Miracle-dz/UniFAR-FTUs huggingface dataset:
Analysis of hospital and payer costs of care: aggressive warming versus routine warming in abdominal major surgery

Background Hypothermia is common and active warming is recommended in major surgery. The potential effect on hospitals and payer costs of aggressive warming to a core temperature target of 37°C is poorly understood. Methods In this sub-analysis of the PROTECT trial (clinicaltrials.gov, NCT03111875), we included patients who underwent radical procedures of colorectal cancer and were randomly assigned to aggressive warming or routine warming. Perioperative outcomes, operation room (OR) scheduling process, internal cost accounting data from the China Statistical yearbook (2022), and price lists of medical and health institutions in Beijing were examined. A discrete event simulation (DES) model was established to compare OR efficiency using aggressive warming or routine warming in 3 months. We report base-case net costs and sensitivity analyses of intraoperative aggressive warming compared with routine warming. Costs were calculated in 2022 using US dollars (USD). Results Data from 309 patients were analyzed. The aggressive warming group comprised 161 patients and the routine warming group comprised 148 patients. Compared to routine warming, there were no differences in the incidence of postoperative complications and total hospitalization costs of patients with aggressive warming. The potential benefit of aggressive warming was in the reduced extubation time (7.96 ± 4.33 min vs. 10.33 ± 5.87 min, p < 0.001), lower incidence of prolonged extubation (5.6% vs. 13.9%, p = 0.017), and decreased staff costs. In the DES model, there is no add-on or cancelation of operations performed within 3 months. The net hospital costs related to aggressive warming were higher than those related to routine warming in one operation (138.11 USD vs. 72.34 USD). Aggressive warming will have an economic benefit when the OR staff cost is higher than 2.37 USD/min/person, or the cost of disposable forced-air warming (FAW) is less than 12.88 USD/piece. Conclusion Despite improving OR efficiency, the economic benefits of aggressive warming are influenced by staff costs and the cost of FAW, which vary from different regions and countries. Clinical trial registration clinicaltrials.gov, identifier (NCT03111875).
Polyphenol Extraction from Food (by) Products by Pulsed Electric Field: A Review

Nowadays, more and more researchers engage in studies regarding the extraction of bioactive compounds from natural sources. To this end, plenty of studies have been published on this topic, with the interest in the field growing exponentially. One major aim of such studies is to maximize the extraction yield and, simultaneously, to use procedures that adhere to the principles of green chemistry, as much as possible. It was not until recently that pulsed electric field (PEF) technology has been put to good use to achieve this goal. This new technique exhibits many advantages, compared to other techniques, and they have successfully been reaped for the production of extracts with enhanced concentrations in bioactive compounds. In this advancing field of research, a good understanding of the existing literature is mandatory to develop more advanced concepts in the future. The aim of this review is to provide a thorough discussion of the most important applications of PEF for the enhancement of polyphenols extraction from fresh food products and by-products, as well as to discuss the current limitations and the prospects of the field.
Determination of Anthocyanin Content of Purple Sweet Potato (Ipomea batatas L) Extract Using the Differential pH Method

Purple sweet potato (Ipomea batatas L) is a type of tuber that has many benefits in the food and health . he purple color in sweet potatoes is caused by the presence of anthocyanin purple pigments that spread from the skin to the tuber flesh. The content of sweet potato anthocyanins depends on the intensity of the color of the tubers. The purple the color of the tubers, the higher the anthocyanin content. Anthocyanins have various health benefits, namely as antioxidants, anti diabetic and other benefits, namely as natural dyes.This study aims to determine the levels of anthocyanins in purple sweet potato extract by using Differential pH method. From the research results, it can be concluded that the anthocyanin content of purple sweet potato (Ipomea Batatas L) is 4.26 mg/liter.
Extracting Mineralization Information by Hyperspectral Analysis Based on Rough Set Theory

