Miracle-dz/UniFAR-FTUs huggingface dataset:
Effects of an eight-week exercise program on parameters of the lipid profile of female students

Background Increased lipid levels are one of the major risk factors for the development of cardiovascular diseases. The aim of the current study was to evaluate the effect of short-term (8 weeks) aerobic exercise of moderate to vigorous intensity on lipid profile in young healthy females. Methods 27 female students (mean age 20.5 ± 1 year) completed 8 weeks of aerobic training that included two exercise sessions of continuous aerobic activity of moderate intensity (running 35-60 min) and one exercise session with interval training of vigorous intensity. Intervention aerobic capacity and lipid profile were examined before and after the exercise. Results Exercise intervention has caused a decrease of low density lipoprotein levels per 9.8% (from 2.52 ± 0.47 to 2.27 ± 0.53 mmol/L; p < 0.001) and significant improvement of high density lipoprotein (HDL) levels per 22.7% (from 1.29 ± 0.24 to 1.59 ± 0.24 mmol/L; p < 0.001), total cholesterol/HDL ratio per 17.2 % and aerobic capacity (VO2max) per 3.8 % (43.9 ± 3.7 to 45.56 ± 3.63 mLO2/kg/min). Conclusions The results support the hypothesis that a short-term aerobic exercise intervention of moderate to vigorous intensity may have significant effects on blood lipid profile in young healthy females.
Becoming a father: a qualitative study on the journey to fatherhood

The transition to fatherhood represents one of the most significant changes in a man’s life and brings many challenges. Despite the great importance of this period, empirical data on it are not abundant, with only a small amount of psychologi-cal research on fatherhood available in the Czech Republic; this topic is also rather marginalized abroad. This qualitative study aims to explore men’s unique experiences with the process of becoming a father and to understand how paternal iden-tity is shaped.Four men who had recently become fathers participated in the research. A semi-structured interview was conducted with each of them.Using the interpretative phenomenological analysis (IPA) approach, an in-depth analysis of the data identified five signifi-cant categories that emerge during the transition to fatherhood: responsibility and commitment to the child, father identity formation, fatherhood and motherhood, changes in the partner relationship and coping with the father role.The research suggests that the process of becoming a father is a long-term dynamic process, in which father identity is shaped and consolidated through a variety of situations and experiences. Within this process, paternal identity is also shaped through repeated comparisons and definitions of the role of the mother. Process of becoming a father involves de-velopmental, identity, personality, partnership and family aspects.
A Review of Tourism Destination Image Research

Because of the flourishing development in tourism and the intensive competition among tourism destinations,tourism destination image has been noticed by tourism researchers and marketing managers.Based on the analysis of large amount of literatures,an overall review is made on definitions,the constituent elements,influencing factors and formation process of tourism destination image.It is concluded that the constituent elements of tourism destination image include perceptual/cognitive evaluation,affective appraisal and overall image.The influencing factors of tourism destination image include personal factors and stimulus factors.The relation of the constituent elements and the influencing factors is analyzed.The formation processes of tourism destination image include static process and dynamic process.In the end,some aspects that need further study are indicated,the tendency of tourism image research is predicted,and the inspirations of these studies to tourism image studies in China are pointed out.
Professional Ethics on the Quality of Financial Reporting

This study aims to determine the extent of the impact of professional ethics on the quality of financial reporting, and how to apply it. This research is a literature review from various research sources. The results show that professional ethics has a significant relationship with the quality of financial reporting and is fundamental to the quality of an organization's financial statements. The application of quality financial reporting characters, high ethical commitment, and consistency play an important role in making quality financial reporting.
Supply Chain Management Practices and Supply Chain Integration on Organizational Performance: The Mediation Role of Competitive Capabilities

