Miracle-dz/UniFAR-FTUs huggingface dataset:
Effectiveness of Agile Design in Wrap-Around Content Development

ODL is growing at The University of the West Indies and on the premise of increasing access, the demands on the curriculum development unit of the institution’s fourth campus – The Open Campus, has increased by more than 300 percent. This paper addresses issues of effectiveness in an agile learning design process which relies on the wrap around content development method. The method assumes efficiencies in the production of a greater volume of course materials that utilize fewer resources. The paper discusses the practical implementation of the agile learning design in seven (7) undergraduate and four (4) graduate programmes over a twelve (12) month development cycle – February 2015 to January 2016, paying attention to the use of templates to focus the content development process; use of OER to reinvent the learner experiences with the course materials; redesigned orientation and training of course developers; and streamlining and standardization of policies, protocols and processes. With the institutional commitment to increasing access and the high expectations placed on the curriculum development unit for accelerated course development, the paper discusses agile learning design and the successes and challenges experienced in using the wrap around method for achieving scale and sustainability in course design and development. In this setting how can the institution assure sustainability and effectiveness in the production of its online course materials? Does use of an agile learning design lead to development of course materials at the required quality standard? Are the processes sustainable? What are the efficiencies for the institution? The paper also addresses the management of change, responsiveness to change in the agile learning design and will provide an indicative assessment of the effectiveness of the institutional processes. The outcomes are intended to be part of a continuing assessment over the life of a two (2) year course development project.
Edinburgh Research Explorer Aquirickettsiella gammari’ (Gammaproteobacteria

Invasive and non-native species can pose risks to vulnerable ecosystems by co-introducing bacterial pathogens. Alternatively, co-introduced bacterial pathogens may regulate invasive population size and invasive traits. We describe a novel candidate genus and species of bacteria ( ‘ Candidatus Aquirickettsiella gammari ’ ) found to infect Gammarus fossarum , from its native range in Poland. The bacterium develops intracellularly within the haemocytes and cells of the musculature, hepatopancreas, connective tissues, nervous system and gonad of the host. The developmental cycle of ‘ Candidatus Aquirickettsiella gammari ’ includes an elementary body (496.73 nm ± 37.56nm in length, and 176.89nm ± 36.29nm in width), an elliptical, condensed spherical stage (737.61nm ± 44.51nm in length and 300.07nm ± 44.02nm in width), a divisional stage, and a spherical initial body (1397.59 nm ± 21.26nm in diameter). We provide a partial genome for ‘ Candidatus Aquirickettsiella gammari ’ , which clades phylogenetically alongside environmental 16S rRNA sequences from aquatic habitats, and bacterial symbionts from aquatic isopods ( Asellus aquaticus ), grouping separately from the Rickettsiella , a genus that includes bacterial pathogens of terrestrial insects and isopods. Increased understanding of the diversity of symbionts carried by G. fossarum identi ﬁ es those that might regulate host population size, or those that could pose a risk to native species in the invasive range. Identi ﬁ cation of ‘ Candidatus Aquirickettsiella gammari ’ and its potential for adaptation as a biological control agent is ex- plored. tissues. The infects the cytoplasm of hepatopancreatic epithelia (where musculature, gill, gonad, nerve and haemocytes, manifesting in late stages as systemic infection. visible pathologies include a white iridescent appearance to infected amphipods, particularly their muscle tissues. The bacterium passes through a four-step development cycle including: the elementary body (smallest developmental stage); an elliptical, condensed sphere stage; division; and a spherical initial body (but not necessarily in that order). All developmental stages take place within a vacuole separating the bacteria from the host cell cytoplasm; however, the elementary body (infective stage) is predicted to be able to survive outside the host cell. Genome sequence data of novel species must show close relatedness through the phylogenetic methods used by this study, and gene conservation relative to the type species.
Edinburgh Research Explorer "Passing through difficult times"

