Miracle-dz/UniFAR-FTUs huggingface dataset:
IAI CONFERENCE: The potential of banana fruit Ranggap (Musa paradisiaca var. Troglodytarum) as an excipient alternative to oral tablet dosage form

Introduction: Starch is one of the ingredients that has many benefits, including in the pharmaceutical field, especially as a pharmaceutical excipient in pharmaceutical formulations. Aim: This study aims to isolate, characterise, and formulate the starch of banana fruit (Musa paradisiaca var. Troglodytarum) into tablet dosage forms. Methods: The characteristics of the perceived banana starch can be said to be comparable to that of corn starch so that it is expected to be used as a source of starch which can be used as a pharmaceutical excipient. The starch of isolated banana fruit was used as a filler, binder, and crusher in the wet granulation method tablet formulations with concentrations of 2%, 3%, and 5%. Results: The physicochemical characteristics of starch isolated from banana fruit are considered to meet the requirements of pharmaceutical excipients required in the Handbook of Pharmaceutical Excipients 6th edition and the United States Pharmacopeia 32nd edition. Conclusion: Of the total formulas tested, tablets with binder content of banana starch 3%, 5% and 10% corn starch meet the tablet evaluation requirements.
Multihump thermo-reorientational solitary waves in nematic liquid crystals: Modulation theory solutions

The propagation of light-induced thermo-reorientational solitary waves in nematic liquid crystals is studied using numerical solutions of the full governing equations and variational approximations. These thermo-reorientational solitary waves form as the nonlocal refractive index response to extraordinarily polarized light beams is both self-focusing via the induced rotation of the constituent molecules and self-defocusing owing to the temperature increase through optical absorption. These competing nonlinearities can lead to the formation of one- and two-dimensional multihumped solitary and ring-shaped waves at high enough optical powers with a volcano profile on the plane transverse to propagation. The variational solutions for these self-localized structured beams are in remarkably good agreement with full numerical solutions of the governing equations.
Bienestar subjetivo en el Envejecimiento Activo

Estudios mostraron que el bienestar está ligado a factores diversos como condiciones de crianza, vínculos con parientes y amigos, tipo de actividades laborales, rasgos de personalidad, disponibilidad y utilización del tiempo libre, lugar donde se vive, acceso a parques, lugares de convivencia social, los niveles de seguridad, la tenencia de hijos y sus diferentes edades, los vínculos de pareja, la economía del hogar y personal, el marco macroeconómico, la distribución de los ingresos, el desempleo y la ocupación, el nivel de salud, la escala de valores que se posee, la disponibilidad de participación en tomas de decisiones a nivel político y más. El bienestar subjetivo afecta y marca fuertemente el grupo etario de 60 a 64 años, relacionado con los cambios propios de la etapa evolutiva en la que se introducen, el bienestar subjetivo en dicha etapa aparece equilibrado y tendiente al incremento y el nivel educativo de la persona mayor tiene una directa relación con el bienestar subjetivo experimentado, porque a medida que éste se incrementa tienen mayor posibilidad de alcanzar el bienestar. Evaluando 30 años de estudios, la definición de envejecimiento activo y con éxito, se siguen sosteniendo. Más allá de las diferencias en las definiciones y miradas encontradas en la literatura, hay que destacar un punto de encuentro en relación a la necesidad de superar las restricciones de los modelos basados en visiones determinadas por lo cultural y social, delimitándose a los lugares donde se han evaluado, y no universalmente, también destacar la intención de integrar criterios objetivos con la subjetividad de aquellos implicados, con modelos más inclusivos que den la oportunidad de envejecer dignamente a todas las personas por igual. Resaltando la necesidad de una solidaridad intergeneracional y aproximación a esta cuestión desde un proceso de enseñanza y aprendizaje durante el transcurso de toda la vida.
Catalytic cracking of scrap tire-generated fuel oil from pyrolysis of waste tires with zeolite ZSM-5

