Miracle-dz/UniFAR-FTUs huggingface dataset:
The Role of Methionine-Rich Diet in Unhealthy Cerebrovascular and Brain Aging: Mechanisms and Implications for Cognitive Impairment

As aging societies in the western world face a growing prevalence of vascular cognitive impairment and Alzheimer’s disease (AD), understanding their underlying causes and associated risk factors becomes increasingly critical. A salient concern in the western dietary context is the high consumption of methionine-rich foods such as red meat. The present review delves into the impact of this methionine-heavy diet and the resultant hyperhomocysteinemia on accelerated cerebrovascular and brain aging, emphasizing their potential roles in cognitive impairment. Through a comprehensive exploration of existing evidence, a link between high methionine intake and hyperhomocysteinemia and oxidative stress, mitochondrial dysfunction, inflammation, and accelerated epigenetic aging is drawn. Moreover, the microvascular determinants of cognitive deterioration, including endothelial dysfunction, reduced cerebral blood flow, microvascular rarefaction, impaired neurovascular coupling, and blood–brain barrier (BBB) disruption, are explored. The mechanisms by which excessive methionine consumption and hyperhomocysteinemia might drive cerebromicrovascular and brain aging processes are elucidated. By presenting an intricate understanding of the relationships among methionine-rich diets, hyperhomocysteinemia, cerebrovascular and brain aging, and cognitive impairment, avenues for future research and potential therapeutic interventions are suggested.
Lung adenocarcinoma and splenic histiocytic sarcoma in an African pygmy hedgehog (Atelerix albiventris)

The African pygmy hedgehog is increasingly being kept as a pet, and studies regarding the primary diseases that affect this species are essential for advancing medicine in these animals. This report aims to describe a case of an adult male hedgehog living in captivity. The hedgehog presented progressive weight loss and lethargy. An abdominal ultrasound examination was performed, revealing a splenic mass. Therefore, symptomatic treatment was chosen. After three months, with no clinical improvement, the animal was euthanized. The cadaver underwent necropsy, and histopathological evaluation with Hematoxylin and Eosin staining revealed two distinct neoplasms in different organs: pulmonary adenocarcinoma and round cell neoplasm in the spleen. Additionally, non-neoplastic lesions were observed in other organs. The splenic tissue was subjected to an immunohistochemical diagnostic panel using IBA1, CD3, PAX5, MUM1, and AE1AE3 markers. Positive staining for IBA1 was observed, favoring the diagnosis of histiocytic sarcoma. We emphasize the importance of preventive veterinary medicine in assessing these animals' health status and detecting possible neoplastic processes. Tumors are commonly described in this species, and clinical signs usually are nonspecific, leading to the animal's death or euthanasia.
FTM-Sense: Robust Sensor-free Occupancy Sensing Leveraging WiFi Fine Time Measurement

Occupancy detection is vital in optimizing smart building applications, such as automatic heating/cooling, lighting systems, and energy management. Conventional occupancy sensing approaches have limitations, such as inadequate performance with stationary occupants, susceptibility to environmental factors, and limited adaptability to various indoor environments. To address these limitations, we propose FTM-Sense, a real-time adaptable sensor-free occupancy detection system by employing the WiFi fine time measurement (FTM) protocol. Our proposed system leverages the variations in FTM measurements caused by human body presence for occupancy detection purposes. FTM-Sense has the advantage of accurately detecting static occupants, and demonstrating robustness and adaptability to various indoor environments. Experimental results show that FTM-Sense achieves a 97.72% overall accuracy, with 97.68% accuracy in detecting static occupants. Furthermore, the system dynamically adapts to room configuration changes within 80 seconds without compromising detection performance. FTM-Sense is tested in both residential and office buildings, collecting over 17 hours of data in seven different rooms with varying sizes and characteristics while also evaluating three different materials for blockage in non-line-of-sight (NLOS) scenarios. This research presents a promising solution for reliable and adaptable sensor-free occupancy detection, contributing to energy management and building cost reduction.
ESP Teachers’ Practice of Developing Curriculum at some Universities in Ho Chi Minh City

