Miracle-dz/UniFAR-FTUs huggingface dataset:
A Faster Maximum Cardinality Matching Algorithm with Applications in Machine Learning

Maximum cardinality bipartite matching is an important graph optimization problem with several applications. For instance, maximum cardinality matching in a δ -disc graph can be used in the computation of the bottleneck matching as well as the ∞ -Wasserstein and the Lévy-Prokhorov distances between probability distributions. For any point sets A, B ⊂ R 2 , the δ -disc graph is a bipartite graph formed by connecting every pair of points ( a, b ) ∈ A × B by an edge if the Euclidean distance between them is at most δ . Using the classical Hopcroft-Karp algorithm, a maximum-cardinality matching on any δ -disc graph can be found in ˜ O ( n 3 / 2 ) time. 2 In this paper, we present a simpliﬁcation of a recent algorithm (Lahn and Raghvendra, JoCG 2021) for the maximum cardinality matching problem and describe how a maximum cardinality matching in a δ -disc graph can be computed asymptotically faster than O ( n 3 / 2 ) time for any moderately dense point set. As applications, we show that if A and B are point sets drawn uniformly at random from a unit square, an exact bottleneck matching can be computed in ˜ O ( n 4 / 3 ) time. On the other hand, experiments suggest that the Hopcroft-Karp algorithm seems to take roughly Θ( n 3 / 2 ) time for this case. This translates to substantial improvements in execution time for larger inputs.
A randomized -approximation algorithm for the minimum vertex cover problem

Vertex cover problem is a famous combinatorial problem, which its complexity has been heavily studied over the years and we know that there is not any mathematical formulation that approximates it better than . In other words, it is known that it is hard to approximate to within any constant factor better than , while a -approximation for it can be trivially obtained. In this paper, by a combination of a well-known semidefinite programming formulation and a rounding procedure, along with satisfying new properties, we introduce an approximation algorithm for the vertex cover problem with a performance ratio of on arbitrary graphs, en route answering an open question about the unique games conjecture.
Review of smart robots for fruit and vegetable picking in agriculture

The fruit and vegetable picking has posed a great challenge on the production and markets during the harvest season. Manual picking cannot fully meet the rapid requirements of each market, mainly due to the high labor-intensive and time-consuming tasks, even the aging and shortage of agricultural labor force in recent years. Alternatively, smart robotics can be an efficient solution to increase the planting areas for the markets in combination with changes in cultivation, preservation, and processing technology. However, some improvements still need to be performed on these picking robots. To document the progress in and current status of this field, this study performed a bibliometric analysis. This analysis evaluated the current performance characteristics of various fruit and vegetable picking robots for better prospects in the future. Five perspectives were proposed covering the robotic arms, end effectors, vision systems, picking environments, and picking performance for the large-scale mechanized production of fruits and vegetables in modern agriculture. The current problems of fruit and vegetable picking robots were summarized. Finally, the outlook of the fruit and vegetable picking robots prospected from four aspects: structured environment for fruit planting, the algorithm of recognition and positioning, picking efficiency, and cost-saving picking robots. This study comprehensively assesses the current research status, thus helping researchers steer their projects or locate potential collaborators.
Verba Volant, Scripta Volant: Understanding Post-publication Title Changes in News Outlets

Digital media (including websites and online social networks) facilitate the broadcasting of news via flexible and personalized channels. Unlike conventional newspapers which become “read-only” upon publication, online news sources are free to arbitrarily modify news headlines after their initial release. The motivation, frequency, and effect of post-publication headline changes are largely unknown, with no offline equivalent from where researchers can draw parallels. In this paper, we collect and analyze over 41K pairs of altered news headlines by tracking ∼ 411K articles from major US news agencies over a six month period (March to September 2021), identifying that 7.5% articles have at least one post-publication headline edit with a wide range of types, from minor updates, to complete rewrites. We characterize the frequency with which headlines are modified and whether certain outlets are more likely to be engaging in post-publication headline changes than others. We discover that 49.7% of changes go beyond minor spelling or grammar corrections, with 23.13% of those resulting in drastically disparate information conveyed to readers. Finally, to better understand the interaction between post-publication headline edits and social media, we conduct a temporal analysis of news popularity on Twitter. We find that an effective headline post-publication edit should occur within the first ten hours after the initial release to ensure that the previous, potentially misleading, information does not fully propagate over the social network.
Secure Video Communication For Defense Applications