ABSTRACT Power generation without environmental impairment is a challenging task for humankind. Presently pyrolysis process using various catalysts is among the finest technologies for generating alternate energy. This research aims to explore the pyrolysis of discarded bus/truck tires with zeolite ZSM-5. A fixed-bed reactor was employed to pyrolyse scrap tires at a temperature range of 300–580°C. Furthermore, it investigates the temperature and catalyst-to-tire ratio impact on the evolved oils’ generation and composition. Density, kinematic viscosity, and gross calorific value of the obtained oil, are analysed. CT ratio has increased the gas generation but decreases oil production. Elemental analysis of pyrolytic liquid oil revealed carbon percentage increment and decrement of sulphur percentage when CT ratio was increased. FT-IR showed data revealed the strong presence of aromatic compounds and other valuable hydrocarbons in the upgraded pyrolytic oils. The pyrolytic oil showed provided a high calorific value of 40.38 MJ/kg, comparable to conventional diesel oil of 42 MJ/kg. GC-MS analysis identified a higher amount of o-xylene, toluene, naphthalene, and d-limonene in derived oil when the CT ratio of the process was increased from 0.1 to 0.25, denoting the capability of the evolved oil as an alternative energy source and value-added chemical substances.
Time Series Segmentation Using Neural Networks with Cross-Domain Transfer Learning

Searching for characteristic patterns in time series is a topic addressed for decades by the research community. Conventional subsequence matching techniques usually rely on the definition of a target template pattern and a searching method for detecting similar patterns. However, the intrinsic variability of time series introduces changes in patterns, either morphologically and temporally, making such techniques not as accurate as desired. Intending to improve segmentation performances, in this paper, we proposed a Mask-based Neural Network (NN) which is capable of extracting desired patterns of interest from long time series, without using any predefined template. The proposed NN has been validated, alongside a subsequence matching algorithm, in two datasets: clinical (electrocardiogram) and human activity (inertial sensors). Moreover, the reduced dimension of the data in the latter dataset led to the application of transfer learning and data augmentation techniques to reach model convergence. The results have shown the proposed model achieved better segmentation performances than the baseline one, in both domains, reaching average Precision and Recall scores of 99.0% and 97.5% (clinical domain), along with 77.0% and 71.4% (human activity domain), introducing Neural Networks and Transfer Learning as promising alternatives for pattern searching in time series.
Exploring School Leaders Communities of Practice and School Improvement

This case study describes a pilot professional development project in which school leaders met regularly in a community of practice to clarify each other’s identification of a problem of practice followed by development and implementation of a school improvement plan. Findings indicated positive perceptions of and engagement in the community of practice, revealing this process provided a platform for authentic feedback, reflective practice, and means to share ideas. Participants reported improved leadership behaviors associated with school improvement planning and implementation.
MOTEO: A Novel Multi-Objective Thermal Exchange Optimization Algorithm for Optimal Design of Truss Structures

In the present paper, a physics-inspired metaheuristic algorithm is presented to solve multi-objective optimization problems. The algorithm is developed based on the concept of Newtonian cooling law that recently has been employed by the Thermal Exchange Optimization (TEO) algorithm to efficiently solve single-objective optimization problems. The performance of the multi-objective version of TEO (MOTEO) is examined through bi- and tri-objective mathematical problems as well as bi-objective structural design examples. According to the comparisons between the MOTEO and several well-known algorithms, the proposed algorithm can provide quality Pareto fronts with appropriate accuracy, uniformity and coverage for multi-objective problems.
El Objetivo de Desarrollo Sostenible 8. La fetichización del empleo y el oxímoron del crecimiento sostenible e inclusivo

