Miracle-dz/UniFAR-FTUs huggingface dataset:
O chute com o membro dominante e não dominante realizado com a bola parada e em deslocamento no futsal

The futsal has been studied under the focus of several themes. This work analyzed the futsal in the Biomechanics perspective. The aim of this study was to describe the kick with the dominant and non-dominant limb performed with the stationary and in displacement ball in futsal. Ten players participated of the UNESP Campus Rio Claro futsal adult team. They performed ten kicks with the ball in displacement and ten kicks with the stationary ball (five kicks with each limb for each situation). The kicks performed were the maximal instep kicks and should hit a 1 x 1 m target positioned in the goal centre. The movements were recorded by six cameras with focus in the passive markers placed in the participants inferior limbs. The kicking images were transferred to the computer and worked in the DVIDEOW software. The extracted files of this software were smoothed through the LOESS function and joints rotation angles were calculated by the Euler method. For that, it was defined the ortonormal base associated to each corporal segment through i, j and k versores. The angular speed was calculated through angles derived for the time and for each joint. The kicks performance was analyzed through the observation of the success or failure of hitting in the target. For the ball and kick limb foot speed were carried through, in function of the time, a linear regression of first degree for X and Y axles and a linear regression of second degree for Z axle. Then, the average ball and foot speed was calculated from the covered distance divided for the time for the data parameterized in each kick. The results for the angular kinematic standard and angular speed showed significant differences among dominant and not dominant kick and support limb. For the kick type small differences was
Finding Drug Repurposing Candidates for Neurodegenerative Diseases using Zebrafish Behavioral Profiles

Drug repurposing can accelerate drug development while reducing the cost and risk of toxicity typically associated with de novo drug design. Several disorders lacking pharmacological solutions and exhibiting poor results in clinical trials - such as Alzheimer’s disease (AD) - could benefit from a cost-effective approach to finding new therapeutics. We previously developed a neural network model, Z-LaP Tracker, capable of quantifying behaviors in zebrafish larvae relevant to cognitive function, including activity, reactivity, swimming patterns, and optomotor response in the presence of visual and acoustic stimuli. Using this model, we performed a high-throughput screening of FDA-approved drugs to identify compounds that affect zebrafish larval behavior in a manner consistent with the distinct behavior induced by calcineurin inhibitors. Cyclosporine (CsA) and other calcineurin inhibitors have garnered interest for their potential role in the prevention of AD. We generated behavioral profiles suitable for cluster analysis, through which we identified 64 candidate therapeutics for neurodegenerative disorders.
Improved bounds for the randomized decision tree complexity of recursive majority ∗

We consider the randomized decision tree complexity of the recursive 3-majority function. For evaluating a height h formulae, we prove a lower bound for the δ-two-sided-error randomized decision tree complexity of (1 − 2δ)(5/2), improving the lower bound of (1 − 2δ)(7/3) given by Jayram et al. (STOC ’03). We also state a conjecture which would further improve the lower bound to (1− 2δ)2.54355. Second, we improve the upper bound by giving a new zero-error randomized decision tree algorithm that has complexity at most (1.007) · 2.64946, improving on the previous best known algorithm, which achieved (1.004) · 2.65622. Our lower bound follows from a better analysis of the base case of the recursion of Jayram et al. Our algorithm uses a novel “interleaving” of two recursive algorithms. ∗Partially supported by the French ANR Defis program under contract ANR-08-EMER-012 (QRAC project) and the European Commission IST STREP Project Quantum Computer Science (QSC) 25596. †LIAFA, Univ. Paris 7, CNRS; F-75205 Paris, France. magniez@liafa.jussieu. fr ‡Department of Combinatorics and Optimization, and Institute for Quantum Computing, University of Waterloo; and Perimeter Institute for Theoretical Physics. Address: 200 University Ave. W. , Waterloo, ON, N2L 3G1, Canada. Email: ashwin.nayak@uwaterloo.ca. Research supported in part by NSERC Canada. Research at Perimeter Institute for Theoretical Physics is supported in part by the Government of Canada through Industry Canada and by the Province of Ontario through MRI. Work done in part while visiting LRI—CNRS, Univ Paris-Sud, Orsay, France, and Centre for Quantum Technologies, National University of Singapore, Singapore. §LIAFA, Univ. Paris 7, CNRS; F-75205 Paris, France; and Centre for Quantum Technologies, National University of Singapore, Singapore 117543; santha@lri.fr. Research at the Centre for Quantum Technologies is funded by the Singapore Ministry of Education and the National Research Foundation. ¶LIAFA, Univ. Paris 7, CNRS; F-75205 Paris, France; and Univ. Paris-Sud, F-91405 Orsay, France. dxiao@lri.fr
A Personal Knowledge Management Tool That Supports Organizational Knowledge Management

