Miracle-dz/UniFAR-FTUs huggingface dataset:
A Case Report of Pacemaker-Induced Cardiomyopathy in a Patient With Post-atrioventricular Node Ablation for Atrial Fibrillation

Pacemaker-induced cardiomyopathy (PICM) is a rare but well-recognised phenomenon in patients requiring right ventricular (RV) pacing. It can be caused by single-chamber or dual-chamber pacemakers. We present a case of a 64-year-old female patient presenting to the pacemaker clinic with worsening shortness of breath and legs swelling. She was found to have atrial fibrillation and underwent atrioventricular node ablation followed by a dual chamber permanent pacemaker (PPM) implantation as part of a ‘pace and ablate’ strategy to treat refractory symptomatic atrial tachycardia, and the patient was entirely dependent on RV pacing. In the immediate two months following PPM implantation, the patient was seen in the clinic and reported shortness of breath that was attributed to interstitial lung disease. However, a month later her symptoms worsened, stimulating a referral for echocardiography, which demonstrated a fall in her left ventricular ejection fraction (LVEF) from 60% to 30% in just four months after the device implantation. The patient was diagnosed with PICM. The patient’s prognostic heart failure treatment was optimised and her device was upgraded to a cardiac resynchronisation (CRT) device with pacing functionality in an attempt to improve biventricular synchrony. The patient’s symptoms have improved significantly since and a repeat echocardiogram 2 months later showed significant improvement in LVEF to 45-50%.
Self-care practice and associated factors among epileptic patients: a cross-sectional study, Ethiopia

Introduction epilepsy results in multidimensional and long term effect on the patients and society. Self-care practice is critical for epileptic patient. So far, the issue of self-care practice still considered as the most important cause of poorly controlled epilepsy. Yet comprehensive epilepsy self-care practice is not recognized, which is not addressed with medical treatment alone has not been studied particular in Ethiopia. The objective was to assess self-care practice and associated factors among epileptic patients on follow up at Jimma Town public hospitals, 2020. Methods institution based cross-sectional study was conducted from April 08 - May 20/2020. Data was collected using structured interviewer administered questionnaire and data extraction checklist. Simple random sampling technique was used to select a total of 297 study participants. Data was entered to EPI data version 3.5. 3 and exported to SPSS version 23.0 for analysis. Variables with p-value < 0.25 on bivariate analysis were candidated for multivariate analyses. Factors with p value < 0.05 on multivariate analyses were considered as statistically significant. Results a total of 297 study participants were included in the study giving a response rate of 99.0%. Of study participants 146(49.2%) of them were had good self-care practice. Residence (AOR= 1.712, 95%CI: 1.034-2.836, P- 0.037), Seizure frequency (AOR = 0.288, 95% CI: 0.091-0.907, P-0.034), felt stigma (AOR=0.565, 95%CI: 0.342-0.935, P- 0.026) and medication adherence (AOR=0.391, 95%CI: 0.240-0.638, P-0.000) were significantly associated with self-management practice. Conclusion this study found that half of the study participants were had poor self-care practice. Residence, felt stigma, increased seizure frequency and not adherence to medication were factors contributed for poor self-care practice. Therefore, intervention strategies focused on contributing factor for poor self-care practice should be considered.
Racial Discrimination Distress and Psychological Well-being: The Moderating Role of Ethnic-Racial Socialization in African American Emerging Adults

Racial discrimination-related stress is assumed to be inherent in the frequency of the experience; consequently, few studies have examined individual differences in its appraisal. The current study addresses this gap by investigating racial discrimination distress, measured as reported appraisal and frequency, to improve the assessment of race-related risk. The interaction effect of racial discrimination distress and ethnic-racial socialization (ERS) on dimensions of psychological well-being for African American emerging adults was examined. Using a sample of 442 African American emerging adults (Mage = 18.66, SD = 1.05, 80% women), path analyses revealed that racial discrimination distress predicted lower self-esteem and higher depressive symptoms. Racial pride and egalitarian messages were protective against the adverse relationship between racial discrimination distress and psychological well-being. The findings support the importance of race-related risk measurement and the role of ERS in models of normative development for African American emerging adults.
Kinetics of Degradation and Size Distribution of Long Chain Polymers

