Miracle-dz/UniFAR-FTUs huggingface dataset:
Branding and Repositioning Approaches for Hotels: a Case Study

Over the years it has been observed that consumer needs and desires are constantly changing. Businesses investigate consumer behavior and then take actions to satisfy them while giving more value to their customers. On the other hand, the ever-increasing competitiveness and mass consumption are driving businesses to take action in order to help them survive and gain a good competitive edge. Many times, this approach deems it necessary to implement a positioning process, which in combination with highlighting a brand's elements leads to differentiation. When the brand does not meet these market demands, then its consumption decreases, resulting in a decline. However, the company has the ability to modify the brand before it goes bankrupt and re-launch it with different features, after of course investigating what led the brand to this situation. In some cases, in which positioning was not done in the appropriate way, business often are driven to repositioning, changing many of the brand's elements. Repositioning is a conscious adaptation to a changing environment, which represents a fundamental change in the value of the business. It can be described also as a parallel to the recovery as both focus on improving the business value proposition. Although the literature is not extensive, its meaning can be found in a wide range of strategic references. Repositioning has been seen as a key prerequisite for achieving change, as an element at the corporate level and as a strategic response to dynamic environments. The study in this article is based on relevant literature and on a case study about the repositioning of the Plaza Hotel in Thessaloniki. Qualitative research through a semi-structured in-depth personal interview was used in order to find the necessary data and to draw the right conclusions. In addition, it clarifies the way it operates today, as well as the changes that have been made to achieve the desired development result, making it one of the most reliable and trusted hotels in the city.
Frequency of Mold Allergens in Allergic Rhinitis Patients

s S85. 19. Aburuz S, Bulatova N, Tawalbeh M. Skin prick test reactivity to aeroallergens in Jordanian allergic rhinitis patients. Eastern Mediterranean Health Journal 2011; Vol 17(7): 604-610. 20. Kashef S, Kashef M.A, Eghtedari F. Prevalence of Aeroallergens in Allergic Rhinitis in Shiraz.Iranian Journal of Alllergy , Asthma and Immunology 2003 Vol
Modulation and function of microglial phenotypes

Microglia are the sentinel cells of the retina, where they are involved in surveillance of tissue integrity and clearance of cellular debris. The innate immune functions of microglia are tightly controlled by retinal neurons via the secretion of suppressing factors to prevent harmful pro-inflammatory activation. Progressive retinal cell death is a common sink of all inherited retinal diseases, causing perturbance of the retinal tissue homeostasis. This leads to pro-inflammatory microglial activation, a mutual event of all retinal dystrophies. Sustained microglial activation is considered to exacerbate the progression of retinal disease. Gene therapy is a current strategy aiming to cure inherited retinal degenerative diseases. In contrast to this individualized approach, modulation of microglial activity is independent of the causative genetic defect and therefore provides a broad therapeutic range. Local application of microglia-regulating proteins or the supplementation of anti-inflammatory plant-derived compounds could be envisioned for the treatment of degenerative retinal diseases. Transcriptional profiling of retinal microglia led to the identification of the novel whey acidic protein AMWAP. Based on the known properties of other myeloid-derived whey acidic proteins, we assumed that AMWAP could modulate microglial activity. Functional analyses then revealed that AMWAP has several immuno-regulatory effects. AMWAP effectively inhibts serine-proteases, has broad anti-microbial potential and dampens transcript levels of pro-inflammatory marker genes. AMWAP also induces expression of alternative marker genes associated with neurotrophic functions. The results presented in this work propose that AMWAP could be a potential therapeutic tool to dampen microglial activation and attenuate retinal degeneration. Compounds from plant extracts like Curcumin and Luteolin have been widely used in traditional chinese medicine, because they have well known anti-inflammatory and radical scavenging activities. As part of this work, we analyzed the modulatory effects of Curcumin and Luteolin on pro-inflammatory activated microglial cells by transcriptomic profiling. The assessment of global gene expression showed indications for reprogramming of the pro-inflammatory activated microglia phenotype. Curcumin and Luteolin attenuated pro-inflammatory activation of microglia and concurrently induced the expression of neuroprotective markers with substance-specific gene signatures. Subsequent functional analysis of microglia treated with both compounds in vitro revealed profound neuroprotective features. In conclusion, both plant-derived polyphenolic compounds may be promising tools to counter-act neurotoxic microglial activation in retinal disease.
Assembly of Iron-Sulfur Clusters In Vivo

