Miracle-dz/UniFAR-FTUs huggingface dataset:
PENDIDIKAN KELUARGA, SAVING ATTITUDES DAN PERENCANAAN PENSIUN: STUDI PADA BADAN PENYELANGGARAN JAMINAN SOSIAL KESEHATAN DI KOTA TONDANO [FAMILY EDUCATION, SAVING ATTITUDES AND RETIREMENT PLANNING: STUDY OF BADAN PENYELANGGARAN JAMINAN SOSIAL KESEHATAN IN TONDANO CITY]

This study aims to determine the effect of family education on retirement planning at the Tondano Branch Health BPSJS office, the effect of saving attitudes on retirement planning at the Tondano Health BPSJS office, and the influence of family education and saving attitudes towards retirement planning at the BPSJS office. Tondano Health Branch. This study is a causal associative study with a population of 35 members. The number of samples of 35 people was taken using a saturated sampling technique. Methods of data collection using questionnaires and documentation. The data analysis technique used multiple regression. The results of this study indicate that there is a positive and significant effect of family education on retirement planning at the Tondano Branch Health BPSJS office, that there is a positive and significant influence on saving attitudes towards retirement planning at the Tondano Branch Health BPSJS office, and that there is a positive and significant effect, and significant influence of family education and saving attitudes towards retirement planning at the health BPSJS office Tondano Branch. The effective contribution of family education variables and saving attitudes is 82.1% towards retirement planning.BAHASA INDONESIA ABSTRACTPenelitian ini bertujuan untuk mengetahui pengaruh pendidikan keluarga terhadap perencanaan pensiun di kantor BPSJS Kesehatan Cabang Tondano, pengaruh sikap menabung terhadap perencanaan pensiun di kantor BPSJS Kesehatan Tondano, dan pengaruh pendidikan keluarga dan sikap menabung terhadap perencanaan pensiun pada kantor BPJS Cabang Kesehatan Tondano. Penelitian ini merupakan penelitian asosiatif kausal dengan jumlah populasi 35 orang. Jumlah sampel 35 orang diambil dengan menggunakan teknik sampling jenuh. Metode pengumpulan data menggunakan angket dan dokumentasi. Teknik analisis data menggunakan regresi berganda. Hasil penelitian ini menunjukkan ada pengaruh positif dan signifikan pendidikan keluarga terhadap perencanaan pensiun di kantor BPSJS Kesehatan Cabang Tondano, ada pengaruh positif dan signifikan sikap menabung terhadap perencanaan pensiun di kantor BPSJS Kesehatan Cabang Tondano, dan ada merupakan pengaruh yang positif dan signifikan, dan ada pengaruh signifikan pendidikan keluarga dan sikap menabung terhadap perencanaan pensiun di BPSJS kesehatan Cabang Tondano. Kontribusi efektif variabel pendidikan keluarga dan sikap menabung sebesar 82,1% terhadap perencanaan pensiun.
Superior thermoelectric performance via "anti-reflection" enabled double-barrier structures

We demonstrate theoretically using the atomistic non-equilibrium Green's function formalism with the inclusion of self-consistent charging, the design of a superior thermoelectric generator based on an "anti-reflection" coated double barrier resonant tunnelling diode. Unlike a typical double barrier device, we show that enabling the anti-reflection design facilitates a "boxcar" type feature in its transmission spectrum, which significantly enhances the thermoelectric performance. It is demonstrated that the best operating regime of this device offers a maximum power in the range of $0.7$ to $0.9 MW/m^{2}$ at efficiencies ranging from $46$ to $54\%$ of Carnot efficiency. The physics of charge and heat transport in the ballistic regime of operation helps us gain additional insights on how a large number of transverse current carrying modes boost the output power and simultaneously how the diminishing effects of high-energy parasitic currents aid the efficiency. Finally, a comparative study with a conventional double barrier thermoelectric is presented in terms of standard performance parameters which clearly reveals the performance benefits of enabling an anti-reflection coating.
Portable tracker for neurophysiological research of sport shooting

