Miracle-dz/UniFAR-FTUs huggingface dataset:
Capability presence in the newly

We investigate the enablers of early internationalization of the firm. We posit that for firms to internationalize early in their lifecycles, sets of capabilities must be present at the firm’s formative stage and that these capabilities build upon routines that the founders bring into the new firm. These capabilities are aligned to establish a platform for internationalization unencumbered by the administrative heritage often observed in well-established firms. We model this phenomenon, testing it in a cross-national setting of early internationalizing firms in Australia and the United States. To do so, we draw upon a dynamic capabilities framing, conceptualizing and measuring the dynamic capabilities that founders apply in their early internationalization activities.
Reactive transport codes for subsurface simulation

A general description of the mathematical and numerical formulations used in modern numerical reactive transport codes relevant for subsurface environmental simulations is presented. The formulations are followed by short descriptions of commonly used and available subsurface simulators that consider continuum representations of flow, transport, and reactions in porous media. These formulations are applicable to most of the subsurface environmental benchmark problems included in this special issue. The list of codes described briefly here includes PHREEQC, HPx, PHT3D, OpenGeoSys (OGS), HYTEC, ORCHESTRA, TOUGHREACT, eSTOMP, HYDROGEOCHEM, CrunchFlow, MIN3P, and PFLOTRAN. The descriptions include a high-level list of capabilities for each of the codes, along with a selective list of applications that highlight their capabilities and historical development.
Mechanisms of Late and Very Late Bioresorbable

equivalents, a finding that likely plays a significant role in the reduction of AF burden and recurrences. Hypertension and obesity are key mediators of atrial electrical and structural remodeling (4,5), with blood pressure lowering and weight loss likely contributing to the improved diastolic function, perhaps in tandem with exercise-induced changes. Although we fully agree that an improvement in LV diastolic function is an important factor in the antiarrhythmogenic benefits of exercise, the alliance of other risk factor changes, most notably reductions in blood pressure, body weight, and metabolic risk factors, clearly also improves AF outcomes in symptomatic, obese patients after lifestyle modification.
Network Resources Allocation in Content-Aware Networks for Multimedia Applications

— Virtual Content Aware Networks (VCAN) constructed as overlays over IP networks, are currently of high interest in the context of Future Internet multimedia distribution. The VCANs mapping onto real topologies while meeting some QoS properties is still an open issue and constitutes the objective of many studies. This paper continues a previous work which defined the management framework of a complex multi-domain networked media oriented system. Here it is proposed a combined set of algorithms and protocols to perform VCAN mapping on real network infrastructures both for intra and inter-domain, while meeting QoS constraints for multi-domain VCANs.
Survey on Zeta Converter Topology

This paper leads to the study of zeta converters and its future scope. Mainly it is analyzed for its induction into modular hybrid microgrid system. Here the main points of importance are design of zeta converters, its working, compatibility, feasibility etc. Apart from this our focus would be mainly on various research papers.
Moduli spaces of G 2 manifolds

This paper is a review of current developments in the study of moduli spaces of G 2 manifolds. G 2 manifolds are 7-dimensional manifolds with the exceptional holonomy group G 2 . Although they are odd-dimensional, in many ways they can be considered as an analogue of Calabi-Yau manifolds in 7 dimensions. They play an important role in physics as natural candidates for supersymmetric vacuum solutions of M -theory compactiﬁcations. Despite the physical motivation, many of the results are of purely mathematical interest. Here we cover the basics of G 2 manifolds, local deformation theory of G 2 structures and the local geometry of the moduli spaces of G 2 structures.
Performance Comparison of SDN Solutions for Switching Dedicated Long-Haul Connections

