Miracle-dz/UniFAR-FTUs huggingface dataset:
Research on Product Innovation of Tourism Enterprises under the Background of Aging

How to adapt to the development status of an aging population, develop innovative tourism products and improve the tourism experience of elderly tourists have become an important issue for tourism enterprises to be solved. Based on this, this paper constructs a structural equation model to explore the impact of tourist-to-tourist interactions on subjective well-being. Using SPSS and AMOS software to analyze the data of 416 elderly tourists in Chengdu, China, it is found that the interaction between elderly tourists directly or indirectly affects subjective well-being. Well-being and the value of tourism experience have a partial mediating effect on it. The tourism companies can innovate tourism service products in terms of improving employee service skills, creating a good tourism atmosphere, and guiding the interactive behavior of elderly tourists.
Perceived Advantages of and Concerns About Mobile Food Pantries Among Mothers Who Utilized Food Pantries Before or During the COVID-19 Pandemic

ABSTRACT The COVID-19 pandemic drastically increased the demand for food pantries. Using data from an online survey in early spring 2021, we explored interest in mobile food pantries among US mothers who received food from a food pantry before or during the COVID-19 pandemic (n = 53). Sixty percent were very interested in getting food from a mobile food pantry, 19% were quite a bit interested, and 21% were somewhat interested. Participants liked the convenience and reduced risk of COVID-19 infection but had cleanliness and accessibility concerns. Mobile food pantries may be one approach to address food access among households with children.
Efficacy evaluation of novel organic iron complexes in laying hens: effects on laying performance, egg quality, egg iron content, and blood biochemical parameters

Objective This study was conducted to determine the optimal dose of novel iron amino acid complexes (Fe-Lys-Glu) by measuring laying performance, egg quality, egg iron (Fe) concentrations, and blood biochemical parameters in laying hens. Methods A total of 1,260 18-week-old healthy Beijing White laying hens were randomly divided into 7 groups with 12 replicates of 15 birds each. After a 2-wk acclimation to the basal diet, hens were fed diets supplemented with 0 (negative control, the analyzed innate iron content was 75.06 mg/kg), 15, 30, 45, 60, and 75 mg Fe/kg as Fe-Lys-Glu or 45 mg Fe/kg from FeSO4 (positive control) for 24 wk. Results Results showed that compared with the negative and positive control groups, dietary supplementation with 30 to 75 mg Fe/kg from Fe-Lys-Glu significantly (linear and quadratic, p<0.05) increased the laying rate (LR) and average daily egg weight (ADEW); hens administered 45 to 75 mg Fe/kg as Fe-Lys-Glu showed a remarkable (linear, p<0.05) decrease in feed conversion ratio. There were no significant differences among all groups in egg quality. The iron concentrations in egg yolk and serum were elevated by increasing Fe-Lys-Glu levels, and the highest iron content was found in 75 mg Fe/kg group. In addition, hens fed 45 mg Fe/kg from Fe-Lys-Glu had (linear and quadratic, p<0.05) higher yolk Fe contents than that with the same dosage of FeSO4 supplementation. The red blood cell (RBC) count and hemoglobin content (linear and quadratic, p<0.05) increased obviously in the groups fed with 30 to 75 mg Fe/kg as Fe-Lys-Glu in comparison with the control group. Fe-Lys-Glu supplementation also (linear and quadratic, p<0.05) enhanced the activity of copper/zinc-superoxide dismutase (Cu/Zn-SOD) in serum, as a result, the serum malonaldehyde content (linear and quadratic, p<0.05) decreased in hens received 60 to 75 mg Fe/kg as Fe-Lys-Glu. Conclusion Supplementation Fe-Lys-Glu in laying hens could substitute for FeSO4 and the optimal additive levels of Fe-Lys-Glu are 45 mg Fe/kg in layers diets based on the quadratic regression analysis of LR, ADEW, RBC, and Cu/Zn-SOD.
Golgi Dysfunctions in Ciliopathies

