Miracle-dz/UniFAR-FTUs huggingface dataset:
QR Code Card Media on Science Learning to Overcome Misconception of Elementary School Student

The education development has entered the Literacy Acceleration era in The Knowledge Age. Learning media innovation plays an important role for students in the development of technology as a learning medium, particularly in the usage of technology-based learning media. During the COVID-19 epidemic, many problems have arisen connected to online learning, one of which is student misconceptions, especially in science material, in the high class of Keboromo elementary school. This study aims to describe the need for developing QR Code-based learning media used by educators and students today, which can be used at home to support students' understanding and overcome misconceptions. According to Borg & Gall, research and development involves various processes. This study is limited to the first stage, which is the research and information collecting stage. The research subjects for this need analysis were 3 educators and 8 students representing one elementary school, namely Elementary School of Keboromo. Data collection techniques in this study using interviews. An interactive model is used in the data analysis technique, including processes such as data reduction, data presentation (data display), and conclusions drawing or verification. The findings of this study show that in order to overcome misconceptions in science subject learning, educators and students require technology-based media designs that are simple to use and accessible via smartphones or other devices. As a result, students will be more efficient with their time, more practical with their knowledge, and the material students receive will be more focused.
Worldwide Variation in Cochlear Implant Candidacy

Background: The aim of this study was to find out how candidacy criteria have evolved differently across the globe. Methods: Candidacy criteria and outcome measurements applied in 19 HEARRING clinics were analyzed. Results: Candidacy criteria vary between clinics. Overall, both bilateral implantation and cochlear implantation in patients with single-sided deafness are becoming more frequent. Conclusion : Standardized outcome measurement instruments need to be applied to provide access to the hearing world to all patients with hearing loss who would benefit from cochlear implantation.
The Role of Kynurenine Pathway and NAD+ Metabolism in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a serious, complex, and highly debilitating long-term illness. People with ME/CFS are typically unable to carry out their routine activities. Key hallmarks of the disease are neurological and gastrointestinal impairments accompanied by pervasive malaise that is exacerbated after physical and/or mental activity. Currently, there is no validated cure of biomarker signature for this illness. Impaired tryptophan (TRYP) metabolism is thought to play significant role in the pathobiology of ME/CFS. TRYP is an important precursor for serotonin and the essential pyridine nucleotide nicotinamide adenine dinucleotide (NAD+). TRYP has been associated with the development of some parts of the brain responsible for behavioural functions. The main catabolic route for TRYP is the kynurenine pathway (KP). The KP produces NAD+ and several neuroactive metabolites with neuroprotective (i.e., kynurenic acid (KYNA)) and neurotoxic (i.e., quinolinic acid (QUIN)) activities. Hyperactivation of the KP, whether compensatory or a driving mechanism of degeneration can limit the availability of NAD+ and exacerbate the symptoms of ME/CFS. This review discusses the potential association of altered KP metabolism in ME/CFS. The review also evaluates the role of the patient’s gut microbiota on TRYP availability and KP activation. We propose that strategies aimed at raising the levels of NAD+ (e.g., using nicotinamide mononucleotide and nicotinamide riboside) may be a promising intervention to overcome symptoms of fatigue and to improve the quality of life in patients with ME/CFS. Future clinical trials should further assess the potential benefits of NAD+ supplements for reducing some of the clinical features of ME/CFS.
On-Line Identification Method for Critical Buses of Power System Voltage Stability

The parameters of an equivalent single source system were computed on-line based on bus voltages and inject currents in the adjacent regions of monitored buses,in which the equivalent loads are affected only by the loads in the surrounding grid.Based on the equivalent model,a load margin index was used to monitor the voltage stability of multi-generator systems.The new voltage stability monitoring method was simulated in the modified IEEE 50 generator test system.The simulation results show that it can identify the critical buses that are prone to voltage instability.
Structure of Odonate Assemblage in K’laja Karst Ecotourism Park, General Santos City, Philippines

