Miracle-dz/UniFAR-FTUs huggingface dataset:
Effects of heat treatment on microstructure and hardness of D2 tools

D2 high chromium tool steel is widely used to produce tools and components that work at significant dynamic loads, such as dies, punch and rollers. The steel must have a good combination of strength and toughness, which heat treatment can obtain. Therefore, this study discusses the effect of normalising, hardening, and tempering on the microstructure and hardness of D2 tools. Normalising and hardening were carried out respectively at 1020°C for 30 minutes, followed by rapid cooling using oil. Tempering was realised by reheating the quenched sample at 250°C and 400°C with variations in holding time of 15 minutes, 30 minutes, and 45 minutes. The hardness of the specimens was measured using a Rockwell hardness tester, whereas the microstructure was observed with an optical microscope. The results indicated that the microstructure changes to martensite and carbide after quenching, while the microstructure becomes tempered martensite and carbide after tempering. Normalising and hardening have almost no impact on hardness, and the increase in temperature and holding time causes a decrease in hardness. The reduction in hardness is noticeable for steels tempered to 400 °C and held for 45 minutes.
ANTXR1 Regulates Erythroid Cell Proliferation and Differentiation through wnt/β-Catenin Signaling Pathway In Vitro and in Hematopoietic Stem Cell

Erythropoiesis is a highly complex and sophisticated multistage process regulated by many transcription factors, as well as noncoding RNAs. Anthrax toxin receptor 1 (ANTXR1) is a type I transmembrane protein that binds the anthrax toxin ligands and mediates the entry of its toxic part into cells. It also functions as a receptor for the Protective antigen (PA) of anthrax toxin, and mediates the entry of Edema factor (EF) and Lethal factor (LF) into the cytoplasm of target cells and exerts their toxicity. Previous research has shown that ANTXR1 inhibits the expression of γ-globin during the differentiation of erythroid cells. However, the effect on erythropoiesis from a cellular perspective has not been fully determined. This study examined the role of ANTXR1 on erythropoiesis using K562 and HUDEP-2 cell lines as well as cord blood CD34+ cells. Our study has shown that overexpression of ANTXR1 can positively regulate erythrocyte proliferation, as well as inhibit GATA1 and ALAS2 expression, differentiation, and apoptosis in K562 cells and hematopoietic stem cells. ANTXR1 knockdown inhibited proliferation, promoted GATA1 and ALAS2 expression, accelerated erythrocyte differentiation and apoptosis, and promoted erythrocyte maturation. Our study also showed that ANTXR1 may regulate the proliferation and differentiation of hematopoietic cells, though the Wnt/β-catenin pathway, which may help to establish a possible therapeutic target for the treatment of blood disorders.
Adaptive Finite Element Methods for Reactive Flow Problems

We present and analyze adaptive finite element methods with reliable and efficient error control for a variety of convection-diffusion-reaction problems. The adaptive methods are based on a posteriori error estimates, where the error is estimated in terms of the residual of the computed solution, the mesh size and multiplicative factors measuring certain stability properties of an associated linearized dual problem. The stability factors are computed numerically by solving the linearized dual problem. We present several computational examples illustrating applications to reaction-diffusion problems and reactive compressible flow.
Determination of user experience on food business websites using neuromarketing techniques

The main purpose of this study is to determine the visual contents that should be used in food business websites by neuromarketing measurement. It is inevitable that the visual content planning to be made on a website will increase the experience performance of the users on that website. In this research, an experimental design was planned, and two websites were created from twenty-eight visual content items obtained from the literature. By creating the experimental procedure, an experimental area was prepared for eight subjects, and websites were shown to them. Electroencephalogram (EEG) and eye-tracking measurements were taken over the websites shown during the experiment. The results revealed that the experiment1 website using structured visual contents was more efficient on attention, higher concentration, and total fixation. The findings revealed that the anxiety level of the experiment2 website, which used unplanned visual contents, was more pronounced for the subjects. In light of the findings obtained in this study, professionals can create visual contents that they use on food business websites much more efficiently.
Dynamics and Population Structure of Bali Cattle Partnerships Maiwa Breeding Center (MBC) in Barru Regency

