Miracle-dz/UniFAR-FTUs huggingface dataset:
Sexual Compliance in Finland: Characteristics, Associations, and Potential Consequences

Sexual compliance is predominantly defined as willingly engaging in unwanted sexual activity in the absence of partner pressure or coercion. The present study investigated the demographic characteristics of sexual compliance in a Finnish sample of 1,496 participants. Furthermore, based on previous literature, low sexual self-control (including sexual resourcefulness, sexual self-efficacy, and reasons for consenting) and high partner sexual relationship power (a proxy of covert social coercion) were investigated as explanatory models for sexual compliance. Lastly, this study investigated possible personal and relational consequences of sexual compliance. The sample, recruited through various social media platforms, consisted of individuals who were or had recently been in a committed intimate relationship. The rate in respondents peaked especially after two social media influencers shared the study invitation via their Instagram profiles, and thus, as the sample is likely biased, the generalizability of the following results is limited. Participants answered self-report measures of the above-mentioned aspects. Sexual compliance was common, with 65% of women, 37% men and 67% of participants of other genders reporting sexual compliance at least once in their current or most recent relationship. As 93% of the participants identified as women, only women were included in the subsequent analyses. Initial bivariate correlations showed that higher age, current relationship duration and education level were significantly associated with less sexual compliance in women, contradicting, and adding to previous literature. In line with the hypotheses, multiple regression analysis showed that women with less sexual resourcefulness, less sexual self-efficacy, more reasons for consenting, and higher partner sexual relationship power reported more sexual compliance. Most reported positive and negative consequences were in line with previous literature. Additionally, multiple regression analysis showed that women with less approach reasons, more avoidance reasons, less sexual resourcefulness, and less sexual self-efficacy reported more negative consequences of sexual compliance. Results on the association between covert social coercion and consequences of sexual compliance were inconclusive. The present study is, to my knowledge, the first to study sexual compliance in Finland. The results suggest that sexual compliance is a common phenomenon in Finnish committed relationships and seems to have both negative and positive consequences for the individual and the relationship in women. Additionally, the examination of sexual self-control and sexual relationship power seem to offer some insight to why Finnish women comply sexually.
NecX: Enabling Gesture Control Using the Neck

On-body sensing has been extensively explored by researches in the past decade. In this work, we present NecX, using neck as an input device. The system exploits surface Electromyography (sEMG) to detect the intensity of neck muscle. Our system captures the conducted current flowing through our sensor when the muscle is stressed
mir-361-5p inhibits glioma migration and invasion by targeting snD1

Background: Downregulation of miR-361-5p contributes to epithelial–mesenchymal transition of glioma cells. However, the relevance of miR-361-5p to migration and invasion of gliomas remains unknown. Materials and methods: The relationship between miR-361-5p and SND1 expression was analyzed in 120 human gliomas and 8 glioma cell lines by in situ hybridization, immunohis-tochemistry, and Western blot. Dual-luciferase reporter assay was used to identify SND1 as a target of miR-361-5p. The mechanisms through which miR-361-5p inhibits glioma cell migration and invasion were studied by in vitro assays. Results: miR-361-5p expression was significantly downregulated in glioma tissues and glioma cell lines, and was inversely correlated with glioma grades. However, SND1 expression was positively correlated with glioma grades and inversely correlated with miR-361-5p expression. miR-361-5p overexpression suppressed glioma cell migration and invasion through targeting SND1 and subsequently decreasing MMP-2 expression. In glioma cell lines, SND1 overexpression could partly reverse the antitumor effects of miR-361-5p. Conclusion: The findings provide evidence that miR-361-5p directly targets SND1 to degradation and then reduces MMP-2 gene transcription, thus inhibiting glioma migration and invasion. miR-361-5p is an important tumor suppressor and a novel diagnostic biomarker of glioma, and miR-361-5p and SND1 are potential therapeutic candidates for malignant gliomas.
Antimicrobial Activity of Some Medicinal Plants against Multi Drug Resistant Human Pathogens