Odonates are sensitive to disturbances and changes in habitat quality and integrity. However, our understanding of odonates as environmental bioindicators remains limited. This concern arises primarily from the significant data gaps in the local and global structure and distribution pattern of odonate fauna, especially in terrestrial landscapes. This study determined the assemblage and diversity attributes of odonate species in K’laja Karst Ecotourism Park, one of the few remaining natural reserves in General Santos City, Southern Mindanao. Data showed a rich and highly diverse odonate fauna with 22 species belonging to 19 genera within nine families. More than 45% of the documented odonate species were endemic to the Philippines, 89% of which were Zygopterans (damselflies). Anisopterans (dragonflies) were more abundant and species-rich, comprising 56% and 59% of the total collection, respectively, with the libellulids dominating in both respects. Several Anisopteran species thrived abundantly in open, cultivated fields, while most Zygopteran species recorded higher numbers and diversity indices in shaded habitats adjacent to the river. Findings reveal that while odonate composition and diversity remain robust, the relative distribution and proportion of Zygopteran and Anisopteran species indicate habitat alteration and degradation. Together, these data provide a basis for identifying priority areas for protection and conservation in the karst landscape.
General Roadmap and Core Steps for the Development of AI Tools in Digital Pathology

Integrating artificial intelligence (AI) tools in the tissue diagnostic workflow will benefit the pathologist and, ultimately, the patient. The generation of such AI tools has two parallel and yet interconnected processes, namely the definition of the pathologist’s task to be delivered in silico, and the software development requirements. In this review paper, we demystify this process, from a viewpoint that joins experienced pathologists and data scientists, by proposing a general pathway and describing the core steps to build an AI digital pathology tool. In doing so, we highlight the importance of the collaboration between AI scientists and pathologists, from the initial formulation of the hypothesis to the final, ready-to-use product.
study on financial literacy among college students

Financial literacy is increasingly important as it has become essential that individuals acquire the skills to be able to survive in modern society and cope with the increasing diversity and complexity of financial products and services available. Financial literacy is the ability to make informed judgments and to take effective decisions regarding the use and management of money. It enables individuals to improve their overall wellbeing and to plan for their future security. The main objective of the study is to analyse the level of financial literacy among the college students. Both the primary and secondary data has been used in this study. Knowledge on money management, savings, investments, and credit has been considered to measure the financial literacy level and students current and past manners related to same dimensions is used to measure financial behavior using questionnaire. In this study, the results were analyzed based on gender and qualification. Significant relationships were found between financial literacy and student characteristics.
Correlation analysis of vertical jump variables in male track and field athletes

Background : The purpose of this study is threefold: (1) compare differences in countermovement jump (CMJ) variables and squat jump (SJ) variables in male track and field athletes; (2) explore the correlation of Fast Twitch Fibers (FT), Effect of Pre-stretch (EP) and other variables during the CMJ in male track and field athletes; (3) explore the correlation of SJ variables in male track and field athletes. Methods : 96 male university athletes (21.25 ± 1.04 years; 71.96 ± 8.58 kg; 180.05 ± 5.66 cm) in track and field volunteered to participate in this study. They are from Capital University of Physical Education and Sports, and all athletes are above the national standard at the second level. Subjects sequentially completed 3 CMJs and 3 SJs on the force plate. Throughout the entire range of motion, the CMJ and SJ were performed with both hands on the hips. In a laboratory, all of the individuals were assessed at the same time. SPSS 25.0 (Chicago, IL, USA) was used to run independent samples t -test and Pearson correlation analysis. Results : The vertical jump displacement (VJD) ( p < 0.01), squat displacement (SD) ( p < 0.01), peak velocity (PV) ( p < 0.01), peak power (PP) ( p < 0.05), average power (AP) ( p < 0.01) were significantly higher during the CMJ than during the SJ. The peak force (PF) ( p < 0.01) was significantly smaller during the CMJ than during the SJ. The FT and EP during the CMJ were associated with low test-retest reliability (coefficient of variation (CV): 9.73–8.86%). VJD, SD, PF, PP, and AP produced high test-retest reliability (CV: 2.29–4.48%) during both the CMJ and SJ movements. The correlation results were as follows, the VJD during the CMJ was significantly related to SD, PF, PP, AP (r = 0.21, r = 0.42, r = 0.8, r = 0.69, respectively). The PF during the CMJ was significantly related to PP and AP (r = 0.87, r = 0.72, respectively). The PV during the CMJ was significantly related to PP and AP (r = 0.63, r = 0.79, respectively). During the CMJ, there were significant connections between PP and AP (r = 0.94). Except for SD showed no significant relationships and the results for the correlation of other variables were the same as CMJ during the SJ. Furthermore, the Fast Twitch Fibers (FT) during the CMJ was significantly related to PP and AP (r = 0.49, r = 0.46, respectively). The Effect of Pre-stretch (EP) during the CMJ was significantly related to PV, PP, AP and FT (r = 0.36, r = 0.24, r = 0.27, r = 0.22, respectively). Conclusions : Our results indicate that both FT and EP were highly significantly correlated with PP in CMJ, and both FT and EP were significantly correlated with AP in CMJ. In addition, FT and EP data have good reliability. It means that FT and EP may be important indicators of lower limb strength in male track and field athletes under certain conditions. This will inform the training of male track and field athletes.
Long-Term Sex-Specific Effects of Cadmium Exposure on Osteoporosis and Bone Density: A 10-Year Community-Based Cohort Study

