Miracle-dz/UniFAR-FTUs huggingface dataset:
Identifying critical capabilities for improving the maturity level of digital services creation process

Purpose: This research aims to develop a digital capability maturity model to find the critical capability and define the maturity level of the digital services creation process for the Business Process Outsourcing (BPO) company, which services cover the end-to-end client’s non-core activities involving people, process, and technology.Design/methodology/approach: The study conducts qualitative approaches in variables selection using grounded theory, followed by in-depth interviews and focus group discussion confirming the chosen variables as relevant capabilities. Additionally, quantitative approaches are used to define the impact of those capabilities on the process through an online survey of 208 employees and Structural Equation Modelling (SEM) for model analysis.Findings: The research proves that alignment strategy has a positive impact on the organizational and individual capabilities, both of which have a positive impact on the process. All capabilities are defined in the “quantitatively managed” maturity level, while the collaboration culture and value creation skill indicators are required to be prioritized in development for having a significant driver yet an inferior performance.Practical implications: The proposed model is built to be generally utilized to help the BPO companies understand their critical capabilities and improve their maturity level to lead the industry. The research contribution is not only to develop a model that is suitable for a particular business but also to create more value for academic purposes through improving the model by introducing a new variable "alignment strategy" and “organizational capability” as an essential component influencing the process.Originality/value: This is a multimethod study that elaborates empirical evidence, literature review, and professional judgment to assess the capabilities of the digital services creation process, to prove the importance of alignment between those capabilities, and to define the process maturity level.
Propagation of p-polarized electromagnetic waves obliquely incident on stratified random media: Random phase approximation

We consider the propagation of p-polarized electromagnetic waves obliquely incident on stratified random dielectric media. Using the invariant imbedding method generalized to random media and applying the random phase approximation, we derive a simple analytical expression of the localization length and calculate the disorder-averaged reflectance and transmittance and the fluctuations of the localization length and the reflectance as functions of the incident angle. We also calculate the disorder-averaged intensity profile of the magnetic field inside the random medium. We find that within the random phase approximation, the p wave can be delocalized and transmitted completely at a certain critical incident angle, which is bigger than the Brewster angle in the uniform case.
Critical points of the area functional of a complex closed curve on the manifold of Kähler metrics

We consider a compact complex manifold M of dimension n that admits Kahler metrics and we assume that C → M is a closed complex curve. We denote by KC(1) the space of classes of Kahler forms [ω] E H 1,1 (M,R) that define Kahler metrics of volume 1 on M and define A C : KC(1) → R by A C ([ω]) = ∫ C w = area of C in the induced metric by ω. We show how the Riemann-Hodge bilinear relations imply that any critical point of A C is the strict global minimum and we give conditions under which there is such a critical point [ω]: A positive multiple of [ω] n-1 ∈ H 2n-2 (M,R) is the Poincare dual of the homology class of C. Applying this to the Abel-Jacobi map of a curve into its Jacobian, C → J(C), we obtain that the Theta metric minimizes the area of C within all Kahler metrics of volume 1 on J(C).
ROC-Analysis Derived Immunohistochemical P53 Cut-Off Scores as an Adjunct to Routine Histopathology for Better Diagnostic Compartmentalisation of Cervical Lesions

Objective The aim of this study was to evaluate the predictive value of Immunohistochemical p53 cut-off scores as an adjunct to routine histopathology for better diagnosis of cervical lesions. Materials and Methods Prospective study carried out for 1 year. After ethical approval and informed consent, a total of 100 cervical tissue samples were analyzed; chronic cervicitis (CC)-15, cervical intraepithelial neoplasia (CIN)-40, and squamous cell carcinoma cervix (SCC)-45 (FIGO 2018 clinical staging). After routine processing of tissue specimen, hematoxylin and eosin (HE) staining was done. Grading of cervical precancerous lesions (CIN) was done as per World Health Organisation criteria as CIN 1,2 or 3. Broder’s grading was assigned for every SCC sample. Results Mean p53 scores of CC, CIN, and SCC cases were 0.0, 1.70, and 4.38, respectively, CIN 1, 2, and 3 were 1.07, 1.63, and 2.22, respectively. SCC was differentiated from CIN3 with p53 ≥4.5 as predictor for SCC, sensitivity and specificity were 57.8% and 88.9%, respectively. Overall diagnostic accuracy of the proposed scoring system for differentiating CC, CIN, and SCC was 61%, while the accuracy of previous methods of interpreting p53 immunoreactivity as immunoscore >2 or arbitrary cut-off of >10% cells with nuclear positivity was only 48%. Conclusion ROC-derived immunoscore cut-offs can provide the much-needed objectivity and optimal decision thresholds to immunohistochemistry interpretation.
Vertical-Plane Dual-Doppler Radar Observations of Cumulus Toroidal Circulations

