Miracle-dz/UniFAR-FTUs huggingface dataset:
Geochemical and Taphonomic Signatures of Freshwater Mussel Shells as Evidence of Mercury-Related Extirpations in the North Fork Holston River, Virginia

This study utilized freshwater mussel shells to assess the role of mercury contamination in the North Fork Holston River, an aquatic habitat affected by extensive extirpations of mussel populations starting in the early 1970’s. Mussel shells (n=366) collected from 5 sites, upstream and downstream of Saltville (where mercury was used from 1950-1972) were analyzed to test if: (1) geochemical signatures of shells record variation in mercury levels relative to the contamination source; and (2) shell taphonomy could be used to differentiated affected and unaffected sites. Analysis of 40 shells for geochemical signatures using atomic absorption spectroscopy indicated a strong longitudinal pattern. Mercury content was as follows: upstream sites had low Hg concentrations (<5 to 31ppb), shells directly below Saltville had high concentrations (23-4,637ppb), shells 18km downstream of Saltville displayed intermediate values (7-115ppb), and those 38.4km downstream were comparable to upstream sites (<10ppb). Two pre-industrial shells collected from Saltville in 1917 also yielded Hg estimates (5-6ppb) comparable with upstream estimates. The Hg content was not correlated with shell length (r=-0.3; p=0.2) or degree of taphonomic alteration (r=0.18; p=0.28). Analysis of 366 shells for taphonomic signatures indicated that shells are most heavily altered and fragmented directly downstream of Saltville. In contrast, upstream sites, inhabited by reproducing mussel populations, contain many fresh-dead shells. Taphonomic signatures can thus be used to differentiate sites with different extirpation histories. Relic mussel shells can provide useful spatial and temporal data on Hg concentrations in polluted ecosystems and offer a tool for delineating areas with unknown extirpation histories.
Spherically Symmetric Static Configurations of Uniform Density in Spacetimes with a Non-Zero Cosmological Constant

Interior solutions of Einstein's equations with a non-zero cosmological constant are given for static and spherically symmetric configurations of uniform density. The metric tensor and pressure are determined for both positive and negative values of the cosmological constant. Limits on the outer radius of the interior solutions are established. It is shown that, contrary to the cases of the limits on the interior Schwarzschild and Reissner--Nordstr\"om solutions with a zero cosmological constant, these limits do not fully coincide with the conditions of embeddability of the optical reference geometry associated with the exterior (vacuum) Schwarzschild--de Sitter spacetime.
Hydrogeological characterisation of crystalline basement aquifers within the Limpopo Province, South Africa

ions from storage indicate on the other hand non-equilibrium conditions. Where the abstraction is greater than the difference between the maximum inflow (R+∆R) and residual outflow (D) then an additional mining yield (change in S) is required to maintain the abstraction rate (Figure 2.14). It must be emphasized that the spatial distribution of these abstraction points strongly influences the total sustainable basin yield. Withdrawals from an aquifer might have a severe impact on individual ecosystems locally, but per square kilometre these withdrawals might R + ∆R = D + Q + S ((∆h/∆t) ∆R = D + Q, or Q = ∆R ∆D R = D (+ Q) Q (Abstraction) = 0 Pristine System Developed System Mining of System Captured Storage (∆h/∆t) Natural Recharge (R) Natural Discharge (D) Captured Recharge (∆R) Natural Recharge (R) Captured Discharge (∆D) Residual Discharge (D) Captured Recharge (∆R) Natural Recharge (R) Captured Discharge (∆D) Residual Discharge (D)
Origin of gypsiferous intrusions in the Hawasina Window, Oman Mountains: Implications from structural and gravity investigations

