Miracle-dz/UniFAR-FTUs huggingface dataset:
Affinely Adjustable Robust Bidding Strategy for a Solar Plant Paired With a Battery Storage

Due to green power generation, large solar plants with capacities in the order of several MWs are increasingly installed worldwide and plenty of these plants participate in electricity markets. However, the uncertain production of a solar plant poses a noticeable risk to the profit of a solar producer. To overcome the associated risk, storage systems have been recently paired with solar plants. Not only storage systems can increase the reliability of photovoltaic (PV) solar power, but also can increase economic benefits through energy arbitrage in an electricity market. Although paring a storage system with a solar plant is an economically promising combination, a proper bidding strategy model, which appropriately characterizes the uncertainties of both PV solar power productions and electricity prices, is essential. To do so, this paper proposes an affinely adjustable robust bidding strategy for a solar producer paired with a battery storage system. The uncertainties associated with solar power productions and electricity prices are characterized through bounded intervals in a controllable polyhedral uncertainty set. Affine functions are used to solve the proposed model directly without decomposition. Numerical results illustrate the effectiveness of the proposed method.
Large-Scale Human Immunodeﬁciency Virus Rapid Test Evaluation in a Low-Prevalence Ugandan Blood Bank Population (cid:1)

The use of rapid tests for human immunodeﬁciency virus (HIV) has become standard in HIV testing algorithms employed in resource-limited settings. We report an extensive HIV rapid test validation study conducted among Ugandan blood bank donors at low risk for HIV infection. The operational characteristics of four readily available commercial HIV rapid test kits were ﬁrst determined with 940 donor samples and were used to select a serial testing algorithm. Uni-Gold Recombigen HIV was used as the screening test, followed by HIV-1/2 STAT-PAK for reactive samples. OraQuick HIV-1 testing was performed if the ﬁrst two test results were discordant. This algorithm was then tested with 5,252 blood donor samples, and the results were compared to those of enzyme immunoassays (EIAs) and Western
Characterization of genomic clones specifying rabbit a- and f3-ventricular myosin heavy chains

We have isolated gene sequences coding for the a- and P-myosin heavy chains (HC) of rabbit ventricular muscle. A rabbit genomic library was screened with previously characterized cDNA clones specifying part of the light mero- myosin and the entire subfragment 2 portion of r- and fi-myoP sin HCs, as well as with a clone containing the 3' nontranslated sequences of the a-myosin HC mRNA. Seven strongly hybridizing clones were analyzed in detail. One genomic clone en-coded all of the 3' nontranslated sequences of an a-cDNA clone and, therefore, contained the 3 end of the a-myosin HC gene. Electron microscopic heteroduplex analysis and DNA sequence analysis showed that this clone overlapped a second genomic clone providing more than 25 kilobase pairs of the a- myosin HC gene. The exons within this region corresponded to -859% of the nmRNA and were separated by at least 28 introns. A clone for the ,-myosin HC gene was also identified by Southern blot hybridization, by heteroduplex' mapping, and by comparing the DNA sequence of a subfragment 2 exon to sequences of the a- and 13-cDNA clones. The introns of the a-and fi-myosin HC genes were in the same position but showed marked variation in length. These results conclusively showed that the a- and ,8-myosin HCs are products of separate genes.
White Matter Microstructural Damage in Small Vessel Disease Is Associated With Montreal Cognitive Assessment But Not With Mini Mental State Examination Performances Vascular Cognitive

were assessed. In univariate analyses, a significant association of both MoCA and mini mental state examination scores with age, education, cortical atrophy, and medial temporal lobe atrophy was found, whereas mean diffusivity and fractional anisotropy were associated with MoCA. In partial correlation analyses, adjusting for all demographic and neuroimaging variables, both mean diffusivity and fractional anisotropy were associated only with MoCA (mean diffusivity: r = −0.275, P =0.023; fractional anisotropy: r =0.246, P =0.043). Conclusions —In patients with mild cognitive impairment and small vessel disease, diffusion tensor imaging-measured white matter microstructural damage is more related to MoCA than mini mental state examination performances. MoCA is suited for the cognitive screening of patients with small vessel disease. ( Stroke . 2015;46:262-264. DOI: 10.1161/STROKEAHA.114.007553.)
Comparison of the clinical bene ts for non-small cell lung cancer patients between different volume of pleural lavage uid following video-assisted thoracoscopic lobectomy and systematic mediastinal lymph node dissection: study protocol for a randomized controlled trial

