Miracle-dz/UniFAR-FTUs huggingface dataset:
Coiling Techniques in management of Cerebral Aneurysms Preoperative assessment, Outcome and Complications

Background: according to the International Subarachnoid Trial (ISAT), patients with subarachnoid hemorrhage (SAH) fared better with endovascular coiling than those with surgical clipping (Molyneux et al., 2005). With the emergence of flow diversion as a useful technique in management of cerebral aneurysm, endovascular techniques now have many varieties that enable the interventionalist to achieve best outcome. Objective: This study aimed to compare the outcome and complications between balloon assisted coiling and the use of Flow diverter stent, also studying the theoretical effect of antiplatelet use in flow diverter group and whether there is an added risk for development of bleeding. Patients and Methods: Thirty two patients were included in this study between February/2016 and June/2017. Age range was 25-69 (54± 10.5) for balloon group (Group B =17), 30-68 years old (50.7±10.1) for the Flow diverter group (Group F=15). The females were 10 (58%) in the balloon group and 6 (40%) in the Flow diverter group. No statistically significant difference was found between two groups. Those patient were found to have wide neck aneurysm by either CT cerebral angiography of 4 vessel angiography. Patient undergo preoperative assessment using NIHS stroke scale, modified Rankin scale, Hunt and Hess scale and modified fisher scale. Post-operative assessment included, modified Rankin scale for clinical outcome and Raymond Roy scale for the degree of obliteration of aneurysm. Follow up study was done after 6 month of the procedure including the same sale to detect the clinical improvement as well as recanalization rate. Results: Regarding follow up assessment in clinical outcome, significant improvement occurred in both groups with minimal or no symptoms in 15 out of 17 (88.23%) in the balloon group and 14 out of 15 (93%) in the flow diverter group. Findings show that total obliteration was achieved immediately in most of cases (11 out of 17 in the balloon group, 13 out of 15 in the Flow diverter group). No significant difference between angiographic outcome of immediate and follow up imaging in the case of flow diverter. There is a significant difference between the immediate and follow up score of the balloon group but eventually most of the cases achieve complete obliteration (15 out of 17). Regarding complications, the operation went uneventful for more than 2 thirds of cases in each group. Although thrombotic complication is higher in Flow diverter group (20% for FD Vs 11.8% for B), manifest infarction is paradoxically higher in Balloon group (6.7% for FD Vs 17.6% for B). Hemorrhagic event occurred only once in balloon group (5.9%). For correlation, clinical outcome correlates with radiological outcome (P=0.007 significant level is P<0.001). Conclusion: both techniques are safe and effective in management of wide neck cerebral aneurysm with no significant difference between both techniques. Selection of either method is upon the experience of the interventional neurologist’s experience and preference.
Two parameters identification for polarization curve fitting of PEMFC based on genetic algorithm

Experimental and numerical studies are the main methods to obtain the polarization curves of proton exchange membrane fuel cell (PEMFC) stack for the application of balance of plant (BOP) selection, system matching, and controller design. A novel methodology of polarization curve fitting for PEMFC is proposed based on genetic algorithm, and a rated power of 62 kW fuel cell stack is used for identification experiments. The exchange current density and charge transfer coefficient are selected as optimization variables. The results show that the two optimization variables can effectively replace the four empirical parameters in the calculation of activation overpotential and demonstrate good agreement between the proposed model and experimental data within 3% error. In addition, a group of polarization curves is obtained by considering the relationship between the exchange current density and reactant concentration, activation energy, and temperature, which is of great significance in the engineering application of PEMFC for quick and accurate control. Furthermore, a dynamic model is also used to investigate the transient response of PEMFC, and the simulation results show a transition region of voltage drop at step current densities, coinciding with the experimental data and indicating the reliability of the method for polarization curve fitting.
Isolated Pattern of Microorganism among Pediatric Patients with Ventilator-associated Pneumonia (VAP) in a Tertiary Care Hospital Karachi