Iron-sulfur [Fe-S] clusters are protein cofactors that facilitate various life-sustaining biological processes. Their in vivo assembly is accomplished by three different systems known to date. These are: the NIF system which provides [Fe-S] clusters for nitrogenase and other nitrogen-fixing proteins, the SUF system which is induced during conditions of oxidative stress and iron starvation in E. coli, and the ISC system which serves as the housekeeping assembly apparatus. The latter is the focus of this dissertation and includes the proteins IscR, IscS, IscU, IscA, HscB, HscA, Fdx, and IscX. IscU is purified in its cluster-less (apo) form, but can serve as a scaffold to assemble [Fe-S] clusters in vitro in the presence of excess iron and sulfide. To test the scaffold hypothesis and gain insight into the events that occur during [Fe-S] cluster assembly and delivery, we developed two methods that allow the isolation of IscU and other ISC proteins in vivo. In the first method, Azotobacter vinelandii IscU is isolated from its native host, whereas in the second, it is isolated recombinantly from E. coli using a vector that allows expression of the entire isc operon. We found that IscU exists in vivo in two forms: apo-IscU and [2Fe2S] cluster-loaded IscU which are believed to be conformationally distinct. Both transient and stable IscU-IscS complexes were identified, indicating that the two proteins interact in vivo in a manner that involves their association and dissociation. The [2Fe2S]-IscU species was present as a single entity, whereas significant amounts of apoIscU were found associated with IscS, suggesting that IscU-IscS dissociation is triggered by the completion of [2Fe-2S] clusters. Both apo and [2Fe-2S]-IscU were predominantly monomeric whereas IscU-IscS complexes were determined to have an α2β2 composition. IscU was purified in the absence of the chaperones HscA and HscB and was also shown to accommodate a [2Fe-2S] cluster similar to the one bound to IscU isolated from wild type cells. The findings suggest that [2Fe-2S]-IscU exists in one conformation in vivo and that any conformational changes on IscU are exerted after
Learning the Best Pooling Strategy for Visual Semantic Embedding

Visual Semantic Embedding (VSE) is a dominant approach for vision-language retrieval, which aims at learning a deep embedding space such that visual data are embedded close to their semantic text labels or descriptions. Recent VSE models use complex methods to better contextualize and aggregate multi-modal features into holistic embeddings. However, we discover that surprisingly simple (but carefully selected) global pooling functions (e.g., max pooling) outperform those complex models, across different feature extractors. Despite its simplicity and effectiveness, seeking the best pooling function for different data modality and feature extractor is costly and tedious, especially when the size of features varies (e.g., text, video). Therefore, we propose a Generalized Pooling Operator (GPO), which learns to automatically adapt itself to the best pooling strategy for different features, requiring no manual tuning while staying effective and efficient. We extend the VSE model using this proposed GPO and denote it as VSE∞. Without bells and whistles, VSE∞ outperforms previous VSE methods significantly on image-text retrieval benchmarks across popular feature extractors. With a simple adaptation, variants of VSE∞ further demonstrate its strength by achieving the new state of the art on two video-text retrieval datasets. Comprehensive experiments and visualizations confirm that GPO always discovers the best pooling strategy and can be a plug-and-play feature aggregation module for standard VSE models. Code and pre-trained models are available at http://jcchen.me/vse_infty/
Coconut Neera—A Vital Health Beverage from Coconut Palms: Harvesting, Processing and Quality Analysis