—We consider scenarios with two sites connected over a dedicated, long-haul connection that must quickly fail-over in response to degradations in host-to-host application performance. We present two methods for path fail-over using OpenFlow-enabled switches: (a) a light-weight method that utilizes host scripts to monitor the application performance and dpctl API for switching, and (b) a generic method that uses two OpenDaylight (ODL) controllers and REST interfaces. The restoration dynamics of the application contain signiﬁcant statistical variations due to the controllers, north interfaces and switches; in addition, the variety of vendor implementations further complicates the choice between different solutions. We present the impulse-response method to estimate the regressions of performance parameters, which enables a rigorous and objective comparison of different solutions. We describe testing results of the two methods, using TCP throughput and connection rtt as main parameters, over a testbed consisting of HP and Cisco switches connected over long-haul connections emulated in hardware by ANUE devices. The combination of analytical and experimental results demonstrates that dpctl method responds seconds faster than ODL method on average, while both methods restore TCP throughput.
Seasonal Sources of Whole-Lake CH4 and CO2 Emissions From Interior Alaskan Lakes

Thermokarst Abstract The lakes that form via ice ‐ rich permafrost thaw emit CH 4 and CO 2 to the atmosphere from previously frozen ancient permafrost sources. Despite this potential to positively feedback to climate change, lake carbon emission sources are not well understood on whole ‐ lake scales, complicating upscaling. In this study, we used observations of radiocarbon ( 14 C) and stable carbon ( 13 C) isotopes in the summer and winter dissolved CH 4 and CO 2 pools, ebullition ‐ CH 4 , and multiple independent mass balance approaches to characterize whole ‐ lake emission sources and apportion annual emission pathways. Observations focused on ﬁ ve lakes with variable thermokarst in interior Alaska. The 14 C age of discrete ebullition ‐ CH 4 seeps ranged from 395 ± 15 to 28,240 ± 150 YBP across all study lakes; however, dissolved 14 CH 4 was younger than 4,730 YBP. In the primary study lake, Goldstream L. , the integrated whole ‐ lake 14 C age of ebullition ‐ CH 4 , as determined by three different approaches, ranged from 3,290 to 6,740 YBP. A new dissolved ‐ 14 C ‐ CH 4 ‐ based approach to estimating ebullition 14 C age and ﬂ ux showed close agreement to previous ice ‐ bubble surveys and bubble ‐ trap ﬂ ux estimates. Differences in open water versus ice ‐ covered dissolved gas concentrations and their 14 C and 13 C isotopes revealed the in ﬂ uence of winter ice trapping and forcing ebullition ‐ CH 4 into the underlying water column, where it comprised 50% of the total dissolved CH 4 pool by the end of winter. Across
LITERATURE SURVEY ON DIGITAL IMAGE PROCESSING AND ITS TECHNIQUES

- Image processing is incredible significance these days. Face recognition becomes troublesome with regards to obscured and poorly enlightened images and it is here face recognition and reclamation comes to picture. In this paper, we survey numerous methods that were proposed in such manner and in this paper we will inspect various methods and technologies talked about up until now. The merits and demerits of various methods are talked about in this worry. This literature survey is to give an overall description on the different contemplations on the development and implementation of image/video quality appraisal system of image processing
COMPUTED TOMOGRAPHIC EVALUATION OF SEIZURES (EPILEPSY) IN PEDIATRIC AGE GROUP

: BACKGROUND AND OBJECTIVE: The study is aimed to reassess the role of CT in detecting various epileptogenic lesions with multi detector CT imaging, to know the value of CECT is evaluation of various lesions and to know the commonest CNS lesions causing afebrile seizures in Paediatric age group is the local population. METHODOLOGY: The study consists of 70 Pediatric patients suffering from afebrile seizures referred to Radio – diagnostic department S.V. R.R. Hospital at Tirupati for C.T. brain investigation. EXCLUSION CRITERIA: As our study is to evaluate epilepsy characterized by recurrent (more than two episodes) seizures, with no immediate identifiable and avoidable cause (sleep deprivation), known metabolic disorders, alcohol withdrawal, pyrexia. Therefore we excluded patients below one month ago. Febrile convulsions, acute infections, toxic and known metabolic disorders Equipment used is Fourth generation Four slice CT with scan time 0.7 seconds Matrix size 640, gantry tilt 120, KV – 120 MAs – 100 to 200, Slice thickness 5mm and 2mm Auto power injector 3 to 3.5 ml per second. NECT: Continuous axial sections of brain, posterior fossa 3mm and rest of brain 5mm sections and 2mm sections were taken wherever necessary CECT is carried out logically in those cases which were inconclusive or ambiguous and NECT excluding more definite cases like congenital anomalies and calcified granulomas without peri lesion edema. IV CONTRAST: Non-ionic contrast medium at 1mg/ kg body weight was used whenever indicated, no adverse reactions were noted after injection of contrast medium and sedation was advised whenever the patient was un co-operative. RESULTS: In the present study we evaluated to cases of Pediatric Seizures observed and analyzed our findings with the available relevant clinical data and concluded 70 cases are a Slight female Predilection 57%. maximum no useful CECT is may not play any role in evaluation of most of the congenital anomalies and calcified lesions. Ring enhancing lesions of infections etiology especially NCC are the commonest epileptogenic foci in our local paediatric population. Therefore CT is the prime mode of investigation is evaluation of epilepsy in Paediatric
Content Delivery Architecture for Communication Device-to-Device Wireless Networks