The Golgi apparatus (GA) is essential for intracellular sorting, trafficking and the targeting of proteins to specific cellular compartments. Anatomically, the GA spreads all over the cell but is also particularly enriched close to the base of the primary cilium. This peculiar organelle protrudes at the surface of almost all cells and fulfills many cellular functions, in particular during development, when a dysfunction of the primary cilium can lead to disorders called ciliopathies. While ciliopathies caused by loss of ciliated proteins have been extensively documented, several studies suggest that alterations of GA and GA-associated proteins can also affect ciliogenesis. Here, we aim to discuss how the loss-of-function of genes coding these proteins induces ciliary defects and results in ciliopathies.
Input-to-State Stability of Time-Delay Systems With Hybrid Impulses and Continuous Subdynamics Based on Vector Lyapunov Function

This article focuses on input-to-state stability (ISS) of impulsive time-delay systems where the hybrid effect of impulses with time-dependent multiple jump maps in different subsystems is fully considered. By virtue of M-matrix and vector Lyapunov function, some theorems for ISS are established for Krasovskii-type conditions which avoid the common threshold of impulses in subsystems and allow the simultaneous existence of stable and unstable continuous subdynamics. If the time intervals between impulses are bounded, the ISS of time-delay systems can be ensured even though hybrid impulses exist in each subsystem, which determines the robustness of stable time-delay systems with respect to hybrid impulses. The unstable time-delay systems with different subdynamics can be stabilized in input-to-state-stability sense by involving hybrid impulses. In addition, several extended criteria are presented to bridge the results derived via vector Lyapunov function, scalar Lyapunov function, and comparison principle. At last, the theoretical results are validated by numerical example and a simplified model of sewage treatment tank.
Digital false information at scale in the European Union: Current state of research in various disciplines, and future directions

Digital false information is a global problem and the European Union (EU) has taken profound actions to counter it. However, from an academic perspective the United States has attracted particular attention. This article aims at mapping the current state of academic inquiry into false information at scale in the EU across fields. Systematic filtering of academic contributions resulted in the identification of 93 papers. We found that Italy is the most frequently studied country, and the country of affiliation for most contributing authors. The fields that are best represented are computer science and information studies, followed by social science, communication, and media studies. Based on the review, we call for (1) a greater focus on cross-platform studies; (2) resampling of similar events, such as elections, to detect reoccurring patterns; and (3) longitudinal studies across events to detect similarities, for instance, in who spreads misinformation.
Variables applied in a NMR image decomposition with the aid of GCCA

The paper describes the influence of variable selection on an image decomposition. A NMR image is a source of a set of variables describing pixels of the image: gray level, gradient magnitude and seven variables derived from gradient magnitudes of neighbouring pixels. A selection of the variables is the essence of the matter at this stage of the image processing. Two suggestions are proposed and tested: a normalization of gradient magnitude of the pixel by dividing it by a value of the gray level, and development of a nonlinear sequence of thresholds which are used in comparison of adjacent pixels.
The Influence of Legal Mandates on Public Participation

Legal mandates are a common mechanism to stimulate government agencies to engage the public. Research shows managerial efforts can also affect civic engagement. We first examine whether local government departments that are legally mandated to engage the public have more public participation than departments that are not mandated to do so. We then explore the relationship between manager perceptions of public participation and the frequency of public participation. Finally, we analyze the interactive effect of legal mandates and managerial perceptions. To investigate our research questions, we use regression models on data from a 2018 nationally representative survey of 527 local government managers in the United States. The results indicate legal mandates are not significantly related to public participation, but managerial perceptions are a key factor. These findings support pursuing a managerial approach to advance public participation in local government.
Strong carrier-scattering in iron-pnictide superconductors L n FeAsO 1 − y ( L n = La and Nd) obtained from charge transport experiments

