Miracle-dz/UniFAR-FTUs huggingface dataset:
Time-division multiplexing of high-resolution x-ray microcalorimeters: Four pixels and beyond

We present experimental results from a four-pixel array of transition-edge-sensor, x-ray microcalorimeters read out through a single amplifier channel via a time-division superconducting quantum interference device multiplexer. We map the dependence of the x-ray energy resolution of the microcalorimeters on multiplexer timing parameters. We achieve multiplexed, four-pixel resolution of 6.94±0.05eV full width at half maximum of the MnKα complex near 5.9keV, which is a degradation of only 0.44eV from nonmultiplexed operation. An analysis of straightforward upgrades to the multiplexer predicts that a linear array of 32 of these pixels could be multiplexed with a degradation in resolution of only 0.1eV. These results, the first demonstration of a time-division multiplexer for x-ray detectors, establish a clear path to the instrumentation of a kilopixel microcalorimeter array.
Solvability sets in pursuit problem with two pursuers and one evader

Abstract The paper deals with a differential game with two pursuers and one evader. Dynamics of each object is described by a stationary linear system of a general type with a scalar control. The payoff is the minimum of two one-dimensional misses between the first pursuer and the evader and between the second pursuer and the evader. The misses are calculated at the instants fixed in advance. A method is described for constructing the level sets of the value function (i.e., the solvability ones for the game under consideration). For the case of “strong” pursuers, the optimal strategies are described. Results of simulations are given. The zero-sum game investigated can be useful for the research of the final stage of a space pursuit, where two pursuing objects and one evader are involved.
Generation of transient cavities in liquids by microsecond pulses of ultrasound

Calculations reported here show that small gas nuclei in a liquid acted on by microsecond ultrasonic pulses may grow into transient cavities that collapse violently. The maximum pressures and temperatures generated by such collapsing cavities are found in these calculations to be of the order of 1000 to 70 000 bars and 1000 ° to 20 000 °K.
Assessing The Environmental Impact of a University Sport Event: The Case of the 75th Italian National University Championships

In recent years, there has been an increase in the attention towards sustainability by the organizing committees of mega-sport events due to the potential impacts they can have. Less attention was given to small-sport events: the carbon footprint of this type of event was seldom investigated unless it had a clear impact on the environment. The purpose of this study is to provide a qualitative-quantitative assessment of the sustainability of a university sporting event held at the University of Cassino and Southern Lazio in 2022. Athletes, technicians, coaches, and companions from various Italian universities were interviewed with the scope being to obtain information on all of the activities associated with the sporting event (travelling, accommodation, etc.). In addition, in-depth interviews were conducted with key members of the organizing committee with the goal of obtaining information relating to the actions undertaken by the Federation to safeguard the environment. The results on the sample indicate a carbon footprint of 40,551 kg of CO2e, of which 27,360 kg of CO2e are attributable to transport and 13,191 kg of CO2e are attributable to accommodations. Sporting event organizing committees should implement some strategies to encourage environmentally friendly behaviours to reduce the negative effects of their activities on the environment.
Foggia Prostate Cancer Risk Calculator 2.0: A Novel Risk Calculator including MRI and Bladder Outlet Obstruction Parameters to Reduce Unnecessary Biopsies

