Miracle-dz/UniFAR-FTUs huggingface dataset:
Single-Port Insu ation Endoscopic Nipple-Sparing Mastectomy in Early Breast Cancer: A Retrospective Cohort Study

Zi-Han Wang Capital Medical University A liated Beijing Friendship Hospital Wei-Hua Liu Capital Medical University Beijing Obstetrics and Gynecology Hospital Shan-Shan Wu Capital Medical University A liated Beijing Friendship Hospital Yi-Ming Tian Capital Medical University Beijing Obstetrics and Gynecology Hospital Jun Liu Capital Medical University A liated Beijing Friendship Hospital Guo-Xuan Gao Capital Medical University A liated Beijing Friendship Hospital Fang Xie Beijing Hospital of Traditional Chinese Medicine Guo-Qian Ding Capital Medical University A liated Beijing Friendship Hospital Xiang Qu (  cqx3968@ccmu.edu.cn ) Capital Medical University A liated Beijing Friendship Hospital https://orcid.org/0000-0002-79691056
An investigation of influential factors in adopting the cloud computing in Saudi Arabia: an application of technology acceptance model

Cloud computing is an emerging concept in the technological sphere. Its development enables many applications to avail information online and on demand. It is becoming an essential element for businesses due to its ability to diminish the costs of IT infrastructure and is being adopted in Saudi Arabia. However, there exist many factors that affect its adoption. Several researchers in the field have ignored the study of the TAM model for identifying the relevant factors and their impact for adopting of cloud computing
Reliable Communication of Time-and Security-Sensitive Information over a Single Combat Vehicle Network

A common trend, in general as well as in the field of combat vehicles, is the rapidly increasing demand for data network capacity and even more in transferred data. To handle this increased demand, different countries with their armed forces and equipment manufacturers evaluate methods to increase the data transmission capacity in combat vehicles. The different types of transmitted data are of different criticality and have different security demands. An easy solution to this is to have separated networks for each type of traffic, but that is quite expensive and uses a lot of hardware. This thesis focuses on a different solution, with a shared network for all types of data transmissions. This is done by evaluating different types of data networks and add-on protocols and then testing the networks practically with varying transmission rates. In the thesis, all the practical testing is done with data networks according to the Ethernet standard, which is the standard evaluated with a throughput that is high enough for the use case. Ethernet as a standard is not suitable for critical data traffic and therefore add-on protocols for Ethernet to optimize the system for critical data traffic are tested. With these optimizations made, Ethernet can be considered more suitable for critical traffic, but this depends entirely on the system requirements.
A Parametric-Typological Tool: More Diversity for Mass Produced Single Family Homes Through Parametrized Design and Customized Mass Production

We present a research program in which a plug-in tool for the generation of vertically stacked single family homes is developed and implemented in the software Autodesk Revit Architecture. The parametrized typology will provide for more variety, individuality and appropriateness in the homes themselves and also in the urban structures created by them. CAAM methods furthermore drastically reduce the production costs. The research is government-funded and sponsored by the building and software industry with the aim to both extend the functionality of an existing software package and to build a prototype urban development.
Strategic human resource management: assessment and evaluation of human resources as factors to achieving better economic performance

To achieve the economic performance of companies despite the successful selection, the evaluation is important also for the success of the work of managers or managers in various forms of business organizations, especially if it is for profit sector. Therefore it is necessary to conduct research on how successful as organizers and leaders of the working process, both through research their personal characteristics and by assessing their organizational abilities and skills by their colleagues (employees who are hierarchically sort of managers in the organization). Also, for evaluating the performance of human resources in organizations two basic methods are preferred: qualitative and quantitative. The highest quality results are obtained by combining quantitative and qualitative methods. The purpose of this paper is to emphasize the importance of proper assessment of human resource performance, their rewarding, and thus their motivation and effectuation by the application of appropriate standards. Keywords: Evaluation; Selection; Business organizations; Human resources; Economic performance
Customizable, Flexible Pressure, and Temperature Step Sensors with Human Skinlike Color

