Miracle-dz/UniFAR-FTUs huggingface dataset:
Tumor Induction with the AT-Acetyl Derivative of 4-Hydroxymethyl-phenylhydrazine, a Metabolite of Agaritine of Agaricus b/sporus1

N'-Acetyl-4-(hydroxymethyl)phenylhydrazine was ad ministered as a 0.0625% solution in drinking water contin uously for the life span of Swiss mice, from 6 weeks of age. Compared to that in untreated controls, in treated animals the lung tumor incidence rose from 15 to 34% in females and 22 to 48% in males, whereas the incidence of blood vessel tumors increased from 8 to 32% in females and from 5 to 30% in males. Histopathologically, the tumors were classified as adenomas and adenocarcinomas of the lungs and angiomas and angiosarcomas of the blood vessels. The commonly eaten mushroom Agaricus bisporus con tains /3-A/-[y-L(+)-glutamyl]-4-hydroxymethylphenylhydra-zine, which under certain conditions yields 4-hydroxyme-thylphenylhydrazine and L-glutamic acid. Since 4-hydrox-ymethylphenylhydrazine is relatively unstable, its acetyl derivative was synthesized for this study. The possible environmental significance of the findings is discussed.
A comparative study of finger vein recognition by using Learning Vector Quantization

Abstract ¾ This paper presents a comparative study of finger vein recognition using various features with Learning Vector Quantization (LVQ) as a classification method. For the purpose of this study, two main features are employed: Scale Invariant Feature Transform (SIFT) and Local Extensive Binary Pattern (LEBP). The other features that formed LEBP features: Local Multilayer Binary Pattern (LmBP) and Local Directional Binary Pattern (LdBP) are also employed. The type of images are also become the base of comparison. The SIFT features will be extracted from two types of images which are grayscale and binary images. The feature that have been extracted become the input for recognition stage. In recognition stage, LVQ classifier is used. LVQ will classify the images into two class which are the recognizable images and non recognizable images. The accuracy, false positive rate (FPR), and true positive rate (TPR) value are used to evaluate the performance of finger vein recognition. The performance result of finger vein recognition becomes the main study for comparison stage. From the experiments result, it can be found which feature is the best for finger vein reconition using LVQ. The performance of finger vein recognition that use SIFT feature from binary images give a slightly better result than uisng LmBP, LdBP, or LEBP feature. The accuracy value could achieve 97,45%, TPR at 0,9000 and FPR at 0,0129.
Inhibition of A^-Butyl-A'-(4-hydroxybutyl)nitrosamine-induced Rat Urinary Bladder Carcinogenesis by a-Difluoromethylornithine1

The effect of oral administration of a-difluoromethylornithine (DFMO), an irreversible ornithine decarboxylase inhibitor, on V-but) I-V-(4-h\ dm\> hm>Iliiilrosamiiir (Bl IB\ )-in<lm-rdrat urinary bladder car cinogenesis was investigated. Four-wk-old male Fischer 344 rats, 30-38 per group, were divided into 3 groups; each group was divided into 3 subgroups. In Group A, 6-wk treatment with 0.05% BHBN in drinking water was followed by either 0.5% (Al), 0.2% (A2), or 0% (A3) DFMO in drinking water for 34 wk. In Group B, Â«Â»administrationin drinking water of 0.01% BHBN and either 0.5% (Bl), 0.2% (B2), or 0% (B3) DFMO was continued for 30 wk. Group C consisted of animals receiving 0.5%, 0.2%, or 0% DFMO in drinking water for 34 wk without prior or cocarcinogen treatment. Bladder tumorigenesis was clearly inhibited by DFMO; tumor incidence was 14 of 37 (38%) in Al, 16 of 38 (42%) in A2, and 31 of 35 (89%) in A3, and 7 of 35 (20%) in Bl, 14 of 35 (40%) in B2, and 28 of 35 (80%) in B3 i/' < 0.01, DFMO groups as compared to the respective control A3 or B3). The average tumor volume was strikingly reduced in Group A rats given DFMO (3.0 mm3 in Al, 5.0 in A2, and 38.6 in A3). Significant suppression of tumor multiplicity (num ber of tumors/tumor-bearing bladder) was observed in DFMO-treated subgroups in Group B (1.1 in Bl, 1.3 in B2, and 1.8 in B3). In both Groups A and B, however, DFMO failed to suppress hyperplastic changes (simple hyperplasia) or preneoplastic lesions (nodulopapillary hyperplasia). Systematic examination of all pertinent organs excluding the brain showed no adverse effects attributable to DFMO treatment except for decrease in body weight (<7%), which was consistently ob served in the groups receiving 0.5% DFMO, and reduction in the com bined weight of the prostate and seminal vesicles (<20%), which was noted in Group B in which exposure to DFMO was started at a younger age. These results indicate that oral administration of DFMO is quite effective in suppressing (or retarding) BHBN-induced carcinogenesis with minimal untoward effects and confirm the similar inhibitory effects demonstrated earlier with the heterotopically transplanted rat urinary bladder system.
Negative Effects and Factors Associated with Postpartum Depression on both Vaginal and Cesarean Delivery Groups

