Miracle-dz/UniFAR-FTUs huggingface dataset:
SNR in active receiving antenna used as an element of phased antenna array for GURT radio telescope

Giant Ukrainian Radio Telescope (GURT) is a low-frequency one with active phased antenna array, which is being built in Ukraine in addition to the existing UTR-2 radio telescope. In this paper we consider the signal-to-noise ratio in active antenna, which is used as an element of GURT radio telescope antenna array. The sensitivity of the element mainly determines the sensitivity of not only the entire antenna array, but of the whole radio telescope, too. The research technique and the results of numerical calculations are given.
Motion mechanism and thrust characteristics of amphibious robots with long fin fluctuation for propulsion on hard level ground

This paper presents the principle of motion, mechanical modeling and key characteristics of the propulsive force of a new flexible-fin traveling wave propulsion mechanism used in an amphibious robot. Firstly, the form of motion and the basic propulsion principle of traveling wave propulsion of flexible fins on the ground are described. During fluctuation of the flexible fins, the relative motion between the outermost contact line on the fin surface and the ground generates the propulsive force of forward motion and the lateral force along the fin surface. Based on the laws of flexible-fin fluctuation kinematics and the basic principles of friction mechanics, the propulsion mechanics model of flexible fins during traveling wave propulsion on the ground is established. By numerically solving the propulsive force equation, the relationship between the propulsive force of the flexible fin and the motion parameters of the fin surface can be obtained. Numerical calculations combined with the results of experimental tests reveal that the flexible-fin propulsive force shows periodic variations within one fluctuation period of the fin surface, and the variation period is related to the number of waves present on the fin surface. The wavenumber on the fin surface has a large impact on the fluctuation amplitude of the propulsive force. In the range of 1.6–1.9 waves on the fin surface, the average propulsive force is the most ideal, while in the range of fin-surface inclinations less than 50° and fluctuation amplitudes greater than 30°, the propulsive force of the flexible fin is the ideal parameter range. This research provides theoretical support for the design of a flexible-fin traveling wave propulsion mechanism.
The impact of pediatric early warning score and rapid response algorithm training and implementation on interprofessional collaboration in a resource-limited setting

Introduction Improved teamwork and communication have been associated with improved quality of care. Early Warning Scores (EWS) and rapid response algorithms are a way of identifying deteriorating patients and providing a common framework for communication and response between physicians and nurses. The impact of EWS implementation on interprofessional collaboration (IPC) has been minimally studied, especially in resource-limited settings. Methods The study took place in the Pediatric Department of the main academic referral hospital in Rwanda between April 2019 and January 2020. Pediatric nurses and residents were trained on the use of the Pediatric Warning Score for Resource-Limited Settings (PEWS-RL) and a rapid response algorithm. Training included vital sign collection, PEWS-RL calculation, IPC and rapid response algorithm implementation. Prior to training, participants completed surveys on IPC with Likert scale responses (from “strongly disagree” to “strongly agree”). Follow-up surveys were then administered nine months later and also included an open-response question on the impact of the PEWS-RL implementation on IPC. Results Sixty-five (96%) nurses were trained and completed the pre-survey and thirty-seven (54%) of the trained nurses completed the post-survey. Twenty-two (59%) pediatric residents were trained in the workshop and completed the pre-survey and twenty-four physicians (4 pediatricians (40%) and 20 pediatric residents (53%)) completed the post-implementation survey. There was a statistically significant increase in the percent of nurses indicating strong agreement across all domains of communication and collaboration from the pre- to the post-survey. Although the percent of physicians indicating strong agreement increased in the post-survey for all items, only the “share information” item was statistically significant. Conclusion Training and implementation of a PEWS-RL and a rapid response algorithm at a tertiary hospital in Rwanda resulted in significant improvement of nurse and physician ratings of IPC nine months later.
Indoor air quality measurements in Hungarian residential buildings

