Miracle-dz/UniFAR-FTUs huggingface dataset:
Association Study between Proinflammatory Cytokine Gene Polymorphism and Risk of Recurrent Spontaneous Abortion

To investigate the correlation between inflammatory cytokine gene polymorphisms and the risk of recurrent miscarriage. A total of 120 patients with recurrent spontaneous abortion in our hospital between January 2019 and December 2020 were selected as the recurrent spontaneous abortion group and 120 healthy pregnant women with early pregnancy who visited the hospital during the same period were used as the control group and the genotype of interleukin-18 was detected by single nucleotide polymorphism typing technique and the validation method was Hardy Weinberg’s law of genetic equilibrium was used to verify the genotype of interleukin-18 and the relationship between interleukin-18 genotype and the risk of recurrent spontaneous abortion was analyzed by logistic method. The results showed that the level of interleukin-18 in the recurrent spontaneous abortion group was significantly higher than that in the control group (p 0.05); the interleukin-18 (rs1946519) and interleukin- 18(rs360717) in the control group The actual genotype frequencies of interleukin-18(rs1946519) and interleukin-18 (rs360717) in the control group were also not significantly different from the theoretical values (test values were 0.474 and 0.153, p>0.05); the genotypes of the rs1946519 and rs360717 loci showed significant differences and the recurrent spontaneous abortion group had significantly more A alleles than the control group (p<0.05); rs1946519 and rs360717 locus mutant cases showed significant differences in serum interleukin-17 levels, with AA and TT genotypes showing higher concentrations than other genotypes, respectively (p<0.05); the relative risk of recurrent spontaneous abortion risk in rs1946519 AG and AA gene carriers was 2.468 and 2.468 times higher than that of the GG allele, respectively. The relative risk of recurrent spontaneous abortion in rs360717 TC and TT gene carriers was 1.973 and 1.545 times higher than that of CC allele, respectively and all of them had higher risk of recurrent spontaneous abortion (p<0.05). The rs1946519 polymorphic allele G and rs360717 allele C mutations of interleukin-18 affect the serum hormone levels of patients and lead to an increased risk of recurrent spontaneous abortion in pregnant women. Therefore, interleukin-18 gene polymorphisms may be an important basis for the pathogenesis of recurrent spontaneous abortion and its treatment.
Design of Compact UWB Slotted Hexagonal Monopole Antenna with 3.5/5.5 GHz Dual Band Rejection

A design of compact ultra-wideband (UWB) monopole antenna with dual band-notched characteristics has been reported in this article. The band-notch effect is extremely important for any UWB system to avoid interference with existing narrowband applications such as WiMAX and WLAN. A hexagonal-shaped radiating element has been considered in this design. Two unequal U-shaped slots on the radiating patch have been implemented to achieve dual band-notched filter characteristics. An inverted U-shaped slot has been etched out on the hexagonal patch to achieve band-notch attributes for WiMAX (3.2-3.8 GHz) band. Another slot of having a U-shape has also been engraved on the patch to attain a notched band for WLAN (5.1-5.8 GHz) band. The proposed antenna having a total dimension of 38× 56 mm 2 . Arlon AD300 has been chosen as the substrate which has dielectric permittivity ε r = 3. The height of the substrate is h = 1.524 mm. Full-wave electromagnetic simulation software Ansys HFSS has been used to analyze the radiation characteristics of the structure. The proposed antenna successfully covers the FCC allocated UWB frequency spectrum by operating over the frequency band between 2.6 GHz to 11.4 GHz (VSWR < 2) which depicts the bandwidth of 120 %. The designed antenna exhibits good gain and bidirectional radiation patterns.
Modeling Volatility Spillovers Between Stock Returns, Oil Prices, And Exchange Rates: Evidence from Russia and China

This study investigates the interdependence between crude oil fluctuations and stock return dynamics of major oil BRICS stock market returns namely China and Russia, over the last turbulent period ranging from September 2001 to March 2019. We used a VAR-GARCH model that allows for simultaneous spillover in volatility and return, under the Student’s t-distribution. In addition to crude oil prices, foreign exchange rates are so included in the model to strengthen its explanatory power. The results revealed that the Chinese and Russian markets are sensitive to their past own shocks and past own conditional volatility. Furthermore, the fundamental matter more than news in these markets. In contrast, considering the Chinese market, we found that in the long-run future volatility cannot be predicted by conditional crude oil and its foreign exchange rate volatilities. Similarly, the Russian market is insensitive to the foreign exchange rate and crude oil. Our findings are useful for regional and international investors needing forecasts of oil BRICS stock market futures volatility to optimize investment choices.
Sulphur chemistry in the L1544 pre-stellar core