Jian Zhou Sichuan University West China Hospital Chengwu Liu Sichuan University West China Hospital Shulei Man West China School of Medicine Mengyuan Lyu Sichuan University West China Hospital Hu Liao Sichuan University West China Hospital Nan Chen Sichuan University West China Hospital Yuhui Cheng Sichuan University West China School of Medicine Lunxu Liu (  lunxu_liu@aliyun.com ) Sichuan University West China Hospital
Efficient TGF- (cid:12) /SMAD signaling in human melanoma cells associated with high c-SKI/SnoN expression.

Background: SKI and SnoN proteins have been shown to inhibit TGF- b signaling, acting both as transcriptional co-repressors in the cell nucleus, and as sequestrators of SMAD proteins in the cytoplasm. TGF- b , on the other hand, induces rapid, proteasome-mediated, degradation of both proteins. How elevated SKI and SnoN protein levels co-exist with active autocrine TGF- b signaling in cancer cells is yet to be understood. Results: In this study, we found elevated SKI and SnoN protein levels in a panel of melanoma cell lines, as compared to normal melanocytes. There was no correlation between SKI protein content and the capacity of melanoma cells to invade Matrigel ™ , to form subcutaneous tumors, or to metastasize to bone after intracardiac inoculation into nude mice. Nor did we find a correlation between SKI expression and histopathological staging of human melanoma. TGF- b induced a rapid and dose-dependent degradation of SKI protein, associated with SMAD3/4 specific transcriptional response and induction of pro-metastatic target genes, partially prevented by pharmacologic blockade of proteasome activity. SKI knockdown in 1205Lu melanoma cells did not alter their invasive capacity or transcriptional responses to TGF- b , and did not allow p21 expression in response to TGF- b or reveal any growth inhibitory activity of TGF- b . Conclusions: Despite high expression in melanoma cells, the role of SKI in melanoma remains elusive: SKI does not efficiently interfere with the pro-oncogenic activities of TGF- b , unless stabilized by proteasome blockade. Its highly labile nature makes it an unlikely target for therapeutic intervention.
Keys under doormats: mandating insecurity by requiring government access to all data and communications

Twenty years ago, law enforcement organizations lobbied to require data and communication services to engineer their products to guarantee law enforcement access to all data. After lengthy debate and vigorous predictions of enforcement channels “going dark,” these attempts to regulate security technologies on the emerging Internet were abandoned. In the intervening years, innovation on the Internet ﬂourished
and Block Interaction with Antigen Peptide Ligands That Bind IgM Antibodies

We have selected a peptide-display phage library on IgM Abs and identiﬁed a panel of phage-expressing peptides that bind to IgM Abs in general, but not to Abs of other classes. A synthetic peptide corresponding to one of the displayed peptide sequences also binds to IgM Abs. The peptides bind to both soluble pentameric Abs and to monomeric cell-surface IgM. The phage-displayed and synthetic peptides inhibit the binding of IgM Abs to Ag. These peptides may create confounding artifacts when IgM Abs are used for epitope mapping studies. Nonetheless, the peptides may have both experimental and therapeutic utility. The Journal of Immunology, 1999, 163: 826–833.
Determinants of Preventable Obesity: A Recent Outlook

Obesity has been declared an epidemic by World Health Organization (WHO). Overweight and obesity along with malnutrition are on increasing trend in developing as well as developed countries. Rise in obesity is very important risk factor of non-communicable diseases like hypertension, diabetes mellitus, dyslipidemia, ischemic heart disease, liver diseases and cancer with a high risk of mortality and morbidity. Etiology of obesity is multifactorial, involving a complex interaction among genetic, metabolic, hormonal and environmental factors. Obesity is a disease that can be prevented as well as cured.
Energy-Aware Grid Based Coverage Path Planning for UAVs

