Miracle-dz/UniFAR-FTUs huggingface dataset:
The Differences in Clinical Manifestations and Prognosis of Infective Endocarditis Patients With Positive Serology to Antineutrophilic Cytoplasmic Antibody Compared to Negative Serology

Previous studies have established a relationship between bacterial proteins and autoimmune diseases through several mechanisms. Infective endocarditis is known for its immunological phenomena, and the presence of antineutrophil cytoplasmic antibodies (ANCA) antibodies has been previously demonstrated in several infectious diseases. This retrospective, comparative, and descriptive study examined the relationship between infective endocarditis and the presence of ANCA antibodies. Ninety infective endocarditis cases were included in the study and tested for ANCA antibodies. The prevalence of ANCA positivity was determined, along with the differences in characteristics and prognosis between infective endocarditis patients with positive and negative serology for ANCA antibodies. The results showed that the characteristics of endocarditis patients who underwent ANCA serology testing were similar to those who did not, except for a higher prevalence of central line and chronic kidney disease in patients with ANCA serology (6.7% compared to 1.1% and 25.6% compared to 12.9%, respectively). Of the 90 endocarditis patients tested for ANCA serology, 18% were ANCA-positive, consistent with other prospective studies. There were no statistically significant differences in the primary outcome, six-month and one-year mortality, between patients with positive and negative ANCA serology. Similarly, in the secondary outcomes of acute kidney injury, heart surgery, and days of hospitalization, there were no statistically significant differences between patients with positive and negative ANCA serology. However, there were statistically significant differences in certain characteristics between the two groups. Patients with positive ANCA serology were found to have a higher prevalence of Enterococcus involvement (29.4% compared to 9.6% with P-value 0.046) and Q fever (23.5% compared to 4.1% P-value 0.02%). In contrast, patients with negative ANCA serology had a higher prevalence of fever (73% compared to 41% P-value 0.033).
Breaking Barriers—The Intersection of AI and Assistive Technology in Autism Care: A Narrative Review

(Background) Autism increasingly requires a multidisciplinary approach that can effectively harmonize the realms of diagnosis and therapy, tailoring both to the individual. Assistive technologies (ATs) play an important role in this context and hold significant potential when integrated with artificial intelligence (AI). (Objective) The objective of this study is to analyze the state of integration of AI with ATs in autism through a review. (Methods) A review was conducted on PubMed and Scopus, applying a standard checklist and a qualification process. The outcome reported 22 studies, including 7 reviews. (Key Content and Findings) The results reveal an early yet promising interest in integrating AI into autism assistive technologies. Exciting developments are currently underway at the intersection of AI and robotics, as well as in the creation of wearable automated devices like smart glasses. These innovations offer substantial potential for enhancing communication, interaction, and social engagement for individuals with autism. Presently, researchers are prioritizing innovation over establishing a solid presence within the healthcare domain, where issues such as regulation and acceptance demand increased attention. (Conclusions) As the field continues to evolve, it becomes increasingly clear that AI will play a pivotal role in bridging various domains, and integrated ATs with AI are positioned to act as crucial connectors.
Rapid Assessment of Earthquake Source Characteristics

Recent studies emphasize the rapid assessment of earthquake source properties, such as moment magnitude, to help alleviate the impact of earthquakes. Depending on local crustal structure, earthquakes occurring at different depths can differ greatly in high‐frequency motions, which emphasizes the importance in constraining focal depth for the predictions of strong motions. For large earthquakes, assessing rupture directivity is also essential in estimating ground‐motion effects throughout the source region. In this article, we perform an in‐depth study on a group of recent earthquakes near the intersection of the San Jacinto and San Andreas fault systems in southern California. We develop a systematic method to accurately estimate moment magnitude and focal mechanism within 3–6 s after the first P arrival. Focal depth can also be constrained within ∼10 s upon the arrival of S waves. To determine the direction of fault rupture, we implement a forward‐modeling method, which takes smaller earthquake recordings as empirical Green’s functions to simulate the rupture direction of the beginning motion generated by larger events. With a small event nearby, we resolve the rupture characteristic of the 2014 M_w 4.4 event using information at stations within 35 km from the epicenters and successfully predict the ground‐motion response at stations at farther distances, where directivity effect is significant. Rupture direction of simulated earthquakes with larger magnitudes can also be accurately resolved using the method proposed, opening a possibility to predict ground motions ahead of time, in particular for hazardous regions.
Safe laparoscopic cholecystectomy technique and timing for acute cholecystitis: a study in India