The present study was conducted with a view to evaluate the therapeutic potentials of twenty six plant extracts traditionally used in Bangladesh against human pathogenic bacteria Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa and Proteus mirabilis by disc diffusion method. Out of twenty six plant extracts eight crude plant extracts namely Allamanda cathartica (leaf), Allium sativum (bulb), Citrus limon (fruit), Tamarindus indica (fruit), Prunus domestica (Fruit), Averrhoa carambola (fruit), Piper betle (leaf) and Terminalia arjuna (leaf) were found to exhibit potential antimicrobial properties against the isolated human clinical bacterial isolates whereas twelve plant extracts were failed to show any antibacterial activity against any of the isolates of Escherichia coli, Klebsiella pneumoniae and Pseudomonas aeruginosa followed by ten plant species in case of Proteus mirabilis . The maximum antimicrobial activity was found up to 80% in Tamarindus indica in case of Klebsiella pneumoniae, Pseudomonas aeruginosa and Proteus mirabilis isolates meanwhile it is Averrhoa carambola which exhibited maximum activity against Escherichia coli isolates. Among the plant species tested, Tamarindus indica showed the most promising result. These results demonstrate the antimicrobial potential of the plants and hence lend support for the use of them in traditional medicine. Sensitivity of the bacterial isolates was also evaluated for eight commercial antibiotic discs where most of the isolates found to develop resistance against multiple commercial antibiotics. Among the antibiotics used, ciprofloxacin was the most effective one.
COVID-19 and Ugandan SMEs: Impacts and Speed of Recovery

We document the impact of the COVID-19 shock and related economic restrictions on small and medium enterprises in Uganda using information on 3,961 firms interviewed twice since the onset of the pandemic in the country (i.e., March 2020). The surveys collected information on firms’ survival and performance right before, during, and after the first nationwide total lockdown (i.e., April-May 2020) and in the following year until May 2021, allowing for an analysis on both short-term and longer-term impacts. The data shows that whereas most of the firms had re-opened by July-August 2020 (right after the lockdown was lifted), they mostly did so at a reduced capacity and the recovery has been slow: one year after the start of the pandemic, revenues and profits are still 19% and 36% lower than in the pre-lockdown period. Part of the negative effects of the COVID-19 induced restrictions was transmitted to workers, translating to lower employment rate and lower average wages (respectively 66% and 76% of their pre-lockdown level as of May 2021).
Lineage-specific determination of ring neuron circuitry in the central complex of Drosophila

ABSTRACT The ellipsoid body (EB) of the Drosophila central complex mediates sensorimotor integration and action selection for adaptive behaviours. Insights into its physiological function are steadily accumulating, however the developmental origin and genetic specification have remained largely elusive. Here we identify two stem cells in the embryonic neuroectoderm as precursor cells of neuronal progeny that establish EB circuits in the adult brain. Genetic tracing of embryonic neuroblasts ppd5 and mosaic analysis with a repressible cell marker identified lineage-related progeny as Pox neuro (Poxn)-expressing EB ring neurons, R1–R4. During embryonic brain development, engrailed function is required for the initial formation of Poxn-expressing ppd5-derived progeny. Postembryonic determination of R1–R4 identity depends on lineage-specific Poxn function that separates neuronal subtypes of ppd5-derived progeny into hemi-lineages with projections either terminating in the EB ring neuropil or the superior protocerebrum (SP). Poxn knockdown in ppd5-derived progeny results in identity transformation of engrailed-expressing hemi-lineages from SP to EB-specific circuits. In contrast, lineage-specific knockdown of engrailed leads to reduced numbers of Poxn-expressing ring neurons. These findings establish neuroblasts ppd5-derived ring neurons as lineage-related sister cells that require engrailed and Poxn function for the proper formation of EB circuitry in the adult central complex of Drosophila. Summary: The formation of ring neurons is described from a pair of embryonic stem cells to engrailed and Poxn neuro-dependent lineage-specific determination of neural circuits in the central complex of Drosophila.
Adjuvant therapy of primary breast cancer: Consensus Conference, St. Gallen

