Miracle-dz/UniFAR-FTUs huggingface dataset:
MeMAD Deliverable D 2 . 3 Software and demonstration of human-like content description generation

This deliverable describes the last development iteration of the joint collection of libraries and tools for multimodal content analysis and description from AALTO, EURECOM, INA, Lingsoft, LLS and Limecraft. The methods generate unimodal descriptions of video contents in the aural and visual domains. These descriptions can be used as such and also combined to describe the contents in a multimodal fashion as enriched video captions. The ultimate goal of the development is to be able to generate human-like content descriptions, in which the persons, objects, actions and environments, both seen and heard, are described in a sophisticated way. In this deliverable, a number of improvements we have made in that direction are elaborated. We describe a small-scale dataset used in the experiments and demonstrate and evaluate various multimodal combinations of the unimodal inputs with that data. As part of this deliverable, the existing open source components gathered into a joint software collection of tools and libraries have been updated and new components have been added. Finally, the abstracts of academic theses together with full texts of scientific publications appear at the end of the report. MeMAD – Methods for Managing Audiovisual Data Deliverable 2.3 2
The Hepatologist in the Haematologist Field: A Rare Cause of Non-Cirrhotic Portal Hypertension

An 81 year-old gentleman was admitted to the emergency department of our hospital due to hematemesis and melena, and endoscopic evidence of portal hypertension. Due to presence of ascites and esophageal varices he was referred to gastroenterology care. His history included systemic mastocytosis, and biochemistry showed marked cholestasis with normal liver function tests. Clinical work-up was not consistent with liver disease-related portal hypertension, but rather hepatic involvement of systemic mastocytosis and the development of non-cirrhotic portal hypertension. This clinical case highlights that although systemic mastocytosis is uncommon, the subsequent development of liver involvement and non-cirrhotic portal hypertension are complications of the disease that need always be considered.
Rationale and Design of a Multicenter Echocardiographic Study to Assess the Relationship between Cardiac Structure and Function and Heart Failure Risk in a Biracial Cohort of Community Dwelling Elderly Persons: The Atherosclerosis Risk in Communities (ARIC) Study

Background— Heart failure (HF) is an important public health concern particularly among persons over 65 years of age. Women and African Americans are critically understudied populations that carry a sizeable portion of the HF burden. Limited normative and prognostic data exist regarding measures of cardiac structure, diastolic function, and novel measures of systolic deformation in older adults living in the community. Methods and Results— The Atherosclerosis Risk in Communities (ARIC) study is a large, predominantly biracial NHLBI-sponsored epidemiologic cohort study. Between 2011 and 2013, approximately 6,000 surviving participants, expected to return for a 5 th study visit during which comprehensive 2D, Doppler, tissue Doppler, and speckle-tracking echocardiography will be performed uniformly in all cohort clinic visit participants. The following objectives will be addressed: (1) to characterize cardiac structural and functional abnormalities among the elderly and determine how these differ by gender and race/ ethnicity, (2) determine the relationship between ventricular and vascular abnormalities, and (3) prospectively examine the extent to which these non-invasive measures associate with incident HF. Conclusions— We describe the design, imaging acquisition and analysis methods, and quality assurance metrics for echocardiography in Visit 5 of the ARIC cohort. A better understanding of the differences in cardiac structure and function through the spectrum of HF stages in the elderly generally, and between genders and racial/ethnic groups specifically, will deepen our understanding of the pathophysiology driving HF progression in these at-risk populations and may inform novel prevention or therapeutic strategies. in the community setting and determine how these associations vary by gender and race/ethnicity. The study will investigate ventricular-arterial coupling in addition to the association of cardiac structure and function with arterial stiffness assessed by contemporaneous carotid-femoral pulse wave velocity, aortic morphology, and ankle-brachial index. The third aim is to prospectively examine the extent to which these non-invasive measures associate with incident HF and determine the degree to which these associations vary by gender and race/ethnicity. This study will assess the incremental value of LV deformation, pulmonary pressure and vascular resistance, and RV function in predicting risk of HF beyond LV structure and conventional measures of systolic and diastolic function. In accomplishing these objectives, this study is developing an echo imaging database that will facilitate future investigations to: 1) compare these echo measures both to studies previously performed in the ARIC Jackson cohort (1993–1995) and to studies in complementary cohorts; and 2) evaluate novel strain-based and 3D measures of cardiac function, including the LA and RV.
Computational Determination of Reactivity Descriptors, Vibrational Analysis and Nuclear Magnetic Resonance of