Este artículo se centra en analizar la problemática del Objetivo de Desarrollo Sostenible 8 relativo al crecimiento económico y el trabajo digno. Se describe el ODS 8 y se reflexiona sobre los conceptos de crecimiento y sus límites, así como sobre el trabajo y sus características. También se abordan las implicaciones en términos de inclusión social. Se destacan los retos que supone un crecimiento inclusivo, así como las limitaciones para su medición. Así, hay que ahondar en otros indicadores que midan el bienestar social y el cuidado ambiental. Por lo tanto, se aborda el ODS 8 desde una perspectiva crítica e interdisciplinar. El paradigma neoliberal productivista colisiona con la sostenibilidad ambiental y social. Para avanzar en el ODS 8 se necesita una “desfetichización” de la productividad económica, la ralentización de la maquinaria tiempo desde el punto de vista ecológico y la consideración de los aspectos sociales.
Decadal Timescale Correlations Between Global Earthquake Activity and Volcanic Eruption Rates

At the global scale, large tectonic earthquakes and volcanic eruptions are believed to be random and independent events. Here, we compare global time‐series of large earthquakes ( Mw≥ 7) and explosive volcanic eruptions (VEI ≥ 2) spanning 1960–2019. Both time‐series exhibit decadal timescale trends, over which annual earthquake and eruption rates vary by a factor of ∼ 2. Moreover, global seismic moment release is positively correlated with global eruption rate, with Monte Carlo permutation tests showing that this correlation is significant with a P ‐value of < 0.05. Although large earthquakes can trigger eruptions at nearby volcanoes, the magnitude of this effect is insufficient to cause the observed global correlation. Other mechanisms, such as triggering of distant eruptions (>1000 km) by earthquake‐induced dynamic stress changes, modulation of global earthquake and eruption rates by variations in Earth's rotational velocity, or natural synchronization of events over repeating cycles, are therefore required to explain the correlation.
Reliability Evaluation of Photovoltaic System Considering Inverter Thermal Characteristics

The reliable operation of photovoltaic (PV) power generation systems is related to the security and stability of the power grid and is the focus of current research. At present, the reliability evaluation of PV power generation systems is mostly calculated by applying the standard failure rate of each component, ignoring the impact of thermal environment changes on the failure rate. This paper will use the fault tree theory to establish the reliability assessment method of PV power plants, model the PV power plants working in the variable environment through the hardware-in-the-loop simulation system, and analyze the influence of the thermal characteristics of the inverter’s key components on the reliability of the PV power plant. Studies have shown that the overall reliability of bus capacitors, inverters, and PV power plants is reduced by 18.4%, 30%, and 18.7%, respectively, compared to when the thermal characteristics of bus capacitors are not considered. It can be seen that thermal attenuation has a great influence on the reliability of the PV power generation system.
Monitoring of Field Patrolling Efforts, Vietnam: Insights from a Forest Station in Pu Hu Nature Reserve

In the various protected areas such as nature reserves and national parks in Vietnam, ranger patrols are crucial for protecting forest resources against the increasing threats from fringe communities. Previous studies have investigated ranger patrol efforts (RPEs) in conservation areas using conventional measures in terms of illegal activities encountered, but there has been little research into indices related to RPEs in the field, both worldwide and particularly in Vietnam. This paper explores various indices of RPEs and other aspects of forest patrolling at a local level. The number of rangers and patrol-days strongly influences the distance walked and the number of patrol-hours. However, neither the rainy season nor the Lunar New Year festival had any significant effect on patrol efforts, nor was there any effect on the relative altitude covered or the speed of patrolling during the long Lunar New Year vacation. Management responsible for protecting forest areas needs to consider the full scope of rangers’ efforts and identify the qualities of motivated staff. Our findings suggested ways in which rangers’ capacity to promote conservation may be assessed in the future.
Peptidylglycine α‐amidating monooxygenase as a therapeutic target or biomarker for human diseases

