Miracle-dz/UniFAR-FTUs huggingface dataset:
VeloTT tracking for LHCb Run II

This note describes track reconstruction in the LHCb tracking system upstream of the magnet, combining VELO tracks with hits in the TT sub-detector. The implementation of the VeloTT algorithm and its performance in terms of track reconstruction efficiency, ghost rate and execution time are presented. The algorithm has been rewritten for use in the first software trigger level for LHCb Run II. The momentum and charge information obtained for the VeloTT tracks (due to a fringe magnetic field between the VELO and TT sub-detectors) can reduce the total execution time for the full tracking sequence.
Dalbavancin is thermally stable at clinically relevant temperatures against methicillin-sensitive Staphylococcus Aureus

Abstract Introduction: While the rate of orthopaedic infections has remained constant over the years, the burden on healthcare systems continues to rise with an aging population. Local antibiotic delivery via polymethyl methacrylate bone cement is a common adjunct in treating bone and joint infections. Dalbavancin is a novel lipoglycopeptide antibiotic in the same class as vancomycin that has shown efficacy against Gram-positive organisms when used systemically but has not been investigated as a local antibiotic. This study aims to identify whether dalbavancin is thermally stable at the temperatures expected during the polymerization of polymethyl methacrylate cement. Methods: Stock solutions of dalbavancin were prepared and heated using a polymerase chain reaction machine based upon previously defined models of curing temperatures in two clinically relevant models: a 10 mm polymethyl methacrylate bead and a polymethyl methacrylate articulating knee spacer model. Aliquots of heated dalbavancin were then transferred to be incubated at core body temperature (37 ∘ C) and analyzed at various time points up to 28 d. The minimum inhibitory concentration at which 90 % of colonies were inhibited (MIC 90 ) for each heated sample was determined against methicillin-sensitive Staphylococcus aureus (American Type Culture Collection, ATCC, 0173K) using a standard microbroth dilution assay. Results: The average MIC 90 of dalbavancin was 1.63 µgmL-1 ±0.49 against 0173K S. aureus. There were no significant differences in the relative MIC 90 values after heating dalbavancin in either model compared to unheated control dalbavancin. Conclusions: Dalbavancin is thermally stable at the curing temperatures of polymethyl methacrylate cement and at human core body temperature over 28 d. Future in vitro and in vivo studies are warranted to further investigate the role of dalbavancin as a local antibiotic prior to its clinical use.
Serotonin Transporter Activity in Mouse Oocytes Is a Positive Indicator of Follicular Growth and Oocyte Maturity

Serotonin (5-hydroxytryptamine, 5-HT) is known to be a regulator of oocyte maturation in a large number of animal species. In maturing mammalian oocytes, the accumulation of exogenous, maternal serotonin occurs due to the activity of the membrane transporter SERT. In this work, we investigated how SERT activity in oocytes correlates with indicators of follicular selection and oocyte maturity. An immunohistochemical study showed that the difference in the 5-HT intake activity in oocytes does not correlate with the marker of apoptosis in follicular cells, but positively correlates with markers of follicular growth, such as granulosa proliferation and follicle size. Functional analysis of oocytes at different stages of maturation showed that the expression and activity of SERT increases with oocyte maturation. An in vivo experiment on administration of the selective serotonin reuptake inhibitor fluoxetine (20 mg/kg) for 7 days showed a significant decrease in the content of serotonin in both growing GV-oocytes and ovulated mature MII-oocytes. The data obtained clearly indicate that the mechanism of specific membrane transport of serotonin normally ensures the accumulation of serotonin in maturing oocytes, and can be considered as a promising positive marker of their mature status.
Some QPs, but Not All, Interact with Prosody

