Miracle-dz/UniFAR-FTUs huggingface dataset:
Proactive Effect of Algae-Based Graphene Support on the Oxygen Evolution Reaction Electrocatalytic Activity of NiFe

The preparation of graphene materials from biomass resources is still a challenge, even more so if they are going to be employed as supports for electrocatalysts for water splitting. Herein, we describe the preparation and characterization of graphene oxides (GOs) from solid macroalgae waste obtained after processing an agar–agar residue. The structural and morphological characterization of the obtained GO confirm the presence of a lamellar material that is composed of few layers with an increased number of heteroatoms (including nitrogen) if compared with those observed in a GO obtained from graphite (reference). Three-dimensional electrodes were prepared from these GOs by depositing them onto a fibrous carbon paper, followed by electrodeposition of the catalyst, NiFe. The electrocatalytic performance of these hybrid systems for the oxygen evolution reaction (OER) showed a proactive effect of both graphene materials toward catalysis. Moreover, the electrode prepared from the algae-based graphene showed the highest electrocatalytic activity. This fact could be explained by the different structure of the algae-based graphene which, due to differences in the nucleation growth patterns and electroactive sites developed during the electrodeposition process, produced more reactive NiFe species (higher oxidation state).
The High-Resolution SAR Image Terrain Classification Algorithm Based on Mixed Double Hint Layers RBFN Model

The research on the high-resolution synthetic aperture radar(SAR) image automatic terrain classification (ATC) is made.Firstly,the shortage of the traditional feed-forward neural network model in SAR image classification is concluded.Then a new model named mixed double hint layers RBFN (MDHRBFN) is presented,which combines radial basis function network(RBFN) with mixed expert system.Finally,an algorithm based on this model for the high-resolution,single-look and single-polarization SAR images terrain classification is given and evaluated.The results show that this algorithm can readily cluster the SAR image into man-made targets,natural target,background and shadow,and has better performance than the one based on RBFN model.It can not only be applied to SAR image assistant interpretation,but also offer the potential target chips for target recognition process.
Risk Factors of Postoperative Acute Pancreatitis and Its Impact on the Postoperative Course after Pancreaticoduodenectomy—10 Years of Single-Center Experience

Background: Clinically relevant acute postoperative pancreatitis (CR-PPAP) after pancreaticoduodenectomy (PD) is a complication that may lead to the development of local and systemic consequences. The study aimed to identify risk factors for CR-PPAP and assess the impact of CR-PPAP on the postoperative course after PD. Methods: The study retrospectively analyzed data from 428 consecutive patients who underwent PD at a single center between January 2013 and December 2022. The presence of increased amylase activity in plasma, above the upper limit of normal 48 h after surgery, was checked. CR-PPAP was diagnosed when accompanied by disturbing radiological features and/or symptoms requiring treatment. We investigated the relationship between the occurrence of CR-PPAP and the development of postoperative complications after PD, and possible predictors of CR-PPAP. Results: The postoperative follow-up period was 90 days. Of the 428 patients, 18.2% (n = 78) had CR-PPAP. It was associated with increased rates of CR-POPF, delayed gastric emptying, occurrence of intra-abdominal collections, postoperative hemorrhage, peritonitis, and septic shock. Patients who developed CR-PPAP were more often reoperated (37.17% vs. 6.9%, p < 0.0001)) and had increased postoperative mortality (14.1% vs. 5.74%, p < 0.0001). Soft pancreatic parenchyma, intraoperative blood loss, small diameter of the pancreatic duct, and diagnosis of adenocarcinoma papillae Vateri were independent risk factors for CR-PPAP and showed the best performance in predicting CR-PPAP. Conclusions: CR-PPAP is associated with an increased incidence of postoperative complications after PD, worse treatment outcomes, and an increased risk of reoperation and mortality. Pancreatic consistency, intraoperative blood loss, width of the duct of Wirsung, and histopathological diagnosis can be used to assess the risk of CR-PPAP. Amylase activity 48 h after surgery > 161 U/L is highly specific in the diagnosis of CR-PPAP.
Exact Analytical Relations for the Average Release Time in Diffusional Drug Release

