Miracle-dz/UniFAR-FTUs huggingface dataset:
Organizational change management in industrial SMEs in the optimization of decision making

The research carried out in SMEs shows that to improve organizational processes, great developments have been achieved, but then, in an impact and follow-up study it was determined that there are high failure and retention rates of small and medium-sized enterprises, since, Improvements are not implemented or implemented with little effectiveness. Reason why, to solve this problem, organizational change must be studied and how these models are implemented or can be implemented in industrial SMEs. For this, different models of organizational change that SMEs employ are studied and compared with the organizational management implemented, to achieve a diagnosis and define the criteria and sub-criteria necessary for an AHP analysis methodology, with the results obtained, it is intended to establish a method that achieves the real change in SMEs
Moringa oleifera Leaves Protein Enhances Intestinal Permeability by Activating TLR4 Upstream Signaling and Disrupting Tight Junctions

Changes in intestinal mucosal barrier permeability lead to antigen sensitization and mast cell-mediated allergic reactions, which are considered to play important roles in the occurrence and development of food allergies. It has been suggested that protein causes increased intestinal permeability via mast cell degranulation, and we investigated the effect of camellia Moringa oleifera leaves protein on intestinal permeability and explored its role in the development of food allergies. The current study investigated the effect of M. oleifera leaves protein on intestinal permeability through assessments of transepithelial electrical resistance (TEER) and transmembrane transport of FITC-dextran by Caco-2 cells. The expression levels of Toll-like receptor 4 (TLR4), IL-8, Occludin, Claudin-1, and perimembrane protein family (ZO-1) were detected by real-time PCR and Western blotting. The effect of M. oleifera leaves protein on intestinal permeability was verified in mice in vivo. The serum fluorescence intensity was measured using the FITC-dextran tracer method, and the expression of tight junction proteins was detected using Western blotting. The results showed that M. oleifera leaves protein widened the gaps between Caco-2 cells, reduced transmembrane resistance, and increased permeability. This protein also reduced the mRNA and protein levels of Occludin, Claudin-1, and ZO-1. Animal experiments showed that intestinal permeability was increased, and that the expression of the tight junction proteins Occludin and Claudin-1 were downregulated in mice. This study shows that M. oleifera leaves protein has components that increase intestinal permeability, decrease tight junction protein expression, promote transmembrane transport in Caco-2 cells, and increase intestinal permeability in experimental animals. The finding that M. oleifera leaves active protein increases intestinal permeability suggests that this protein may be valuable for the prevention, diagnosis, and treatment of M. oleifera leaves allergy.
Evolução recente da distribuição de renda e da pobreza no Brasil rural

Since the 60s, the Demographic Census has revealed a high degree of social inequality in Brazil. The concentration of income, as measured by the Gini index, showed persistently high since then. After the year 2001, we note that the trend of stability is disrupted and the Gini index begins to show a downward trend. Given this scenario, this study aimed to analyze the factors that determine this new situation.
Insecticidal activity of botanicals and their effectiveness in insects and pests control

Agriculturists in low-income nations, particularly subsistence farmers, frequently use botanical insecticides. The soaring cost and scarcity of commercial insecticides frequently promote the use of them. The identification of botanicals with insecticidal abilities is typically from folklore. Several scientific investigations have been done over the years to ascertain the effectiveness and safety of various botanical principles. Consistent reviews of these investigations are needed to update knowledge and to develop a theoretical foundation for further studies. Thus, the effectiveness of evaluated botanicals as insecticides against acarids and insect pests in agriculture is the primary focus of this article.
Industriālo robotu viedo vadības metožu izpēte un izstrāde

