Miracle-dz/UniFAR-FTUs huggingface dataset:
Identification of Novel and Differentially Expressed MicroRNAs in Goat Enzootic Nasal 1

28 Enzootic nasal adenocarcinoma (ENA), an epithelial tumor induced in goats and sheep by 29 enzootic nasal tumor virus (ENTV), is a chronic, progressive, contact transmitted disease. 30 This study aimed to identify novel and differentially expressed miRNAs in the tumor and 31 para-carcinoma nasal tissues of Nanjiang yellow goats with ENA. Small RNA Illumina 32 high-throughput sequencing was used to construct a goat nasal miRNA library. 33 406 known miRNAs and 29 novel miRNAs were identified. A total of 116 miRNAs were 34 significantly differentially expressed in para-carcinoma nasal tissues and ENA; Target gene 35 prediction and functional analysis revealed that 6176 non-redundancy target genes, 1792 36 significant GO and 97 significant KEGG pathway for 121 miRNAs were predicted. 37
Two highly singular intermittent structures: Rain and turbulence

Rainfall charges soil moisture and river basins among its many roles with respect to the hydrologic cycle. Research aimed at improved understanding and modeling of surface water processes includes attention to rainfall at a variety of space‐time scales. Given the atmospheric environment in which rain events are observed, some similarities between certain rainfall data structures and fluid turbulence can be expected. So the space‐time intermittency and large fluctuations observed in both rain rates and energy dissipation rates have provided an interest among hydrologists in developing physical theories, experiments, and mathematical models. In response to a request for insights into multiplicative cascade models, the main goal of this article is to single out a special mathematical transformation, namely, “size biasing” (or “tilting”), which has proven to be very powerful in the mathematical analysis of multiplicative cascades and which has also been successfully exploited within the context of turbulence from a physical perspective.
Microaneurysm Detection Analysis in Fundus Images

-An eye condition known as diabetic retinopathy can cause vision loss. Non-proliferative diabetic retinopathy is the early stage of the disease. For the health of patients and clinical diagnosis, non-proliferative diabetic retinopathy must be automatically detected. Microaneurysms happen as the first sign of DR. For DR screening, accurate and reliable microaneurysm detection in fundus imaging is crucial. The inspection time is cut down and accuracy is maintained thanks to automatic detection. In order to identify microaneurysms in retinal fundus images, this research analyses various retinal circumstances, methodologies, and algorithms. We looked at many methods, and we found that algorithms work well to find retinal haemorrhage.
Do Laparoscopic Approaches Ensure Oncological Safety and Prognosis for Serosa-Exposed Colon Cancer? A Comparative Study against the Open Approach

Simple Summary This study examined whether laparoscopic surgery increases the risk of cancer recurrence in patients with T4a colon cancer. A total of 315 patients were analyzed, with 148 in the laparoscopic group and 167 in the open surgery group. Recurrence rates, patterns, and times were similar between the groups. While there was a slightly higher rate of peritoneal metastasis in the laparoscopic group, it was not statistically significant. The five-year overall survival (OS) and disease-free survival (DFS) were not significantly different between the two groups. Age and the pathologic N stage were associated with OS, and only the pathologic N stage was a risk factor for DFS. In conclusion, laparoscopic surgery does not compromise oncologic outcomes in T4a colon cancer patients, despite peritoneal seeding being a common type of recurrence. Abstract The adoption of laparoscopic surgery in the management of serosa-exposed colorectal cancer has raised concerns. This study aimed to investigate whether laparoscopic surgery is associated with an increased risk of postoperative recurrence in patients undergoing resection for serosa-exposed colon cancer. A retrospective analysis was conducted on a cohort of 315 patients who underwent curative resection for pathologically confirmed T4a colon cancer without distant metastases at the Asan Medical Center between 2006 and 2015. Patients were categorized according to the surgical approach method: laparoscopic surgery (MIS group) versus open surgery (Open group). Multivariate analysis was employed to identify risk factors associated with overall survival (OS) and disease-free survival (DFS). The MIS group included 148 patients and the Open group had 167 patients. Of the total cohort, 106 patients (33.7%) experienced recurrence during the follow-up period. Rates, patterns, and time to recurrence were not different between groups. The MIS group (55.8%) showed more peritoneal metastasis compared to the Open group (44.4%) among recurrence sites, but it was not significant (p = 0.85). There was no significant difference in the five-year OS (73.5% vs. 78.4% p = 0.374) or DFS (62.0% vs. 64.6%; p = 0.61) between the Open and MIS groups. Age and the pathologic N stage were independently associated with OS, and the pathologic N stage was the only associated risk factor for DFS. The laparoscopic approach for serosa-exposed colon cancer did not compromise the DFS and OS. This study provides evidence that laparoscopic surgery does not compromise oncologic outcomes of patients with T4a colon cancer although peritoneal seeding is the most common type of disease failure of serosa-exposed colon cancer.
Plug&Play Tractable Multimodal Probabilistic Learning

