Miracle-dz/UniFAR-FTUs huggingface dataset:
Etude expérimentale et numérique de la propagation d'ondes de gravité en zone de déferlement

En zone littorale, la houle subit de fortes transformations par effets bathymetriques. Une meilleure comprehension de ses modifications et des transferts d'energie associes permet de mieux apprehender les problemes de dimensionnement de structures cotieres et d'amenagement du littoral (protection du littoral, influence des ouvrages sur la cote). L'objectif de ce travail est d'etudier experimentalement et numeriquement la propagation et le deferlement d'ondes de gravite. La premiere partie, experimentale, propose des methodes de calcul, basees sur les houles de Stokes, pour la mesure d'ondes partiellement stationnaires a partir d'instruments de type electromagnetique (S4) ou acoustique (ADV) donnant des mesures synchrones de vitesses et/ou de pression. Les influences du courant, de la direction de propagation, de la profondeur d'immersion des appareils ainsi que des effets non lineaires sont alors etudies a partir de donnees en bassin et in situ. La deuxieme partie, numerique, consiste en la validation d'une methode de suivi de surface libre de type SL-VOF (Semi-Lagrangian Volume Of Fluid), inseree dans un code de calcul industriel (code EOLE de la societe Principia R&D). L'onde de gravite est modelisee par un soliton. L'etude de la propagation et du deferlement du soliton est effectuee pour deux applications : sur une marche (discontinuite du fond) puis sur un fond de pente constante 1/15. L'evolution de la surface libre, son elevation et le champ de vitesses sont alors compares aux resultats experimentaux.
A correlation between GALEX FUV magnitude and chromospheric activity among red giant stars – CORRIGENDUM

The version of Equation (1) that was used to transform Fmgii to (Fmgii/Fbol) had an incorrect unit conversion, with the result that the computed values of log (Fmgii/Fbol) are too small by a constant factor of 3.0 dex. As a result this factor of 3.0 needs to be added to the vertical axis scale in Figures 2, 3, and 13, and the horizontal axis scale in Figures 8, 10 and the lower panel of Figure 7. The morphology of the figures is otherwise unchanged. For completeness, accurately-labelled versions of these figures are included with this Corrigendum.
Current Treatment Strategies for Inflammatory Bowel Disease Patients at the Risk of Developing Cancer: A Comprehensive Review

Abstract Inflammatory bowel disease (IBD) is a chronic condition that affects the digestive tract and can lead to inflammation and damage to the intestinal lining. IBD patients with cancer encounter difficulties since cancer treatment weakens their immune systems. A multidisciplinary strategy that strikes a balance between the requirement to manage IBD symptoms and the potential effects of treatment on cancer is necessary for effective care of IBD in cancer patients. To reduce inflammation and avoid problems, IBD in cancer patients is often managed by closely monitoring IBD symptoms in conjunction with the necessary medication and surgical intervention. Anti-inflammatory medications, immunomodulators, and biologic therapies may be used for medical care, and surgical options may include resection of the diseased intestine or removal of the entire colon. The current study provides a paradigm for shared decision-making involving the patient, gastroenterologist, and oncologist while considering recent findings on the safety of IBD medicines, cancer, and recurrent cancer risk in individuals with IBD. We hope to summarize the pertinent research in this review and offer useful advice.
Do Children with Autism Benefit from Educational Interventions Utilizing a Tangible Interface and Audio-augmented Drawings?

In this article, we describe the development and pilot study of an audio-augmented paper drawing system which assists therapy and educational treatment for children with autism spectrum condition (ASC). We used a generative design and dynamic development method to create a system enabling paper drawings to be augmented with an audio recording of a child's voice. The system was found to support therapists in stimulating children's narrative and descriptive development. One significant finding of this work could be that hearing their voice incentivizes children to maintain their attention on comparative narration tasks. Similar audio-augmented paper drawing technologies might be used within rehabilitative and educational settings to assist children with ASC. This article reports the benefits and limits of using audio-augmented paper drawing for the educational treatment of children with ASC.
The characteristic large‐scale annual analysis by gender and age in heart failure patients: cohort for 10 years in Korea

The prevalence and incidence rate of heart failure (HF) continues to increase along with the aging of the population and the increase of ischaemic heart disease. The morbidity and mortality of HF are also on the rise in the industrialized countries; it can be a great public health problem. A detailed and accurate analysis of the demographical incidence and prevalence of HF is an important first step in predicting the occurrence of the disease in the future and proper preparing for prevention. Here, we aimed to analyse the annual prevalence and incidence of HF by gender and age using long‐term national health insurance service data in the Republic of Korea.
Duration of antifungal treatment in mold infection: when is enough?

