Miracle-dz/UniFAR-FTUs huggingface dataset:
The development of on-chip THz time-domain spectroscopy

Since the development of efficient THz sources, THz-TDS has been proved to be a promising tool to probe directly the intermolecular modes, rotational motion and intermolecular vibrations of molecules in a variety of chemicals capable of extracting useful spectroscopic information. In this thesis, an on-chip spectroscopy system based on coplanar waveguide (CPW) technology has been designed, optimised and tested, in order to probe spectral features of overlaid polycrystalline materials. As proof of principle, this system was used to recover the THz spectra of α-lactose monohydrate, observing spectral features at ~ 0.53 THz and ~ 1.37 THz. A significant frequency shift in the 1.37 THz feature was observed when the on-chip spectroscopy measurements were performed over a variable temperature range of (~ 6-293 K). Spectral features obtained from the on-chip system were also compared to those obtained from a free-space THz-TDS system to highlight the benefits of using an on-chip system over free space THz-TDS. A theoretical model developed using Ansoft HFSS tool was then used to optimise device design parameters in the second generation of CPW devices. In doing so, the bandwidth of the system was enhanced from ~ 0.42 to 1.6 THz and a much higher frequency resolution of (~ 2 GHz) was obtained compared to that of the first-generation CPW devices (~ 55 GHz) with the modified device design of second generation devices. Branching waveguide systems (THz Y-splitter and coupler) were also simulated, fabricated and measured in order to investigate THz pulse splitting in branching waveguides. These systems allow the measurement of both a sampled and reference pulse. During these measurements, the splitting of the THz pulses propagating in an on-chip THz system was also demonstrated for the first time.
Amoeboid-like migration ensures correct horizontal cell layer formation in the developing vertebrate retina

Migration of cells in the developing brain is integral for the establishment of neural circuits and function of the central nervous system. While migration modes during which neurons employ predetermined directional guidance of either preexisting neuronal processes or underlying cells have been well explored, less is known about how cells featuring multipolar morphology migrate in the dense environment of the developing brain. To address this, we here investigated multipolar migration of horizontal cells in the zebrafish retina. We found that these cells feature several hallmarks of amoeboid-like migration that enable them to tailor their movements to the spatial constraints of the crowded retina. These hallmarks include cell and nuclear shape changes, as well as persistent rearward polarization of stable F-actin. Interference with the organization of the developing retina by changing nuclear properties or overall tissue architecture hampers efficient horizontal cell migration and layer formation showing that cell-tissue interplay is crucial for this process. In view of the high proportion of multipolar migration phenomena observed in brain development, the here uncovered amoeboid-like migration mode might be conserved in other areas of the developing nervous system.
MOTHER’S EMPLOYMENT, CHILD CARE USE AND COGNITIVE DEVELOPMENT IN EARLY CHILDHOOD

This paper aims to analyze the effects of mother’s employment and non-parental child care on cognitive development in early childhood. Investment in the development of children at early rather than later ages provides higher returns in terms of labor market outcomes. Thus, decision making process of primary care givers are extremely important at this period. A nationally representative longitudinal data for the United States of America is used in this paper. Hybrid production function for the cognitive development is estimated within a dynamic framework using a two-step system Generalized Method of Moments estimator. The results show that more hours of center-based care significantly increase cognitive achievement and this holds true when center-based care is defined as fullor part-time. Furthermore, both a high quality home environment and a high quality out-of-home child care improve a child’s cognitive development while there is no statistically significant impact of maternal work hours.
LOCALIZATION OF CA ++-ACTIVATED ADENOSINE TRIPHOS- PHATASE ACTIVITIES TN THE TRANSITIONAL EPITHELIUM OF THE RABBIT

The localization of Ca++-activated adenosine triphosphatase (Ca++-ATPase) activity was studied ultracytochemically in the transitional epithelium of the rabbit urinary bladder. The superficial cells contained two types of filaments, measuring 4-5 nm and 6-10 nm in diameter respectively. The former 4-5 nm filaments are considered to correspond to actin filament, but the latter 6-10 nm filaments seem to be composed of a little thinner, around 7 nm, filaments and a little thicker, around 10 nm, filaments. The thicker ones are located predominantly in the vicinity of the desmosomes and are inserted into them and are considered to be tonofilaments. The dense globular particles of the reaction products showing Ca++-ATPase activity were observed in the filament-rich field. These products lay superimposed on the filaments or immediately lateral to them. Tonofilaments were, however, not positive for the activity. These results suggest that the 4-5 nm and probably 7 nm filaments also, but not 10 nm tonofilaments, are the contractile proteins. The deposits of the reaction products may correspond to the site of the cross-bridge of the contraction system. Functionally these filaments might serve for the change of the cell shape during the contraction-distension cycles of the urinary bladder.
Information integration for graph databases

