Miracle-dz/UniFAR-FTUs huggingface dataset:
Sliding Mode Control-Based Decoupling Scheme for Quad-Active Bridge DC–DC Converter

As a multiport DC–DC converter, quad-active bridge (QAB) has been widely used in energy routers, photovoltaic energy systems, and vehicle power supplies because of its advantages of high efficiency and high power density. However, every port of the QAB converter is coupled together through a high-frequency (HF) transformer, which poses a challenge to the controller design. This article proposes a sliding mode controller (SMC)-based decoupling control scheme, which combines input matrix diagonalization and extended state observer (ESO). The input matrix diagonalization realizes most coupling and the SMC realizes the remaining coupling. To effectively reduce the chattering caused by the SMC, the ESO is applied to estimate the total disturbances. Theoretical analysis shows that the proposed decoupling control scheme transforms a multiple input multiple output (MIMO) control system into three independent single-input single-output (SISO) control systems, which realizes independent control of all the port voltages. Besides, experimental results show that the proposed scheme can almost eliminate the coupling relationship between ports, and improve the dynamic response of the system.
Reduction of On-Load DC Winding-Induced Voltage in Partitioned Stator Wound Field Switched Flux Machines by Dual Three-Phase Armature Winding

Voltage induced in the dc winding by the armature field in wound field switched flux (WFSF) machines will induce voltage perturbation in the voltage supply and cause dc winding current ripple and field excitation fluctuation. This will challenge the dc voltage controller and deteriorate the control performance, especially when the load and/or the rotor speed are high. In this article, the dual three-phase armature winding design with a phase-shift of 30 electrical degrees is employed in the partitioned stator WFSF machines to reduce the on-load dc winding-induced voltage. Analytical deductions and finite element (FE) results demonstrate that the dominant sixth-order-induced voltage harmonic can be suppressed to zero. Hence, the peak-to-peak induced voltage in the 12/11- and 12/13-pole partitioned stator WFSF machines can be reduced by 83.35% and 82.53%, respectively. Due to the improvement of winding factors, the torque densities are 4.85% and 5.60% higher, respectively. Prototypes are built and tested to verify the analytical and FE results.
Multi-objective Analysis of Sustainable Generation Expansion Planning based on Renewable Energy Potential: A case study of Bali Province of Indonesia

This article analyzes the role of renewable energy in producing sustainable generation expansion planning. The generation expansion planning is carried out using an optimization model which has two objective functions, namely the objective function of planning costs and the objective function of emissions. Multi-objective analysis was performed using the epsilon constraint method to produce the Pareto set. Solution points are selected from the Pareto set generated using the fuzzy decision making method. The process of determining the best solution points is based on three scenarios. Furthermore, calculations were carried out to obtain 7 indicators of sustainability covering economic, social, and environmental aspects. The sustainability index is calculated based on several predetermined policy options. The model is implemented using data obtained from the electricity system in Bali Province, Indonesia. From the analysis, the planning scenario by implementing renewable energy sources in the generation of electrical energy, namely scenario 3, results in an increase in the sustainability index with the highest value during the planning period. However, scenario 3 produces two sustainability indices from the economic aspect, namely the unit cost of generation and shared electricity cost to GDP, which is the lowest when compared to other scenarios.
Providing nurse supervisors with a theoretical framework to support student learning during placement-based work integrated learning: A survey study

There is an absence of information about the efficacy of teaching techniques specifically used to prepare nurse supervisors in clinical teaching and supervision of students during placement-based work integrated learning (WIL). For nurse supervisors to gain an understanding of the student perspective, participants undertook continuing professional development interactive simulation activities. This pre-post intervention study aimed to determine whether interactive simulation as an intervention was effective for preparing registered nurses (n=60) to support student learning during WIL. Furthermore, the research assessed whether the clinical reasoning cycle became integrated into nurse supervision practices on return to the workplace. There was a significant increase in post-workshop skill ratings compared to pre-workshop for all 19-item scores. At six-weeks follow-up, four items remained stable. For 15 of the 19 items there was a statistically significant downward shift in the spread of the data. However, median skill/knowledge scores were equivalent for 13 items. The findings showed inclusion of the clinical reasoning cycle using the same pedagogical framework students would experience during interactive simulation, improved nurse supervisor’s skills and confidence ratings in the short-term. Further continuing professional development using interactive simulation may advance embedding of the theoretical framework and promote knowledge and skill retention.
In situ second-harmonic generation mediated photodynamic therapy by micelles co-encapsulating coordination nanoparticle and photosensitizer

