Miracle-dz/UniFAR-FTUs huggingface dataset:
Intensificación de Ustekinumab en enfermedad de Crohn: Revisión sistemática

Introducción: Ustekinumab surge como una alternativa terapéutica en enfermedad de Crohn en pacientes con fracaso a anti-TNF. Sin embargo, en muchas ocasiones, es habitual tener que reducir/acortar sus tiempos de administración para evitar el fracaso terapéutico. El objetivo de esta revisión sistemática es evaluar la efectividad de la intensificación de ustekinumab mediante el acortamiento de su intervalo terapéutico. Método: Se realizó una revisión sistemática de la literatura basada en las directrices de la declaración PRISMA. Se consultaron las bases de datos Medline, Embase y Web of Science, incluyéndose estudios con adultos diagnosticados de enfermedad de Crohn moderada o grave a los que se le hubiera realizado como intervención un cambio de posología del fármaco ustekinumab mediante acortamiento de intervalo a cada 4 semanas. Resultados: Se incluyeron 5 artículos, siendo uno de ellos una revisión sistemática. A los 6 meses se muestran tasas de remisión clínica en torno al 45%, una reducción media de 3 puntos en el índice de Harvey Bradshaw sobre el nivel basal, así como una normalización de niveles de PCR en un 21% de los pacientes. Conclusiones: Los resultados apoyan el uso del acortamiento de intervalo de ustekinumab como una opción terapéutica efectiva y útil para pacientes con pérdida de respuesta a la pauta habitual. Sin embargo, se recomienda realizar nuevos estudios de diseño experimental que aumenten el nivel de evidencia existente.
The demographics of neutron star – white dwarf mergers

Context. The mergers of neutron stars (NSs) and white dwarfs (WDs) could give rise to explosive transients, potentially observable with current and future transient surveys. However, the expected properties and distribution of such events is not well understood. Aims. Here we characterise the rates of such events, their delay-time distributions, their progenitors, and the distribution of their properties. Methods. We use binary population synthesis models and consider a wide range of initial conditions and physical processes. In particular we consider different common-envelope evolution models and different NS natal kick distributions. We provide detailed predictions arising from each of the models considered. Results. We find that the majority of NS–WD mergers are born in systems in which mass-transfer played an important role, and the WD formed before the NS. For the majority of the mergers the WDs have a carbon-oxygen composition (60−80%) and most of the rest are with oxygen-neon WDs. The time-integrated rates of NS–WD mergers are in the range of 3−15% of the type Ia supernovae (SNe) rate. Their delay-time distribution is very similar to that of type Ia SNe, but is slightly biased towards earlier times. They typically explode in young 100 Myr < τ < 1 Gyr environments, but have a tail distribution extending to long, gigayear-timescales. Models including significant kicks give rise to relatively wide offset distribution extending to hundreds of kiloparsecs. Conclusions. The demographic and physical properties of NS–WD mergers suggest they are likely to be peculiar type Ic-like SNe, mostly exploding in late-type galaxies. Their overall properties could be related to a class of recently observed rapidly evolving SNe, while they are less likely to be related to the class of Ca-rich SNe.
Clinical Efficacy of Pretransplant Vaccination for Preventing Herpes Zoster After Living Donor Liver Transplantation in Recipients Age 50 Years and Older

