Miracle-dz/UniFAR-FTUs huggingface dataset:
The GenoDiabMar Registry: A Collaborative Research Platform of Type 2 Diabetes Patients

The GenoDiabMar registry is a prospective study that aims to provide data on demographic, biochemical, and clinical changes in type 2 diabetic (T2D) patients attending real medical outpatient consultations. This registry is also used to find new biomarkers related to the micro- and macrovascular complications of T2D, with a particular focus on diabetic nephropathy. With this purpose, longitudinal serum and urine samples, DNA banking, and data on 227 metabolomics profiles, 77 immunoglobulin G glycomics traits, and other emerging biomarkers were recorded in this cohort. In this study, we show a detailed longitudinal description of the clinical and analytical parameters of this registry, with a special focus on the progress of renal function and cardiovascular events. The main objective is to analyze whether there are differential risk factors for renal function deterioration between sexes, as well as to analyze cardiovascular events and mortality in this population. In total, 650 patients with a median age of 69 (14) with different grades of chronic kidney disease—G1–G2 (eGFR > 90–60 mL/min/1.73 m2) 50.3%, G3 (eGFR; 59–30 mL/min/1.73 m2) 31.4%, G4 (eGFR; 29–15 mL/min/1.73 m2) 10.8%, and G5 (eGFR < 15 mL/min/1.73 m2) 7.5%—were followed up for 4.7 (0.65) years. Regardless of albuminuria, women lost 0.93 (0.40–1.46) fewer glomerular filtration units per year than men. A total of 17% of the participants experienced rapid deterioration of renal function, 75.2% of whom were men, with differential risk factors between sexes—severe macroalbuminuria > 300 mg/g for men OR [IQ] 2.40 [1.29:4.44] and concomitant peripheral vascular disease 3.32 [1.10:9.57] for women. Overall mortality of 23% was detected (38% of which was due to cardiovascular etiology). We showed that kidney function declined faster in men, with different risk factors compared to women. Patients with T2D and kidney involvement have very high mortality and an important cardiovascular burden. This cohort is proposed as a great tool for scientific collaboration for studies, whether they are focused on T2D, or whether they are interested in comparing differential markers between diabetic and non-diabetic populations.
Modelling The Human Upper BodyIn Three-dimensional Motion

A six-link model representing the human upper body and arm was developed. A set of joint restraints based on the ergonomic ranges of joint angles has been applied to allow the synthesis of upper body motion. Using anthropometric information for scaling subject size and mass parameters, an inverse dynamic model of arms and the thorax is employed to determine the necessary joint moments for the desired trajectory and speed of the hand. Acceleration profiles along the proposed trajectory allow the full synthesis of a motion for a human performing a simple pick-and-place task. Three-dimensional data was gathered for a human subject performing the same task. The trajectory naturally used by the human subject and the trajectory hypothesized for the synthesis is compared and differences are analyzed. Changes in trajectory used by the human subject as a result of changes in workstation geometry were analyzed. The joint moments resulting from the trajectory used by the human subject were compared to those generated by the computer synthesis using the linkage model. Joint moments required by the human were found to be less smooth than those of the synthesis and to have peak values significantly larger than those of the synthesis.
Radio Propagation and Adaptive Antennas for Wireless Communication Networks

Explores novel wireless networks beyond 3G, and advanced 4G technologies, such as MIMO, via propagation phenomena and the fundamentals of adapted antenna usage.Explains how adaptive antennas can improve GoS and QoS for any wireless channel, with specific examples and applications in land, aircraft and satellite communications.Introduces new stochastic approach based on several multi-parametric models describing various terrestrial scenarios, which have been experimentally verified in different environmental conditionsNew chapters on fundamentals of wireless networks, cellular and non-cellular, multiple access networks, new applications of adaptive antennas for positioning, and localization of subscribersIncludes the addition of problem sets at the end of chapters describing fundamental aspects of wireless communication and antennas.
Confidence interval of the parameter on multipredictor biresponse longitudinal data analysis using local linear estimator for modeling of case increase and case fatality rates COVID-19 in Indonesia: A theoretical discussion

