Miracle-dz/UniFAR-FTUs huggingface dataset:
Evaluation of the Cross-Protective Efﬁcacy of a Chimeric Porcine Reproductive and Respiratory Syndrome Virus Constructed Based on Two Field Strains

: One of the major hurdles to porcine reproductive and respiratory syndrome (PRRS) vaccinology is the limited or no cross-protection conferred by current vaccines. To overcome this challenge, a PRRS chimeric virus (CV) was constructed using an FL12-based cDNA infectious clone in which open reading frames (ORFs) 3–4 and ORFs 5–6 were replaced with the two Korean ﬁeld isolates K08-1054 and K07-2273,respectively. This virus was evaluated as a vaccine candidate to provide simultaneous protection against two genetically distinct PRRS virus (PRRSV) strains. Thirty PRRS-negative three-week-old pigs were divided into ﬁve groups and vaccinated with CV, K08-1054, K07-2273, VR-2332, or a mock inoculum. At 25 days post-vaccination (dpv), the pigs in each group were divided further into two groups and challenged with either K08-1054 or K07-2273. All of the pigs were observed until 42 dpv and were euthanized for pathological evaluation. Overall, the CV-vaccinated group exhibited higher levels of tumor necrosis factor-alpha (TNF-α ), interferon-gamma (IFN-γ ), and interleukin-12 (IL-12) expression and of serum virus-neutralizing antibodies compared with the other groups after vaccination and also demonstrated better protection levels against both viruses compared with the challenge control group. Based on these results, it was concluded that CV might be an effective vaccine model that can confer a broader range of cross-protection to various PRRSV strains.
THE RELATIONSHIP BETWEEN PEER SOCIAL SUPPORT AND SUBJECTIVE WELFARE IN VIEW OF GENDER OF VOCATIONAL HIGH SCHOOL STUDENTS

The purpose of this study was to determine the relationship between peer social support and subjective well-being in terms of the gender of SMK students in Tanjung Morawa. In this study using an explanatory quantitative approach. A sample of 192 based on random sampling technique. Using two psychological scales, namely the scale of subjective well-being and peer social support. In processing the data used normality test, linearity test, and hypothesis testing. The results showed that there was a significant relationship between peer social support and students' subjective well-being. The higher the peer social support, the higher the subjective well-being, and vice versa. There is no significant difference in subjective well-being between male and female students. This states that both male and female students have the same level of subjective well-being. It is hoped that the school can improve the subjective well-being of students by increasing the social support of students' peers, through entering the community they want, providing space to talk to friends, holding school vent events and other activities. Students are expected to be able to improve subjective well-being by: getting involved in school sharing events, communicating feelings and emotions in various situations such as feeling pleasant, having positive expectations in the learning process, entering the community they want. It is hoped that the school can improve the subjective well-being of students by increasing the social support of students' peers, through entering the community they want, providing space to talk to friends, holding school vent events and other activities. Students are expected to be able to improve subjective well-being by: getting involved in school sharing events, communicating feelings and emotions in various situations such as feeling pleasant, having positive expectations in the learning process, entering the community they want. It is hoped that the school can improve the subjective well-being of students by increasing the social support of students' peers, through entering the community they want, providing space to talk to friends, holding school vent events and other activities. Students are expected to be able to improve subjective well-being by: getting involved in school sharing events, communicating feelings and emotions in various situations such as feeling pleasant, having positive expectations in the learning process, entering the community they want.
What are the determinants of antiretroviral therapy adherence among people living with HIV? A cross-sectional study in Cambodia

Background Understanding context-specic determinants of antiretroviral therapy (ART) adherence is crucial for developing tailored interventions for improving health outcomes and achieving the UNAIDS’ third 95% target. This cross-sectional study explores factors associated with ART adherence among stable people living with HIV on ART in Cambodia. Methods We used baseline cross-sectional survey data from a quasi-experimental study conducted in 2021. The participants were recruited from 20 ART clinics in nine provinces for face-to-face interviews. A structured questionnaire collected information on sociodemographic characteristics, ART adherence, perceived ART self-ecacy, mental health, quality of life, stigma
MIT Open Access Articles PRAC: Exploiting partial packets without cross-layer or feedback information

