Miracle-dz/UniFAR-FTUs huggingface dataset:
Substance use among adults living on the streets and association with mindfulness

Objective: to analyze the relationship between the level of mindfulness and the problematic use of alcohol and drugs in homeless people. Method: a cross-sectional study was conducted with 40 users of a homeless adult service. They were interviewed using the MAAS scales (Mindful Attention Awareness Scale), CAGE (Cut down, Annoyde by criticims, Guilty and Eye-opener) and AUDIT (Alcohol Use Disorders Identification Test), as well as a sociodemographic questionnaire. Results: high prevalence of substance abuse in this sample, and a negative correlation between the problematic use of alcohol and drugs and the level of mindfulness, which may indicate that low levels of mindfulness may be a risk factor for the addicted population. Conclusion: the use of meditation in interventions with this population is suggested. de calle. Método: estudio de corte transversal con 40 usuarios de un servicio de convivencia de adultos en situación de calle o de refugio. Contestaron, durante una entrevista, las escalas MAAS ( Mindful Attention Awareness Scale ), CAGE ( Cut down, Annoyde by criticims, Guilty and Eye-opener ) y AUDIT ( Alcohol Use Disorders Identification Test ), así como un cuestionario sociodemográfico. Resultados: alta prevalencia de abuso de sustancias en esta muestra y mostraron una correlación negativa entre el uso problemático de alcohol y drogas y el nivel de atención plena, lo que indica que bajos niveles de mindfulness pueden ser un factor de riesgo para la población adicta. Conclusión: se sugiere el uso de meditación en intervenciones con esa población.
The Effect of M-Banking Service Quality and Customer Perceived Value to Satisfaction and Loyalty of Bank XYZ Customers

Many banks in Indonesia have been conducting surveys to customers related to services at branch offices (Branch Service Quality) and Customer Engagement with results that continue to growevery year. With the advancement of digital technology, counter services have begun to shift to digital channels, especially mobile banking. Existing research related to the use of mobile banking uses e-servquality more often, which is generally used in research to see the excellence of services in internet banking, online shops, and digital marketplaces. Therefore, we consider it is necessary to carry on a research about the effect of mobile banking service quality on customer satisfaction and loyalty, the effect of customer perceived value on customer satisfaction and loyalty, and the effect of customer satisfaction with customer loyalty. The research was conducted by setting a sample of Bank XYZ customers who use Bank XYZ mobile banking, the total is 505 respondents. Structural equation modeling was used to carry outconfirmatory factor analysis and path analysis. From the results, it can be seen that mobile banking service quality and customer perceived value have a significant effect on customer satisfaction, but no significant effect on customer loyalty. Meanwhile, customer satisfaction has a significant effect on customer loyalty.
RRTM_A_278140 181..196

1Department of Medical Parasitology, Post Graduate Institute of Medical Education and Research, Chandigarh, India; 2Department of Medical Microbiology, Post Graduate Institute of Medical Education and Research, Chandigarh, India Abstract: Soil-transmitted helminth (STH) infections (hookworms, Trichuris, Ascaris) and Strongyloides spp. are associated with a substantial global burden and high morbidity. Sensitive and specific methods for diagnosis of these infections are essential for mapping the burden in communities, accurate assessment of infection levels, to guide interventions and monitoring the success of STH control programs. Despite considerable progress to control STH over several decades, we are still far from identifying a fully adequate diagnostic test. Conventional microscopy-based methods such as direct Kato–Katz smear or mounts after stool centrifugation/ flotation-based concentration techniques have been the mainstay of diagnosis, especially in resource-poor countries where these infections abound. However, recently, these are being adapted to closed, easy to perform, digital formats, thereby improving the sensitivity as well as applicability in a remote, resource-limited setting. The use of image analysis systems to identify and quantify helminth eggs, with potential adaptation to smartphones, is also promising. Antibody detection tests have a limited role mostly in the case of Strongyloides hyperinfection. Coproantigen detection tests have been developed and used in veterinary practice for detection of STH, but these have not been evaluated for use in humans. More sensitive molecular diagnostics, including assays developed with new bioinformatic tools and techniques such as polymerase chain reaction (PCR), quantitative PCR (qPCR) and loop-mediated amplification assay, can help in the clear and precise assessment of STH burden during elimination phase and are of immense value for diagnosis in areas with low endemicity and in travelers to endemic regions. Moreover, the molecular techniques will help detect new species that may emerge. Sample preservation and efficient DNA extraction are critical and significantly affect the efficiency of molecular diagnostic tests. In addition to the diagnosis of clinical or asymptomatic infection in humans, detection of STH eggs in environmental samples is imperative to boost STH control efforts. Overall the diagnostic performance, cost-effectiveness, ease of performance, rapidity and in-field applicability of any test should be considered when choosing from the various diagnostic assays in areas with different endemicity, in addition to striving towards the development of novel technologies and optimization of existing methods.
CMAR_A_249790 2743..2752

