Miracle-dz/UniFAR-FTUs huggingface dataset:
Sex and gender in pulmonary arterial hypertension

Pulmonary arterial hypertension (PAH) is a rare disease characterised by pulmonary vascular remodelling and elevated pulmonary pressure, which eventually leads to right heart failure and death. Registries worldwide have noted a female predominance of the disease, spurring particular interest in hormonal involvement in the disease pathobiology. Several experimental models have shown both protective and deleterious effects of oestrogens, suggesting that complex mechanisms participate in PAH pathogenesis. In fact, oestrogen metabolites as well as receptors and enzymes implicated in oestrogen signalling pathways and associated conditions such as BMPR2 mutation contribute to PAH penetrance more specifically in women. Conversely, females have better right ventricular function, translating to a better prognosis. Along with right ventricular adaptation, women tend to respond to PAH treatment differently from men. As some young women suffer from PAH, contraception is of particular importance, considering that pregnancy in patients with PAH is strongly discouraged due to high risk of death. When contraception measures fail, pregnant women need a multidisciplinary team-based approach. This article aims to review epidemiology, mechanisms underlying the higher female predominance, but better prognosis and the intricacies in management of women affected by PAH. Pulmonary arterial hypertension affects women more than men, although women have a better prognosis. Oestrogens might be the key to explain these gender differences. https://bit.ly/36KK1yX
Functional Genomics of a Symbiotic Community: Shared Traits in the Olive Fruit Fly Gut Microbiota

The olive fruit fly Bactrocera oleae is a major pest of olives worldwide and houses a specialized gut microbiota dominated by the obligate symbiont “Candidatus Erwinia dacicola”. Ca. E. dacicola is required for juvenile development in ripening olives and is thought to supplement dietary nitrogen in adults, with only indirect evidence for this hypothesis so far. Here, we sought to functionally investigate the symbiosis and its contribution to insect fitness. Inspection of three available Ca. E. dacicola genomes and one transcriptome provided evidence that the symbiont can hydrolyze urea for use as a nitrogen source, most probably by the adult insect: A urease operon was identified, not expressed at the juvenile stage, for which we provide evidence for a likely acquisition by horizontal gene transfer. Moreover, to explore the ecology of the B. oleae gut, we examined the composition of bacterial communities associated with Cretan olive fruit fly populations. We identified and reconstructed the genome of a novel component of the gut microbiota, Tatumella sp. TA1, which is stably associated with Mediterranean olive fruit fly populations. We further detected, in the genomes of both obligate and facultative members of the gut microbiota, components of extracellular surface structures, which may mediate interactions with the host and between microbes, including the exchange of genetic material. Our findings suggest that urea hydrolysis is a conserved functional trait for microbes stably inhabiting the B. oleae gut, and that genetic exchanges between microbes may have shaped the symbiosis between B. oleae and Ca. E. dacicola.
Short circuit modeling of wind turbine generators

Modeling of wind farms to determine their short circuit contribution in response to faults is a crucial part of system impact studies performed by power utilities. Short circuit calculations are necessary to determine protective relay settings, equipment ratings and to provide data for protection coordination. The plethora of different factors that influence the response of wind farms to short circuits makes short circuit modeling of wind farms an interesting, complex, and challenging task. Low voltage ride through (LVRT) requirements make it necessary for the latest generation of wind generators to be capable of providing reactive power support without disconnecting from the grid during and after voltage sags. If the wind generator must stay connected to the grid, a facility has to be provided to by-pass the high rotor current that occurs during voltage sags and prevent damage of the rotor side power electronic circuits. This is done through crowbar circuits which are of two types, namely active and passive crowbars, based on the power electronic device used in the crowbar triggering circuit. Power electronics-based converters and controls have become an integral part of wind generator systems like the Type 3 doubly fed induction generator based wind generators. The proprietary nature of the design of these power electronics makes it difficult to obtain the necessary information from the manufacturer to model them accurately. Also, the use of power electronic controllers has led to phenomena such as sub-synchronous control interactions (SSCI) in series compensated Type 3 wind farms which are characterized by non-fundamental frequency oscillations. SSCI affects fault current magnitude significantly and is a crucial factor that cannot be ignored while modeling series compensated Type 3 wind farms. These factors have led to disagreement and inconsistencies about which techniques are appropriate for short circuit modeling of wind farms. Fundamental frequency models like voltage behind transient reactance model are incapable of representing the majority of critical wind generator fault characteristics such as sub-synchronous interactions. The Detailed time domain models, though accurate, demand high levels of computation and modeling expertise. Voltage dependent current source modeling based on look up tables are not stand-alone models and provide only a black-box type of solution. The short circuit modeling methodology developed in this research work for representing a series compensated Type 3 wind farm is based on the generalized averaging theory, where the system variables are represented as time varying Fourier coefficients known as dynamic phasors. The modeling technique is also known as dynamic phasor modeling. The Type 3 wind generator has become the most popular type of wind generator, making it an ideal candidate for such a modeling method to be developed. The dynamic phasor model provides a generic model and achieves a middle ground between the conventional electromechanical models and the cumbersome…
Domain-Specific Language Model Pre-Training for Korean Tax Law Classification

