Miracle-dz/UniFAR-FTUs huggingface dataset:
Protecting Data Privacy in Cloud

Cloud is now widely used for the remote storage of data; it’s an On-demand device and computer resource configuration process. This allows users to avoid locally saving and storing data. Remote data sharing is an inexpensive and effective way to share cloud users community resources. DiffieHellman used the previous approach to protect multi-owner cloud sharing for distributed groups. In the existing system, there is a community signature shared among all group members that contributes to the middle attack. The program suggested using the LFSR-dependent correlation method, which primarily used handshake protocol to safely exchange community signature to detect the attack, to detect an attack. If the calculated value exceeds one (value>1), the community's public key is changed to avoid abuse.
The Impact Quality Management and Knowledge Management on Firm’s Performance with Competitive Advantage as a Mediating Variable

Government stimulus had been launched in the form of BMDTP or free import duty policy for this sector of industry in the year of 2008, but the result was not satisfactorily. There were several obstacles in Food and Beverage industry in Indonesia, for instances are restricted supply and variety of raw materials, production process is not adequate, labels that mentioning date of production, date of expiration, compositions are neglected and the rush of imported food and beverage which is superior in price and quality (The Indonesian Institute, 2917, HumasKemenkopdan UKM, 2016).
What does the Pandemic or the First Signs of the Formation of a New Civilization Indicate?

TAccording to the author, it is unlikely that after a pandemic, the world will begin to seriously change; humanity has not realized the reasons for what is happening. He interprets the modern situation pessimistically, as a civilization crisis caused by the completion of the semantic project of modernity. It is argued that the modernist project was implemented, giving rise not only to modern life and sociality, but also numerous problems. As a result, the main pillars on which the Art Nouveau was built changed dramatically. The author argues that a new project is needed, corresponding to the current planetary reality, new challenges of the time, new forms of sociality and development trends. The features of the new semantic project of civilization (the need to recognize the completion of the modern project, to formulate ideas that might appeal to our contemporaries), as well as the problems that stand in the way of its implementation are discussed.
PETROGENESIS AND TECTONIC IMPLICATIONS OF THE LATE PERMIAN 1 PERALUMINOUS AND METALUMINOUS MAGMATIC ROCKS IN THE MIDDLE 2 GOBI VOLCANOPLUTONIC BELT , MONGOLIA 3 4

38 39 The Mongol–Okhotsk Belt, the youngest segment of the Central Asian Orogenic Belt, formed by 40 the evolution and closure of the Mongol–Okhotsk Ocean. The oceanic closure formed two 41 volcanoplutonic belts: Selenge Belt in the north and Middle Gobi Belt in the south (in present 42 day coordinates). However, the origin and tectonic evolution of the Mongol–Okhotsk Belt in 43 general, the origin and formation age of the Middle Gobi Belt in particular, remain enigmatic. To 44 better understand the history of the magmatic activity in the Middle Gobi Belt, we conducted 45 geochemical, U–Pb geochronological, zircon Hf, whole-rock Nd isotopic analyses of volcanic 46 and plutonic rocks of the Mandalgovi suite, the major component of the Middle Gobi Belt. Our 47 results show that the Mandalgovi suite consists of (i) 265 ± 2 Ma biotite-granite; (ii) 250 ± 3 Ma 48 hornblende-granitoids; (iii) their volcanic equivalents of both: and (iv) gabbro-diorites. The 49 geochemical compositions indicate that their precursor magmas were derived from crustal 50 source. The protoliths of the biotite and hornblende-granitoids were metagraywacke and 51 metabasalt, respectively. They are characterized by positive whole-rock εNd(t) and zircon εHf(t) 52 values, indicating the molten protoliths were juvenile crust. The biotite-granites formed by 53 remelting of fore-arc sediments by ridge subduction and later hornblende-granites were 54 emplaced at an intra-oceanic arc by the subduction of the Mongol–Okhotsk Ocean. We conclude 55 that the magmatic rocks of the Middle Gobi formed in an active continental margin and/or intra56 oceanic arc setting. 57 58
Title of Project: Mindfulness-Based Cognitive Therapy for Preventing Suicide in Military Veterans

