Miracle-dz/UniFAR-FTUs huggingface dataset:
Comparative analysis of fire loads in forest ecosystems disturbed by fire

RESUMEN En la actualidad existe poca informacion sobre las cargas de combustibles forestales en diferentes condiciones y ecosistemas. De acuerdo con esto, el objetivo del presente trabajo es compararla en bosques templados y selvas. Para lo cual se utilizo la metodologia de intersecciones planares. Una vez recabada la informacion en campo, se estimaron los combustibles en toneladas por hectarea de las diferentes categorias (tiempo de retardo). Se evaluaron 24 conglomerados en seis estados de la Republica Mexicana, de ellos, la mitad tenia la condicion de quemado. Los sitios que se ubicaron en bosque templado (Coahuila, Puebla y Jalisco) cuentan con una vegetacion dominante de pino-encino y una disponibilidad promedio de 17.90 ton ha -1 de biomasa. Mientras que en las areas con incidencia de fuego se observa una disminucion considerable de combustible, de casi 10 ton ha -1 . Para las areas que se situaron en selva (Baja California Sur, Quintana Roo y Yucatan) ocurrio lo contrario, ya que los sitios donde no hubo incendio disminuyo la carga de material combustible, en comparacion con los sitios quemados que mostraron un incremento superior al doble (9 ton ha
A comprehensive framework for advanced protein classification and function prediction using synergistic approaches: Integrating bispectral analysis, machine learning, and deep learning

Proteins are fundamental components of diverse cellular systems and play crucial roles in a variety of disease processes. Consequently, it is crucial to comprehend their structure, function, and intricate interconnections. Classifying proteins into families or groups with comparable structural and functional characteristics is a crucial aspect of this comprehension. This classification is crucial for evolutionary research, predicting protein function, and identifying potential therapeutic targets. Sequence alignment and structure-based alignment are frequently ineffective techniques for identifying protein families.This study addresses the need for a more efficient and accurate technique for feature extraction and protein classification. The research proposes a novel method that integrates bispectrum characteristics, deep learning techniques, and machine learning algorithms to overcome the limitations of conventional methods. The proposed method uses numbers to represent protein sequences, utilizes bispectrum analysis, uses different topologies for convolutional neural networks to pull out features, and chooses robust features to classify protein families. The goal is to outperform existing methods for identifying protein families, thereby enhancing classification metrics. The materials consist of numerous protein datasets, whereas the methods incorporate bispectrum characteristics and deep learning strategies. The results of this study demonstrate that the proposed method for identifying protein families is superior to conventional approaches. Significantly enhanced quality metrics demonstrated the efficacy of the combined bispectrum and deep learning approaches. These findings have the potential to advance the field of protein biology and facilitate pharmaceutical innovation. In conclusion, this study presents a novel method that employs bispectrum characteristics and deep learning techniques to improve the precision and efficiency of protein family identification. The demonstrated advancements in classification metrics demonstrate this method’s applicability to numerous scientific disciplines. This furthers our understanding of protein function and its implications for disease and treatment.
The impact of acute weight loss following bariatric surgery on Eustachian tube function

Obesity has emerged as a pressing concern in contemporary society, prompting an increase in bariatric surgery (BS) procedures for severe obesity management. Post-bariatric weight loss might cause complications, such as a reduction in the soft tissue surrounding the Eustachian tube, potentially affecting its function. This cohort prospective study, conducted between May and December 2022, aimed to assess the impact of post-bariatric acute weight loss on Eustachian tube function. A total of 54 cases of bariatric surgery and 157 control subjects were included in the study. Data on socio-demographics, weight, and the type of bariatric surgery were collected for the study group. ET function was assessed using the Eustachian Tube Dysfunction Questionnaire (ETDQ-7). Approximately 55% of the participants fell within the age range of 18-25 years, with the majority (91.4%) having not undergone bariatric surgery. Conversely, participants who underwent BS were significantly more prevalent in the older age groups, specifically those over 50, between 40-50, and 31-40 years (p<0.001). Our sample consisted of 82.5% females and 17.5% males, with BS being significantly more common among male subjects (45.9%) compared to females (21.3%) (p=0.002). The mean total ETDQ-7 in control subjects was significantly higher (11.29±5.49) compared to those who had BS (9.11±4.09). Moreover, when comparing the ETDQ-7 between subjects who had BS and the control group, no statistically significant differences were observed in the total ETDQ-7 score and across all seven items within the ETDQ-7. Based on these findings, bariatric surgery did not have a major effect on ET function.
Curvature-based interface restoration algorithm using phase-field equations

