Miracle-dz/UniFAR-FTUs huggingface dataset:
Enhancing Antibiotics Efficacy by Combination of Kuraridin and Epicatechin Gallate with Antimicrobials against Methicillin-Resistant Staphylococcus aureus

Background: Staphylococcus aureus is an opportunistic pathogen and a major cause of nosocomial and community-acquired infections. The alarming rise in Methicillin-resistant S. aureus (MRSA) infection worldwide and the emergence of vancomycin-resistant MRSA strains have created an urgent need to identify new and alternative treatment options. Triple combinations of antimicrobials with different antimicrobial mechanisms may be a good choice to overcome antimicrobial resistance. Methods: In this study, we combine two natural compounds: kuraridin from Sophora flavescens and epicatechin gallate (ECG) from Camellia sinensis (Green tea), which could provide the best synergy with antibiotics against a selected panel of laboratory MRSA with known resistant mechanisms and clinical community-associated (CA) and hospital-associated (HA) MRSA as well. Results: The combined use of ECG and kuraridin was efficacious in inhibiting the growth of a panel of tested MRSA strains. The antibacterial activities of gentamicin, fusidic acid and vancomycin could be further enhanced by the addition of ECG and kuraridin. In time-kill study, when vancomycin (0.5 μg/mL) was combined with ECG (2 μg/mL) and kuraridin (2 μg/mL), a very strong bactericidal growth inhibition against 3 tested strains ATCC25923, MRSA ST30 and ST239 was observed from 2 to 24 h. ECG and kuraridin both possess anti-inflammatory activities in bacterial toxin-stimulated peripheral blood mononuclear cells by suppressing the production of inflammatory cytokines (IL-1β, IL-6 and TNFα) and are non-cytotoxic. In a murine pneumonia model infected with ATCC25923, MRSA ST30 or ST239, the combined use of ECG and kuraridin with vancomycin could significantly reduce bacterial counts. Conclusions: The present findings reveal the potential of ECG and kuraridin combination as a non-toxic herbal and antibiotics combination for MRSA treatment with antibacterial and anti-inflammatory activities.
The development and structure of turbulent plane jets

The structure and development of turbulent plane jets in still air and moving streams are described. The nature of the small-scale turbulence cannot be accurately ascertained because of the difficulties inherent in the measurement of dissipation in highly turbulent flows. Although correlation measurements in a jet in still air indicate a large-scale structure which can best be described as ‘local flapping’, measurements in a jet in a moving stream do not reveal a similar structure. The development of the turbulence structure in a jet in a moving parallel stream is described and the properties of turbulent jets and wakes are shown to be reasonably well predicted by the use of a variable-eddy-viscosity formula together with the formal self-preserving properties of the equations of motion.
Wdfy4-deficiency reveals a critical role for cross-presentation in anti-viral and anti-tumor responses

Cross-presentation allows for the presentation of exogenous viral and tumor antigens to CD8+ T cells by XCR1+ classical dendritic cells (cDC1s). Previously, the role of cross-presentation in cytotoxic T cell responses in vivo was unclear due to the lack of mouse models specifically deficient in cross-presentation. We developed a CRISPR-Cas9 screen to find novel regulators of cross-presentation and found that the protein WDFY4 is essential for cross-presentation of cell-associated antigens but not for direct presentation or presentation on MHCII. WDFY4-deficient mice had normal cDC1 development and were able to survive infections with Toxoplasma gondii through production of IL-12. However, WDFY4-deficient mice failed to prime CD8+ T cells to viral antigens and were completely unable to control immunogenic tumors. WDFY4 interacts with proteins related to vesicular formation and trafficking such as clathrin and HSP90ab1 and localizes near the cell surface, suggesting its involvement in vesicular targeting after antigen uptake during cross-presentation.
Phase Equilibria in Ternary System CsBr-AgBr-InBr3