The wall rock alteration is important for information hydrothermal deposits prospecting,and so the effective extraction of mineralization information has aroused great interests among geologists in remote sensing geology.In this experiment,the data collected from field surveys and spectral measurements were analysed based on rough set theory.The decision table is established for mineralization information identification by taking the 16 spectral characteristics as condition attribute set and taking degree of rock alteration as decision attribute set and discretization data.By reducing decision table to cut off redundant condition attribute,the rules between mineralization information and spectral curve features were extracted.At last,the rules were tested by the other data of mining area.The result is basically consistent with field surveys data.This shows that the method can be used as model Hyperspectral mineralization information identification,and can provide evidence for metallogenic prognosis.
Cell-free DNA measurement of three genomes after allogeneic MSC therapy in kidney transplant recipients indicates early cell death of infused MSC

Introduction Mesenchymal stromal cell (MSC) therapy is a promising treatment that allows for drug minimization in clinical kidney transplantation. While it is thought that MSCs rapidly go into apoptosis after infusion, clinical evidence for this is scarce since methods to detect cell death of infused cells in vivo are lacking. Cell-free DNA (cfDNA) has recently gained attention as a biomarker for cell death. Methods In this study, we longitudinally measured cfDNA in plasma samples of the recipient, kidney donor, and allogeneic third-party MSC in the context of the Neptune study. cfDNA levels were measured at several time points before and after allogeneic MSC infusion in the 10 recipients who participated in the Neptune study. cfDNA ratios between the recipient, kidney graft, and MSC were determined. Results We observed a peak in MSC-derived cfDNA 4 h after the first and second infusions, after which MSC-derived cfDNA became undetectable. Generally, kidney graft-derived cfDNA remained in the baseline-level range. Discussion Our results support preclinical data that MSC are short-lived after infusion, also in a clinical in vivo setting, and are relevant for further research into the mechanism of action of MSC therapy.
Shallow-Water Broadband OBS Seismology

Abstract The recent development of broadband ocean-bottom seismometers that can be deployed for more than a year has led to the construction of large ocean-bottom seismometer (OBS) fleets and to many successful experiments studying Earth structure and tectonics beneath the oceans. However, ocean surface waves raise noise levels at deep ocean-floor sites far above those at continental sites in the microseism band between 0.2 and 10 sec period, and currents and ocean waves raise noise levels at longer periods. Broadband OBSs are rarely deployed in shallow water because of a fear of loss due to bottom trawling and an expectation of very high noise levels from strong currents and the nearby ocean surface. However, these noise sources can be overcome such that shallow OBS deployments may provide noise levels that are comparable to deep-water sites at periods >10 sec and lower than deep-water sites at shorter periods. Burial of the instrument into the sediments can shield the seismometer from current noise, while the noise from deformation under wave loading can be removed using pressure gauge data. We predict the noise levels can be reduced to allow the detection of Rayleigh waves from 20 to 200 sec period with good signal-to-noise ratio (SNR) from teleseismic earthquakes as small as M w 5. Short-period ( M w 4.5.
Tissue specificity of fMRI signals at Ultra-high resolution - but where in the tissue?

