Miracle-dz/UniFAR-FTUs huggingface dataset:
Chitosan-Reinforced Gelatin Microspheres-Modified Glass Ionomer Cement (GIC): A Novel Bone Alloplast Graft Material Synthesis and an In Vivo Analysis

Aim and objective The study aimed to assess and evaluate the efficacy of glass ionomer modified with chitosan-reinforced gelatin microspheres on bone formation. Materials and methods The study involved three groups: Group I comprised plain glass ionomer cement; Group II comprised glass ionomer cement/gelatin (70:30 wt%); in Group III, glass ionomer cement/gelatin/chitosan (70:30%) scaffold were made into discs; the gelatin microspheres were synthesized by oil emulsion method. The synthesized scaffold was subjected to the following in vitro testing, Instron Universal Testing Machine (UTM), U3000, (Instron Corporation, Norwood, Massachusetts, United States) to assess compressive strength, scanning electron microscope (SEM) examination, and biocompatibility testing using hemocompatibility assay. The material was then tested in vivo; male Wistar albino rats, a total of nine animals, were utilized for this purpose. Three animals were used in each group; a femoral defect model was the model of choice for the experiment and the animals were observed for a period of four weeks, following which the animals were sacrificed and sent for histopathological analysis. Results The compression testing was carried out using UTM; test group I was 33 MPa, test group II was 2.3 MPa, and test group III was 25.75 MPa. SEM (JSM-IT800 Schottky Field Emission NANO SEM (JEOL, Tokyo, Japan)) analysis was done to observe the porosity of the fabricated scaffold with the average measurement of 0.12 ± 0.2 μm in test group II and 0.29 ± 0.4 μm in test group III. Hemocompatibility reports noted 0.4-0.8% lysis for the synthesized scaffolds. Histopathology staining of the femur defects showed that group III favoured bone formation. One-way analysis of variance (ANOVA) and post hoc Bonferroni test was done on the data. The optical density values of the alizarin red stained slide showed statistical significance for group III. Conclusion In conclusion, the synthesized scaffolds are biocompatible, distribution of porosity and pore characteristics in the glass ionomer cement/gelatin/chitosan group is better than that of the glass ionomer cement/gelatin group. The glass ionomer cement/gelatin/chitosan group had better compressive strength and induced more bone formation compared to the other test group and the control. Thus, the novel glass ionomer modified with chitosan-reinforced gelatin microspheres has optimal properties to be used as a bone graft material.
Paleoliquefaction Features at Archaeological Sites in Japan

Liquefaction features from paleoearthquakes are common at archaeological sites of Japan. The most remarkable features are dykes of sand and gravel in which the clasts become finer approaching the surface. Liquefaction at some sites occurred not only in sand but also in gravel. Some archaeological features have been entrained and moved in sand intrusions.
Serie guías clínicas: Manejo de feto muerto in utero

1. Conocer las principales etiologías causantes de muerte fetal. 2. Proponer una estrategia diagnóstica en la muerte fetal. 3. Identificar los factores de riesgo modificables en la prevención de muerte fetal. 4. Proponer un estudio etiopatogénico post parto del feto muerto in utero (MFIU). 5. Ante el antecedente de MFIU proponer estrategias de prevención de este accidente. 6. Proponer el manejo clínico del binomio madre hijo en MFIU.
Teachers' Perceptions on Instructional Leadership: Drawing Implications for Professional Development Program for Instructional Leaders

Instructional leadership is an essential component of any educational institution. The skills and competencies of instructional leaders are very important to deliver quality education and school improvement. The main purpose of this study was to examine the teachers’ perceptions on instructional leadership in a private school in basic education in the Philippines. The Instructional Leadership Questionnaire by Al-Omari was adapted to determine the perceptions of faculty on effective use of resources, communication skills, serving as instructional resource, and being visible and accessible. A total of 104 respondents voluntarily participated. Results show that respondents have positive perception on all four components of instructional leadership which can be surmised that instructional leaders should be able to demonstrate skills and competencies on effective use of resources, clear communication, serve as instructional resource, and being visible and accessible. Further research is recommended to determine the effect of these components to the actual teaching and learning implementation in the school.
L'autosurveillance des systèmes de collecte : Métrologie en réseaux d'assainissement

L'autosurveillance des systemes de collecte a ete intstituee pour repondre a l'esprit de la directive europeenne sur le traitement des eaux residuaires urbaines du 21 mai 1991. Celle-ci fixe d'une part les modalites de controle des performances des stations d'epuration et precise par ailleurs que les rejets d'un systeme d'assainissement doivent etre consideres d'une maniere globale. Il est donc logique d'instituer un suivi des rejets effectes a l'amont des stations d'epuration. Les textes de reference en droit francais sont la loi sur l'eau du 3 janvier 1992 et l'arrete du 22 decembre 1994 relatif a la surveillance des ouvrages de traitement et de collecte. Apres une presentation des principales dispositions de ces textes et des procedures utilisables pour leur mise en application, un bilan de la situation actuelle est presente.
Sensorless Adaptive Nonlinear Damping Backstepping Controller for Doubly-Fed Induction Machine in Wind Power Generation

