Miracle-dz/UniFAR-FTUs huggingface dataset:
Patterns of Trauma Deaths in an Accident and Emergency Unit

Abstract Introduction: Trauma is a leading cause of death in most countries. Different patterns of trauma deaths are recorded in different countries. The purpose of this study was to evaluate retrospectively the pattern of trauma deaths in the emergency unit of a University Teaching Hospital in Nigeria. Methods: This is a descriptive, retrospective study. The data were obtained from patient case files and nurses'records. The data abstracted included age, sex, cause of trauma/death, parts of the body injured, time of death, andthe duration of stay in the Accident and Emergency Unit (AEU). Results: A total of 5,537 cases presented to the AEU of the University of Benin Teaching Hospital between 01 January 2001 and 31 December 2004. Of these, 5,446 were due to trauma (98.4%). A total of 127 patients died (case fatality rate: 2.3%). Of the deaths, 81.9% were males. Motor vehicle crashes were the most frequent cause (54.3%), and drowning was the least common cause of trauma (0.8%). The most frequently injured region of the body was the head and neck (53.4%). A total of 67.4% of the deaths occurred within six hours of presentation to the AEU. Conclusions: There is a great need for improved road safety, adequate pre-hospital medical care, and prompt transfer services for victims of trauma.
Non-identifier based adaptive control scheme with guaranteed stability

In this paper, we investigate a non-identifier based adaptive control scheme for single-input single-output (SISO) plants. The overall adaptive control system can be viewed as a feedback interconnection of a SISO plant, a set of candidate controllers and a non-identifier based adaptive scheme that supervises the switching process among the candidate controllers. The adaptive scheme is designed without any explicit assumptions on the plant model, and the closed-loop system is guaranteed to be stable as long as at least one of the candidate controllers is stabilizing. The basic idea has been investigated by Safonov et al., but the candidate controllers are limited to be "stably causally left invertible" (SCLI). In this paper, we show that stronger stability results can be achieved by properly resetting controller states. Furthermore, the requirement for SCLI is eliminated for the case where all the subsystems are linear time invariant (LTI)
Physics and chemistry of icy particles in the universe : answers from microgravity

During the last century, the presence of icy particles throughout the universe has been con:rmed by numerous ground and space based observations. Ultrathin icy layers are known to cover dust particles within the cold regions of the interstellar medium, and drive a rich chemistry in energetic star-forming regions. The polar caps of terrestrial planets, as well as most of the outer-solar-system satellites, are covered with an icy surface. Smaller solar system bodies, such as comets and Kuiper Belt Objects (KBOs), contain a signi:cant fraction of icy materials. Icy particles are also present in planetary atmospheres and play an important role in determining the climate and the environmental conditions on our host planet, Earth. Water ice seems universal in space and is by far the most abundant condensed-phase species in our universe. Many research groups have focused their eAorts on understanding the physical and chemical nature of water ice. However, open questions remain as to whether ices produced in Earth’s laboratories are indeed good analogs for ices observed in space environments. Although temperature and pressure conditions can be very well controlled in the laboratory, it is very diDcult to simulate the time-scales and gravity conditions of space environments. The bulk structure of ice, and the catalytic properties of the surface, could be rather diAerent when formed in zero gravity in space. The author list comprises the members of the ESA Topical Team: Physico-chemistry of ices in space. In this paper we present recent results including ground-based experiments on ice and dust, models as well as related space experiments performed under microgravity conditions. We also investigate the possibilities of designing a new infrastructure, and /or making improvements to the existing hardware in order to study ices on the International Space Station (ISS). The type of multidisciplinary facility that we describe will support research in crystal growth of ices and other solid refractory materials, aerosol microphysics, light scattering properties of solid particles, the physics of icy particle aggregates, and radiation processing of molecular ices. Studying ices in microgravity conditions will provide us with fundamental data on the nature of extraterrestrial ices and allow us to enhance our knowledge on the physical and chemical processes prevailing in diAerent space environments. 2003 Elsevier Science Ltd. All rights reserved.
Current Practice and Emerging Molecular Imaging Technologies in Oral Cancer Screening