Background: Acute cholecystitis patients undergo laparoscopic cholecystectomy (LC) within 72 hours or 6 weeks to 12 weeks after onset is widely considered the optimal timings for LC. However, there has been no clear consensus about it. We aimed to determine safe technique of LC for acute cholecystitis within 72 hours or any time of presentation with no delay in surgery. Methods: Medical records of 100 patients who underwent standard LC were reviewed retrospectively. Patients were divided into group 1, patients undergoing LC within 72 hours of onset; group 2, between 4 days to 14 days; group3, between 3 weeks to 6 weeks; group 4, more than 6 weeks. Results: No significant differences existed between groups in conversion rate to open surgery, operation time, blood loss, or postoperative morbidity, and hospital stay. However, total hospital stays in groups 1 and 2 was significantly shorter than that in groups 3 and 4 (p<0.01). In addition, the total hospital stay in group 3 was also significantly shorter than that in group 4 (p<0.01). Conclusions: Best timing of LC for acute cholecystitis may be within 72 hours, and there is no need to delay LC in patients presenting after 72 hours and with safe technique of dissecting at infundibulum retrieval of stones and cystic duct stump closure with catgut loop there is no significant difference observed retrospectively.
Comparison of Dental Zirconium Oxide Ceramics Produced Using Additive and Removal Technology for Prosthodontics and Restorative Dentistry—Strength and Surface Tests: An In Vitro Study

Background: The aim of this in vitro study was to determine the mechanical and functional properties of zirconium oxide ceramics made using 3D printing technology and ceramics produced using conventional dental milling machines. Methods: Forty zirconia samples were prepared for this study: the control group consisted of 20 samples made using milling technology, and the test group consisted of 20 samples made using 3D printing technology. Their surface parameters were measured, and then their mechanical parameters were checked and compared. Density, hardness, flexural strength and compressive strength were tested by performing appropriate in vitro tests. After the strength tests, a comparative analysis of the geometric structure of the surfaces of both materials was performed again. Student’s t-test was used to evaluate the results (p < 0.01). Results: Both ceramics show comparable values of mechanical parameters, and the differences are not statistically significant. The geometric structure of the sample surfaces looks very similar. Only minor changes in the structure near the crack were observed in the AM group. Conclusion: Ceramics made using additive technology have similar mechanical and surface parameters to milled zirconium oxide, which is one of the arguments for the introduction of this material into clinical practice. This in vitro study has shown that this ceramic can compete with zirconium made using CAD/CAM (Computer-Aided Design and Computer-Aided Manufacturing) methods.
Simulating and understanding a summertime dry lightning event in coastal California

SIMULATING AND UNDERSTANDING A SUMMERTIME DRY LIGHTNING EVENT IN COASTAL CALIFORNIA by Philip I. Martin Thunderstorms are rare in coastal California during the summer months. Synoptic situations that encourage these summertime thunderstorms typically involve elevated instability that promotes dry lightning thunderstorms, where less than 0.1 in of precipitation reaches the ground. On 21 June 2008, a poorly forecasted dry lightning outbreak was responsible for starting more than 1,500 wildfires across California, and specifically the Monterey region. In this research, we used analysis data from the Global Forecast System (GFS) model to investigate the evolution of the synoptic conditions leading up to the outbreak. We then created two sets of ensembles with the Weather Research and Forecasting (WRF) mesoscale model to determine if dry convection could be simulated in areas where lightning strikes were observed. Two of the WRF-NAM ensemble members showed skill in simulating the Monterey convection. Instability and moisture fields in these simulations were also indicative of dry convection. Graupel behavior was analyzed in these simulations to determine lightning potential following McCaul et al. (2009). Overall, the convection generated by these simulations was found to be robust enough for modest cloud electrification, but recalibration that includes dry convection may be necessary to further improve this method of lightning threat detection.
CATCH CROP (OIL RADISH) FUNCTIONS IN LONG TERM CEREAL CROP ROTATION

