Miracle-dz/UniFAR-FTUs huggingface dataset:
PENGARUH MANAJEMEN TALENTA TERHADAP RETENSI KARYAWAN MELALUI KETERIKATAN KARYAWAN SEBAGAI VARIABEL MEDIASI DI BPJS KESEHATAN KEDEPUTIAN WILAYAH SUMBAGTENG JAMBI

Perusahaan menghabiskan banyak sumber daya untuk mengadaptasi karyawan, terutama karyawan baru, dengan program kerja yang mereka miliki. Oleh karena itu, akan menjadi masalah jika karyawan yang terlatih keluar dari perusahaan. Masalah terkait retensi pegawai tidak hanya dapat terjadi di dalam perusahaan, tetapi juga dapat terjadi pada badan hukum publik seperti BPJS Kesehatan. Diketahui ada dua faktor yang dinilai berdampak pada retensi karyawan, yaitu manajemen talenta dan keterikatan karyawan. Berdasarkan informasi tersebut, penelitian ini bertujuan untuk mengetahui pengaruh talent management terhadap employee retention dengan employee engagement sebagai variabel mediasi. Penelitian ini merupakan penelitian asosiatif yang dilakukan di Kantor Deputi BPJS Kesehatan Wilayah Sumbagteng Jambi. Hasil penelitian ini menunjukkan bahwa variabel employee engagement berhasil memediasi hubungan antara variabel talent management dengan variabel employee retention. Namun berdasarkan hasil uji Sobel dan uji Baron-Kenny, pengaruh yang diterima oleh variabel employee retention akan lebih baik jika diberikan langsung oleh variabel talent management tanpa melalui perantara variabel employee engagement. Oleh karena itu, kebijakan talent management yang diterapkan oleh BPJS Kesehatan akan lebih baik jika fokusnya langsung pada upaya agar pegawai tidak keluar dari BPJS Kesehatan.
Liquid Biopsy in Cancer: Focus on Lymphoproliferative Disorders

Simple Summary Liquid biopsy (LBx) is a novel and promising approach in precision medicine, suitable for patient management in a wide range of medical conditions. Its utility in oncology ranges from disease screening to early diagnosis and treatment. LBx has several strengths, such as safeness, quickness of execution, and repeatability, compared to old-fashioned solid biopsy techniques; indeed, LBx requires the collection of a small number of biospecimens. LBx has been proven to be accurate and reliable, as demonstrated in several clinical studies, and it could have a surprising impact on survival and quality of life for cancer patients in the near future. With the present review article, we aim to summarize LBx characteristics, considering both the clinical and the laboratory settings; and to collect the most recent evidence within the oncology field, with a specific focus on blood cancers. Abstract Within the context of precision medicine, the scientific community is giving particular attention to early diagnosis and intervention, guided by non-invasive methodologies. Liquid biopsy (LBx) is a recent laboratory approach consisting of a non-invasive blood draw, which allows the detection of information about potential prognostic factors, or markers to be used for diagnostic purposes; it might also allow the clinician to establish a treatment regimen and predict a patient’s response. Since the discovery of circulating tumor cells (CTCs) in the nineteenth century, the possibility of integrating LBx into clinical practice has been explored, primarily because of its safeness and easy execution: indeed, compared to solid biopsy, sampling-related risks are less of a concern, and the quickness and repeatability of the process could help confirm a prompt diagnosis or to further corroborate the existence of a metastatic spreading of the disease. LBx’s usefulness has been consolidated in a narrow range of oncological settings, first of all, non-small cell lung carcinoma (NSCLC), and it is now gradually being assessed also in lymphoproliferative diseases, such as acute lymphocytic leukemia (ALL), B-cell lymphomas, and multiple myeloma. The present review aims to summarize LBx’s overall characteristics (such as its advantages and flaws, collection and analysis methodologies, indications, and targets of the test), and to highlight the applications of this technique within the specific field of B-cell malignancies. The perspectives on how such a simple and convenient technique could improve hemato-oncological clinical practice are broadly encouraging, yet far from a complete integration in routine clinical settings.
The Role and Place of Antioxidants in the Treatment of Male Infertility Caused by Varicocele