—The usage of Unmanned Aerial Vehicles (UAVs) for diﬀerent tasks has rapidly increased in recent years. An Unmanned Aerial Vehicle is an unpiloted aircraft that operates by remote control or onboard computers. This technology has become promising in providing new opportunities in many ﬁelds, such as smart agriculture, photogrammetry, remote sensing, wireless coverage, rescuing and many others. Control-ling the mobility of an Unmanned Aerial Vehicle while monitoring geographical zones is one of the most important problems. In this context, managing the ﬂight route by ﬁnding an optimal path that fully covers the Area of Interest with minimum energy consumption is one of the main challenges. In this work, we propose an algorithm to scan an area that reduces completion-time and energy consumption. It also ensures a complete coverage of the area. We consider an Area of Interest without obstacles and non-ﬂying zones.
Prospect for measuring the CP phase in the hττ coupling at the LHC

The search for a new source of CP violation is one of the most important endeavors in particle physics. A particularly interesting way to perform this search is to probe the CP phase in the hττ coupling, as the phase is currently completely unconstrained by all existing data. Recently, a novel variable Θ was proposed for measuring the CP phase in the hττ coupling through the τ ± → π ± π 0 ν decay mode. We examine two crucial questions that the real LHC detectors must face, namely, the issue of neutrino reconstruction and the eﬀects of ﬁnite detector resolution. For the former, we ﬁnd strong evidence that the collinear approximation is the best for the Θ variable. For the latter, we ﬁnd that the angular resolution is actually not an issue even though the reconstruction of Θ requires resolving the highly collimated π ± ’s and π 0 ’s from the τ decays. Instead, we ﬁnd that it is the missing transverse energy resolution that signiﬁcantly limits the LHC reach for measuring the CP phase via Θ.
Quantifying clinical narrative redundancy in an electronic health record.

OBJECTIVE Although electronic notes have advantages compared to handwritten notes, they take longer to write and promote information redundancy in electronic health records (EHRs). We sought to quantify redundancy in clinical documentation by studying collections of physician notes in an EHR. DESIGN AND METHODS We implemented a retrospective design to gather all electronic admission, progress, resident signout and discharge summary notes written during 100 randomly selected patient admissions within a 6 month period. We modified and applied a Levenshtein edit-distance algorithm to align and compare the documents written for each of the 100 admissions. We then identified and measured the amount of text duplicated from previous notes. Finally, we manually reviewed the content that was conserved between note types in a subsample of notes. MEASUREMENTS We measured the amount of new information in a document, which was calculated as the number of words that did not match with previous documents divided by the length, in words, of the document. Results are reported as the percentage of information in a document that had been duplicated from previously written documents. RESULTS Signout and progress notes proved to be particularly redundant, with an average of 78% and 54% information duplicated from previous documents respectively. There was also significant information duplication between document types (eg, from an admission note to a progress note). CONCLUSION The study established the feasibility of exploring redundancy in the narrative record with a known sequence alignment algorithm used frequently in the field of bioinformatics. The findings provide a foundation for studying the usefulness and risks of redundancy in the EHR.
Fracture effects in seismic attenuation images reconstructed by waveform tomography

We have investigated seismic waveform tomography to characterize fractures in petroleum reservoirs. Seismic reﬂection data are used in a frequency-domain inversion to reconstruct subsurface attenuation images. The images show fracture distributions, from which fracture density is estimat-ed. Fractures smaller than or equal to a half-wavelength of seismic act as single scatterers, producing images of strong attenuation ellipses and from which fracture density can be estimated. When fracture size approaches one wavelength, fracture orientation affects the attenuation image. Horizontal fractures act as individual reﬂectors and produce strong to-mographic attenuation images from which fracture density can be estimated. The strength of the attenuation image de-creaseswhenthefractureanglerelativetohorizontalincreas-es;verticalfracturesproducetheweakestattenuationimage.Consequently,theaccuracyoffracturedensitymeasure-mentsdecreaseswithincreasedfractureangleunlesswave-formtomographyincludesdifferentseismicmodesacquiredfromseveraldirections.
Driven to Death: Inhibition of Farnesylation Increases Ras Activity in Osteosarcoma and Promotes Growth Arrest and Cell Death

