Miracle-dz/UniFAR-FTUs huggingface dataset:
Time-harmonic finite element analysis of guided waves generated by magnetostrictive patch transducers

Transducers made of thin magnetostrictive patches and magnetic circuits have been recently developed as an effective means for non-destructive guided wave inspection of elastic structures. However, important characteristics of transducers, such as their wave radiation patterns, have been tested only by experiments or a first-order theoretical analysis. There have been some finite element analyses related to magnetostrictive actuators, but no numerical analysis has been performed to predict the wave radiation patterns of various magnetostrictive patch transducers. In this paper, we formulate a finite element procedure and implement it to predict the wave radiation pattern of a magnetostrictive patch transducer installed on a plate. In particular, a linearized model determining coupling matrix appearing in the magnetostrictive constitutive equation of a magnetostrictive patch in a transducer is developed. The developed model is then used to deal with the arbitrarily polarized static magnetic field induced in the transducers. For numerical efficiency, time-harmonic analysis is carried out and a technique to extract data corresponding to target guided wave modes is used. The validity of the developed finite element analysis is checked by comparing the simulated wave radiation patterns from the present analysis with experimental results. The reasons why certain radiation patterns are obtained for selected magnetic circuits are explained by physical reasoning and simulation results.
Frequency Stabilization for Multi-area Thermal–Hydro Power System Using Genetic Algorithm-optimized Fuzzy Logic Controller in Deregulated Environment

Abstract—This article develops a model of load frequency control for an interconnected two-area thermal–hydro power system under a deregulated environment. In this article, a fuzzy logic controller is optimized by a genetic algorithm in two steps. The first step of fuzzy logic controller optimization is for variable range optimization, and the second step is for the optimization of scaling and gain parameters. Further, the genetic algorithm-optimized fuzzy logic controller is compared against a conventional proportional-integral-derivative controller and a simple fuzzy logic controller. The proposed genetic algorithm-optimized fuzzy logic controller shows better dynamic response following a step-load change with combination of poolco and bilateral contracts in a deregulated environment. In this article, the effect of the governor dead band is also considered. In addition, performance of genetic algorithm-optimized fuzzy logic controller also has been examined for various step-load changes in different distribution unit demands and compared with the proportional-integral-derivative controller and simple fuzzy logic controller.
A Standardized Lindera obtusiloba Extract Improves Endothelial Dysfunction and Attenuates Plaque Development in Hyperlipidemic ApoE-Knockout Mice

Lindera obtusiloba extract (LOE), a traditional herbal medicine used to enhance blood circulation and to reduce inflammation, induced NO-mediated endothelium-dependent relaxation, and reduced the formation of reactive oxygen species (ROS). The study investigated whether LOE improves endothelial dysfunction and reduces plaque inflammation and progression by inhibiting ROS generation in a mouse model of atherosclerosis. Eight-week-old apolipoprotein E-deficient (apoE−/−) mice fed with a western diet (WD) were randomized into different groups by administering vehicle (0.5% carboxymethylcellulose (CMC)), LOE (100 mg/kg/day), or losartan (30 mg/kg/day) by gavage until the age of 28 weeks. Fourteen male C57BL/6 mice that were fed normal chow and treated with CMC were used as negative controls. Similar to losartan treatment, LOE treatment induced the concentration-dependent relaxation of aorta rings in WD-fed apoE−/− mice. LOE treatment significantly reduced the vascular ROS formation and expression of NADPH oxidase subunits, including p22phox and p47phox. Compared with WD-fed apoE−/− mice, mice exposed to chronic LOE treatment exhibited reductions in plaque inflammation-related fluorescence signals and atherosclerotic lesions. These effects were greater than those of losartan treatment. In conclusion, LOE treatment improves endothelial dysfunction and reduces plaque inflammation as well as lesion areas by reducing vascular NADPH oxidase-induced ROS generation in a mouse model of atherosclerosis.
The Complexity of Associative Diffusion: Reassessing the Relationship between Network Structure and Cultural Variation

