Miracle-dz/UniFAR-FTUs huggingface dataset:
A COMPUTATIONAL GENOME ANALYSIS OF STRAIN BACILLUS SUBTILIS MIZ-8 ISOLATED FROM BEKANG REVEALS A DISTINCT CHROMOSOME AND PLASMID CONFERRING SELECTIVE ADVANTAGE

Bacillus subtilis Miz-8 is isolated from Bekang, a traditional fermented soybean food of Mizoram, India. Here, we report computationally analyzed strain Miz-8 mapped to the annotated genome of the reference strain Bacillus subtilis subsp. natto BEST195. Miz-8 has a circular chromosome and a small plasmid with genome size of 4105264 bp and 5838 bp, respectively. Genome contains the genes responsible for synthesis of biosynthetic metabolites like surfactin, fengycin, bacillibactin, bacilysin, subtilosin A and alpha amylase production. The strain Miz-8 harbored virulence genes identical to the strain BEST195 render themselves harmless for human consumption. However, Strain Miz-8 has one intact prophage region but no integrase protein, making it incapable of lateral transfer of antimicrobials. Antibiotic resistance genes were predicted among which tmrB gene was on perfect hit. Plasmid of strain Miz-8 contains no prophage sequences and antibiotic resistance genes. Furthermore, there were several single nucleotide polymorphisms and 344 insertion-deletion polymorphisms. Bacillus subtilis Miz-8's genomic information unmasks its functional significance on human health.
Condiciones laborales de los inmigrantes en la Unión Europea: un estudio comparado

It is necessary to analyze the phenomenon of immigration to understand the development and recent evolution of the European Union. However, studies on this subject are scarce and of a very limited scope due, among other reasons, to the difficulty of obtaining reliable and consistent information. The aim of this paper is precisely to analyse immigrant populations in the context of the European Union, and examine one of the most controversial aspects of this phenomenon: the integration of these individuals into the labour market. Using a logistic regression model �applied to the last Survey on European Working Conditions that was carried out in all 25 EU countries� we evaluate the working conditions of the immigrant population as compared to those of native workers.
Prevalence of antibiotic-resistant Gram-negative bacteria having extended-spectrum β-lactamase phenotypes in polluted irrigation-purpose wastewaters from Indian agro-ecosystems

Antibiotic resistance in bacteria has emerged as a serious public health threat worldwide. Aquatic environments including irrigation-purpose wastewaters facilitate the emergence and transmission of antibiotic-resistant bacteria and antibiotic resistance genes leading to detrimental effects on human health and environment sustainability. Considering the paramount threat of ever-increasing antibiotic resistance to human health, there is an urgent need for continuous environmental monitoring of antibiotic-resistant bacteria and antibiotic resistance genes in wastewater being used for irrigation in Indian agro-ecosystems. In this study, the prevalence of antibiotic resistance in Gram-negative bacteria isolated from irrigation-purpose wastewater samples from Sirmaur and Solan districts of Himachal Pradesh was determined. Bacterial isolates of genera Escherichia, Enterobacter, Hafnia, Shigella, Citrobacter, and Klebsiella obtained from 11 different geographical locations were found to exhibit resistance against ampicillin, amoxyclav, cefotaxime, co-trimoxazole, tobramycin, cefpodoxime and ceftazidime. However, all the isolates were sensitive to aminoglycoside antibiotic gentamicin. Enterobacter spp. and Escherichia coli showed predominance among all the isolates. Multidrug-resistance phenotype was observed with isolate AUK-06 (Enterobacter sp.) which exhibited resistant to five antibiotics. Isolate AUK-02 and AUK-09, both E. coli strains showed resistant phenotypes to four antibiotics each. Phenotypic detection revealed that six isolates were positive for extended-spectrum β-lactamases which includes two isolates from Enterobacter spp. and E. coli each and one each from Shigella sp. and Citrobacter sp. Overall, the findings revealed the occurrence of antibiotic resistant and ESBL-positive bacterial isolates in wastewaters utilized for irrigation purpose in the study area and necessitate continuous monitoring and precautionary interventions. The outcomes of the study would be of significant clinical, epidemiological, and agro-environmental importance in designing effective wastewater management and environmental pollution control strategies.
Shelf-life Assessment of Tulsi and Stevia Incorporated Low Sugar Kadaknath Egg Jam

