Miracle-dz/UniFAR-FTUs huggingface dataset:
Association and Risk Factors for Hypertension and Dyslipidemia in Young Adults from Poland

Hypertension and dyslipidemia are major risk factors for cardiovascular disease. Studies on the association between abnormal levels of lipids and hypertension have yielded inconsistent results. The aim of this study was to examine the prevalence of hypertension and dyslipidemia and its risk factors in young Polish adults. Furthermore, the association between plasma lipid levels and the risk of hypertension was determined. A cross-sectional study was conducted among 115 volunteer participants. Blood pressure was measured using an automated oscillometric sphygmomanometer. Blood lipids were analyzed from a fasting blood sample received by finger prick. Body fat percentage was assessed using a bioelectrical impedance analysis device. Socioeconomic and lifestyle factors (age, date of birth, place of residence, screen time, and tobacco use) were self-reported by the participant. The prevalence of hypertension was higher in men than in women (61.5 vs. 21.3%). The prevalence of elevated TC, TG, high LDL, and low HDL was 22.6%, 7.8%, 38.3%, and 13.9%, respectively. Spending more than 2 h daily in front of a computer was identified as a significant predictor of hypertension and elevated TG levels (p < 0.05). A high number of cigarettes smoked daily was a significant risk factor for hypertension (p = 0.047). Hypertension contributed to a higher risk of abnormal values of TC (OR = 5.89), LDL (OR = 5.38), and TG (OR = 9.75). Participants with hypertension were more likely than normotensive subjects to have elevated levels of TC, LDL, and TG. The prevalence of hypertension was significantly higher in young men than in women. BMI was associated with the prevalence of hypertension and elevated TC levels. Spending more than 2 h per day in front of a computer contributed to the prevalence of hypertension and elevated TG levels. Participants with hypertension smoked a higher number of cigarettes daily compared to those with normotension.
In Vitro and In Silico Biological Studies of 4-Phenyl-2-quinolone (4-PQ) Derivatives as Anticancer Agents

Our previous study found that 2-phenyl-4-quinolone (2-PQ) derivatives are antimitotic agents, and we adopted the drug design concept of scaffold hopping to replace the 2-aromatic ring of 2-PQs with a 4-aromatic ring, representing 4-phenyl-2-quinolones (4-PQs). The 4-PQ compounds, whose structural backbones also mimic analogs of podophyllotoxin (PPT), maybe a new class of anticancer drugs with simplified PPT structures. In addition, 4-PQs are a new generation of anticancer lead compounds as apoptosis stimulators. On the other hand, previous studies showed that 4-arylcoumarin derivatives with 5-, 6-, and 7-methoxy substitutions displayed remarkable anticancer activities. Therefore, we further synthesized a series of 5-, 6-, and 7-methoxy-substituted 4-PQ derivatives (19–32) by Knorr quinoline cyclization, and examined their anticancer effectiveness. Among these 4-PQs, compound 22 demonstrated excellent antiproliferative activities against the COLO205 cell line (50% inhibitory concentration (IC50) = 0.32 μM) and H460 cell line (IC50 = 0.89 μM). Furthermore, we utilized molecular docking studies to explain the possible anticancer mechanisms of these 4-PQs by the docking mode in the colchicine-binding pocket of the tubulin receptor. Consequently, we selected the candidate compounds 19, 20, 21, 22, 25, 27, and 28 to predict their absorption, distribution, metabolism, excretion, and toxicity (ADMET) profiles. Pharmacokinetics (PKs) indicated that these 4-PQs displayed good drug-likeness and bioavailability, and had no cardiotoxic side effects or carcinogenicity, but we detected risks of drug–drug interactions and AMES toxicity (mutagenic). However, structural modifications of these 4-PQs could improve their PK properties and reduce their side effects, and their promising anticancer activities attracted our attention for further studies.
Model equations for waves in stratified fluids

