Miracle-dz/UniFAR-FTUs huggingface dataset:
Exploring Barriers to Implementing Telerehabilitation from experiences of managers, policymakers, and providers of rehabilitation services in Iran: A Qualitative Study

Background:Telerehabilitation is an emerging technology that uses digital technologies to perform evaluation, counseling, treatment, and telemonitoring to provide rehabilitative care to patients in various locations such as homes, communities, health centers, and workplaces. This approach has advantages such as reducing costs and overcoming barriers of distance and time. Reducing patient-rehabilitator interaction, and being hard to teamwork and express thoughts and feelings are some disadvantages of this approach. TR services are provided by a variety of rehabilitation specialists. The aim of the study was to identify barriers in the way of implementing TR in Iran Methods:This study was conducted using a conventional content analysis method based on a qualitative approach. 26 people were selected as participants based on purposive sampling with maximum diversity. Data were collected through semi-structured interviews and managed using MAXQDA 10 software. Results:765 codes were extracted by conducting interviews and coding. The findings of this study are classified into seven main categories and 32 sub-categories. The main categories are insufficient infrastructure, legal, physical, and moral hazards, lack of priority and insufficient determination, insufficient support of the public and non-governmental organizations, poor knowledge in using equipment, Lack of knowledge and negative attitude, and low capacity in comparison with face-to-face rehabilitation. Conclusion:This study shows that based on the insights from the experiences of participants, inadequate infrastructure and poor knowledge of the use of equipment are the most important obstacles in the way of TR. This study reveals that the implementation of TR in Iran encounters several obstacles and eliminating them requires serious effort.
Remote Filter Design for Discrete Singular Systems

In this paper, a remote filter design problem for a discrete-time singular plant under a networked control system is investigated. For a remote system, it is natural that transmitted signals have some delayed phenomenon and some data losing due to heavy loaded networks or under unreliable communication envelopment. In this case, a Bernoulli random distributed sequence is introduced to model the possible data losing, as well as the working but delayed transmitted signals are limited in some time interval. Applying a finite sum inequality approach, a set of delay dependent sufficient conditions for the admissibility analysis and the filter design problems are derived under an LMI framework. In order to verify and show the efficiency of the proposed method for such problem formulation, a numerical example is presented at the end of this paper.
Bonding of silicon wafers for silicon‐on‐insulator

Several aspects of a new silicon‐on‐insulator technique utilizing bonding of oxidized silicon wafers were investigated. The bonding was achieved by heating in an inert atmosphere a pair of wafers with hydrophilic surfaces contacted face‐to‐face. A quantitative method for the evaluation of the surface energy of the bond based on crack propagation theory was developed. The bond strength was found to increase with the bonding temperature from about 60–85 erg/cm2 at room temperature to ≂2200 erg/cm2 at 1400 °C. The strength was essentially independent of the bond time. Bonds created during 10‐s annealing at 800 °C were mechanically strong enough to withstand the mechanical and/or chemical thinning of the top wafer to the desired thickness and subsequent device processing. A model was proposed to explain three distinct phases of bonding in the temperature domain. Electrical properties of the bond were tested using metal‐oxide‐semiconductor (MOS) capacitors. The results were consistent with a negative charge de.
Linewidth narrowing in Brillouin lasers: Theoretical analysis

The linewidth narrowing observed in Brillouin fiber ring lasers is studied within the framework of the usual three-wave model of stimulated Brillouin scattering. We show that the phase noise of the pump laser is transferred to the emitted Stokes wave after being strongly reduced and smoothed under the combined influence of the acoustic damping and the cavity feedback. We then derive a simple analytical relation connecting the full width at half maximum of the Stokes linewidth to that of the pump laser.
c‐axis inclined ZnO piezoelectric shear wave films