Oral cancer is one of the most common cancers globally. Survival rates for patients are directly correlated with stage of diagnosis; despite this knowledge, 60% of individuals are presenting with late-stage disease. Currently, the initial evaluation of a questionable lesion is performed by a conventional visual examination with white light. If a lesion is deemed suspicious, a biopsy is taken for diagnosis. However, not all lesions present suspicious under visual white light examination, and there is limited specificity in differentiating between benign and malignant transformations. Several vital dyes, light-based detection systems, and cytology evaluation methods have been formulated to aid in the visualization process, but their lack of specific biomarkers resulted in high false-positive rates and thus limits their reliability as screening and guidance tools. In this review, we will analyze the current methodologies and demonstrate the need for specific intraoral imaging agents to aid in screening and diagnosis to identify patients earlier. Several novel molecular imaging agents will be presented as, by result of their molecular targeting, they aim to have high specificity for tumor pathways and can support in identifying dysplastic/cancerous lesions and guiding visualization of biopsy sites. Imaging agents that are easy to use, inexpensive, noninvasive, and specific can be utilized to increase the number of patients who are screened and monitored in a variety of different environments, with the ultimate goal of increasing early detection.
Interventions to change health behaviours: evidence-based or evidence-inspired?

This critical review assesses whether evaluation studies can answer three key questions about behaviour change interventions: ‘Do they work? How well do they work? How do they work? ’ Reviews of intervention evaluations are examined, particularly those addressing decreasing unprotected sexual intercourse and smoking. Selection of outcome measures and calculation of effect sizes are discussed. The article also considers the extent to which evaluation reports specify (i) discrete intervention techniques and (ii) psychological mechanisms that account for observed behavioural change. It is concluded that intervention descriptions are often not specific about the techniques employed and that there is no clear correspondence between theoretical inspiration and adoption of particular change techniques. The review calls for experimental testing of specific theory-based techniques, separately and in combination.
C-Reactive Protein in Idiopathic Inflammatory Myopathies

Abstract Objectives: To characterize C-reactive protein [CRP] in polymyositis [PM], dermatomyositis [DM], Jo-1 syndrome [Jo-1] and sporadic inclusion body myositis [sIBM]. Methods: C-reactive protein obtained before the start of immunosuppressive therapy was analyzed retrospectively in 61 therapy naïve patients [PM n = 27, DM n = 15, Jo-1 n = 5, sIBM n = 14]. All patients had a diagnosis of idiopathic inflammatory myopathy confirmed by muscle biopsy. Results: C-reactive protein was significantly higher in DM and Jo-1 compared to PM and sIBM [ANOVA p < 0.001]. The CRP levels less than twice the upper limit were found in 79% of sIBM patients, 85% of PM patients, 20% Jo-1 of patients, 53% of DM patients. C-reactive protein showed no correlation with creatine kinase and erythrocyte sedimentation rate. Conclusions: The CRP is elevated in a minority of patients with myositis, mostly associated with interstitial lung disease and malignancies.
Sinosenecio jishouensis (Compositae), a New Species from north-west Hunan, China

Sinosenecio jishouensis D. G. Zhang, Y. Liu & Q. E. Yang, a new species from north-west Hunan, China, is described and illustrated. This new species is easily distinguishable from all its congeners by having leafy stems, broadly elliptic-lanceolate and pinnately-veined leaves, and achenes without a pappus. Its somatic chromosomes were counted as 2n=48 and 96. A color plate, line drawings, light microscope (LM) photomicrographs of floral microcharacters, and a distribution map are given for the new species.
American Frontline Healthcare Personnel's Access to and Use of Personal Protective Equipment Early in the COVID-19 Pandemic