Purpose This study was conducted to explore the perceptions of perinatal women and key maternal care health workers about perinatal depression and the health service needs required to inform development of a culturally sensitive and acceptable psychosocial intervention. This qualitative study used a descriptive exploratory design; it is the first phase of a larger mixed methods study aimed at adapting a psychosocial intervention for perinatal depression. We conducted in-depth interviews with 22 women who screened positive for depression using a locally validated Chichewa version of the Edinburgh Postnatal Depression Scale at antenatal and postnatal clinics in 1 rural and 1 urban health care setting in Lilongwe District, Malawi. We also conducted 10 key informant interviews with maternal care health workers. Informed consent was obtained from all participants. An interview guide was used to guide enquiry about perceptions of perinatal depression and health service needs. Interviews were transcribed, translated and analysed using content analysis approach. common health that self-care and of and and delivery system as crucial effectively and identified in The results of this study support plans to develop a family focused intervention for perinatal depression in Malawi addressing relationship, psychosocial and economic issues. It also highlights the importance of strengthening the health delivery system especially at primary care level where the majority of women access care in Malawi and across Sub-Saharan Africa.
of Birmingham Social deprivation as a risk factor for late presentation of proliferative diabetic retinopathy

Purpose: The aim of this study was to determine whether social deprivation is a risk factor for late presentation of patients with proliferative diabetic retinopathy and whether it affects their access to urgent laser treatment. Methods: Using a 2:1 case: control design, 102 patients referred to a UK teaching hospital as part of the UK Diabetic Retinopathy National Screening Programme were identified for the period between 1 June 2010 to 1 June 2013. Social deprivation was scored using the Index of Multiple Deprivation 2010. Additional variables considered included age, duration of disease, ethnicity, and HbA 1c at time of referral. Results: The cases comprised 34 patients referred with proliferative (grade R3) retinopathy with a control group of 68 patients with lower retinopathy grades; two control patients were excluded due to incomplete data. On univariate analysis, R3 retinopathy was associated with higher social deprivation ( P , 0.001, Mann–Whitney U -test), and with higher HbA 1c (11.5% vs 8.4%; P , 0.001, Mann–Whitney U -test). Forward stepwise multivariable analysis showed that the association of R3 retinopathy with deprivation was significant even after adjusting for HbA 1c ( P = 0.016). On univariate analysis South Asian ethnicity was also identified as being a risk factor for presentation with R3 retinopathy, but this was no longer significant when HbA 1c was adjusted for in a forward stepwise logistic regression analysis. Conclusion: In our cohort social deprivation appears to be associated with late presentation of proliferative diabetic retinopathy. Our study supports the need to target these groups to reduce preventable blindness and to identify strategies which overcome barriers to care.
Genetic algorithm based 15 level multilevel inverter with SHE PWM

This research paper describes Selective Harmonic Eliminating Pulse Width Modulation (SHEPWM) amalgamated Genetic Algorithm (GA) based asymmetrical Multi Level Inverter (MLI) (15 Level) investigated by using Field Programmable Gate Array (FPGA) for single phase inverter. Multilevel inverter (MLI) have been frequently used in industry particularly to get superior quality output voltage in terms of Total Harmonic Distortion (THD). In SHE PWM equations are capable of determining the required band of switching angles to eliminate desired value of harmonics. GA algorithms playing with band of switching angles randomly to find out best solution for the MLI. Linear feedback shift register (LFSR) has been used to find the random selection of particular switching angles from the band of switching angles. Hence, the proposed method does the capable of eliminating a huge number of specific harmonics and the output voltage results in a minimum THD value. The simulation results show that the proposed method successfully attains the global solution faster than other algorithms. The de-tailed spectrum and FPGA results are presented.
Design of CSDG MOSFET based low noise amplifier for GHZ range

In this paper we have presented a Cylindrical Surrounding Double-Gate (CSDG) MOSFET based Low Noise Amplifier (LNA) that oper-ates at frequencies from 1 GHz to 10 GHz. The designed CSDG based LNA is combination of conventional LNA with CSDG MOSFET for low noise figure at high frequencies. The CSDG MOSFET comprises of both the main and active feedback transistor. The highest gain achieved is -16 dB at 2.4 GHz. The stability factor K greater than 1 and the achieved lowest noise figure is 0.2 dB at 10 GHz. The proposed designed LNA provides the lowest noise figure at the highest frequencies compared to other conventional LNAs.
Modelling of a Grade 91 power plant pressurised header weldment under ultra super-critical creep conditions International Journal of Pressure Vessels and Piping