The study was conducted during from September–January, 2020–2021 in the department of Livestock Products Technology, college of veterinary science and animal husbandry, Mhow, Madhya Pradesh, India. The Kadaknath egg jam was developed to increase nutritional content and decrease sugar content, jam with 1% tulsi and stevia was found suitable and most acceptable by sensory panelists. Hence, selected for further storage stability under refrigeration. TBA, FFA value and microbial count of values for control jam were non-significantly (p<0.05) lower as compared to developed tulsi incorporated low sugar kadaknath egg jam throughout the entire storage. A progressive and significant (p<0.05) increased in the TBA and FFA values of control as well as developed tulsi incorporated kadaknath egg jam observed with advancement of storage. The total plate count (TPC) followed a steadily significantly (p<0.05) increasing pattern from 0–15 day in control as well as developed tulsi incorporated low sugar kadaknath egg jam. Psychrotropic counts as well as Yeast and Mold count were not detected on 10 and 15 day of storage respectively in both control and as well as developed tulsi incorporated low sugar kadaknath egg jam. Coliform were not detected during the entire period of storage in both control as well as developed tulsi incorporated low sugar kadaknath egg jam. The observation indicated that microbial count and rancidity level as well as sensory attributes remained well below the permissible level and product was stable up to 15 days of storage under refrigeration (4±1oC).
Effectiveness Of Double J Stent With Extracorporeal Shockwave Lithotripsy: An Analysis Of Stone-Free Rates

Introduction: Preservation of renal function and integrity is of profound importance and therefore renders stent-related symptoms a secondary concern. The usage of DJ stent is known for decades to support stone removal, this study aims to assess the effect of DJ stent after extracorporeal shock wave lithotripsy for stone removal and DJ stent-related complications in adult patients. Methods: This is a prospective, comparative study, Patients were selected after being diagnosed with established radiological evidence of a single radio-opaque stone ≤ 2 cm. The presence of the visible radio-opaque shadow post-procedure indicated residual stones and negative results. Primary follow-up was recommended after 2 weeks post-procedure and participants were inquired about all the anticipated complications, data was entered on SPSS version 23.0 for analysis. The chi-square test was applied to assess the significance and a p-value ≤ 0.05 was deemed significant for our results. Results: The sample size of the study was 150, sorted equally into two separated groups categorized by presence and absence of DJ stent after ESWL, stone size was almost similar to avoid any confounding factor with the mean value of 1.24 ± 0.2 in group A and 1.6 ± 0.1 in group B, with a p-value of 0.05. Hematuria was categorized within mild 6(4%) & 7(4.6%), moderate 6(4%) & 5(3.3%) while gross hematuria was reported in 1(0.6%) & 2(1.3%) in group A and B respectively. Conclusion: This study concluded that using a DJ stent with ESWL does not help in the stone passage or improve stone-free rates of stone removal after breaking the calculi with shockwave lithotripsy.
Design and Performance Analysis of Voltage-Controlled Oscillator

In this paper, a 3-stage PG-ring VCO is designed using a power gating technique in cadence virtuoso and 180nm technology. Here, the efficiency of a 3-stage PG-ring VCO is evaluated by comparing its performance to that of other VCOs. Power gating techniques are utilized to reduce circuit leakage. The analysis is conducted using various design techniques and transistor sizes. It has been observed that a 3-stage PG-ring oscillator offers better performance in terms of various metrics, including power, frequency, energy, and power delay transistor count product (PDNP), with transistor dimensions.
Multi-dimensional parameter estimation of uniform circular array electromagnetic vector sensor based on polarization-direction of arrival matrix

