Miracle-dz/UniFAR-FTUs huggingface dataset:
Galoisian approach to supersymmetric quantum mechanics

Esta tesis versa sobre el punto de vista desde la Teoría de Galois Diferencial hacia la mecánica cuántica supersimétrica. El objeto principal considerado aquí es la ecuación deSchrödinger estacionaria no relativista, especialmente los casos integrables en el sentido de la teoría de Picard-Vessiot theory y las principales herramientas algorítmicas utilizadas aquí son el algoritmo de Kovacic y el método de la algebrización para obtener ecuaciones diferenciales lineales con coeficientes racionales. Analizamos las transformaciones de Darboux, la iteración de Crum y la mecánica cuántica supersimétrica con sus versiones algebrizadas desde un acercamiento Galoisiano. Aplicando el método de la algebrización y el algoritmo de Kovacic obtenemos el estado base, las funciones propias, los valores propios los grupos de Galois diferenciales y los anillos propios de algunas ecuaciones de Schrödinger con potenciales tales como exactamente resoluble y potenciales de forma invariante. Finalmente, introducimos una metodología para buscar potenciales exactamente resolubles. Para construir otros potenciales, aplicamos el método de la algebrización en forma inversa, desde ecuaciones diferenciales que tengan polinomios ortogonales y funciones especiales como soluciones
The soot handling ability requirements and how to solve soot related viscosity increases of heavy duty diesel engine oil

Purpose The purpose of this paper is to identify the feature of soot in diesel engine oil and provide a method to stably disperse these soots using effect additives which is benefical for lubricants to pass related engine tests. Design/methodology/approach This paper designed experiments to investigate the dispersant type, treat level and different dispersant interactions which influence on lubricant soot-related viscosity increase. The research work developed an effective dispersant package which can well solve the soot-related viscosity increase, allowing pass Mack T-11 and Mack T-8 engine tests and demonstrated the helpfulness of using a quickly screening method developed by a steel piston diesel engine CA 6DL2-35. Findings The effect of dispersant treat level on the viscosity increase of the oil samples was negligible. Dispersant booster can effectively improve the soot handling ability of heavy-duty diesel engine oils (HDDEO), and the appropriate treat level of dispersant booster can help HDDEO pass Mack T-8 and Mack T-11 engine tests. Practical implications The test results are useful for formulators to select the appropriate dispersants or dispersant booster to develop the HDDEO packages which can meet the modern diesel engine lubrication requirements. Originality/value Most previous studies in this field were carried out on soot formation mechanism and soot-related wear rather than how to solve the soot-related viscosity increasing of HDDEO. This paper describes the soot dispersing requirements of different HDDEO specifications and developed an effective dispersant package which can well deal with Mack T-11 and Mack T-8E standard engine tests soot handling ability requirements.
Recurrent and symbiotic novae in data from the Optical Gravitational Lensing Experiment

We analyse long-term optical photometry for two Galactic recurrent novae (V745 Sco and V3890 Sgr) and one Large Magellanic Cloud object (Nova LMC 1990b) observed over several years by the Optical Gravitational Lensing Experiment (OGLE) sky survey. We do not find variability with the previously claimed orbital period of V745 Sco. This voids previous findings based on this value (e.g. the distance determination). The quiescence variability of this object is dominated by semiregular pulsations of the red giant secondary (with periods of 136.5 and 77.4 d). The photometry of Nova LMC 1990b reveals an unnoticed eruption in 2010 and eclipse-like variability in quiescence with a period of 1.26432(8) d. The photometric properties make this object very similar to U Sco. Finally, we describe the eruptions of two likely symbiotic novae, V5590 Sgr and OGLE-2011-BLG-1444. The secondary of V5590 Sgr is a Mira star with pulsation period of 236 d.
Modeling the Influence of the Penetration Channel’s Shape on Plasma Parameters When Handling Highly Concentrated Energy Sources