In this work we present the development process of a wireless portable module. It is developed to record various characteristics during sport shooting, such as automatic detection of the moment of shot and barrel movement during aiming, taking into account the peculiarities of its use in neurophysiological research. We propose an approach allowing to synchronize devices in a wireless local network with high accuracy (synchronization accuracy was 2 ms), as well as a method of logging the recorded data at a sampling rate of up to 2 kHz on an onboard flash drive.
Enzymatic Hydrolysis of Pulse Proteins as a Tool to Improve Techno-Functional Properties

Pulse proteins are being increasingly investigated as nutritious and functional ingredients which could provide alternatives to animal proteins; however, pulse protein ingredients do not always meet the functionality requirements necessary for various applications. Consequently, enzymatic hydrolysis can be employed as a means of improving functional properties such as solubility, emulsifying, foaming, and gelling properties. This review aims to examine the current literature regarding modification of these properties with enzymatic hydrolysis. The effects of enzymatic hydrolysis on the functionality of pulse proteins generally varies considerably based on the enzyme, substrate, processing steps such as heat treatment, degree of hydrolysis, and pH. Differences in protease specificity as well as protein structure allow for a wide variety of peptide mixtures to be generated, with varying hydrophobic and electrostatic properties. Typically, the most significant improvements are seen when the original protein ingredient has poor initial functionality. Solubility is usually improved in the mildly acidic range, which may also correspond with improved foaming and emulsifying properties. More work should be carried out on the potential of enzymatic hydrolysis to modify gelation properties of pulse proteins, as the literature is currently lacking. Overall, careful selection of proteases and control of hydrolysis will be necessary to maximize the potential of enzymatic hydrolysis as a tool to improve pulse protein functionality and broaden the range of potential applications.
IN SILICO EVALUATION OF DRUGS TOXICOLOGICAL PROPERTIES IN THE PRACTICAL COURSE OF MEDICINAL CHEMISTRY

The computational tools are important to help the understanding of concepts in the medicinal chemistry discipline. This work shows a guide of practical lesson within this discipline using four drugs with different market time and a free program of toxicological evaluation of mutagenic and tumorigenic risks, irritant and reproductive effects of chemical compounds. The objective was to introduce students to the current in silico methodology, to discuss toxicological concepts based on the results and to analyze the importance of toxicological studies in the pharmaceutical area. The fundamentals of the discipline were contextualized and the new approach proved to be an important tool in the teaching-learning process.
In Silico Prediction of Skin Permeability Using a Two-QSAR Approach

Topical and transdermal drug delivery is an effective, safe, and preferred route of drug administration. As such, skin permeability is one of the critical parameters that should be taken into consideration in the process of drug discovery and development. The ex vivo human skin model is considered as the best surrogate to evaluate in vivo skin permeability. This investigation adopted a novel two-QSAR scheme by collectively incorporating machine learning-based hierarchical support vector regression (HSVR) and classical partial least square (PLS) to predict the skin permeability coefficient and to uncover the intrinsic permeation mechanism, respectively, based on ex vivo excised human skin permeability data compiled from the literature. The derived HSVR model functioned better than PLS as represented by the predictive performance in the training set, test set, and outlier set in addition to various statistical estimations. HSVR also delivered consistent performance upon the application of a mock test, which purposely mimicked the real challenges. PLS, contrarily, uncovered the interpretable relevance between selected descriptors and skin permeability. Thus, the synergy between interpretable PLS and predictive HSVR models can be of great use for facilitating drug discovery and development by predicting skin permeability.
Increased Fatigability in Women With Persistent Cancer-Related Fatigue After Breast Cancer Treatment: A Pilot Study

Purpose: To examine whether survivors of breast cancer (SBC) with persistent cancer-related fatigue (CRF) have greater fatigability than their nonfatigued counterparts. Methods: Measures of fatigability, including endurance, perceived exertion, lower extremity muscle force and power, and sit-to-stand time (STST), were assessed in 43 women (21 with persistent CRF) after a sit-to-stand fatigue (STSF) task. Group differences in fatigability outcomes were examined using analysis of variance. Results: SBC with persistent CRF had lower endurance (P = .003, ηp2 = 0.205) and reported greater perceived exertion (P < .001, ηp2 = 0.284) during the STSF task, and demonstrated lower postexertional force (P = .035, ηp2 = 0.109), power (P = .001, ηp2 = 0.242), and slower STST (P = .001, ηp2 = 0.258) compared with SBC without CRF. Conclusions: SBC with persistent CRF have increased fatigability compared with those without CRF. Our findings suggest that exercise recommendations for women with persistent CRF after breast cancer treatment should include activities that increase lower limb muscle force and power, such as heavy resistance or explosive-type strength training.
Döviz Kuru Riski Yönetimine Sektörel Bir Yaklaşım