Abstract. Uniform circular array electromagnetic vector sensor (UCA-EVS) can provide omni-directional and high-resolution azimuth information and polarization information, which has been widely concerned in the field of radar signal processing. Aiming at the joint estimation of direction of arrival (DOA) and polarization parameters of coherent sources via UCA-EVS, a multi-dimensional parameter estimation method with low complexity—polarization-DOA matrix method—is proposed. First, the rank of array covariance matrix is recovered by axial virtual translation, and then the direction and polarization parameters of the signal are estimated by using the eigenvalues and eigenvectors of the matrix based on constructing polarization-DOA matrix. Different from the traditional DOA matrix method, the proposed algorithm can not only estimate the azimuth information of the signals but also provide the polarization information of the targets, and the estimated parameters can be matched automatically. At the same time, it can estimate the parameters only by using the information of three elements, which can save hardware resources. In addition, the proposed method does not need to search for spectral peaks, which not only greatly reduces the computational complexity but also loses the estimation accuracy. Simulation results verify the feasibility of the proposed algorithm.
Evaluation of Biomass Burning in China Using Satellite Remote Sensing Data [an abstract of dissertation and a summary of dissertation review]

Title Evaluation of Biomass Burning in China Using Satellite Remote Sensing Data [an abstract of dissertation and a summary of dissertation review] Author(s) 伊, 坤朋 Citation 北海道大学. 博士(農学) 甲第11499号 Issue Date 2014-06-30 Doc URL http://hdl.handle. net/2115/56696 Rights(URL) http://creativecommons.org/licenses/by-nc-sa/2.1/jp/ Type theses (doctoral abstract and summary of review) Additional Information There are other files related to this item in HUSCAP. Check the above URL. File Information Yi_Kunpeng_review. pdf (審査の要旨)
The population dynamics of Nepal

Drawing upon censuses survey reports and other data sources including information from the 1976 Nepal Fertility Survey this paper analyzes the demographic situation of Nepal within the broader context of recent economic agricultural and environmental changes. Over the period examined from the early 1950s to the late 1970s fertility has remained high. Mortality though still high has begun a gradual decline and a trend toward lower infant mortality is evident. A trend toward later marriage is also underway although it has not been sufficient to depress fertility. Nepal has had a national family planning program for over a decade but knowledge and use of modern contraceptive methods overall are still at a very low level. Despite the governments efforts to provide family planning services throughout the country inaccessibility of many rural villages remains an obstacle. Nepals isolation and mountainous topography have impeded other forms of modernization as well. The countrys predominantly agricultural economy has barely kept up with population increase in recent years. Per hectare agricultural yields have actually declined and increases in total agricultural production have come almost exclusively from the expansion of tilled acreage. The combination of rapid population growth declining agricultural productivity and reliance on wood as a fuel has resulted in deforestation and consequent soil erosion floods and landslides. 1 response to the dilemma of increasing population pressure declining agricultural productivity and deterioration of the environment has been accelerated population redistribution mainly from the hills and mountains to the terai (lowland plains) where malaria was brought under control during the 1950s. The majority of migrants are male attracted to the prospect of acquiring terai land. Because the country has not yet experienced much urbanization rural-to-rural migration is the predominant redistribution process although international migration between Nepal and neighboring countries in particular India continues to be substantial. Because of declining mortality and sustained high fertility Nepal is likely to experience continued rapid population growth in the immediate future. The demographic momentum inherent in the young age structure of the population will result in a population of over 20 million by the end of this century. For a small mountainous country with already high population density on the arable land and a modest known resource base such growth will pose major economic social and ecological problems. (authors)
Predatory Bacteria: A Novel Approach to Antibiotic Substitution