The L1544 pre-stellar core has been observed as part of the ASAI IRAM 30m Large Program as well as follow-up programs. These observations have revealed the chemical richness of the earliest phases of low-mass star-forming regions. In this paper we focus on the twenty-one sulphur bearing species (ions, isotopomers and deuteration) that have been detected in this spectral-survey through fifty one transitions: CS, CCS, C3S, SO, SO2, H2CS, OCS, HSCN, NS, HCS+, NS+ and H2S. We also report the tentative detection (4 {\sigma} level) for methyl mercaptan (CH3SH). LTE and non-LTE radiative transfer modelling have been performed and we used the nautilus chemical code updated with the most recent chemical network for sulphur to explain our observations. From the chemical modelling we expect a strong radial variation for the abundances of these species, which mostly are emitted in the external layer where non thermal desorption of other species has previously been observed. We show that the chemical study cannot be compared to what has been done for the TMC-1 dark cloud, where the abundance is supposed constant along the line of sight, and conclude that a strong sulphur depletion is necessary to fully reproduce our observations of the prototypical pre-stellar core L1544.
Recalling the universal health coverage vision and equity in the COVID-19 vaccine distribution plan

The COVID-19 pandemic has changed the world in so many ways since 2019 when the first case was recorded. COVID-19 pandemic has impacted negatively on economy, health, education and infrastructure globally. COVID-19 vaccine was developed with the aim of stopping the pandemic and allowing the rebuilding of our societies and economies. The vaccine was rolled out in December 2020 and the distribution plan appears to be skewed in favour of high income countries. This paper highlights the need for consideration of the principles of equity and universal health coverage in the distribution plan of the vaccine. It emphasizes the need to ensure that the interests of citizens of developing and low income countries are well protected. The paper concludes that issues of disparity in economic status of countries entering agreement with the vaccine manufacturing companies, absence of logistic support among others should not be a barrier to ensuring equitable access to vaccine for all consistent with the sustainable development goal 3.7.
La Mortandad de las MiPyMEs en Colombia y México

En el presente artículo se nutre de información obtenida en los medio de información oficial, así como de otras fuentes no primaria, esto con la finalidad de identificar el comportamiento de las MiPyMEs, tanto en México como en Colombia, particularmente en sus efectos respecto a la mortandad de las empresas o negocios que se identifican en ambas naciones, equiparando como una de la problemática más detonante, la falta de una administración financiera adecuada, lo cual indica que si se aplicara de manera eficiente, podrá disminuir de manera importante la deserción de estas, y se podrá fomentar de manera confiable su creación, desarrollo, consolidación, viabilidad, productividad, sostenibilidad, competitividad y sustentabilidad, incrementado su esperanza de vida, por ello, la intensión de identificar el comportamiento de las microempresas en estos dos países para localizar algunas factores que permitan disminuir y en su caso eliminar la mortandad de esta MiPyMEs.
The last meal of Tollund Man: new analyses of his gut content

Abstract The last meal of Tollund Man, a bog body from Early Iron Age Denmark, has been re-examined using new analyses of plant macrofossils, pollen, non-pollen palynomorphs, steroid markers and proteins found in his gut. Some 12–24 hours before he was killed, he ate a porridge containing barley, pale persicaria and flax, and probably some fish. Proteins and eggs from intestinal worms indicate that he was infected with parasites. Although the meal may reflect ordinary Iron Age fare, the inclusion of threshing waste could possibly relate to ritual practices. This re-analysis illustrates that new techniques can throw fresh light on old questions and contribute to understanding life and death in the Danish Early Iron Age.
Data Augmentation via Face Morphing for Recognizing Intensities of Facial Emotions