In this paper, we describe a theoretical discussion about confidence intervals for longitudinal data based on local linear estimator. The confidence interval represents the range of possible values in the estimating process. The confidence intervals for the parameter in nonparametric regression can be used to determine the predictor variables that have a significant effect on the response variable. In this research, we theoretically discuss estimation of the confidence interval of the parameter on multipredictor biresponse nonparametric regression model for longitudinal data based on local linear estimator which is applied to data of the case increase and case fatality rates COVID-19 in Indonesia. The estimation result can be used to determine the predictor variable, e.g. temperature which has a significant effect on the case increase and case fatality rates COVID-19 in Indonesia so that it can be advised to the ministry of health to control the case increase and case fatality rates COVID-19 in Indonesia. © 2022 the author(s).
EBG combined isolation slots with a bridge on the ground for noise suppression

ABSTRACT In this paper, a coplanar electromagnetic bandgap (EBG) structure is presented to realise with L-bridge unit cell on the power plane that is combined isolation slots with straight/meander-bridge on the ground plane. The proposed structure with meander-bridge on the ground plane possesses an ultra-wide band gap from 0.22 GHz to 20 GHz with isolation below −30 dB, which is remarkable better than traditional EBG. The lumped equivalent-circuit model for the structure is presented and analysed to explain the mechanism of the improvement of noise suppression. The cut-off frequency for the proposed structure is obtained by theoretical analysis. It is shown that the increase of equivalent inductance of the bridge influences the cut-off frequency. The meander-bridge on the ground plane is adopted to broaden the stopband and significantly enhance the suppression depth. The validity of the presented structure is verified by the simulation compared to the measurement.
The Nine-Item Internet Gaming Disorder Scale (IGDS9-SF): Its Psychometric Properties among Sri Lankan Students and Measurement Invariance across Sri Lanka, Turkey, Australia, and the USA

The prevalence of internet gaming disorders (IGD) is considerably high among youth, especially with the social isolation imposed by the ongoing COVID-19 pandemic. IGD adversely affects mental health, quality of life, and academic performance. The Internet Gaming Disorder Scale (IGDS9-SF) is designed to detect IGD according to DSM-IV diagnostic criteria. However, inconsistent results are reported on its capacity to diagnose IGD evenly across different cultures. To ensure the suitability of the IGDS9-SF as a global measure of IGD, this study examined the psychometric properties of the IGDS9-SF in a sample of Sri Lankan university students (N = 322, mean age = 17.2 ± 0.6, range = 16–18 years, 56.5% males) and evaluated its measurement invariance across samples from Sri Lanka, Turkey, Australia, and the USA. Among Sri Lankan students, a unidimensional structure expressed good fit, invariance across different groups (e.g., gender, ethnicity, and income), adequate criterion validity (strong correlation with motives of internet gaming, daily gaming duration, and sleep quality), and good reliability (alpha = 0.81). Males and online multiplayers expressed higher IGD levels, greater time spent gaming, and more endorsement of gaming motives (e.g., Social and Coping) than females and offline players. Across countries, the IGDS9-SF was invariant at the configural, metric, and scalar levels, although strict invariance was not maintained. The lowest and highest IGD levels were reported among Turkish and American respondents, respectively. In conclusion, the IGDS9-SF can be reliably used to measure IGD among Sri Lankan youth. Because the scale holds scalar invariance across countries, its scores can be used to compare IGD levels in the studied countries.
Trochlear prosthesis and modified leveling osteotomy of the tibial plateau in dogs

Medial patella luxation is a condition resulting from congenital bone deformities that in the long term may result in rupture of the cranial cruciate ligament. These orthopedic ailments are responsible for much of the pelvic limb claudication in dogs and degenerative joint disease. Claudication and joint pain are the main clinical manifestations, and the diagnosis is confirmed by orthopedic examination for both conditions. The simultaneous treatment of these diseases is a challenge for the surgeon. This study reports on the association of trochlear sulcus replacement with prosthesis with modified plateau leveling osteotomy for simultaneous treatment of grade III medial patellar dislocation and cranial cruciate ligament rupture in dogs.
Spatial Difference between Temperature and Snowfall Driven Spring Phenology of Alpine Grassland Land Surface Based on Process-Based Modeling on the Qinghai-Tibet Plateau