AbstractHigh-resolution vertical-plane dual-Doppler velocity data, collected by an airborne profiling cloud radar in transects across nonprecipitating orographic cumulus clouds, are used to examine vortical circulations near cloud top. These vortices are part of a toroidal ring centered at an updraft, usually near the cloud top, and they are essential to cumulus entrainment and dynamics. A large number of transects across toroidal circulations are composited to reveal the typical kinematic structure and associated entrainment patterns. The toroidal ring circulation is ~1 km wide and about half as deep in the sampled clouds (Cu mediocris). The composite flow field shows two nearly symmetric, counterrotating vortices, with a core updraft of ~3 m s−1, consistent vortex-top divergence, two flanking downdrafts of the about same strength, and horizontal (toroidal) vorticity of ~0.03 s−1. Variations with vortex size, age, and ambient shear are examined, and the relative dilution of air in the vortex core is esti.
Integration theory for infinite dimensional volatility modulated Volterra processes

We treat a stochastic integration theory for a class of Hilbert-valued, volatility-modulated, conditionally Gaussian Volterra processes. We apply techniques from Malliavin calculus to define this stochastic integration as a sum of a Skorohod integral, where the integrand is obtained by applying an operator to the original integrand, and a correction term involving the Malliavin derivative of the same altered integrand, integrated against the Lebesgue measure. The resulting integral satisfies many of the expected properties of a stochastic integral, including an It\^{o} formula. Moreover, we derive an alternative definition using a random-field approach and relate both concepts. We present examples related to fundamental solutions to partial differential equations.
Humans after Smallpox Vaccination Cutting Edge: Long-Term B Cell Memory in

Memory B cells are a central component of humoral immunity, and yet little is known about their longevity in humans. Immune memory after smallpox vaccination (DryVax) is a valuable benchmark for understanding the longevity of B cell memory in the absence of re-exposure to Ag. In this study, we demonstrate that smallpox vaccine-specific memory B cells last for > 50 years in immunized individuals. Virus-specific memory B cells initially de-clined postimmunization, but then reached a plateau (cid:1) 10-fold lower than peak and were stably maintained for > 50 years after vaccination at a frequency of (cid:1) 0.1% of total circulating IgG (cid:1) B cells. These persisting memory B cells were functional and able to mount a robust anamnestic Ab response upon revaccination. Additionally, vi-rus-specific CD4 (cid:1) T cells were detected decades after vaccination. These data show that immunological memory to DryVax vaccine is long-lived and may contribute to protection against smallpox. The Journal of Immunology, 2003, 171: 4969–4973.
Effective Height Upper Bounds on Algebraic Tori

The main emphasis will be on height upper bounds in the algebraic torus G^{n}_{m}. By height we will mean the absolute logarithmic Weil height. Section 3.2 contains a precise definition of this and other more general height functions. The first appendix gives a short overview of known results in the abelian case. The second appendix contains a few height bounds in Shimura varieties.
Numerical comparison of robustness of some reduction methods in rough grids

In this article, we present three nonsymmetric mixed hybrid RT 1 2 methods and compare with some recently developed reduction methods which are suitable for the single‐phase Darcy flow problem with full anisotropic and highly heterogeneous permeability on general quadrilateral grids. The methods reviewed are multipoint flux approximation (MPFA), multipoint flux mixed finite element method, mixed‐finite element with broken RT 1 2 method, MPFA‐type mimetic finite difference method, and symmetric mixed‐hybrid finite element method. The numerical experiments of these methods on different distorted meshes are compared, as well as their differences in performance of fluxes are discussed. © 2014 Wiley Periodicals, Inc. Numer Methods Partial Differential Eq 30: 1484–1506, 2014
Suppression of Winding AC Copper Loss in High-Speed Electrical Machines by a Practical Transposition Technique