Promocijas darbs saistīts ar industriālo robotu viedām vadības metodēm, to lietojumiem un apmācības stratēģijām. Īpaši izceļot efektīvu datu sagatavošanu, datorredzē balstītu robotu vadību, un apmācību izmantojot demonstrācijas. Darba galvenais mērķis ir izpētīt un attīstīt jaunas metodes minētajās jomās, tādējādi uzlabojot industriālo robotu potenciālo izmantošanu darbam dinamiskā vidē, kompleksu uzdevumu efektīvai un potenciālajam galalietotājam atvieglotai izpildei. Balstoties literatūras analīzes laikā identificētajās problēmās un izaicinājumos, darbā izstrādātas un novērtētas jaunas sintētisko datu ģenerēšanas metodes izmantošanai datorredzē balstītā robotu vadībā un pieeja robotu apmācībai izmantojot cilvēku demonstrējumus.
The MYST Family Histone Acetyltransferase SasC Governs Diverse Biological Processes in Aspergillus fumigatus

The conserved MYST proteins form the largest family of histone acetyltransferases (HATs) that acetylate lysines within the N-terminal tails of histone, enabling active gene transcription. Here, we have investigated the biological and regulatory functions of the MYST family HAT SasC in the opportunistic human pathogenic fungus Aspergillus fumigatus using a series of genetic, biochemical, pathogenic, and transcriptomic analyses. The deletion (Δ) of sasC results in a drastically reduced colony growth, asexual development, spore germination, response to stresses, and the fungal virulence. Genome-wide expression analyses have revealed that the ΔsasC mutant showed 2402 significant differentially expressed genes: 1147 upregulated and 1255 downregulated. The representative upregulated gene resulting from ΔsasC is hacA, predicted to encode a bZIP transcription factor, whereas the UV-endonuclease UVE-1 was significantly downregulated by ΔsasC. Furthermore, our Western blot analyses suggest that SasC likely catalyzes the acetylation of H3K9, K3K14, and H3K29 in A. fumigatus. In conclusion, SasC is associated with diverse biological processes and can be a potential target for controlling pathogenic fungi.
Primary Tracheobronchial Amyloidosis Presenting with an Upper Airway Obstruction

Abstract This is a case of localized primary tracheobronchial amyloidosis in a patient who presented with upper airway obstruction. Tracheobronchial amyloidosis is a type of localized bronchopulmonary amyloidosis that is frequently overlooked. It involves the deposition of amyloid protein on the tracheal and bronchial tissue, leading to progressive tracheal stenosis and airway obstruction that can be seen on imaging as a tracheal mass. Because of its significant diagnostic difficulty and therapeutic conundrum, it ought to be considered in the differential diagnosis of upper airway symptoms with an unknown etiology.
Evaluating the use of self-conditioning adhesive combined with dual curing resin cement as an endodontic sealer: An in vitro study.

Abstract Objectives To compare infiltration, sealing and microleakage in root dentin with a self-conditioning adhesive system combined with dual curing resin (resin-based cement) to a conventional epoxy-resin-based sealer using confocal microscopy imaging. Methods 26 roots were enlarged and disinfected. Dentin tubules of 24 teeth were labelled with a red fluorophore (Rhodamine B) (two samples served as controls). Root canal samples were sealed in group AH (n = 11) with a conventional sealer (AH Plus Root Canal Sealer, Dentsply DeTrey) and in group RC (n = 11) with a resin-based cement (Parabond combined with Paracore, Coltène). Roots were then sectioned horizontally and immersed in H2O2 to remove the Rhodamine B not fixed by the sealers. The empty dentin spaces were labeled with a green fluorophore (Fluorescein) enabling the evaluation of infiltration as well as microleakage by confocal microscopy. Two additional samples were fractured in vertical direction for observation under SEM. Results Group RC presented significantly more infiltration in the middle third than in the middle and apical thirds of group AH. Microleakage was significantly higher in group AH than in group RC. SEM images revealed more dentin plugs and a homogenous resin layer in group RC in contrast to group AH. Conclusion The resin-based cement revealed promising outcomes compared to a traditional epoxy resin based sealer. Key messages Infiltration and microleakage in infiltrated and sealed root dentin samples are higher in middle than apical root thirds. Root dentin infiltration and sealing with a self-conditioning adhesive system and a dual-curing resin cement revealed less microleakage than with an epoxy-resin-based sealer.
BIG DATA PROCESSING WITH APACHE SPARK