: The aim of this review is to use the video file as a cover carrier in the study of steganography methods. A video file consisting of separated images and audio files which is video based steganography is used more as it is more eligible than other multimedia files. The advantages of using the video file as a cover carrier for steganography has been proposed as a result of this study. Hiding confidential information within any media is called as Steganography technique. Since Steganography and cryptography are similar in the way that they both are used to protect confidential information, there is a confusion between them. The difference between the two is in the appearance in the processed output; the output of cryptography draws the attention since it is scrambled whereas in Steganography the output is not apparently visible. In this article we have tried to elucidate the different approaches towards implementation of using ‘multimedia’ file (text, static image, audio and video) and Network IP datagram as cover in steganography. Some steganalysis methods will also be discussed.
Field evaluation of a novel, rapid diagnostic assay, and molecular epidemiology of enterotoxigenic E. coli among Zambian children presenting with diarrhea

Background Enterotoxigenic Escherichia coli (ETEC) is one of the top aetiologic agents of diarrhea in children under the age of 5 in low-middle income countries (LMICs). The lack of point of care diagnostic tools for routine ETEC diagnosis results in limited data regarding the actual burden and epidemiology in the endemic areas. We evaluated performance of the novel Rapid LAMP based Diagnostic Test (RLDT) for detection of ETEC in stool as a point of care diagnostic assay in a resource-limited setting. Methods We conducted a cross-sectional study of 324 randomly selected stool samples from children under 5 presenting with moderate to severe diarrhea (MSD). The samples were collected between November 2012 to September 2013 at selected health facilities in Zambia. The RLDT was evaluated by targeting three ETEC toxin genes [heat labile toxin (LT) and heat stable toxins (STh and STp)]. Quantitative PCR was used as the “gold standard” to evaluate the diagnostic sensitivity and specificity of RLDT for detection of ETEC. We additionally described the prevalence and seasonality of ETEC. Results The study included 324 participants, 50.6% of which were female. The overall prevalence of ETEC was 19.8% by qPCR and 19.4% by RLDT. The children between 12 to 59 months had the highest prevalence of 22%. The study determined ETEC toxin distribution was LT 28/321(9%), ST 18/321(6%) and LT/ST 16/321(5%). The sensitivity and specificity of the RLDT compared to qPCR using a Ct 35 as the cut-off, were 90.7% and 97.5% for LT, 85.2% and 99.3% for STh and 100% and 99.7% for STp, respectively. Conclusion The results of this study suggest that RLDT is sufficiently sensitive and specific and easy to implement in the endemic countries. Being rapid and simple, the RLDT also presents as an attractive tool for point-of-care testing at the health facilities and laboratories in the resource-limited settings.
Discontinuing Antipsychotic Medication After Remission from First-Episode Psychosis: A Survey of Psychiatrists’ Attitudes in Taiwan