This paper deals with the design of an adaptive controller for Doubly-Fed Induction Generator (DFIG) connected to a stable electrical grid and works in wind generation. The proposed algorithm combines the backstepping technique and a nonlinear damping tool. The aerodynamic torque is supposed to be unknown and will be estimated in real time. In addition, rotor currents of the generator are assumed not to be available for measurements and will be constituted using an observer. This controller achieves the maximum power point tracking (MPPT) and permits to control the reactive power delivered to the grid. The mathematical development of the model and the control design are discussed in detail. The overall stability of the system is shown using Lyapunov theory. Matlab and Simulink based simulation results show the superiority of the proposed controller compared to the conventional controller without adaptation.
Activable Photodynamic DNA Probe with an “AND” Logic Gate for Precision Skin Cancer Therapy

Photodynamic therapy (PDT) has emerged as a promising approach for squamous cell carcinoma treatment but hindered by tumor hypoxia, acquired resistance, phototoxicity, and so on. To address these issues, we developed a smart strategy utilizing activable photosensitizers delivered by an aptamer-functionalized DNA probe (ADP). The ADP incorporated an AS1411 aptamer for tumor targeting and a linear antisense oligonucleotide (ASO) for recognition of Survivin mRNA. In the absence of the target, PDT remained quenched, thereby avoiding phototoxicity during circulation and nonselective distribution. With the aid of the aptamer, ADP achieved selective targeting of tumors. Upon internalization, ADP targeted recognized Survivin mRNA, triggering PDT activation, and releasing ASO to down-regulate Survivin expression and reverse tumor resistance. Consequently, the activable photosensitizers exhibited an “AND” logic gate, combining tumor-targeting delivery and tumor-related gene activation, thus enhancing its specificity. Additionally, the incorporation of hemin into the ADP provided catalase activity, converting tumor-abundant H2O2 into O2, thereby ameliorating tumor hypoxia. The resulting functionalized G-quadruplex/hemin–DNA probe complex demonstrated targeted delivery and activation, minimized side effects, and enhanced PDT efficacy in both xenograft tumor-bearing mice and patient-derived xenograft models. This study offers a unique and promising platform for efficient and safe PDT, thus holding great potential for future clinical translation and improved cancer therapy.
Association between serum total bilirubin and diabetic kidney disease in US diabetic patients

Background Bilirubin has been widely reported to be a protective factor against diabetic kidney disease (DKD) in Asian populations. However, few large-sample analyses have been conducted in American populations. This study aimed to investigate the association between serum total bilirubin (STB) level and DKD in a US diabetic cohort. Methods This cross-sectional study enrolled participants from the National Health and Nutrition Examination Survey (NHANES) 2003–2018. Univariate and multivariate logistic regression analyses were performed to assess the association between STB level and DKD. Three models were conducted to control the potential confounding factors. Subgroup analysis was carried out for further validation. Results Among the 5,355 participants, the median age [interquartile range (IQR)] was 62 [52–71] years; 2,836 (52.96%) were male, and 1,576 (29.43%) were diagnosed with DKD. In the entire cohort, no significant association between STB level and DKD was observed in any logistic regression models (p > 0.05). Subgroup analysis revealed that, in U.S. diabetic males, STB levels > 11.98 µmol/L were associated with a nearly 30% lower risk of DKD than STB levels ≤ 8.55 µmol/L. Additionally, a moderate STB level (8.56–11.98 μmol/L) was found associated with a nearly 25% lower risk of DKD in U.S. diabetic patients over 65 years old. Conclusion The association of STB level with DKD may depict differences across diverse populations, among which the impact of race, sex, and age requires thorough consideration and relevant inferences should be interpreted cautiously.
Delta Storage Pool Deficiency: A Pediatric Case Report and Review of the Literature

Platelet storage deficiencies are a heterogeneous group of bleeding disorders of variable severity caused by decreased number or content of platelet granules. We present the case of a 10-year-old patient with no personal history of previous bleeding who was admitted to the emergency department due to menorrhagia and mucocutaneous pallor. Common disorders of primary and secondary hemostasis were ruled out. Subsequently, a study of electron microscopy of platelets was performed, which reported the presence of alpha granules with a decreased number of dense granules. Currently, the patient receives treatment with tranexamic acid during menstrual periods, supplementation with ferrous sulfate, and oral contraceptives, achieving control of bleeding episodes.
Characterizing the Seafloor Sediment Layer Using Teleseismic Body Waves Recorded by Ocean Bottom Seismometers

