Miracle-dz/UniFAR-FTUs huggingface dataset:
Association of serum laboratory parameters with periprocedural myocardial infarction after a primary percutaneous coronary intervention

Background Periprocedural myocardial infarction (PMI) is one of the mortality-related complications of percutaneous coronary intervention (PCI) and significantly affects short- and long-term adverse outcomes and immediate cardiovascular events. Our present study aimed to evaluate the association of preprocedural serum laboratory parameters and PMI in patients who received primary PCI and attempted to provide detailed data on the predictors of PCI-related PMI. Methods A total of 1184 consecutive coronary artery disease (CAD) patients who received primary and elective PCI between July 2015 and June 2017 were included and divided into control group and PMI group. The data of serum laboratory parameters were collected from the electronic database of Meizhou People’s Hospital. Results The results indicated that preprocedural fasting blood glucose were higher in PMI group compared with the control group (p < .001). Patients with prior hyperlipidemia were more likely to have experienced PCI-related PMI (p = .018) and the preprocedural level of total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), non-HDL-C, apolipoprotein B (Apo B), and LDL-C/high density lipoprotein cholesterol (HDL-C) were significantly enhanced in PMI group (p < .001). Multivariate regression analysis revealed that preprocedural fasting blood glucose > 6.11 mmol/L (p < .001, OR = 1.949, 95% CI: 1.444–2.630) and LDL-C levels ≥130 mg/dL (p = .005, OR = 1.941, 95% CI: 1.217–3.098) independently predicted PCI-related PMI. Conclusion Our results indicated preprocedural fasting blood glucose >6.11 mmol/L and LDL-C levels ≥130 mg/dL may be useful predictors for PCI-related PMI. The study may provide a detailed data on the predictors of PCI-related PMI.
Three Dimensional Nanowire Array Piezo-phototronic and Piezo-photo-magnetotronic Sensors

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The ultra high sensitivity blood counter: a compact, MRI-compatible, radioactivity counter for pharmacokinetic studies in μl volumes

Quantification of physiological parameters in preclinical pharmacokinetic studies based on nuclear imaging requires the monitoring of arterial radioactivity over time, known as the arterial input function (AIF). Continuous derivation of the AIF in rodent models is very challenging because of the limited blood volume available for sampling. To address this challenge, an Ultra High Sensitivity Blood Counter (UHS-BC) was developed. The device detects beta particles in real-time using silicon photodiodes, custom low-noise electronics, and 3D-printed plastic cartridges to hold standard catheters. Two prototypes were built and characterized in two facilities. Sensitivities up to 39% for 18F and 58% for 11C-based positron emission tomography (PET) tracers were demonstrated. 99mTc and 125I based Single Photon Emission Computed Tomography (SPECT) tracers were detected with greater than 3% and 10% sensitivity, respectively, opening new applications in nuclear imaging and fundamental biology research. Measured energy spectra show all relevant peaks down to a minimum detectable energy of 20 keV. The UHS-BC was shown to be highly reliable, robust towards parasitic background radiation and electromagnetic interference in the PET or MRI environment. The UHS-BC provides reproducible results under various experimental conditions and was demonstrated to be stable over days of continuous operation. Animal experiments showed that the UHS-BC performs accurate AIF measurements using low detection volumes suitable for small animal models in PET, SPECT and PET/MRI investigations. This tool will help to reduce the time and number of animals required for pharmacokinetic studies, thus increasing the throughput of new drug development.
Skin occlusive performance: Sustainable alternatives for petrolatum in skincare formulations

The emollients are important ingredients used in skincare formulations that can act as moisturizing agents through their occlusive potential, preventing skin water loss. Consumer interest in natural and sustainable products has grown considerably in the last few years, requiring efforts from the cosmetic industry to design products with raw materials of natural, organic, and sustainable origin. Thus, it is essential to improve the knowledge about the behavior of cosmetic raw materials that can be used as sustainable alternatives to synthetic ingredients.
Ultrastructural adaptation of the oropharyngeal cavity of the Eurasian common moorhen (Gallinula chloropus chloropus): Specific adaptive dietary implications