Department of Pathology, The Second Hospital of Jilin University, Changchun, Jilin, People’s Republic of China Background: Spread through air spaces (STAS) is a spreading phenomenon of lung cancers, which is defined as tumor cells within air spaces in the lung parenchyma beyond the edge of the main tumor. To date, several articles have reviewed the studies concerning the significance of STAS; however, most articles focused on the prognosis without summarizing the significance of STAS on other aspects. In this review, we comprehensively summarized the current literature related to STAS, so as to explore the clinical significance of STAS from multiple perspectives. Main Body: This section provided a comprehensive overview of the significance of STAS from multiple perspectives and summarized current controversies and challenges in the diagnosis and clinical application. Conclusion: STAS is a conspicuous spreading phenomenon of lung cancers indicating worse prognosis; nevertheless, the treatment strategy for patients with STAS remains to be discussed. Further studies are needed to elaborate whether a STAS-positive patient who underwent limited resection needs a second operation or postoperative adjuvant treatment. Meanwhile, the internal mechanism of STAS formation is largely undiscovered. Whether the capability of detachment-migration-reattachment in STAS tumor cells is achieved at the time of primary tumorigenesis or in the progress of tumor development needs to be studied, and the related signal pathways or genetic alterations need to be explored. With this information, it may be possible to improve the prognosis of patients with STAS-positive lung cancers.
Abstract. Dysregulation in the cutaneous wound‐healing process is a consequence of alterations in the efficiency and activity of the various components involved in the healing

Dysregulation in the cutaneous wound‐healing process is a consequence of alterations in the efficiency and activity of the various components involved in the healing process. This dysregulation may result in various clinical appearances of a lesion, such as skin ulcers, keloids, hypertro‐ phic and atrophic scars. The collagen type V alpha 2 (COL5A2) gene provides a template for a component of type V collagen, found primarily within the skin basement membrane. Transforming growth factor (TGF)‐β is involved in inflam‐ mation, angiogenesis, proliferation of fibroblasts, collagen synthesis and extracellular matrix remodeling. Hypertrophic scar fibroblasts possess a disrupted expression pattern of the TGF‐β signaling compared to normal healing, while an increased TGF‐β signaling reduces the epidermal proli‐ feration rate, triggering atrophic scarring. In the present study, 71 female patients who had undergone planned Caesarean section, without postoperative complications, were examined. These patients were clinically and molecularly evaluated after developing scars in order to determine the role of TGF‐β1 (rs201700967 and rs200230083) and COL5A2 (rs369072636) in pathological scarring. Clinical scar evaluation was carried out using SCAR and POSAS scales and genotyping was performed by RT‐PCR. No statistical differences were found between the subgroups regarding the genotype and the patho‐ logical scarring, since all the patients included were wild‐type allele carriers. Further investigations and a more representative study group may highlight the involvement of COL5A2 and TGF‐β1 single nucleotide variants in pathological scarring.
Informal Sector in India: Migration and Poverty Implications

