Miracle-dz/UniFAR-FTUs huggingface dataset:
Association of Endovascular Thrombectomy With Functional Outcome in Patients With Acute Stroke With a Large Ischemic Core

Background and Objectives Endovascular thrombectomy (EVT) is effective for patients with large vessel occlusion (LVO) stroke with smaller volumes of CT perfusion (CTP)-defined ischemic core. However, the benefit of EVT is unclear in those with a core volume >70 mL. We aimed to compare outcomes of EVT and non-EVT patients with an ischemic core volume ≥70 mL, hypothesizing that there would be a benefit from EVT for fair outcome (3-month modified Rankin scale [mRS] 0–3) after stroke. Methods A retrospective analysis of patients enrolled into a multicenter (Australia, China, and Canada) registry (2012–2020) who underwent CTP within 24 hours of stroke onset and had a baseline ischemic core volume ≥70 mL was performed. The primary outcome was the estimation of the association of EVT in patients with core volume ≥70 mL and within 70–100 and ≥100 mL subgroups with fair outcome. Results Of the 3,283 patients in the registry, 299 had CTP core volume ≥70 mL and 269 complete data (135 had core volume between 70 and 100 mL and 134 had core volume ≥100 mL). EVT was performed in 121 (45%) patients. EVT-treated patients were younger (median 69 vs 75 years; p = 0.011), had lower prestroke mRS, and smaller median core volumes (92 [79–116.5] mL vs 105.5 [85.75–138] mL, p = 0.004). EVT-treated patients had higher odds of achieving fair outcome in adjusted analysis (30% vs 13.9% in the non-EVT group; adjusted odds ratio [aOR] 2.1, 95% CI 1–4.2, p = 0.038). The benefit was seen predominantly in those with 70–100 mL core volume (71/135 [52.6%] EVT-treated), with 54.3% in the EVT-treated vs 21% in the non-EVT group achieving a fair outcome (aOR 2.5, 95% CI 1–6.2, p = 0.005). Of those with a core volume ≥100 mL, 50 of the 134 (37.3%) underwent EVT. Proportions of fair outcome were very low in both groups (8.1% vs 8.7%; p = 0.908). Discussion We found a positive association of EVT with the 3-month outcome after stroke in patients with a baseline CTP ischemic core volume 70–100 mL but not in those with core volume ≥100 mL. Randomized data to confirm these findings are required. Classification of Evidence This study provides Class III evidence that EVT is associated with better motor outcomes 3 months after CTP-defined ischemic stroke with a core volume of 70–100 mL.
Earth Resources Observation With The Shuttle Imaging Radar

In order to fully understand the radar signature of different surface features and covers, observations must be acquired with a variety of sensor parameters (i.e., frequency, polarization, and incidence angle). This allows the selection of an appropriate set of sensors parameters which will provide the most information about the surface. The Shuttle Imaging Radar (SIR), which is planned by NASA for a series of flights in the 1984-86 time frame, will have the capability to obtain surface images at two frequencies (L-band and C-band), at multiple polarizations, and all incidence angles from near vertical to near grazing. The SIR will operate in the synthetic aperture imaging mode and provide digital images of the surfaces with a resolution of about 20 meters. As part of the SIR flights, a number of planned large-scale experiments will be conducted in the fields of geologic mapping, vegetation classification, land cover mapping, surface moisture measurements, and ocean surface observation.
Interaction-Transformation Evolutionary Algorithm for Symbolic Regression

The Interaction-Transformation (IT) is a new representation for Symbolic Regression that restricts the search space into simpler, but expressive, function forms. This representation has the advantage of creating a smoother search space unlike the space generated by Expression Trees, the common representation used in Genetic Programming. This paper introduces an Evolutionary Algorithm capable of evolving a population of IT expressions supported only by the mutation operator. The results show that this representation is capable of finding better approximations to real-world data sets when compared to traditional approaches and a state-of-the-art Genetic Programming algorithm.
Mapping waterlogging of soils using digital terrain models

