Miracle-dz/UniFAR-FTUs huggingface dataset:
MINIREVIEW Nonsegmented Negative-Strand Viruses as Vaccine Vectors

The live-virus vector era began in 1983, when Smith, Mack-ett, and Moss constructed a recombinant vaccinia virus expressing hepatitis B surface antigen and demonstrated the induction of hepatitis B-speciﬁc antibodies in rabbits immunized with the recombinant virus (113). Subsequently, live-virus vectors were developed with other DNA viruses, such as adeno-viruses and herpesviruses, and with positive-strand RNA viruses, such as alphaviruses and ﬂaviviruses. The vaccine vector potential of the large group of nonsegmented negative-strand RNA viruses (NNSV) remained unexplored largely due to the lack of infectivity of their genomic RNA in cell culture and the absence of a mechanism for recombinational insertion of foreign genes. The NNSV (order Mononegavirales ) comprise four families: Rhabdoviridae , represented by vesicular stomatitis virus (VSV) and rabies virus (RV); Paramyxoviridae , including Sendai virus (SeV), human parainﬂuenza virus types 1, 2, 3, and 4 (HPIV1 to -4), measles and mumps viruses, Newcastle disease virus (NDV), and human respiratory syncytial and metapneumoviruses (HRSV and HMPV); Filoviridae , containing Ebola and Marburg viruses; and Bornaviridae , containing Borna disease virus. In 1994, Schnell, Mebatsion, and Conzel-mann developed a reverse genetic system for RV that
Sasakian Exact Solutions for Spinning Black Holes in Superstring Inspired Gravities

In this thesis, we study the gravitational solution with Sasakian structure and its novel relation to higher-dimensional black hole physics. As long as superstring theory is valid in some sense, higher-dimensional spacetime is a necessity framework. Therefore, we need to study higher-dimensional gravitational theories, which may result in its low-energy limit. We have successfully found new solutions in two supergravity (SUGRA) theories. First, in the 5-dimensional gauged minimal SUGRA, we have obtained a new (reduced) solution, which corresponds to a nontrivial limit of a known charged rotating black hole. Although this solution violates the Sasakian condition slightly, we have used this as means of extending the Sasakian condition in any odd-dimensional spacetime; it may be used as a guiding principle for finding other reduced solutions whose original black hole has not been found yet. This results in allowing the presence of torsion, which deforms the original Sasakian condition. Applying this modification, we have found a new solution in the 11-dimensional SUGRA. We have also obtained new exact solution in Einstein–Gauss–Bonnet gravity in every odd dimensions higher than 3, using the highly isometric ansatz that admits Sasakian structure. These solutions are novel in the sense that (i) their angular momentum is finite (they are rotating), (ii) they are asymptotically AdS at least locally, (iii) they couple to the Maxwell-field (they are charged). In regard to (i), we note that this is the very first case of successful evaluation of conserved charges (angular momentum and energy), made possible by the detail study of the Abbott-Deser formulation. We have clarified the difference of our solutions from other known solutions: some of the 2-rotating solution with zero angular momentum can be reproduced as a special case of our solution, and some of the topological static black holes are also obtained similarly.
The Complete Musician: An Integrated Approach to Tonal Theory, Analysis, and Listening