In our work to formulate a scientific justification for process control methods when processing materials using concentrated energy sources, we develop a model that can calculate plasma parameters and the magnitude of the secondary waveform of a current from a non-self-sustained discharge in plasma as a function of the geometry of the penetration channel, thermal fields, and the beam’s position within the penetration channel. We present the method and a numeric implementation whose first stage involves the use of a two-dimensional model to calculate the statistical probability of the secondary electrons’ passage through the penetration channel as a function of the interaction zone’s depth. Then, the discovered relationship is used to numerically calculate how the secondary current changes as a distributed beam moves along a three-dimensional penetration channel. We demonstrate that during oscillating electron beam welding the waveform has the greatest magnitude during interaction with the upper areas of the penetration channel and diminishes with increasing penetration channel depth in a way that depends on the penetration channel’s shape. When the surface of the penetration channel is approximated with a Gaussian function, the waveform decreases nearly exponentially.
Conditions for existence and smoothness of the distribution density for an Ornstein-Uhlenbeck process with Levy noise

Conditions are given, sufficient for the distribution of an Ornstein-Uhlenbeck process with L\'evy noise to be absolutely continuous or to possess a smooth density. For the processes with non-degenerate drift coefficient, these conditions are a necessary ones. A multidimensional analogue for the non-degeneracy condition on the drift coefficient is introduced.
Search for a new charged heavy vector boson decaying to an electron-neutrino pair in p$\bar{p}$ collisions at √s = 1.96 TeV

We present results on a search for a heavy charged vector boson, W', decaying to an electron-neutrino pair in p{bar p} collisions at {radical}s = 1.96 TeV using a data sample corresponding to an integrated luminosity of 205 pb{sup -1}. We found no evidence of this decay channel, and set 95% confidence level limits on the production cross section times branching fraction assuming the light neutrino. We also set the limit on the W' boson mass at M{sub W'} > 788 GeV/c{sup 2}, assuming the standard model strength couplings.
Are superficial neuromasts proprioceptors underlying fast copulatory behavior?

In male Poeciliid fishes, the modified anal fin (i.e., gonopodium) and its axial and appendicular support are repositioned within the axial skeleton, creating a novel sexually dimorphic ano-urogenital region. During copulation, the relative location of the gonopodium is crucial for successful insemination. Therefore, the repositioning of these structures and organ relied on the reorganization of the efferent circuitry that controls spinal motor neurons innervating appendicular muscles critical for the movement of the gonopodium, including the fast and synchronous torque-trust motion during insemination attempts. Copulation occurs when a male positions himself largely outside a female’s field of view, circumducts his gonopodium, and performs a rapid, complex maneuver to properly contact the female urogenital sinus with the distal tip of the gonopodium and transfers sperm. Although understanding of the efferent circuitry has significantly increased in the last 24 years, nothing is known about the cutaneous receptors involved in gonopodium movement, or how the afferent signals are processed to determine the location of this organ during copulation. Using Western mosquitofish, Gambusia affinis, as our model, we attempt to fill this gap in knowledge. Preliminary data showed cutaneous nerves and sensory neurons innervating superficial neuromasts surrounding the base of adult male gonopodium; those cutaneous nerves projected ventrally from the spinal cord through the 14th dorsal root ganglion and its corresponding ventral root towards the base and fin rays of the gonopodium. We asked what role the cutaneous superficial neuromasts play in controlling the positioning and timing of the gonopodium’s fast and synchronous movements for effective sperm transfer. First, we found a greater number of superficial neuromasts surrounding the base of the male’s gonopodium compared to the base of the female’s anal fin. Second, we systemically removed superficial neuromasts surrounding the gonopodium base and observed significant impairment of the positioning and timing of gonopodial movements. Our findings provide a first step to supporting the following hypothesis: during radical reorganization of the Poeciliid body plan, superficial neuromasts have been partially co-opted as proprioceptors that allow the gonopodium to control precise positioning and timing during copulatory attempts.
Research progress on the pharmacological effects of matrine