The ac copper loss, which results from the skin effect, the proximity effect, and the bundle-level circulating current, is widely concerned in high-speed electrical machines since they grow rapidly with the frequency. While the skin effect can be easily suppressed by the utilization of thinner wires, the circulating current is generally restrained by a complicated transposition technique. Moreover, the transposition technique is better suited to the preformed winding other than the random-wound winding, hence, it is still difficult to suppress the circulating current ac loss in the random-wound winding. In this article, a practical transposition technique is proposed for the circulating current loss suppression for high-speed electrical machines with random-wound windings. To implement this technique, a specific winding former is designed and manufactured. The proposed transposition technique is verified in a 200 kW, 54 000 r/min high-speed permanent magnet machine, contributing to a reduction of 55.2% copper loss compared to the untransposed winding. The experiment result indicates that the proposed transposition technique is practical in engineering.
Morphological Alteration and Intracellular ROS Generation Confirm Apoptosis Induction on EAC Cells by Leucas Indica Bark Extract

ABSTRACT The phytochemical constituents, antioxidant, cytotoxicity and anti-cancer activities of Leucas indica bark extract in methanol were evaluated. Brine shrimp lethality assay was used to assess the cytotoxicity while antioxidant capability was determined by DPPH and H2O2 free radical scavenging assay. Cell growth inhibition was estimated through hemocytometric cell counting after 5 d of treatment using EAC cells in in vivo mice model. This inhibition was due to the induction of apoptosis observed through fluorescence microscopy. The extract showed anticancer activity against EAC cells with 58.27% cell growth inhibition at 100 mg kg−1 b.w. Morphological alterations identified demonstrated apoptosis induction supported by intracellular ROS generation and DNA fragmentation.
XTE J1908+094

Goddard Space Flight Center reports the serendipitous discovery of a new x-ray transient, XTE J1908+094, in RXTE (Rossi X-ray Timing Explorer) PCA (Proportional Counter Array) observations of the soft-gamma-ray repeater SGR 1900+14, triggered following the burst activity on Feb. 17-18 (GCN 1253). These observations failed to detect the 5.2-s SGR pulsations, pointing towards a possible new source as the origin of the high x-ray flux. An RXTE PCA scan of the region around SGR 1900+14 on Feb. 21 was consistent with emission only from known sources (and no new sources). However, the scans required SGR 1900+14 to be 20 times brighter than its quiescent flux level (GCN 1256). A Director's Discretionary Time Chandra observation on Mar. 11 showed that the SGR was quiescent and did not reveal any new source within the Chandra ACIS (Advanced CCD (charge coupled device) Imaging Spectrometer) field-of-view. A subsequent RXTE PCA scan on Mar. 17, taken in combination with the first scan, required that a new source be included in the fit. The best-fit position is R.A. 19h 08m 50s, Decl. = +9 22 deg . 5 (equinox J2000.0; estimated 2 deg systematic error radius), or approximately 24 deg away from the SGR source. The source spectrum (2-30 kev) can be best fit with a power-law function including photoelectric absorption (column density N_h = 2.3 x 10(exp 22), photon index = 1.55). Iron line emission is present, but may be due to the Galactic ridge. Between Feb. 19 and Mar. 17, the source flux (2-10 keV) has risen from 26 to 64 mCrab. The power spectrum is flat between 1 mHz and 0.1 Hz, falling approximately as 1/f**0.5 up to 1 Hz. At 1 Hz is seen a broad quasiperiodic oscillation peak and a break to a 1/f**2 power law, which continues to 4 Hz. The fractional rms (root mean square) amplitude from 1 mHz to 4 Hz is 43 percent. No coherent pulsations are seen between 0.001 and 1024 Hz. The authors conclude that XTE J1908+094 is a new blackhole candidate.
Efecto de un programa de ejercicio físico sobre la respuesta a proteínas mal plegadas en las células mononucleares de la sangre periférica de pacientes pediátricos con obesidad

