Miracle-dz/UniFAR-FTUs huggingface dataset:
IMPORTÂNCIA DA EVOLUÇÃO DOS MÉTODOS DE IONIZAÇÃO À PRESSÃO AMBIENTE EM ESPECTROSCOPIA DE MASSAS NAS ANÁLISES FORENSES

Resumo A Os metodos derivados da ionizacao a pressao ambiente (API) tem sido um avanco na quimica analitica. As tecnicas de ionizacao electrospray ionization (ESI) e sonic-spray ionization (SSI) mudaram o caminho da espectrometria de massas (MS). Um dos metodos de ionizacao discutido neste trabalho, o Easy Ambient Sonic-Spray Ionization (EASI), foi derivado do SSI. A tecnica EASI-MS foi desenvolvida em 2006 pelo fundador e coordenador do laboratorio ThoMSon de Espectrometria de Massas do Instituto de Quimica da Unicamp, o professor Marcos N. Eberlin, e tem-se mostrado eficaz na quimica forense para analise de drogas de abuso, documentos falsos, perfumes, bebidas, entre outros. Descritores: Ionizacao por eletrospray, espectrometria de massas, EASI, quimica forense. IMPORTANCE OF AMBIENTE PRESSURE IONIZATION METHODS EVOLUTION IN MASS SPECTROMETRY IN FORENSIC ANALYSIS Abstract The methods derived from ambient pressure ionization (API) have been a progress in analytical chemistry. The electrospray ionization (ESI) and sonic-spray ionization (SSI) techniques have changed the way of mass spectrometry (MS). One of ionization methods argued in this paper, the Easy Ambient Sonic-Spray Ionization (EASI) was derived from SSI. The EASI-MS technique was developed in 2006 by Mass Spectrometry ThoMSon Unicamp's Chemistry Institute lab founder and coordinator Professor Marcos Eberlin N. and it has been shown effective in forensic chemistry for drug of abuse, counterfeit documents, perfume, alcoholic drink and others. Keywords : Electrospray ionization, mass spectrometry, EASI, forensic chemistry.
Binaural Speech Separation Algorithm Based on Deep Clustering

Neutral network (NN) and clustering are the two commonly used methods for speech separation based on supervised learning. Recently, deep clustering methods have shown promising performance. In our study, considering that the spectrum of the sound source has time correlation, and the spatial position of the sound source has short-term stability, we combine the spectral and spatial features for deep clustering. In this work, the logarithmic amplitude spectrum (LPS) and the interaural phase difference (IPD) function of each time frequency (TF) unit for the binaural speech signal are extracted as feature. Then, these features of consecutive frames construct feature map, which are regarded as the input to the Bi-directional long short-term memory (BiLSTM). The feature maps are converted to the high-dimensional vectors through BiLSTM, which are used to classify the time-frequency units by K-means clustering. The clustering index are combined with mixed speech signal to reconstruct the target speech signal. The simulation results show that the proposed algorithm has a significant improvement in speech separation and speech quality, since the spectral and spatial information are all utilized for clustering. Also, the method is more generalized in untrained conditions compared with traditional NN method e.g., deep neural network (DNN) and convolutional neural networks (CNN) based method.
Intake, Rumen Fermentation and Apparent Digestibility of Aerbasi Cashmere Goats Fed Corn Stover, Caragana and Their Mixture on the Mongolian Plateau

To effectively use local available feed resources to address the problem of animal feed shortage in winter, the intake, rumen fermentation and apparent digestibility of Aerbasi cashmere goats fed corn stover (CS), caragana (CA) and their mixture were studied on Mongolian plateau.The treatments were designed as CS, CA, CS 80% + CA 20% (MT1), CS 50% + CA 50% (MT2), and CS 20% + CA 80% (MT3). With an increased mixing ratio of CA, intake of DM, NDF, and half cellulose was decreased (P<0.05). Meanwhile intake of CP, ADF, and acid detergent lignin (ADL) was increased (P<0.05). Compared to the CS treatment, the proportion of particles ≤ 0.1 mm in size was significantly (P<0.05) higher in the CA treatment. With an increased mixing ratio of CA, the proportions of 0.5–1.0 and 1.0–5.0 mm particles decreased (P<0.05), but the proportion of > 5.0 mm particles did not. the proportions of ≤ 0.1 and 0.1–0.5 mm particles increased (P<0.05). The results confirm the mix ration of 4 to 1 has a good mix ratio for goat feed, based on the DM intake, apparent digestibility and VFA contents, and proportion of particles > 1.0 mm in size.
Detection of the adulteration in pure cow ghee by electronic nose method (case study: sunflower oil and cow body fat)