In this study, we propose a restoration algorithm for distorted objects using a curvature-driven flow. First, we capture the convex-hull shaped contour of the distorted object using the mean curvature flow. With the supplemented mass on the captured feature, we evolve the constraint mean curvature flow to a steady state, preserving the non-distorted region. With respect to the mass, we select a restorative shape by considering the square of the curvature derivative. The Allen–Cahn and Cahn–Hilliard equations are applied to the generated restored image from the implicit curvature motions represented by the order parameter. We impose the Dirichlet boundary condition for the order parameter and the Neumann boundary for the chemical potential to fix the feature and to inherit the mass conservation, respectively. We provided examples of the restoration of half-circle and parentheses-shaped objects to reconstruct a circle shape.
Maximum carotid intima-media thickness and NT-pro BNP in association with retinal vein occlusion

The purpose is to clarify the relationship between patients with retinal vein occlusion (RVO), maximal intima-media complex thickness (Max IMT), and N-terminal pro-brain natriuretic peptide (NT-proBNP), which is useful in assessing atherosclerosis. This was a retrospective observation, single center study. The patients were 86 RVO patients (male: female = 43:43, mean age 63.3 years), 25 with central retinal vein occlusion (CRVO) and 61 with branch retinal vein occlusion (BRVO), classified as ≧50 years old and <50 years old, Max IMT≧1.1 and less, NT-pro BNP≧55 and less. Results showed that Max IMT ≧1.1 was significantly more common in both the CRVO and BRVO groups at ≧50 years, and NT-pro BNP ≧55 was significantly more common in the CRVO group. Max IMT≧1.1 was seen in 80% of the BRVO group and in 85% of patients aged ≧50 years. Sixty-eight percent of patients in the CRVO group had Max IMT≧1.1, but none of those < 50 years had Max IMT≧1.1. Forty-eight percent of RVO patients had NT-pro BNP≧55, and significantly more patients had Max IMT≧1.1 than those who did not have NT-pro BNP more than 55 (p = 0.02). Multiple regression analysis with Max IMT as the dependent variable showed that age and NT-pro BNP were significantly associated with RVO (p = 0.015, 0.022). RVO patients were more likely to have a Max IMT≧1.1, which was associated with atherosclerosis. Max IMT and NT-pro BNP were also associated with RVO patients, so NT-pro BNP may be a marker of RVO.
Transcriptomic meta-analysis reveals ERRα-mediated oxidative phosphorylation is downregulated in Fuchs’ endothelial corneal dystrophy

Background Late-onset Fuchs’ endothelial corneal dystrophy (FECD) is a degenerative disease of cornea and the leading indication for corneal transplantation. Genetically, FECD patients can be categorized as with (RE+) or without (RE-) the CTG trinucleotide repeat expansion in the transcription factor 4 gene. The molecular mechanisms underlying FECD remain unclear, though there are plausible pathogenic models proposed for RE+ FECD. Method In this study, we performed a meta-analysis on RNA sequencing datasets of FECD corneal endothelium including 3 RE+ datasets and 2 RE- datasets, aiming to compare the transcriptomic profiles of RE+ and RE- FECD. Gene differential expression analysis, co-expression networks analysis, and pathway analysis were conducted. Results There was a striking similarity between RE+ and RE- transcriptomes. There were 1,184 genes significantly upregulated and 1,018 genes significantly downregulated in both RE+ and RE- cases. Pathway analysis identified multiple biological processes significantly enriched in both—mitochondrial functions, energy-related processes, ER-nucleus signaling pathway, demethylation, and RNA splicing were negatively enriched, whereas small GTPase mediated signaling, actin-filament processes, extracellular matrix organization, stem cell differentiation, and neutrophil mediated immunity were positively enriched. The translational initiation process was downregulated in the RE+ transcriptomes. Gene co-expression analysis identified modules with relatively distinct biological processes enriched including downregulation of mitochondrial respiratory chain complex assembly. The majority of oxidative phosphorylation (OXPHOS) subunit genes, as well as their upstream regulator gene estrogen-related receptor alpha (ESRRA), encoding ERRα, were downregulated in both RE+ and RE- cases, and the expression level of ESRRA was correlated with that of OXPHOS subunit genes. Conclusion Meta-analysis increased the power of detecting differentially expressed genes. Integrating differential expression analysis with co-expression analysis helped understand the underlying molecular mechanisms. FECD RE+ and RE- transcriptomic profiles are much alike with the hallmark of downregulation of genes in pathways related to ERRα-mediated OXPHOS.
Postsynaptic cell type and synaptic distance do not determine efficiency of monosynaptic rabies virus spread measured at synaptic resolution