he International Consensus Conference in St. Gallen, Switzerland, on adjuvant therapy of primary breast cancer was one of the most important scientific meetings in the field, besides the NIH Consensus Development Conference (1). It brought together about 3,000 people. The abstracts were published in the Supplement 1 of the journal The Breast. The Consensus Statements are expected to be published soon in the Journal of Clinical Oncology, while the oral reports will appear in Hans HuberÕs monograph. In general, it can be assumed that the Conference made further progress in three different directions. The first was the tendency toward better collaboration between clinical oncology and basic science, through the translational research. Until recently, the translational studies used almost exclusively the paraffin embedded material. Now it is recognized that the banking of tissue and other materials should be projected at the time of designing study protocols. It should allow the targeted research of new biological markers, concomitantly with study progression. The second direction of development was the increasing support to the welldesigned multicenter randomized studies, in accordance to the principles of Òevidence-based medicineÓ. This could allow, not only shortening the accrual time and getting the answers as soon as possible, but also influencing the quality of clinical research. The third novel direction adopted by the Conference was the recognition of the role of media, especially the Internet. Michael Baum (U.K.) emphasized the increasing responsibility of clinical
Structural dynamics of RbmA governs plasticity of Vibrio cholerae biofilms

Biofilm formation is critical for the infection cycle of Vibrio cholerae. Vibrio exopolysaccharides (VPS) and the matrix proteins RbmA, Bap1 and RbmC are required for the development of biofilm architecture. We demonstrate that RbmA binds VPS directly and uses a binary structural switch within its first fibronectin type III (FnIII-1) domain to control RbmA structural dynamics and the formation of VPS-dependent higher-order structures. The structural switch in FnIII-1 regulates interactions in trans with the FnIII-2 domain, leading to open (monomeric) or closed (dimeric) interfaces. The ability of RbmA to switch between open and closed states is important for V. cholerae biofilm formation, as RbmA variants with switches that are locked in either of the two states lead to biofilms with altered architecture and structural integrity.
Fruiting plants need to ensure that their seeds

7 Institute of Evolutionary Ecology and Conservation Genomics, University of Ulm, Albert8 Einstein-Allee 11, 89081 Ulm, Germany 9 Museum für Naturkunde, Leibniz-Institut für Evolutionsund Biodiversitätsforschung, 10 Invalidenstraße 43, 10115 Berlin, Germany 11 Smithsonian Tropical Research Institute, P.O. Box 0843-03092, Balboa, Panama 12 Institute of Organic Chemistry, Technische Universität Carolo-Wilhelmina zu Braunschweig, 13 Hagenring 30, 38106 Braunschweig, Germany 14 Escuela de Biologia, Universidad de Costa Rica, P.O. Box 11501-2060, San Pedro, Costa Rica 15 current address: Leibniz-Institut für Gewässerökologie und Binnenfischerei 16 Müggelseedamm 310, 12587 Berlin, Germany 17 *corresponding author, E-mail: simon.ripperger@gmail.com, phone: ++49 (0)3
Social construction of the elderly in Libya : perception, communication and discourse

Social Construction of the Elderly in Libya: Perception, Communication and Discourse The thesis investigates the social status of the elderly in Libya and how it is coconstructed in the way elderly fathers interact and communicate with younger sons, elderly peers, and healthcare providers. In the Libyan society in Sebha (a city in the Southern part of Libya, Arab, Muslim and Bedouin) the elderly occupies significant familial and societal roles and posts. The research sample consists of 13 elderly fathers and 16 younger sons who were employed in structured interviews. Another group of 6 elderly fathers and their 6 younger sons participated in semi-structured interviews. Naturally occurring conversations were tape-recorded between each elderly father and his younger son. The third group contains 3 groups of elderly peers whose conversations were taperecorded. Moreover, a group of 3 elderly patients and 3 younger physicians was interviewed and tape-recorded conversing separately with each other. The Conversation Analysis method (CA) supplemented by the social constructionist approach was adopted as a method of data analysis in this study. The findings reveal that elderly fathers are perceived by their younger sons as the family backbone, leader, advisor and decision maker. In contrast, elderly fathers perceive their younger sons as always independent, regardless of their (fathers and sons) health, wealth, and literacy. The findings also show that the large size of Libyan families provides a better chance for elderly fathers to live in extended families, and hence have more familial integration, interaction, and activation. The analyses of the elderly father/younger son conversations unveiled that elderly fathers talk more (timespan) than their younger sons. They also use considerable overlap and interruption to
Study of Distance-Based Outlier Detection Methods

