Miracle-dz/UniFAR-FTUs huggingface dataset:
Biodegradable Scaffolds for Vascular Regeneration Based on Electrospun Poly(L-Lactide-co-Glycolide)/Poly(Isosorbide Sebacate) Fibers

Vascular regeneration is a complex process, additionally limited by the low regeneration potential of blood vessels. Hence, current research is focused on the design of artificial materials that combine biocompatibility with a certain rate of biodegradability and mechanical robustness. In this paper, we have introduced a scaffold material made of poly(L-lactide-co-glycolide)/poly(isosorbide sebacate) (PLGA/PISEB) fibers fabricated in the course of an electrospinning process, and confirmed its biocompatibility towards human umbilical vein endothelial cells (HUVEC). The resulting material was characterized by a bimodal distribution of fiber diameters, with the median of 1.25 µm and 4.75 µm. Genotyping of HUVEC cells collected after 48 h of incubations on the surface of PLGA/PISEB scaffolds showed a potentially pro-angiogenic expression profile, as well as anti-inflammatory effects of this material. Over the course of a 12-week-long hydrolytic degradation process, PLGA/PISEB fibers were found to swell and disintegrate, resulting in the formation of highly developed structures resembling seaweeds. It is expected that the change in the scaffold structure should have a positive effect on blood vessel regeneration, by allowing cells to penetrate the scaffold and grow within a 3D structure of PLGA/PISEB, as well as stabilizing newly-formed endothelium during hydrolytic expansion.
Using Sensor Data to Identify Factors Affecting Internal Air Quality within 279 Lower Income Households in Cornwall, South West of England

(1) Background: Poor air quality affects health and causes premature death and disease. Outdoor air quality has received significant attention, but there has been less focus on indoor air quality and what drives levels of diverse pollutants in the home, such as particulate matter, and the impact this has on health; (2) Methods: This study conducts analysis of cross-sectional data from the Smartline project. Analyses of data from 279 social housing properties with indoor sensor data were used to assess multiple factors that could impact levels of particulate matter. T-Tests and Anova tests were used to explore associations between elevated PM2.5 and building, household and smoking and vaping characteristics. Binary logistic regression was used to test the association between elevated particulate matter and self-reported health; (3) Results: Of the multiple potential drivers of the particulate matter investigated, smoking and vaping were significantly associated with mean PM2.5. Following multivariate analysis, only smoking remained significantly associated with higher mean concentrations. Properties in which <15 cigarettes/day were smoked were predicted to have PM2.5 concentrations 9.06 µg/m3 higher (95% CI 6.4, 12.82, p ≤ 0.001) than those in which residents were non-smokers and 11.82 µg/m3 higher (95% CI 7.67, 18.19, p ≤ 0.001) where >15 cigarettes were smoked; (4) Conclusions: A total of 25% of social housing properties in this study experienced levels of indoor PM greater than WHO guideline levels for ambient air pollution. Although there are many factors that impact air quality, in this study the main driver was smoking. This highlights the importance of targeting smoking in indoor environments in future smoking cessation and control policy and practice and of understanding how pollutants interact in the home environment. There is also a need for further research into the impact on indoor air quality of vaping, particularly due to the rise in use and uncertainty of its long-term impact.
Valence-band ordering and magneto-optic exciton fine structure in ZnO

Using first-principles linear muffin-tin orbital density functional band structure calculations, the ordering of the states in the wurtzite ZnO valence-band maximum, split by crystal-field and spin-orbit coupling effects, is found to be ${\ensuremath{\Gamma}}_{7(5)}g{\ensuremath{\Gamma}}_{9(5)}g{\ensuremath{\Gamma}}_{7(1)},$ in which the number in parentheses indicates the parent state without spin-orbit coupling. This results from the negative spin-orbit splitting, which in turn is due to the participation of the Zn $3d$ band. The result is found to be robust even when effects beyond the local density approximation on the Zn $3d$ band position are included. Using a Kohn-Luttinger model parametrized by our first-principles calculations, it is furthermore shown that the binding energies of the excitons primarily derived from each valence band differ by less than the valence-band splittings even when interband coupling effects are included. The binding energies of $n=2$ and $n=1$ excitons, however, are not in a simple $1/4$ ratio. Our results are shown to be in good agreement with the recent magneto-optical experimental data by Reynolds et al. [Phys. Rev. B 60, 2340 (1999)], in spite of the fact that on the basis of these data these authors claimed that the valence-band maximum would have ${\ensuremath{\Gamma}}_{9}$ symmetry. The differences between our and Reynolds' analysis of the data are discussed and arise from the sign of the Land\'e g factor for holes, which is here found to be negative for the upper ${\ensuremath{\Gamma}}_{7}$ band.
Research on the Relationship between Green Low-carbon Transformation and Capital Market Reactions