Nature has made nutritive products in such a way that it cannot be manufactured in laboratories or in mills. Coconut Neera is the natural sap of the mature coconut palms rich with all essential nutrients, minerals and vitamins for human health. Harvesting of Neera from the spadix of the palms without disturbing the physiology of the tree has a lot of potential at the industrial scale. However, the development of alcohol in the extracted sap during tapping by auto-fermentation has given a misnomer for Neera as “sweet toddy”. Hence, the commercial popularity of Neera as a health drink has diminished at a global level. Though several traditional techniques like the usage of calcium hydroxide (lime) and the application of the chiller device during harvesting Neera from spadix have been practiced for collecting non-fermented Neera, none of the techniques were found acceptable at the commercial level. The results of the present study demonstrate the harvesting and processing procedure standardized for the collection and storage of non-fermented Neera from palms by repeated field trials. The cumulative effect of the anti-fermentation solution (AFS) with the presence of the two preservatives—citric acid (5 mM) and potassium metabisulphite (2 mM)—by preventing fermentation from the level of harvesting to processing was confirmed. The zero content of alcohol in raw Neera indicates the AFS action. The proximate composition of primary constituents and the content of minerals, amino acids and vitamins present in Neera highlights its nutrient value as a health beverage. The higher content of minerals—sodium and potassium (15.2 mg and 100 mg), the elevated level of amino acids-cysteine (14 mg), tyrosine (7.11 mg), arginine (7 mg) and the presence of vitamin C (65 mg) and vitamin A as retinol (4.88 IU)—indicates the therapeutic importance of coconut Neera. The data of oral toxicity and the glycemic index further support the vital quality.
Ascorbic Acid and Vitamin A Activity in Selected Vegetables from Different Geographical Areas of the United States

Reduced ascorbic acid (RAA) and Vitamin A (carotenoid) contents of six vegetables obtained from six cities in the United States at two seasons of the year were determined. Mean RAA content (mg/lOOg) of cabbage was 45.2, carrots 7.8, celery 6.0, corn 6.5, onions 8.4, and tomatoes 15.3. Vitamin C in cooked cabbage was 22.1, corn 6.2, and onions 5.7 mg/100g. Mean vitamin A activity (I.U.) of car- rots was 15,228, cabbage 114, celery 133, corn 219, and tomatoes 750. In cooked cabbage and corn, vitamin A content was 89 and 217 I.U. , respectively. The RAA and vitamin A content of vege- tables from the six geographical areas varied significantly. Vitamin concentrations were generally lower than tabulated values. Reten- tion of RAA in cooked cabbage was 52%; in onions, 58%; and in corn, 98%. Vitamin A retention in cooked cabbage was 82%, and in cooked corn was 98%. cities, at two different seasons. The vegetables were obtained from six different areas in the United States: West (Seattle and Denver), Midwest (St. Louis and Minneapolis), and East (Boston and Atlanta), at two different times of the year. The source of the vegetables, including the gowing area (when known), and the months they were obtained, are given in Table 1. Produce typical of that being sold in each area was shipped directly to the University of Illinois via air freight to Champaign-Urbana, IL, stored at 4"C, and pre- pared for analysis within 48 hr of shipment. Tomatoes in some cases were held at room temperature (24°C) to ripen. The times and conditions during shipping were similar to what is encountered in transport from warehouses to market outlets. Sampling procedures All vegetables were analyzed raw, and cabbage, corn and onions were also cooked and analyzed. The vegetables were trimmed, peeled if necessary, washed in deionized distilled (DD) water, and blotted dry. Approximately 15-20 kg of each vegetable were sliced (carrots, celery, onions) or cut in eighths (tomatoes, cabbage). The samples for cooking and analyses were drawn from these com- posites. Approximately 7.5-10 kg of each vegetable were cooked by the methods given below. The cooked vegetables were combined and samples drawn from the composite for nutrient assay. Corn was husked, rinsed and blotted dry, and then cut from the cob for the raw samples. Corn was cooked on the cob and the kernels removed for the cooked samples. All cutting implements used were stainless steel, and care was taken to avoid contamination with minerals. Duplicate or triplicate determinations were performed for every nutrient for each raw or cooked vegetable at each sampling period from all of the geographical areas. Cooking methods
Lanthanides to Probe Metal-induced Structural and Dynamic Changes in EcoRV-DNA Complex