To improve cancer outcomes, investigators are turning increasingly to small-molecule medicines that dis-rupt vital signaling cascades, inhibit malignant growth, or induce apoptosis. One vital signaling molecule is Ras, and a key step in Ras activation is membrane anchoring of Ras through prenylation, the C-terminal addition of a lipid anchor. Small-molecule inhibitors of farnesyltransferase (FTI), the enzyme most often responsible for prenylating Ras, showed clinical promise, but development of FTIs such as tipifarnib has been stalled by uncertainty about their mechanism of action, because Ras seemed unimpeded in tipifarnib-treated samples. Interpretation was further complicated by the numerous proteins that may be farnesylated, as well as availability of an alternate prenylation pathway, geranylgeranylation. Initial observations of varied response by osteosarcoma cell lines to tipifarnib led us to evaluate the role of FTI in Ras signal alteration using osteosarcoma models. We describe our novel counterintuitive finding that endogenous Ras activity increases in osteosarcoma when farnesyltransferase is inhibited by either tipifarnib or short hairpin RNA. In response to tipifarnib, variable growth arrest and/or cell death correlated with levels of activated extracellular signal-regulated kinase (ERK) and p38 mitogen-activated protein kinase (MAPK). Sensitivity to tipifarnib treatment was shown by growth inhibition and by an increase in subdiploid cell numbers; cells with such sensitivity had increased activation of ERK and p38 MAPK. Because Ras must be prenylated to be active, our findings suggest that geranylgeranylated N-Ras or K-Ras B interacts differently with downstream effector proteins in sensitive osteosarcoma cells responding to tipifarnib, switching the balance from cell proliferation to growth inhibition. Mol Cancer Ther; 9(5); OF1 – 9. ©2010 AACR. Biotechnology). Horseradish peroxidase – labeled polyclonal anti-mouse Ig (1:5,000; BD Biosciences) was used as secondary antibody for antibodies listed above. Chemi-luminescent signal was detected by the Immobilon Western blotting detection system (Millipore). Densitometry values are relative to actin and are representative of three experiments.
Do competitive conditions affect introgression of transgenes from oilseed rape (Brassica napus) to weedy Brassica rapa? –A case study with special reference to transplastomic oilseed rape

Under the assumption that plastids are inherited uniparental maternally, F1-hybrid production on oilseed rape is the only transgene escape route when cultivating transplastomic oilseed rape. We investigated the F1-hybrid production on winter oilseed rape co-cultivated with weedy B. rapa at three plant densities and with two proportions between the two species. Thus, contrary to most studies on hybridisation between oilseed rape and B. rapa, this study was focused on hybridisation with oilseed rape as the maternal parent. The paternity of the oilseed rape progeny was assessed. In order to correlate hybridisation and plant competition, several fitness parameters were determined in oilseed rape mother plants. With higher density, the vegetative fitness per mother plant decreased significantly. The density only affected the abundance of F1-hybrids significantly (decrease) at the 1:1 proportion. As to the proportion, more B. napus plants in the field significantly decreased the production of F1-hybrids. More B. napus and less B. rapa also increased most biomass components significantly. Thus, B. rapa was a stronger vegetative competitor than B. napus, which affected both the vegetative and reproductive fitness in B. napus, and increased the hybridisation frequency. In conclusion, the proportion was apparently a more powerful environmental factor than the density, and it appears that hybridisation on B. napus is most likely at current field densities of B. napus and when B. rapa is an abundant weed.
Obese mice lacking iNOS are sensitized to the metabolic actions of PPAR γ agonism

Department of Anatomy and Physiology, Laval University, Lipid Research Unit, Laval University Hospital Research Center, and Laval Hospital Research Center, Québec, Québec, Canada, Molecular Nutrition Unit, Department of Nutrition and Biochemistry, University of Montreal and the Montreal Diabetes Research Centre, Centre Hospitalier de l'Université de Montréal, Montréal, Québec, Canada. Departments of Cell Biology and Medicine, Diabetes Research and Training Center, Albert Einstein College of Medicine, Bronx, New York 10461, USA. Touchstone Diabetes Center, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, 75390-8549, USA.
Grid Spider: A Framework for Data Intensive Research with Data Process Memoization Cache