—The Device to Device (D2D) communications have become essential in daily life. Current technologies characteristics preclude the transparent exchange of content among devices. To address this, an architecture that manages the Wi-Fi interface device is deﬁned. It promotes communication between devices, allowing transparent content exchange without user intervention. Two applications that employ the use of this architecture are presented. The ﬁrst one, for personal devices, proved to be scalable in tests with up to nine devices. The second one, for vehicles, proved to be feasible when applied in scenarios with low speed, causing a low packet loss and high transmission rates.
Institutional Knowledge at Singapore Management University Institutional Knowledge at Singapore Management University Two-Layer Multiple Kernel Learning Two-Layer Multiple Kernel Learning

Multiple Kernel Learning (MKL) aims to learn kernel machines for solving a real machine learning problem (e.g. classiﬁcation) by exploring the combinations of multiple kernels. The traditional MKL approach is in general “shallow” in the sense that the target kernel is simply a linear (or convex) combination of some base kernels. In this paper, we investigate a framework of Multi-Layer Multiple Kernel Learning (MLMKL) that aims to learn “deep” kernel machines by exploring the combinations of multiple kernels in a multi-layer structure, which goes beyond the conventional MKL approach. Through a multiple layer mapping, the proposed MLMKL framework of-fers higher ﬂexibility than the regular MKL for ﬁnding the optimal kernel for applications. As the ﬁrst attempt to this new MKL framework, we present a Two-Layer Multiple Kernel Learning (2LMKL) method together with two eﬃcient algorithms for classiﬁcation tasks. We analyze their generalization perfor-mances and have conducted an extensive set of experiments over 16 benchmark datasets, in which encouraging results showed that our method performed better than the conventional MKL methods.
Seismic Simulations Using Parallel Computing and Three-Dimensional Earth Models to Improve Nuclear Explosion Phenomenology and Monitoring

The development of accurate numerical methods to simulate wave propagation in three-dimensional (3D) earth models and advances in computational power offer exciting possibilities for modeling the motions excited by underground nuclear explosions. This presentation will describe recent work to use new numerical techniques and parallel computing to model earthquakes and underground explosions to improve understanding of the wave excitation at the source and path-propagation effects. Firstly, we are using the spectral element method (SEM, SPECFEM3D code of Komatitsch and Tromp, 2002) to model earthquakes and explosions at regional distances using available 3D models. SPECFEM3D simulates anelastic wave propagation in fully 3D earth models in spherical geometry with the ability to account for free surface topography, anisotropy, ellipticity, rotation and gravity. Results show in many cases that 3D models are able to reproduce features of the observed seismograms that arise from path-propagation effects (e.g. enhanced surface wave dispersion, refraction, amplitude variations from focusing and defocusing, tangential component energy from isotropic sources). We are currently investigating the ability of different 3D models to predict path-specific seismograms as a function of frequency. A number of models developed using a variety of methodologies are available for testing. These include the WENA/Unified model of Eurasiamore » (e.g. Pasyanos et al 2004), the global CUB 2.0 model (Shapiro and Ritzwoller, 2002), the partitioned waveform model for the Mediterranean (van der Lee et al., 2007) and stochastic models of the Yellow Sea Korean Peninsula region (Pasyanos et al., 2006). Secondly, we are extending our Cartesian anelastic finite difference code (WPP of Nilsson et al., 2007) to model the effects of free-surface topography. WPP models anelastic wave propagation in fully 3D earth models using mesh refinement to increase computational speed and improve memory efficiency. Thirdly, we are modeling non-linear near-source shock wave propagation with GEODYN, an Eulerian Godunov finite-difference code (Antoun et al., 2001). This code accounts for shock wave propagation and a variety of effects including cavity formation, rock fracture and plastic deformation. We are exploring the coupling of GEODYN to WPP to propagate motions from the near-source (non-linear) region to the (linear anelastic) region where seismic observations are made at local, regional and teleseismic distances. This effort has just begun and we show preliminary results in this paper (with more to follow in our poster). These simulation tools are supported by massively parallel computers operated by Livermore Computing. « less
Relationship between California Mastitis Test Scores and Somatic Cell Counts in Different Crossbred Dairy Cattle Genotypes