ABSTRACT Cow ghee is very used in some regions of Iran, such as Kermanshah province. Cow ghee is a natural source that contains high-quality nutrients which are needed for the human body. Adulteration in dairy products is not only a serious threat to human health but also it causes economic losses. Diagnosis of foodstuff cheating and its estimation is one of the key concerns in recent years. The aim of this study was the detection of the adulteration in cow ghee by olfactory machine system. Therefore, an electronic nose system was used for the different levels of sunflower oil and cow body fat mixed with pure cow ghee (10%, 20%, 30%, 40%, and 50%). The principal components analysis (PCA) and artificial neural networks (ANNs) methods were used to achieve this goal. Based on the results, the accuracy of the principal components analysis of sunflower oil and cow body fat were 96% and 97% of the data variance, respectively. According to the results, artificial neural networks identified the adulteration with sunflower oil and cow body fat with an accuracy of 91.3% and 82.5%, respectively.
Unusual reference states for chemical potentials

ABSTRACT The chemical potential of a component in a system is customarily defined as the Gibbs energy of transferring of one mole of this component from a unary reservoir to the system at constant temperature and pressure. The reservoir must contain the component of interest, but there are no physical justifications forbidding a presence of other components in it. A situation when a reservoir is multicomponent rather than unary warrants an analysis. The present study illustrates how the chemical potential of B in a binary A–B substitutional solution can be calculated with respect to the oxide BO. It is demonstrated that the usage of stoichiometric compounds as reference states leads to equilibrium criteria and necessitates an existence of at least one additional reservoir.
Construction and Visible-Light-Driven Photocatalytic Properties of LaCoO3-TiO2 Nanotube Arrays

TiO2 nanotube arrays (NTAs) have high photocatalytic activity; however, their weak visible light absorption limits their solar energy utilization and environmental application. Perovskite (ABO3)-type oxides with a narrow band gap can absorb visible light in a wide wavelength range and have excellent stability; however, their photocatalytic activity is relatively low. Coupling TiO2 NTAs with ABO3 to form heterojunctions is one of the most promising approaches to extend the optical absorption of TiO2 NTAs into the visible-light range and promote the separation rate of photogenerated electron–hole pairs. However, to date, constructing ABO3-TiO2 NTA heterostructured composites has been extremely challenging owing to the different crystallization temperatures of anatase TiO2 NTAs and ABO3. In this work, LaCoO3 nanoparticles were first synthesized using a sol-gel method. The as-prepared LaCoO3 nanoparticles were then modified on the surface of the TiO2 NTAs using an electrophoretic deposition technique, and a series of LaCoO3-TiO2 NTAs photocatalysts were thus constructed by controlling the deposition time. Results of the scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray diffraction (XRD), and X-ray photoelectron spectroscopy (XPS) demonstrated that the nanoparticles prepared through the sol-gel method were LaCoO3 with a uniform size and high crystallization. The average diameter of the LaCoO3 nanoparticles was 100 nm. The binding strength between the LaCoO3 nanoparticles and the TiO2 NTAs was strong. The UV-visible absorption spectra (diffuse reflectance spectroscopy; DRS) demonstrated that the absorption band edge of the LaCoO3-TiO2 NTAs was gradually red-shifted into the visible light region with the increase in electrophoretic time. The LaCoO3-TiO2 NTAs prepared by the electrophoretic deposition technique for 15 min exhibited a strong light absorption in the wide wavelength range from 250 to 700 nm, which was the same as that of the LaCoO3 nanoparticles loaded on a Ti foil. The results of the photocatalytic degradation of methyl orange (MO) under visible light irradiation demonstrated that the photocatalytic degradation rate of MO over LaCoO3-TiO2 NTAs was considerably higher than those of TiO2 NTAs and LaCoO3 nanoparticles loaded on a Ti foil. The LaCoO3-TiO2 NTAs prepared by the electrophoretic deposition technique for 15 min showed the highest photocatalytic degradation rate of MO, which was a four-fold enhancement compared to that of TiO2 NTs under the same conditions. The p-n heterojunctions between the LaCoO3 nanoparticles and the TiO2 nanotubes were responsible for the enhanced visible light photocatalytic activity. The results of the electrochemical impedance spectroscopy (EIS) and photoluminescence spectroscopy (PL) tests demonstrated that the loading of the LaCoO3 nanoparticles effectively promoted the separation and transport of photogenerated charges, thereby enhancing the visible light photocatalytic activity of the TiO2 NTAs.
A path analysis of effects of the career locus of control dimensions and career decision self-efficacy on career aspiration