Data from multiple modalities is ubiquitous in many real world applications and learning a generative model over multimodal data has multiple use cases. Given M modalities or views of a data-point in the form of X 1 , X 2 , . , X M , we aim to learn a joint distribution p θ ( X 1 , X 2 , . . . , X M ) that allows for exact inference queries. This is useful as it allows us to sample from a conditional model which allows us to do things like text guided image synthesis and image captioning from the same model itself (with image, text as the modalities). We can also train using missing data, a common issue in problems with multiple modalities. It is known that probabilistic circuits as a generative model allow for tractable evaluation of the above inference queries. We train independent auto-encoders for each modality and train a tractable generative model on the joint latent space which is simply the concatenation of the latent spaces of individual modalities. We show that our method has a better performance, both quantitative and qualitative on MNIST-SVHN, CelebA-Attributes as compared to prior VAE based methods such as MMVAE (Shi et al., 2019) and MVAE (Wu & Goodman, 2018) which cannot compute inference queries and only rely on variational approximations for the same.
A Trafﬁc Mitigation Method for DDoS Defense in Large Autonomous System

Distributed Denial of Service (DDoS) attacks generate enormous trafﬁc by a large number of agents and can easily exhaust the computing and network resources of a victim within a short period. DDoS attack is more difﬁcult to be detected and blocked than other attack method. Therefore, we designed three new methods being able to tolerate the DDoS attack during its detecting and being blocking. With regard to DDoS attacks into Autonomous System (AS), we deploy routers for trafﬁc distribution in connection with Border Router. This structure reduces DDoS attack trafﬁc by protecting not only victims but also network resources. Moreover, in this paper, we also propose a method to reduce trafﬁc in each router.
SIX-DIMENSIONAL ADAPTIVE SIMULATION OF THE VLASOV EQUATIONS USING A HIERARCHICAL

We present an original adaptive scheme using a dynamically refined grid for the simulation of the six-dimensional Vlasov–Poisson equations. The distribution function is represented in a hierarchical basis that retains only the most significant coefficients. This allows considerable savings in terms of computational time and memory usage. The proposed scheme involves the mathematical formalism of multiresolution analysis and computer implementation of adaptive mesh refinement. We apply a finite difference method to approximate the Vlasov–Poisson equations, although other numerical methods could be considered. Numerical experiments are presented for the d-dimensional Vlasov–Poisson equations in the full 2d-dimensional phase space for d = 1, 2, or 3. The six-dimensional case is compared to a Gadget N-body simulation.
HSOA Journal of Physical Medicine, Rehabilitation & Disabilities

Objective: To determine the number of propulsion repetitions necessary to produce positive changes in propulsion biomechanics of new manual wheelchair users with spinal cord injuries. Design: Single subject design. Setting: Community-based research facility. Participants and intervention: Five new manual wheelchair users with a spinal cord injury (3 men, 2 women, aged 39.0±30) participated in a nine-session manual wheelchair training program that aimed to improve propulsion biomechanics through 5,400 propulsion repetitions. Outcome measures: Assessments were performed on a wheelchair dynamometer at seven levels of repetition dosing. Kinematic measurements (i.e., push loop height, push angles, cadence) were taken using video cameras and Microsoft Kinect systems. Kinetic measurements (i.e., peak force, average force, force rate of rise) were taken using a wheelchair dynamometer system. Result: Each of the five participants had improvements in their propulsion biomechanics (e.g., three participants increased their push angle), which occurred in the first levels of repetition dosing (between 1000-2700 repetitions); there were variances in type of change (kinematic or kinetic). Conclusion: Results suggest that proper propulsion biomechanics can be learned with appropriate dosing. The variability among participants in the type of change that occurred at different dosing levels may be due to differences in wheelchair positioning and level of injury. The impact of manual wheelchair users learning efficient propulsion is great, as engagement in daily activities is dependent upon the health of the upper extremities.
First Steps Towards Accelerating the Learning of Using Exoskeletons with Immersive Virtual Reality

