Miracle-dz/UniFAR-FTUs huggingface dataset:
Effect of Alteration in Precipitation Amount on Soil Microbial Community in a Semi-Arid Grassland

Climate models predict significant changes in precipitation magnitude in semi-arid grasslands, so it is vital to improve our understanding of how changing precipitation affects microbial communities in grassland ecosystems. Using a long-term field manipulation experiment, we evaluated the responses of microbial communities to a decrease (DP) and an increase (IP) in precipitation on a semi-arid grassland in northern China. The results showed that bacterial species richness decreased significantly with DP but remained stable under IP. Relative abundance of oligotrophic, slow-growing bacterial phyla (e.g., Chloroflexi and Acidobacteria) increased with DP but decreased with IP, whereas the relative abundance of copiotrophic, fast-growing bacterial phyla (e.g., Proteobacteria and Bacteroidetes) decreased with DP but increased with IP. In contrast, diversity, species composition, and relative abundance of different fungal phyla change little with DP or IP. These results indicate a greater sensitivity of bacteria to precipitation changes than fungi, and the sensitivity of bacteria to DP was higher than IP. Our findings are important for understanding soil microbial dynamics under future climate change scenarios.
High Plasma sTNF-R1 Level Is Related to Loss of Natural HIV Control in Long-Term Elite Controllers

Human immunodeficiency virus-1 (HIV-1) elite controllers are heterogeneous due to different immunovirological features. We aimed to identify plasma biomarkers associated with loss of spontaneous HIV-1 control in long-term elite controllers (HIV-LTECs). We performed a retrospective study in 60 HIV-LTECs [36 true-LTECs and 24 LTECs losing control (LTECs-LC)]. We selected a plasma sample from true-LTECs (towards the middle of the follow-up period) and two samples from LTECs-LC (one far from the loss of control and another close to loss of control). Plasma biomarkers were evaluated using multiplex immunoassays. The partial least squares-discriminant analysis provided the variable importance in projection (VIP), and the adjusted Generalized Linear Model provided the adjusted arithmetic mean ratio (aAMR). At the moment of the first LTECs-LC samples, the only plasma biomarker with a VIP≥1.5 was sTNF-R1, which showed higher values in LTECs-LC than true-LTECs [aAMR=1.62 (95%CI=1.20-2.19); p=0.001]. After a median of 3.9 (IQR=4.5) years of follow-up from the first sample, we also had access to a second plasma sample from 10 LTECs-LC patients. At the moment of this second LTECs-LC sample, the only plasma biomarker with VIP≥1.5 was also sTNF-R1, which showed higher values in LTECs-LC than true-LTECs [aAMR=1.93 (95%CI=1.41-2.65); p<0.001]. The difference between the first and second samples of LTECs-LC was significant (Δx= 6.58 (95%=0.3; 12.88); p=0.040). In conclusion, high plasma values of sTNF-R1 appear to discriminate HIV-LTECs that lose the natural control of HIV-1, helping to define a specific phenotype that may be useful for the clinical management of these patients.
Drone-Based Position Detection in Sports—Validation and Applications

Radio and video-based electronic performance and tracking systems (EPTS) for position detection are widely used in a variety of sports. In this paper, the authors introduce an innovative approach to video-based tracking that uses a single camera attached to a drone to capture an area of interest from a bird’s eye view. This pilot validation study showcases several applications of this novel approach for the analysis of game and racket sports. To this end, the authors compared positional data retrieved from video footage recorded using a drone with positional data obtained from established radio-based systems in three different setups: a tennis match during training with the drone hovering at a height of 27 m, a small-sided soccer game with the drone at a height of 50 m, and an Ultimate Frisbee match with the drone at a height of 85 m. For each type of playing surface, clay (tennis) and grass (soccer and Ultimate), the drone-based system demonstrated acceptable static accuracy with root mean square errors of 0.02 m (clay) and 0.15 m (grass). The total distance measured using the drone-based system showed an absolute difference of 2.78% in Ultimate and 2.36% in soccer, when compared to an established GPS system and an absolute difference of 2.68% in tennis, when compared to a state-of-the-art LPS. The overall ICC value for consistency was 0.998. Further applications of a drone-based EPTS and the collected positional data in the context of performance analysis are discussed. Based on the findings of this pilot validation study, we conclude that drone-based position detection could serve as a promising alternative to existing EPTS but would benefit from further comparisons in dynamic settings and across different sports.
Saturation Approach to Determine Grazing Mortality in Picoeukaryote and Synechococcus Populations

