Miracle-dz/UniFAR-FTUs huggingface dataset:
Transforming people practices by re-structuring job engagement practices for generation z: An empirical study

Purpose This paper aims to develop the readers’ understanding of the transforming role of job engagement (JOB) drivers, specifically for Gen Z in information technology (IT) Companies across India. It measures the association of JOB and perceived organizational support (POS), perceived supervisor support (PSS) and co-worker relationship (COP) with a very special reference to Gen Z. Design/methodology/approach A total of 302 survey-based responses were collected. To test the conceptualized model of JOB, structural equation modeling was used. Confirmatory factor analysis was conducted using the AMOS platform toward determining the reliability and validity of the individual constructs and the overall model. Findings All three dimensions, namely, POS, PSS and COP, are positively related to JOB. Out of the three, the most contributing extent in engaging Gen Z is PSS. Research limitations/implications A conceptual framework of Gen Z engagement drivers could help human resource (HR) researchers fine-tune Gen Z employees’ retention strategy. The paper shows that it is not about pandering to them but about eliminating blocks so that Gen Z can deliver the future business. Practical implications The outcomes may aid establishments and policymakers in advancing and improving HRs policies in engaging Gen Z, who have started entering the organizations. Originality/value JOB practices can add to the determinations of the HRs processes in the IT start-ups organizations in dealing with Gen Z. This research reconnoiters the drivers of engagement strategies directly impacting JOB Gen Z.
The Genetic Variants of HLA-DRB1 Alleles and the Chance of Developing Rheumatoid Arthritis: Systematic Review and meta-analysis

Rheumatoid arthritis (RA) is more common in those who have special human leukocyte antigen (HLA) genetic types. One of the most important genetic risk factors for RA lies in HLADRB1 locus. The purpose of this meta-analysis was to figure out which HLA-DRB1 allele frequencies are associated with a risk of RA per allele and phenotype group. The statistics data was calculated using RevMan version 5.4. 1. This meta-analysis includes nine articles involving 3004 RA patients and 2384 healthy controls. In the allele group, three HLA-DRB1 alleles; HLA-DRB1*10 (OR = 1.88, 95%CI = 1.25-2.83, p = 0.002), HLA-DRB1*04 (OR = 2.38, 95%CI = 1.73-3.29, p < 0.00001), and HLA-DRB1*01 frequencies were shown to be considerably higher in RA patients compared to controls, potentially increasing the chance of disease development. Four HLA-DRB1 alleles among the included studies (*03, *07, *11, *13, and *14) which was observed that these are more prevalent in healthy persons than in RA patients, and may contribute as a protective factor against disease onset. Only the DRB1*04 subtypes DRB1*0401 (OR = 1.37, 95 percent CI = 1.05-1.79, p = 0.02) and DRB1*0404 (OR = 1.73, 95% CI = 1.19-12.53, p = 0.004) show a significant association with the risk of RA in our pooled effect. Moreover, the findings demonstrated a significant relationship between HLA-DRB1 and the risk of disease in various ethnic groups.
Valleytronic and magneto-optical properties of Janus and conventional 
TiBrI/CrI3
 and 
TiX2/CrI3
 
(X=Br,I)
 heterostructures

We report magnetic proximity effect, valley splitting (VS), and magneto-optical properties of polar $(\mathrm{TiBrI}/\mathrm{Cr}{\mathrm{I}}_{3})$ and nonpolar ($\mathrm{Ti}{X}_{2}/\mathrm{Cr}{\mathrm{I}}_{3}$, $X=\mathrm{Br},\mathrm{I}$) magnetic van der Waals heterostructures. To properly handle many-body effects, the band structure and excitonic effects are considered on the same footing by carrying out first-principles calculations together with resolving the Bethe-Salpeter equation. We find that an atypical type-III band alignment leads to a sizable magnetic proximity effect as well as giant VS (126 meV). In addition, they can be largely tuned by the polarity of TiXY crystal structure and stacking configuration. Moreover, such a giant magnetic proximity effect drives a switch of spin-band (spin-up and spin-down) ordering of TiBrI, not only in the conduction band, but also surprisingly in the valence band in the vicinity of $K$ or $K$\ensuremath{'} points, which brings out a significant change in exciton emissions. Our results open an avenue for spintronics and nano-optics applications.
Health Care Experiences of Patients with Nonbinary Gender Identities.