Indoor air quality is a major part of indoor environmental quality and plays an important role in creating sustainable and healthy indoor environments. Well-being, health and comfort are affected by indoor air quality. The measurements that are introduced in this research paper were used to record the results of three different residential interiors. These data are a part of a larger scale research project that included the evaluation of residential buildings, offices, university interiors and for instance nurseries. The reason behind conducting the measurements in these interiors was that in all of the examples inadequate indoor air quality and therefore human discomfort, illness and also building failure occurred. In this paper the theoretical background of the research and the measurement of indoor air quality (indoor air temperature, relative humidity level and carbon dioxide level) will be introduced. The poor indoor air quality in these buildings is a result of a complex system. The thermal bridges .
Tensor Recovery With Weighted Tensor Average Rank

In this article, a curious phenomenon in the tensor recovery algorithm is considered: can the same recovered results be obtained when the observation tensors in the algorithm are transposed in different ways? If not, it is reasonable to imagine that some information within the data will be lost for the case of observation tensors under certain transpose operators. To solve this problem, a new tensor rank called weighted tensor average rank (WTAR) is proposed to learn the relationship between different resulting tensors by performing a series of transpose operators on an observation tensor. WTAR is applied to three-order tensor robust principal component analysis (TRPCA) to investigate its effectiveness. Meanwhile, to balance the effectiveness and solvability of the resulting model, a generalized model that involves the convex surrogate and a series of nonconvex surrogates are studied, and the corresponding worst case error bounds of the recovered tensor is given. Besides, a generalized tensor singular value thresholding (GTSVT) method and a generalized optimization algorithm based on GTSVT are proposed to solve the generalized model effectively. The experimental results indicate that the proposed method is effective.
Epithelial cell attachment and adhesion protein expression on novel in sol TiO2 coated zirconia and titanium alloy surfaces

Abstract An adequate mucosal attachment is important when it comes to preventing peri‐implant inflammation. The aim of this study was to compare epithelial cell adhesion and adhesion protein expression on in sol TiO2‐coated and non‐coated zirconia and titanium alloy surfaces. Fifty‐six zirconia and titanium discs were cut, and half of them were coated with bioactive TiO2‐coating. To study the epithelial cell attachment, human gingival keratinocytes were cultivated on discs for 1, 3, 6, and 24 h. The cell proliferation was detected by cultivating cells for 1, 3, and 7 days. In addition, the levels of adhesion proteins laminin y2, integrin α6, β4, vinculin, and paxillin were detected with Western Blot method. Furthermore, high‐resolution imaging of the actin cytoskeleton and focal adhesion proteins was established. Longer‐term cell culture (1–7 days) revealed higher cell numbers on the coated zirconia and titanium discs compared to non‐coated discs. The difference was statistically significant (p < .05) after 24 h on coated zirconia and after 3 and 7 days on coated titanium discs compared to non‐coated discs. Clear induction in the protein levels of laminin y2 and integrin α6 were detected on both coated samples, meanwhile integrin β4 were clearly induced on coated titanium alloy. The microscope evaluation showed significantly increased cell spreading on the coated discs. According to this study, the in sol induced TiO2‐coating increases keratinocyte attachment and the expression of adhesion proteins on coated zirconia and titanium in vitro. Consequently, the coating has potential to enhance the mucosal attachment on implant surfaces.
Centroidal Clustering of Noisy Observations by Using th Power Distortion Measures

We consider the problem of clustering a dataset through multiple noisy observations of its members. The goal is to obtain a clustering that is as faithful to the clustering of the original dataset as possible. We propose a centroidal approach whose distortion measure is the sum of <inline-formula> <tex-math notation="LaTeX">$r$ </tex-math></inline-formula>th powers of the distances between the cluster center and the noisy observations. For <inline-formula> <tex-math notation="LaTeX">$r=2$ </tex-math></inline-formula>, our scheme boils down to the well-known approach of clustering the average of noisy samples. First, we provide a mathematical analysis of our clustering scheme. In particular, we find formulas for the average distortion and the spatial distribution of the cluster centers in the asymptotic regime where the number of centers is large. We then provide an algorithm to numerically optimize the cluster centers in the finite regime. We extend our method to automatically assign weights to noisy observations. Finally, we show that for various practical noise models, with a suitable choice of <inline-formula> <tex-math notation="LaTeX">$r$ </tex-math></inline-formula>, our algorithms can outperform several other existing techniques over various datasets.
Limits of exponential models on a lattice