Being able to recognize emotional intensity is a desirable feature for a facial emotional recognition (FER) system. However, the development of such a feature is hindered by the paucity of intensity-labeled data for model training. To ameliorate the situation, the present study proposes using face morphing as a novel way of data augmentation to synthesize faces that express different degrees of a designated emotion. Such an approach has been successfully validated on humans and machines. Specifically, humans indeed perceived different levels of intensified emotions in these parametrically synthesized faces, and FER systems based on neural networks indeed showed improved sensitivities to intensities of different emotions when additionally trained on the synthesized faces. Overall, the proposed data augmentation method is not only simple and effective but also useful for building FER systems that recognize facial expressions of mixed emotions.
Morphology and structure of WS2 nanosheets prepared by solvothermal method with surfactants

ABSTRACT In this work, a modified solvothermal method has been developed to synthesize few layers of tungsten disulfide-nanosheets(WS2-NS). Different types of surfactants were also employed in the modified solvothermal method with respect to the original procedure. As-prepared WS2 samples were characterized by XRD, TEM, and Raman spectrum. The results showed that the obtained WS2-NS were consisted of 1–10 atomic layers. Importantly, the effects of surfactant on the morphology formation of WS2-NS were investigated. A possible growth mechanism is presented to explain the formation of WS2-NS.
Development of Seawater Intrusion Vulnerability Assessment for Averaged Seasonality of Using Modified GALDIT Method

Climate change and anthropogenic activities are necessitating accurate diagnoses of seawater intrusion (SWI) to ensure the sustainable utilization of groundwater resources in coastal areas. Here, vulnerability to SWI was assessed by classifying the existing GALDIT into static parameters (groundwater occurrence (G), aquifer hydraulic conductivity (A), and distance from shore (D)) and dynamic parameters (height to groundwater-level above sea-level (L), impact of existing status of seawater intrusion (I), and aquifer thickness (T)). When assessing the vulnerability of SWI based on observational data (2010–2019), 10-year-averaged data of each month is used for GALDIT dynamic parameter for representing the seasonal characteristics of local water cycles. In addition, the parameter L is indicated by the data observed at the sea-level station adjacent to the groundwater level station. The existing GALDIT method has a range of scores that can be divided into quartiles to express the observed values. To sensitively reflect monthly changes in values, the range of scores is divided into deciles. The calculated GALDIT index showed that the most vulnerable month is September, due to relatively low groundwater level. The proposed method can be used to apply countermeasures to vulnerable coastal areas and build water resources management plan considering vulnerable seasons.
Epidemiological Trends of Urinary Tract Infections at the Global, Regional, and National Levels from 1990-2017: A Population-Based Study

BackgroundUrinary tract infections (UTIs) are some of the most common infections worldwide and consume a lot of medical resources every year. However, there were a lack of available data on its incidence and disease burden. We armed to investigate incidence, mortality, and disability adjusted life-years (DALYs) of urinary tract infections (UTIs) from 1990 to 2017.MethodsWe extracted data from the Global Burden of Disease Study 2017, then calculated estimated annual percentage changes (EAPC) of age-standardized incidence rate (ASIR), age-standardized death rate (ASDR), and age-standardized DALYs rate at global, national, regional, and socio-demographic index (SDI) level.ResultsFrom 1990 to 2017, the globally incident cases (+52.09%), death cases (+140.10%), and DALYs (+69.65%) of UTIs all increased. The ASIR, ASDR, and age-standardized DALYs rate showed upward trends with the EAPC of +0.10 (95%CI: 0.07 to 0.12), +0.72 (95%CI: 0.65-0.78), and +0.06 (95%CI: -0.05 to 0.16), respectively. The ASIR decreased only in the high-middle SDI quantile (-0.26, 95%CI: -0.3 to -0.23). United Arab Emirates had the largest increase of DALYs (+835.04%), but Bulgaria had the largest decrease (-80.74%). EAPC for incidence and mortality were below 0 mainly in Europe and East Asia. In 2017, the incident cases (+3.44 times), the deaths (+1.31 times), and DALYs (+1.21 times) were all higher in females than males. The incident cases were mainly concentrated in 15-49 years old; DALYs and mortality were higher in over 80 age groups.Conclusions﻿Globally, the burden of UTIs increased from 1990 to 2017, especially in females; however, distinct varies were observed in different regions and countries. The infants and elders are easier to die when they suffer from UTIs.
Determinants of Dividend Payout Ratio: Empirical Evidence from Ethiopian Private Banks"