La prevalencia de la obesidad infantil ha aumentado a nivel global de forma preocupante, especialmente por las consecuencias que se pueden manifestar en la edad adulta. Se ha demostrado que esta afección aumenta el estrés de retículo endoplásmico(ERE) y, por lo tanto, activa la respuesta a proteínas mal plegadas (UPR). El ejercicio físico es una de las principales propuestas para atajar este reto de salud pública y, específicamente, para resolver el ERE. Por consiguiente, el objetivo de este estudio fue la evaluación del efecto de un programa de entrenamiento combinado de fuerza y resistencia de 12 semanas sobre la UPR en células mononucleares de la sangre periférica (PBMC) de pacientes pediátricos obesos. Para ello, se distribuyeron aleatoriamente 12 niños obesos (9 – 11 años) en un grupo entrenado (GE, n =8), que se sometió al protocolo de entrenamiento, y un grupo control (GC, n = 4), que mantuvo sus rutinas habituales. Se analizaron proteínas de la UPR (ATF4, ATF6 p50, BiP, CHOP, p-eIF2α, p-IRE1 y XBP1s) por Western Blot antes y después del periodo de entrenamiento. Los resultados demostraron que el entrenamiento atenuó el aumento en la fosforilación de eIF2α e IRE1 en comparación con el GC. Además, se observó un efecto tiempo x grupo en la expresión de CHOP tras el entrenamiento. Sin embargo, no se encontraron diferencias en la expresión de ATF4, ATF6 p50, BiPo XBP1 tras el periodo de entrenamiento. En conclusión, los resultados sugieren que el programa de entrenamiento promueve un alivio en el ERE de los pacientes pediátricos obesos. No obstante, se necesitan nuevas investigaciones para determinar la eficacia de programas de entrenamiento alternativos
Association between Guillain-Barré syndrome and Herpes virus family members, A Multiplex PCR study

*Corresponding Author: Sara Lotfy Asser Microbiology and Immunology Department, Faculty of Medicine, Alexandria University Tel. : 01222942970 sara.asar@alexmed.edu. eg Background: Guillain-Barré syndrome is a serious autoimmune peripheral neuropathy, in which the immune system attacks healthy nerve cells. The reason for this condition is unknown; however it is usually triggered by an associated infection, gastrointestinal or a respiratory, and to a less extent vaccination. Several infections have been encountered preceding Guillain-Barré syndrome: Campylobacter jejuni, Influenza, Cytomegalovirus, Epstein-Barr virus, Mycoplasma pneumonia and HIV. Objectives: The aim of this research is to evaluate the etiological correlation between CMV, EBV & HHV-6 infection and Guillain Barre syndrome. Methodology: Peripheral blood samples were collected from 30 patients attending the clinic of Neurology Department, as well as 20 control subjects, to identify the presence of the CMV, EBV & HHV-6 viral genome by Real-time multiplex RCR. Results and Conclusion: This study revealed that CMV UL 32 gene was significantly higher among studied cases as compared to controls and thus may be an attributable etiological agent for triggering the disease.
Slower maximal walking speed is associated with poorer global cognitive function among older adults residing in China

Background Maintaining both walking speed and cognitive function is essential for active, healthy aging. This study investigated age-related differences in walking speed and global cognitive function with aging and the association between them among older adults residing in the developing country of China. Methods This cross-sectional study measured usual (UWS) and maximal walking speed (MWS) of participants for six meters. The Chinese version of the Montreal Cognitive Assessment was used to evaluate global cognition through in-person interviews. Analyses of variance were used to compare the differences in UWS, MWS, and global cognition between genders and age groups. Multiple linear regression models were used to determine the association between walking speed and global cognitive function. Results In total, 791 Chinese adults (252 men and 539 women) aged 60–89 years were included in this study. Markedly slowed UWS and worse global cognitive function scores were observed for both genders among adults ≥80 years of age. MWS slowed considerably in men ≥85 years of age and in women ≥80 years of age. There was a significant gender difference in MWS—with men walking faster than women—but not in UWS. Linear regression analysis adjusted for the confounding factors of gender, height, weight, years of education, and chronic disease indicated that MWS, but not UWS, was significantly associated with global cognitive function (β = 0.086, [0.177, 1.657], P = 0.015) such that slower maximal walking speed was associated with poorer cognitive performance. This association was statistically significant only for adults aged 75-79 years (β = 0.261 [0.647, 4.592], P = 0.010). Conclusion Walking speed was slower in the older age groups. Global cognitive function deteriorated markedly after 80 years of age. After controlling for confounding variables, slower MWS, but not UWS, was associated with poorer global cognitive function. MWS may serve as a potential indicator for earlier identification of poor cognition and motoric cognitive risk syndrome in an older Chinese population.
Industrial Impact On Selected Heavy Metals In Soils Of Nnewi-North Local Government Area, Anambra State, Southeast Nigeria