Risk calculator (RC) combining PSA with other clinical information can help to better select patients at risk of prostate cancer (PCa) for prostate biopsy. The present study aimed to develop a new Pca RC, including MRI and bladder outlet obstruction parameters (BOOP). The ability of these parameters in predicting PCa and clinically significant PCa (csPCa: ISUP GG ≥ 2) was assessed by binary logistic regression. A total of 728 patients were included from two institutions. Of these, 395 (54.3%) had negative biopsies and 161 (22.11%) and 172 (23.6%) had a diagnosis of ISUP GG1 PCa and csPCa. The two RC ultimately included age, PSA, DRE, prostate volume (pVol), post-voided residual urinary volume (PVR), and PIRADS score. Regarding BOOP, higher prostate volumes (csPCa: OR 0.98, CI 0.97,0.99) and PVR ≥ 50 mL (csPCa: OR 0.27, CI 0.15, 0.47) were protective factors for the diagnosis of any PCa and csPCa. AUCs after internal validation were 0.78 (0.75, 0.82) and 0.82 (0.79, 0.86), respectively. Finally, decision curves analysis demonstrated higher benefit compared to the first-generation calculator and MRI alone. These novel RC based on MRI and BOOP may help to better select patient for prostate biopsy after prostate MRI.
Coherent states in quaternionic quantum mechanics

We develop Perelomov’s coherent states formalism to include the case of a quaternionic Hilbert space. We find that, because of the closure requirement, an attempted quaternionic generalization of the special nilpotent or Weyl group reduces to the normal complex case. For the case of the compact group SU(2), however, coherent states can be formulated using the quaternionic half-integer spin matrices of Finkelstein, Jauch, and Speiser, giving a nontrivial quaternionic analog of coherent states.
Localized elastic buckling: non-linearities versus inhomogeneities

Buckling of an elastic beam column resting on an inhomogeneous Winkler foundation is revisited from the standpoint of multiscale asymptotic analysis. Despite the complexity posed by the presence of nonlinearity and variable coefficients in the governing eigenproblems, our analytical strategy is shown to capture successfully both the linear and the incipient post-buckling regimes. In particular, the present investigation produces a non-linear amplitude equation with variable coefficients that accounts for the spatial inhomogeneity in the normal restoring force of the foundation. Localization is here due to the spectral properties of the corresponding linearized buckling operator, whereas the role of the non-linearities remains confined to that of amplifying such behaviour.
A Census of Slicings

A band is a closed connected set in the 2-sphere, bounded by one or more disjoint simple closed curves. Consider a band B with bounding curves J1, J2 , … , Jk . On each curve Ji let there be chosen mi ≥ 0 points to be called vertices, with the restriction that the sum of the k integers mi is to be even. Write (1) Next consider a set of n disjoint open arcs in the interior of B which join the 2n vertices in pairs and partition the remainder of the interior of B into simply connected domains. We call the resulting dissection of B a slicing with respect to the given set of vertices. The arcs are the internal edges of the slicing and the simply connected domains are its internal faces, or slices.
On Yosida Approximations of McKean–Vlasov Type Stochastic Evolution Equations

This article is concerned with a semilinear McKean–Vlasov type stochastic evolution equation in a real Hilbert space. The main goal of the article is to study the existence and uniqueness of mild solutions, Yosida approximations of mild solutions of such equations, and to deduce the weak convergence of the corresponding induced probability measures. As an application, we also study the exponential stability of mild solutions of such equations.
Electrospinning of Potential Medical Devices (Wound Dressings, Tissue Engineering Scaffolds, Face Masks) and Their Regulatory Approach

Electrospinning is the simplest and most widely used technology for producing ultra-thin fibers. During electrospinning, the high voltage causes a thin jet to be launched from the liquid polymer and then deposited onto the grounded collector. Depending on the type of the fluid, solution and melt electrospinning are distinguished. The morphology and physicochemical properties of the produced fibers depend on many factors, which can be categorized into three groups: process parameters, material properties, and ambient parameters. In the biomedical field, electrospun nanofibers have a wide variety of applications ranging from medication delivery systems to tissue engineering scaffolds and soft electronics. Many of these showed promising results for potential use as medical devices in the future. Medical devices are used to cure, prevent, or diagnose diseases without the presence of any active pharmaceutical ingredients. The regulation of conventional medical devices is strict and carefully controlled; however, it is not yet properly defined in the case of nanotechnology-made devices. This review is divided into two parts. The first part provides an overview on electrospinning through several examples, while the second part focuses on developments in the field of electrospun medical devices. Additionally, the relevant regulatory framework is summarized at the end of this paper.
Thrombectomy-Capable Stroke Centre—A Key to Acute Stroke Care System Improvement? Retrospective Analysis of Safety and Efficacy of Endovascular Treatment in Cardiac Cathlab