Owing to their increasing amendments and complexity, most taxpayers do not have the required knowledge of tax laws, which results in issues in everyday life. To use tax counseling services through the internet, a person must first select a category of tax laws corresponding to their tax question. However, a layperson without prior knowledge of tax laws may not know which category to select in the first place. Therefore, a model capable of automatically classifying the categories of tax laws is needed. Recently, a model using BERT has been frequently used for text classification; however, it is generally used in open-domains, and often experiences a degraded performance due to domain-specific technical terms, such as tax laws. Furthermore, a significant amount of time is required to train the model, since BERT is a large-scale model. To address these issues, this study proposes Korean tax law-BERT (KTL-BERT) for the automatic classification of categories of tax questions. For the proposed KTL-BERT, a new pre-trained language model was constructed by performing learning from scratch, to which a static masking method was applied based on DistilRoBERTa. Subsequently, the pre-trained language model was fine-tuned to classify five categories of tax law. A total of 327,735 tax law questions were used to verify the performance of the proposed KTL-BERT. The F1-score of the proposed KTL-BERT was approximately 91.06%, which is higher than that of the benchmark models by approximately 1.07%-15.46%, and the training speed was approximately 0.89%-56.07% higher.
BIOACTIVE COMPOUNDS AND ANTIOXIDANT ACTIVITY OF EXTRACTS FROM EDIBLE FLOWERS OF PUNICA GRANATUM AND CITRUS AURANTIUM

Increasing interest in edible flowers referred on their continuously growing consumption. Extracts of bioactive substances by solvents were the most common method for the processed edible flowers. However, most of the reports deal with ethanol or methanol extracts. Information about the bioactive compounds in water and acetone extracts are limited. Moreover, some reports presented values for fresh weight, while bioavaillability of dry extracts and their antioxidant potential were not discussed in details. Therefore, the object of the current study was to evaluate the content of the bioactive compounds and in vitro antioxidant activity of water and acetone extracts obtained from pomegranate (Punica granatum) and orange trees (Citrus aurantium) edible flowers. The commercial available flowers of pomegranate and orange trees were extracted with water and acetone in an ultrasonic bath. The extracts of edible flowers were analyzed for: carbohydrates (sugars and uronic acids), total chlorophylls, total carotenoids, total phenols, total flavonoids, anthocyanidins. Antioxidant activity was evaluated by four reliable methods (2,2-diphenyl-1-picrylhydrazyl DPPH, 2,2'-azino-bis-3-ethylbenzthiazoline-6-sulphonic acid ABTS, ferric reducing antioxidant power FRAP and cupric reducing antioxidant capacity assays CUPRAC). Orange trees (Citrus aurantium) water extract and acetone extracts from pomegranate (Punica granatum) were obtained in the highest yields. Carbohydrates dominated in orange flowers extracts. Sucrose, glucose and fructose were detected in water extracts of edible flowers. Total chlorophylls, carotenoids, flavonoids and anthocyanidins dominated in acetone extracts from pomegranate. However, water extract of pomegranate contained the highest level of total phenolic compounds 230.8 ± 9.5 mg GAE/g extract. Due to the high total phenolic content, the water extracts of pomegranate demonstrated well pronounced antioxidant activity. The acetone and water extracts from pomegranate (Punica granatum) and orange trees (Citrus aurantium) edible flowers were evaluated as sources of antioxidants. The results reveal the potential application of the obtained edible flower extracts as additives in food and cosmetics.
Regression analysis on e-assessment acceptance by lecturers from security perspective