Gypsiferous intrusions are exposed in road-cuts in the south-central Hawasina Window in the central Oman Mountains. They are located at lower structural levels in the allochthonous Hawasina Complex and lie along faults that cut Upper Cretaceous structures related to the obduction of the Semail Ophiolite and Hawasina Complex deep-water sediments onto the Arabian Plate. The intrusions form gypsiferous pods that are up to 200 m long, in which the gypsum occurs as a dark, fine-grained matrix that contains a pervasive network of anastomosing veins of gypsum and anhydrite. The intrusions contain abundant sub-angular to sub-rounded litharenites, and less common fragments of chert and fine-grained limestone. Although these clast types are undated, their petrographic characteristics suggest they originate from the local Hawasina (Hamrat Duru Group) country rock. Very well-rounded pebbles and cobbles of feldspathic litharenites, some of which show a well-developed cleavage, and rarer cobbles of well-rounded vein quartz appear to have come from the basement. Gravity investigations indicate salt diapirs are not present beneath the Hawasina Window. Instead, the gypsiferous intrusions are interpreted as having been brought up from depth during compression to form disconnected pods along deep-rooted faults, bringing with them small amounts of the basement country rock. Strontium isotope analysis and regional considerations, in particular the distribution, age and nature of other evaporite units on the eastern Arabian Plate, suggest the gypsum may have its origins in the Neoproterozoic (Ediacaran) to lower Cambrian Ara Group evaporites, perhaps from a previously unknown extension of the Fahud Salt Basin beneath the Hawasina thrust sheets.
Incident of Foodborne Illness Associated with Ingestion of an Intentionally Contaminated Soft Drink, Sanford, Florida, August 2006

Introduction On August 10, 2006, the Seminole County Health Department (Seminole CHD) received notification from the Florida Department of Business and Professional Regulation (DBPR) of a complaint of illness in a person who alleged that bleach was placed in her drink while working at a food service facility in Sanford, Florida. Symptoms were initially reported as dizziness, numbness, burning in the throat, shaky and blurred vision. Onset of symptoms was reported to have occurred within five minutes of consuming a beverage obtained from the food service establishment.
A CHILDREN’S GEOGRAPHY OF OCCUPATION: IMAGINARY, EMOTIONAL, AND EVERYDAY SPACES OF PALESTINIAN CHILDHOOD

OF DISSERTATION A CHILDREN’S GEOGRAPHY OF OCCUPATION: IMAGINARY, EMOTIONAL, AND EVERYDAY SPACES OF PALESTINIAN CHILDHOOD This research examines the political geographies of Palestinian children, and the ways in which their everyday spaces and practices are shaped by broader social and political processes. This research begins with an investigation into the role of the child in the moral geopolitics of humanitarianism and the Palestinian/Israeli conflict. From here, the research explores how the competing discourses of Palestinian nationalism and international humanitarianism, and the legacy of forced migration, have shaped the subjectivity of Palestinian children and the spaces of childhood in a West Bank refugee camp, from homes, to schools, streets, and youth centers. Finally, using participant observation, visual methods and guided tours, this research explores how children reshape the discursive spaces of childhood and child subjectivity through their everyday practices.
Comparative Study of Radiation Pattern of Some Different Type Antennas

In this we report radiation pattern of some important antennas as well as area covered by them. The paper starts by giving the reader a refresher on antenna pattern parameters and then shows typical patterns for the most common antennas used in EMC. As the improvements on the communication and navigation systems of aircrafts go on, new edge cutting technologies are developed and new approaches to the system components are required. The antenna represents the interface between the transmitted and/or received microwaves traveling on free space and the signal processing hardware and software. Optimizing the antenna characteristics can lead to great improvements to the overall system performance, like lower noise figures, suppressed multipath and interference signals and higher signal levels, i.e. better accuracy, better aerodynamics, lighter weight, etc. The peak value of radiation for A1 dipole L/2 antenna is typically 63.2 dB μA at 95. For A6 telescopic antenna the value of high radiation along space is 54.9 μA at 75. A2 folded dipole L/2 antenna and A6 telescopic antenna shows similar directional property along at an angle 75 of 360 space. There is very low variation in radiation pattern for A4 loop L/4 antenna along 360.
Myths about People at Work: A Critique of Human-Resource Management

