Miracle-dz/UniFAR-FTUs huggingface dataset:
Análise dos fatores determinantes da estrutura de capital das empresas do setor de construção civil: Uma abordagem durante e após a crise imobiliária

Field studies in the area of corporate finance this increasingly widespread, requiring a highly qualified companies like item to continue operating in the market. In this sense, this study aims to verify possible determinants of capital structure of Brazilian public companies, the construction industry, a comparative analysis between the period of the global financial crisis of 2008 (2007 to 2010) and subsequent to the crisis (2011-2013) period. The evaluation is done by econometric and method of multiple linear regression, which includes a database of 18 companies in the sector listed on the BM&FBOVESPA.The results show that the crisis impacted the management of the capital structure of companies in the sector, having in that moment of crisis all covariates were significant, in which only the operating profit and size, were statistically significant. In the post-crisis period, only the profitability and risk were statistically significant coefficients with the same sense of relationship envisaged.
A Case of Non-cirrhotic Portal Hypertension With Antiphospholipid Syndrome

Nodular regenerative hyperplasia (NRH) and obliterative portal venopathy (OPV) are two causes of non-cirrhotic portal hypertension (NCPH), which is a vascular liver disease wherein clinical signs of portal hypertension (PHT), such as esophageal varices, ascites, and splenomegaly develop in the absence of cirrhosis and portal vein thrombosis. The etiology often remains unidentified, but herein we present the case of a 56-year-old male with NCPH and refractory ascites who underwent liver biopsy confirming NRH and OPV. Etiological workup revealed beta-2 glycoprotein-1 and anticardiolipin antibodies, concerning antiphospholipid syndrome (APS) despite no prior history of thrombosis. The patient underwent a transjugular intrahepatic portosystemic shunt (TIPS) procedure for his refractory ascites and was started on prophylactic anticoagulation owing to a concern for APS with clinical improvement in his ascites and shortness of breath. Pursuing TIPS earlier in the setting of refractory ascites, as well as offering anticoagulation therapy for patients with possible APS to prevent the development of potential thromboses, could be appropriate recommendations to prevent complications in the disease course. This case report highlights the need for further investigations on the etiologies, diagnosis pathways, and treatment options for NCPH.
Phenotype-Environment Matching Predicts Both Positive and Negative Effects of Intraspecific Variation

Natural populations can vary considerably in their genotypic and/or phenotypic diversity. Differences in this intraspecific diversity can have important consequences for contemporary ecological dynamics, but the direction and magnitude of these effects appear inconsistent across studies and systems. Here we proposed and tested the hypothesis that context-dependent ecological effects of altering phenotypic variance are predictable and arise from the relationship between a population’s mean phenotype and the local environmental optimum. By factorially manipulating the mean and variance of a key host trait in environments with and without a lethal parasite, we demonstrate that increasing phenotypic variance can have beneficial effects for host populations (e.g., smaller disease epidemics) but only when the population’s initial phenotype was poorly matched to the local environment. When phenotypes were initially well suited to environmental conditions, in contrast, greater phenotypic variance led to larger disease epidemics. Significant reductions in individual susceptibility occurred in both contexts over time, but the mechanisms leading to those reductions differed; strong selection was caused by either a suboptimal trait mean and insufficient trait variance or a near-optimal trait mean and too much trait variance. Increasing intraspecific variation is clearly not always beneficial for populations, instead producing predictable ecological and evolutionary effects that depend on environmental context and biological interactions.
Efficiency Index Diagram for Wake Region Evaluation of Artificial Reefs Facilitated for Marine Forest Creation