1. Purpose/Specific Aims We propose to conduct a randomized controlled trial (RCT) to test the efficacy of a psychotherapeutic intervention aimed at preventing suicidal behavior in veterans. The intervention, Mindfulness-Based Cognitive Therapy for Suicide (MBCT-S), was adapted by the present investigators from an existing evidence-based intervention for depression called Mindfulness-Based Cognitive Therapy (MBCT). The current intervention, MBCT-S, includes components specifically targeting reduction of suicidality. MBCT-S combines cognitive behavior therapy and mindfulness meditation practices into a unique, costefficient intervention that builds on the VA’s existing Safety Planning intervention for veterans at risk of suicide. It adds an innovative transitional service model which begins therapy during inpatient care and continues post-discharge.
Analysis of Resilience Situations for Complex Engineered Systems – the Resilience Holon

Improving the resilience of complex engineered and engineering systems (CES) includes planning for complex resilience situations, in which there may be multiple threats, interactions, and disruptions. One challenge in the modeling of CES is the identification of how interactions in a complex situation occur and their combined influence on CES resilience. This article presents a resilience holon that can be used to analyze complex resilience situations. It is made up of 24 elements (defining types of resilience, threats, interactions, and disruptions), which have varying importance to specific situations. Holons can be linked together hierarchically or in a network. An application of the resilience holon to a documented real-world resilience situation, widespread flooding in a city, illustrates its use. Pathways taken by threats and disruptions, as the flood effects cascaded through the city, are shown as connections between holons. The resilience holon could be used to decompose diverse resilience situations involving CES, to identify where critical vulnerability points are and how the whole resilience situation could be improved. The visual nature of the resilience holon could be used in an interactive way, allowing stakeholders to better understand the full resilience picture of CES that they use or operate.
Data Hiding under QR Code using Visual Secret Sharing and Advanced Partitioning Based on Specific Relationship

The Visual Secret Sharing is the technique in which secret information is hidden in the form image which then divided into shares and these shares are used to decrypt the secret information. The number of shares required is given by the creator of the secret. Minimum those many shares are needed in order to decrypt the secret. If a single share is missing then the secret cannot be decrypted. The Quick Response (QR) code gives quick access to the information contained in it. QR code is 2D representation of the barcode which has capability to store information and can be easily read by machine. Due to easy access to the information stored in it, it is necessary to use some encryption or other protection to the data. Proposed approach to visual secret sharing scheme divides a secret QR code into different shares. In addition, the secret message is recovered by using XOR operation of the shares. This can effortlessly be achieved with the use of smartphones or different QR scanning gadgets. Using optimal partitioning methods the decryption of the message is made difficult to the hackers giving additional security to the data. The message accuracy can be checked by comparing the original message with shared message using hashing techniques. Because the QR code are small in size and has high data storage capacity, it is also resistant to damage so that is information is not lost even if some portion of the QR code is damaged it is best image to be used in visual secret sharing. The proposed approach reduces the risk of data transmission attacks
Attack Detection within Network using Hybridization of Bisection TDE

Today the leading cause of attack is traffic distribution that affects transmission as well as network performance. Traditionally the mechanism is utilized for detecting traffic distribution is not so accurate, user friendly and also they are time consuming. Therefore in this paper a hybrid approach is used that detect attacks by eliminating replicated features. It utilizes TDE with bisection mechanism that has great attack detection rate The result of the proposed system as compared to existing system is better by the margin of 8 to 10%. The primary reason for the betterment is because of contrast enhancement and scaling factor at pre-processing and objective function overhead consideration at segmentation and classification phase. The results are shown in terms of accuracy, PSNR and MSE.
Dual functionalization of magnetic nanoparticles by electroactive molecules and antibodies for platelet antigens detection.