This paper is concerned with the creep-damage modelling of a Grade 91 pressurised header, which was observed to undergo in-service cracking in the weldments. A multi-axial creep damage model of Kachanov type, with a single state damage variable, has been implemented into finite element analysis to study the creep damage re- sponses of weldments and the sub-zones i.e. the base metal (BM), weld metal (WM) and heat-affected zone (HAZ). Material properties for each weld constituent were obtained from the results of accelerated creep tests on materials extracted from the header. Predictions of crack initiation were made for sections of the stub to header welds. This analysis was also used to estimate creep failure life of the header weldment under ultra-super-critical conditions. Further, creep crack growth behaviour was predicted based on time-dependent critical damage growth. The predicted damage distributions and failure mode of the cross-weld creep test specimens were in good agreement with the reported experimental observations. The predicted damage distributions and cracking in the header correlate reasonably well with the reported industrial observations.
Introducing Fuzzy Logic in Network Intrusion Detection System

: An intrusion detection system is a software tool used to detect unauthorized access to a computer system or network. The basic principle of intrusion detection is based on the assumption that intrusive activities are noticeably different from normal ones and thus are detectable. Many intrusion detection approaches have been suggested in the literature. Traditionally these approaches are classified into three categories: misuse detection, anomaly detection and specification-based detection. This paper describes an intrusion detection system that is being develop to demonstrate the effectiveness of anomaly based technique that utilize fuzzy logic. The anomaly-based components look for deviations from stored patterns of normal behavior. The purpose of introducing fuzzy logic is to deal with the fuzzy boundary between the normal and abnormal classes.
Indigenous and synanthropic populations of Galanthus nivalis L. in Baden-Württemberg

Galanthus nivalis L. is a widely distributed species. The boundaries of its natural area of distribution, how- ever, are fuzzy due to cultivation and naturalisation. For Germany, indigenous populations have been reported from Baden-Württemberg and Bavaria. To establish the genetic identity of the populations from Baden-Württemberg, we performed molecular phylogenetic analysis based on nuclear marker ITS and on chloroplast marker trnL-trnF spacer. In addition to that, morphometric data of indigenous and synanthropic plants were analysed. Our results indicate that the indigenes are genetically distinct from the synanthropes. Furthermore, a close relationship of the indigenes to specimens from the supposed centre of origin for the species has been suggested. Morphometrically, the identity of synanthropes and indigenes is hard to establish and contradicts findings from previous studies.
Authority-Based Conversation Tracking in Twitter

The widespread use of social networking services (SNS) and the fact that users increasingly trust the news shared by their contacts or friends over those in traditional media has significantly changed our information and communication habits. In particular, when contacts considered “opinion leaders” publish a story within their sphere of influence, their contacts/followers tend to give it more credibility than they would give the mainstream media.
On Exploiting End-User Feedback in Requirements Engineering

Requirements elicitation is a relevant research area in Requirements Engineering(RE) since elicitation is a key task that must be performed in any project [12]. Elicitation usually involves diﬀerent types of stakeholders (e.g. analysts, man-agers, users, etc.) who provide information that may turn into requirements.Over time, several elicitation techniques have been proposed to gather require-ments. But how and when end-users express their expectations about a softwareis an issue that has been mainly explored within the user experience researchcommunity [7], and it is only recently that RE is looking at it [22]. User feedbackis recognised as a source for changes in a system [6] (i.e. changes in requirements,new ones, etc.). We deﬁne end-user feedback as meaningful information provided by end-usersof widely used software applications with the purpose of suggesting improvementsto such applications (i.e. new needs, modiﬁcations, or strategic behaviours). End-user feedback in discussion forums seems to be helpful for developers in evolvingapplications. Speciﬁcally, the continuous management of fansites (e.g. blogs, dis-cussion forums, etc.) of an online game (i.e. Habbo Hotel
GNSS Limitations During Position Determination and Receiver Rerformance Testing Using Android Mobile Application

