Miracle-dz/UniFAR-FTUs huggingface dataset:
An Overview of Interfaces for Automated Vehicles (inside/outside) (Deliverable D2.1 in the H2020 MSCA ITN project SHAPE-IT)

This Deliverable starts with a short overview of the design principles and guidelines developed for current Human Machine Interfaces (HMIs), which are predominantly developed for manually driven vehicles, or those with a number of Advanced Driver Assistance Systems (ADAS), at SAE Levels 0 and 1 (SAE, 2018). It then provides an overview of how the addition of more capable systems, and the move to higher levels of vehicle automation, is changing the role the human inside an Automated Vehicle (AV), and the ways in which future automated vehicles at higher levels of automation (SAE level 4 and 5) must communicate with other road users, in the absence of an “in charge” human driver. It is argued that such changes in the role of the driver, and more transfer of control to the AV and its different functionalities, means that there will be more emphasis on the roles and responsibilities of HMIs for future AVs. In parallel, the multifaceted nature of these HMI, presented from different locations, both in and outside the vehicles, using a variety of modalities, and engaging drivers in a two-way interaction, means that a new set of design guidelines are required, to ensure that the humans interacting with AVs (inside and outside the vehicle) are not distracted and overloaded, that they remain situation aware and understand the capabilities and limitations of the system, having the right mental model of system capabilities and their responsibilities, as responsible road users, at all times Following a summary of suggested frameworks and design principles which highlight the significant change needed for new AV HMIs, an overview of results from studies investigating human interaction with internal (or iHMIs), and external (or eHMIs), is provided, with examples of new and innovative methods of communication between humans and their vehicles. The Deliverable then provides a summary of the innovative approaches that will be tackled by the ESRs of the project, which focus on factors such as use of AI and AR for future design of more intuitive and transparent HMI, studying how HMI can support the long term interaction of humans with AVs, and the use of neuroergonomic methods for developing safer HMIs. The Deliverable concludes by summarising how each ESR’s project contributes to the development of HMIs for future AVs.
ASSOCIATIONS BETWEEN IDENTITY AND FUTURE PARENTHOOD AMONG LGBTQ+ ASIAN/PACIFIC ISLANDER AMERICANS

OF DISSERTATION ASSOCIATIONS BETWEEN IDENTITY AND FUTURE PARENTHOOD AMONG LGBTQ+ ASIAN/PACIFIC ISLANDER AMERICANS In recent years, the number of lesbian, gay, bisexual, transgender, and queer (and additional identities; LGBTQ+) identified people and the number of Asian Pacific Islander Americans (APIA) have been increasing in the United States (Movement Advancement Project 2019; Newport, 2018). As the individuals in these demographic groups develop over their lifespan, many will become parents and form families, but little work is currently available on the experiences of LGBTQ+ APIA individuals and future parenthood. Here, I report findings on the perceptions and importance of future parenthood, identity development, identity integration, and microaggressions and/or discrimination (as they relate to racial-ethnic and sexual identity) across three samples: LGBTQ+ APIA, LGBTQ+ White, and cisgender heterosexual people. Taking an intersectional, quantitative approach, I found that broadly, (racial-ethnic and sexual) identity development and integration, as well as experiences of microaggressions or discrimination, were not associated with perceptions and importance of future parenthood among LGBTQ+ APIA individuals. However, there were mixed findings such that racial-ethnic identity development and perceived racial-ethnic discrimination were associated with perceptions and importance of future parenthood, but only among LGBTQ+ White adults. Race-specific microaggressions against APIA were also associated with parenting intentions among cisgender heterosexual APIA people. How these findings can contribute to the foundation of literature on the experiences of LGBTQ+ APIA families and future parenthood is discussed.
Development of a Novel Ferrocenyl Histone Deacetylase Inhibitor for Triple-Negative Breast Cancer Therapy