Background and objectives: Postpartum depression is highly prevalent and a broad range of causes including types of delivery are introduced as its source. This study aimed to investigate the relationship between types of delivery and the prevalence of postpartum depression. Methods: This cross-sectional study was carried out in the maternity ward of Sina hospital, Mashhad, in 2014. To this end, 300 women referring to delivery ward were selected through convenient sampling and examined 4 times (immediately after childbirth, 4 weeks after the first assessment, 6 weeks after the second assessment, and 8 weeks after the third assessment) using a demographic questionnaire and Beck's Depression Inventory. In this regard, the first assessment was conducted in person and other assessments were conducted by researcher through making phone calls. Those mothers taking psychiatric medication, having children with serious physical health problem, and having obtained a score above 14 for the first assessment based on the Beck's Depression Inventory as well as those for whom it was not possible to making phone calls were excluded from the study. Data was analyzed using the SPSS software and the confidence level was set at . 05. Findings: There was no significant difference between two groups in terms of education, occupation, economic status, being satisfied with their husbands' support and family and planned and unplanned pregnancy. The prevalence of depression was 10.3 percent two weeks after childbirth and it was 13 percent for mothers during the 8 th weeks after childbirth. However, this difference was not statistically significant. Conclusions: The postpartum depression of high prevalence; therefore, adjusting each of the relevant factors is useful for reducing the incidence of depression.
Guidance impulse algorithms for air bomb control

In this paper, some results of research concerning the development of guidance of bombs were presented. The paper presents conceptions of an impulse (gasodynamic) control system, the measurement unit based on IMU/GPS signals and control algorithms based on predicted trajectories. The presented results of simulation research are based on the numerical model of the bomb and real signals from measurement devices.
Survey of potential-induced degradation in thin-film modules

CdTe and CIGS type modules were tested for potential-‐induced degradation with positive and negative 1,000 V bias applied to the active cell circuit in an 85°C, 85% relative humidity environmental chamber. Both CdTe module types tested exhibited degradation under negative bias. I-‐V curve data indicated the first module type was affected sequentially by shunting followed by a recovery and then by series resistance losses; the second was affected by recombination losses. The first type showed transparent conductive oxide delamination from the glass after about 750 h of stress testing in the environmental chamber and exhibited power degradation within five weeks in field tests with -‐1,000 V system voltage. Performance of CIGS modules differed depending on the technology generation. Under negative bias, the older module design showed an initial 12% (relative) improvement, possibly because of the influx of sodium ions that has been reported to benefit the electrical properties, followed by severe degradation with continued stress testing. The newer design CIGS module exhibited the best stability of the four thin-‐film module types tested with a total loss of 9.5 % (relative) power drop after 3,100 h of test with negative voltage bias, but not clearly by system voltage stress effects considering similar behavior by a sister module in-‐chamber in open-‐circuit condition. Relative rates of current leakage-‐to-‐ground between chamber tests and modules placed outdoors under system voltage stress are compared to extrapolate anticipated coulombs transferred for given extents of degradation of the module power. This analysis correctly placed which module type failed in the field first, but overestimated the time to failure. The performance of modules at 85°C with dark current Imp applied through the cell circuit are discussed with respect to stand-‐alone fielded modules biased to near their maximum power point with load resistors.
Trends in Biometric Technology