Background: The Ventilator associated pneumonia (VAP) is a common condition with inflammation of lungs. The patients on mechanical ventilation or artificial breathings for 48 to 72 hours tend to developed this condition. , which is a type of Nosocomial Pneumonia. Objective: To assess the causative agent and treatment pattern among the patients suffering from ventilator associated pneumonia. Methodology: A cross sectional study was conducted for the period of 8 months at a tertiary health care setup of the Karachi Pakistan among the patient’s with VAP. Total of 72 patients with confirmed diagnosis of VAP were included in the study. Data was collected from the children intensive care units on a structed questionnaire. The required variables were obtained from the patients files/Records after the ethical approval was obtained before the collection of data Results were evaluated using the SPSS version 20.0. Results: The study found out that the VAP is most type of hospital acquired pneumonia form the health care system. , showed 59.8% (n=61) males and 34.3% (n=35) females’ patients with VAP diagnosis. The age group revealed majority of the patients 46.1% (n=47) were 0–1-year-old, 11.8% (n=12) patients were above 2- 3 years old. 18.6% patients (n=19) were >3 years-4years old. The study also assesses ventilators support >48 hours have around 20-30% (Mean 6.9 days CI: 1.16-3.65) chance to develop the VAP. The subsequent effects of VAP shows the two-fold rates of mortality hence requiring the more length of stay at hospital and extra charges. Conclusion: The VAP occurs among the considerable numbers of patients on the ventilator supports, the findings suggests that an appropriate management, prevention strategies and effective treatment is needed to reduces the mortality and complications of VAP.
Evidence of Aggregation Dependence of 5-degree Scale Tropical Convective Evolution Using a Gross Moist Stability Framework

Spatial aggregation of deep convection and its possible role in larger-scale atmospheric behavior have received growing attention. Here we seek aggregation-correlated statistical properties of convective events in 50×50 boxes over the tropical Indian ocean. Events are identified by box-averaged rainfall exceeding 5 mm day−1 at the center of a 4-day time window, and aggregation is estimated by an index (SCAI) based on contiguous cold cloud areas and their geometrical distances in infrared imagery. A physical framework using gross moist stability (GMS) helps to interpret relationships between aggregation, box-scale ascent profiles, moist static energy budgets, and time evolution both within composite events and on longer timescales. For a given precipitation rate, more-aggregated events (with fewer and larger cloud objects on average) exhibit a drier area mean, greater horizontal gradient of moisture, more bottom-heavy ascent profile, and a greater prevalence of low-altitude cloud tops, especially for lower rain rates. In the GMS budget, this bottom-heavy ascent implies net energy import into the atmospheric column during the 4-day event composite. Consistently, net energy variations filtered to reveal longer timescales do indeed exhibit more-aggregated rain events in their growth phase than in their flat and decaying phases. More-aggregated scenes also have more drying by analysis than less-aggregated scenes in MERRA-2’s assimilation budgets. This suggests that parameterized convection (lacking any organization effect) is raining out less water than nature’s real, aggregated convection in such scenes.
Piperine Attenuates Lithocholic Acid-Stimulated Interleukin-8 by Suppressing Src/EGFR and Reactive Oxygen Species in Human Colorectal Cancer Cells

Piperine, a natural alkaloidal pungent product present in pepper plants, possesses the properties of anti-inflammatory and anti-metastasis. Lithocholic acid is a monohydroxy-5beta-cholanic acid with an alpha-hydroxy substituent at position 3; it is a secondary bile acid that plays a pivotal role in fat absorption, and has been discovered to mediate colorectal cancer (CRC) cell invasion and migration. However, the effect of piperine on angiogenesis has been poorly investigated. In the current study, we examined the role of piperine on LCA-stimulated angiogenesis by measuring interleukin-8 (IL-8) expression; moreover, we revealed the potential molecular mechanisms in CRC cells. Here, we showed that piperine inhibited LCA-stimulated endothelial EA.hy926 cell angiogenesis in a conditioned medium obtained from colorectal HCT-116 cells. Experiments with an IL-8 neutralizer showed that IL-8 present in the conditioned medium was the major angiogenic factor. Piperine inhibited LCA-stimulated ERK1/2 and AKT via the Src/EGFR-driven ROS signaling pathway in the colorectal cell line (HCT-116). Through mutagenesis and inhibitory studies, we revealed that ERK1/2 acted as an upstream signaling molecule in AP-1 activation, and AKT acted as an upstream signaling molecule in NF-κB activation, which in turn attenuated IL-8 expression. Taken together, we demonstrated that piperine blocked LCA-stimulated IL-8 expression by suppressing Src and EGFR in human CRC HCT-116 cells, thus remarkably attenuating endothelial EA.hy926 cell tube formation.
Relationship of Diabetes Mellitus (DM) and Ischemic Heart Disease: Review Article

