot data to train a Grasp Quality Convolution Neural Network (GQ-CNN). We collect a real robot dataset of 10000 datapoints without human-annotation, by running a UR5 equipped with a pneumatic suction gripper, with an algorithmic supervisor. We use this dataset to fine-tune a GQ-CNN model. We evaluate models both by classifying collected data and running physical robot grasping experiments. We use 50 unknown objects with prismatic and complex shapes for testing. Our method achieves 100% grasp success rate on these objects, and results suggest that the fine-tuned model learns the diameter and the great suction force of the suction cup.
Exploring Parents’ and Teacher’s Perception on the Effects of Kwartalino Financial Education on Kindergartens’ Financial Literacy

This study explored parents’ and teacher’s perception on the effects of a financial education program integrated and implemented in a kindergarten classroom. Parents’ and teacher’s perception regarding the effects of a financial education program on learners’ financial literacy is important as it provides vital feedback that could inform and improve other financial education programs targeted on this grade level. In this descriptive qualitative study, the researcher used interview to gather data. Data were analyzed following Lichtman’s (2013) Three C’s of Data Analysis. Results of the study revealed three themes: 1) emerging financial knowledge; 2) emerging financial skills; and 3) emerging financial attitude. Based on the result of the study, it can be concluded that the implemented financial education program had a positive effect on learners’ financial literacy. It helped learners understand financial concepts, develop money-management skills, and form positive financial attitudes. Thus, it is recommended that the program be utilized to a larger number of kindergarten classes and further study should be made to support the result of this study.
Molecular BioSystems

Individual cells within biological systems frequently coordinate their functions through signals initiated by speciﬁc extracellular protein interactions involving receptors that bridge the cellular membrane. Due to their biochemical nature, these membrane-embedded receptor proteins are diﬃcult to manipulate and their interactions are characterised by very weak binding strengths that cannot be detected using popular high throughput assays. This review will provide a general outline of the biochemical attributes of receptor proteins focussing in particular on the biophysical properties of their transient interactions. Methods that are able to detect these weak extracellular binding events and especially those that can be used for identifying novel interactions will be compared. Finally, I discuss the feasibility of constructing a complete and accurate extracellular protein interaction map
"Sex versus Gender: A biological location for gender, not sex.

Concerning effect size, a significant amount of research supports the 'similarities hypothesis' (Hyde, 2005, 2014), which states that differences in most, but not all, psychological variables are small (Joel, 2011; Hines, 2011). Of critical relevance to this current article is the phrase 'not all. ' Concerning animal studies, differences in human and animal brains have shown similar comparative morphology (Guillamon, Junque, & Gómez-Gil, 2016). Animal studies show neural and endocrine systems that likely account for the development and sensitivity of gendered parental behavior across the lifespan (Champagne & Curley, 2016; Lonstein et al., 2014). Indeed, gender is a concept relevant solely to humans, however. At the same time, this paper does not deny psycho-social influences on postnatal gender. It locates an uninfluenced prenatal gender as biological and located initially in a physiological place unrelated to later psycho-social influences. With this in mind, and due to ethical restrains in human studies, the reductionist study of animals can be legitimate in searching for understanding in the endocrinology and neurobiology of, for example, nurturant behaviors that are universal across many species and may underpin human behavior (Lonstein et al., 2014).
STUDY ON POWER BATTERY INTERNAL RESISTANCE MEASUREMENT METHODS

The resistances of two types of high-power Ni/MH battery which were 6.5Ah /1.2V(domestic),8.5Ah/12V(foreign)are measured for the purpose of comparing difference of results caused by various methods.Experimental results show that the results calculated by HPPC is higher than the data measured by mccf which is near the DCR result between 30%～70% soc.Using DCR and HPPC can simultaneously achieve discharge and regenerative resistance at wide range of soc.The mccf method can only measure discharge resistance between 30%～70% soc.The author propose combining the DCR and HPPC methods,medi/low rate series current and high rate current can be used to calculate dis/reg.resistance.
Reply to the Letter to the Editor Reply to Moons

