Miracle-dz/UniFAR-FTUs huggingface dataset:
Pain Following Single-bundle versus Double-bundle Anterior Cruciate Ligament Reconstruction: A Systematic Review

BACKGROUND: Double-bundle (DB) anterior cruciate ligament reconstruction (ACLR) has been known to result in better functional outcomes, joint stability, and lower revision rates compared to single-bundle (SB) ACLR. However, given the increased invasiveness and damage to the surrounding tissue area, it is proposed that it may be associated with increased pain. AIM: This review aims to gather all studies and literature that reported pain as an outcome when comparing SB versus DB ACLR. METHODS: Literature searching was conducted across seven search engines for studies reporting pain as an outcome and comparing SB versus DB ACLR. RESULTS: Eight studies met the eligibility criteria and were included in the study. Overall, the studies show variable findings regarding pain in DB compared to SB ACLR, with the only statistically significant results from two studies indicating that DB ACLR is associated with more pain than SB ACLR. CONCLUSION: Based on the limited evidence available, no conclusions can be made regarding the pain experienced between people receiving either procedure. This constitutes a need for additional studies with increased follow-up time periods, larger sample size, and better study design. Edited by: Eli Djulejic Citation: Pontoh LAP, Ismail HD, Fiolin J, Yausep OE. Pain Following Single-bundle versus Double-Bundle Anterior Cruciate Ligament Reconstruction: A Systematic Review. Open Access Maced J Med Sci. 2021 May 14; 9(F):153-162. https://doi.org/10.3889/oamjms.2021. 5995
AT CIKM WORKSHOP ON DATA AND BIAS ( DAB ) Fairness and Transparency in Ranking ∗

Ranking in Information Retrieval (IR) has been traditionally evaluated from the perspective of the relevance of search engine results to people searching for information, i.e., the extent to which the system provides “the right information, to the right people, in the right way, at the right time. ” However, people in current IR systems are not only the ones issuing search queries, but increasingly they are also the ones being searched. This raises several new problems in IR that have been addressed in recent research, particularly with respect to fairness/non-discrimination, accountability, and transparency. This is a summary of some these initial developments.
Generation Z Students : Will They Change Our Computer Science and IT Classrooms ?

The students who are age 21 years and below, born either in 1997 or after, are the ones belonging to the new category of Generation Z. Naturally, in regards to any other groups of generational cohorts, the Generation Z students have their unique and distinct characteristics which subsequently influence the approach that they have towards work and education. The paper presents information about the Generation Z students’ personalities, their views about work and education, the need of information faculty to understand about the students, and the implications for computer science and IT educators.
Nonlinear Wave Evolution in Interaction with Currents and Viscoleastic Muds

A numerical model is extended to investigate the nonlinear dynamics of surface wave propagation over mud in the presence of currents. A phase-resolving frequency-domain model for wave-current interaction is improved to account for wave modulations due to viscoelastic mud of arbitrary thickness. The model compares well with published laboratory data and performs slightly better than the model with viscous mud-induced wave damping mechanism. Monochromatic and random wave simulations are conducted to examine the combined effect of currents, mud-induced wave dissipation and modulation, and nonlinear wave-wave interactions on surface wave spectra. Results indicate that current effects on wave damping over viscoelastic mud is not as straightforward as that over viscous mud. For example, while opposing currents consistently increase damping of random waves over viscous mud, they can decrease damping over viscoelastic mud due to high variations in frequency-dependent damping stemming from mud’s elasticity. It is shown that a model that assumes the mud layer to be thin for simplification can overestimate wave damping over thick mud layers.
C O ] 2 5 Ju l 2 00 3 Planar Minimally Rigid Graphs and Pseudo-Triangulations