ESP curriculum development is of great significance in terms of developing a curriculum that meets the specific needs of a learner group as well as enhances relevance and students’ interest and motivation. Teacher involvement in this process is essential in that not many materials are available for leaners with specific needs and an ESP teacher is not only a teacher but also a collaborator, a course designer and material provider, a researcher, and an evaluator (Dudley-Evans & St. John, 1998). The study thus aims to investigate ESP teachers’ practice in the curriculum development process. Seventy eight teachers at four tertiary institutions in Ho Chi Minh City were asked about their involvement in the process of developing the ESP curriculum for non-English majors at their universities through a questionnaire and interviews. The data were then analyzed to show in which steps and how the teachers are involved in the ESP curriculum development process; the findings were discussed and some suggestions given to inform the ESP curriculum development process.
Ontology of language, with applications to demographic data

Here we present what we believe is a novel account of what languages are, along with an axiomatically rich representation of languages and language-related data that is based on this account. We propose an account of languages as aggregates of dispositions distributed across aggregates of persons, and in doing so we address linguistic competences and the processes that realize them. This paves the way for representing additional types of language-related entities. Like demographic data of other sorts, data about languages may be of use to researchers in a number of areas, including biomedical research. Data on the languages used in clinical encounters are typically included in medical records, and capture an important factor in patient-provider interactions. Like many types of patient and demographic data, data on a person’s preferred and primary languages are organized in different ways by different systems. This can be a barrier to data integration. We believe that a robust framework for representing language in general and preferred and primary language in particular – which has been lacking in ontologies thus far – can promote more successful integration of language-related data from disparate data sources.
PAISAJES URBANOS E INJUSTICIA ESPACIAL: REDISTRIBUCIÓN ESPACIAL DE INGRESOS SUPLETORIOS . Metodología para la redistribución de ingresos supletorios generados por bienes públicos locales

The study aims to introduce a methodology for a spatial redistribution of supplementary incomes generated by new or renovated local public goods (LPGs) and shows how its application promotes spatial justice in the cities. Two models were developed for establishing land and real estate prices (LEnP) variation and estimating the supplementary income associated to new LPGs. These models were applied to stations of BRT-TM Transmilenio system in Bogotá and to 108,888 estate appraisals (2004-2018) distributed throughout the city. It was found that benefits associated to BRT stations extend up to 0.5 km from the BRT stations and it was estimated that the LEnP increase (supplementary income) 3% on average (maximum: 8%, distance 0 km; minimum: 0%, distance > 0.5km). The redistribution methodology integrates incident citizen participation processes to allocate resources that finance LPGs in low-income urban peripheries. Keywords: Spatial Redistribution of Income, Spatial Justice, Urban Development, Surplus Value. Este estudio presenta una metodología para la redistribución espacial de los ingresos supletorios generados por nuevos, o mejorados, bienes públicos locales (BPL) y muestra cómo su aplicación promueve la justicia espacial en las ciudades. Se desarrollaron dos modelos para establecer la variación en los precios del suelo y de los predios (PSyP) y estimar los ingresos supletorios asociados a los nuevos BPL. En estos modelos se utilizaron, como BPL, las estaciones del sistema BRT-TM Transmilenio en Bogotá y 108.888 avalúos comerciales (2004-2018) de predios distribuidos por toda la ciudad. Se encontró que los beneficios de las estaciones del BRT se extienden hasta 0,5 km y se estimó que los PSyP se incrementan (ingresos supletorios) 3% en promedio (máximo: 8%, distancia 0 km; mínimo: 0%, distancia > 0,5km). La metodología de redistribución integra procesos de participación ciudadana incidente para asignar recursos que financien BPL en las periferias urbanas de bajos ingresos. Palabras clave: redistribución espacial del ingreso, justicia espacial, desarrollo urbano, plusvalía.
NASA-F: FPGA-Oriented Search and Acceleration for Multiplication-Reduced Hybrid Networks