(health-related) QOL is poor. Too often, the SF-36 is used as a health-related QOL instrument, whereas it says more about the perceived health status of the respondents. Second, the authors correctly explain in the methods section that the raw scores for each of the eight dimensions of the SF-36 have to be transformed into a score ranging from 0 to 100 [1]. However, in the results, they report SF-36 scores that are higher than 100. In the discussion section, they argued, ‘the authors did not transform the raw SF-36 values, allowing ageand gendermatched comparison [1]. ’ It is surprising that the authors use this comparison as an argument for not transforming the dimension scores. There is a plethora of articles in which the dimension scores were transformed, but still compared with matched data from normative groups. The fact that the scores were not transformed to a scale from 0 to 100 might be responsible for their findings being aberrant from the previous studies that have used the SF-36 in adults with congenital heart disease. Third, the SF-36 contains eight dimensions. These dimensions can be used to compute a physical component and mental component score. In the Loup study, also an overall QOL score was calculated. Computing such an overall SF-36 score is not advocated and seems inappropriate because constructs that are conceptually different are mixed. All these factors have potentially hampered the internal validity of the study. I join the authors in their statement that QOL research is needed to design, adapt and optimise the specific needs and complex follow-up of this special group of patients [1]. QOL studies require, however, a firm conceptual background and the use of rigorous research methods.
From Contr ol Effects to Typed Contin uation Passing

First-class contin uations are a powerful computational effect, allowing the programmer to expressany form of jumping. Types and e ect systems can be used to reason about contin uations, both in the source languageand in the target language of the contin uation-passing transform. In this paper, we establish the connection betweenan e ect system for rst-class contin uations and typed versions of contin uationpassing style. A region in the e ect system determines a local answer type for contin uations, such that the contin uation transforms of pure expressionsare parametrically polymorphic in their answer types. We use this polymorphism to derive transforms that make use of e ect information, in particular, a mixed linear/non-linear contin uation-passing transform, in which expressionswithout control e ects are passedtheir contin uations linearly . Categoriesand SubjectDescriptors D.3. 1 [Programming Languages ]: Formal De nitions and Theory; D.3. 3 [Programming Languages ]: LanguageConstructs and Features GeneralTerms Languages,Theory
Esfiha with added chayote peel flour: physical-chemical characterization and sensory analysis among children

The aim of the study was to evaluate the sensory acceptability of sfiha added to different levels of chayote peel flour (CPF). Also, determine the physical-chemical composition of greater than 2% of CPF reduced sensory acceptability (p<0.05) of the sfiha for all attributes and for the overall acceptance and purchase intention, in relation to the standard product. Formulation F2 was the one with the highest CPF content and with acceptance similar to the standard formulation. Higher levels of moisture, ash and dietary fiber and lower levels of carbohydrate and energy were observed for F2 compared to F1. There was no significant difference (p>0.05) for protein and lipid content between the two formulations. It is concluded that an addition level of up to 2% of CPF in sfiha is well accepted by schoolchildren. In addition, the CPF improves the nutritional value of the product, especially with the increase in dietary fiber and mineral matter.
Title: On the timing of bill length evolution in British great tits: A comment on Bosse et al. 2017. Running title: Evolution of bill length in great tits

: Bosse et al. (Science - 2017) investigated the genomic architecture and spatio-temporal variation in the bill length of the Great tit Parus major . They report a polygenic control of bill length and their analysis also suggests that UK birds have evolved longer bills than birds on mainland-Europe, potentially recently caused by the use of bird feeders. In contrast, using an alternative statistical approach, our analysis suggests a recent decrease in bill length in UK birds, even though they do have longer bills than great tits on mainland-Europe. This raises questions about the evolutionary mechanisms underlying increase on the long-term, but recent shrink, of bill length in UK great tits.