Miracle-dz/UniFAR-FTUs huggingface dataset:
DigitalCommons@University of Nebraska - Lincoln DigitalCommons@University of Nebraska - Lincoln Spotted owls and forest fire: Comment Spotted owls and forest fire: Comment

Part of the Natural Resources and Conservation Commons, Natural Resources Management and Policy Commons, Other Environmental Sciences Commons, Other Veterinary Medicine Commons, Population Biology Commons, Terrestrial and Aquatic Ecology Commons, Veterinary Infectious Diseases Commons, Veterinary Microbiology and Immunobiology Commons, Veterinary Preventive Medicine, Epidemiology, and Public Health Commons, and the Zoology Commons
Identiﬁcation of Cytokeratin 18 as a Biomarker of Mouse and Human Hepatosplenic Schistosomiasis (cid:1) †

Previously, we demonstrated unique protein expression patterns in 20-week- Schistosoma mansoni -infected CBA/J mice with moderate splenomegaly syndrome (MSS) or hypersplemomegaly syndrome (HSS). To better understand the development of severe pathology, we compared the two-dimensional differential in-gel electrophoresis (2D-DIGE) proteomic signatures of livers from uninfected mice and mice infected for 6, 8, 12, or 20 weeks and found signiﬁcant changes in collagen isoforms, interleukin-2 (IL-2), cytokeratin 18, hydroxyproline, S. mansoni phosphoenolpyruvate carboxykinase, major urinary protein isoforms, and peroxiredoxin 6. Cytokeratin 18, hydroxyproline, and connective tissue growth factor (CTGF) were chosen for analysis in mouse and human sera using targeted biochemical assays. Consistent with the liver analysis, cytokeratin 18, CTGF, and hydroxyproline were signiﬁcantly elevated in sera from mice with HSS compared to those from uninfected mice or mice with MSS. Moreover, cytokeratin 18 and CTGF were found to be markers for subjects with hepatosplenic and intestinal schistosomiasis, respectively, while serum hydroxyproline was a strong indicator of ﬁbrosis for severe HS. These ﬁndings indicate that schistosome-associated changes to the liver can be detected in the serum and reveal the potential for cytokeratin 18 to be used as a diagnostic marker for early detection of hepatosplenic schistosomiasis.
Jbabdi, Saad and Sotiropoulos, Stamatios N. and Haber, Suzanne N. and Van Essen, David C. and Behrens, Timothy E. (2015) Measuring macroscopic brain

Decades of detailed anatomical tracer studies in non-human animals point to a rich and complex organisation of long-range white matter connections in the brain. Stateof-the art in vivo imaging techniques are striving to achieve a similar level of detail in humans, but multiple technical factors can limit their sensitivity and fidelity. In this review we mostly focus on magnetic resonance imaging of the brain. We highlight some of the key challenges in analyzing and interpreting in vivo connectomics data, particularly in relation to what is known from classical neuroanatomy in laboratory animals. We further illustrate that, despite the challenges, in vivo imaging methods can be very powerful and provide information on connections that is not available by any other means.
An intermediate-conductance Ca 2 (cid:1) -activated K (cid:1) channel is important for secretion in pancreatic duct cells

An intermediate-conductance Ca 2 (cid:1) -activated K (cid:1) channel is important for secretion in pancreatic duct cells. Am Physiol 303: C151–C159, 2012. Potassium channels play a vital role in maintaining the membrane potential and the driving force for anion secretion in epithelia. In pancreatic ducts, which secrete bicarbonate-rich ﬂuid, the identity of K (cid:1) channels has not been extensively investigated. In this study, we investigated the molecular basis of functional K (cid:1) channels in rodent and human pancreatic ducts (Capan-1, PANC-1, and CFPAC-1) using molecular and electrophysiological techniques. RT-PCR analysis revealed mRNAs for KCNQ1 , KCNH2 , KCNH5 , KCNT1 , and KCNT2 , as well as KCNN4 coding for the following channels: KVLQT1; HERG; EAG2; Slack; Slick; and an intermediate-conductance Ca 2 (cid:1) activated K (cid:1) (IK) channel (K Ca 3.1). The following functional studies were focused on the IK channel. 5,6-Dichloro-1-ethyl-1,3-dihydro-2 H -benzimidazole-2-one (DC-EBIO), an activator of IK channel, increased equivalent short-circuit current ( I sc ) in Capan-1 monolayer, consistent with a secretory response. Clotrimazole, a blocker of IK channel, inhibited I sc . IK channel blockers depolarized the membrane potential of cells in microperfused ducts dissected from rodent pancreas. Cell-attached patch-clamp single-channel recordings revealed IK channels with an average conductance of 80 pS in freshly isolated rodent duct cells. These results indicated that the IK channels may, at least in part, be involved in setting the resting membrane potential. Furthermore, the IK channels are involved in anion and potassium transport in stimulated pancreatic ducts.
Dewatering of Cellulose Nano brils using Ultrasound

