Miracle-dz/UniFAR-FTUs huggingface dataset:
Effect of Traditional Cooking and Sous Vide Heat Treatment, Cold Storage Time and Muscle on Physicochemical and Sensory Properties of Beef Meat

Consumers are avoiding the consumption of highly processed foods, aware of the negative effects of the additives or high temperatures used on the biological value of the food. This causes an interest in ways of minimal processing or low-temperature cooking procedures. However, to achieve the desired organoleptic quality, it is necessary to know the relationship between the parameters of the treatments and the type of raw material. The purpose of this study was to investigate the complex effects of traditional cooking and sous vide heat treatment, cold storage time and muscle on the physicochemical and sensory properties of beef. The study material consisted of samples of musculus longissimus thoracis and musculus semitendinosus obtained from beef half-carcasses. The muscles were subjected to traditional cooking in water at 95 °C until the temperature inside the piece reached 65 °C and sous vide treatment at 65 °C for 2 h. The study was performed after 2 and 21 days of cold storage. Instrumental evaluation of texture parameters, color and sensory evaluation of meat was carried out. Meat stored for 21 days was characterized by more favorable TPA test (Texture Profile Analysis) results compared to meat evaluated 48 h post mortem. The study also showed positive effects of sous vide heat treatment on texture parameters and sensory properties (especially on tenderness and palatability), as well as differences in the formation of quality traits between muscles. Given the trends associated with energy-saving technologies, it is desirable to seek the optimal combination of temperature and time of fixation treatments at an acceptable level of quality. The use of low-temperature cooking for as little as 2 h, yields positive results in sensory evaluation of juiciness, tenderness, or palatability.
Opportunities and Hurdles to the Adoption and Enhanced Efficacy of Feed Additives towards Pronounced Mitigation of Enteric Methane Emissions from Ruminant Livestock

This paper analyzes the mitigation of enteric methane (CH4) emissions from ruminants with the use of feed additives inhibiting rumen methanogenesis to limit the global temperature increase to 1.5 °C. A mathematical simulation conducted herein predicted that pronounced inhibition of rumen methanogenesis with pure chemicals or bromoform-containing algae with an efficacy higher than that obtained in most studies can be important to limiting global temperature increase by 2050 to 1.5 °C but will likely need to be accompanied by improved production efficiency and other mitigation measures. Currently, the most important limitations to the adoption of antimethanogenic feed additives are increased feeding cost without a consistent return in production efficiency and achieving sustained delivery of inhibitors to grazing animals, especially in extensive systems. Economic incentives could be applied in some countries to favor adoption of inhibitors. Changes in rumen microbial and whole animal metabolism caused by inhibiting methanogenesis could potentially be used to make the methanogenesis inhibition intervention cost-effective, although research in this direction is unlikely to yield results in the short term. Future research directions to maximize the adoption and efficacy of inhibitors of methanogenesis are examined.
Search for an exotic S =-2, Q =-2 baryon resonance at a mass near 1862 MeV in quasireal photoproduction

A search for an exotic baryon resonance with S=-2, Q=-2 has been performed in quasireal photoproduction on a deuterium target through the decay channel {xi}{sup -}{pi}{sup -}{yields}{lambda}{pi}{sup -}{pi}{sup -}{yields}p{pi}{sup -}{pi}{sup -}{pi}{sup -}. No evidence for a previously reported {xi}{sup --}(1860) resonance is found in the {xi}{sup -}{pi}{sup -} invariant mass spectrum. An upper limit for the photoproduction cross section of 2.1 nb is found at the 90% confidence level. The photoproduction cross section for the {xi}{sup 0}(1530) is found to be between 9 and 24 nb.
Anti-de Sitter relativity

The relative geodesic motion on $(1+3)$-dimensional anti-de Sitter spacetimes is studied in terms of conserved quantities by adapting the Nachtmann boosting method created initially for the de Sitter spacetimes. In this approach the Lorentzian isometriy is derived, relating the coordinates of the local chart of a fixed observer with the coordinates of a mobile chart considered as the rest frame of a massive mobile object moving on a timelike anti-de Sitter geodesic. The transformation of the conserved quantities is also investigated, constructing thus a complete theory of the relative geodesic motion on anti-de Sitter spacetimes. Some applications are discussed among them the problems of twin paradox and Lorentz contraction are solved.
Assessing the Accuracy of Google Trends for Predicting Presidential Elections: The Case of Chile, 2006-2021