This paper describes the concept and design of PK-MAST (a Personal Knowledge Management And Sharing Tool), which is a novel knowledge management tool and framework that seeks to bridge the gap between personal knowledge management and organizational knowledge sharing. PK-MAST gives the user a strong ‘personal’ feel in capturing knowledge for his/her own purposes and is very easy to use, but it also supports selective knowledge sharing with minimal effort from the user.
Direct Product Theorems for Classical Communication Complexity via Subdistribution Bounds

A basic question in complexity theory is whether the computational resources required for solving k independent instances of the same problem scale as k times the resources required for one instance. We investigate this question in various models of classical communication complexity. We introduce a new measure, the subdistribution bound , which is a relaxation of the wellstudied rectangle or corruption bound in communication complexity. We prove that the one-way version of this bound tightly captures the one-way public-coin randomized communication complexity of any relation, and that the two-way version bounds the two-way public-coin randomized communication complexity from below. More importantly, we show that the bound satisfies the strong direct product property under product distributions for both oneand two-way protocols, and the weak direct product property under arbitrary distributions for two-way protocols. These results subsume and strengthen, in a unified manner, several recent results on the direct product question. The simplicity and broad applicability of our technique is perhaps an indication of its potential to solve yet more challenging questions regarding the direct product problem. ∗School of Computer Science, and Institute for Quantum Computing, University of Waterloo, 200 University Ave. W. , Waterloo, ON N2L 3G1, Canada. Email: rjain@cs.uwaterloo. ca. Research supported in part by ARO/NSA USA. †Institut für Informatik, Goethe-Universität Frankfurt, 60054 Frankfurt am Main, Germany. E-mail: hklauck@gmail.com. Supported by DFG grant KL 1470/1. ‡Department of Combinatorics and Optimization, and Institute for Quantum Computing, University of Waterloo, 200 University Ave. W. , Waterloo, ON N2L 3G1, Canada. E-mail: anayak@math.uwaterloo. ca. Research supported in part by NSERC Canada, CIFAR, MITACS, CFI, OIT, and an ERA from the Province of Ontario. A.N. is also Associate Member, Perimeter Institute for Theoretical Physics, Waterloo, Canada. Research at Perimeter Institute for Theoretical Physics is supported in part by the Government of Canada through NSERC and by the Province of Ontario through MRI.
Commerce by a Frozen Sea: Native Americans and the European Fur Trade

Introduction: Native Americans and Europeans in the Eighteenth-Century Fur Trade 1. Hats and the European Fur Market 2. The Hudson's Bay Company and the Organization of the Fur Trade 3. Indians as Consumers 4. The Decline of Beaver Populations 5. Industrious Indians 6. Property Rights, Depletion, and Survival 7. Indians and the Fur Trade: A Golden Age? Epilogue. The Fur Trade and Economic Development Appendixes A. Fur Prices, Beaver Skins Traded, and the Simulated Beaver Population at Fort Albany, York Factory, and Fort Churchill, 1700-1763 189 B. Simulating the Beaver Population C. A Model of Harvesting Large Game: Joint Ownership Versus Competition D. Food and the Relative Incomes of Native Americans and English Workers Notes Bibliography Index Acknowledgments
Korean treatment recommendations for patients with axial spondyloarthritis

We aimed to develop evidence-based recommendations for treating axial spondylarthritis (axSpA) in Korea. The development committee was constructed, key clinical questions were determined, and the evidence was searched through online databases including MEDLINE, Embase, Cochrane, KoreaMed, and KMbase. Systematic literature reviews were conducted, quality of evidence was determined, and draft recommendations were formulated according to the Grading of Recommendations Assessment, Development, and Evaluations methodology. Recommendations that reached 80% consensus among a voting panel were finalized. Three principles and 21 recommendations were determined. Recommendations 1 and 2 pertain to treatment strategies, regular disease status assessment, and rheumatologist-steered multidisciplinary management. Recommendations 3 and 4 strongly recommend patient education, exercise, and smoking cessation. Recommendations 5~12 address pharmacological treatment of active disease using nonsteroidal anti-inflammatory drugs, glucocorticoids, sulfasalazine, biologics, and Janus kinase inhibitors. Recommendations 13~16 address treatment in stable disease. We suggest against spa and acupuncture as therapies (Recommendation 17). Recommendations 18 and 19 pertain to total hip arthroplasty and spinal surgery. Monitoring of comorbidities and drug toxicities are recommended (Recommendations 20 and 21). Recommendations for axSpA treatment in a Korean context were developed based on comprehensive clinical questions and evidence. These are intended to guide best practice in the treatment of axSpA.
An assessment of global and regional sea level in a suite of interannual CORE-II simulations: a synopsis