Goldberg and Stein (2018) present an innovative agent-based computational model that shows how cultural associations can diffuse through superficial interpersonal interactions. They counterintuitively argue that segmented networks—for example, those resembling “small worlds” with dense local clustering—inhibit rather than promote cultural diffusion. This finding is notable because it breaks with a long line of influential research showing that local clustering is crucial to diffusion in cases where behaviors and practices—including cultural beliefs—require multiple reinforcements in order to spread. Replicating Goldberg and Stein’s model, we find this result only holds consistently in settings approximating small-group interactions. In models with larger populations, and where cultural associations require repeated reinforcement through social observation, locally clustered small-world networks can promote global cultural variation as well as globally-connected networks, and sometimes do so better. The complex interactions among parameters that lead to this reversal in Goldberg and Stein’s model are instructive for theoretical models of interpersonal influence.
Stimulus-induced narrow-band gamma oscillations in humans can be recorded using open-hardware low-cost EEG amplifier

Stimulus-induced narrow-band gamma oscillations (30–70 Hz) in human electro - encephalograph (EEG) have been linked to attentional and memory mechanisms and are abnormal in mental health conditions such as autism, schizophrenia and Alzheimer’s Disease. This suggests that gamma oscillations could be valuable both as a research tool and an inexpensive, non-invasive biomarker for disease evaluation. However, since the absolute power in EEG decreases rapidly with increasing frequency following a “1/f” power law, and the gamma band includes line noise frequency, these oscillations are highly susceptible to instrument noise. Previous studies that recorded stimulus-induced gamma oscillations used expensive research-grade EEG amplifiers to address this issue. While low-cost EEG amplifiers have become popular in Brain Computer Interface applications that mainly rely on low-frequency oscillations (< 30 Hz) or steady-state-visually-evoked-potentials, whether they can also be used to measure stimulus-induced gamma oscillations is unknown. We recorded EEG signals using a low-cost, open-source amplifier (OpenBCI) and a traditional, research-grade amplifier (Brain Products GmbH) in male (N = 6) and female (N = 5) subjects (22–29 years) while they viewed full-screen static gratings that are known to induce gamma oscillations. OpenBCI recordings showed gamma response in almost all the subjects who showed a gamma response in Brain Products recordings, and the spectral and temporal profiles of these responses in alpha (8–13 Hz) and gamma bands were highly correlated between OpenBCI and Brain Products recordings. These results suggest that low-cost amplifiers can potentially be used in stimulus induced gamma response detection, making its research, and application in medicine more accessible.
NDUFV1 mutations in complex I deficiency: Case reports and review of symptoms

Abstract Mitochondrial complex I (CI) deficiency is the most common oxidative phosphorylation disorder described. It shows a wide range of phenotypes with poor correlation within genotypes. Herein we expand the clinics and genetics of CI deficiency in the brazilian population by reporting three patients with pathogenic (c.640G>A, c.1268C>T, c.1207dupG) and likely pathogenic (c.766C>T) variants in the NDUFV1 gene. We show the mutation c.766C>T associated with a childhood onset phenotype of hypotonia, muscle weakness, psychomotor regression, lethargy, dysphagia, and strabismus. Additionally, this mutation was found to be associated with headaches and exercise intolerance in adulthood. We also review reported pathogenic variants in NDUFV1 highlighting the wide phenotypic heterogeneity in CI deficiency.
Head speed vs. racket inertia in the tennis serve

An initial study of racket motion in the power serve executed by six tennis players was performed using several rackets with different inertia properties. Both two-dimensional high-speed video and three-dimensional active marker measurement techniques were employed at 4500 and 400 Hz sampling rates, respectively. The results indicate that a decrease in racket inertia, within realistic limits, can significantly increase the head speed achieved by skilled players. The racket’s instantaneous centre of rotation position at impact, with respect to a locally defined frame of reference, was also found to be remarkably consistent for most subjects and all rackets tested. A larger scale study is necessary to confirm or deny these observations, but the initial findings encourage the view that realistic racket service performance comparison tests must take account of the variations in head speed likely to be achieved in play.
Validation procedure for final users applied to automotive environments