The costly multiplications challenge the deployment of modern deep neural networks (DNNs) on resource-constrained devices. To promote hardware efficiency, prior works have built multiplication-free models. However, they are generally inferior to their multiplication-based counterparts in accuracy, calling for multiplication-reduced hybrid models to marry the benefits of both approaches. To achieve this goal, recent works, i.e., NASA and NASA+, have developed <underline>N</underline>eural <underline>A</underline>rchitecture <underline>S</underline>earch (NAS) and <underline>A</underline>cceleration frameworks to search for and accelerate such hybrid models via a tailored differentiable NAS (DNAS) engine and dedicated ASIC-based accelerators. In this paper, we delve deeper into the inherent advantages of FPGAs and present an enhanced approach called NASA-F, which focuses on FPGA-oriented search and acceleration for hybrid models. Specifically, <underline>on the algorithm level</underline>, we develop a tailored one-shot supernet-based NAS engine to streamline the search for hybrid models, eliminating the need for executing NAS for each deployment as well as additional training/finetuning steps. <underline>On the hardware level</underline>, we develop a chunk-based accelerator to fully leverage the diverse hardware resources available on FPGAs for the acceleration of heterogeneous layers in hybrid models, aiming to enhance both hardware utilization and throughput. Extensive experimental results consistently validate the superiority of our NASA-F framework, e.g., we can gain <inline-formula> <tex-math notation="LaTeX">$\uparrow 0.67\%$ </tex-math></inline-formula> top-1 accuracy over the prior work NASA on CIFAR100 even without additional training steps for searched models. Additionally, we can achieve up to <inline-formula> <tex-math notation="LaTeX">$\uparrow 1.86\times $ </tex-math></inline-formula> throughout and <inline-formula> <tex-math notation="LaTeX">$\uparrow 2.16\times $ </tex-math></inline-formula> FPS with <inline-formula> <tex-math notation="LaTeX">$\uparrow 0.39$ </tex-math></inline-formula>% top-1 accuracy over the state-of-the-art multiplication-based system on Tiny-ImageNet. Codes are available at <uri>https://github.com/shihuihong214/NASA-F</uri>.
Health System for Exercise Rehabilitation Detection Retina Images and IoT Blockchain

Smart Healthcare which is based on deep learning is becoming increasingly popular because of its practical applications and has grown popular after its incorporation with IoT. Degenerative eye disease is the main factor of blindness in people of working age. Asian nations with large populations, like India and China, are on the edge of a diabetes epidemic. In terms of medical screening and diagnosis, a large number of diabetes patients posed a huge problem for skilled clinicians. The idea is to employ deep learning algorithms to detect blind spots in the eye and estimate the severity of the stage. We present an optimum approach for detecting blindness in retinal images based on recently released pre-trained EfficientNet models, as well as a comparative assessment of many innovative neural network models, in this study. On a benchmark dataset of retina images obtained by diagnostic imaging at various imaging phases, our EfficientNet-B5-based model assessment performs better than CNN and ResNet50 models.
Participatory evaluation and demonstration of productive performance of Bovans Brown chicken under village production system in Menit Shasha Woreda, West Omo Zone, Ethiopia

The study was conducted in Charuhurit kebele in Menit Shasha woreda West Omo Zone, south west region (SWR) Ethiopia. Beforethe commencement of the study need assessment was done on existing livestock production system and their constraints throughconducting group discussion with pastoralists, then the pastoralists were prioritized poultry production system as major problem needimmediate intervention. A pastoralist and agro-pastoralist extension research group (PAPREG) which containing 25 pastoralists wereestablished and randomly assigned to different production system (10 intensive productions, 10 semi intensive and five extensiveproduction system). 125 pullets of Bovan Brown chicken breed age 75 days purchased from Bushoftu Alema farm were distributed andbefore distribution training on housing, feeding, health and overall handling system of animals were given for pastoralists. The studyrevealed that high mortality rate or low survivability rate was observed before the onset egg production in the study area. There wereno significant differences in age of animals before onset of egg lying, but number of egg produced every month was significantly (p< 0.05) higher between production systems. The average age at onset of egg lying was 22.10 weeks. The result shown that significantly(p < 0.05) higher number (23.77) of eggs per month per hen was recorded for intensive production system. Finally, the authors concludedthat Bovan Brown chicken breed under village production in terms of their egg production performance were feasible in the study areato enhance family nutrition and income generations.
Disturbance and Ecosystem Functioning: the Role of Changes in Benthic Biological Traits