Purpose The primary purpose of this study was to characterize the health care experiences of diverse patients with nonbinary gender identities across a range of geographic locations. A secondary aim was to use the qualitative findings to inform recommendations for clinics and providers to create gender-affirming health care environments for nonbinary patients. Methods We conducted 3 focus group discussions with 7-9 participants, for a total of 24 unique participants. To be eligible, participants were required to be 18 years of age or older, live in the United States, speak English, have the ability to access Zoom in a private room, have a nonbinary gender identity, and be able to attend one of three scheduled focus groups. Results Participants reported frequent negative health care experiences, including misgendering, invalidation, and pathologization, even within clinics that signaled alliance with transgender communities. Participants described strategies they use to cope with negative experiences, including health care avoidance, identity concealment, and seeking out providers that are matched in terms of gender minority status and/or race. Conclusion Recommendations for the provision of gender-affirming health care for nonbinary patients include nonbinary-inclusive intake forms and electronic health records, having providers be proactive in eliciting preferred names and pronouns, and requiring education for providers and staff at all levels on the provision of nonbinary-inclusive gender-affirming health care.
Negotiating Multiple Identities of Brazilian Paralympians

In this article, I draw on the personal narratives of 41 Brazilian Paralympic athletes who competed in the 2016 Rio Paralympic Games to explore their multiple identities shaped within and outside sport and how they negotiated those self-representations. Parathletes’ narratives gave a sense of who they are, how they live their lives, and what their struggles, hopes, and aspirations are within and outside sport. The available studies in disability sport and the representation of disabled athletes have largely failed to examine the stories of these individuals and address their unique realities and perspectives. Five major themes emerged from the interview analysis regarding the parathletes’ self-representation: athletic identity, gender identity, disability identity, national identity, and activist identity. These accounts also revealed how these individuals negotiated their multiple identities in different settings and the tensions they experienced in their social interactions. The Rio Paralympics presented such a new interaction setting for the Brazilian parathletes who competed on such a grand scale at home for the first time and provided multiple examples in the athletes’ accounts of their identities.
Position artifacts in 3D reconstruction of plate‐shaped precipitates in steels depending on the analysis direction of atom probe tomography

Atom probe tomography (APT) analysis often produces artifacts in atomic position owing to the difference in evaporation fields in materials. The atomic density profiles of grain boundaries, plate‐shaped low‐field precipitates (cementite), and high‐field precipitates (vanadium carbide) in steels were investigated via two analyses in directions perpendicular and parallel to the boundaries and platelets. Although the perpendicular analysis indicated better quantitative performances in the composition analyses of segregating atoms at the grain boundary and the constituent atoms of the precipitates, an abnormal atomic density was observed around the interfaces of the precipitates. Geometric calculation using a two‐radius model based on the local magnification effect suggested that a spike structure at the front interface and a dip structure at the rear interface for lamellar cementite correspond to an overlap and a gap in the evaporated atoms from the cementite and matrix, respectively. This indicates that even in the perpendicular analysis, the precipitate constituent atoms and matrix atoms mixed in the depth direction. We discuss the origin and impact of the position artifacts in the perpendicular analyses of low‐ and high‐field plate‐shaped precipitates and also discussed the application limits of the model.
Two Dimensional Magnetic Coordination Polymers Formed by Lanthanoids and Chlorocyananilato

Here we show the important role played by the size of the lanthanoid and the solvent used in the final structures of several two-dimensional magnetic coordination polymers with the ligand chlorocyananilato, (C6O4(CN)Cl)2−. With this aim we have prepared five compounds: [Nd2(C6O4(CN)Cl)3(DMF)6] (1) (DMF = dimethylformamide), [Dy2(C6O4(CN)Cl)3(DMF)6]·4H2O (2), [Ho2(C6O4(CN)Cl)3(DMF)6]·2H2O (3), and [Ln2(C6O4(CN)Cl)3(DMSO)6] with Ln = Ce (4) and Nd (5) (DMSO = dimethylsulfoxide). These compounds are formed by two dimensional networks with a (6,3)-topology but, depending on the size of the lanthanoid and on the solvent used, show important structural differences, including the size, shape, distortion and content of the cavities as well as the flatness of the layers. The comparison of compounds 1–3 and 4–5 shows the role played by the size of the lanthanoid while keeping constant the solvent, whereas, the comparison of compounds 1 and 5 shows the role of the solvent (DMF vs. DMSO) while keeping constant the lanthanoid. The magnetic properties of all of them show the absence of noticeable magnetic interactions, in agreement with previous results that can be explained by the internal character of the 4f electron and the weak magnetic coupling mediated by these anilato-based ligands.
Image Denoising Using Multiwavelet Transform with Different Filters and Rules