This letter reports on the growth and characterization of ZnO films having c axis oriented 40° to the substrate normal. These films are of significant interest for shear wave generation for bulk wave delay lines and resonators. The films were grown on Si wafers or membranes under low pressure and high growth rate conditions in a reactive dc planar magnetron sputtering system having an auxiliary anode structure. Shear wave resonators were fabricated and used for film evaluation. A ZnO/Si composite resonator exhibited a Q of approximately 4600 at 293‐MHz fundamental resonance. The effective coupling coefficient of the film alone was found to be 17% (k2=0.029) using an edge‐only supported ZnO plate resonator. The temperature coefficient of the ZnO resonator was found to be −36 ppm/°C and −20.5 ppm/°C for the composite structure.
A 16 Epithelia-Mesenchymal Transition Associated LncRNAs Signature to Optimize Prognosis Predication of Stomach Adenocarcinoma

The study aimed to identifying critical long non-coding RNAs (lncRNAs) and constructed a prognostic signature to optimize prognosis predication of patients with Stomach Adenocarcinoma (STAD). STAD is a common malignant tumor with high metastasis rate and low survival rate. LncRNAs participate in the regulation process of epithelial-mesenchymal transition (EMT) and development of STAD. RNAseq data was obtained from TCGA-STAD, while 200 EMT-associated genes (EAGs) from ‘HALLMARK_EPITHELIAL_MESENCHYMA-L _TRANSITION’ gene set. Differentially expressed EAGs and EMT-associated lncRNAs (EALs) were identified. Moreover, Lasso Cox regression analysis was used to construct a signature of differentially expressed EALs, and univariate and multivariate analyses, Kaplan-Meier analysis, receiver operating characteristic curve (ROC) analysis and nomogram were conducted to predict its prognostic value. Enrichment functional analysis was performed. Quantitative Real-Time PCR (qRT-PCR) was used to determine lncRNAs expressions in cell lines. A total of 52 differentially expressed EAGs and 320 EALs were identified in this study. Meanwhile, 16 EALs was used to construct the signature, and further analysis indicated that it had high prognostic value for STAD patients. Enrichment functional analysis revealed the signature was correlated to tumor immunity in STAD. Moreover, three novel EALs expressions were confirmed in cell lines. A novel survival signature was established to predict and evaluate prognosis of STAD patients.
Melanism in the grass snake Natrix natrix (Linnaeus, 1758) from the Danube Delta Biosphere Reserve, Romania

Animal colouration has a significant ecological role in defence, reproduction, and thermoregulation. In the case of melanism, it is a complex topic. Besides potential disadvantages such as higher risk of predation, melanistic ectotherms may have certain physiologi - cal advantages such as more efficient thermoregulation in colder climates and thus, reduced basking time. The common grass snake ( Natrix natrix ) is a widespread species throughout Europe and Asia. It exhibits a wide range of colour polymorphisms, from olive to dark grey, even albinistic and melanistic. Between 2016 and 2021, we conducted fieldwork in the Danube Delta Biosphere Reserve (DDBR) with the aim to document the geographic range of melanistic grass snakes. We categorised the melanistic expressions of N. natrix individuals as melanotic, completely melanistic, and partially melanistic. Melanistic snakes were encountered in all six localities visited, suggesting that the occurrence of melanistic grass snakes in the DDBR is geographically widespread. We observed both juveniles (n=2) and adults (n=11) with melanism, suggesting that individuals are born melanistic. However, the proportion of melanistic individuals in the general population of N. natrix from the DDBR is unknown. Only at Histria locality we studied the proportion of melanism in the grass snake population and 6.3% of the snakes caught were melanistic. Body size comparisons are not statistically significant because of the low sample size. The N. natrix melanistic morph’s geographical distribution in the DDBR is most likely due to an interaction of climate and habitats, which offer a thermal advantage in the face of predation pressure.
Optimality of the greedy algorithm for some function classes

The convergence rate of the pure greedy algorithm (PGA) is considered. Upper bounds for the convergence rate of the PGA are obtained in the case of the target function in the classes , , which are extensions of the class . This bound is shown to be sharp in order for . Bibliography: 14 titles.
Hyaluronic Acid as a Modern Approach in Anticancer Therapy-Review