As a sensitive indicator for climate change, the spring phenology of alpine grassland on the Qinghai–Tibet Plateau (QTP) has received extensive concern over past decade. It has been demonstrated that temperature and precipitation/snowfall play an important role in driving the green-up in alpine grassland. However, the spatial differences in the temperature and snowfall driven mechanism of alpine grassland green-up onset are still not clear. This manuscript establishes a set of process-based models to investigate the climate variables driving spring phenology and their spatial differences. Specifically, using 500 m three-day composite MODIS NDVI datasets from 2000 to 2015, we first estimated the land surface green-up onset (LSGO) of alpine grassland in the QTP. Further, combining with daily air temperature and precipitation datasets from 2000 to 2015, we built up process-based models for LSGO in 86 meteorological stations in the QTP. The optimum models of the stations separating climate drivers spatially suggest that LSGO in grassland is: (1) controlled by temperature in the north, west and south of the QTP, where the precipitation during late winter and spring is less than 20 mm; (2) driven by the combination of temperature and precipitation in the middle, east and southwest regions with higher precipitation and (3) more likely controlled by both temperature and precipitation in snowfall dominant regions, since the snow-melting process has negative effects on the air temperature. The result dictates that snowfall and rainfall should be concerned separately in the improvement of the spring phenology model of the alpine grassland ecosystem.
A Review about Flux-Weakening Operating Limits and Control Techniques for Synchronous Motor Drives

This paper deals with motor design aspects and control strategies for the flux-weakening (FW) operation of synchronous motors. The theory of FW is described by taking into account different control schemes. The advantages and drawbacks of each one are discussed, as well. Moreover, some motor design considerations for achieving an effective FW operation are illustrated for permanent magnet (PM), wound rotor (WR) and reluctance (REL) synchronous machines, using the per unit approach. The distinguishing characteristic of this review provides two-fold attention on both machine design and control strategies obtained by several collaborations with industrial and commercial companies.
Análisis del índice de temperatura-humedad sobre la mortalidad y el peso corporal de cuyes (Cavia porcellus) de la línea sintética en Moquegua, Perú

En este estudio se analizó la relación de la temperatura (T), humedad relativa (HR) e índice de temperatura-humedad (ITH) sobre la mortalidad y el peso corporal de cuyes (Cavia porcellus) de la línea sintética en la ciudad de Moquegua, Perú. Para ello, se evaluaron 157 cuyes entre octubre del 2019 y marzo del 2020, a través del análisis de la variabilidad y los niveles de asociación entre T, HR, ITH, mortalidad y peso. Los datos fueron procesados en STATA IC14. Los resultados de T, HR e ITH registrados mensualmente mostraron cambios altamente significativos (p < 0,001), al igual que el peso entre machos y hembras (p < 0,05). Los coeficientes de correlación estadísticamente significativos se hallaron entre el peso de cuyes machos y T a la semana 4 (r = -0,345) y a la 6 (r = -0,352); HR, a la semana 4 (r = -0,388) y a la 6 (r = -0,387); e ITH, a la semana 4 (r = -0,387) y a la 6 (r = -0,374). No se demostró correlación entre la mortalidad e ITH (p > 0,05); además, se observó un incremento en la mortalidad en situación de estrés (ITH > 72). El incremento de peso de cuyes machos mostró tendencia lineal a ITH ≤ 72 (r2 = 0,993) e ITH > 72 (r2 = 0,994). De igual manera, el incremento de peso de las hembras mostró tendencia lineal a ITH ≤ 72 (r2 = 0,996) e ITH > 72 (r2 = 0,997).
Analysis and design of class-E power amplifier considering MOSFET nonlinear capacitance