Characteristic normal-state charge transport is found in the oxygen-deficient iron-arsenides $Ln{\text{FeAsO}}_{1\ensuremath{-}y}$ ($Ln$: La and Nd) with the highest ${T}_{c}$'s among known Fe-based superconductors. The effect of ``doping'' in this system is mainly on the carrier scattering, quite distinct from that in high-${T}_{c}$ cuprates. In the superconducting regime of the La system with maximum ${T}_{c}=28\text{ }\text{K}$, the low-temperature resistivity is dominated by a ${T}^{2}$ term. On the other hand, in the Nd system with ${T}_{c}$ higher than 40 K, the carriers are subject to stronger scattering showing $T$-linear resistivity and small magnetoresistance. Such strong scattering appears crucial for high-${T}_{c}$ superconductivity in the iron-based system.
Progress of Muscle Chain Theory in Shoulder Pain Rehabilitation: Potential Ideas for Pulmonary Rehabilitation

Pulmonary dysfunction is very common in stroke patients. A study has shown that acute stroke patients often cause a series of pulmonary dysfunction due to primary damage to the respiratory center, which is an important reason for hindering disease treatment and recovery. American Thoracic Society (ATS) and the European Respiratory Society (ERS) pointed out that pulmonary rehabilitation (PR) can be applied to the rehabilitation of stroke patients to improve their lung function. PR can improve the respiratory muscle strength of stroke patients, which is beneficial to improving the respiratory function of patients. At the same time, it can also significantly increase the maximum oxygen intake of patients, effectively improve the cardiopulmonary function of stroke patients, and reduce respiratory complications such as aspiration pneumonia. However, the common dysfunction of joints and muscles such as shoulder pain after stroke will affect the process of pulmonary rehabilitation. This is mainly because the changes in the position of the shoulder girdle, the decrease in the range of motion of the cervical and thoracic spine, and the changes in the cervical spondylolisthesis position caused by the elevation of the upper limbs will directly affect the breathing movement during the pulmonary rehabilitation process. The instability of the spine will weaken the deep abdominal muscles and reduce the function of the diaphragm; moreover, changes in the alignment and stability of the cervical and thoracic spine will also lead to wrong breathing methods. Therefore, it is of practical clinical significance to evaluate the functional rehabilitation of shoulder joint muscles and evaluate the efficacy of stroke patients to improve their respiratory function. This article through an extensive review of domestic and foreign literature in recent years, combined with clinical practice experience, summarizes the practical application of chain structure theory in the fields of rehabilitation training, postural adjustment, pain relief, etc., and further studies the functional exercise method based on muscle chain theory. The research on the muscle chain of shoulder pain rehabilitation as a model illustrates the positive effect of reconstructing neuroarticular muscle function on the respiratory system, hoping to provide new ideas for the treatment of respiratory diseases in stroke patients.
On the cuspidalization problem for hyperbolic curves over finite fields

In this paper, we study some group-theoretic constructions associated to arithmetic fundamental groups of hyperbolic curves over finite fields. One of the main results of this paper asserts that any Frobenius-preserving isomorphism between the geometrically pro-$l$ fundamental groups of hyperbolic curves with one given point removed induces an isomorphism between the geometrically pro-$l$ fundamental groups of the hyperbolic curves obtained by removing other points. Finally, we apply this result to obtain results concerning certain cuspidalization problems for fundamental groups of (not necessarily proper) hyperbolic curves over finite fields.
Automatic extraction of relevant nodes in biochemical networks

In this paper we describe a novel method for extracting a set of nodes that best capture the connections between k given nodes of interest in a biochemical network. This method relies on the projection of the nodes of the network, seen as an undirected graph, into an euclidean space. Euclidean distances between nodes in the projected space correspond to their commute time distances in the original graph, a measure based on a random walk model on the graph. Commute time reflects the distance between two nodes while considering all paths connecting them. Results on artificial data illustrate the interest of this approach.
Genetic Variability Studies on Drought Tolerance using Agro-Morphological and Yield Contributing Traits in Rapeseed-Mustard

