Miracle-dz/UniFAR-FTUs huggingface dataset:
A Study on the Pharmaceutical & Chemical Characteristics and Analysis of Natural Curcumin Extract

Natural Curcumin belongs to Zingiber Officinale Roscoe was known to possess natural odor, natural taste, natural color, and other pharmaceutical & chemical characteristics. Natural Curcumin extract was made to use ethanol as a solvent was to show a yellow color having state of solid powder and an active component. Natural Curcumin extract tested pharmaceutical & chemical experiment to dilute in curcumin 1%-water solution. Curcumin extract tested antimicrobial experiment using microbe, and tested dye experiment using fiber. Some conclusions in the result of characteristics experiment was obtained as follow. The result of antimicrobial experiment showed that the growth of staphylococcus aureus (ATCC-001) and aspergillus niger (ATCC-002) as microbes decreased according to passage of time. This phenomenon could know that Curcumin compoment showed influence to antimicrobial effect. Also, the result of dye experiment showed that cotton and sick with fiber dyeing dyed in direction of dark yellow color. This phenomenon could know that Curcumin extract showed influence to dyeing effect in observation of optical electron microscope(OEM.) The result of instrument analysis ascertained inorganic components of K(53.300ppm), Na(1.150ppm), Ca(0.711ppm), Ti(0.351ppm), Li(0.256ppm), Cu(0.233ppm) etcs from Curcumin component with ICP/OES, and ascertained organic components of propanoic acid(1.859), benzene(10.814), phenol(14.194) etcs from Curcumin component with GC/MSD.
Evaluation of Vitamin D in Preterm Neonates and Effects of its Supplementation in Preterm Neonates with Respiratory Distress Syndrome

Background: Prematurity and related problems, especially respiratory distress syndrome, are one of the main challenges for neonatal medicine. Many studies have shown the relationship between lung development and vitamin D. Objective: To investigate Vitamin D status and to evaluate the effect of vitamin D supplement as adjuvant therapy in the management of respiratory distress syndrome (RDS) in preterm infants. Patients and Methods: This study included 90 preterm neonates chosen from those at NICU of Minya General Hospital and Al-Azhar University, Assiut, Egypt. The cases were divided into two main groups; a group with RDS (case group 66 cases) and a group without RDS (control group =24 cases). The group with RDS was further subdivided into three subgroups (subgroup I received just traditional therapy and the subgroup II received traditional therapy plus vitamin D 400 IU/day, while subgroup III received traditional therapy plus vitamin D 800 IU/day). Results: The RDS group had lower neonatal and maternal vitamin D concentrations than the group without RDS. We found a strong positive correlation between neonatal and maternal vitamin D levels on the day of delivery. The subgroups supplemented with vitamin D had a significant improvement in all ABG parameters, lower Downs score, less hospital stay, less morbidity than the subgroup without vitamin D supplementation. Conclusion: Administration of vitamin D as adjuvant therapy in cases of RDS was associated with a significant decrease in severity, rate of complications, and duration of hospital stay in the subgroup received 800 IU/Day compared to the subgroup received 400 IU/Day.
Development of a High-Energy Red Clover

Red clover (Trifolium pratense L.) is one of the most important forage legumes in grassland agroecosystems worldwide. Although red clover has a high biomass potential and is particularly valued for its high protein content, its herbage lacks the high-energy carbohydrates required to meet the productivity potential of modern livestock breeds. Like most plants, red clover accumulates diurnal starch in its leaves during the day as a temporary carbon store of photosynthesis, but harvesting this starch is challenging. To develop a harvestable high-starch agronomic trait in red clover, a reverse genetic pipeline was established to identify beneficial alleles in the gene encoding the starch degradation enzyme GWD1 which naturally accumulate starch. Within the targeted region, we were able to identify several rare and common variants. Of these variants, one that was present at a rate of approximately 25% in the original population contributed to a starch increase of 20% in selected populations enriched for this allele. Implementation of such a highstarch trait in forage production is envisioned to maximize the energy content and protein absorption of forage crops in order to deliver a higher proportion of the feed intake from environmentally sustainable and locally produced roughage.
Contamination potential of biofilms in water distribution systems