Antibiotics are an effective means of treating infectious bacterial diseases. However, the extensive use of antibiotics in the recent past has resulted in antibiotic-resistant bacteria which interfere with disease treatment and recovery. There is an urgent need for novel medicines to treat Gram-negative infections because there are not enough antibiotics in development to address projected and present demands. One novel approach to antibiotic alternatives is the use of living predatory bacteria which can naturally prey upon other Gram-negative bacteria. These predators are ubiquitous in a wide variety of manmade and natural environments and depending upon their feeding habits are classified as obligatory or facultative predators. All the obligate predators are classified under the umbrella terminology Bdellovibrio and like organisms (BALOs). Bdellovibrio bacteriovorus is by far the most studied BALOs and have long been recognized as a potential therapeutic, water clean-up, and biocontrol agent and source for discovering novel biotechnological tools for research. Antibiotics won’t be replaced by pills containing predatory microorganisms any time soon. However, understanding these bacteria could help us prepare for a time when many medications cannot treat infections that are multi-drug resistant. A paradigm change is necessary since it may appear counterintuitive to cure a bacterial infection by giving another bacterium. The burden of an infection on the host must be taken into account while evaluating the prospective implications of treating a Gram-negative bacterial infection with the administration of a live predatory bacterium.
The role and challenges of governments in promoting sustainable development

This paper provides a review of the existing research on governments’ role towards sustainable development. The paper applies a literature review method and focuses first on general issues of sustainable development, followed by a more in-depth review on governments’ role in promoting sustainability. Finally, the study addresses the assessment of governments’ challenges and proposes actions towards sustainable goals. The paper also highlights the connection between sustainability and sustainable development. This study finds that governments are the main actors that can create and successfully promote a sustainable society. Governments, however, face many challenges in attempting to achieve this goal. One of the main challenges is the coordination between different actors that are part of the implementation of SDGs. These obstacles are of environmental, social, economic, and institutional in nature. Yet, governments are one of the main driving forces that organize and motivate all other responsible factors in promoting a sustainable society. Regardless of the enormous attention in academia towards sustainability and sustainable development, studies on governments’ role and challenges towards SDGs are still limited. In this context, this paper provides an overview of the role of governments in sustainable development, and it also describes the challenges to be overcome in achieving sustainable goals. Finally, suggestions on future research areas are presented.
Beyond-mean-field description of octupolarity in dysprosium isotopes with the Gogny-D1M energy density functional

The emergence and stability of (static) octupole deformation effects in Dy isotopes from dripline to dripline ($72 \le N \le 142$) is analyzed in this paper using mean-field and beyond-mean-field techniques often used for this purpose. We find static octupole deformations at the Hartree-Fock-Bogoliubov (HFB) level with the Gogny D1M force for $N \approx 134$ isotopes, while nuclei with $N \approx 88$ exhibit reflection-symmetric ground states. It is shown that, given the softness found in the mean-field and parity-projected potential energy surfaces along the octupole direction, neither of these two levels of approximation is suficcient to extract conclusions about the (permanent and/or vibrational) nature of octupole dynamic in Dy isotopes. From the analysis of the collective wave functions as well as the excitation energies of the first negative-parity states and $B(E3)$ strengths, obtained within the framework of a two-dimensional symmetry-conserving generator coordinate method (2D-GCM), it is concluded that the increased octupole collectivity in Dy isotopes with $N \approx 88$ and $N \approx 134$ is a vibrational-like effect that is not directly related to permanent mean-field octupole deformation in the considered nuclei. A pronounced suppression of the $B(E1)$ strengths is predicted for isotopes with $N \approx 82$ and $N \approx 126$. The comparison of results obtained with other parametrizations, show the robustness of the predicted trends with respect to the underlying Gogny energy density functional.
2D and 1D numerical model simulations for the effect of a single detached breakwater on the shore