The optimal structure of the acute ischaemic stroke treatment network is unknown and eagerly sought. To make it most effective, different treatment and transportation strategies have been developed and investigated worldwide. Since only a fraction of acute stroke patients with large vessel occlusion are treated, a new entity—thrombectomy-capable stroke centre (TCSC)—was introduced to respond to the growing demand for timely endovascular treatment. The purpose of this study was to present the early experience of the first 70 patients treated by mechanical means in a newly developed cardiac Cathlab-based TCSC. The essential safety and efficacy measures were recorded and compared with those reported in the invasive arm of the HERMES meta-analysis—the largest published dataset on the subject. We found no significant differences in terms of clinical and safety outcomes, such as early neurological recovery, level of functional independence at 90 days, symptomatic intracranial haemorrhage, parenchymal haematoma type 2, and mortality. These encouraging results obtained in the small endovascular centre may be an argument for the introduction of the TCSC into operating stroke networks to increase patient access to timely treatment and to improve clinical outcomes.
The role of relevance, competence, and priors for scalar inferences

Although it is often assumed that the natural language expressions 'some' and 'or' are interpreted according to their first-order logic counterparts, in certain contexts, they receive a narrower interpretation: 'some' is strengthened to 'some, but not all', and 'or' to 'A or B, but not both'. This process is typically explained as an instance of scalar inference. To test this scalar implicature hypothesis, we collect experimental evidence for the effects and interactions of three factors that should affect the robustness of the scalar inferences of 'some' and 'or': the relevance of the stronger alternative, the speaker's competence about the alternative, and the prior probability that the alternative is true. We find that the interpretation of both triggers was affected by speaker competence, but only 'some' was also affected by prior probability, while relevance did not affect either trigger. Ultimately, our results suggest that the interdependence of the three factors is more complex than just the sum of their effects.
Novel Insight into the Role of Squalene Epoxidase (SQLE) Gene in Determining Milk Production Traits in Buffalo

Understanding the genetic mechanisms underlying milk production traits contribute to improving the production potential of dairy animals. Squalene epoxidase (SQLE) is one of the rate-limiting enzymes for cholesterol biosynthesis and was highly expressed in the buffalo mammary. The objectives of the present study were to detect the polymorphisms within SQLE in buffalo, the genetic effects of these mutations on milk production traits, and to understand the gene regulatory effects on buffalo mammary epithelial cells (BuMECs). A total of five SNPs were identified by sequencing, g.18858G > A loci were significantly associated with fat yield, and g.22834C > T loci were significantly associated with peak milk yield, milk yield, fat yield, and protein yield. Notably, linkage disequilibrium analysis indicated that 2 SNPs (g.18858G > A and g.22834C > T) formed one haplotype block, which was found to be significantly associated with milk fat yield, fat percentage, and protein yield. Furthermore, expression of SQLE was measured in different tissues of buffalo and was found to be higher in the mammary. Knockdown of SQLE gene expression significantly affected the growth of BuMECs, including proliferation, cell cycle, and apoptosis, and significantly downregulated the expression of related genes MYC, PCNA, and P21. In addition, knockdown of the SQLE gene significantly reduces triglyceride concentrations and the signal intensity of oil red O staining. In addition, silencing of SQLE was also found to regulate the synthesis and secretion of β-casein and κ-casein negatively. Furthermore, SQLE knockdown is accompanied by the downregulation of critical genes (RPS6KB1, JAK2, eIF4E, and SREBP1) related to milk fat and protein synthesis. The current study showed the potential of the SQLE gene as a candidate for buffalo milk production traits. It provides a new understanding of the physiological mechanisms underlying buffalo milk production regulation.
EFFECTS OF FUNCTIONAL STRENGTH TRAINING ON SPRINTERS’ STRENGTH