Biofilms are ubiquitous in drinking water systems, either in the form of thin and patchy colonies or as surface-covering multiple layers. In biofilters they are used for the elimination of biologically degradable substances. However, they occur in other sites, e.g., on the walls of containers and pipes, on sediment and on suspended particles. They can rise problems by contamination of the water phase by detaching biofilm organisms. Biofilms provide a possible habitat for hygienically relevant microbes in which they can persist and even multiply. Here they are protected against disinfectants, in particular if located in corrosion products, sediments or ingested by protozoa which feed on biofilm cells. Biofilms are related to the occurrence of “black water” and malodours. They are involved in the corrosion of metals, mineral materials and synthetic polymers. The limiting factor for biofilm growth is usually the availability of nutrients, mainly provided either by biodegradable substances leaching from materials or from by the water phase. The extent of biofilm growth and of the occurrence of hygienically relevant organisms is still unknown and to be investigated. However, latest research indicates that such organisms do not multiply in large numbers in drinking water biofilms; it is possible that drinking water biofilms can inhibit the propagation of invading pathogens.
The Structure of the Actin-Smooth Muscle Myosin Motor Domain Complex in the Rigor State

Abstract Myosin-based motility utilizes catalysis of ATP to drive the relative sliding of F-actin and myosin. The earliest detailed model based on cryo-electron microscopy (cryoEM) and X-ray crystallography postulated that higher actin affinity and lever arm movement were coupled to closure of a feature of the myosin head dubbed the actin-binding cleft. Several studies since then using crystallography of myosin-V and cryoEM structures of F-actin bound myosin-I, –II and –V have provided details of this model. The smooth muscle myosin II interaction with F-actin may differ from those for striated and non-muscle myosin II due in part to different lengths of important surface loops. Here we report a ∼6 A resolution reconstruction of F-actin decorated with the nucleotide-free recombinant smooth muscle myosin-II motor domain (MD) from images recorded using a direct electron detector. Resolution is highest for F-actin and the actin-myosin interface (3.5–4 A) and lowest (∼6–7 A) for those parts of the MD at the highest radius. Atomic models built into the F-actin density are quite comparable to those previously reported for rabbit muscle actin and show density from the bound ADP. The atomic model of the MD, is quite similar to a recently published structure of vertebrate non-muscle myosin II bound to F-actin and a crystal structure of nucleotide free myosin-V. Larger differences are observed when compared to the cryoEM structure of F-actin decorated with rabbit skeletal muscle myosin subfragment 1. The differences suggest less closure of the 50 kDa domain in the actin bound skeletal muscle myosin structure.
Comparison of organic and conventional farming for onion yield, biochemical quality, soil organic carbon, and microbial population

ABSTRACT In an ongoing field experiment, organic and conventional farming (control) were compared for onion bulb yield, biochemical quality, soil organic carbon (SOC), and microbial activity after the sixth cropping cycle. The treatments used for organic production were farmyard manure (FYM, 20,000 kg ha−1), poultry manure (PM, 10,000 kg ha−1), vermicompost (VC, 10,000 kg ha−1), neem cake (NC, 5000 kg ha−1), and a combination of FYM (5000 kg ha−1), PM (2500 kg ha−1), VC (2500 kg ha−1), and NC (1250 kg ha−1); all treatments were compared with the control. Organic treatments produced 24.6–43.6% lower yield consistently for 6 years than the control treatment. No significant difference was observed between PM, FYM, and VC treatments for the bulb yield. Bulb analysis during the sixth year indicated that plants that received FYM, PM, or VC had higher levels of total phenol, total flavonoid, ascorbic acid, and quercetin-3-glucoside than the control plants. All the five organically treated sets had significantly higher values of SOC, microbial population, fungal-to-bacterial ratio, and dehydrogenase activity than the control and the initial values in each treated set. The results indicate that FYM, PM, or VC application enhances biochemical quality and organic farming is more sustainable than conventional farming.
Structural Equation Model on Work Engagement among Employees of Large Retail Enterprises in Region Xii