Retrograde monosynaptic tracing using glycoprotein-deleted rabies virus is an important component of the toolkit for investigation of neural circuit structure and connectivity. It allows for the identification of first-order presynaptic connections to cell populations of interest across both the central and peripheral nervous system, helping to decipher the complex connectivity patterns of neural networks that give rise to brain function. Despite its utility, the factors that influence the probability of transsynaptic rabies spread are not well understood. While it is well established that expression levels of rabies glycoprotein used to trans-complement G-deleted rabies can result in large changes in numbers of inputs labeled per starter cell (convergence index [CI]), it is not known how typical values of CI relate to the proportions of synaptic contacts or input neurons labeled. And it is not known whether inputs to different cell types, or synaptic contacts that are more proximal or distal to the cell body, are labeled with different probabilities. Here, we use a new rabies virus construct that allows for the simultaneous labeling of pre- and postsynaptic specializations to quantify the proportion of synaptic contacts labeled in mouse primary visual cortex. We demonstrate that with typical conditions about 40% of first-order presynaptic excitatory synapses to cortical excitatory and inhibitory neurons are labeled. We show that using matched tracing conditions there are similar proportions of labeled contacts onto L4 excitatory pyramidal, somatostatin (Sst) inhibitory, and vasoactive intestinal peptide (Vip) starter cell types. Furthermore, we find no difference in the proportions of labeled excitatory contacts onto postsynaptic sites at different subcellular locations.
Penumbral thoughts: Contents of consciousness upon waking

Thoughts shape our experience, choice, and behaviour throughout the day. Yet the content of ‘penumbral thoughts’—first thoughts upon waking—has received very little research attention. Across seven independent samples (total N = 829), we used recall and reflection methods, solicited the same day, to understand what individuals think as they regain consciousness. These penumbral thoughts show remarkable thematic consistency: individuals were most likely to reflect on their somatic or psychological state, focus on temporal orientation, and prioritise waking actions. Survey results demonstrate that temporal and spatial orientation are dominated by the current time and the day ahead, rather than the past or other future timescales. Our results provide some insight into the order of priority in consciousness. We conclude that establishing one’s temporal position is important to the daily process of ‘rebooting’ conscious awareness.
Impact of fast‐track rehabilitation nursing on pressure ulcers and postoperative complications in patients with inter‐trochanteric fractures: A meta‐analysis

Abstract We sought to investigate the effects of fast‐track rehabilitation nursing on pressure ulcers, length of hospital stay and postoperative complications in patients with inter‐trochanteric fractures (ITF). The PubMed, Web of Science, Embase, Cochrane Library, China National Knowledge Infrastructure and WanFang databases were searched for randomised controlled trials (RCTs) published from inception to September 2023 on the application of fast‐track rehabilitative nursing to ITF. Two investigators independently screened the literature and performed data extraction and quality assessments using the Cochrane Risk of Bias Assessment Tool. The meta‐analysis was performed using RevMan 5.4. Overall, 22 RCTs involving 1904 patients were included. Meta‐analysis revealed that after fast‐track rehabilitation nursing intervention in patients with ITF, the occurrence of pressure ulcers (odds ratio [OR]: 0.29; 95% confidence interval [CI]: 0.18–0.47; p < 0.001) and postoperative complications (OR: 0.19; 95% CI: 0.14–0.26; p < 0.001) were significantly reduced and hospital stay was significantly shorter (standardised mean difference: –3.10; 95% CI: −3.82 to −2.38; p < 0.001). Nursing care for patients with ITF based on the concept of fast‐track rehabilitation is conducive to reducing the occurrence of pressure ulcers, lowering the occurrence of complications, shortening the length of hospitalisation and promoting postoperative rehabilitation.
Virus Zika en Centroamérica y sus complicaciones