ABSTRACT Introduction: The exercise of functional strength in a sprinter can play an essential performance gain to propulsion. Functional training can significantly affect the sprinter, preventing injury and making better use of physical training. The sprint interval training method has been widely recognized and applied. Objective: This paper explores the effect of functional strength training by the sprint interval training method on the strength quality of sprinters. Methods: This paper uses random sampling to select 30 male college sprinters as research subjects. The volunteers were divided into two groups according to the performance of the 100-meter speed project: All the essential data of the subjects who passed the T-test were without statistical difference P>0.05. Both groups perform daily training. Functional strength training was added to the experimental group by interval start training with a full 12-week cycle. The strength data of the athletes were measured before and after the experiment, measured, and discussed statistically. Results: The indicators showed significant differences, except for the normal left supine position support test, unchanged by the presented intervention(P<0.01). After the experiment, all indicators were statistically significant compared to the control group (P<0.01). The performance of the groups in the ball exercise, static jump, and vertical jump was significantly improved (P<0.01). Conclusion: Functional strength exercise can improve sprinters’ body control and stability. The sprint interval method can also improve the speed of upward force transmission. This conclusion is significant for formulating the strength training plan designed for sprinters. Level of evidence II; Therapeutic studies - investigation of treatment outcomes.
Physico-Chemical Parameters, Oxidative Stress, and Fatty Acid Profile of American Pekin Ducks (Anas Platyrhynchos Domesticus) Raised under Different Production Systems

Rearing of American Pekin ducks in different production systems plays a vital role in the determination of the internal climatic conditions of the house for optimum health and meat quality parameters. The experiment was designed to evaluate the influence of different rearing systems fed on kitchen waste on meat quality parameters of American Pekin ducks. A total of 180 ducklings (10 days old) were distributed randomly into three experimental groups; intensive production system (IPS), free-range production system (FRPS), and pool with yard production system (PYPS). We investigate the physicochemical parameters, meat coloration, oxidative stress, and fatty acid (FA) profile of Pekin ducks. Ducks reared in PYPS showed better physico-chemical parameters and meat coloration than those of ducks reared in IPS and FRPS. Drip loss % and cooking loss % are significantly low in FPRS while (L*) l-lightness, (a*) redness, and (b*) yellowness are significantly higher in IPS ( p≤ 0.05). The oxidative stress was reduced in PYPS due to the natural behavior of ducks. Moreover, the fatty acid profile was improved in PYPS fed with 100% kitchen waste. In conclusion, this experiment confirmed that ducks reared in PYPS improve their meat quality parameters, fatty acid, and oxidative stress.
Investigating the central engine of ultraluminous infrared galaxies: near infrared imaging

We present 0.5-arcsec-resolution near-infrared images of six ultraluminous infrared galaxies with known redshifts. Six of the eight bright nuclei are resolved on kiloparsec scales, suggesting that there is significant circumnuclear star formation or close progenitor nuclei. At this spatial resolution, the nuclei have very red colours that cannot in general be reproduced by reddening stellar light, but require an additional component of hot dust emission. In five of the six primary nuclei more than 20 per cent of the K-band continuum originates in hot dust, but the temperature cannot be determined by JHK broad-band colours alone. Comparison with the spectral shapes, however, does allow the temperature to be constrained, and we find in every case that it is at the upper end of the permissible range, ? 1000 K. This does not necessarily imply that there is an active galactic nucleus present, since there is evidence that stellar processes can also generate dust this hot via stochastic heating of small grains. The quantities of hot dust we have found here can make up to 0.5-mag difference to the K-band magnitude even at z ∼ 1, with implications for observations and population synthesis models of higher-redshift objects. Observations in the L or M bands, where hot dust is most important at z ∼ 1, could help to discriminate between models of dusty starbursts and ellipticals.
SABO: Dynamic MPI+OpenMP Resource Balancer

