Miracle-dz/UniFAR-FTUs huggingface dataset:
Efficiency Improvement of Radial Flux Permanent Magnet Brushless DC Motor Using Hiperco Magnetic Material

Performance enhancement of permanent magnet brushless dc motor during design is highly desirable. With the application of superior magnetic material Hiperco in place of traditional magnetic material M19 silicon steel, the performance of the permanent magnet brushless dc motor (PMBLDC) can be greatly improved. Compared to standard silicon steel material the Hiperco magnetic material has high allowable flux density, high permeability and low specific iron loss. This paper presents the use of Hiperco magnetic material for the stator core of PMBLDC motor. The 200 W, 24 V radial flux PMBLDC motor is designed analytically and modelled in finite element analysis (FEA) software. The initial design incorporates use of M19 – 29 Ga Cold Rolled Non Oriented (CRNO) silicon steel material for the stator core. The initial design is validated using finite element analysis. In improved design, the conventional stator core material is replaced by Hiperco magnetic material and effect of Hiperco on the efficiency of the PMBLDC motor is analyzed. The improved model with the application of Hiperco is analyzed with FEA technique. It is analyzed that efficiency of PMBLDC motor is considerably improved with application of Hiperco.
Active Frequency Selective Surface Absorber With Point-to-Point Biasing Control System

A frequency selective surface (FSS) absorber with a biasing control system is presented in this letter. The absorber consists of the top-layer FSS structure, the bottom-layer metal sheet, and an air spacer in between. The biasing circuit is controlled by a single-chip microcomputer with constant current outputs and each output port is connected to one p-i-n diode, which is employed to realize different absorption bands by controlling the induced current distribution. Both simulated and measured results demonstrate that fast switching function can be realized within certain frequency ranges (3.62–5.35 GHz and 7.92–9.27 GHz) with the absorption depth below −10 dB.
Time-lapse electromagnetic and gravity methods in carbon storage monitoring

For geologic carbon storage (GCS), monitoring of the storage reservoir and detection of secondary plumes if they accumulate outside of the reservoir are important to confirm that the injected CO2 stays where intended. Seismic methods are most often applied but are expensive. Due to cost considerations, especially for long-term monitoring, less expensive techniques play a role when designing monitoring networks. In this article, the merits of gravity and electromagnetic (EM) methods as monitoring tools for GCS are presented. Many of the technologies are well established, and several new technologies are on the horizon. EM and gravity techniques are complementary to seismic methods and together provide better subsurface monitoring. Time-lapse multiphysics joint inversion, including seismic, EM, and gravity, could be a game changer for carbon storage monitoring. The trade-off between the sensitivity or resolution to a given plume size and the associated costs will be an important factor in selecting efficient and reliable monitoring arrays at GCS sites. Complex digital models representing geology encountered at storage sites can be used for this purpose and present another cost savings.
Hidden Fluids in Plain Sight: Identifying Intravenous Medication Classes as Contributors to Intensive Care Unit Fluid Intake

Introduction: Fluid stewardship targets optimal fluid management to improve patient outcomes. Intravenous (IV) medications, flushes, and blood products, collectively referred to as hidden fluids, contribute to fluid intake in the intensive care unit (ICU). The impact of specific IV medications on fluid intake is unknown. Objective: Characterize IV medication classes based on contribution to ICU fluid intake by frequency of administration and total volume infused to identify targets for fluid stewardship. Methods: This multi-center, retrospective nested cohort study included patients admitted to a medical or surgical ICU between January 2017 and December 2018. The primary outcome was to identify the volume contribution of specific IV medication classes administered over the first 3 ICU days. Secondary outcomes were the administration frequency of these medications and their proportion of total daily volume intake over the first 3 ICU days. Results: The study included 210 patients. The largest mean administration volumes over the course of the first 3 ICU days were attributed to antibacterials (968 ± 846 mL), vitamins/minerals/electrolytes (416 ± 935 mL), pain/agitation/delirium agents (310 ± 512 mL), and vasoactive agents (282 ± 744 mL). The highest frequencies over the course of the first 3 ICU days were attributed to antibacterials (n = 180; 86%), pain/agitation/delirium agents (n = 143; 68%), vitamins/minerals/electrolytes (n = 123; 59%), and vasoactive agents (n = 96; 46%). IV medications contributed 2601 ± 2573 mL of fluid volume per patient over the first 3 ICU days, accounting for 42% ± 29% of overall volume. Conclusion: IV medications contribute over 40% of total fluid intake within the first 3 days of ICU admission, with antibacterials as top contributors by administration volume and frequency. Future research implementing fluid stewardship to ICU fluid sources, such as concentrating IV medications, switching IV medications to oral formulations, de-escalation of antibacterials, and reduction of maintenance fluids, should be performed to minimize hidden fluids from IV medications.
Neolignans and Phenylpropanoids from the Rhizomes of Coptis japonica var. dissecta