The developmeot of the coastal area is oeeded for tourism and commercial purposes for a country located nearby a coast. Coastal development may lead to local erosion of the shoreline. Coastal defence structures, like an offshore breakwaters, may be used to solve tbis problem. An offshore breakwater is a breakwater parallel to the shore and located at aspecific distance form the original shoreline. To understand the influence of the breakwater on the hydrodynamic processes as well as on the morphological evolution, physical models or mathematical models are developed. The mathematical models do not suffer from the scale effect. In this study, a morphodynamic model DELFI'2D-MOR, which is a two-dimensional horizootal model, and an ooe-line model UNIBEST have been used. The DELFI'2D-MOR model is a coupled model system which coosists of four modules. The four modules are the wave module (lllSW A), the flow module (TRISULA), the transport module and the bottom module. A sensitivity analysis is made to investigate the impact of the offshore breakwater geometry on the hydrodynamic processes and the morphological evolutions. It was found that the breakwater geometry affects the hydrodynamic processes as well as the morphological evolution (salient or tombolo). Based on sensitivity analysis, the wave-current interaction was found to affect the morphological evolutions. The agreement between the results of the model and the literature results was quite satisfactory. After getting insight in the validity of the DELFI'2D-MOR model, a case study of a single detached breakwater situated at the northern coast of Egypt was carried out. The wave elimate was analyzed to get the morphological equivalent one-wave condition and two-wave condition. The choice of the bottom roughness in the one-wave condition simulation appeared to affect the hydrodynamic processes and the morphological evolutions. Applying the twowave condition in the 2D-computations gave a step forward for the morphological computations in which the two-wave condition simulation gave more authentic results than the one-wave condition simulation. The choice of the wave-current induced shear stress appeared to affect the hydrodynamic processes in the 2D-model. The results of wave, longshore current and the sediment transport in the UNIBEST model are compared to the 2D-model results. It was found that the longshore current was higher due to the longshore current formulation used in the UNIBEST model. This in turn affects the sediment transport rate. Tombolo formation can not be simulated in the UNIBEST model for a case with normally incident waves since the effects of the circulation cells are not taken into account. However, it can be simulated for a case with obliquely incident waves.
Bringing In-Sensor Intelligence in Radiation Detectors: a Short Review

Technological trends, challenges and solutions recently proposed in the literature to embed intelligence, in particular machine learning, into solid-state sensors and radiation detectors are discussed. Starting from the paradigms adopted in low-power wearable devices for local, real-time processing of medical signals such as System-on-Chip and System-in- Package, we will move to the case of solid-state radiation detectors readout by multichannel application specific integrated circuits (ASIC). Here, special focus is devoted to analog solutions which hold potential for radical reduction of power dissipation and interconnection lines (and data throughput) between the detector head and the acquisition back-end. We present the concept of a CMOS analog implementation of an artificial neural network, fusible with the detector analog front-end circuit, for instance for gamma cameras and we compare it with novel ADC-less approaches emerging in the field.
kLa based scale-up cultivation of the extremophilic archaeon Sulfolobus acidocaldarius: from benchtop to pilot scale

The two major scale-up criteria in continuously stirred bioreactors are 1) constant aerated power input per volume (Pg/Vl), and 2) the volumetric O2 mass transfer coefficient (kla). However, Pg/Vl is only influenced by the stirrer geometry, stirrer speed, aeration and working volume, while the kla is additionally affected by physiochemical properties of the medium (temperature, pH, salt content, etc.), sparging of gas and also by the bioreactor design. The extremophilic archaeon Sulfolobus acidocaldarius, thriving at 75°C and pH 3.0, has the potential for many biotechnological applications. However, previous studies imply that the family Sulfolobaceae might be affected by higher oxygen concentration in the headspace (>26%). Hence, adequate oxygen supply without being toxic has to be ensured throughout the different scales. In this study, the scale-up criteria Pg/Vl and kla were analyzed and compared in a 2 L chemostat cultivation of S. acidocaldarius on a defined growth medium at 75°C and a pH value of 3.0, using two different types of spargers at the same aerated power input. The scale-up criterion kLa, ensuring a high specific growth rate as well as viability, was then used for scaleup to 20 L and 200 L. By maintaining a constant kla comparable dry cell weight, specific growth rate, specific substrate uptake rates and viability were observed between all investigated scales. This procedure harbors the potential for further scale-up to industrial size bioreactors.