– Wide GNSS (Global Navigation Satellite System) availability has its advantages, however, in that case the system is exposed to a large number of external influences, from interference with other signals to deliberate blocking and jamming. There is also a huge increase in GNSS user number for both professional and private purposes. The technology of protection and regulation is partly behind the technological development and leaves room for undesired impacts from both natural and artificial causes. Through this paper GNSS errors are described using an android mobile application, "GNSS Analysis Tool", that allows observation of the GNSS signal characteristics.
Pro ling and Functional Analysis of Long Noncoding RNAs and mRNAs during Porcine Skeletal Muscle Development

Ya Tan Institute of Animal Genetics and Breeding https://orcid.org/0000-0003-2128-2396 Mailin Gan Sichuan Agricultural University Linyuan Shen Sichuan Agricultural University Liang Li Sichuan Agricultural University Yuan Fan Sichuan Agricultural University Ying Chen Sichuan Agricultural University Lei Chen Sichuan Agricultural University Lili Niu Sichuan Agricultural University Ye Zhao Sichuan Agricultural University Anan Jiang Sichuan Agricultural University Dongmei Jiang Sichuan Agricultural University Shunhua Zhang Sichuan Agricultural University Li Zhu (  zhuli7508@163.com ) Sichuan Agricultural University
Complex Event Processing for Decision Support in an Airport Environment

— A new approach is proposed to the surveillance of Security and Safety occurrences concerning mobile objects in an airport environment, in particular to monitor aircrafts, vehicles and staff at the manoeuvring area for all weather conditions. A middleware platform receives localization information from the different mobile objects in the airport and merges that information through data fusion in the platform. The system outputs are shown in a high-resolution Graphical-User interface, providing a collaborative environment with the relevant information to the airport stakeholders. The outputs can be used by the stakeholders to take decisions on the best way to improve security and safety and also on the optimization of airport operational procedures in compliance with existing business rules. In this paper, the proposed system architecture follows an event-driven approach based on streams of occurrences processed in real-time. Therefore, it is suited for decision support. We will illustrate our approach by monitoring events occurred in an airport environment.
Effect of the Aeration Strategy on NOB Suppression in Activated Sludge and Biofilm in a Hybrid Reactor with Nitrification/Denitrification

The purpose of the study was to analyse the impact of aeration strategies defined by the changes in the duration of aerated sub-phases, the ratio between non-aerated and aerated sub-phase times (R), and dissolved oxygen concentrations (DO) on the suppression of nitrite-oxidizing bacteria (NOB) in activated sludge and biofilm developing in a hybrid reactor with nitrification/denitrification. The primary factor causing NOB suppression both in biofilm and in activated sludge was an increase in the R-value (from 0 to 1/4 and from 1/4 to 1/3). After reducing the DO from 3 to 2 mg O2/L, there were no changes in the frequency of NOB occurrence, and no reduction in the nitrite oxidation rate was recorded. The abundance of Comammox bacteria was considerably affected by the change from continuous to intermittent aeration. Activated sludge showed a substantial increase in the quantity of clade A and B, whereas the quantity considerably decreased in biofilm.
GC/MS ANALYSIS, ANTISALMONELLAL POTENTIAL OF METHANOL LEAF EXTRACTS OF TRISTEMMA MAURITIANUM AND EFFECTS ON HEMATOLOGICAL PARAMETERS ON WISTAR RATS INFECTED WITH SALMONELLA TYPHI International Journal of Pharmacy