Class-E power amplifiers are integrated into many applications because their simple design and high performance. The efficiency of the power amplifier is significantly impacted by the nonlinear characteristic of the switching device, which is not analyzed clearly in theory. The nonlinear drain-to-source parasitic capacitance of the power transistor and the linear external capacitance are both contributed to the optimum conditions for obtaining the exact shunt capacitance. In this paper, a high-efficiency class-E power amplifier with shunt capacitance is designed with the consideration of both linear and nonlinear capacitance. Furthermore, a mathematical analysis is derived to calculate the component values in order to design the class-E power amplifier. Consequently, high power-added efficiency of 94.6% is obtained using MRF9030 MOSFET transistor with parameter of 4W output power and 13.56 MHz operating frequency. Finally, the measurement result of a linear class-E power amplifier circuit is obtained to compare and realize the efficiency of the proposed work.
Self-powering vibration sensor based on a cantilever system with a single-electrode mode triboelectric nanogenerator

Here, we report a vibration sensor based on a single-electrode mode triboelectric nanogenerator (TENG). The main objective of this study is to develop a vibration sensor (architecture) that can be employed in any application with minor design changes to meet individual objectives. Hence, a cantilever-based vibration system is selected, which offers optimum design control in fine-tuning the sensor to operate in the desired frequency spectrum. The cantilever’s proof mass is suspended by isotropic linear elastic material constituting a scalable and tunable cantilever–mass system. The oscillations create contact separation between the triboelectric-active layers (i.e. fluorinated ethylene–propylene copolymer and screen-printed zinc oxide), which develop triboelectric waveforms. This voltage waveform is used for both sensing and powering mechanisms. At resonance, the device produces peak-to-peak voltage, short-circuit current, and power density of 25 V, 10 µA, and 1.38 W m−2, respectively. To measure the influence of change in cantilever properties, we varied the number of cantilevers and evaluated the sensor performance. The sensor is reliable with >99% accuracy in a broad frequency range of 0–400 Hz. The sensor exhibits a maximum sensitivity of 14 V g−1 and can charge a 1 µF capacitor to 2.75 V in <150 s. The sensor is further tested on a lab-scale vacuum pump with known (induced) faults to estimate the sensor’s competence in detecting the machinery faults. Considering the market acceptability, the sensor is developed with established manufacturing techniques such as screen-printing, and laser cutting. This study hopes to bridge the lab-to-market gap for TENG-based (vibration) sensors.
Formulation Design and Cell Cytotoxicity of Curcumin-Loaded Liposomal Solid Gels for Anti-Hepatitis C Virus

Backgrounds Curcumin (CUR) is a low-molecular-weight polyphenolic substance obtained from the tuber part of Curcuma species. Anti-inflammatory and anti-hepatitis C virus (HCV) activities have been associated with CUR. However, its poor aqueous solubility and low systemic bioavailability have been the challenges in improving the therapeutic efficacy of curcumin. Aim The study aimed to produce CUR-loaded liposomal solid gels as anti-HCV delivery systems. Parameters including the physical characteristics and the cell cytotoxicity properties were evaluated. Methods The freeze-drying technique was applied to manufacture the CUR-loaded liposomal solid gels. Scanning electron microscopy (SEM), X-ray diffractometry (XRD), and differential thermal analysis (DTA) were involved to reveal the characteristics of the solid gels. Such characteristics were as follows: the morphology and the microscopic structure of the solid gels, the crystallinity structure of the curcumin, and the thermal properties of the mixtures. Furthermore, their cell cytotoxicity was investigated using a Huh7it cell line. Results The SEM images confirmed that curcumin liposomes were intact and trapped in the solid gel matrix. The XRD data showed flat patterns diffractograms of the formulations, confirming the transformation of CUR from crystalline to amorphous form. The DTA thermograms showed a single melting endothermic peak at a higher temperature around 200°C, indicating a single-phase transition of the mixtures. The XRD and DTA data revealed the molecular dispersion of CUR in the developed formulations. The cytotoxicity data provided as cell cytotoxicity 50 (CC50) for all formulations were ≥25 mg. These data confirmed that the developed liposomal solid gels were not cytotoxic to Huh7it cell line, indicating that the anti-HCV activity would be through a specific pathway and not by its toxicity. Conclusion The CUR-loaded liposomal solid gels exhibited the potential and offered an alternative dosage form to improve the therapeutic efficacy of curcumin as an anti-HCV.
El castellano de la comunidad shipibo de Cantagallo: estudio acústico de la duración vocálica