Hyaluronic acid (HA) is a linear polysaccharide and crucial component of the extracellular matrix (ECM), maintaining tissue hydration and tension. Moreover, HA contributes to embryonic development, healing, inflammation, and cancerogenesis. This review summarizes new research on the metabolism and interactions of HA with its binding proteins, known as hyaladherins (CD44, RHAMM), revealing the molecular basis for its distinct biological function in the development of cancer. The presence of HA on the surface of tumor cells is a sign of an adverse prognosis. The involvement of HA in malignancy has been extensively investigated using cancer-free naked mole rats as a model. The HA metabolic components are examined for their potential impact on promoting or inhibiting tumor formation, proliferation, invasion, and metastatic spread. High molecular weight HA is associated with homeostasis and protective action due to its ability to preserve tissue integrity. In contrast, low molecular weight HA indicates a pathological condition in the tissue and plays a role in pro-oncogenic activity. A systematic approach might uncover processes related to cancer growth, establish novel prognostic indicators, and identify potential targets for treatment action.
Dispersed T Tauri stars and galactic star formation

The spatial distribution, age distribution and kinematics of T Tauri stars, both close to and widely distributed around active clouds, are considered using simple models of T Tauri dispersal. Models are compared to observations in and around the nearby cloud complexes, in particular the recent discovery of widely scattered young stars from the ROSAT All-Sky Survey. We suggest the dispersal of T Tauri stars has two major causes: slow isotropic drifting of stars away from long-lived star forming clouds, and star formation in short-lived rapidly moving cloudlets associated with large-scale turbulent motions of molecular cloud complexes. A third mechanism for dispersal, dynamical ejection of high velocity T Tauri stars, appears to be less important. Other implications include: star formation in at least one cloud (Chamaeleon I) has been continuous for ≃20 Myr; star formation efficiencies of clouds may often be 20% or higher; a large fraction of low-mass stars may form in small shoft-lived cloudlets each produ.
Automated Image Analysis Reveals Different Localization of Synaptic Gephyrin C4 Splice Variants

Abstract Postsynaptic scaffolding proteins function as central organization hubs, ensuring the synaptic localization of neurotransmitter receptors, trans-synaptic adhesion proteins, and signaling molecules. Gephyrin is the major postsynaptic scaffolding protein at glycinergic and a subset of GABAergic inhibitory synapses. In contrast to cells outside the CNS, where one gephyrin isoform is predominantly expressed, neurons express different splice variants. In this study, we characterized the expression and scaffolding of neuronal gephyrin isoforms differing in the inclusion of the C4 cassettes located in the central C-domain. In hippocampal and cortical neuronal populations, gephyrin P1, lacking additional cassettes, is the most abundantly expressed isoform. In addition, alternative splicing generated isoforms carrying predominantly C4a, and minor amounts of C4c or C4d cassettes. We detected no striking difference in C4 isoform expression between different neuron types and a single neuron can likely express all C4 isoforms. To avoid the cytosolic aggregates that are commonly observed upon exogenous gephyrin expression, we used adeno-associated virus (AAV)-mediated expression to analyze the scaffolding behavior of individual C4 isoforms in murine dissociated hippocampal glutamatergic neurons. While all isoforms showed similar clustering at GABAergic synapses, a thorough quantitative analysis revealed localization differences for the C4c isoform (also known as P2). Specifically, synaptic C4c isoform clusters showed a more distal dendritic localization and reduced occurrence at P1-predominating synapses. Additionally, inhibitory currents displayed faster decay kinetics in the presence of gephyrin C4c compared with P1. Therefore, inhibitory synapse heterogeneity may be influenced, at least in part, by mechanisms relating to C4 cassette splicing.
Percutaneous Transluminal Renal Angioplasty for Fibromuscular Dysplasia and Prognostic Risk Factors: A Retrospective Chinese Cohort Study