Owing to the lack of target-directed therapies, triple-negative breast cancer (TNBC) is difficult to effectively treat. In this article, a novel organometallic histone deacetylase (HDAC) inhibitor, Fc-SelSA, based on the selenocyanide (SelSA) zinc-binding motif, was synthesized using a ferrocenyl group as the cap to confer activity against TNBC. The synthesized Fc-SelSA was evaluated for bioactivity in vitro and in vivo. An enzymatic assay showed that Fc-SelSA was a potent HDAC inhibitor with a half-maximum inhibitory concentration (IC50) of 14.8 nM. Molecular docking studies of Fc-SelSA with HDAC suggested that the ferrocenyl unit overlaps with the phenyl group of suberoylanilide hydroxamic acid (SAHA) and the amido group of Fc-SelSA can form hydrogen bonds with the D98 and G151 residues of HDAC, but SAHA and SelSA do not show similar interactions. Moreover, Fc-SelSA reactivated the estrogen receptor alpha (ERα) expression, sensitized TNBC cells to the antagonist tamoxifen, and exerted more potent antitu.
Integrated management systems for better environmental performance and sustainable development a review

The Organizations of the 21st century had evidenced that Management Systems and Standards have become a key aspect for their sustainable development and a prerequisite for their existence. In this recent decade, the Systems for Quality (ISO 9001:2008), Environment (ISO 14001:2004), Occupational Health and Safety (OHSAS 18001:2007), Corporate Social Responsibility (SA 8000:2008 and ISO 26000:2010) and Risk Management (ISO 31000:2009) form the core pillars of the Organization, supplementing the Financial Accounting. High global competition, intense pressure and increasing demand from different stakeholders lead the organization to adopt different Management Systems and Standards (MSS). However, to derive the maximum benefits from implementation and subsequent maintenance of these Systems, it is only a viable and rational attempt that the existing MSS be integrated into a Single Management System. Integrated Management System (IMS) for Quality, Environment, Safety, risk and Corporate Social Responsibility (CSR) is the call of the hour as it can result in considerable benefits including simplified procedures, cost saving and reduction in use of valuable organizational resources. Identification of the key factors affecting IMS, the drivers/motives for IMS implementation and the benefits of integration is a focus of interest for researchers, practitioners, industry and regulatory agencies; paradoxically the literature on IMS is scarce. This paper explores the contents of the literature and reviews on IMS for a better understanding of the content, context and the process of IMS, discusses about the key strategies in IMS design and implementation and briefs on the critical success factors in IMS implementation. This paper also focuses on the organizational drivers/motives for adopting IMS and also the difficulties and challenges in integration.
IN SITU VASCULAR TISSUE REMODELING USING BIODEGRADABLE TUBULAR SCAFFOLDS WITH INCORPORATED GROWTH FACTORS AND CHEMOATTRACTANT MOLECULES

Background Currently, the search for the bioactive molecules capable of promoting formation of the vascular tissue is still ongoing. We have previously demonstrated that incorporation of the growth factors and chemoattractant molecules into the biodegradable tubular scaffolds can increase their primary patency upon the implantation into rat abdominal aorta. However, further studies are required to investigate tissue remodeling using functionalized vascular grafts with the same diameter as a replaced native vessel. Aim To investigate the specific aspects of de novo vascular tissue formation and calcification employing rat abdominal aorta interposition model and vascular grafts with 1.5 mm diameter with incorporated vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF), and stromal cell-derived factor (SDF)-1α. Methods Tubular grafts with a diameter of 1.5 mm were blended of poly(3-hydroxybutyrateco-3-hydroxyvalerate) and poly(ε-caprolactone) (PHBV/PCL). Grafts without growth factors were fabricated using standard electrospinning technique whilst grafts with incorporated growth factors were prepared utilizing emulsion electrospinning. VEGF was incorporated into the inner third, whereas bFGF and SDF-1α were incorporated into the outer two-thirds of the graft. Grafts were implanted into the abdominal aortas of Wistar rats for 1, 3, 6, and 12 months following scanning electron microscopy along with histological and immunofluorescent examination. Results Primary patency of the grafts with VEGF, bFGF, and SDF-1α reached 93% indicative of structural integrity of the vascular tissue. Neither signs of inflammation nor severe calcification was detected. Conclusion As in 2 mm diameter vascular grafts, incorporation of bioactive factors into 1.5 mm diameter grafts increased their long-term primary patency and improved vascular tissue formation in comparison with non-modified grafts.
Moisture transport and sorption in beech and spruce barks