Sat, 08 Dec 2018 02:44:00 GMT the complete musician an integrated pdf The Complete Musician. An Integrated Approach to Theory, Analysis, and Listening. Fourth Edition. Steven G. Laitz. Publication Date November 2015. ISBN: 9780199347094 Sun, 25 Nov 2018 13:37:00 GMT The Complete Musician Paperback Steven G. Laitz . The Complete MusicianAn Integrated Approach to Tonal Theory, . (chapters 1 15). pdf. Heinrich Schenker . Documents Similar To The Complete Musician_laitz. Kent . Fri, 07 Dec 2018 18:30:00 GMT The Complete Musician_laitz Scribd The Complete Musician: An Integrated Approach to Tonal Theory, Analysis, and Listening. By Steven G. Laitz. pp. xxiv + 888; CD. (Oxford University Press, New York and . Fri, 07 Dec 2018 02:53:00 GMT Project MUSE The Complete Musician: An Integrated . The Complete MusicianAn Integrated Approach to Tonal Theory, Analysis & Listening Ebook download as PDF File (.pdf) or read book online. The Complete MusicianAn . Wed, 08 Jun 2011 23:58:00 GMT The Complete MusicianAn Integrated Approach to Tonal . Download the Book:The Complete Musician: An Integrated Approach To Tonal Theory Analysis And Listening 3rd Edition PDF For Free, Preface: Fri, 07 Dec 2018 16:43:00 GMT The Complete Musician PDF bookslibland.net The Complete Musician has 46 ratings and 1 review. Richard said: Absolutely exhaustive work on the common music practice. if you are an aspiring compos. Sun, 11 Nov 2018 02:05:00 GMT The Complete Musician: An Integrated Approach to Tonal . The Complete Musician: An Integrated Approach to Theory, Analysis, and Listening [Steven G. Laitz] on Amazon.com. *FREE* shipping on qualifying offers. The Complete . Sat, 17 Nov 2018 07:41:00 GMT The Complete Musician: An Integrated Approach to Theory . Bringing together the analytical, aural, and tactile activities that comprise a tonal theory curriculum, The Complete Musician, Second Edition, relies on a diverse . Tue, 04 Dec 2018 10:34:00 GMT The Complete Musician: An Integrated Approach to Tonal . The Complete Musician: An Integrated Approach To Theory, Analysis, And Listening PDF Thu, 11 Oct 2018 21:25:00 GMT The Complete Musician: An Integrated Approach To Theory . The Complete MusicianAn Integrated Approach to Tonal . (chapters 1 15). pdf. Kostka Tonal Harmony 8th . Documentos similares a The Complete Musician_laitz. Fri, 30 Nov 2018 16:08:00 GMT The Complete Musician_laitz Scribd Find helpful customer reviews and review ratings for The Complete Musician: An Integrated Approach to Theory, Analysis, and Listening at Amazon.com. Read honest and . Sun, 25 Nov 2018 09:19:00 GMT Amazon.com: Customer reviews: The Complete Musician: An . Read Now http://readsbookonline.com. playsterbooks.com/? book=
The Impact of ART on the Fertility of HIV-Positive Women in Sub-Saharan Africa: A Systematic Review

Objective: Understanding the fertility of HIV-positive women is critical to estimating HIV epidemic trends from surveillance data and planning resource needs and coverage of prevention-of-mother-to-child transmission services in sub-Saharan Africa. In light of the considerable scale-up in antiretroviral therapy (ART) coverage over the last decade, we conducted a systematic review of the impact of ART on the fertility outcomes of HIV-positive women. Methods : We searched Medline, Embase, Popline, PubMed and African Index Medicus. Studies were included if they were conducted in sub-Saharan Africa and provided estimates of fertility outcomes (live births or pregnancies) among women on ART relative to a comparison group. Results: Of 2070 unique references, 18 published papers met all eligibility criteria. Comparisons fell into four categories: fertility of HIV-positive women relative to HIV-negative women; fertility of HIV-positive women on ART compared to those not yet on ART; fertility differences by duration on ART; and temporal trends in fertility among HIV-positive women. Evidence indicates that fertility increases after approximately the first year on ART, and that while the fertility deficit of HIV-positive women is shrinking, their fertility remains below that of HIV-negative women. These findings, however, were based on limited data mostly during the period 2005-2010 when ART scaled-up. Conclusions: Existing data are insufficient to characterize how ART has affected the fertility of HIV-positive women in sub-Saharan Africa. Improving evidence about fertility among women on ART is an urgent priority for planning HIV resource needs and understanding HIV epidemic trends. Alternative data sources such as antenatal clinic data, general population cohorts and population-based surveys can be harnessed to understand the relationship moving forward. ABSTRACT Structured summary 2 Provide a structured summary including, as applicable: background; objectives; data sources; study eligibility criteria, participants, and interventions; study appraisal and synthesis methods; results; limitations; conclusions and implications of key findings; systematic review registration number.
Why Parents Worry