Typhoid fever remains a marked problem of public health in the world especially Africa and Asia. This work aimed to evaluate the antisalmonellal potential of extracts and fractions from Tristemmamauritianum . The microdilution technique was used for MIC and MBC determination whereas GC/MS was used to identify some components of the methanol extract. This extract was tested in vivo against salmonella-induced typhoid in rats. Among crude extracts, the methanol extract showed the better MICs ranging from 96 to 192 µg/ml. In vivo , the activity of the methanol extract was comparable to the one of oxytetracycline since both at the tested doses were able to heal infected rats. The hematological parameters showed an increase of WBC and the decrease of RBC and differentials in non treated groups’. From GC/MS 11 compounds were identified using NIST library. The results of this work provide the baseline information for the possible usage of Tristemmamauritianum to treat typhoid fever and others salmonellosis.
SUMO Modiﬁcation of Huntingtin and Huntington’s Disease Pathology

Huntington’s disease (HD) is characterized by the accumulation of a pathogenic protein, Huntingtin (Htt), that contains an abnormal polyglutamine expansion. Here, we report that a pathogenic fragment of Htt (Httex1p) can be modiﬁed either by small ubiquitin-like modiﬁer (SUMO)–1 or by ubiquitin on identical lysine residues. In cultured cells, SUMOylation stabilizes Httex1p, reduces its ability to form aggregates, and promotes its capacity to repress transcription. In a Drosophila model of HD, SUMOylation of Httex1p exacerbates neurodegeneration, whereas ubiquitination of Httex1p abrogates neurodegeneration. Lysine mutations that prevent both SUMOylation and ubiquitination of Httex1p reduce HD pathology, indicating that the contribution of SUMOylation to HD pathology extends beyond preventing Htt ubiquitination and degradation. HD is a dominant neurodegenerative disorder caused by the expansion of a polyglutamine [poly(Q)] repeat in Htt ( 1 , 2 ). In HD and other poly(Q) diseases, mutant proteins or pathogenic poly(Q) Because ethical restrictions limit in vivo studies of the human hemato-lymphoid system, substitute human to small animal xenotransplantation models have been employed. Existing models, however, sustain only limited development and maintenance of human lymphoid cells and rarely produce immune responses. Here we show that intrahepatic injection of CD34 (cid:1) human cord blood cells into conditioned newborn Rag2 (cid:4) / (cid:4) (cid:5) c (cid:4) / (cid:4) mice leads to de novo development of B, T, and dendritic cells; formation of structured primary and secondary lymphoid organs; and production of functional immune responses. This provides a valuable model to study development and function of the human adaptive immune system in vivo. Biomedical research in humans is restricted largely to in vitro assays that lack the com-ponents and complexity of a living organ-ism. To overcome this limitation, substitute in vivo models have been developed in which human hematopoietic cells and tis-sues are transplanted into mice that are compromised in their capacity to reject xenogenic grafts. Engraftment was first reported after transfer of mature human peripheral blood leukocytes in severe combined immunodeficient mice (hu PBL-SCID mice) 1 ) and transplantation of blood-forming fetal liver cells, fetal bone, fetal thymus, and fetal lymph nodes in SCID mice (SCID-hu mice) 2 , 3 ). Subse-quently, some level of human hematopoietic development was achieved by transplantation of blood-forming cells in NOD/SCID, NOD/SCID , or
Edinburgh Research Explorer Residual inequity

: Energy policies and public health are intimately intertwined. In New York City, a series of policies, known as the Clean Heat Program (CHP), were designed to reduce air pollution by banning residual diesel fuel oils, #6 in 2015 and #4 by 2030. This measure is expected to yield environmental and public health beneﬁts over time. While there is near-universal compliance with the #6 ban, a substantial number of buildings still use #4. In this paper, geographic analysis and qualitative interviews with stakeholders were used to interrogate the CHP’s policy implementation in Northern Manhattan and the Bronx. A total of 1724 (53%) of all residential residual fuel burning buildings are located in this region. Stakeholders reﬂected mostly on the need for the program, and overall reactions to its execution. Major ﬁndings include that government partnerships with non-governmental organizations were effectively employed. However, weaknesses with the policy were also identiﬁed, including missed opportunities for more rapid transitions away from residual fuels, unsuccessful outreach efforts, cost-prohibitive conversion opportunities, and (the perception of) a volatile energy market for clean fuels. Ultimately, this analysis serves as a case study of a unique and innovative urban policy initiative to improve air quality and, consequently, public health.