Abstract The bark-water relation and the moisture transport in bark are essential for the living tree but also for the industrial utilization of bark. Thus the bark-water relation of beech (Fagus sylvatica) and spruce (Picea abies) have been studied in the present work. The sorption isotherms were determined at 35°C for both wood and bark and the water diffusivity was measured under steady state conditions (cup method) and under unsteady state conditions, i.e. via sorption test. The sorption isotherms were calculated based on the Hailwood-Horrobin (HH) model. It was observed that beech wood and bark have a similar hygroscopic behavior, whereas spruce bark is more hygroscopic than spruce wood in all the relative humidity (RH) ranges. The radial diffusivity was in the range 1.2·10−11–2.2·10−11 m2 s−1 for spruce and beech bark, respectively, when the driving force of the diffusion is the gradient of bound water.
A list of medicinally important plants of Sikkim Himalayan region, India

According to report of WHO 2019 on Traditional and complementary medicine it is found that more than 80% of the world population out of total global population relies upon natural resources like plants for various formulation in order to treat several diseases. Most of the herbal and pharmaceutical industries were already using some of these plant species commercially as their formulations. These medicinally important plants are also a source for several novel therapeutic compounds and their over exploitation by commercial industries may result in extinction of various plant species which are valuable. People in Himalayan region like Sikkim are utilizing some of this medicinally important plants as part of their local tradition and traditional medicine system. As we already know all of the synthetic allopathic drugs may result in various side-effects and also may cause serious problems like microbial multidrug resistance. So plants with medicinal properties were better choice in for curing various problems of the body. So it is very important to document all these medicinally important plants from Himalayan region of Sikkim. In this article we have utilized Many previous reports about different medicinal plants found in Sikkim Himalayan region and from this list of 51 medicinally important plant species were prepared along with their scientific names, plant parts of interest, and their Ethnomedicinal application or uses which will be helpful for researchers working in related field.
Effluent Quality of Wet Process Coffee Processing Factories in Coffee Growing Ecological Zones in Burundi

Arabica coffee is cultivated by smallholders for commercial purposes, and it is commonly processed using wet Coffee Processing Technology. Burundi has more than 250 Coffee Processing factories which discharge their effluents to water bodies. The goal of this study was to determine the levels of physicochemical parameters in wastewater from Coffee Processing Technology factories in major coffee growing ecological zones in Burundi. Wastewater samples were collected from 19 sites representing private, public and cooperative owned coffee processing stations. Physicochemical analyses were determined in-situ field and laboratory conditions using standard procedures. Results indicate that the wastewater does not meet Burundi Effluent Discharge standards for Total Suspended solids, Chemical Oxygen Demand, Biochemical Oxygen Demand, pH. The data revealed that the wet coffee processing pollutes the environment in terms of pH, Total Suspended solids, Chemical Oxygen Demand, Biochemical Oxygen Demand. There is need to install quality polishing technologies to treat the water before disposal.
How IT Investments Help Hospitals Gain and Sustain Reputation in the Media: The Role of Signaling and Framing

Practice- and Policy-Oriented Abstract Understanding how IT investments help organizations to build and sustain reputation is of particular relevance for healthcare practitioners and policy makers because patients are often unable to assess the quality of care, relying instead on the reputation of health service providers in the media, such as newspapers. As information intermediaries, journalists detect, aggregate, and translate the weaker signals for quality, such as state-of-the-art IT, that a hospital emanates. Our analysis of 152 hospital organizations in England, complemented by interviews with healthcare journalists, shows that journalists write less negatively about hospitals when healthcare organizations’ IT equipment investments are high. This implies that investments in IT equipment can buffer hospitals from negative press, thereby helping them to gain and maintain a strong reputation in the media. Practitioners and policy makers may incorporate the reputational effect of IT when making investment decisions and further amplify such IT investment through press releases, corporate reports, and media interactions.
Evaluation of the Potential Role of Bacillus altitudinis MT422188 in Nickel Bioremediation from Contaminated Industrial Effluents