Maps of the potential waterlogging of soils were generated using hypotheses about the effect of topography on the soil water regime inspired by Beven and Kirkby's concept of saturation overland flow. The procedure was validated by comparing the simulated maps with maps derived from a 1: 25 000 soil survey for two contrasting catchments. The value and limitations of the method are discussed in the light of this comparison. The approach proposed here is relevant to modelling the distribution of intensely waterlogged soils, provided the relationship between bedrock and the limit values is established. This approach can be used for several purposes: (1) to distinguish positional waterlogging from other types of waterlogging; (2) to control the quality and consistency of waterlogging maps; and (3) to create soil water regime maps for non-surveyed catchments. Conversely, soil water regime maps can be compared with contributing areas simulated by hydrological distributed models for validation purposes.
Climatic Fluctuations and Forecasting of Streamflow in the Lower Colorado River Basin 1

Abstract: Water‐resource managers need to forecast streamflow in the Lower Colorado River Basin to plan for water‐resource projects and to operate reservoirs for water supply. Statistical forecasts of streamflow based on historical records of streamflow can be useful, but statistical assumptions, such as stationarity of flows, need to be evaluated. This study evaluated the relation between climatic fluctuations and stationarity and developed regression equations to forecast streamflow by using climatic fluctuations as explanatory variables. Climatic fluctuations were represented by the Atlantic Multidecadal Oscillation (AMO), Pacific Decadal Oscillation (PDO), and Southern Oscillation Index (SOI). Historical streamflow within the 25‐ to 30‐year positive or negative phases of AMO or PDO was generally stationary. Monotonic trends in annual mean flows were tested at the 21 sites evaluated in this study; 76% of the sites had no significant trends within phases of AMO and 86% of the sites had no significant trends within phases of PDO. As climatic phases shifted in signs, however, many sites had nonstationary flows; 67% of the sites had significant changes in annual mean flow as AMO shifted in signs. The regression equations developed in this study to forecast streamflow incorporate these shifts in climate and streamflow, thus that source of nonstationarity is accounted for. The R2 value of regression equations that forecast individual years of annual flow for the central part of the study area ranged from 0.28 to 0.49 and averaged 0.39. AMO was the most significant variable, and a combination of indices from both the Atlantic and Pacific Oceans explained much more variation in flows than only the Pacific Ocean indices. The average R2 value for equations with PDO and SOI was 0.15.
Long-term pituitary down-regulation before in vitro fertilization (IVF) for women with endometriosis.

BACKGROUND Women with endometriosis who are treated with in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) have a lower pregnancy rate compared to women with tubal factor infertility. It has been suggested that the administration of gonadotrophin releasing hormone (GnRH) agonists for a few months prior to IVF or ICSI increases the pregnancy rate. OBJECTIVES To determine the effectiveness of administering GnRH agonists for three to six months prior to IVF or ICSI in women with endometriosis. SEARCH STRATEGY We used computer searches of the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, EMBASE, the National Research Register (NRR) and the MDSG Specialised Register of controlled trials. We handsearched proceedings of annual meetings of the American Society for Reproductive Medicine (ASRM) and the European Society for Human Reproduction and Embryology (ESHRE). We reviewed lists of references in original research and review articles. We contacted experts in various countries to identify unpublished trials. SELECTION CRITERIA We included randomised controlled trials using any GnRH agonist prior to IVF or ICSI to treat women with any degree of endometriosis diagnosed by laparoscopy or laparotomy DATA COLLECTION AND ANALYSIS Two independent review authors abstracted data (HNS and JGV). We sent e-mails to investigators to seek additional information. We assessed the validity of each study using the methods suggested in the Cochrane Handbook. The data were checked by the third review author (SD) and any disagreement was resolved by arbitration with the fourth review author (AA). We generated 2 x 2 tables for principal outcome measures. The Peto-modified Mantel-Haenszel technique was used to calculate odds ratios (OR) and assess statistical heterogeneity between studies. MAIN RESULTS Three randomised controlled trials (with 165 women) were included. The live birth rate per woman was significantly higher in women receiving the GnRH agonist compared to the control group (OR 9.19, 95% CI 1.08 to 78.22). However, this was based on one trial reporting "viable pregnancy" only. The clinical pregnancy rate per woman was also significantly higher (three studies: OR 4.28, 95% CI 2.00 to 9.15). The information on miscarriage rates came from two trials with high heterogeneity and, therefore, results of the meta-analysis were doubtful. The included studies provided insufficient data to investigate the effects of administration of GnRH agonists on multiple or ectopic pregnancies, fetal abnormalities or other complications. AUTHORS' CONCLUSIONS The administration of GnRH agonists for a period of three to six months prior to IVF or ICSI in women with endometriosis increases the odds of clinical pregnancy by fourfold. Data regarding adverse effects of this therapy on the mother or fetus are not available at present.
Detección de aves exóticas en parques urbanos del centro de México