This article presents the results of reviewing the predictive capacity of Google Trends for national elections in Chile. The electoral results of the elections between Michelle Bachelet and Sebastián Piñera in 2006, Sebastián Piñera and Eduardo Frei in 2010, Michelle Bachelet and Evelyn Matthei in 2013, Sebastián Piñera and Alejandro Guillier in 2017, and Gabriel Boric and José Antonio Kast in 2021 were reviewed. The time series analyzed were organized on the basis of relative searches between the candidacies, assisted by R software, mainly with the gtrendsR and forecast libraries. With the series constructed, forecasts were made using the Auto Regressive Integrated Moving Average (ARIMA) technique to check the weight of one presidential option over the other. The ARIMA analyses were performed on 3 ways of organizing the data: the linear series, the series transformed by moving average, and the series transformed by Hodrick–Prescott. The results indicate that the method offers the optimal predictive ability.
Conservative Therapy of External Invasive Cervical Resorption with Adhesive Systems: A 6-Year Follow-Up Case Report and Literature Review

The diagnosis and treatment of external invasive cervical resorption (EICR) could be a challenging clinical situation even for the most experienced dentists. It is a fairly rare lesion and a poorly understood phenomenon, and its insidious and aggressive nature can lead to tooth loss. Even in the era of dental implants, trying to save a compromised tooth is imperative for any clinician. This report presents a case of an upper central incisor with a class II Heithersay EICR in which treatment was performed using a multidisciplinary approach and the defect was restored with resin composite. The surgery in which the defect was exposed and repaired was followed by an endodontic treatment and the placement of a fiber-reinforced post. In this case, the use of modern materials, such as resin composites, allowed not only the avoidance of tooth extraction but also the achievement of satisfactory aesthetic results. The 6-year follow-up demonstrated the success of therapy and the resolution of clinical symptoms. This case report highlights the importance of early detection of EICR and how composite resins could provide an effective and aesthetic restauration of the defect, which favors the health of the surrounding gingival tissue.
Pulsar Navigation in the Solar System

The X-ray Navigation and Autonomous position Verification (XNAV) is tested which use the Crab pulsar under the Space Test Program that use starlight refraction. It provide the way that the spacecraft could autonomously determine its position with respect to an inertial origin. Now we analysis the sensitivity of the exist instrument and the signal process that use radio pulsar navigation and discuss the integrated navigation which use radio pulsar, then give the different navigation mission analysis and design process basically which include the space, the airborne, the ship and the land of the planet or the lunar. Our analysis show that we will have the stability profile (signal-to-noise is 5 ) that use a 2 meters antenna observe some strong sources of radio pulsar in 36 minutes which based on the today’s technology. So the pulsar navigation can give the continu� DJ is in YunNan Astronomical Observatory, Email: djcosmic@gmail.com, and Scientific and application center of lunar and deep space exploration, NAOs, China. The content of this paper have applied the patent. † Manuscript received —; revised —. ous position in deep space, that means we can freedom fly successfully in the solar system use celestial navigation that include pulsar and traditional star sensor. It also can less or abolish the dependence to Global Navigation Satellite System (GNSS) which include GPS, GRONSS, Galileo and BeiDou et al.
Design and Implementation of Airway Response Teams to Improve the Practice of Emergency Airway Management

Emergency airway management (EAM) is a commonly performed procedure in the critical care setting. Despite clinical advances that help practitioners identify patients at risk for having a difficult airway, improved airway management tools, and algorithms that guide clinical decision-making, the practice of EAM is associated with significant morbidity and mortality. Evidence suggests that a dedicated airway response team (ART) can help mitigate the risks associated with EAM and provide a framework for airway management in acute settings. We review the risks and challenges related to EAM and describe strategies to improve patient care and outcomes via implementation of an ART.
Global surgery formula for the Casson-Walker invariant