The title compound, pyrazole carbaldehyde have been optimized using Gaussian 9 software program, via density functional theory framework (DFT/B3LYP) by 6-311G (d, p) basis set, the output file was visualize using Gaussian view program, geometric properties, thermochemical and reactivity descriptors such as ionization potential (IP), electron affinity (EA), electronegativity (χ), chemical potential (μ), hardness (η), softness (σ), electrophilicity index (ω) and nucleophilicity index (N) were calculated. Mapping of electrostatic surface potential (MESP) allow us to establish trends that enable making predictions about the reactive sites of the studied compound. Besides, the optimized structure is subjected to frequency analysis at the same level of theory to obtain thermodynamic correction values. Vibrational assignments and nuclear magnetic resonance ( 1 H- & 13 C-NMR) chemical shifts of the molecule were calculated by gauge independent atomic orbital (GIAO) method using the CPCM model, and mapping of current density shielding of proton and carbon nucleus of the aldehyde group shied light on the molecular properties and reactivity of 5-oxo-1-phenyl-4-(2-phenylhydrazono)-4,5- dihydro-1H-pyrazole-3-carbaldehyde structure-properties relationships. Reactivity parameters calculated from the frontier orbitals help in prediction of chemical potential, hardness, softness, electrophilicity as well as nucleophilicity of the pyrazol-carbaldehyde molecule. Moreover, thermodynamic parameters verify the conclusions drawn from the molecular polarity. Computed and visualized MESP map surfaces enable exploration of molecular reactive sites (hydrazone moiety and the aldehyde group), which confirmed by mapping of shielding density by nuclei H-31, C-31, H-34 in the XX direction mapped on the current density.
Fusion de données ; ultime étape de reconnaissance de formes : application à l'identification et à l'authentification

Data fusion is a discipline with many strong points and difficulties of all kinds. Various methods are developped but none of them is satisfactory for all kinds of information. Two comparative studies for personnal identificaton and authentication through their hand geometry and handwritten signatures are presented. In our methodology several classifiers based on various feature sets are initially created and then fusionned. We are proposing a fuzzy formalism to define various membership degrees of an unknown pattern to different classes based on the distance information. The three parameters optimization enhancees the robustness of k-NN rule. It is also used to define the evidence masses and the possibility distributions. Lastly, it is used to combine classifiers with creation of a meta-classifier. Another developped approach, evidence theory is also employed for an edge detection problem on a pixel level fusion. The applications show the generic character of our work.
Opening the Science Gateway: Lessons from the Materials Project Workshop

—The Materials Project (MP) has served as an effec- tive dissemination platform for computational materials science data for nearly 8 years. In its capacity as a Science Gateway, it serves about 60,000 users from around the world with data on over 80,000 crystalline materials. In recent years, MP’s growing popularity has been facilitated by educational resources developed by its core team and diligently maintained documentation of the methodology and provenance associated with its data. In this report, we highlight a recent effort by MP to standardize a set of educational materials for its user base in its annual Materials Project Workshop , which was conducted in the summers of 2016 and 2017 and will be hosted again in August, 2018. More speciﬁcally, we describe our insights on how organization of material, presentation format, formative assessment, and active learning were integrated to produce an effective educational experience for our attendees. We also highlight the lessons we have learned, in the hopes other Science Gateway efforts may draw on our experiences in crafting their own educational and training resources.
0 31 20 11 v 1 2 D ec 2 00 3 Quantum electrodynamics of relativistic bound states with cutoffs

We consider an Hamiltonian with ultraviolet and infrared cutoffs, describing the interaction of relativistic electrons and positrons in the Coulomb potential with photons in Coulomb gauge. The interaction includes both interaction of the current density with transversal photons and the Coulomb interaction of charge density with itself. We prove that the Hamiltonian is self-adjoint and has a ground state for sufficiently small coupling constants. E-mail: barbarou@cpt.univ-mrs.fr E-mail: dimassi@math.univ-paris13.fr E-mail: guillot@cmapx.polytechnique. fr 1
Comparative evaluation of the Vitek 2 yeast susceptibility test and CLSI 1 broth microdilution reference method for antifungal susceptibility testing 2 of invasive yeast isolates in Italy: the GISIA3 study

20 Objectives: The newly available AST-YS01 Vitek 2 cards were evaluated and compared with 21 the CLSI M27-A2 microdilution reference method. 22 Methods: Clinical yeast isolates, including 614 Candida spp. , 10 Cryptococcus neoformans , 23 1 Geotrichum capitatum and 2 quality control strains, were tested for susceptibility to 24 amphotericin B, fluconazole and voriconazole using both methods. 25 Results: The majority of yeast isolates were susceptible to all antifungal agents tested: MIC 90 26 values as determined by Vitek 2 and CLSI methods were, respectively, 0.5 and 1 µ g/ml for 27 amphotericin B, 8 and 16 µ g/ml for fluconazole and <0.12 and 0.25 µ g/ml for voriconazole. 28 Overall there was excellent categorical agreement (CA) between the methods (99.5% for 29 amphotericin B, 92% for fluconazole, 98.2% for voriconazole), but discrepancies were 30 observed within species. Fluconazole CA was low for Candida glabrata and Candida krusei 31 when CLSI 48 h results were considered. Moreover, the fully automated commercial system 32 did not detect susceptibility of Cryptococcus neoformans to voriconazole. 33 Conclusions: The Vitek 2 system can be considered a valid support for antifungal 34 susceptibility testing of yeasts, but susceptibility testing to agents not included in the system 35 (e.g. echinocandins and posaconazole) should be performed with other methods.
ACCESSORY PLASMA FACTORS INVOLVED IN THE BACTERICIDAL TEST FOR TYPE-SPECIFIC ANTIBODY TO GROUP A STREPTOCOCCI