Rapid changes in biodiversity are occurring globally, as a consequence of anthropogenic disturbance. This has raised concerns, since biodiversity is known to significantly contribute to ecosystem functions and services. Marine benthic communities participate in numerous functions provided by soft-sedimentary ecosystems. Eutrophication-induced oxygen deficiency is a growing threat against infaunal communities, both in open sea areas and in coastal zones. There is thus a need to understand how such disturbance affects benthic communities, and what is lost in terms of ecosystem functioning if benthic communities are harmed. In this thesis, the status of benthic biodiversity was assessed for the open Baltic Sea, a system severely affected by broad-scale hypoxia. Long-term monitoring data made it possible to establish quantitative biodiversity baselines against which change could be compared. The findings show that benthic biodiversity is currently severely impaired in large areas of the open Baltic Sea, from the Bornholm Basin to the Gulf of Finland. The observed reduction in biodiversity indicates that benthic communities are structurally and functionally impoverished in several of the sub-basins due to the hypoxic stress. A more detailed examination of disturbance impacts (through field studies and experiments) on benthic communities in coastal areas showed that changes in benthic community structure and function took place well before species were lost from the system. The degradation of benthic community structure and function was directed by the type of disturbance, and its specific temporal and spatial characteristics. The observed shifts in benthic trait composition were primarily the result of reductions in species’ abundances, or of changes in demographic characteristics, such as the loss of large, adult bivalves. Reduction in community functions was expressed as declines in the benthic bioturbation potential and in secondary biomass production. The benthic communities and their degradation accounted for a substantial proportion of the changes observed in ecosystem multifunctionality. Individual ecosystem functions (i.e. measures of sediment ecosystem metabolism, elemental cycling, biomass production, organic matter transformation and physical structuring) were observed to differ in their response to increasing hypoxic disturbance. Interestingly, the results suggested that an impairment of ecosystem functioning could be detected at an earlier stage if multiple functions were considered. Importantly, the findings indicate that even small-scale hypoxic disturbance can reduce the buffering capacity of sedimentary ecosystem, and increase the susceptibility of the system towards further stress. Although the results of the individual papers are context-dependent, their combined outcome implies that healthy benthic communities are important for sustaining overall ecosystem functioning as well as ecosystem resilience in the Baltic Sea.
Fostering Critical Thinking Skills in the EFL College-Level Classroom Through Online Collaborative Document Tools

This paper explores the potential of applying online collaborative documents to foster critical thinking skills in EFL college-level classrooms. Considering the limitations of traditional teacher-centered approaches and the need for innovative methods, the study examines the integration of online collaborative tools, using Tencent Docs as an example. The discussion highlights the importance of critical thinking in the academic and professional spheres and introduces the concept of online collaborative documents for enhancing this cognitive skill. Through a detailed exploration, the paper presents a model of employing collaborative documents within a college English class, demonstrating how students collaboratively learning an article. Then, the paper discusses the pros and cons of employing this technology in classroom. The conclusion emphasizes the transformative potential of integrating technology into pedagogy and its role in creating a dynamic learning environment. The paper underscores the importance of striking a balance between technology and traditional methods, foreseeing avenues for further research and development.
Low-dose nivolumab and cabozantinib in recurrent intestinal-type papillary adenocarcinoma of the sinonasal region