The definition of the procedures required to validate computational electromagnetic models is an area of particular interest in the automotive industry. A suitable simulation strategy for vehicle environments will enable a considerable reduction of the EMC testing costs during the design stage. One of the main obstacles to go beyond in the profit of this objective is the lack of standard validation methodologies that allow assessing a suitable level of simulation accuracy. The different ways adopted to validate computational electromagnetics (CEM) could be grouped into three main categories, analytical-to-code, code-to-code and simulation-to-measurement validations. This paper describes the issue of the simulation-to-measurement procedure applied to complex structures such as vehicle environment from the final user point of view. The paper introduces the model description, it includes the numerical technique selected, the modelling strategy adopted and the main characteristics of the models, and later the validation experience is presented.
Route plan evaluation method for personalised passenger information service

AbstractDue to changing expectations of characteristics of mobility demands, public transportation users increasingly require a reduction of both the preparation and travel time, an easier and more pleasant travelling experience as well as route plans based on reliable data. Both international and domestic research is widely concerned with route planning optimization. Exemplary assistance applications are already in operation, but they are only semi-occasionally and slightly personalized. Consequently, there is potential for significant research and development in this area. Our developed method and algorithm evaluates the routes based on the personalised user settings and in this way, the ideal routes can be determined. User preferences are represented in evaluation criteria. The algorithm also manages network modifications and often-changing user preferences. The novelty of our algorithm lies in the more realistic evaluation of the routes appreciably considering both the exact physical properties of the.
Placing myself in a new normalized life: the process of becoming a first-time father. A grounded theory study.

Becoming a first-time father is an important transition period in men's lives that is frequently accompanied by joy and happiness. Engaging fathers has a broader impact on family and community and on fathers' own well-being. This study explores the process of men becoming first-time fathers and the experiences and challenges involved. Seventeen interviews with men in different stages of pregnancy, childbirth, and the postpartum period were carried out. Through a grounded theory design, a novel four-stage theoretical model emerged that represents the journey into first-time fatherhood. These stages are beginning the journey, fatherhood in limbo, facing reality, and settling down. Participants suggested that achieving a new normality was the final stage wherein they finally felt located with a sense of mastering in their fatherhood journey. The novel theoretical approach of addressing the process of men allowed access to their perspectives in a more complete way. Men's needs are different at every phase of the transition to fatherhood, and the use of these findings can help care providers care for every man according to the stage he is facing. This article is protected by copyright. All rights reserved.
SOCIAL MEDIA AND THE STOCK MARKETS: AN EMERGING MARKET PERSPECTIVE

There are numerous studies that examine the impact of social media on the stock market performance but there is a paucity of such evidences from the emerging economies. Today many multinational banks and other financial conglomerates from the developed countries are expanding their operations to the emerging markets, known for their rapid growth. The businesses in developed countries prefer using social media to reach out to their stakeholders. This might be a challenge as emerging markets are very different from the developed markets in terms of infrastructure and stock market development. This study performs the sentiment analysis of the tweets about the Indian companies that are a part of Nifty50 or any sectorial index, for a period of 15 months. The results from the Granger-causalty tests indicate that the Twitter sentiments have a significant relationship with the indices related to the banking and financial sectors of the Indian stock markets. Results from the Impulse Response Function reveal that, on the index returns, the impact of the negative sentiments stays for a longer period of time than the positive sentiments. This study would help businesses use social media effectively for information sharing and dissemination in the new environment.
Eradication of a highly invasive bird, the Common Myna Acridotheres tristis, facilitates the establishment of insurance populations of island endemic birds