a reduced FOV along the phase encode direction was applied using a selective refocusing pulse. This allowed us to reduce the number of segments needed for the high resolution images. Imaging parameters: FOV: 3.84 x 0.96 cm2 (matrix 256 x 64); Voxel size: 0.15 x 0.15 x 2 mm 3 ; 2 segments. TE/TR =40ms/4s. Activation maps were overlaid on corresponding anatomical images. The MR signals were cross-correlated with the stimulation paradigm to identify active pixels. Histology: Following the MR session, the animals were transcardially perfused with 0.1M phosphate buffered saline, followed by a 4% paraformaldhyde (PA) in 0.1M phosphate buffer. The brain was removed and was postfixed in 4% PA. Digital photographs were taken of the intact fixed brain. A 3mm cortical slab (see below) was extracted. The cortical slab was then sectioned with a 15µm slice thickness with a cryostat and was stained with cresyl violet for identification of neuronal distribution. The border between layers was determined based on cytoarchitectonic criteria such as cell types, size and density. Co-registration: The co-registration of the MR images with the histology preparation was achieved by a multi stage aligning process. Initially, the high quality TurboFlash image corresponding to the functional slice was aligned with a coronal slice of the 3-D GEMS image using BrainVoyager (Brain Innovation, Netherlands). Then, by only adjusting the Z-coordinates, a dorsal (TRA) view was obtained while keeping the coronal functional image plane location market. The TRA image with the market functional slice was then aligned with a photographed dorsal view of the intact brain using visible landmarks (Adobe, Photoshop). Once the exact image plane was determined, a 3mm slab was sectioned and the block underwent histological preparation. Results Activation maps were superimposed on high-resolution anatomical images in which the gray and white matter borders were outlined. Panels a-c show GE-BOLD, HSE-BOLD and GE-MION activation maps, respectively. Activation was confined to the primary visual areas (corresponding to Brodmann’s areas 17 & 18) and closely followed the gray matter contour. The highest GE-BOLD signal changes were observed at the cortical surface coincides with the large surface vessels. However, in all three maps, spatially defined signal changes were centered over the gray matter region. Following the imaging session, the brain was removed, and the imaged slice was identified (d–e). The cortical slab corresponding to the image plane underwent histological staining (f) and the borders of the cortical layers were identified. The tissue signals were mainly arose from the lower portion of cortical layers II/III and extended down to layer V. Discussion
Magnetic storm associated perturbations of the upper atmosphere: Recent results obtained by satellite‐borne gas analyzers

This review summarizes some of the recent results on the disturbed upper atmosphere obtained by satellite-borne gas analyzers. According to these measurements, magnetospheric activity leads to the development of two different disturbance zones. The high- and middle-latitude region is characterized by an increase in the heavier constituents Ar, N2, and O2, by a height-dependent behavior of O, and by a significant decrease of He. The reaction time of the atmosphere is much smaller than one orbital period. At lower latitudes a moderate increase of all constituents is observed. A comparison between atmospheric and ionospheric data demonstrates that, in contrast to positive effects, negative ionospheric storms are closely coupled to changes in the neutral composition. In addition, model calculations fully support a causal relation between both phenomena. Given this correlation, atmospheric and negative ionospheric disturbance effects have certain variations in common. These include systematic changes with the magnetic storm intensity, with magnetic position, with local time, and with season. Whereas the presently available empirical and theoretical models are quite capable of reproducing the basic properties of the observed atmospheric perturbations, these algorithms are not sophisticated enough for a more detailed description of the data.
An Institutional Perspective on Strategic Alignment of International Human Resource Management in Multinational Enterprises

ABSTRACT Multinational enterprises (MNEs) seek global alignment of international human resource management (IHRM) systems and practices for efficiency and control. Previous studies have provided conflicting evidence regarding the best approach for HR implementation across countries. Disparate institutional contexts in host countries may make MNE strategic IHRM alignment problematic. Adopting an institutional perspective, we offer a conceptual model which addresses these obstacles through the provision of a process approach solution. We extend the general MNE model to emerging market multinationals (EMNEs), highlighting why EMNEs differ from traditional MNEs in seeking SIHRM alignment. Implications for practice and future research are discussed.
IDENTIFICATION OF POTENTIAL STUDY OF CULTURAL HERITAGE ON CHINESE COIN FINDINGS IN BANYUWANGI DISTRICT

Many Chinese coins are found in Banyuwangi district with various variations. The purpose of this study was to identify the findings of Chinese coins in Setembel hamlet, Gambiran village, Banyuwangi district. The formulation of the problem is how to identify findings of Chinese coins? , and what is the history of dynasties in Chinese coins in Banyuwangi. The method used is a qualitative method using the Magnifying Plus Application, the Pleco Android Application and Chinese Handwriting Recognizing. Research results Identification Results Of the 76 samples of Chinese coins that can be identified and classified based on the ruling dynasty and kings in China, 52 pieces were identified, 24 pieces were illegible due to wear and tear. Based on the above classification, the most commonly found in Banyuwangi are Chinese products from the Song dynasty, 80% and 20% from the Ming dynasty.
Construction of heat stress regulation networks based on Illumina and SMRT sequencing data in potato

