Miracle-dz/UniFAR-FTUs huggingface dataset:
Near infrared (NIR) hyperspectral imaging for evaluation of whole maize kernels: chemometrics for exploration and classification

The use of near infrared (NIR) hyperspectral imaging and hyperspectral image analysis for distinguishing between whole maize kernels of varying degrees of hardness and fungal infected and non-infected kernels have been investigated. Near infrared hyperspectral images of whole maize kernels of varying degrees of hardness were acquired using a Spectral Dimensions MatrixNIR camera with a spectral range of 960-1662 nm as well as a sisuChema SWIR (short wave infrared) hyperspectral pushbroom imaging system with a spectral range of 1000-2498 nm. Exploratory principal component analysis (PCA) on absorbance images was used to remove background, bad pixels and shading. On the cleaned images, PCA could be used effectively to find histological classes including glassy (hard) and floury (soft) endosperm. PCA illustrated a distinct difference between floury and glassy endosperm along principal component (PC) three. Interpreting the PC loading line plots important absorbance peaks responsible for the variation were 1215, 1395 and 1450 nm, associated with starch and moisture for both MatrixNIR images (12 and 24 kernels). The loading line plots for the sisuChema (24 kernels) illustrated peaks of importance at the aforementioned wavelengths as well as 1695, 1900 and 1940 nm, also associated with starch and moisture. Partial least squares-discriminant analysis (PLS-DA) was applied as a means to predict whether the different endosperm types observed, were glassy or floury. For the MatrixNIR image (12 kernels), the PLS-DA model exhibited a classification rate of up to 99% for the discrimination of both floury and glassy endosperm. The PLS-DA model for the second MatrixNIR image (24 kernels) yielded a classification rate of 82% for the discrimination of glassy and 73% for floury endosperm. The sisuChema image (24 kernels) yielded a classification rate of 95% for the discrimination of floury and 92% for glassy endosperm. The fungal infected and sound whole maize kernels were imaged using the same instruments. Background, bad pixels and shading were removed by applying PCA on absorbance images. On the cleaned images, PCA could be used effectively to find the infected regions, pedicle as well as non-infected regions. A distinct difference between infected and sound kernels was illustrated along PC1. Interpreting the PC loading line plots showed important absorbance peaks responsible for the variation and predominantly associated with starch and moisture: 1215, 1450, 1480, 1690, 1940 and 2136 nm for both MatrixNIR images (15 and 21 kernels). The MatrixNIR image (15 kernels) exhibited a PLS-DA classification rate of up to 96.1% for the discrimination of infected kernels and the sisuChema had a classification rate of 99% for the same region of interest. The
Efficacy of mFOLFOX6 plus bevacizumab regimen in advanced colorectal cancer after deep hyperthermia: a single-center retrospective study

Background This study aimed to explore the clinical efficacy and safety of a modified FOLFOX6 (oxaliplatin + leucovorin + 5-fluorouracil) plus bevacizumab regimen after deep hyperthermia in advanced colorectal cancer. Methods A total of 80 colorectal cancer patients treated at our hospital were selected as research subjects. According to the random number table method, patients were divided into a control group (mFOLFOX6 plus bevacizumab) and a combination group (mFOLFOX6 plus bevacizumab after deep hyperthermia treatment), with 40 patients in each group. After six cycles of treatment, the objective response rate (ORR), disease control rate (DCR), levels of serum tumor markers carcinoembryonic antigen (CEA), vascular epidermal growth factor (VEGF), Karnofsky performance status (KPS) scores, and the occurrence of adverse events were compared between the two groups. Results After six cycles of treatment, the ORR in the combination group was higher than that in the control group, but the difference was not statistically significant (P>0.05). The DCR in the combination group was significantly higher than that in the control group (P<0.05). The serum CEA levels in the control and combination groups after treatment were significantly lower than those before treatment, and the serum CEA and VEGF levels in the combination group were significantly lower than those in the control group (all P<0.001). The KPS scores in both groups after treatment were higher than those before treatment, and the KPS scores in the combination group after treatment were significantly higher than those in the control group (all P<0.001). The incidence of fatigue and pain in the combination group was significantly lower than that in the control group (P<0.05). Conclusion mFOLFOX6 plus bevacizumab after deep hyperthermia is effective in advanced colorectal cancer patients, which can effectively improve their quality of life, and the adverse events are controllable and tolerable. A randomized or prospective trial will be required to further prove these data and explore its potentiality, especially if compared to conventional treatment.
Unveiling the profound advantages of total neoadjuvant therapy in rectal cancer: a trailblazing exploration

