Miracle-dz/UniFAR-FTUs huggingface dataset:
Playing the computer game Tetris prior to viewing traumatic ﬁ lm material and subsequent intrusive memories: Examining proactive interference Experimental Psychiatry

Background and objectives: Visuospatial working memory (WM) tasks performed concurrently or after an experimental trauma (traumatic ﬁ lm viewing) have been shown to reduce subsequent intrusive memories (concurrent or retroactive interference, respectively). This effect is thought to arise because, during the time window of memory consolidation, the ﬁ lm memory is labile and vulnerable to interference by the WM task. However, it is not known whether tasks before an experimental trauma (i.e. proactive interference) would also be effective. Therefore, we tested if a visuospatial WM task given before a traumatic ﬁ lm reduced intrusions. Findings are relevant to the development of preventative strategies to reduce intrusive memories of trauma for groups who are routinely exposed to trauma (e.g. emergency services personnel) and for whom tasks prior to trauma exposure might be bene ﬁ cial. Methods: Participants were randomly assigned to 1 of 2 conditions. In the Tetris condition (n ¼ 28), participants engaged in the computer game for 11 min immediately before viewing a 12-min traumatic ﬁ lm, whereas those in the Control condition (n ¼ 28) had no task during this period. Intrusive memory frequency was assessed using an intrusion diary over 1-week and an Intrusion Provocation Task at 1- week follow-up. Recognition memory for the ﬁ lm was also assessed at 1-week. Results: Compared to the Control condition, participants in the Tetris condition did not report statistically signi ﬁ cant difference in intrusive memories of the trauma ﬁ lm on either measure. There was also no statistically signi ﬁ cant difference in recognition memory scores between conditions. Limitations: The study used an experimental trauma paradigm and ﬁ ndings may not be generalizable to a clinical population. Conclusions: Compared to control, playing Tetris before viewing a trauma ﬁ lm did not lead to a statistically signi ﬁ cant reduction in the frequency of later intrusive memories of the ﬁ lm. It is unlikely that proactive interference, at least with this task, effectively in ﬂ uences intrusive memory development. WM tasks administered during or after trauma stimuli, rather than proactively, may be a better focus for intrusive memory amelioration.
THE EFFECT OF FOLIAR SPRAYING ROYAL JELLY ON GROWTH AND FRUITING OF ZEBDA MANGO TREES GROWN UNDER ASWAN REGION CONDITIONS

During 2015 and 2016 seasons, Zebda mango trees treated once (at the beginning of growth), twice (at growth the beginning and again just after fruit setting), or thrice (at growth start, just after fruit setting and at one month later) with Royal Jelly at 0.0125 up to 0.05 %. The effects of Royal jelly treatments on growth and fruiting of the trees were investigated. Treating the trees once, twice, or thrice with Royal Jelly at 0.0125 up to 0.05% caused a remarkable promotion on all growth characteristics, leaf pigments and various nutrients, yield as well as both physical and chemical characteristics of the fruits compared with the control treatment. There was a gradual promotion on growth traits, nutrients, yield and fruit quality with increasing concentrations and frequencies of application of Royal Jelly.The differences between the two higher concentrations (0.025 & 0.05%) and frequencies (twice & thrice) as promotion on these parameters were insignificantly effected in both seasons. Conclusively, the best results with regard to yield and fruit quality of Zebda mango trees grown under Aswan region conditions were obtained when the trees sprayed twice at growth start and again just after fruit setting with Royal Jelly at 0.025%.
Comprehensive evaluation of Hybrid RNN Model embedded with LSTM and GRU Layers for Text Classification

— Though text classification has gained great importance over a decade, there are umpteen number of methods developed to address the challenges pertaining to text classification. Text classification has moved towards neural networks from the conventional machine learning algorithms to address the intricacies embedded in the process of classification. The present work aims at exploring two such neural networks viz. Region Based Convolutional Neural Network (RCNN) and hybrid Recurrent Neural Network (RNN) embedded with 3 layers of LSTM and 2 layers of GRU. GloVE dataset is used to train the models and the precision and recall of the models are evaluated. The performances of both the models are compared based on the F1 score. RCNN model is embedded with four convolution layers and four LSTM layers, while RNN model is provided with four GRU layers. The weighted average for RCNN is found to be 0.69 whereas RNN weighted average is 0.77. RNN outperformed RCNN for lesser number of epochs, which is indicative that RNN can be much easily trained when, compared RCNN without compromising the prediction accuracy.
Bayes Classification for the Fingerprint Retrieval