Background: Diabetes mellitus (DM) is one the strongest risk factors for cardiovascular disease and, in particular, for ischemic heart disease (IHD). The pathophysiology of myocardial ischemia in diabetic patients is complex and not fully understood. Some diabetic patients have mainly coronary stenosis obstructing blood flow to the myocardium and others present with coronary microvascular disease with an absence of plaques in the epicardial vessels. Objective: This review article aimed to study diabetes mellitus in order to reduce the high morbidity and mortality due to cardiovascular disease in diabetic patients. Methods: These databases were searched for articles published in English in 3 data bases [PubMed – Google scholarscience direct] and Boolean operators (AND, OR, NOT) had been used such as diabetes mellitus and ischemic heart disease or coronary artery disease and in peer-reviewed articles between July 1998 and April 2021. A 23-year date range was selected without language limitations, and filtered in selected data basis for the last 23 years. Documents in a language apart from English have been excluded as sources for interpretation. Papers apart from main scientific studies had been excluded (documents unavailable as total written text, conversation, conference abstract papers and dissertations). Conclusion: Diabetes mellitus, a simultaneously endocrine and metabolic disease, is an especially aggressive process leading to vascular lesions. In order to reduce the high morbidity and mortality due to cardiovascular disease in diabetic patients the goals of prevention must be maximal on non-diabetic persons who already have ischemic heart disease.
ICT for Disaster Management

Information and Communications Technology (ICT) can be used to minimize this impact in many ways. ICT is used in almost all phases of the disaster management process. In the disaster mitigation and preparedness process, ICT is widely used to create early warning systems. An early warning system may use more than one ICT media in parallel and these can be either traditional (radio, television, telephone) or modern (SMS, cell broadcasting, Internet). As demonstrated by AlertNet, on-line media play an important role.
Impact of COVID‐19 lockdown on the elemental profile of PM10 present in the ambient aerosol of an educational institute in Kolkata, India

Abstract Reduction in air pollution level was prime observation during COVID‐19 lockdown globally. Here, the study was conducted to assess the impact of lockdown on the elemental profile of PM10 in ambient aerosol to quantify the elemental variation. To quantify the variation, phase‐wise sampling of air pollutants was carried out using the gravimetric method for PM10, while NO2 and SO2 were estimated through the chemiluminescence and fluorescent spectrometric method respectively. The elemental constituents of PM10 were carried out using an Inductively Coupled Plasma Optical Emission Spectrometer and their source apportionment was carried out using the Positive Matrix Factorization model. The results showed that PM10, NO2 and SO2 reduced by 86.97%, 83.38%, and 88.60% respectively during the lockdown sampling phase. The highest mean elemental concentration reduction was found in Mn (97.47%) during the lockdown. The inter‐correlation among the pollutants exhibited a significant association indicating that they originate from the same source. The metals like Mn and Cu were found at a higher concentration during the lockdown phase corresponding to vehicular emissions. The comparative analysis of the elemental profile of PM10 concluded that the lockdown effectuated in reduction of the majority of elements present in an aerosol enveloping metropolitan like Kolkata.
Asynchronous variations of East Asian summer monsoon, vegetation and soil formation at Yulin (North China) in the Holocene

In the East Asian monsoon region, Chinese speleothem δ18O records exhibit a maximum monsoon strength during the early Holocene. However, other proxy data from lakes or loess, interpreted as monsoon rainfall, show a mid‐Holocene monsoon optimum. This discrepancy may come from specific climate interpretation of different proxies. Here we report multiproxy records from a single loess–palaeosol sequence at Yulin in the monsoon marginal northern China, based on an independent and high‐precision chronology. Our long‐chain n‐alkane δD values, together with related biomarker proxies including the average chain length and concentration of long‐chain n‐alkanes, reveal a weakening trend in monsoon strength and less woody vegetation since ~6 ka. However, other soil formation‐related proxies, such as magnetic susceptibility, grain‐size distribution and total organic carbon, show a decreasing trend since 4–3 ka. We find that monsoon and vegetation are controlled by insolation variation, while soil formation is more related to temperature and humidity changes. Our multiple proxy comparison reveals different controlling mechanisms leading to different interpretations in monsoon, vegetation and soil formation reconstructions. This finding suggests that previous debates on Holocene monsoon changes in East Asia probably stem from the specific proxy interpretation.
POST-DISCHARGE FOLLOW UP OF GROWTH IN LOW BIRTH WEIGHT INFANTS