The standard treatments for locally advanced rectal cancer typically involved neoadjuvant therapy with either short-course radiation or long-course chemoradiation, followed by radical surgery and adjuvant chemotherapy. While the advancement of surgical techniques and the adoption of multimodal therapy have greatly contributed to reducing local failure, there has been limited improvement in overall survival, primarily due to the stagnation in systemic failure. In response to this challenge, a new strategy known as total neoadjuvant therapy (TNT) has emerged, involving the administration of both full-dose chemotherapy and radiation before surgery. It has shown promise in reducing systemic failure, enhancing tumor regression, and improving treatment adherence, ushering in a new era in the standard treatment of locally advanced rectal cancer. This review aims to summarize the evolution of multimodal treatments for locally advanced rectal cancer, ultimately converging into the current TNT strategy, and provides an assessment of the benefits and limitations of TNT based on available evidence, serving as a foundation for selecting the best treatment option.
A GIS-BASED ANALYSIS OF THE LIKELIHOOD OF ADOPTION OF SOME MULTI-PURPOSE TREE SPECIES IN EAST AFRICA

ABSTRACT The Multi-purpose Tree (MPT) species have the ability to fit into the farming systems of the East African region where low agricultural productivity, widespread land degradation and hence a diminishing capacity to support the growing human and livestock population are major problems. GIS has been used to develop a spatial representation of the recommendation domains of five MPT species (Calliandra calothyrsus, Sesbania sesban, Leucaena diversifolia, L. pallida and Chamaecytisus palmensis) in Ethiopia, Kenya and Uganda. The recommendation domains were selected based on climatic, edaphic and topographic factors. The likelihood of adoption, within the agro-ecologically suitable areas for each species, has been defined by weighing and combining three factors: the type of land cover/land use, the human and cattle population densities.
To Effectively Address Complex Healthcare Problems, Continuing Professional Development Must Evolve

Abstract Continuing professional development aims to provide health professionals with the knowledge, skills, and competencies needed to improve care. Physicians and other clinicians increasingly practice within complex health care delivery organizations aiming to improve the care of populations of patients with multiple problems and differing needs. These organizations are composed of local units in different departments and venues; these teams and the patients they care for change over time. Improving outcomes within constantly changing complex organizations delivering population care takes time and persistence. It takes time to equip critical masses of clinicians and other personnel with knowledge and skills to effect change. Although some changes might be simple, those involving new workflows require implementation support. Not all change will be smooth; individuals need opportunities to learn from and adjust their early intervention efforts, measure effectiveness of change, and sustain successful practices. Longitudinal support is necessary to affect change over complex organizations. This essay proposes that to be more supportive and valuable to health care delivery organizations, continuing professional development needs to intentionally participate in longitudinal, collaborative, context-specific, team-based interventions. An expanded menu of evaluation approaches will better describe the role of continuing professional development in helping health care professionals and organizations address increasingly complex health care delivery problems and improve patient and population outcomes. Selected concepts to achieve these ends are introduced at a high level in this article. Readers are invited to explore concepts that resonate with their current situation in further detail.
This item is the archived peer-reviewed author-version of: Extensive charge reduction and dissociation of intact protein complexes following electron transfer on a quadrupole-ion mobility-time-of-flight MS

Non-dissociative charge reduction, typically considered an unwanted side reaction in electron transfer dissociation (ETD) experiments, can be enhanced significantly in order to reduce the charge state of intact protein complexes to as low as 1+ on a commercially available Q-IM-TOF instrument. This allows for the detection of large complexes beyond 100,000 m/z , while at the same time generating top-down ETD fragments which provide sequence information from surface-exposed parts of the folded structure. Optimization of the supplemental activation has proven crucial in these experiments and the charge-reduced species are most likely the product of both proton transfer (PTR) and non-dissociative electron transfer (ETnoD) reactions which occur prior to the ion mobility cell. Applications of this approach range from deconvolution of complex spectra to the manipulation of charge states of gas-phase ions.
Landfill site characterisation at Kham Bon village, Muang district, Khon Kaen province, NE Thailand

The aim of the study is to characterise the Kham Bon landfill site. Hydrogeological and geochemical surveys were conducted and four boreholes were drilled. The hydraulic properties of the aquifer were tested, and soil, surface water and groundwater samples were collected at various times in the year. The physical and chemical properties of the samples, especially heavy metals, were analysed. The results indicated that Cd, Cr, Pb, Cu and Zn occurred in significant concentrations in the soil. The concentrations of Pb, Fe and Mn are high in surface water and groundwater. Moreover, the groundwater chemistry of the shallow aquifer was characterised by high concentrations of some ions. The major factors controlling leachate production and migration in this area are the seasonal variations in precipitation, the site topography, which controls the runoff patterns, and the soil type, which affects infiltration and solute transport to the water table.
Issues in Information Systems