With the exponential growth of information, it is no surprise that we are in a period of history as the Information Age. The rapid growth of data has presented challenges regarding storage and processing technology. This article refers to Apache Spark, an ecosystem that provides many integrated technologies in Big Data processing, including machine learning libraries and data storage platforms. Apache Spark provides distributed data processing for open source applications, loading data in-memory and making operations for analyzing data of any size, with efficient support for popular programming languages like Java, Scala, R, and Python. The article aims to compare the superior computing power of Saprk compared to Hadoop and how to connect Spark with today's popular data processing tools such as the R language.
A Method for Skeletal Arsenic Analysis, Applied to the Chalcolithic Copper Smelting Site of Shiqmim, Israel

A method for analysis of skeletal remains for arsenic using inductively-coupled plasma mass spectrometry (ICP-MS) is presented. Skeletal arsenic analysis has the potential to identify individuals, groups and communities engaged in copper smelting. The analysis is applied to a preliminary study of Shiqmim, Israel, a Chalcolithic copper smelting community, to assess the usefulness of skeletal arsenic analysis in archaeological remains. The results from this pilot study suggest that it is possible to identify individuals who may have been involved in metal working activities in antiquity through the chemical analysis of human skeletal material. The results also point to the potential of using this method to identify metal workers in the archaeological record for other regions and temporal periods.
Microfossils and Precambrian–Cambrian boundary stratigraphy at Maldeota, Lesser Himalaya

Abstract An assemblage of problematical microfossils of Precambrian–Cambrian boundary age is redescribed from the Chert–Phosphorite Member, at the base of the Lower Tal Formation of Maldeota in the Lesser Himalaya of India. This assemblage has previously been ascribed to various ages, from Precambrian to Cretaceous, but is held by us to contain: Maldeotaia bandalica, Protohertzina anabarica group, trumpet-shaped elements, acicular elements A & B, ? Conotheca sp. , Ovalitheca cf. multicostata, allathecid sp. A, Barbitositheca ansata, Hexangulaconularia cf. formosa, Coleoloides aff. typicalis, Hyolithellus aff. insolitus, H. cf. isiticus, H. vladimirovae, Spirellus shankari and Olivooides multisulcatus. These compare closely with assemblages found above the base of the first, Anabarites trisulcatus–Protohertzina anabarica Zone in China and in the second, Pseudorthotheca costata Zone of southern Kazakhstan. The stratigraphic setting of the Krol–Tal succession is reviewed and several similarities are noted between the Precambrian–Cambrian boundary successions of Lesser Himalaya in India and of Yunnan and Sichuan in Southwest China, indicating that correlation between them is possible at several levels.
Long-Term Feeding of Dairy Goats with 40% Artichoke by-Product Silage Preserves Milk Yield, Nutritional Composition and Animal Health Status

Simple Summary The rational use of agriculture and agro-industrial by-products in ruminant nutrition contributes to greater respect for the environment in addition to a better final product quality. Artichoke crops are widespread in the Mediterranean region but mostly not properly valued. Previous studies carried out with artichoke by-product silage at 25, 40 and 60% inclusion in dairy goat feed for one month showed that 40% inclusion would be a good option without any harm to milk yield and composition or animal health status. Therefore, it is worth studying the effect of feeding animals with 40% artichoke by-product silage during a full lactation period. No negative effects were observed on animal performances and productivity, allowing us to reduce agroindustry wastes and offering a long-term preserved by-product that promotes a sustainable circular economy and the production of animal products with high nutritional value, like goat milk. Abstract The aim of this work is to study the effect of 40% inclusion of artichoke by-product silage (AB) in dairy goat diets on milk yield, composition and animal health status during a full lactation period compared to an isoenergetic and isoproteic mixed ration based on alfalfa hay and a cereal and legume mixture. Milk yield was not affected by the dietary treatments, and neither was body weight. AB treatment reduced whey protein (0.38 vs. 0.42%, p < 0.05) and milk urea concentrations (687 vs. 773 mg/L, respectively, p < 0.001), and did not affect total true protein (3.22 vs. 3.24% p > 0.05) or other macro-composition variables. AB treatment showed higher milk concentrations of Ca (p < 0.05), Mn (p < 0.01), Cu (p < 0.01) and Zn (p < 0.001) compared to the control group (C). Slight differences were observed in milk fatty acid profile without any negative effects (p > 0.05) on the blood cholesterol and glucose of goats. The AB group reduced blood urea due to its high dietary total phenol content. However, it had a positive effect on β-hydroxybutyrate (p < 0.05) and nonesterified fatty acids (p > 0.05). It was concluded that 40% artichoke by-product inclusion in dairy goat feed for the whole lactation period (23 weeks) is a sustainable solution, reducing feeding cost by 12.5% per kg of dry matter, contributing to a better circular economy without any negative repercussions on the productivity and health of Murciano–Granadina dairy goats.
The State of the Art on Graphene-Based Sensors for Human Health Monitoring through Breath Biomarkers