Six new dihydrobenzofuran neolignans were isolated from the fresh rhizomes of Coptis japonica var. dissecta, together with (+)-isolariciresinol, (+)-lariciresinol glucoside, (+)-pinoresinol, (+)-pinoresinol glucoside, (+)-syringaresinol glucoside and ethyl ferulate. Their structures were determined on the basis of spectroscopic data and chemical evidence. Their absolute configurations were determined by means of CD studies.
Management of Posidonia Oceanica Leaf Litter in Calabrian Sandy Beaches (Southern Italy).

The wracks of Posidonia oceanica leaves on the sandy beaches of Calabrian region could be one of the most important defence against erosion processes. The management of Posidonia oceanica leaf litter in Italy has been realized through the mechanical removal and the transport in dumping areas of the beach-cast material. This solution, apparently simple and fast, produces a net loss of sediments from the sandy beaches and, therefore, a deficit in the sedimentary budget of coastline leading the coastal system to possible shore erosions. Instead, it could be better to keep these vegetable deposits on the place so to warrant a positive sedimentary budget and the tourist value of the regional beaches improving coastal tourism in the seaside resorts with bathing vocation.
Unlocking loxP to Track Genome Editing In Vivo

The development of CRISPR-associated proteins, such as Cas9, has led to increased accessibility and ease of use in genome editing. However, additional tools are needed to quantify and identify successful genome editing events in living animals. We developed a method to rapidly quantify and monitor gene editing activity non-invasively in living animals that also facilitates confocal microscopy and nucleotide level analyses. Here we report a new CRISPR “fingerprinting” approach to activating luciferase and fluorescent proteins in mice as a function of gene editing. This system is based on experience with our prior cre recombinase (cre)-detector system and is designed for Cas editors able to target loxP including gRNAs for SaCas9 and ErCas12a. These CRISPRs cut specifically within loxP, an approach that is a departure from previous gene editing in vivo activity detection techniques that targeted adjacent stop sequences. In this sensor paradigm, CRISPR activity was monitored non-invasively in living cre reporter mice (FVB.129S6(B6)-Gt(ROSA)26Sortm1(Luc)Kael/J and Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/J, which will be referred to as LSL-luciferase and mT/mG throughout the paper) after intramuscular or intravenous hydrodynamic plasmid injections, demonstrating utility in two diverse organ systems. The same genome-editing event was examined at the cellular level in specific tissues by confocal microscopy to determine the identity and frequency of successfully genome-edited cells. Further, SaCas9 induced targeted editing at efficiencies that were comparable to cre, demonstrating high effective delivery and activity in a whole animal. This work establishes genome editing tools and models to track CRISPR editing in vivo non-invasively and to fingerprint the identity of targeted cells. This approach also enables similar utility for any of the thousands of previously generated loxP animal models.
Use of the pK Spectroscopy Method in the Study of Protolytic Properties of Humic Substances and Other Soil Polyelectrolytes

A common technique for the potentiometric analysis of complex protolytic systems is mathematical data processing. This approach allows for transforming the experimental titration curve into a function of the ionogenic group distribution of the titrated object by the values of the pK (−lgKa) acid dissociation. This distribution function is called the pK spectrum, and the approach itself is called pK spectroscopy. In this case, solutions are found not in the form of discrete dissociation constants but as a distribution function of the concentrations of ionogenic groups over a continuous spectrum of dissociation constants. The purpose of this work is to test the possibility of using the pK spectroscopy method for assessing the acid–base properties of humic substances, water-soluble fraction, and soils. The results of testing the pK spectroscopy method showed that this method is expressive and more informative than the traditional method of continuous potentiometric titration. The use of the pK spectroscopy method for studying the protolytic properties of humic substances and other environmental objects is justified. The content and values of pK of ionogenic groups of fulvic acids, water-soluble fraction, and soil suspensions were determined. In the objects, the presence of three to five ionogenic groups with pK values from 3.2 to 9.6 was revealed.
Selective Deoxygenation of Aldehydes: The Reaction of Acetaldehyde and Glycolaldehyde on Zn/Pt(111) Bimetallic Surfaces