9 Although cellulose nanomaterials have promising properties and performance in a wide 10 application space, one hinderance to their wide scale industrial application has been associated 11 with their economics of dewatering and drying and the ability to redisperse them back into 12 suspension without introducing agglomerates or lose of yield. The present work investigates the 13 dewatering of aqueous suspensions of cellulose nanofibrils (CNF) using ultrasound as a potentially 14 low-cost, non-thermal, and scalable alternative to traditional heat-based drying methods such as 15 spray drying. Specifically, we use vibrating mesh transducers to develop a direct-contact mode 16 ultrasonic dewatering platform to remove water from CNF suspensions in a continuous manner. 17 We demonstrate that the degree of dewatering is modulated by the number of transducers, their 18 spatial configuration, and the flow rate of the CNF suspension. Water removal of up to 72 wt. % is 19 achieved, corresponding to a final CNF concentration of 11 wt. % in 30 minutes using a two20 transducer configuration. To evaluate the redispersibility of the dewatered CNF material, we use 21 a microscopic analysis to quantify the morphology of the redispersed CNF suspension. By 22 developing a custom software pipeline to automate image analysis, we compare the histograms of 23 the dimensions (length, width) of the redispersed dewatered fibrils with the original CNF samples 24 and observe no significant difference, suggesting that no agglomeration is induced due to 25 ultrasonic dewatering. We estimate that this ultrasound dewatering technique is also energy26 efficient, consuming up to 36% less energy than the enthalpy of evaporation per kilogram of water. 27 Together with the inexpensive cost of transducers (<$1), the potential for scaling up in parallel 28 flow configurations, and excellent redispersion of the dewatered CNF, our work offers a proof-of29 concept of a sustainable CNF dewatering system, that addresses the shortcomings of existing 30 techniques. 31
Foreign An Empirical Analysis

Recent work on foreign direct investment has emphasized the weight of political factors in explaining variation across countries. While the aspects of democracies that make them more or less favorable to FDI have been studied and identified, we know less about what differentiates investment levels among authoritarian regimes. In this paper, I seek to unpack variation in FDI flows among such regimes by distinguishing different types of autocracies. I argue that regimes convey different signals regarding political risk to potential foreign investors via both institutional attributes and forms of exercising authority. Specifically, I expect regimes ruled by a collective body, such as military and single-party regimes, to be less volatile and more predictable in their decision-making due to the presence of several actors with veto power. In addition, I also expect regimes with predictable succession rules to transmit lower levels of risk to foreign investors due to the smaller probability of a destabilizing process of leadership turnover. I test these expectations using a time-series cross-sectional data set containing economic, political, and social information from 104 countries over the period 1980-2010, and find support for the veto hypothesis but not for the leadership succession one.
Program for Education and Enrichment of Relational Skills: Program for Education and Enrichment of Relational Skills: Parental Outcomes with an ADHD Sample Parental Outcomes with an ADHD Sample