The double perovskite halides A2BIBIIIX6 provide flexibility for various formulation adjustments and are of less toxicity in comparison with well-discussed complex lead halide derivatives. Such type of structure can be formed by replacing two Pb2+ ions in the cubic lattice with a pair of non-toxic heterovalent (monovalent and trivalent) metal cations, such as silver and indium. The aim of this work is to briefly characterize the phase equilibria in the ternary system CsBr-AgBr-InBr3 and investigate the thermodynamic availability of synthesis of Cs2AgInBr6 double perovskite phase by solid-state sintering or melt crystallization. The results demonstrate the unfeasibility of the Cs2AgInBr6 phase but high stability of the corresponding binary bromides perspective for optoelectronics.
Quasar Evolution via Galaxy Mergers

The expected evolution of quasars is calculated using the dynamics of merging galaxies and the assumption that the birth rate of quasars is proportional to the rate of mergers. The merger rate is described using a modification of the Press-Schechter theory. As a specific model, the luminosity of a quasar is assumed to be proportional to its host galaxy's halo mass, and the amount of gas supplied per merger is independent of the quasar's luminosity, implying a lifetime that is inversely proportional to luminosity. The main strength of the model is its relation to the dynamics of clustering. Its main weaknesses are the poorly constrained relations between host galaxies and quasars. 64 refs.
Harmonic analysis and pointwise ergodic theorems for noncommuting transformations

Let Fk denote the free group on k generators, 1 where S,n = {w: I = n}, and . 1 denotes the word length on Fk induced by S. Let (X, M, m) be a probability space on which Fk acts ergodically by measure preserving transformations. We prove a pointwise ergodic theorem for the sequence of operators IJ = I(a,, + a,n+,) acting on L 2(X), namely: a'f(x) -fX fdm almost everywhere, for each f in L 2(X) . We also show that the sequence a2n converges to a conditional expectation operator with re- spect to a a-algebra which is invariant under Fk . The proof is based on the spectral theory of the (commutative) convolution subalgebra of e I(Fk) gener- ated by the elements an, n > 0 . We then generalize the discussion to algebras arising as a Gelfand pair associated with the group of automorphisms G(rI, r2) of a semi-homogeneous tree T(r,, r2), where r, > 2, r2 > 2, r, + r2 > 4. This content downloaded from 207.46. 13.114 on Thu, 26 May 2016 06:27:50 UTC All use subject to http://about.jstor. org/terms
Coupling two unimodal maps with simple kneading sequences

The dynamics of a system of two diffusively coupled identical unimodal maps is investigated. The unimodal maps have simple kneading sequences which imply that their orbits are asymptotically periodic with period a power of two. Analogous results are obtained for the coupled system for all coupling parameters. We prove the eventual periodicity of the position of orbits with respect to the diagonal of the square phase space and the asymptotic periodicity for orbits whose coordinates have the same sign. Finally, we give a global condition for the existence of symmetric orbits that are examples of orbits with this asymptotic property.
Collective aspects of the dipole response in nuclei: an analysis from semi-classical and quantal approaches.

Within the framework of semiclassical and quantal approaches, we explore the dipole response properties in selected neutron-rich nuclei and in Sn isotopes. One of the goals of this analysis is to disentangle genuine collective aspects from single particles features. Focusing on the low- energy response, below the GDR region, we are able to identify one isovector-like mode and two isoscalar-like modes of considerable strength. In particular, owing to its mixed nature in neutron- rich nuclei, the lowest energy isoscalar-like mode also contributes to the isovector response and can be associated with the so-called Pygmy Dipole Resonance (PDR). We show that the isoscalar and isovector strengths of these low-energy modes evolve with nuclear global features, such as the density profile and neutron skin. In this sense, they also reflect important properties of the nuclear effective interaction. A thourough analysis of the associated transition densities turns out to be quite useful to better characterize the mixed nature of the different modes and their surface/volume components.
Cloudy Winter Satellite Temperature Retrievals over the Extratropical Northern Hemisphere Oceans

Abstract An experimental colocation and statistical regression scheme is used to verify the hypothesis that large consistent mean errors in the cloudy oceanic satellite temperature retrievals north of 30°N from TIROS-N are due to a continental bias in the statistical colocation base. Sea surface water temperature is a useful predictor for these conditions. Significant improvement in these retrievals is possible. However, much of this improvement requires the presence in the colocation base of the, mid-ocean radiosondes from the ocean weather ships.
Attack Hypotheses Generation Based on Threat Intelligence Knowledge Graph