—Learning to use a lower-limb wearable exoskeleton for people with spinal cord injury is time-consuming and requires effort from the user and extensive therapists’ time. In this study, we aim at exploiting visual feedback through immersive virtual reality using a head-mounted display to accelerate motor learning for the purpose of using a wearable exoskeleton with minimal supervision
ReviewArticle Experimental Methods for Measuring Optical Rotatory Dispersion: Survey and Outlook

The measurement of optical rotation (OR) and optical rotatory dispersion has been ﬁnding renewed interest for some years, because of advancement in computational meth-ods and in the performance of new experiments. Here, we shortly review the traditional and most-used experimental methods. We deﬁne and discuss the two main types of approaches in measuring OR: the intensity method and the optical null method. We report on some new results obtained by redesigning experiments based on the ﬁrst approach, by adapting nonso-phisticated hardware to current circular dichroism instrumentation. Chirality 23:711–716, 2011.
The seated medicine ball throw as a test of upper body strength in undergraduate students

The purpose of this study is to correlate the usefulness of Seated Medicine ball throw (SMBT) as a reliable alternate test to evaluate upper body strength using grip dynamometer of the both hands in a healthy adult sample of male and female under graduate students of Kerala Agricultural University. Subjects selected for the study consist of 141 undergraduate students of College of Agriculture, Vellayani, Thiruvananthapuram, Kerala, India. The sample consist of 98 female and 41 male students. Seated Medicine Ball Throw is also called the medicine ball chest pass performance was taken from the participants using 3 kg and 2 kg medicine ball for male and female students respectively. Peak grip strength of each hand were taken using Digital Dynamometer in Kg. The total grip strength was calculated by adding the average of best performance of each hand in Kg. In this study there were 141 participants (98 female and 41 male students) for SMBT and grip strength variables. SMBT having mean of 2.217 ± 0.788. The grip strength total (average grip strength) having a mean of 28.607 kg ± 10.573. Pearson product-moment analyses revealed significant correlation between participants seated medicine ball throw (SMBT) performance with grip strength left (r= .737), grip strength right (r= .713) and grip strength total (r= .738). Simple regression analysis also indicated that SMBT emerged as a significant predictor of total grip strength and based on the results β the linear prediction equation was developed. The predictor explained 64.4% of variance in SMBT (Adjusted R Squire = 0.644), which means that model is strong enough and SMBT can be used as an alternate test for upper body strength among the under graduate students.
Simple and flexible mesh parameterization method

We describe a method to compute conformal parameterizations with a natural boundary based on a simple diﬀerentiable expression measuring angles between edges by using complex numbers. The method can be adapted to preserve metric properties or map textures with constrained positions. Some illustrations are shown to assess the eﬃciency of the algorithms
An Examination of Post-Traumatic Stress Symptoms and An Examination of Post-Traumatic Stress Symptoms and Aggression Among Children with a History of Adverse Childhood Aggression Among Children with a History of Adverse Childhood Experiences Experiences