As more and more organizations’ financial transaction systems are information system based, perpetrators of financial crimes must often circumvent accounting information system internal controls to commit their crimes. The ability of internal audit functions to audit information system internal control implementation and execution is receiving increased emphasis both in education and practice. This paper examines whether computer crime is more difficult to detect and investigate than traditional schemes. The study presents a detailed analysis of the ways the computer was used to assist the perpetrator in 72 cases. The study also examines differences between the computer fraud cases and 99 fraud cases without computer involvement. The fraud information was collected through the use of an electronic survey voluntarily completed by members of a professional accounting association in south Texas. The survey consisted of 73 questions that provided detailed information about the victim organization, perpetrators, fraud schemes, detection, investigation, and outcomes. The results of the study will be useful to accounting information systems professionals, fraud examiners, and auditors.
Effectiveness of Sonification of Ketumbar Tip (Coriandrum Sativum L.) for Diabetes Melites Complications on the Gynels with Manly Wistar Rats (Rattus Norvegicus) as Aloksan Induced Coal Animals

The most common microvascular complication is diabetic nephropathy. Coriander is traditionally used as a stimulant, carminative, anticonvulsant, diuretic and antirheumatic, antiemetic and has potential as an antioxidant. Thus, the authors were interested in exploring the effectiveness of coriander seed sonification (Coriandrum sativum L.) on complications of diabetes mellitus in alloxan-induced male rats as experimental animals, especially on kidney micro-vascularization. This study was an experimental study. In this study, sonification of coriander seeds was carried out using a sonicator. All rats in this study were induced by injection of 5% alloxan, then grouped into 5 different groups including: control (Na-CMC), standard (metformin), coriander seed sonification 200 mg/kgBW, 400 mg/kgBW, and 800 mg/kgBW. The measured parameters in this study were GFR and uACR. The results revealed that the coriander seed sonification in this study significantly increased the GFR value and reduced uACR in line with the increase in the administered dose of coriander sonification (p value < 0.05). Hence, it can be concluded that coriander seed sonification has a protective effect against kidney damage due to diabetes.
Issues in Information Systems

The term Artificial Intelligence (AI) has been used frequently in the media and in advertisements in recent years. Yet, few can offer a clear and concise definition of the term “AI. ” This lack of a definition complicates the communication and understanding among entities that focus on the collaboration, use, and application of AI. Further complicating the landscape is the fact that advances in technology have altered the perception of AI, and consequently, the ways in which they are defined. The goal of this paper is to derive a definition that capture the current collective scientific, rather than the societal or media-based definition of the discipline (and its subcategories), map this definition to emerging areas in AI such as AIoT, and determine how well this mapping translates to an applied curriculum at the highest ranked schools. Specifically, are we adequately defining AI within the confines of how it is currently applied, and how we aspire to apply it? Are college degree programs preparing students to make contributions to this field, in terms of the application and advancement of AI?
Heavy Metals (Cd, Cu and As) Accumulation by Aquatic Plant along with Gomti River, Lucknow (U. P.)

The aquatic plants have a great importance to the removal of heavy metals from the contaminated river water. In this study the heavy metals (Cd, Cu and As) were evaluated in aquatic plants like Ranunculus sceleratus, Hydrilla virticillata, Botumusumbelatus and Sagittaria japonica collected from the 15 sites along with Gomti river, Lucknow (U. P.), Heavy metals enters into the river through the discharge of domestic sewage, industrial effluents, municipal waste water etc., The concentration of Cu was found maximum followed by Cd and least was As for all selected plants at all sites. The highest accumulation of Arsenic, Cadmium and Copper was found in Hydrilla virticillata (0.172±0.005 g g−1 DW), Sagittaria japonica(1.62±0.02 g g−1 DW) and Botumus umbelatus (2.08±0.07 g g−1 DW) respectively. However, the lowest concentration of all these heavy metals was observed in Ranunculus scleratus sp. The results of this study to give the information in relation to aquatic plants growing in polluted water, which accumulates heavy metals. These findings provide are an opportunity for the removal of toxic heavy metals from the use of aquatic plants in phytoremediation and treating water bodies.
Mineralogy and petrography of amoeboid olivine aggregates from the reduced CV3 chondrites Efremovka, Leoville and Vigarano: Products of nebular condensation, accretion and annealing