The present investigation represents the first morphological description of the oropharyngeal cavity of Eurasian common moorhen. Nine oropharyngeal cavities were examined grossly and by stereomicroscope and scanning electron microscopic (SEM) observations. The tongue had a rounded apex with multiple acicular processes on its rostral and lateral borders. The dorsal lingual surface of the apex and body had a median sulcus. The papillary crest carried four caudally directed triangular conical papillae on its median part and four triangular conical papillae on each lateral part. The filiform papillary system; small papillae on apex and long papillae on the rostral part of the body while broad papillae on the caudal part of the body. The lingual root had a special appearance by presence of three areas: mucosal fossa, two lateral ridges, and rhomboidal elevated central part. The caudal border of the mound carried heart‐shaped pharyngeal papillae that possessed three papillary rows. The palate had a median palatine ridge rostrally that surrounded by two lateral palatine ridges. The choanae had two equal parts: rostral tapering and wide caudal. The rostral tapering choanal part was surrounded by two longitudinal rows of caudally directed conical papillae, one on each side. There was a single transverse row of conical papillae on each side of the caudal part of the rostral tapering choanal part. The caudal wide choanal part did not encircle by any papillae. Our conclusion exhibited unique structural and functional specifications of the oropharyngeal cavity with the tongue that evident with nutritional behavior.
SAFETY BENEFITS OF THE SEAT BELT LEGISLATION AND SPEED LIMIT REDUCTION IN ONTARIO

In January 1976, legislation became effective requiring the use of seat belts. In February 1976, the seat belt legislation was enforced for the first time and speed limits were lowered on many of the major highways. This paper will examine the evidence that shows that both seat belts and lower speed limits have been effective in reducing injuries and saving lives. Included will be the trends in observed seat belt use, trends in travel speeds, fatality and injury rates with and without belts, accident statistics on highways where the speed limit was lowered as compared with highways where the speed limit was not lowered, and fatality and injury rates for vehicle occupants as compared with other motor vehicle accident victims.
Effect of heat stress on ileal microbial community of indigenous yellow‐feather broilers based on 16S rRNA gene sequencing

Abstract Objectives The broiler chickens are susceptible to heat stress (HS), including the indigenous broilers raised in tropical and subtropical regions. HS caused intestinal dysfunction and disrupted the gut microbiota. However, the researches about the effects of HS on ileal microbiome of indigenous broilers are limited. Therefore, this experiment used 16S rRNA sequencing to analyse the ileal microbial community in indigenous yellow‐feather broilers under HS. Material and methods The single factor completely random design was used in the present study, and forty 8‐week‐old Chinese indigenous yellow‐feather broilers (Huaixiang chickens) were randomly divided into two treatments: normal temperature (NT) group and HS group. There are five replications with four broilers per replicate in each group. The broilers in NT group were raised at 21.3 ± 1.2°C during the whole experimental period, the broilers in HS group were exposed to 32.5 ± 1.4°C for 8 h/day from 9:00 am to 17:00 pm and the temperature of rest time is consistent with NT group. The experiment lasted for 4 weeks. Results The results showed that HS exposure had no significant effects on the alpha diversity index of ileal microflora of broilers, including the Shannon, Simpson, Chao1 and ACE indexes (p > 0.05). At the genus level, HS significantly reduced the relative abundance of Campylobacter (p < 0.05), and increased the abundance of Delftia (p < 0.05). In addition, prediction of microbial community function indicated that HS significantly enhanced the abundance of the microflora related to lipid metabolism, carbohydrate metabolism and xenobiotics biodegradation and metabolism and reduced the abundance of the microflora related to nucleotide metabolism and amino acid metabolism. Conclusions Taken together, the present study revealed that chronic HS (4 weeks) exposure changes the abundance of the ileal microflora of broilers. These findings provided new insights into the role of HS in influencing ileal microbial community in indigenous broilers.
Different Medium of Instruction, Different Destiny of Language Shift? A Pilot Study in Kuala Lumpur

As a multiracial and multilingual society, Malaysia employs bilingual/trilingual education system. At secondary level, there are three different types of schools in terms of medium of instruction (hereafter MOI). To explore the relationship between MOI and language use, language attitude, and further language shift among Chinese students, two questionnaire surveys are designed. The 423 respondents come from Confucian Private Secondary School with Mandarin as MOI and SMJK Confucian which adopts Malay as MOI in Kuala Lumpur respectively. The results show that students from the Chinese medium school maintain more Chinese dialects, such as Hakka and Minnan dialect, and hold more positive attitude towards them compared to those from Malay medium school. However, minor dialects such as Chaoshan dialect, Fuqing dialect, and Qiongwen dialect are loosing ground for both groups. As for the use of Mandarin and Cantonese, the dominant dialect in the Chinese community in Kuala Lumpur, in family domain, no significant difference is found between the two groups. To conclude, Chinese students from the Malay medium school are experiencing a rapid language shift towards Cantonese and Mandarin, while students from the Chinese medium school show a stronger degree of maintenance of Chinese major dialects.
A SIMPLIFIED GAS-LIQUID FLOW MODEL FOR KICK MITIGATION AND CONTROL DURING DRILLING OPERATIONS