This study explored the long-term effects of cadmium (Cd) exposure on osteoporosis incidence and bone mineral density (BMD). This retrospective cohort study included men aged ≥50 years and post-menopausal women from the 2001–2002 Korea Genome and Epidemiology Study. Participants previously diagnosed with osteoporosis were excluded. Blood Cd concentrations were measured and categorized as <0.5, 0.5–1.0, and >1.0 μg/L. BMD was measured using quantitative ultrasound. Osteoporosis was diagnosed when the T-score was ≤−2.5. Confounders that affect exposure and outcome were controlled. Osteoporosis incidence and differences in BMD (ΔBMD) were assessed until 2012. The osteoporosis incidence among 243 participants who were followed up for an average of 6.3 years was 22.2%. In all the participants, a dose–response relationship was observed between blood Cd and incident osteoporosis and ΔBMD (both p-for-trend < 0.01). After adjusting for age, sex, smoking, physical activity, body mass index, creatinine, and baseline BMD, a blood Cd concentration of >1.0 μg/L was an independent risk factor for incident osteoporosis and decrements in ΔBMD. In women, blood Cd concentrations of >0.5 μg/L increased the risk for osteoporosis. Exposure to Cd prospectively increases the risk for osteoporosis and decrements of ΔBMD, particularly in women, even in lower doses of Cd.
Zearalenone Degradation by Dielectric Barrier Discharge Cold Plasma: The Kinetics and Mechanism

In this study, dielectric barrier discharge (DBD) cold plasma was used to degrade zearalenone and the efficiency of degradation were evaluated. In addition, the degradation kinetics and possible pathway of degradation were investigated. The results showed that zearalenone degradation percentage increased with increasing voltage and time. When it was treated at 50 KV for 120 s, the degradation percentage could reach 98.28%. Kinetics analysis showed that the degradation process followed a first-order reaction, which fitted the exponential function model best (R² = 0.987). Meanwhile, liquid chromatographywith quadrupole time-of-flight mass spectrometry (Q-TOF LC/MS) was used to analyze the degradation products, one major compound was identified. In this study, the reactive species generated in cold plasma was analyzed by Optical Emission Spectroscopy (OES) and the free radicals were detected by Electron Spin Resonance (ESR). This study could provide a theoretical basis for the degradation of zearalenone to a certain extent.
Oligometastatic Prostate Cancer: Is there a Role for Surgery? A Narrative Review