This study aims to determine the population dynamics, population structure, and increase of Bali cattle population Maiwa Breeding Center partnerships in Barru Regency. This research was conducted from March to April 2020 in Barru Regency, South Sulawesi. The Reproductive Efficiency of Bali cattle was 91%. Population dynamics were only influenced by the calving, mortality, and sale of livestock, with the growth of 27% (2019) and 31% (2020). The population structure was dominated by cows, 31% (2018), 48% (2019), and 54% (2020). Natural Increase (NI) of livestock was 17% (2018), 28% (2019) and 20% (2020). The conclusion of this study is that the growth of the Bali cattle population of MBC partnerships was still low when according to calving and income because it does not reach 80% of cows based on population even shows a tendency to decrease calving. Keywords: Population of dynamics, population of structure, Bali cattle, smallholder partnerships
Abnormalities of the Default Mode Network Functional Connectivity in Patients with Insomnia Disorder

Objective This paper aimed to probe changes in the default mode network (DMN) functional connectivity (DMNFC) of the brain of patients with insomnia disorder (ID) under the resting state. Methods A total of 67 patients with ID and 67 graphically matched healthy controls were selected. Then, their general information was collected, followed by a psychological scale valuation. Resting state functional magnetic resonance imaging (rs-fMRI) scanning was conducted. Subsequently, collected statistics were processed, bilateral precuneus and medial superior frontal gyrus were defined as regions of interest (ROI), and the difference in intensity between these two groups was compared. Results Compared with the healthy control group, the patients in the ID group were observed with abnormalities of DMNFC. Specifically, a significant increase in the functional connectivity (FC) could be observed between the left medial superior frontal gyrus and left central anterior gyrus, the left medial superior frontal gyrus and anterior cingulate gyrus, the right medial superior frontal gyrus and left central anterior gyrus, the left anterior cuneiform and left central anterior/posterior gyrus, the left anterior cuneiform and left superior occipital gyrus, as well as the right anterior cuneiform and left central posterior gyrus. However, the FC between the left anterior cuneiform and the right middle frontal gyrus was weakened, as well as between the left anterior cuneiform and the right angle gyrus and between the right precuneus and the left inferior temporal gyrus. Conclusion ID patients may suffer changes in FC. The decline of FC in DMN may be one of the underlying causes of ID; the enhancement of FC between DMN and the visual-spatial attention network may play a key role in the mechanisms of impaired brain functional networks of ID.
Percutaneous Drainage as The Management of Amebic Liver Abscess (ALA): A Case Report

Background: Amebic liver abscess (ALA) is the most common extraintestinal manifestation of amebiasis caused by Entamoeba histolytica infection. Clinical diagnosis of ALA is often uncertain due to no specific signs and symptoms. Abscess aspiration or drainage had a vital role in the management of ALA, mainly in cases with inadequate treatment response and large abscesses at risk of rupture. Case Presentation: A 66-year-old male patient presented with right upper quadrant abdominal pain for two weeks. He was diagnosed with a liver abscess in another hospital and then referred to our hospital due to inadequate clinical response after the treatment. Ultrasonography showed a solitary hypoechoic lesion in the right lobe of the liver and the CT scan revealed a well-defined hypodense lesion with regular margins in segment VII of the liver. Metronidazole and ceftriaxone were given intravenously during hospitalization. Percutaneous drainage of the liver abscess was performed on the seventh day of hospitalization with the indication of inadequate treatment response, size, and location of the abscess. The culture of the discharge showed growth of E. histolytica. No complications were found and the patient was discharged on the twelfth day of hospitalization with optimal clinical improvement. Conclusion: We report a case of ALA with inadequate response to the conservative treatment. The percutaneous drainage was performed for abscess decompression based on the preoperative ultrasound and CT scan. There is no complication was found and the patient was discharged on the twelfth day of hospitalization with optimal clinical improvement.
VLSI implementation of booth multiplier and carry select adder based fir filter design for ECG signal denoising