In this paper we use individual level data from the Australian National Drug Strategy Household Survey to study the relationship between initiation into cannabis use and educational attainment. Using instrumental variable estimation and bivariate duration analysis we ﬁnd that those initiating into cannabis use early in life are much more likely to dropout of school compared to those who start later on. Moreover, we ﬁnd that the reduction in years of schooling depends on the age at which initiation occurs, and that it is larger for females than males.
Effect of Technology Performance of Mainstream

Educationist has been showing a keen interest in teaching from the 18 education, a drastic change was seen in educational policies all over the world. The child application technology in classrooms. This randomized posttest control group design Experimental Research explored the cause relationships among variables. A pilot experimental research with sixty (60) participants from Grade IX was conducted at secondary school in Karachi. Thirty students participated in the experimental group and thirty students in the controlled group. Data was collected through the achievement performance of participants after 20 days postto give awareness for using technology as a teaching tool at the secondary school level. Findings of t 0.001) showed that differences in mean of controlled group and experiment group (M= 50.77, 68.17) that performance of students who are Studying in an interactive technology smartphone, internet, SMS, so significantly higher than scores of students who were instructed using conventional lecture effectiveness of teaching using technology secondarylearning is promoted in the public sector secondary schools across the country.
Operational practices of lean manufacturing: Potentiating environmental improvements

Purpose: The objective of this paper is to investigate how environmental improvements can be achieved through operational practices of Lean Manufacturing. Design/methodology/approach: A literature review was conducted to analyze the relationship between operational practices of Lean and reduction of environmental impact in organizational contexts. Verified theoretically, this relationship was observed in a company of the electronics industry, through an exploratory research which contemplated a mixed approach. The adopted research method consisted of a single case study, by providing greater depth and detail of the study. Utilized a research protocol, validated test pilot. The instruments for data collection were semi-structured interviews, direct observation and document analysis. The information was examined qualitatively considering the technique for content analysis. Findings: As a result of the study, it was found that there is evidence for the existence of relationship between the practices of Lean, for example, Kaizen, PDCA (plan, do, check, act), Ishikawa Diagram, Poka-Yoke, Standardized Work and Value Stream Mapping, with the reduction of environmental impacts of an organization. This reduction was observed after application of these practices that resulted in the reduction of energy consumption, water and waste generation. These results were accounted for financially, contributing to a reduction of annual costs by about US$ 20,900. Originality/value: The study presents in detail, the application of operational practices of Lean Manufacturing, with an effective view to reducing the environmental impact and cost reduction. The literature review, a detailed description of the application process and financial results are important information that contributes to the scientific studies that address traditional operating practices and the search for better environmental performance.
Inﬂammatory Undifferentiated Pleomorphic Sarcoma Mimicking Bacteremia in an Elderly Patient: A Case Report

: Undifferentiated pleomorphic sarcoma (UPS) is major type of soft tissue sarcomas. UPS presenting with inﬂammation is rare, and its pathophysiology remains unclear. Herein, we report a rare case of UPS with prolonged fever. A 91-year-old female complaining of high fever was referred to our hospital because of a high C-reactive protein (CRP) level of 12.51 mg/dL. She had been experiencing intermittent fevers for approximately 10 years. The fever of unknown origin worsened with time and went into remission with repeated antimicrobial therapy. She also had a mass on her central lower back over the sacral region for 6 years, which showed a gradual increase in size. The blood tests showed that the leukocyte count and neutrophils were 6.51 × 10 3 / µ L and 70.3%, respectively. She had a 10 × 10 cm mass on her buttock that showed 2-[ﬂuorine-18] ﬂuoro-2-deoxy-d-glucose (FDG) accumulation on FDG-positron emission tomography-computed tomography examination (standardized uptake value-max value: 5.4). A blood culture examination was performed to rule out bacteremia, however, no bacteria were identiﬁed. We then performed a needle biopsy and conﬁrmed the diagnosis of UPS; subsequently, the patient underwent a wide-margin resection. A few days after the surgery, her CRP, leukocyte, and neutrophil levels decreased to 0.305 mg/dL, 2.83 × 10 3 /uL, and 50.1%, respectively. This case demonstrated that UPS with inﬂammation should be treated surgically as soon as possible after ruling out other sources of infection to achieve a favorable prognosis.
Neutrino-electron processes in a dense magnetized plasma