This study presents an approach to better characterize the P‐wave and S‐wave velocity structure of the seafloor sediment layer using ocean bottom seismometers. The presence of low‐velocity seafloor sediment layers influences the observed seismic record at the seafloor over a broad frequency range, such that detailed knowledge of this sediment structure is essential to predict its effect on teleseismic records. We use the radial component of teleseismic P waves and autocorrelation functions of the radial, vertical, and pressure components of teleseismic P and S waves to obtain sediment layer models using the Markov chain Monte Carlo approach with parallel tempering. Synthetic tests show that the body waves constrain the P‐ and S‐wave impedances and travel times and the P‐ to S‐wave velocity ratio of the sediment layers. The proposed method resolves thin layers at a high resolution, including the uppermost thin (∼50 m to a few hundred meters) low S‐wave velocity layer. Real data applications at sites across the Pacific Ocean that are coincident with previous in situ studies demonstrate the effectiveness of this method in characterizing the seafloor sediment unit. The sediment models characterized by this new approach will allow us to more accurately predict and correct the effects of sediment layers in generating P‐ and S‐wave reverberations.
The Impact of Knowledge About the Environment on The Attitudes and Behavior of Young Consumers in The Food Market

This study examines the impact of environmental knowledge on the attitudes and behaviors of young consumers in the food market. This study found that consumers are increasingly recognizing the importance of green products and manufacturers are responding by incorporating green aspects into their marketing strategies. This study also found that there is a positive correlation between environmental knowledge and consumer attitudes and behaviors. This study used quantitative methods and analysed the data using regression analysis. The result show that both consumer attitudes and behaviors have a significant impact on environmental knowledge.
THE INFLUENCE OF LEADERSHIP, TRAINING AND WORK DISCIPLINE WITH WORK MOTIVATION AS AN INTERVENING VARIABLE ON THE PERFORMANCE OF EMPLOYEES OF THE PEKANBARU CITY BRANCH OF BPJS EMPLOYEES

This research was carried out at the BPJS Employment Pekanbaru City Branch Office, over a period of five months from April 2023 to August 2023.The population in this study were employees who worked at the BPJS Employment Office, Pekanbaru City Branch, totaling 124 respondents regardless of strata and specific areas of work.This research uses path analysis to test relationship patterns that reveal the influence of a variable or set of variables on other variables, both direct and indirect influences. So hypothesis one states that the influence of leadership on work motivation is significant. Hypothesis two states that the influence of Leadership on the Performance variable is significant. The third hypothesis states that the influence of training on work motivation is significant. The fourth hypothesis states that the influence of training on performance is significant. The fifth hypothesis states that the influence of Work Discipline on Work Motivation is significant. The sixth hypothesis states that the influence of Work Discipline on the Performance variable is significant. The seventh hypothesis states that the influence of work motivation on performance is significant. The eighth hypothesis states the direct influence of Leadership on Performance, thus it can be stated that Work Motivation can mediate the influence of Leadership on Performance. The ninth hypothesis states the direct influence of training on performance, thus it can be stated that work motivation can mediate the influence of training on performance. The tenth hypothesis states the direct influence of Work Discipline on Performance, thus it can be stated that Work Motivation can mediate the influence of Work Discipline on Performance.
Old school, new rules: floral meristem development revealed by 3D gene expression atlases and high-resolution transcription factor–chromatin dynamics

The intricate morphology of the flower is primarily established within floral meristems in which floral organs will be defined and from where the developing flower will emerge. Floral meristem development involves multiscale-level regulation, including lineage and positional mechanisms for establishing cell-type identity, and transcriptional regulation mediated by changes in the chromatin environment. However, many key aspects of floral meristem development remain to be determined, such as: 1) the exact role of cellular location in connecting transcriptional inputs to morphological outcomes, and 2) the precise interactions between transcription factors and chromatin regulators underlying the transcriptional networks that regulate the transition from cell proliferation to differentiation during floral meristem development. Here, we highlight recent studies addressing these points through newly developed spatial reconstruction techniques and high-resolution transcription factor–chromatin environment interactions in the model plant Arabidopsis thaliana. Specifically, we feature studies that reconstructed 3D gene expression atlases of the floral meristem. We also discuss how the precise timing of floral meristem specification, floral organ patterning, and floral meristem termination is determined through temporally defined epigenetic dynamics for fine-tuning of gene expression. These studies offer fresh insights into the well-established principles of floral meristem development and outline the potential for further advances in this field in an age of integrated, powerful, multiscale resolution approaches.
LITERATURE REvIEw: CANOPY HERBIVORY AND SOIL ECOLOGY THE Top- DOWN IMP ACT OF FOREST PROCESSES