Image denoising is a technique for removing unwanted signals called the noise, which coupling with the original signal when transmitting them; to remove the noise from the original signal, many denoising methods are used. In this paper, the Multiwavelet Transform (MWT) is used to denoise the corrupted image by Choosing the HH coefficient for processing based on two different filters Tri-State Median filter and Switching Median filter. With each filter, various rules are used, such as Normal Shrink, Sure Shrink, Visu Shrink, and Bivariate Shrink. The proposed algorithm is applied Salt& pepper noise with different levels for grayscale test images. The quality of the denoised image is evaluated by using Peak Signal to Noise Ratio (PSNR). Depend on the value of PSNR that explained in the result section; we conclude that the (Tri-State Median filter) is better than (Switching Median filter) in denoising image quality, according to the results of applying rules the result of the Shrinking rule for each filter shows that the best result using first the Bivariate Shrink.
Milk Fermented with Lactobacillus casei Strain AP Improves Lipid Profiles in Obese Indonesian Adults

Obesity and hyperglycemia can trigger various diseases, including diabetes mellitus and cardiovascular ailments. Health-promoting fermented milk products can be useful in tackling these issues. One such product is the fermented milk developed using Lactobacillus casei AP, a probiotic strain from Indonesia that has not been tested in humans thus far. Our objective was to examine the effects of L. casei AP-fermented milk products on lipid profiles, blood glucose levels and monocyte chemoattractant protein-1 (MCP-1) levels in obese adults. A total of 29 obese subjects were given L. casei AP-fermented milk products, and their fasting blood glucose, total cholesterol, low-density lipoprotein (LDL), high-density lipoprotein (HDL) and triglyceride levels were measured using diagnostic system kits. MCP-1 levels were measured using enzyme-linked immunosorbent assay. It was determined that the administration of L. casei AP-fermented milk products significantly reduced total cholesterol, LDL and triglyceride levels (p < 0.05); however, it did not increase HDL (p > 0.05), MCP-1 or fasting blood glucose levels (p ≥ 0.05). In conclusion, in obese Indonesian adults, L. casei AP-fermented milk might reduce total cholesterol, LDL and triglyceride levels but may not affect HDL, MCP-1 or fasting blood glucose levels.
Usnea filipendula Induces Apoptosis in Human Colon Cancer Cell Lines

Lichens are complex organisms living in a symbiotic relationship with fungi and algae have recently received special interest in cancer research. The cytotoxic activities of Usnea filipendula Stirt. lichen extract was investigated on colon cancer cell lines, HCT-15 and HT-29. Sulforhodamine B and ATP cell viability tests were used to monitor cytotoxic activity. The mode of cell death (apoptosis/necrosis) was determined using caspase-cleaved cytokeratin 18 (M30), caspase-3/7 activity and fluorescence staining techniques that included, Annexin-V, Hoechst 33342 and propidium iodide. Usnea filipendula showed dose and time-dependent antiproliferative effect in HCT-15 and HT-29 cells. The IC50 values in HCT-15 and HT-29 cells were 17.92 and 41.87 µg/ml, respectively. The extract induced apoptosis in both cell lines especially in HCT-15 cells in which caspase-3/7 activity was increased. Usnea filipendula was cytotoxic to colon cancer HCT-15 and HT-29 cell lines by inducing early or late apoptosis as evidenced by translocation of phosphatidylserine, pyknotic nuclei and nuclear condensation. Further studies would help to understand the full potential of Usnea filipendula as a novel anticancer therapy.
Dual signal insight: field-efficient qualitative/quantitative detection of sulphamethazine in raw milk