Model equations for gravity waves in horizontally stratified fluids are considered. The theories to be addressed focus on stratifications featuring either a single pycnocline or neighbouring pairs of pycnoclines. Particular models investigated include the general version of the intermediate long-wave equation derived by Kubota, Ko and Dobbs to simulate waves in a model system consisting of two homogeneous layers separated by a narrow region of variable density, and the related system of equations derived by Liu, Ko and Pereira for the transfer of energy between waves running along neighbouring pycnoclines. Issues given rigorous mathematical treatment herein include the well-posedness of the initial value problem for these models, the question of existence of solitary wave solutions, and theoretical results about the stability of these solitary waves.
Influence of the Enzymatic Hydrolysis Using Flavourzyme Enzyme on Functional, Secondary Structure, and Antioxidant Characteristics of Protein Hydrolysates Produced from Bighead Carp (Hypophthalmichthys nobilis)

In the current study, bighead carp fish were used in conjunction with the flavourzyme enzyme to obtain (FPH) fish protein hydrolysates. The optimum conditions of the hydrolysis process included an enzyme/substrate ratio of 4% and a temperature of 50 °C and pH of 6.5. The hydrolysis time was studied and investigated at 1, 3, and 6 h, and the (DH) degree of hydrolysis was recorded at 16.56%, 22.23%, and 25.48%, respectively. The greatest yield value was 17.83% at DH 25.48%. By increasing the DH up to 25.48%, the crude protein and total amino acid composition of the hydrolysate were 88.19% and 86.03%, respectively. Moreover, more peptides with low molecular weight were formed during hydrolysis, which could enhance the functional properties of FPH, particularly the solubility property ranging from 85% to 97%. FTIR analysis revealed that enzymatic hydrolysis impacted the protein’s secondary structure, as indicated by a remarkable wavelength of amide bands. Additionally, antioxidant activities were investigated and showed high activity of DDPH radical scavenging, and hydroxyl radical scavenging demonstrated remarkable activity. The current findings demonstrate that the functional, structural, and antioxidant characteristics of FPH might make it an excellent source of protein and suggest potential applications in the food industry.
Laser ablation and column formation in silicon under oxygen-rich atmospheres

The microstructure formed at the surface of silicon by cumulative pulsed-laser irradiation in oxygen-rich atmospheres consists of an array of microcolumns surrounded by microcanyons and microholes. Formation of SiOx at the exposed surface of silicon is most likely responsible for the occurrence of etching/ablation that causes the continuous deepening of canyons and holes. The growth mechanism of columns that is supported by the experimental evidence presented here is a process in which the columns are fed at their tips by the silicon-rich ablation plasma produced during pulsed-laser irradiation.
Ray-space coding based on arbitrarily shaped DCT

The Ra-Space method proposed by us is one of the key tools which can be applied to wide areas of 3D image processing and handling. It will contribute to the creation of 3D spatial communication and virtual societies. The Ray-Space is defined as the intensity function F(P), where P represent 4D ray parameters. In this paper, we present a novel Ray- Space coding scheme using an arbitrary-shaped DCT. This scheme consists of the following two steps. The Ray-Space data is first segmented into quadrilateral-shaped primitives. Then, the texture data in each primitive is coded by the arbitrary-shaped DCT. In the experiment, the coding performance of the proposed scheme was examined. The results shows that the proposed coding scheme shows the better coding performance than the block-based Ray-Space coder.
Parameter of Nonlinearity in Fluids

The sound velocity has been measured as a function of temperature and hydrostatic pressure for a number of organic liquids and for water‐methanol mixtures. These data have been used to compute the ratio B/A of the coefficient B of the quadratic term to that of the linear term A in the adiabatic expansion of pressure changes in terms of density changes. The ratio has also been computed (by use of data from other sources) for sea water and for five alcohols. A discussion is given of various methods of computing B/A.
Behavior of Asymptotically Flat Empty Spaces

The asymptotic behavior of the Weyl tensor and metric tensor is investigated for probably all asymptotically flat solutions of the empty space Einstein field equations. The systematic investigation utilizes a set of first order differential equations which are equivalent to the empty space Einstein equations. These are solved asymptotically, subject to a condition imposed on a tetrad component of the Riemann tensor ψ0 which ensures the approach to flatness at spatial infinity of the space‐time. If ψ0 is assumed to be an analytic function of a suitably defined radial coordinate, uniqueness of the solutions can be proved. However, this paper makes considerable progress toward establishing a rigorous proof of uniqueness in the nonanalytic case. A brief discussion of the remaining coordinate freedom, with certain topological aspects, is also included.
The Three Gap Theorem (Steinhaus Conjecture)