Las áreas arboladas urbanas son utilizadas por algunas aves invasoras en su proceso de colonización; la detección temprana de estas especies es una acción necesaria para su vigilancia y control. Utilizamos un muestreo rápido en parques urbanos, que requiere de poco tiempo de planeación y ejecución, como una forma de detección de aves que actualmente aumentan su distribución en México: Streptopelia decaocto (paloma de collar), Myiopsitta monachus (perico monje), Turdus rufopalliatus (mirlo dorso rufo) y Sturnus vulgaris (estornino pinto). Realizamos los muestreos en la mayoría de los parques de las ciudades de León de los Aldama, Guanajuato, Aguascalientes y Santiago de Querétaro. Presentamos los primeros registros de M. monachus, T. rufopalliatus y S. vulgaris para la ciudad de León de los Aldama; así como de M. monachus en la de Guanajuato. Además, en Santiago de Querétaro registramos las cuatro especies buscadas; a T. rufopalliatus en Guanajuato, y a S. vulgaris en Aguascalientes. Analizamos las variables asociadas con la presencia de las especies, así como el establecimiento de las especies en cada ciudad en relación con la proporción de parques en que se presentan. Sugerimos que este método es útil para evaluar la distribución actual de estas especies en México y proveer de conocimiento básico para futuros estudios.
Chitosan-collagen scaffolds can regulate the biological activities of adipose mesenchymal stem cells for tissue engineering

Scaffolds of chitosan and collagen can offer a biological niche for the growth of adipose derived stem cells (ADSC). The objective of this work was to characterize the physico-chemical properties of the scaffolds and the ADSC, as well as their interactions to direct influences of the scaffolds on the behavior of ADSC. The methodology included an enzymatic treatment of fat obtained by liposuction by collagenase, ASDC immunophenotyping, cell growth kinetics, biocompatibility studies of the scaffolds analyzed by the activity of alkaline phosphatase (AP), nitric oxide (NO) determination by the Griess-Saltzman reaction, and images of both optical and scanning electron microscopy of the matrices. The extent of the crosslinking of genipin and glutaraldehyde was evaluated by ninhydrin assays, solubility tests and degradation of the matrices. The results showed that the matrices are biocompatible, exhibit physical and chemical properties needed to house cells in vivo and are strong stimulators of signaling proteins (AP) and other molecules (NO) which are important in tissue healing. Therefore, the matrices provide a biological niche for ADSC adhesion, proliferation and cells activities.
Next gen wavelets down-sampling preserving statistics