This book presents a new result in 3-dimensional topology. It is well known that any closed oriented 3-manifold can be obtained by surgery on a framed link in "S"3. In "Global Surgery Formula for the Casson-Walker Invariant, " a function F of framed links in "S"3 is described, and it is proven that F consistently defines an invariant, lamda ("l"), of closed oriented 3-manifolds. "l" is then expressed in terms of previously known invariants of 3-manifolds. For integral homology spheres, "l" is the invariant introduced by Casson in 1985, which allowed him to solve old and famous questions in 3-dimensional topology. "l" becomes simpler as the first Betti number increases.As an explicit function of Alexander polynomials and surgery coefficients of framed links, the function F extends in a natural way to framed links in rational homology spheres. It is proven that F describes the variation of "l" under any surgery starting from a rational homology sphere. Thus F yields a global surgery formula for the Casson invariant.
Estrogen receptor 1 inhibits the progression of hepatocellular carcinoma via positively regulating lncRNA maternally expressed gene 3 under high glucose conditions

Background Long noncoding RNA (lncRNA) maternally expressed gene 3 (MEG3) is crucial in the association of diabetes mellitus (DM) and hepatocellular carcinoma (HCC), and estrogen receptor 1 (ESR1) plays an essential role in various cancers. However, the underlying regulatory effect of ESR1/lncRNA MEG3 on HCC with DM remains unclear. This study explored the regulatory effect of ESR1/lncRNA MEG3 on HCC cell progression. Methods Bioinformatics analysis was used to predict the promoter sequence of lncRNA MEG3 using UCSC (http://genome.ucsc.edu/), followed by luciferase reporter and RNA immunoprecipitation (RIP) assays to verify the specific combination between ESR1 and lncRNA MEG3 promoter. After cotransfection with ESR1, ESR1 siRNA or lncRNA MEG3 RNA, CCK-8, 5-ethynyl-2’-deoxyuridine (EdU) and colony formation assays were used to evaluate the cell proliferation capacity. Cell apoptosis was assessed using flow cytometry analysis. Next, wound healing and Transwell assays were conducted to examine cell invasiveness and migration. Quantitative real-time polymerase chain reaction (qRT-PCR) and western blot analysis were performed to quantify the expression of ESR1 or lncRNA MEG3. Results ESR1 might be the transcription factor (TF) of lncRNA MEG3, and ESR1 bound with lncRNA MEG3 promoter. Overexpression of ESR1 repressed the proliferation, migration and invasion of HepG2 cells, and promoted apoptosis of HepG2 cells under high glucose conditions. Silencing ESR1 decreased lncRNA MEG3 expression in HepG2 cells but enhanced proliferation, migration and invasion. Meanwhile, a rescue assay demonstrated that silencing lncRNA MEG3 reversed the inhibitory effect of ESR1 on HepG2 cell progression. Conclusions ESR1 inhibits HCC cell progression through positively regulating lncRNA MEG3, and the results provide a promising strategy for HCC management.
Clinical Features and Prognosis of Diffuse Midline Glioma: A Series of 24 Cases

Background Diffuse midline glioma (DMG) which occurs in midline structures and characterized by harboring K27M mutation in genes encoding the histone 3 protein is classified as World Health Organization (WHO) grade IV regardless of histological findings and has a poor prognosis. Nevertheless, because of its relatively rare incidence compared with other high-grade gliomas, a comprehensive description encompassing clinical features and genomic profiles of DMG is still lacking. Methods In this study, we analyzed data of 24 patients who were diagnosed as DMG which was confirmed by surgical specimens in both pediatric and adult patients. We described the clinical outcomes of patients with DMG and their genomic profiles through a retrospective analysis of 24 patients with DMG. Results The clinical characteristics of the 24 patients with DMG were analyzed. Ten patients (41%) underwent tumor resection and 14 patients (59%) underwent tumor biopsy. The median overall survival was 10.4 months (95% confidence interval [CI], 8.4 to 12.5) and progression free survival was 3.9 months (95% CI, 2.6 to 5.2). Fifteen patients (62%) were accompanied by hydrocephalus. None of the patient, tumor, or treatment factors had any significant associated with survival. In both immunohistochemistry staining (n=24) and targeted next generation sequencing (n=15), TP53 mutation was the most common genetic mutation (25% and 46%, respectively) found in the patients except alterations in histone 3 protein. Conclusion Although surgical treatment of patient with DMG does not affect the overall survival prognosis, it can help improve the patient’s accompanying neurological symptoms in some limited cases. Hydrocephalus is often accompanied with DMG and treatment for hydrocephalus is often also required. Multidisciplinary therapeutic approach is needed.
Représentations lisses modulo l de GL m (D)