Human bloods have been shown to vary in the efficiency with which they. 0Psonize Group A streptococci in the presence of constant amounts of antibody to homologous type M protein (1, 2). This variation has been found to be due to either qualitative or quantitative differences in the accessory plasma factors that enhance phagocytosis of antibody-coated organisms. The hyaluronic acid capsule of the Group A streptococcus has been implicated as an important factor in its resistance to phagocytosis (3--6). Recently, Hirsch and Church (7) have postulated that a "capsule-neutralizing" thermolabfle factor in human plasma is required for the efficient phagocytosis of encapsulated strains. This study will present evidence to support the concept that the capsule of the Group A streptococcus imposes an opsonic requirement for a thermolabile plasma factor(s) which is present in varying amounts in human bloods and which appears to be independent of the complement system. On the assumption that this is a plasma cofactor which further enhances the rate of phagocytosis of encapsulated organisms in the presence of antibody to M protein and possibly complement components, it will be referred to hereafter as streptococcal C~coopsonirl. ~'
On the complexity of a concentrator

In this paper a swi tcbing network with n inputs and m outputs is considered. The network satisfies the following condition: any k ~ m inputs can be simultaneously connected to some k outputs. Such networks are r eferred to as (n, m) concentrators. The problem of constructing a concentrator with a mini mum possible number of crosspoints is investigated. A c oncentrator with less t han 29n c IQ sspoints is constructed. Two cases are considered: a) ~-O for noO , b) ~-1 for n--OG • n n The constructed concentrator has asymptotically no more than 3n c rosspoints in the case (a) and 4n c rosspoints in the case (b). 318/1 The paper is concerned with a switching network having n inputs and m outputs (m <n) and satisfying the following condition: any k ~ m inputs can be simultaneously connected to some k outputs. Such networks are referred to as (n, m) concentrators. The paper deals with the problem of constructing concentrators with a minimum possible number of c rosspoint s. As in [1J, the problem is formulated and solved in terms of the theory of graphs. It is necessary to construct an oriented n puts graph f in which any m inputs of n m outinputs can be connected to m outputs by non-intersecting paths. The number Q(f) of crosspoints of a concentrator is determined as the number of edges in this graph f. Let Fn,m be a set of all ~riented graphs f which are (n, m) concentrators and Q(n, m) = min Q(f) fE Fn,m (1 ) The main results of the work can be summarized in the following theorem. Theorem: (a) 2n-2 ~ Q(n, m) < cn, m~2 (2) where the constant c <29 is independent of n and m; (b) Q(n, an) ~3n(1+o(1) ), 0(1 )-0 forv<. -~ 0, n --. :. 00 (c) Q (n,o(n)~4n(1+0(1) ), 0(1)--0 fora---1, n00 (3) it)
Experimental Based Learning and Modeling of Computer Networks

Computer network experts are in great demand these days. This study aims to examine the effectiveness of using Cisco Packet Tracer as a simulation tool. This development reflected significant importance for higher education institutions. It ensures that all students have ample networking assistances. The computer network needs consideration of theory and practice. Hence, Cisco packet tracer software is recommended to solve this difficulty. In this paper, design and simulation of a computer network with Cisco network packet tracer simulation software is illustrated. This software would normally not work deprived of a variety of configurations. So, essential steps and configurations of software are explained in this paper which is useful in network design. Extensive simulation results validate this model.
A Subjective Optimal Strategy for Transit Simulation Models

A behavioural modelling framework with a dynamic travel strategy path choice approach is presented for unreliable multiservice transit networks. The modelling framework is especially suitable for dynamic run-oriented simulation models that use subjective strategy-based path choice models. After an analysis of the travel strategy approach in unreliable transit networks with the related hyperpaths, the search for the optimal strategy as a Markov decision problem solution is considered. The new modelling framework is then presented and applied to a real network. The paper concludes with an overview of the benefits of the new behavioural framework and outlines scope for further research.
The impact of moving to a 12 hour shift pattern on employee wellbeing: a qualitative study in an acute mental health setting