Intestinal-type sinonasal adenocarcinoma is a rare epithelial malignancy primarily treated with surgery and chemoradiation. The combination of low-dose immunotherapy and a tyrosine kinase inhibitor in recurrent disease has not been previously studied. A man in his 20s with papillary adenocarcinoma of the sinonasal region, following surgical resection, was treated with six cycles of concurrent chemoradiotherapy, followed by four cycles of docetaxel, cisplatin and capecitabine. While on treatment, he was found to have extensive residual disease and he was started on low-dose nivolumab and cabozantinib. Repeat imaging after ten months of treatment revealed a significant reduction in lesions. Non-squamous head and neck cancers are often excluded from major trials, and the effect of immunotherapy in these histologies is poorly understood. The response seen with low-dose immunotherapy underscores the need for further research in this setting.
Biomass burning dominates brown carbon absorption in the rural southeastern United States

Brown carbon aerosol consists of light‐absorbing organic particulate matter with wavelength‐dependent absorption. Aerosol optical extinction, absorption, size distributions, and chemical composition were measured in rural Alabama during summer 2013. The field site was well located to examine sources of brown carbon aerosol, with influence by high biogenic organic aerosol concentrations, pollution from two nearby cities, and biomass burning aerosol. We report the optical closure between measured dry aerosol extinction at 365 nm and calculated extinction from composition and size distribution, showing agreement within experiment uncertainties. We find that aerosol optical extinction is dominated by scattering, with single‐scattering albedo values of 0.94 ± 0.02. Black carbon aerosol accounts for 91 ± 9% of the total carbonaceous aerosol absorption at 365 nm, while organic aerosol accounts for 9 ± 9%. The majority of brown carbon aerosol mass is associated with biomass burning, with smaller contributions from biogenically derived secondary organic aerosol.
Regional significance of new U–Pb age data for Neoproterozoic igneous units in Avalonian rocks of northern mainland Nova Scotia, Canada

Gondwanan Neoproterozoic tectonothermal events (Pan-African and Brasiliano) are represented in northern mainland of Nova Scotia by volcanic and sedimentary rocks assigned to the Jeffers and Georgeville groups and by gabbroic to granitoid plutons. These rocks comprise part of Avalonia, an exotic terrane in the Appalachian orogen that was deposited in an arc-related environment along the periphery of Gondwana prior to accretion to Laurentia. Lavas sampled in the basal units of the Jeffers and Georgeville groups yielded slightly discordant U–Pb zircon and monazite data that fall on chords with upper intercept ages of 628 Ma and 617.7±1.6 Ma, respectively. Syntectonic to late syntectonic plutons intruded into these groups yielded U–Pb zircon ages of 606.6±1.6 Ma and 603+9−5 Ma. The former intrusion also yielded a concordant titanite age of 607±3 Ma. When combined with previously published ages, these data indicate that the back-arc deposition recorded in these groups lasted 10–15 million years (628–613 Ma) and was closely followed by c. 613–595 Ma metamorphism, intrusion and heterogeneous strike-slip related deformation. Assuming no significant shuffling of fault blocks, the relative locations of the Cobequid–Antigonish back-arc basin and the southern Cape Breton Island volcanic arc are consistent with their genesis above a north-west-dipping subduction zone. The age range of arc-related magmatism in Nova Scotia is similar to that of Avalonian rocks in southeastern Newfoundland and Britain, lending support to hypotheses of Neoproterozoic linkages.
A Rationale for Increasing Physical Activity in Chronic Kidney Disease: Quality Insights Renal Network 3’s Learning and Action Network’s Campaign

Individuals diagnosed with chronic kidney disease (CKD) are often reluctant to engage in physical activity. Research has demonstrated myriad physical and psychological health benefits of regular exercise in this population. The challenge for many renal care providers has been translating these benefits for patients in a manner that engages them in the process. Quality Insights Renal Network 3 (QIRN3) worked with in-center hemodialysis providers to promote increased physical activity with patients within the network. These patients were provided with education about the benefits of increasing physical activity and were asked to sign pledge cards indicating their goals in this regard. The final results of this campaign showed 42.3% of patients in the targeted facilities signed pledge cards indicating their plans to increase their physical activity and well-being.