Background Patients in remission after first-episode psychosis are inclined to discontinue antipsychotic treatment, which may lead to higher risk of relapse and unfavorable outcomes. Paradoxically, also there are evidences suggesting that certain patients may stay well in drug-free condition. Psychiatrists’ views towards this dilemma might affect their approaches to these patients, and discrepant attitudes are noted between Western and Asian clinicians. This study aimed to examine psychiatrists’ attitudes about discontinuing antipsychotic medications after remission from first-episode psychosis. Methods Psychiatrists were recruited for this study using convenience sampling. A cross-sectional survey was conducted using a set of questionnaires comprising nine items for attitudes toward medication discontinuation, six vignettes for probing psychiatrists’ practice in designated clinical scenarios, and a list of criteria that may affect their responses. Results Responses were provided by 118 psychiatrists, two-thirds men, mean age 39.8 ± 10.1 years and mean experience 12.7 ± 9.7 years. Half of the participants endorsed that fewer than 20% of the remitted patients should stop medication completely; the majority advised that an observation period of 1 year or longer is necessary while discontinuing medication. The majority would not initiate discussion with patients about discontinuing medication. Responding to two case vignettes, those who endorsed that more patients could stop antipsychotics were also more inclined to discuss it with patients, but not consistently in response to the other four case vignettes. Taiwan psychiatrists expressed a wide range of decision-making considerations for discontinuing antipsychotics. Conclusion The majority of Taiwan psychiatrists thought it was not feasible to stop medications completely but were willing to consider this option. Once being presented with actual clinical scenarios, many participants hesitated to discontinue antipsychotic medications for various reasons. The proactive attitude of psychiatrists towards conducting clinical trials to test the feasibility of medication discontinuation may help to provide better reference for this clinical dilemma.
Racial disparities in the association between resilience and ART adherence among people living with HIV: the mediating role of depression

ABSTRACT Research examining the mediating role of depressive symptoms in the association between resilience and antiretroviral therapy (ART) adherence is lacking. Therefore, this study aims to examine the mediating role of depression between resilience and ART adherence, as well as to explore whether this relationship varies across racial background. A total of 327 people living with HIV and on ART in South Carolina were surveyed about their ART adherence and mental health, including resilience and depressive symptoms. Path analyses were conducted to determine the direct and indirect effects between resilience, depressive symptoms, and ART adherence. After adjusting for age, gender, income, education, employment and time since diagnosis, among Black individuals, resilience was negatively associated with depressive symptoms (β = -−0.248, p < 0.001); depressive symptoms were negatively associated with ART adherence (β = −0.166, p = 0.020); however, resilience was not significantly associated with ART adherence. Among White individuals, there was no statistically significant association. The indirect effect between resilience and ART adherence through depressive symptoms was statistically significant (β = 0.041, p = 0.040) for Black individuals, while not statistically significant for White individuals (β = 0.024, p = 0.578). Interventions aimed at improving ART adherence, which attenuate depressive symptoms through accentuating resilience may be especially beneficial for Black populations living with HIV.
[Bushen Huatan recipe for treatment of polycystic ovary syndrome: therapeutic mechanism based on network pharmacology and molecular docking].

OBJECTIVE To explore the pharmacological mechanism of Bushen Huatan (BSHT) recipe in the treatment of polycystic ovary syndrome (PCOS). METHODS The active ingredients in the component drugs of the recipe were screened through TCMSP, and their potential targets were predicted by PubChem and Swiss target prediction. Genecards and OMIM were used to screen the therapeutic targets in the treatment of PCOS. The drug targets and disease targets were corrected using Uniprot, and the intersection targets were obtained. The protein-protein interaction (PPI) network was constructed using STRING, and the intersection targets were analyzed with CytoNCA to screen the core targets. DAVID was used for GO enrichment analysis and KEGG pathway enrichment analysis, and the core components and core targets were verified using AutoDock. Animal experiment was performed to verify the results using a female C57BL/6J mouse model of PCOS, treated daily with 1 mg/kg BSHT recipe granule for 35 days, and the ovarian expressions of the core targets and pathways were detected using Western blotting. RESULTS We identified a total of 125 potential active ingredients from the 14 component drugs in the recipe, 990 drug targets, 4759 PCOS targets and 434 intersection targets. The core active ingredients of the recipe included β -Sitosterol, kaempferol, and quercetin, whose core targets included PIK3CA, PIK3R1, APP, AKT1, and MAPK1. GO enrichment analysis highlighted such processes as drug reaction, negative regulation of apoptosis, and positive regulation of transcription from RNA polymerase Ⅱ promoter. The enriched KEGG pathways included primarily the cancer pathway and PI3K-Akt signaling pathway. Molecular docking showed that the core active ingredients had strong binding ability with the core targets. In the animal experiment, BSHT recipe was shown to improve the symptoms, down-regulate the expressions of PI3K and Akt proteins and up-regulate MAPK1 expression in the ovary of mice with PCOS. CONCLUSION The therapeutic mechanism of BSHT recipe for PCOS involves multiple active ingredients, multiple therapeutic targets and multiple pathways.
Association Between Muscle Mass Determined by D3‐Creatine Dilution and Incident Fractures in a Prospective Cohort Study of Older Men

