Miracle-dz/UniFAR-FTUs huggingface dataset:
Robust upper limb motion classification using Gaussian mixture models

− A Gaussian mixture model (GMM) based classification scheme is proposed in this paper to perform multiple limb motion discrimination using continuous myoelectric signals (MES) from limb muscles. The system is optimized with respect to the feature set, classifier and post-end processing of the decisions through comprehensive experimentation. The experiments examine the effects of various feature sets including the time-domain (TD) features and the autoregressive (AR) features with root mean square value (RMS), and the effect of the majority vote (MV) in post-processing on the classification performance. The averaged GMM classification performance is compared with that of three other motion techniques (a linear discriminant analysis (LDA), a linear perceptron (LP) neural network and a multilayer perceptron (MLP) neural network). The Gaussian mixture motion model achieves 96.91% classification accuracy using a combination of AR with RMS and TD (AR+RMS+TD) feature set for a six class problem. It has been demonstrated that this GMM-based limb motion classification scheme has superior classification accuracy and results in a robust method of motion classification.
L'interféromètre Virgo : propriétés optiques, stabilisation en fréquence du laser

Un interferometre a miroirs suspendus convertit les ondes gravitationnelles, perturbations de la geometrie de l'espace temps, en une variation de temps de vol d'aller-retour de photons entre deux masses inertielles au repos. J'ai realise l'asservissement en frequence du laser pour mesurer ces variations de temps de vol. La stabilite relative de frequence en boucle du laser est de 1e-21 sur 100 ms ; je montre que le systeme obtenu respecte les specifications. J'etudie dans le memoire les proprietes d'un systeme ou les boucles d'asservissements sont imbriquees. Les cavites optiques resonnantes de l'interferometre Virgo sont les elements essentiels de la conversion d'une onde gravitationnelle. J'etudie l'ensemble des proprietes d'un oscillateur Fabry-Perot. Je montre comment elles peuvent etre evaluees in situ a partir de mesures des fonctions de transfert utilisees pour leur verrouillage. Les cavites Fabry-Perot sont les oscillateurs de reference. Je fais un etat des lieux de l'ensemble des perturbations susceptibles de perturber la stabilite de phase.
Documents à structures multiples

RÉSUMÉ . Dans cet article, nous présentons les résultats de recherches collectives 1 sur la « multistructuralité » des documents, menées au sein de l’Institut des Sciences du Document Numérique (ISDN 2 ) et financées par la région Rhône-Alpes (Programmes Thématiques 2000-2003). Nos recherches ont abouti à la définition formelle et générique d’un document à structures multiples et d’un certain nombre d’opérations sur ce type de documents (édition, fusion/éclatement, …). Nous illustrons nos propositions sur deux cas d’application : la diffusion des thèses de l’INSA de Lyon et la mise en ligne de la Chronique des Fouilles Archéologiques de l’Ecole française d’Athènes. :
Leichte kognitive Beeinträchtigung, demenzielle und depressive Erkrankungen – Besondere Maßnahmen im höheren Lebensalter

Depressionen treten im höheren Lebensalter gehäuft auf und weisen als ei-genständige Krankheitsentitäten verschiedenartige Auftretensformen und klinische Manifestationen auf. Bei älteren Patienten stehen häufig somatische Beschwerden im Vordergrund, die die rechtzeitige Diagnosestellung und Therapie erschweren. Therapieverfahren sollten unter Berücksichtigung der besonderen Anforderungen des älteren Patienten ausgewählt werden. Die leich-te kognitive Beeinträchtigung (LKB) ist mit einem erhöhten Risiko für die spätere Manifestation einer Demenzerkrankung assoziiert. Die unterschiedlichen Konzepte lassen sich hinsichtlich Ätiologie, symptomatischen Schwer-punkten und Verlauf unterteilen. Die Wirksamkeit pharmakologischer Ansät-ze ist bisher nur unzureichend belegt. Primär-und sekundärpräventive Maßnahmen sollten empfohlen werden. Darüber hinaus werden überblicks-artig Demenzen und die wichtigsten diagnostischen Verfahren sowie die Un-terscheidung der Alzheimer-Demenz zu LKB und depressiver Pseudodemenz vorgestellt.
The Perdigão field campaign : evaluation of the Cell Perturbation Method in atmospheric simulations