Summary Common Myna Acridotheres tristis is considered to be among the world’s most damaging invasive species through disturbance, predation, competition pathogen introduction to native birds and other taxa. Claimed impacts on native birds have often been based on anecdotal reports. More substantive evidence of interference with small-island endemic birds has been reported, but impacts have rarely been quantified or subjected to experimental manipulation. On Denis Island (Seychelles), up to 10% of Seychelles Warblers Acrocephalus sechellensis, and small numbers of Seychelles Fodies Foudia sechellesis and Seychelles Paradise Flycatchers Terpsiphone corvina had head injuries following myna attacks, stimulating an eradication of the mynas. Populations of four species of Seychelles’ endemic birds, introduced to the island to establish insurance populations, were estimated before, during and after the completion of the eradication, permitting assessment of the impact of myna removal on populations of the endemics. Numbers of all four endemics increased following introduction, but increases in the numbers of Seychelles Magpie Robins Copsychus sechellensis and Seychelles Paradise Flycatchers accelerated after >90% of the mynas had been removed. All endemic populations continued to increase during and after completion of the eradication in 2015, and injuries to Seychelles Warblers, Seychelles Fodies, and Seychelles Paradise Flycatchers ceased. Habitat management within a designated conservation zone on the island, into which the endemics were released and subsequently spread to occupy most of the island, also contributed to the endemic birds’ global populations and to their improved conservation status. This study confirms that mynas negatively impact small island populations of endemic birds and suggests that their potential impact has been underestimated. Myna eradication should be considered vital before endangered endemic birds and other taxa susceptible to their negative impacts are translocated to small islands for conservation reasons.
Uterine Preservation Treatments in Sarcomas: Oncological Problems and Reproductive Results: A Systematic Review

Simple Summary Uterine sarcomas can affect patients of reproductive age. In this setting, the chance of a fertility-sparing treatment would allow women to become pregnant. In the literature, only a few experiences of fertility-sparing treatment of uterine sarcomas have been reported; however, the oncological safety and reproductive outcomes remain unclear. The aim of this systematic review is to report and summarize all the published evidence about the fertility-sparing approach in these rare and heterogenous tumors, and to help physicians in making clinical decisions. Abstract Uterine sarcomas are rare cancers, sometimes diagnosed in women of childbearing age. Hysterectomy is the standard treatment in early stages. The option of lesion removal to save fertility is described in the literature, but it is still considered experimental. The objective of this systematic review is to report on the available evidence on the reproductive and oncological outcomes of fertility-sparing treatment in women with uterine sarcomas. PubMed, Scopus and Cochrane Central Register of Controlled Trials were searched between 1 January 2011 and 21 June 2021 for publications in English about women with uterine sarcoma treated with a fertility-sparing intervention. Thirty-seven studies were included for a total of 210 patients: 63 low-grade endometrial stromal sarcomas, 35 embryonal rhabdomyosarcomas of the cervix, 19 adenosarcomas, 7 leiomyosarcomas and 2 uterine tumors resembling an ovarian sex cord. Conservative treatment ensured pregnancy in 32% of cases. In terms of oncological outcomes, relapse was related to histology and the worst prognosis was reported for leiomyosarcoma, followed by low-grade endometrial stromal sarcoma, which relapsed in 71% and 54% of cases, respectively. The highest death rate was associated with leiomyosarcoma (57.1%). This study demonstrated that fertility-sparing treatments may be employed in selected cases of early stage uterine sarcoma.
The N6-Methyladenosine- (m6A-) Associated Genes Act as Strong Key Biomarkers for the Prognosis of Pancreatic Adenocarcinoma

