Miracle-dz/UniFAR-FTUs huggingface dataset:
Soft-x-ray spectra of krypton xxiv–xxvii in gas puff Z-pinch plasmas

The spectra of krypton ions produced by the magnetic implosion of a krypton gas cylinder in the wavelength range from 10 to 250 A have been observed. Lines from highly ionized krypton ions from Kr xxiv to Kr xxvii have been identified by isoelectronic sequence extrapolation and compared with ab initio relativistic calculations. Energy levels are derived for Kr xxvi.
Wave Dispersion in a Two-Phase Gas Mixture : Comments on Random Motions and Void Modes

The properties of linear waves in a mixture comprising diffuse and dense phases are discussed using two approaches: (i) In one approach, the repulsive pressure produced in the diffuse phase by ballistically moving dense clouds generates motion of the components when gradients of the volume-filling factor arise; (ii) in the other approach, where this effect is omitted, a mixture is dynamically insensitive to perturbations containing only variations in the volume-filling factor of dense clouds. We show that the wave dynamics in these two approaches is quite different: in the framework of the first approach, the dispersion relation contains two different branches — the acoustic and the void (pattern formation) modes, while in the second approach the void mode disappears. We argue that in most situations for astrophysical gas mixtures, the first approach is more applicable: since effects of repulsive pressure from randomly moving clouds do exist, the void mode must be important in determining the dynamics of small perturbations and the formation of structures.
PRICING OF EXOTIC ENERGY DERIVATIVES BASED ON ARITHMETIC SPOT MODELS

Based on a non-Gaussian Ornstein–Uhlenbeck model for energy spot, we derive prices for Asian and spread options using Fourier techniques. The option prices are expressed in terms of the Fourier transform of the payoff function and the characteristic functions of the driving noises, being independent increment processes. In many relevant situations, these functions are explicitly available, and fast Fourier transform can be used for efficient numerical valuation. The arithmetic nature of our model implies that only a one-dimensional Fourier transform is required in the computation of the price, contrary to geometric models where transformation along both underlying variables is necessary.
Theory of Nonadiabatic Superconductivity

All high-temperature superconductors (and especially the C60 compounds) are characterized by a small Fermi energy (EF), of the order of the maximum phonon frequency (? D). We generalize therefore the many-body theory of superconductivity to the nonadiabatic case (? D/EF? 0). This implies the breakdown of Migdal's theorem and it requires the inclusion of vertex renormalization and higher-order diagrams in the self-consistent gap equation. We show that these nonadiabatic effects produce a strong enhancement of Tc with respect to the usual theory (McMillan). The observed values of Tc for the C60 compounds and for the cuprates can be naturally obtained within the present theory with normal values for the electron-phonon coupling ? In addition we predict an anomalous behaviour for the isotope effect.
Hall parameters of complete and complete bipartite graphs

Given a graph G, for each υ ∈V(G) let L(υ) be a list assignment to G. The well‐known choice number c(G) is the least integer j such that if |L(υ)| ≥j for all υ ∈V(G), then G has a proper vertex colouring ϕ with ϕ(υ) ∈ L (υ) (∀υ ∈V(G)). The Hall number h(G) is like the choice number, except that an extra non‐triviality condition, called Hall's condition, has to be satisfied by the list assignment. The edge‐analogue of the Hall number is called the Hall index, h′(G), and the total analogue is called the total Hall number, h″(G), of G. If the stock of colours from which L(υ) is selected is restricted to a set of size k, then the analogous numbers are called k‐restricted, or restricted, Hall parameters, and are denoted by hk(G), h′k(G) and h″k(G).
Role of Topical Ritodrine Hydrochloride in Experimentally Induced Hypertrophic Scar in Rabbits