The role of technology in education system has enriched the teaching and learning process, be it from preschool to higher universities education. The development of online education systems such as e-learning and e-assessment provide many advantages to the users especially the flexibility in teaching and learning. The online education system has the capability to improve the quality of delivery education. However, security risks have been the major weakness in the acceptance of technology in education field which limits the user acceptance of the online education system. Even though there are other studies providing solutions for identified security threats in online education usage, there is no particular model which addresses the factors that influences the acceptance of e-assessment system by lecturers from security perspective. The aim of this study is to explore security aspects of e-assessment in regard to the acceptance of technology by lecturers. A conceptual model of secure acceptance of e-assessment is proposed considering both human and perceived security aspects. The data for this study was collected through online survey and paper-based survey. The conceptual model is analyzed using multiple regressions to identify the predictive power between dependent variable and independent variable. The final result of this study demonstrates how security factors influence lecturers’ attitudes towards the acceptance of e-assessment from security perspective with a strong significant contribution to the e-assessment acceptance by lecturers. This study will be useful in providing more insightful understanding regarding the factors that influence the lecturers’ acceptance of e-assessment system from security perspective.
New Congruences and Finite Difference Equations for Generalized Factorial Functions

We use the rationality of the generalized $h^{th}$ convergent functions, $Conv_h(\alpha, R; z)$, to the infinite J-fraction expansions enumerating the generalized factorial product sequences, $p_n(\alpha, R) = R(R+\alpha)\cdots(R+(n-1)\alpha)$, defined in the references to construct new congruences and $h$-order finite difference equations for generalized factorial functions modulo $h \alpha^t$ for any primes or odd integers $h \geq 2$ and integers $0 \leq t \leq h$. Special cases of the results we consider within the article include applications to new congruences and exact formulas for the $\alpha$-factorial functions, $n! _{(\alpha)}$. Applications of the new results we consider within the article include new finite sums for the $\alpha$-factorial functions, restatements of classical necessary and sufficient conditions of the primality of special integer subsequences and tuples, and new finite sums for the single and double factorial functions modulo integers $h \geq 2$.
Evolution of LMC/M33-mass dwarf galaxies in the eagle simulation

We investigate the population of dwarf galaxies with stellar masses similar to the Large Magellanic Cloud (LMC) and M33 in the EAGLE galaxy formation simulation. In the field, galaxies reside in haloes with stellar-to-halo mass ratios of 1.03+0.50−0.31×10−2 (68 per cent confidence level); systems like the LMC, which have an SMC-mass satellite, reside in haloes about 1.3 times more massive, which suggests an LMC halo mass at infall, M200=3.4+1.8−1.2×1011M⊙ (68 per cent confidence level). The colour distribution of dwarfs is bimodal, with the red galaxies (g − r > 0.6) being mostly satellites. The fraction of red LMC-mass dwarfs is 15 per cent for centrals, and for satellites this fraction increases rapidly with host mass: from 10 per cent for satellites of Milky Way (MW)-mass haloes to nearly 90 per cent for satellites of groups and clusters. The quenching timescale, defined as the time after infall when half of the satellites have acquired red colours, decreases with host mass from >5 Gyr for MW-mass hosts to 2.5 Gyr for cluster mass hosts. The satellites of MW-mass haloes have higher star formation rates and bluer colours than field galaxies. This is due to enhanced star formation triggered by gas compression shortly after accretion. Both the LMC and M33 have enhanced recent star formation that could be a manifestation of this process. After infall into their MW-mass hosts, the g − r colours of LMC-mass dwarfs become bluer for the first 2 Gyr, after which they rapidly redden. LMC-mass dwarfs fell into their MW-mass hosts only relatively recently, with more than half having an infall time of less than 3.5 Gyr.
Capacity of sets and Fourier series