The relation between a novel measure of total skeletal muscle mass (assessed by D3‐creatine dilution [D3Cr]) and incident fracture is unknown. In 1363 men (mean age 84.2 years), we determined D3Cr muscle mass; Fracture Risk Assessment Tool (FRAX) 10‐year probability of hip and major osteoporotic (hip, humerus, vertebral, forearm) fracture; and femoral neck bone mineral density (BMD) (by dual‐energy X‐ray absorptiometry [DXA]). Incident fractures were centrally adjudicated by review of radiology reports over 4.6 years. Correlations adjusted for weight and height were calculated between femoral neck BMD and D3Cr muscle mass. Across quartiles of D3Cr muscle mass/weight, proportional hazards models calculated hazard ratios (HRs) for any (n = 180); nonspine (n = 153); major osteoporotic fracture (n = 85); and hip fracture (n = 40) after adjustment for age, femoral neck BMD, recurrent fall history, and FRAX probability. Models were then adjusted to evaluate the mediating influence of physical performance (walking speed, chair stands, and grip strength). D3Cr muscle mass was weakly correlated with femoral BMD (r = 0.10, p < 0.001). Compared to men in the highest quartile, those in the lowest quartile of D3Cr muscle mass/weight had an increased risk of any clinical fracture (HR 1.8; 95% confidence interval [CI], 1.1–2.8); nonspine fracture (HR 1.8; 95% CI, 1.1–3.0), major osteoporotic fracture (HR 2.3; 95% CI, 1.2–4.6), and hip fracture (HR 5.9; 95% CI, 1.6–21.1). Results were attenuated after adjustment for physical performance, but associations remained borderline significant for hip and major osteoporotic fractures (p ≥ 0.05 to 0.10). Low D3Cr muscle mass/weight is associated with a markedly high risk of hip and potentially other fractures in older men; this association is partially mediated by physical performance. © 2022 American Society for Bone and Mineral Research (ASBMR).
Global Longitudinal Strain is Incremental to Left Ventricular Ejection Fraction for the Prediction of Outcome in Optimally Treated Dilated Cardiomyopathy Patients