With increasing interest in querying and analyzing graph data from multiple sources, algorithms and tools to integrate different graphs become very important. Integration of graphs can take place at the schema and instance levels. While links among graph nodes pose additional challenges to graph information integration, they can also serve as useful features for matching nodes representing realworld entities. This chapter introduces a general framework to perform graph information integration. It then gives an overview of the state-of-the-art research and tools in graph information integration.
Uniting qualitative design research and quantitative market research: a case example of userdriven innovation in the Dutch health club industry

In the current market, the focus is more and more on building long-term relationships with clients in which value is created, communicated and delivered. This also means developing a new customer relationship focus that goes beyond the consumer orientation that has thus far dominated the practice of marketing. In a user-driven approach, the basis is no longer the product range, the world of the manufacturer or supplier, but rather the experience of the user. This has implications not only for manufacturers and service providers, but also for marketeers and market researchers. We feel that the most commonly used methods and techniques do not answer to the new demands of the market. We have therefore adapted emerging generative user research methods from the field of design as a basis for a truly user-driven market approach. As part of the Fitness in Motion project -a programme aimed at helping the health club industry develop a stronger customer orientation- we applied Contextmapping, a generative technique that has already proved its worth in the world of industrial product development and interaction design.
Pyridoxine-dependent status epilepticus diagnosed during infancy

Pyridoxine dependence is a very rare inborn error of metabolism. The disorder devel-ops mainly during the early neonatal period, and cases diagnosed in infants are even rarer. We herein report a case of a 77-day-old boy with status epilepticus diagnosed with pyridoxine dependence. On day 2 after birth, the boy required respiratory management after en-tering a partial convulsive state. The convulsions did not respond to phenobarbitals and were temporarily controlled by continuous intravenous administration of midazolam. Sub-sequently, partial seizures occurred frequently, and the patient was observed under treatment with oral phenobarbital and phenytoin, and intravenous midazolam. However, at 65 days of age, partial convulsions of the right upper and lower limbs lasting for one minute oc-Corresponding Abstract Published online: July 4, 2011 curred episodically in clusters every few to ten minutes. A high dose of phenobarbital was administered and the blood concentration increased to 42 μ g/ml, but convulsions were not controlled. At 77 days of age, when 100 mg of pyridoxine was slowly injected intravenously during electroencephalography, the background activity flattened and spikes disap-peared. Pyridoxine dependence was diagnosed and all antiepileptic agents were dis-continued. Oral administration of pyridoxine at 10 mg/kg/day was started and seizures no longer occurred. Pyridoxine dependence is a treatable inborn error of metabolism. To ob-tain a diagnosis of pyridoxine dependence, trial administration of pyridoxine is essential, and the pyridoxine test for a definitive diagnosis should also be conducted in cases of status epilepticus during infancy.
Analysis of Adaptation Capacity in the Context of Building Resilience to Threats– Local Level

Abstract Adaptability is the base in the concept of adaptation, it activates social adaptation, have an impact on susceptibility reduction and on increasing of resilience to threats in communities at the local level. What is more, it allows to strengthen the economic opportunities of the society, uninterrupted social communication, social education process and social capital building, which is necessary in resilience building to threats. The subject of research in this article is adaptation capacities of the community at the local level. The main goal of the research was to identify the essence of adaptive abilities in building resilience to threats in communities at the local level. The research problem took the form of the following question: How important is adaptability in building resilience to threats in communities at the local level?
NETWORK BEST PRACTICES AND EVOLUTION OF ORGANIZATIONAL CAPABILITIES