State-of-the-art modeling methods are used to simulate the flow over highly complex terrain as documented during the 2017 Perdigao Field Campaign (Portugal). A one-way nesting technique in the Weather Research and Forecasting (WRF) model distinguishing four levels is used to capture the broad range of scales of motion. A new coupling strategy, the Cell Perturbation Method (CPM), is adopted and evaluated using the field data of the campaign. To what extent CPM is contributing to the numerical predictions is the main question addressed in this research. Different model configurations are compared and both qualitative and quantitative comparisons are evaluated to demonstrate the contributions of CPM to the overall results. The domain definition is found important and the robustness of CPM is shown by field comparisons. Wind direction comparisons with tower data of eight different towers show a better agreement for towers measuring the mean flow. Wind speed is under-predicted for all the towers and only the average magnitude of the prediction of turbulent kinetic energy (TKE) has a reasonable agreement with some of the tower data. Comparison with a simulations without CPM shows that the inclusion of CPM does not alter the simulated results significantly.
Plasma medicine—current state of research and medical application

Plasma medicine means the direct application of cold atmospheric plasma (CAP) on or in the human body for therapeutic purposes. Further, the field interacts strongly with results gained for biological decontamination. Experimental research as well as first practical application is realized using two basic principles of CAP sources: dielectric barrier discharges (DBD) and atmospheric pressure plasma jets (APPJ). Originating from the fundamental insights that the biological effects of CAP are most probably caused by changes of the liquid environment of cells, and are dominated by reactive oxygen and nitrogen species (ROS, RNS), basic mechanisms of biological plasma activity are identified. It was demonstrated that there is no increased risk of cold plasma application and, above all, there are no indications for genotoxic effects. The most important biological effects of cold atmospheric pressure plasma were identified: (1) inactivation of a broad spectrum of microorganisms including multidrug resistant ones; (2) stimulation of cell proliferation and tissue regeneration with lower plasma treatment intensity (treatment time); (3) inactivation of cells by initialization of programmed cell death (apoptosis) with higher plasma treatment intensity (treatment time). In recent years, the main focus of clinical applications was in the field of wound healing and treatment of infective skin diseases. First CAP sources are CE-certified as medical devices now which is the main precondition to start the introduction of plasma medicine into clinical reality. Plasma application in dentistry and, above all, CAP use for cancer treatment are becoming more and more important research fields in plasma medicine. A further in-depth knowledge of control and adaptation of plasma parameters and plasma geometries is needed to obtain suitable and reliable plasma sources for the different therapeutic indications and to open up new fields of medical application.
Passive Appendages Improve the Maneuverability of Fishlike Robots

It is known that the passive mechanics of fish appendages play a role in the high efficiency of their swimming. A well-known example of this is the experimental demonstration that a dead fish could swim upstream [1]. However, little is known about the role if any of passive deformations of a fishlike body that could aid in its maneuverability. Part of the difficulty investigating this lies in clearly separating role of actuated body deformations and passive deformations in response to the fluid structure interaction. In this paper, we compare the maneuverability of several fish-shaped robotic models that possess varying numbers of passive appendages with a fish-shaped robot that has no appendages. All the robots are propelled by the oscillations of an internal momentum wheel thereby eliminating any active deformations of the body. Our experiments clearly reveal the significant improvement in maneuverability of robots with passive appendages. In the broader context of swimming robots, our experiments show that passive mechanisms could be useful to provide mechanical feedback that can help maneuverability and obstacle avoidance along with propulsive efficiency.
Reconstruction of a Partial Mastectomy Defect with the Superficial Inferior Epigastric Artery (SIEA) Flap

A case in which a superﬁcial inferior epigastric artery (SIEA) ﬂap was used to reconstruct a partial mastectomy defect is described. The SIEA vessels have been shown to be predictable and to match well with the recipient internal mammary vessels. In addition, this ﬂap does not require opening of the anterior rectus sheath, and it is possible to design a smaller ﬂap, which would allow closure at the donor site without translocation of the umbilicus. The risk of developing an abdominal hernia or bulge is therefore nonexistent, and a very low and more inconspicuous scar is produced, both of which are advantages for the patient.
A survey on PCM using Non-Binary Orthogonal Latin Square