During the period the topic of human-resource management exploded in popularity in large organizations around the world. Continuous requests for consulting came to me and I watched my peers in industry and in full-time consulting make large salaries, but still something felt wrong. A basic conflict grew between what I had learned about organizations from empirical research and what I taught my students from personnel textbooks. Professors of organizational behavior in business schools have created and perpetuated a series of myths about people at work. The purpose of this paper is to summarize briefly the mythology of human-resource management and to describe the contradictory empirical reality. At the conclusion, I will summarize the common elements of the mythology, propose a political explanation for the specific content of myths, and suggest an alternative system of human-resource management. Methodology This paper sets out a personal research agenda for the next year. Therefore , I state my best understanding of empirical reality as a contrast to each myth. Next year I will report how completely the world supports my interpretation. I welcome any evidence on these subjects, whether it be scholary research or anecdotes of organizational practice. Of course, please don't cite this paper as evidence against popular myths, however plausible my argument may sound. The report of my research will be more cautious, lengthier and better documented than this polemic.
Self-rated health: caught in the crossfire of the quest for 'true' health?

This issue of the International Journal of Epidemiology features three papers that assess the predictive power of self-rated health (SRH) for mortality between various socio-economic groups, respectively within three developed countries (France, The Netherlands and the United States). The studies published in this issue follow in the footsteps of Burstrom and Fredlund and Van Doorslaer and Gerdtham who found that the association of SRH with mortality does not differ by either occupational group or income in Sweden. However, the similarities end there, as all the studies presented here found some evidence for a modifying effect of socio-economic status (SES) on the relationship between SRH and mortality, albeit with gradients in sometimes opposite directions. Mixed findings such as these could be—misleadingly—taken as evidence that SRH is not a reliable measure of health for the study of social inequalities in health; instead, in this editorial, I will show how these differences provide fruitful insights for understanding how individuals assess their own health and thus point the way towards a need for more research designed to test these specific hypotheses.
(L)-Semigroup Sums

An (L)-semigroup S is a compact n-manifold with connected boundary B together with a monoid structure on S such that B is a subsemigroup of S. The sum S + T of two (L)-semigroups S and T having boundary B is the quotient space obtained from the union of S × { 0 } and T × { 1 } by identifying the point ( x , 0 ) in S × { 0 } with ( x , 1 ) in T × { 1 } for each x in B. It is shown that no (L)-semigroup sum of dimension less than or equal to five admits an H-space structure, nor does any (L)-semigroup sum obtained from (L)-semigroups having an Abelian boundary. In particular, such sums cannot be a retract of a topological group.
Sédimentologie et métallogénie du Trias et du Lias carbonaté de la bordure cévenole : minéralisations Zn-Pb des paléokarsts sinémuriens de Durfort

Les series essentiellement continentales, detritiques, du trias et carbonatees du lias inferieur et moyen de la bordure cevenole contiennent de nombreux indices et gisements de zn-pb. Dans la premiere partie, on presente la methodologie et on reconstitue le cadre geologique detaille. La deuxieme partie est consacree a l'analyse sedimentologique des quatre formations du groupe triasique et de la formation du lias carbonate, subdivision du groupe liasique; des reconstitutions paleogeographiques sont proposees pour chacune des unites qui constituent les formations. Plus de cinq surfaces paleokarstiques primaires superposees ont ete mises en evidence dans l'unite 4 (sinemurien inferieur); elles contiennent une mineralisation en zn-pb, precoce. De nombreux depots de tempetes et des depots mixtes sont aussi decrits. Dans la troisieme partie, on developpe la gitologie et la metallogenie, en decrivant plus particulierement les paleokarsts de l'unite 4 de durfort et en proposant un modele genetique qui integre les donnees de la sedimentologie et fait intervenir des phenomenes exogenes
The Cerebellum and its Disorders: Dentatorubral-pallidoluysian atrophy

A rare, autosomal dominant inherited progressive neurodegenerative disorder. It is caused by a mutation in the AT N1 gene, resulting in a combined degeneration of the dentatorubral and pallidoluysian systems. It can appear at any age, but it usually affects individuals between 20 and 30 years and leads to death within 10-15 years. T he clinical presentation depends on the age of the affected individual; juvenile patients develop severe progressive myoclonus epilepsy and cognitive decline, whereas adult patients develop ataxia, choreoathetosis and dementia. Qeios · Definition, February 2, 2020
LABORATORY AND FIELD EVALUATION OF THE INSECT GROWTH REGULATOR PYRIPROXYFEN (SUMILARV 0.5G) AGAINST DENGUE VECTORS