Purpose of review Although invasive mold infections (IMI) are a major complication in high-risk populations, treatment duration has not yet been well defined. Recent findings Guidelines suggest documenting clinical/radiological resolution and immunological recovery before stopping antifungal treatment, after a minimum duration of treatment of 3 months for invasive pulmonary aspergillosis, while longer (up to 6 months) duration is proposed for the treatment of invasive mucormycosis. However, data on and definitions of clinical/radiological resolution and immune recovery remain scarce. Limited real-life data suggest that often much longer courses of treatment are given, generally in the context of continuous immunosuppression, occasionally defined as secondary prophylaxis. However, clearcut definition and distinction of secondary prophylaxis from antifungal treatment remain to be defined. Summary Decisions to stop antifungal treatment are based on poorly defined treatment responses and immune reconstitution and experts’ opinions. More evidence is needed to determine the optimal duration of treatment of IMI. Well designed, easy to use, and realistic algorithms to help clinicians decide when to stop antifungal treatment are urgently needed.
Face your fears: direct and indirect measurement of responses to looming threats

ABSTRACT This study investigated the emotional and behavioural effects of looming threats using both recalled (self-reported valence) and real-time response measurements (facial expressions). The looming bias refers to the tendency to underestimate the time of arrival of rapidly approaching (looming) stimuli, providing additional time for defensive reactions. While previous research has shown negative emotional responses to looming threats based on self-reports after stimulus exposure, facial expressions offer valuable insights into emotional experiences and non-verbal behaviour during stimulus exposure. A face reading experiment examined responses to threats in motion, considering stimulus direction (looming versus receding motion) and threat strength (more versus less threatening stimuli). We also explored the added value of facial expression recognition compared to self-reported valence. Results indicated that looming threats elicit more negative facial expressions than receding threats, supporting previous findings on the looming bias. Further, more (vs. less) threatening stimuli evoked more negative facial expressions, but only when the threats were looming rather than receding. Interestingly, facial expressions of valence and self-reported valence showed opposing results, suggesting the importance of incorporating facial expression recognition to understand defensive responses to looming threats more comprehensively.
Asymmetries among Person Indexes in Kawahíva

Several Tupí-Guaraní languages have a set of indexes for the subject argument and one set of indexes for the object argument. Previous discussions of these markers have not reached a consensus. Some works have suggested that subject markers are inflectional, but object markers are pronominal (e.g., Cardoso 2008 for Kaiowá, a.o.). An alternative approach, however, suggests through notational choices that both sets are inflectional (Gregóres and Suárez 1967 for Paraguayan Guaraní). This paper draws on original data from Kawahíva and documents asymmetries found in patterns of i) NP and index co-occurrence, ii) reduplication, and iii) root allomorphy between subject indexes (here called Set A) and object indexes (called Set B). I argue the differences between the two sets follow straightforwardly in the former view, which claims that Set A is inflectional and Set B is pronominal.
Smart capsules for sensing and sampling the gut: status, challenges and prospects

Smart capsules are developing at a tremendous pace with a promise to become effective clinical tools for the diagnosis and monitoring of gut health. This field emerged in the early 2000s with a successful translation of an endoscopic capsule from laboratory prototype to a commercially viable clinical device. Recently, this field has accelerated and expanded into various domains beyond imaging, including the measurement of gut physiological parameters such as temperature, pH, pressure and gas sensing, and the development of sampling devices for better insight into gut health. In this review, the status of smart capsules for sensing gut parameters is presented to provide a broad picture of these state-of-the-art devices while focusing on the technical and clinical challenges the devices need to overcome to realise their value in clinical settings. Smart capsules are developed to perform sensing operations throughout the length of the gut to better understand the body’s response under various conditions. Furthermore, the prospects of such sensing devices are discussed that might help readers, especially health practitioners, to adapt to this inevitable transformation in healthcare. As a compliment to gut sensing smart capsules, significant amount of effort has been put into the development of robotic capsules to collect tissue biopsy and gut microbiota samples to perform in-depth analysis after capsule retrieval which will be a game changer for gut health diagnosis, and this advancement is also covered in this review. The expansion of smart capsules to robotic capsules for gut microbiota collection has opened new avenues for research with a great promise to revolutionise human health diagnosis, monitoring and intervention.
UHTP: A User-Aware Hierarchical Task Planning Framework for Communication-Free, Mutually-Adaptive Human-Robot Collaboration