: The Fingerprint is the most commonly used biometric property in security, commerce, industrial, civilian and forensic applications. The goal is to raise the recognition rate in the fingerprint retrieval system. In this work, the Bayes classifier is adopted assuming Gaussian statistics. The set of training samples are expanded by spatial modeling technique and implement a variant of the Fisher’s Linear Discriminant Analysis (FLDA) for dimension reduction and Quadratic Discriminant Analysis (QDA) for lowering estimation errors. Finally calculating the probabilistic features for Gabor and Minutiae which helps to reduce the error rate about 75% which outperforms the K-NN classifier where the error rate was about 30-60%. The accuracy and Speed are evaluated using FVC2004 database and satisfactory retrieval performance is achieved. Thus the objective of the Fingerprint Retrieval system that is efficient and accurate is build.
APLICAÇÃO DO KANBAN ELETRÔNICO EM UM PROCESSO DE FABRICAÇÃO: UM ESTUDO DE CASO

O KANBAN é um subsistema do Sistema Toyota de Produção (TPS), que foi criado para controlar o nível de inventário, a produção e o fornecimento de componentes, e, em alguns casos, matéria-prima. Existe um conside¬rável número de possibilidades no uso deste sistema, que são oriundas da dificuldade de se utilizar o sistema KANBAN na forma como foi concebido originalmente em situações adversas às quais as empresas têm sido submetidas ultimamente. A aplicação na prática de adaptações somente desenvolvidas de forma teórica e a validação prática de vantagens e desvantagens destes sistemas são temas ainda com muita oportunidade de exploração. Neste sentido, os sistemas desenvolvidos utilizando o conceito de transferência eletrônica de informações ganham destaque. Com o intuito de contribuir com as pesquisas neste campo, o objetivo deste trabalho é analisar uma aplicação prática do sistema KANBAN com utilização de transferência eletrônica de informações e comparar com o sistema KANBAN tradicional, por meio de um estudo de caso em uma empresa multinacional do segmento de automação industrial. Como resultados, o estudo identifica as principais diferenças entre o sistema eletrônico e o convencional, os benefícios, desvantagens e as dificuldades para a implementação deste tipo de sistema. O trabalho também remete a temas de possíveis pesquisas futuras relacionadas ao assunto e implicações gerenciais.
Curcumin Inhibited Endothelin-1 mRNA Expression Induced by TGF- β in Bovine Aortic Endothelial Cell

Objectives: Curcumin is a plant polyphenol compound used as a traditional supplement in many countries. The potential therapeutic or preventive eﬀects of curcumin may be related to its antioxidant and anti-inﬂammatory properties. The current in vitro studyaimedtoinvestigatetheeﬀectof curcuminontheexpressionof endothelin-1(ET-1)stimulatedbytransforminggrowthfactor-beta (TGF- β ) in bovine aortic endothelial cells (BAECs). Methods: Bovine aortic endothelial cells derived from bovine aorta were maintained in low glucose DMEM (Dulbecco’s modiﬁed Eagle’s medium). The time-course and diﬀerent concentrations of TGF- β (2 ng/mL and 10 ng/mL) were used to evaluate ET-1 mRNA expression. Also,theBAECsweretreatedwith10 µ Mof SB431542(chemicalinhibitorof TGF- β receptor)aspositivecontrolanddiﬀer-ent doses of curcumin (5 µ M, 10 µ M, and 15 µ M). The expression of ET-1 mRNA was quantiﬁed by quantitative real-time polymerase chain reaction (qPCR). Statistical analysis was performed by one-way ANOVA with SPSS software. Results: ET-1 mRNA expression signiﬁcantly increased in six hours in the TGF- β -treated group (2.79 ± 0.9). SB431542, as well as curcumin10 µ Mand15 µ Msigniﬁcantlydecreasedtheexpressionof ET-1mRNAby2.3 ± 0.15,1.5 ± 0.16,and1.02 ± 0.01,respectively. Conclusions: Curcumin downregulated ET-1 mRNA; this result suggested a possible underlying molecular mechanism mediated through ET-1 to exert its anti-inﬂammatory and antioxidant properties.
Air-Sea CO 2 Exchange in the Ross Sea, Antarctica

