Miracle-dz/UniFAR-FTUs huggingface dataset:
Management of Patients with Recurrent and Metachronous Oligometastatic Prostate Cancer in the Era of PSMA PET

Simple Summary Prostate-specific membrane antigen positron emission tomography (PSMA PET) is a modern imaging modality used in the management of patients with prostate cancer with improved accuracy in detecting lymph nodes and distant disease spread. In this paper, we discuss how the increasing use of PSMA PET is changing clinical management in patients with prostate cancer, specifically those previously treated for localized disease and now presenting with recurrence or low-volume metastatic disease spread. We also discuss how PSMA PET is affecting clinical trial design and interpretation. More clinical trials are needed to investigate whether the use of PSMA PET translates into improved patient survival or quality of life. Abstract Prostate-specific membrane antigen (PSMA) positron emission tomography (PET) scans have higher sensitivity and specificity for detecting lymph nodes or metastatic disease relative to conventional imaging in prostate cancer staging. Since its FDA approval and incorporation into treatment guidelines, the use of PSMA PET has increased in patients undergoing initial staging, those with recurrence after initial definitive treatment, and patients with metastatic disease. Although the early detection of metastatic lesions is changing disease management, it is unclear whether this impact on management translates into clinical benefit. This review will summarize evidence pertaining to the change in patient management due to PSMA PET use and will discuss the implications of PSMA PET on treatment decisions in prostate cancer, particularly in the settings of biochemical recurrence and metachronous oligometastatic disease.
The Functionality and Interactivity of Video Conferencing Technologies: A Synchronous Technology Adoption Model

In the past few years, educators started using synchronous video conferencing software like Google Meet, Microsoft Teams or Zoom, among others, in addition to traditional teaching methodologies. Therefore, this contribution examines the students’ perceptions about the functionality and interactivity features of these technologies, as well as the facilitating conditions of a higher education institution (HEI) in a Southern European context. A survey questionnaire integrated valid measures that were drawn from the relevant literature on technology adoption. The analysis was carried out through SmartPLS to shed light on the causal paths affecting the students’ intentions to continue using synchronous technologies in higher education. The results suggest that the students feel that the functionality of the conferencing software in terms of their ease-to-use and efficient designs, as well as their HEI's facilitating conditions, including the technical support they are given, and their accessibility to adequate resources, are affecting their intentions to continue using these interactive technologies, to achieve their learning outcomes.
THE MV - W (H-GAMMA) CALIBRATION FOR O6 TO A3 SUPERGIANTS.

The Mv-W(H-gamma) calibration of main-sequence stars of Millward and Walker (1985) is evaluated by observing bright supergiants in clusters. Fifty-two spectra of 39 O, B, and A supergiants combined with 19 higher dispersion spectra of 18 stars are studied. Wing profiles were generated by fitting a two-component, absorption-coefficient model to the H-gamma profiles. The calculated Mv data are compared to photometric values. It is observed that there is a difference in the present calibration and the Millward and Walker calibration due to the manner in which the wing profiles are defined; however, the nonlinear relation between the spectral types and W(H-gamma) found by Millward and Walker is confirmed.
An equivalent form of Lévy’s axiom schema

A generalized notion of ordinal inaccessibility is de- fined. A characterization of this notion in terms of normal ordinal functions yields as a consequence that a schema analogous to a form of Tarski's Axiom of Inaccessible Cardinals is equivalent to Levy's axiom schema unider the axiom of choice. This note supplies proof to the result announced in (I). Using ele- mentary ordinal theory alone we derive a schema that is equivalent to that of Levy in the presence of AC (the axiom of choice) and that has a simple relationship to Tarski's Axiom of Inaccessible Cardinals. R. Montague has obtained another equivalent form of Levy's schema as a consequence of a model-theoretic lemma proved in Montague (3). It turns out that our form and Montague's form of the Levy schema correspond to the two commonly stated forms of Tarski's Axiom of Inaccessible Cardinals. We mnake use of the notation and definitions of Levy (2), in particular we borrow the illegitimate con- venience of speaking of functions with domain the class of all ordinals. Actually, all our "functions" will be of this kind and instead of or- dinal-valued function defined for all ordinals we will write simply func- tion. A canonical example is the ordinal successor function. By weakly (strongly) inaccessible we shall mean im weiteren (im engeren) Sinne unerreichbar in the sense of (4), but inaccessible (unqualified) has the sense of (2 ). 1. Three schemata. Consider the following three statements:
TD 2719 - Os Impactos do aumento da licença-maternidade sobre os padrões de oferta de trabalho feminina ao nível das empresas