This manuscript proposes non-binary orthogonal Latin square (OLS) codes that are amenable to a multilevel phase change memory (PCM). This is based on the property that the proposed (n symbols, k symbols) t-symbol error correcting code uses the same H matrix as an (n bits, k bits) binary t-bit error correcting OLS code. The new codes are shown to have a shorter check bit length and better probability in encoding/decoding than conventional binary OLS codes. Extensive results are provided for assessment and comparison. The proposed codes are also shown to be always better than the matrix codes, i.e. independently of the metric and the parameters employed in the comparison.
Turbulence in space plasmas and beyond

Most of the visible matter in the Universe is in the form of highly turbulent plasmas. For a long time the turbulent character of astrophysical fluids has been neglected and not well understood. One reason for this is the extremely complicated physics involved in astrophysical processes ranging from the machinery of stars, solar and stellar winds, accretion disks to interstellar clouds and galaxies. The other reason is that turbulence constitutes in itself a difficult subject where most of the fundamental results belongs to the incompressible hydrodynamics. Nevertheless, significant theoretical progress has been made during the last years to incorporate some ingredients like compressibility or small-scale plasma physics which are fundamental in astrophysics. This paper reviews some of these results with a strong focus on space plasmas (solar wind, solar corona). Turbulence in interstellar clouds (supersonic flows) and cosmology (space-time fluctuations) are also briefly mentioned.
LPV Static Output Feedback for Constrained Direct Tilt Control of Narrow Tilting Vehicles

This brief presents a new direct tilt control (DTC) design to improve the lateral stability and the driving comfort of narrow tilting vehicles. To this end, a conceptual model is constructed from the vehicle dynamics, a simplified model of the driving environment, and the vehicle perceived acceleration. This latter is considered as the main performance variable of the related <inline-formula> <tex-math notation="LaTeX">$\mathcal {H}_{2}$ </tex-math></inline-formula> control problem. The conceptual model is then represented in a polytopic linear parameter varying (LPV) form for control purposes. To avoid the use of costly vehicle sensors while favoring the simplest control structure for real-time implementation, a new LPV static output feedback control method is proposed. Thanks to Lyapunov stability arguments, physical constraints on both system states and DTC actuator are <italic>explicitly</italic> considered in the design procedure to improve the safety and the comfort of passengers. Moreover, a parameter-dependent Lyapunov function is exploited for theoretical developments. In this way, the <italic>finite</italic> bounds on vehicle speed and acceleration are effectively taken into account in the control design to reduce the conservatism. The <inline-formula> <tex-math notation="LaTeX">$\mathcal {H}_{2}$ </tex-math></inline-formula> control design is recast as a linear matrix inequality-based optimization which can be easily solved with numerical solvers. The resulting robust DTC controller is evaluated with realistic driving scenarios.
Pregabalin Does Not Impact Peripheral Nerve Regeneration after Crush Injury

Timely repair and robust regeneration after traumatic peripheral nerve injury are essential to ensure optimal recovery. Pregabalin (Lyrica; Pﬁzer Inc., Morris Plains, NJ), frequently prescribed to attenuate neuropathic pain in patients with traumatic nerve injury, was evaluated for its potential to alter nerve regeneration in the rat sciatic crush model. Rats were randomly assigned to one of three groups of 12 animals each: (1) sham surgery and pregabalin injections; (2) crush injury and pregabalin injections; and (3) crush injury and saline vehicle injections. Nerve regeneration was evaluated with weekly walking tracks and histomorphometry. There were no signiﬁcant differences in sciatic function index or histomorphometric parameters at the 21-day endpoint between the pregabalin-treated rats undergoing crush injury and the saline-treated controls. Although we have observed a subjectively improved clinical course in human patients treated with pregabalin after traumatic nerve injury, the effect does not appear to be due to accelerated nerve regeneration.
lnvasive Growth Patterns of Hepatic Hilar Ductal Carcinoma