The term “Algebraic Statistics” (AS) was introduced in Pistone et al. (2001) to denote the use in Statistics of mathematical technologies taken from Computational Commutative Algebra (CCA). The subject, started as early as 1993 in a preprint of the seminal paper Diaconis and Sturmfels (1998), is currently under intensive development; the best description of the current state of the art is obtained by looking at the papers and discussion presented in the specialized workshops: GrostatVI3, Menton Fr 2003, Computational Algebraic Statistics4, AIM Palo Alto Ca 2003, Computational Algebra for Algebraic Geometry and Statistics5, Torino It 2004. We cannot include in this short note an extensive bibliography. A very active area of development consists of the exploration of multiple application of algebraic computations to graphical models. The present paper illustrate the matter through a specific example, the 4-cycle as described in Lauritzen (1996). Two of the results below are published here, in short form, for the first time. Preliminary versions were published in Rapallo (2003) and Pistone and Wynn (2003). related results with full proofs are in Rapallo (2004). The present research is joint work with Fabio Rapallo and Henry P. Wynn. At the Conference time, all relevant computer listings and results will be posted on the Author’s web-site6.
Glucose Homeostasis and the Burnt-Out Diabetes Phenomenon in Kidney Disease

Chronic kidney disease (CKD) is among the most prevalent and dire complications of diabetes mellitus in adults across the world. Diabetes substantially contributes to the burden of kidney disease, such that one third to one half of CKD in the United States and many other countries is attributable to diabetic kidney disease (DKD). As DKD progresses to end-stage renal disease (ESRD), patients are at heightened risk for atypical glycemic complications, including the development of burnt-out diabetes, manifested by hypoglycemic bouts and poor outcomes. Furthermore, even in the absence of diabetes, hypoglycemia is a frequent occurrence in CKD patients that may contribute to their high burden of cardiovascular disease and death. Extrapolation of data from clinical trials in high-cardiovascular-risk populations and observational studies in patients with non−dialysis-dependent (NDD) CKD and ESRD suggest that moderate glycemic targets defined by glycated hemoglobin levels of 6% to 8% and glucose levels of 100 to 150 mg/dL are associated with better survival in DKD patients. However, given the imprecision of glycated hemoglobin levels in kidney disease, further research is needed to determine the optimal glycemic metric and target in diabetic NDD-CKD and ESRD patients. Given their exceedingly high cardiovascular morbidity and mortality, there is a compelling need for further investigation of how to optimally manage dysglycemia in the NDD-CKD and ESRD populations.
Liquid-Crystalline Phases of Cholesterol / Lipid Bilayers as Revealed by the Fluorescence of trans-Parinaric Acid

The presence of two liquid-crystalline phases, a and ,B, in mixed bilayers of dimyristoylphosphatidylcholine/ cholesterol was detected by the changes in the distribution of the fluorescence lifetimes of t-PnA, as analyzed by the Maximum Entropy Method. The formation of the liquid-ordered 13-phase, in the 30-400C temperature range as a function of cholesterol concentration (0-40 mol%), could be related quantitatively to the relative amplitude of a long lifetime component of the probe (10-14 ns). Based on this evidence, the phase behavior of mixtures of the unsaturated lipid palmitoyloleoylphosphatidylcholine and cholesterol was determined using the same technique, for cholesterol concentrations in the 0-50 mol% range, between 10 and 400C. It was found that two liquid-crystalline phases are also formed in this system, with physical properties reminiscent of the aand P-phases formed with saturated lipids. However, in this case it was determined that, for temperatures in the physiological range, the aand 1-phases coexist up to 40 mol% cholesterol. This finding may be of significant biological relevance, because it supports the long held notion that cholesterol is responsible for the lipid packing heterogeneity of several natural membranes rich in unsaturated lipid components.
Oral Immunotherapy With Human Secretory Immunoglobulin A Improves Survival in the Hamster Model of Clostridioides difficile Infection