Este texto analisa os efeitos de mudanças voluntárias da licença-maternidade – por meio do Programa Empresa Cidadã (PEC) – de 120 dias para 180 dias sobre as contratações líquidas e os salários das trabalhadoras nas empresas que aderiram ao programa. Para tanto, foi empregado o método de pareamento com escore de propensão combinado ao de diferenças em diferenças. Os resultados revelaram que a extensão da licença-maternidade exerceu um impacto positivo e significativo nas contratações das trabalhadoras, e nulo para os salários de contratação. Como forma de testar a credibilidade da nossa estratégia empírica, foram estimados impactos nulos para anos anteriores ao início do programa, bem como para homens após o início do programa. Os resultados foram interpretados à luz de um arcabouço de competição imperfeita no mercado de trabalho, o qual sugere que os impactos estimados refletem um aumento na oferta de trabalho feminina para as empresas que aumentaram a duração da licença-maternidade.
Nueva evidencia en el tratamiento de la enfermedad renal diabética: ¿qué aporta la finerenona?

Contexto: la enfermedad renal diabética (ERD) es la primera causa a nivel mundial de enfermedad renal crónica (ERC) e impacta directamente en el riesgo cardiovascular y mortalidad de los pacientes con diabetes mellitus (DM). La finerenona, un antagonista selectivo del receptor mineralocorticoide (ARM), ha sido descrito en diversos estudios recientes como un fármaco que contribuye a la reducción de la progresión de la ERD y la disminución del riesgo cardiovascular, con un adecuado perfil de seguridad. Objetivo: realizar una revisión de la literatura sobre el impacto de la finerenona en la progresión del daño renal y el riesgo cardiovascular en los pacientes con ERD. Metodología: se realizó una búsqueda sistemática en diversas fuentes: PubMed (Medline, Biblioteca del Congreso de los Estados Unidos), Science Direct, Scopus, Embase y Lilacs; la búsqueda fue restringida a referencias en idioma español e inglés, sin límites en la fecha de publicación. Se utilizaron las siguientes palabras clave en el idioma inglés: diabetic renal disease, chronic kidney disease, diabetes mellitus, spironolactone, eplerenone, finerenone, mineralocorticoid receptor antagonist y sus correspondientes versiones en español. Resultados: Las referencias encontradas en la búsqueda fueron revisadas entre los diferentes autores para, posteriormente, proceder a realizar la elaboración del documento. Conclusiones: la finerenona es un medicamento que brinda cardio y nefroprotección en pacientes con ERD de fenotipo albuminúrico.
The ICD-11 Diagnoses in the Mental Health Field – An Innovative Mixture

The development of ICD-11 in the mental health field has been innovative in several ways. Perhaps most notable is that it has become equally relevant to clinicians and re­ searchers. Before discussing these two aspects in more detail, it should be mentioned that the processes by which the ICD-11 was created were also innovative and, moreover, that clinical psychologists and psychiatrists were equally involved at several crucial points in the ICD-11 development. This began with Dr. Geoffrey Reed, a US clinical and medical psychologist, as the responsible WHO senior project officer for new developments in the mental health field and who set important impulses at all stages of the process (e.g., Reed, 2010). From the beginning, the Lebanese psychologist Brigitte Khoury and the Mexican psy­ chologist Maria Elena Medina-Mora served on the International Advisory Group for this field. Both have published on important milestones and outcomes of regional meetings (Khoury et al., 2011; Medina-Mora et al., 2019). Furthermore, the author of this editorial, in his capacity as a psychologist, was one of the working group leaders of the ICD-11 development (Maercker et al., 2013). This new way of composing decision-making bodies represented an important step in the development of the international Mental and Be­ havioral Disorder classification. This was further supported by the inclusion of clinicians and researchers from the fields of clinical social work and psychiatric nursing sciences in the committees. Thus, the whole ICD-11 development relied on a very multidisciplinary process.
Empirical Investigation on the Design and Fabrication of Cassava Grating Machine of 4.5kw