Background. Postoperative recurrence of hepatic hilar ductal carcinoma usually occurs in a localized region around the surgical margin, such as the bile duct. This study was aimed at assessing the invasive patterns of the hepatic hilar ductal carcinoma by histologically examining surgical specimens obtained by extended liver resection, especially the involvement of intrahepatic duct. Methods. Eighteen resected specimens of hepatic hilar ductal carcinoma were histologically investigated. Multiple sections vertical to the extrahepatic and intrahepatic bile duct were made at a 5-mm interval. The extension of carcinoma was evaluated on each of three layers (mucosal, extramucosal-intramural, and extramural), and routes of the invasion were examined. Results. Extramucosal extent toward the hepatic side was observed in 14 patients (77.8%) and that toward the duodenal side in 8 patients (44.4%) (P < 0.05). The distance ofextramucosal tumor extent was also significantly longer (P < 0.05) in the hepatic side than in the duodenal side. Histologic tumor margin was usually identified in the extramural layer. Two patients had discontinuous extramucosal invasion. The lymphatic invasions were observed most frequently, followed by perineural invasion, and venous invasion was rare. In the extramucosal invasion of the liver, the left dominant carcinomas had extended toward the left, whereas those right dominant had extended toward the right (P < 0.05). Well differentiated tubular adenocarcinomas extended to the liver more extensively than moderately and poorly differentiated ones, but not significantly. Conclusions. The authors examined the extramucosal invasion of hepatic hilar ductal carcinoma. This inva-
Basal Ganglia and Its Relevance to Parkinson’s Disease

The recent availability of selective ligands for NMDA and AMPA receptors has enabled neuroscientists to test the hypothesis that Parkinson’s disease is a glutamate hyperactivity disorder and hence treatable with glutamate antagonists. This review takes a critical look at the motor characteristics of this new class of drugs in rodent and primate models of parkinsonism and assesses the clinical potential and pitfalls of this radical new approach. Monotherapy of Parkinson’s disease with glutamate antagonists appears impractical a t the present time, due to their low efficacy and unacceptable side effects, but polypharmacy with L-DOPA and a glutamate antagonist as adjuvant is a more realistic prospect. This review will focus on the ways in which glutamate receptor blockade facilitates motor recovery with L-DOPA and will examine whether the basis for this beneficial effect can be traced to a specific interaction with dopamine at D, or D, receptors, and therefore to discrete motor pathways within the basal ganglia. o 1995 Wiley-Liss, Inc.
Preparation of Pt/ZIF-7 hybrid porous material and its application in hydrogen fuel cell

Hydrogen fuel cell vehicles are the most ideal low-carbon and environmentally friendly new energy vehicles, but the catalyst for hydrogen fuel cells requires the use of precious metal platinum. At present, the catalysts for hydrogen fuel cells mainly rely on imports, greatly limiting the development of hydrogen fuel cell vehicles in China. We used a simple and energy-saving room temperature stirring method to in-situ load polyvinyl pyrrolidone modified Pt onto ZIF-7, so that the surface of ZIF crystal can continuously absorb PVP modified Pt nanoparticles while growing. PVP is a non-ionic surfactant, which can not only stabilize Pt nanoparticles in polar solvents, but also control the size and shape of Pt nanoparticles as a capping agent. This can not only avoid the agglomeration of Pt nanoparticles to keep their original characteristics, but also effectively control the spatial distribution of Pt nanoparticles in ZIF-7. The catalysts Pt/ZIF-7 were prepared, with corresponding Pt content of 0.052%, 0.26%, 0.52%, and 1.04%, respectively. Subsequently, we will apply the prepared Pt/ZIF-7 catalyst to hydrogen fuel cells and test its catalytic performance.
Another deep dimming of the classical T Tauri star RW Aur A ? (Research Note)