Childhood aggression is associated with many deleterious outcomes and is a common reason for psychiatric referral (Card and Little 2006; Gurnani, Ivanov, and Newcorn 2016). One factor associated with childhood aggression is Adverse Childhood Experiences (ACEs; Felitti et al. 1998). However, existing research remains equivocal on which characteristics of ACEs (e.g., cumulative impact, typology, etc.) are significantly elated to aggression, especially when considering differential effects of ACEs on proactive aggression (PA) and reactive aggression (RA; Dodge and Coie, 1987). Post-traumatic stress symptoms (PTSS) are a common negative sequalae of ACEs and are characterized by disruptions in several cognitive, emotional, and behavioral processes similar to those associated with both RA and PA (e.g., Marsee 2008). As such, the examination of PTSS as an underlying mechanism of influence on the relation between ACEs, PA, and RA is warranted. The present study fills several gaps in the literature by examining ACE characteristics that might be related to PTSS, PA, and RA while also examining direct and indirect effects on the relation between ACEs, PTSS and PA and RA. Results indicated the type of ACE, specifically child maltreatment ACEs (CM-ACEs), was most strongly related to all outcome variables. Therefore, CM-ACEs were included in a path analysis with PTSS, PA, and RA. Results indicated a significant indirect effect for PTSS on the relation between CM-ACEs and RA ( β = .18, p < .01) but not PA. Findings have several implications for future research and clinical practice, especially for children with an extensive history of CM-ACEs.
EXTENSIONS AND LOW DIMENSIONAL COHOMOLOGY THEORY OF LOCALLY

Let A be an abelian locally compact(2) group and G an arbitrary: locally compact group. We shall say that A is a G-module (or a G-kernel) if¡ G operates continuously as a group of automorphisms of A. By an extension of G by the G-module A we shall mean a locally compact group E with a topological isomorphism i of A onto a closed normal subgroup of E and a homomorphism; j of E onto G which induces a topological isomorphism of E/i(A) with G so that the natural operation of G ~ E/i(A) by conjugation on i(A) a¡ . 4 is the given operation of G on ,4. The notion of equivalence for two such extensions of G by a G-kernel A is clear; it is the analogue with the requisite topological restrictions of the notion for finite groups A and G. The familiar notion of the Baer product of two (equivalence classes of) extensions of G by the same G-kernel A may be introduced in this context. Hochschild [10] has discussed this operation in the context of Lie groups and it is clear that the discussion applies without change for locally compact groups. With the Baer product the set of equivalence classes of extensions of G by A becomes an abelian group Ext (G, A). It is the general purpose of this work to try to gain some insight into the global structure of this group of extensions and some of its properties. Many of the theorems are in a sense "finiteness" theorems for these groups. Considered also is the question of endowing the group of extensions with a topology so that it becomes a topological group. It is certainly reasonable to ask if there is any natural way to tell when two extensions of G by A are ' 'close "to one another. Mackey [17] has posed a related question which concerns giving the group of extensions the structure of a Borel group. When the G-kernel A is the circle group T with trivial operation by G, the group of extensions of G by T is intimately connected with the theory of projective representations of G [19]. The global
Molecular identification of Methicillin-resistant staphylococcus aureus (MRSA) and Vancomycin- resistant staphylococcus aureus (VRSA) strains isolated from milk and milk products.

Keywords In developing countries, resistance to antimicrobial agents is a serious public health problem, and the indiscriminate use of antimicrobials is a key contributor to the development of resistant bacterial diseases. The following research was aimed to determine the in-vitro antimicrobial activity of (23 strains) of Staphylococcus aureus isolated from 80 random samples of milk and dairy products (soft cheese “Kareish and white” and Roomy cheese) 20 samples from each product, with molecular identification of their resistant genes. The results declared that all isolated strains were totally resistant to Ampicillin (100%), Amoxicillin, and Erythromycin (86.9%), then Oxacillin (65.2%), while all other strains showed intermediate susceptibility to Vancomycin, Cefoxitin, Cefotaxime, and Norfloxacin. While Gentamicin had the highest level of susceptibility (78.3%). Moreover, by the cultivation of the isolated strains on oxacillin resistance screening agar base plates “ORSAB,” there were 15/23 MRSA strains; also, 5/23 strains showed resistance to Vancomycin and grow well in vancomycin screening agar. The molecular identification for the mecA gene and vanA gene was made on seven strains (3 strains resistant to both Oxacillin and Vancomycin, two strains with intermediate resistance, and two strains sensitive to them) isolated from different products (milk, Kariesh cheese, soft white cheese, and Roomy cheese). The results showed that all the samples carried the mecA gene, while only two samples had the vanA gene (isolated from milk). Staphylococcus aureus Antimicrobial resistant mecA gene vanA gene
The influence of high‐latitude flux lobes on the Holocene paleomagnetic record of IODP Site U1305 and the northern North Atlantic