Background There have been no reports concerning the efficacy of pretransplant herpes zoster (HZ) vaccination following living donor liver transplantation (LDLT). Material/Methods From January 2013 to May 2016, 24 patients age 50 years and older received vaccination of HZ prior to transplantation and underwent LDLT at a single institution. We compared this to the 1-year HZ incidence of unvaccinated recipients (N=180) who underwent LDLT in the same time period. Results For general characteristics, the MELD scores (p<0.001) and CTP grades (p=0.007) of the vaccinated group were significantly lower than those of the unvaccinated group. In Kaplan-Meier analysis, the 1-year HZ incidence rates of the vaccinated and unvaccinated groups were 2 (8.7%) and 16 (9.9%) cases, respectively (p=0.883). In the subgroup aged 50–59 years, 2 vaccinated recipients had HZ after LDLT. However, in the subgroup aged 60 years and older, no vaccinated recipients had HZ after LDLT. Multivariate analysis showed the independent risk factor for HZ after LDLT was use of mycophenolate mofetil (MMF; hazard ratio [HR]=3.00; p=0.041). Conclusions The efficacy of pretransplant vaccination for preventing HZ was not apparent in our study. A large prospective study is needed to determine the indications for pretransplant HZ vaccination according to age group and to evaluate the efficacy of HZ vaccination after LDLT.
The efficiency of photodissociation for molecules in interstellar ices

Processing by interstellar photons affects the composition of the icy mantles on interstellar grains. The rate of photodissociation in solids differs from that of molecules in the gas phase. The aim of this work was to determine an average, general ratio between photodissociation coefficients for molecules in ice and gas. A 1D astrochemical model was utilized to simulate the chemical composition for a line of sight through a collapsing interstellar cloud core, whose interstellar extinction changes with time. At different extinctions, the calculated column densities of icy carbon oxides and ammonia (relative to water ice) were compared to observations. The latter were taken from literature data of background stars sampling ices in molecular clouds. The best-fit value for the solid/gas photodissociation coefficient ratio was found to be ~0.3. In other words, gas-phase photodissociation rate coefficients have to be reduced by a factor of 0.3 before applying them to icy species. A crucial part of the model is a proper inclusion of cosmic-ray induced desorption. Observations sampling gas with total extinctions in excess of ~22 mag were found to be uncorrelated to modelling results, possibly because of grains being covered with non-polar molecules.
The LTE solar abundance of neodymium

We study the solar photospheric abundance of singly ionized neodymium (Nd II) using high resolution spectroscopic data obtained by Fourier transform spectrograph (FTS). Based on the Local Thermodynamical Equilibrium (LTE) assumption, a new value of Nd abundance is derived. We succeed to select of 51 solar Nd II lines with accurate transition probabilities measured experimentally by Den Hartog et al. (2003) and with accurate damping parameters are determined from literature. Relying on atomic data of Opacity Distribution Function (ODF), we construct theoretical photospheric solar model. The mean solar photospheric abundance obtained from all 51 Nd II lines is log {\epsilon}Nd=1.45 +- 0.08, which is mostly similar to the meteoric value.
Hydrodynamic behavior of non-interacting quantum particles in presence of dephasing

In solids and organic materials, environment-induced dephasing of particles and long-lived excitations leads to the crossover in their transport properties between quantum wave-like propagation and classical diffusive motion. In this work, we demonstrate that dynamics of single carriers in this intermediate crossover regime can exhibit distinct signatures such as the formation of vortices and viscous flow, the phenomena typically considered as manifestations of hydrodynamic transport. We explain this effect by modeling suppressed quantum interference of carriers, and we show that the resulting dynamics resembles the linearized Navier-Stokes equations. Dephasing-assisted viscosity provides a potential alternative explanation of the results of recent experiments exhibiting hydrodynamic behavior in solids, and suggests experimental probes of how quantum carriers couple to their environment.
Impact of foreign direct investment on socio-economic development in belt and road countries