Recently, artificial reefs (ARs) have been frequently used primarily owing to the development in AR materials and projects for relatively complicated, large ARs. Among several engineering issues of ARs, wake region of an AR has been characterized because these regions have a high probability of recruiting seaweed spores, providing an energy saving zone, and facilitating deposition of sediments, nutrients, and bio-deposits. To characterize an efficiency index of an AR wake region and its dependency on the prevailing water flow directions, this study proposes a so-called efficiency index diagram. This characterization is done by normalizing the wake volumes with respect to the real AR volume and illustrating how efficiency indices vary with respect to the inlet flow directions. As a result, according to the diagram characteristics such as an averaged efficiency index, fundamental symmetric angle, secure angles, and principal directions, we can easily figure out how a target AR should be aligned along the main water flows to maximize the wake region around the AR. In addition, six ARs are considered and their efficiency index diagrams are illustrated to pinpoint the physical characteristics. for evaluating free shear and non-wall bounded flow behav-ior. To increase the numerical precision, the maximum element size near the ARs was limited to 10 or 20mm, depending on the element location. The water temperature, density, and dynamic viscosity are 25°C, 997 kg/m 3 , and 8.899×10 -6 kg m -1 s -1 , respectively. It should be noted here that the variation of water temperature, density, and dynamic viscosity does not give a major effect on the wake volume size (Le, 2016). Le (2016) showed that wake volumes according to water temperature (24 and 29°C) are almost identical.
Improved oncological treatment of anal cancer

AbstractBackground: Squamous cell cancer of the anus (SCCA) is a rare malignancy, but the incidence is increasing. It isassociated with humman papilloma virus infection. The standard treatment is radiotherapy (RT) combined withchemotherapy, usually 5-fluorouracil (5FU)/Mitomycin C (MMC). This treatment is relatively effective, butrecurrence still represents a problem especially in locally advanced SCCA.The overall aim of this thesis was to improve the treatment of SCCA by analysing a large Nordic population-basedcohort and to explore a new treatment strategy in a prospective phase I study, NOAC 8.Methods: Studies I-III were based on a retrospective cohort comprising 1266 patients with SCCA treatedaccording to Nordic guidelines between 2000 and 2007 (cohort 1), with definitive RT, alone or combined withchemotherapy (CRT), stratified by tumor stage.The second cohort included 13 patients with locally advancedSCCA enrolled in the NOAC 8 trial, investigating RT combined with cetuximab and 5FU/MMC, a combination thathad not been tested before. The primary aim was to determine the maximum tolerated dose (MTD) ofchemotherapy using a pre-defined dose escalation scheme.Results: High age, male gender, large primary tumor, lymph node metastases, distant metastases, poorperformance status and non-inclusion into a protocol were all independent factors associated with worseoutcome.The treatment results were good, well in accordance with published randomized trials. A high incidence(11%) of inguinal lymph nodes recurrence was observed in patients with small tumors where adjuvant lymphirradiation was omitted. Surgery alone of early SCCA was associated with a high locoregional recurrence rate andpoor survival, which were significantly improved with postoperative RT/CRT.The outcome in patients withmetastatic SCCA was poor, but it was significantly better in patients receiving active treatment. Male gender,metachronous disease and multiple metastatic sites were identified as prognostic factors associated with worseprognosis.The MTD of 5FU/MMC in combination with cetuximab and RT was determined.Dose limiting toxicity werediarrhoea, febrile neutropenia and thrombocytopenia.Conclusions: Good treatment results were obtained with widely implemented Nordic guidelines. We recommendprophylactic inguinal lymph node irradiation also for small tumors. Postoperative RT/CRT is effective after primarysurgery for early SCCA. The addition of cetuximab to 5FU/MMC in combination with RT was a rather toxicregimen but the side-effects were manageable. (Less)
The Role of Immune Cells Driving Electropathology and Atrial Fibrillation