Green low-carbon transformation can effectively elicit capital market reactions. Based on the annual reports of A-share listed enterprises from 2012 to 2019, this paper defines the green low-carbon transformation behavior of enterprises and uses event analysis to explore the capital market reactions caused by the green low-carbon transformation behavior of enterprises. The results show that the green low-carbon transformation of enterprises can produce significant “announcement” effect, which will bring significant impact effect to the capital market. The results of this paper are still significant after robustness tests for different sectors and different policy shocks. Further investigation shows that the increase in corporate costs and profitability are the key factors that lead to a significant capital market reactions. The research in this paper can provide an important basis for the green low-carbon transformation of enterprises and can further reveal the motivation of green low-carbon transformation of enterprises.
Increased Intracranial Pressure Due to Transverse Sinus Compression by a Meningioma En Plaque

Idiopathic intracranial hypertension (IIH) is defined as raised intracranial pressure of unknown etiology. Looking for underlying causes needs to be undertaken before the diagnosis is confirmed and managed accordingly. We are reporting a rare and unique case of a patient with the clinical diagnosis of idiopathic intracranial hypertension or pseudotumor cerebri. She is not obese and not taking any predisposing medication. Her first magnetic resonance imaging (MRI) and magnetic resonance venogram (MRV) were reported as showing left transverse sinus thrombosis. She was treated with anticoagulation. Her final diagnosis of left transverse sinus compression by a meningioma en plaque (MEP) was finally made with a repeat MRI. A high index of suspicion of unusual causes is important when IIH presents in an atypical patient or with an atypical presentation. The prognosis and management of real IIH and raised intracranial pressure due to other causes are different.
Suppression of high-power microwave dielectric multipactor by resonant magnetic field

Through dynamic calculation and electromagnetic particle-in-cell simulation, high-power microwave dielectric multipactor is discovered to be suppressed by utilizing external dc magnetic field parallel to the surface, perpendicular to the rf field and satisfying the gyrofrequency close to the rf frequency Ω∼ω. It is found that multipactor electrons emitted from the surface can be resonantly accelerated to obtain the impact energy ee higher than the second crossover energy, leading to secondary emission yield lower than one. Besides, the corresponding flight time gets close to the rf period, also the period of the vector Erf×B, resulting in secondary electrons immediately pulled away without multipactoring along the surface. What is more, with the rf field increasing, suppression effect can be further enhanced due to ee rising.
The energy spectrum of 20 keV-20 MeV electrons accelerated in large solar flares

IMP 6, 7, and 8 measurements of the energy spectrum of 20 keV to 20 MeV electrons observed from large solar flares are presented. To minimize propagation effects, only events from flares at W30° to W90° solar longitude are considered. The energy spectra are constructed using the maximum flux observed at each energy. It is shown that these spectra are representative of the spectra of the electrons escaping from the sun over this range of energies. It is found that every event shows the same spectral shape: a double power law with a smooth transition around 100-200 keV and power law exponents of 0.6-2.0 below and 2.4-4.3 above. The more intense the event, the harder the observed spectrum; in certain cases, the spectra are observed to steepen above 3 MeV.
Toward a Numerical Benchmark for Warm Rain Processes