Although the Ross Sea is one of the most productive regions in Antarctica, it is not clear to what extent this region is an atmospheric CO 2 sink. We calculate instantaneous CO 2 ﬂux rates with in situ p CO 2 and wind speed data from 20 cruises in the Ross Sea. In addition, we estimate annual CO 2 ﬂuxes into the Ross Sea with nutrient budgets from a late summer cruise. We ﬁnd that the Ross Sea is a lesser atmospheric CO 2 sink (–7.5 6 0.5 Tg C yr 2 1 , 2 1.3 6 0.1 mol C m 2 2 yr 2 1 ) than previously reported (–13 Tg C yr 2 1 , 2 1.7 to 2 4.2 mol C m 2 2 yr 2 1 ). One exception is Terra Nova Bay (TNB) in the western Ross Sea, with CO 2 ﬂux rates (–4.8 6 0.3 mol C m 2 2 , January–March) that are 3–4 times greater than the Ross Sea mean. The majority of the CO 2 ﬂux into TNB occurs during the late summer with instantaneous CO 2 ﬂux rates up to 2 246 mmol C m 2 2 d 2 1 . These extraordinary CO 2 ﬂux rates are caused by the unique coupling of strong katabatic winds and low surface p CO 2 values. Although strong katabatic winds deepen the mixed layer and entrain CO 2 -rich water from below, late season net community productivity maintains low surface water p CO 2 levels. While TNB only covers (cid:2) 1% (3,600 km 2 ) of the Ross Sea continental shelf, extraordinary air-to-sea CO 2 ﬂuxes during the late summer may be regular features in many of the major sea ice production polynyas (148,000 km 2 combined), including Antarctic Bottom Water formation regions.
Molecular BioSystems

The extant layout of the s 54 promoter Pu , harboured by the catabolic TOL plasmid, pWW0, of Pseudomonas putida is one of the most complex instances of endogenous and exogenous signal integration known in the prokaryotic domain. In this regulatory system, all signal inputs are eventually translated into occupation of the promoter sequence by either of two necessary components: the m -xylene responsive transcriptional factor XylR and the s 54 containing form of RNA polymerase. Modelling of these components indicated that the Pu promoter could be upgraded to respond with much greater capacity to aromatic inducers by artificially increasing the endogenous levels of both XylR and the s 54 sigma factor, either separately or together. To explore these scenarios, expression of rpoN , the gene encoding s 54 , was placed under the control of an orthogonal regulatory system that was inducible by salicylic acid. We generated a knock-in P. putida strain containing this construct alongside the xylR / Pu regulatory module in its native configuration, and furthermore, a second strain where xylR expression was under the control of an engineered positive-feedback loop. These interventions allowed us to dramatically increase the transcriptional capacity ( i.e. absolute promoter output) of Pu far beyond its natural scope. In addition, they resulted in a new regulatory device displaying more sensitive and ultra-fast responses to m -xylene. To our knowledge, this is the first time that the working regime of a promoter has been rationally modified by releasing the constraints imposed by its innate constituents.
DENSITY AND DEMOGRAPHICS IN LOS ANGELES TRANSIT ORIENTED DEVELOPMENT

