Miracle-dz/UniFAR-FTUs huggingface dataset:
Long-term mitral valve repair outcomes and hospital volume: 15 years’ analysis of an administrative dataset

Background Procedural volume has been documented as an important contributor to operative outcomes for most complex surgical procedures. Mitral valve repair (MVRep) has been associated with excellent results, and it is increasingly adopted in many cardiac surgical centers. We sought to investigate if procedural volume is associated with better clinical long-term outcomes after MVRep. Methods We analyzed the 10-year outcomes after MVRep by procedural volume for each cardiac surgery center in an Italian Region, Lazio, during the last 15 years, using a regional administrative dataset. Results Between 2006 and 2020, 4961 patients were treated in seven cardiac surgery centers for an isolated mitral valve surgery (2677 underwent MVRep). At multivariate analysis, mitral valve replacement (MVR) (vs. MVRep) resulted one of the independent predictors of 30-day mortality [adjusted odds ratio (OR) 3.40; 95% confidence interval (CI) 1.96–5.90; P < 0.0001]. Notably, a clear association between hospital volume of mitral valve surgery (>40 per year) and high rate of MVRep (>50%) was found. At 10 years, the incidence of mortality and the rate of death and rehospitalization for heart failure after MVRep were significantly lower in high-volume vs. low-volume hospitals. Conclusion Our data suggest that hospital volume is associated with a high rate of MVRep and long-term benefits in terms of mortality and recurrence of heart failure.
Airway management: Shining a New Light

Airway management is practiced by anaesthesiologists, emergency physicians, critical care experts, and less frequently by specialists in other disciplines. Pre hospital personnel and military medics are also called upon to provide airway support for acutely ill and injured patients. Intubation success rates are decreased in the pre hospital setting, and when a difficult airway is unexpectedly encountered [1]. Novel approaches to improved airway rescue and management include the use of video-enable devices, which can mitigate many unfavorable factors which contribute to low intubation success rates in emergency situations. Laryngeal visualisation is a primary determinant of successful intubation, and video-enabled devices significantly improve visualisation of laryngeal structures [2]. Training in the utilisation of video-enabled devices requires deliberate practice for unique eye-hand coordination and psychomotor skill development. Fundamental skill acquisition and device orientation can be accomplished utilising manikin airway simulators in both normal and difficult airway configurations.
D/H kinetic isotope effect in the reaction CH4+Cl

The D/H kinetic isotope effect (KIEClD) in the reaction of CH4 with Cl has been investigated using a tunable diode laser absorption spectrometer (TDLAS) to measure 12CH3D/12CH4 ratios. A KIEClD of 1.508±0.041 was obtained at room temperature (296 K). Experiments employing Fourier transform infrared measurements of 12CH3D/12CH4 ratios confirmed this result. An investigation of the temperature dependence showed an increase of KIEClD (1.592±0.057 at 223 K) with decreasing temperature. This very large D/H fractionation effect affects the overall isotope fractionation in the middle and upper stratosphere, where Cl contributes substantially to the total removal of CH4.
Monocyte populations are involved in the pathogenesis of experimental epidermolysis bullosa acquisita