Abstract— Amoeboid olivine aggregates (AOAs) from the reduced CV chondrites Efremovka, Leoville and Vigarano are irregularly‐shaped objects, up to 5 mm in size, composed of forsteritic olivine (Fa<10) and a refractory, Ca, Al‐rich component. The AOAs are depleted in moderately volatile elements (Mn, Cr, Na, K), Fe, Ni‐metal and sulfides and contain no low‐Ca pyroxene. The refractory component consists of fine‐grained calcium‐aluminum‐rich inclusions (CAIs) composed of Al‐diopside, anorthite (An100), and magnesium‐rich spinel (∼1 wt% FeO) or fine‐grained intergrowths of these minerals; secondary nepheline and sodalite are very minor. This indicates that AOAs from the reduced CV chondrites are more pristine than those from the oxidized CV chondrites Allende and Mokoia. Although AOAs from the reduced CV chondrites show evidence for high‐temperature nebular annealing (e.g., forsterite grain boundaries form 120° triple junctions) and possibly a minor degree of melting of Al‐diopside‐anorthite materials, none of the AOAs studied appear to have experienced extensive (>50%) melting. We infer that AOAs are aggregates of high‐temperature nebular condensates, which formed in CAI‐forming regions, and that they were absent from chondrule‐forming regions at the time of chondrule formation. The absence of low‐Ca pyroxene and depletion in moderately volatile elements (Mn, Cr, Na, K) suggest that AOAs were either removed from CAI‐forming regions prior to condensation of these elements and low‐Ca pyroxene or gas‐solid condensation of low‐Ca‐pyroxene was kinetically inhibited.
Glacier crevasses: Observations, models, and mass balance implications

We review the findings of approximately 60 years of in situ and remote sensing studies of glacier crevasses, as well as the three broad classes of numerical models now employed to simulate crevasse fracture. The relatively new insight that mixed‐mode fracture in local stress equilibrium, rather than downstream advection alone, can introduce nontrivial curvature to crevasse geometry may merit the reinterpretation of some key historical observation studies. In the past three decades, there have been tremendous advances in the spatial resolution of satellite imagery, as well as fully automated algorithms capable of tracking crevasse displacements between repeat images. Despite considerable advances in developing fully transient three‐dimensional ice flow models over the past two decades, both the zero stress and linear elastic fracture mechanics crevasse models have remained fundamentally unchanged over this time. In the past decade, however, multidimensional and transient formulations of the continuum damage mechanics approach to simulating ice fracture have emerged. The combination of employing damage mechanics to represent slow upstream deterioration of ice strength and fracture mechanics to represent rapid failure at downstream termini holds promise for implementation in large‐scale ice sheet models. Finally, given the broad interest in the sea level rise implications of recent and future cryospheric change, we provide a synthesis of 10 mechanisms by which crevasses can influence glacier mass balance.
Characters of transport variations at the source and adjacent area of Kuroshio

Based on the long series of current velocity data from the new version of SODA reanalysis,and data of temperature and salinity on 137°E section,the transport on 4 main sections of the source and adjacent areas of Kuroshio were calculated.And the annual cycle and long-term variations were analyzed.The results indicate that the transport of the main Kuroshio sections have strong seasonal and striking inter-annual and inter-decadal variations.The correlation analysis shows that there were strong independences among the variations of the transport in main sections of Kuroshio.Among them the short climate changes are likely related to the tropical Pacific inter-annual variation,while the inter-decadal variation could be possibly associated with the North Pacific inter-decadal variations and subtropical meso-scale eddy.
Detection of natural oil seeps signature from SST and ATI in South Yellow Sea combining ASTER and MODIS data

Daytime Advanced Spaceborne Thermal Emission and reflection Radiometer (ASTER) data and the consequent nighttime Moderate Resolution Imaging Spectroradiometer (MODIS) data have been utilized to retrieve the sea surface temperature (SST) and apparent thermal inertia (ATI). They were used to detect the signature of natural oil seepage in Yingge Sea Basin (YSB) and South Yellow Sea (SYS). In this paper, ATI was used for the first time to detect the signature of natural oil seepage. ATI is an approximation of the real thermal inertia and can be expressed as a function of surface albedo and temperature difference between day and night. Surface albedo can be calculated by weighting spectral reflectivities in visible and near-infrared bands from ASTER data. The spectral reflectivities can be obtained after performing atmospheric correction using the 6S model. An iterative self-consistent split-window algorithm was employed to retrieve the daytime SSTs from ASTER data and nighttime SSTs from MODIS data. Because of the spatial resolution difference between ASTER and MODIS data, the nighttime SST derived from MODIS data was downscaled from 1 km to 90 m using the pixel block intensity modulation (PBIM) method. Two study areas, YSB and SYS, were selected to detect the possible signature of the natural oil seepage. The approximate SST and ATI values in the YSB where natural oil seepage actually developed were derived in advance. A look-up table of albedo, temperature difference and ATI for different sea waters with or without natural oil seepage was constructed. These were then used as prior knowledge to enclose the possible signatures of natural oil seepage in SYS. Our results show that there are some signatures of natural oil seepage in the study area in SYS. Compared with SST, ATI was more sensitive to the signature of natural oil seepage. The reason for this might be that the temperature difference was used in the calculation of the ATI, which decreased the influence of the SST accuracy on ATI values.