The aim of this paper is to study the impact of the alliance/network best practices on the evolution of internal organizational capabilities. The core idea is that kind of best practices – at the domestic and international level – represent different superior abilities to exploit and to explore collaborative know–how (Simonin, 1997) which enhance inter–firm learning processes, with a positive effect on the renewal of capabilities and products. The empirical section proposes the most interesting issues about three case studies concerning well known international/multinational firms. Each case study was developed by using qualitative methods (Eisenhardt, 1989; Yin, 2003) and satisfies all main validity parameters.
PRESENT BIAS, FINANCIAL SOURCES AND PRODUCTIVE VARIABLES: EVIDENCE OF A GROUP OF MILK PRODUCERS IN HERMOSILLO, SONORA

— The aim of this work is to relate the present bias (pb) with financial sources choice and productive variables of a group of milk producers in Hermosillo, Sonora. A sample of 53 milk producers (8 women and 45 men) with an age range of 29 to 73 years was intentionally selected. Through a socio-economic, productive and financial questionnaire and a choice test, it was found that: (a) the 51% of the producers choose informal sources, of which 72% presented pb; (b) a total milk production of 7,128 liters per day was registered, where 59% of the volume produced corresponded to pb producers; and (c) statistically significant differences were found between the pb and the type of financial source, but not between pb and production. The results in the present investigation not only reflect the high prevalence of pb in the producers, but also have inconsistency in their preferences, which may affect the development of the production unit.
Social Factors Affecting on Sustainable Gas Consumption ( Household Subscribers of Mazandaran Province )

*Corresponding Author: Sadegh Salehi E-mail: s.salehi. umz@gmail.com كچ ی :هد و یگناخ زاگ فرصم ندوب رادیاپ نازیم یسررب ،رضاح قیقحت ماجنا زا فده یعامتجا لماوع نییعت رثؤم هس . تسا نآ رب لاؤس . دش حرطم قیقحت نیا رد 1 لمع ) هزادنا هچ ات هناخ رد زاگ فرصم تتسا رادیاپ 2 ) یعاتمتجا لتماوع رثؤم زاگ فرصم رب هب ناونع رادیاپ لمع کی مدتک دتنا 3 ییاتهرااهار هتچ ) یم زاگ فرصم رد یرادیاپ شیازفا یارب اتیبدا رورم زا سپ درک هئارا ناوت ،رادیاپ فرصم و رادیاپ هعسوت میهافم و قیقحت هتسدود لتماوع زا هتب ناوتنع پ ی ش ب ی ن هدننک ی دتیاپ فرتصم ارتیییت یاته ور زا . دندتش شتیرعت زاتگ را هداد یروادرگ رازبا . دش هدافتسا شجنس یارب شیامیپ . تتسا همانتشسرپ ،اته هب روظنم اتبنورک اتفلآ و یروص رابتعا ،هزاس رابتعا زا ییایاپ و ییاور یسررب اتب هتک دتندوب ناردتنزام ناتسا یگناخ نیکرتشم ،یرامآ هعماج . دش هدافتسا هویتش زا هدافتسا هتنومن گ تی ر ی هتشوخ ا ،کیتامتتسیس یفداتصت ی 430 رتفن هب ناونع هتفای . دندش باختنا یرامآ هنومن نازتیم هتک داد ناتشن قیقحت یاه زاگ فرصم ندوب رادیاپ لتی حت ماتجنا زا ستپ . دراد رارتر تسوتم حطس رد اتب قباتطم . دش هتفرگ رظن رد زاگ رادیاپ فرصم یارب دعب هس یفاشتکا لماع زا لصاح جیاتن لدم زاس ی یباتیزرا ،یراتخاس فرتصم ناگدتننک زا ینابیتتشپ زاتگ فرتصم یفیصوت یاهراجنه و زاگ تکرش سوت امدخ ورف زا سپ نیرتشیب ثأت ی ر زرا ،زاگ فرصم رد ینمیا دعب رب ار و یتتسیز یتحم یاته زاگ فرصم شناد ،یفیصوت یاهراجنه ،تیاهن رد و فرصم رد یهاگآ دعب رب زرا اجنه و یتسیز یحم یاه نیرتشیب زاگ فرصم یزیوجت یاهر ثأت ی ر ار فرصم دعب رب هنلاوئسم زاگ ثأت ی ر دنتشاد .
IMPLEMENTATION OF AN ACTIVE DAMPING SYSTEM TO REDUCE HARMONIC VIBRATIONS IN A 3DOF PHYSICAL MODEL