The indirect excitation of a photosensitizer mediated with nonlinear optical mechanism is a strategy for applying tissue penetration enhanced near infrared (NIR) light on photodynamic therapy (PDT). Herein, we introduced a NIR-PDT strategy that employed a nonlinear optical nano-conveyor named AHU-1 bearing strong second-harmonic generation (SHG) properties. AHU-1 could emit exactly half of the incident wavelengths for indirectly exciting the strong absorption soret band of the photosensitizers. Biocompatible micelles (mPEG–PDLLA) were applied to simultaneously encapsulate AHU-1 and photosensitizer, chlorin e6 (Ce6), for increasing their solubility and stability. The size and morphology of cargo loaded micelles were characterized by DLS and TEM. The cytotoxicity studies, live cell imaging and in situ photodynamic efficacy were conducted on B16 melanoma cells, and the SHG-mediated PDT effectively eliminated the cancer cells. This study provides a novel strategy for the application of nonlinear optical materials in photodynamic therapy.
A Trajectory Evaluation Platform for Urban Air Mobility (UAM)

Nowadays, there is an increase in the demand for optimized services in urban environments. However, ground transportation in big urban centers has been facing challenges for many years (e.g., resilience and congestion) and new paradigms have been proposed, such as the Urban Air Mobility (UAM) concept. UAM aims to enhance the urban transportation system using manned and unmanned aerial vehicles (i.e., Electric Vertical Takeoff and Landing - eVTOL - vehicles). Although UAM offers many benefits (e.g., cost reduction and increase in transportation capacity), many challenges need to be faced to enable safe and efficient operations. Furthermore, trajectory planning is challenging in the National Airspace System (NAS) and UAM operations due to several factors. Finally, new initiatives concerning UAM trajectory planning can be accelerated with the support of an automatic what-if platform capable of evaluating trajectories feasibility and efficiency. This research aims to propose a simulation platform for enabling trajectory evaluation in UAM operations. This platform, named Trajectory-Based Urban Air Mobility Simulator (TUS), focuses on simulating trajectories in the urban aerial environment. TUS enables users to test new UAM algorithms (e.g., flow management strategies, real-time evaluation of maneuvers effectiveness, airspace configurations) and simulate both manned and unmanned vehicles. Furthermore, TUS operation relies on a set of inputs and evaluates the trajectories generated from efficiency and safety perspectives. This process is performed using a Discrete Event Simulation (DES) approach. The experiments performed showed that TUS can perform a realistic evaluation of UAM trajectories and can be effortlessly used to simulate hundreds of scenarios.
RECORDS OF PHARMACEUTICAL AND BIOMEDICAL SCIENCES Anti-Diabetic Medications: A promising therapeutic approaches for the Management of NAFLD

Type 2 diabetes and Nonalcoholic fatty liver disease are two of the most common metabolic diseases in the world, with an increasing prevalence. Patients with T2DM have a two-fold increased risk of developing NAFLD, The evidence that certain antidiabetic drugs boost NAFLD/NASH in T2DM patients is growing. However, there are no specific pharmacologic treatments available. This review aims to outline the data supporting the effectiveness of anti-diabetic drugs in the treatment of NAFLD, besides providing an overview of novel antidiabetic therapies that have been proposed to achieve this goal. Most of these anti-diabetic agents demonstrate short-term efficacy, but have shown little to no impact on hepatic histology. Only thiazolides and GLP-1 receptor agonists have shown considerable improvement in hepatic histology.
Dietary salt regulates ubiquitination and urinary excretion of Na-Cl cotransporter

Background: Membranous localization of NCC is mandatory for its function at distal convoluted tubule. Post-translational modification like phosphorylation and ubiquitination are important for various membrane proteins for their membranous localization. It has previously been reported that phosphorylation of NCC increased its membranous localization. We previously reported, low salt diet increased and high salt diet decreased expression and phosphorylation of NCC in kidney. Objectives: In this study, we investigated whether ubiquitination is involved in the mechanisms of NCC regulation by dietary salt. Materials & Methods: We examined ubiquitination and urinary excretion of NCC from mice fed with low-, regularand high-salt diet. Study was done at Tokyo Medical and Dental University,during the period of January, 2013 to March, 2013. Results: We found that, high salt diet increased and low salt diet decreased ubiquitination of NCC, correlated well with their total NCC abundance in kidney. Urinary excretion of exosomal NCC was increased both under low and high salt diet. Conclusion: These results clearly indicated that dietary salt regulates ubiquitination of Na-Cl cotransporter and its urinary excretion.
The Municipal Audit Committee Self-review Threat: The South African Dilemma