Temperature programmed desorption (TPD) and high resolution electron energy loss spectroscopy (HREELS) were used to characterize the adsorption and reaction of acetaldehyde and glycolaldehyde on Zn-modified Pt(111) surfaces. The barriers for both C–H and C–C bond cleavage in adsorbed aldehydes were found to be higher on Pt(111) decorated with Zn adatoms or containing a PtZn near-surface alloy, compared to Zn-free Pt(111). This results in stabilization of aldehydes adsorbed in an η2(C,O) bonding configuration and hinders formation of acyl intermediates as typically occurs on group 10 metals. Adsorbed η2(C,O) acetaldehyde and glycolaldehyde on Zn-modified Pt(111) were found to undergo selective C–O bond scission to produce adsorbed hydrocarbon intermediates and hydroxyl groups, while decarbonylation of acyl species to produce CO and hydrocarbon fragments was the primary pathway on the Zn-free surface. These results provide mechanistic insights that are useful for the design of hydrodeoxygenation catalysts f.
Traits to Differentiate Lineages and Subspecies of Aegilops tauschii, the D Genome Progenitor Species of Bread Wheat

Aegilops tauschii Coss. , the D genome donor of hexaploid wheat (Triticum aestivum L.), is the most promising resource used to broaden the genetic diversity of wheat. Taxonomical studies have classified Ae. tauschii into two subspecies, ssp. tauschii and ssp. strangulata. However, molecular analysis revealed three distantly related lineages, TauL1, TauL2 and TauL3. TauL1 and TauL3 includes the only ssp. tauschii, whereas TauL2 includes both subspecies. This study aimed to clarify the phylogeny of Ae. tauschii and to find the traits that can differentiate between TauL1, TauL2 and TauL3, or between ssp. tauschii and ssp. strangulata. We studied the genetic and morpho-physiological diversity in 293 accessions of Ae. tauschii, covering the entire range of the species. A total of 5880 high-quality SNPs derived from DArTseq were used for phylogenetic cluster analyses. As a result, we observed wide morpho-physiological variation in each lineage and subspecies. Despite this variation, no key traits can discriminate lineages or subspecies though some traits were significantly different. Of 124 accessions previously lacking the passport data, 66 were allocated to TauL1, 57 to TauL2, and one to TauL3.
Influence measures and outliers detection in linear mixed measurement error models with Ridge estimation

Abstract In this article, we have concentrated on the influence diagnostics based on the mean shift outlier models (MSOM) and case deletion methods in the linear mixed measurement error models with Ridge estimation using the corrected likelihood of Nakamura (1990). We have derived the corrected score test statistic for outliers detection according to MSOM. Then, several case deletion measures are constructed as a tool for influence diagnostics. A parametric bootstrap procedure is used to obtain empirical distributions of the test statistics, and a simulation study has been used to show the performance of the proposed score test statistic and cook distance. Finally, a numerical example is given to illustrate the theoretical results.
Effect of "Motivational Interviewing" And "Information, Motivation and Behavioral Skills” On Choosing Mode of Delivery In Pregnant Women: A Randomized Controlled Trial

Background: Cesarean section is an important surgical procedure to save mothers and/or babies’ lives. Current trends show that the rate of Cesarean section is increasing dramatically over the years. The aims of this study were to compare the effects of "motivational interviewing" and "information, motivation and behavioral skills” model on choosing mode of delivery among pregnant women.Methods: In a four-armed, parallel-design randomized controlled trial, 120 women were randomly assigned to three brief interventions and one control groups. We recruited pregnant women referring to Ebnesina hospital, Tehran- Iran from 2019-2020. The intervention groups included: 1) motivational interviewing; 2) face-to-face information, motivation and behavioural skills model; and 3) information, motivation and behavioural skills model provided using a mobile application. The control group received usual antenatal care. The inclusion criteria were being literate, gestational age 24 to 32 weeks at recruitment, being able to speak Persian, having no complications in the current pregnancy, having no indications for CS, and having enough time to participate in the intervention sessions. The primary outcome of the study was mode of delivery. The secondary outcomes included women’s intentions to undergo any mode of delivery and women’s self-efficacy in choosing the mode of delivery. Data were analyzed using descriptive statistics (mean, frequency and standard deviation), inferential statistics including independent t-test, Paired t-test, and analysis of variance (ANOVA). Results: Following the interventions, significant differences were found in the women’s self-efficacy and intention to choose mode of delivery (P < 0.05). Women who had used the mobile application had more improvements in the self-efficacy and intention than the face-to-face intervention groups. Conclusions: Our study showed positive significant effects of various types of brief interventions to improve women’s self-efficacy and intention to choose mode of delivery among the participant women. Providing the intervention using mobile application showed even better results. However, in order to decrease unnecessary CS rate, evidence-based interventions targeted at health-facility and health system levels should be implemented along with these simple, non-expensive, tailored to women, and culture-oriented brief interventions.Trial registration: This study has been registered in Iran Randomized Clinical Trial Center (IRCT20151208025431N7). Registered on (07/12/2018).
Comparative Analysis of Nutritional Quality of Dendrobium Officinale Kimura Et Migo After Transplantation of Artificially Cultivated Plants From South to North China During Different Growing Years