We extend the 2nd Gen Discrete Wavelet Transform (DWT) of Swelden to the Next Generations (NG) Digital Wavelet Transform (DWT) preserving the statistical salient features. The lossless NG DWT accomplishes the data compression of "wellness baseline profiles (WBP)" of aging population at homes. For medical monitoring system at home fronts we translate the military experience to dual usage of veterans & civilian alike with the following three requirements: (i) Data Compression: The necessary down sampling reduces the immense amount of data of individual WBP from hours to days and to weeks for primary caretakers in terms of moments, e.g. mean value, variance, etc., without the artifacts caused by FFT arbitrary windowing. (ii) Lossless: our new NG_DWT must preserve the original data sets. (iii) Phase Transition: NG_DWT must capture the critical phase transition of the wellness toward the sickness with simultaneous display of local statistical moments. According to the Nyquist sampling theory, assuming a band-limited wellness physiology, we must sample the WBP at least twice per day since it is changing diurnally and seasonally. Since NG_DWT, like the 2nd Gen, is lossless, we can reconstruct the original time series for the physicians' second looks. This technique of NG_DWT can also help stock market day-traders monitoring the volatility of multiple portfolios without artificial horizon artifacts.
Are tibial angles measured with inertial sensors useful surrogates for frontal plane projection angles measured using 2-dimensional video analysis during single leg squat tasks? A reliability and agreement study in elite football (soccer) players

A B S T R A C T During single leg squats (SLS), tibial angle (TA) quantification using inertial measurement units (IMU) may offer a practical alternative to frontal plane projection angle (FPPA) measurement using 2-dimensional (2D) video analysis. This study determined: (i) the reliability of IMUs and 2D video analysis for TA measurement, and 2D video analysis for FPPA measurement; (ii) the agreement between IMU TA and both 2D video TA and FPPA measurements during single leg squats in elite footballers. 18 players were tested on consecutive days. Absolute TA (ATA) and relative TA (RTA) were measured with IMUs. ATA and FPPA were measured concurrently using 2D video analysis. Within-session reliability for all measurements varied across days (intraclass correlation coefficient (ICC) range=0.27–0.83, standard error of measurement (SEM) range=2.12–6.23°, minimal detectable change (MDC) range=5.87–17.26°). Between-sessions, ATA reliability was good for both systems (ICCs=0.70–0.74, SEMs=1.64–7.53°, MDCs=4.55–7.01°), while IMU RTA and 2D FPPA reliability ranged from poor to good (ICCs=0.39–0.72, SEMs=2.60–5.99°, MDCs=7.20–16.61°). All limits of agreement ex- ceeded a 5° acceptability threshold. Both systems were reliable for between-session ATA, although agreement was poor. IMU RTA and 2D video FPPA reliability was variable. For SLS assessment, IMU derived TAs are not useful surrogates for 2D video FPPA measures in this population.
Journal Pre-proof TBS combined with virtual-reality reconsolidation intervention for methamphetamine use disorder: A pilot study

Text The long-term drug-related episodic memory contributes significantly to cue-induced craving in methamphetamine use disorder (MUD) [1]. Long-term episodic memory could be modified during a process known as reconsolidation initiated by memory retrieval under certain conditions [2]. The dorsolateral prefrontal cortex (dlPFC) is a key node in the neural network controlling memory retrieval and reconsolidation [3,4]. Moreover, both animal studies and brain imaging evidence show that the dlPFC is involved in incentive value computation by its reciprocal connection with the limbic system [4,5]. Reduced activation of the dlPFC in MUD may fail to perform a top-down control over the hyperactive limbic system, driving attention to drug-related cues and losing control over craving reactions [6]. Therefore, the dlPFC appears a promising target for non-invasive brain stimulation, especially within a memory reconsolidation intervention paradigm, to reduce craving in MUD. Preliminary studies of intermittent theta-burst stimulation (iTBS) over dlPFC in MUD have demonstrated the reduction of self-reported cravings after 20 daily sessions of iTBS treatment [7]. In this pilot study, we applied a short clinical protocol based on a memory reconsolidation paradigm. We presented drug-using scenes by virtual reality (VR) to facilitate episodic
Plume and bloom: effect of the Mississippi River diversion on the water quality of Lake Pontchartrain