Hypertrophic scars are fibroproliferative illnesses caused by improper wound healing, during that, excessive inflammation, angiogenesis, and differentiated human dermal fibroblast (HDF ) function contribute to scarring, whereas hyperpigmentation negatively affects scar quality. Over 100 million patients heal with a scar every year. To investigate the role of the beta 2 adrenergic receptor (β2AR); Ritodrine, in wound scarring, the ability of beta 2 adrenergic receptor agonist (β2ARag) to alter HDF differentiation and function, wound inflammation, angiogenesis, and wound scarring was explored in HDFs, zebrafish, chick chorioallantoic membrane assay (CAM), and a porcine skin wound model, respectively. A study identify a β2AR-mediated mechanism for scar reduction. β2ARag significantly reduced HDF differentiation, via multiple cAMP and/or fibroblast growth factor 2 or basic FGF (FGF2)-dependent mechanisms, in the presence of transforming growth factor betaβ1, reduced contractile function, and inhibited mRNA expression of a number of profibrotic markers. β2ARag also reduced inflammation and angiogenesis in zebrafish and CAMs in vivo, respectively. In Red Duroc pig full-thickness wounds, β2ARag reduced both scar area and hyperpigmentation by almost 50% and significantly improved scar quality. Indeed, mechanisms delineated in vitro and in other in vivo models were evident in the β2ARag-treated porcine scars in vivo. Both macrophage infiltration and angiogenesis were initially decreased, whereas DF function was impaired in the β2ARag-treated porcine wound bed. This data reveal the potential of β2ARag to improve skin scarring. The purpose of this study was to assess the therapeutic effect of topical Ritodrine hydrochloride on hypertrophic scars in rabbits. Thirty-two healthy male albino rabbits that divided in to 4 groups were included in the study (healthy; induced untreated hypertrophic scars; induced hypertrophic scars treated with 0.1% Triamcinolone acetonide (TAC) as a standard drug; and induced hypertrophic scars treated with 0.5% Ritodrine HCL gel twice daily for 21 days. Histopathology of skin sections, transforming growth factor beta1 TGFβ-1 level, and collagen III alpha1 in skin tissue were all used as outcome measures. Compared to the induced hypertrophic scar group; treatment with Ritodrine significantly reduced means of TGF β1 and collagen III (p ≤0.01); significantly reduce mean score of inflammation (p ≤0.001), significantly lowered scar size (P ≤ 0.001), and significantly lower mean scar height (P≤0.001), but no significant decrease in SEI (P>0.05). Therapy of induced hypertrophic scar with topical Ritodrine was successfully effective in rabbits. It reduced the immunological score (TGF-β1, collagen III), inflammation, and scar size in a substantial way. This effect was comparable (except in terms of SEI) to topical Triamcinolone acetonide efficacy
Measurement Points Registration for Hull Blocks Based on Multi-objective Optimization ⋆

In shipbuilding accuracy control, the following problem is encountered. The measurement points are matched with design points manually with the engineering constraints not being considered. Thus the matching results are sometimes not reasonable. To solve this problem, this article presents an automatically matching algorithm for hull block based on multi-objective optimization. Principal Component Analysis (PCA) is applied to narrow the dislocation between measurement points and design points. Then the pair-wise points are initially matched by Iterative Closest Point (ICP). Engineering constraints are added to the objective function of the multi-objective optimization model. The error distribution is determined by setting weight vectors which control the constraints. The experimental results prove that the proposed algorithm can obtain the most reasonable matching result automatically which meets the engineering constraints. It can reasonably evaluate the error information of instruction thereby provide an instructive basis for subsequent assembly.
The effects of Kelvin-Helmholtz instability on resonance absorption layers in coronal loops