Atrial fibrillation (AF) is the most common progressive cardiac arrhythmia worldwide and entails serious complications including stroke and heart failure. Despite decades of clinical research, the current treatment of AF is suboptimal. This is due to a lack of knowledge on the mechanistic root causes of AF. Prevailing theories indicate a key role for molecular and structural changes in driving electrical conduction abnormalities in the atria and as such triggering AF. Emerging evidence indicates the role of the altered atrial and systemic immune landscape in driving this so-called electropathology. Immune cells and immune markers play a central role in immune remodeling by exhibiting dual facets. While the activation and recruitment of immune cells contribute to maintaining atrial stability, the excessive activation and pronounced expression of immune markers can foster AF. This review delineates shifts in cardiac composition and the distribution of immune cells in the context of cardiac health and disease, especially AF. A comprehensive exploration of the functions of diverse immune cell types in AF and other cardiac diseases is essential to unravel the intricacies of immune remodeling. Usltimately, we delve into clinical evidence showcasing immune modifications in both the atrial and systemic domains among AF patients, aiming to elucidate immune markers for therapy and diagnostics.
Model-based compressive sensing for multi-party distant speech recognition

We leverage the recent algorithmic advances in compressive sensing, and propose a novel source separation algorithm for efficient recovery of convolutive speech mixtures in spectro-temporal domain. Compared to the common sparse component analysis techniques, our approach fully exploits structured sparsity models to obtain substantial improvement over the existing state-of-the-art. We evaluate our method for separation and recognition of a target speaker in a multi-party scenario. Our results provide compelling evidence of the effectiveness of sparse recovery formulations in speech recognition.
The Impact of Qinghai-Xizang Plateau Uplift on Asian General Circulation in Spring and Summer

To study the effects of the uplift of Qinghai-Xizang Plateau(QXP) on Asian atmospheric general circulation in spring and summer,the experiments with and without QXP are performed respectively(called TP-Experiment and NTP-Experiment hereafter) for 10 years using an atmospheric general circulation model with rhomboidal truncation(R42L9). Comparing the results of TP Experiment with NTP-Experiment,it is showed that the Asian atmospheric general circulation has a strong response to the uplift of QXP.The QXP split the westerlies and force them to flow around it in lower level.There are two branches of the westerlies,one flow to the north and the other to the south of the Plateau.The northern branch strengthen cold air go down southward to Eastern Asia.The intensity of southern branch enhances because of weaken heating of the QXP in spring.The enhanced southern branch transport moisture to southernChina.Meeting of cold and warm air in southern China causes heavy rain in there in spring.In summer,cyclonic circulation caused by the QXP strong heating source in lower level enhances the Eastern Asia summer monsoon on the east side of QXP and make it develop northward.However,the sensible heat air pumping of QXP bring negative vorticity and divergence over southern Asia in lowew level,and decrease the precipitation in there in summer.So the southern Asia summer monsoon weakens with the uplift of QXP.Another thermal influence of the QXP is reflected in upper level.The negative vorticity sources over the Plateau generated by the QXPheatingstrengthen the Iranhigh at 200 hPa in a remote way.
An Efficient Opportunistic Routing Protocol in Underwater Communication

For many years, opportunistic networks have gain fame in research and industry as a natural evolution of mobile ad hoc networks (MANETs). It is a more common concept of delay tolerant networks, which opens a thrilling path for connecting nodes opportunistically and communicates wirelessly and at the similar time expands the possibilities for real-life application problems. Presented ad hoc routing protocols, although robust to quickly changing network topology, suppose the being there of a connected path from source to destination. In this proposed system, we make a base station (BS1) on the upper layer of water. It is situated where signal strength is good. It will get the connection either by RSU (Road Side Unit) or by satellite. When it will get connected by RSU or satellite, sonar waves of base station amplifiers. Another base station (BS2) is situated under water at some distance from BS1 & gets radio waves by base station & its Sonar waves gets amplified.
Analytical method for electromagnetic coupling to a penetrated transmission line in cascaded multiple enclosures with hybrid apertures