ABSTRACT This study examined the mediating role of career decision self-efficacy in the relationship between career locus of control and career aspiration. A 9-item Career Aspirations Scale, 31-items Career Locus of Control Scale, and 24-item Career Decision Self-Efficacy Short Form were administered to 2700 students from grades 10 to 11 studying in high schools. Path analysis results indicated that a positive direct effect of the internal locus of control on career aspiration and a negative direct effect of powerful others on career aspiration. Internal control, luck, and powerful others explained 43% of the variation in career decision self-efficacy. The results showed a positive direct effect of career decision self-efficacy on career aspiration. All together internal control, luck, powerful others, and career decision self-efficacy explained 42% of the variation in career aspiration. Implications were discussed to enhance internal locus of control and career self-efficacy among students.
Pyridinium‐Facilitated CO2 Electroreduction on Pt Nanowire: Enhanced Electrochemical Performance in CO2 Conversion

Electrochemical reduction of CO2 to the value‐added fuels is a promising way to mitigate global warming. However, conversion of CO2 to methanol or formic acid is very challenging due to the poor performance of the catalysts employed for the reduction of CO2. In this work, higher performance toward CO2 reduction was obtained when Pt nanowire (Pt NW) assembly is utilized as a co‐catalyst in the electrochemical reduction of CO2 activated by pyridinium (PyrH+). It is found that the overall Faraday efficiency for CO2‐derived products is 55%. The methanol and formic acid were the only detected compounds in aqueous solution using high performance liquid chromatography. Results of this research showed that the higher hydride accumulation on Pt NW and its morphological advancements are two major factors for superior electrochemical performance in CO2 electroreduction. © 2018 American Institute of Chemical Engineers Environ Prog, 38: 112–117, 2019
Natural Product Trienomycin A is a STAT3 pathway inhibitor that exhibits potent in vitro and in vivo efficacy against pancreatic cancer

Background and Purpose: Pancreatic cancer is an exceptionally fatal disease. However, therapeutic drugs for pancreatic cancer have presented a serious shortage over the past few decades. Signal Transducer and Activator of Transcription-3 (STAT3) is persistently activated in many human cancers where it promotes tumor development and progression. Natural products serve as an inexhaustible source of anticancer drugs. Here, we identified the natural product Trienomycin A (TA), an ansamycin antibiotic, as a potential inhibitor of the STAT3 pathway with potent activity against pancreatic cancer. Experimental Approach: Utilizing the STAT3-luciferase (STAT3-luc) reporter system, we found that TA potently inhibits the transcriptional activity of STAT3. We subsequently investigated in vitro and in vivo inhibitory activity of TA against pancreatic cancer and its potential mechanism by using the molecular docking, SPR assay, MTS assay, colony formation assay, transwell migration/invasion assay, flow cytometric analysis, immunofluorescence staining, quantitative real-time PCR, western blotting, tumor xenograft model, H&E staining and immunohistochemistry. Key Results: TA directly bound to STAT3 and inhibited STAT3 (Tyr705) phosphorylation, leading to the inhibition of the STAT3 pathway. TA significantly inhibited the colony formation, proliferation, migration and invasion of pancreatic cancer cell lines. TA dramatically blocked pancreatic tumor growth. More importantly, TA did not show obvious toxicity at the effective dose in mice. Conclusions and Implications: TA exhibits antineoplastic activity by suppressing the STAT3 activation in pancreatic cancer. TA could be a novel therapeutic candidate for pancreatic cancer by blocking the STAT3 pathway.
in the analysis of pesticide residues in