Context: Corporate governance in South African municipalities is severely lacking and retrograding. The audit committee should essentially be an oversight committee that acts on behalf of the municipal council to ensure that key controls are operating, ethical practices are reinforced, key accounting estimates and judgements are properly made, and that internal and external audits are effective. However, the Municipal Finance Management Act requires that the audit committee acts in an advisory capacity to among others, the municipal management. This statutory requirement is in contrast to international governance code best practice for audit committees. Purpose: The aim of this study was to establish how municipal audit committee members perceive their role and whether they realise the self-review threat brought about by the role conflict between legislation and internationally accepted best practice. Design: A web-based survey questionnaire was used to collect primary data from municipal audit committee members. Findings: The study found that municipal audit committee members seem to be unaware of the self-review threat their perspectives on their role hold. Practical implications: Results of the study may assist policy makers and other stakeholders in drafting regulations and legislation governing the functioning and establishment of independent municipal audit committees in South Africa. Originality: Although the conflicting roles of assurance (oversight) and consulting (advisory) have received attention in the disciplines of external auditing and internal auditing, similar attention is needed in the case of South African municipal audit committees.
Psychosocial Rehabilitation Interventions in the Treatment of Schizophrenia and Bipolar Disorder

Schizophrenia and bipolar disorder are chronic conditions with the early onset, higher relapse rate, and functional impairment that often persist despite optimum pharmacotherapy, underscoring the need for adjunctive psychosocial treatments and rehabilitation interventions. Evidence-based psychosocial treatment and rehabilitation interventions for both illnesses are adherence therapy, psychoeducation, cognitive-behavioral therapy, interpersonal and social rhythm therapy, cognitive remediation, social skills training, family education, vocational rehabilitation, case management, assertive community treatment, occupational/art therapy, and peer support. The efficacy of these interventions has been shown in many studies. Trials generally reveal that symptom reductions, relapse preventions, reduced hospitalizations, increased social functioning, increased employment rate, and satisfactory quality of life for patients with schizophrenia and bipolar disorder are possible by using these interventions adding to optimal pharmacotherapy. This review describes the psychosocial rehabilitation interventions that have been used successfully and extensively in patients with schizophrenia and bipolar disorder.
Theoretical Study of the Chemical Reactivity of Five Schiff Bases Derived From Dapsone by the DFT Method

This theoretical study of chemical reactivity was conducted using the method of the Density Functional Theory (DFT), with B3LYP/6-311G (d, p) as calculation level. A series of five (05) Schiff bases derived from 4.4 '-diaminodiphenylsulfone (Dapsone) was concerned and allowed to predict the chemical reactivity of these compounds. Molecular geometries and electronic properties such as the energies of the frontier molecular orbitals (HOMO and LUMO), ionization potential (I), and Review Article N’dri et al.; CSIJ, 22(4): 1-11, 2018; Article no.CSIJ. 41427 2 electron affinity (A) were examined to obtain a better overview of the molecular properties. Thus compound 4, whose energy gap between the frontier orbitals (HOMO and LUMO) is ΔEgap = 3.910 eV appears to be the most polarizable. It is the most reactive with the lowest kinetic stability compared to all the studied molecules. The values of the global reactivity descriptors confirmed the great chemical reactivity of the compound 4. Local indices of reactivity and dual descriptors were calculated to indicate the probable sites of Electrophilic and nucleophilic attacks of the various studied compounds.
Modeling the sensitivity of hydrogeological parameters associated with leaching of uranium transport in an unsaturated porous medium

The uranium ore residues from the legacies of past uranium mining and milling activities that resulted from the less stringent environmental standards along with the uranium residues from the existing nuclear power plants continue to be a cause of concern as the final uranium residues are not made safe from radiological and general safety point of view. The deposition of uranium in ponds increases the risk of groundwater getting contaminated as these residues essentially leach through the upper unsaturated geological formation. In this context, a numerical model has been developed in order to forecast the U and its progenies concentration in an unsaturated soil. The developed numerical model is implemented in a hypothetical uranium tailing pond consisting of sandy soil and silty soil types. The numerical results show that the U and its progenies are migrating up to the depth of 90 m and 800 m after 10 y in silty and sandy soil respectively. Essentially, silt may reduce the risk of contamination in the groundwater for longer time span and at the deeper depths. In general, a coupled effect of sorption and hydrogeological parameters (soil type, moisture context and hydraulic conductivity) decides the resultant uranium transport in subsurface environment.
An Augmented Reality Device for Remote Supervision of Ultrasound Examinations in International Exercise Science Projects: Usability Study