The rate equations for the depolymerization process of linear chain molecules are formulated and a general solution is given. Three special cases are considered: (a) Equal disintegration probability for all linkages independently of their position in the chain. The results confirm and extend the ones previously found from statistical considerations. (b) Preferred breaking at the ends. (c) Equal disintegration probability for all chains independently of their size. Equations for the decrease of number and weight average molecular weight with time are given in each case.
Predicting Statistical Wave Physics in Complex Enclosures: A Stochastic Dyadic Green's Function Approach

This article presents a physics-oriented, mathematically tractable, statistical wave model for analyzing the wave physics of high-frequency reverberation in complex cavity environments. The key ingredient is a vector dyadic stochastic Green's function (SGF) method that is derived from the Wigner's random matrix theory and Berry's random wave hypothesis. The SGF statistically replicates multipath, ray-chaotic communication between vector sources and vectorial electromagnetic fields at displaced observation points using generic, macroscopic parameters of the cavity environment. The work establishes a physics-based modeling and simulation capability that predicts the probabilistic behavior of backdoor coupling to complex electronic enclosures. Experimental results are supplied to validate the proposed work.
Systolic arrays: how to choose them

In this paper, we look closely into the effect of objective function optimisation on the architecture of systolic arrays. Various objective functions such as area, speed, throughput, AT and AT2 have been considered. In each case, when the objective function is optimised, a different systolic array is produced. We present our approach systematically using the space-time techniques of mapping algorithms into systolic arrays.
CH, CO, and E(B–V) as Molecular Gas Tracers in a Translucent Cloud

The effectiveness of three molecular hydrogen gas tracers—the CH 2Π1/2, J = 1/2, F = 1-1 transition, the CO(1-0) transition, and the color excess, E(B-V)—is evaluated for the translucent molecular cloud MBM 16. The CH emission line and E(B-V) are well correlated with each other but not with the CO(1-0) emission line. It is likely that in translucent molecular clouds CO is not a linear tracer of the molecular hydrogen column density because, in these objects, the CO/H2 ratio is undergoing rapid fluctuations as a function of the molecular hydrogen column density. For translucent and diffuse molecular clouds, and possibly for the translucent envelopes of giant molecular clouds, CH observations should be used to calibrate the CO to H2 conversion factor.
Sporadic mass loss, spin-down, and element redistribution in young disk galaxies

Violent conditions in young spiral disks may be conducive to the high-velocity ejection of large blobs of material powered by the concerted action of supernovae. Using explicit numerical Monte Carlo models, treating ejected bobs as galactic cannonballs traveling with little interaction through the corona, several important consequences for galactic evolution are found. Preferential escape from the galaxy or objects with high specific angular momenta lead to a significant spin-down of the disk. In addition, this process may contribute to the production of an exponential column density distribution, and a metallicity gradient. The models predict a reversal in the sign of the metallicity gradient at large radii because the metal-rich objects that return to such a low column density region suffer relatively little dilution. 39 refs.
Directional adhesion behavior of a single elastic fiber

Theoretical analysis and optimum design of directional adhesion property are of great importance for developing high performance biomimetic fibrillar adhesives. In this paper, a theoretical study is made on the deformation and adhesion behavior of a single straight fiber contacting with a rigid smooth surface under the coupling effect of normal and shear forces. The influences of the fiber’s bending stiffness and slanted angle on the adhesion behavior are studied. It has been found that the coupling effect of normal and shear forces leads to directional adhesion behavior. Moreover, the detachment mode and the enhancement of the normal pull-off force with the increase of the applied shear force could be directly predicted based on the derived formulas. The stability of adhesion equilibrium states has also been determined by using the stability criterion of energy minimization. These theoretical findings are in good agreement with recent experiments qualitatively, and they are expected to be valuable for op.
Asymptotic distribution of the reduced rank regression estimator under general conditions