A study was conducted during rabi season (October-May), 2018−2019 at the Experimental Farm of Department of Genetics and Plant Breeding, CSK HPKV, Palampur (HP), India to develop reliable selection criteria for drought tolerance. 25 advanced breeding lines of different Brassica species were used to determine their mean performance, components of variability, heritability and genetic advance under moisture stress conditions created at rosette stage, flower initiation stage and siliqua formation stage using various agro-morphological and yield contributing traits. Sufficient genetic variability was found for almost all the characters except for 1000-seed weight under non-stress stage conditions. Estimates of parameters of variability revealed that phenotypic coefficients of variation were higher than their respective genotypic coefficients of variation. Under moisture stress conditions, high heritability coupled with high genetic advance was observed for number of secondary branches plant-1 in non-stress and all the moisture-stress stages. Siliqua formation stage was found most susceptible to moisture stress conditions which also led to maximum reduction in seed yield. Using drought susceptibility index, the genotypes HPBS-1 followed by HPKM-04-1 were found to be moderately drought tolerant as these exhibited the lowest drought susceptibility index value in Stage-I and Stage-III while in Stage-II, RCC-4×Varuna followed by HPBS-1 exhibited lowest drought susceptibility index value. Therefore, systematic characterization of differences in physiological responses to drought stress among elite lines is helpful in understanding mechanisms of drought resistance. Hence, traits like primary branches plant-1, secondary branches plant-1, siliquae plant-1, seeds siliqua-1, seed yield plant-1 and 1000-seed weight can be further used in selection criteria for future breeding programme aimed for enhancing drought tolerance.
Spectral Type of One-Parameter Group of Unitary Operators with Transversal Group

It is an important problem to determine the spectral type of automorphisms or flows on a probability measure space. We shall deal with a unitary operator U and a 1-parameter group of unitary operators {Ut } on a separable Hilbert space H, and discuss their spectral types, although U and {Ut } are not necessarily supposed to be derived from an automorphism or a flow respectively.
Understanding the Relationship Between Age-Related Hearing Loss and Alzheimer’s Disease: A Narrative Review

Evidence suggests that hearing loss (HL), even at mild levels, increases the long-term risk of cognitive decline and incident dementia. Hearing loss is one of the modifiable risk factors for dementia, with approximately 4 million of the 50 million cases of dementia worldwide possibly attributed to untreated HL. This paper describes four possible mechanisms that have been suggested for the relationship between age-related hearing loss (ARHL) and Alzheimer’s disease (AD), which is the most common form of dementia. The first mechanism suggests mitochondrial dysfunction and altered signal pathways due to aging as a possible link between ARHL and AD. The second mechanism proposes that sensory degradation in hearing impaired people could explain the relationship between ARHL and AD. The occupation of cognitive resource (third) mechanism indicates that the association between ARHL and AD is a result of increased cognitive processing that is required to compensate for the degraded sensory input. The fourth mechanism is an expansion of the third mechanism, i.e., the function and structure interaction involves both cognitive resource occupation (neural activity) and AD pathology as the link between ARHL and AD. Exploring the specific mechanisms that provide the link between ARHL and AD has the potential to lead to innovative ideas for the diagnosis, prevention, and/or treatment of AD. This paper also provides insight into the current evidence for the use of hearing treatments as a possible treatment/prevention for AD, and if auditory assessments could provide an avenue for early detection of cognitive impairment associated with AD.
Predictors of Early Neurological Deterioration and Functional Outcome in Acute Ischemic Stroke: The Importance of Large Artery Disease, Hyperglycemia and Inflammatory Blood Biomarkers