The Kinematic Driver-Aerosol (KiD-A) intercomparison was established to test the hypothesis that detailed warm microphysical schemes provide a benchmark for lower-complexity bulk microphysics schemes. KiD-A is the first intercomparison to compare multiple Lagrangian cloud models (LCMs), size bin-resolved schemes, and double-moment bulk microphysics schemes in a consistent 1D dynamic framework and box cases. In the absence of sedimentation and collision-coalescence, the drop size distributions (DSDs) from the LCMs exhibit similar evolution with expected physical behaviors and good inter-scheme agreement, with the volume mean diameter (Dvol ) from the LCMs within 1 to 5% of each other. In contrast, the bin schemes exhibit non-physical broadening with condensational growth. These results further strengthen the case that LCMs are an appropriate numerical benchmark for DSD evolution under condensational growth. When precipitation processes are included, however, the simulated liquid water path, precipitation rates, and response to modified cloud drop/aerosol number concentrations from the LCMs vary substantially, while the bin and bulk schemes are relatively more consistent with each other. The lack of consistency in the LCM results stems from both the collision-coalescence process and the sedimentation process, limiting their application as a numerical benchmark for precipitation processes. Reassuringly, however, precipitation from bulk schemes, which are the basis for cloud microphysics in weather and climate prediction, is within the spread of precipitation from the detailed schemes (LCMs and bin). Overall, this intercomparison identifies the need for focused effort on the comparison of collision-coalescence methods and sedimentation in detailed microphysics schemes, especially LCMs.
Power-Law Stress and Creep Relaxations of Single Cells Measured by Colloidal Probe Atomic Force Microscopy

We measured stress and creep relaxations of mouse fibroblast cells arranged and cultured on a microarray, by colloidal probe atomic force microscopy (AFM). A hydrophobic monolayer coating of perfluorodecyltrichlorosilane (FDTS) on the surface of colloidal silica beads significantly reduced the adhesion force of live cells, compared with untreated beads. The rheological behaviors of cells were estimated by averaging several relaxation curves of cells measured by the AFM. Longer-time tailing of both stress and creep relaxation curves followed single power-law behavior over a time scale of 60 s, with exponents in the range 0.1–0.4, varying with cells. The results were in good agreement with previous measurements of the frequency-domain rheology of cells using the force modulation mode.
Concurrent radio, infrared, optical and X-ray observations of the nucleus of the Seyfert galaxy NGC 4151

The nucleus of the Seyfert galaxy NGC 4151 was observed during May and June 1977 at X-ray energies from 20 to 200 keV using the high-energy X-ray spectrometer on OSO 8 at radio frequencies of 2695 and 8085. Data were also taken in the visual, and at infrared wavelengths of 1 to 2 microns, and from 2 to 6 keV using the OSO 8 proportional counter. Optical data showed variability by a factor of 2 within the observing period, which is comparable to the variability in the 2 to 6 keV X-ray flux. No variability, however, was measured at infrared or radio frequencies. The composite spectrum from radio to gamma-ray is plotted, and it is found that the optical and X-ray fluxes varied during the observing period, although it is not known if they varied concurrently.
Semiclassical analysis of the Efimov energy spectrum in the unitary limit

We demonstrate that the (s-wave) geometric spectrum of the Efimov energy levels in the unitary limit is generated by the radial motion of a primitive periodic orbit (and its harmonics) of the corresponding classical system. The action of the primitive orbit depends logarithmically on the energy. It is shown to be consistent with an inverse-squared radial potential with a lower cutoff radius. The lowest-order WKB quantization, including the Langer correction, is shown to reproduce the geometric scaling of the energy spectrum. The (WKB) mean-squared radii of the Efimov states scale geometrically like the inverse of their energies. The WKB wave functions, regularized near the classical turning point by Langer's generalized connection formula, are practically indistinguishable from the exact wave functions even for the lowest (n=0) state, apart from a tiny shift of its zeros that remains constant for large n.
Drops sliding down an incline at large contact line velocity: What happens on the road towards rolling?