Background: Dendrobium officinale Kimura et Migo is a traditional functional food and medicinal plant in China. Due to low natural regeneration rates, habitat destruction, excessive collection and commercial trade, D. officinale is severely threatened, and commercial artificial-sheltered cultivation has been massively used to meet the needs of the market. Aim: To comprehensively compare the accumulation of nutritional compounds during 3-5 years of introduced, artificial-sheltered cultivation from southern to northern China.Methods: D. officinale of the same species were artificially cultivated in the southern traditional cultivation area, Anhui and the new northern cultivation area, Beijing. First, samples were collected in the third, fourth, and fifth years of growth, and nutritional quality indexes, including polysaccharides, alkaloids, flavonoids and total phenolic content, were determined. Second, an untargeted metabolomics method was used to investigate metabolic variations in D. officinale stems between Anhui and Beijing cultures in the fifth year.Results: After comparing the nutrient accumulation in different growing years, the idea harvest time was found in the third growing year in both cultivation areas. Of them, the contents of polysaccharides, flavonoids and total polyphenol were higher in cultivation in Anhui than Beijing, but the accumulation of alkaloid content was much lower in Anhui. The highest amount of polysaccharides of Dendrobium officinale was found in the three-year cultivation in Anhui, which reached 515.75 mg/g. When metabolites were analysed, a total of 272 metabolites were detected in the current study, including 27 up-regulated and 73 down-regulated metabolites in D. officinale cultivated in Beijing compared with samples from Anhui. Conclusion: D. officinale artificially and transplanted cultivated from southern to northern China showed some significant differences in the accumulation of nutrient compounds. Planting in northern China has some specific advantages, but the overall nutritional value is not as good as planting in southern China. Our study contributes to a better understanding of the nutrient profiles of D. officinale through artificial cultivation in different areas.
Regional Environmental Systems as a Driver of Innovative Economy in Ukraine

Nowadays, the concept of innovative development is a generally accepted approach to promoting social and economic development paradigm both at global and national level. However, the rapid changes in external and internal conditions in relation to science and innovation caused the need to integrate innovative priorities with environmental imperatives to support sustainable development of modern society. Thereby, the above-mentioned tendencies are also highly widespread at local (regional) level, because both innovation and environmental practices play an essential role for social development, economic growth, improved productivity and competitiveness, and improved quality of life. Thereby, research problem lays upon the regional environmental systems and their influence at innovative development in Ukraine. The paper aims to provide scientific support on environmental systems development and their connection with innovative development indicators at the regional level. The research methodology is based on official statistical data on Ukrainian economy innovativeness analysis during the last ten years. The environmental component is analyzed at the regional level that allowed us to rank Ukrainian regions in accordance with the level of their environmental responsibility, propose a measure of transformation to their strategies. As the result, the groups of regional environmental strategies were defined in accordance with criteria of their effectiveness and need of transformation. Thus, the research highlights the special status of environmental economy, based on its specific characteristics and influences at innovative development, including network effects, the ability to convert environmental and innovative benefits into significant social effects, hybrid and multiplicative.
Analysis of Co-Expression Module of Liver Metastasis Genes in Colorectal Cancer and Mining of Potential High-Expression Biomarkers

AimsThe Hub genes highly related to the disease were found from the gene co-expression module, and the potential high expression genes were analyzed to predict the liver metastasis of colorectal cancer, so as to provide reference for subsequent targeted therapy.MethodsIn this study, we used the public data set of GEO database (GSE50760) to analyze the gene co-expression of liver metastasis of colon cancer, primary colon cancer and normal colon tissue (54 cases) and 50 cases of clinical cases. The functional annotations based on GO database are enriched, and the functional annotations of five gene modules are obtained through the enrichment of biological processes. Then the data mining is carried out to find the sub-networks with high adjacency in the gene co-expression network. At the same time, these sub-networks are annotated to find oncogenes related to liver metastasis of colorectal cancer.ResultsThis experiment found that KRAS, APC, FBXW7, PIK3CA, TP53 were highly correlated with liver metastasis of colorectal cancer. Finally, two protein genes STAT1 and MAPK1 were found by MCODE, which may be highly correlated with liver metastasis of colorectal cancer. Two new genes with high expression proteins found in this experiment have potential cancer, which has not been reflected in previous studies.Conclusion﻿According to clinical data, KRAS, APC, FBXW7, PIK3CA, TP53 are related to colorectal cancer liver metastasis, and the analysis of the data set shows that STAT1 and MAPK1 are not only related to colorectal cancer liver metastasis oncogene but also related to clinically obtained genes.