Oligometastatic prostate cancer is commonly considered a transition between high metastatic and localized disease and includes a large spectrum of conditions with a polymorphic clinical behavior. The current management of these patients contemplates systemic therapy (i.e., androgen-deprivation drugs, chemotherapeutic drugs, or both treatments administered simultaneously) which have been shown to improve survival. Radiotherapy has also been introduced, into a multimodal setting, among the therapeutic treatments for patients who are defined as oligometastatic prostate cancer according to Chemohormonal Therapy Versus Androgen Ablation Randomized Trial for Extensive Disease in Prostate Cancer (CHAARTED) criteria. The role of surgical debulking in patients with oligometastatic prostate cancer has always been considered impracticable, both for a marginal therapeutic role and for the greater risk of sequelae and/or complications related to the procedure itself. Several authors have demonstrated some mechanisms by which the persistence of the primary tumor can facilitate the clinical progression of the disease itself and promote carcinogenesis, differentiation, migration, and angiogenesis in prostate cancer. From these studies emerges the hypothesis of a possible therapeutic advantage in oncological terms also for cytoreductive radical prostatectomy, in a multimodal therapy setting, compared to systemic therapy alone. The present review summarizes the main knowledge regarding the safety, feasibility, and oncological outcomes of cytoreductive radical prostatectomy in oligometastatic prostate cancer patients.
A multi-objective optimization based on genetic algorithms for the sustainable design of Warm Mix Asphalt (WMA)

ABSTRACT In this research, a methodology was developed to optimize the design of Warm Mix Asphalt (WMA) with the inclusion of three recycled materials as partial replacement of natural aggregates (NAs), namely Crumb Rubber (CR), Reclaimed Asphalt Pavement (RAP), and Recycled Concrete Aggregate (RCA). The methodological proposal is composed of 4 sections denominated: (I) environmental module, (II) economic module, (III) decision-support module, and (IV) results report module. Initially, a Life Cycle Assessment (LCA) is carried out to quantify the environmental impacts associated with WMA production. Similarly, in the second module, a Life Cycle Costing (LCC) is performed to estimate the financial investment required by the process under evaluation. Meanwhile, a computational model based on genetic algorithms (GAs) is created in the decision-support module to execute multi-objective optimization (minimization of costs and contaminating potential). In the last module, the more accurate WMA designs are presented employing a Pareto front, ternary plot, composition pie chart, and statistical analysis of the influence of the CR, RAP, and RCA on the validation criteria. This study concludes that even under long hauling distances and huge prices, it is possible to design WMA with CR, RAP, and/or RCA additions that form sustainability benefits compared to conventional WMA.
Novel miniaturised and highly versatile biomechatronic platforms for the characterisation of melanoma cancer cells

There has been an increasing demand to acquire highly sensitive devices that are able to detect and characterize cancer at a single cell level. Despite the moderate progress in this field, the majority of approaches failed to reach cell characterization with optimal sensitivity and specificity. Accordingly, in this study highly sensitive, miniaturized-biomechatronic platforms have been modeled, designed, optimized, microfabricated, and characterized, which can be used to detect and differentiate various stages of melanoma cancer cells. The melanoma cell has been chosen as a legitimate cancer model, where electrophysiological and analytical expression of cell-membrane potential have been derived, and cellular contractile force has been obtained through a correlation with micromechanical deflections of a miniaturized cantilever beam. The main objectives of this study are in fourfold: (1) to quantify cellmembrane potential, (2) correlate cellular biophysics to respective contractile force of a cell in association with various stages of the melanoma disease, (3) examine the morphology of each stage of melanoma, and (4) arrive at a relation that would interrelate stage of the disease, cellular contractile force, and cellular electrophysiology based on conducted in vitro experimental findings. Various well-characterized melanoma cancer cell lines, with varying degrees of genetic complexities have been utilized. In this study, two-miniaturized-versatile-biomechatronic platforms have been developed to extract the electrophysiology of cells, and cellular mechanics (mechanobiology). The former platform consists of a microfluidic module, and stimulating and recording array of electrodes patterned on a glass substrate, forming multi-electrode arrays (MEAs), whereas the latter system consists of a microcantilever-based biosensor with an embedded Wheatstone bridge, 5 and a microfluidic module. Furthermore, in support of this work main objectives, dedicated microelectronics together with customized software have been attained to functionalize, and empower the two-biomechatronic platforms. The bio-mechatronic system performance has been tested throughout a sufficient number of in vitro experiments.
Secured and Deterministic Closed-Loop IoT System Architecture for Sensor and Actuator Networks