Abstract Drops sliding down an incline exhibit fascinating shapes, which indirectly provide a great deal of information about wetting dynamics. Puthenveettil, Kumar & Hopfinger (J. Fluid Mech., vol. 726, 2013, pp. 26–61) have renewed this subject by considering water and mercury drops sliding at high speed. The results raise puzzling questions: how to take into account inertia at a high-speed contact line, large contact angles, the nature of the dissipation at small scale and sliding versus rolling behaviours?
Increased discharge of Yellow River sediments into the western Bohai Sea since 0.71 Ma

Abstract The Yellow River originates on the Tibetan Plateau and transports vast amounts of terrestrial sediment to the ocean. However, previous studies have not reached a consensus as to when and how the Yellow River first began to flow into the sea. Here we present Sr-Nd-Pb isotope data and a high-resolution clay mineral record of a 200-m-long sediment core recovered from the modern Yellow River delta. The changes in Sr-Nd-Pb isotopic compositions and clay minerals at 0.71 Ma suggest that a larger proportion of sediment was derived from the Yellow River after this time. We propose that the Yellow River has influenced the Bohai Sea since 1.9 Ma (or even earlier), which provides important evidence for an older Yellow River than 1.2 Ma. A significant increase in discharge of Yellow River sediments since 0.71 Ma is due to continuing subsidence of the eastern China coast, the large amplitude of Quaternary sea-level changes, and increased supply of eroded loess during the last 1.0 Ma. After this time, the contribution of local rivers surrounding the Bohai Sea became negligible due to dilution by the huge amounts of Yellow River sediments. These results provide improved constraints on the evolution of the Yellow River and subsequent land-sea fluxes.
Backward stochastic differential equations and Feynman-Kac formula for Levy processes, with applications in finance

In this paper we show the existence and uniqueness of a solution for backward stochastic differential equations driven by a Levy process with moments of all orders. The results are important from a pure mathematical point of view as well as in the world of finance: an application to Clark-Ocone and Feynman-Kac formulas for Levy processes is presented. Moreover, the Feynman-Kac formula and the related partial differential integral equation provide an analogue of the famous Black-Scholes partial differential equation and thus can be used for the purpose of option pricing in a Levy market.
OPA1 Dominant Optic Atrophy: Diagnostic Approach in the Pediatric Population

A clinical and genetic study was conducted with pediatric patients and their relatives with optic atrophy 1 (OPA1) mutations to establish whether there is a genotype–phenotype correlation among the variants detected within and between families. Eleven children with a confirmed OPA1 mutation were identified during the study period. The main initial complaint was reduced visual acuity (VA), present in eight patients of the cohort. Eight of eleven patients had a positive family history of optic atrophy. The mean visual acuity at the start of the study was 0.40 and 0.44 LogMAR in the right and left eye, respectively. At the end of the study, the mean visual acuity was unchanged. Optical coherence tomography during the first visit showed a mean retinal nerve fiber layer thickness of 81.6 microns and 80.5 microns in the right and left eye, respectively; a mean ganglion cell layer of 52.5 and 52.4 microns, respectively, and a mean central macular thickness of 229.5 and 233.5 microns, respectively. The most common visual field defect was a centrocecal scotoma, and nine out of eleven patients showed bilateral temporal disc pallor at baseline. Sequencing of OPA1 showed seven different mutations in the eleven patients, one of which, NM_130837. 3: c. 1406_1407del (p.Thr469LysfsTer16), has not been previously reported. Early diagnosis of dominant optic atrophy is crucial, both for avoiding unnecessary consultations and/or treatments and for appropriate genetic counseling.
A Multifunctional Dental Resin Composite with Sr-N-Doped TiO2 and n-HA Fillers for Antibacterial and Mineralization Effects

Dental caries, particularly secondary caries, which is the main contributor to dental repair failure, has been the subject of extensive research due to its biofilm-mediated, sugar-driven, multifactorial, and dynamic characteristics. The clinical utility of restorations is improved by cleaning bacteria nearby and remineralizing marginal crevices. In this study, a novel multifunctional dental resin composite (DRC) composed of Sr-N-co-doped titanium dioxide (Sr-N-TiO2) nanoparticles and nano-hydroxyapatite (n-HA) reinforcing fillers with improved antibacterial and mineralization properties is proposed. The experimental results showed that the anatase-phase Sr-N-TiO2 nanoparticles were synthesized successfully. After this, the curing depth (CD) of the DRC was measured from 4.36 ± 0.18 mm to 5.10 ± 0.19 mm, which met the clinical treatment needs. The maximum antibacterial rate against Streptococcus mutans (S. mutans) was 98.96%, showing significant inhibition effects (p < 0.0001), which was experimentally verified to be derived from reactive oxygen species (ROS). Meanwhile, the resin exhibited excellent self-remineralization behavior in an SBF solution, and the molar ratio of Ca/P was close to that of HA. Moreover, the relative growth rate (RGR) of mouse fibroblast L929 indicated a high biocompatibility, with the cytotoxicity level being 0 or I. Therefore, our research provides a suitable approach for improving the antibacterial and mineralization properties of DRCs.
A possible origin of galactic magnetic fields