One of the long-standing uncertainties in the wave-resonance theory of coronal heating is the stability of the resonance layer. The wave motions in the resonance layer produce highly localized shear flows which vary sinusoidally in time with the resonance period. This configuration is potentially susceptible to the Kelvin-Helmholtz instability (KHI), which can enhance small-scale structure and turbulent broadening of shear layers on relatively rapid ideal timescales. We have investigated numerically the response of a characteristic velocity profile, derived from resonance absorption models, to finite fluid perturbations comparable to photospheric fluctuations. We find that the KHI primarily should affect long (approximately greater than 6 x 10(exp 4) km) loops where higher velocity flows (M approximately greater than 0.2) exist in resonance layers of order 100 km wide. There, the Kelvin-Helmholtz growth time is comparable to or less than the resonance quarter-period, and the potentially stabilizing magnetic effects are not felt until the instability is well past the linear growth stage. Not only is the resonance layer broadened by the KHI, but also the convective energy transport out of the resonance layer is increased, thus adding to the efficiency of the wave-resonance heating process. In shorter loops, e.g., those in bright points and compact flares, the stabilization due to the magnetic field and the high resonance frequency inhibit the growth of the Kelvin-Helmholtz instability beyond a minimal level.
Berbamine Hydrochloride Inhibits African Swine Fever Virus Infection In Vitro

African swine fever virus (ASFV) causes a viral disease in swine with a mortality rate of approximately 100%, threatening the global pig industry’s economic development. However, vaccines are not yet commercially available, and other antiviral therapeutics, such as antiviral drugs, are urgently needed. In this study, berbamine hydrochloride, a natural bis-benzylisoquinoline alkaloid isolated from the traditional Chinese herb Berberis amurensis, showed significant antiviral activity against ASFV. The 50% cytotoxic concentration (CC50) of berbamine hydrochloride in porcine alveolar macrophages (PAMs) was 27.89 μM. The antiviral activity assay demonstrated that berbamine hydrochloride inhibits ASFV in a dose-dependent manner. In addition, a 4.14 log TCID50 decrease in the viral titre resulting from non-cytotoxic berbamine hydrochloride was found. Moreover, the antiviral activity of berbamine hydrochloride was maintained for 48h and took effect at multiplicities of infection (MOI) of 0.01, 0.1, and 1. The time-of-addition analysis revealed an inhibitory effect throughout the entire virus life-cycle. A subsequent viral entry assay verified that berbamine hydrochloride blocks the early stage of ASFV infection. Moreover, similar anti-ASFV activity of berbamine hydrochloride was also found in PK-15 and 3D4/21 cells. In summary, these results indicate that berbamine hydrochloride is an effective anti-ASFV natural product and may be considered a novel antiviral drug.
Algorithm for Determining Most Reliable Travel Time Path on Network with Normally Distributed and Correlated Link Travel Times

Transportation networks are subject to significant travel time uncertainty as a result of traveler behavior, recurring congestion, capacity variability (construction zones, traffic incidents), variation in demand, and so on. Therefore, interest is growing in modeling and optimizing travel time reliability in such networks. This paper proposes an efficient algorithm to compute the path of maximum travel time reliability on a network with normally distributed and correlated link travel times. For this optimal reliability path (ORP) problem, it is shown that the subpath optimality condition for the deterministic shortest path problem does not hold, and consequently, a new bounds-based optimality criterion is proposed using the K shortest expected time paths and the minimum path variance on the network. An algorithm is developed to solve the ORP problem on the basis of the proposed optimality criterion and an efficient path generation procedure. Computational experiments on various test networks show the proposed algorithm to be efficient, requiring limited path enumeration. With as few as five shortest paths and 50 Monte Carlo draws, the proposed algorithm is able to find the most reliable path for realistic network sizes. Empirical investigations highlight the unreliability of the least expected time path and suboptimality of the independence assumption. The study also underscores the role of risk attitudes (reflected by reliability threshold) on the benefits of the ORP. The algorithm and empirical results have important applications for developing reliability-based routing applications for congestion mitigation and intelligent transportation systems.
Treadmill Exercise as a Preventive Measure Against Age-Related Anxiety and Social Behavioral Disorders in Rats: When Is It Worth Starting?