Abstract: Cassava products has been diversified ranging from one product to another, such as the use of cassava in livestock feed, means that more maize and other feed materials used in the past can now be available for other uses. Diverse uses of cassava flour food products such as its glucose for pharmaceuticals products as well as food supplements, and to make alcohol and other beverages, would enhance farmers to cultivate more because of its financial benefits. There is a gap between industrial processors and producers of cassava products that must be strengthened. The Federal government of Nigeria’s mandate to include 10% HQCF (High Quality Cassava Flour) flour in all products of wheat flour for bread-making has led to farmers and food processors demanding equipment and machinery to increase production. The aim of this research is to design and fabricate a cassava grating machine of 4.5kw and to carry out performance evaluation of the machine which met the objective of effective grating replacing the wooden grating machines. The materials were sourced locally which led to cost effectiveness of the machine. After, the machine was designed and fabricated, the performance evaluation of the machine was tested, the feed rate and grating rate were obtained as a function of time. The average feed rate of the machine was found to be 30kg/min which gave an input capacity of 1800kg/hr. Authors reported that it takes 1 hour to completely grate 740kg of cassava tubers. Keywords: Power Transmission: Tacking: Stitching: Rotational Torgue: Speed Transmission: Design Calculations, Tabe Shear, Bending Machine: Welding machine
Existence and uniqueness of solution for a class of nonlinear sequential differential equations of fractional order

Two-term semi-linear and two-term nonlinear fractional differential equations (FDEs) with sequential Caputo derivatives are considered. A unique continuous solution is derived using the equivalent norms/metrics method and the Banach theorem on a fixed point. Both, the unique general solution connected to the stationary function of the highest order derivative and the unique particular solution generated by the initial value problem, are explicitly constructed and proven to exist in an arbitrary interval, provided the nonlinear terms fulfil the corresponding Lipschitz condition. The existence-uniqueness results are given for an arbitrary order of the FDE and an arbitrary partition of orders between the components of sequential derivatives.
Drag and lift forces on microscopic bubbles entrained by a vortex

The forces that act on bubbles as they are entrained by a vortex are measured using particle image velocimetry. Triple exposure images are used to measure the velocity and acceleration of the fluid and the bubbles simultaneously. Distinction between phases is achieved by using fluorescent particles as liquid flow tracers. The buoyancy, pressure, and inertia forces are computed from the data, while the drag and the lift forces are determined from a force balance on each bubble. It is found that in the present range of bubble diameters, 500 μm<d<800 μm, and Reynolds numbers, 20<Re<80, the drag on a bubble is similar to that on a solid body. Vorticity does not have a significant effect on the drag coefficient. The lift coefficients are significantly higher than currently available analytical and numerical estimates. The coefficients are independent of the Reynolds number and are proportional to the fourth root of the local vorticity. Estimates of the Bassett force show that it can be neglected in the present.
Compact H II regions in the far-infrared

Far-infrared (40-150 microns) observations of W51 (G49.5-0.4), K3-50, DR 21, NGC 7538, and W3(OH) are presented and discussed. At these wavelengths each source is dominated by a small bright component closely associated with a compact H II region. Their spectra can be explained as emission by dust at temperatures of 30-50 K. Some of the objects appear to be optically thick out to wavelengths of about 60 microns. Of the 10 source components in the five regions, at least four may be powered by pre-main-sequence stars. The far-infrared data are consistent with depletion of volatile components of the dust within compact H II regions, but do not clearly require destruction or expulsion of refractory grains. The bulk of the dust which emits primarily in the far-infrared must lie in a dense shell immediately outside the ionized zone. The sources are possible precursers to open clusters with stellar masses in the range from 1,000 to 10,000 solar masses.
‘Torus’ distribution of interstellar helium pickup ions: Direct observation