Supplemental Digital Content is available in the text Objectives: To quantify adequacy of personal protective equipment (PPE) for U.S. healthcare personnel (HCP) at the outset of the COVID-19 pandemic and its association with infection risk. Methods: March–May 2020 survey of the national Nurses’ Health Studies and the Growing Up Today study regarding self-reported PPE access, use, and reuse. COVID-19 endpoints included SARS-CoV-2 tests and COVID-19 status predicted from symptoms. Results: Nearly 22% of 22,232 frontline HCP interacting with COVID-19 patients reported sometimes or always lacking PPE. Fifty percent of HCP reported not needing respirators, including 13% of those working in COVID-19 units. Lack of PPE was cross-sectionally associated with two-fold or greater odds of COVID-19 among those who interacted with infected patients. Conclusion: These data show the need to improve the U.S. infection prevention culture of safety when confronting a novel pathogen.
Drivers of inter-annual variability in Net Ecosystem Exchange in a semi-arid savanna ecosystem, South Africa

Abstract. Inter-annual variability in primary production and ecosystem respiration was explored using eddy-covariance data at a semi-arid savanna site in the Kruger Park, South Africa. New methods of extrapolating night-time respiration to the entire day and filling gaps in eddy-covariance data in semi-arid systems were developed. Net ecosystem exchange (NEE) in these systems occurs as pulses associated with rainfall events, a pattern not well-represented in current standard gap-filling procedures developed primarily for temperate flux sites. They furthermore do not take into account the decrease in respiration at high soil temperatures. An artificial neural network (ANN) model incorporating these features predicted measured fluxes accurately (MAE 0.42 gC/m2/day), and was able to represent the seasonal patterns of photosynthesis and respiration at the site. The amount of green leaf area (indexed using satellite-derived estimates of fractional interception of photosynthetically active radiation fAPAR), and the timing and magnitude of rainfall events, were the two most important predictors used in the ANN model. These drivers were also identified by multiple linear regressions (MLR), with strong interactive effects. The annual integral of the filled NEE data was found to range from −138 to +155 g C/m2/y over the 5 year eddy covariance measurement period. When applied to a 25 year time series of meteorological data, the ANN model predicts an annual mean NEE of 75(±105) g C/m2/y. The main correlates of this inter-annual variability were found to be variation in the amount of absorbed photosynthetically active radiation (APAR), length of the growing season, and number of days in the year when moisture was available in the soil.
Internet background radiation revisited

The monitoring of packets destined for routeable, yet unused, Internet addresses has proved to be a useful technique for measuring a variety of specific Internet phenomenon (e.g., worms, DDoS). In 2004, Pang et al. stepped beyond these targeted uses and provided one of the first generic characterizations of this non-productive traffic, demonstrating both its significant size and diversity. However, the six years that followed this study have seen tremendous changes in both the types of malicious activity on the Internet and the quantity and quality of unused address space. In this paper, we revisit the state of Internet "background radiation" through the lens of two unique data-sets: a five-year collection from a single unused 8 network block, and week-long collections from three recently allocated 8 network blocks. Through the longitudinal study of the long-lived block, comparisons between blocks, and extensive case studies of traffic in these blocks, we characterize the current state of background radiation specifically highlighting those features that remain invariant from previous measurements and those which exhibit significant differences. Of particular interest in this work is the exploration of address space pollution, in which significant non uniform behavior is observed. However, unlike previous observations of differences between unused blocks, we show that increasingly these differences are the result of environmental factors (e.g., misconfiguration, location), rather than algorithmic factors. Where feasible, we offer suggestions for clean up of these polluted blocks and identify those blocks whose allocations should be withheld.
Persistent Expression of Serotonin Receptor 5b Alters Breathing Behavior in Male MeCP2 Knockout Mice