Finansal piyasalarin derinlesmesi ve genislemesinin yaninda kuresellesme ile birlikte doviz kuru hareketleri sadece finansal kuruluslar degil ayni zamanda reel sektor firmalari icin daha onemli hale gelmistir. Doviz kuru riski, finansal olmayan firmalarda hem varliklar hem de kaynaklar acisindan onemlidir. Maruz kalinan doviz kuru riskinin yonetilmesi bu firmalarin rekabet gucu uzerinde etkili olacaktir. Bu calismada, yogunlasmanin cok yuksek oldugu tutun endustrisinde yer alan firmalarin doviz kurlarindaki degisimlerden etkilenme duzeyleri ve kur riski yonetimine yonelik yaklasimlarinin belirlenmesi arastirilmistir. Firmalarin ozellikle ihracat islemlerinde doviz kuru riskinden korunmayi istedikleri sonucuna varilmistir. Firmalarin onemli bir kisminda sistematik sekilde kur riski yonetiminin olmadigi belirlenmistir. Firmalar kur riskinden korunmak amaciyla isletme ici teknikleri finansal araclara gore daha fazla tercih etmektedirler. Finansal araclarin kur riskinden korunmak amaciyla kullanilmamasinda, ithalat islemlerinin bulunmasi ve kur artisina yonelik beklentiler etkili olmustur. Gelecek 3 aylik donem icin doviz kurlarinda %10’luk artis ve azalisa gore sunulan iki farkli senaryoya gore, firmalarin doviz kuru riskinin yonetilmesinde cogunlukla isletme ici yontemleri tercih ettikleri sonucuna ulasilmistir
Factors Affect the Eradication Rate of Helicobacter pylori by Modified Quadruple Therapy: A Prospective Cohort Study

Objective This study aimed to investigate related factors affecting the eradication rate of Helicobacter pylori (Hp) by modified quadruple therapy. Methods Between September 2020 and March 2021, 341 patients who were diagnosed with Hp infection and whose infections were confirmed by gastroscopy, a histological examination, and a C13-UBT without culturing and antimicrobial susceptibility studies received a two-week anti-Hp treatment, a modified quadruple therapy, in our department. The result of C13-UBT was rechecked 4 weeks after the drug withdrawal, and the patients were divided into two groups—a success group and a failure group—according to the final breath result. The general clinical information and related laboratory indexes of each patient were collected, and the factors affecting the eradication rate were analyzed. Results The total clinical eradication rate was 80.06% (273/341), and the failure rate was 19.94% (68/341), correspondingly. Univariate analysis identified statistically significant differences between the two groups in serum 25-hydroxyvitamin D levels, presence of oral diseases, positive cytotoxin-associated gene A (CagA), and medical compliance (P < 0.05). Meanwhile, the use of a proton pump inhibitor (PPIs) and antibiotics was statistically different (P < 0.05). Logistic regression analysis revealed that vitamin D level (<20 ng/mL) [OR = 98.56, 95% CI (29.01–334.83), P < 0.001] and medical compliance [OR = 148.18, 95% CI (37.64–583.33), P < 0.001] were independent effecting factors for eradication rate. Conclusion Serum 25-hydroxyvitamin D level lower than 20 ng/mL may affect the success of eradication of Hp and is an independent risk factor for eradication failure.
Detection of DDoS Attacks in SDN

Software Defined Networking (SDN) is a network management approach that allows network configuration to be dynamically and automatically changed based on program logic in order to improve performance. The control plane and data plane make up an SDN. DDoS attacks can lead to financial losses or worse if they disrupt network services. This paper presents a method for detecting and mitigating attacks with less resource consumption by utilizing SDN's central control.
A Change Detection Method Based on Full-scale Skip Connections and Mixed Pooling Module