ABSTRACT The insect growth regulator pyriproxyfen was tested against Aedes aegypti at 0.01 and 0.02 mg of active ingredient (AI) per liter of water in 60-liter earthern jars. Both concentrations provided 100% control for 4 months. In additional experiments where 10 liters of water were replaced fortnightly, 100% control was still obtained over 4 months with 0.02 mg AI/liter and greater than 93–100% control was obtained over 4 months with 0.01 mg AI/liter. In less-controlled field-trial conditions, pyriproxyfen at a dosage of 0.02 mg AI/liter provided 100% control for 10 wk against Aedes albopictus even though water was replaced either daily or weekly. Although the activity of pyriproxyfen declines after 10 wk, those tests in the plastic tubs showed much higher levels of sustained residual activity compared to those in the earthern jars. Pyriproxyfen did not have an impact on nontarget organisms.
improving medication management after a hospitalization with pharmacist home visits and electronic personal health records: an observational study

Background: Substantial opportunity exists to improve medication management in the period following a hospital discharge. The objective of this study was to assess and improve medication management during care transitions through pharmacist home visits and the use of an electronic personal health record (ePHR) system. Methods: Recently discharged patients aged 50 years or older and having a chronic medical condition were offered the opportunity to meet with a pharmacist in the home setting to review medication instructions and receive a demonstration of an ePHR system. Patients agreeable to using the ePHR system were offered pharmacist support with setting up the ePHR system, having emphasis on documenting and reviewing medication regimens. Medication-related problems identified by the pharmacist during the visit were categorized according to ePHR use and by other characteristics. Results: Thirty recently discharged patients with chronic disease were visited by a pharmacist over a 6-month period. The percentage of medication-related problems identified by the pharmacist was greater among those patients who agreed to use the ePHR system, as compared with patients whose visit did not include use of the ePHR (75% versus 40%, respectively; P = 0.06). Differing types of medication-related problems were identified, including therapy duplications, lack of use of clinically important therapies, and patient nonadherence. Conclusion: For some patients, the home setting can be a suitable venue for medication review and education after discharge from hospital. Assisting patients with setting up the ePHR system may enhance pharmacists’ ability to identify and resolve medication-related problems that may lead to rehospitalization.
Quantification of glutathione with high throughput live-cell imaging

Reduction oxidation (redox) reactions are central in life and altered redox state is associated with a spectrum of human diseases. Glutathione (GSH) is the most abundant antioxidant in eukaryotic cells and plays critical roles in maintaining redox homeostasis. Thus, measuring intracellular GSH level is an important method to assess the redox state of organism. The currently available GSH probes are based on irreversible chemical reactions with glutathione and can’t monitor the real-time glutathione dynamics. Our group developed the first reversible reaction based fluorescent probe for glutathione, which can measure glutathione levels at high resolution using a confocal microscope and in the bulk scale with a flow cytometry. Most importantly it can quantitatively monitor the real-time GSH dynamics in living cells. Using the 2nd generation of GSH probe, RealThiol (RT), this study measured the GSH level in living Hela cells after treatment with varying concentrations of DL-Buthionine sulfoximine (BSO) which inhibits GSH synthesis, using a high throughput imaging system, Cytation™ 5 cell imaging reader. The results revealed that GSH probe RT at the concentration of 2.0 µM accurately monitored the BSO treatment effect on GSH level in the Hela cells. The present results demonstrated that the GSH probe RT is sensitive and precise in GSH measurement in living cells at a high throughput imaging platform and has the potential to be applied to any cell lines.
Clones, polymorphisms and relations of arity omega

Polymorphisms of arity ω have recently been used in the proof of model theory results that have applications in the ﬁeld of complexity of CSP problems. At the same time, the introduction of clone algebras has revitalised the algebraic study of clones of functions, and in particular of functions of arity ω . In this paper, we delve into the algebraic and topological study of polymorphisms of arity ω and of the corresponding invariant relations.
Productivity of the ocean : present and past : report of the Dahlem Workshop on Productivity of the Ocean, Present and Past, Berlin 1988, April 24-29