A substantial component of phytoplankton production in the oceans is channeled through protistan grazers but understanding what dictates the magnitude of this process on a regional and temporal basis is limited, in part, by a shortage of experimental options. A novel saturation approach based on the functional response of planktonic grazers to increasing prey abundance was developed using laboratory cultures of the predator-prey combination of Ochromonas danica and Micromonas pusilla and tested in the coastal waters of the Gulf of Maine. In incubation series, 2 μm polystyrene microspheres were used as surrogate prey to generate increasing levels of saturation of predator ingestion rates of natural prey, resulting in increased rates of apparent growth of the picophytoplankton populations. The relationship between level of addition of surrogate prey to apparent growth, consistently provided significant estimates of maximal growth in the absence of grazing and grazing mortality for populations of picoeukaryotes and Synechococcus. Estimates of gross growth and grazing mortality were comparable to results from dilution experiments carried out in the same waters. The saturation approach represents an additional tool to investigate predator-prey interactions in planktonic communities. Further investigations may show that it can be used to quantify group-specific grazing mortality and growth rates beyond coastal waters and in multiple size classes of prey.
Organization of Presynaptic Autophagy-Related Processes

Brain synapses pose special challenges on the quality control of their protein machineries as they are far away from the neuronal soma, display a high potential for plastic adaptation and have a high energy demand to fulfill their physiological tasks. This applies in particular to the presynaptic part where neurotransmitter is released from synaptic vesicles, which in turn have to be recycled and refilled in a complex membrane trafficking cycle. Pathways to remove outdated and damaged proteins include the ubiquitin-proteasome system acting in the cytoplasm as well as membrane-associated endolysosomal and the autophagy systems. Here we focus on the latter systems and review what is known about the spatial organization of autophagy and endolysomal processes within the presynapse. We provide an inventory of which components of these degradative systems were found to be present in presynaptic boutons and where they might be anchored to the presynaptic apparatus. We identify three presynaptic structures reported to interact with known constituents of membrane-based protein-degradation pathways and therefore may serve as docking stations. These are (i) scaffolding proteins of the cytomatrix at the active zone, such as Bassoon or Clarinet, (ii) the endocytic machinery localized mainly at the peri-active zone, and (iii) synaptic vesicles. Finally, we sketch scenarios, how presynaptic autophagic cargos are tagged and recruited and which cellular mechanisms may govern membrane-associated protein turnover in the presynapse.
IL-4/IL-13 Axis in Allergic Rhinitis: Elevated Serum Cytokines Levels and Inverse Association With Tight Junction Molecules Expression

The IL-4/IL-13 axis is involved in the pathogenesis of allergic rhinitis (AR). In this study, we investigated the serum cytokines levels of IL-4, IL-5, IL-6, and IL-13 in AR patients, and the transcript expression levels of their receptors (i.e. IL4R, IL5RA, IL6R, and IL13RA1) in nasal epithelial cells of AR patients versus non-allergic controls. Nasal epithelial cells and blood samples of non-allergic controls (n = 30) and AR patients (n = 30) were collected to examine mRNA expression and serum cytokines levels, respectively. Bioinformatics analyses of IL-4/IL-13 receptor heterodimer association with tight junction (TJ) and JAK/STAT signaling genes were conducted in a gene expression profiling (GEP) dataset (GSE44037) of AR patients (n = 12) and healthy controls (n = 6). Serum IL-4, IL-5, IL-6 or IL-13 levels, and IL13RA1 transcript expression were significantly higher in AR patients compared with non-allergic controls. IL-4 and IL-13 serum levels were positively correlated with IL13RA1 expression in AR patients but not in non-allergic controls. In the GEP dataset (GSE44037), six TJ (CLDN4, CLDN7, CLDN12, CLDN15, TJP1, and TJP2) genes’ expressions were negatively correlated, respectively, with IL-4Rα/IL-13Rα1 heterodimeric receptor expression in AR patients and not in control samples. These six TJ genes contributed to the significant enrichment of tight junction Gene Ontology (GO ID: 0070160). Lastly, STATs DNA binding motif analysis showed that each of these TJ genes contains STATs binding consensus sequence within intronic and intergenic regions. Our results suggest that increased IL-4/IL-13 serum cytokines levels may contribute to decreased TJs expression via IL-4Rα/IL-13Rα1 heterodimeric receptor in nasal epithelium of AR patients.
Car Recommendation System for Dealers in Different European Countries