Background Speckle tracking echocardiographic global longitudinal strain (GLS) predicts outcome in patients with new onset heart failure. Still, its incremental value on top of left ventricular ejection fraction (LVEF) in patients with nonischemic, nonvalvular dilated cardiomyopathy (DCM) after optimal heart failure treatment remains unknown. Methods and Results Patients with DCM were included at the outpatient clinics of 2 centers in the Netherlands and Italy. The prognostic value of 2‐dimensional speckle tracking echocardiographic global longitudinal strain was evaluated when being on optimal heart failure medication for at least 6 months. Outcome was defined as the combination of sudden or cardiac death, life‐threatening arrhythmias, and heart failure hospitalization. A total of 323 patients with DCM (66% men, age 55±14 years) were included. The mean LVEF was 42%±11% and mean GLS after optimal heart failure treatment was −15%±4%. Twenty percent (64/323) of all patients reached the primary outcome after optimal heart failure treatment (median follow‐up of 6[4–9] years). New York Heart Association class ≥3, LVEF, and GLS remained associated with the outcome in the multivariable‐adjusted model (New York Heart Association class: hazard ratio [HR], 3.43; 95% CI, 1.49–7.90, P=0.004; LVEF: HR, 2.13; 95% CI, 1.11–4.10, P=0.024; GLS: HR, 2.24; 95% CI, 1.18–4.29, P=0.015), whereas left ventricular end‐diastolic diameter index, left atrial volume index, and delta GLS were not. The addition of GLS to New York Heart Association class and LVEF improved the goodness of fit (log likelihood ratio test P<0.001) and discrimination (Harrell’s C 0.703). Conclusions Within this bicenter study, GLS emerged as an independent and incremental predictor of adverse outcome, which exceeded LVEF in patients with optimally treated DCM. This presses the need to routinely include GLS in the echocardiographic follow‐up of DCM.
Emotion regulation as a transdiagnostic factor in eating disorders and gambling disorder: Treatment outcome implications

Abstract Background A first approach addressed to ascertain whether emotion regulation (ER) could be a transdiagnostic construct between eating disorders (EDs) and gambling disorder (GD) (through a joint clinical clustering analysis of both disorders) was performed by Munguía et al. (2021). Both conditions were represented by a severe, moderate, and low ER profile subgroups, according to the degree of ER difficulties. Results showed a linear relationship between the severity of ER difficulties and the severity of the disorder and the psychopathological state. Aims Based on the aforementioned cross-sectional study, the objective of this longitudinal research was to explore the treatment response of the different ER subgroups. Methods 459 adult patients (n = 277 ED; n = 182 GD) were included. Several clinical variables, as well as outcome indicators (after completing 16 weeks of cognitive-behavioral therapy), were evaluated. Results The three subgroups found in the previous cross-sectional study were taken for the performance of the present research. ED and GD distribution in each subgroup replicates the one exposed by Munguía et al. (2021), as well as their characterization, considering psychopathology, disorder severity and personality traits. The low ER subgroup reported a better response to treatment, whereas the severe group had the highest rates of non-remission and dropouts. Conclusions Our results suggest that greater difficulties in ER lead to poorer treatment outcomes. Therefore, tailored treatments for patients with poor ER abilities would be recommended to improve adherence and treatment outcomes.
Sixteen weeks of aerobic exercise does not alter resting-state connectivity of the precuneus in patients with Alzheimer's disease.

INTRODUCTION In healthy elderly persons and patients with mild cognitive impairment, physical exercise can increase functional brain connectivity in the default mode network (DMN) measured by restingstate functional magnetic resonance imaging (rs-fMRI). However, no studies have so far investigated the effect of physical exercise on functional resting-state connectivity in the DMN in patients with Alzheimer's disease (AD). OBJECTIVE In a single-blinded randomized controlled trial, we assessed the effects of an aerobic exercise intervention of 16 weeks of physical exercise on DMN connectivity using rs-fMRI in patients with AD. METHODS Forty-five patients were randomly assigned to either a control or exercise group. The exercise group performed 60-min of aerobic exercise three times per week for 16 weeks. All the patients underwent whole-brain rs-fMRI at 3 T, at baseline, and after 16 weeks. Since the posterior cingulate cortex (PCC) and adjacent precuneus constitute a central hub of the DMN, this parietal region was defined as region-ofinterest and used as the seed region for functional connectivity analysis of the rs-fMRI data treating age and gender as covariates. RESULTS Neither seed-based analysis, seeded in the PCC/precuneus region nor ICA-based analyses, focusing on components of the DMN network, showed any exercise-induced changes in functional resting-state connectivity from baseline to follow-up. CONCLUSION 16 weeks of aerobic exercise does not modify functional connectivity of the PCC/precuneus region in patients with AD. A longer intervention may be needed to show the effect of exercise on brain connectivity.