The neutrino-electron scattering in a dense degenerate magnetized plasma under the conditions $\mu^2>2eB \gg \mu E$ is investigated. The volume density of the neutrino energy and momentum losses due to this process are calculated. The results we have obtained demonstrate that plasma in the presence of an external magnetic field is more transparent for neutrino than non-magnetized plasma. It is shown that neutrino scattering under conditions considered does not lead to the neutrino force acting on plasma.
Noncalci ﬁ ed Coronary Atherosclerotic Plaque and Immune Activation in HIV-Infected Women

Background . Little is known about coronary plaque in human immunode ﬁ ciency virus (HIV) – infected women. Methods . Sixty HIV-infected and 30 non – HIV-infected women without symptoms or history of cardiovascular disease were recruited to assess coronary plaque with coronary computed tomographic angiography and immune activation. Data from 102 HIV-infected men and 41 non – HIV-infected male controls were compared. Results . HIV-infected women demonstrated signi ﬁ cantly higher percentages of segments with noncalci ﬁ ed plaque (mean ± SD, 74% ± 28% vs 23% ± 39% compared to female control subjects; median [interquartile range], 75% [63% – 100%] vs 0% [0% – 56%]; P = .007) and more segments with noncalci ﬁ ed plaque (mean ± SD, 0.92 ± 1.48 vs 0.40 ± 1.44; median [interquartile range], 0 [0 – 2] vs 0 [0 – 0]; P = .04). Immune activation parameters, including soluble CD163 (sCD163; P = .006), CXCL10 ( P = .002), and percentages of CD14 + CD16 + monocytes ( P = .008), were higher in HIV-infected women than in female control subjects, but no differences were seen in general in ﬂ ammatory markers. Among HIV-infected women with noncalci ﬁ ed coronary plaque, sCD163 levels were signi ﬁ cantly higher than in HIV-infected women without noncalci ﬁ ed plaque ( P = .04). In multivariate modeling for sCD163 levels among male and female subjects, signi ﬁ cant effects of HIV ( P < .0001), age ( P = .002), and sex ( P = .0002) were seen. Conclusions . Young, asymptomatic, HIV-infected women, demonstrate increased noncalci ﬁ ed coronary plaque and increased immune activation, particularly monocyte activation. Independent effects of sex, HIV status, and aging on immune activation may contribute to cardiovascular disease in this population. Clinical Trials Registration . NCT00455793.
Underwater God Rays from a Custom Volume Renderer

Peanut Butter Jelly, directed by Alexander Beaty, is a 51 second computer–animated short film produced by Digital Production Arts. The plot focuses on a fight sequence between a pirate jelly fish and a flyboy jelly fish over a peanut butter jar. The production demanded a photo–realistic computer generated underwater environment, which lead to the need for a custom built volume renderer to render high quality god rays. This thesis illustrates the requirement for a customized volume renderer for the production, the algorithm, and the implementation of the renderer. It also describes a tool created for Maya 2012 which gives the artist, artistic control to change the render settings.
Clinical and prognostic significance of 3q26.2 and other chromosome 3 abnormalities in chronic myelogenous leukemia in era of tyrosine kinase inhibitors