Public transport has been promoted world-wide to address climate change by reducing auto emissions, for social and health benefits related to walking and for catalyzing economic development. These benefits are based on a combination of supportive urban form that puts the people that will take public transport within close proximity to stations. Many of these environmental and physical health benefits are based on agglomeration and density, from compact living connected by lines of public transport. The research presented in this paper from a comparative site and the statistical analysis of census data found that in Los Angeles County, passenger rail ridership was correlated with lower income users. However, there are many tensions between new passenger rail stations, catalytic economic uplift, that gentrifies an area and pushes out the very people that would use public transport. While the Los Angeles County Metropolitan Transportation Authority is dependent on low income riders for financial success and the return of positive environmental and public health benefits, new stations developments are part of a phenomenon of gentrification, pricing out public transport users. This key challenge is diagnosed in this paper arguing that in order to be successful, public transport agencies must adapt the built environment as well as supplying new transport routes, providing affordable housing for their riders in close proximity to stations, so that the people that will use public transport, can.
Segmentation of Gliomas using GLCM Features and Classification of Gliomas in Brain using SVM Classifier

Brain Gliomas is one among the biggest threat faced by many people around the globe. According to International Agency of Research on Cancer (IARC) more than one million people are diagnosed with brain gliomas per year around the globe, with increased fatal rate. During its studies, the occurrence of the abnormal tissues is simple to detect most of the time; still accurate segmentation and characterization of these abnormalities are not genuine. In the present situation, radiologists have to manually study the reports with the available medical imaging machines and write a report. This process is time consuming. In fact that, numerous advancement being done, butsegmentation of brain gliomas from MR Images in a rapid, accurate, legitimate and far sighted way is still a demanding role. To overcome this situation a system which can detect the gliomas and will differentiate them as gliomas and non-gliomas has been proposed in this project by using image processing in addition with machine learning, which will help to detect the gliomas and classify them into gliomas or non-gliomas in no time. In this approach, stage by stage techniques for image pre-processing, segmenting brain gliomas using morphological operations, retrieval of gliomas feature using contrast and correlation, classification of the gliomas using SVM is completed with the actual clinical data.
Non-Zero Degree Maps Between 2n-Manifolds

Thorn-Pontrjagin constructions are used to give a computable necessary and sufficient condition for a homomorphism φ：H^n(L：Z)→H^n(M：Z)to be realized by a map f:M→L of degree k for closed(n-1)-connected 2n-manifoldsM and L，n>1. A corollary is that each(n-1)-connected 2n-manifold admits selfmaps of degree larger than l，n>1. In the most interesting case of dimension 4． With the additional surgery arguments we give a necessary and sufficient condition for the existence of a degree k map from a closed orientable 4-manifold M to a closed simply connected 4-manifold L in terms of their intersection forms；in particular，there is a map f：M→L of degree 1 if and only if the intersection form of L is isomorphic to a direct summand of that of M。
D EEP R ETRIEVAL : A N E ND - TO -E ND S TRUCTURE M ODEL FOR L ARGE -S CALE R ECOMMENDATIONS

One of the core problems in large-scale recommendations is to retrieve top relevant candidates accurately and efficiently, preferably in sub-linear time. Previous approaches are mostly based on a two-step procedure: first learn an inner-product model and then use maximum inner product search (MIPS) algorithms to search top candidates, leading to potential loss of retrieval accuracy. In this paper, we present Deep Retrieval (DR), an end-to-end learnable structure model for largescale recommendations. DR encodes all candidates into a discrete latent space. Those latent codes for the candidates are model parameters and to be learnt together with other neural network parameters to maximize the same objective function. With the model learnt, a beam search over the latent codes is performed to retrieve the top candidates. Empirically, we showed that DR, with sub-linear computational complexity, can achieve almost the same accuracy as the brute-force baseline.
Sequential Study of 7-Glutamyltransferase during Complete and Two-Stage Mouse Skin Carcinogenesis1

The histochemical pattern of 7-glutamyltransferase (GGT) was studied in benign and malignant tumors produced by two differ ent experimental protocols, two-stage carcinogenesis and com plete carcinogenesis. Six percent of all papillomas produced by two-stage carcinogenesis were GGT positive, whereas 14% of benign tumors produced by complete carcinogenesis exhibited GGT-positive areas. The incidence of GGT-positive papillomas in the two-step carcinogenesis protocol increased up to wk 28 of treatment. After 32 wk, the incidence decreased abruptly, coinciding with an abrupt increase in the incidence of squamous cell carcinomas. On the other hand, the incidence of GGT-positive benign tumors produced during the course of complete carcinogenesis increased gradually up to wk 32 of treatment, coinciding with the increased incidence of squamous cell carcinomas. The inci dence of GGT-positive keratoacanthomas and GGT-positive pap illomas produced with the complete carcinogenesis protocol exhibited different patterns, suggesting different histogenesis and biological behavior of these two types of tumors. In addition, the labeling index of GGT-positive areas was lower (17 Â±3%) than that of the GGT-negative areas (41 Â±0.18%) of the same papillomas, indicating that the presence of GGT may be related to abnormal keratocyte differentiation rather than to proliferative changes.
Practice of Epidemiology A Simple Unified Approach for Estimating Natural Direct and Indirect Effects