Background Early neurological deterioration (END) in acute ischemic stroke (AIS) can be associated with poor outcome. The aim of this study was to investigate the association between infarction subtypes, biomarkers and END, and to identify patients with risk of unfavorable functional outcome. Materials and Methods This prospective study enrolled 101 patients with AIS. Neurological status was evaluated according to NIHSS at acute onset, on days 2, 3, and 90. END was defined as ≥2-point increase of NIHSS within 72 hours. Functional outcome was assessed using NIHSS and the modified Rankin Scale (mRS) at day 90. Results END was observed in 20, 8%. Patients with large artery disease had higher risk of developing END compared with patients with cardioembolism or small vessel disease (p <0.01). Significant higher blood glucose level and leukocytes were observed in the END group. Patients with END had higher scores of mRS at day 90 (p <0.01). Levels of NSE, IL-6, hsCRP and NT-proBNP were higher in the patients with unfavorable compared with favorable functional outcome. Conclusion Large artery disease, high blood glucose and leukocytes levels are associated with END. Elevated levels of blood markers NSE, IL-6, HsCRP and NT-proBNP indicate poor functional outcome at 90 days after AIS. These patients must be identified and be offered treatment immediately in order to improve the functional outcome after AIS.
Design of 5G millimeter-wave rectangular patch antenna with transmission line feeding and coaxial cable feeding

Huge channel capacity is required in modern and future human communications. In 5G millimeter-wave signal transmission, the type of antenna determines the amount of transmitted signal to some extent. For different kinds of antennas, patch antenna is widely used in mobile devices such as smart phone in terms of low-profile and cheap manufacture. Despite relatively narrow bandwidth, patch array antenna has ameliorated this disadvantage by using tunable excitation amplitudes and phases. This paper mainly studies the performance of a single patch antenna with substrate Rogers 5880 operating in millimeter-wave channel n259 to explore the design principles of patch antennas. The three-layer structure of antenna and the calculation process of antenna dimensions, which are patch size and substrate thickness, are introduced. Two feeding methods which transmission line feeding and coaxial cable feeding are separately simulated in CST Studio software, and then their performance especially the gain of far-field radiation pattern in E-plane are compared. Both of these two feeding methods display favorable performance. However, coaxial cable feed antenna behaviors better because of less propagation loss.
Building bridges, not walls: exploring the environmental education ecosystem

If you are reading this, there is a strong chance you care about making the world a better place. As academics in higher education, nonprofit professionals, and global citizens, we, too, care about the urgent, interconnected issues facing people and the planet. For more than four decades, we have worked in the environmental, sustainability, arts, evaluation, and education spaces and, among us, have done so in formal, nonformal, and informal settings. Moreover, in addition to the varied identities that we bring to our work, we recognize ourselves as environmental education (EE) professionals, agreeing with Monroe et al. (2008) who say that EE is a philosophy, approach, tool, and profession. Strengthening this profession through enhancing its efficacy, relevance, and ability to make change in the world requires augmenting connections with related professions and disciplines, for the benefit of all.
Transcriptome-Wide Detection of Intron/Exon Definition in the Endogenous Pre-mRNA Transcripts of Mammalian Cells and Its Regulation by Depolarization

Pairing of splice sites across an intron or exon is the central point of intron or exon definition in pre-mRNA splicing with the latter mode proposed for most mammalian exons. However, transcriptome-wide pairing within endogenous transcripts has not been examined for the prevalence of each mode in mammalian cells. Here we report such pairings in rat GH3 pituitary cells by measuring the relative abundance of nuclear RNA-Seq reads at the intron start or end (RISE). Interestingly, RISE indexes are positively correlated between 5′ and 3′ splice sites specifically across introns or exons but inversely correlated with the usage of adjacent exons. Moreover, the ratios between the paired indexes were globally modulated by depolarization, which was disruptible by 5-aza-Cytidine. The nucleotide matrices of the RISE-positive splice sites deviate significantly from the rat consensus, and short introns or exons are enriched with the cross-intron or -exon RISE pairs, respectively. Functionally, the RISE-positive genes cluster for basic cellular processes including RNA binding/splicing, or more specifically, hormone production if regulated by depolarization. Together, the RISE analysis identified the transcriptome-wide regulation of either intron or exon definition between weak splice sites of short introns/exons in mammalian cells. The analysis also provides a way to further track the splicing intermediates and intron/exon definition during the dynamic regulation of alternative splicing by extracellular factors.