ABSTRACT A novel lateral flow assay (LFA) was developed by introducing magnetic beads with colloidal gold nanoparticles (AuMB) to LFA test strips for the qualitative and quantitative detection of sulphamethazine (SM2) in raw milk. In the proposed assay, test samples are qualitatively judged yes (positive) or no (negative) on the basis of naked-eye signals from the colloidal gold and fluorescence quenching is used to quantitatively determine the level of SM2 in positive samples. Results indicated that the threshold concentration for determining whether a test sample is positive or negative is 5 ng/mL. The limit of detection and linear range of the proposed AuMB–LFA for quantitative detection were 0.39 and 0.5–200 ng/mL, respectively, and its recovery for detecting SM2 in raw milk was 97.4–110.2%. The developed AuMB–LFA provides novel insights into efforts to maintain a balance between the efficient screening of targets in large samples and saving time and money. GRAPHICAL ABSTRACT
Machine-learning integrated glassy defect from an intricate configurational-thermodynamic-dynamic space

Optimizing materials' properties and functions by controlling defects in the crystalline phase has been a cornerstone of materials science and condensed matter physics. However, this paradigm has yet to be established in the broadly defined amorphous materials, which implies the identification of very subtle structural features in an otherwise uniformly disordered medium. Here we propose and define a new integrated glassy defect (IGD), based on machine learning strategy informed by atomistic physics, and also by an extremely wide configurational, thermodynamic, and dynamic variables space of the disordered state. The IGD simultaneously includes positional topology and vibrational features, as well as the local morphology of the potential energy landscape. This unprecedented combination gives rise to a much more comprehensive and more effective definition of the ``glassy defect,'' much beyond the conventional, purely structural input. IGD can be used not only as an efficient predictor of athermal plasticity but is also transferable to detect both short-time vibrational anomalies (the boson peak), and long-time relaxation and diffusion dynamics in glasses. The integrated strategy is instrumental to build the long-sought structure-property relationship in complex media.
Rejuvenating the rewards typology: Qualitative insights into reward preferences

For many people, work is no longer a choice. People draw on their earnings to uphold basic survival needs, live comfortably, pursue recreational activities and in general, afford characteristics of the modern lifestyle (Cosma & Gilceava, 2014; Javid & Chapa, 2014; Pasztor & Valent, 2016; Yao, Parker, Arrowsmith, & Carr, 2017; Yousaf, Latif, Aslam, & Saddiqui, 2014). Although the importance of pay cannot be overstated, the idea that employees merely seek money from what they do is not necessarily true. Whilst financial rewards may be used to satisfy the basic needs of employees as well as attract and retain top talent (Alhmoud & Rjoub, 2019; Osibanjo, Adeniji, Falola, & Heirsmac, 2014; Terera & Ngirande, 2014), research has concluded that alone, it is not a sustainable motivational solution to driving their finest performance (Kulchmanov & Kaliannan, 2014; Mundhra & Jacob, 2011) or overall, satisfaction with their jobs (Akafo & Boateng, 2015; Huang, 2016; Ollar & Uwakwe, 2020). In fact, financial rewards are only ‘part of the parcel’ in one’s working life and not enough for organisations to harness long-term employee motivation and enthusiasm (Kathombe, Kipchumba, & Kirui, 2018; Mokhniuk, 2016; Mundhra & Jacob, 2011; Singh, 2016).
Health status of people with autism spectrum disorder