— The objective of this study was to evaluate relationship between California Mastitis Test scores (CMT) and Somatic Cell Counts in different crossbred dairy cattle genotypes. A total of 152 milk samples were screened for mastitis using the California Mastitis Test (CMT) kit. Somatic Cell Count (SCC) in milk samples were analysed directly using microscopic method. Based on the analysis of CMT score, the study found out that 55.92 % of udder quarters were negative while 43.99 % were positive for subclinical mastitis. The Least Square Difference (LSD) for pairwise comparison between CMT scores and lactation stage were significantly different between First and second lactation at 0.25±0.11; second and third at 0.27±0.0118 at P ≤ 0.05 . The means of SCC among the breeds were significantly different at P ≤ 0.05; Ayshires and Friesians (68,055±18.82 cells/ml); Ayshire and Guernsey (71,976±23.844 cells/ml); Friesians and Jerseys (64.863±21.429 cells/ml); and Guernsey and Jersey (68.78±25.952 cells/ml). In conclusion, this study provides baseline information in the area of selection for mastitis resistant breeds of dairy cattle. This study also strongly recommends the use of this technique in screening for somatic cell counts in udder quarters of crossbred dairy cattle.
Large space-time scale behavior of linearly interacting diffusions

This dissertation in mathematics is devoted to systems consisting of a countably infinite collection of diffusion processes with a linear attractive interaction. Such systems have been used in population biology as a stochastic model for the distribution of genes over a population, or for the size of a population at different places as a function of time. Three chapters treat the behavior of such systems as the time tends to infinity (large time scale behavior) as well as the behavior of the system when both time and space are rescaled (large space-time scale behavior). This behavior is shown to be universal in huge classes of models. Each individual diffusion process takes values in a compact and convex d-dimensional real space. The results generalize work by Dawson, Greven, Baillon, Clement, and Den Hollander who treated such questions for 1-dimensional space. The theorems hang on a condition involving the harmonic functions of the diffusion processes, which is formulated in chapter 3. This means that the results apply only to diffusions of Wright-Fisher type and to isotropic diffusions. The dissertation contains an introduction explaining the origin of the models and an appendix on diffusion theory.
Title : The NOD / RIP 2 Pathway Is Essential for Host Defenses Against Chlamydophila pneumoniae Lung Infection

