Miracle-dz/UniFAR-FTUs huggingface dataset:
A Textual Analysis of President Akufo-Addo’s 12th Covid–19 Address

The study examined the social and political circumstances in Ghana which evolved because of the pandemic created by COVID-19, and the extent to which President Akufo-Addo was able to effectively use the medium of speech to manage this global health emergency. This study focused on the stylistic choices of the speech and investigated how different sentence structures, repetitions, political jargon, and other linguistic characteristics were deployed. Textual analysis involves the appreciation of a text while explaining its ideological and cultural dimensions (Fursich, 2009). This study was underpinned by the Narrative Paradigm Theory and Sociolinguistics. Under Narrative Paradigm Theory, narratives have a plot and characters that are involved in an interaction and can therefore be seen as a narrative in form and function. Sociolinguistics shows how language can be presented in specific contexts of social life, and how it reflects and then includes meaning and structure in those contexts (Schiffrin, 1997). Also, textual analysis as a qualitative research methodology was used for this study, and as an interpretive approach, it concentrated on the embedded cultural and ideological positions on the material. The findings from this study showed that the speech that was in a narrative mood incorporated all the achievements and challenges identified during the pandemic. It also provided cases of semantic analysis of words and meaning, relations among words that included metaphors, semantics, argumentative, narrative, and cognitive frames.
Improving Problem-Solving and Communication Skills in Automotive Vocational Education through the Development of Teaching Factory Model with Problem-Based Learning (TEFA-PBL) Concept

Preliminary research showed that the learning process could have been more optimal, and this led to the research to develop a TEFA Model with the PBL concept as a valid, practical, and effective method of improving the problem-solving and communication skills of Automotive Vocational Education students. The process involved using the Research and development approach through the application of 4D development procedures of Defining, Designing, Developing, and Disseminating. The study resulted in the TEFA-PBL model with seven learning syntaxes. The syntaxes were (1) troubleshooting the problem, (2) organizing the order, (3) collaborative problem solving, (4) executing an order, (5) quality control, (6) presentation and discussion, and (7) assessment. Furthermore, scenarios were generated to guide the learning activities of lecturers and students directed towards achieving fundamental and global 21st-century automotive vocational skills such as good problem-solving, communication, and collaboration skills. The syntax and scenarios of the learning model produced were feasible, valid, and practically applicable to produce graduates with ready-to-use and competitive skills. It, therefore, signifies that the TEFA-PBL model developed is an innovative solution to improve the quality of automotive vocational learning at different levels, especially universities, to produce graduates with ready-to-use and competitive skills.
Effect of Extraction Method and Solvent Type on Total Phenolics Content, Total Flavonoid and Antioxidant Activity of Pegagan Extract (Centella asiatica (Linn.) Urban)

Background: Centella asiatica (CA) or pegagan or horse foot leaves is one of the traditional plants widely used to treat various diseases. This study aims to evaluated the content of total phenolics and total flavonoids, as well as the antioxidant activity of Centella asiatica extracts from different methods and solvents. Methods: The sample was divided into three groups, (70% ethanol maceration, methanol maceration and water infundation). Total phenolic compounds in the extract were determined by the Follin-Ciocalteu method, total flavonoid content was determined by the aluminum chloride colorimetric assay method, and antioxidant activity was assessed by the immersion DPPH free radicals method. Determination data of IC50 was assessed by regression test and differences between the three extract groups were tested by ANOVA or Kruskal Wallis test. Results: The highest total phenolics and total flavonoid were obtained in Centella asiatica extract with water solvent, 251.88 ± 0.96 mg/g GAE and 7.26 ± 0.03 mg/g QE, followed by 70% ethanol and methanol. In addition, the best antioxidant activity was also shown in the extract with water, namely 24.09 ± 0.01. The difference test results between all groups showed significant results (p<0.05) in all parameters. Conclusion: The best content of total phenolic, total flavonoid, and antioxidant activity was obtained by infundation with water solvent. In the maceration method, the best content of the three parameters measured was obtained in the group with ethanol solvent.
Object Spatial Impedance Achieved by a Multifinger Grasp With Hard-Point Contact