Let F be a non-Archimedean locally compact field of residue characteristic p, let D be a finite dimensional central division F-algebra and let R be an algebraically closed field of characteristic different from p. We classify all smooth irreducible representations of GL(m,D) with coefficients in R, in terms of multisegments, generalizing works by Zelevinski, Tadic and Vigneras. We prove that any irreducible R-representation of GL(m,D) has a unique supercuspidal support, and thus get two classifications: one by supercuspidal multisegments, classifying representations with a given supercuspidal support, and one by aperiodic multisegments, classifying representations with a given cuspidal support. These constructions are made in a purely local way, with a substantial use of type theory.
Model reduction by weighted Component Cost Analysis

Component Cost Analysis considers any given system driven by a white noise process as an interconnection of different components, and assigns a metric called 'component cost' to each component. These component costs measure the contribution of each component to a predefined quadratic cost function. A reduced-order model of the given system may be obtained by deleting those components that have the smallest component costs. The theory of Component Cost Analysis is extended to include finite-bandwidth colored noises. The results also apply when actuators have dynamics of their own. Closed-form analytical expressions of component costs are also derived for a mechanical system described by its modal data. This is very useful to compute the modal costs of very high order systems. A numerical example for MINIMAST system is presented.
Fe Kα and Hydrodynamic Loop Model Diagnostics for a Large Flare on II Pegasi

The observation by the Swift X-ray Telescope of the Fe Kα1, α2 doublet during a large flare on the RS CVn binary system II Peg represents one of only two firm detections to date of photospheric Fe Kα from a star other than our Sun. We present models of the Fe Kα equivalent widths reported in the literature for the II Peg observations and show that they are most probably due to fluorescence following inner shell photoionization of quasi-neutral Fe by the flare X-rays. Our models constrain the maximum height of flare the to 0.15R* assuming solar abundances for the photospheric material, and 0.1R* and 0.06R* assuming depleted photospheric abundances ([M/H] = –0.2 and –0.4, respectively). Accounting for an extended loop geometry has the effect of increasing the estimated flare heights by a factor of ~3. These predictions are consistent with those derived using results of flaring-loop models, which are also used to estimate the flaring loop properties and energetics. From loop models we estimate a flare loop height of 0.13R*, plasma density of ~4 × 1012 cm−3, and emitting volume of ~6 × 1030 cm3. Our estimates for the flare dimensions and density allow us to estimate the conductive energy losses to Econd ⩽ 2 × 1036 erg, consistent with upper limits previously obtained in the literature. Finally, we estimate the average energy output of this large flare to be ~1033 erg s−1, or 1/10th of the stellar bolometric luminosity.
A new iterative weighted norm minimization algorithm and its applications

A general class of linear inverse problems in which the solutions are sparse and localized is considered. The proposed algorithm is a nonparametric approach that finds sparse and localized solutions without prior information on the constraints. Each step of the iterative procedure consists in solving a weighted least squares problem wherein the weighting matrix is determined by the solution from the previous iteration. Some properties of the algorithm along with its applications to problems in direction of arrival and spectrum estimation are presented. <<ETX>>
All Moments of Discrete and Continuous Arithmetic Averages on Brownian Paths: A Closed Form

This note derives new expressions for the moments of the average of values taken by Wiener paths at an arbitrary number, N, of discrete times. The expressions are closed summations, which entail only the N-th powers of, and the successive differences between, the moments of the lognormal finite dimensional distribution of the process' values at the time of the first averaging. By passing to the limit of the average when the averaging frequency becomes continuous, known forms for the continuous average are generalized by a single expression.
Paternal preconceptional diet enriched with n-3 polyunsaturated fatty acids affects offspring brain function in mice