Objective To determine the appropriate time points to start regular exercise which could reduce age-related anxiety and impaired social behavior. Methods For this study, 8-week-old male Wistar rats were divided into three groups: no exercise (NoEX), short-term exercise (S-Ex), and long-term exercise (L-Ex) groups. S-Ex-group rats started treadmill exercise at 12 months of age, while L-Ex rats started from at 2 months of age. Exercise rats were forced to walk on the treadmill three times per week, with 1- to 2-day intervals for 10 minutes during the first 2 weeks, at 10 m/min until 17 months of age, and at 8 m/min thereafter. At 19 months of age, behavioral tests were performed to assess the effects of exercise on age-induced behavioral change as well as quantitative polymerase chain reaction were done to uncover the mechanism behind the behavioral changes. Results Anxiety-like behavior was improved by long-term exercise. Additionally, rats belonging to the S-Ex and L-Ex groups showed improved social behavior and increased curiosity about interesting objects. The qPCR data showed that treadmill exercise suppressed the expression of immediate-early genes in the prefrontal cortex of the aged rats. Conclusion This study suggests that long-term exercise represses early response genes, and in this way, it increases resistance to stress, diminishes anxiety-related behavior, and improves social behavior. These findings underscore the need to consider appropriate time to start exercise to prevent stress induced anxiety related behavior.
Second-harmonic generation and fluorescence lifetime imaging microscopy through a rodent mammary imaging window

Tumor-Associated Collagen Signatures (TACS) have been identified that manifest in specific ways during breast tumor progression and that correspond to patient outcome. There are also compelling metabolic changes associated with carcinoma invasion and progression. We have characterized the difference in the autofluorescent properties of metabolic co-factors, NADH and FAD, between normal and carcinoma breast cell lines. Also, we have shown in vitro that increased collagen density alters metabolic genes which are associated with glycolysis and leads to a more invasive phenotype. Establishing the relationship between collagen density, cellular metabolism, and metastasis in physiologically relevant cancer models is crucial for developing cancer therapies. To study cellular metabolism with respect to collagen density in vivo, we use multiphoton fluorescence excitation microscopy (MPM) in conjunction with a rodent mammary imaging window implanted in defined mouse cancer models. These models are ideal for the study of collagen changes in vivo, allowing determination of corresponding metabolic changes in breast cancer invasion and progression. To measure cellular metabolism, we collect fluorescence lifetime (FLIM) signatures of NADH and FAD, which are known to change based on the microenvironment of the cells. Additionally, MPM systems are capable of collecting second harmonic generation (SHG) signals which are a nonlinear optical property of collagen. Therefore, MPM, SHG, and FLIM are powerful tools with great potential for characterizing key features of breast carcinoma in vivo. Below we present the current efforts of our collaborative group to develop intravital approaches based on these imaging techniques to look at defined mouse mammary models.
Charge collection scanning electron microscopy

This review encompasses the application of the scanning electron microscope to the study and characterization of semiconductor materials and devices by the Electron Beam Induced Conductivity (EBIC) method. In this technique, the charge carriers generated by the electron beam of the microscope are collected by an electric field within the material and sensed as a current in an external circuit. When employed as the video signal of the SEM, this collected current image reveals inhomogeneities in the electrical properties of the material. The technique has been used to determine carrier lifetime, diffusion length, defect energy levels, and surface recombination velocities. Charge collection images reveal the location of p‐n junctions, recombination sites such as dislocations and precipitates, and the presence of doping level inhomogeneities. Both the theoretical foundation and the practical aspects of these effects are discussed in a tutorial fashion in this review.
Interlayer exchange coupled composite free layer for CoFeB/MgO based perpendicular magnetic tunnel junctions

We have investigated the effect of Ta insertion thickness on perpendicular magnetic anisotropy (PMA) in [Co/Pt multi-layers]/Ta/CoFeB (Hard/Soft) composite free layer. For insertions less than 0.6 nm thick, the ferromagnetic exchange was strong enough to switch the two layers together. The exchange turned from ferromagnetic to anti-ferromagnetic in nature for Ta insertion thickness above 0.7 nm. We observed increase in PMA with increasing Ta insertion thickness. It was noticed that this increase in PMA was caused by the enhancement of CoFeB/MgO interface anisotropy. The interface anisotropy increased by more than 0.9 erg/cm2 as the Ta insertion thickness increased from 0 nm to 0.5 nm. The Hk value for the composite free layer with 0.5 nm thick Ta insertion is around 11 kOe leading to a high thermal stability factor, estimated around 152 for 20 nm nano-dots.
Dynamic modelling and causality