Background: Against a backdrop of increasing demand for mental health services, and difficulties in recruitment and retention of mental health staff, employers may consider implementation of 12-hour shifts to reduce wage costs. Mixed evidence regarding the impact of 12-hour shifts may arise because research is conducted in divergent contexts. Much existing research is cross sectional in design and evaluates impact during the honeymoon phase of implementation. Previous research has not examined the impact of 12-hour shifts in mental health service settings. Objective: To evaluate how employees in acute mental health settings adapt and respond to a new 12-hour shift system from a wellbeing perspective. Design: A qualitative approach was adopted to enable analysis of subjective employee experiences of changes to organisation contextual features arising from the shift pattern change, and to explore how this shapes wellbeing. Setting(s): Six acute mental health wards in the same geographical area of a large mental health care provider within the National Health Service in England. Participants: 70 participants including modern matrons, ward managers, clinical leads, staff nurses and healthcare assistants. Methods: Semi-structured interviews with 35 participants at 6 months post-implementation of a new 12-hour shift pattern, with a further 35 interviewed at 12 months post-implementation. Results: Thematic analysis identified unintended consequences of 12-hour shifts as these patterns changed roles and the delivery of care, diminishing perceptions of quality of patient care, opportunities for social support, with reports of pacing work to preserve emotional and physical stamina. These features were moderated by older age, commitment to the public healthcare sector, and fit Conclusions: Findings indicate potential exists for differential wellbeing outcomes of a 12-hour shift pattern and negative effects are exacerbated in a stressful and dynamic acute mental health ward context. In a tight labour market with an ageing workforce, employee flexibility and choice are key to retention and wellbeing. Compulsory 12-hour shift patterns should be avoided in this setting.
Power Electronics for Wireless Power Delivery in Synthetic Sensor Networks

Energy harvesting is a very popular means of augmenting batteries or displacing their use for powering the wireless sensor networks; however, an alternative approach is to use wireless power delivery to energise the nodes. For a network occupying a well-known and confined physical geometry, it may be possible to achieve this via one or multiple sources in fixed locations; however, when the nodes cover a wide area, or are themselves mobile, fixed sources may not be practical. A possible solution is to use drones which can fly close to the sensor nodes, which then transfer power inductively from drone to node. In such systems the drone could also be used to gather data from the sensors nodes, reducing their power requirement for long distance data transmission. However, here we investigate the power electronics and energy storage solutions for this so-called synthetic sensor network (synthsense) setup. Here we describe the preliminary hardware subsystems which will allow the demonstration of synthsense.
Differentiation to Macrophages Hematopoietic Progenitor Cells and CD137 Induces Proliferation of Murine

2 CD137 is a member of the TNFR family, and reverse signaling through the CD137 ligand, which is expressed as a cell surface transmembrane protein, costimulates or activates APCs. CD137 and CD137 ligand are expressed on small subsets of bone marrow cells. Activation of bone marrow cells through CD137 ligand induces proliferation, colony formation and an increase in cell numbers. Compared with total bone marrow cells, the small subpopulation of progenitor cells that express no lineage markers but express CD117 cells (or Lin (cid:1) , CD117 (cid:2) cells) responds with the same activities to CD137 ligand signaling, but at a signiﬁcantly enhanced rate. Concomitantly to proliferation, the cells differentiate to CFU granulocyte-macrophage and CFU macrophage, and then to monocytes and macrophages but not to granulocytes or dendritic cells. Hematopoietic progenitor cells differentiated in the presence of CD137 protein display enhanced phagocytic activity, secrete high levels of IL-10 but little IL-12 in response to LPS, and are incapable of stimulating T cell proliferation. These data demonstrate that reverse CD137 ligand signaling takes place in hematopoietic progenitor cells, in which it induces proliferation, an increase in cell numbers, colony formation, and differentiation toward monocytes and macrophages. The Journal of Immunology, 2008, 181: 3923–3932.
A 0.02% THD and 80 dB PSRR filterless class D amplifier with direct lithium battery hookup in mobile application

This paper presents a fully integrated CMOS filterless class D amplifier that can directly hook up lithium battery in mobile application The proposed amplifier embodies a 2-order feedback path architecture instead of direct feedback of output to input of the integrator to decrease the high frequency intermodulation distortion associated with direct feedback and eliminate the integrator input common mode disturbance from the output in ternary modulation. The prototype class D amplifier realized in 0.35 μm digital technology achieves a THD+N of 0.02% when delivering 400 mW to an 8Ω load from VDD=3.6V. The PSRR of the prototype class D amplifier is 80 dB at 217 Hz. Furthermore a filterless method that can eliminate the external LC filter is employed which offers great advantages of saving PCB space and lowering system cost. In addition the prototype class D amplifier can operate in large voltage range with VDD range from 2.5 to 4.2 V in mobile application. The total area of the amplifier is 1.7 mm2.