Purpose The aim of this study is to determine what changes occur in the health status of people with autism spectrum disorder (ASD) compared to neurotypical controls. Design/methodology/approach The authors performed a comparative analysis of data collected from 72 subjects with ASD and 75 neurotypical controls aged 3–24 years using the Rochester Health Status Survey IV (RHSS-IV). A structured individual interview was conducted to compare the health status of subjects in Macedonia. Findings A majority of people with ASD take vitamins, supplements and use recommended drug therapies compared to the neurotypical population and experience a larger number of side effects (p = 0.000). Compared to people with neurotypical development, children with ASD have a higher prevalence of oral ulcers (31.9% vs 17.3%; p = 0.039), changes in neurological health status – epilepsy (19.4% vs 2.7%; p = 0.001) and ADD/ADHD (only persons with ASD-19.4%; p = 0.000); respiratory diseases – angina (30.5% vs 8%; p = 0.000), rhinitis and/or sinusitis (40.3% vs 17.3%; p = 0.02); changes in the gastrointestinal system – constipation (31.9% vs 10.6%; p = 0.02), intestinal inflammation (19.4% vs 8%; p = 0.043), permeable intestines (only persons with ASD – 13.9%; p = 0.000) and the presence of the fungus Candida albicans (19.4% vs 4%; p = 0.043); psychiatric disorders – sleep problems (only in people with ASD – 18%; p = 0.000) and tics (6.9% vs 2.6%; p = 0.25) and skin diseases – eczema/allergic skin rash (36.1% vs 18.7%; p = 0.02). Originality/value Many children with ASD have health problems. These findings support and complement the professional literature on their mutual causality.
Cryptostegia Madagascariensis Alters the Litterfall and Nutrient Cycling of Litter Inputs in An Invaded Tropical Cambisol From North-Eastern Brazil

The invasive Cryptostegia madagascariensis occupies riparian areas covered by tropical Cambisols throughout the North-eastern Brazil however litter is known regarding its ability to impact litter inputs, and ecosystem processes. This study aimed to characterize the effects of the invader on the litter deposition, soil physical-chemical properties, litter nutrient content, and the litter decay rate in a Tropical Cambisol. Comparisons of native and invaded environments showed that C. madagascariensis alters the quantity of litter deposition during both dry and rainy seasons. In contrast to native species, C. madagascariensis litterfall displayed litter seasonal variation (rainy vs. dry season), however invaded sites had higher litter biomass compared to native sites. C. madagascariensis litter was enriched in soil organic matter, N, P, and K contents as compared to the native litter. Compared to native environments, invaded ones had significantly decreased soil temperature and soil water content. Results suggest that C. madagascariensis enhances litter and N, P, and K availability in ways that have potential to impact soil ecosystem in the Tropical Cambisols from Caatinga ecoregion, Brazil.
Effect of Histone Deacetylase (HDAC) Inhibitor on Gene Expression in LNCaP-MST and MCF-7 Cells

Histone Deacetylases (HDACs) are evolving as key enzymes in many physiological processes, including chromatin remodeling, genome stability, DNA repair, regulation of transcription, metabolism, protein secretion and cell cycle progression. In the cellular systems there is a balance between deacetylation and acetylation which controls gene transcription. The HDACs catalyse the elimination of the acetyl moiety from the lysine residues of proteins, as well as the core nucleosomal histones. Through removal of critical acetyl groups from the histones, HDACs can generate a chromatin conformation that can prevent the transcription of genes that encode for proteins involved in cell cycle regulation. In many cancer cell lines, overexpression or activation of the HDAC enzymes results in histone hypo-acetylation and following promotion of pro-cancerous mechanisms. Therefore, HDAC inhibitors represent a potential new class of anti-tumor agents with cytotoxic activity and the ability to regulate gene expression in tumor cells. In the present study, we evaluated the effects of SAHA (Suberoylanilide Hydroxamic Acid), which is a potent inhibitor of HDAC, on cell cycle regulation in LNCaP-MST cells (MDM2 overexpressing prostate cancer cells) and MCF-7 (MDM2 expressing breast cancer cells). The gene expressions analyzed through qRT-PCR, RT-PCR and western blot of LNCaP-MST and MCF-7 cells, after treating with SAHA (7.5 μm), were able to trigger p21 protein expression. In this study, SAHA seems to be inducing the p21 expression in a p53 independent manner. Our results confirm that SAHA treatments could significantly up and down-regulate some of the key genes and proteins such as p21 that modulate cancer cell growth. In the LNCaP-MST cells, AURKB (Aurora Kinase B), CDC25C (Cell Division Cycle 25C), and CDK1 (Cyclin-Dependent Kinase 1) protein expressions were down-regulated, which may impact the G1 or G2/M phase cell cycle arrest and suppression of cancer growth. Our results with LNCaP-MST cells offer convincing evidence to suggest that the inhibition of HDAC can control proliferative cell signals.