Abstract This study is an attempt to empirically investigate the impact of foreign direct investment (FDI) on socio-economic development in the “Belt & Road” initiative (BRI) countries. It employed panel data for the period 2005 to 2018. This study used three socio-economic development indicators, life expectancy, GNI per capita, and human capital development, as outcome variables. This study found a long-run association between FDI and socio-economic development. The baseline regression results indicate that FDI does not contribute to socio-economic development in BRI countries and these findings are robust with Fully Modified Ordinary Least Square (FMOLS). However, when taking into account the region-wise analysis it is found that FDI has a positive and significant impact on poverty reduction in South Asia (SA) and Central and Western Asia (CWA) region and a negative impact in Central and East Europe (CEU) and Middle East North Africa (MENA) and it has no effect on poverty reduction in Sub-Sahara Africa (SSA) and East Asia Pacific (EAP) region. FDI has a positive effect on improved health facilities in SA and CWA region and it has a statistically insignificant or negative impact in the rest of the region. Finally, there is a positive and significant impact of FDI on human capital development in CEU and EAP region and negative association in MENA, however, it has no role in SA, CWA and SSA region. This finding postulates an idea that foreign direct investment is not a black and white mechanism. It is recommended that governments of BRI countries must prioritize public health facilities, social safety programs, poverty reduction initiatives, and human capital development strategies when looking for foreign direct investment in the country.
Elasticity and response in nearly isostatic periodic lattices

Elasticity and response in nearly isostatic periodic lattices The emergence of rigidity, especially when complicated by disorder, is a subtle phenomenon that occurs in a wide variety of systems. Isostatic lattices, such as the d-dimensional hypercubic lattice and the 2d kagome lattice with nearest neighbor springs, in which the number of contacts z per particle in d-dimensions is equal to z c = 2d, provide simple models, which inform us about systems like jammed solids, glasses, colloidal suspensions, and foams, for the analytic study of general features of the onset of rigidity. Isostatic lattices are marginally stable and may exhibit a non-extensive number of zero modes that can be removed by the addition of bond-bending forces, negative pressure, or additional springs. We use the coherent potential approximation (CPA) to study the onset of rigidity induced by randomly adding next-nearest-neighbor (N N N) bonds to the square and kagome lattices, and we relate the results to the random packings of frictionless spheres at point J. We identify a characteristic frequency scale ω * and length scale l * and show that within the CPA they scale, respectively, as ∆z and ∆z −1 where ∆z = z −z c. This result, which replicates results near jamming, is a result of strongly nonaffine elastic response at small ∆z. We find that the frequency-dependent effective N N N spring constant κ obeys a scaling relation κ(ω)/κ(0) = f (ω/ω *), where κ(0) ∼ (∆z) 2. In the square lattice the shear modulus G(ω) is equal to κ(ω), whereas in the kagome lattice, the shear modulus G 0 at ∆z = 0 is finite and proportional to the spring constant of nearest-neighbor bonds, and G(ω) − G 0 ∼ κ(ω), Finally, we show that the CPA exhibits strong phonon scattering for ω > ω * indicating a Ioffe-Regel limit for heat transport.
Towards a systematic analysis of fuzzy observers

The paper deals with the analysis of local fuzzy observers for nonlinear plants. The plant is approximated by a TS fuzzy model for which a local linear fuzzy observer is designed. This type of fuzzy observer reconstructs the non-measurable states if the parameters of the locally linearized plant are given. Matched uncertainties in the plant model can be eliminated by an additional nonlinear fuzzy sliding mode observer. Conditions are given under which the combination of the linear and the nonlinear observer lead to a reconstruction of non-measurable states.
The symmetry of inner elastic constants

The symmetry of inner elastic constants depends on the symmetry of the fundamental interlattice tensors from which they are built up. The number of independent interlattice tensors and their symmetries are determined by considering transformations of the interlattice index using a representation of the space group in which the not-purely-translational elements correspond to permutations. The method is explained and illustrated in detail. The non-zero components of the interlattice tensors are determined by standard methods and results are tabulated for the six species of tensor under consideration.
Reduction of traps and improvement of carrier lifetime in 4H-SiC epilayers by ion implantation

The authors report a significant reduction in deep level defects and improvement of carrier lifetime in 4H-SiC material after carrying out carbon or silicon ion implantation into the shallow surface layer of 250nm and subsequent annealing at 1600°C or higher temperature. Reduction of Z1∕2 and EH6∕7 traps from 3×1013cm−3 to below the detection limit (5×1011cm−3) was observed by deep level transient spectroscopy in the material 4μm underneath the implanted layer. Minority carrier lifetime almost doubled in the implanted samples compared to the unimplanted samples. The authors propose that the implanted layer acts as a source of carbon interstitials which indiffuse during annealing and accelerate annealing out of grown-in defects in the layer underneath the implanted region.
Kelvin-Helmholtz instabilities in tokamak edge plasmas