Ce travail de these s’inscrit dans un projet plus large qui vise a developper avec le laboratoire Ampere et l’Etablissement Francais du Sang un microsysteme capable de realiser un phenotypage plaquettaire pour le diagnostic de la thrombopenie neonatale. Ce microsysteme doit permettre d’isoler les plaquettes du sang total et de detecter les antigenes plaquettaires presents a leur surface. L’isolation des plaquettes se fera grâce a un module de magnetophorese et un module de dielectrophorese. La detection sera electrochimique. Le cœur de ce travail de these a donc consiste a developper des nanoparticules magnetiques pour le module de magnetophorese. Ces nanoparticules doivent permettre la capture specifique des plaquettes et servir de marqueur pour la detection electrochimique. Pour ce faire, des nanoparticules magnetiques ont donc ete doublement fonctionnalisees en une seule etape avec un anticorps anti-CD32 dirige contre l’antigene CD32 present a la surface des plaquettes et avec une molecule electroactive. Apres optimisation des differents parametres de greffage, les proprietes electrochimiques de ces particules ont ete caracterisees. Leurs proprietes de bioreconnaissance ont ete testees sur l’antigene purifie puis sur plaquettes entieres. Enfin la faisabilite de la manipulation des structures nanoparticules/plaquettes par magnetophorese avec des micro-aimants a ete demontree.
VHRM_A_210561 111..123

Yujiro Matsuishi Bryan J Mathis 2 Nobutake Shimojo Satoru Kawano 1 Yoshiaki Inoue 1Department of Emergency and Critical Care Medicine, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan; 2Medical English Communication Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan Background: Landiolol hydrochloride, a highly cardio-selective beta-1 blocker with an ultra-short-acting half-life of 4 minutes, was originally approved by Japan for treatment of intraoperative tachyarrhythmias. This review aims to provide an integrated overview of the current state of knowledge of landiolol hydrochloride in the management of arrhythmia in critical settings. Methods: We searched MEDLINE, EMBASE, and the Cochrane Library to retrieve relevant articles with a total of 65 records identified. Results: The high β1 selectivity (β1/β2 ratio of 255:1) of landiolol causes a more rapid heart rate (HR) decrease compared to esmolol while avoiding decreases in mean arterial blood pressure. Recently, it has been found useful in left ventricular dysfunction patients and fatal arrhythmia requiring emergency treatment. Recent random clinical trials (RCT) have revealed therapeutic and prophylactic effects on arrhythmia, and very low-dose landiolol might be effective for preventing postoperative atrial fibrillation (POAF) and sinus tachycardia. Likewise, landiolol is an optimal choice for perioperative tachycardia treatment during cardiac surgery. The high β1 selectivity of landiolol is useful in heart failure patients as a first-line therapy for tachycardia and arrhythmia as it avoids the typical depression of cardiac function seen in other β-blockers. Application in cardiac injury after percutaneous coronary intervention (PCI), protection for vital organs (lung, kidney, etc.) during sepsis, and stabilizing hemodynamics in pediatric patients are becoming the new frontier of landiolol use. Conclusion: Landiolol is useful as a first-line therapy for the prevention of POAF after cardiac/non-cardiac surgery, fatal arrhythmias in heart failure patients and during PCI. Moreover, the potential therapeutic effect of landiolol for sepsis in pediatric patients is currently being explored. As positive RCT results continue to be published, new clinical uses and further clinical studies in various settings by cardiologists, intensivists and pediatric cardiologists are being conducted.
Multi-Relational and Social-Influence Model for Predicting Student Performance in Intelligent Tutoring Systems (ITS)

Recent studies have shown that Matrix Factorization (MF) method, deriving from recommendation systems, can predict student performance as part of Intelligent Tutoring Systems (ITS). In order to improve the accuracy of this method, we hypothesize that taking into account the mutual influence effect in the relations of student groups would be a major asset. This criterion, coupled with those of the different relationships between the students, the tasks and the skills, would thus be essential elements for a better performance prediction in order to make personalized recommendations in the ITS. This paper proposes an approach for Predicting Student Performance (PSP) that integrates not only friendship relationships such as workgroup relationships, but also mutual influence values into the Weighted Multi-Relational Matrix Factorization method. By applying the Root Mean Squared Error (RMSE) metric to our model, experimental results from KDD Challenge 2010 database show that this approach allows to refine student performance prediction accuracy.
Characteristics of Subsidiary Financing Choices: The Role of Institutional Distance from Home Country