Insects that feed on the foliage of trees can influence the quality of forest soils by dropping frass (feces) and leaf fragments to the floor. They can also modify the chemistry of rainwater that passes through the forest canopy. The effects of herbivore activity on forest soil processes are poorly understood. Potentially, insects may change soil fertility and the rates of decomposition of leaves that have fallen to the ground. This literature review examines our present understanding of these top-down impacts of forest canopy herbivory on soil processes.
Links Between Climate, Water And Waterborne Illness, And Projected Impacts Of Climate Change

______________________ 1 Foodborne, Waterborne, and Zoonotic Infections Division, Public Health Agency of Canada, 160 Research Lane, Ste 206, Guelph, ON N1G 5B2. Reach Dr Charron at Tel 01.519. 826.2173; Fax: 01.519. 826.2244, Email: Dominique_Charron@phac-aspc.gc. ca 2 Dept of Population Medicine, University of Guelph, Guelph, ON N1G 2W1. Reach Dr Waltner-Toews at Tel 01.519. 824.4120 X 54745; Fax: 01.519. 763.3117; Email:dwaltner@uoguelph.ca 3 Meteorological Service of Canada, Environment Canada, Toronto ON (Maarouf) and Ottawa ON (Yuzyk) 4 School of Engineering, University of Guelph 5 School of Rural Planning and Development, University of Guelph 6 Department of Mathematics and Statistics, University of Guelph 7 National Water Research Institute, Environment Canada, Gatineau, QC (Kent) and Burlington ON (Edge)
Image Guided Intensity Modulated Helical Radiation (Tomotherapy) Used as a Radiosurgical Tool

Introducción: Tomoterapia (HT) es un acelerador lineal sobre una Tomografía Computarizada (CT), es helicoidal por naturaleza e implica un CT de megavoltaje diario el cual es fusionado con el plan radioquirúrgico previo antes de entregar la dosis radioterapéutica (Radiocirugía Guiada por Imágenes). Esta tecnología es nueva a nivel mundial; hasta nuestro conocimiento, este es el primer reporte de radiocirugía intracraneal en Latinoamérica utilizando HT. Se describe la distribución de dosis en dianas pequeñas, así como también el flujo normal de un paciente y nuestra experiencia inicial.
A simulated robot versus a real robot: an exploration of how robot embodiment impacts people's empathic responses

In designing and evaluating human-robot interactions and interfaces, researchers often use simulated robots because of the high cost of physical robots and time required to program them. However, it is important to consider how interaction with a simulated robot differs from a real robot; that is, do simulated robots provide authentic interaction? We contribute to a growing body of work that explores this question and maps out simulated-versus-real differences, by explicitly investigating empathy: how people empathize with a physical or simulated robot when something bad happens to it. Empathy is particularly relevant to social human-robot interaction (HRI) and is integral to, e.g., companion and care robots. To explore our question, we develop a convincing HRI scenario that induces people’s empathy toward a robot, and explore psychology work for an empathy-measuring instrument. To formally evaluate our scenario and the empathy-measuring instrument in HRI scenario, we conduct a comparative user study: in one condition, participants have the scenario which induces empathy, and for the other condition, we remove any empathy inducing activities of the robot. With the validated scenario and empathy measuring Thesis Advisor Author James E. Young Stela H. Seo ii instrument, we conduct another user study to explore the difference between a real and a simulated robot in terms of people’s empathic response. Our results suggest that people empathize more with a physical robot than a simulated one, a finding that has important implications on the generalizability and applicability of simulated HRI work. As part of our exploration, we additionally present an original and reproducible HRI experimental design to induce empathy toward robots, and experimentally validated an empathy-measuring instrument from psychology for use with HRI. Thesis Advisor Author James E. Young Stela H. Seo
Vision-Based Topological Localization for MAVs

Vision-based topological localization is recently emerging as a promising alternative to metric pose estimation techniques in robotic navigation systems. Contrarily to the latter, which suffer from a quick degradation of their performance under non-ideal conditions (e.g., scenes with poor illumination and low amount of textures), topological localization trades off precise metric positioning with a more robust and higher-level location representation. State-of-the-art works in this direction, however, often neglect the spatiotemporal relationships between poses that are naturally induced by robotic navigation. Furthermore, these techniques are nearly unexplored for autonomous flying platforms. Inspired by these considerations, in this work, we propose a vision-based topological localization approach designed for Micro Aerial Vehicles (MAVs) applications. Our strategy exploits the framework of graph recurrent neural networks to model the spatial and temporal dependencies and estimate the location of the robot with respect to a topological graph representing the environment. We demonstrate with experiments on different sets of scenarios, including scenes that considerably differ from those used in the training phase, that our approach is able to outperform state-of-the-art place recognition baselines.