The aim of our research work was to study the role of the oil radish catch crop (Raphanus sativus var oleiformis Pers) as second crop or stubble crop for green manuring in winter wheat-winter barley-maize crop rotation. The oil radish was grown after the harvest of winter barley in the crop sequence. The green biomass (t ha -1 ), nitrogen (N) content in dry material (g kg -1 ) of catch crop and the N (kg ha -1 ) taken up by the catch crop were investigated for six years (1997-2002). The main goal was to measure the amount of remained N in the soil left by the main crop (WB) and the amount of N taken up by the oil radish catch crop. The maximum N uptake was about 120 kg ha -1 calculated on the average of the years but in the rainy 1998 the N removal reached the 200 kg ha -1 N. On the basis of the N balance calculation it is proved that incorporation of the catch crop in the crop sequence, the risk of N leaching diminishes, or can be minimal even if the level of N input is high, because the N removal of green biomass retains N in the soil and this way N turnover of the crop rotation remains balanced.
Evaluation of two formulations of progesterone in HeatSynch protocols in lactating Holstein cows in a pasture-based system.

Para evaluar dos formulaciones de progesterona (inyectable: MAD-4, o impregnada en un dispositivo intravaginal: DIV) incluidas en el protocolo de sincronización de celos HeatSynch, se utilizaron 377 vacas Holando en producción, primíparas y multíparas, ciclando y en anestro, ubicadas en tres tambos. El protocolo consistió en: Día 0: GnRH y administración de MAD-4 o DIV; Día 7: Prostaglandina (PG); Día 8: Benzoato de estradiol (BE); Día 9: detección de celo e IA; Día 10: Inseminación Artificial a Tiempo Fijo (IATF) a vacas que no mostraron celo. Se realizó el diagnóstico de gestación mediante ultrasonografía a 45 días del inicio de los tratamientos. Se extrajeron muestras de leche los Días -7 y 0 para determinación de actividad ovárica mediante la dosificación de progesterona. Los porcentajes de preñez a la primera inseminación fueron: 20,5% en el tambo 1, 30,8% en el tambo 2, y 43,3% en el tambo 3 (P<0,05). La fertilidad del tratamiento no fue afectada por la fuente de progesterona (DIV: 33,0, MAD-4: 33,1%; P>0,01) la ciclicidad Evaluación de dos formulaciones de progesterona en protocolos HeatSynch en vacas Holando lactando en sistemas pastoriles
Students’ Perception on Game-Based Learning Using Technology: Kahoot! As a Case Study

There have been studies which exploring students’ perception on the use of kahoot! However, research on investigating students’ opinion on the implementation of kahoot and students’ recommendation for educational stake-holders is uncommon. This study relies on semi-structured interview data from 15 second-year students (10 female and 5 male) enrolling in the Introduction to Linguistics Class in English Education Department of STKIP Yapis Dompu. This study aims to explore the benefits of the use of kahoot, the barriers and students’ recommendation to educational stake-holders for improvement. The data were analysed using thematic analysis adapted from (Braun & Clarke, 2006) which consists of 6 steps. The finding of this paper suggested that the implementation of kahoot in learning process had four benefits: Firstly, Kahoot creates fun and interested learning atmosphere. Secondly, it riggers students’ attention and focus. Thirdly, it facilitates comprehension of material Taught. Lastly, Kahoot! fosters positive competitiveness among students. Additionally; there were two main barriers of using kahoot in this research: firstly, limitations on internet access. Secondly, not enough time to answer. The surprising conclusion of the research was that, all participants had never been exposed to game-based learning platform during their formal school (elementary and high school); they only were only exposed to game-based learning platform at this introduction to linguistics class. Therefore; all participants highly recommended to all lecturers and teachers to game-based learning platform in their teaching. This study relied on game-based learning platform kahoot. Therefore, similar study which explores other game-based learning platforms is highly recommended.
Attitude Towards Humanoid Robots and the Uncanny Valley Hypothesis