The field of organic-borne biomarkers has been gaining relevance due to its suitability for diagnosing pathologies and health conditions in a rapid, accurate, non-invasive, painless and low-cost way. Due to the lack of analytical techniques with features capable of analysing such a complex matrix as the human breath, the academic community has focused on developing electronic noses based on arrays of gas sensors. These sensors are assembled considering the excitability, sensitivity and sensing capacities of a specific nanocomposite, graphene. In this way, graphene-based sensors can be employed for a vast range of applications that vary from environmental to medical applications. This review work aims to gather the most relevant published papers under the scope of “Graphene sensors” and “Biomarkers” in order to assess the state of the art in the field of graphene sensors for the purposes of biomarker identification. During the bibliographic search, a total of six pathologies were identified as the focus of the work. They were lung cancer, gastric cancer, chronic kidney diseases, respiratory diseases that involve inflammatory processes of the airways, like asthma and chronic obstructive pulmonary disease, sleep apnoea and diabetes. The achieved results, current development of the sensing sensors, and main limitations or challenges of the field of graphene sensors are discussed throughout the paper, as well as the features of the experiments addressed.
The perceived role fit of women and men academics: evidence from the social sports sciences

Introduction The underrepresentation of women in academia is often explained by the presence of gender stereotypes and the perception that women fit the role of an academic to a lesser extent. Based on social role theory and role congruity theory, this study investigates and estimates the perceived role fit of women and men academics in the social sports sciences. Methods Data were collected with a quantitative online survey. The sample (n = 792) includes individuals who study or work in sports economics, sport management, or sport sociology (referred to as social sports sciences). The questionnaire included items that reflect attributes of an ideal-typical academic as well as women and men academics in four dimensions, i.e., leadership, research methods, media visibility, and research topics. In the first step, these items were used to estimate a total role fit index for both women and men academics, as well as indices for all dimensions. In a second step, regression analyses were used to examine how respondents' individual characteristics (e.g., discipline, career stage, gender, presence of role models) are related to their perceived role fit indices and the differences in the perceived role fit. Results and discussion The role fit index ranges from 0 to 1, and women have a higher total role fit than men (0.77 vs. 0.75). The results suggest that women in the social sports sciences are perceived as a better fit for the role of an academic. In contrast to role congruity theory, women's leadership fit is higher than men's fit in this dimension (0.79 vs. 0.72). Regarding the associations of individual characteristics, professors seem to perceive a lower role fit for both genders than students. Furthermore, the difference between the perceived role fit of men and women is smaller for women respondents. Having a woman role model leads to a higher fit of women academics in the leadership dimension.
3-D modeling of geologic maps from surface data