Recommendation systems are widely used in all walks of life, This paper is about the design of car recommendation of car rating for different European countries using collaborative filtering(CF). Compared with content-based filtering, collaborative filtering has the advantage that it can recommend items according to the historical information of each user, which has nothing to do with the content attributes of the item itself, which is the reason why we choose CF as our model to develop the recommendation system. The user model is designed using the brand, model, car sales, and country. In this paper, the model gives the similarity between the business pairs. The full model successfully gives the prediction of the top 5 sales cars in each country. The mean square error (MSE) of the whole model is 8.086, while the MSE of both predicts and tests with a rank larger than 3 is 0.4s241379. Without enough data, the MSE of the full model is a bit large. In the future, we could find more countries' car data sets to improve the prediction accuracy and can also try to make a prediction for new markets.
Comparison of Human Body Sizing Measurement Data by Using Manual and 3D Scanning Measuring Techniques

In this paper, we analyzed the data of the 17 body sizing measurement parameters of 300 adult male participants who were Shaanxi adult male aged 20»50, which were collected by using the 3D automatic measurement, 3D interactive measurement and manual measurement. We compared the data of the 3D automatic measurement with those of the 3D interactive measurement and the manual measurement. From the results of the analysis, we can draw the following conclusions: (1) Deviation between the manual measurement and the 3D scanning measurement existed obviously, which cannot be ignored; (2) In the 3D automatic measurement, as the result of the deviation of the identiflcation to the bone location, the measurement data must be checked and modifled interactively; (3) The posture of the participant has a signiflcant efiect on the measurement data, and the specifled basic stance will afiect the measurements of shoulder, breast and waist. Therefore, the scanning posture should be standardized based on the need of the study. For example the stance with feet together can make the height measurement more accurate; (4) Many factors would interfere with the accuracy of the manual measure and result the difierence with 3D measurement, such as the breathing and posture of the participants, and the measurement skill, experience, position mark etc. (5) There is a linear relation between the manual measurement and the 3D scanning measurement. By establishing the linear regression model the measurement data can be forecasted and calculated.
Recursive multiport schemes for implementing quantum algorithms with photonic integrated circuits

We present recursive multiport schemes for implementing quantum Fourier transforms and the inversion step in Grover's algorithm on an integrated linear optics device. In particular, each scheme shows how to execute a quantum operation on $2d$ modes using a pair of circuits for the same operation on $d$ modes. The circuits operate on path-encoded qudits and realize $d$-dimensional unitary transformations on these states using linear optical networks with $O\left(d^2\right)$ optical elements. To evaluate the schemes against realistic errors, we ran simulations of proof-of-principle experiments using a simple fabrication model of silicon-based photonic integrated devices that employ directional couplers and thermo-optic modulators for beam splitters and phase shifters, respectively. We find that high-fidelity performance is achievable with our multiport circuits for $2$-qubit and $3$-qubit quantum Fourier transforms, and for quantum search on four-item and eight-item databases.
Influence of Partial Blocks on Temperature Field Distribu tion for Hollow Strands in Turbo-generator Stator Bar