El virus Zika (ZIKV) es un arbovirus, aislado por primera vez en Zika Uganda, reportandose el primer caso en humanos en 1954, desde entonces se han descrito casos en Africa, Asia, Oceania y en America. Centroamerica ha sido afectada, por cambios climaticos, pobreza y mal saneamiento ambiental. Su transmision es vectorial y puede tener transmision perinatal, transfusiones sanguineas o por semen infectado. Clinicamente se diferencian poco de Dengue y Chikungunya. Sus complicaciones son principalmente a nivel neurologico. Los Gobiernos de las regiones afectadas deberan tener politicas de control del vector, mejoria de viviendas y eliminacion de basuras.
Diabetes Care in the Hospital : Standards of Medical Care in Diabetes d 2018

The American Diabetes Association (ADA) “Standards of Medical Care in Diabetes” includes ADA’s current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to evaluate quality of care. Members of the ADA Professional Practice Committee, a multidisciplinary expert committee, are responsible for updating the Standards of Care annually, or more frequently as warranted. For a detailed description of ADA standards, statements, and reports, aswell as the evidence-grading system forADA’s clinical practice recommendations, please refer to the Standards of Care Introduction. Readers who wish to comment on the Standards of Care are invited to do so at professional.diabetes. org/SOC.
Clinical Management of Brugada Syndrome: Commentary From the Experts

Although there is consensus on the management of patients with Brugada Syndrome with high risk for sudden cardiac arrest, asymptomatic or intermediate-risk patients present clinical management challenges. This document explores the management opinions of experts throughout the world for patients with Brugada Syndrome who do not fit guideline recommendations. Four real-world clinical scenarios were presented with commentary from small expert groups for each case. All authors voted on case-specific questions to evaluate the level of consensus among the entire group in nuanced diagnostic and management decisions relevant to each case. Points of agreement, points of controversy, and gaps in knowledge are highlighted.
An Effective Video Collaboration of Pointer Indication by Curvature

Hand gesture recognition is a natural and intuitive way to interact with the computer, since interactions with the computer can be increased through multidimensional use of hand gestures as compare to other input methods. The purpose of this paper is to explore three different techniques for HGR (hand gesture recognition) using finger tips detection. A new approach called “Curvature of Perimeter” is presented with its application as a virtual mouse. The system presented, uses only a webcam and algorithms which are developed using computer vision, image and the video processing. KeywordsHuman computer interaction; hand gesture recognition; finger tips detection
Perfil clínico y abuso de metanfetamina no recreativa (shabú) entre los pacientes con ictus en la población filipina

Introducción. En la población filipina de Barcelona está aumentando el consumo crónico no recreativo de metanfetaminas (shabú). La población asiática presenta un patrón de ictus diferente, con mayor incidencia de hemorragias, y diferentes factores de riesgo vascular y conductas de salud. El objetivo es describir el perfil de ictus e incidencia de consumo de metanfetaminas en pacientes de origen filipino ingresados en nuestro centro. Pacientes y métodos. Se registraron datos demográficos, factores de riesgo vascular, datos clínicos y pronóstico. Se analizó la exposición a metanfetamina en muestras de plasma recogidas en el ingreso, que se analizaron por cromatografía líquida-espectrometría de masas. Resultados. Del total de 6.418 pacientes con ictus, se identificó a 73 pacientes filipinos (1,1%). La edad media era de 54,4 ± 12,1 años, el 54% eran hombres y el ictus era isquémico en el 64,4%. La hipertensión arterial fue el principal factor de riesgo. Diez (13,7%) pacientes dieron positivo a metanfetamina y anfetamina. Estos resultados confirman un consumo reciente de sustancias previo al ictus, principalmente en hombres (80%). En pacientes consumidores, un 60% presentaba un ictus hemorrágico, con mal pronóstico funcional a tres meses en el 55,6% de los pacientes. Conclusiones. En nuestro medio, los pacientes de etnia filipina ingresados por ictus en relación con consumo de shabú presentaron un perfil de edad más joven, con menor prevalencia de factores de riesgo vascular y predominio del subtipo hemorrágico. Se recomienda la determinación de metanfetamina en los pacientes filipinos con ictus debido a la alta prevalencia del consumo de metanfetamina en nuestro país.
Assessment of 2022 European LeukemiaNet risk classification system in real‐world cohort from China