Cyber threat intelligence on past attacks may help with attack reconstruction and the prediction of the course of an ongoing attack by providing deeper understanding of the tools and attack patterns used by attackers. Therefore, cyber security analysts employ threat intelligence, alert correlations, machine learning, and advanced visualizations in order to produce sound attack hypotheses. In this article, we present AttackDB, a multi-level threat knowledge base that combines data from multiple threat intelligence sources to associate high-level ATT&CK techniques with low-level telemetry found in behavioral malware reports. We also present the Attack Hypothesis Generator which relies on knowledge graph traversal algorithms and a variety of link prediction methods to automatically infer ATT&CK techniques from a set of observable artifacts. Results of experiments performed with 53K VirusTotal reports indicate that the proposed algorithms employed by the Attack Hypothesis Generator are able to produce accurate adversarial technique hypotheses with a mean average precision greater than 0.5 and area under the receiver operating characteristic curve of over 0.8 when it is implemented on the basis of AttackDB. The presented toolkit will help analysts to improve the accuracy of attack hypotheses and to automate the attack hypothesis generation process.
A technique for obtaining pattern symmetry and low sidelobes from a TE 11 mode coaxial radiator

The radiation characteristics of a TE_{11} mode excited semi-infinite coaxial waveguide are examined. Kirchoff-Huygen analysis illustrates a pattern sensitivity to the transverse coaxial dimension ratio which can render the TE_{11} mode coaxial radiator unattractive for many antenna applications. A circular iris at the aperture of the coaxial waveguide is shown to provide radiation pattern improvement. Transverse aperture field distributions, obtained by modal analysis methods, lead to radiation patterns characterized by beamwidth symmetry and low sidelobes. Experimental verification of the pattern characteristics of the modified coaxial radiator are demonstrated as well as favorable agreement between computed and measured data.
Performance Analysis of Scalable User-Centric HC-RAN Over Rician Fading Channels

In this paper, we analyze the uplink performance of a scalable user-centric heterogeneous cloud-radio access network (HC-RAN) implemented by using dynamic cooperative clustering (DCC) framework over a Rician fading channel with phase shifts. This channel describes various practical aspects, such as a deterministic line of sight (LoS) component and random non-LoS (N-LoS) components. To account for the phase shifts due to user mobility, the phase of the LoS component is modeled as a uniformly distributed random variable. We assume that phase information is available at each remote radio head (RRH). We derived the phase aware-minimum mean square error (PA-MMSE) and phase unaware Linear-MMSE estimators and obtained the channel state information (CSI). We derived a closed-form expression for the achievable spectral efficiency (SE) to evaluate the system performance with both estimators. To address the effect of coherent interference in the ultra-dense networks, we developed a two-layer decoding scheme in uplink in which maximum ratio (MR) combining is performed at the RRH and large-scale fading decoding is performed at the base-band unit (BBU) pool. Based on the obtained results, the proposed method enhanced the uplink performance in an ultra-dense scenario. It is validated by comparing it with the simulation results. Moreover, the performance loss caused by the lack of phase knowledge will depend on the pilot sequence length.
A comprehensive review of the ethnobotanical, phytochemical, and pharmacological properties of the genus Bambusa

Throughout Africa, China, India, and other parts of the world for ages, the genus Bambusa (Poaceae) has been utilized in folk medicine. Various studies have concentrated on the ethnobotany, phytochemistry, and pharmacology of Bambusa spp. in recent years. This scoping study employed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guideline to analyze articles published from 2003 to 2021 on Bambusa spp. The articles were also retrieved from the Scopus database. As a result, 97 articles were selected based on the criteria given: 50 articles for the ethnobotanical aspect, 11 articles for the phytochemical aspect, and 44 articles for the pharmacological aspects (including 8 similar articles from other aspects). A large variety of pharmacological activities, including antioxidant, anti-inflammatory, antibacterial, antifungal, antimalarial, anticancer, antidiabetic, abortifacient, and cytotoxicity activities, were found in the crude extracts and purified bioactive components of Bambusa spp. Alkaloids, flavonoids, phenolics, terpenoids, and other compounds have all been isolated and named from Bambusa spp. Bambusa spp. have a sizable worldwide marketplace due to their outstanding medicinal benefits and minimal toxicity, which has sparked increased attention from academics. Nevertheless, there is no available review article that has compiled all the information regarding the utilization and properties of Bambusa spp. Hence, this review aims to identify and reveal the widely used Bambusa spp. that have grown worldwide. The review mainly summarizes the phytoconstituents and their corresponding pharmacological properties, which are significant in providing a collective scientific evaluation of Bambusa spp. for the development and utilization of a potential novel ethnomedicine.
On George’s Nested Dissection Method