- The impact of industries on selected heavy metals in soil samples of Nnewi-North, Anambra State, Nigeria was studied. The levels of seven heavy metals (Pb, Mn, Zn, Ni, Cr, Cu, and Cd) in top soil (15-20cm), from the area were determined using Flame Atomic Absorption Spectrophotometric technique. The HNO 3 -HCl-H 2 O 2 method was used in the soil sample extraction. Accuracy of the method was assessed by the determination of a certified reference soil material, CC-141, obtained from European Commission, Joint Research Centre (JRC) Belgium and the results showed agreement with certified values. The soil pH varied from moderately acidic to neutral (6.00-7.11) from the various locations and these are considered as normal for agricultural production. The mean and range concentrations (µg/g), respectively of metals in the soils of the studied area were 38.30±5.54, 13.33-91.67 for Pb, 101.07±16.18, 25.93-190.93 for Mn, 44.04±15.96, 7.33-137.17 for Zn, 2.22±0.50, 0.27-8.60 for Ni, 21.69±8.93,
SYNCHROTRON AND COMPTON SPECTRA FROM A STEADY-STATE ELECTRON DISTRIBUTION

Energy densities of relativistic electrons and protons in extended galactic and intracluster regions are commonly determined from spectral radio and (rarely) γ-ray measurements. The time-independent particle spectral density distributions are commonly assumed to have a power-law (PL) form over the relevant energy range. A theoretical relation between energy densities of electrons and protons is usually adopted, and energy equipartition is invoked to determine the mean magnetic field strength in the emitting region. We show that for typical conditions, in both star-forming and starburst (SB) galaxies, these estimates need to be scaled down substantially due to significant energy losses that (effectively) flatten the electron spectral density distribution, resulting in a much lower energy density than deduced when the distribution is assumed to have a PL form. The steady-state electron distribution in the nuclear regions of SB galaxies is calculated by accounting for Coulomb, bremsstrahlung, Compton, and synchrotron losses; the corresponding emission spectra of the latter two processes are calculated and compared to the respective PL spectra. We also determine the proton steady-state distribution by taking into account Coulomb and π production losses, and briefly discuss implications of our steady-state particle spectra for estimates of proton energy densities and magnetic fields.
Logic, Meaning, and Computation: Essays in Memory of Alonzo Church

Preface C.A. Anderson, M. Zeleny. Remembering Alonzo Church D. Kaplan, T. Burge. Part I: Logic. Logic, truth and number: The elementary genesis of arithmetic P. Apostoli. Second-order logic J. Corcoran. A representation of relation algebras using Routley-Meyer frames J.M. Dunn. Church's set theory with a universal set Th. Forster. Axioms of infinity in Church's type theory R.O. Gandy. Logical objects E.L. Keenan. The lambda calculus and adjoint functors S.M. Lane. Atomic Boolean algebras and classical propositional logic G.J. Massey. Improved decision procedures for pure relevant logic R.K. Meyer. The 'triumph' of first-order languages S. Shapiro. Equivalence relations and groups R. Smullyan. Part II: Computation. Discriminating coded lambda terms H. Barendregt. lambda-calculus as a foundation for mathematics K. Grue. Peano's lambda calculus: The functional abstraction implicit in arithmetic D. Leivant. The undecidability of lambda-definability R. Loader. A construction of the provable wellorderings of the theory of species P. Martin-Lof. Semantics for first and higher order realizability C. Mclarty. Language and equality theory in logic programming J.C. Shepherdson. Part III: Philosophy, Meaning, and Intensional Logic. Alternative (1*): A criterion of identity for intensional entities C.A. Anderson. Nominalist paraphrase and ontological commitment J.P. Burgess. Peace, justice and computation: Leibniz' program and the moral and political significance of Church's theorem M. Detlefsen. Tarski's theorem and NFU M.R. Holmes. Church's theorem and randomness G. Mar. Russellian type theory andsemantical paradoxes E. Martino. The logic of sense and denotation: Extensions and applications T. Parsons. Analysis, synonymy and sense M. Richard. The very possibility of language N. Salmon. Index.