This article identifies the space of spatial impedance behaviors that can be achieved by a grasp of a multifinger hand in which each fingertip makes hard-point contact with the held object. The dimension of the space of realizable impedances for a given number of fingers is determined analytically. A set of necessary and sufficient conditions on impedance matrices that can be realized by a given grasp is developed and the physical significance of these conditions is identified. The space of impedances that can be achieved by a hard point grasp is a hyperplane in the space of all possible impedance behaviors. A process to achieve an arbitrary full-rank impedance in the hyperplane with a grasp having the minimum number of fingers is developed. With this process, any spatial impedance behavior in the hyperplane can be attained with a three-finger grasp by properly selecting: first, the locations where fingertips contact the held object, and second, the translational impedance provided by a finger at each of these locations.
Time-dependent inverse box-model for the estuarine circulation and primary productivity in the Strait of Georgia

During 2002–2006, a comprehensive set of observations covering physical, biological, radiative and atmospheric parameters was obtained from the southern Strait of Georgia (SoG), Western Canada by the STRATOGEM program. Monthly time series of estuarine layer transports over 2002–2005 were estimated using a time-dependent 2-box model in a formal inverse approach. These transports are then consistent with the temperature and salinity fields, as well as riverine freshwater inflow (R) and atmospheric heat fluxes. Uncertainty was analyzed by resampling observations using bootstrap methods. The transport time series were then combined with observations of nutrient concentrations to construct monthly time series of nutrient uptake for nitrate, phosphate, and silicic acid. Analysis of these time series suggests that the SoG estuarine circulation is not very sensitive to the seasonal changes of R. Comparison of the surface layer transport (U1) and R yields the first observational relationship between the SoG estuarine circulation and R. This relationship (U1=2.68 m s × 10 R) is consistent with estuarine theories. Although the flows change slightly with the freshet, a 5-fold change in R results only in a 40% change in U1. Based on the calculated sink of near-surface nutrients, net primary productivity is estimated to be 212 gC m yr, which is similar to values obtained differently in similar estuaries. Comparison of the nitrate and phosphate uptake rates suggests that the primary productivity (PP) is mainly new PP during spring and summer.
Effectiveness of Medication Reconciliation in a Chinese Hospital: A Pilot Randomized Controlled Trial

Background Implementing medication reconciliation (MR) was complex and challenging because of the variability in the guidance provided for conducting. The processes of MR adopted in China were different from that recommended by the World Health Organization. A pilot study to inform the design of a future randomized controlled trial to determine the effectiveness of these two workflows was undertaken. Methods Patients taking at least one home/regular medication for hypertension, diabetes, or coronary heart disease were recruited at admission, and then were randomized using a computer-generated random number in a closed envelope. In the study group, the pharmacist reviewed electronic medical record systems before communication with patients. In the control group, pharmacists communicated with patients at patient’s admission. The time investment of pharmacists for MR process, the number of unintended medication discrepancies, and physician acceptance were tested as outcome measures. Results One hundred and forty adult patients were randomized, of which 66 patients in the intervention received MR within 24 hours, while 58 patients in control received MR at some point during admission. The most common condition in the study group was hypertension (coronary heart disease in the control group). The workflow of the study group can save an average 7 minutes per patient compared with the WHO recommended process [17.5 minutes (IQR 14.00, 28.25) vs 24.5 minutes (IQR17.75, 35.25), p = 0.004]. The number of unintended discrepancies was 42 in the study group and 34 in the control group (p = 0.33). Physicians’ acceptance in the study and control groups were 87.5% and 92.3%, respectively (p = 0.87). Conclusion The results suggest that changes in outcome measures were in the appropriate direction and that the time limit for implementing MR can be set within 48 hours. A future multi-centre RCT study to determine the effectiveness of MR is feasible and warranted.
Sustained high HIV incidence among men who have sex with men in Jiangsu province, China: based on the limiting-antigen avidity EIA method and six consecutive surveys, 2016–2021