Mutations in the transcription factor methyl-CpG-binding protein 2 (MeCP2) cause the neurodevelopmental disorder Rett syndrome (RTT). Besides many other neurological problems, RTT patients show irregular breathing with recurrent apneas or breath-holdings. MeCP2-deficient mice, which recapitulate this breathing phenotype, show a dysregulated, persistent expression of G-protein-coupled serotonin receptor 5-ht5b (Htr5b) in the brainstem. To investigate whether the persistence of 5-ht5b expression is contributing to the respiratory phenotype, we crossbred MeCP2-deficient mice with 5-ht5b-deficient mice to generate double knockout mice (Mecp2−/y;Htr5b−/−). To compare respiration between wild type (WT), Mecp2−/y and Mecp2−/y;Htr5b−/− mice, we used unrestrained whole-body plethysmography. While the breathing of MeCP2-deficient male mice (Mecp2−/y) at postnatal day 40 is characterized by a slow breathing rate and the occurrence of prolonged respiratory pauses, we found that in MeCP2-deficient mice, which also lacked the 5-ht5b receptor, the breathing rate and the number of pauses were indistinguishable from WT mice. To test for a potential mechanism, we also analyzed if the known coupling of 5-ht5b receptors to Gi proteins is altering second messenger signaling. Tissue cAMP levels in the medulla of Mecp2−/y mice were decreased as compared to WT mice. In contrast, cAMP levels in Mecp2−/y;Htr5b−/− mice were indistinguishable from WT mice. Taken together, our data points towards a role of 5-ht5b receptors within the complex breathing phenotype of MeCP2-deficient mice.
SPATIAL ASSOCIATIONS AND SPECIES COLLOCATION OF DOMINANT TREE SPECIES IN A NATURAL SPRUCE-FIR MIXED FOREST OF CHANGBAI MOUNTAINS IN NORTHEASTERN CHINA

In order to achieve of the spatial association and optimum collocation, a 1-ha natural spruce-fir mixed forest plot which was established on Changbai Mountains, PR China. Diameter at breast height, height, and the crown width of the standing free trees with >1 cm DBH trees were measured, and species were identified. O-ring statistics and the nearest neighbor analysis were applied to test the spatial correlations and distribution of number of dominant species at different vertical layers. We found that: (1) according to the importance values, the top four species were Abies nephrolepis (Trautv.) Maxim. , Picea koraiensis Nakai, Pinus. koraiensis Sieb. et Zucc. and Tilia. amurensis Rupr. ; (2) most of species pairs have positive associations at small scales, while few are no relevance or have negative associations; (3) the number of juveniles and lower layer trees showed positive skewness under the upper layer trees and the maximum number for coniferous species was at a distance 4.5-6.5 m, while it was 6.5-8.5 m for broadleaved species. Our results provide a new insight into the development of reforestation technique in spruce-fir forests in the Changbai Mountains.
Microencapsulation of Bifidobacterium breve to Enhance Microbial Cell Viability in Green Soybean Yogurt

Bifidobacteria, a major bacterial group, have several beneficial impacts on health, such as enhancing the intestinal flora by limiting the colonization of pathogenic microorganisms and stimulating the immune system. As a result, bifidobacteria have been extensively included in various food products. In this study, Bifidobacterium breve TISTR 2130 was microencapsulated using an emulsion technique with sodium alginate and calcium lactate in green soybean milk as wall materials. This study found that microbeads prepared with 2.0% (w/v) sodium alginate and 2.0% (w/v) calcium lactate had the highest microencapsulation efficiency (MEE) of 99.8% ± 0.07%. In addition, the viability of microencapsulated B. breve TISTR 2130 and free cells was evaluated following a simulated gastrointestinal treatment. Microencapsulated B. breve TISTR 2130 showed higher cell viability than free cells under the simulated gastrointestinal conditions. The viability reduction of free cells dropped substantially to zero after 1 h of incubation in simulated gastrointestinal juice (SIJ), while the viable cell count of microencapsulated B. breve TISTR 2130 remained greater than 5 log CFU/mL and the survival rate was greater than 64% at the end of the sequential digestion. During refrigerated storage of green soybean yogurt (GSY) fortified with microencapsulated B. breve, the viability of B. breve TISTR 2130, syneresis, and acidity decreased, while the pH and viscosity increased. Microencapsulated B. breve TISTR 2130 has the potential to be used as a probiotic fortification in GSY since the viability remained above the recommended minimal limit of 6 log CFU/mL for 10 days during refrigerated storage. The present study demonstrated that the optimized microencapsulated B. breve TISTR 2130 sodium alginate matrix could survive the human gastrointestinal tract to provide health benefits and the possibility of incorporation into functional foods.
Impact of the COVID-19 pandemic on the mental health of Greek adults: a cross-sectional survey