Sensors, actuators, and wireless communication technologies have developed significantly. Consequently, closed-loop systems that can be monitored and controlled by devices in IoT environments, such as farms and factories, have emerged. Such systems are realized by means of cloud-level and edge-level implementations. Among them, with a model that generates real-time control decisions at the cloud level, it might be difficult to ensure the determinism of real-time control due to communication overheads. In addition, if the actuator is remotely controlled at the cloud level, it is difficult to secure control safety against external hacking or device malfunction. Herein, we propose a system architecture that can fulfil real-time performance and safety requirements with two commonly used devices, Field Edge Unit (FEU) and Current Sensing Tag (CST), in a closed-loop IoT environment. By using these devices, we designed a special architecture that can be commonly used in various closed-loop sensing and actuating applications. In this study, the proposed architecture is evaluated by applying it to a smart farm application.
PENGARUH CUSTOMER ENGAGEMENT TERHADAP BRAND LOYALTY DENGAN VARIABEL MEDIASI BRAND ATTACHMENT DAN CUSTOMER TRUST

Traveloka melakukan interaksi dengan pelanggan melalui media sosial untuk meningkatkan customer engagement yang dapat mempengaruhi brand loyalty. Tujuan dari penelitian ini adalah untuk mengetahui seberapa besar pengaruh dari customer engagement terhadap brand loyalty dengan menggunakan variabel mediasi brand attachment dan customer trust. Digunakan metode kuantitatif untuk menguji hubungan antar variabel-variabel yang membentuk model persamaan struktural yaitu dengan menggunakan data empirik yang diambil melalui survey dangan lima skala linkert. Convenience sampling dengan teknik non-probability sampling digunakan terhadap 215 sampel responden dengan menggunakan kuesioner dengan 21 item pertanyaan yang disebarkan secara online dengan google form yang berasal dari pelanggan Traveloka Indonesia. Perangkat lunak yang digunakan untuk melakukan serangkaian pengujian didapatkan hasil seluruh variabel sudah valid dan reliabel, model penelitian memenuhi kriteria kecocokan. Enam hipotesis yang diajukan terdapat lima hipotesis diterima dan satu hipotesis ditolak. Variabel mediasi yang memiliki pengaruh paling besar terhadap brand loyalty adalah customer trust. Terdapat pengaruh tidak langsung pada customer engagement terhadap brand loyalty yaitu melalui brand attachment dan customer trust. Untuk meningkatkan brand loyalty, selain meningkatkan upaya customer engagement diperlukan juga untuk meningkatkan brand attachment dan customer trust. Penelitian selanjutnya diharapkan untuk mengeksplorasi variabel lain yang menyangkut dengan kinerja pemasaran yang berdampak pada penjualan seperti purchase decision dan repurchase intention. Implikasi dari penelitian ini menguatkan teori cara meningkatkankan pengaruh customer engagement terhadap brand loyalty menggunakan variabel mediasi brand attachment dan customer trust.
Multi-Scale translation method from SAR to optical remote sensing images based on conditional generative adversarial network

ABSTRACT Synthetic aperture radar (SAR) has all-weather and all-day observation capabilities and a certain ability to penetrate the surface; therefore, it has unique advantages in many aspects, which other remote sensing methods cannot achieve. However, owing to imaging principles, the interpretation of SAR images is complicated. Therefore, converting SAR images into optical remote sensing images is one method of SAR image interpretation. Therefore, this paper proposes an improved conditional generative adversarial network (cGAN) that includes a generator based on the encoder-decoder structure of the swin transformer feature extraction module. The generator uses a spatial pyramid structure and multi-scale depth feature extraction structure to extract the SAR image features at different scales. A multi-scale discriminator was used to discriminate images on different scales. The introduction of feature matching loss makes the discriminator’s feedback to the generator richer and uses perceptual loss based on VGGNet to evaluate the image quality in depth. A series of experiments verified the effectiveness of the method in this study and proved the potential of the transformer structure in the field of SAR image translation. The method presented in this paper has obvious advantages and can translate SAR images into optical remote sensing images.