An important problem within both epidemiology and many social sciences is to break down the effect of a given treatment into different causal pathways and to quantify the importance of each pathway. Formal mediation analysis based on counterfactuals is a key tool when addressing this problem. During the last decade, the theo-retical framework for mediation analysis has been greatly extended to enable the use of arbitrary statistical models for outcome and mediator. However, the researcher attempting to use these techniques in practice will often find implementation a daunting task, as it tends to require special statistical programming. In this paper, the authors introduce a simple procedure based on marginal structural models that directly parameterize the natural direct and indirect effects of interest. It tends to produce more parsimonious results than current techniques, greatly simplifies testing for the presence of a direct or an indirect effect, and has the advantage that it can be conducted in standard software. However, its simplicity comes at the price of relying on correct specifica-tion of models for the distribution of mediator (and exposure) and accepting some loss of precision compared with more complex methods. Web Appendixes 1 and 2, which are posted on the Journal ’ s Web site (http://aje. oupjournals.org/), contain implementation examples in SAS software (SAS Institute, Inc., Cary, North Carolina) and R language (R Foundation for Statistical Computing, Vienna, Austria). MSM,
This information is current as Predisposes to Ascending Bacterial Infection Viral Infection of the Pregnant Cervix

Preterm birth is the major cause of neonatal mortality and morbidity, and bacterial infections that ascend from the lower female reproductive tract are the most common route of uterine infection leading to preterm birth. The uterus and growing fetus are protected from ascending infection by the cervix, which controls and limits microbial access by the production of mucus, cytokines, and antimicrobial peptides. If this barrier is compromised, bacteria may enter the uterine cavity, leading to preterm birth. Using a mouse model, we demonstrate, to our knowledge for the ﬁrst time, that viral infection of the cervix during pregnancy reduces the capacity of the female reproductive tract to prevent bacterial infection of the uterus. This is due to differences in susceptibility of the cervix to infection by virus during pregnancy and the associated changes in TLR and antimicrobial peptide expression and function. We suggest that preterm labor is a polymicrobial disease, which requires a multifactorial approach for its prevention and treatment. The Journal of Immunology , 2013, 191: 000–000.
Smith ScholarWorks Smith ScholarWorks De novo Sequencing, Assembly, and Annotation of the De novo Sequencing, Assembly, and Annotation of the Transcriptome for the Free-Living Testate Amoeba Transcriptome for the Free-Living Testate Amoeba Arcella Arcella intermedia intermedia

Arcella , a diverse understudied genus of testate amoebae is a member of Tubulinea in Amoebozoa group. Transcriptomes are a powerful tool for characterization of these organisms as they are an efﬁcient way of characterizing the protein-coding potential of the genome. In this work, we employed both sin-gle-cell and clonal populations transcriptomics to create a reference transcriptome for Arcella . We compared our results with annotations of Dictyostelium discoideum , a model Amoebozoan. We assembled a pool of 38 Arcella intermedia transcriptomes, which after ﬁltering are composed of a total of 14,712 translated proteins. There are GO categories enriched in Arcella including mainly intracellular signal transduction pathways; we also used KEGG to anno-tate 11,546 contigs, which also have similar distribution to Dictyostelium . A large portion of data is still impossible to assign to a gene family, probably due to a combination of lineage-speciﬁc genes, incomplete sequences in the transcriptome and rapidly evolved genes. Some absences in pathways could also be related to low expression of these genes. We provide a reference database for Arcella, and we highlight the emergence of the need for further gene discovery in Arcella.