Scientific parallel applications often use MPI for inter-node communications and OpenMP for intra-node orches-tration. Parallel applications such as particle transport, seismic wave propagation simulator, or Finite-Element applications often exhibit workload imbalance due to their nature of ongoing data movement. These applications usually develop software balancing strategies triggered when some imbalance thresholds are detected to reduce this imbalance. These developments are complex to implement and impact the entire distributed applications' performance by synchronizing and exchanging the load over the network. This paper proposes a method to dynamically detect load imbalance and balance the computation by redistributing OpenMP threads between MPI processes local to the node. With minimal impact on the applications' codes, we demonstrate how this technique can improve the overall applications' performance up to 28% on MiniFE, 17 % on Quicksilver, and 3 % on Ondes3D. We also present its impact when executing multiple nodes and our proposed approach's limitations.
Escisión meso-rectal total por vía trans anal (TaTME). Experiencia institucional

Introducción. La cirugía es la base del tratamiento curativo del cáncer de recto. La escisión meso-rectal total ha permitido mejorar los desenlaces oncológicos, disminuyendo las tasas de recurrencia locorregional e impactando en la supervivencia global. El empleo de esta técnica en los tumores de recto medio o distal es un reto quirúrgico, en el que la vía trans anal, permite superar las dificultades técnicas. Método. Se realizó un estudio observacional retrospectivo, recolectando la información de los pacientes con cáncer de recto medio y distal llevados a cirugía con esta técnica, en dos instituciones de cuarto nivel en Medellín, Colombia, entre enero de 2017 y marzo de 2022. Se analizaron sus características demográficas, la morbilidad perioperatoria y la pieza quirúrgica. Resultados. Se incluyeron 28 pacientes sometidos al procedimiento trans anal y laparoscópico de forma simultánea; al 57 % se les realizó una ileostomía de protección. Hubo complicaciones en el 60,7 % de los pacientes; ocurrieron cuatro casos de fuga anastomótica. No se presentó ninguna mortalidad perioperatoria. Conclusiones. La tasa de morbilidad perioperatoria es acorde con lo reportado en la literatura. Se resalta la importancia de la curva de aprendizaje quirúrgica y de incluir la calificación de la integridad meso-rectal dentro del informe patológico. Se requiere seguimiento a largo plazo para determinar el impacto en desenlaces oncológicos, calidad de vida y morbilidad.
Systematic Review of Psychological Interventions for Quality of Life, Mental Health, and Hair Growth in Alopecia Areata and Scarring Alopecia

Alopecia is associated with significant psychological burden. There is limited evidence on the use of psychological interventions in conditions of hair loss. This manuscript systematically reviews the current state of literature on psychological treatments for quality of life, mental health, and hair growth in various forms of alopecia. PubMed and Embase were searched with predefined inclusion and exclusion criteria. Reference lists were also examined for relevant studies. Nine articles met our criteria and are included in this review. Eight of the articles related to alopecia areata and one related to scarring alopecia. Mindfulness-based stress reduction (MBSR) was found to improve quality of life-related subjective symptoms, relationship impacts, anxiety, phobia, distress, and psychological symptom intensity. Alopecia-specific collocated behavioral health (CLBH) treatment showed a trend for psychosocial improvement in areas such as appearance shame, activity avoidance, negative emotions, and coping. Hypnotherapy was found to improve anxiety and depression, quality of life measures, and alexithymia. There was also some evidence for significant hair growth with hypnosis, but the data are mixed. Psychotherapy combined with immunotherapy led to more hair growth, and supported self-confidence. Finally, coping strategies modulated the subjective burden of alopecia, and were associated with disease improvement. Further research will be necessary to better establish the efficacy and optimal administration of these interventions in alopecia.