—This paper proposes a partial packet recovery scheme, called Packetized Rateless Algebraic Consistency (PRAC). PRAC exploits intra and inter-packet consistency to identify and recover erroneous packet segments, without recourse to cross-layer or detailed feedback information. In the absence of cross-layer coordination or detailed feedback, the prevailing methods proposed in the literature have discarded packets with errors. PRAC uses a rateless linear packet code for data encoding and an iterative decoding process consisting of a search algorithm and an algebraic consistency rule (ACR) check. It allows, but not relies upon, the use of any PHY FEC code, requires no feedback other than a notiﬁcation of completion and, in the absence of partial packets, incurs no overhead. Our implementation and experimental results in a 7-node indoor testbed using wireless boards equipped with CC2500 radio transceivers reveal that PRAC offers an average throughput gain of 35 % compared to a baseline ARQ scheme discarding partial packets and 13 % compared to an ideal genie-aided HARQ (iHARQ) scheme. Speciﬁcally for links with high PERs, PRAC signiﬁcantly enhances their robustness and its maximum throughput gain is 148 % and 34 % compared against the baseline and iHARQ schemes, respectively.
The ‘Golden Generations’ in Historical Context

ABSTRACT Assumptions about future mortality are more important than those for factors such as fertility, migration, disability trends or real interest rates for cost projections of the U.S. Old Age, Survivors, Disability and Health Insurance scheme. Recently, one factor has been assumed to be the key driver of future mortality in both official British population projections and actuarial ones: a ‘cohort effect’ associated with a group who were born in a period centred on the early 1930s who have been identified as having experienced particularly rapid improvements in mortality rates and are often referred to as the ‘golden generations’ or ‘golden cohorts’. The concept of ‘cohort effects’ is discussed; limitations of national-level cohort data considered; and methods for identifying such effects are reviewed. Particular attention is given to the analysis of populations which have been identified as having clear cut cohort effects; those of Britain and Sweden in the later part of the nineteenth century and early twentieth century, as well as the contemporary British population. The likely magnitude of such effects is discussed using a stylised model to assess the extent to which members of the ‘golden generations’ are especially privileged.
F.: Situation-Based Knowledge Presentation for Mobile Workers

Knowledge Management services enabling CSCW (Computer Supported Cooperative Work) applications to provide an appropriate adaptation to the user and the situation in which the user is working. In this paper, we explain how a knowledge management system can be designed to support users in different situations exploiting contextual data, users' preferences, and profiles of involved artifacts The presented work roots in the experience we had in the MILK project and early steps made in the MAIS project.
Effects of PMSG and the prostaglandin F-2\g=a\analogue, cloprostenol, on superovulation, fertilization and egg transport in the ewe

Summary. Romney ewes were artificially inseminated at the oestrus after treatment with PMSG on Day 12 of the cycle, Cloprostenol on Day 14, or both. PMSG resulted in increased numbers of ovulations and large follicles but Cloprostenol had no effect alone or with PMSG. PMSG and Cloprostenol alone led to reduced proportions of eggs fertilized, and PMSG also reduced the proportion of ewes with fertilized eggs. The distribution of eggs in the reproductive tract indicated more rapid egg transport in ewes treated with PMSG. A greater proportion of eggs was recovered from the uterus in ewes in which oestrus was first detected at night. Cloprostenol, as administered to PMSG-treated ewes in this trial, offered no advantage for the preparation of donor ewes for egg transfer.
IFPNet: Integrated Feature Pyramid Network with Fusion Factor for Lane Detection