The ultimate goal of this research undertaking was to identify the best fit model involving the following exogenous variables: transformational leadership, motivation, and human resource management practices to endogenous variable – work engagement. A survey questionnaire was issued to the various large retail employees in Region XII, Philippines with 425 respondents for the purpose of data collection. The research method used in the analysis was descriptive — correlation design was used to find the best fit model through structural equation modeling. The results revealed that the model presented positive relationship between transformational leadership, motivation and human resource management practices and work engagement. Nevertheless, the three established exogenous variables of transformational leadership, motivation, and human resource management practices emerged as the primary predictors of work engagement, taking into account their observed variables as depicted in the study's final and best fit model.
Dépôts chimiques à partir d’une phase gazeuse

Parmi les revetements susceptibles de conferer des proprietes nouvelles aux surfaces qu’ils recouvrent, ceux obtenus par le procede de depots chimiques a partir d’une phase gazeuse (Chemical Vapor Deposition : CVD) connaissent incontestablement un grand developpement. Ce procede consiste a mettre un compose volatil du materiau a deposer en contact soit avec un autre gaz au voisinage de la surface a recouvrir, soit avec la surface en question, de facon a provoquer une reaction chimique donnant au moins un produit solide. La temperature du substrat fournit l’energie d’activation necessaire pour declencher la reaction chimique et favoriser, lorsqu’elle est suffisamment elevee (800 a 1 000 o C), la diffusion dans ce substrat des atomes apportes a la surface. Cette diffusion a l’etat solide entraine une modification des produits de la reaction et assure generalement une bonne adherence au revetement. Ce procede permet d’obtenir des couches d’epaisseur variable de pratiquement tous les metaux, alliages ou composes metalliques, sur des materiaux conducteurs ou isolants. Il permet aussi d’obtenir, en plus des revetements, des poudres fines ou des echantillons massifs. L’appareillage pour l’obtention de ces depots varie considerablement suivant le type de depots que l’on desire (procedes isothermes, non isothermes, statiques, dynamiques, basse pression, etc.). Les proprietes des revetements (adherence, porosite, stœchiometrie, purete, etc.) sont generalement bonnes. Les principaux domaines d’application du procede CVD peuvent se classer en deux categories suivant que le produit forme donne un revetement (ou couche) sur un substrat, ou un produit solide independamment d’un substrat. L’obtention d’un revetement permet la protection contre l’usure mecanique (T iC, T iN, Al 2 O 3 , etc.), la protection contre la corrosion et l’oxydation a haute temperature (Cr, Al, Si, etc.), la realisation de composants pour la microelectronique (GaAs, Si, AlN, etc.). La formation de produits solides conduit a des produits pulverulents de grande purete, a des monocristaux et permet de consolider des materiaux poreux ou frittes. Les techniques CVD completent et remplacent avantageusement d’autres modes de depots (evaporation sous vide, projection cathodique, electrodeposition, etc.). C’est pour cela qu’elles sont devenues preponderantes dans des domaines industriels tels que l’aeronautique, l’electronique, la chimie, etc.
La robótica y el diseño de APP: una posibilidad para potenciar el pensamiento matemático de los estudiantes de pregrado

In the national educational context and for students at the basic and secondary education levels, their appropriations of mathematical concepts tend to be low and this becomes especially evident when they enter higher education. It is necessary to implement active and innovative methodologies that promote in the student new dynamics for the development of a mathematical Knowledge; To answer to this problem, from the research group Entre Ciencia e Ingenieria of the Faculty of Basic Sciences and Engineering of the Catolica de Pereira University, it is proposed to carry out a methodological proposal based on the use of robotic devices LEGO MINDSTORMS and mobile platforms such as App Inventor with the purpose that the student improves their levels of competence in numerical, variational and geometric thoughts.
MANAGEMENT OF BLEEDING AFTER ENDOSCOPIC BILIARY SPHINCTEROTOMY IN PATIENTS WITH OR WITHOUT COAGULOPATHY DEFECTS