Potato (Solanum tuberosum L.) is one of the most important tuber food crops in the world; however, the cultivated potatoes are susceptible to high temperature, by which potato production is adversely affected. Understanding the coping mechanism of potato to heat stress is essential to secure yield and expand adaptability under environmental conditions with rising temperature. However, the lack of heat-related information has significantly limited the identification and application of core genes. To gain deeper insights into heat tolerance genes, next-generation sequencing and single-molecule real-time sequencing were used to learn the transcriptional response of potato to heat stress and 13,159 differentially expressed genes (DEGs) were identified in this study. All DEGs were grouped into 12 clusters using the K-means clustering algorithm. Gene Ontology enrichment analysis revealed that they were involved in temperature signaling, phytohormone, and protein modification. Among them, there were 950 differentially expressed transcription factors (DETFs). According to the network analysis of DETFs at the sixth hour under heat stress, we found some genes that were previously reported to be associated with photoperiodic tuberization, StCO (CONSTANS), tuber formation, StBEL11 (BEL1-LIKE 11), and earliness in potato, StCDF1 (CYCLING DOF FACTOR 1) responding to temperature. Furthermore, we verified the relative expression levels using quantitative real-time polymerase chain reaction, and the results were consistent with the inferences from transcriptomes. In addition, there were 22,125 alternative splicing events and 2,048 long non-coding RNAs. The database and network established in this study will extend our understanding of potato response to heat stress. It ultimately provided valuable resources for molecular analysis of heat stress response in potato and cultivation of potato varieties with heat tolerance.
Predicting life expectancy of lung cancer patients after thoracic surgery using SMOTE and machine learning approaches

Lung cancer is a life-threatening condition characterized by the uncontrolled growth and spread of abnormal cells in the lungs. Thoracic surgery is a commonly employed diagnostic and treatment procedure for lung cancer. The objective of this study is to utilize machine learning techniques to predict the life expectancy of lung cancer patients one year after thoraric surgery. The study utilizes the Thoraric Surgery Data Set, consisting of 454 data, with 385 data representing surviving patients and 69 data representing patients who passed away. Due to an imbalance in the data, the Synthetic Minority Oversampling Technique (SMOTE) process is applied to balance the dataset. Multiple machine learning algorithms, including Random Forest (RF), K-Nearest Neighbor (KNN), and Support Vector Machine (SVM), are employed for prediction. Validation is performed using 5-fold cross validation, repeated three times. The results indicate that the KNN model achieves the highest mean accuracy of 84.80% before the SMOTE process, although all models exhibit a low mean F1-score. Following the SMOTE process, the RF model attains the highest mean accuracy of 79.52%, while the KNN model demonstrates the highest mean F1-score of 26.54%. This research contributes valuable insights to clinicians in making informed decisions and improving patient outcomes.
Analysis on Spatial Distribution of Cumulonimbus and Its Circulation Characteristics over the Qilian Mountains

The cloud data observed by 29 meteorological stations in the Qilian Mountains during the period of 1961-2001 are used to analyze the spatiotemporal characteristics of cumulonimbus and the relationship between it and atmospheric circulation change in recent 41 years.The results are as follows:(1) Frequency of cumulonimbus over the main areas of the Qilian Mountains was higher than that over the peripheral regions because of the terrain power lifting effect.The highest frequency of cumulonimbus occurred in summer(25%～43%),and then followed by that in spring(16%～27%),autumn(10%～19%) and winter(10%). (2) Cumulonimbus was in an increase trend over the Qaidam Basin but a decrease trend over other regions. (3) Annual variation of cumulonimbus over the Qilian Mountains can be roughly divided into four stages:cumulonimbus increased obviously during the period of 1961-1967,decreased sharply during the period of 1968-1970,increased slowly during the period of 1971-1988,and decreased obviously during the period of 1989-2001. (4) Precipitation in spring is closely related to the frequency of cumulonimbus. (5) The highest difference of cumulonimbus between the years with the most and least cumulonimbus occurred in July and May,and the difference between the years with the most and least cumulonimbus at 500 hPa was obvious. (6) The circulation characteristic indexes closely related to the frequency of cumulonimbus were mainly the subtropical high north boundary,the ridge line,the zonal circulation,the polar vortex intensity and the Qinghai-Tibetan Plateau height field index. (7) A forecast model of the frequency of cumulonimbus over the Qilian Mountains is developed.
Discovering the fish fauna of a lagoon from the southeast of the Yucatan Peninsula, Mexico, using DNA barcodes