Purpose- This study's goal is to ascertain how competitive capabilites through supply chain management and supply chain integration affect organizational performance. Design/Methodology/Approach- Structural Equation Modeling, assisted by the Smart PLS program, is the data processing technique utilized in this study to examine the impact of the indicators of each of the aforementioned variables on Batik Micro, Small and Medium Enterprises in the Special Region of Yogyakarta. By distributing questionnaires, the researchers were able to collect data from up to 65 respondents. Findings- The findings of this study demonstrate that supply chain management and supply chain integration have a favorable impact on organizational performance, and that competitive skills can mediate that effect. Research limitations/implications- The study's findings are anticipated to serve as a guide and source of knowledge for business players, particularly Batik Micro, Small, and Medium Enterprises in Special Region of Yogyakarta, who are expected to understand that in order to enhance the performance of their enterprise, attention must be paid to elements that may have an impact. This study demonstrates that competitive competencies, supply chain integration, and supply chain management techniques are all elements that can impact a company's performance. Originality/value- There are still very few studies on supply chains and organizational performance in micro, small, and medium-sized businesses, particularly Batik. In this study, characteristics that are thought to have an impact on the number of Batik Micro, Small, and Medium Enterprises in a Special Region of Yogyakarta are revealed.
Nutrition and Disorders of Gut–Brain Interaction

Background: Disorders of gut–brain interaction (DGBIs) have a complex pathophysiology that is often characterized by a relationship between food ingestion and triggering of symptoms. Understanding of the underlying mechanisms and the role of nutrients as a therapeutic target are rapidly evolving. Aims and methods: We performed a narrative review of the literature using the following keywords, their acronyms, and their associations: nutrients, disorders of gut–brain interaction; functional dyspepsia; malabsorption; irritable bowel syndrome; diarrhea; constipation. Results: Functional dyspepsia displayed a significant correlation between volume, fat and/or wheat abundance, chemical composition of ingested food and symptoms of early satiety, fullness and weight loss. Carbohydrate malabsorption is related to enzyme deficiency throughout the GI tract. Food composition and richness in soluble vs. non-soluble fibers is related to constipation and diarrhea. The elimination of fermentable oligo-, di-, monosaccharides and polyols (FODMAPs) has a significant and non-unidirectional impact on irritable bowel syndrome (IBS) symptoms. Conclusions: Food volume, nutritive and chemical composition, and its malabsorption are associated with symptom generation in DGBIs. Further multicenter, randomized-controlled clinical trials are needed to clarify the underlying pathophysiology.
Mixed Reality Teleoperation Assistance for Direct Control of Humanoids

Teleoperation plays a crucial role in enabling robot operations in challenging environments, yet existing limitations in effectiveness and accuracy necessitate the development of innovative strategies for improving teleoperated tasks. This letter introduces a novel approach that utilizes mixed reality and assistive autonomy to enhance the efficiency and precision of humanoid robot teleoperation. By leveraging Probabilistic Movement Primitives, object detection, and Affordance Templates, the assistance combines user motion with autonomous capabilities, achieving task efficiency while maintaining human-like robot motion. Experiments and feasibility studies on the Nadia robot confirm the effectiveness of the proposed framework.
Combined pre-treatment and middle-treatment Epstein–Barr virus DNA load contributes to prognostication and treatment modification in nasopharyngeal carcinoma patients

Objective: To investigate whether pre-treatment and middle-treatment plasma Epstein–Barr virus (EBV) DNA loads are useful predictors of prognosis and indicators of therapy modification in nasopharyngeal carcinoma (NPC) patients undergoing radical concurrent chemoradiotherapy (CCRT). Methods: Plasma EBV DNA load was measured by quantitative polymerase chain reaction before treatment (pre-DNA) and during the second cycle of DDP (mid-DNA). The primary endpoint was 5-year progression-free survival (PFS). Results: A total of 775 NPC patients treated with CCRT were included. In total, 553 patients with pre-DNA <4000 copies/mL and 222 with ⩾4000 copies/mL. A total of 559 patients had mid-DNA undetectable and 216 had detectable. Multivariate analysis showed that pre- and mid-DNA were independent prognostic predictors of PFS [hazard ratio (HR), 2.035; 95% confidence interval (CI), 1.406–2.944; p < 0.001; HR, 1.597; 95% CI, 1.101–2.316; p = 0.014]. The area under the curve of the combination of pre-DNA and mid-DNA for 5-year PFS was higher than that of pre-DNA, mid-DNA, and tumor node metastasis (TNM) stage (0.679 versus 0.622, 0.608, 0.601). In the low-risk group (pre-DNA <4000 copies/mL and undetectable mid-DNA), patients receiving ⩽200 mg/m2 showed similar efficacy as those receiving >200 mg/m2 cumulative cisplatin dose (CCD) but were associated with fewer all-grade late toxicities. However, in the high-risk group (pre-DNA ⩾4000 copies/mL or detectable mid-DNA), patients receiving >200 mg/m2 CCD showed a higher 5-year PFS (73.1% versus 58.6%, p = 0.027) and locoregional relapse-free survival (88.5% versus 76.1%, p = 0.028) than those receiving ⩽200 mg/m2 CCD. Conclusion: The combination of pre-DNA and mid-DNA could be particularly useful for guiding risk stratification and early treatment modification for NPC treated with CCRT. A total of 200 mg/m2 cisplatin seemed to be the optimal dose for the low-risk patients, while >200 mg/m2 cisplatin may be adequate to achieve satisfactory survival outcomes in the high-risk group.
Scintillation on global navigation satellite signals and its mitigation