Unlike English, many scrambling languages including German, Russian and Japanese, have been acknowledged as showing scope rigidity. Thus, a sentence with multiple quantifiers as schematized in (1) is not ambiguous and surface scope (i.e. subject-wide scope) reading is only available. However, it has been also observed that inverse scope (i.e. object-wide scope) reading is also possible when the sentence is pronounced with certain prosody. In German, rising pitch accent on the subject QP and falling pitch accent on the object QP allows inverse scope reading (Büring 1994, Krifka 1998). In Russian, inverse scope is available when the pitch accent of the determiner of an in-situ object QP is removed (Antonyuk-Yudina 2011) or when the subject QP has contrastive focus accents (Ionin and Luchkina 2015). In Japanese, when a prominent accent is assigned on the subject quantifier followed by a pause (Kitagawa 1990), inverse reading is reported to be available. Even though the specific characteristic of prosody that ameliorates scope rigidity is different language by language, there seems a crucial common property in the inverse-reading inducing prosody: subject QP is prosodically accented (mostly by raising pitch range) and object QP is less (or de-) accented.
Investigation of cyto-toxicity of an innovative BIOfactor MTA product in different human cells: a pilot study

Objectives: The aim of this study was to investigate the cyto-toxicity of Biodentine, Angelus MTA, BIOfactor MTA on 3T3L-1 fibroblast, and Saos-2 osteosarcoma cell lines with different dilution of all products. Material and methods: 3T3-1 fibroblast was applied to stimulate pulp cells in cell viability test. In order to gene rate an osteoblastic cell-like model, only Saos-2 cells were used. MTT test was utilized to measure cell cytotoxicity in different dilution of all MTA products. SPSS package program was applied to perform Kruskal-Wallis, one-way ANOVA and two-way ANOVA tests. Results: According to results, while Biodentine, Angelus MTA and BIOfactor MTA showed cyto-toxic effects in 1 : 1 and 1 : 2 dilutions, they were not cyto-toxic in 1 : 4 and 1 : 8 dilutions. Conclusions: MTA products have similar cyto-toxicity. BIOfactor MTA has a cyto-toxic effect as other similar products.
Surface Electrical Impedance Myography Detects Skeletal Muscle Atrophy in Aged Wildtype Zebrafish and Aged gpr27 Knockout Zebrafish

Throughout a vertebrate organism’s lifespan, skeletal muscle mass and function progressively decline. This age-related condition is termed sarcopenia. In humans, sarcopenia is associated with risk of falling, cardiovascular disease, and all-cause mortality. As the world population ages, projected to reach 2 billion older adults worldwide in 2050, the economic burden on the healthcare system is also projected to increase considerably. Currently, there are no pharmacological treatments for sarcopenia, and given the long-term nature of aging studies, high-throughput chemical screens are impractical in mammalian models. Zebrafish is a promising, up-and-coming vertebrate model in the field of sarcopenia that could fill this gap. Here, we developed a surface electrical impedance myography (sEIM) platform to assess skeletal muscle health, quantitatively and noninvasively, in adult zebrafish (young, aged, and genetic mutant animals). In aged zebrafish (~85% lifespan) as compared to young zebrafish (~20% lifespan), sEIM parameters (2 kHz phase angle, 2 kHz reactance, and 2 kHz resistance) robustly detected muscle atrophy (p < 0.000001, q = 0.000002; p = 0.000004, q = 0.000006; p = 0.000867, q = 0.000683, respectively). Moreover, these same measurements exhibited strong correlations with an established morphometric parameter of muscle atrophy (myofiber cross-sectional area), as determined by histological-based morphometric analysis (r = 0.831, p = 2 × 10−12; r = 0.6959, p = 2 × 10−8; and r = 0.7220; p = 4 × 10−9, respectively). Finally, the genetic deletion of gpr27, an orphan G-protein coupled receptor (GPCR), exacerbated the atrophy of skeletal muscle in aged animals, as evidenced by both sEIM and histology. In conclusion, the data here show that surface EIM techniques can effectively discriminate between healthy young and sarcopenic aged muscle as well as the advanced atrophied muscle in the gpr27 KO animals. Moreover, these studies show how EIM values correlate with cell size across the animals, making it potentially possible to utilize sEIM as a “virtual biopsy” in zebrafish to noninvasively assess myofiber atrophy, a valuable measure for muscle and gerontology research.
Locative prepositions, predicate inversion and Full Interpretation*