We examine how the institutional distance between home and host countries affects the characteristics of foreign subsidiary debt, including leverage and debt maturity choices, as well as cash holdings. We utilize the multidimensionality of institutional distances to examine ten different distance dimensions. We use a sample of 3,139 foreign subsidiaries operating in France and being headquartered in 44 different countries. We find that while subsidiaries’ financing choices are partially explained by standard determinants, they are also significantly impacted by different forms of institutional distance. Regarding the heterogeneity of institutional distances, results show the dominance of financial and cultural distances for leverage levels; knowledge and political distances for debt maturities; and a dominance of demographic, geographic, and political distances for cash holdings levels. Especially interesting, we find that leverage levels of subsidiaries are more, not less, levered when the parent has greater cultural distance from France. We interpret this result as consistent with parents, out of agency concerns, being less forthcoming with equity to more culturally distance subsidiaries. Culturally distant subsidiaries must contend with enhanced agency concerns of parent MNCs as well as liability of foreignness with local debt markets.
Fun Shopping: A Randomized Field Experiment on Gamification

Spotlight Gamification is an emerging digital strategy to engage users across different business domains. Gamification, defined as using game-design elements in nongaming contexts, shows great potential across domains such as education, business, and health. The significance of gamification is highlighted by a $7.17 billion global market in 2019 and is projected to reach more than $40 billion by 2024. This study examines two popular badges and leaderboards that utilize self-determination and social-comparison mechanisms to promote user engagement. We conduct a randomized field experiment (A/B testing) to quantify these effects in one of the largest shopping malls in Asia and further contrast the two games against coupons regarding various shopping outcomes. Quantitatively, badging and leaderboarding promote sales by 21.5% and 22.5% in the treatment period, respectively, whereas couponing delivers a more potent effect of 31.7%. In the posttreatment period, the gamification impacts remain significant, whereas the influence of couponing fades out. Besides, the additional analyses document the salient heterogeneous treatment effects across gender, age, and income. We also zoom in on the contrast between badges and leaderboards, showing that badging is a balanced tool for attracting the general public and leaderboarding is a double-edged sword that could encourage self-reinforcing or self-banishing. Finally, gamification encourages consumers to do more exploration, leading to significant increases in sales.
Passive forward ownership and upstream collusion

We examine the effects of passive forward ownership on the sustainability of upstream collusion. We consider a homogeneous Cournot duopoly with competing vertical chains. In one chain, the upstream firm has non-controlling partial ownership over its downstream exclusive client. We find that passive forward ownership hinders upstream collusion; the higher is the degree of ownership, the more difficult it is for upstream collusion to be sustained. The driving force behind our result is that a higher degree of passive forward ownership decreases collusive profits of the unintegrated upstream firm.
How To Build A Navy

Navies appear to organize their fleets according to a particular mathematical distribution known as a power law—but some appear to resemble that distribution more closely than others. If so, it may be that navies that more closely approximate that distribution are also using their resources more efficiently, and hence may have an advantage over those that do not.
Efficacy of pinaverium bromide in the treatment of irritable bowel syndrome: a systematic review and meta-analysis

Background: Spasmolytic agents are an attractive first line treatment option for irritable bowel syndrome (IBS). Pinaverium bromide (pinaverium) has antispasmodic effects on gastrointestinal smooth muscle and can relieve major IBS symptoms, but an up-to-date meta-analysis comparing the efficacy of pinaverium with placebo is lacking. The aim is to perform a systematic review and meta-analysis to assess the efficacy of pinaverium compared with placebo for IBS treatment. Methods: All placebo-controlled trials evaluating pinaverium for IBS treatment were included, up to October 2019. Treatment efficacy was evaluated by overall patient IBS symptoms. Individual symptoms were also evaluated. The effect of pinaverium versus placebo was expressed as standardized mean difference (SMD) and risk ratio (RR). Odds ratio (OR) and number needed to treat (NNT) were also calculated. Results: Eight studies were included for analysis. Pinaverium treatment had a beneficial effect on overall IBS symptom relief with a positive SMD of 0.64 [95% confidence interval (CI) 0.45–0.82, p < 0.0001] and a positive RR of 1.75 (1.26–2.43, p < 0.0008). No significant difference was found by publication year, gender, age, methodological quality score (MQS), or sample size. No publication bias was detected. OR was 3.43 (2.00–5.88, p < 0.0001), and NNT was 4. Pinaverium also demonstrated a beneficial treatment effect for abdominal pain, stool change, and bloating improvement or resolution. Conclusion: Pinaverium is superior to placebo for the treatment of IBS symptoms, irrespective of patient age or gender, study publication year, sample size, or MQS. The NNT in this meta-analysis is amongst the lowest for studies and meta-analyses of antispasmodics versus placebo in IBS.
The Effect of Intrathecal Injection of Dextromethorphan on the Experimental Neuropathic Pain Model