This paper describes the work for a real implementation of an active damping system to reduce harmonic vibrations in a plane frame physical model with 3 degrees-of-freedom. For this purpose, it is suggested the use of an active mass damper commanded by a derivate controller which has the effect of increasing the modal damping coefficients in correspondence with a specific gain value. This control gain, as well as the system stability, was evaluated using the root-locus technique. The efficiency of the proposed control system to achieve pre-defined damping ratios was verified experimentally, by analyzing the free decay responses of the system after being excited at resonant frequencies.
The Journal of Toxicological Sciences

Hexavalent chromium [Cr(VI)] is a carcinogenic heavy metal that is reduced to intermediate oxidation states, such as Cr(V) and Cr(IV), in the process of forming stable Cr(III) forms; it is these intermediate forms that are thought to be responsible for much of the DNA damage and mutations that are induced by Cr(VI). Metallothionein (MT), a heavy metal-binding protein, is induced by zinc and other heavy metals and protects cells from the toxic effects of these metals by sequestering them. MT cannot bind Cr, but by scavenging reactive oxygen species through its cysteine residues, it may act as a protective factor against Cr(VI)-induced DNA lesions by reducing Cr(VI) directly to Cr(III), thereby avoiding the creation of the toxic intermediates. Here, we showed that Zn deficiency decreased MT expression in BALB/3T3 clone A31-1-1 cells and caused them to become highly susceptible to Cr(VI)-induced transformation. To obtain Zn-deficient cultures, cells were cultured in medium supplemented with 10% Chelex®100 chelating resin-treated FBS. The increase in susceptibility to transformation was abolished by culturing the cells with supplemental Zn (50 μM). Previously, we reported that Cr(VI) inhibits MT transcription by preventing the zinc-dependent formation of a complex of metal response element-binding transcription factor-1 (MTF-1) and the co-activator p300. Our results suggest that the carcinogenicity of Cr(VI) is enhanced by MTF-1 dysfunction.
Estrogen withdrawal and replacement differentially target liver and adipose tissues in 1 female mice fed a high-fat high-sucrose diet. Impact of a chronic exposure to a low-dose 2 pollutant mixture. 3 the French ''Ministère de l'Education

HAL is a multi-disciplinary open access archive for the deposit and dissemination of scientific research documents, whether they are published or not. The documents may come from teaching and research institutions in France or abroad, or from public or private research centers. L’archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d’enseignement et de recherche français ou étrangers, des laboratoires publics ou privés. Estrogen withdrawal and replacement differentially target liver and adipose tissues in 1 female mice fed a high-fat high-sucrose diet. Impact of a chronic exposure to a low-dose 2 pollutant mixture. 3 the French ”Ministère de l’Education Benoit Julien, Claudie Pinteur, Nathalie Vega, Hubert Vidal, Danielle Naville, Brigitte Le Magueresse-Battistoni
Emotional Adjustment in Couples During and After a Failed IVF Procedure: A Systematic Review

This review aims to access the emotional setbacks and changes faced by couple who start with the IVF treatment and face a negative outcome after the treatment. It systematically analyses the level of anxiety faced by the couple before, during and after the IVF treatment cycles. Studies show that unsuccessful treatment raised the couple’s anxiety level and the levels of negative emotions, which showed significant presence even after consecutive unsuccessful cycles. Further findings indicated that unsuccessful IVF couples reported more emotional distress relative to those whom treatment had worked and females in particular experienced more psychosocial stress as compared with males. Couples who had at least one child prior to IVF treatment experienced greater emotional distress at follow-up. These couples felt less supported by the IVF Unit staff and were less satisfied with the counseling they received. The results highlighted the importance of post-treatment counseling when treatment is unsuccessful.
Accuracy of both virtual and printed 3-dimensional models for volumetric measurement of alveolar clefts prior to alveolar bone grafting compared to a validated algorithm

Objective: To determine the accuracy of virtual 3D and 3D printed models derived from cone-beam computed tomography (CBCT) scans for volumetric measurement of alveolar clefts prior to bone grafting study Friedman Test (p<0.05) determined differences between the volume methods (SPSS Statistics 19.0, IBM Corporation, New York). Results: Inter-observer reliability was almost perfect (ICC = 0.987). There were no significant differences between the three methods (p>0.05) although virtual 3D models were the most precise with the smallest standard deviations and confidence intervals. Conclusion: In this preliminary investigation, virtual 3D and 3D printed models were as precise as the validated computer algorithm for calculating alveolar cleft volumes prior to bone grafting but virtual 3D models were the most accurate and subject to further investigation could be a useful adjunct in clinical practice. Our results indicate that virtual 3D models generated with commercially available software are more accurate than calculating the volume using a ‘slice by slice’
A ship operation policy strategy optimisation thru multiattribute synthesis procedure based on biocide emissions from antifouling coatings