Real-time estimation of annular pressure profile and formation pressure is crucial for the execution and planning of a well control operation, especially when drilling formations with narrow pore and fracture pressure margins. A simple transient multi-phase simulator, capable of accurately representing gas and liquid dynamics while minimizing complexity and computational requirements, is highly desirable for real-time kick mitigation and control applications. Such a simulator is presented here in the form of a coupled ODE-PDE model composed of a first order ODE and a first order hyperbolic PDE. This model is shown to retain the dominating two-phase dynamics encountered during gas kick incidents. As a particular application, we demonstrate the use of the model in design of switched control algorithms for kick handling in a Managed Pressure Drilling setting. A Recursive Least Squares algorithm is employed for estimation of unknown model parameters.Copyright © 2015 by ASME
Plant growth-promoting properties of bacterial endophytes isolated from roots of Thymus vulgaris L. and investigate their role as biofertilizers to enhance the essential oil contents

Abstract The main objective of the current study was to improve the essential oil contents of Thymus vulgaris L. using bio-inoculation with bacterial endophytes. Therefore, out of fourteen endophytic bacterial isolates obtained from roots of T. vulgaris, five isolates were selected based on the highest nitrogen-fixation and phosphate solubilization activity and identified as: Bacillus haynesii T9r, Citrobacter farmeri T10r, Bacillus licheniformis T11r, Bacillus velezensis T12r, and Bacillus velezensis T13r. These five strains have been recorded as ammonia, hydrogen cyanide (HCN), siderophores, and indole-3-acetic acid (IAA) producers. These strains have the efficacy to fix-nitrogen by reduction of acetylene with values of 82.133±1.4–346.6±1.4 n-mole-C2H4/ml/24 h. The IAA, gibberellic acid, abscisic acid, benzyl, kinten, and ziaten production were confirmed using HPLC. Two strains of T11r and T13r showed the highest plant growth-promoting properties and were selected for bio-inoculation of T. vulgaris individually or in a consortium with different mineral fertilization doses (0, 50, 75, and 100%) under field conditions. The highest growth performance was attained with the endophytic consortium (T11r+T13r) in the presence of 100% mineral fertilization. The GC-MS analysis of thyme oil contents showed the presence of 23 various compounds with varying percentages and the thymol fraction represented the highest percentages (39.1%) in the presence of the bacterial consortium.
The contribution of itch and skin severity improvements to the Dermatology Life Quality Index in patients with atopic dermatitis in baricitinib phase III trials

With data from three monotherapy baricitinib phase III randomized clinical trials (RCTs), we conducted a posthoc mediator analysis to assess whether changes in itch or skin severity mediated the treatment effect over placebo on changes in health‐related quality of life. In this analysis, baricitinib demonstrated significant improvement in the Dermatology Life Quality Index for which itch mediated approximately half of the changes at weeks 4 and 16.
Experimental Investigations on New Characterization Method for Giant Piezoresistance Effect and Silicon Nanowire Piezoresistive Detection

This paper presents a novel and effective characterization method for giant piezoresistive properties of silicon nanowires by using the reference structures. This contrast detection approach investigates the influences of quantum size effect and surface defects effect on piezoresistive coefficients of silicon nanowires by direct comparison of the resistivity change ratio of silicon wires with nanoscale-to-microscale width under the same applied stress conditions. The characterization experiments based on four-point bending tensile test demonstrate that piezoresistive coefficient of small nanowidth silicon nanowire can be significantly increased to about five times higher levels than that of bulk silicon under the same impurity concentration, which indicates that the silicon nanowire can have giant piezoresistive effect. On the other hand, to solve the problem on nanowires pick-up, we proposed a nanowire piezoresistive detection approach, whose validity is confirmed by the dynamic LDV resonance test. Meanwhile, to investigate the influence of undercut arising from the wet chemical release process of the suspended silicon nanowire, a three-dimensional finite element simulation is also carried out for the fundamental resonant frequency using ANSYS software. The numerical and experimental results show that our piezoresistive detection is accurate and effective and the undercut should be carefully considered in the design of the high frequency resonator and mixer. The findings of this paper provide some useful references for the piezoresistive effect measurement and the piezoresistive pick-up in nanoelectromechanical system.
Using methanol to preserve retinas for immunostaining

Experimental studies on retinal vasculature and retinal ganglion cells (RGCs) investigating the developmental and pathological conditions of the retina mainly rely on whole‐mount retinal immunostaining. Methanol, an auxiliary fixed medium for retinal whole‐mount preparations, has been used in some studies; however, its application in short‐ and long‐term storage of retinas for further study has not been well described. We aimed to evaluate methanol use as a preservation treatment for further immunostaining of the retina.
Closed-loop evaluation of Vehicle Stability Control (VSC) systems using a combined vehicle and human driving model