Introduction. In 1939 A. Beurling [l](*) proved that if the series Ew(°n2+&n2) converges then the points of divergence of the Fourier series Oo/2+Er^n cos «x+&n sin «x form a set of logarithmic capacity zero. In the same paper, he stated the following result, the proof of which was due to appear, but to our knowledge has not appeared, in the Arkiv for Matematik: if 0<a^l and if the series Ew<I~'(an2+&n2) converges for every e>0, the above Fourier series is summable by Abel's method except in a set whose (3-capacity is zero for every ß > 1 — a. The present paper has its origin in the desire of the authors to find a more direct and simpler proof of Beurling's results and to extend them. In the course of the work, however, some other theorems of independent interest have been established, and are presented here. The paper is divided into four parts. In the first we give in terms of Fourier series a necessary and sufficient condition for a linear set E to be of positive «-capacity. The second is devoted to the proof of the following theorem which includes the results of Beurling already quoted: If 0<a^l and if the series Ew"(an2+&n2) converges, the set of points of divergence of the Fourier series 0o/2+Ei°an cos «x+ô„ sin «x is of (1 —a)-capacity zero if a^l and of logarithmic capacity zero if a = 1. In the third part we prove some theorems on equi-summability and equiconvergence of certain series and certain integrals of the Dini type. In the fourth part we apply the preceding results to some theorems concerning the existence of certain integrals of the Dini type,
Set-Indexed Conditional Empirical and Quantile Processes Based on Dependent Data

We consider a conditional empirical distribution of the form Fn(C? x)=? nt=1? n(Xt? x)I{Yt? C} indexed by C? C, where {(Xt, Yt), t=1, ? , n} are observations from a strictly stationary and strong mixing stochastic process, {? n(Xt? x)} are kernel weights, and C is a class of sets. Under the assumption on the richness of the index class C in terms of metric entropy with bracketing, we have established uniform convergence and asymptotic normality for Fn(·? x). The key result specifies rates of convergences for the modulus of continuity of the conditional empirical process. The results are then applied to derive Bahadur? Kiefer type approximations for a generalized conditional quantile process which, in the case with independent observations, generalizes and improves earlier results. Potential applications in the areas of estimating level sets and testing for unimodality (or multimodality) of conditional distributions are discussed.
Historical review of Zig-Zag theories for multilayered plates and shells

This paper gives a historical review of the theories that have been developed for the analysis of multilayered structures. Attention has been restricted to the so-called Zig-Zag theories, which describe a piecewise continuous displacement field in the plate thickness direction and fulfill interlaminar continuity of transverse stresses at each layer interface. Basically, plate and shell geometries are addressed, even though beams are also considered in some cases. Models in which the number of displacement variables is kept independent of the number of constitutive layers are discussed to the greatest extent. Attention has been restricted to those plate and shell theories which are based on the so-called method of hypotheses or axiomatic approach in which assumptions are introduced for displacements and/or transverse stresses. Mostly, the work published in the English language is reviewed. However, an account of a few articles originally written in Russian is also given. The historical review conducted has led to the following main conclusions. 1! Lekhnitskii ~1935! was the first to propose a Zig-Zag theory, which was obtained by solving an elasticity problem involving a layered beam. 2! Two other different and independent Zig-Zag theories have been singled out. One was developed by Ambartsumian ~1958! , who extended the well-known Reissner-Mindlin theory to layered, anisotropic plates and shells; the other approach was introduced by Reissner ~1984! , who proposed a variational theorem that permits both displacements and transverse stress assumptions. 3 ! On the basis of historical considerations, which are detailed in the paper, it is proposed to refer to these three theories by using the following three names: Lekhnitskii Multilayered Theory, ~LMT! , Ambartsumian Multilayered Theory ~AMT! , and Reissner Multilayered Theory ~RMT! As far as subsequent contributions to these three theories are concerned, it can be remarked that: 4! LMT although very promising, has almost been ignored in the open literature. 5! Dozens of papers have instead been presented which consist of direct applications or particular cases of the original AMT. The contents of the original works have very often been ignored, not recognized, or not mentioned in the large number of articles that were published in journals written in the English language. Such historical unfairness is detailed in Section 3.2. 6! RMT seems to be the most natural and powerful method to analyze multilayered structures. Compared to other theories, the RMT approach has allowed from the beginning development of models which retain the fundamental effect related to transverse normal stresses and strains. This review article cites 138 references. @DOI: 10.1115/1.1557614#
Pengembangan Panduan Market Day bagi Anak SD Sebagai Internalisasi Jiwa Kewirausahaan