Veliki je broj cimbenika okolisa i deteriorativnih uvjeta u službi broda koji utjecu na sposobnost održanja brzine broda u određenom vremenskom periodu. Utjecaj hrapavosti oplakane povrsine iznimno je važan za poslovanje broda. Ispitivanjem utjecaja oplakane povrsine na brzinu i snagu, dokazano je da se hrapavost brodova u službi godinama stalno povecava. Stoga se smanjuje brzina, odnosno zahtijeva veca snaga za održanje izvorne brzine. Postupkom viseatributne sinteze, primijenjene kao optimizacijske metode za kreiranje projekta poslovanja broda, cija je programska aplikacija razvijena na Fakultetu strojarstva i brodogradnje u Zagrebu, razvijeni su i objedinjeni slijedeci modeli: - model porasta otpora, pomocu ITTC 1978 formule za izracunavanje dodatka na hrapavost, - ekonomski model vezan za analizu prihoda i rashoda poslovanja, - ekoloski model vezan za ispustanje biocida iz antivegetativnih premaza, - model obrade supstrata tj. oplakane povrsine vezane za radove u doku, Projektni problem definiraju tri cilja, temeljena na razlicitim kriterijima: - ekonomski kriterij (zarada- profit brodovlasnika), - ekoloski kriterij (stupanj zagađenja-dinamika izlucivanja biocida iz AV premaza, - kriterij drustvene koristi (dostupnost-maksimalni broj putovanja). Kreiranje triju ciljeva provedeno je primjenom racunalne simulacije i optimiranjem postupka održavanja povrsine trupa variranjem svih operacija ciscenja i premazivanja, vezano na performanse i ekonomske efekte, u ovisnosti o brzini broda, optimalnim intervalima dokiranja, planiranim troskovima goriva i drugih relevantnih troskova u luci i plovidbi. U programu su inkorporirane i varijable stupnja oneciscenja luka i izlucivanja toksicnih supstanci iz AV premaza kao i postupak pjeskarenja oplakane (celicne) povrsine. Izborom triju strategija, vezanih za kvantum izlucivanja biocida iz antivegetativnih premaza, rad artikulira ekoloske efekte unutar eksploatacijskog života broda. Primjenom prikazanih modela, analizirana je strategija poslovanja jednog Suezmax tankera kao primjer optimizacijske procedure s Pareto rjesenjima. Prikazani alternativni visekriterijalni program za ocjenu predviđanja poslovanja broda predstavlja unaprijeđenu metodologiju koja s dovoljnom tocnoscu može poslužiti brodovlasniku pri optimiranju strategije poslovanja. U clanku je prikazan samo ekoloski model vezan za ispustanje biocida iz AV premaza odnosno ekoloski kriterij kao jedan od ciljeva.
Impak Kitaran Harta Tanah Dalam Pasaran Perumahan

Kejayaan sebuah pembangunan projek perumahan amnya bergantung kepada keupayaan pasaranuntuk melonjakkan kadar jualan. Faktor pasaran yang kukuh dan dinamik membolehkan pasaranperumahan bertahan dari satu tempoh ke tempoh yang baru. Namun perubahan pada kitaran hartatanah (KHT) itu sendiri memberi kesan yang kuat terhadap prestasi penjualan produk harta tanah.Kertas penyelidikan ini adalah bertujuan mengimbas teori kitaran harta tanah yang berkait rapatdengan pasaran perumahan. Menerusi penganalisisan literasi ke atas kajian literatur terdahulu, iamenunjukkan bahawa KHT dilengkapi dengan pelbagai fasa. Setiap perubahan fasa pada kitaranharta tanah ini telah mewujudkan kedudukan ‘lemah’ dan ‘kukuh’ sekaligus memberikan kesanyang berbeza terhadap prestasi pembangunan dan pemasaran perumahan. Sehubungan itu, KHTsewajarnya dijadikan penanda ukur oleh para pelabur dan pemaju hartanah dalam membuatkeputusan yang telus ke atas setiap tindakan pembangunan harta tanah.