Abstract This paper is concerned with the distribution of N points placed consecutively around the circle by an angle of α. We offer a new proof of the Steinhaus Conjecture which states that, for all irrational α and all N, the points partition the circle into arcs or gaps of at least two, and at most three, different lengths. We then investigate the partitioning of a gap as more points are included on the circle. The analysis leads to an interesting geometrical interpretation of the simple continued fraction expansion of α.
Antihypertensive activity of Lugwigia octovalvis (Jacq.) P. H. Raven (Onagraceae) hydro alcoholic extract on rat

Our objective was to study the activity of Ludwigia octovalvis hydro alcoholic extract in rats made experimentally hypertensive by a hypersodic diet. After 21 days of this diet, the systolic and diastolic blood pressure of these animals increases to 200.1 ± 1.5 / 155.6 ± 1.5 mm Hg, respectively. Administered orally, the extract reduces this high blood pressure. The control group blood pressure returned to its normal value (113.2 ± 1.2/76.3 ± 1) mm Hg after 24 days, versus 9th, 15th and 19th days for animals treated with the extract at doses of 400, 200 and 100 mg / kg (P <0.05). It does not have any diuretic activity but relaxes the isolated aorta contracted with norepinephrine 10-4 M with an EC50 equal to 1.18 ± 0.02 mg/ml. These results indicate that Ludwigia octovalvis extract has an antihypertensive activity by its vasodilator property. The polyphenols, triterpenoids and flavonoids in the extract may be responsible for its hypotensive activity.
The IRAS bright galaxy sample. V. Multibeam photometry of galaxies with L(IR) greater than 10 to the 11th solar luminosities

With a view to studying the spatial distribution of the near-IR emission in luminous IRAS galaxies, 47 galaxies with IR luminosities greater than 10 to the 11th solar luminosities have been measured at 1.3, 1.65, and 2.2 microns with beam diameters of 17, 33, and 55 arcsec, and used in conjunction with 5 and 10 arcsec observations. the unusually red near-IR colors are found to be confined to the nuclear regions, while the outer disk regions have near-IR colors appropriate to a normal stellar population. Since most of the IR luminosity is coming from the nuclei, the global near-IR properties of IR luminous galaxies are not good tracers of IR activity. 36 refs.
Acoustic radiation force on a small compressible sphere in a focused beam

A general expression for the acoustic radiation force on a small compressible sphere has been derived and expressed in terms of the time‐averaged densities Ti and Vi of kinetic and potential energies, respectively, in the incident sound field. The results have been applied to two focused beams: Gaussian beams and piston beams. For both cases, the analytical expressions of the radiation forces on a small compressible sphere placed on the axis of the beams are calculated. The pertinent applications in acoustic levitation and bubble dynamics are discussed.
Protocol Design for Surveillance of Risk Factors of Non–communicable Diseases During the COVID-19 Pandemic: An Experience from Iran STEPS Survey 2021

Background: Regarding the growing burden of non-communicable diseases (NCDs) and exposure to their risk factors, and the continuous need for nationwide data, we aimed to develop the latest round of the STEPwise Approach to NCD Risk Factor Surveillance (STEPS) survey in 2021 in Iran, while the COVID-19 pandemic was still present. Methods: In addition to the three main steps of this survey, including questionnaires, physical measurements, and laboratory assessments, we adapted the survey with the situation caused by the COVID-19 pandemic, by adding to various aspects of study phases and changing some scientific and executive procedures in this round of STEPS survey in Iran. These changes were beyond the initial novelties embedded within the survey before the pandemic, by refining the study protocol benefiting from the previous experiences of the STEPS survey. Results: By amending the required changes, we could include a total of 27874 individuals in the first step of the survey. This number was 27745 and 18119 for the second and third steps. Comparing the preliminary results with the previous nationwide surveys, this study was highly representative on both national and provincial levels. Also, implementing the COVID-19 prevention and control strategies in all stages of survey led to the least infection transmission between the study investigators and participants. Conclusion: The novel initiatives and developed strategies in this round of Iran STEPS survey provide a state-of-the-art protocol for national surveys in the presence of an overwhelming catastrophe like the COVID-19 pandemic and the triggered limitations and shortages of resources.
Free energy and emittance growth in nonstationary charged particle beams