Fibromuscular dysplasia (FMD) is a non-atherosclerotic, non-inflammatory vascular disease involving small-to-medium-sized arteries. The characteristics of Chinese patients with FMD remain unclear. We retrospectively analyzed the data of patients with renal FMD who underwent percutaneous transluminal renal angioplasty (PTRA) for the first time at Fuwai Hospital between 2010 and 2021. The variables were selected through least absolute shrinkage and selection operator regression (LASSO), and logistic regression models were constructed to identify independent risk factors. A total of 116 patients (52 males, median age at diagnosis, 25.0 years) were enrolled. Elevated blood pressure was the leading complaint. After a median follow-up period of 18.0 months (interquartile range: 6.0–48.0 months), hypertension recurred in 34 patients and restenosis in nine patients, among whom four patients underwent secondary intervention and one patient underwent surgical revascularization. Bilateral renal artery involvement (odds ratio [OR]: 2.61, 95% confidence interval [CI]: 1.11–6.15; p = 0.028) and age at hypertension onset (OR: 0.93, 95% CI: 0.88–0.99; p = 0.018) were independent prognostic factors for adverse outcomes. The results indicate that patients with bilateral renal artery involvement and younger age at hypertension onset are more likely to have poorer clinical outcomes after PTRA, and should be more closely monitored.
Further Evidence of the Mesoscale and Turbulent Structure of Upper Level Jet Stream–Frontal Zone Systems

Abstract Recent aircraft observations of the mesoscale and turbulent structure of upper level frontal zone-jet stream systems provide further evidence of stratosperic mesoscale cyclonic wind shear and associated anomalously high values of potential vorticity in the layer of maximum wind. Measurements of turbulent heat flux in regions of clear air turbulence above and below the layer of maximum wind (LMW) document the first-order importance of turbulent-scale processes in the generation and dissipation of potential vorticity. Ozone concentration measurements illustrate the intrusion of stratospheric air into the troposphere and give evidence of the effect of turbulent mixing processes in the LMW. It is proposed that the nonconservative property o@ potential vorticity permits air parcels to enter the stratosphere by direct transport across the potential vorticity discontinuity in the LMW, in agreement with earlier isentropic trajectory calculations.
A Review of Social Media Efficiency Over a 3-Year Period to Promote a Hospitality Management Program at a Southwestern University

Social media is utilized in marketing to maximize outreach, and within higher education, its use has been growing to engage a variety of stakeholders and recruit students. This paper compared the efficiency of three marketing campaigns using Facebook and Google Search Engine Management (SEM) over three years in support of promoting a new hospitality management program at a southwestern university. The findings may provide insights into a better understanding of the attitudes and consumption behaviors of students and parents, and the efficiency of utilizing social media through the lens of a comparative 3-year timeline in the period before and during the Covid-19 pandemic.
Modeling the Dynamics of Malaria Transmission with Bed Net Protection Perspective

We propose and analyze an epidemiological model to evaluate the effectiveness of bed nets as a prophylactic measure in malaria-endemic areas. The main purpose in this work is the modeling of the aggressiveness of anopheles mosquitoes relative to the way humans use to protect themselves against bites of mosquitoes. This model is a system of several differential equations: the number of equations depends on the particular assumptions of the model. We compute the basic reproduction number, and show that if, the disease free equilibrium (DFE) is globally asymptotically stable on the non-negative orthant. If, the system admits a unique endemic equilibrium (EE) that is globally and asymptotically stable. Numerical simulations are presented corresponding to scenarios typical of malaria-endemic areas, based on data collected in the literature. Finally, we discuss the relative effectiveness of different kinds of bed nets.
Consumer Ethnocentrism on the Market for Local Products: Determinants of Consumer Behaviors

Abstract The aim of the study was to determine the attitudes and ethnocentric behaviors of consumers on the local food market. The survey also included consumers’ purchasing channels, which helped determine the specifics of local product distribution. The criterion for classifying the respondent into the research sample was to indicate the economic motives of consumer ethnocentrism as a factor in the purchase decision. 1,009 correctly completed questionnaires were accepted for analysis. Descriptive statistics and the U Mann–Whitney test were used in the analyses. The results made it possible to determine the products appreciated by respondents, such as eggs, dairy products, and groats. Local alcoholic beverages in the categories “local wines” and “craft beers” were appreciated more by men. The respondents had the lowest interest in oils produced locally. Among the features with which consumers associate local food are producer identification, freshness, good taste, and affordability. Consumers take advantage of short supply chains such as direct sales by the producer or take the opportunity to buy products at local events or thematic trips such as the culinary trail. Consumers are able to accept a price increase of 10–15%, with larger increases they start looking for cheaper substitutes. In conclusion it was stated that the market for local products is a source of support for the local economy, therefore the authorities should create conditions for its development through undertaking appropriate measures promoting local products.
Toxicity of Toddalia asiatica is associated with microcephaly and hypochondroplasia in mice