Durability and multifunctionality are very important factors for human skinlike tactile sensors for measuring physical stimuli if they provide reasonable pressure measurement range and sensitivity. Here, we propose a step tactile sensor with a simple processing unit, showing high repeatability and mechanical stability without drifting caused by thermal and geometrical noise. The proposed sensor, similar to a switch mechanism, detects the applied pressure discretely and has a wide pressure range of 2 kPa to 1.2 MPa according to its geometry. The developed tactile sensor can be designed and fabricated in various morphologies to detect a wide range of tactile stimuli, which help in customizing the sensor as per user demand for practical applications such as a prosthesis arm or hand. It is also easy to extend the sensor size to cover a large area owing to the simple fabrication process by using a 3D printer. Furthermore, with the addition of a flexible exterior layer of leuco dyes and the polydimethylsiloxane mixture, the color of a step tactile sensor not only resembles that of human skin color but also changes its color depending on the temperature changes as human skin does. Thus, the function of a pressure and temperature indicator in a flexible step sensor finds practical applications in various fields, including but not limited to prosthetic applications for the customized and comfortable usage.
Predictors in an infertile population

coefficients were satisfactory. A range of scores was achieved indicating variation in emotional health within the sample. Further refinement of the questionnaire and assessment of its psychometric properties including the assessment of test-retest reliability and construct validity are currently in progress with a second sample of couples undergoing assisted reproduction in Oxford. Conclusions: The EHIQ has been rigorously developed to quantify emotional health in infertility, measuring emotional strain in healthy individuals, rather than psychopathology. It has the potential to be a useful tool in studying issues such as the emotional effects of infertility, the effectiveness of interventions to reduce emotional distress in this population and the influence of emotional health on treatment perseverance and treatment outcome.
CEOR_A_304600 349..358

1Falcon Research Group, North Potomac, MD, USA; 2Manticore Consultancy, Bethesda, MD, USA; 3Mallinckrodt Pharmaceuticals, Hampton, NJ, USA Introduction: Patients with active rheumatoid arthritis (RA) often have inadequately controlled symptoms and are unable to achieve remission or low disease activity despite aggressive treatment. This results in irreversible joint damage, adversely affecting patients’ physical and social functioning. The objective was to estimate the cost-effectiveness of repository corticotropin injection (RCI) versus standard of care (SoC) in patients with active RA from the United States (US) payer and societal perspectives over two to three years. Methods: An individual-level microsimulation was developed to generate individual trajectories for patients with RA, using data from a published Phase 4 trial of RCI. These trajectories report a patient’s disease pathway and associated cost and quality-of-life outcomes. The incremental cost-effectiveness ratio (ICER) of RCI versus SoC was assessed using the literature-derived direct medical and indirect costs, and quality-adjusted life-years (QALY) derived from a Phase 4 trial of RCI. The uncertainty in base case estimates of the parameters was evaluated in the sensitivity analysis. Results: Over two years, RCI has an incremental QALY gain of 1.591 and incremental cost of $183,965 and $117,443 from payer and societal perspective, respectively, resulting in an ICER of $115,629/QALY and $73,817/QALY compared to SoC. Over three years, RCI has an incremental QALY gain of 2.336 and incremental cost of $202,315 and $104,506 from payer and societal perspective, respectively, resulting in an ICER of $86,607/QALY and $44,737/QALY compared to SoC. Results from the probabilistic sensitivity analysis are consistent with those of the base case model. Conclusion: RCI is a cost-effective strategy for patients with persistently active RA who are previously treated with disease-modifying anti-rheumatic drugs and corticosteroids compared to SoC over two to three years from the payer and societal perspectives at a US willingnessto-pay threshold of $150,000/QALY. Further, the economic benefit of RCI is realized with improvement in a patient’s clinical and health outcomes.
Is oxygen therapy bene cial for normoxemic patients with acute heart failure? A propensity score matched study