Paleomagnetic analysis and radiocarbon dating of an expanded Holocene deep‐sea sediment sequence recovered by Integrated Ocean Drilling Program (IODP) Expedition 303 from Labrador Sea Site U1305 (Lat.: 57°28.5 N, Long.: 48°31.8 W, water depth 3459 m) provides insights into mechanisms that drive both paleomagnetic secular variation (PSV) and magnetization acquisition in deep‐sea sediments. Seventeen radiocarbon dates on planktonic foraminifera define postglacial (ca. 8 ka) sedimentation rates as ranging from 35 to > 90 cm/kyr. Alternating field (AF) demagnetization of u‐channel samples show that these homogeneous sediments preserve a strong, stable, and consistently well‐defined component magnetization. Normalized remanence records pass reliability criteria for relative paleointensity (RPI) estimates. Assuming that the age of magnetization is most accurately defined by well dated PSV records with the highest sedimentation rates, allows us to estimate and correct for temporal offsets at Site U1305 interpreted to result from postdepositional remanence acquisition at a depth of ∼20 cm. Comparisons indicate that the northern North Atlantic PSV and RPI records are more consistent with European than North American records, and the evolution of virtual geomagnetic poles (VGP) are temporally and longitudinally similar to global reconstructions, though with much larger latitudinal variation. The largest deviations from a geocentric axial dipole (GAD) are observed during times of the highest intensities, in contrast to the usual assumption. These observations are consistent with the idea that PSV in the North Atlantic and elsewhere during the Holocene results from temporal oscillations of high‐latitude flux concentrations at a few recurrent locations.
The Effect of Storage Periods on the Quality Characteristics, Fatty Acid Profile and Protein Patterns of Table Eggs

The present study was carried out to detect the effect of different storage temperature and duration on the chemical, physical and functional properties of table eggs. Eggs characterization and proximate analysis showed that the moisture content of fresh whole egg, egg white and egg yolk was found to be 72.95, 87.69 and 49.65 %, respectively. The protein content of the whole egg, white and yolk was 49.17, 93.12 and 33.21 % (on a dry weight basis). Egg-yolk and whole egg were found to contain a fat content of 59.46 and 41.96%, respectively, while egg white was almost free of fat being 0.16%. The ash content of whole eggs, white and yolk was 5.06, 5.12 and 2.38%, respectively. The weight of fresh eggs was 45.55 ± 2.41 g and decreased to a range of 42.01 g to 38 g after 21 days of storage at incubation temperature. During the storage period at different conditions, a significant reduction (P ≤ 0.05) in the yolk index value was found. The albumin pH of the fresh egg was 6.86 and decreased by storage for 21 days at different conditions. The peroxide value increased from 0.704 to 0.84, 1.02, and 1.31 meq O 2 /kg oil for eggs stored for 21 days at refrigeration, ambient temperature, and incubation, respectively. The results illustrated that the foam capacity of eggs decreased with further storage. However, eggs stored at refrigeration had considerably higher foam capacity than those stored at ambient temperature and incubation at 32 ◦ C. The results indicated that the foam of eggs stored at refrigeration was more stable than that stored at both ambient temperature and in the incubator. Oleic acid was the major fatty acid in fresh eggs accounting for 46% of the total fatty acids, whereas palmitic and linoleic acids represent 24.8 and 15.5% of the total acids. The SDS-PAGE proteins pattern showed five dominant polypeptide components and four minor bands in the egg proteins.
¿Crecer para exportar o exportar para crecer? El caso del Valle del Cauca.

Este documento investiga la validez de la hipotesis de crecimiento economico basado en el incremento de las exportaciones empleando datos anuales para el Valle del Cauca durante el periodo 1960 – 2000. No se encuentra evidencia suficiente para validar la relacion causal que supone la hipotesis de crecimiento economico basado en exportaciones. Se emplea un modelo VAR que incluye la produccion y exportaciones departamentales, y dos variables de control, produccion nacional y tasa de cambio real. Los resultados obtenidos suponen una relacion causal que va de produccion a exportaciones. Las funciones de impulso respuesta estimadas indican que la produccion en el Valle del Cauca genera un impacto positivo en las exportaciones mientras que el hecho contrario no ocurre. Los resultados obtenidos para el Valle del Cauca son consistentes con los obtenidos a nivel nacional.