Peptides play a key role in controlling many physiological and neurobiological pathways. Many bioactive peptides require a C‐terminal α‐amide for full activity. The bifunctional enzyme catalysing α‐amidation, peptidylglycine α‐amidating monooxygenase (PAM), is the sole enzyme responsible for amidated peptide biosynthesis, from Chlamydomonas reinhardtii to Homo sapiens. Many neuronal and endocrine functions are dependent upon amidated peptides; additional amidated peptides are growth promoters in tumours. The amidation reaction occurs in two steps, glycine α‐hydroxylation followed by dealkylation to generate the α‐amide product. Currently, most potentially useful inhibitors target the first reaction, which is rate‐limiting. PAM is a membrane‐bound enzyme that visits the cell surface during peptide secretion. PAM is then used again in the biosynthetic pathway, meaning that cell‐impermeable inhibitors or inactivators could have therapeutic value for the treatment of cancer or psychiatric abnormalities. To date, inhibitor design has not fully exploited the structures and mechanistic details of PAM.
Effects of figural and numerical presentation formats on growing pattern performance

Prior work exploring preschool-aged children’s reasoning with repeating patterns has shown that patterning ability is an important predictor of math achievement; however, there is limited research exploring older children’s growing pattern task performance. The current study tested whether presentation format impacts performance on growing pattern problems, and whether the effects of presentation format extend to transfer word problems for which no patterns are provided. Sixth grade students were randomly assigned to complete several growing pattern tasks in one of three presentation formats (figures, sequences of values, or tables of values), and later completed transfer story problems with no figures, sequences, or tables provided. Findings suggest that presenting growing patterns as figures can benefit performance, although these benefits may depend on both pattern type and task. No differences were observed in performance on transfer problems, likely because students rarely spontaneously generated figures. Additional exploratory analyses suggest that performance on growing pattern problems may be related to both standardized math ability and fraction task performance, whereas inhibitory control may only be related to performance for specific patterning tasks. These findings have implications for educators because describing/expressing patterns is critical to algebra and higher-level mathematics.
Teacher identity and Religion Education in Life Orientation

Integral to the Life Orientation curriculum is democracy and human right. This article contends that considering human rights cannot simply be a theoretical exercise as the implementation thereof affects lived human experience. Currently held narratives of lived experience need to be dialogically explored. Integrally linked to any such exploration is the identity of the explorer. It can be said that individuals are made to varying degrees by systems and networks of power in society, including dominant discourses. However, they also have the capacity, by exercising individual agency, to make themselves according to the way in which they respond to the intersections that shape identity, including ethnicity, culture, class, religion, gender, sexual orientation and so forth. This article seeks to explore teacher identity and, in particular, teacher religious identity, with a view to transformed Religion Education. The argument is made for Life Orientation teachers to negotiate their religious identity from a position of ‘religious identity paralysis’ or ‘religious identity paradox’ or even ‘religious identity flexibility’ to one of ‘religious identity transformation’. Both in-service and pre-service teachers participated in the studies informing this article.
Fe2O3 Microcubes Derived from Metal–Organic Frameworks for Lithium-Ion Storage with Excellent Performance

Transition metal oxides are regarded as a potential electrode material for lithium-ion storage due to it features high theoretical capacity and low cost. In this study, the possibility of Fe2O3 microcubes as an electrode material for lithium-ion storage was investigated, where the anode electrode of Fe2O3 microcubes were created through Prussian blue (PB) metal–organic frameworks (MOFs) and followed by the calcination process at high temperature. The results showed that the Fe2O3 microcubes electrode obtained by the calcination process at 500 °C exhibited superior electrochemical performances than that of Fe2O3 obtained by the calcination process at 700 °C. The increase in calcination temperature will lead to the further sintering reaction between the particles and the formation of cracks and voids in crystals that eventually lead to the breakup of microcube and so lower stable structure of the Fe2O3 microcubes electrode. Fe2O3 microcubes exhibited an excellent/stable lithium storage performance and thus is a promising anode material for LIBs.
Land Use Transitions and Farm Performance in China: A Perspective of Land Fragmentation