In the regression model Y = η + BX + Z with Z unobserved, EZ = 0 and EZZ' = Σ ZZ , the least squares estimator of B is B = S YX S -1 XX . If the rank of B is known to be k less than the dimensions of Y and X, the reduced rank regression estimator of B, say B k , depends on the first k canonical variates of Y and X. The asymptotic distribution of B k is obtained and compared with the asymptotic distribution of B. The advantage of B k is characterized.
Equipment Maintenance Effect on Energy Losses Reduction at Medium Voltage Distribution Network

The energy loss is one of primary problems at medium voltage distribution network. The declining quality of distribution network equipment is main factor of energy losses. The equipment maintenance has a significant correlation with energy losses reduction. This research discussed the effect of equipment maintenance on energy losses reduction at medium voltage distribution network. The research object was a feeder of 20 kV medium voltage overhead line at Bontoala Substation, Makassar. The research method was the quantitative calculation of energy losses in a month based on empirical formulas, with and without maintenance condition. The calculation was performed on three distribution network equipment: connector, transformer, and insulators. Based on the calculation results, the total energy losses without maintenance were 118,373.429 kWh. With maintenance, the value of losses can be reduced to 36,960.339 kWh or equal with 68.776% reduction. The research result shows the significant impact on equipment maintenance to distribution network energy losses.
Reassessment of the Volumes of Sediment Sources and Sinks on Venus

The dominant source of sediment on Venus is thought to be impact cratering, wherein crater ejecta is redistributed across the planet by winds. Here we provide a refined global sediment budget for Venus by mapping and quantifying the volume of sediment from impact craters observable in Magellan data using updated methodology. We improve on previous estimates of the volume of impact-generated sediment by mapping the impact deposits for all craters ≥11 km on Venus. We estimate the planet’s total budget of impact sediment to be a minimum of 290,000 km3, which corresponds to a global layer of sediment 63 cm thick. If erosional processes have been active over the average surface age (500 Ma–1 Ga), the transportable fraction of this volume implies a sediment mobilization rate between 0.18 and 0.36 nm yr−1, comparable to the late Hesperian–Amazonian era of Mars. We requantify the volume of sediment held in recognized eolian features by (1) applying morphometric studies of planetary analogs to assess the volumes of observed Venusian dune and yardang fields and (2) estimating the volume of proposed microdune fields. We also identify a new yardang field near Mead crater. Globally, we find that >100,000 km3 of available sediment is not accounted for by eolian deposits, concurring that lithification, resurfacing, and fields of as yet unidentified eolian features are other potential sinks for sediment. However, locally, individual eolian fields contain more sediment than can be derived from nearby craters, indicating that these fields contain additional sediment from other sources.
M5 brane on R 1 , 2 × S 3

: We deconstruct 16 rigid supersymmetry variations for M5 brane on R 1 , 2 × ( S 3 / Z k ) and obtain on-shell closure on Lie derivatives. Dimensional reduction on the Hopf ﬁber by taking k → ∞ gives sYM on R 1 , 2 × S 2 with 8 rigid supersymmetries. We reproduce the result in arXiv:0908.3263 but we also derive an additional graviphoton term which is associated with the twisting of the Hopf bundle.
Dipole glass and ferroelectricity in random-site electric dipole systems

Dipole glasses are formed when dielectrics are doped with off-center ions and are often considered as the electronic analogs of spin glasses. However, the analogy is only partial, and, in particular, when the host crystal is highly polarized, there are new effects that are explained as arising from macroscopic regions of spontaneous polarization induced at certain concentrations of the off-center ions
The Lupus Epigenome Relates to Genetics, Transcription and Serological Profiles with Dependency on Molecular Subtypes and Informs Drug Discovery