Although analytical solutions for the problem of diffusion-controlled drug release from uniform formulations of simple geometries, like slabs, spheres, or cylinders, are well known, corresponding exact expressions for the average release times are not widely used. However, such exact analytical formulae are very simple and useful. When the drug is initially distributed homogeneously within the matrix, the average time of release from a sphere of radius R is tav=(1/15)R2/D and from a slab of thickness L is tav=(1/12)L2/D, where D is the corresponding drug diffusion coefficient. Regarding cylindrical tablets of height H and radius R, simple analytical expressions are obtained in the two opposite limits of either very long (H≫R) or very short (H≪R) cylinders. In the former case, of practically radial release, the average release time is tav=(1/8)R2/D, while in the latter case the same result as that of a slab with thickness H is recovered, tav=(1/12)H2/D, as expected. These simple and exact relations are useful not only for an estimate of the average release time from a drug carrier device when diffusion is the dominant mechanism of drug delivery, but also for the experimental determination of the drug diffusion coefficient in a release system of interest through the measured release profile, given the mean squared size of the formulation.
Improving Cognitive Function with Nutritional Supplements in Aging: A Comprehensive Narrative Review of Clinical Studies Investigating the Effects of Vitamins, Minerals, Antioxidants, and Other Dietary Supplements

Cognitive impairment and dementia are burgeoning public health concerns, especially given the increasing longevity of the global population. These conditions not only affect the quality of life of individuals and their families, but also pose significant economic burdens on healthcare systems. In this context, our comprehensive narrative review critically examines the role of nutritional supplements in mitigating cognitive decline. Amidst growing interest in non-pharmacological interventions for cognitive enhancement, this review delves into the efficacy of vitamins, minerals, antioxidants, and other dietary supplements. Through a systematic evaluation of randomized controlled trials, observational studies, and meta-analysis, this review focuses on outcomes such as memory enhancement, attention improvement, executive function support, and neuroprotection. The findings suggest a complex interplay between nutritional supplementation and cognitive health, with some supplements showing promising results and others displaying limited or context-dependent effectiveness. The review highlights the importance of dosage, bioavailability, and individual differences in response to supplementation. Additionally, it addresses safety concerns and potential interactions with conventional treatments. By providing a clear overview of current scientific knowledge, this review aims to guide healthcare professionals and researchers in making informed decisions about the use of nutritional supplements for cognitive health.
Controlled Plasma Membrane Delivery of FGFR1 and Modulation of Signaling by a Novel Regulated Anterograde RTK Transport Pathway

Simple Summary Fibroblast Growth Factor Receptor-1 (FGFR1), a major receptor tyrosine kinase (RTK), regulates early embryonic development and organogenesis. However, overexpression of FGFR1 is seen in many human solid tumors and is associated with poor prognosis, resistance to multiple therapies and aggressive metastatic spread. Our aim was to study the mechanisms controlling FGFR1 activity, with an ultimate goal of identifying key therapeutic targets for solid tumors. We unexpectedly found that a major splice variant, FGFR1 IIIc, was sequestered in intracellular vesicles under normal conditions. We investigated this phenomenon in detail to identify the sequestration mechanism and further elucidated how the sequestration was released to permit receptor translocation to the plasma membrane (PM) in response to microenvironmental cues. The novel pathway, a first such mechanism identified for RTK, regulates PM localization of FGFR1 IIIc, thereby determining its signal output. This knowledge will aid in the development of next-generation strategies to silence FGFR1 in solid tumors. Abstract How human FGFR1 localizes to the PM is unknown. Currently, it is assumed that newly synthesized FGFR1 is continuously delivered to the PM. However, evidence indicates that FGFR1 is mostly sequestered in intracellular post-Golgi vesicles (PGVs) under normal conditions. In this report, live-cell imaging and total internal reflection fluorescence microscopy (TIRFM) were employed to study the dynamics of these FGFR1-positive vesicles. We designed recombinant proteins to target different transport components to and from the FGFR1 vesicles. Mouse embryoid bodies (mEBs) were used as a 3D model system to confirm major findings. Briefly, we found that Rab2a, Rab6a, Rab8a, RalA and caveolins are integral components of FGFR1-positive vesicles, representing a novel compartment. While intracellular sequestration prevented FGFR1 activation, serum starvation and hypoxia stimulated PM localization of FGFR1. Under these conditions, FGFR1 C-terminus acts as a scaffold to assemble proteins to (i) inactivate Rab2a and release sequestration, and (ii) assemble Rab6a for localized activation of Rab8a and RalA-exocyst to deliver the receptor to the PM. This novel pathway is named Regulated Anterograde RTK Transport (RART). This is the first instance of RTK regulated through control of PM delivery.
Assessment of pollen quality and quantity in White and Black Turkish Myrtus communis L. accessions, through In Vitro pollen germination under varied boric acid concentrations