Context. RW Aur A is a classical T Tauri star (CTTS) with an unusually rich emission line spectrum. In 2014 the star faded by 3 magnitudes in the V band and went into a long-lasting minimum. In 2010 the star su ered from a similar fading, although less deep. These events in RW Aur A are very unusual among the CTTS, and have been attributed to occultations by passing dust clouds. Aims. We want to find out if any spectral changes took place after the last fading of RW Aur A with the intention to gather more information on the occulting body and the cause of the phenomenon. Methods. We collected spectra of the two components of RW Aur. Photometry was made before and during the minimum. Results. The overall spectral signatures reflecting emission from accretion flows from disk to star did not change after the fading. However, blue-shifted absorption components related to the stellar wind had increased in strength in certain resonance lines, and the profiles and strengths, but not fluxes, of forbidden lines had become drastically di erent. Conclusions. The extinction through the obscuring cloud is grey indicating the presence of large dust grains. At the same time, there are no traces of related absorbing gas. The cloud occults the star and the interior part of the stellar wind, but not the wind/jet further out. The dimming in 2014 was not accompanied by changes in the accretion flows at the stellar surface. There is evidence that the structure and velocity pattern of the stellar wind did change significantly. The dimmings could be related to passing condensations in a tidally disrupted disk, as proposed earlier, but we also speculate that large dust grains have been stirred up from the inclined disk into the line-of-sight through the interaction with an enhanced wind.
Expression in ProstateCancerCells:TheRole of Bone Microenvironment-AssociatedCXCL12

BACKGROUND. Hematopoietic cells home to bone bymeans of chemo-attraction to marrow chemokines, and interaction of chemokines with their receptors leads to the expression/ activation of adhesion molecules and proteases. Recent evidence suggests that similar mechanisms may be active in cancer metastasis. Previously, we showed that metalloproteases (MMPs), and in particular MMP-9, play a role in prostate cancer (PC) expansion in bone. METHODS. Weusedavariety ofmethods includingRT-PCR, immunohistochemistry, ELISA, gelatin zymography, cellular motility and invasion, and subcellular fractionation of PC cells applied to in vivo and in vitro models. RESULTS. Here we showed that (a) CXCL12/CXCR4 axis is expressed in PC bonemetastasis; (b) exogenous CXCL12 inducedMMP-9 expression by PC cells; (c) bone stromal cells and bone tissue conditioned media induced the migration of PC cells in a CXCR4-dependent manner; (d) pharmacological inhibition of PI3 kinase and MAP kinase pathways abrogated CXCL12induced MMP-9 expression and invasion of PC cells; (e) exogenous CXCL12 induced Akt1 phosphorylation is indispensable for proMMP-9 secretion, migration, and invasion of PC cells; (f) CXCR4 was localized to lipid rafts in PC cells and initiated Akt phosphorylation. CONCLUSIONS. These data suggest that chemoattractive mechanisms involve migration of cancer cells towards bone tissue, and that cell signaling induced by binding of the chemokine to its receptor leads to the activation of multiple signaling pathways and subsequent secretion of MMP-9 into the local environment. These findings provide a link between chemoattractive mechanisms, growth of tumor cells in bone, and tumor-enhancedbonematrix turnover.Prostate 66: 32–48, 2006. # 2005 Wiley-Liss, Inc.
Global approximation based adaptive RBF neural network control for supercavitating vehicles

A global approximation based adaptive radial basis function (RBF) neural network control strategy is proposed for the trajectory tracking control of supercavitating vehicles (SV). A nominal model is built firstly with the unknown disturbance. Next, the control scheme is established consisting of a computed torque controller (CTC) for the practical vehicle and an RBF neural network controller to estimate model error between the practical vehicle and the nominal model. The network weights are adapted by employing a Lyapunov-based design. Then it is shown by the Lyapunov theory that the trajectory tracking errors asymptotically converge to a small neighborhood of zero. The control performance of the proposed controller is illustrated by simulation.
AND T

Forty-five patients with inoperable cancer of the liver were treated by the one shot administration of 15-40 mg of Mitomycin C into the hepatic artery, either by the superselective or by the selective ofie shot method. Fourteen of the patients had primary cancers of the liver, and 31 had metastases to the liver from primary cancers of the stomach, or from the colorectal or other organs. Subjective symptoms improved in 7370, and objective signs improved in 60%. Nineteen patients who received this treatment more than twice showed a mean survival time of 10 months and a 50% survival time of 7.8 months. Therapeutic effects of the selective one shot method were recognized mostly in patients with tumors which were rich in vessels. However, a fairly good result was obtained using the superselective one shot method, even in patients with tumors having relatively few vessels. Cancer 41:1720-1727, 1978.