Yue Yu Changzheng Hospital Ren-qi Yao Chinese PLA General Hospital Yu-feng Zhang Changzheng Hospital Su-yu Wang Changzheng Hospital Wang Xi Changzheng Hospital Jun-nan Wang Changzheng Hospital Xiao-yi Huang Changhai Hospital Yong-ming Yao Chinese PLA General Hospital Zhinong Wang (  wangzn007@smmu.edu.cn ) the Second A liated Hospital of Naval Medical University https://orcid.org/0000-0001-6308-7949
Influence of the Topography in the Calculation of Lightning Induced Voltages on Overhead Lines

HAL is a multi-disciplinary open access archive for the deposit and dissemination of scientific research documents, whether they are published or not. The documents may come from teaching and research institutions in France or abroad, or from public or private research centers. L’archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d’enseignement et de recherche français ou étrangers, des laboratoires publics ou privés. Influence of the Topography in the Calculation of Lightning Induced Voltages on Overhead Lines Edison Soto, Ernesto Pérez
Moderate Alcohol Consumption Reduces Risk of Ischemic Stroke

Background and Purpose—Moderate alcohol consumption is protective against coronary disease, but its relationship to ischemic stroke (IS) is controversial. Methods—Stroke-free participants 40 years of age identified by random-digit dialing were enrolled in a prospective cohort study between 1993 and 2001. Alcohol consumption was assessed through in-person interview and categorized as none in the past year, 1 drink in past month to 2 per day (moderate drinkers), and 2 drinks daily. Lifetime drinking was also assessed. Cox proportional hazard regression modeling was used to assess hazard ratios and their 95% CIs for the association of drinking with risk of stroke and vascular events. Results—Mean age among participants (n 3176) was 69.1 10.3 years; 62.8% were women, 20.8% were non-Hispanic white, 24.5% non-Hispanic black, and 52.4% were Hispanic. No alcohol in the previous year was present in 62.3%, and 32.5% drank moderately. After adjusting for other risk factors compared with those who did not drink in the past year, moderate drinkers had a reduced risk of IS (0.67; 95% CI, 0.46 to 0.99) and IS, myocardial infarction, or vascular death (0.74; 95% CI, 0.59 to 0.94). Results were similar when never-drinkers were used as referent group. Reduction in risk was seen for nonatherosclerotic IS subtypes, and results stratified by age, sex, and race– ethnicity were similar. Conclusion—Moderate alcohol consumption is associated with decreased risk of IS in a multiethnic population. This effect is independent of other risk factors and holds for nonatherosclerotic stroke subtypes. (Stroke. 2006;37:13-19.)
Reply to FOLFIRI plus cetuximab versus FOLFIRI plus bevacizumab as ﬁ rst-line treatment for patients with metastatic colorectal cancer – subgroup analysis of patients with KRAS -mutated tumours in the randomised German AIO

The results of this unplanned retrospective analysis, carried out on 96 KRAS -mutated colorectal cancer patients, did not show any substantial difference in terms of response rate, progression-free and overall survival between anti-epidermal growth factor receptor- and anti-vascular endothelial growth factor-based treatments. These results may be just related to operative bias: for example, the similar response rate observed in the cetuximab and bevacizumab arms is explainable by the lack of independent radiological review and the limitation of standard radiological assessment for anti-angiogenic treatments, which may delay disease progression mainly through disease stabilization: in fact, biological response is often characterized by a reduction of lesions ’ density, without a substantial RECIST response [2].
E MERGENCE OF R AZOR G RASS ON THE B ASIS OF O RIGIN AND IN THE S OIL P

de plântulas obtidas ao longo de 35 dias após a semeadura. As sementes ecótipo Rondonópolis possuem maior as obtidas sementes localizadas superfície ABSTRACT - Razor grass ( Paspalum virgatum L.) is one weed that has gain importance because of its high seed production capability, mainly
Capacity of laying hens in sequential feeding to adjust their feed consumption when offered previously a nutritionally unbalanced diet