Background: Low birth weight (LBW) is one of the leading causes of perinatal and infant morbidity and mortality, as well as of impaired growth and neurocognitive development. Aim and objectives: Evaluation of growth parameters (weight, length and head circumference) at birth, 2, 4, and 6 months of LBW infants after discharging from NICU. Patients and methods: A prospective follow up study was conducted on 100 infants weighing < 2,500 g and admitted to NICU of Abulmatamir Central Hospital in Beheira Governorate in the period from May/2018 to March/2020. All infants were selected by simple random method. Infant's weigh (g), length (cm), and head circumference (cm) were measured at birth, 2, 4, and 6 months, plotted against WHO growth charts for their catch-up growth follow up. Measurements were calculated using mean and standard deviation. Data were analyzed using SPSS version 15 statistical software. Result: There was highly statistical significant difference regarding weight, length and head circumference at 6th month in the studied infants. No statistical significant difference between males and females regarding weight and length except for weight at 6 months when males appeared to have a better weight. There was statistical significant difference in regard of head circumference between males and females. There was highly statistical significant difference as regard weight, length and head circumference between breastfed and formula fed infants. Conclusion: Low birth weight infants showed catch-up growth during the first 6th months, but their weight, length and HC remained less than reference population. Breastfed infants show better catch-up growth than formula fed infants. Both males and females had the same catch up growth for weight and length except for weight at 6 months when females appeared lighter. Girls appeared to have a smaller head circumference than boys.
Aggregated CDMA Crossbar with Hybrid ARQ for NoCs

Network-on-Chips (NoCs) are the dominant interconnection technique in modern System-on-Chips (SoCs). NoC routers constitute the physical layer of on-chip interconnects while the medium access technique utilized in NoC routers profoundly impacts the performance and footprint of the router. Code Division Multiple Access (CDMA) is one of the prominent access techniques employed in the physical layer crossbar of NoC routers. Adopted from the wireless communications realm, the CDMA-based crossbar relies on spreading the transmitted data bit on the physical channel using orthogonal codes, summing the data spread from various transmitters, then decoding the received sum using correlation decoders to extract the sent binary bit. However, due to multiple access interference and random channel effects notorious in wireless communications and following the same exact approach in on-chip CDMA interconnects, existing CDMA crossbars are bit-wise architectures where binary data bits are spread and serially communicated on an exclusive digital channel while replicating this configuration to communicate multi-bit packets which increases the crossbar area overhead. We advance an elegant modification to improve the area and power consumption of the classical CDMA crossbars. Aggregated CDMA (ACDMA) relies on high wiring density in modern SoCs in addition to its static nature and relative noise immunity to improve the classical CDMA crossbar architecture by aggregating the transmission of multiple data bits on the same channel which reduces the overhead of ordinary CDMA-based NoCs. In this work, the ACDMA mathematical foundations, crossbar hardware architecture, and full NoC realizations are presented. The implementation results on the 65 nm standard-cell ASIC technology show a significant improvement in the resource utilization and power consumption of the ACDMA crossbar and ACDMA-based NoCs compared to the ordinary CDMA and CONNECT NoC counterparts. Moreover, the ACDMA interconnect reliability in AWGN channels is studied and improved using a hybrid ARQ approach tailored to the ACDMA crossbar.
EFFECT OF MINERAL AND BIOFERTILIZERS ON GROWTH, YIELD, TUBER ROOT QUALITY AND STORABILITY OF SWEET POTATO PLANTS GROWN IN SANDY SOIL