The incessant pervasiveness of heavy metals in the environment is one of the precursory factors of pollution. This research study was endeavored upon to investigate the bioremediation potential of a nickel (Ni)-resistant bacterial isolate, identified as Bacillus altitudinis MT422188, whose optimum growth parameters were demonstrated at pH 7, temperature 32 °C, and 1 mM phosphate. Minimal Inhibitory Concentration (MIC) and EC50 for Ni were observed to be 20 and 11.5 mM, respectively, whereas the cross heavy-metal resistance was discerned as Cu2+ (25 mM) > Zn2+ (15 mM) > Cr6+ (10 mM) > Pb2+ (5 mM) > Co2+ (8 mM) > Cd2+ (3 mM) > Hg2+ (0 mM). Ni biosorption studies by live and heat-killed bacterial cells were suggestive of Ni uptake being facilitated by an ATP-independent efflux system. A pilot-scale study displayed the effective removal of Ni (70 mg/L and 85 mg/L) at 4- and 8-day intervals, respectively. Moreover, chemotaxis and motility assays indicated the role of Ni as a chemoattractant for bacterial cells. The presence of Ni reduced the GR (0.001 ± 0.003 Ug−1FW), POX (0.001 ± 0.001 Ug−1FW), and SOD (0.091 ± 0.003 Ug−1FW) activity, whereas Sodium dodecyl sulphate—Polyacrylamide gel electrophoresis (SDS-PAGE) revealed the presence of metallothionein (60 kDa). Kinetic and isotherm studies suggested a pseudo second-order and Freundlich model to be better fitted for our study. The thermodynamic parameters (∆H° = 3.0436 kJ/mol, ∆S° = 0.0224 kJ/mol/K) suggested the process to be endothermic, spontaneous, and favorable in nature. FTIR analysis elucidated the interaction of hydroxyl and carboxyl groups with Ni. Scanning Electron Microscopy (SEM) and Energy Dispersive X-Ray Spectroscopy (EDS) demonstrated changes in the morphological and elemental composition of the bacterial cells, which affirmed their interaction with Ni during biosorption. In summary, our study concludes the efficient role of Bacillus altitudinis MT422188 in removing Ni from polluted industrial effluents.
Knowledge, beliefs and perceptions of religious leaders on modern contraceptive use in Burkina Faso: a qualitative study

Introduction in Burkina Faso, despite the strategies implemented to increase the use of contraceptives, the prevalence rate of modern contraceptives remains low. Religion is an important part of the socio-cultural fabric of many communities. Besides, religious leaders play an essential role in adopting and using contraceptive methods to support family health. The study objective was to explore the knowledge, beliefs and perceptions of religious leaders about modern contraceptives among women of childbearing age. Methods data were collected in September 2018 from twenty-one religious' leaders of the urban municipality of Dori. Study participants were selected based on reasoned sampling with maximum variation (sex, religion, age, residence and level of education). We conducted semi-structured individual interviews, non-participant observations and documentary review. Results religious leaders have a good knowledge of modern contraceptive methods, but they prefer traditional contraceptive methods and abstinence. They consider modern contraception as abortion and female sterilization and emphasize birth spacing. Furthermore, religious leaders lack training on contraception and have no real links and exchanges with sexual and reproductive health services. As a result, their assessment of the quality of these services is very mixed. Conclusion religious leaders play a crucial role in improving modern contraceptive methods in Burkina Faso. Close collaboration with family planning services should, at all times, be maintained. The implementation of training and educational activities for religious leaders could help raise modern contraceptive use in Burkina Faso.
Iliocaval stenting – case report