A‘torus’‐like velocity distribution of the helium pickup ions has been detected in interplanetary space by GEOTAIL. A statistical survey shows that the observation probability of the ‘torus’ distribution amounts to nearly 20% and that the distribution pattern depends on the local magnetic field directions and turbulence levels. These results support the recent finding of a low pitch angle scattering rate and a large mean free path.
Liquid jet generated by thermocavitation bubbles within a droplet

High-speed video imaging was used to study the dynamic behavior of cavitation bubbles induced by a continuous wave (CW) laser into highly absorbing droplets water containing copper nitrate (CuNO4). The droplet lays horizontally on a glass surface and the laser beam (λ=975 nm) propagates vertically from underneath, across the glass and into the droplet. This beam is focused ζ=400 μm above the glass-liquid interface in order to produce the largest bubble as possible (Rmax ~ 1mm). In our experiment the thermocavitation bubbles are always in contact with the substrate, taking a hemispherical shape, regardless of where the laser focal point is, as opposed to the other methods that involved nano and picosecond laser pulses, where bubbles may nucleate and grow within the bulk of the fluid. We focus on the liquid jet which emerges out the droplet at velocities of about 3 m/s, due to the acoustic pressure wave (APW) emitted immediately after the bubble collapse, and after it breaks up into a secondary droplet or droplets depending of the droplet’s volume, showing an alternative way of droplet generator that is simplest, light and cheaper. The dynamics of cavitation bubbles in confined geometries (drops) offers a rich hydrodynamic and the liquid jet generated after the bubble collapse could be used like acoustic waveguide, as was showed by Nicolas Bertin et. al.
La ecuación de Navier-Stokes y multifractales

There is currently no general theorem on the existence and unicity of solutions to the Navier-Stokes equation, which describes the flow of a viscous and incompressible fluid. This is an open problem at the international level, known as the millennium prize problem, for which the Clay Institute of France is offering one million dollars since may 2000. The purpose of this article is to present a brief revision of the most important aspects of the evolution and current status of the problem. Our contribution is the analytical description of turbulence, fully developed, through the resolution rates and the features of multifractal processes, as a collection of generalized Cantor processes. We present four models for the distribution of velocity variations. The first one is based on the life times and risk functions for the interaction between the vortices and their later fragmentation in ever smaller and more numerous vortices. The second one is based on potentiated Bernoulli tests, and we found the number of features, the spectrum, and the structure function. We found the relationship of the shape parameters with the box dimension of the maximum spectrum as well as with the local dimensions and we described qualitatively the associated tree. The above-mentioned rates serve as support, not only for the description of a three-dimensional model of intermittent turbulence that generalizes the Kolmogorov paradigmatic result, but also for the energy transferred in each stage of the fractalization process, and also for the number of characteristic exponents, which produces a higher level for Hausdorff’s dimension of the set of singularities of the solution. Keywords: Navier-Stokes, turbulence, intermittency, multifractals, velocity gradients.
A spectrographic survey of 21 planetary nebulae.

A blue spectral survey and coarse photographic photometry are presented for 21 planetary nebulae, of which eight have not been heretofore observed with any detail. Eight of the nebulae have been observed photoelectrically. Most of the planetaries studied are of intermediate excitation; five present no detectable He ii lines, and two are of high excitation with powerful He ii lambda4686. The chief value of the photographic part of the study is to locate objects deserving of further study. Rough electron densities are derived for the nebulae from either or both of the O ii or Ar iv doublet ratios, and electron temperatures from the O iii lines. Values are generally within the normal range except for Hb 12, for which N/sub e/ may be as high as 4 x 10$sup 5$. (AIP)
Integrating religiosity into a technology acceptance model for the adoption of mobile payment technology