This paper studies the relation between the two structures in which Greek locative Prepositions participate. I investigate the possibility that Complex Preposition structures derive from the structure in which the locative is followed by a genitive clitic via Predicate Inversion, and reject it in view of the fact that the locative can appear stranded. I consider it more possible for the genitive clitic structure to derive from the Complex Preposition structure via omission of the light P. Support for this idea is offered by the fact that the former structure is not available when the light P of the corresponding Complex Preposition is not ‘light’.
Cultural adaptation and validation of the Brazilian Portuguese version of the PROactive Physical Activity in COPD-clinical visit instrument for individuals with COPD

ABSTRACT Objective: To adapt the PROactive Physical Activity in COPD-clinical visit (C-PPAC) instrument to the cultural setting in Brazil and to determine the criterion validity, test-retest reliability agreement, and internal consistency of this version. Methods: A protocol for cultural adaptation and validation was provided by the authors of the original instrument and, together with another guideline, was applied in a Portuguese-language version developed by a partner research group from Portugal. The adapted Brazilian Portuguese version was then cross-sectionally administered twice within a seven-day interval to 30 individuals with COPD (57% were men; mean age was 69 ± 6 years; and mean FEV1 was 53 ± 18% of predicted) to evaluate internal consistency and test-retest reliability. Participants also completed the International Physical Activity Questionnaire (IPAQ), the modified Medical Research Council scale, the COPD Assessment Test, and Saint George’s Respiratory Questionnaire to evaluate criterion validity. Results: The C-PPAC instrument showed good internal consistency and excellent test-retest reliability: “amount” domain = 0.87 (95% CI, 0.73-0.94) and “difficulty” domain = 0.90 (95% CI, 0.76-0.96). Bland & Altman plots, together with high Lin’s concordance correlation coefficients, reinforced that agreement. Criterion validity showed moderate-to-strong correlations of the C-PPAC with all of the other instruments evaluated, especially with the IPAQ (rho = −0.63). Conclusions: The Brazilian Portuguese version of the C-PPAC is a reliable and valid instrument for evaluating the experience of Brazilian individuals with COPD with their physical activity in daily life.
Mechatronic linear movement device for constructing surfaces of complex shapes with the possibility of force measurement

In the modern world, there is a trend towards the introduction of mechatronics in an increasing number of areas of science and technology in order to solve complex problems of controlling functional movements. One of these problems is the problem of forming surfaces of complex shapes. This task is relevant in many areas of human activity such as industry, art, and human-machine interfaces. However, among the existing solutions, there are none that could provide the possibility of forming complex surfaces under the influence of a load, while providing compact weight-dimensional characteristics. The purpose of this article is to develop the concept of a mechatronic device for the tasks of constructing surfaces of complex shape with high accuracy, the possibility of positioning under a large axial load, and measuring the axial forces exerted by objects of manipulation. The article selects the initial design parameters based on the analysis of devices similar in functionality. Next, the selection of compo-nents, the development of the layout of functional components, control electronics, and design, and the implemen-tation of a 3D model of the final device are carried out. It also describes a method for managing a group of re-ceived mechatronic devices by using a single data bus with a specialized protocol.
ACL-Net: Semi-supervised Polyp Segmentation via Affinity Contrastive Learning

Automatic polyp segmentation from colonoscopy images is an essential prerequisite for the development of computer-assisted therapy. However, the complex semantic information and the blurred edges of polyps make segmentation extremely difficult. In this paper, we propose a novel semi-supervised polyp segmentation framework using affinity contrastive learning (ACL-Net), which is implemented between student and teacher networks to consistently refine the pseudo-labels for semi-supervised polyp segmentation. By aligning the affinity maps between the two branches, a better polyp region activation can be obtained to fully exploit the appearance-level context encoded in the feature maps, thereby improving the capability of capturing not only global localization and shape context, but also the local textural and boundary details. By utilizing the rich inter-image affinity context and establishing a global affinity context based on the memory bank, a cross-image affinity aggregation (CAA) module is also implemented to further refine the affinity aggregation between the two branches. By continuously and adaptively refining pseudo-labels with optimized affinity, we can improve the semi-supervised polyp segmentation based on the mutually reinforced knowledge interaction among contrastive learning and consistency learning iterations. Extensive experiments on five benchmark datasets, including Kvasir-SEG, CVC-ClinicDB, CVC-300, CVC-ColonDB and ETIS, demonstrate the effectiveness and superiority of our method. Codes are available at https://github.com/xiewende/ACL-Net.
Praktik Menuju Vagina yang Sempurna: Pendisiplinan dengan Beragam Produk untuk Daerah Kewanitaan