The opening of the Bonnet Carré spillway to prevent flood threat to New Orleans in April 2008 created a sediment plume in the Lake Pontchartrain. The nutrient rich plume triggered a massive algal bloom in the lake. In this article, we have quantified the spatio-temporal distribution of the plume (suspended solids) and the bloom (chlorophyll-a (chl-a)) in the lake using remotely-sensed data. We processed the Moderate-resolution Imaging Spectroradiometer satellite data for mapping the total suspended solids (TSS) and chl-a concentrations. An existing algorithm was used for estimating TSS whereas a novel slope model was developed to predict the per-pixel chl-a concentration. Both algorithms were successful in capturing the spatio-temporal trend of TSS and chl-a concentrations, respectively. Algal growth was found to be inversely related to TSS concentrations and a time lag of ∼45 days existed between the spillway opening and the appearance of the first algal bloom at an observation location.
Modification of Fatty Acid Composition in Rice Plants by Transformation with a Tobacco Microsomal ω-3 Fatty Acid Desaturase Gene (NtFAD3)

A tobacco microsomal ω-3 fatty acid desaturase gene (NtFAD3) under the control of CaMV35S promoter was introduced into rice plants by the microprojectile-mediated transformation. The transgenic plants grew normally and showed high seed fertility and characteristics similar to those of non-transgenic plants. However, the fatty acid compositions in leaves, roots and seeds were modified by the transformation. The content of linoleic acid (18:2) was lower in the transgenic plants than in the non-transgenic plants. However, the content of linolenic acid (18:3) in the root and leaf tissues was, respectively, 1.8- and 1.1-fold higher in 4 transgenic plant lines of the homozygous R3 progenies, than in the non-transgenic plants. The 18:3 content in phosphatidylcholine (PC) and phosphatidylethanolamine (PE) that are the components of the extrachloroplast membrane, in the leaves of mature plants was higher in transgenic plants than in the non-transgenic plants. Thus, NtFAD3 was expressed and it desaturated 18:2 to 18:3 in the endoplasmic reticulum in rice cells.
The determinants of thermal comfort in cool water

Water‐based activities may result in the loss of thermal comfort (TC). We hypothesized that in cooling water, the hands and feet would be responsible. Supine immersions were conducted in up to five clothing conditions (exposing various regions), as well as investigations to determine if a “reference” skin temperature (Tsk) distribution in thermoneutral air would help interpret our findings. After 10 min in 34.5 °C water, the temperature was decreased to 19.5 °C over 20 min; eight resting or exercising volunteers reported when they no longer felt comfortable and which region was responsible. TC, rectal temperature, and Tsk were measured. Rather than the extremities, the lower back and chest caused the loss of overall TC. At this point, mean (SD) chest Tsk was 3.3 (1.7) °C lower than the reference temperature (P = 0.005), and 3.8 (1.5) °C lower for the back (P = 0.002). Finger Tsk was 3.1 (2.7) °C higher than the reference temperature (P = 0.037). In cool and cooling water, hands and feet, already adapted to colder air temperatures, will not cause discomfort. Contrarily, more discomfort may arise from the chest and lower back, as these regions cool by more than normal. Thus, Tsk distribution in thermoneutral air may help understand variations in TC responses across the body.
Granular Media: Between Fluid and Solid

Foreword 1. Introduction 2. Interactions at the grain level 3. The granular solid: statics and elasticity 4. The granular solid: plasticity 5. Granular gases 6. The granular liquid 7. Immersed granular media 8. Erosion and sediment transport 9. Geomorphology References Index.
Italian seismic databank allows on‐line access

Users can interactively query, search, and download parametric information, and digital recordings collected by the Italian Telemetered Seismic Network (ITSN) through the Istituto Nazionale Di Geofisica Seismic Network Databank (ISND). The databank is completely menu-driven and easy to use. The ITSN comprises about 80 seismic stations (Figure 1) equipped with several seismometers acting at a critical damping of 70% and characterized by a period of 1 Hz. The seismometers' signals are transmitted over telephone lines or radio relay systems and then demodulated and recorded by an automatic acquisition system developed in cooperation with the U.S. Geological Survey. Digital data are stored on a magnetic disk and then processed through interactive procedures. The automatic selection of the seismic phases is checked daily and eventually corrected by seismic analysts. New data are available to users within a week.