This study aimed to evaluate the pollen properties, pollen viability and germination with suitable germination medium and amount of pollen production in 6 Turkish myrtle genotypes. The genotypes were evaluated as their origin and fruit colours in terms of 3 different origins (Erdemli, Karaisali and Tarsus) and 2 fruit colours (black and white). Results showed that, pollen properties were affected from fruit colours and black genotypes generally showed higher pollen properties. The amount of pollen production of one flower was very high ranging from 2.5 to 4.5 million. Pollen viability and germination rates showed sufficient results for successful pollination in Turkish myrtle genotypes. Among pollen germination media, the best pollen germination rate was obtained from 50 ppm boric acid. Consequently, this study identified the pollen performance of white and black Turkish myrtle genotypes and suggested an optimal pollen germination medium for Myrtus communis which can be used in the future breeding programmes.
Five new species of Alisotrichia Flint, 1964 (Trichoptera: Hydroptilidae: Leucotrichiinae) from Northeastern Brazil

Five new species of Alisotrichia Flint, 1964 microcaddisflies are described and illustrated from type material collected in Northeastern Brazil, constituting the first records of the genus to this region, as it was previously known only from Southeastern and Northern Brazil. The number of Brazilian species of Alisotrichia is doubled herein from five to ten, however, likely there are still many other species to be described. The new species described here are all placed in the orophila species group: A. froehlichi sp. nov. (Sergipe State), A. calori sp. nov. (Bahia and Paraíba states), A. penispinata sp. nov. (Ceará and Pernambuco states), A. dilatata sp. nov. (Ceará and Mato Grosso do Sul states), and A. nordestina sp. nov. (Ceará and Sergipe states). These new species are separated mainly by features of male genitalia, particularly the dorsal area of segment X, the shape of the segment VIII, and the phallus morphology. Currently, the orophila species group is composed by 37 species, more than half of the species diversity of Alisotrichia.
Health effects of indoor nitrogen dioxide

Rationale: Exposure to indoor NO2 has been implicated as a cause of respiratory symptoms suggestive of asthma but evidence has been inconsistent. Objective: To review the existing evidence and examine the effects of indoor NO2 in adult asthma-related symptoms using data from an adult multi-centre cohort (ECRHS) followed up for 20 years. Methods: Studies on respiratory health and indoor NO2 were systematically reviewed and metaanalyses performed. Cross-sectional analyses within a sub-set of ECRHS participants with indoor NO2 measurements were conducted to assess the associations of asthma severity and wheeze prevalence with NO2. A regression model was developed to predict indoor NO2 for a larger ECRHS sample without indoor NO2 measurements. GEE analyses were conducted to examine the long-term effects of gas cooking and modelled indoor NO2 on wheeze and asthma score. To investigate the effect of gas-generating NO2 peaks on asthma exacerbation a panel study was also piloted using a new-to-market portable NO2 sensor. Main results: The systematic review identified 50 studies, mainly in children. Results of metaanalyses suggested a significant association between 12-month period prevalence of wheeze and indoor NO2. Within ECRHS prevalence of wheeze but not asthma severity was associated with measured indoor NO2. Long-term associations of asthma-related symptoms with predicted indoor NO2 exposure but not gas cooking were significant. Interpreting this is difficult as the latter analyses (gas cooking) included a larger number of centres and some heterogeneity across centres was observed in the analysis on asthma score. Gas appliances, outdoor NO2, monthly temperature and country were the main predictors of indoor NO2. Evaluation of the pilot study recommends better recruitment strategies and independent calibration of NO2 sensor. Conclusions: There is some evidence for a link between indoor NO2 and asthma-related symptoms. Health risks may be small but are applied to a substantial proportion of the population.
A Review of the Utilization of Canola Protein as an Emulsifier in the Development of Food Emulsions

Canola is the second-largest cultivated oilseed crop in the world and produces meal consisting of about 35–40% proteins. Despite this, less than 1% of the global plant-based protein market is taken up by canola protein. The reason behind such underutilization of canola protein and its rapeseed counterpart could be the harsh conditions of the industrial oil extraction process, the dark colour of the meal, the presence of various antinutrients, the variability in the protein composition based on the source, and the different properties of the two major protein components. Although academic research has shown immense potential for the use of canola protein and its rapeseed counterpart in emulsion development and stabilization, there is still a vast knowledge gap in efficiently utilizing canola proteins as an effective emulsifier in the development of various emulsion-based foods and beverages. In this context, this review paper summarizes the last 15 years of research on canola and rapeseed proteins as food emulsifiers. It discusses the protein extraction methods, modifications made to improve emulsification, emulsion composition, preparation protocols, and emulsion stability results. The need for further improvement in the scope of the research and reducing the knowledge gap is also highlighted, which could be useful for the food industry to rationally select canola proteins and optimize the processing parameters to obtain products with desirable attributes.
Predicted Future Forest- and Farmland Development in Western Oregon With and Without Land Use Zoning in Effect