We make a precise recommendation for the choice of dissection sets for George’s [4] nested dissection on a square $n \times n$ grid with n not a power of 2 and make some experimental comparisons with the direct use of the minimal degree algorithm of Markowitz [5]. Our results additionally indicate that the performance of the minimal degree algorithm can be significantly influenced by the way in which ties are broken. We also discuss the dissection of irregularly shaped regions and the extension of George’s ordering to three-dimensional regions.
Acoustic Ambient Noise in the Ocean: Spectra and Sources

The results of recent ambient‐noise investigations, after appropriate processing, are compared on the basis of pressure spectra in the frequency band 1 cps to 20 kc. Several possible sources are discussed to determine the most probable origin of the observed noise. It is concluded that, in general, the ambient noise is a composite of at least three overlapping components: turbulent‐pressure fluctuations effective in the band 1 cps to 100 cps; wind‐dependent noise from bubbles and spray resulting, primarily, from surface agitation, 50 cps to 20 kc; and, in many areas, oceanic traffic, 10 cps to 1000 cps. Spectrum characteristics of each component and of the composite are shown. Additional sources, including those of intermittent and local effects, are also discussed. Guidelines for the estimation of noise levels are given.
Increase in photoluminescence intensity of InAs columnar quantum dots on InP(001) substrate by increasing indium and phosphorous composition in InGaAsP barrier layers

We investigated the effect of the alloy composition of InGaAsP barrier layers on the photoluminescence (PL) properties of InAs columnar quantum dots (CQDs) grown by metal organic vapor phase epitaxy (MOVPE). The PL wavelength of the CQDs was controlled by the strain of the InGaAsP barrier layers for fixed bandgap wavelength conditions. The PL intensity of the CQDs showed significant increase with the bandgap energy of the barrier layers, that is, with increasing indium and phosphorus composition, due to the reduced defects and dislocation in the samples. The result is considered to be related to the miscibility of the InGaAsP quaternary alloy at a low growth temperature. By applying a larger bandgap energy to the barrier layers, triple-stacked CQDs with high crystalline quality was demonstrated in the 1.55-μm region.
The secondary stars in cataclysmic variables and low-mass X-ray binaries

We critically re-examine the available data on the spectral types, masses and radii of the secondary stars in cataclysmic variables (CVs) and low-mass X-ray binaries (LMXBs), using the new catalogue of Ritter & Kolb as a starting point. We find there are 55 reliable spectral type determinations and only 14 reliable mass determinations of CV secondary stars (10 and 5, respectively, in the case of LMXBs). We derive new spectral type–period, mass–radius, mass–period and radius–period relations, and compare them with theoretical predictions. We find that CV secondary stars with orbital periods shorter than 7–8 h are, as a group, indistinguishable from main-sequence stars in detached binaries. We find that it is not valid, however, to estimate the mass from the spectral type of the secondary star in CVs or LMXBs. We find that LMXB secondary stars show some evidence for evolution, with secondary stars which are slightly too large for their mass. We show how the masses and radii of the secondary stars in CVs can be used to test the validity of the disrupted magnetic braking model of CV evolution, but we find that the currently available data are not sufficiently accurate or numerous to allow such an analysis. As well as considering secondary star masses, we also discuss the masses of the white dwarfs in CVs, and find mean values of M1 ¼ 0:69 6 0:13 M ⊙ below the period gap, and M1 ¼ 0:806 0:22 M⊙ above the period gap.
Global convergence of the log-concave MLE when the true distribution is geometric