An efficient analytical model has been developed for predicting the electromagnetic (EM) field coupling to a lossless transmission line (TL) penetrating through cascaded multiple rectangular enclosure with hybrid apertures (apertures with and without conductive sheets coexist) excited by an external plane wave of oblique incidence. First, The EM field in the enclosure through apertures covered by conductive sheets is derived using the dyadic Green’s function and the transfer impedance of the sheet. Then, the EM field in the enclosure through apertures without sheets is derived based on the Bethe’s small holes theory and the mirror procedure. Finally, the electric current induced at the TL terminals is obtained combining the equivalent lumped-pi circuit model of the TL and the Agrawal’s model. The analytical model has been successfully verified by the finite-difference time-domain (FDTD) method over the frequency range of 0.1 ~ 3 GHz, which consumes less time than numerical methods.
Recent Variation of Mass Balance of the Xiao Dongkemadi Glacier in the Tanggula Range and Its Influencing Factors

Glacier mass balance is the most direct and reliable parameter to reflect the status of a glacier.Based on the measured stakes/firn data from 2008 to 2012,the mass balance of the Xiao Dongkemadi Glacier was calculated.Combined with related meteorological data,the influence factors on the variation of mass balance were analyzed.The results showed that the glacier terminus retreated by 19.7 m from 2009 to 2012 with an average annual retreating ratio of 4.9 m,2.3 times of that in the middle and late 1990s.In the same time the equilibrium line altitude was 5 720 m,120 m higher than that in the early 1990s.Compared to that in 1995,the glacierized area shrunk 0.095 km2 and the terminus altitude rose 40 m.The mass balance was-1 584 mm w.e. ,equivalent to 1.76 m ice reduction,during the observing period.Particularly,in 2009/2010 the mass balance reached-996 mm w.e. ,the maximum negative mass balance throughout the whole observation period in the glacier.The higher summer air temperature and lower albedo caused by the pollution due to maintaining the Qinghai-Tibet Highway were the main reasons for this value.It is found that both air temperature,especially the summer air temperature,and the net radiation are the controlling factors of the mass balance.
Phytochemistry, Bioactivity, and Ethnopharmacology of the Genus Lepechinia Willd. (Lamiaceae): A Review

The genus Lepechinia (Lamiaceae) involves several aromatic shrubs that are distributed only in the American continent, inhabiting mountain areas, mainly in the Andean region of South America. Based on the PRISMA approach, we selected and critically analyzed 48 research articles. From a phytochemical point of view, most of the secondary metabolites reported in Lepechinia spp. are terpenes and terpenoids, with a few exceptions comprising flavonoids and other shikimic acid derivatives. On the one hand, sesquiterpenoids of the guajane, aromadendrane, eudesmane, and cadinane groups are characteristic of essential oils, together with (E)-β-caryophyllene as the main representative of its chemical family. On the other hand, abietane diterpenoids are the prevalent compounds described in non-volatile fractions. Many biological activities and traditional medical uses have been reported for both pure metabolites and complex mixtures (e.g., essential oils). Regarding ethno-medical uses, the treatment of muscle pain, headache, toothache, diabetes mellitus, uterine tumors, uterine infections, and diarrhea has been reported. Concerning their verified biological activities, insecticidal, antifungal, antioxidant, and anticholinesterase properties have been described. Furthermore, some data concerning anti-herpetic activity have been reported.
The Use of Nigella sativa in Cardiometabolic Diseases

Nigella sativa L. is an herb that is commonly used in cooking and in traditional medicine, particularly in Arab countries, the Indian subcontinent, and some areas of eastern Europe. Nigella sativa is also called “black cumin” or “black seeds”, as the seeds are the most-used part of the plant. They contain the main bioactive component thymoquinone (TQ), which is responsible for the pleiotropic pharmacological properties of the seeds, including anti-oxidant, anti-inflammatory, anti-hypertensive, anti-hepatotoxic, hypoglycemic, and lipid-lowering properties. In this narrative review, both the potential mechanisms of action of Nigella sativa and the fundamental role played by pharmaceutical technology in optimizing preparations based on this herb in terms of yield, quality, and effectiveness have been outlined. Moreover, an analysis of the market of products containing Nigella sativa was carried out based on the current literature with an international perspective, along with a specific focus on Italy.
The Role of Some Inflammatory Markers (IL-6 and CRP) in the Pathogenesis of Acute Coronary Syndrome in Iraqi CCU for Heart Diseases