Oregon’s Land Use Planning Program is often cited as an exemplary approach to protecting forest and farm lands from development. In November 2004, Oregon voters approved a ballot measure—Measure 37—to require the state to compensate landowners for any property value losses resulting from land use regulations, including those adopted under the program. Because compensation is viewed by many land use planners and policymakers in the state as virtually impossible because of the potential expense involved, the passage of Measure 37 has placed the continued enforcement of land use regulations into question. A key question for land use planners and policymakers in Oregon, and other states aspiring to implement land use planning programs like Oregon’s, is what effect potential lapses in zoning enforcement might have on forestand farmland development. This research note uses an existing spatial land use model created for western Oregon to predict future development of forest and agricultural lands for two scenarios: (1) one assuming that land use zones adopted under Oregon’s Land Use Planning Program remain unaffected by Measure 37, and (2) one assuming that land use zones are made completely unenforceable by Measure 37. Although neither scenario probably is likely, the predictions suggest a set of bounds defining a range of new development possibilities enabled by pending changes in zoning enforcement resulting from Measure 37. The predictions suggest that a hypothetical lapse of land 1 Jeffrey D. Kline is a research forester, Forestry Sciences Laboratory, 3200 SW Jefferson Way, Corvallis, OR 97331. PNW-RN-548.indd 1 6/6/05 8:59:51 PM 2 RESEARCH PAPER PNW-RN-548 use zoning enforcement beginning in 2004 would result in greater numbers of new buildings on forest and agricultural lands in western Oregon through 2024, more than would have occurred with pre-Measure 37 zoning enforcement. Several caveats are noted in the “Conclusions. ”
SOC Estimation of Li-ion Battery using on Variational Mode Decomposition and Transformer-Generative Adversarial Network

Accurate estimation of the state of charge (SOC) of lithium battery is crucial to improve the dynamic performance and energy utilization of batteries. The method, the existing neural network are used to estimate SOC, has the problems of low accuracy and poor stability under complex working conditions. A new algorithm are proposed to estimate the SOC, which combines Transformer and Generative Adversarial Network (GAN), and the Variational Modal Decomposition (VMD). Firstly, as the excellent prediction ability of Transformer, Transformer is used as the generative network of GAN. Secondly, VMD is used to decompose the SOC historical data into six subsets to increase the input features. Finally, DST work data from the University of Maryland CALCE dataset is used for model training, and the VMD-Transformer-GAN algorithm is compared with LSTM, GRU, and BiLSTM algorithms for experiments. The experimental results show that the VMD-Transformer-GAN algorithm algorithmic estimation model has high stability and accuracy, which verifies the feasibility of the improved scheme.
Hopf Bifurcation and Control for the Bioeconomic Predator–Prey Model with Square Root Functional Response and Nonlinear Prey Harvesting

In this essay, we introduce a bioeconomic predator–prey model which incorporates the square root functional response and nonlinear prey harvesting. Due to the introduction of nonlinear prey harvesting, the model demonstrates intricate dynamic behaviors in the predator–prey plane. Economic profit serves as a bifurcation parameter for the system. The stability and Hopf bifurcation of the model are discussed through normal forms and bifurcation theory. These results reveal richer dynamic features of the bioeconomic predator–prey model which incorporates the square root functional response and nonlinear prey harvesting, and provides guidance for realistic harvesting. A feedback controller is introduced in this paper to move the system from instability to stability. Moreover, we discuss the biological implications and interpretations of the findings. Finally, the results are validated by numerical simulations.
Navigating the landscape: Roles, perspectives, and experiences of psychologists supporting gender diverse children and young people in school settings

Abstract Purpose This review aimed to explore and synthesize the perspectives and experiences of school-based psychological professionals providing support to gender diverse CYP across the world, to foreground the voices of those with relevant experience and support future practice. Methods A systematic review of five databases (PsychINFO, CINAHL, ERIC, SCOPUS and PROQUEST dissertations and theses) was performed between September and November 2022. Articles were included if they contained qualitative, primary research data representing the voice of at least one school-based psychological professional with experience working with gender diverse children and young people. Articles were excluded if they did not contain primary research data, were quantitative, related to non-school based psychologists or focussed on participant views in the absence of direct experience working with gender diverse pupils. Articles were thematically summarized and organized into a data extraction table. Results Eighteen studies were identified for review, including 11 studies based in the USA, five in the UK, one in Australia and one in Cyprus. The voices of school-based professionals, including school counselors, school psychologists, trainee and qualified educational psychologists, were represented. The themes created highlighted the importance of the environment in which psychologists were working, the reliance on their own views and values to guide their work in the absence of clear guidance, the role psychologists saw they had to advocate for gender diverse CYP, as well as barriers and systems they were fighting against. Conclusion The review highlighted the need for psychologists to advocate for gender diverse children and young people, in an often non-inclusive environment where there was a need to work systemically with schools. Future research is needed to explore young people’s experiences of the support that they are receiving and would like to receive.