AbstrakTubuh dan seksualitas perempuan selalu diatur mengikuti konstruksi yang berkembang di dalam masyarakat. Dalam hal kenikmatan seksual perempuan dituntut untuk bisa memuaskan pasangannya. Salah satu cara yang dilakukan adalah dengan memiliki penampilan yang menarik seperti yang diidealkan dalam masyarakat. Tidak hanya pada penampilan luarnya saja namun tuntutan tersebut juga berlaku untuk bagian tubuh yang paling private dari perempuan. Vagina sebagai organ yang paling intim juga mendapatkan pendisiplinan di dalam masyarakat. Penelitian ini dilakukan secara kualitatif dengan melihat praktik penggunaan produk-produk khusus untuk vagina yang dilakukan oleh para perempuan muda yang sudah memiliki aktifitas seksual yang aktif namun belum menikah. Pada akhirnya kesebelas perempuan muda sebagai informan penelitian, mencoba untuk memenuhi tuntutan yang terbentuk dalam konstruksi di masyarakat berkaitan dengan vaginanya. Cara yang mereka pilih adalah dengan memaksimalkan vaginanya menggunakan beragam produk-produk kimia khusus untuk vagina. Kata Kunci: seksualitas, vagina, pendisiplinan, dan produk kimia
Effect of Maturity Status and Relative Age Effect on Anthropometrics and Physical Performance of Soccer Players Aged 12 to 15 Years

Introduction: There is a growing interest in the relationship between biological maturation, relative age effect, and soccer sports performance. Based on their cohort's relative age effect and maturation, relatively older soccer players can be favored to be selected for high-level teams. Therefore, the current study examined the effect of maturity and relative age on anthropometric and physical performance tests. Methods: A cross-sectional study involving 82 boys (M age: 13.4 ± 1.1; M body mass: 51.9 ± 9.9; body height: 162 ± 10.5; body fat%: 9.7 ± 1.1) were assessed for anthropometric, flexibility, hand, and leg strength, and countermovement jump performance. Peak height velocity (PHV) determination was used for maturity status estimation. The birthdate distributions were categorized into four quartiles (January-March, Q1; April-June, Q2; July-September, Q3; October-December, Q4). MANOVA analysis was performed on all anthropometric and physical performance assessments to examine differences within age groups and maturity status groups. Differences among all groups were revealed, with high scores in the older group (U-15). Results: Biological maturation influences the differences in the anthropometric and physical performance assessment with a significant effect on the early matured soccer players compared to the late matured. Early matured players were overrepresented and statistically had better anthropometric and physical performance results. Conclusion: However, there was no significant representation of players in the first quarter compared to the third and fourth quarters for all the anthropometric and performance assessments. The current findings can be used for quantifying and controlling performance data of soccer players adjusted to biological requirements used in the training process.
Expected Performance of the ATLAS Inner Tracker at the High Luminosity LHC

The large data samples at the High-Luminosity LHC will enable precise measurements of the Higgs boson and other Standard Model particles, as well as searches for new phenomena such as supersymmetry and extra dimensions. To cope with the difficult challenges such as large radiation doses and high pileup, during Phase II of the ATLAS upgrade the current Inner Detector will be replaced with a new all-silicon Inner Tracker. The current tracking performance of two candidate Inner Tracker layouts with a wide acceptance of |η| < 4.0, employing either an Extended or Inclined Pixel barrel, is evaluated. The forward coverage would enable track-based rejection of forward pileup jets, which is particularly beneficial for studies of vector boson scattering and Higgs boson production through vector boson fusion. Table 2 has been updated to correct a typographical error: the maximum |z| position of the modules in Pixel endcap layer 1 is 3000 mm, not 2596 mm. c © 2016 CERN for the benefit of the ATLAS Collaboration. Reproduction of this article or parts of it is allowed as specified in the CC-BY-4.0 license.
Multifunctionality in Nature: Structure–Function Relationships in Biological Materials