Pointed pseudo-triangulations are planar minimally rigid graphs embedded in the plane with pointed vertices (adjacent to an angle larger than π). In this paper we prove that the opposite statement is also true, namely that planar minimally rigid graphs always admit pointed embeddings, even under certain natural topological and combinatorial constraints. The proofs yield efficient embedding algorithms. They also provide to the best of our knowledge the first algorithmically effective result on graph embeddings with oriented matroid constraints other than convexity of faces. These constraints are described by combinatorial pseudo-triangulations, first defined and studied in this paper. Also of interest are our two proof techniques, one based on Henneberg inductive constructions from combinatorial rigidity theory, the other on a generalization of Tutte’s barycentric embeddings to directed graphs.
An Online Approach for DNA Sequencing Error Correction via Disk Based Index ∗

DNA sequencing has been widely used in many biological studies such as gene expression analysis and biomedical diagnostics. To solve the problem of sequencing errors produced by a sequencer, researchers perform error correction as a first step in sequence analysis. To overcome the scalability problem of existing memory based error correction methods, a disk based sequencing error correction method, called the DiskBQcor, was recently proposed. It utilizes a disk based index tree to store k -mers from sequencing reads. It then analyzes the results of special box queries run on the index tree to efficiently correct sequencing errors. As an offline approach, the DiskBQcor corrects errors after all the k-mers for a given genome dataset are inserted into the index tree. In this paper, we present an online approach, called the DiskBQcor∗, for sequencing error correction to better utilize computing resources. It extends the DiskBQcor by introducing an online analysis process during which sequencing errors are identified and corrected in an online fashion. The relevant correction algorithms, statistical measures, and error identifying strategies are discussed. Our experiments demonstrate that the proposed online method is quite promising in error correction for sequencing genome data on disk. keywords: DNA sequencing error correction, diskbased index structure, box query, online method.
Synthesis and biological evaluation of biotin-conjugated Portulaca oleracea polysaccharides

Biotinylated Portulaca oleracea polysaccharide (Bio-POP) conjugates were successfully prepared by the esterification reaction. The biotinylated polysaccharide products were an off-white powder with an average degree of substitution of 42.5%. After grafting biotin onto POP, the thermal stability of Bio-POP conjugates was much higher than that of POP and the surface topography of Bio-POP was a loose and porous cross-linked structure. The cytotoxicity assay in vitro demonstrated that POP, biotin, and Bio-POP conjugates exhibited different cytotoxicity to HeLa, MCF-7, LO-2, and A549, in particular POP inhibited the growth of the A549 cell line more than other cell lines. The nuclear staining method demonstrated that Bio-POP conjugates can interfere with the apoptosis of A549 cells to some extent and the immunofluorescence staining photograph illustrated that Bio-POP conjugates induced A549 cells to exhibit immune activity. Therefore, the combination of biotin and Portulaca oleracea polysaccharides had immune synergistic therapeutic effects on A549 cells and can be applied in the field of anti-tumor conjugate drugs.
Effects of sense and antisense centromere/kinetochore complex protein-B (CENP-B) in cell cycle regulation

This paper investigates the effects of sense and antisense centromere/kinetochore complex protein-B (CENP-B) in cell cycle regulation. Full-length cenpb cDNA was subcloned into pBI-EGFP eukaryotic expression vector in both sense and antisense orientation. HeLa-Tet-Off cells were transfected with sense or antisense cenpb vectors. Sense transfection of HeLa-Tet-Off cells resulted in the formation of a large centromere/kinetochore complex, and apoptosis of cells following several times of cell division. A stable antisense cenpb transfected cell line, named HACPB, was obtained. The centromere/kinetochore complex of HACPB cells became smaller than control HeLa-Tet-Off cells and scattered, and the expression of CENP-B was down-regulated. In addition, delayed cell cycle progression, inhibited malignant phenotype, restrained ability of tumor formation in nude mice, and delayed entry from G2/M phase into next G1 phase were observed in HACPB cells. Furthermore, the expression of cyclin-dependent kinases (CDKs), cyclins, and CDK inhibitors (CKIs) were modulated during different phases of the cell cycle. CENP-B is an essential protein for the maintenance of the structure and function of centromere/kinetochore complex, and plays important roles in cell cycle regulation.
Generiranje niza pseudoslučajnih brojeva