Here we investigated the role of the Nod/Rip2 pathway in host responses to Chlamydophila pneumoniae–induced pneumonia in mice. Rip2 mice infected with C. pneumoniae exhibited impaired iNOS expression and NO production, and delayed neutrophil recruitment to the lungs. Levels of IL-6 and IFN-c levels as well as KC and MIP-2 levels in bronchoalveolar lavage fluid (BALF) were significantly decreased in Rip2 mice compared to wild-type (WT) mice at day 3. Rip2 mice showed significant delay in bacterial clearance from the lungs and developed more severe and chronic lung inflammation that continued even on day 35 and led to increased mortality, whereas WT mice cleared the bacterial load, recovered from acute pneumonia, and survived. Both Nod1 and Nod2 mice also showed delayed bacterial clearance, suggesting that C. pneumoniae is recognized by both of these intracellular receptors. Bone marrow chimera experiments demonstrated that Rip2 in BM-derived cells rather than non-hematopoietic stromal cells played a key role in host responses in the lungs and clearance of C. pneumoniae. Furthermore, adoptive transfer of WT macrophages intratracheally was able to rescue the bacterial clearance defect in Rip2 mice. These results demonstrate that in addition to the TLR/MyD88 pathway, the Nod/ Rip2 signaling pathway also plays a significant role in intracellular recognition, innate immune host responses, and ultimately has a decisive impact on clearance of C. pneumoniae from the lungs and survival of the infectious challenge. Citation: Shimada K, Chen S, Dempsey PW, Sorrentino R, Alsabeh R, et al. (2009) The NOD/RIP2 Pathway Is Essential for Host Defenses Against Chlamydophila pneumoniae Lung Infection. PLoS Pathog 5(4): e1000379. doi:10.1371/journal.ppat. 1000379 Editor: David S. Schneider, Stanford University, United States of America Received October 24, 2008; Accepted March 12, 2009; Published April 10, 2009 Copyright: 2009 Shimada et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Funding: This work was supported by National Institutes of Health grants AI 067995 and HL66436 to MA. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. Competing Interests: The authors have declared that no competing interests exist. * E-mail: moshe.arditi@cshs.org
Methicillin Resistant Staphylococcus Aureus : A Cause of Concern

Background: Staphylococcus aureus can cause superficial skin infections such as boils, furuncles, styes etc. to life threatening systemic illness like surgical site infections, meningitis, pneumonia, blood stream infections, osteomyelitis. Methicillin Resistant Staphylococcus aureus (MRSA) was first reported in 1961after 1 year of its clinical use. Presently MRSA is a major cause of Health care associated and community acquired infection worldwide. MRSA strains can readily develop resistance to most of the antimicrobials in clinical use. Methicillin resistance occurs mostly due to altered Penicillin binding protein (PBP2a) and mainly mediated by mec A gene. Cefoxitin resistance is a surrogate marker of mec A gene mediated Methicillin resistance. Aim: To detect the incidence of MRSA strains in our hospital and to study the antibiotic susceptibility profile of MRSA strains. Material & methods: 100 Staphylococcus aureus strains isolated from different clinical samples such as pus, blood, urine etc. were studied. Antibiotic susceptibility test was done by Kirby-Bauer disc diffusion method and Methicillin resistance was detected by using Cefoxitin 30μg disc as per CLSI Guidelines, 2016. Result: 56% Staphylococcus aureus strains were MRSA. All MRSA strains were sensitive to Vancomycin and Linezolid and resistant to Penicillin. Conclusion: Detection of MRSA strains should be done in Clinical Microbiology Laboratory for effective patients’ treatment and implementation of Infection Control measures in Health Care Setup to prevent its spread.
Inactivation of nuclear Wnt- (cid:2) -catenin signaling limits blastocyst competency for implantation

l of plasma obtained by retroorbital phlebotomy from pregnant females receiving empty or Dkk1 ADV using anti-His probe antibody (Santa Cruz Biotechnology) as previously described (Kuhnert et al., 2004). To further explore the consequence of Wnt inhibition on blastocyst implantation, we applied small-molecule inhibitors of the (cid:2) -catenin-Tcf complex, PKF115-584 and CGP049090 (Novartis) (Lepourcelet The activation of the blastocyst, a process by which it gains competency to attach with the receptive uterus, is a prerequisite for successful implantation. However, the molecular basis of blastocyst activation remains largely unexplored. Combining molecular, pharmacological and physiological approaches, we show here that silencing of Wnt- (cid:2) -catenin signaling in mice does not adversely affect the development of preimplantation embryos to blastocysts and uterine preparation for receptivity, but, remarkably, blocks blastocyst competency to implantation. Using the physiologically relevant delayed implantation model and trophoblast stem cells in culture, we further demonstrate that a coordinated activation of canonical Wnt- (cid:2) -catenin signaling with attenuation of the non-canonical Wnt-RhoA signaling pathway ensures blastocyst competency to implantation. These findings constitute novel evidence that Wnt signaling is at least one pathway that determines blastocyst competency for implantation.