Background The epidemic of HIV infection among men who have sex with men (MSM) is a major public health concern in some parts of China, but data on trends in HIV incidence are limited. This study aimed to examine the trends in HIV incidence and factors associated with recent HIV infection among MSM in Jiangsu province, China, based on the limiting-antigen avidity enzyme immunoassay (LAg-Avidity-EIA) method. Methods Six consecutive surveys were implemented among MSM throughout Jiangsu province from 2016 to 2021. Participants were recruited in three ways. Socio-demographic and behavioral information were collected through face-to-face interviews. Venous blood samples were taken to test for HIV and syphilis. HIV incidence was estimated using the LAg-Avidity-EIA method. Chi-square trend tests were used to observe trends over the years. Multivariate regression analyses were used to identify factors associated with recent HIV infection. Results A total of 15,401 participants were enrolled in the study. The prevalence of HIV infection ranged from 8.0 to 9.8%, with no consistent rise or fall over the years (P = 0.189). HIV incidence ranged from 5.0 to 9.0%, and no uptrend or downtrend was shown (P = 0.418). MSM who lived locally for more than 2 years (aOR = 1.366, P = 0.019), had a lack of comprehensive HIV knowledge (aOR = 1.643, P = 0.031), had engaged in unprotected anal intercourse (UAI) in the past 6 months (aOR = 7.373, P < 0.001), had been tested for HIV within 12 months (aOR = 1.292, P = 0.035), and tested positive for syphilis (aOR = 2.840, P < 0.001) were likely to be recently infected with HIV. Conclusions HIV incidence among MSM has remained at a high level in Jiangsu province. In China, health education, condom use, and HIV/syphilis testing should continue to be top priorities for HIV prevention among MSM to reduce HIV transmission.
Coexistence of Vertebral and Intervertebral Disc Changes in Low Back Pain Patients—In Depth Characterization with Same Day MRI and CT Discography

The aim of this study was to investigate to what extent annular fissures, vertebral and endplate changes, and Modic changes (MCs), coexist in low back pain (LBP) patients by using multiple imaging modalities. Sixty-two LBP patients (mean age 45 years, range 24–63, 53% men) were examined with same-day CT-discography and MRI. Intervertebral discs punctured for discography (n = 204) were evaluated on MRI [Pfirrmann grade, High-Intensity Zone (HIZ)] and on CT-discograms [Modified Dallas Discogram Score (DDS)]. DDS≥ 1, i.e., disc fissures involving the outer annulus were further digitomized into delimitable fissuring (<50% of annulus affected) or non-delimitable annular fissuring. Using both MRI and CT, adjacent vertebrae and endplates were assessed for MC, vertebral sclerosis, and a modified endplate defect score (EPS). In 194 discs the contrast agent was adequately injected during discography, of which 160 (83%) displayed outer annular fissures, with 91 (47%) of the latter being delimitable fissures. Most discs with delimitable fissures were moderately degenerated; 68% Pfirrmann grade ≤3, 71% EPS ≤ 2, and 12% displayed MC. The majority (76%) of MCs were associated with advanced adjacent disc degeneration; 84% Pfirrmann grade ≥4, 76% with non-delimitable annular fissuring, 59% EPS≥ 4, and 34% EPS of 3. A total 95 HIZ (47%) were found, of which 54 had delimitable fissuring, while the remainder displayed non-delimitable fissuring. Vertebral sclerosis was commonly observed (26%), both with MCs (73%) and without MCs (27%), and not specifically linked to MC type 3. A total of 97% of segments with vertebral sclerosis displayed outer annular fissures. These findings were significant (0.046 > p > 0.0001), except between HIZ and adjacent sclerosis (p = 0.303). To conclude, the present study confirmed a close interplay between the disc and adjacent vertebra and endplates. The fact that a majority of discs with delimitable annular fissures did not coexist with pronounced endplate changes and/or MCs, however, supports the theory that disc fissuring is an early event in the degenerative cascade. This was further supported by the fact that MCs were strongly linked to extensive disc fissuring and to advanced endplate damage. Further, vertebral sclerosis was common also in vertebra without MCs and strongly associated to annular fissuring, indicating that sclerosis is a previously underestimated feature of a general degenerative process.
Evaluation of N-Acetylmannosamine Administration to Restore Sialylation in GNE-Deficient Human Embryonal Kidney Cells.