a) Za niz brojeva ćemo reći da je nepredvidljiv ako znajući bilo koji početak tog niza nikako ne možemo predvidjeti sljedeći član tog niza (osim potpuno slučajno). Malo preciznije, ako znamo X0 , X1 , X2 , X3 ,. , Xn , ne možemo (lagano) predvidjeti sljedeći član Xn+1 bez obzira na to koliko velik n bio. b) Za niz brojeva ćemo reći da je uniforman ako se (pojednostavnjeno rečeno) u njemu sve moguće vrijednosti pojavljuju u podjednakim omjerima. Ukratko, ako promatramo (dovoljno dugačak) niz brojeva kojeg dobivamo bacanjem standardne igraće kockice, onda očekujemo da se u njemu pojave svi brojevi od 1 do 6 i da se niti jedan broj u nizu ne pojavljuje mnogo više ili manje od nekog drugog broja.
Full Parameter Estimation for Permanent Magnet Synchronous Motors

This article elaborates a novel online full parameter estimation method for permanent magnet synchronous motors (PMSMs). Usually, only two parameters can be estimated using voltage functions in the <italic>d-q</italic> frame due to the problem of rank deficiency. The α-β frame possesses the inherent advantage that full motor parameters can be estimated using voltage functions during steady and transient states. An algorithm based on recursive least squares in the α-β frame is proposed to estimate full motor parameters, including stator resistance, <inline-formula><tex-math notation="LaTeX">$d$</tex-math></inline-formula>-axis and <inline-formula><tex-math notation="LaTeX">$q$</tex-math></inline-formula>-axis inductances, and flux linkage simultaneously. Simulation and experimental results on the PMSM drive system are presented to verify the effectiveness of the proposed algorithm. Compared with the method in the <italic>d-q</italic> frame, the superiority of the proposed method in terms of faster convergence rate, less computational cost, and high accuracy is demonstrated.
Snapshot of Clinical Implications of p16 Overexpression in Carcinogenesis

Molecular markers are needed to decide the treatment plans of certain cancer types when the histological and other clinical diagnoses are not sufficient to decide the tumor nodular metastasis (TNM) stage. The ubiquitous p16 gene is one of them gained popularity by fulfilling criteria to be a useful biomarker. Over expression of p16, to compensate the inactivity of another two tumor suppressor genes (TSG)s, pRb and p53 due to the integration of E7 and E6 high risk Human Papilloma viral oncoprotein respectively into the host keratinocytes is useful to consider the clinical impact of p16 biomarker in carcinogenesis. The p16 immunohistochemistry helps the diagnosis as well as prognosis of cervical and oropharyngeal squamous cell carcinoma, though there are ambiguities in the cutoff values of p16 positivity. There is also a re-emerging interest on clinical impact of p16 positivity in lung, breast, and colorectal cancer types. High risk HPV genotypes have been already established as the aetiological agents of cervical, other rare ano-genital and oropharyngeal (especially tonsils and base of the tongue) cancers. The HPV associated subset of head and neck cancers demonstrate a unique tumor biology, when compared with HPV non associated ones thus, most effective treatment planning including counselling is much needed to maximize the overall survival of HPV associated cancer patients, in the era of personalized precision medicine. In the shed of light, this communication glimpses on clinical implications of p16 overexpression in carcinogenesis not limiting to cervical and a subset of head and neck carcinomas (HNSCC).
Surface-wave tomography of the Emeishan large igneous province (China): Magma storage system, hidden hotspot track, and its impact on the Capitanian mass extinction