121 10. Cлучик І. Й. Біоіндикація стану довкілля на урбанізованій території за допомогою представників роду Рopulus L. : автореф. дис. канд. біол. наук: 03.00. 16. Чернівці, 2000. 20 с. 11. Стольберг Ф. В. Экология города: Учебник. К. : Либра, 2000. 464 с. 12. Тополиный пух как самый теплый и экологичный наполнитель. URL: https://rodovid.me/soznatelnoe_potreblenie/topolinyy-puh-kak-samyyteplyy-i-ekologichnyy-napolnitel.html. (дата звернення 10.05.2021) 13. Іshchuk L.P., Кrupa N.M. , Priadkina G.O. Characterization of pigment apparatus in leaves of Salicaceae Mirbel species. Ukrainian Journal of Ecology. 2018. No 8 (1). Р. 426-431. doi: 10.15421/2018_231
Antifouling Effect on Biomimetic Metamaterial Surfaces

The snail shells have 200 nm porous structures, and an oil repellent function in water. Three biomimetic structures were fabricated: a silicon black surface, a silicon substrate having nano pillars, and a soft resin sheet having nano pillars. All these structures have equivalent sizes to the real snail shells, and showed good oil repellent effects. The latter two structures have regularly arranged pillars. The last resin sheet was fabricated by using a silicon mold with nano holes and using nanoimprint technologies. As this sheet is soft metamaterial, it can be processed to other shapes. As an example, a tube with oil repellent inner walls was fabricated and evaluated. Good oil repellent and antifouling effect were experimentally obtained from the water-oil mixture flow test. These results indicate the future advances in medical equipment and infrastructure.
Nutrient availability modulating physiology and pathogenicity of Legionella pneumophila

A virulent strain of Legionella pneumophila serogroup 1 was established in continuous culture under defined iron-replete conditions at pH 6.9. Iron-limitation and extremes of pH (6.0 and 7.8) influenced the growth and metabolism of L. pneumophila, as manifested by increased metabolic activity, impaired energy coupling, and altered metabolic fluxes. In particular, the physiological versatility of L. pneumophila was demonstrated by a significant decrease in the iron content of biomass (6-fold increase in Yiron), coupled with reduced metabolic efficiency (Ycarbon), in response to iron-limited growth. Iron limitation promoted the accumulation of significant intracellular reserves of poly- s-hydroxybutyrate (16 % cell dry wt.), which supported long-term survival of L. pneumophila under starvation conditions. Expression of the important pathogenicity factor, the zinc metalloprotease, was regulated by iron availability. Common iron acquisition mechanisms, such as siderophores and transferrin receptors, were not elaborated by iron-limited cells. However, human transferrin was identified as a potential iron source for L. pneumophila, with the zinc metalloprotease mediating transferrin digestion and possibly iron acquisition. Iron-limitation and extremes of pH also influenced cellular morphology and the surface properties of L. pneumophila, promoting the formation of uniform cultures of short rod-shaped bacteria, with altered fatty acid, phospholipid and protein composition. In addition to morphological and physiological adaptation, iron limitation had a significant effect on the virulence of L. pneumophila. Iron-replete cells grown at pH 6.9 and 6.0 were highly virulent in a guinea pig model. However, the virulence of L. pneumophila was significantly attenuated (P < 0.05) in response to iron-limited growth. This phenomenon was reversible, and correlated with reduced phagocytosis and / or reduced intracellular survival following infection. Decreasing the pH of iron-limited cultures to 6.0 did not stimulate recovery of culture virulence. Therefore, this study clearly demonstrates that environmental stresses, including iron limitation and extremes of pH, play an important role in modulating the physiology and virulence of L. pneumophila, inducing the expression of distinct phenotypes differing in their ability to persist in nature and cause infection.
The interface between Macroecology and Conservation: existing links and untapped opportunities