Based on the heat transfer model of the generator stator bars,the three-dimensional temperature field distribution of the generator stator bar is analyzed in the finite element method.As the object of study,the low er bar of one 600 MW generator stator is analyzed to obtain the temperature distribution w hen the hollow strands are partly blocked.The results show that w hen the hollow strands are blocked,the stator bar's temperature distribution is affected to different extents.With the blockage coefficient increasing,the temperature of the stator bar rises w hen one hollow strand is partly blocked.
Study of left ventricular pressure-volume relations during nitroprusside infusion in human subjects

Studies were made on 21 patients, 8 without any symptoms of left ventricular failure, group 1, and 13 with clinical symptoms ofheart failure, group 2. Cardiac output, mean aortic and left ventricular pressures (using catheter tip micromanometer), and ventricular volume (obtained from left ventricular cineangiograms) were measured before and during nitroprusside infusion. The heart rate did not change in either of the groups. Only in group 2 did cardiac index and stroke volume increase significantly. Mean aortic pressure and total systemic vascular resistance decreased significantly in both the groups. Left ventricular end-diastolic pressure decreased significantly in both the groups, but this decrease was greater in group 2 (9 mmHg compared with 3 mmHg for group 1). The decrease in the left ventricular end-diastolic volume was similar in both the groups. The decrease in left ventricular end-systolic
Qimera: Data-free Quantization with Synthetic Boundary Supporting Samples

Instead of the superposed embeddings, we tried the alternative of adjusting the variance of the noise inputs, as discussed in Section 4.1 of the main body. We have tested five values as standard deviation σz: 0.25, 0.5, 1.0, 1.5, and 2.0. The results in Table 6 show that as we hypothesized, just by increasing the noise level did not provide much improvement on the performance of the baseline. Instead, we have noticed a slight improvement on GDFQ when the noise level is decreased, and we believe this is due to the generation of clearer samples. Nonetheless, the accuracy is far below that of the proposed Qimera.
Refining the Diagnosis of Cognitive Complaints in Schizophrenia

Introduction.Neurocognitive deficit (NCD) in schizophrenia is considered as the "third group of symptoms" along with positive and negative disorders. It is believed that neurocognitive deficit largely determines the social and therapeutic prognosis of the disease, and also affects the formation of other psychopathological symptoms [24]. The latest advances in molecular biology, genetics, and neuroimaging, together with the accumulated knowledge about the significant similarity of the clinical manifestations of these two endogenous mental disorders, the commonality of diagnostic and therapeutic principles, make us think about changing our ideas about the dichotomous model of endogenous psychoses [22]. One of the factors that initiated the revision of these concepts are data from studies of cognitive impairments in patients with endogenous psychoses. It was the separation of cognitive deficits into a separate cluster of disorders, first in schizophrenia, and then in affective psychosis, that caused a new wave of interest in neuroimaging research and coincided with the latest advances in molecular genetics, which allowed researchers to gain a new look at many previously considered unshakable postulates . Cognitive dysfunction, as evidenced by the results of numerous studies, is one of the central links in the etiopathogenesis of schizophrenia, and therefore it can be distinguished into a separate pathological cluster, by analogy with positive and negative symptoms [20]. Cognitive decline in patients with schizophrenia precedes the development of mental illness and is a genuinic disruption in the flow of information processes. The need to take cognitive impairments into account in experimental psychological studies of schizophrenia was noted in many works, for example, E. R. Isaeva showed that for the choice of constructive coping with stress, an adequate cognitive assessment of the social situation is important [12]. In cognitive impairment, according to VG Morogin, it is necessary to take into account the motivational side of cognitive processes in schizophrenia [13]. Thus, according to foreign authors, the basic cognitive functions include memory, attention and performance functions. There are several types of cognitive impairments: I type of impairment is associated with the functions of attention: concentration, stability and selectivity, decreased purposefulness of activity, etc. II type of impairment is associated with mnestic functions: visual and auditory speech memory, reduced accuracy when copying, etc. III the type of impairment 1. Mukhamadieva Nigina Bakhodirovna
Correlation between Rockwell and Brinell Hardness Measurements