The inability to become pregnant for at least 1 year despite regular unprotected intercourse may indicate infertility of one or both partners. This problem affects approximately 10–20% of couples worldwide, regardless of race, with male infertility reported to account for 25–60% of cases. Among the most common pathological causes of male infertility is the presence of varicocele and chronic infections of the male reproductive system. This study was performed using data collected at the Genesis Infertility Treatment Clinic, Bydgoszcz, Poland, between 1 January 2015 and 30 June 2017. A total of 163 men meeting the inclusion criteria were selected and divided into the idiopathic infertility group (78 men) and varicocele-related infertility group (85 men). All patients received treatment with a male fertility supplement containing a combination of 1725 mg of L-carnitine fumarate, 500 mg of acetyl-L-carnitine, 90 mg of vitamin C, 20 mg of coenzyme Q10, 10 mg of zinc, 200 µg of folic acid, 50 µg of selenium, and 1.5 µg of vitamin B12 (Proxeed® Plus, Sigma-Tau, Italy) twice a day for a period of 6 months from the time of the diagnosis of infertility. The treatment resulted in significant improvements in general semen parameters, particularly sperm count, sperm concentration, total motility, and progressive motility. This antioxidant therapy produced a particularly marked therapeutic benefit in patients with Grade III varicocele, with a greater improvement in progressive motility than in men with less severe or no varicocele. The use of the antioxidant preparation examined here seems reasonable in men with idiopathic infertility and as an adjuvant in those with varicocele-related infertility in whom surgical treatment has resulted in no improvement. Its use should be considered particularly in patients with Grade III varicocele who do not wish to undergo surgical treatment or in whom such a treatment is not possible for various reasons.
ROTATION PERIODS OF WIDE BINARIES IN THE KEPLER FIELD

In a search of proper motion catalogs for common proper motion stars in the field of the Kepler spacecraft I identified 93 likely binary systems. A comparison of their rotation periods is a test of the gyrochronology concept. To find their periods I calculated the autocorrelation function (ACF) of the Kepler mission photometry for each star. In most systems for which good periods can be found, the cooler star has a longer period than the hotter component, in general agreement with models. However, there is a wide range in the gradients of lines connecting binary pairs in a period–color diagram. Furthermore, near the solar color, only a few stars have longer periods than the Sun, suggesting that they, and their cooler companions, are not much older than the Sun. In addition, there is an apparent gap at intermediate periods in the period distribution of the late K and early M stars. Either star formation in this direction has been variable, or stars evolve in period at a non-uniform rate, or some stars evolve more rapidly than others at the same mass. Finally, using the ACF as a measure of the activity level, I found that while the F, G, and early K stars become less active as their periods increase, there is no correlation between period and activity for the mid K to early M stars.
Atrial Fibrillation Triggered by Adenosine During Fractional Flow Reserve Measurement: Common Arrhythmia in an Uncommon Scenario

Recently, we came across the development of new-onset atrial fibrillation (AF) while performing fractional flow reserve (FFR) for the two patients with borderline lesions of the left anterior descending (LAD) and right coronary arteries (RCA). The use of adenosine for the termination of supraventricular tachycardia is a common indication. The hemodynamic evaluation of a coronary lesion prior to revascularization has grown after the publication of the FAME and FAME 2 trials.1,2 In the catheterization laboratory, intracoronary or intravenous adenosine is used to document the significance of borderline lesions as a vasodilator. Transient bradyarrhythmia is known as an adverse effect. The development of AF following intracoronary or intravenous infusions of adenosine is a rare occurrence.3,4
Entanglement Purification of Nonlocal Quantum‐Dot‐Confined Electrons Assisted by Double‐Sided Optical Microcavities

A nondestructive parity‐check detector (PCD) scheme for two single‐electron quantum dots embedded in double‐sided optical microcavities is presented here. Using a polarization‐entangled photon pair, the PCD works in a parallel style and is robust to the phase fluctuation of the optical path length. In addition, based on this nondestructive PCD, an economic entanglement purification protocol for electron pairs is presented. The parties in quantum communication can increase the purification efficiency and simultaneously decrease the quantum source consumed for some particular fidelity thresholds. Therefore, this protocol has good applications in the future quantum communication and distributed quantum networks.
Quantitative Investigation of the Link between Actin Cytoskeleton Dynamics and Cellular Behavior

Actin cytoskeleton reorganization, which is governed by actin-associated proteins, has a close relationship with the change of cell biological behavior. However, a perceived understanding of how actin mechanical property links to cell biological property remains unclear. This paper reports a label-free biomarker to indicate this interrelationship by using the actin cytoskeleton model and optical tweezers (OT) manipulation technology. Both biophysical and biochemical methods were employed, respectively, as stimuli for two case studies. By comparing the mechanical and biological experiment results of the leukemia cells under electrical field exposure and human mesenchymal stem cells (hMSC) under adipogenesis differentiation, we concluded that β-actin can function as an indicator in characterizing the alteration of cellular biological behavior during the change of actin cytoskeleton mechanical property. This study demonstrated an effective way to probe a quantitative understanding of how actin cytoskeleton reorganization reflects the interrelation between cell mechanical property and cell biological behavior.
Deep Learning Chest CT for Clinically Precise Prediction of Sepsis-Induced Acute Respiratory Distress Syndrome: A Protocol for an Observational Ambispective Cohort Study