The scintillation effects on the Global Positioning system (GPS) or other GNSS (global navigation satellite system) receivers have been investigated by many researchers and several mitigation strategies have been proposed in this regard but the problem is not yet fully solved. This thesis covers the investigation of scintillation effects on GPS receivers and developing a mitigation approach which can play an important role in mitigating the effects of scintillation on these and other GNSS receivers. Firstly, a new GPS signal acquisition method known as the repetitive block acquisition (RBA) is presented which can be used to speed up the GPS signal acquisition in case fast acquisition is required. This acquisition method is implemented using coarse-acquisition (C/A) codes and tested by collecting real GPS data. The RBA method can also be used for other codes as well. It is rather difficult to show that how scintillation affects the acquisition process in a GPS receiver because mostly it results in tracking loop loss of lock due to cycle slip. However, during strong amplitude scintillation which is usually most important at low or near-equatorial latitudes, deep power fades resulting from amplitude scintillation result in the selection of long data records which leads to slow acquisition due to long acquisition times. It is shown in this thesis that, by using the RBA method, the acquisition time can be reduced to a fairly low level by reducing the number of computations involved in acquisition compared to other well-known methods such as the parallel FFT-based method and zero padding method (ZP). Secondly, the scintillation effects on the GPS tracking loop have also been investigated in this thesis and, based on this investigation, a new improved analogous phase scintillation index, σw φa, has been designed to more accurately represent the phase scintillation intensity at European high latitudes. This is then also validated using the real GPS data from Trondheim, Norway (63.41o N, 10.4o E). The σw φa uses dual frequency (L1 & L2) based
Recreational Use of Public Waterways and the Impact of Water Quality

This study combines routinely collected water quality data from Ireland and an on-site survey of waterway users to evaluate how water quality affects trip days demanded for recreational activities. Water quality measures employed in the analysis include Water Framework Directive (WFD) ecological status as well as several physio-chemical measures. The analysis finds some evidence that higher levels of recreational demand occur at sites with the highest quality metric measures. However, in many of the estimated models there is no statistical association between the water quality metric (e.g. WFD status, BOD, ammonia, etc.) and the duration of the recreational trip. As most sites considered in the analysis have relatively high levels of water quality this result possibly suggests that above an unspecified threshold level that water quality is not a significant determinant of recreational trip duration. Model estimates also reveal a relatively high valuation among participants for water-based recreational activity with an estimate of mean willingness to pay equivalent to €204/day
Antimicrobial and wound healing potential of naphthoquinones encapsulated in nanochitosan