An Outlier is an observation which is dierent from the others in a sample. Usually an anomaly occurs in every data due to measurement error. Anomaly detection is identifying anomalous data for given dataset that does not show normal behavior. Anomaly detection can be classified into three categories: Unsupervised, Supervised and Semisupervised anomaly detection. Anomaly detection is used variety of domains like fault detection, fraud detection, health monitoring system, intrusion detection. The outlier detection can be grouped into 5 main categories: statistical-based approaches, depth-based approaches, clustering approaches, distance-based approaches and density-based approaches. Distance -based methods i.e. Index-based algorithm, Nested-loop algorithm and LDOF are discussed. To reduce the false positive error in LDOF, we proposed MLDOF algorithm. We tested LDOF and MLDOF by implementing on several large and high-dimensional real datasets obtained from UCI machine repository. The experiments show that the MLDOF improves accuracy of anomaly detection with respect to LDOF and reduces the false positive error.
CMAR_A_237146 2405..2414

Jie Song * Youming Chen* Donghong He* Wenhui Tan Fang Lv Biao Liang Tingting Xia Jing Li 1,4 1Center of Digestive Endoscopy, Guangdong Second Provincial General Hospital, Guangzhou, People’s Republic of China; 2Department of Infectious Diseases, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, People’s Republic of China; 3Center for Reproductive Medicine, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, People’s Republic of China; 4Guangdong-Hongkong-Macau Institute of CNS Regeneration, Ministry of Education CNS Regeneration Collaborative Joint Laboratory, Jinan University, Guangzhou, People’s Republic of China
Structural changes and effect of denopamine on alveolar fluid clearance in hypoxic rat lungs

Terbutaline ( 2-adrenergic agonist) can increase alveolar fluid clearance (AFC) under physiologic and pathologic conditions. It is unknown whether 1-adrenergic agonists also increase AFC under pathologic conditions. The aim of this study was to investigate the effect of denopamine ( 1adrenergic agonist ) on AFC in hypoxic lung injury and the possible mechanisms involved. Hypoxic rats were exposed to 10% oxygen. 10 mol/L denopamine alone or combined with receptor antagonists, Na channel blocker, or Na/K-ATPase blocker were perfused into the alveolar space of rats exposed to 10% oxygen for 48 h. AFC and total lung water content (TLW) were measured. AFC did not change for the first 24 h but then decreased after 48h exposure to 10% oxygen. The perfusion of denopamine significantly increased AFC in normoxic and hypoxic rats. The AFCstimulating effect of denopamine lowered with amiloride (a Na channel blocker) and ouabain (a Na/K-ATPase inhibitor) by 35 and 53%, respectively. Colchicine significantly inhibited the effect of denopamine. Denopamine can increase the AFC during hypoxic lung injury in rats and accelerate the absorption of pulmonary edema.
A novel hybrid PSO/simplex algorithm for determining earthquake source parameters using InSAR observations

The paper presents a Paticles Swarm Optimization (PSO) and Simplex integrated approach to determine source parameters using InSAR data. In earthquake source parameter inversion, thereare differences in the sensitivity of different parameters to the objective function and a trade-off between the fault area and slip. We proposed that: (1) a local PSO algorithm is employed to perform a global search,(2) a 1-D Probability Desity Function (PDF) is utilized to describe the local minimum in the full parameters space, which is automatically recognized as the initial model in the Simplex algorithm inversion. The PSO/Simplex integrated approach has been successfully applied to three different earthquakes: the 2003 Bam (Iran) earthquake (strike-slip), the 1998 Zhangbei (China) earthquake (dip-slip), and a simulated event with a normal fault with right-lateral slips. All the case studies sugguest the robustness and reliability of the integrated approach.
Experimental Atherosclerosis Reductions by Hypolipidemic Drugs

Experimental Atherosclerosis Reductions by Adv Clin Res. Abstract This article summarizes the series of experiments done in New Zealand rabbits that developed aortic lesions being fed a high cholesterol diet, varying from 0,5% to 1,5% of the chow. Planimetry in statin treated rabbits showed a
Law Enforcement Referral of At-Risk Youth: The SHIELD Program

Not only are officers familiar with the youth in their communities, they are increasingly knowledgeable about risk and protective factors related to delinquency. This Bulletin describes how the SHIELD program mobilizes these assets to identify youth at risk of involvement in violent behavior, substance abuse, and gang activity and to address their needs through a multidisciplinary team approach involving representatives from the community, schools, and service agencies.
Alterations in Resting-State Functional Connectivity Link Mindfulness Meditation With Reduced Interleukin-6: A Randomized Controlled Trial