Abstract Background: Sepsis commonly causes acute respiratory distress syndrome (ARDS), and ARDS contributes to poor prognosis in sepsis patients. Early prediction of ARDS for sepsis patients remains a clinical challenge. This study aims to develop and validate chest computed tomography (CT) radiomic-based signatures for early prediction of ARDS and assessment of individual severity in sepsis patients. Methods: In this ambispective observational cohort study, a deep learning model, a sepsis-induced acute respiratory distress syndrome (SI-ARDS) prediction neural network, will be developed to extract radiomics features of chest CT from sepsis patients. The datasets will be collected from these retrospective and prospective cohorts, including 400 patients diagnosed with sepsis-3 definition during a period from 1 May 2015 to 30 May 2022. 160 patients of the retrospective cohort will be selected as a discovering group to reconstruct the model and 40 patients of the retrospective cohort will be selected as a testing group for internal validation. Additionally, 200 patients of the prospective cohort from two hospitals will be selected as a validating group for external validation. Data pertaining to chest CT, clinical information, immune-associated inflammatory indicators and follow-up will be collected. The primary outcome is to develop and validate the model, predicting in-hospital incidence of SI-ARDS. Finally, model performance will be evaluated using the area under the curve (AUC) of receiver operating characteristic (ROC), sensitivity and specificity, using internal and external validations. Discussion: Present studies reveal that early identification and classification of the SI-ARDS is essential to improve prognosis and disease management. Chest CT has been sought as a useful diagnostic tool to identify ARDS. However, when characteristic imaging findings were clearly presented, delays in diagnosis and treatment were impossible to avoid. In this ambispective cohort study, we hope to develop a novel model incorporating radiomic signatures and clinical signatures to provide an easy-to-use and individualized prediction of SI-ARDS occurrence and severe degree in patients at early stage.
Fossil group origins: VIII RXJ075243.6+455653 a transitionary fossil group

It is thought that fossil systems are relics of structure formation in the primitive Universe. They are galaxy aggregations that have assembled their mass at high redshift with few or no subsequent accretion. Observationally these systems are selected by large magnitude gaps between their 1st and 2nd ranked galaxies. Nevertheless, there is still debate over whether or not this observational criterium selects dynamically evolved ancient systems. We have studied the properties of the nearby fossil group RXJ075243.6+455653 in order to understand the mass assembly of this system. Deep spectroscopic observations allow us to construct the galaxy luminosity function (LF) of RXJ075243.6+455653 down to M*+ 6. The analysis of the faint-end of the LF in groups and clusters provides valuable information about the mass assembly of the system. In addition, we have analyzed the nearby large-scale structure around this group. We identified 26 group members within r200=0.9 Mpc. The LF of the group shows a flat faint-end slope ( -1.08 +/- 0.33). This low density of dwarf galaxies is confirmed by the low value of the dwarf-to-giant ratio (DGR = 0.99 +/- 0.49) for this system. Both the lack of dwarf galaxies and the low luminosity of the BGG suggests that RXJ075243.6+455653 still has to accrete mass from its nearby environment. This mass accretion will be achieved because it is the dominant structure of a rich environment formed by several groups of galaxies (15) within 7 Mpc from the group center and with +/- 1000$ km/s. RXJ075243.6+455653 is a group of galaxies that has not yet completed the process of its mass assembly. This new mass accretion will change the fossil state of the group. This group is an example of a galaxy aggregation selected by a large magnitude gap but still in the process of the accretion of its mass (Abridged).
Enhancement of Cadmium Phytoremediation Potential of Helianthus annuus L. with Application of EDTA and IAA

The aim of the current study was to assess the cadmium (Cd) phytoremediation potential of Helianthus annuus L. that was exposed to 50, 100, and 150 mg/kg of cadmium for 15, 30, and 60 days with application of EDTA (Ethylenediaminetetraacetic acid) in the soil and IAA (indole acetic acid) as a foliar spray. The results indicated that the concentration, duration of exposure, and amount of Cd affect the phytoremediation potential. The maximum Cd was observed at 60 days (32.05, 16.86, and 10.63%) of Cd application, compared to 15 (2.04, 0.60, and 1.17%) or 30 days (8.41, 3.93, and 4.20%, respectively), in a dose-dependent manner. The application of EDTA in the soil and foliar IAA enhanced the Cd accumulation in the plants at 15, 30, and 60 days of exposure, with maximum accumulation at 60 days. Exposed plants with foliar IAA application showed 64.82%, 33.77%, and 25.84% absorption at 50, 100, and 150 mg/kg, respectively. Apart from higher absorption, the cadmium translocation to the edible part of the plants ceased, i.e., the seeds had 0% accumulation. The interesting fact was recorded that efficient phytoremediation was recorded at 15 days of exposure, whereas maximum phytoremediation was recorded at 60 days of exposure. To minimize the stress, the host also produced stress-related metabolites (i.e., flavonoids, phenolics, proline, and sugar) and antioxidants (i.e., catalases and ascorbate peroxidases). From the current evidence, it could be assumed that the use of EDTA and IAA, along with hyperaccumulating plants, could be a possible green method to remediate Cd-contaminated soil efficiently in a short period of time.
A Firepoint at the Black Hole Singularity