Monocytes play a significant role in the pathogenesis of most inflammatory diseases, including autoimmune diseases. Herein, different subpopulations of monocytes often play differential, partially antagonistic roles, in the regulation of tissue populations. Pemphigoid diseases constitute a group of autoimmune blistering skin diseases featuring a marked infiltration of the dermis with immune cells, including monocytes. The monocyte subsets infiltrating the skin, however, have largely remained elusive. Monocyte adhesion and recruitment into the inflamed tissues are regulated by chemokine receptors, most prominently by CCR2 and CX3CR1. To delineate the involvement of monocyte populations in autoimmune blistering skin diseases, we spatiotemporally monitored the dynamic spectrum of monocyte populations that infiltrate the inflamed skin using multiphoton intravital imaging and reporter mice for chemokine receptors. Experimental epidermolysis bullosa acquisita (EBA) was induced by injection of anti-murine type VII collagen (amCOLVII) IgG into the Csf1rEGFP-reporter mice, where circulating myeloid cells, such as monocytes and neutrophils, express an EGFP. EGFP+ cells, including neutrophils and monocytes, were present in the skin, immediately after the deposition of the amCOLVII antibody at the dermal-epidermal junction. To investigate the recruitment and involvement of different monocyte-derived cell populations in the disease course further, EBA was induced in CCR2RFP/+-reporter and CX3CR1GFP/+-reporter mice. A comparable distribution of red fluorescent protein (RFP)+ or green fluorescent protein (GFP)+ was found in both diseased mice and their respective controls over time, indicating the similar recruitment of monocytes into the skin following the binding of autoantibodies. Experiments were extended to the CCR2RFP/RFP-deficient and CX3CR1GFP/GFP-deficient mice to determine whether monocyte recruitment and disease severity are compromised in the absence of the receptor. A comparable pattern was seen in the recruitment of monocytes into the skin in both reporter and deficient mice. However, in contrast to similar disease severity between CX3CR1-deficient and reporter mice, CCR2-deficient mice developed significantly less disease than CCR2-reporter mice, as indicated by the percentage of affected area of ears. Collectively, our observations indicate that while CCR2 and CX3CR1 receptors are not involved in the recruitment of monocytes into the skin, CCR2 deficiency is associated with improved disease outcomes in experimental EBA in mice.
Do Solar Activities Cause Local Earthquakes? (New Zealand)

The relationships between solar activities (sunspots, solar 10.7cm radio flux, solar irradiance, and solar proton events) and local earthquakes investigated in this paper. The geographical location of study is New Zealand area. All earthquakes data have been chosen for , from first of 1970 to Jun 2012. The study reveals the following conclusions: 1) The total numbers of earthquakes strongly show annually an increasing in number of earthquakes in New Zealand from 42 years ago. 2) The maximum earthquakes occur frequently around the minimum years of solar activities, 3) The maximum earthquakes occurs in minimum years of sunspots number with a good correlation coefficient. 4) The maximum earthquakes occur in the minimum solar cm radio flux with strong correlation coefficient.
CRV: Automated Cyber-Resiliency Reasoning for System Design Models

We present the design and implementation of an automated static analysis approach and corresponding diagnostic tool, called Cyber Resiliency Verifier (CRV), to check whether a system design satisfies its end-to-end guarantees when the integrity of one or more of its components cannot be guaranteed. CRV’s key insight is to reason about effects of integrity attacks instead of concrete attacks, enabling it to reason also about the impact of future attacks having the same captured effects. We demonstrate CRV’s effectiveness with a case study on a realistic design of an unmanned aerial delivery drone.
Chronisch-entzündliche Darmerkrankungen bei Kindern und Jugendlichen

Ergebnisse: Bei Kindern und Jugendlichen mit CED kommt es häufig zu einem ausgedehnten Befall und einem aggressiven Verlauf. Dennoch sind nur Infliximab und Adalimumab als Biologika für diese Patientengruppe zugelassen. Bei Morbus Crohn ist die exklusive enterale Ernährungstherapie die erste Wahl zur Remissionsinduktion. Bei (peri-)analer Fistelbildung erfolgt die Therapie primär mit Infliximab. Kortikosteroide und Aminosalizylate werden bei Morbus Crohn zurückhaltend eingesetzt. Kinder und Jugendliche mit Colitis ulcerosa werden zur Remissionsinduktion mit Aminosalizylaten oder Prednisolon behandelt. In der Regel ist eine mehrjährige medikamentöse Erhaltungstherapie mit Thiopurinen bei Morbus Crohn und schwerer Colitis ulcerosa oder Aminosalizylaten bei leichter bis mittelschwerer Colitis ulcerosa bis mindestens zum Abschluss der Pubertät indiziert. Bei therapierefraktären Verläufen werden Methylprednisolon, TNF-α-Antikörper und/oder Calcineurin-Inhibitoren eingesetzt. Chirurgische Interventionen folgen demselben Indikationsspektrum wie bei Erwachsenen. Besondere Bedeutung kommt den unerwünschten Arzneimittelwirkungen, den Bereichen Ernährung, Wachstum und Entwicklung sowie dem strukturierten Übergang in die Erwachsenenmedizin zu.
Dip-moveout by Fourier transform