Background Support for long-distance research and clinical collaborations is in high demand and has increased owing to COVID-19–related restrictions on travel and social contact. New digital approaches are required for remote scientific exchange. Objective This study aims to analyze the options of using an augmented reality device for remote supervision of exercise science examinations. Methods A mobile ultrasound examination of the diameter and intima-media thickness of the femoral and carotid arteries was remotely supervised using a head-mounted augmented reality device. All participants were provided with a link to a YouTube video of the technique in advance. In part 1, 8 international experts from the fields of engineering and sports science were remotely connected to the study setting. Internet connection speed was noted, and a structured interview was conducted. In part 2, 2 remote supervisors evaluated 8 physicians performing an examination on a healthy human subject. The results were recorded, and an evaluation was conducted using a 25-item questionnaire. Results In part 1, the remote experts were connected over a mean distance of 1587 km to the examination site. Overall transmission quality was good (mean upload speed: 28.7 Mbps, mean download speed: 97.3 Mbps, mean ping: 21.6 milliseconds). In the interview, participants indicated that the main potential benefits would be to the fields of education, movement analysis, and supervision. Challenges regarding internet connection stability and previous training with the devices used were reported. In part 2, physicians’ examinations showed good interrater correlation (interclass correlation coefficient: 0.84). Participants valued the experienced setting as highly positive. Conclusions The study showed the good feasibility of the chosen design and a highly positive attitude of all participants toward this digital approach. Head-mounted augmented reality devices are generally recommended for collaborative research projects with physical examination–based research questions.
THEORETICAL APPROACHES TO FORMATION OF THE MECHANISM OF QUALITY ASSURANCE OF HUMAN RESOURCES OF THE MACHINE-BUILDING ENTERPRISES

Theoretical approaches to improving the mechanism of quality assurance of human resources of the machine-building enterprises are formed. It is established that the basis of theoretical approaches to the mechanism of quality assurance of staff of the machine-building enterprises is the staff. A generalized definition of staff quality is provided. It is determined that the effectiveness of human resources quality management, the most complete implementation of the goals largely depend on the construction of a mechanism for staff quality assurance. It is proved that the goals of quality management should be taken into account in financial management from the standpoint of optimizing the cost of quality: staff performing processes and on which the work of the entire enterprise depends; resources purchased and used to manufacture products or perform services or works; management that affects the processes, projects and quality work of employees in the enterprise. The influence of the life cycle of staff quality assurance on the results of the enterprise, as well as on the state budget, internal and external labor market is studied. It is established that most of the analyzed methodological approaches to assessing the quality of human resources are based on the methodology of economic analysis of economic activity of the machine-building enterprises using such basic criteria as "effectiveness" and "efficiency". It is established that the comprehensive application of the basic principles of training and motivation in the organization is a defining prerequisite for staff development as a necessary component of quality assurance of enterprise management.
Problems of implementation of personalized medicine in medical cosmetology in Russia

At the present time, the 4P concept (predictive, preventive, personalised and participatory) is a prospective trend in development of clinical medicine. The concept is being actively introduced into diff erent medical specialities. However, the development of personalised approach in medical cosmetology as a speciality at the intersection of medical sciences (dermatology, maxillofacial surgery, plastic surgery, restorative medicine, general practice, psychiatry, clinical pharmacology, etc.) is at the stage of discussion. The concept of 4P medicine suggests, among other things, analysis of genetic risks and development of preventive procedures based thereon that would decrease the risk of cosmetological complications development. The review includes analysis of literature dated 2010-2020. The following databases in Russian and foreign languages were searched using the keywords and advanced search builders: E-Library, PubMed, Springer, Clinicalkeys, Google Scholar. In this paper, we introduce a novel compilation of the known gene polymorphisms that may be used for determination of the genetic risks in cosmetological patients.
Chemical Origin of Termination-Functionalized MXenes: Ti3C2T2 as a Case Study

MXenes represent a burgeoning family of two-dimensional (2D) functional materials with a variety of applications that highly rely on termination-mediated surface functionalization, but the understanding of termination is limited. Here, we take Ti3C2T2 (T = O, F, OH, and H) as an example of MXenes, to demonstrate how termination stabilizes the Ti3C2 monolayer matrix by saturating the nonbonding valence electrons of the surface Ti atom by the low-energy orbitals of the termination. This is achieved by orbitally resolved density of states analysis by simply yet efficiently manipulating the internal coordination of the octahedral crystal field to match exactly the Cartesian coordination. Highly degenerate 3d orbitals of surface Ti split in such a way that it exhibits pseudogaps whose widths predict a stability order Ti3C2O2 > Ti3C2F2 > Ti3C2(OH)2 > Ti3C2H2 > Ti3C2, consistent with Bader charge analysis, thermodynamic calculations, and experimental results. This new criterion could have implications in the gen.