In Kenya various plant extracts are widely used as folklore remedies for various ailments including malaria etc. However, use of these traditional remedies poses a risk to the users due to the scarcity of data on their safety including their teratogenic potential. Hence this study evaluated the teratogenic and sub-acute toxic effects of methanol: dichloromethane extract of Toddalia asiatica in animal mice. In the study, young female mice aged between 6-7weeks were mated with mature males and conception confirmed using vaginal plug, maternal weight and breast enlargement. Administration of the dosed of the plant extract and controls was done from day 6 through 15 of gestation. The mice were euthanized on the 19th day of gestation. The weight of the gravid uterus, pups, number of pups and gross examination to identify any physical abnormalities was done. In the toxicity study male mice aged between 6-7 weeks received oral administration of high doses of plant extract and the control daily for 28days. On the 29th day animals were sacrificed, cardiac puncture conducted and collected blood for hematology and biochemistry analysis. The data obtained was analyzed using one way ANOVA followed by Tukey as the post hoc test. Statistical significance was set p < 0.05. The extracts caused significant reduction (p<0.001) in head size, birth weights and length of the limbs but no effects on hematology parameters. Hence the plant extract exhibited teratogenic effects and thus should be used with care during pregnancy.
Performance of Pathognomonic Magnetic Resonance Imaging Findings for Diagnosis of Triple Negative Breast Cancers

Background: Triple Negative Breast Cancer (TNBC) has the worst prognosis of any subtype of the disease because of tumor heterogeneity and a chronic lack of other effective treatment lines. To improve the low survival rate, early identification is the key. Objective: Our study aimed to determine the accuracy of Dynamic Contrast-Enhanced Magnetic Resonance Imaging (DCE-MRI) in differentiating TNBC from other Non-Triple Negative Breast Cancer (NTNBC) subtypes using pathological examination as the gold standard. Subjects and procedures Retrospective study was conducted at the Radio-diagnosis, Oncology, and Surgery departments of Meet Ghamr Oncology center, enrolling 68 female patients with pathologically proven 83 malignant breast lesions of different immunochemistry subtypes, consisting of TNBC (22 patients/29 lesions) and NTNBC (46 patients /54 lesions). Every patient received both conventional and (DCE) MRI scans, which are compared to histopathological and immune-chemistry analyses. Results: TNBC and NTNBC subtypes groups differed significantly (p<0.05) in terms of the tumor's size, shape, Apparent Diffusion Coefficient (ADC) value, enhancement shape and distribution, and specific criteria like central necrosis and peritumoral high T2 Weighted Image (T2WI) signal. There was a highly significant difference (p<0.001) between the two groups in terms of (Patient age, histologic grade, tumor margin, lesion-high T2W signal, and enhancement pattern). Validity values for differentiating between TNBC and NTNBC using combined DCE-MRI and MRI-Specific criteria were (100%, 91.49%, 87.1%, and 100%) as opposed to (88.89%, 97.87%, 96%, and 93.9%) Conclusions: The results of our study demonstrated the possibility of MRI-based imaging criteria for more accurate prediction and differentiation of TNBC from other subtypes.
Structural and cathodoluminescence properties of ZnO nanorods after Ga-implantation and annealing

Single-crystalline ZnO nanorods were implanted with 30 keV Ga+ ions and fluences between 5×1012 and 1.5×1016 cm−2. Annealing treatments at temperatures up to 700 °C for 1 h were carried out to reduce implantation-induced structural defects. The structural and optical properties of the nanorods were studied by transmission electron microscopy (TEM) and cathodoluminescence (CL) spectroscopy. TEM shows that extended implantation defects vanish completely in nanorods implanted with doses up to 5×1013 cm−2 after annealing at 700 °C. Dislocation loops remain after implantation with higher fluences. The CL intensity of as-grown nanorods and implanted ZnO nanorods is low. Annealing at 700 °C leads to a significant increase in the CL intensity for as-grown nanorods and implanted with a dose of up to 5×1013 cm−2. The strong CL intensity in implanted and annealed nanorods correlates with the complete disappearance of extended structural defects.