Objective. The heterogeneity of systemic lupus erythematosus (SLE) can be explained by epigenetic alterations that disrupt transcriptional programs mediating environmental and genetic risk. This study evaluated the epigenetic contribution to SLE heterogeneity considering molecular and serological subtypes, genetics and transcriptional status, followed by drug target discovery. Methods. We performed a stratified epigenome-wide association studies of whole blood DNA methylation from 213 SLE patients and 221 controls. Methylation quantitative trait loci analyses, cytokine and transcription factor activity - epigenetic associations and methylation-expression correlations were conducted. New drug targets were searched for based on differentially methylated genes. Results. In a stratified approach, a total of 974 differential methylation CpG sites with dependency on molecular subtypes and autoantibody profiles were found. Mediation analyses suggested that SLE-associated SNPs in the HLA region exert their risk through DNA methylation changes. Novel genetic variants regulating DNAm in disease or in specific molecular contexts were identified. The epigenetic landscapes showed strong association with transcription factor activity and cytokine levels, conditioned by the molecular context. Epigenetic signals were enriched in known and novel potential drug targets for SLE. Conclusion. This study expands the number of genes associated with SLE and reveals novel pathways of disease. The findings reveal possible genetic drivers and consequences of epigenetic variability on SLE heterogeneity and disentangles the DNAm mediation role on SLE genetic risk and the genetic architecture of DNAm in different molecular contexts. Finally, novel targets for drug development were discovered.
Small angle neutron scattering and calorimetric studies of large unilamellar vesicles of the phospholipid dipalmitoylphosphatidylcholine

High-resolution differential scanning calorimetry (DSC) and small angle neutron scattering (SANS) experiments have been conducted on large unilamellar vesicles (LUV{close_quote}s) of the phospholipid dipalmitoylphosphatidylcholine (DPPC) in excess water. The DSC results indicate a phase transition at temperatures corresponding to the gel (L{sub {beta}{sup {prime}}}) to ripple (P{sub {beta}{sup {prime}}}) phase transition seen in multilamellar vesicles of DPPC while the SANS experiments provide direct evidence for the formation of the P{sub {beta}{sup {prime}}} phase in these systems. In addition, it is shown that SANS is an effective technique for extracting structural parameters such as vesicle radius and thickness in LUV model membrane systems. {copyright} {ital 1999} {ital The American Physical Society}
THE ASTRONOMY OF X‐RAY SOURCES AND THE PHYSICS OF ACCRETION *

The understanding of x-ray stars is, a t present, similar to the level of comprehension of optical stars in the second and third decades of this century. At that time there was, on the astronomical side, only the first primitive classification into sources of different types; and from the physical side there was a hint that A E = AMc’ was relevant in understanding the problem of energy generation and that, provided an energy source could be found, one could calculate, to lowest order, the equilibrium achievable for stars of stellar mass and radius between the forces of gravity and thermal pressure. Today, we can roughly classify stellar x-ray sources into a few types, x-rayemitting radio pulsars, I M, companions of Pop. I binary stars, normal stellar coronae, etc. However, most of the sources detected thus far have not in any sense been classified. For example, the majority of the bright galactic center sources or bright Maggellenic Cloud sources isolated by Margon and Ostriker’ are of a totally unknown type. All we can say at present is that they are probably not like any of the well-studied relatively nearby sources Cen X-3, NP0532 (the Crab pulsar), or (probably) Sco X1. Our physical understanding is similarly at a primitive level. I t is generally believed that most high-luminosity kilovolt sources (thereby excluding normal coronae, and accreting degenerate dwarfs) derive their energy from gravitational energy released by matter accreting onto a compact object, either a neutron star or a black hole, with the observable x-rays being emitted from a region near the compact object-surface, surrounding disk, magnetosphere, etc. But beyond that, our models become very approximate. I n this talk I would like to make some small, but I hope real, contributions to both aspects of the problem: to pursue the phenomenology of x-ray sources pointing to similarities of properties within certain subgroups of the “unclassified” sources, and to remark on the instabilities inherent in all of the suggested physical mechanisms of accretion, which implies to me that unsteadiness of emission should be the rule, rather than the exception among x-ray sources.
Design of single-mode step-tapered waveguide sections

Single-mode step-tapered waveguide sections are analyzed in an effort to determine how the various device parameters, specifically, taper function, mask spot size, and taper length, affect power loss. The results indicate that 1) for short to medium length tapers, linear tapers exhibit the lowest loss, whereas for long tapers, all of the taper functions exhibit essentially the same loss; 2) for single-mode transitions with waveguide widths in the range 2-15 \mu m, the loss in a step-tapered waveguide section can be nearly minimized as long as the mask spot size is chosen such that there are at least 20-25 steps in the taper; and 3) the length of a given taper for minimum power loss is strongly influenced by the asymmetry of the waveguide structure.
On Information Structures, Feedback and Causality