This work was carried out during the two successive summer seasons of 2003 and 2004 at El-Khattara Experimental Farm, Fac. Agric. , Zagazig University, to evaluate the effect of single and combined applications of mineral and biofertilizers on growth, yield and its components, tuber root quality and storability of sweet potato cv. Mabroka under sandy soil conditions. Nitrobein (Nr) was used as a nitrogen fixing bacteria in addition to phosphorein (Pr) as a phosphate dissolving bacteria. Fertilization of sweet potato plants with NP mineral fertilizers at 100% of the recommend rates (80 N + 60 P2O5 ) kg/fed , or N + P fertilizers combined with the biofertilizers phosphorein (Pr) or nitrobein (Nr) at different rates and combinations of 80 N + 30 P2O5 + 0.6 Pr , 80 N + 15 P2O5 + 1.2 Pr, 40 N + 60 P2O5 + 1 Nr , 20 N + 60 P2O5 + 2 Nr , 40 N + 30 P2O5 + 1 Nr + 0.6 Pr and 20 N + 15 P2O5 + 2 Nr + 1.2 Pr ( kg/ fed) , significantly increased plant growth characters (vine length, number of both branches and leaves / plant and dry weight of different plant parts, number of tuber roots/ plant and total yield , comparing with using biofertilizers alone . In general, fertilization of sweet potato with N+P at 80 kg N +60 kg P2O/ fed or the combinations of N+P and Nr +Pr at different rates gave the highest values of average tuber root weight, yield /plant and yield of oversized, marketable and total yield, whereas, Nr and Pr at different rates without mineral fertilizers gave the lowest values of yield and its components. However, inoculation of sweet potato plants with biofertilizers without mineral fertilizers, gave tuber roots with good quality and storability concerning TSS, total carbohydrates, total sugars, weight loss and sprouting of tuber roots with non significant differences between them. Therefore, treating sweet potato plants with 1 kg (Nr) + 0.6kg (Pr) + 40kg (N) + 30kg (P2O5), can be recommended to improve productivity, tuber root quality, storability as well as reducing the need for minerals and in turn reduced the cost of production and also decreased the environmental pollution.
Some hormonal changes related to some trace elements deficiency in ration of male lambs

T race element deficiency in male lambs is a serious problem. It refers to either insufficient nutrients or mineral elements imbalance. This work aimed to investigate the hormonal and some biochemical changes related to some trace element deficiency and the effect of mineral mixture supplementation on these changes. To achieve this aim we induced trace element deficiency in a tested male lambs group (N=10) belonged to our sheep herd and received a mineral mixture as a feed supplement for 10 days. The analysis of tested diet revealed protein 12.32%, calcium 1.21%, phosphorus 0.27%, and zinc 25.96 mg/kg DM. While the control healthy group (N=10) received a traditional diet. The results of serum hormones and biochemical analysis of tested group revealed a significant (P˂0.05) decrease in TSH, T3, T3/T4, testosterone, free testosterone, SHBG, GH, albumin and zinc, with a significant (P˂0.05) increase in T4, total protein and globulin compared to control healthy group. On the other hand, the results obtained after mineral mixture supplementation revealed a significant (P˂0.05) increase of TSH, T3, T3/T4, testosterone, free testosterone, SHBG, GH, albumin and zinc. Also, a significant (P˂0.05) decrease in T4, total protein, and globulin was observed compared with this group before mineral mixture supplementation, with observation of the changes were gradually toward recovery. Moreover, insignificant changes were recorded in calcium, phosphorus and iodine. In conclusion to trace element deficiency have an effect on vital hormones with extension to metabolic process, general health condition and proper growth of male lambs.
Research on sEMG Based gesture recognition by dual-view deep learning

In the field of human-machine interaction, gesture recognition using sparse multichannel surface electromyography (sEMG) remains a challenge. Based on the Hilbert filling curve, a dual-view multi-scale convolutional neural network (DVMSCNN) is designed to enhance gesture recognition performance in this paper. The network consists of two parts. In the first part, sEMG is filled using Hilbert filling curve, and the obtained images in the time and electrode domain are used as inputs to the block. In the second part, the depth features learned by block are fused and classified by a "layer fusion" based view aggregation network. The evaluation of the architecture in the four databases of Ninapro-DB1, DB2, DB3 and DB4 shows that DVMSCNN is more than 7% more accurate than other state-of-the-art methods. When validated using a home-grown dataset, DVMSCNN was able to achieve a recognition rate of 0.8848.