1394 • jid 2021:224 (15 October) • BRIEF REPORT Received 19 November 2020; editorial decision 4 February 2021; accepted 8 February 2021; published online February 15, 2021. Correspondence: Michael R. Simon, MD, Secretory IgA, Inc, 1925 Scottwood Avenue, Ann Arbor, MI 48104 (mrsimonmd@sbcglobal.net). The Journal of Infectious Diseases 2021;224:1394–7 © The Author(s) 2021. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com. DOI: 10.1093/infdis/jiab087 Oral Immunotherapy With Human Secretory Immunoglobulin A Improves Survival in the Hamster Model of Clostridioides difficile Infection
Original Contribution Associations of Maternal GestationalWeight Gain andObesityWith the Timing of Pubertal Onset in Daughters

Early puberty is associatedwith adverse health outcomes, but little is known regarding early-life determinants influencing pubertal timing. We examined the associations between maternal gestational weight gain (GWG) and the timing of the onset of breast development (thelarche) and pubic hair development (pubarche) in a cohort of 2,070 girls born in a Kaiser PermanenteNorthernCalifornia facility between 2005and 2006. UsingWeibull regressionmodels accommodating interval censoring and adjusting for important confounders, we found that excessGWGwas associatedwith increased risk of early thelarche (hazard ratio (HR) = 1.50, 95% confidence interval (CI): 1.26, 1.78) and early pubarche (HR = 1.35, 95% CI: 1.10, 1.66). Inadequate GWG was associated with early thelarche (HR = 1.36, 95% CI: 1.08, 1.71). The associations between excess or inadequate GWG and risk of earlier thelarche were stronger if mothers were obese before or at the beginning of pregnancy (bodymass index≥30 kg bodyweight per m height squared) (HR = 2.01, 95%CI: 1.53, 2.63; HR = 2.08, 95% CI: 1.45, 2.98, respectively). Similar associations were found for pubarche outcome. Inclusion of girls’ prepubertal bodymass index slightly attenuated these associations, but they remained significant. Monitoring of maternal weight before and throughout pregnancymight help prevent early pubertal onset and subsequent negative health outcomes.
SPECIAL SERIES: LOCOREGIONAL MANAGEMENT OF BREAST CANCER

Patients fear lymphedema as an unpredictable daily reminder of breast cancer treatment. The medical community has assumed for years that the development of breast cancer–related lymphedema (BCRL) stemmed solely from the primary surgical extirpation of the axillary lymph nodes. However, contemporary data suggest that BCRL development is multifactorial, influenced by multimodality locoregional and systemic treatment strategies and perhaps by the individual patient’s ability to form collateral lymphatic pathways after injury, as well as potentially modifiable risk factors such as body mass index (BMI). Understanding the interaction between comprehensive locoregional treatment strategies and their collective impact on overall survival and long-term adverse effects such as BCRL is critical to providing patients individualized treatment recommendations. Herein, we review important factors for the development, diagnosis, prevention, and treatment of BCRL that should be considered when determining the contemporary locoregional management of breast cancer.
Receptors for extracellular heat shock proteins

Extracellular heat shock proteins (HSP) play important roles in cell signaling and immunity. Many of these effects are mediated by cell surface receptors expressed on a wide range of cell types. We have investigated the nature of such proteins by cloning candidate receptors into cells (CHO-K1) with the rare property of being null for HSP binding. Using this approach we have discovered that Hsp70 binds to a least two classes of receptor: c-type lectin receptors (CLR) and scavenger receptors (SR). However the nature of the receptor-ligand interactions is not yet clear. Hsp70 can bind to LOX-1 (a member of both the CLR and SR), with the c-type lectin binding domain (CTLD) as well as the SR family members SREC-I and FEEL-1/CLEVER-1/STABILIN-1, which by contrast have arrays of EGF-like repeats in their extracellular domains. In this chapter we discuss (1) methods for determining HSP receptors, (2) approaches to study of individual receptors in cells that contain multiple such receptors and (3) methods for investigating HSP receptor function in vivo.
Phosphatidylethanol (PEth) Levels in Post-Partum Women and Their Newborns in Uruguay and Brazil