Let X1, …, Xn be i.i. d. from a discrete probability mass function (pmf) p. In Balabdaoui et al. [(2013), ‘Asymptotic Distribution of the Discrete Log-Concave mle and Some Applications’, JRSS-B, in press], the pointwise limit distribution of the log-concave maximum-likelihood estimator (MLE) was derived in both the well- and misspecified settings. In the well-specified setting, the geometric distribution was excluded, classified as being degenerate. In this article, we establish the global asymptotic theory of the log-concave MLE of a geometric pmf in all ℓq distances for q∈{1, 2, …}∪{∞}. We also show how these asymptotic results could be used in testing whether a pmf is geometric.
Spectral hole‐burning and gain saturation in semiconductor lasers: Strong‐signal theory

The nonlinear susceptibility of semiconductor gain media is obtained by including the effect of intraband carrier relaxation within the density‐matrix formalism. The result is used to obtain the approximate analytic expressions showing how the optical gain and the refractive index change with an increase in the laser power. The index change is generally small but can be positive or negative depending on which side of the gain peak the lasing mode is located. By contrast, the gain is always reduced because of spectral hole‐burning. The implications of gain saturation on the dynamic response of semiconductor lasers are discussed together with the possibility of experimental verification.
Study on radial uniformity of large aperture capacitively coupled plasma

We simulated a large-aperture capacitively coupled plasma (CCP) using a two-dimensional fluid model, and explored the effects of radio frequency, electrode power, and gas pressure on the period-averaged electron density and electron temperature. The influence and control ability of various discharge parameters on the plasma uniformity are analyzed, which provides reference for the selection of plasma process parameters.
Classifying Paintings into Movements using HOG and LBP Features

With the increase in availability of paintings on the web, the importance of organizing art collections cannot be overstated. By classifying paintings based on art movements, information about paintings on the web can be well structured. This will also help us garner insights into more obscure paintings and the styles they embody. This paper discusses a method of classifying paintings into two art movements, namely Cubism and Romanticism, using two texture descriptors: Local Binary Pattern (LBP) and Histogram of Oriented Gradients (HOG). The paper also extends the applicability of the method to different classifiers. Some classifiers used for classification are KNN, NuSVC, LinearSVC, GaussNB, Decision Tree, Random Forest, AdaBoost and Gradient Boost. A subset of the Pandora database is used as a dataset. From the results, it can be inferred that using the Gradient Boost classifier gives the highest overall accuracy for Cubism and Romanticism when LBP and HOG are used as texture descriptors. Moreover, it can be seen that LBP emerges as the best feature for classifying paintings into the Cubism and Romanticism Art Movements.
Influence of Sex and Muscarinic Activity on Memory Retrieval in Mouse Model of Traumatic Brain Injury

Traumatic brain injury (TBI) is a serious global risk factor leading to the onset of cognitive impairment and neurodegenerative diseases. Cognitive and memory impairment following a TBI is associated with the dysregulation of cholinergic neurotransmission in the brains of subjects. The extent of memory impairment following a TBI is linked with the sex of the subject. This study aimed to identify the sex-dimorphic role of muscarinic cholinergic modulation in neurological functioning and episodic memory retrieval in a mouse model of TBI. Balb/c mice were divided into four groups of males and four groups of females (i.e., Sham, TBI, TBI + Scopolamine 1 mg/kg, and TBI + Donepezil 1 mg/kg). After training with the Morris water maze test and fear conditioning, all groups were subjected to brain injury (7.84 × 10−5 J impact force) except for the Sham mice. Following brain injury, scopolamine or donepezil was administered to the respective groups for 5 days. Acute scopolamine immediately after brain trauma showed a neuroprotective effect in the males only, while subchronic donepezil significantly impaired neurological functioning in both sexes. Subchronic scopolamine and donepezil treatment reversed the TBI-induced retrograde amnesia for spatial memory in male mice. Contextual fear memory retrieval was not affected by the TBI and treatments in both sexes. Thus, we concluded that the sex-dimorphic response of the muscarinic receptors in TBI-induced memory impairment depends on the type of memory. This study highlights the potential for therapeutic modalities in TBI subjects.