BACKGROUND A key mechanism in the neuromuscular disease GNE myopathy (GNEM) is believed to be that point mutations in the GNE gene impair sialic acid synthesis - maybe due to UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (GNE) activity restrictions - and resulting in muscle tissue loss. N-acetylmannosamine (ManNAc) is the first product of the bifunctional GNE enzyme and can therefore be regarded as a precursor of sialic acids. This study investigates whether this is also a suitable substance for restoring the sialic acid content in GNE-deficient cells. METHODS A HEK-293 GNE-knockout cell line was generated using CRISPR-Cas9 and analyzed for its ability to synthesize sialic acids. The cells were then supplemented with ManNAc to compensate for possible GNE inactivity and thereby restore sialic acid synthesis. Sialic acid levels were monitored by immunoblot and high performance liquid chromatography (HPLC). RESULTS The HEK-293 GNE-knockout cells showed almost no polysialylation signal (immunoblot) and a reduced overall (-71%) N-acetylneuraminic acid (Neu5Ac) level (HPLC) relative to total protein and normalized to wild type level. Supplementation of GNE-deficient HEK-293 cells with 2 mM ManNAc can restore polysialylation and free intracellular sialic acid levels to wild type levels. The addition of 1 mM ManNAc is sufficient to restore the membrane-bound sialic acid level. CONCLUSIONS Although the mechanism behind this needs further investigation and although it remains unclear why adding ManNAc to GNE-deficient cells is sufficient to elevate polysialylation back to wild type levels - since this substance is also converted by the GNE, all of this might yet prove helpful in the development of an appropriate therapy for GNEM.
Chemical Composition of Essential Oils and Supercritical Carbon Dioxide Extracts from Amomum kravanh, Citrus hystrix and Piper nigrum ‘Kampot’

The fruits of Amomum kravanh, Citrus hystrix and Piper nigrum ‘Kampot’ are traditionally used as spices in Cambodian cuisine. In this study, the chemical composition of essential oils (EOs) and supercritical CO2 extracts from all three species was determined using GC-MS, with two columns of different polarity (HP-5/DB-HeavyWAX). Differences between the chemical profile of the EOs and CO2 extracts were observed for all species. The greatest difference was detected in A. kravanh EO containing mainly eucalyptol (78.8/72.6%), while the CO2 extract was rich in fatty acids (13/55.92%) and long-chain alkanes (25.55/9.54%). Furthermore, the results for the CO2 extract of this species differed, where tricosane (14.74%) and oleic acid (29.26%) were the main compounds identified when utilizing the HP-5 or DB-HeavyWAX columns, respectively. Moreover, the EO and CO2 extract from P. nigrum ‘Kampot’ fruits and the CO2 extract from C. hystrix fruit peel, containing respective amounts 34.84/39.55% (for EO) and 54.21/55.86% (for CO2 extract) of β-caryophyllene and 30.2/28.9% of β-pinene, were isolated and analyzed for the first time. Generally, these findings suggest that supercritical CO2 could potentially be used for the extraction of all three spices. Nevertheless, further research determining the most efficient extraction parameters is required before its commercial application.
Assessment of macrofungal diversity in a Silver Fir plantation in Sardinia (Italy) using a standardized sampling procedure

The knowledge of macrofungal diversity associated with Silver Fir forests in Italy is quite scarce. Only a little information is available about macrofungal communities from some Ligurian and Tuscan Silver Fir sites. This study aims to assess the macrofungal diversity of a Silver Fir plantation in Sardinia by the application of a standardized sampling procedure. A total of 606 sporomata were collected and 52 Basidiomycota were identified. The high value of the Shannon Index indicated a considerable level of macrofungal diversity in this plantation. The results were also compared with the diversity indices obtained by a previous 3-years long sampling methodology in the same site. The comparison of the macrofungal diversity values of the Sardinian site with those of the Ligurian Silver Fir forest revealed interesting similarities among natural versus planted coniferous forests.
Repositioning Entrepreneurial Education Planning And Skill Acquisition For Economic Recovery Sustainability In Post Covid-19 Era