Charged particle beams that are not perfectly matched or centered when injected into a focusing channel (or accelerator) have a higher total transverse energy than the equivalent ideal stationary beam. The excess energy ΔE represents free energy that can cause emittance growth. A general relationship between the possible emittance growth and ΔE is derived, and analytical results are presented for nonuniform, mismatched, and off‐centered beams.
A compact L-band Ortho Mode Junction

We describe the design construction and performance of a L-band (1300-1800 MHz) Ortho Mode Junction for the L-P dual-band receiver to be installed on the 64 m Sardinia Radio Telescope (SRT), a new radio telescope which is being built in Sardinia, Italy. The Ortho Mode Junction (OMJ) separates two orthogonal linearly polarized signals propagating in a 172 mm diameter circular waveguide and couple them into four coaxial outputs. The OMJ is part of an OMT (Ortho Mode Transducer), which includes two 1800 hybrids allowing to recombine the out-of-phase signals from the balanced OMJ outputs. The OMJ consists of four probes arranged in symmetrical configuration across the circular waveguide. A shaped tuning stub with cylindrical profile is placed a quarter wavelength away from the probes to guarantee broadband operation with low reflection coefficient across L-band. The four identical probes have a cylindrical structure, each consisting of three concentric cylinders that attach to the central pin of standard 50 Ω 7/16-type coaxial connectors. The OMJ will be cooled at 80 K inside a compact dewar together with directional couplers and Low Noise Amplifiers. The two linearly polarized signals from an input 190 mm diameter room temperature L-band feed couple into the cryogenic dewar through a vacuum window located across the waveguide. Inside the dewar, the 190 mm diameter circular waveguide is tapered down to 172 mm using a conical transition (length 85 mm) filled with a Styrodur® foam that provides mechanical support for a 0.125 mm thick Kapton vacuum barrier. A 0.6 mm air gap across the 172 mm circular waveguide provides thermal decoupling between the ambient temperature and the 80 K OMJ, which is connected to the conical transition output.
LOW-FREQUENCY ADSORBATE VIBRATIONAL RELAXATION AND SLIDING FRICTION

We present a study of the damping (energy relaxation) of low-frequency adsorbate vibrational modes via one-phonon emission. The dependence of the damping rate on the size of the adsorbates, the adsorbate coverage, and the nature of the (nonphononic) adsorbate-adsorbate interactions has been studied. We show that different experimental probing techniques, e.g., inelastic helium scattering or time-resolved adsorbate response to substrate heating, probe different damping rates. We also show that the energy relaxation rate may be strongly affected by (pure) dephasing processes. Experimental data are presented and compared to the theoretical results. Finally, we show that the phononic friction vanishes for incommensurate layers sliding on solid surfaces and present a discussion about the nature of the surfaces used in recent measurement of the sliding friction on superconducting lead surfaces.
Detection and classification using higher-order statistics of optical matched filters

In this paper we consider the problem of detection and classification of signals in the presence of additive Gaussian noise of unknown covariance (AGN/TJC), using higher than second-order statistics (HOS) of the output of a matched filter. Specifically, we apply the HOS-based method developed in [1,2] to phase-only matched filters. The main result of this paper is that the HOSbased statistic is appropriate for use with phase-only matched filter (POMF) outputs. Simulation results are presented which indicate the ability of the matched filter and the POMF, which are augmented with 1105, to detect a 2-d signal at signal-to-noise ratios below which the matched filters alone are incapable of making a detection.
Varieties of Illiberal Backlash in Central Europe

ABSTRACT Abortion, same-sex marriage, gender equality, and LGBTQ rights have become hotly contested topics in Central Europe over the past two decades. Abortion rights have been rolled back, and the expansion of LGBTQ rights has been stalled or reversed. What explains the varieties of illiberal backlash in Central Europe? We argue that the extent of backlash reflects the strength of an alliance between socially conservative advocacy groups and political parties. However, we also show two factors curbing illiberal backlash: public opinion and a pluralistic moderate confessional political party. Both factors constrain illiberal politicians and dampen the radicalization of parties in power.
Cold dark matter candidates and the solar neutrino problem