Biometrics is playing a major role in automating personal identification system deployed to enhance security in several applications including use of passports, cellular telephones, automatic teller machines, computer systems and driver licenses. The use of biometric features for identification purposes requires that a particular biometric factor be unique for each individual, that it can be readily measured, and that it is invariant over time. When used for personal identification, biometric technologies measure and analyze human physiological and behavioural characteristics. A person’s physiological characteristics are based on direct measurement of a part of the body such as, fingerprint, hand geometry, facial geometry, and eye retinas and irises. Behavioural characteristics are based on data derived from actions, such as speech and signature. The aim of this paper is to provide an overview of the field of biometrics including the current trends. The commonly-used biometrics have been evaluated and some future research directions have been identified.
Value Relevance vis-à-vis Disclosure on Business Combinations and Goodwill Recognized by Publicly Traded Brazilian Companies*

The objective of this study is to examine the value relevance of the level of disclosure on business combinations and goodwill recognized by publicly traded Brazilian companies. The research sample is composed of publicly traded Brazilian companies that carried out any type of business combination, as the acquiring entity, between 2010 and 2013, yielding a total sample of 202 observations. To measure the disclosure level of each, a metric was created based on CPC-15 R1 (2011) to examine certain disclosure items in order to render a greater level of detail. Data collection was carried out using the footnotes to the annual consolidated standardized financial statements (DFPs) available from the São Paulo Stock Exchange (BM&FBOVESPA) website. The results revealed that disclosure levels for business combinations are positively and significantly associated with the stock price of the companies analyzed. As to the recognition of goodwill during business combinations, despite the fact that it represents a significant share of the value of the transactions, no statistical significance explaining stock price behavior was found. It also bears mentioning that the average level of disclosure identified in the explanatory notes in the sample was very low, indicating that companies need to improve when it comes to transparency of information.
ECONOMICS OF NATURE MANAGEMENT AND ENVIRONMENTAL PROTECTION ЕКОНОМІКА ПРИРОДОКОРИСТУВАННЯ ТА ОХОРОНА НАВКОЛИШНЬОГО СЕРЕДОВИЩА

Summary . The investigation of the problems of ecological marketing principles implementation during furniture products manufacturing is carried out in this paper. The distinguishing features of products ecological safety are highlighted. In order to evaluate the prospects of the environmental marketing concept implementation in furniture industry the method of investigation the ecological safety level of furniture production is proposed. The classification of the products ecological safety level from the perspective of ecological certified production is given. The main factors for estimation of products ecological safety such as: the level of company impact on environment according to the types of pollution; the rate of injury, occupational hazards the degree of working conditions influence on the workers health in the production workshop; the products impact on consumer health, etc. The expert survey tools for estimation of the level of the above mentioned factors influence are used, the expert group is formed. According to the results of the expert evaluation it is determined that the greatest environment pollutants are harmful substances, emitted into the air, water and soil by enterprises. The next harmful level includes noise and vibration, but according to expert opinion their impact on the environment is less. The obtained investigation results validity is ensured by determining the expert estimation consistency by means of concordance coefficient calculation. The experts' opinions consistency is considered to be sufficiently high as the concordance coefficient of is 0.81. In this investigation the experts were given the task to evaluate the impact of some factors on the workers’ health in the production workshop, i. e. , the rate of injury while wood sawing, wood dust harmfulness, the influence of adhesives used for wood bonding, the effect of lacquers used for finished products varnishing, as well as working conditions influence. According to the survey, none of the factors has high impact on the workers’ health. Experts also estimated the impact of furniture industry products on consumer health by psychological and physical health indicators and the possibility of injury during operation. The results of the carried out investigation are presented and ways of solving the problem of ensuring products ecological safety are proposed.
Chronically increased G s (cid:1) signaling disrupts associative and spatial learning