Chromosome 3q26.2 abnormalities in acute myeloid leukemia (AML), including inv(3)/t(3;3) and t(3;21), have been studied and are associated with a poor prognosis. Their prevalence, response to tyrosine kinase inhibitor (TKI) treatment and prognostic significance in chronic myelogenous leukemia (CML) are largely unknown. In this study we explored these aspects using a cohort of 2013 CML patients in the era of TKI therapy. Chromosome 3 abnormalities were observed in 116 of 2013 (5.8%) cases. These cases were divided into five distinct groups: A, inv(3)(q21q26.2)/t(3;3)(q21;q26.2), 26%; B, t(3;21)(q26.2;q22), 17%; C, other 3q26.2 rearrangements, 7%; D, rearrangements involving chromosome 3 other than 3q26.2 locus, 32%; and E, gain or loss of partial or whole chromosome 3, 18%. In all, 3q26.2 rearrangements were the most common chromosome 3 abnormalities (50%, groups A-C). 3q26.2 rearrangements emerged at different leukemic phases. For cases with 3q26.2 rearrangements that initially emerged in chronic or accelerated phase, they had a high rate of transformation to blast phase. Patients with 3q26.2 abnormalities showed a marginal response to TKIs treatment and no patients achieved a long-term sustainable response at cytogenetic or molecular level. Compared to other chromosomal abnormalities in CML, patients with 3q26.2 rearrangements had a poorer overall survival. The presence or absence of other concurrent chromosomal abnormalities did not affect survival in these patients, reflecting the predominant role of vs E; p=0.69 for C vs E). The median survival time after the emergence of ACAs in groups A-E was 14.3, 13.6, 11.9, 31, and 7.5 months respectively. The overexpression of EVI1 by 3q26.2 rearrangements in clonal evolution in CML offers a BCR-ABL1 independent oncogenic pathway. Studies had shown that the cooperation of BCR-ABL1 and EVI1 signaling can block myeloid differentiation and induce blast crisis 32 . The presence of BCR-ABL1 independent signaling by EVI1 overexpression also explains the resistance of CML to TKIs therapy, which is targeted to BCR-ABL1.
WOOL ANALYSIS AS AN INDICATOR FOR DIAGNOSIS OF SOME TRACE ELEMENTS DEFICIENCY IN SHEEP

The present study aimed to establish the different concentrations of Copper, Zinc, Iron, and Manganese in sheep blood serum, wool and feed stuffs, in comparison with the recorded results obtained from apparently healthy sheep. A total number of 40 ewes 10 of them were apparently healthy and 30 ewes showed different signs as (easly detached wool, anorexia and diarrhoea), their ages ranged between 1-4 years. Blood serum, wool and feed samples of sheep were collected from different villeges around Assiut city. The present study revealed that diseased sheep showed highly significant decrease in the serum and wool Copper, Zinc, Iron, and Manganese levels in comparison with apparently healthy ones. Pearson’s correlation coefficient revealed that Cu, Zn, Fe, and Mn were positively correlated in both blood serum and wool samples. Mean levels of copper, zinc, iron, and manganese in hay and crop residue mixture at the dry matter basis, fall at the lower margin of the latest NRC recommendations. These findings indicated that the concentrations of trace elements in the wool of sheep gave a good indication for the diagnosis of of some trace elements deficiency.
Racine – Construct and convergent validity of CogState in late middle-age

Background : CogState is a computerized cognitive battery spanning domains of memory, executive function, and speed and processing. CogState, designed to be robust to education level and efficient for repeated administration with minimal practice effects, holds potential for detecting early cognitive dysfunction in at-risk populations. This project aimed to provide convergent and construct validity for aspects of the CogState battery in a late-middle-aged cohort enriched for risk factors for Alzheimer’s disease (AD) and to evaluate CogState performance against traditional neuropsychological tests of delayed memory. Methods : 469 late-middle-aged participants from the Wisconsin Registry for Alzheimer’s Prevention (mean age 63.8±7 years at testing; 67% female; 39% APOE4+) completed a traditional paper-based neuropsychological battery and seven tests from the CogState battery approximately ten years post-baseline. A composite cognitive impairment index (CCII) was calculated using eight neuropsychological tests acquired longitudinally and estimated at age 65 to remove confounding effects of age. Early cognitive impairment status (n=70) was determined by consensus case review. A subset underwent cerebrospinal fluid (CSF) collection (n=73) and PET-PiB imaging (n=96). We examined relationships between CogState variables and demographic characteristics; relationships between CogState and scores on traditional paper-based neuropsychological tests as well as a composite cognitive impairment index; group differences between normal and cognitively impaired participants; and associations with previously acquired biomarkers for amyloid and tau (CSF total-tau/A β 42 and global PET-PiB burden) and neural injury (CSF neurofilament light protein). In parallel we examined three traditional tests of delayed memory with demographics, cognitive status, and biomarkers. Results Racine – Construct and convergent validity of CogState in late middle-age the CogState tests employed may have utility as non-circular outcomes, which are less influenced by demographic variability, in longitudinal studies of people at risk for AD.