Background Pancreatic adenocarcinoma (PAAD) has become the major cause of cancer-related deaths globally. The m6A (N6-methyladenosine) alteration plays a crucial function in carcinogenesis and tumor progression. The role of genes related to m6A and their expression level in pancreatic cancer is not identified yet. The objective of this research analysis is a demonstration of the m6A RNA methylation regulators based as biomarkers for the PAAD diagnosis. Methods About 23 extensively reported m6A RNA methylation regulators were identified through the Cancer Genome Atlas (TCGA) database. This identification was based on consensus clustering analysis, protein-protein integration (PPI) analysis, risk prognostic model, Cox-regression analysis, String Spearman analysis, and LASSO Cox-regression. Results Herein, we conclude that 23 m6A methylation regulators have a strong link with the clinical and molecular characteristics of PAAD. The three subgroups (1/2) of pancreatic adenocarcinoma were identified using the clustering of 23 m6A regulators. Subgroup cluster 2 had a lower survival rate than the subgroup of cluster 1, and the difference in grades between the two groups was substantial. An assessment was performed using the 23 reported m6A methylation regulators. Eight of these can be used as independent PAAD prognostic markers. The consequences of variable IGF2BP3 expression in PAAD were then investigated further. Conclusions The key finding of this study was that the m6A methylation regulator gene has the main role in pancreatic tumors, and it may be used as a biomarker in the prognosis of the PAAD and for therapy purposes.
Finite element analysis of lossy dielectric waveguides

This paper presents a full-wave analysis of lossy dielectric waveguides using a hybrid vector finite element method. To avoid the occurrences of spurious modes in the formulation, edge elements and first-order nodal finite element basis functions are used to span the transverse and the z components of the electric field, respectively. Furthermore, the direct matrix solution technique with minimum degree of reordering has been combined with the modified Lanczos algorithm to solve for the resultant sparse generalized eigenmatrix equation efficiently. >
Kid-Friendly TODs

Transit-oriented developments, or TODs, are commonly thought to appeal to non-traditional households. This paper reviews experiences with TODs, drawn mainly from Europe, that are kid-friendly. What makes them attractive to families are extensive shared green spaces and playgrounds in lieu of surface parking, no-traffic zones, and ample play spaces and cycling paths. Mixed land uses, high-levels of nearby transit services, and defensible spaces also have appeal. In some instances, higher rents reflect these benefits. Reducing on-site parking requirements and introducing transfer mechanisms that help cover the higher costs of family-size affordable units near rail stops can help promote kid-friendly TODs.
INTEGRATING REGIONAL INNOVATION AND SUSTAINABLE DEVELOPMENT: EXAMPLES FROM THE ESZTERHÁZY KÁROLY COLLEGE

ger is located in Northern Hungary, where decision makers constantly struggle with social and economic problems caused by the challenges of non-sustainable development. This paper presents two examples of how higher education organizations, through market-oriented innovation, can facilitate the economy of the region in getting back on the sustainable orbit. The first part of the paper reports an innovation in tourism education that embraces the renewal of the curriculum and the establishment of an internship hotel, while the second part discusses the successes and difficulties of technology transfer from the Egerfood Regional Knowledge Centre to the food industry.
Digging Deeper: Advancements in Visualization of Inhibitory Synapses in Neurodegenerative Disorders

Recent research has provided strong evidence that neurodegeneration may develop from an imbalance between synaptic structural components in the brain. Lately, inhibitory synapses communicating via the neurotransmitters GABA or glycine have come to the center of attention. Increasing evidence suggests that imbalance in the structural composition of inhibitory synapses affect deeply the ability of neurons to communicate effectively over synaptic connections. Progressive failure of synaptic plasticity and memory are thus hallmarks of neurodegenerative diseases. In order to prove that structural changes at synapses contribute to neurodegeneration, we need to visualize single-molecule interactions at synaptic sites in an exact spatial and time frame. This visualization has been restricted in terms of spatial and temporal resolution. New developments in electron microscopy and super-resolution microscopy have improved spatial and time resolution tremendously, opening up numerous possibilities. Here we critically review current and recently developed methods for high-resolution visualization of inhibitory synapses in the context of neurodegenerative diseases. We present advantages, strengths, weaknesses, and current limitations for selected methods in research, as well as present a future perspective. A range of new options has become available that will soon help understand the involvement of inhibitory synapses in neurodegenerative disorders.