Lane detection is a basic but challenging task in autonomous driving systems. With a combination of high-level and low-level information, early studies of lane detection have achieved promising results in some scenes. However, achieving better performance is still an urgent need for complex and diverse road conditions. We assume that learning and balancing the finer-scale features and global semantics is one of the keys to improving lane detection performance under these road conditions. In this paper, we propose an integrated feature pyramid network with fusion factor (IFPNet) for better hierarchical information learning and balancing, where a novel FPN structure named Integrated Feature Pyramid (IFP) is proposed for better hierarchical information integration. Classification Fusion Factor (CFF) is also utilized for the balance of hierarchical information. Moreover, we design the regression IoU (RIoU) loss for curve regression, which measures the overlap of the predicted and ground truth lane lines more effectively. We conduct experiments on three benchmark datasets of lane detection and achieve state-of-the-art results with high accuracy and efficiency.
Altered diastolic function and aortic stiffness in Alzheimer’s disease

Background: Alzheimer’s disease (AD) is closely linked to cardiovascular risk factors. Methods: Echocardiographic studies were performed, including left ventricular diastolic functions, left and right atrial conduction times, and arterial stiffness parameters, namely stiffness index, pressure-strain elastic modulus, and distensibility, on 29 patients with AD and 24 age-matched individuals with normal cognitive function. Results: The peak mitral flow velocity of the early rapid filling wave (E) was lower, and the peak velocity of the late filling wave caused by atrial contraction (A), deceleration time of peak E velocity, and isovolumetric relaxation time were higher in the AD group. The early myocardial peak (E a ) velocity was significantly lower in AD patients, whereas the late diastolic (A a ) velocity and E/E a ratio were similar between the two groups. In Alzheimer patients, stiffness index and pressure-strain elastic modulus were higher, and distensibility was significantly lower in the AD group compared to the control. Interatrial electromechanical delay was significantly longer in the AD group. Conclusion: Our findings suggest that patients with AD are more likely to have diastolic dysfunction, higher atrial conduction times, and increased arterial stiffness compared to the controls of same sex and similar age. diabetes, stroke, and atherosclerosis. 3–7 Some studies have investigated the parameters of arterial stiffness in patients with dementia. 8–11 It has been observed that patients with AD have structural and functional heart abnormalities, including subclinical impairment of cardiac structure and function, aortic valve thickening, aortic regurgitation, and left ventricular (LV) wall motion abnormalities. 12 In this study, our objective was to examine the LV diastolic parameters, atrial conduction times, and aortic stiffness parameters by conventional echocardiography in patients with and without AD.
Atmospheric Convection

ABSTRACT Convective parameterization is the long-lasting bottleneck of global climate modelling and one of the most difficult problems in atmospheric sciences. Uncertainty in convective parameterization is the leading cause of the widespread climate sensitivity in IPCC global warming projections. This paper reviews the observations and parameterizations of atmospheric convection with emphasis on the cloud structure, bulk effects, and closure assumption. The representative state-of-the-art convection schemes are presented, including the ECMWF convection scheme, the Grell scheme used in NCEP model and WRF model, the Zhang-MacFarlane scheme used in NCAR and DOE models, and parameterizations of shallow moist convection. The observed convection has self-suppression mechanisms caused by entrainment in convective updrafts, surface cold pool generated by unsaturated convective downdrafts, and warm and dry lower troposphere created by mesoscale downdrafts. The post-convection environment is often characterized by “diamond sounding” suggesting an over-stabilization rather than barely returning to neutral state. Then the pre-convection environment is characterized by slow moistening of lower troposphere triggered by surface moisture convergence and other mechanisms. The over-stabilization and slow moistening make the convection events episodic and decouple the middle/upper troposphere from the boundary layer, making the state-type quasi-equilibrium hypothesis invalid. Right now, unsaturated convective downdrafts and especially mesoscale downdrafts are missing in most convection schemes, while some schemes are using undiluted convective updrafts, all of which favour easily turned-on convection linked to double-ITCZ (inter-tropical convergence zone), overly weak MJO (Madden-Julian Oscillation) and precocious diurnal precipitation maximum. We propose a new strategy for convection scheme development using reanalysis-driven model experiments such as the assimilation runs in weather prediction centres and the decadal prediction runs in climate modelling centres, aided by satellite simulators evaluating key characteristics such as the lifecycle of convective cloud-top distribution and stratiform precipitation fraction.
GERONTOCRACY IN RELIGIOUSLY PLURAL NIGERIAN SOCIETIES: A TOOL FOR LAND MANAGEMENT