Protein-DNA interactions regulate key biological processes such as gene expression, genetic recombination, DNA synthesis and repair. DNA binding proteins that are enzymes often depend on metal ions (typically Mg2+) for catalysis. Metal ions neutralize the active site electrostatic repulsion generated by a constellation of negatively charged active site residues. They therefore enhance site-specific protein-DNA binding by making the interaction more energetically favorable. Although, specific protein-DNA-metal complexes have been studied extensively by various biophysical and biochemical methods, little is known about the dynamics of these complexes. Many crystal structures of protein-DNA-metal complexes are available but they are very similar to the metal-free structures and show little or no change due to metal-ion binding. Therefore, to understand the altered energetics of protein-DNA recognition complexes due to metal-ion binding, it is essential to study them in solution. In our study, we have used EcoRV-DNA complex, with Lu3+ as the metal ion, to detect metal-induced structural and/or dynamic changes in solution using paramagnetic relaxation enhancement (PRE). Lu3+ inhibits Mg2+ dependent DNA hydrolysis in EcoRV, stimulates EcoRV-DNA affinity, binds in the same site and with the same stoichiometry as Mg2+ and is therefore an excellent substitute for Mg2+. In addition, to verify that Lu3+ binding is confined to the active sites, we have solved crystal structures of the EcoRV-DNALu3+ complex with uncleaved and cleaved DNA. Also, for a comprehensive residue-specific analysis, we have acquired both backbone NH and methyl side-chain (ILV) assignments for EcoRV-DNA complex with and without Lu3+. In order to detect metal-induced changes in
Multiple Lower Cranial Nerve Palsies Due to Nasopharyngeal Actinomycosis Masquerading as a Tumour – A Diagnostic Conundrum

Annals of Indian Academy of Neurology ¦ Volume 24 ¦ Issue 4 ¦ July-August 2021 597 Pediatric phantom vision (Charles Bonnet) syndrome. Pediatr Neurol 2002;26:143-5. 3. Menon GJ. Complex visual hallucinations in the visually impaired: A structured history-taking approach. Arch Ophthalmol 2005;123:349-55. 4. Ormond AW. Visual hallucinations in sane people. Br Med J 1925;2:376-9. 5. Charette S. Clinical Vignette. Proceedings of UCLA Health Volume 24, 2020. proceedings.med.ucla.edu [Internet]. University of California: Department of Medicine. [updated 2020 September 21; cited 2021 March 4]. Available from: https://proceedings.med.ucla.edu/index. php/2020/09/21/the-fuzz/. 6. Royal College of General Practitioners (UK). Charles Bonnet Syndrome (CBS) –Visual Hallucinations associated with poor vision. RCGP.org.uk [Internet]. London: Royal College of General Practitioners. [updated 2015 February; cited 2021 March 4]. Available from: https://www.rcgp. org.uk/eyehealth. 7. Yosar J. What is Charles Bonnet syndrome, the eye condition that causes visual hallucinations? medicine.uq. edu.au [Internet]. The University of Queensland: Faculty of Medicine. [updated 2020 August 7; cited 2021 March 4]. Available from: https://medicine.uq. edu.au/article/2020/02/ what-charles-bonnet-syndrome-eye-condition-causes-hallucinations.
3RS initiative in Malaysian public university: A case study of green team, International Islamic University Malaysia

Waste issues have been discussed in every nation. Reports and discussion papers retrieved in developed, developing and third world countries, shows that wastes are common issues and problems. One of the solutions is implementing the Waste Management Hierarchy. The aim of a Waste Management Hierarchy is to minimize the amount of waste from entering the landfill/dump sites. Three top initiatives in the waste management hierarchy is the 3Rs initiative, i.e. Reduce, Reuse and Recycle. As waste management is a subset of environmental management, it can also be a subset of Facilities Management. To cultivate a 3R culture in a society, it is important to train groups of people by creating an awareness programme towards implementing 3Rs initiative. It is essential to start by educating people with knowledge, especially among students in universities. Thus, the aim of this paper is to explore the current stage of 3Rs awareness among university students by using questionnaires and case study approach in the International Islamic University Malaysia. It is also the aim of this paper to suggest methods in creating awareness among students in universities by developing a Waste Minimization Awareness Model (WMAM).
Word Stress in Qassimi Arabic: A Constraint-Based Analysis