In a 45-year-old man, after a traffic accident with multiple trauma complicated with extensive thrombosis involving the inferior vena cava and iliac veins, rapid devel-opment of severe post-thrombotic syndrome with leg ulcers prevented final orthopaedic reconstructions and recovery. Three years after the accident endovascular reconstruction with venoplasty and stenting of the inferior vena cava and iliac veins was performed. He was successfully treated with the confluence technique, in which dedicated nitinol venous stents were used. After the procedure, collateral circulation disappeared and the ulcers healed. This allowed the end of orthopaedic treatment and rehabilitation. The patient recovered and did not require additional vascular interven-tions for 6 years after the procedure.
An Empirical Study on the Effect of Agricultural Infrastructure Investment on Economic Growth

In this paper, using the panel data of the National Bureau of Statistics database from 2010 to 2019, and using the random effect model, we studied the impact of agricultural infrastructure investment on economic growth. The empirical results show that the investment in agricultural infrastructure can significantly improve the national economy, among which the investment in new infrastructure promotes the economic growth to a certain extent. After comparing the eastern, central and western regions, it is found that the investment in agricultural infrastructure in the western region contributes more to the economic growth, and the statistical results are more significant. Based on the analysis of the role of agricultural infrastructure investment in promoting economic growth, this paper will further discuss the relevant suggestions of the “two new and one heavy” policy in the agricultural field, and promote the adjustment of agricultural industrial structure with the improvement of agricultural infrastructure, and promote the formation of a new development pattern of “double circulation”.
Phase to ground insulation in low voltage machines: lifetime evaluation under enhanced thermal stress

Turn to turn insulation breakdowns are often identified as a primary cause of stator-related failures in rotating electrical machines. However, it is not the interturn short circuit in itself which causes the machine outage, but rather the localised increment in temperature in proximity of the affected turns. If the fault is not promptly detected, the latter can quickly trigger a chain reaction, which eventually degenerates in the puncturing of the interphase or the ground-wall insulation systems. If a machine is designed with features for fault-tolerance, then, a physical and galvanic separation is guaranteed among different phases. Thus, a temperature increment caused by an interturn breakdown is most likely to affect the phase to ground insulation. This paper presents the results of an experimental investigation, whose aim is relating the winding hot-spot temperature with the time to failure caused by a phase to ground short circuit.
Privacy-Preserving Architecture for EV Charging and Billing

The development and deployment of Electric Vehicle (EV) technologies is receiving a great deal of attention from the scientific community, industry representatives, and policy-makers alike. As a result, EV technologies have advanced considerably over the past years and the global adoption rate of EVs is steadily increasing. The past developments in the EV sector, however, were mostly driven by environmental and/or financial goals and have largely neglected the important topics of security and privacy. The lacking consideration of these topics is especially obvious in the processes of EV charging and billing. Due to the highly security- and privacy sensitive nature of these processes, this situation results in an unacceptable level of risk to EV users and is arguably not compliant to contemporary data protection law, i.e., the General Data Protection Regulation (GDPR). This thesis assesses popular, open source EV charging protocols and identifies the involved personal data. Furthermore, a detailed security- and privacy threat analysis is conducted based on the STRIDE (for security) and LINDDUN (for privacy) methodologies showing, for instance, the high risk of an adversary being able to build movement profiles of EV users. In order to address the identified threats, this thesis propose a privacy-preserving architecture for the charging and billing of EVs. The proposed architecture aims to protect the security of an EV user’s payment credentials based on trusted computing methods as well as protect the privacy of users based on a concept for unlinkable charge authorizations. The architecture is designed to provide its protections even under consideration of powerful physical-access adversaries and curious operators while being compatible with the existing definitions of roles and processes in EV charging to the fullest extent possible. The architecture is implemented as a proof-of-concept to show its feasibility and evaluated with respect to the identified threats. The evaluation shows the appropriateness of the solution for the use case, its high degree of compatibility to the current EV charging protocols, and the high level of security- and privacy protections it can provide. The proposed architecture is argued to be an ideal candidate for protecting the charging and billing of EVs especially under consideration of the GDPR’s strict provisions.