The conventional normal‐moveout (NMO) and common‐midpoint (CMP) stacking process enhances reflections having a particular moveout velocity, while attenuating events (such as multiple reflections) having different moveout velocities. Unfortunately, this process also acts as a dip filter applied to the CMP stack. In other words, NMO and stacking enhances reflections having a particular slope in the CMP stack, while attenuating reflections having different slopes. NMO and stacking, like any dip filter, degrades lateral resolution. Fortunately, this dip‐filtering action can be suppressed by applying, in addition to NMO, a prestack process known variously as DEVILISH, prestack partial migration, and dip‐moveout. As the latter term implies, this process is a dip‐dependent moveout correction that enables reflections from both horizontal and dipping reflectors to be stacked with the same NMO velocity. Stated another way, NMO velocities estimated from dip‐moveout‐corrected seismograms are independent of the dips o.
Field Investigations and Experimental Modelling of the Tsunami-induced Extreme Hydrodynamic Forces on Structures

A comprehensive research program on tsunami-induced forces on infrastructure located in coastal areas was initiated at the Department of Civil Engineering of the University of Ottawa, Canada, in collaboration with the Canadian Hydraulics Centre, National Research Council of Canada. The paper is presenting some of the results of this interdisciplinary project undertaken by coastal and structural engineers. This research project spanned over a period of six years and included posttsunami field reconnaissance missions as well as physical and numerical modelling of the tsunamiinduced hydrodynamic forces on buildings and their component structural elements. The authors have conducted several field investigation following the 2004 Indian Ocean Tsunami (Thailand, Indonesia, Sri Lanka, and Tanzania) and, more recently, following the February 2010 Chilean Tsunami. One of the goals of this research project is to contribute to the understanding of the complex hydrodynamic mechanisms of impact and extreme loading on nearshore buildings located in tsunami-prone areas. At the same time, this project attempts to improve the quantitative estimation of these hydrodynamic loads and to further propose new formulations for the design of inland structures located in areas which affected by potential tsunami wave attack. The paper presents some brief information on the post-tsunami reconnaissance missions, and in more detail, partial results of the experimental program.
Mitigating Climate Change with Forest Climate Tools

This paper develops the FRICE, a framework that determines optimal levels of forest climate tools in the context of global climate policy. The paper integrates afforestation and avoided deforestation into the well-known global multi-regional integrated assessment model, RICE-2010. The paper finds that climate forest tools can play an essential role in global climate policy and that this role is increasingly important under stringent temperature targets. Under a 2C temperature target, the model reveals that emission reductions from avoided deforestation are quickly exhausted whereas afforestation is capable of substantially reducing emission reductions in both the medium and long run. The model also indicates that the most significant reductions in emissions from avoided deforestation and afforestation can be achieved by focusing policy efforts on tropical forests.
Quality assessment of drinking water in Temeke District (part II): Characterization of chemical parameters

This paper presents a study on drinking water quality in Temeke District (Dar es Salaam), which involved analyses of chemical parameters of drinking water samples from different drinking water sources. The drinking water sources examined included tap water, river water and well water (deep and shallow wells). Water quality studied includes pH, chloride, nitrate and total hardness levels. The concentrations of total hardness in mg CaCO 3 /L and chloride were obtained by titration method while the nitrate concentration levels were determined by spectrophotometer. Tap water was found to be of high quality than other sources in terms of chemical characteristics. The study revealed that the chemical parameters of water sources did not meet the permissible World Health Organization (WHO) and Tanzania Bureau of Standards (TBS) levels. Examining exceedence above the WHO standards, it was revealed that most of the samples contained chloride levels above allowable WHO limits. It was recommended that drinking water sources for domestic use should be protected from pollution sources. Key words: Drinking water quality, pH, chloride, nitrates, total hardness, exceedence.
CARDIFF METROPOLITAN UNIVERSITY Prifysgol Fetropolitan Caerdydd CARDIFF SCHOOL OF SPORT DEGREE OF BACHELOR OF SCIENCE (HONOURS) SPORT CONDITIONING, REHABILITATION AND MASSAGE 2013-4 THE RELATIONSHIP BETWEEN STRENGTH, POWER AND CHANGE OF DIRECTION SPEED IN FEMALE GAMES-BASED ATHLETES Dissertation sub