Matrine possesses anti-cancer properties, as well as the prevention and treatment of allergic asthma, and protection against cerebral ischemia-reperfusion injury. Its mechanism of action may be (1) regulation of cancer cell invasion, migration, proliferation, and cell cycle to inhibit tumor growth; (2) reduction of oxidized low-density lipoprotein and advanced glycation end products from the source by exerting anti-inflammatory and antioxidant effects; (3) protection of brain damage and cortical neurons by regulating apoptosis; (4) restoration of the intestinal barrier and regulation of the intestinal microbiota. This article aims to explore matrine’s therapeutic potential by summarizing comprehensive information on matrine’s pharmacology, toxicity, and bioavailability.
Krill biomass estimation: Sampling and measurement variability

Krill are the subject of growing commercial fisheries and therefore fisheries management is necessary to ensure long-term sustainability. Krill catch limits, set by Commission for the Conservation of Antarctic Marine Living Resources, are based on absolute krill biomass, estimated from acoustic-trawl surveys. In this work, we develop a method for determining an error budget for acoustic-trawl surveys of krill which includes sampling and measurement variability. We use our error budget method to examine the sensitivity of biomass estimates to parameters in acoustic target strength (TS) models, length frequency distribution and length to wetmass relationships derived from net data. We determined that the average coefficient of variation (CV) of estimated biomass was 17.7% and the average CV due from scaling acoustic observations to biomass density was 5.3%. We found that a large proportion of the variability of biomass estimates is due to the krill orientation distribution, a parameter in the TS model. Orientation distributions with narrow standard deviations were found to emphasise the results of nulls in the TS to length relationship, which has to potential to lead to biologically implausible results.
Antifungal activity of non-conventional yeasts against Botrytis cinerea and non-Botrytis grape bunch rot fungi

Grapes harbour a plethora of non-conventional yeast species. Over the past two decades, several of the species have been extensively characterised and their contribution to wine quality is better understood. Beyond fermentation, some of the species have been investigated for their potential as alternative biological tools to reduce grape and wine spoilage. However, such studies remain limited to a few genera. This work aimed to evaluate the antagonistic activity of grape must-derived non-conventional yeasts against Botrytis cinerea and non-Botrytis bunch-rotting moulds and to further elucidate mechanisms conferring antifungal activity. A total of 31 yeast strains representing 21 species were screened on different agar media using a dual culture technique and liquid mixed cultures, respectively. Pichia kudriavzevii was the most potent with a minimum inhibitory concentration of 102 cells/mL against B. cinerea but it had a narrow activity spectrum. Twelve of the yeast strains displayed broad antagonistic activity, inhibiting three strains of B. cinerea (B05. 10, IWBT FF1 and IWBT FF2), a strain of Aspergillus niger and Alternaria alternata. Production of chitinases and glucanases in the presence of B. cinerea was a common feature in most of the antagonists. Volatile and non-volatile compounds produced by antagonistic yeast strains in the presence of B. cinerea were analysed and identified using gas and liquid chromatography mass spectrometry, respectively. The volatile compounds identified belonged mainly to higher alcohols, esters, organosulfur compounds and monoterpenes while the non-volatile compounds were cyclic peptides and diketopiperazine. To our knowledge, this is the first report to demonstrate inhibitory effect of the non-volatile compounds produced by various yeast species.
Investigation of Bias Errors in Laser Doppler Velocimeter Measurements.

Abstract : The problem of velocity bias laser Doppler Velocimeter (LDV) measurements made with counter type (burst) signal processors in turbulent flows was investigated. By using a signal processing technique which allowed velocity samples to be taken either randomly or at equal time intervals, the magnitude of the velocity bias was directly measured under various flow conditions. Using this technique, the validity of the one-dimensional velocity weighting correction of McLaughlin an Tiederman was investigated and found to be useful only at turbulence intensities below about 20 percent. Incomplete signal bias was also investigated and found to cause serious errors in unshifted LDV measurements. However, this bias may be virtually eliminated by frequency shifting. (Author)
Experimental treatments to attenuate blood spinal cord barrier rupture in rats with traumatic spinal cord injury: A meta-analysis and systematic review