The cAMP/PKA pathway plays a critical role in learning and memory systems in animals ranging from mice to Drosophila to Aplysia . Studies of olfactory learning in Drosophila suggest that altered expression of either positive or negative regulators of the cAMP/PKA signaling pathway beyond a certain optimum range may be deleterious. Here we provide genetic evidence of the behavioral and physiological effects of increased signaling through the cAMP/PKA pathway in mice. We have generated transgenic mice in which the expression of a constitutively active form of G s (cid:1) (G s (cid:1) * Q227L), the G protein that stimulates adenylyl cyclase activity, is driven in neurons within the forebrain by the promoter from the CaMKII (cid:1) gene. Despite significantly increased adenylyl cyclase activity, G s (cid:1) * transgenic mice exhibit PKA-dependent decreases in levels of cAMP due to a compensatory up-regulation in phosphodiesterase activity. Interestingly, G s (cid:1) * transgenic mice also exhibit enhanced basal synaptic transmission. Consistent with a role for the cAMP/PKA pathway in learning and memory, G s (cid:1) * transgenic mice show impairments in spatial learning in the Morris water maze and in contextual and cued fear conditioning tasks. The learning deficits observed in these transgenic mice suggest that associative and spatial learning requires regulated G s (cid:1) protein signaling, much as does olfactory
Renin Release: Sites, Mechanisms, and Control

In the adult organism, systemically circulating renin almost exclusively originates from the juxtaglomerular cells in the afferent arterioles of the kidneys. These cells share similarities with pericytes and myoﬁbro-blasts. They store renin in a vesicular network and granules and release it in a regulated fashion. The release mode of renin is not understood; in particular, the involvement of SNARE proteins is unknown. Renin release is acutely increased via the cAMP signaling pathway, which is triggered mainly by catecholamines and other G s -coupled agonists, and is inhibited by calcium-related pathways that are commonly activated by vasoconstrictors. Renin release from juxtaglomerular cells is directly modulated in an inverse fashion by the blood pressure inside the afferent arterioles and by the chloride content in the tubule ﬂuid at the macula densa segment of the distal tubule. Renin release is stimulated by nitric oxide and by prostanoids released by neighboring endothelial and macula densa cells. Steady-state renin concentrations in the plasma are determined essentially by the number of renin-producing cells in the afferent arterioles, which changes in parallel with challenges to the renin-angiotensin-aldosterone system. ANGII: angiotensin Juxtaglomerular(JG)cell: renin-producing cell located in the walls of afferent arterioles at the entrance into the glomerulus Bartter syndrome: a salt-wasting disease caused by defective salt resorption in the thick ascending limb of Henle Gap junction: an intercellular channel allowing the permeation of molecules of up to 1 kDa
Online electromagnetic wave monitoring system for petroleum industry applications