Over the last two decades, FIR filters have been the subject of intense research. The design of an adder, which is a major building component in circuit design, determines the overall performance of a system. The Finite Impulse Response (FIR) filter has been increasingly popular in signal processing applications in recent years. For signal processing field applications and VLSI systems, many adders are implemented. Signal denoising, as well as the production of an effective multiplier, had never been explained in any of the previous publications. This paper proposes 8 bit booth multipliers for partial products. The design employs the Carry select and Booth techniques. For partial product addition, the Carry Select Adder (CSA) is employed. The architecture of the FIR filter is proposed for operation with Electro Cardiogram (ECG) signal. It's known as CSA-BOOTH FIR, and it's used for denoising. Using the MATLAB application, the ECG signal with noise is sent into the filter. The denoising method is written in Verilog, with the output recorded in a text file. The binary values are read in MATLAB to denoise the signal. The performance of FPGAs and ASICs is evaluated.
Composition of Flavour Non Volatile Compound Steamed Snakehead Fish (Channa striata)

This research aims to identify the composition of non-volatile flavor compounds contained in steamed snakehead fish (Channa striata). This research was conducted at the Fishery Product Processing Laboratory, Faculty of Fisheries and Marine Sciences, Padjadjaran University, Jatinangor; Integrated Laboratory of IPB. The study was conducted experimentally by treating samples of fresh snakehead fish and steamed snakehead fish (at a temperature of 100oC for ± 30 minutes). A simple product description test was carried out on samples which included appearance, meat, aroma, texture, and taste. Identification of non-volatile flavor compounds using High Performance Liquid Chromatography (HPLC). The results showed that the product description test of steamed snakehead fish has an external appearance that is almost the same as fresh snakehead fish, the skin peels easily and the eyes of the fish are cooked. The texture of the meat is easy to tear. The distinctive aroma of a specific type of snakehead fish. Steamed snakehead fish has a distinctive taste mixed with the sensation of mud. The non-volatile flavor compounds identified as many as 15 amino acid compounds in the steamed snakehead fish sample. The two umami amino acids are 3,40% glutamic acid and 2,23% aspartic acid. The four sweet amino acids are alanine 1,28%, threonine 1,00%, glycine 0,94% and serine 0,84%. Nine bitter amino acids are lysine 2,12%, leucine 1,76%, arginine 1,37%, valine 1,08%, isoleucine 1,08%, phenylalanine 0,95%, tyrosine 0,76%, methionine 0,66% and histidine 0,55%.
The Influence of the Cartographic Transformation of TLS Data on the Quality of the Automatic Registration

This paper discusses the issue of the influence of cartographic Terrestrial Laser Scanning (TLS) data conversion into feature-based automatic registration. Automatic registration of data is a multi-stage process, it is based on original software tools and consists of: (1) Conversion of data to the raster form, (2) register of TLS data in pairs in all possible combinations using the SURF (Speeded Up Robust Features) and FAST (Features from Accelerated Segment Test) algorithms, (3) the quality analysis of relative orientation of processed pairs, and (4) the final bundle adjustment. The following two problems, related to the influence of the spherical image, the orthoimage and the Mercator representation of the point cloud, are discussed: The correctness of the automatic tie points detection and distribution and the influence of the TLS position on the completeness of the registration process and the quality assessment. The majority of popular software applications use manually or semi-automatically determined corresponding points. However, the authors propose an original software tool to address the first issue, which automatically detects and matches corresponding points on each TLS raster representation, utilizing different algorithms (SURF and FAST). To address the second task, the authors present a series of analyses: The time of detection of characteristic points, the percentage of incorrectly detected points and adjusted characteristic points, the number of detected control and check points, the orientation accuracy of control and check points, and the distribution of control and check points. Selection of an appropriate method for the TLS point cloud conversion to the raster form and selection of an appropriate algorithm, considerably influence the completeness of the entire process, and the accuracy of data orientation. The results of the performed experiments show that fully automatic registration of the TLS point clouds in the raster forms is possible; however, it is not possible to propose one, universal form of the point cloud, because a priori knowledge concerning the scanner positions is required. If scanner stations are located close to one another in raster images or in spherical images, Mercator projections are recommended. In the case where fragments of the surface are measured under different angles from different distances and heights of the TLS, orthoimages are suggested.
Building an ontological modeling mechanism for virtual cities