—As computational power grow, the new ﬁeld of “Data Intensive Computation” has emerged in which vast amounts of data generated by radio telescopes, particle accelerators, electron microscopes, genomics and Earth observation equipment is processed. In most cases, once the data has been accumulated, it is not overwritten. It has also been observed that in many cases the very same software is used to pre-process the very same data, leading to identical results. To address these issues, we propose “Grid Spider”, a framework for data intensive scientiﬁc research which is optimized to avoid re-computation through the utilization of our ﬁle cache mechanism called “Data Process Memoization Cache” or DPM-Cache. This mechanism requires pre-processing applications to maintain referential transparency. Both the data and the application are registered with Grid Spider prior to processing, and for each execution of the application, Grid Spider records the history of the coupling of the application, the input data ﬁe, and the output data ﬁle. To evaluate Grid Spider, we have implemented “GEO Grid Spider II”, which is a framework within which geo-scientists can evaluate satellite data archives.
High Voltage Energy Harvesters

Green energy helps in reducing carbon emission from fossil fuel, harvesting energy from natural resources like wind to power consumer appliances. To date, many researches have been focusing on designing circuits that harvest energy from electromagnetic signals wirelessly. While it could be designed to be efficient, the generated power however is insufficient to drive large loads. Wind energy is highly available environmentally but development of small-scale energy harvesting apparatus aiming to extract significant power from miniature brushless fan has received limited attention. The aim of this chapter is to give audience an insight of different voltage multipliers used in energy harvester and knowledge on various circuit techniques to configure voltage multipliers for use in different high voltage applications. These include AC-DC converter, AC-AC converter and variable AC-DC converter.
Additive interaction of levetiracetam with lamotrigine in the mouse 6 Hz psychomotor seizure model – an isobolographic analysis Current Issues in Pharmacy and Medical Sciences

The aim of this study was to characterize the anticonvulsant effects of levetiracetam (LEV) in combination with lamotrigine (LTG – a second-generation antiepileptic drug), in the mouse 6 Hz psychomotor seizure model. Limbic (psychomotor) seizure activity was evoked in albino Swiss mice by a current (32 mA, 6 Hz, 3 s stimulus duration) delivered via ocular electrodes and isobolographic analysis for parallel dose-response relationship curves (DRRCs) was used to characterize the consequent anticonvulsant interactions between the drug combinations. Results indicated that LEV administered singly was associated with a DRRC that was parallel to that for LTG. With isobolography for parallel DRRCs, the combination of LEV with LTG at three fixed-ratios of 1:3, 1:1 and 3:1 exerted additive interaction. LEV combined with LTG exerted additive interaction in the mouse 6 Hz psychomotor seizure model. to Litchfield and Wil coxon [13]. The theo reti cally ad di tive ED 50 add val ues and their S.E. at the fixed-ratio com bi na tions of 1:3, 1:1 and 3:1 were also cal cu lated with this pro grammed spread sheet. All sta tis ti cal tests were per formed us ing com mer cially avail able Graph Pad Prism ver sion 4.0 for Win dows (Graph Pad Soft ware, San Di ego, CA, USA).
MOOD STATE, MOTIVATION AND IMPULSIVENESS AMONG STUDENTS PARTICIPATING IN YOUTH SCHOOL GAMES PARTICIPANTES DOS JOGOS ESCOLARES DA JUVENTUDE

The objective of the present study was to describe the mood state, motivation and impulsiveness of students participating in youth school games and to compare these variables between sexes. The research was cross-sectional, and the sample was composed of 147 students aged 12 to 17 years old (14.53±1.51 years; 51.70% of male participants). The following scales were used: 1) Brunel Mood Scale; 2) Motives for Physical Activity Measure – Revised, and 3) Impulsive Behavior Scale. For comparison between groups, the Mann-Whitney U test was used, and the effect size was calculated by means of Cohen’s d. The results showed that female students presented higher scores for anxiety, anger, confusion, depression, fatigue, lack of perseverance and premeditation. On the other hand, male students presented higher scores for appearance and health, seeming to be more motivated by extrinsic factors compared to females. Therefore, it is suggested that training strategies should be adapted by sex, in view of the respective characteristics.