The goal of the current study was to examine the effect of PEERS®, a 14-week parent-assisted friendship-building program for adolescents with ADHD, on parental functioning, quality of the parent-adolescent relationship, and family functioning. Participants included 25 parents (19 mothers, 6 fathers) of adolescents with ADHD. Families completed the Program for the Education and Enrichment of Relational Skills (PEERS®; Laugeson & Frankel, 2010). Measures of parenting stress, parental efficacy, parent-adolescent communication, parent-adolescent involvement, causal attributions for negative social interactions, and family chaos were completed by parents at pre and post-treatment. Parents demonstrated statistically significant improvements in parenting stress and parent-adolescent communication and marginally statistically significant improvement in parental efficacy. Parents also demonstrated statistically reliable change in measures of parenting stress, parent-adolescent communication, parent-adolescent involvement, and family chaos. Overall, these findings demonstrate the benefit of PEERS® at improving parental functioning, quality of the parent-adolescent relationship, and family functioning for families of adolescents with ADHD.
MICROBIOLOGY Prevalence of mupirocin resistant ( mupA ) gene in S. aureus isolates from two tertiary care hospitals of Punjab

Introduction: Mupirocin is a topical ointment and de-colonizing agent, used to reduce the burden of Staphylococcus aureus from nasal nares. Unjudiciary use of mupirocin has resulted in the emergence of resistance mediated by a gene mupA found to be associated with high-level mupirocin (HLMup R) resistance. The objectives of this study were to find out the prevalence of MRSA/MSSA, mupA gene, and antimicrobial resistance among burn patients and outdoor patients. Material and Methods: A total of 238 non-repetitive specimens were collected from nasal nares and burn wounds of patients in two tertiary care hospitals. S. aureus was isolated by conventional biochemical and molecular methods. Prevalence of resistance gene and antimicrobial susceptibility were identified by PCR and Kirby Bauer disk diffusion method respectively. Results: The prevalence of MRSA was 13% (32/238) and MSS 29% (70/238). We screened 102 isolates for the mupA gene and found 21 MRSA and 12 MSSA with a total of 33 isolates carrying this gene and the p-value was 0.0001. Most strains were found to be MDR. Discussion and Conclusion: MRSA strains are prevailing in hospital environments whereas mupA gene carriage rate shows that antimicrobial use of mupirocin to decolonize bacteria needs to be minimized. Antimicrobial stewardship and closed surveillance may be regulated.
Mwalabu, Gertrude and Evans, Catrin and Redsell, Sarah (2017) Factors influencing the experience of sexual and reproductive healthcare for female adolescents with perinatally-acquired HIV: a qualitative

Background: Young people living with perinatally-acquired HIV require age-appropriate support regarding sex and relationships as they progress towards adulthood. HIV affects both genders but evidence suggests that young women are particularly vulnerable to sexual abuse and more prone to engaging in sexual behaviours to meet their daily survival needs. This can result in poor sexual and reproductive health (SRH) outcomes. HIV services in Malawi provide support for young women’s HIV-related clinical needs, but it is unclear whether there is sufficient provision for their SRH needs as they become adults. This paper explores the sex and relationship experiences of young women growing up with perinatally-acquired HIV in order to understand how to improve SRH care and associated outcomes. Methods: A qualitative case study approach was adopted in which each ‘case’ comprised a young woman (15–19 years) with perinatally acquired HIV, a nominated caregiver and service provider. Participants were purposively selected from three multidisciplinary centres providing specialised paediatric/adolescent HIV care in Malawi. Data was collected for 14 cases through in-depth interviews (i.e. a total of 42 participants) and analysed using within-case and cross-case approaches. The interviews with adolescents were based on an innovative visual method known as ‘my story book’ which encouraged open discussion on sensitive topics. Results: Young women reported becoming sexually active at an early age for different reasons. Some sought a sense of intimacy, love, acceptance and belonging in these relationships, noting that they lacked this at home and/or within their peer groups. For others, their sexual activity was more functional – related to meeting survival needs. Young women reported having little control over negotiating safer sex or contraception. Their priority was preventing unwanted pregnancies yet several of the sample already had babies, and transfer to antenatal services created major disruptions in their HIV care. In contrast, caregivers and nurses regarded sexual activity from a clinical perspective, fearing onward transmission of HIV and advocating abstinence or condoms where possible. In addition, a cultural silence rooted in dominant religious and traditional norms closed down possibilities for discussion about sexual matters and prevented young women from accessing contraception. Conclusion: The study has shown how young women, caregivers and service providers have contrasting perspectives and priorities around SRH care. Illumination of these differences highlights a need for service improvement. It is suggested that young women themselves are involved in future service improvement initiatives to encourage the development of culturally and socially acceptable pathways of care.
DMSO_A_268146 3337..3348

1Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah 21589, Saudi Arabia; 2Cancer Metabolism and Epigenetic Unit, Faculty of Science, King Abdulaziz University, Jeddah 21589, Saudi Arabia Background: Urolithins are gut microbiota-derived polyphenol metabolites, produced following the consumption of pomegranate, berries, and nuts. Recent studies have shown the potentials of these metabolites on reducing triglycerides accumulation in cultured hepatocytes and adipocytes. In this study, we investigated the ability of both urolithin A (Uro-A) and urolithin B (UroB) to attenuate obesity and associated symptoms in a high-fat diet-induced obesity model in rats. Methods: Twenty-four male Wistar rats were randomly assigned to four groups. Group 1 was fed on a normal diet while groups 2, 3, and 4 were fed on a high-fat diet for 10 weeks. After this, groups 3 and 4 were treated with 2.5mg/kg body weight of Uro-A and Uro-B intraperitoneally, respectively. Body weight, serum lipid profile, hepatic antioxidant activity, hepatic lipid accumulation, fecal lipid content, and the expressions of genes involved in lipogenesis and hepatic ER stress were quantified. Results: Indeed, a high-fat diet resulted in increased body weight, visceral adipose tissue mass, and oxidative stress in rats. However, treatment with both Uro-A and Uro-B decreased body weight and visceral adipose tissue mass. These metabolites restored hepatic antioxidant capacity and decreased lipid accumulation in addition to an increase in fecal fat excretion. Moreover, both Uro-A and Uro-B treatment downregulated the expression of LXRα and SREBP1c; involved in de novo lipogenesis while upregulating PPARα expression for increased fatty acid oxidation. Furthermore, Uro-A and Uro-B decreased the expression of PERK and IRE1α; which are involved in hepatic ER stress. Taken together, our results showed the potentials of Uro-A and Uro-B in mitigating obesity symptoms and they could thus provide promising roles in the future as functional anti-obesity candidates.
Design choices and thermal simulations of a new test cell facility

The paper presents a new test cell facility, named Box Office and under development at the Ecole Spéciale des Travaux Publics (ESTP Paris) for the analysis and characterization of the thermo-physical properties of building envelope components under real climate conditions. The facility will allow to obtain reliable estimates of thermal performance indicators of transparent and opaque building elements. Particular care has been taken in the design phase in order to minimize or to monitor all sources of uncertainty, such as (i) conductive heat losses through the test cell envelope, (ii) time lag of response to transient outdoor conditions, (iii) levels of airtightness and of resistance to vapour or water penetration. Highly variable solar conditions can seriously affect both the correct functioning of outdoor test facilities and the indoor climate conditions in the cell. For this reason, the thermal behaviour of the Box Office was simulated in Matlab environment, implementing a lumped-parameter model, and results are used for refining the design choices and selecting the most promising operative conditions and control strategies. The output of test cell experiments will be beneficial to various target groups, such as designers and manufacturers (to boost the research and development of new products), research centres (to fully understand and model the physical phenomena occurring in a controlled space facing real outdoor conditions) and potential clients, who ask for economically affordable solutions guaranteeing high levels of Indoor Environmental Quality. The present paper highlights the main features of the test cell under construction at the du within the framework of a collaboration between the end-use Efficiency and ESTP.
Extraction of Three Dimensional Structure From Optical Image Sequences

—Underwater imaging is a big challenge to discover and explore this environment. In this article, we proposed a 3D reconstruction method underwater using multi view 2D images in order to recovery of 3D shape from one or two 2D images. The conventional stereo approach based on perspective camera model cannot be directly applied and instead we used a spherical camera model to depict the relation between 3D point and its corresponding observation in the image. The stereo analysis problem consists of the following steps: image acquisition, camera modeling, feature extraction, image matching and depth determination.Thesensorsystem generates a depth map in which each pixel represents a distance to the sensor. As a result, it can detect not only the presence of objects in the danger zone, but also their relative size and position. The system is implemented to reconstruct 3d scene using two or several three dimensional captures. It is also created to allow users to control the view perspective and obtain a better intuition of how the scene is rebuilt. Experiment results showed that the proposed approach offer a good preservation of the structure in sub-sea environment.
Investigating the Relevance of Sensor Selection: Recognition of ADLs Based on Feet Movement and Posture Information