Land fragmentation (LF) is widespread worldwide and affects farmers’ decision-making and, thus, farm performance. We used detailed household survey data at the crop level from ten provinces in China to construct four LF indicators and six farm performance indicators. We ran a set of regression models using OLS methods to analyse the relationship between LF and farm performance. The results showed that (1) LF increased the input of production material and labour costs; (2) LF reduced farmers’ purchasing of mechanical services and the efficiency of ploughing; and (3) LF may increase technical efficiency (this result, however, was not sufficiently robust and had no effect on yield). Generally speaking, LF was negatively related to farm performance. To improve farm performance, it is recommended that decision-makers speed up land transfer and land consolidation, stabilise land property rights, establish land-transfer intermediary organisations and promote large-scale production.
Temperature-Dependent Creep Behavior and Quasi-Static Mechanical Properties of Heat-Treated Wood

In this paper, Berkovich depth-sensing indentation has been used to study the effects of the temperature-dependent quasi-static mechanical properties and creep deformation of heat-treated wood at temperatures from 20 °C to 180 °C. The characteristics of the load–depth curve, creep strain rate, creep compliance, and creep stress exponent of heat-treated wood are evaluated. The results showed that high temperature heat treatment improved the hardness of wood cell walls and reduced the creep rate of wood cell walls. This is mainly due to the improvement of the crystallinity of the cellulose, and the recondensation and crosslinking reaction of the lignocellulose structure. The Burgers model is well fitted to study the creep behavior of heat-treated wood cell walls under different temperatures.
Optimizing clinical dosing of combination broadly neutralizing antibodies for HIV prevention

Broadly neutralizing antibodies (bNAbs) are promising agents to prevent HIV infection and achieve HIV remission without antiretroviral therapy (ART). As with ART, bNAb combinations are likely needed to cover HIV’s extensive diversity. Not all bNAbs are identical in terms of their breadth, potency, and in vivo longevity (half-life). Given these differences, it is important to optimally select the composition, or dose ratio, of combination bNAb therapies for future clinical studies. We developed a model that synthesizes 1) pharmacokinetics, 2) potency against a wide HIV diversity, 3) interaction models for how drugs work together, and 4) correlates that translate in vitro potency to clinical protection. We found optimization requires drug-specific balances between potency, longevity, and interaction type. As an example, tradeoffs between longevity and potency are shown by comparing a combination therapy to a bi-specific antibody (a single protein merging both bNAbs) that takes the better potency but the worse longevity of the two components. Then, we illustrate a realistic dose ratio optimization of a triple combination of VRC07, 3BNC117, and 10–1074 bNAbs. We apply protection estimates derived from both a non-human primate (NHP) challenge study meta-analysis and the human antibody mediated prevention (AMP) trials. In both cases, we find a 2:1:1 dose emphasizing VRC07 is nearly optimal. Our approach can be immediately applied to optimize the next generation of combination antibody prevention and cure studies.
Population mobility, urban centrality and subnetworks in China revealed by social sensing big data

Studying the spatial pattern of population flows is important to gain insights into economic connections, city networks and traffic demand. The dearth of integrative data suggests that the spatial pattern of population migration has still received relatively scant research with modified algorithms despite its vital guidance in epidemic control. To address this gap, we employ unique social sensing data from the Tencent migration platform to investigate the spatial configuration of population migration in China. Based on the identified 2,555,596 aggregated origin-destination records in 2018, we map the spatial pattern of population flow with the algorithm of eigenvector centrality. The geovisualisation illustrates that population flows present an uneven spatial pattern with a clear east/west divide. The geovisualisation depicts that the cities with higher administrative levels show corresponding high centrality to a certain extent. The results also show that subnetworks of migration flow demonstrate that population flows are near movements.
Kinetic study of the microwave‐induced thermal degradation of cv. Arbequina olive oils flavored with lemon verbena essential oil

The effect of typical domestic microwave heating (0 – 15 min, at 800 W) on the thermal degradation of unflavored and flavored olive oils ’ minor bioactive compounds and related antioxidant activity was studied. Olive oils from cv. Arbequina were flavored with lemon verbena essential oil (0%, 0.2% and 0.4%, w/w) leading to a linear increase of total phenols (112 – 160 mg gallic acid kg (cid:1) 1 oil, R