4 アブストラクト マインドフルネス瞑想訓練は,健康指標の向上のために用いられるが,根底にある生物学的メカニズムは知ら れていない. マインドフルネス瞑想が Default Mode Network(DMN)とトップダウン実行制御に重要である背 外側前頭前野(dorsolateral prefrontal cortex:dlPFC)との安静時機能的結合を増加させる可能性があることを 示した先行研究をもとに,マインドフルネス瞑想訓練が DMNと dlPFCとの結合を増やすかどうか,また,これ らの結合変化がインターロイキン 6(Interleukin-6:IL-6)の向上を説明するかどうかを検討する. 被験者はストレスを受けた仕事を探している失業中の成人 35名で,3日間住み込みでマインドフルネス瞑想か リラクゼーショントレーニングプログラムのいずれかに参加した. 被験者に対して,プログラムの前後に 5分間 の安静時状態の撮像を行った. また,プログラムの介入前および介入後 4か月の追跡調査時に血液サンプルを採 取し,全身性炎症のバイオマーカーである IL-6の分析を行った. 後部帯状皮質をシードベースとし,DMNの安静時機能的結合を検討したところ,リラクゼーショントレーニン グではなく,マインドフルネス瞑想訓練で左 dlPFCと後部帯状皮質の結合が増加した(p<.05). 訓練前から訓練 後にかけての後部帯状皮質と dlPFCの結合の変化は,4か月の追跡調査での IL-6におけるマインドフルネス瞑想 訓練の改善を統計的に示した. 具体的には,これらの安静時機能的結合の変化は,追跡調査時に IL-6に対するマ インドフルネス瞑想の効果の 30%が統計的に示された. これらのことから,マインドフルネス瞑想訓練が DMNと安静時のトップダウン実制御を担う左 dlPFCが機能 的に結合するという先行研究を証明し,炎症性疾患リスクの指標の改善も示した.
Emerging Challenges in the Diagnosis and Treatment of Autoimmune Encephalitis

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Discoidin Domain Receptors: Unique Receptor Tyrosine Kinases in Collagen-mediated

The discoidin domain receptors (DDRs) are receptor tyrosine kinases that recognize collagens as their ligands. DDRs display unique structural features and distinctive activation kinetics, which set them apart from other members of the kinase superfamily. DDRs regulate cell-collagen interactions in normal and pathological conditions and thus are emerging as major sensors of collagen matrices and potential novel therapeutic targets. New structural and biological information has shed light on the molecular mechanisms that regulate DDR signaling, turnover, and function. This minireview provides an overview of these areas of DDR research with the goal of fostering further investigation of these intriguing and unique receptors. The discoidin domain receptor (DDR) 2 family comprises two distinct members, DDR1 and DDR2, which were initially dis
Atmospheric deposition at groundwater dependent wetlands: implications for effective catchment management and Water Framework Directive groundwater classification in England and Wales

This report is the product of an Environment Agency (EA) contract co-funded by the British Geological Survey (NERC) to review and collate information regarding atmospheric and terrestrial nutrient loading at groundwater dependent terrestrial ecosystems (GWDTEs) in both England and Wales (the inclusion of Welsh sites are covered by the co-funding from BGS and not from EA funding. Many GWDTEs are low nutrient systems therefore any increase in loading can have a detrimental effect upon the ecology. In order to better protect GWDTEs in England and Wales it has become increasingly important to understand the sources of nutrients so that effective regulation and management can be applied to return the GWDTEs into favourable condition. This report highlights many knowledge gaps and also provides the first comparison of two national assessments, Critical Load (assessment of atmospheric deposition) and Threshold Value (assessment of groundwater nitrate levels). It shows that nearly 90% of the GWDTEs in England and Wales exceed their Critical Load for atmospheric deposition. Implications for future Water Framework Directive classification cycles are highlighted. Suggestions are made for suitable GWDTEs to be included in a future research project. The project will aim to provide a methodology to define source attribution from both atmospheric and terrestrial nutrients, enabling environment managers to make effective decisions to project GWDTEs.