Market Day merupakan salah satu program yang digalakkan pemerintah dalam rangka menginternalisasi jiwa-jiwa wirausaha sejak usia dini. Program ini dilakukan agar anak dapat mengimplementasikan secara langsung di lapangan bagaimana proses transaksi jual beli. Pelaksanaan market day dapat digunakan untuk menumbuhkan kreatifitas pada anak, suka berbagi, kemampuan memecahkan masalah, dan memutuskan masalah. Pelaksanaan market day ini sudah dilaksanakan di beberapa sekolah begitu juga di SD Muhammadiyah di Kabupaten Bantul. Dalam pelaksanaannya, market day belum ada panduan yang tertulis dan terstandar meskipun sudah banyak sekolah yang melaksanakan program ini. Di sisi lain, pelaksanaan program ini sangat ditunggu-tunggu oleh peserta didik dikarenakan kegiatan ini merupakan salah satu kegiatan yang menyenangkan. Untuk mewujudkan kualitas pelaksanaan market day yang sama, perlu adanya panduan yang digunakan dalam pelaksanaan dan juga sistem administrasinya. Dari uraian diatas, penelitian ini bertujuan untuk mengembangkan buku panduan yang bisa digunakan dalam pelaksanaan market day. Penelitian ini dilakukan dari bulan Februari 2022 hingga Oktober 2022. Penelitian ini menggunakan metode pengembangan untuk menghasilkan suatu produk dan diuji keefektifan dari produk tersebut. Penelitian yang digunakan dengan pengembangan model ADDIE dengan lima tahapan yaitu need assessment, Design, Development, Implementation, Evaluation. Hasil validasi dari ahli materi, ahli media dan ahli pembelajaran memiliki nilai yang cukup baik (di atas rata-rata). Sehingga, produk pengembangan buku ini bisa dikatakan layak untuk digunakan. Pengembangan buku panduan market day ini dikatakan layak untuk digunakan karena hasil validasi memiliki nilai yang cukup baik.
Meningioma-Related Epilepsy: A Happy Ending?

(1) Background: More than one-third of patients with meningiomas experience at least one seizure during the course of their disease, and in the 20–50% of cases, seizure represents the onset symptom. After surgery, up to 30% of patients continue to have seizures, while others may experience them later; (2) Methods: The study analyzed retrospectively the risk factors for pre-operative seizures in a large cohort of 358 patients who underwent surgery for newly diagnosed brain meningioma; (3) Results: We identified age, peritumor edema, and location as risk factors for seizure at the onset. Patients with seizures differed from patients without seizures for the following characteristics: younger average age, lower pre-operative Karnofsky Performance Status (KPS), location on the convexity, lower Simpson Grade, lower incidence of pre-operative neurological deficits, and higher incidence of pre-operative peritumor edema. After 24 months, 88.2% of patients were classified as Engel class Ia, and no correlation with disease progression was observed; (4) Conclusions: Meningioma-related epilepsy has generally a positive outcome following surgery and it seems not to be linked to disease progression, even if further studies are needed.
Mass Murder in the United States

Preface. 1. Mass Murder in the United States. 2. History of Mass Murder in the United States. 3. What Is Mass Murder: Theory and Types. 4. The Disciple Mass Killer. 5. The Family Annihilator. 6. The Disgruntled Employee Mass Killer. 7. The Ideological Mass Killer. 8. The Set-and-Run Mass Killer. 9. The Disgruntled Citizen Mass Killer. 10. The Psychotic Mass Killer. 11. Youthful Killers: School Shootings. 12. Problems in Mass Murder Investigation.