Abstract In 1965 Erling Sverdrup published a paper on the use of Markov chains in modelling disability. This paper has been a source of inspiration for further development of statistical theory for Markov processes and the closely related counting processes. The main importance of introducing Markov chains does not lie so much in the Markov property, but more in the fact that a dynamic stochastic process is used as model. For statistical purposes one may dispense with the Markov assumption and may use much more general dynamic models than the Markovian ones. The key concept in this extension is the Doob-Meyer decomposition which is a part of modern martingale theory. With this as a starting point I define a general dynamic statistical model and discuss several examples. Intuitively, a dynamic model will be one where the future development is “explained” in terms of the past. Not surprisingly this is closely related to a causal understanding of the phenomenon. Tore Schweder in 1970 wrote a paper where he r.
An X‐Ray Study of Carbon Black

X‐ray studies have been made of a number of carbon blacks, prepared under different conditions, and subject to various heat treatments. The patterns were made in evacuated cameras, using Cu Kα radiation monochromated by reflection from rocksalt. The patterns consist of crystalline reflections (00l), and two‐dimensional lattice reflections (hk). The structure is one of true graphite layers arranged roughly parallel and equidistant, but otherwise completely random. The dimensions within a layer are the same as in graphite; the layer separation is somewhat larger than in graphite. The effect of heat treatment is to increase the size of the parallel layer groups. At graphitization the material changes discontinuously to the crystalline graphite structure. The usual carbon black is not finely divided graphite. Small angle scattering studies indicate the existence of clusters a few hundred angstroms in size. It is these clusters which are measured by microscope counts, by the electron microscope, and by surface.
Polygonal Mesh Partitioning for NURBS Surface Generation

Surface reconstruction and NURBS surface generation based on 3D surface mesh partitioning are more essential today. In this paper, we present a new method of automatic partitioning complex surface meshes into the bounded regions with four corner points (quadrilateral regions) based on using control points (notches) for NURBS surface generation. The procedure of this method consists of 4 major steps: (1) the 3D polygons mapping into 2D polygons; (2) convex decomposition of the polygons in the 2D space; (3) subdivision of each polygons into quadrilateral regions; (4) mapping the received 2D regions onto the 3D original surface mesh. Main contribution in this paper is automatic partitioning of the 3D segmented parts of complex surfaces into quadrilateral regions based on combination of segmentation, mapping, and subdivision techniques. Automatic partitioning allows us to create not rectangular but quadrilateral regions without using any user-dependent parameters for further NURBS surface generation.
Analysis of oral changes in hospitalized patients with Covid-19: a retrospective cohort study

The outbreak of a new coronavirus was identified in Wuhan, China in late 2019. SARS-CoV-2, spreads through salivary droplets from a carrier causing a respiratory illness. Its clinical behavior is variable and manifests itself with mild symptoms, moderate or developing a severe respiratory infection. The oral cavity was identified as a gateway for the virus and evaluating its possible role as an aggravating factor in the infectivity and progression of the infection was the objective of this study. A retrospective cohort study was performed with data from 274 medical records of patients with COVID-19. They were collected at the patient's admission, with seven and fourteen days to analyze the occurrence of oral alterations and relate them to the severity of the infection. In total, 154 patients had oral alterations. The most frequent oral alteration was the presence of ulcerations in the mucosa at the three collection times (T0, T1 and T2). Complementary tests were red blood cells, platelets, leukocytes, bleeding time, TGP, TGO, albumin, creatinine, CRP, urea, d-dimer and leukocyte-lymphocyte ratio. No predictors were observed for the development of oral changes in patients with COVID 19. Changes in the oral mucosa were observed in most of the patients analyzed. An association between diabetic patients and the presence of oral lesions was observed in the evaluated patients, after 7 and 14 days. The study revealed that patients with changes in the oral mucosa had a more severe evolution of COVID-19, including death, indicating that the presence of oral changes may be related to an unfavorable prognosis of the infection.