This study aimed to produce a formalism of word stress in Qassimi Arabic (QA), which is a sub-dialect of Najdi Arabic (NA), using a constraint-based approach. To this end, this paper investigated two main topics: The first topic explored word stress in QA. Word stress in QA, as well as in NA, is predictable; it can be determined by syllable weight and position. However, two cases do not conform to such straightforward stress rules. These cases are represented by the words: [ʔal. ʕa. sˤir] ‘afternoon’ and [ʔa. ʕa. rif] ‘I know’. Derivational analysis of these exceptions shows the importance of relating the surface structures of such forms to their underlying representations. The second topic aimed to make a formalism for stress patterns in QA using optimality theory (OT). Thus, QA word stress rules and their exceptions are translated into conflicting constraints that are ranked relative to one another by the use of constraint-relation tableaux. This ranking eventually produced the following constraint-relation hierarchy: Lx≈Pr, SYLLABLE-INTEGRITY, TROCHAIC, FAITH-PK >> NONFINAL >> *[ʔa. >> FTBIN-µ, WSP, ALL-FEET-RIGHT >> MAIN-RIGHT, PARSE-σ.
EIC Remarks for a Special 20th Anniversary Issue of MRMS

Magnetic Resonance in Medical Sciences (MRMS), the official journal of the Japanese Society of Magnetic Resonance in Medicine (JSMRM), has reached the milestone of Vol. 20. To celebrate the occasion, we have invited a group of researchers who have made certain outstanding contributions over the years to write a review article for this special 20th anniversary issue. We sincerely thank the authors for their contributions and believe that you will find the reviews informative as they contain a lot about the recent state of the art. For the 20th anniversary, I would like to present here a short history of the journal and talk about some of the major contributors to MRMS over the years. MRMSwas first published in 2002 under the leadership of Professor Kazuro Sugimura, the 1st Editor-in-Chief (EIC). His mission was to create an internationally recognized journal published by JSMRM for all active MR scientists and engineers. At first, MRMS was unfamiliar to people in the field of MR, but under the 2nd EIC, Dr. TsuneyaWatabe, the editorial committee endeavored to raise the profile of the journal. Happily, the number of submissions has gradually increased over time. At about the time Dr. Shigeki Aoki was selected as the 3rd EIC, MRMS succeeded in acquiring an Impact Factor (IF), and from that time, the number of submissions has significantly increased. Although there have been some fluctuations, the IF has been on an upward trend with the most recent value, announced in June 2021, being 2.471 (Fig. 1). We are extremely grateful for the contributions of both the authors who submit important research and the reviewers who volunteer their time to review and comment on those submissions. From here, I would like to introduce some of the major contributions.
Iterative Methods for Polynomial Equations Based on Vieta’s Theorem

Base Vieta’s theorem, iterative methods for polynomial equations are proposed and all roots of polynomial equation can be found simultaneously. The convergence of methods is preliminarily discussed. Examples are given. Introduction In mathematics, a univariate polynomial is an expression of the form 0 0 1 1 1        a x a x a x a n n n n  ( n i R a a Z n j n , , 1 , 0 , , 0 ,       ). The natural number n is known as the degree of the polynomial. A polynomial equation of degree n has exactly n roots. In elementary algebra, methods such as the quadratic formula are given for solving all first degree and second degree polynomial equations in one variable. There are also formulas for the cubic and quadratic equations. For higher degrees, the Abel–Ruffini theorem asserts that there cannot exist a general formula in radicals. However, root-finding algorithms may be used to find numerical approximations of the roots of a polynomial expression of any degree[1-4]. In this paper, the iterative method is used to solve the polynomial equation of any degree based on the Vieta's theorem. A usual iterative method for the polynomial equations can be found one root[5-8], but the method of this paper can be found simultaneously all the roots of the polynomial equation. Vieta's Theorem Vieta's Theorem for polynomial equations says that if a polynomial equation 0 0 1 1 1        a x a x a x a n n n n  ( 0  n a ) has n different roots n x x x , , , 2 1  , then n n n a a x x x 1 2 1        (1) n n n n n a a x x x x x x x x x x x x 2 1 4 2 3 2 1 3 1 2 1            (2) n n n n n n a a x x x x x x x x x x x x x x x x x x 3 1 2 5 3 1 4 3 1 2 1 4 2 1 3 2 1              (3) n n n n a a x x x x x 0 1 3 2 1 ) 1 (    (4) Copyright © 2018, the Authors. Published by Atlantis Press. This is an open access article under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/). 107 8th International Conference on Mechatronics, Computer and Education Informationization (MCEI 2018) Advances in Computer Science Research (ACSR), volume 83