Discussion and Conclusions 2 To include: collation of information and ideas and evaluation of those ideas relative to the extant literature/concept/theory and research question/problem; adoption of a personal position on the study by linking and combining different elements of the data reported; discussion of the real-life impact of your research findings for coaches and/or practitioners (i.e. practical implications); discussion of the limitations and a critical reflection of the approach/process adopted; and indication of potential improvements and future developments building on the study; and a conclusion which summarises the relationship between the research question and the major findings.
Synthesis and Characterization of Polyester Derived from Glycerol and Its Application as an Adhesive on Different Adherents

With the increase in the supply of glycerol and its economic devaluation, it is important to develop strategies that add value to this substance. Among the various alternatives, one application is its use as a precursor in the synthesis of new polyesters. Therefore, this work describes the condensation reaction of glycerol with valeric acid, obtaining functionalized glycerol, which was used in the polycondensation reaction with terephthalic acid. The samples were characterized by infrared spectroscopy, thermogravimetric analysis, hydrogen nuclear magnetic resonance and differential scanning calorimetry. Spectroscopic analyses confirmed the conversion of the reagents into esters and polyesters. The polyesters showed superior thermal stability than the individual components, a glass transition temperature of -3.8 °C and adhesive properties on glass, wood, paper and rigid polyvinyl chloride substrates. The adhesive capabilities of the samples were compared with those of commercial adhesives already established in the Brazilian market. Samples of polyesters synthesized through the reaction between functionalized glycerol and terephthalic acid showed adhesive behavior in the range of mechanical resistance observed in commercial adhesives, with an elastic modulus ranging from 60.9 ± 36.0 MPa to 162.1 ± 102.4 kPa, depending on the type of adhesive substrate, behaving either as an elastic and/or thermoplastic adhesive.
VLF observation of long ionospheric recovery events

We introduce a new class of Early/fast VLF events with recoveries of up to 20 min, much longer than typical Early/fast and Lightning‐induced Electron Precipitation (LEP) events which recover to pre‐event levels in ≲200 s. Three distinct types of long recovery events are observed, each exhibiting different characteristics, with the observed features of at least some of the event types consistent with the possibility of persistent ionization at altitudes below 60 km as put forth by Lehtinen and Inan (2007).
Population structure and genetic diversity of Streptococcus suis isolates obtained from the United States

Diseases caused by the zoonotic pathogen Streptococcus suis are an extensive economic problem as well as an animal welfare concern for the global swine industry. Previous studies have evaluated the genomic diversity and population structure of S. suis isolates, however, the majority of these studies utilized isolates obtained from countries other than the U.S. This study applied whole genome sequencing and cgMLST-based typing to evaluate the population structure and genetic relatedness among S. suis isolates obtained within the U.S. The established high-resolution phylogenomic framework revealed extensive genomic variation and diversity among the sampled S. suis isolates, with isolates from the U.S. and from countries outside the U.S. found interspersed in the phylogeny. S. suis isolates obtained within the U.S. did not cluster by state or geographic location, however, isolates with similar serotypes, both obtained from within and outside the U.S., generally clustered together. Average nucleotide identity (ANI) values determined for the S. suis genomes were extensively broad, approaching the recommended species demarcation value, and correlated with the phylogenetic group distribution of the cgMLST-based tree. Numerous antimicrobial resistance (AMR) elements were identified among both U.S. and non-U.S. isolates with ble, tetO, and ermB genes identified as the most prevalent. The epf, mrp, and sly genes, historically used as markers for virulence potential, were also observed in the genomes of isolates that grouped together forming a subclade of clonal complex 1 (CC1) isolates. Collectively, the data in this report provides critical information needed to address potential biosurveillance needs and insights into the genetic diversity and population structure of S. suis isolates obtained within the U.S.
Long-Term Research on Biodiversity in West Khentey, Northern Mongolia