Large igneous provinces (LIPs) are commonly associated with mass extinctions. However, the precise relations between LIPs and their impacts on biodiversity is enigmatic, given that they can be asynchronous. It has been proposed that the environmental impacts are primarily related to sill emplacement. Therefore, the structure of LIPs’ magma storage system is critical because it dictates the occurrence and timing of mass extinction. We use surface-wave tomography to image the lithosphere under the Permian Emeishan large igneous province (ELIP) in southwestern China. We find a northeast-trending zone of high shear-wave velocity (Vs) and negative radial anisotropy (Vsv > Vsh; v and h are vertically and horizontally polarized S waves, respectively) in the crust and lithosphere. We rule out the possibilities of rifting or orogenesis to explain these seismic characteristics and interpret the seismic anomaly as a mafic-ultramafic, dike-dominated magma storage system of the ELIP. We further propose that the anomaly represents a hidden hotspot track that was emplaced before the ELIP eruption. A zone of higher velocity but less-negative radial anisotropy, on the hotspot track but to the northeast of the eruption center in the Panxi region, reflects an elevated proportion of sills emplaced at the incipient stage of the ELIP. Liberation of poisonous gases by the early sill intrusions explains why the mid-Capitanian global biota crisis preceded the peak ELIP eruption by 2–3 m.y.
Three Internal Barriers to Technology Integration in Education: Opinion, Attitude and Self-Confidence

This case study examination assessed the significant contributions of college resources regarding students’ character development within a liberal arts institutional setting. The effects of attributed contributions from various interactions and experiences are analyzed within the context of Astin’s [1] input-environment-outcome model. Data elements from student participants in their senior undergraduate year were utilized and extracted from merged longitudinal databases that included matching student responses from Student Information Forms (SIF) and College Senior Surveys (CSS), both instruments from the Higher Education Research Institute. The results of this case study confirmed many established results concerning student character development, yet also continue to raise questions regarding which institutional relationships and experiences have the greatest impact in contributing to its enhancement.
Does Migration Interfere with Children's Progress in School?.

Frequent interstate migration is found to be associated with an increased likelihood of being enrolled below the modal grade for age among children whose parents are not college graduates. For children of college graduates frequent interstate migration is associated with a reduction of grade skipping. Interstate migration is most likely to be undertaken by well-educated persons whose children tend to do well in school, and for this reason children who have made frequent interstate moves are less likely to be behind in school than less mobile children. The overrepresentation of the highly educated among long-distance movers is offered as partial explanation of why growing communities tend to have children of above average scholastic ability.
Tracking control for flexible joint robots based on adaptive fuzzy compensation with uncertain parameters

This article presents a control scheme for flexible joint robots which has uncertain parameters based on adaptive fuzzy compensation. Considering the unknown parameters, the proposed state feedback control approach utilizes measured variables to establish a cascade structure that is based on simplified dynamics. After reducing the number of fuzzy rules, the adaptive fuzzy logic system is added as compensation to decrease the approximated errors, and the robust terms are also used to enhance the robustness of closed‐loop system. Then, the global asymptotic stability could be confirmed through Lyapunov stability principle and Barbalat's lemma. Compared with the other two controllers, the proposed control method has not only higher position accuracy and better dynamic performance but also robustness to the approximation of motor inertia, friction torque and link torque. Some simulation experiments are conducted to show the validity of the proposed scheme.
‘That hat means a lot more than a hat for some of us’: Gay Latino collegians in the era of Trump

ABSTRACT While there has been significant media coverage on Trump and his administration’s stance on LGBTQ and Latina/o communities, there has been limited empirical research on the matter. In this qualitative study, I employed racist nativism and queer critical theory to examine the lives of gay Latino men in college, with a focus on their race/ethnicity and sexuality, within the polarizing racial climate under Trump. Consistent with the conceptual frameworks, I elucidate the findings through in-depth critical race testimonios while accounting for systemic oppression (e.g., heterosexism, racism, white supremacy). Findings revealed the following themes: 1) fear as a result of the intersections of racist nativism and homophobia and 2) racialized incidents: Trumpists on campus. Implications for research and practice are discussed.
Ensemble Learning Based Methods for Crown Prediction of Hot-Rolled Strip