HAL is a multi-disciplinary open access archive for the deposit and dissemination of scientific research documents, whether they are published or not. The documents may come from teaching and research institutions in France or abroad, or from public or private research centers. L’archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d’enseignement et de recherche français ou étrangers, des laboratoires publics ou privés. Capacity of laying hens in sequential feeding to adjust their feed consumption when offered previously a nutritionally unbalanced diet Dolores Batonon, Maxime Traineau, Isabelle Bouvarel, L. Roffidal, Philippe Lescoat
the Additive Effects of IL-12 and IL-10 Ligands on Experimental Asthma Depend on Immunomodulatory Effects of Viral TLR

Based on epidemiological data, the hygiene hypothesis associates poor hygienic living conditions during childhood with a lower risk for the development of allergic diseases such as bronchial asthma. The role of viral infections, and especially of viral TLR ligands, within this context remains to be clariﬁed. Viral TLR ligands involve dsRNA and ssRNA which are recognized by TLR-3 or TLR-7, respectively. In this study, we evaluated the impact of TLR-3 or TLR-7 activation on experimental asthma in mice. Systemic application of the synthetic TLR-3 or TLR-7 ligands polycytidylic-polyinosinic acid (p(I:C)) or R-848, respectively, during the sensitization phase prevented the production of OVA-speciﬁc IgE and IgG1 Abs and subsequently abolished all features of experimental asthma including airway hyperresponsiveness and allergic airway inﬂammation. Furthermore, administration of p(I:C) or R-848 to animals with already established primary allergic responses revealed a markedly reduced secondary response following allergen aerosol rechallenges. In contrast to wild-type animals, application of p(I:C) or R-848 to IL-12p35 (cid:1) / (cid:1) mice had no effect on airway inﬂammation, goblet cell hyperplasia, and airway hyperresponsiveness. However, in the absence of IL-12, the numbers of eosinophils and lymphocytes in bronchoalveolar lavage ﬂuids were still signiﬁcantly reduced. These partial effects could also be abolished by neutralizing anti-IL-10 Abs in IL-12p35 (cid:1) / (cid:1) mice. These data indicate that TLR-3 or TLR-7 activation by viral TLR ligands has
Exploring a Semi-Virtual Reality System Impacting Learning Curves of College Students

Virtual reality (VR) is a trending technology used in a broad range of fields including education and has become one of the most promising directions for educators. In this research, the investigation focuses on how the semi-immersive VR application can be used for educational purposes by exploring the VR factors and the interactions between these factors. A theoretical learning framework is also proposed to offer an explanation for the beneficial effects of education brought by VR at a high level. This research consists of three parts. First, this research will introduce the development of Walk-in-Place Learning System (WIPLS), a semi-immersive VR system that is highly customizable and can be modified into different sub-VR systems that enable the tuning of various VR factors. Second, it will present the survey instrument obtained from previous literature related to educational VR systems. Two individual pilot studies will be conducted: 1) to verify the performance of the WIPLS, and 2) to validate the internal consistency of the survey instrument. Third, an empirical study will be conducted on a sample population to answer the research question, and to analyze the statistical results to validate the research model. Based on these statistical results, this research will propose conclusions and insights in how VR factors, as well as interactions, are affecting the learning outcome in an educational VR system, and provide guidance and suggestions for VR practitioners to design the development of VR systems.
STUDI PERBANDINGAN KONFIGURASI KOIL METODA EDDY CURRENT TESTING (ECT) PADA BAHAN FERROMAGNETIK DAN NON-FERROMAGNETIK

Rapidly evolving technology is currently the effect of increasing human needs, one of which the inspection technology. Inspection technology is a systematic and independent process for obtaining evidence and evaluating it objectively inspection to determine the extent to which inspection criteria are met. Various stages of inspection have been developed at this time ranging from Destructive Testing and Non-Destructive Testing. As of the development of technology, Non-Destructive Testing methods are often used to do the testing, because the method of Non-Destructive Testing is testing without damaging the object direct contact. Non-Destructive Testing has several methods, one of which Eddy Current Testing methods used in the research topic of this thesis. In this research, the test object to be used in the form of a ferromagnetic material and non-ferromagnetic. It is known that the non-ferromagnetic material is a material that has a very low magnetic properties. Therefore, this research will compare the test object is ferromagnetic and non-ferromagnetic. Testing each using a different coil configurations to get the right coil configuration to produce potential data on the object.
he hidden secrets of the hibernator ’ s heart may protect gainst arrhythmias