Biodiversity is studied at ecosystem, community, and species level around Khonin Nuga, where the University Goettingen supports a research station since 15 years (established 1997 in cooperation with the National University of Mongolia). In that period 39 scientists have been involved and 67 students graduated with theses (7 PhD) about field work at that station. Inventories started at 1998 for several taxa and are now compiled in a book, which will be printed 2012 in Ulaanbaatar. It covers fungi, lichens, plants, several insect groups, spiders, crustaceans, and all vertebrate classes. For all taxa adequate experts proved the species lists. Because of both the high species richness in most taxa and the new threat by logging and frequent anthropogenic fires the area around Khonin Nuga has to be denoted a “hotspot of biodiversity” for Mongolia. The long-term ecological research led to an understanding of the dynamics of the different forest types: the old-growth forest with dominating Pinus sibirica shows a gap-dynamics in regeneration, whereas the Larix sibirica – Betula platyphylla forests are driven by frequent fire disturbances. The anthropogenic fires are destructive for the biodiversity in forests. The tree species Betula platyphylla proved as a key resource for many saproxylic organisms and hole-breeding birds. The southfacing slopes are covered naturally by dry-mountain-steppes where trees are beyond their limits. In the river valleys meadows can form stable communities even though the floodplains allow tree growth physiologically. At the community level we studied for more than 10 years the dynamics of small mammal populations. At the southern edge of the taiga there is no pattern of cycles. The dynamics (fluctuation with population crash) is mainly caused by adverse winter conditions, but the dynamics can also shift to intrinsic factors at high population densities and favorable winter weather. At the species level we studied the reproduction strategy of a social corvid, the Azurewinged magpie (Cyanopica cyana). In years with favorable conditions it breeds without helpers. In years with high nest predation we observed 10 % helpers, but in a year with a colony disaster by burning 64 % helpers improved significantly the breeding success. The southern boreal forest is an area of special interest for conservation, containing the most diverse assemblages of species within the boreal forest. Intact, contiguous boreal forest will be best able to keep up with rapidly changing climate conditions because of high connectivity, providing diverse habitats for wildlife by its heterogeneity, high potential for regeneration, maintaining the soil system, and moderating local climate. Contributions to the long-term studies came from Dulamsuren Ch., Oyunsanaa B. , Gottschalk E. , Sheftel B. , Gantulga B. and others found in the references.
Objectivizing Measures of Post-Stroke Hand Rehabilitation through Multi-Disciplinary Scales

There is a wide variety of tools and measures for rehabilitation outcomes in post-stroke patients with impairments in the upper limb and hand, such as paralysis, paresis, flaccidity, and spasticity. However, there is a lack of general recommendations for selecting the most appropriate scales, tests, and instruments to objectively evaluate therapy outcomes. Reviews on upper limb and hand measurements reveal that clinicians’ choices of tools and methods are highly varied. Some clinicians and medical teams continue to employ non-standard and unverified metrics in their research and measurements. This review article aims to identify the key parameters, assessed by outcome measures and instruments, that play a crucial role in upper limb and hand rehabilitation for post-stroke patients, specifically focusing on the recovery of hand function. The review seeks to assist researchers and medical teams in selecting appropriate outcome measures when evaluating post-stroke patients. We analyze the measured factors and skills found in these outcome measures and highlight useful tools that diversify assessments and enhance result objectivity through graphical representation. The paper also describes trends and new possibilities in hand outcome measures. Clinicians frequently use proven devices, such as EMG, goniometers, and hand dynamometers. Still, there is a growing trend towards incorporating technologies, such as pose and position estimation, using artificial intelligence, or custom hand grip measurement devices. Researchers are increasingly adopting scales previously successful in orthopedic and surgical patients, recognizing their potential for objectivizing outcomes in neurological patients with post-stroke hand complications. The review included only adults over the age of 18. Outcome measures were tested for usefulness in the rehabilitation of stroke patients.