Background: Post Endoscopic sphincterotomy (ES) bleeding is a common complication, and it can be challenging to manage post ES bleeding through a side-viewing endoscope. Objective: To establish a well-accepted clinical strategy for management of bleeding after endoscopic biliary sphincterotomy in patients with or without coagulopathy defects. Patients and Methods: This prospective interventional selective study was carried out on 100 consecutive patients with jaundice at General Surgery Department, Al- Azhar University Hospitals (Cairo) Egypt. All patients underwent ERCP during the period between January 2016 and August 2019. Patients were divided into 2 equal groups according to presence or absence of coagulopathy: Group A without coagulopathy defect, and group B with coagulopathy defect. Results: Among 100 patients with endoscopic retrograde cholangiopancreatography (ERCP), post ES bleeding was recorded in 33 patients. Only 1 of 33 was among group A which represented 3% of bleeding cases, and 1% of the total. The cause was vigorous sphincterotomy. Of 33 patients, 32 were among group B, and represented 97% of bleeding cases, and 32% of total cases in our study. The arrangement of the use of different hemostatic measures in our study was based on accessibility of the facilities and also severity of bleeding. In mild cases, bleeding stopped simply with balloon tamponade. If not, adrenaline spray was used. Endoclip was used for difficult and recurrent cases. Delayed bleeding occurred (1±7 days -mean, 2.5 days) following the procedures. Among the 9 patients with delayed bleeding, 7 patients were managed by endoscopic intervention. The other 2 patients managed conservatively by drugs and intravenous fluids with. No patient required angiography or surgery for delayed bleeding. Conclusion: Patients must be carefully assessed and prepared pre procedure. Centers must be equipped with all hemostatic measures and facilities. Endoscopists must be well trained and qualified. Bleeding was controlled in all patients easily without morality.
Application of time-of-flight aerosol mass spectrometry for the real-time measurement of particle-phase organic peroxides: an online redox derivatization–aerosol mass spectrometer (ORD-AMS)

Abstract. Aerosol mass spectrometers (AMS) are frequently applied in atmospheric aerosol research in connection with climate, environmental or health-related projects. This is also true for the measurement of the organic fraction of particulate matter, still the least understood group of components contributing to atmospheric aerosols. While quantification of the organic and/or inorganic aerosol fractions is feasible, more detailed information about individual organic compounds or compound classes can usually not be provided by AMS measurements. In this study, we present a new method to detect organic peroxides in the particle phase in real-time using an AMS. Peroxides (ROOR') are of high interest to the atmospheric aerosol community due to their potentially high mass contribution to SOA, their important role in new particle formation and their function as “reactive oxygen species” in aerosol–health-related topics. To do so, supersaturated gaseous triphenylphosphine (TPP) was continuously mixed with the aerosol flow of interest in a condensation/reaction volume in front of the AMS inlet. The formed triphenylphosphine oxide (TPPO) from the peroxide–TPP reaction was then detected by an aerosol mass spectrometer (AMS), enabling the semiquantitative determination of peroxide with a time resolution of 2 min. The method was tested with freshly formed and aged biogenic VOC and ozone SOA as well as in a short proof-of-principle study with ambient aerosol.
Sociodemographic profile, clinical characteristics, anxiety, and depression of 74 patients infected with COVID-19: first report from Bangladesh

Background: The pandemic of Corona Virus Disease 2019 (COVID-19) has cost a large number of lives and is causing substantial mental stress among people. We conducted a study to identify the sociodemographic and clinical characteristics and prevalence of anxiety and depression among confirmed COVID-19 cases in Bangladesh.Methods: An online cross-sectional survey using a preformed questionnaire adapted in Google form was conducted for data collection. The form was shared along with a brief introduction and rationale via Facebook, Twitter, Facebook Messenger, Viber, and What’s App. Formal ethical clearance was taken from the Biomedical Research Foundation, Bangladesh. Informed consent was ensured before participation.Results: Seventy-four patients with COVID-19 who had an average age of 42.59±14.43 years with male predominance (77%) were included. A total of 29.7% were doing health-care related jobs, and 14.9% lost their jobs due to COVID-19. Patients had a median income of BDT 30000. Of all, 87.8% of patients were symptomatic and presented with fever (77%), cough (58.8%), breathlessness (24.3%), myalgia (24.3%), sore throat (21.6%), fatigue (17.6%), nausea and/or vomiting (12.2%), headache (12.2%), runny nose (9.5%), chest pain (9.5%), diarrhea (8.1%), ARDS (2.7%), stuffy nose (2.7%), conjunctivitis (1.4%) and oral ulcer (1.4%). Overall, the prevalence of anxiety and depression was 60% and 52.9%, respectively. Among the participants, 11.4% had only anxiety, 4.3% had only depression and 48.6% had both.Conclusion: Patients were mostly middle aged, male and healthy workers. Typical presentations were fever and cough. Nearly two-thirds of the patients had either or both anxiety and depression.
The NO‐cGMP pathway in the rat locus coeruleus: electrophysiological, immunohistochemical and in situ hybridization studies