Change detection is one of the main driving forces for the continuous development of remote sensing image processing technology. As a pixel-level detection task, change detection attaches great importance to the utilization of original spatial information as well as contextual information. In this paper, we propose a deep learning-based change detection method that combines full-scale skip connections and mixed pooling module (MPM). Firstly, full-scale skip connections make full use of the spatial information of features at different scales to improve change detection performance. In addition, we introduce MPM in this method due to the complexity of scene information in images, which can enhance the understanding of the scene with rich contextual information and boost the detection ability of strip shape targets. Finally, our experimental results on two public datasets demonstrate that the proposed method has good performance.
Duration of hypertension and prevalence of end-organ damage in hypertensive patients

The objective of this study is to determine the prevalence of end-organ damage in hypertensive patients in a tertiary care hospital in Azad Kashmir. The study was conducted in a public sector teaching hospital of AJK-Medical College between March 2019 and Feb 2020. Adult hypertensive patients above the age of 27 years were included in the study from out-patient and in-patient departments. A standard Performa was used to collect and document the demographic information, medical history and physical examination of patients. The age, sex, residential area, marital status, education, profession, presenting complaints, smoking, addictions, functional status, and physical activity were recorded. The measurement of Blood Pressure (BP) was performed with a mercury sphygmomanometer and end-organs damage (Retinopathy, Nephropathy, Cardiovascular and cerebrovascular disease) was assessed by clinical evaluation and relevant investigations. A total of 100, hypertensive patients were enrolled in the study between the ages of 27 to 96 years. The mean age of the participants was 57 years (Std. deviation 17.8). 55% of patients were male while 45% of patients were female. 23% had good control of hypertension while 77% had poor control. 7% of participants were monitoring their BP on daily basis, 32% weekly, 39% once a month while 22% never had any schedule of monitoring their Blood Pressure. A family history of hypertension was present in 61%. Overall, 91% of the participants had retinopathy, 48% had nephropathy, 48% had cardiovascular disease and 19% had evidence of stroke. In conclusion, there is a high prevalence of End-Organ damage in middle age and elderly hypertensive patients. Keywords: Hypertension, hypertensive end-organ damage.
Molecular detection of endosymbionts in local populations of Helicoverpa armigera (Lepidoptera: Noctuidae) in European part of Russia

Cotton bollworm Helicoverpa armigera is one of the most polyphagous and cosmopolitan pests. Intracellular endosymbionts are widespread in Lepidoptera, often playing an important role in their dynamics. The prevalence of endosymbionts of cotton bollworm in Russia was not investigated. Cotton bollworm larvae and adults were collected in 2018–2020 in Krasnodar Area, and in Voronezh and Saratov Regions (from 131 to 170 insects) and analyzed by PCR using sets of group-specific primers for baculoviruses (locus lef8), bacteria of the genus of Wolbachia (locus wsp), and microsporidia (locus SSU rRNA). Level of infection with baculoviruses was 16 % for the sample of 32 individuals collected in Temryuk District of Krasnodar Area in 2018. The infection rate of the entire sample of 170 individuals was 2.9 %. The lef8 locus demonstrated 98.7–99.6 % of sequence similarity to the nuclear polyhedrosis virus isolates from the cotton bollworm and American bollworm. Among the tested 131 insects, bacteria of the genus of Wolbachia were not detected. PCR screening for microsporidia revealed one positive larvae among 19 insects collected in Krasnoarmeysk District of Krasnodar Area in 2019, which corresponded to the prevalence of 5 %. Partial sequencing of the genes coding for SSU rRNA and largest subunit RNA polymerase II made it possible to identify the new isolate as N. bombycis.
agReg-SNPdb-Plants: A Database of Regulatory SNPs for Agricultural Plant Species