Modern material design aims to achieve multifunctionality through integrating structures in a diverse range, resulting in simple materials with embedded functions. Biological materials and organisms are typical examples of this concept, where complex functionalities are achieved through a limited material base. This review highlights the multiscale structural and functional integration of representative natural organisms and materials, as well as biomimetic examples. The impact, wear, and crush resistance properties exhibited by mantis shrimp and ironclad beetle during predation or resistance offer valuable inspiration for the development of structural materials in the aerospace field. Investigating cyanobacteria that thrive in extreme environments can contribute to developing living materials that can serve in places like Mars. The exploration of shape memory and the self-repairing properties of spider silk and mussels, as well as the investigation of sensing–actuating and sensing–camouflage mechanisms in Banksias, chameleons, and moths, holds significant potential for the optimization of soft robot designs. Furthermore, a deeper understanding of mussel and gecko adhesion mechanisms can have a profound impact on medical fields, including tissue engineering and drug delivery. In conclusion, the integration of structure and function is crucial for driving innovations and breakthroughs in modern engineering materials and their applications. The gaps between current biomimetic designs and natural organisms are also discussed.
Radiation spectrum of system of electrons moving in spiral in medium

The structure of spectral distribution of the radiation power of the synchrotron-Cherenkov radiation of one, two, three, and four electrons moving in a spiral in a transparent medium with relativistic longitudinal velocity component (the component parallel to the magnetic induction vector) is researched. The influence of the coherence factor on the spectrum of synchrotron-Cherenkov radiation for two, three, and four electrons is analyzed.
Unit Root Testing in Multiple Smooth Break Models with Nonlinear Dynamics

This work builds a flexible model accommodating nonlinear dynamics around a trend function with multiple (up to m) gradual shifts. Such a model is suitable for capturing the behavior of many post World War II economic time‐series subject to the onset of external causes such as oil crises, financial crises, technology changes and regulatory changes. Deriving unit root tests in this nonlinear model is of particular interest. In fact, the options of a general trend specification and nonlinear dynamics are critical to remedy unit root tests not being biased toward a non‐rejection of a unit root hypothesis and prevents the first‐differences of a series from being used too often. An asymptotic theory for the unit root tests is also established. The unit root tests are applied to G7 industrial production series, and evidence in favor of nonlinear trend ‘stationary’ models is found in a majority of the cases. The merits of the new model are further demonstrated in an estimation exercise for the US industrial production series, and evidence of four gradual shifts in the trend, different growth patterns for different periods, and business cycle asymmetries is found.
Meteodiversity: a new concept for quantifying meteorological diversity

Inspired by the concept of biodiversity used by biologists and ecologists, the concept of meteodiversity is proposed as a method of characterising the variety of meteorological phenomena in a defined area within a specified period. Similarly to the term biodiversity, meteodiversity takes into account the proportion of individual meteorological phenomena belonging to the main weather that occur in a defined area. The benefits and importance of using this concept are discussed.
Nanophotonics and hybrid plasmonics: different technologies and applications

This paper gives a review of the recent progresses in our research on nanophotonics and hybrid plasmonic geometries, structures and devices. In the first part we present SOI-nanowire-based integrated components. The concept and different configurations of hybrid plasmonic structures will be then discussed. Finally different fabricated devices for applications in optical interconnects and sensing will be presented and characterized.
Enabling a new degree of wave control with metamaterials: a personal perspective

Metamaterials represent an exciting area of research, which has rapidly evolved in the past two decades from basic research to applied technology, and it now encompasses a broad range of scientific communities, with continuous and exciting scientific progress. Our personal journey in the field of artificial materials and metamaterials spans over many years, and has brought us through an exciting adventure in the theoretical understanding of wave interactions with materials, with several implications for new devices and components for radio-wave, infrared, optical and acoustic technology. In this paper, we provide a brief overview of some highlights of our contribution to this area of research, looking forward to several exciting opportunities for further scientific and technical progress in this area of science and technology.