The management of entrepreneurship involves responsibility for broad decision on policies and the ability to ensure that these decisions are executed effectively for societal benefit. Therefore repositioning entrepreneurial education and skill acquisition for economic recovery sustainability in post CONVI-19 era becomes imperative. The paper gives light on the understudied. Thereafter the paper defines key terms such as entrepreneurial, education, and expounds on the strategies for repositioning effective entrepreneurial education in post COVID-19 era. The concept of entrepreneurial skills acquisition, and relevance entrepreneurial education planning skills acquisition in post COVID-19 era have been examined. The paper further elaborated on sustainable economic recovery, incessant education process as mechanism for economic recovery sustainability, elements that enhance economic growth and roles of the entrepreneurs to the development of Nigeria. This paper concluded that effective repositioning of entrepreneurial education will enhance skill acquisition which will serve as a link to youth empowerment skills sustainability and economic growth. It was recommended among others that government should make entrepreneurship education a compulsory subject/course at all levels of education for sustainable development at the present and posterity.
Hybrid Pulse-Width Modulation Strategy With Reduced High-Frequency Common-Mode Voltage to Lower RMS Motor Leakage Current for a Three-Level Neutral Point Clamped Converter

Due to the capacitive nature of Common-mode impedance, high-frequency Common-mode voltage due to high switching frequency leads to an increase in RMS leakage current, which, in turn, causes higher power loss, Electromagnetic Interferences, and deteriorated harmonic distortion in the three-level Neutral-Point-Clamped converter. Recently-proposed pulse-width modulation type 1 with reduced Common-mode-voltage magnitudes, zero average Common-mode-voltage, and improved harmonic distortion has been presented for the three-level Neutral-Point-Clamped converter. However, the high-frequency Common-mode voltage could be further mitigated by reducing the number of CMV variations. Therefore, this article presents a hybrid pulse-width modulation scheme featuring reduced Common-mode-voltage magnitudes and variations, zero average Common-mode-voltage, and improved harmonic distortion. The Common-mode-voltage variation reduction is realized by re-arranging the order of the switching states in the recently-proposed scheme in a carrier period. The resulting modified sequences type 1 suffer simultaneous switchings between two phase-legs, hence leading to Common-mode-voltage spike due to deadtime. Hence, another type of modified sequences (type 2) is utilized with the modified sequences type 1 and the information of three-phase currents, hence the term “hybrid”. Results under Volt-per-Hertz-2.2KW-rated induction motor with different loading conditions in the Three-Level Neutral-Point-Clamped Converters indicate that at rated frequency of 50Hz, the proposed scheme leads to a noticeable decrease in RMS leakage current while producing similar-to-better harmonic distortion at the expense of slight reduction of the efficiency of a converter as opposed to the recently-proposed Reduced-Common-mode-voltage Pulse-width modulation type 1 with improved switching loss and Phase-Opposition-Disposition-Sinusoidal Pulse-width modulation.
A Security Situation Prediction Model for Industrial Control Network Based on EP-CMA-ES

To solve the problem of industrial control network (ICN) security situation prediction, this paper proposes a security situation prediction model for ICN based on evidential reasoning (ER) and belief rule base (BRB). First, this paper analyzes multiple factors influencing the security situation of the ICN, establishes a framework for security situation assessment, employs the ER algorithm for attribute fusion, and derives the security situation value of the ICN. Second, using historical data combined with expert knowledge, a security situation prediction model for ICN based on the BRB is constructed. Additionally, an extended projection covariance matrix adaptive evolution strategy (EP-CMA-ES) optimization algorithm is proposed, which is employed to optimize the parameters of the prediction model. The model not only comprehensively uses qualitative knowledge and quantitative data, but also integrates more uncertain information, and the reasoning process is interpretable. It also solves the subjectivity problem of expert knowledge, overcomes the problem of small amount of data caused by the difficulty of collecting industrial control safety data, and improves the accuracy of model prediction. Finally, prediction experiments were conducted on industrial datasets, confirming the feasibility and effectiveness of the security situation prediction model for ICN and the EP-CMA-ES optimization algorithm proposed in this paper.