Simple Summary In breeding research, the investigation of regulatory SNPs (rSNPs) is becoming increasingly important due to their potential causal role for specific functional traits. Especially for crop species, there is still a lack of systematic analyses to detect rSNPs and their predicted effects on the binding of transcription factors. In this study, we present agReg-SNPdb-Plants, a database storing genome-wide collections of regulatory SNPs for agricultural plant species which can be queried via a web interface. Abstract Single nucleotide polymorphisms (SNPs) that are located in the promoter regions of genes and affect the binding of transcription factors (TFs) are called regulatory SNPs (rSNPs). Their identification can be highly valuable for the interpretation of genome-wide association studies (GWAS), since rSNPs can reveal the biologically causative variant and decipher the regulatory mechanisms behind a phenotype. In our previous work, we presented agReg-SNPdb, a database of regulatory SNPs for agriculturally important animal species. To complement this previous work, in this study we present the extension agReg-SNPdb-Plants storing rSNPs and their predicted effects on TF-binding for 13 agriculturally important plant species and subspecies (Brassica napus, Helianthus annuus, Hordeum vulgare, Oryza glaberrima, Oryza glumipatula, Oryza sativa Indica, Oryza sativa Japonica, Solanum lycopersicum, Sorghum bicolor, Triticum aestivum, Triticum turgidum, Vitis vinifera, and Zea mays). agReg-SNPdb-Plants can be queried via a web interface that allows users to search for SNP IDs, chromosomal regions, or genes. For a comprehensive interpretation of GWAS results or larger SNP-sets, it is possible to download the whole list of SNPs and their impact on transcription factor binding sites (TFBSs) from the website chromosome-wise.
Assessment of Spatial Distribution and Temporal Variations of the Phreatic Groundwater Level using Geostatistical Modelling: The Case of Oued Souf Valley—Southern East of Algeria

Since the beginning of the 1980s, several regions in the northern Sahara of Algeria have been confronting the rising groundwater. Among all these regions, Oued Souf Valley represented one of the most acute affected by this phenomenon. Due to the natural topography and the insufficient/weakness of water management and miscoordination between different sectors that are represented by intensive exploitation of deep groundwater reservoirs which returns to the shallow aquifer, absence of sewage and drainage network, leakage from drinking water supply system, the groundwater has raised to the surface or near to the surface, affecting the traditional cultural environment and urban areas and degrading all socio-economic aspects of the Oued Souf habitants. To preserve the Oued Souf environment, a vertical drainage system has been constructed. Consequently, in this research, an evaluation of the vertical drainage system performance and its impact on groundwater level stabilization has been performed by mapping the water table of the phreatic groundwater level using geostatistical modeling using ordinary kriging (OK) interpolation method, which has been applied to analyze the spatial and temporal structure of groundwater level fluctuation. Meanwhile, hierarchical cluster analysis (HCA) was applied for grouping the wells based on the groundwater fluctuations for 2008, 2009, 2014, 2016, 2018, and 2021. However, the vertical drainage system reflected a significant decline of groundwater from 2009 to 2018 due to the important drained volumes through it but another rising phenomenon might be threatening the region in the near future and this is what was indicated in the 2021 groundwater level data. Cluster analysis has generated four groups based on their fluctuation means that are increasing from the first group to the fourth group ascendingly. The first cluster grouped the drains that have a shallow depth (average mean of 5.91 mbgl) and declined over the clusters. The clusters are spatially combined with significant separation of the fourth cluster which represents the deepest group (12.89 mbgl). Based on this research, several factors are influencing the stability of the phreatic groundwater level and even the performance of the drainage system, the most important of which is the overexploitation from deep groundwater reservoirs such as complex terminal and continental intercalary (in drinking and irrigation) and even the illegal use of the phreatic groundwater with important quantities for irrigation and illegal industries.
The Family Care’s Telenursing for Elderly with COVID-19

The COVID-19 pandemic has had an impact on health systems in many countries, including Indonesia. From this crisis, nurses as one of the front lines in COVID-19 health services have an important role in providing nursing services for self-isolated patients at home through family care's telenursing services. Teh Method of this study uses a case report design in 1 case of a family with an elderly confirmed positive for covid 19 that carried out through virtual monitoring with a telenursing approach. Observation and analysis of the case report of family care's telenursing based on the 5 Family Health Task (FHT) approach according to Maglaya's theory associated with NANDA-NOC-NIC International. The Results study shows that the family care's telenursing helps the elderly and families recognize the covid 19 problems, making decisions for appropriate treatment, caring for the elderly through telenursing, modifying a healthy environment for the elderly, and utilizing telenursing so that this program can effectively help families and the elderly achieve maximum health status during the self-quarantine period in Home. This study is expected to be a reference for related institutions to develop family care's telenursing in providing family nursing care for families with COVID-19 problems