This study empirically examines the effect of firm specific and macroeconomic factors on dividend payout decision of the Ethiopian private commercial banks. Using panel data on eight private banks covering 2008 – 2016, the random-effect regression model results revealed that liquidity, bank size and inflation have positive and statistically significant impacts on dividend payout decision. But, the regression results suggest that bank’s growth and investment opportunity have negative and statistically significant impact on dividend payout decision in Ethiopian private banks.
Der Azubi-Coach: Theoretische Rahmung eines Projekts zur Förderung sozialer Kompetenzen in regionalen Ausbildungsbetrieben des Handwerks

Der Fachkraftemangel in Deutschland betrifft insbesondere auch die Branche des Handwerks. Dieses Problem wird durch die hohen Quoten an Ausbildungsabbruchen und Vertragslosungen noch verscharft. Diese Problematik steht im Mittelpunkt des Projekts der ‚Azubi-Coach im Handwerk‘, das vom Bildungszentrum Handwerk und Bildung in Sondershausen durchgefuhrt wurde. In diesem Artikel wird ausgehend vom Forschungsstand und den empirischen Ergebnissen der Umfrage im Projekt die theoretische Basis fur das Konzept des Azubi-Coaches entwickelt. Diese theoretische Rahmung greift auf Ergebnisse der Commitmentforschung zuruck und pruft die Frage, inwiefern ein Azubi-Coach, als zentrale Bezugsperson und Mentor dazu beitragen kann, die Bindung der Auszubildenden an den Betrieb zu erhohen. Vor diesem Hintergrund wird ein Ausbildungskonzept entwickelt, das Vertreter der auszubildenden Betriebe befahigen soll, die Rolle eines Azubi-Coaches kompetent einnehmen zu konnen.
Effects of Hydrogen on the Phase Relations in Fe‐FeS at Pressures of Mars‐Sized Bodies

The large radius, and therefore low density, of the Martian core found in the InSight mission data analysis highlights the importance of considering other light elements besides sulfur (S), which has been considered as the main light element for Mars for decades. Hydrogen (H) is abundant in the solar system and becomes siderophile at high pressures. Although Fe‐S and Fe‐H systems have been studied individually, the Fe‐S‐H ternary system has only been investigated up to 16 GPa and 1723 K. We have investigated the Fe‐S‐H system at pressures and temperatures (P‐T) relevant to the cores of Mars‐sized planets (up to 45 GPa and well above the melting temperature of FeS) in the laser‐heated diamond anvil cell combined with in situ synchrotron X‐ray diffraction. We found that sufficient hydrogen leads to the disappearance of Fe3S at high P‐T. Instead, separate Fe‐H and Fe‐S phases appear at 23–35 GPa. At pressures above 35 GPa, we found a new phase appearing while Fe‐S phases disappear and Fe‐H phases remain. Our analysis indicates that the new phase likely contains both S and H in the crystal structure (tentatively FeSxHy where x ≈ 1 and y ≈ 1). The observed pressure‐dependent changes in the phase relation may be important for understanding the structure and dynamics of the Martian core and the cores of Mars‐sized exoplanets.
Three basic types of fluorescence microscopy and recent improvement

Fluorescence microscopy is one of the most used imaging modalities in molecular biology and living specimens. To increase image contrast and spatial resolution, different type of fluorescence microscopy has been developed. This review introduces three main types of fluorescence microscopy: wild-field microscopy, confocal microscopy, and total internal reflection fluorescence microscopy. The basic principles are similar but with different modifications, which also indicates their attributes and limitation. The recent improvement on these microscopies is also discussed. Some most recent techniques show advance in overcoming common fluorescence microscopy's weakness, and future perspectives are also discussed.
Iterative learning Control of Trajectory Tracking of Robot Manipulator Based the SoC Platform Integrated Motor Drive and Motion Control

With the development of SoC technology, the integration of FPGA+ARM has become the development direction of SoC. For the characteristics of integrated multi-axis motion control and motor drive, this paper selects Xilinx ZYNQ-7020 System-onchip (SOC) with integrated dual-core ARM CPU and FPGA as the hardware platform control chip, an arm core motor drive algorithm. Another ARM core completes the interactive function and motion control, and the FPGA to complete the multi-axis hardware current loop and improve the system bandwidth. The iterative learning control (ILC) technology is widely used in robots to reduce the trajectory error of robots performing repetitive tasks. Using P-type iterative learning ILC combined with feedback control , which can compensate for nonrepeating disturbance. Finally, analysis of experimental results shows that iterative learning control combined with feedback control can significantly improve tracking accuracy.
The Influence of Chitosan Concentration on Synthesis of Hydroxyapatite Scaffold on Crystallinity and Surface Morphology