For assessing the role of urbanization in reducing poverty this paper based on secondary datatries to examine the nature of relationship among urbanisation, migration and informal sector employment. Findings suggest that the informal sector also tends to attract migrants as the probability to get work opportunities in this sector could be high. Further, rural and urban poverty are inter-connected as rural to urban migration and informal sector employment and other state-specific characteristics are associated, though migration and urbanisation with its spill-over effects reduce both rural and urban poverty. Also,based onthe survey data for unincorporated enterprises, the paper examinesif the unorganized or informal manufacturing, trade and services have the potentiality to grow and contribute to the realization of the inclusive growth objective. The inter-sectoral linkages do not necessarily mean that productivity and wages improve in the informal sector if the units manage to receive business contract from the formal sector enterprises. In fact, a large body of the informal sector is seen to be unconnected to the formal sector and this independent segment is on the rise over time. Finally the paper argues for the introduction of an informal sector policy which may help reduce the welfare losses to labour employed at the lower rungs
CROWDBC: A Blockchain-Base Decentralized Framework for Crowdsourcing

Due to lack of server reliability and user data privacy encryption of data is required before the cloud is outsourced. We have found a compromised method within the blockchain in order to perform a keyword search which is secured on data that is encrypted against malicious service providers and users in cloud. SSE: Privately offers the cloud storage used in symmetric search encryption (SSE) systems, which cannot be regarded as a true cloud. The cloud service is also known to be credible. Let us start by emphasizing the importance of data storage within a public chain. The client is allowed by system to upload them in form which is encrypted, data content is distributed to the nodes of cloud and make sure that the data is available through encryption techniques. Presentation of a blockchain based system for providing the keyword search service with secure storage of distributed data. TKSE performs verifiability on server side so that true cloud servers are protected from being posed by owners of malicious data in the data storage process. Furthermore, technology of blockchain and hash functions are used to allow payment which is fair without third parties involvement for research fees, although if cloud or user is harmful. Our review of security and evaluation of performance show that TKSE is efficient and safe and be suited for cloud computing.
Novel Mutation of the TGF-β 3 Protein (Loeys-Dietz Type 5) Associated With Aortic and Carotid Dissections

Objectives Loeys-Dietz syndrome (LDS) is a rare genetic cause of stroke associated with connective tissue disorders but is not well known among stroke physicians.1 The main objectives of this case report are to increase awareness of this condition and to improve stroke prevention at follow-up visits. Methods A patient with aortic and carotid artery dissection who had undergone 2 major aortic surgeries with mechanical composite graft and treated with full-dose anticoagulation was reevaluated by neurologists due to retinal hypoperfusion symptoms. After musculoskeletal examination, cervical ultrasonography, and computerized tomography angiography, he was referred for whole-genome sequencing. Results We found joint hypermobility, skin hyperelasticity, bifid uvula, and combined cervical artery dissections that caused intermittently decreased blood flow in the left ophthalmic artery and an acute asymptomatic embolic stroke. A novel pathogenic variant of LDS type 5 consisting of a heterogeneous nonsense variant c.1044C>A, p.(Cys384*) was found in the TGF-β 3 (TGFB3) gene. Consequently, anticoagulation was intensified, and at 1-year follow-up, the patient's symptoms improved. Discussion This novel genetic variant coupled to the patient's phenotype contributes to the knowledge of genetic causes of stroke. Patients with multiple arterial dissections and musculoskeletal features should be offered genetic testing and be carefully evaluated to avoid further cerebrovascular ischemic lesions.
A Conceptual Framework to Aid Attribute Selection in Machine Learning Student Performance Prediction Models

One of the important key applications of learning analytics is offering an opportunity to the institutions to track the student’s academic activities and provide them with real-time adaptive consultations if the student academic performance diverts towards the inadequate outcome. Still, numerous barriers exist while developing and implementing such kind of learning analytics applications. Machine learning algorithms emerge as useful tools to endorse learning analytics by building models capable of forecasting the final outcome of students based on their available attributes. The machine learning algorithm’s performance demotes with using the entire attributes and thus a vigilant selection of predicting attributes boosts the performance of the produced model. Though, several constructive techniques facilitate to identify the subset of productive attributes, however, the challenging task is to evaluate if the prediction attributes are meaningful, explicit, and controllable by the students. This paper reviews the existing literature to come up with the student’s attributes used in developing prediction models. We propose a conceptual framework which demonstrates the classification of attributes as either latent or dynamic. The latent attributes may appear significant but the student is not able to control these attribute, on the other hand, the student has command to restrain the dynamic attributes. Each of the major class is further categorized to present an opportunity to the researchers to pick constructive attributes for model development.
Bitcoin Plus: Peer-to-Peer Crypto-Currency with Proof-of-Stake