A finite number of decisions, indexed by $\alpha \in A$, are to be taken. Each decision amounts to selecting a point in a measurable space $(U_\alpha ,\mathcal{F}_\alpha )$. Each decision is based on some information fed back from the system and characterized by a subfield $\mathcal{J}_\alpha $ of the product space $(\prod _\alpha U_\alpha ,\prod _\alpha \mathcal{F}_\alpha )$. The decision function for each $\alpha $ can be any function $\gamma _\alpha $ measurable from $\mathcal{J}_\alpha $ to $\mathcal{F}_\alpha $. A property of the $\{ \mathcal{J}_\alpha \} _{\alpha \in A} $ is defined which assures that the setup has a causal interpretation. This property implies that for any combination of choices of the $\gamma _\alpha $, the closed loop equations have a unique solution.The converse implication is false, when card $A > 2$.
Reproducible resistance switching in polycrystalline NiO films

Negative resistance behavior and reproducible resistance switching were found in polycrystalline NiO films deposited by dc magnetron reactive sputtering methods. Oxygen to argon gas ratio during deposition was critical in deciding the detailed switching characteristics of either bi-stable memory switching or mono-stable threshold switching. Both metallic nickel defects and nickel vacancies influenced the negative resistance and the switching characteristics. We obtained a distribution of low resistance values which were dependent on the compliance current of high-to-low resistance switching. At 200°C, the low-resistance state kept its initial resistance value while the high-resistance state reached 85% of its initial resistance value after 5×105s. We suggested that the negative resistance and the switching mechanism could be described by electron conduction related to metallic nickel defect states existing in deep levels and by small-polaron hole hopping conduction.
The Local and Systemic Exposure to Oxygen in Children With Severe Bronchiolitis on Invasive Mechanical Ventilation: A Retrospective Cohort Study

OBJECTIVES: Oxygen supplementation is a cornerstone treatment in critically ill children with bronchiolitis in the PICU. However, potential deleterious effects of high-dose oxygen are well-known. In this study, we aim to describe the pulmonary (local) and arterial (systemic) oxygen exposure over the duration of invasive mechanical ventilation (IMV) in children with severe bronchiolitis. Our secondary aim was to estimate potentially avoidable exposure to high-dose oxygen in these patients. DESIGN: Retrospective cohort study. SETTING: Single-center, tertiary-care PICU. PATIENTS: Children younger than 2 years old admitted to the PICU for severe bronchiolitis receiving IMV. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: Hourly measurements of Fio2 and peripheral oxygen saturation (Spo2), and arterial blood gas data were collected up to day 10 of IMV. A total of 24,451 hours of IMV were observed in 176 patients (median age of 1.0 mo [interquartile range (IQR), 1.0–2.3 mo]). The pulmonary exposure to oxygen was highest during the first day of IMV (median time-weighted average [TWA]–Fio2 0.46 [IQR, 0.39–0.53]), which significantly decreased over subsequent days. The systemic exposure to oxygen was relatively low, as severe hyperoxemia (TWA–Pao2 > 248 Torr [> 33 kPa]) was not observed. However, overuse of oxygen was common with 52.3% of patients (n = 92) having at least 1 day of possible excessive oxygen exposure and 14.8% (n = 26) with severe exposure. Furthermore, higher oxygen dosages correlated with increasing overuse of oxygen (rrepeated measures, 0.59; 95% CI, 0.54–0.63). Additionally, caregivers were likely to keep Fio2 greater than or equal to 0.50 when Spo2 greater than or equal to 97%. CONCLUSIONS: Moderate to high-dose pulmonary oxygen exposure and potential overuse of oxygen were common in this cohort of severe bronchiolitis patients requiring IMV; however, this was not accompanied by a high systemic oxygen burden. Further studies are needed to determine optimal oxygenation targets to prevent overzealous use of oxygen in this vulnerable population.