Background: There is increasing interest in the development of newborn screening tests to identify children at risk of fetal alcohol spectrum disorder (FASD) in order to provide these children with early intervention. Phosphatidylethanol (PEth) has emerged as a potential universal newborn screening candidate. Correspondence: Michael Fleming, MD, Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Abbott Hall, Room 1320, 710 North Lakeshore Drive, Chicago Il 60611, 608-213-1128, mfleming@northwestern.edu. HHS Public Access Author manuscript Alcohol Clin Exp Res. Author manuscript; available in PMC 2021 June 01. Published in final edited form as: Alcohol Clin Exp Res. 2020 June ; 44(6): 1292–1299. doi:10.1111/acer.14339. A uhor M anscript
Surface Characterization of Virulent Treponema pallidum

Characterization of the surface of Treponema pallidum was accomplished by ['25I]lactoperoxidase-catalyzed iodination of intact organisms and sensitive ra-dioimmunoprecipitation and gel electrophoresis technology. At least 11 outer membrane proteins with molecular weights ranging from 89,000 (89K) to 20K were identified, and all elicited high titers of antibody in experimentally infected rabbits. Proteins of 89.5K, 29.5K, and 25.5K previously implicated as ligands involved in attachment (J. B. Baseman and E. C. Hayes, J. Exp. Med. 151:573-586, 1980) were found to reside on the treponemal surface. Low levels of the 89.5K treponemal protein were released by high salt concentrations, whereas the remaining comigrating material was neither radioiodinated nor released with selec- tive detergents. Other lower-molecular-weight (60K, 45K, and 30K) surface proteins were extracted with octyl glucoside detergent, suggesting their hydrophobic interaction with the external membrane. The molecular organization of surface proteins was studied by employing the cross-linker dithiobis(succinimidyl)-propionate, and data suggested the presence of a highly fluid envelope resulting in random collisions by the surface proteins. The biological function of the treponemal outer envelope proteins was evaluated using, as the indicator system, adherence of T. pallidum to monolayer cultures of eucaryotic cells. Trypsin treatment of motile, freshly harvested organisms decreased the extent of surface parasitism to normal rabbit testicular cells, reinforcing the idea of the proteinaceous nature and role of treponemal ligands for attachment. Other data supported functional
Identification and Characterization of a 47 Base Pair Activity- Dependent Enhancer of the Rat Nicotinic Acetylcholine Receptor d-Subunit Promoter

Nicotinic acetylcholine receptor (nAChR) genes are regulated by muscle electrical activity. E-box sequences found in their promoters are necessary for this regulation. However, many muscle genes contain E-boxes, yet are not regulated by muscle depolarization. This suggests that other elements are necessary, perhaps working in conjunction with E-boxes, to confer depolarization-dependent control onto promoter activity. We have used direct DNA injection into muscle as an in vivo assay to identify and characterize these additional elements. Mutagenesis and expression assays identified multiple elements within the first 81 base pairs (bp) of the nAChR d-subunit promoter that contribute to its regulation by muscle electrical activity. Within this 81 bp sequence, two regions of DNA were identified that were capable of conferring activity-dependent regulation onto a heterologous promoter. The stronger of these two putative enhancers was characterized further. It is a 47 bp sequence that contains an E-box along with sequences similar to the SV40 core enhancer and an SP1 site. Site-directed mutagenesis identified residues within each of these sequences that were necessary for enhancer activity. Furthermore, methylation interference DNA footprinting assays showed increased nuclear protein binding to sequences within both these enhancers after muscle denervation, and this pattern of binding was very similar to that observed with nuclear protein isolated from myotube extracts. These latter results suggest that similar mechanisms may mediate increased nAChR expression during muscle development and after muscle denervation.