This research studies the effects of the religiosity on financial technology (fintech) adoption. The study examines religiosity as part of the Technology Acceptance Model (TAM) dimensions for the adoption of mobile payment technology. We explore the role of religiosity in TAM and recommend several policies for related organizations. The study uses professional sample calculation from 113 traditional markets under Perumda Pasar Jaya as a business entity whose capital is wholly or mostly owned by the regional government through regional assets of DKI Jakarta Province, Indonesia, which use mobile payment technology. We obtained 363 respondents from June 2020 to June 2021, coinciding with the Covid-19 pandemic. Hypothesis testing was done employing SmartPLS 3.2. 9 software and questionnaires. The study also adapts previous studies to ensure the questionnaires are relevant to the research objects. The research result show that religiosity explained the formation of TAM by small businesses in traditional markets under Perumda Pasar Jaya Management. Religiosity and the adoption of mobile payment technology determined whether a user used fintech or not. As the research period was limited to June 2020 - June 2021, including field research in the traditional markets, newer TAM mobile payment technology development and other TAM mobile payment-based research were not included. This research offers a new TAM development model using religiosity for mobile payment adoption in traditional markets.
The heat transport and spectrum of thermal turbulence

In this paper a theoretical investigation is made of various properties of the steady-state inhomogeneous turbulent convection of heat in a fluid between horizontal conducting surfaces. An upper limit to the heat transport is found subject to the constraint that some minimum eddy size exists which is effective in this transport. The spectrum of convecting motions, the mean thermal gradients at each point and the eddy conductivity are then determined in terms of the minimum eddy size. The relation between the boundary conditions and eddy size is studied by an extension of the work of Pellew & Southwell using the mean thermal gradients deduced when n0 modes of motion are present to establish the Rayleigh number at which the (n0+1)th mode first becomes unstable. In a final section the spectra and mean-square values of the fluctuating velocity and temperature fields are estimated from the Boussinesq form of the hydrodynamic equations. The previously reported experimental heat transports are within 10% of those predicted. The discrete transitions are within the error limits of the observations. However, further data must be mgathered to justify the use of minimum eddy size as a defining parameter in situations of geophysical scale.
Sources of variability in auditory brainstem response thresholds in a mouse model of noise-induced hearing loss

Numerous and non-acoustic experimental factors can potentially influence experimental outcomes in animal models when measuring the effects of noise exposures. Subject-related factors, including species, strain, age, sex, body weight, and post-exposure measurement timepoints, influence the observed hearing deficits. Experimenter effects, such as experience with experimental techniques and animal handling, may also factor into reported thresholds. In this study, the influence of subject sex, body mass, age at noise exposure, and timepoint of post-exposure recording are reported from a large sample of CBA/CaJ mice. Auditory brainstem response (ABR) thresholds differed between noise-exposed and unexposed mice, although the differences varied across tone frequencies. Thresholds across age at noise exposures and measurement delays after exposure also differed for some timepoints. Higher body mass correlated with higher ABR thresholds for unexposed male and female mice, but not for noise-exposed mice. Together, these factors may contribute to differences in phenotypic outcomes observed across studies or even within a single laboratory.
The Influence of Obesity and Self-Confidence on Students' Physical Self-Concept; Correlation Study

This study aims to analyze: (1) The effect of obesity on physical self-concept. (2) The effect of self-confidence on physical self-concept. (3) The effect of obesity and self-confidence on physical self-concept. This type of research is quantitative with an ex post facto approach. The population in this study were junior high school students in Kulon Progo Regency. The sampling technique used was purposive sampling to collect 60 obese children from schools in Kulon Progo Regency. Inclusion criteria for cases and controls were obese children in the age range of 11-15 years. The instrument used is a questionnaire—data analysis technique using ANOVA analysis. The results showed that (1) there was a significant relationship between obesity and physical self-concept, with a significance value of 0.000 <0.05. (2) there is a significant relationship between self-confidence and physical self-concept, with a significance value of 0.002 <0.05. (3) there is a significant effect between obesity and self-confidence on physical self-concept, with a sig. 0.000 < 0.05.