Background Aquatic ecosystems in the tropics are typically environments with a high species richness of fishes. These systems are also among the most vulnerable in the world, threatening the overall biodiversity of tropical regions. As a first step, it is important to enumerate the species in any ecosystem to promote its conservation. This study aims to inventory the ichthyofauna in the Chile Verde Lagoon, Quintana Roo, on the Yucatan Peninsula, a system fortunately well protected in Mexico, based on faunal surveys backed up with mtDNA barcodes. Methods We collected larvae, juveniles, and adults of fishes in the lagoon with a variety of sampling gear targeting various life stages. Species were identified using both morphology and DNA barcodes. The abundance of species and ichthyoplankton biomass (wet weight, suction technique) were calculated from 43 samples. Results We collected 197 adult and juvenile fishes and 3,722 larvae, of which 306 specimens were DNA-sequenced with a success rate of 96.7%. We identified 13 families, 24 genera, and 27 species in our inventory. The species number was estimated to comprise 75% of the potential total richness using the Chao 1 richness estimator. Clupeids and gobiids accounted for 87.9% of the total abundance of fishes, and, together with cyprinodontids, also accounted for the highest ichthyoplankton biomass. Conclusion Adult and juvenile fishes were identified by morphology and meristic values, however larvae required DNA barcoding to identify species. The high biomass and abundance of larvae of clupeids, gobiids and cyprinodontids suggests that the Chile Verde Lagoon may be important for reproduction of these species in the region. Microgobius microlepis, a marine goby species, is reported for the first time in an inland oligohaline system. This study provides a basis for future environmental assessment and biomonitoring of the Chile Verde Lagoon in the Yucatan Peninsula of Mexico.
Research on the Application of Knowledge Graph in Academic Resource Discovery Service

[Objective] To apply user graph to the service process of academic resource discovery, alleviate the dilemma of knowledge loss, and provide reference for the construction and application of user graph in university libraries. [Process] Taking academic resource discovery service as the application scenario, this paper analyzes the source, structure and characteristics of university library user data, and defines the user graph construction process of "knowledge extraction - knowledge fusion - knowledge snapshot - graph tailoring". The project of embedding user graph into academic resource discovery service process was discussed in three stages: before, during and after, and user behavior data was used for analysis and testing. [Results] The experiment proved that user graph can optimize the input and output of academic resource discovery service, reduce the cost of user behavior, and provide a reference for the application of knowledge graph.
Impact of Slot Width on Performance of Symmetrical-Slot-Antenna Resonant-Tunneling-Diode Oscillators

In this article, we show that the output power of symmetrical-slot-antenna resonant-tunneling-diode (RTD) oscillators depends on the slot width. The dependence could be used as a fine-tuning degree of freedom to increase the output power of the oscillators. The fine-tuning mechanism is related to maximizing the RTD-oscillation amplitude by a proper balance between the slot-antenna radiation and ohmic losses, and the slot susceptance. The presented simulation results are in agreement with the experimental data in the frequency range of 150–400 GHz. We report the output powers of 283 <inline-formula><tex-math notation="LaTeX">$\mu$</tex-math></inline-formula>W at 184 GHz and 82 <inline-formula><tex-math notation="LaTeX">$\mu$</tex-math></inline-formula>W at 368 GHz, which are very close to the state-of-the-art literature data for the given type of RTD oscillators.