Este estudio explora la duración vocálica en el castellano hablado por bilingües shipibo-castellano de la comunidad de Cantagallo. Este análisis se realiza tomando en cuenta el trabajo de Elías Ulloa (2011) quien examina las vocales largas del shipibo a partir de la noción de tamaño mínimo de palabra, requerimiento que no está presente en castellano. Los resultados indican que los hablantes bilingües producen vocales con mayor duración que las de los monolingües. Además, la duración vocálica entre estos bilingües varía dependiendo de su dominancia hacia shipibo o castellano. Por otro lado, sugiero que la naturaleza de las vocales largas producidas en el castellano de los hablantes shipibo podría deberse a la transferencia del requerimiento del peso silábico del shipibo al castellano.
Integration of Multiplied Omics, a Step Forward in Systematic Dairy Research

Due to their unique multi-gastric digestion system highly adapted for rumination, dairy livestock has complicated physiology different from monogastric animals. However, the microbiome-based mechanism of the digestion system is congenial for biology approaches. Different omics and their integration have been widely applied in the dairy sciences since the previous decade for investigating their physiology, pathology, and the development of feed and management protocols. The rumen microbiome can digest dietary components into utilizable sugars, proteins, and volatile fatty acids, contributing to the energy intake and feed efficiency of dairy animals, which has become one target of the basis for omics applications in dairy science. Rumen, liver, and mammary gland are also frequently targeted in omics because of their crucial impact on dairy animals’ energy metabolism, production performance, and health status. The application of omics has made outstanding contributions to a more profound understanding of the physiology, etiology, and optimizing the management strategy of dairy animals, while the multi-omics method could draw information of different levels and organs together, providing an unprecedented broad scope on traits of dairy animals. This article reviewed recent omics and multi-omics researches on physiology, feeding, and pathology on dairy animals and also performed the potential of multi-omics on systematic dairy research.
Implementation of a Virtual Reality recreation program in long-term care

Introduction This manuscript describes the implementation of a Virtual Reality (VR) recreation program at long-term care sites across Ontario, Canada, using the RE-AIM Framework to guide the implementation and its evaluation. Methods We developed a VR recreation program to enhance the lives of long-term care residents, through 3 sequential phases. In Phase 1, we learned about resident and staff needs through focus groups, staff surveys and observations. In Phase 2, we developed 10 VR experiences, based on the data from Phase 1. In Phase 3, we implemented the VR experiences and supporting manual and measured their implementation, using the RE-AIM Framework. Results We found the VR program to be highly (but not consistently) implementable across all sites. Factors that supported implementation were the following: resident interest in the content and technology, relative ease of use for staff to implement and formally integrating VR into the recreation calendar. Factors that impeded implementation were the following: the size of the headset, inability for the headset to cast given the sites' Information Technology infrastructure and some content that was not engaging. Conclusions VR programs are highly implementable and this implementation is enhanced by integration of the program into existing recreational systems, ease of use and resident engagement.
The effect of organizational factors on business growth in international franchises; the caseof Iranian food industry

This paperattempts to investigate the effect ofOrganizational Factorsof international franchising on the growth of businesses in Iran's food industry. Based on the stratified random sampling, we distributed our questionnaires between 80 managers and experts of firms involved in international franchising. Data were analyzed using structural equation modeling and Smart PLS 2 software in two sections of measurement model and structural model. In the first section, the technical features of the questionnaire in terms of reliability, convergent validity, and discriminate validity. Moreover, in the second section, t-values were used for testing the research hypotheses. The results revealed the positive and significant impact of organizational dimension of international franchising including size, management international orientation, and performance experience on the growth of firms in our sample.