The parallel Kelvin–Helmholtz instability is investigated as a possible explanation for poloidal asymmetries of density fluctuations which reverse with the plasma current direction. It is shown that these modes are localized around the position where the radial gradient of parallel velocity is maximum. Two mechanisms lead to unstable Kelvin–Helmholtz modes; the acceleration of ions in a presheath and the anomalous Stringer spin-up due to asymmetries of the particle flux. Up–down asymmetries are explained by combining these two effects. Depending on the limiter configuration, the Stringer effect amplifies or weakens the flow due to presheath acceleration. This type of asymmetry reverses with the plasma current direction.
Matrix product states algorithms and continuous systems

A generic method to investigate many-body continuous-variable systems is pedagogically presented. It is based on the notion of matrix product states (so-called MPS's) and the algorithms thereof. The method is quite versatile and can be applied to a wide variety of situations. As a first test, we show how it provides reliable results in the computation of fundamental properties of a chain of quantum harmonic oscillators achieving off-critical and critical relative errors of the order of 10(-8) and 10(-4), respectively. Next, we use it to study the ground-state properties of the quantum rotor model in one spatial dimension, a model that can be mapped to the Mott insulator limit of the one-dimensional Bose-Hubbard model. At the quantum critical point, the central charge associated with the underlying conformal field theory can be computed with good accuracy by measuring the finite-size corrections of the ground-state energy. Examples of MPS computations both in the finite-size regime and in the thermodynamic limit are given. The precision of our results is found to be comparable to that previously encountered in the MPS studies of, for instance, quantum spin chains. Finally, we present a spin-off application: an iterative technique to efficiently get numerical solutions of partial differential equations of many variables. We illustrate this technique by solving Poisson-like equations with precisions of the order of 10(-7).
Early, emotional and embodied? Processing of emotional words and body words in the native and a second language – evidence from early event-related brain potential modulation and rapid serial visual presentation

ABSTRACT Visual processing of emotional words modulates early event-related potentials (ERPs) such as the early posterior negativity (EPN). Questions remain as to whether this modulation reflects modality-specific processing, preferentially elicited by emotional words of the native language (L1). This study investigates the modulation of early ERPs during rapid serial visual presentation (RSVP) of adjectives or nouns referring to emotional feeling states, neutral traits, to an overweight or lean body or to concrete body parts or neutral objects, presented in the L1 and the second language (L2). Word ratings in the L2 were assessed in a pilot study. The N100 and the EPN were modulated by the emotional valence of the stimuli irrespective of the word class or the task (silent reading vs. word counting). The results suggest that early affective appraisal is obligatory, not restricted to privileged categories of linguistic information (emotions) or solely found for the embodied language (L1).
Cluster Structure of Online Users Generated from Interaction Between Fake News and Corrections

SUMMARY The problem caused by fake news continues to worsen in today’s online social networks. Intuitively, it seems eﬀective to issue corrections as a countermeasure. However, corrections can, ironically, strengthen attention to fake news, which worsens the situation. This paper proposes a model for describing the interaction between fake news and the corrections as a reaction-diﬀusion system; this yields the mechanism by which corrections increase attention to fake news. In this model, the emergence of groups of users who believe in fake news is understood as a Turing pattern that appears in the activator-inhibitor model. Numerical calculations show that even if the network structure has no spatial bias, the interaction between fake news and the corrections creates groups that are strongly interested in discussing fake news. Also, we propose and evaluate a basic strategy to counter fake news.
Controlling mechanism for dual-label transport in T-MPLS