There is a growing number of observation-based measures of sea level related patterns with the advent of the Argo floats (since the early 2000s) and satellite altimeters (since 1993). These measures provide a valuable means to evaluate aspects of global model simulations, such as the global ocean-sea ice simulations run as part of the interannual Coordinated Ocean- ice Reference Experiments Griffies et al. (2009), Danabasoglu et al. (2013). In addition, these CORE-II simulations provide a means for evaluating the likely mechanisms causing sea level variations, particularly when models with different skill are compared against each other and observations. We have conducted an assessment of CORE-II simulations from 13 model configurations Griffies et al. (2013), with a focus on their ability to capture observed trends in ocean heat content as well as the corresponding dynamic sea level over the period 1993- 2007. Here, we provide a synopsis of the assessment.
DESCRIPCIÓN DEL DESARROLLO ORGANIZACIONAL Y CURRICULAR DE DIFERENTES TIPOS DE CENTRO Y ETAPAS EDUCATIVAS Description of the organizational and curricular development of different types of centres and educational stages

This contribution synthesizes the study that there are developing teachers of the Area of Didactics and school Organization of the UPV and of the UAB (2005-06). His content approaches the relations between the stadiums of organizational development and curricular and the school results. The first information suggests that there is a major cohesion and coherence in the small centres, of public ownership and of an alone linguistic model. Curiously, this apparent common identity rests more on the participative structure and on the systems of learning organizational and not so much on the institutional culture and the collaborative culture. The above mentioned depend more of the size of the centre and of the linguistic model that of the ownership. The attention calls that the leadership transformational links itself more to the public ownership and to the centres of secondary, not relating significantly to the size of the centre, the linguistic model or the years linked to the exercise of charges.
Learning-by-Exporting: What We Know and What We Would Like to Know

This article revises the thesis that exporting firms learn to be more innovative and efficient as they have contact with certain information flows from their foreign activity. It begins by exploring the connections between two concepts: self-selection and learning-by-exporting. The study proceeds with a comparative analysis of the most recent literature and presents common facts and key issues still open to debate. Learning-by-exporting should be measured directly using firms' innovative performance. Given the lack of suitable data on firms' innovative activities, most studies—although without consensus—have followed an indirect approach using productivity measures.
attitudes towards chatbots in education: a technology acceptance model approach considering the

The appearance of Artificial Intelligence implementations, such as text-based virtual assistants (chatbots) in education is relatively new. These implementations can be useful for helping teachers and students to solve both educational questions and routine tasks. This paper examines the factors that explain teachers’ acceptance of chatbots through the dimensions of the Technology of Acceptance Model (perceived usefulness and perceived ease of use), its conversational design (use of social language and proactiveness), and the teachers’ age and digital skills. The data collection process included a pretest and an online survey with four different types of chatbots. We analyze 225 responses of primary and secondary education teachers. The results show that the perceived easiness and perceived usefulness leads to greater acceptance of chatbots. As for the chatbots’ features, formal language by a chatbot leads to a higher intention of using them. These results can help in chatbot design and communication decisions, improving the acceptance of the educational community.
Evidence of a long‐term increase in tropospheric ozone from Pic du Midi data series: Consequences: Positive radiative forcing

The rate at which ozone is increasing in the troposphere is uncertain due to the lack of accurate long-term measurements. Old ozone measurements obtained at the Pic du Midi Observatory (3000 m high, southwestern France) were recently rediscovered. Four sets of data available at this station are presented herein: (1) 1874–1881 and (2) 1881–1909 by the Schonbein method and (3) 1982–1984 and (4) 1990–1993 by UV absorption analyzers. The results show an increase in ozone by a factor of 5 since the beginning of the twentieth century, corresponding to an exponential increase of 1.6% per year, although this trend is probably higher (2.4% per year) for the last few decades. A stable 10 ppb ozone mixing ratio is observed during the first 20 years of the series, which is representative of the preindustrial era ozone level. The increase is seen to start around 1895. Other data, obtained at various European high-altitude stations between 1920 and 1980, tie in closely with the Pic du Midi observations. A tentative evaluation of the impact of tropospheric ozone on radiative forcing confirms that ozone is currently the second most significant greenhouse gas, responsible for 22% and 13% of radiative forcing changes since 1800 in the northern and southern hemispheres, respectively. If these rates were to be maintained in the future, ozone would continue to evolve differently in the two hemispheres (maximum level in the northern hemisphere) and could make an even more significant contribution to the radiative forcing of the northern hemisphere.
Single-Cell Transcriptome Analysis Identifies Novel Biomarkers Involved in Major Liver Cancer Subtypes