The European LeukemiaNet (ELN) risk classification system for acute myeloid leukemia (AML) patients has been used worldwide. In 2022, the ELN risk classification system modified risk genes including CEBPA mutation status, myelodysplasia‐related (MR) gene mutations and internal tandem duplications of FLT3 (FLT3‐ITD).
Nowa odkrywka interglacjału na Winiarach koło Poznania

Neuer Aufschluss des Interglazials in Winiary bei Poznan Wahrend der Nivelation und der Regulationsarbeiten in der Gegend von Poznan sind in der Vorstadt Winiary interglaziale Gebilde zum Vorschein gebracht worden. Der Aufschluss in Gestalt einer Grube, in welcher man die Bohrung durchfuhrte, befindet sich in der Hohe von 80 m N. N. und in einer Entfernung von ungefahr 10 m von dem Seitenweg, welcher von 89,3 ab nach der Oborniki- Strasse fuhrt. Der zweite Aufschluss entstand durch Nivellierung des Hugels 82 u. d. M. N. In der Grube waren folgende Schichtverhaltnisse: 1. 1,20 m brauner Moranenlehm 2. 0,80 m Moranenlehm mit interglazialen Gebilden gemischt 5. 0,10 m dunkle tonige Gytia mit Muschelschalen 4. 0,30 m helle, kalkig-tonige Gytia mit Schneckenschalen 5. 1,50 m helle Quarzsande, unten schrag geschichtet und grob 6. Grand und Kies schrag geschichtet. Die in der Grube durchgefuhrte Bohrung gab in der Tiefe von 3 m unter Kies und Grand einen grauen Moranenlehm. Die Gytia lieferte reiches (40 Arten) palaontologisches Material, welches Herr J. Urbanski bearbeitet hat. Die pollenanalytischen Untersuchungen, von Frl. Dr J. Dyakowska durchgefuhrt, ergaben wenige Pollen Betula, Ainus und Graminae und Eupatorium canabinum F ruchte. Im zweiten Aufschlusse (siehe Profil u. Photographie) wurden uber den schrag geschichteten Kiesen und Grand zuerst schrag geschichtete Sande, darauf Quarzsande mit tonigen Einlagerungen und Gytia entdeckt. Uber diesen sehen wir horizontal liegende Quarzsande, welche von braunem Moranenlehm bedeckt sind. Die Gytia lieferte viele Pollen, welche Herr J. Bąkowski untersucht hat. Der Vergleich unserer Aufschlusse mit den interglazialen Schichten von Szeląg beweist, dass die interglazialen Bildungen von Winiary nur die hoheren Schichten des Interglazials von Szeląg darstellen; sie weisen auch andere klimatische Verhaltnisse auf. Die Gytien der Grube entsprechen einem kuhlen, die Gytien des Aufschlusses dagegen einem feucht-gemassigten Waldklima.
Emergence and collapse of reciprocity in semiautomatic driving coordination experiments with humans

Significance Simple and complex forms of machine intelligence are becoming involved in many collective action challenges humans face, including ensuring safety in groups on the move. However, the social repercussions of intelligent assistance are often overlooked. We used a unique cyber-physical lab experiment involving remote-control robotic cars and widely distributed online drivers. We show that autonomous safety systems in cars can degrade the ordinary norms of reciprocity between people. Humans have developed social norms, but these can collapse when people are allowed to leave their coordination decisions to machines.