The general demand for automating industrial processes in the oil industry has increased rapidly in parallel with sensors and their underlying technology. Since the early 1980s, the particular problem, which has been representing the extremes in complexity in the oil industry, is the measurement of multiphase flow components, the mixing ratio of oil, water, and gas flowing in a pipeline. Electromagnetic (EM) Wave sensors can provide an attractive solution, because microwave signals can penetrate most materials allowing the measurement to be representative for the cross section of the pipeline. In this thesis, EM wave sensors operating at microwave frequencies are developed for measuring multiphase flow components in a pipeline. These sensors are based on cylindrical cavity, and they use the resonant frequencies related to changes of permittivity to detect and measure (oil, gas, and water) components flowing in a pipeline. Special emphasis has been given to three main design principles. The principle of designing a completely non intrusive sensor, the choice of resonance mode to achieve the best measurement accuracy, and the possibility of designing a new software application to allow online implementation of the sensors. The first principle is shown to allow sensorswith completely non intrusive structures to be designed. The two fundamental modes in cylindrical cavity resonators were therefore analysed. A sensor for measuring the mixture ratio of oil and water flowing in a pipeline is developed. We called it a EM wave (EMW2) for measuring two phase. Both the experiment results and the HFSS results are compared and analysed. A sensor for measuring multiphase flow (oil, gas, and water mixtures) in a pipeline in real time is developed. We called it a EW wave (EMW3) sensor for multiphase fractions measurement. The emphasis is on the measurement accuracy with the desired resonant frequency mode, and the possibility of designing a software programme to explore the functionality of the sensor for online measurement. The accuracy of the sensor measurements is achieved by comparing and analyzing the HFSS simulated results and experimental results. A sensor suitable for measuring online the components of mixtures of (hydrocarbons, gas, and water) flowing in a pipeline is developed based on the EMW3 sensor. We called it a EM Wave monitoring and control system. Consequently, online controlling and monitoring, on the other hand, are achieved and the online results are shown. Finally, the research is concluded and future works is discussed.
PROSPECTS FOR MONETARY INTEGRATION IN THE EURASIAN ECONOMIC UNION

The article reveals the features and prospects of monetary and financial integration within the Eurasian Economic Union. The article highlights the negative aspects, which hinder monetary integration and ways to overcome those. The aim of the study is to identify the degree of readiness of the participating countries to introduce a single currency, as well as the benefits and costs they may face. The object of the research is the Eurasian Economic Union (EAEU), the main economies of which are characterized by raw materials specialization. Research methodology. Theoretical model explains the change in commodity prices that will arise after the introduction of a single currency. The model assumes that export prices will decline after the introduction of a single currency due to the absence of currency risk. Then the volume of exports will increase, but the negative side is that it can bring additional competition to local companies. In empirical part of the study, an attempt was made to quantify the value of currency risk, which is currently present in trade between Russia and Kazakhstan, the largest economies of EAEU. Empirical studies were conducted through OLS regression, as a result of which currency risk was estimated. The practical significance lies in the fact that in the case of the creation of a monetary union on the territory of the EAEU, we can expect a decrease in prices up to 10%, due to the exclusion of currency risk. However, this does not compensate for the negative consequences for the economies. The results of the study lead to the conclusion that due to the lack of basic prerequisites for monetary and financial integration, the introduction of a single currency will not accelerate the development of national economies, but rather create additional risks.
Rapid Discrimination of Fish Pathogenic Vibrio and Photobacterium Species by Oligonucleotide DNA Array

—We developed a low-density oligonucleotide DNA array for the discrimination of 17 Vibrio and 1 Photobacterium species that are pathogenic to aquatic animals. We designed oligonucleotide probes targeting non-coding regions of the intergenic transcribed spacers (ITS) between 16S and 23S ribosomal DNA. Based on the alignment of ITS sequences obtained from the database and the results in this study, three oligonucleotide probes from a bacterial species were designed and immobilized on a nylon membrane. The ITS regions were PCR-amplified using a pair of universal primers, followed by hybridization of the digoxigenin (DIG)-labeled PCR products to the membrane. Specific signals were produced with alkaline phosphatase-conjugated anti-DIG antibody and chemiluminescent substrate. Although cross hybridization was observed, the patterns from each species were different among the species. This DNA array is useful for a rapid and easy discrimination of Vibrio species. The total process, including PCR amplification, can be carried out within a day. Our method enables a global screening of fish pathogenic Vibrio and Photobacterium species
The impact of modular platforms on automobile manufacturing networks

Abstract This paper explores the impact on automobile manufacturing networks of adopting modular platforms to replace the standard platforms used to date. Analysis of European manufacturers’ production networks shows that the use of modular architecture improves coordination by increasing manufacturing mobility and thriftiness ability. The changes resulting from this new modular approach also allow manufacturing capacity to be reorganised and overcapacity to be partially eliminated. From the point of view of production systems, the adaptation of manufacturing processes and facilities to this new architecture should aim to increase flexibility by integrating production around a single platform, allowing for different dimensions and for a larger number of models to be produced in a single plant.