Background Peripheral glucocorticoid receptors (GRs) are altered by peripheral nerve injury and may modulate the development of neuropathic pain. Two central pathogenic mechanisms underlying neuropathic pain are neuroinflammation and N-methyl-D-aspartate receptor (NMDAR)-dependent neural plasticity in the spinal cord. Objectives This study examined the effect of the non-competitive NMDAR antagonist dextromethorphan on partial sciatic nerve ligation (PSL)-induced neuropathic pain and the spinal expression of the glucocorticoid receptor (GR). Methods Male mice were randomly assigned into a sham group and two groups receiving PSL followed by intrathecal saline vehicle or dextromethorphan (iDMP). Vehicle or iDMP was administered 8 - 14 days after PSL. The hotplate paw-withdrawal latency was considered to measure thermal pain sensitivity. The spinal cord was then sectioned and immunostained for GR. Results Thermal hyperalgesia developed similarly in the vehicle and iDMP groups prior to the injections (P = 0.828 and 0.643); however, it was completely mitigated during the iDMP treatment (P < 0.001). GR expression was significantly higher in the vehicle group (55.64 ± 4.50) than in the other groups (P < 0.001). The iDMP group (9.99 ± 0.66) showed significantly higher GR expression than the sham group (6.30 ± 1.96) (P = 0.043). Conclusions The suppression of PLS-induced thermal hyperalgesia by iDMP is associated with the downregulation of GR in the spinal cord, suggesting that this analgesic effect is mediated by inhibiting GR-regulated neuroinflammation.
Therapeutic Potential of Isoflavones with an Emphasis on Daidzein

Daidzein is a phytoestrogen isoflavone found in soybeans and other legumes. The chemical composition of daidzein is analogous to mammalian estrogens, and it could be useful with a dual-directional purpose by substituting/hindering with estrogen and estrogen receptor (ER) complex. Hence, daidzein puts forth shielding effects against a great number of diseases, especially those associated with the control of estrogen, such as breast cancer, diabetes, osteoporosis, and cardiovascular disease. However, daidzein also has other ER-independent biological activities, such as oxidative damage reduction acting as an antioxidant, immune regulator as an anti-inflammatory agent, and apoptosis regulation, directly linked to its potential anticancer effects. In this sense, the present review is aimed at providing a deepen analysis of daidzein pharmacodynamics and its implications in human health, from its best-known effects alleviating postmenopausal symptoms to its potential anticancer and antiaging properties.
Understanding the Stony Bridge between Osteoporosis and Vascular Calcification: Impact of the FGF23/Klotho axis

A relationship between osteoporosis (OP) and vascular calcification (VC) is now proposed. There are common mechanisms underlying the regulation of them. Fibroblast growth factor- (FGF-) 23 and Klotho are hormones associated with the metabolic axis of osteovascular metabolism. Most recently, it was suggested that the FGF23-klotho axis is associated with increasing incidence of fractures and is potentially involved in the progression of the aortic-brachial stiffness ratio. Herein, we discussed the potential role of the FGF23/Klotho axis in the pathophysiology of OP and VC. We want to provide an update review in order to allow a better understanding of the potential role of the FGF23/Klotho axis in comorbidity of OP and VC. We believe that a better understanding of the relationship between both entities can help in proposing new therapeutic targets for reducing the increasing prevalence of OP and VC in the aging population.