Collaborative human-robot task execution approaches require mutual adaptation, allowing both the human and robot partners to take active roles in action selection and role assignment to achieve a single shared goal. Prior works have utilized a leader-follower paradigm in which either agent must follow the actions specified by the other agent. We introduce the User-aware Hierarchical Task Planning (UHTP) framework, a communication-free human-robot collaborative approach for adaptive execution of multi-step tasks that moves beyond the leader-follower paradigm. Specifically, our approach enables the robot to observe the human, perform actions that support the human’s decisions, and actively select actions that maximize the expected efficiency of the collaborative task. In turn, the human chooses actions based on their observation of the task and the robot, without being dictated by a scheduler or the robot. We evaluate UHTP both in simulation and in a human subjects experiment of a collaborative drill assembly task. Our results show that UHTP achieves more efficient task plans and shorter task completion times than non-adaptive baselines across a wide range of human behaviors, that interacting with a UHTP-controlled robot reduces the human’s cognitive workload, and that humans prefer to work with our adaptive robot over a fixed-policy alternative.
A References Architecture for Human Cyber Physical Systems - PART II: Fundamental Design Principles for Human-CPS Interaction

As automation increases qualitatively and quantitatively in safety-critical human cyber-physical systems, it is becoming more and more challenging to increase the probability or ensure that human operators still perceive key artefacts and comprehend their roles in the system. In the companion paper, we proposed an abstract reference architecture capable of expressing all classes of system-level interactions in human cyber-physical systems. Here we demonstrate how this reference architecture supports the analysis of levels of communication between agents and helps to identify the potential for misunderstandings and misconceptions. We then develop a metamodel for safe human machine interaction. Therefore, we ask what type of information exchange must be supported on what level so that humans and systems can cooperate as a team, what is the criticality of exchanged information, what are timing requirements for such interactions, and how can we communicate highly critical information in a limited time frame in spite of the many sources of a distorted perception. We highlight shared stumbling blocks and illustrate shared design principles, which rest on established ontologies specific to particular application classes. In order to overcome the partial opacity of internal states of agents, we anticipate a key role of virtual twins of both human and technical cooperation partners for designing a suitable communication.
The role of breeding in reducing sheep GHG intensity

Historic and potential future greenhouse gas (GHG) emission reductions resulting from genetic selection decisions in sheep have been quantified. Historic genetic trends in number of lambs born in maternal breeds and growth in terminal sire breeds were estimated to have reduced GHG emissions per kilogram of lamb carcass weight by 0.45% and 0.09% per year of genetic change, respectively. The implications of future selection using different indexes were also examined. Selection based solely on farm profits could lead to emission reductions per unit of product by 0.185 kg CO2-e/kg carcass weight, or a 0.59% reduction in lamb carcass weight emissions per annum. Selection of sheep ignoring profit and solely targeting reduced GHG emissions per kilogram of lamb carcass weight could lead to emission reductions of 0.242 kg CO2-e/kg lamb carcass weight, equivalent to a 0.77% reduction in total emissions per annum. However, doing this would come at a cost of 26.6 cents per breeding ewe reduction of 23.7% per annum in annual genetic progress. An alternative index that provides a balance between reducing GHG emissions and improving farm profits was estimated to produce an annual 0.193 kg CO2-e/kg carcass weight or a reduction of 0.62% reduction in emissions per annum in GHG emissions with minimal sacrifice in genetic improvement of farm profitability.
Moments of Surprise: Preparing Technology-Oriented Students for Interdisciplinary Work

The design and development of interactive software systems requires specialized expertise and interdisciplinary collaboration. This paper presents an autoethnographic case study that seeks to explore the potential of teaching human-computer interaction to technology-oriented students for preparing them for interdisciplinary work. Selected teaching and learning activities are described where graduate students applied HCI design methods to their own practices in higher education and to everyday life. It is argued that such ‘self-confrontation’ provides opportunities for surprise and explanation seeking. Students critically reflect on their design assumptions and approaches and learn to appreciate unfamiliar design perspectives. My argument is supported by the analysis of situations that lead to surprise in the example activities. The suggested approach helps to implement dialogic teaching and learning and allows both students and teachers to develop and learn.
Kick the Tin

When Doris Kartinyeri was a month old her mother died. Her family gathered to mourn their loss, and welcome the new baby home. But Doris never returned to her family -- she was stolen from the hospital and placed in the Colebrook Home, where she stayed for the next fourteen years. This powerful memoir describes her life, and the pain of her family as they sought to have her returned to them.
A proposed function for the red body of Nannochloropsis in the formation of the recalcitrant cell wall polymer, algaenan