Abstract The main aim of the presented study was to check whether the well-established measures concerning the attitude towards humanoid robots are good predictors for the uncanny valley effect. We present a study in which 12 computer rendered humanoid models were presented to our subjects. Their declared comfort level was cross-referenced with the Belief in Human Nature Uniqueness (BHNU) and the Negative Attitudes toward Robots that Display Human Traits (NARHT) scales. Subsequently, there was no evidence of a statistical significance between these scales and the existence of the uncanny valley phenomenon. However, correlations between expected stress level while human-robot interaction and both BHNU, as well as NARHT scales, were found. The study covered also the evaluation of the perceived robots’ characteristic and the emotional response to them.
Paleoenvironmental changes in Southern Patagonia during late Quaternary inferred from lake sediments of Laguna Potrok Aike, Argentina

An investigation of stable isotope (δ 13 CTOC and δ 15 NTN) and elemental parameters (TOC, TN contents and TOC/TN ratios) of bulk organic matter (<200 μm) from sediment cores recovered from the Patagonian lake Laguna Potrok Aike (Argentina) in the framework of the ICDP deep drilling project PASADO provided insights into past changes in lake primary productivity and environmental conditions in South Patagonia throughout the last Glacial – Interglacial transition. Stratigraphically constrained cluster analyses of all proxy parameters suggest four main phases. From ca. 26,100 to 17,300 cal. years BP, lacustrine phytoplankton was presumably the predominant organic matter source in an aquatic environment with low primary productivity rates. At around 17,300 cal. years BP, abrupt and distinct shifts of isotopic and elemental values indicate that the lacustrine system underwent a rapid reorganization. Lake primary productivity (phytoplankton and aquatic macrophytes) shows higher levels albeit with large variations during most of the deglaciation until 13,000 cal. years BP. The main causes for this development can be seen in improved growing conditions for primary producers because of deglacial warming in combination with expedient availability of nutrients and likely calm wind conditions. After 13,000 cal. years BP, decreased δ 13 CTOC values, TOC, TN contents and TOC/TN ratios indicate that the lake approached a new state with reduced primary productivity probably induced by unfavorable growing conditions for primary producers like strengthened winds and reduced nutrient availability. The steady increase in δ 15 NTN values presumably suggests limitation of nitrate supply for growth of primary producers resulting from a nutrient shortage after the preceding phase with high productivity. Nitrate limitation and consequent decreased lacustrine primary productivity continued into the early Holocene (10,970 – 8400 cal. years BP) as reflected by isotopic and elemental values. Chapter 2 Carbon and nitrogen isotope records of bulk organic matter 11
Evaluation of Safety and Probiotic Traits from a Comprehensive Genome-Based In Silico Analysis of Ligilactobacillus salivarius P1CEA3, Isolated from Pigs and Producer of Nisin S