In this work an enzyme linked immunosorbent assay (ELISA) technique has been used for detection of some inflammatory markers in serum of acute coronary syndrome (ACS)-Patients Admitted to the cardiac care unit (CCU) of Iraqi Centre For Heart Diseases and Ibn AlNafees Teaching Hospital. The present method includes quantitative measurement of interleukine-6 (IL-6) and C-reactive protein (CRP), as their increase during symptoms may be responsible for identifying the mechanism of myocardial damag, in addition to their best performance than other quantitative tests perhaps due to their association with atherosclerotic process that belongs to the endothelial dysfunction. Aim of this study is to estimate the prevalence and correlation of IL-6 with CRP in ACS- patients presented with unstable angina/ non-ST elevation myocardial infarction (UA/NSTEMI) symptoms to be as new diagnostic parameters in Iraqi CCU. Seventy (70) ACS- patients with mean age (58.55 year Â± 9.98), from Jun.2009 to Feb. 2010 with diagnosis of UA/NSTEMI were included in this study. Proper history, physical examination, electrocardiograph (ECG), and Echocardiography (ECHO) were performed for all patients in addition to the routine laboratory works including fasting blood glucose, lipid profile, assay of transaminases activity (Aspartate and Alanine transaminase),and biomarkers analysis as cardiac troponin I and T, creatine kinase (CK and CK-MB) and myoglobin. Blood sample was collected from all patients for quantitative assay of IL-6 and CRP. All patients underwent diagnostic coronary angiography, were 66 of them with abnormal coronary outcome and four patients have normal coronary arteries, study include 39- male and 31 female. Seventeen of 67 patients (25.4%) had elevated serum level of IL-6 and fifty four of 62 patients (87.1%) had elevated serum level of CRP. Statistically found strong and significant (SS) correlation between IL-6 and CRP (assessed by Spearman's rho correlation coefficient, P<0.01). The significant proportion of UA/NSTEMI patients that had elevated serum levels of IL-6 and/or CRP, in addition to the strong correlation with coronary angiographic findings make these inflammatory markers to be considered as risk stratification factors and good predictors for coronary artery disease independent of other traditional risk factors for cardiovascular disease (CVD). Key words: ACS. IL-6. CRP.
The world’s languages in crisis

“The world’s languages in crisis” (Krauss 1992), the great linguistic call to arms in the face of the looming language endangerment crisis, was first delivered in an Endangered Languages Symposium at the 1991 annual meeting of the Linguistic Society of America. Using the best available sources, he surveyed the global situation and estimated that only 10% of languages seem safe in the long term, up to 50% may already be moribund, and the remainder are in danger of becoming moribund by the end of this century. Twenty years later, better information is available. In this paper we use information from the latest edition of the Ethnologue (Lewis, Simons & Fennig 2013) to offer an update to the global statistics on language viability. Specifically the data for this study come from our work to estimate the level of every language on earth on the EGIDS or Expanded Graded Intergenerational Disruption Scale (Lewis & Simons 2010). Our finding is that at one extreme more than 75% of the languages that were in use in 1950 are now extinct or moribund in Australia, Canada, and the United States, but at the other extreme less than 10% of languages are extinct or moribund in sub-Saharan Africa. Overall we find that 19% of the world’s living languages are no longer being learned by children. We hypothesize that these radically different language endangerment outcomes in different parts of the world are explained by Mufwene’s (2002) observations concerning the effects of settlement colonization versus exploitation colonization on language ecologies. We also speculate that urbanization may have effects like settlement colonization and may thus pose the next great threat to minority languages.