Introduction: The use of chitosan in pharmaceutical formulations is an advantageous approach due to this compound intrinsic biodegradability and biocompatibility, as well as ready availability and low polymer cost. Methods: Herein, the naphthoquinones 3- chloromethylene-menadione (NQ1) and 2,3-dichloro-1,4-naphthoquinone (NQ2) were nanoencapsulated into chitosan (CNP) by the ionotropic gelatinization technique and characterized by DLS, FTIR, SEM, TGA and DSC, and their release profiles evaluated. The antimicrobial and wound healing activities were investigated. Results and Discussion: Homogeneous chitosan nanocapsulses of about 193 nm and Z potential ranging from +30.6 to +33.1 mV loaded with NQ1 (CNP-NQ1) or NQ2 (CNPQNQ2). With nanoencapsulation efficiencies of ≥ 96%, the solubility of naphthoquinones in aqueous environments was improved, making them suitable for biological system applications. The encapsulated naphthoquinones displayed a controlled release of approximately 80% for CNP-NQ1 and 90% for CNP-NQ2 over an 8 h period at 36°C. Both CNP-NQ1 and CNP-NQ2 retained the already established free naphthoquinone antimicrobial activity against two Staphylococcus aureus strains, Staphylococcus epidermidis, Streptococcus pyogenes and Pseudomonas aeruginosa. Although presenting low toxicity to healthy human cells, only CNP-NQ1 displayed therapeutic indices above 100 for S. aureus and S. epidermidis and above 27 for S. pyogenes and P. aeruginosa, allowing for safe use in human tissues. Furthermore, CNP-NQ1 did not impair the migration of human fibroblast cells in scratch assays, adding promising wound healing properties to this formulation. These findings emphasize that CNP-NQ1 may be useful in protecting injured skin tissue from bacterial contamination, avoiding skin infections not only by reducing bacterial loads but also by accelerating the healing process until complete dermal tissue recovery.
Evaluating the anti-neuropathic effects of naringin-loaded chitosan nanocarriers in a murine model of constriction injury

Peripheral neuropathies are associated with various detrimental complications, leading to life-debilitating disorders, including neuropathic pain. Hence, the current study aimed to incorporate naringin, a potential natural component, into chitosan nanoparticles (NPs) to ameliorate the complications resulting from chronic constriction injury (CCI) induced painful neuropathy. The prepared NPs had a particle size of 220 nm and PDI = 0.37, with relatively spherical morphology and zeta potential of +41.5 mV. The relevant analyses indicated the loading and high encapsulation efficiency of naringin into the NPs as well as a prolonged release of naringin. The anti-neuropathic evaluations of chronic constriction injury (CCI)-induced rats treated with naringin-loaded NPs (10 mg/kg) remarkably ameliorated hyperalgesia and cold allodynia. In addition, the treatment with naringin-loaded NPs led to improvements in sensory and locomotor impairment, as evidenced by changes in behavioral parameters such as reduced paw licking, increased rearings, and enhanced crossings. The NPs treatment significantly attenuated the elevated levels of nitrite and restored the reduced glutathione level in the serum of CCI-induced rats. Moreover, histopathological analysis exhibited regeneration of the sciatic nerve injury through reducing myelin degeneration, axonal swelling, and nerve fiber derangement. Therefore, these findings suggest that the naringin-loaded chitosan NPs has promising pharmacological activities for the treatment of neuropathic pain sufferers.
Dealing with green tides on Brittany and Florida coasts.

For over a decade the European Commission has funded programs aimed at examining the problems of algae production, utilization and green tides. COST and BRIDGE led to publication of two volumes surveying the situation, principally on the Atlantic and Mediterranean coasts of Europe. Two presenters of this paper were members of the team and co-authors of the books. The volumes center on Europe and the presenters were principally concerned with the eutrophication and the bioconversion of seaweeds. Research has led to a series of proposals to alleviate the accumulation of stranded algae, mostly Ulva, and their disposal or, at least partial, utilization in agriculture, industry and even energy production. The paper reviews and summarizes their conclusions, several not yet published, putting the accent on the methanization, and draws a parallel with a prevailing situation in Southeastern Florida. Related topics include: Anaerobic digestion of Ulva, Bioconversion of algae, Composting of Ulva, Management of eutrophication, and the “seaweeds” programs of the European Commission.
Urban tourism and its discontents: an introduction