This paper presents a closed-loop evaluation of the Vehicle Stability Control (VSC) systems using a vehicle simulator. Human driver-VSC interactions have been investigated under realistic operating conditions in the laboratory. Braking control inputs for vehicle stability enhancement have been directly derived from the sliding control law based on vehicle planar motion equations with differential braking. A driving simulator which consists of a three-dimensional vehicle dynamic model, interface between human driver and vehicle simulator, three-dimensional animation program and a visual display has been validated using actual vehicle driving test data. Real-time human-in-the loop simulation results in realistic driving situations have shown that the proposed controller reduces driving effort and enhances vehicle stability.
WeatherProof

As part of the Lovely Weather project, artist and environmental scientist Antony Lyons undertook a rural science and art residency project examining the relationships between the locality of the River Finn Valley, County Donegal, Ireland and the processes of climate change. The local countryside is, in many ways, enmeshed in the wider global systems. At the core of the project was the quest for new avenues of communication and dialogue—through revealing unseen and metaphorical connections—enabling the local community and others to engage with the global issues, and the science, in a meaningful way. A research-based ‘deep-mapping’ approach was used. Art installations were developed, and there now exists a platform for some locally grounded sustainable development initiatives to emerge.
Plural Planning at Multiple Scales: From Local Communities to Statewide Change

This case study examines an eight-year trans-disciplinary action research initiative involving an academic planning and design research center and a state agency working in collaboration with other state agencies, nonprofit organizations, and communities. The primary goal of this collaboration was to help communities across New York State change the way they engage in community planning so as to improve the likelihood that investments of people, time, and financial resources result in revitalization. Through a series of linked projects, the questions addressed by the cases shifted in scale from individual community-based projects, to a series of demonstration projects in multiple communities, to a statewide community education program. Outcomes included policy and program changes at the state level as well as positive change and action for individual communities. The collaborative process presented challenges as it grew in scale and complexity. A discussion of the lessons learned reflects on the importance of acknowledging the effect of changes occurring over long-term collaboration, establishing a collaborative framework, and recognizing differences in mission and culture.
PerPaDa: A Persian Paraphrase Dataset based on Implicit Crowdsourcing Data Collection

In this paper we introduce PerPaDa, a Persian paraphrase dataset that is collected from users’ input in a plagiarism detection system. As an implicit crowdsourcing experience, we have gathered a large collection of original and paraphrased sentences from Hamtajoo; a Persian plagiarism detection system, in which users try to conceal cases of text re-use in their documents by paraphrasing and re-submitting manuscripts for analysis. The compiled dataset contains 2446 instances of paraphrasing. In order to improve the overall quality of the collected data, some heuristics have been used to exclude sentences that don’t meet the proposed criteria. The introduced corpus is much larger than the available datasets for the task of paraphrase identification in Persian. Moreover, there is less bias in the data compared to the similar datasets, since the users did not try some fixed predefined rules in order to generate similar texts to their original inputs.
On the Pohozaev identity for quasilinear Finsler anisotropic equations

∂Ω |∇u|(x, η) dx, where G = g with G(0) = 0 and η is the outward unit normal vector to the boundary ∂Ω. Important extensions and further developments can be found in the literature. We recall here the first result in the quasilinear setting [15] where the authors obtained a corresponding identity for smooth C extremals of general variational problems, including results for systems and higher order operators. Since in general, e.g. for the p-Laplacian, solutions are not of class C, we may consider very important the improvement of the results in [15] obtained in [8], where the authors proved the Pohozaev identity for C solutions of general quasilinear Dirichlet problems, by mean of a suitable and technical approximation argument. See also the contribution in [11]. Although to our purposes we could also try to follow the technique of [8], we have to consider the fact that the adaptation to the anisotropic case of such a technique is completely non trivial. On the contrary, by means of fine regularity results, we shall follow a more simple a direct proof.
Explainability Tools Enabling Deep Learning in Future In-Situ Real-Time Planetary Explorations

Deep learning (DL) has proven to be an effective machine learning and computer vision technique. DL-based image segmentation, object recognition and classification will aid many in-situ Mars rover tasks such as path planning and artifact recognition/extraction. However, most of the Deep Neural Network (DNN) architectures are so complex that they are considered a 'black box‘. In this paper, we used integrated gradients to describe the attributions of each neuron to the output classes. It provides a set of explainability tools (ET) that opens the black box of a DNN so that the individual contribution of neurons to category classification can be ranked and visualized. The neurons in each dense layer are mapped and ranked by measuring expected contribution of a neuron to a class vote given a true image label. The importance of neurons is prioritized according to their correct or incorrect contribution to the output classes and suppression or bolstering of incorrect classes, weighted by the size of each class. ET provides an interface to prune the network to enhance high-rank neurons and remove low-performing neurons. ET technology will make DNNs smaller and more efficient for implementation in small embedded systems. It also leads to more explainable and testable DNNs that can make systems easier for Validation & Verification. The goal of ET technology is to enable the adoption of DL in future in-situ planetary exploration missions.