In his original derivation, Hawking showed that a Schwarzschild black hole is unstable at quantum level and it evolves to a final thermal mixed state violating unitarity. There are some attempts to solve this information paradox based on a high energy surface located at the black hole event horizon: the firewall. In the wake of these proposals, we here propose the singularity itself as a "firepoint" capable to break the entanglement between the "int" and the "out" states created through the Hawking process. In this paper the singularity takes active part in the information paradox in two similar ways. In the first way, the singularity, coming in contact with the the "int" state, produces a pure state outside the horizon, but it violates causality allowing people inside the black hole to send signals to the outside. The second way consists of a map that breaks the entanglement between the interior and exterior of the black hole still using the singularity yet without violating causality. The monogamy theorem is not violated whether in the first where the "out" radiation state is rendered pure directly or in the second way where the Page idea is made possible again to solve the information loss problem.
Spatial characterization of photonic polarization entanglement using a Tpx3Cam intensified fast-camera

Scalable technologies to characterize the performance of quantum devices are crucial to creating large quantum networks and quantum processing units. Chief among the resources of quantum information processing is entanglement. Here we describe the full temporal and spatial characterization of polarization-entangled photons produced by Spontaneous Parametric Down Conversions using an intensified high-speed optical camera, Tpx3Cam. This novel technique allows for precise determination of Bell inequality parameters with minimal technical overhead, as well as novel characterization methods of the spatial distribution of entangled quantum information. This could lead to multiple applications in Quantum Information Science, opening new perspectives for the scalability of quantum experiments.
A Face-on Accretion System in High-mass Star Formation: Possible Dusty Infall Streams within 100 AU

We report on interferometric observations of a face-on accretion system around the high-mass young stellar object, G353.273+0.641. The innermost accretion system of 100 au radius was resolved in a 45 GHz continuum image taken with the Jansky-Very Large Array. Our spectral energy distribution analysis indicated that the continuum could be explained by optically thick dust emission. The total mass of the dusty system is ∼0.2 M☉ at minimum and up to a few M☉ depending on the dust parameters. 6.7 GHz CH3OH masers associated with the same system were also observed with the Australia Telescope Compact Array. The masers showed a spiral-like, non-axisymmetric distribution with a systematic velocity gradient. The line-of-sight velocity field is explained by an infall motion along a parabolic streamline that falls onto the equatorial plane of the face-on system. The streamline is quasi-radial and reaches the equatorial plane at a radius of 16 au. This is clearly smaller than that of typical accretion disks in high-mass star formation, indicating that the initial angular momentum was very small, or the CH3OH masers selectively trace accreting material that has small angular momentum. In the former case, the initial specific angular momentum is estimated to be 8 × 1020 ( M☉) cm2 s−1, or a significant fraction of the initial angular momentum was removed outside of 100 au. The physical origin of such a streamline is still an open question and will be constrained by the higher-resolution (∼10 mas) thermal continuum and line observations with ALMA long baselines.
Tachyon matter in loop quantum cosmology

An analytical approach for studying the cosmological scenario with a homogeneous tachyon field within the framework of loop quantum gravity is developed. Our study is based on the semiclassical regime where space time can be approximated as a continuous manifold, but matter Hamiltonian gets nonperturbative quantum corrections. A formal correspondence between classical and loop quantum cosmology is also established. The Hamilton-Jacobi method for getting exact solutions is constructed and some exact power law as well as bouncing solutions are presented.
The progression of students’ views about nature of scientific inquiry

ABSTRACT While helping students develop informed views about nature of scientific inquiry (VNOSI) has been emphasised in science education, little is known regarding students’ current VNOSI at a certain grade level and whether there was evidence of higher attainment of VNOSI in students in higher grades as compared to lower grades? The purpose of this study was to answer these questions. This study was conducted in China, Hebei province, with a medium level of economic, social, and educational development. Data collection consisted of questionnaire survey and structured-interview. Participants were 212 students (82 males, 130 females) at five grade levels and from four types of locations. The results were: (a) No matter which grade levels students were in, most of them had not developed informed VNOSI. (b) According to Fisher exact tests, in six aspects of nature of scientific inquiry (NOSI), students in higher grades had higher attainment as compared to lower grades; and in two aspects of NOSI, students in higher grades did not have higher attainment as compared to lower grades. In order to explain these research results, three possible reasons were explored; For the purpose of promoting the development of students’ VNOSI, three implications were discussed.