Hydroxyapatite (HA) is a bioceramic material having a chemical formula (Ca10(PO4)6(OH)2) similar to the chemical structure of bone and hard tissue in humans. Recently, HA-scaffold has been intensively developed by many researchers due to its potential application in dealing with tissue injured. The implantation of HA-scaffold into bone defect aims to help and stimulate the growth of new bone tissue. Crystallinity and microstructure are properties that need to be considered to synthesis HA scaffold. Although, HA is biocompatible and osteoconductive but low biodegradable, to solve these problems added chitosan. Chitosan is a biopolymeric material with specific properties, in terms of biocompatible, non-toxic, osteoconductive, biodegradable, and not carcinogenc. In addition, a natural polymeric chitosan has similarities with the extracellular matrix, in terms of good biological performance and inherent cellular interactions. In this study, HA-scaffold was synthesized using Ca(OH)2 as the raw material of natural calcite mineral, H3PO4, and a solid polyurethane polymer (sponge) as forming of pores by sol-gel method. The addition of chitosan concentration of 0 %, 2 % and 3 % in hydroxyapatite scaffold evaluated its influences on crystallinity and surface morphology. The phase, crystallinity and crystal size are evaluated by XRD. Functional groups in HA scaffold and HA compounds were evaluated with FTIR. The results showed that HA has Ca/P ratio of 1.64. The addition of chitosan concentration caused the decrease of crystallinity and increased the pore size. Meanwhile the crystal sizes were obtained: 49.99 nm (HA), 54.37 nm (HA-scaffold without chitosan), 54.98 nm (HA-scaffold with 2% chitosan), and 40.44 nm (HA-scaffold with 3 % chitosan).
Overconfidence and Generosity: An Online Experiment on Covid-19

Under the backdrop of the pandemic of COVID-19, people have different predictions of the future condition and understanding of the current status. In this paper, findings from an online experiment show how overconfidence can play an important role in terms of decision-making of the pandemic: among the main findings from data analysis, self overconfidence significantly increases donations. Also, with the growth of age, people tend to donate more while as they advance the education level, people prefer to donate less. The results of this research can further inform policymakers on individuals’ behaviors during a negative economic shock.
Efficacy of Autologous Stem Cell Transplantation for the Treatment of Multiple Myeloma in HIV-Positive Patients

Prior to the advent of anti-retroviral therapy (ART), autologous stem cell transplant (ASCT) was relatively contraindicated for multiple myeloma (MM) patients with human immunodeficiency virus (HIV) due to issues associated with stem cell harvest and the risk of opportunistic infections. With the widespread use of ART for control of HIV, ASCT is now the preferred treatment for relapsed lymphoma, the leading hematopoietic malignancy associated with HIV/AIDS. Hence, MM patients with HIV controlled by ART may benefit equally from aggressive combination treatment of chemotherapy and ASCT. This study seeks to evaluate the clinical course and treatment outcomes of patients with HIV and MM treated with ASCT. Five male patients with average age 53.2 years were included in this study. Patients were diagnosed with HIV prior to diagnosis of MM and were appropriately treated with ART prior to ASCT. All patients had undetectable HIV viral load (VL) prior to ASCT, and remained undetectable after ASCT. Adequate CD34+ stem cells were collected. Patients received high dose melphalan (200 mg/m2) followed by ASCT. ART was continued during ASCT. Patients experienced usual ASCT toxicities including diarrhea, mucositis, and neutropenic fever. All patients had normal neutrophil and platelet engraftments. 60% of patients had very good partial response or better after ASCT. All patients received post ASCT maintenance until progression/toxicity/patient decision. As of December 2020, 2 patients have died 51 and 85 months from ASCT due to other causes. The 3 remaining patients are alive 5-7 years after ASCT. MM patients with concurrent HIV infection that is controlled on ART would benefit from aggressive treatment with chemotherapy and ASCT, with continued ART as they tolerate ASCT as well as myeloma patients without HIV infection.