Recent discoveries in earth sciences are mostly related to technologies allowing graphical representations of volumes. We present a way to produce mathematically and geometrically correct three-dimensional (3-D) geologic maps consisting of the volume and shape of all geologic features of a given area. The method is innovative in that it only uses surface information based on the combination of a standard geologic map, a satellite image, and a digital elevation model. It is based on a modeling algorithm that only uses surfaces calculated from scattered data points and that intersects them following a series of geologically sound rules. The major advantage of using such technology is that it provides the user with a way to quantify geology. To illustrate how a 3-D geologic map can be computed, we explain the steps taken to build a dummy model with simple faulting and depositional sequencing. The case study chosen to illustrate the method is the Beirut watershed (Lebanon), an area with relatively simple geology. The 3-D visualization and cross sections help in the understanding of the geometrical relationship between the different geologic features, allowing a reexamination of the tectonic history of the area during the late Mesozoic.
A literature study of human activities and pressures as well as ecosystem component layers available for Marine Spatial Planning and mapping of cumulative impacts in Swedish marine waters

We report a literature study on the needs for and the availability of data layers required for evidence-based Marine Spatial Planning (MSP) as well as mapping of the potential cumulative effects of multiple human activities. Specific focus is on data layers representing a variety of human activities and pressures as well as data layers representing ecologically-relevant species, habitats and communities. The aim of the study is to provide guidance for the Swedish SYMPHONY initiative and process, which ultimately is planned to result in a Swedish national data-driven ‘system’ for MSP and mapping of cumulative effects (Cumulative Effect Assessments; CEA). With this report and its conclusions and recommendations, the Swedish Agency for Marine and Water Management (SwAM) now holds the sufficient information required to – step by step – develop a nation-wide framework supporting evidence-based MSP and CEA. The crucial first step in this process is the build-up of an ecologically-relevant catalogue of pressure layers and ecosystem component layers. 4 keywords, Danish 4 keywords, English 1. Menneskelige aktiviteter og påvirkninger 1. Human activities and pressures 2. Økosystemkomponenter 2. Ecosystem components 3. Marin arealforvaltning 3. Marine Spatial Planning 4. Sverige 4. Sweden Jesper Andersen Nikolai Friberg Chief Scientist Research Director ISBN 978-82-577-6732-7 Science-based consultancy A literature study of human activities and pressures as well as ecosystem component layers available for Marine Spatial Planning and mapping of cumulative impacts in Swedish marine waters Client: Swedish Agency for Marine and Water Management NIVA Denmark Water Research 6997-2016
Health impact assessment of surface ozone pollution in Shanghai.

Based on the monitoring data of surface ozone in Shanghai in 2008,the daily maximum 8h(11:00～18:59)concentrations were averaged to represent the population-level ozone exposure level.All fixed residents living in Shanghai were the supposed affected population.In 2008,the annual average 8h maximum ozone concentration was 88μg/m3,and the ozone level in the central urban areas was lower than that in suburban areas (78μg/m3 versus 96μg/m3 respectively). It was estimated that 1892 (95% confidence intervals,95%CI:589～3540) premature deaths and 26049 (95%CI:13371～38499) cases of hospital admission were attributable to surface ozone pollution in 2008 in Shanghai.The corresponding economic loss of ozone-related health impacts was roughly 3.24 (95%CI:1.08～5.92) billion Yuan,88.12% of which was due to premature deaths.Our analysis suggests that the surface ozone pollution has brought substantial health and economic loss to Shanghai residents.
Simulation numérique d'un écoulement turbulent à masse volumique variable

Ce travail présente les résultats d’une étude numérique d’un écoulement bidimensionnel en jets coaxiaux à densité variable, obtenus par simulation numérique et réalisés par le logiciel de la dynamique des fluides Fluent (CFD). Ces résultats sont comparés avec d’autres résultats numériques et expérimentaux, où il a été montré que pour une distance axiale de X/Di < 6.88 apparait une transition de comportement du jet coaxial à un jet rond dans la zone initial, et pour X/Di > 6.88 le jet coaxial épouse un comportement similaire à celui d’un jet simple. On montre aussi qu’une zone de recirculation apparait quand le rapport de quantité de mouvement M est supérieur à la valeur de 64 à la position X/Di = 0.5 marquée par des vitesses négatives indiquant le retour du fluide vers l’arrière. Dans le cas hétérogène, le jet est plus large et plus rapide puisque l’hélium est plus léger que l’air, donc il possède un entraînement plus important.