Background: Traumatic spinal cord injury (t-SCI) is a severe injury that has a devastating impact on neurological function. Blood spinal cord barrier (BSCB) destruction following SCI aggravates the primary injury, resulting in a secondary injury. A series of experimental treatments have been proven to alleviate BSCB destruction after t-SCI. Methods: From a screen of 1,189 papers, which were retrieved from Pubmed, Embase, and Web of science, we identified 28 papers which adhered to strict inclusion and exclusion criteria. Evans blue (EB) leakage on the first day post-SCI was selected as the primary result. Secondary outcomes included the expression of tight junction (TJ) proteins and adhesion junction (AJ) proteins in protein immunoblotting. In addition, we measured functional recovery using the Basso, Beattie, Besnahan (BBB) score and we analyzed the relevant mechanisms to explore the similarities between different studies. Result: The forest plot of Evans blue leakage (EB leakage) reduction rate: the pooled effect size of the 28 studies was 0.54, 95% CI: 0.47–0.61, p < 0.01. This indicates that measures to mitigate BSCB damage significantly improved in reducing overall EB leakage. In addition TJ proteins (Occludin, Claudin-5, and ZO-1), AJ proteins (P120 and β-catenin) were significantly upregulated after treatment in all publications. Moreover, BBB scores were significantly improved. Comprehensive studies have shown that in t-SCI, inhibition of matrix metalloproteinases (MMPs) is the most commonly used mechanism to mitigate BSCB damage, followed by endoplasmic reticulum (ER) stress and the Akt pathway. In addition, we found that bone marrow mesenchymal stem cell-derived exosomes (BMSC-Exos), which inhibit the TIMP2/MMP signaling pathway, may be the most effective way to alleviate BSCB injury. Conclusion: This study systematically analyzes the experimental treatments and their mechanisms for reducing BSCB injury in the early stage of t-SCI. BMSC-Exos, which inhibit MMP expression, are currently the most effective therapeutic modality for alleviating BSCB damage. In addition, the regulation of MMPs in particular as well as the Akt pathway and the ER stress pathway play important roles in alleviating BSCB injury. Systematic Review Registration: https://www.crd. york.ac. uk/prospero/display_record. php? ID=CRD42022324794.
Twelve-month outcomes in overweight/obese users with mental disorders following a multi-element treatment including diet, physical activity, and positive thinking: The real-world “An Apple a Day” controlled trial

The present study aimed to evaluate the 12-month effectiveness of a real-world weight loss transdiagnostic intervention in overweight/obese participants affected by mental disorders under psychopharmacological treatment. We conducted a real-world, controlled, pragmatic outpatient trial. We allocated 58 overweight/obese adults under psychopharmacological treatment from a mental health outpatient unit and 48 overweight/obese adults from a cardiovascular prevention outpatient unit, and assigned them to an intervention or treatment usual as condition (TAU) enriched by life-style advice. Participants in both intervention groups took part in a diet programme (the modified OMNIHeart dietary protocol) and monitoring of regular aerobic activity. A brief group programme (“An Apple a Day” Metacognitive Training, Apple-MCT) was added in the intervention group of participants affected by mental disorders. The primary outcome was weight loss. Secondary outcomes included anthropometric, clinical, and metabolic variables. Psychopathology and health-related quality of life were also evaluated in the psychiatric sample. At 12 months, both intervention groups showed a more marked mean decrease in weight (6.7 kg, SD: 3.57) than the TAU group (0.32 kg, SD: 1.96), and a statistically significant improvement in metabolic variables compared with the control groups. Furthermore, the participants affected by mental disorders included in the intervention group reported improved health-related quality of life. Our findings suggest the need to implement integrated interventions based on a dietary protocol, physical activity, and modification of cognitive style in overweight/obese users with mental disorders.
Quality monitoring of intellectual and developmental disabilities systems in the US: Assessing the utility and applicability of selected National Core Indicators to national and state priorities

This article provides historical context on the evolution of performance measures for system improvement, examines the perspectives and insights of state public managers on the use and utility of NQF-endorsed outcome measures from the NCI®-IDD In-Person Survey (IPS) for quality improvement, and discusses the necessity of ensuring that outcome measures align with public policy goals.
Enhancing spiking neural networks with hybrid top-down attention