Liver cancers including hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC) are leading cause of death worldwide. Single-cell transcriptomics studies have vast potential in advancing our understanding of cancers by defining the cellular composition of different solid tumor types. We peformed an integrated analysis using single-cell RNA sequencing (scRNA-seq) data from cancerous and healthy liver tissues in order to identify the molecular progression and intercellular heterogeneity across cell types in the liver cancer. Moreover, we performed a subtype specific analyses, separately for HCC and ICC, to identify any molecular drivers uniquely associated with these liver cancers. The scRNA-seq dataset comprising 5 healthy controls and 19 liver cancer patients were collected from Human Cell Atlas and Gene Expression Omnibus (GEO), respectively. Our analyses confirmed upregulation of four previously known malignant cell marker genes, namely, EPCAM, KRT19, KRT7 and S100P in the cancerous liver cells. Of these, KRT7 gene has been reported to be associated with ovarian cancer in the past studies. Noteworthy, four marker genes specific to the G1/S (MCM5 and PCNA) and G2/M phases (HMGB2 and CKS2) of the cell cycle were upregulated in the cancerous liver cells. This indicates that these four marker genes are actively dividing in these two phases in cancerous cells as compared to normal liver cells. Our differential expression analysis identified 2 upregulated genes (ATF3 and S100A11) and 2 downregulated genes (FCN3 and FGB) in the liver cancer. Our subtype based differential expression analysis identified 4 genes (HSPA6, LMNA, ATP1B1 and DCXR) specific to HCC and 3 genes (HSPB1, APOC3 and APOA1) specific to ICC. CD4+ T-cell, Hepatocyte, neutrophil, mesenchymal cells and liver bud hepatic cells are the predominant cell-types in liver cells. Our scRNA-seq study revealed the mesenchymal cells as potential malignant cell types in liver cancers. Our work suggests future research on developing liver cancer subtypes therapies could target these cell types and associated molecular markers.
Transformational Leadership and Police Culture: Outlining the Contours of a Troubled Relationship

For a number of years there has been a sustained acknowledgement of the worth of ‘transformational’ leadership as a catalyst for change within police organisations. Academics, policy makers and senior officers alike have pronounced the benefits to be enjoyed from the implementation of such leadership models, not least in respect of promoting cultural change. However, this paper will present a counter argument to suggest that the application of transformational leadership models to policing contexts is, if not flawed, then at least worthy of more robust critique that that which, to date, it has been subjected to. In doing so, this paper explores the concept of ‘transformational’ leadership and its relevance to policing contexts. Additionally, the paper will suggest that claims of success in effecting cultural change within police organisations are likely to rest on simplistic conceptions of police culture and its relationship to police behaviour.
ScholarWorks @ UVM ScholarWorks @ UVM The effects of climate change on density-dependent population The effects of climate change on density-dependent population dynamics of aquatic invertebrates dynamics of aquatic invertebrates

Global climate change has the potential to alter aquatic communities through changes in evapotranspiration and increased variability in precipitation. We used aquatic mesocosms to test the impacts of variable precipitation on population dynamics of common mosquito (Culicidae) and midge (Chironomidae) larvae that inhabit vernal pools. In a mixed deciduous forest in northern Vermont, USA, we orthogonally crossed seven levels of mean water level (increased rainfall) with seven levels of water level coeﬃ cient of variation (more variable rainfall) to simulate a broad array of climate change scenarios in 49 experimental mesocosms. Th e average abundance of Culicidae was highest at low water levels, whereas the average abundance of Chironomidae was highest at higher water levels and low variability in water level. Treatments and environmental and spatial covariates collectively explained 49% of the variance in mean abundance. For both taxa, we ﬁ t hierarchical Bayesian models to each 16-week time series to estimate the parameters in a Gompertz logistic equation of population growth with density dependence. We found that Culicidae population growth rate increased with decreasing water levels and that 87% of the vari- ance in Chironomidae density dependence could be explained by treatment. Collectively, these results suggest that climate change can alter abundances aquatic invertebrate taxa but not necessarily through the same mechanism on all populations. In the case of Culicidae the abundance is aﬀ ected by changes in growth rate, and in Chironomidae by changes in the strength of density dependence.