Recent studies demonstrate that paternal nutrition prior to conception may determine offspring development and health through epigenetic modification. This study aims to investigate the effects of paternal supplementation of n-3 polyunsaturated fatty acids (n-3 PUFAs) on the brain development and function, and associated gene imprinting in the offspring. Three to four-week-old male C57BL/6J mice (founder) were fed with an n-3 PUFA-deficient diet (n-3 D), and two n-3 PUFA supplementation diets – a normal n-3 PUFA content diet (n-3 N) and a high n-3 PUFA content diet (n-3 H) for 12 weeks. Then they were mated to 10-week-old virgin female C57BL/6J mice to generate the offspring. The results showed that paternal n-3 PUFA supplementation in preconception reduced the anxiety- and depressive-like behavior, and improved sociability, learning and memory in the offspring, along with increased synaptic number, upregulated expressions of neuron specific enolase, myelin basic protein, glial fibrillary acidic protein, brain-derived neurotrophic factor in the hippocampus and cerebral cortex, and altered expressions of genes associated with mitochondria biogenesis, fusion, fission and autophagy. Furthermore, with paternal n-3 PUFA supplementation, the expression of imprinted gene Snrpn was downregulated both in testes of the founder mice and their offspring, but upregulated in the cerebral cortex and hippocampus, with altered DNA methylation in its differentially methylated region. The data suggest that higher paternal intake of n-3 PUFAs in preconception may help to maintain optimal brain development and function in the offspring, and further raise the possibility of paternal nutritional intervention for mental health issues in subsequent generations.
Michel Henon's contributions to collisional stellar systems

The theory of star cluster dynamics was a major topic in H\'enon's early research career. Here we summarise his contributions under three headings: (i) the Monte Carlo method, (ii) homological evolution of star clusters, and (iii) escape from star clusters. In each case we also trace some aspects of how H\'enon's contributions have been developed or applied in subsequent decades up to the present. We also propose that H\'enon's work be commemorated by adopting the names "H\'enon units" and "H\'enon's Principle".
Crystalline color superconductors

Inhomogeneous superconductors and inhomogeneous superfluids appear in a variety of contexts including quark matter at extreme densities, fermionic systems of cold atoms, type-II cuprates, and organic superconductors. In the present review the focus is on properties of quark matter at high baryonic density, which may exist in the interior of compact stars. The conditions realized in these stellar objects tend to disfavor standard symmetric BCS pairing and may favor an inhomogeneous color superconducting phase. The properties of inhomogeneous color superconductors are discussed in detail and in particular of crystalline color superconductors. The possible astrophysical signatures associated with the presence of crystalline color superconducting phases within the core of compact stars are also reviewed.
Changes in Serum Alkaline Phosphatase, Calcium, and Parathyroid Hormone with Different Doses of Iodine Therapy:.

Background: Despite the benefits of radioactive iodine (RAI) therapy as an adjunctive treatment for thyroid cancer, it can be associated with several side effects. The main purpose of this study was to determine the changes in serum alkaline phosphatase (ALP), calcium (Ca), and parathyroid hormone (PTH) at different doses of RAI therapy among patients who were referred to the nuclear medicine department of Namazi Hospital, Shiraz. Materials and Methods: This cross-sectional study was conducted on 60 patients with papillary thyroid cancer who underwent RAI therapy at different doses of 100, 150, and 200 mCi. The ALP, Ca, and PTH levels of patients were measured before and 60 days after RAI therapy. Results: Our study revealed that RAI therapy at all doses significantly increased ALP level in comparison with baseline amounts (P≤0.05). However, changes in PTH and Ca levels were not significant among patients who received different doses of RAI (P˃0.05). Conclusion: RAI therapy could affect important hormones and enzymes such as ALP and PTH. This issue can be considered in diagnostic and therapeutic prescriptions of RAI for the treatment of thyroid cancer. [GMJ.2022;11:e2397].