Gerontocracy is a system of government in which the eldest members of the kindred leads and makes decision on behalf of the kindred or clan in primordial societies particularly in Africa. One of the areas in which the leadership of the elders is most sought is in the area of land acquisition. Unt il recently no one gets access to land without the collective consent of the elders’ council. However with the enactment of the land use decree in Nigeria, government agencies and multinational companies have sought access to vast areas of family land with out passing through the elders, but instead using the provisions of the land use decree, obtaining certificates of occupancy of land belonging to family men and women. This article seeks to re -assess the more dependable role played by the elders in the pa st which helped to stabilize the land economy in Nigeria in view of the present confusion created in this area by the activities of unscrupulous land speculators and misinformed bureaucrats. It recommends that the land use decree should be modified to inc orporate the system of gerontocracy whereby no one gains access to property belonging to others without the due and informed consent of the owners of such property.
In-silico calculation of soil pH by SCEPTER v1.0

One of the soil properties most commonly measured to describe agronomic and biogeochemical conditions of soils is “soil pH”. Soil pH measures the concentration of exchangeable H + that resides in bulk soil samples taken from the 10 field, through aqueous H + measurements of extractants (e.g., deionized water or electrolyte solutions) added to dried bulk soil samples in the laboratory. Therefore, “soil pH” differs from “porewater pH”, the latter of which we define here as an in-situ measure of porewater H + concentration in soil/weathering profiles. The difference between the two pH measurements is often not fully known for a given system but could lead to a misunderstanding of soil conditions if the two measurements are directly compared. Agricultural soils are one of the targeted loci for application of the “Enhanced Rock Weathering” (ERW), 15 a technique aimed at counteracting increasing anthropogenic carbon dioxide from burning fossil fuels, and an increase in pH is thought to be one of key advantages of ERW as this can mitigating soil acidification and secure crop yields. As a result, fully evaluating the biogeochemical and agronomic consequences of ERW approaches requires accurate simulation of both soil pH (pH s ) and porewater pH (pH pw ). This paper presents an updated version of the reactive transport code SCEPTER (Soil Cycles of Elements simulator for Predicting TERrestrial regulation of greenhouse gases), which enables simulation of 20 bulk soil pH measurement in the laboratory in addition to porewater pH as measured in the field along with a more comprehensive representation of cation exchange with solid-phase constituents of bulk soil. We first describe the implementation of cation exchange in the SCEPTER model, then introduce conceptual modelling frameworks enabling the calculation of bulk pH s . The validity of the model is examined through comparison of model results with soil pH measurements from mesocosm experiments of maize production with crushed basalt amendments. Finally, illustrative 25 example simulations are shown demonstrating that a difference between pH s and pH pw can lead to significantly different estimates of carbon capture by ERW for a given targeted pH in cropland systems.
Digital Commons @ East Tennessee State University Digital Commons @ East Tennessee State University