Ocean productivity and paleoproductivity - an overview, W.H. Berger et al food web structure and loss rate, R.Peinert hydrodynamical singularities as controls of recycled versus export production in oceans, L.Legendre and J.Le Fevre is the downward dissolved organic matter (DOM) flux important in carbon transport? , J.R. Toggweiler new production - history, methods, problems, R.W. Eppley export productivity from the photic zone, P.J.B.Williams et al regional extremes in particulate matter composition and flux - effects on the chemistry of the ocean interior, J.K. B.Bishop particle flux in the ocean - effects of episodic production, G.Wefer does Mesopelagic biology affect the vertical flux? , M.V. Angel how much shelf production reaches the deep sea? , J.J.Walsh flux to the seafloor, P.K. Bienfang et al control of Benthic fluxes by particulate supply, C.E. Reimers responses of benthos to changing food quality and quantity, with a focus on deposit feeding and bioturbation, P.A. Jumars and R.A. Wheatcroft productivity record in Benthic foraminifera, A.V. Altenbach and M.Sarnthein lipid biomarkers as geochemical tools for paleoceanographic study, F.G. Prahl and L.A. Muehlhausen transformation of seafloor-arriving fluxes into the sedimentary record, A.V. Altenbach et al pleistocene paleoproductivity - evidence from organic carbon and foraminiferal species, A.C. Mix tertiary cooling steps and paleoproductivity as reflected by diatoms and biosiliceous sediments, J.A. Barron and J.G. Baldauf inventory of paleoproductivity records - the mid-cretaceous enigma, H.R. Thierstein phosphorus versus nitrogen limitation of new and export production, L.A.Codispoti paleoproduction and atmospheric CO2 based on ocean modeling, R.S. Keir geological reconstructions of marine productivity, T.D. Herbert et al. Appendix: global maps of ocean productivity, W.H. Berger.
Inference for Continuous Semimartingales Observed at High Frequency

The econometric literature of high frequency data often relies on moment estimators which are derived from assuming local constancy of volatility and related quantities. We here study this local-constancy approximation as a general approach to estimation in such data. We show that the technique yields asymptotic properties (consistency, normality) that are correct subject to an ex post adjustment involving asymptotic likelihood ratios. These adjustments are derived and documented. Several examples of estimation are provided: powers of volatility, leverage effect, and integrated betas. The first order approximations based on local constancy can be over the period of one observation or over blocks of successive observations. It has the advantage of gaining in transparency in defining and analyzing estimators. The theory relies heavily on the interplay between stable convergence and measure change, and on asymptotic expansions for martingales. Copyright 2009 The Econometric Society.
Characterization of Hedgehog Acyltransferase Inhibitors Identifies a Small Molecule Probe for Hedgehog Signaling by Cancer Cells

The Sonic Hedgehog (Shh) signaling pathway plays a critical role during embryonic development and cancer progression. N-terminal palmitoylation of Shh by Hedgehog acyltransferase (Hhat) is essential for efficient signaling, raising interest in Hhat as a novel drug target. A recently identified series of dihydrothienopyridines has been proposed to function via this mode of action; however, the lead compound in this series (RUSKI-43) was subsequently shown to possess cytotoxic activity unrelated to canonical Shh signaling. To identify a selective chemical probe for cellular studies, we profiled three RUSKI compounds in orthogonal cell-based assays. We found that RUSKI-43 exhibits off-target cytotoxicity, masking its effect on Hhat-dependent signaling, hence results obtained with this compound in cells should be treated with caution. In contrast, RUSKI-201 showed no off-target cytotoxicity, and quantitative whole-proteome palmitoylation profiling with a bioorthogonal alkyne-palmitate reporter demonstrated specific inhibition of Hhat in cells. RUSKI-201 is the first selective Hhat chemical probe in cells and should be used in future studies of Hhat catalytic function.