As the representatives of brain-inspired models at the neuronal level, spiking neural networks (SNNs) have shown great promise in processing spatiotemporal information with intrinsic temporal dynamics. SNNs are expected to further improve their robustness and computing efficiency by introducing top-down attention at the architectural level, which is crucial for the human brain to support advanced intelligence. However, this attempt encounters difficulties in optimizing the attention in SNNs largely due to the lack of annotations. Here, we develop a hybrid network model with a top-down attention mechanism (HTDA) by incorporating an artificial neural network (ANN) to generate attention maps based on the features extracted by a feedforward SNN. The attention map is then used to modulate the encoding layer of the SNN so that it focuses on the most informative sensory input. To facilitate direct learning of attention maps and avoid labor-intensive annotations, we propose a general principle and a corresponding weakly-supervised objective, which promotes the HTDA model to utilize an integral and small subset of the input to give accurate predictions. On this basis, the ANN and the SNN can be jointly optimized by surrogate gradient descent in an end-to-end manner. We comprehensively evaluated the HTDA model on object recognition tasks, which demonstrates strong robustness to adversarial noise, high computing efficiency, and good interpretability. On the widely-adopted CIFAR-10, CIFAR-100, and MNIST benchmarks, the HTDA model reduces firing rates by up to 50% and improves adversarial robustness by up to 10% with comparable or better accuracy compared with the state-of-the-art SNNs. The HTDA model is also verified on dynamic neuromorphic datasets and achieves consistent improvements. This study provides a new way to boost the performance of SNNs by employing a hybrid top-down attention mechanism.
Activation of the NFκB signaling pathway in IL6+CSF3+ vascular endothelial cells promotes the formation of keloids

Background: Keloid is a disease caused by abnormal proliferation of skin fibres, the causative mechanism of which remains unclear. Method: In this study, endothelial cells of keloids were studied using scRNAseq combined with bulk-RNAseq data from keloids. The master regulators driving keloid development were identified by transcription factor enrichment analysis. The pattern of changes in vascular endothelial cells during keloid development was explored by inferring endothelial cell differentiation trajectories. Deconvolution of bulkRNAseq by CIBERSORTX verified the pattern of keloidogenesis. Immunohistochemistry for verification of the lesion process in keloid endothelial cells. Results: The endothelial cells of keloids consist of four main cell populations (MMP1+ Endo0, FOS + JUN + Endo1, IL6+CSF3+Endo2, CXCL12 + Endo3). Endo3 is an endothelial progenitor cell, Endo1 is an endothelial cell in the resting state, Endo2 is an endothelial cell in the activated state and Endo0 is an endothelial cell in the terminally differentiated state. Activation of the NFΚB signaling pathway is a typical feature of Endo2 and represents the early skin state of keloids. Conclusion: We have identified patterns of vascular endothelial cell lesions during keloidogenesis and development, and have found that activation of the NFΚB signaling pathway is an essential feature of keloid formation. These findings are expected to contribute to the understanding of the pathogenesis of keloids and to the development of new targeted therapeutic agents for the lesional characteristics of vascular endothelial cells.
Spatial spillover effect of industrial structure upgrading on carbon emission intensity: panel data evidences from Beijing, China

Applying the panel data of 16 districts in Beijing, China from 2009 to 2020 as the research object, this study measures and analyzes the carbon emission intensity and the level of industrial structure upgrading. Based on the above results, a spatial econometric model is established to analyze the spatial spillover effect of industrial structure upgrading on carbon emission intensity. Conclusions are drawn as follows: (a) In 2009, 2015 and 2020, the carbon emission intensity in most districts of Beijing has decreased, and in some areas even decreased significantly. The upgrading of industrial structure in all districts has been improved (b). According to the results of spatial autocorrelation, the carbon emission intensity in Beijing shows significant positive spatial autocorrelation in 2009 and 2020, while negative spatial autocorrelation in 2015; The upgrading of industrial structure in Beijing shows significant positive spatial autocorrelation in 2009, 2015 and 2020 (c). The regression results of the spatial econometric model show that industrial structure upgrading not only reduces the carbon emission intensity of the region, but also decreases the carbon emission intensity of the surrounding areas.