Certain currently proposed weakly interacting elementary particles can have a high probability of solar capture if they make up the Galactic halo. Their present abundance in the Sun is here determined by balancing capture rates against annihilation rates. Both particle physics and cosmological considerations impose constraints on scattering and annihilation cross sections. In general, for the candidate particles here discussed (massive neutrinos, supersymmetric scalar neutrinos, and photinos), the inferred solar abundances are too small by three to four orders of magnitude to solve the solar neutrino problem. Extreme fine tuning, marginally possible in the case of the photino, could increase solar abundances to a level where the neutrino signature would be affected. Otherwise, either a particle with a net cosmological asymmetry, or else a new mechanism for strengthening the existing Majorana suppression of s-wave annihilation at very low energies, would seem to be required.
The Stability of Pipe Entrance Flows Subjected to Axisymmetric Disturbances

This paper reexamines an important unresolved problem in fluid mechanics--the discrepancy between measurements and predictions of stability in pipe entrance flows. Whereas measured critical Reynolds numbers are relatively insensitive to velocity profile shape in the streamwise direction, the theoretical results indicate a rapid increase, both as the equilibrium profile is approached, and toward the inlet. The current work uses the displacement thickness based Reynolds number as a rational basis on which to compare new stability predictions obtained by means of the Q-Z algorithm, with existing theoretical results. Although the present data are shown to be the only data that are consistent with the classical parallel boundary layer limit towards the inlet, they still deviate increasingly with axial distance from the only available experimental results. By examining pipe inlet stability data in relation to boundary layer measurements and predictions, the work effectively questions the commonly held belief that streamwise variations of flow alone are responsible for these deviations, suggesting that the finite amplitude nature of the applied disturbances is the most likely cause.
Hypernormal Form for the Hopf-Zero Bifurcation

In this paper we present hypernormal forms up to an arbitrary order for equilibria of tridimensional systems having a linear degneracy corresponding to a pair of pure imaginary eigenvalues and a third one zero. These simplest normal forms are obtained assuming some generic conditions on the quadratic terms, and using C∞-conjugacy as well as C∞-equivalence. Also, the case of ℤ2-symmetric systems is considered. In this situation, the hypernormal forms are characterized under generic conditions on the cubic terms. In all the cases, we provide recursive algorithms that compute explicitly the hypernormal form coefficients, in terms of the normal form coefficients.
Deep Recurrent Reinforcement Learning-Based Distributed Dynamic Spectrum Access in Multichannel Wireless Networks With Imperfect Feedback

This paper investigates Dynamic Spectrum Access (DSA) paradigm with imperfect feedback for multiuser wireless network. Each user selects an orthogonal channel in particular time slot to transmit packet with a certain transmission probability. In next time slot, the user who has transmitted a packet receives an ACK signal based on local observation. Bearing in mind the dynamic nature of wireless networks, it is appealing to develop a blended strategy to perform effective DSA. This paper aims to design a distributed Deep Reinforcement Learning (DRL) based scheme with an objective of maximizing network utility. In conventional DRL framework, it is assumed that the feedback received (ACK packet) is always correct but in wireless networks, it may be lost or corrupted due to noise. Furthermore, it is challenging to promise that the multiple agents will cooperate to make coherent decisions in order to accomplish the same objective, particularly under imperfect feedback. To tackle these challenges, this work proposes (i) Deep Recurrent Reinforcement Learning network with integrated GRU layer to optimize the network utility function and (ii) a feedback recovery mechanism using complete and incomplete replay buffers. Extensive simulations corroborate the success of proposed scheme in complex multiuser scenario and exhibit robustness against the detrimental effects of the imperfect feedback.
Stable 1 volt programmable voltage standard

Several fully functional programmable voltage standard chips, each having a total of 32 768 Nb–PdAu–Nb Josephson junctions, have been fabricated and tested. The chips are based on a new design that provides fast programmability (1 μs) between voltages and stable voltage operation from −1 to +1 V. A comparison of the new standard with a conventional Josephson voltage standard is in agreement to 0.5±1.1 parts in 109. We demonstrate the utility of this standard by measuring the linearity of a digital voltmeter.