The effect of two nitric oxide (NO) donors, SIN‐1 and DEA/NO, as well as of the inactive SIN‐1 derivative molsidomin, was studied on locus coeruleus (LC) neurons in a slice preparation using intracellular recordings. In addition, the effect of the guanylate cyclase inhibitor ODQ was analysed. Furthermore, the effect of NO donors on cyclic guanosine monophosphate (GMP) levels in the LC was studied using the indirect immunofluorescence technique, and the expression of soluble guanylyl cyclase with in situ hybridization. In 36 of 66 LC neurons extracellular application of SIN‐1 and DEA/NO caused a hyperpolarization and a decrease in apparent input resistance. In almost 20% of neurons SIN‐1 increased the firing rate. No effect could be recorded with the brain‐inactive SIN‐1 derivative molsidomin. The membrane permeable cGMP analogue 8‐bromo‐cGMP imitated the action of SIN‐1. The hyperpolarizing effect of SIN‐1 and DEA/NO was attenuated by preincubation with the guanylyl cyclase inhibitor ODQ. The immunohistochemical analysis revealed lack of cGMP immunostaining in non‐stimulated slices, whereas SIN‐1 dramatically increased this staining in about 40% of the LC neurons, and these neurons were all tyrosine hydroxylase positive, that is noradrenergic. A large proportion of the LC neurons expressed soluble guanylyl cyclase mRNA. The present and previous results suggest that NO, released from a small number of non‐noradrenergic neurons in the LC, mainly has an inhibitory influence on many noradrenergic neurons, by upregulating cGMP levels via stimulation of soluble guanylyl cyclase. As nitric oxide synthase is present only in a small number of non‐noradrenergic neurons ( Xu et al. 1994 ), a few neurons may influence a large population of noradrenergic LC neurons, which in turn may control activity in many regions of the central nervous system.
Efficacy of N2O2 donor schiff bases and their Zn2+ complexes on various morphological and biochemical parameters of Cicer arietinum L.

ABSTRACT Schiff-base polydentate ligands types of salen and salophen can form stable complexes with Zn2+ and these metal complexes can act as a source of zinc (Zn) to plant's body if they are used as micronutrient supplements. Inspired by these facts, four different Schiff-base ligands and their Zn2+ complexes were first synthesized and then characterized by different analytical and spectroscopic techniques. To investigate their effects local chickpea seeds were treated with each ligands and complexes and different morphological and biochemical parameters were monitored. Among all the complexes and ligands it was found that the C4 complex, that is, [N,N'-(o-phenylene)bis-(3-methoxysalicylidenediamine)] monohydrate showed the maximum efficacy when treated as a micronutrient supplement for Cicer arietinum L. So that these complexes especially the C4 can act as an potential source of Zn.
Green synthesis of a vanadium(V) Schiff base complex by grinding method: study on its catalytic and anti-bacterial activity

Abstract A facile protocol was developed for the green synthesis of a Schiff base and its vanadium(V) complex. The compounds were derived from salicylaldehyde, diethylenetriamine and vanadyl sulfate by applying grinding method to overcome environmental issues with solvents. The reactions took place rapidly and products were isolated pure. The compounds were characterized with elemental, EDX, mass spectrometry, magnetic susceptibility, molar conductance, UV-vis, FTIR and NMR analysis. The synthesized vanadium(V) complex was an efficient and selective catalyst towards oxidation of organic sulfides and alcohols. The oxidation reactions were conducted under microwave irradiation as well as conventional heating. A reaction mechanism has been proposed for the catalytic oxidation reactions. The mechanism was further established by using GAUSSIAN16 suite. The complex also showed good anti-bacterial activity against Gram-positive and Gram-negative bacteria. Graphical Abstract