A peer-to-peer crypto-currency design derived from Satoshi Nakamoto’s Bitcoin. Proof-of-stake replaces proof-of-work to provide most of the network security. Under this hybrid design proof-of-work mainly provides initial minting and is largely non-essential in the long run. Security level of the network is not dependent on energy consumption in the long term thus providing an energy-efficient and more cost-competitive peer-to-peer crypto-currency. Proof-of-stake is based on coin age and generated by each node via a hashing scheme bearing similarity to Bitcoin’s but over limited search space. Block chain history and transaction settlement are further protected by a centrally broadcasted checkpoint mechanism.
Oral Microbiome: Metagenomics in Oral Health

It is now well known by the general population that our gastrointestinal tract is inhabited, that the human insides are colonized by billions of bacteria, and that we are not alone in our body. People are more and more aware of the presence of various microbiota in or on our body. The most well-known is the gut microbiota, but more recently oral, vaginal and skin microbiota have earned some attention. Some time ago, it was believed that the bacteria were deleterious, that they had to be removed from our lives. Soaps were very strong and bactericidal, toothpastes and mouth rinses aimed to remove 99.9% of oral bacteria. Nowadays, new care products have been developed to respect human skin, mucosa and their endogenous microflora. Some of them even try to influence these commensal ecosystems in a positive manner. This important change in the general population’s way of thinking stems from a better understanding and knowledge of human microbiomes, thanks to high through-put technology such as metagenomics and sequencing. This review will focus on the oral microflora. Firstly, we will describe what metagenomics is in terms of evolution of technology, and then its use in the studies of the influence of living conditions. Secondly, the link between the oral microbiome and systemic health will be discussed. Finally, we will see how the oral microbiota can be modulated by health status or by external factors.
CMAR_A_250772 3343..3352

Ning Lin* Wentao Li* Xiefeng Wang* Shiqiang Hou 1 Dong Yu Xingyuan Zhao Chunjing Jin Guoquan Yao Wei Yan Yongping You 1Department of Neurosurgery, Chuzhou Clinical College of Anhui Medical University, The First People’s Hospital Chuzhou, Chuzhou, People’s Republic of China; 2Department of Neurosurgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, People’s Republic of China; 3Laboratory Medicine Center, Affiliated Hospital of Nantong University, Nantong, People’s Republic of China
Phytochemical analysis and protective effect of ethanolic extract of Mimosa pudica Linn. on methylglyoxal-induced glucotoxicity

Pham Thi Lan2, Nguyen Thi Ngoc Huyen1, Sun Yeou Kim4, Pham Thi Nguyet Hang3, Bui Thanh Tung1* 1Deparment of Pharmacology and Clinical Pharmacy, University of Medicine and Pharmacy, Vietnam National University, Hanoi, Vietnam. 2Faculty of Pharmacy, Hanoi University of Business and Technology, Hanoi, Vietnam. 3Department of Pharmacology, National Institute of Medicinal Materials, Hanoi, Vietnam. 4Laboratory of Pharmacognosy, College of Pharmacy, Gachon University, Incheon, Republic of Korea.
Effets d'un exercice de type anaérobie sur le statut antioxydant enzymatique au cours de la récupération chez les judokas Effects of anaerobic exercise on the status of enzymatic antioxidants among Judo athletes during recovery level