The strip crown or profile generated by the cooperation of finishing mills is affected by many factors, so obtaining an accurate crown has always been a challenge in hot strip rolling. As a kind of solution to ensure the crown accuracy of hot-rolled strips, this study develops three novel strip crown prediction models using the well-performing and efficient tree-based ensemble learning algorithms, including Random Forest (RF), eXtreme Gradient Boosting (XGBoost), and Light Gradient Boosting Machine (LightGBM), respectively. The comparison results of measured and predicted strip crown show that all developed strip crown prediction models perform well based on the accurate extraction of key features as model inputs, the collection and pre-processing of a large amount of modeling data, and the use of the Bayesian optimization technique. By comparison, the LightGBM model with both high efficiency and high accuracy is considered the most recommended method for hot-rolled strip crown prediction. Besides, according to the feature importance scores of the input variables calculated based on the LightGBM model, the impact levels of each input variable on the strip crown are measured, and the calculation results fit well with the classical hot rolling theory indicating the modeling route as a reliable one.
A comprehensive study of secondary and tertiary vortex phenomena of flow past a circular cylinder: A Cartesian grid approach

This study envisages undertaking a comprehensive simulation of the flow past an impulsively started circular cylinder with special emphasis on vortex dynamics in the secondary and tertiary level. A recently developed second order spatially and temporally accurate compact finite difference scheme on a nonuniform Cartesian grid has been used to discretize the transient Navier–Stokes equations governing the flow. The grid is generated in such a way that the cylinder boundary passes through the grid points, thus dispensing with the need to use the immersed interface approach on a Cartesian grid. High quality simulations are accomplished for a wide range of Reynolds numbers (Re) from 5 ≤ R e ≤ 10 000 in the laminar regime, including the periodic flow characterized by von Karman vortex street. The α, β, sub-α, and sub-β phenomena, which are the trademark of the secondary and tertiary vortex dynamics associated with such flows, are studied in detail. Our results are compared with existing experimental and numerical results, and close comparison is obtained in all the cases exemplifying their accuracy. In the process, for the first time, we also provide a tabular documentation of the early stages of the flow for R e ≥ 700.
Design Strategies and Architectures for Ultra-Low-Voltage Delta-Sigma ADCs

The design of ultra-low voltage analog CMOS integrated circuits requires ad hoc solutions to counteract the severe limitations introduced by the reduced voltage headroom. A popular approach is represented by inverter-based topologies, which however may suffer from reduced finite DC gain, thus limiting the accuracy and the resolutions of pivotal circuits like analog-to-digital converters. In this work, we discuss the effects of finite DC gain on ultra-low voltage ΔΣ modulators, focusing on the converter gain error. We propose an ultra-low voltage, ultra-low power, inverter-based ΔΣ modulator with reduced finite-DC-gain sensitivity. The modulator employs a two-stage, high DC-gain, switched-capacitor integrator that applies a correlated double sampling technique for offset cancellation and flicker noise reduction; it also makes use of an amplifier that implements a novel common-mode stabilization loop. The modulator was designed with the UMC 0.18 μm CMOS process to operate with a supply voltage of 0.3 V. It was validated by means of electrical simulations using the CadenceTM design environment. The achieved SNDR was 73 dB, with a bandwidth of 640 Hz, and a clock frequency of 164 kHz, consuming only 200.5 nW. It achieves a Schreier Figure of Merit of 168.1 dB. The proposed modulator is also able to work with lower supply voltages down to 0.15 V with the same resolution and a lower power consumption despite of a lower bandwidth. These characteristics make this design very appealing in sensor interfaces powered by energy harvesting sources.
An assessment of regulatory compliance and residents’ perceptions of the siting of telecommunication masts: Insights from a rapidly urbanising Ghanaian city

ABSTRACT This study assesses the level of compliance with the regulations that guide the siting of telecommunication masts in the Kumasi Metropolis. Adopting a comparative case study research approach, 83 respondents were interviewed. The results of the study showed that, there was a complete compliance with the height standard for masts; however, there was high level of non-compliance with regards to the safety zone of 20m. Also, the requirement for the telecommunication firms to ensure co-location of their masts has been violated in the study areas. In conclusion, the non-compliance with the regulations could undermine the quest to make Kumasi sustainable.