Un modele de generation de champs magnetiques interstellaires, qui considere que chaque galaxie ayant un champ magnetique possede une source centrale compacte, qui lors de phases actives produit des jets a grande echelle qui generent un champ magnetique de force comparable a ceux observes, est presente.
Exploring the Potential of Cannabinoid Nanodelivery Systems for CNS Disorders

Cannabinoids have a major therapeutic value in a variety of disorders. The concepts of cannabinoids are difficult to develop, but they can be used and are advantageous for a number of diseases that are not sufficiently managed by existing treatments. Nanoconjugation and encapsulation techniques have been shown to be effective in improving the delivery and the therapeutic effectiveness of drugs that are poorly soluble in water. Because the bioavailability of cannabinoids is low, the challenge is to explore different administration methods to improve their effectiveness. Because cannabinoids cross the blood-brain-barrier (BBB), they modify the negative effects of inflammatory processes on the BBB and may be a key factor in the improvement of BBB function after ischemic disease or other conditions. This review discusses various types of cannabinoid administration, as well as nanotechnologies used to improve the bioavailability of these compounds in CNS diseases.
Mucosal T Lymphocyte Numbers Are Selectively Reduced in Integrin αE (CD103)-Deficient Mice

The mucosal lymphocyte integrin αE(CD103)β7 is thought to be important for intraepithelial lymphocyte (IEL) localization or function. We cloned the murine integrin gene encoding αE, localized it to chromosome 11, and generated integrin αE-deficient mice. In αE−/− mice, intestinal and vaginal IEL numbers were reduced, consistent with the known binding of αEβ7 to E-cadherin expressed on epithelial cells. However, it was surprising that lamina propria T lymphocyte numbers were diminished, as E-cadherin is not expressed in the lamina propria. In contrast, peribronchial, intrapulmonary, Peyer’s patch, and splenic T lymphocyte numbers were not reduced in αE-deficient mice. Thus, αEβ7 was important for generating or maintaining the gut and vaginal T lymphocytes located diffusely within the epithelium or lamina propria but not for generating the gut-associated organized lymphoid tissues. Finally, the impact of αE deficiency upon intestinal IEL numbers was greater at 3–4 wk of life than in younger animals, and affected the TCR αβ+ CD8+ T cells more than the γδ T cells or the TCR αβ+ CD4+CD8− population. These findings suggest that αEβ7 is involved in the expansion/recruitment of TCR αβ+ CD8+ IEL following microbial colonization. Integrin αE-deficient mice will provide an important tool for studying the role of αEβ7 and of αEβ7-expressing mucosal T lymphocytes in vivo.
Benchmarking Redis and HBase NoSQL Databases using Yahoo Cloud Service Benchmarking tool

The Not Structured Query Language (NoSQL) databases have become more relevant to applications developers as the need for scalable and flexible data storage for online applications has increased. Each NoSQL database system provides features that fit particular types of applications. Thus, the developer must carefully select according to the application’s needs. Redis is a key-value NoSQL database that provides fast data access. On the other hand, the Apache HBase database is a column-oriented database that offers scalability and fast data access, is a promising alternative to Redis in some types of applications. In this research paper, the goal is to use the Yahoo Cloud Serving Benchmark (YCSB) to compare the performance of two databases (Redis and HBase). The YCSB platform has been developed to determine the throughput of both databases against different workloads. This paper evaluates these NoSQL databases with six workloads and varying threads.