Aim. – To evaluate the effect of the anaerobic exercise on the enzymatic antioxidant statute in judokas’ regional level, because the effects of anaerobic exercise on the free radicals and antioxidants are relatively rare and have some divergences. Materials and methods. – We made this study on ten male judokas (age = 18.1 ± 1.6 years; weight = 77.2 ± 11.6 kg; height = 176.4 ± 4.6 cm), which carried out 30 seconds anaerobic capacity test (Wingate test). Blood samples were taken, by an intravenous catheter, at rest (R), immediately after the Wingate test (P0) then five minutes later (P5), 10 minutes later (P10) then 20 minutes later (P20). The measured parameters are: the superoxide dismutase (SOD), the glutathion peroxidase (GPx) and the total antioxidant statute (SAT). Results. – The concentration of the SOD increases significantly (p < 0.05) at (P0); and regains the baseline values at (P20). The concentration of GPx increases significantly (p < 0.05) in (P0); in (P10) GPx reaches the baseline values. No significant effect of the anaerobic exercise was observed on the concentration of the SAT. Positive correlation was observed between the SOD and GPx to p < 0.05. Conclusion. – The anaerobic exercise modifies the activity of the antioxidant enzymes with different kinetics. © 2008 Elsevier Masson SAS. Tous droits reserves.
Self-consistent cross-field transport model for core and edge plasma transport

A two-equation model to self-consistently determine cross-field fluxes in the edge and scrape-off layer (SOL) region of diverted plasma is used to complete 2D mean-field edge transport description of plasma wall interaction. Inspired by the Reynolds average Navier–Stokes simulations for neutral fluids, this model is based on the local evolution of the turbulent kinetic energy κ and its dissipation rate ɛ. These two equations are algebraically derived for RANS modeling and are very slightly modified and adapted to describe self-consistent plasma turbulent transport. The general features of the model are discussed and bridged to the well-known predator–prey and quasilinear models commonly used to investigate plasma transport. Specific closures are proposed based on the interchange turbulence. Results of the 1D model are confronted to experimental evidence by analyzing the computed SOL width and comparing the results to the existing scaling law for L-mode plasmas. Introducing a dependence on the shear of large scale flows, typically the zonal flows, 1D simulations can exhibit an H-mode like transition when increasing the input power, generating an increased stored energy thanks to an interface barrier located at the separatrix. Further 2D plasma–wall interaction simulations for WEST are analyzed that show a good match with the experimental profiles, as well as a ballooned transport driving turbulent transport in the divertor SOL and nearly no transport in the private flux region. The SOL width of WEST is also recovered. These results show the remarkable capability of the κ–ɛ model to capture key aspects of the physics of turbulent transport throughout the plasma knowing that a unique scalar free parameter is available to tune cross field transport in the whole 2D cross section of the plasma.
Sexual Exploitation of Women with Schizophrenia

Sexual coercion and exploitation of vulnerable populations children, the elderly, the physically disabled, the mentally disabled, the poor and the gullible are major societal problems throughout the world. Both sexes are at risk, but the likelihood of victimization is highest among women. The multiple disabilities of women with severe mental illness appear to render them especially vulnerable to such exploitation. Disabled persons are known to experience significantly more violence (physical, sexual and intimate partner violence and stalking/ harassment) than those without disability, as shown in a recent Australian study of more than 17,000 adults (Krnjacki et al., 2016). This study noted gender differences: women with disabilities were more likely to experience sexual and partner violence whereas men with disabilities were more likely to experience physical violence. A 2012 systematic review of this topic had already reached the same conclusion (Hughes et al., 2012). In the United States, 36% of women with disabilities report intimate partner violence (Hahn et al., 2014; Mitra and Moradian, 2014). Women with psychological disabilities are targeted more than others by both intimate partners and non-domestic perpetrators (Plummer and Findlay, 2012). Non-domestic violence is reportedly three times as prevalent in the United Kingdom (UK) in those with mental illness compared to those without (Khalifeh et al., 2013). In the Netherlands, both men and women with severe mental illness are reportedly targets for criminal violence (Kamperman et al., 2014) and this has been shown elsewhere as well (Chapple et al., 2004; Coverdale and Turbott, 2000; Maniglio, 2009; Mauritz et al., 2013; Teasdale, 2009). This paper reviews sexual exploitation of women with schizophrenia-related disorders in order to determine prevalence, risk factors, sequelae, and preventive measures. American Research Journal of Addiction and Rehabilitation Volume 1, Issue 1, pp: 22-29