Across the globe, from established tourist cities to less traditional urban destinations, mounting evidence points to an increasing politicization of what hitherto had been a minor issue in urban political struggles. This politicization of urban tourism manifests itself in different ways: local residents may take issue with tourism and its impacts as such; while other contestations revolve around broader processes and forces of urban change of which tourism is only a part. This introductory chapter establishes the context for the rise of urban tourism as a key component of urban development strategies, as a powerful force of urban change and as a source of contention. It contends that the subject matter of ‘protest and resistance in the tourist city’ is often best understood as part of broader struggles and urban social movements surrounding contemporary urban restructuring and governance patterns. It presents a brief taxonomy of the conflicts and contestations surrounding tourism that can be observed in the cities of the Global North and South covered by the subsequent chapters of the volume.
Hybrid Optimization for High Aspect Ratio Wings with Convolutional Neural Networks and Squirrel Optimization Algorithm

An efficient hybrid optimization algorithm is introduced in this paper to optimize the lightweight design of high-aspect-ratio wings, tackling the complexities associated with the mixed optimization design of layout and size variables within these wing structures. A hybrid binary unified coding description facilitates the optimization process for layout and size variables. The study influences one-dimensional convolutional neural networks to establish an aeroelastic surrogate model, primarily chosen for their exceptional performance in handling multi-parameter aeroelastic regression problems. Additionally, the squirrel optimization algorithm is chosen over the genetic algorithm for the mixed optimization problem, leading to notable savings in computational costs. The research demonstrates that the proposed hybrid optimization method, integrating the one-dimensional convolutional neural network and the squirrel optimization algorithm, offers superior performance in optimizing high aspect ratio wings. Specifically, it results in a reduction of 4.1% in the weight of the wing structure. Moreover, the study highlights the necessity of this hybrid approach due to the observed coupling between the layout variables of the wing ribs and the size variables of the wing beams.
Evaluation of Antibacterial, Antioxidant, Anti-inflammatory and Anticancer Efficacy of Titanium-Doped Graphene Oxide Nanoparticles

Introduction: The current development of nanoparticles (NPs) with significant antibacterial properties, low cost and low toxicity has made it possible to develop novel techniques for treatments in the medical field. The titanium metal oxide, when combined with a carbonaceous material like graphene, which has excellent absorbing capacity, is efficient in loading drugs and thus helps in drug delivery and also in biomedical applications like anticancer, anti-inflammatory, antioxidant, and antibacterial activities. Materials and methods: Titanium-doped graphene oxide nanoparticles (Ti/GO-NPs) were processed by the one-pot synthesis method; further characterization was performed by using UV-visible spectroscopy, Fourier transform-infrared spectroscopy (FT-IR), field emission electron microscopy (FE-SEM), and energy-dispersive X-ray spectroscopy (EDX) analysis and biomedical applications like anticancer, anti-inflammatory, antioxidant and antibacterial activities. Results: The synthesized end product of Ti/GO-NPs showed a creamy white appearance. Subsequent characterization studies of UV-Vis spectroscopy revealed a peak level of 373 nm at 24 hours and 404 nm after 48 hours. FT-IR analysis exhibited a broad absorption band within the range of 1000-3500 cm-1, which was attributed to various chemical compounds of C-Br, C-I stretching, C=C bending, S=O stretching, O=H stretching, C=C stretching, H bonded and OH stretching to different absorbance wavelength ranges. SEM analysis exhibited quasi-spherical-shaped Ti/GO-NPs with an average particle size of 50- 100 nm and EDX analysis showed the elemental composition of 32.3% titanium 43.9% oxygen and 2.5% carbon. The antibacterial activity showed moderate activity against Staphylococcus aureus and no activity against Pseudomonas aeruginosa, Enterococcus faecalis and E. coli. The antioxidant activity exhibited 88% at 50 µg/mL concentration, the anti-inflammatory activity revealed 80% at 80 µg/mL concentration and the anticancer activity showed 21% at 150 µg/mL concentration. Conclusion: The characterization and biomedical application conclude that a combination of Ti/GO-NPs will be efficient in drug delivery. The study showed moderate antibacterial activity and significant antioxidant, anti-inflammatory and anticancer activities. Considering their physiochemical properties, absorption capacity and mechanism of drug delivery, Ti/GO-NPs can be incorporated into various applications in the medical field.