Human activities are altering the structure of ecosystems, compromising the benefits they provide to nature and people. Effective conservation actions and management under ongoing global change rely on a better understanding of socio-ecological patterns and processes across broad spatiotemporal scales. Both macroecology and conservation science contribute to this improved understanding and, while they have different scopes, these disciplines have become increasingly interconnected over time. Here we describe examples of how macroecology has contributed to conservation science, and how conservation science can motivate further macroecological developments and applications. We identify challenges and untapped potential to further strengthen the links between these two disciplines. Major macroecological contributions include developing ecological theory, providing methodologies useful for biodiversity assessments and projections, making data more accessible and addressing knowledge gaps. These contributions have played a major role in the development of conservation science, and have supported outreach to policy makers, media, and the public. Nonetheless, a pure macroecological lens is limited to inform conservation decisions, particularly in local contexts, which frequently leads to the misuse of macroecological analyses for conservation applications, misunderstandings of research outputs, and skepticism among conservation practitioners and scientists. We propose possible solutions to overcome these challenges and strengthen links between macroecology and conservation science, including a stronger focus on ecological mechanisms and predictive approaches, and the creation of hybrid journals and meetings. Finally, we suggest new avenues for macroecological research that would further benefit conservation science.
Cirugía de revisión femoral con vástagos monobloque de recubrimiento completo. Resultados a largo plazo de 78 casos

con-ABSTRACT. Introduction: Loss of bone stock and anatomical alteration of the proximal femur make femoral revision surgery a complex procedure in which the choice of implant will be critical. Our goal is to assess the clinical and radiological results of complete coating Monoblock stems. Material and methods: Retrospective study of 78 consecutive cases of femoral review surgery intervened by our unit. Results: The average follow-up was 122 months. The average score on the Harris Hip Score was 81.2 ± 11.4 points. An age of less than 65 years, a minor femoral defect according to Paprosky classification (I, II and IIIA), the existence of a single previous surgery and the non-occurrence of intra or postoperative complications, was associated with better clinical and functional outcomes (p < 0.05). Cumulative survival was 96.7% at age 10 if we consider as failure the removal of the stem by aseptic loosening and 92% if we consider withdrawal for any cause to fail. Conclusion: Despite the current tendency to use modularity in femoral review surgery and given the results presented, we consider that complete coating monoblock stems provide a firm and stable fixation. However, the worst results in patients with major defects have led to other options being considered.
Synthesis of MgMnSiO4 and Its Application as Cathode Material for Magnesium Battery

Orthosilicate MgMnSiO4 was prepared by sol-gel route and a subsequent heating procedure as a cathode material for rechargeable magnesium batteries. XRD patterns showed that MgMnSiO4 has a orthorhombic system with space group Pbnm(62). MgMnSiO4 presents good electrochemical behaviors at 10 mAg-1 discharge current density with specific capacity 130.1 mAhg-1 after 20 cycles. The results show that MgMnSiO4 could be a potential cathode material for high-energy magnesium secondary battery.
The Correlations Between the Expression of SSTR2, SSTR5 Proteins and Clinicopathological Parameters as well as Prognosis of Gastric Neuroendocrine Neoplasms

Background： Somatostatin receptor 2, 5 (SSTR2, SSTR5) were seldom investigated in gastric neuroendocrine neoplasms (G-NENs). The purpose of the study was to elucidate the expression of SSTR2, SSTR5 in G-NENs and related clinical significance.Methods： 66 paraffin-embedded specimens were obtained from The first affiliated hospital of Zhengzhou university. The expression of SSTR2 and SSTR5 was detected by immunohistochemistry. The expression of SSTR2, SSTR5 and the clinicopathological characteristics, related immunohistochemical molecules and prognosis of gastric neuroendocrine neoplasm were analyzed statistically.Results： The expression rate of SSTR2 protein in G-NENs tissues and normal stomach tissues was 48.5% and 25.0%, respectively (P=0.046); the expression rate of SSTR5 protein in G-NENs tissues and normal stomach tissues was 65.2% and 25.0% , respectively (P=0.018). The expression of SSTR2 was positively correlated with the expression of Ki-67, SSTR5 and tumor grade (P-value was 0.032, 0.002, and 0.005, respectively); the expression of SSTR5 was positively correlated with the expression of SSTR2, Ki-67, CD-56 and tumor grade (P-value was 0.032, 0.011, 0.008, 0.028, respectively). In the SSTR2-positive group, SSTR5, CD-56, Ki-67 were closely related to the prognosis of patients with G-NENs. In the SSTR5-positive group, tumor grade, SSTR2, CD-56, Ki-67 were closely related to the prognosis of patients with G-NENs. Multi-factor analysis showed that SSTR2 and SSTR5 were independent prognostic factors for patients with G-NENs. Conclusion. High expression of SSTR2 and SSTR5 protein was related to the tumorigenesis of G-NENs. SSTR2 and SSTR5 were associated with the prognosis and might improve the prognosis of G-NENs.