There exist various types of experimental measurement of hardness, yet a unified understanding of various hardness measurements lacks. Here, by testing the hardness of a wide range of materials, we show that Rockwell and Brinell hardness tests, the two most used hardness measurements, are closely related. The experimental measurements agree well with the theoretical prediction of such a correlation, which is further validated by finite element simulations. The findings of the correlation between Rockwell and Brinell hardness help address the challenges in measuring the hardness of certain materials.
Assessment of the Global Rating of Knee Function in Patients Following Anterior Cruciate Ligament Reconstruction

Objective: The purpose of this study was to assess the validity of the global rating of knee function as a measure of participation restrictions experienced during activities of daily living and sports by patients with a history of anterior cruciate ligament reconstruction (ACLR). Design: Cross-sectional study. years), at a mean of 31.2 ± 14.4 months following ACLR, participated in this study. During testing, subjects were first asked to provide a global rating of function by assessing their level of knee function on a 0 to 100 scale, with 0 points representing complete loss of function due to their knee injury and 100 points representing their level of function prior to their knee injury. After providing a global rating of function, subjects completed the Knee Outcome Survey (KOS) Activities of Daily Living Scale (ADLS) and Sports Activity Scale (SAS), which served as the measure of participation restrictions in this study. Results: Pearson product correlations revealed moderate relationships between the global rating of function and the ADLS (r ＝ 0.66, p ＜ 0.0001) and SAS (r ＝ 0.69, p ＜ 0.0001). Conclusions: The global rating of knee function provides a valid measure of participation restrictions experienced during activities of daily living and sports by patients with a history of ACLR.
Association Between Thromboelastography and Coronary Heart Disease

Background Thromboelastography (TEG) is a novel blood viscoelasticity detection method revealing blood coagulation status and has been reported to be helpful in predicting clinical outcomes in patients with cardiovascular diseases (CVD). In this study, we aimed to investigate the association between TEG and CVD. Material/Methods A single-center case-control study was performed. Individuals who took TEG tests at Tongji Hospital in Wuhan, China from 2015 to 2019 were included. The nearest-neighbor Mahalanobis matching with replacement, within propensity score calipers of 0.25 was used to control the covariate imbalance between CVD patients and controls. Logistic regression analyses were conducted to assess the relationship between TEG and CVD. Subgroup and sensitivity analyses were performed to evaluate the robustness of the association between TEG and CVD. Results After matching, a total of 151 participants were included in this study, with 83 patients having CVD (49 patients having coronary heart disease [CHD] and 34 patients having an ischemic stroke). By comparison, CHD patients had a significantly higher maximum amplitude (MA) (P=0.02) than controls. After multivariable adjustment, MA (OR 1.11, 95% CI 1.01–1.24, P=0.04) was independently associated with CHD. The association between MA and CHD remained robust across subgroups and in sensitivity analyses. Conclusions The current study suggests that MA is significantly associated with CHD. Enhanced platelet reactivity as described by high MA might be associated with risk of CHD. The exact role of MA in the measurement of CHD risk needs to be further examined in large-scale prospective cohort studies.
Bound states in the continuum on flatbands of symmetry-broken photonic crystal slabs

Bound states in the continuum (BICs) are localized states despite in a radiation continuum, rendering the ultra-high quality factor for enhanced light–matter interactions and supporting exotic topological properties. So far, most of studied BICs in photonic crystal (PhC) slabs are only vertically localized, i.e. allowing propagations in the plane of slab therein but forbidding radiations, and the density of optical states (DOS) at their frequencies is limited due to the steep dispersion characteristics. Here, we report a BIC existing on a flatband of symmetry-broken PhC slab. The flatband, associated with largely reduced group velocity, significantly sharpens the DOS at the frequency of BIC, which can be realized via finely controlling broken vertical symmetry in the PhC slab. The effect of broken symmetry is revealed in a simple effective Hamiltonian near the second-order Γ point of such system. Our results show the simultaneous engineering of dispersion and leaky characteristics of modes, offering new opportunities to boost light–matter interactions and to enhance the performance of photonic devices.