Ligilactobacillus salivarius is an important member of the porcine gastrointestinal tract (GIT). Some L. salivarius strains are considered to have a beneficial effect on the host by exerting different probiotic properties, including the production of antimicrobial peptides which help maintain a healthy gut microbiota. L. salivarius P1CEA3, a porcine isolated strain, was first selected and identified by its antimicrobial activity against a broad range of pathogenic bacteria due to the production of the novel bacteriocin nisin S. The assembled L. salivarius P1CEA3 genome includes a circular chromosome, a megaplasmid (pMP1CEA3) encoding the nisin S gene cluster, and two small plasmids. A comprehensive genome-based in silico analysis of the L. salivarius P1CEA3 genome reveals the presence of genes related to probiotic features such as bacteriocin synthesis, regulation and production, adhesion and aggregation, the production of lactic acid, amino acids metabolism, vitamin biosynthesis, and tolerance to temperature, acid, bile salts and osmotic and oxidative stress. Furthermore, the strain is absent of risk-related genes for acquired antibiotic resistance traits, virulence factors, toxic metabolites and detrimental metabolic or enzymatic activities. Resistance to common antibiotics and gelatinase and hemolytic activities have been discarded by in vitro experiments. This study identifies several probiotic and safety traits of L. salivarius P1CEA3 and suggests its potential as a promising probiotic in swine production.
Value-based framing in Russian propaganda on the example of the war against Ukraine and its consequences

The paper discusses the issue of Russian propaganda and common value’s place in it. According to theoretical framework, the article is focused on framing in Kremlin’s rhetoric as a whole, since Kremlin is controlling the media. Value manipulation in 20st century is briefly discussed and follows by analysis of Kremlin rhetoric is on the example of the war in Ukraine, defining a number of value-based frames used to shape the public opinion and examining them. The paper also addresses the possible consequences of such rhetoric and the analysis leads to the conclusion that Russia are appealing to common values in its propaganda and is hereby threatening these values both domestically and internationally, and hiding unlawful nature of its politics.
Some important aspects in Moringa oleifera Lam. micropropagation

Type and source of explant as well as the type of cytokinin were important factors for successful moringa micropropagation. Explants obtained from in vitro grown plant materials were better than others obtained from soil growing seedlings. In addition, nodal segments were better than shoot cuttings in terms of number of shoots/ explants, frequency of shoot formation and number of nodes/shoot. While callus formation on the base of nodal segment on BAP containing media were higher than those of KIN, especially under the influence of high concentration as an aspect of vitrification, BAP was better than KIN in moringa multiplication. Low nutrient medium (half strength MS) supplemented with 0.5 mg l-1 IAA was essential for successful root formation. The suitable conditions for moringa micropropagation on full strength MS or SH may exert low stress and low need to raise the expression of SOD and POX. On the other side, stress due to over increase of chemical components of double MS medium or low nutrient content of half strength MS, B5 or WPM expressed the highest number and staining intensity of SOD and POX bands, vice versa was detected in case of CAT.
Formación del futuro profesorado de educación secundaria en pensamiento histórico: análisis de niveles y discursos

Este artículo aborda los niveles de formación del futuro profesorado de educación secundaria en pensamiento histórico y sus discursos al respecto. Se analiza un ejercicio escrito sobre conocimiento y aplicación de competencias de pensamiento histórico realizado por 156 docentes de historia en formación, estudiantes del Máster de Profesor/a de Educación Secundaria (MAES) de la Universidad de Valencia entre 2019 y 2022. El ejercicio demanda el análisis argumentado de un examen real de educación secundaria basado en dicho enfoque: se examina la capacidad y niveles para reconocer competencias históricas, explicar cómo se usan y diseñar una rúbrica para su evaluación. A través de un análisis cualitativo de las respuestas basado en la teoría fundamentada se categorizan niveles formativos al respecto (nulo, declarativo y aplicativo) poniéndolos en relación con sus discursos sobre modelos curriculares o didácticos práctico y crítico y con la innovación educativa en la enseñanza de la historia. Se confirma que en diferentes cursos y contextos formativos, la mayoría del futuro profesorado manifiesta niveles declarativos como conocimiento disciplinar del contenido; sólo una minoría dispone de niveles más complejos de aplicación o conocimiento pedagógico del contenido. Los participantes con niveles aplicativos son, mayoritariamente, quienes han aprovechado mejor el MAES: tanto su formación teórica, llegando a una visión crítica sobre los contenidos y usos de la historia escolar y la innovación educativa, por encima de una mera visión metodológica; como sus prácticas educativas, argumentando las dificultades del enfoque de pensamiento histórico en las aulas.