p n o b t r 1 r o s p d p b a t t d s 9 s c d r f h i s a h t b t t u H j l a C v i In this issue of Heart Rhythm, Fedorov et al describe the ctivation pattern and other electrophysiologic features of he heart of Citellus undulatus (also known as Spermophilus ndulatus), the Siberian ground squirrel, both in summer ctive and in winter hibernating animals at temperatures arying from 3°C to 37°C and compared those with data in he rabbit heart as a nonhibernating species. The summary f the data can be simple. There is a substantial decrease in onduction velocity from 70–80 cm/s in the Siberian round squirrel at 37°C to 5–10 cm/s at 3°C. However, the onduction patterns remain normal and do not show areas of ubstantial conduction block, which might herald arrhythias. Interestingly, conduction velocity was significantly igher in hearts obtained from winter hibernating animals han from summer active animals at both 37°C and 3°C. ata at such low temperatures cannot be obtained from the earts in nonhibernating species such as the rabbit in the resent study, but also not in man, because their hearts ecome quiescent or develop ventricular fibrillation at temeratures below 20°C. Moreover, the authors show that here is an up-regulation of connexin43 (Cx43) in working entricular myocardium of hibernating animals, in line with revious research, and an appearance of connexin45 Cx45) in working ventricular myocardium, although the xpression of the latter normally is restricted to the conducion system. This study underscores the presence of differences not nly between hibernating and nonhibernating species but lso between hibernating and nonhibernating individuals of he same species, with all the interesting implications for egulatory mechanisms.
CITRUS LIMON DISEASES – A REVIEW

Citrus is considered as one of the most important tropical fruit crop in India. It plays a vital role in the fruit economy of the country next to mango. Citrus cultivation in India is facing plethora of production constraints viz., non availability of disease free planting material, bud wood transmissible diseases, general neglect, scarcity of water and poor management practices, cultivation in unsuitable soils. Beside this, Citrus spp. are prone to attack by more than 150 diseases and disorders caused by fungal, viral and few bacterial pathogens right from nursery level to bearing stage resulting in considerable yield losses. Citrus canker is a serious bacterial disease of commercial varieties of citrus, and relatives, caused by the bacterium Xanthomonas citri subsp. citri. It is a serious menace to our most valued citrus orchards causing objectionable blemishes on the fruit. The disease causes serious damage in India, China, Japan and Java. At least 3 distinct forms or types of citrus canker are recognized. Among these, Asiatic form (Canker A) is the most destructive and affects most of the major citrus cultivars. Severe infection of the disease produces a variety of effects including defoliation, dieback, severely blemished fruit, reduced fruit quality and premature fruit drop. Warm, humid, cloudy climate, along with heavy rainfall and strong wind promotes the disease. Citrus canker has resulted in heavy economic losses to citrus industries across the globe, due to damage to trees, reduced fruit production and access to export markets and increased cost of management.
A New Transform-Domain Regularized Recursive Least M-Estimate Algorithm for a Robust Linear Estimation

This brief proposes a new transform-domain (TD) regularized M-estimation (TD-R-ME) algorithm for a robust linear estimation in an impulsive noise environment and develops an efficient QR-decomposition-based algorithm for recursive implementation. By formulating the robust regularized linear estimation in transformed regression coefficients, the proposed TD-R-ME algorithm was found to offer better estimation accuracy than direct application of regularization techniques to estimate system coefficients when they are correlated. Furthermore, a QR-based algorithm and an effective adaptive method for selecting regularization parameters are developed for recursive implementation of the TD-R-ME algorithm. Simulation results show that the proposed TD regularized QR recursive least M-estimate (TD-R-QRRLM) algorithm offers improved performance over its least squares counterpart in an impulsive noise environment. Moreover, a TD smoothly clipped absolute deviation R-QRRLM was found to give a better steady-state excess mean square error than other QRRLM-related methods when regression coefficients are correlated.