Stramenopile algae contribute significantly to global primary productivity, and one class, Eustigmatophyceae, is increasingly studied for applications in high-value lipid production. Yet much about their basic biology remains unknown, including the nature of an enigmatic, pigmented globule found in vegetative cells. Here, we present an in-depth examination of this “red body”, focusing on Nannochloropsis oceanica. During the cell cycle, the red body formed adjacent to the plastid, but unexpectedly it was secreted and released with the autosporangial wall following cell division. Shed red bodies contained antioxidant ketocarotenoids, and overexpression of a beta-carotene ketolase resulted in enlarged red bodies. Infrared spectroscopy indicated long-chain, aliphatic lipids in shed red bodies and cell walls, and LC-HRMS detected a C32 alkyl diol, a potential precursor of algaenan, a recalcitrant cell wall polymer. We propose that the red body transports algaenan precursors from plastid to apoplast to be incorporated into daughter cell walls.
A novel MARV glycoprotein-specific antibody with potentials of broad-spectrum neutralization to filovirus

Marburg virus (MARV) is one of the filovirus species that cause deadly hemorrhagic fever in humans, with mortality rates up to 90%. Neutralizing antibodies represent ideal candidates to prevent or treat virus disease. However, no antibody has been approved for MARV treatment to date. In this study, we identified a novel human antibody named AF-03 that targeted MARV glycoprotein (GP). AF-03 possessed a high binding affinity to MARV GP and showed neutralizing and protective activities against the pseudotyped MARV in vitro and in vivo. Epitope identification, including molecular docking and experiment-based analysis of mutated species, revealed that AF-03 recognized the Niemann-Pick C1 (NPC1) binding domain within GP1. Interestingly, we found the neutralizing activity of AF-03 to pseudotyped Ebola viruses (EBOV, SUDV, and BDBV) harboring cleaved GP instead of full-length GP. Furthermore, NPC2-fused AF-03 exhibited neutralizing activity to several filovirus species and EBOV mutants via binding to CI-MPR. In conclusion, this work demonstrates that AF-03 represents a promising therapeutic cargo for filovirus-caused disease.
Enhancement of neurophysiological signatures of working memory by combined yoga and tDCS

Transcranial direct current stimulation (tDCS) is a non-invasive neuromodulation technology that can modulate cortical excitability. Similarly, yoga has been found to influence neuronal activity and cognition. The aim of this study was to investigate the impact of combined yoga and tDCS on event-related potential (ERP) components during an N-Back working memory task. In a randomized, double-blind, cross-over design study, 22 healthy participants underwent a yoga/active tDCS session (2mA; 20min; anode on F3, cathode on F4) or a yoga/sham tDCS session on two different days. During the N-Back task, ERP components were obtained before and after each intervention. Results show that active tDCS plus yoga was associated with significant changes in the amplitude of the P200 component for the 2-Back in Fz and F3 channels and P300 for 3-Back in F3 and Pz electrodes. These results suggest that combining behavioral and electrical neuromodulation techniques may have the potential to enhance cognition and neurophysiological effects.
Evaluating the effectiveness of artifact correction and rejection in event-related potential research

Eyeblinks and other large artifacts can create two major problems in event-related potential (ERP) research, namely confounds and increased noise. Here, we developed a method for assessing the effectiveness of artifact correction and rejection methods at minimizing these two problems. We then used this method to assess a common artifact minimization approach, in which independent component analysis (ICA) is used to correct ocular artifacts, and artifact rejection is used to reject trials with extreme values resulting from other sources (e.g., movement artifacts). This approach was applied to data from five common ERP components (P3b, N400, N170, mismatch negativity, and error-related negativity). Four common scoring methods (mean amplitude, peak amplitude, peak latency, and 50% area latency) were examined for each component. We found that eyeblinks differed systematically across experimental conditions for several of the components. We also found that artifact correction was reasonably effective at minimizing these confounds, although it did not usually eliminate them completely. In addition, we found that the rejection of trials with extreme voltage values was effective at reducing noise, with the benefits of eliminating these trials outweighing the reduced number of trials available for averaging. For researchers who are analyzing similar ERP components and participant populations, this combination of artifact correction and rejection approaches should minimize artifact-related confounds and lead to improved data quality. Researchers who are analyzing other components or participant populations can use the method developed in this study to determine which artifact minimization approaches are effective in their data.