—In this work, we present an analysis of the relevance of different sensor types for the recognition of activities of daily living based on foot movement and position. By conducting a comprehensive experiment with 12 diverse volunteers that resulted in about 1 million data samples, and employing a machine learning HAR (Human Activity Recognition) classiﬁer developed for a 9-activity classes model, we were able to assess the impact of sensor selection on the activity recognition accuracy. Aiming at a replicable research, we provide full hardware information, system source code and a public domain dataset.
Ascorbic Acid and Bone Mineral Density Simon and Hudes Relation of Ascorbic Acid to Bone Mineral Density and Self-reported Fractures among US Adults

Ascorbic acid is an essential nutrient involved in collagen formation, and its deficiency is associated with abnormal bone development.To examine the relation of ascorbic acid to bone mineral density and the prevalence of self-reported fractures, the authors analyzed data collected from 13,080 adults enrolled in the Third National Health and Nutrition Examination Survey (NHANES III) during 1988–1994. Because they identified three-way interactions among smoking, history of estrogen use, and dietary and serum ascorbic acid in postmenopausal women, they analyzed these relations stratified by smoking and estrogen use. Dietary ascorbic acid intake was independently associated with bone mineral density among premenopausal women ( p = 0.002). Among men, serum ascorbic acid was associated in a nonlinear fashion with bone mineral density ( p < 0.05), and dietary ascorbic acid intake was associated in a nonlinear fashion with self-reported fracture ( p = 0.05). Among postmenopausal women without a history of smoking or estrogen use, serum ascorbic acid was unexpectedly associated with lower bone mineral density ( p = 0.01). However, among postmenopausal women with a history of smoking and estrogen use, a standard deviation increase in serum ascorbic acid was associated with a 49% decrease in fracture prevalence ( p = 0.001). Dietary and serum ascorbic acid measures were associated inconsistently with bone mineral density and self-reported fracture among adult participants in NHANES III. Am J Epidemiol 2001;154:427–33.
International Journal of Advanced Research in Computer Science and Software Engineering

: Software cracking is a serious problem to software protection right. Software cracking is the modification of software in order to remove copyright protection from the software by manipulating the trial/demo version, serial number, hardware key, date checks, etc. Software cracking is a serious threat to commercial software developers worldwide. While deriving exact numbers is hard, it is commonly assumed that the accumulated economic damage from software copyright infringement ranges in the order of several tens of billions of dollars. In this paper, we develop a framework for preventing software cracking network. In this paper, we examine software protection through code obfuscation and encryption technique, known as one - way hashing, which resists reverse engineering attacks. The model is a code transformation technique in which functionality of original code is maintained while obfuscated and one - way hashed code is made difficult to reverse engineer. The key idea is to hide the code. The code was developed using assembly language which makes it difficult to understand thus providing effective technique for preventing cracking through encryption and obfuscation. The result shows that the code is difficult for humans to read and thereby providing effective and watertight mechanism against cracking.
A Comparative Study of the Surgical Outcome of Internationally Adopted versus Swedish Born Children with Cleft Lip and/or Palate

Master thesis in Medicine Background Hospital, internationally adopted patients with a cleft lip and/or palate are treated by a cleft team at the Department of Plastic Surgery. Earlier studies and clinical experience indicate a higher number of surgical complications compared to non-adopted children. To show and surgical and the surgical outcome in internationally adopted patients compared to non-adopted The of the present study was to show the demographics and surgical procedures of adopted cleft patients treated and to investigate if there is a significant difference regarding the quantity of and complications and Studien visar också att adopterade patienter kräver mer än icke-adopterade patienter. Det finns dock inte någon signifikant skillnad gäller icke-adopterad