T-MPLS is a connection-oriented packet switched solution for transport networks. The standardization process is pushed by ITU-T and IETF, many recommendation appeared in these days. T-MPLS is much easier to achieve a convergent packet platform for any L2 protocol. It focuses on the packet transport application that adhere to the standard groups. Although IETF PWE3 WG have already specified the common architecture for L2/L3 service encapsulation, as different service always has different characteristics. So we propose a control mechanism for dual label transport across T-MPLS in this paper, through which we can easily achieve a convergent packet transporting platform for any L2 and L3 protocols, . At last, a flow chart for T-MPLS realization and a FSM structure have been introduced.
Polyaniline/ZnO composites prepraped via a green route for sunlight-driven photocatalytic efficient decolorization of methyl orange dye

Hybrid composites formed by semi-conductor metal oxide (ZnO) and conducting polymer (PANI) were prepared by simple, efficient, low-cost and environmentally-friendly methods, namely mech-ano-chemical reaction and a solution combustion synthesis. X-ray diffraction, scanning electron microscopy, Fourier-transform infrared spectroscopy, UV-Visible, laser granulometry, Raman and photoluminescence (PL) spectroscopies were carried out to study the effect of both the grinding time and weight percent ratio of ZnO:PANI on the structure and morphology of ZnO/PANI composites. The X-ray diffraction results show that solution combustion synthesis gave a wurtzite hexagonal structure of pure ZnO and ZnO/x wt. % PANI composites contained zinc oxide with a semi-crystalline phase of polyaniline. Experimental findings demonstrate that the decrease of the grain size particles from 42.15 to 24.49 μm, for ZnO/60 wt. % PANI and the grinding time increase were accompanied by the reduction of PL intensity and electron-hole recombination. The effect of the percentage of polyaniline in the composites on the photodegradation reaction of methyl orange (MO) was also investigated. UV-Vis spectrophotometer findings reveal the adsorption of UV irradiation by all composites and, hence, the decomposition of MO. ZnO/60 wt. % PANI showed good photocatalytic behaviour towards MO dye with a decoloration percentage of 90% after being exposed to sunlight irradiation during 1 h. This rate is six times higher than ZnO in the same conditions. It was obvious that the prolongation of the charge-carrier recombination time, resulting from sensitizing by polymer and activation by grinding, improved the efficiency of the studied composites towards the photocatalytic degradation of MO.
RESONANT ACTIVATION DRIVEN BY STRONGLY NON-GAUSSIAN NOISES

The constructive role of non-Gaussian random fluctuations is studied in the context of the passage over the dichotomously switching potential barrier. Our attention focuses on the interplay of the effects of independent sources of fluctuations: an additive stable noise representing non-equilibrium external random force acting on the system and a fluctuating barrier. In particular, the influence of the structure of stable noises on the mean escape time and on the phenomenon of resonant activation (RA) is investigated. By use of the numerical Monte Carlo method it is documented that the suitable choice of the barrier switching rate and random external fields may produce resonant phenomenon leading to the enhancement of the kinetics and the shortest, most efficient reaction time.
Penerapan Akuntansi pada Usaha Mikro Kecil dan Menengah (Studi pada UMKM Kerupuk Kulit Tradisional Kelurahan Seganteng)

This study aims to determine the application of accounting for MSMEs and the constraints faced in the making of financial report for “UMKM Kerupuk Kulit Tradisional” in the Seganteng village. The research uses descriptive method in the form of a survey. The data was obtained through the administration of questionnaires to MSMEs in the Seganteng village, and processed using frequency distribution. The results showed that the majority (68%) of its entrepreneurs had not prepared financial reports due to limited understanding and ability of accounting and bookkeeping. The complexity of the accounting process and the majority of MSME actors considered that financial statements were not an important thing to do. While the remaining 32% only make a simple cash flow reports (cash inflow and outflow). On average, however, MSMEs in Seganteng have implemented accounting practices as 86% have prepared a report on sales and purchases, while only 45% have prepared a report on cash flow.