Background: Cardiovascular diseases are currently the leading cause of death in humans. The high mortality of cardiac diseases is associated with myocardial ischemia and reperfusion (I/R). Recent studies have reported that micro-RNAs (miRNAs) play important roles in cell apoptosis. However, it is not known yet whether miR-141-3p contributes to the regulation of cardiomyocyte apoptosis. It has been well established that in vitro hypoxia/reoxygenation (H/R) model can follow in vivo myocardial I/R injury. This study aimed to investigate the effects of miR-141-3p and CHD8 on cardiomyocyte apoptosis following H/R. Results: We found that H/R remarkably reduces the expression of miR-141-3p but enhances CHD8 expression both in mRNA and protein in H9c2 cardiomyocytes. We also found either overexpression of miR-141-3p by transfection of miR-141-3p mimics or inhibition of CHD8 by transfection of small interfering RNA (siRNA) significantly decrease cardiomyocyte apoptosis induced by H/R. Moreover, miR-141-3p interacts with CHD8. Furthermore, miR-141-3p and CHD8 reduce the expression of p21. Conclusion: MiR-141-3p and CHD8 play critical roles in cardiomyocyte apoptosis induced by H/R. These studies suggest that miR-141-3p and CHD8 mediated cardiomyocyte apoptosis may offer a novel therapeutic strategy against myocardial I/R injury-induced cardiovascular diseases.
TURISMO E TERRITÓRIO: A CONTRIBUIÇÃO DAS POLÍTICAS DE TURISMO AO PÓLO VELHO CHICO/SE TOURISM AND TERRITORY: A REFLECTION ON THE INFLUENCE OF POLICIES FOR TOURISM IN POLE OLD CHICO / SE

Tourism policies aimed at the development of territories as polar inducers of tourism, have gained space for discussion in the Brazilian states, as an alternative to socio, economic and environmental development. In Sergipe, the creation of the Polo Old Chico is presented as an insertion or attempt to insert the practices of a tourism policy that will give consistency in the actions envisaged in this policy, which converges with the National Tourism Plan 2007-2010. The study sought to register the how the particularities of the implementation of these actions on the territory-polo encouraged more development in the state. We conclude that this new territorial arrangement will benefit the entire region in which Polo is located and that it will present results of a real and effective practice of public policy in Sergipe .
Proximate composition of the selected new yam cultivars

Proximate composition of the selected new yam cultivars were analysed. The new white yam cultivars used for this study were obtained from African yam barn at Faculty of Agriculture and Natural Resources Management, Ebonyi State University, Abakaliki, Ebonyi State, Nigeria. The new yam tubers were sorted, washed, peeled and sliced with stainless steel knife into 1mm thickness. The slices were soaked in 200 ppm sodium metabisulphate solutions for 10 minutes, drained, and was dried at 60 o C for 48 hours using an oven. It was dry milled into powder using marlex blender (electro line model IS 4780, CM/L 7902804) to obtain the flours. The flours were kept in a high density polyethene bags (HDPE) film and kept in a refrigerator until ready for use. Proximate analyses were done using standard methods. The protein content of the new yam cultivars ranged from 4.76% for flour samples MECC9 RU59 to 6.97 % for flour sample TDR0500491, flour sample MECC9RU 59 had the lowest value of 4.76 %, while flour sample TDR 0500491 had the highest value of 6.97 % for protein content in the column. Statistics showed that significant difference (P<0.05) exist amongst the flour samples for protein content, except for flour samples TDR1100585 and REP1 BED 19 which are not significantly (P>0.05) different from each other. The moisture contents of the new yam cultivars in Table 1 showed that the moisture content ranged from 10.08% for sample TDR 1100492 to 10.67 % for sample REP1 BED 19. Flour sample TDR 1100492 had the lowest value of 10.08 %, while flour sample REP1 BED 19 had the highest value of 10.67 %. Significant difference (P<0.05) exist for the flour samples in Table 1 for moisture contents. Ash content gives an indication of minerals present in a particular food sample and it is very important in many biochemical reactions which aid physiological functioning of major metabolic processes in the human body [9]. The ash contents of the flour sample ranged from 2.03 % for sample REP1 BED8 to 2.43 % for sample TDR0900082. Significant difference (P<0.05) exists amongst the flour samples for ash content. Flour sample REP1 BED8 had the lowest value of 2.03 %, while flour sample TDR0900082 had the highest value of 2.43 % for the ash content. In conclusion, the results from this research indicated that the new yam cultivars are rich in protein and ash contents.