Objectives: The coronavirus disease 2019 (COVID-19) pandemic and mitigation measures based on social distancing are expected to have serious adverse effects on mental health. This cross-sectional study aimed to examine self-reported changes in the mental health status of Greek adults. Study design: The current study is a primary research conducted on Greek adults during the first wave of the epidemic (March to April 2020). Methods: A total of 527 individuals participated in an online survey using a validated questionnaire (State-Trait Anxiety Inventory-STAI and DASS-21). Results: The respondents had a moderate mental health status based on the following scores: STAI-S, 45.8; STAI-T, 40.7; depression, 4.6; anxiety, 3.1; and stress, 6.1. Women, younger respondents, those from lower income households, and those living in smaller apartments experienced increased depression, anxiety, and stress. Additionally, infection control practices during the COVID-19 pandemic such as the use of masks, gloves, and antiseptic can drastically decrease the prevalence of mental health illnesses. Conclusions: These findings can be used by the Greek State to reduce the effects of COVID-19 on the mental health of the population and protect socially vulnerable groups.
www.ssoar.info Efficacy and safety of atomoxetine as add-on to psychoeducation in the treatment of attention deficit/ hyperactivity disorder

Nutzungsbedingungen: Dieser Text wird unter dem "PEER Licence Agreement zur Verfügung" gestellt. Nähere Auskünfte zum PEER-Projekt finden Sie hier: http://www.peerproject. eu Gewährt wird ein nicht exklusives, nicht übertragbares, persönliches und beschränktes Recht auf Nutzung dieses Dokuments. Dieses Dokument ist ausschließlich für den persönlichen, nicht-kommerziellen Gebrauch bestimmt. Auf sämtlichen Kopien dieses Dokuments müssen alle Urheberrechtshinweise und sonstigen Hinweise auf gesetzlichen Schutz beibehalten werden. Sie dürfen dieses Dokument nicht in irgendeiner Weise abändern, noch dürfen Sie dieses Dokument für öffentliche oder kommerzielle Zwecke vervielfältigen, öffentlich ausstellen, aufführen, vertreiben oder anderweitig nutzen. Mit der Verwendung dieses Dokuments erkennen Sie die Nutzungsbedingungen an. Terms of use: This document is made available under the "PEER Licence Agreement ". For more Information regarding the PEER-project see: http://www.peerproject. eu This document is solely intended for your personal, non-commercial use.All of the copies of this documents must retain all copyright information and other information regarding legal protection. You are not allowed to alter this document in any way, to copy it for public or commercial purposes, to exhibit the document in public, to perform, distribute or otherwise use the document in public. By using this particular document, you accept the above-stated conditions of use.
Influence of impulse noise on noise dosimetry measurements on the International Space Station

Abstract Objective: Acoustic dosimetry (AD) data collected on the International Space Station (ISS) were analysed to investigate the impact of impulse noise on crew noise exposure. Design: The noise exposure during work (LAeq16h) and sleep (LAeq8h) time, and the number of impulses >115 dB peak that occurred during each measurement activity, were calculated from the AD data. Two parametric studies were used to estimate the effect of 1) impulses in the original data set, and 2) hypothetical impulses of different levels, durations and quantities on LAeq16h. Study sample: Twelve sets of AD data collected on the ISS from November 2017 to October 2018. Results: The ISS work time noise limit (72 dBA) was exceeded in four of the 12 data sets. In three of those, there were over 100 impulses >115 dB peak and the number of impulses was significantly correlated with LAeq16h. However, the impulses only caused a meaningful increase in LAeq16h when the number of occurrences was large (>50), or when both the level and duration of the impulses were large. Conclusions: Continued monitoring of impulse noise data is recommended to facilitate the investigation of exceedances or abnormalities in future AD data acquired on the ISS.