Modeling of cities is certainly a challenge. Most of this complexity is caused by the significant number of variables, as well as the vast manifestation for their ranks. Diverse efforts have been conducted by different researchers, in order to achieve powerful representations. Some of these efforts are aimed at graphical representation, some others are aimed at functionality. Present effort is aimed at the scaffolding support for the representation and, eventually, functionality of virtual cities. Such infrastructure would support current and future efforts devoted to populating virtual cities with agents showing different behaviors and roles. These agents would be active and concrete elements in cities, such as pedestrians, cars or drivers, and some others would be dynamic synthetic-elements, such as traffic lights or drawbridges. These agents will populate the city model and manifest in future efforts from this research; current effort is mainly focused in the production of cities’ infrastructure. The generation and representation of a virtual city is, per se, a significant challenge. This paper focuses in such challenge.
Are the Aetiologies of Traumatic Injuries Changing in Nigeria? Evidence from the Emergency Department of a Referral Hospital in Southwest Nigeria

Background: Traumatic injuries are a serious public health problem. The burden of these injuries is increasing globally, and there is evidence that the pattern is changing. Objective: The study had two objectives. The first was to determine the aetiology and clinical spectrum of trauma in a teaching hospital. The second was to determine whether these have changed compared with previous reports from the region. Materials and Methods: Between September 2017 and August 2018, data from injured patients who presented consecutively to the accident and emergency department at the Federal Teaching Hospital Ido-Ekiti, Nigeria, were prospectively collected using a trauma data form and analysed. Results: Road traffic crashes (RTCs) caused 75.6% of the injuries, and motorcycle crashes accounted for more injuries than all the other major causes of injuries combined. Compared with previous studies from the same hospital, assault has risen to the second position, whereas falls have fallen to the third position as causes of traumatic injuries. The Injury Severity Scores (ISS) of the patients ranged from 1 to 75, with a mean score of 7.01. The mortality rate was 2.5%. Time to treatment: odds ratio (OR) = 3.25 (1.1–10.0), ISS: OR = 1.172 (1.07–1.28), age: OR = 1.097 (1.013–1.188), and systolic blood pressure: OR=1.07 (1.106–1.025) were the significant predictors of mortality. No patient was transported to the hospital in an ambulance. Conclusion: The pattern of trauma in the subregion is changing as the proportion secondary to RTCs and motorcycle crashes is higher than previously reported studies from the area. The implication of this finding for the prevention of RTCs is discussed.
The Polarization of Metre-Wave Solar Emission

Sources of the Type I storms are thought to lie on closed magnetic loop systems above bipolar sunspots. Usually one sunspot is stronger than the other in the bipolar magnetic structure, and accordingly only one radio source associated with the stronger sunspot is usually observed. Occasionally however a double radio source is observed in conjunction with the bipolar sunspots. In such a case the double radio source should be intrinsically bipolar, viz. the two components should emit opposite senses of circular polarization (in this paper we use the word polarity for simplicity).
Macroeconomics Indicator, Institutional Quality, and Public Private Partnership: A Case of Indonesia

Objective: This study aims to provide empirical evidence about the effect of macroeconomic conditions (inflation and GDP growth) and governance (control of corruption, stability politics, and voice and accountability) on private participation in PPP infrastructure projects in Indonesia as proxied by a total investment of PPP project. Design/Methods/Approach: This study uses secondary data with annual data for the period 2003 to 2019. The data sources are obtained from the World Bank Database (WGI, WDI, and PPI). Findings: The results show that inflation, GDP growth, and stability politic have no significant effect on the total investment of the PPP in Indonesia. Meanwhile, control of corruption has a significant positive effect on the total investment of PPP, and voice and accountability have a significant negative effect on the total investment of PPP projects in Indonesia. Originality: This study differs from previous research since variables such as inflation, GDP growth, political stability, corruption control, voice, and accountability have never been used in the Indonesian context. Practical/Policy implication (optional): These findings are likely to imply government to improve corruption control so that private participation in PPP projects increases and increasingly involves citizens' participation in PPP projects.
Identiﬁcation of a Domain within Peroxisome Proliferator-Activated Receptor (cid:2) Regulating Expression of a Group of Genes Containing Fibroblast Growth Factor 21 That Are Selectively Repressed by SIRT1 in Adipocytes (cid:1) †

Peroxisome proliferator-activated receptor (cid:1) (PPAR ) activity is regulated through association with ligands that include the thiazolidinedione class of antidiabetic drugs, as well as derivatives of polyunsaturated fatty acids. Induction of PPAR (cid:1) target gene expression involves ligand-dependent reconﬁguration of the ligand-binding domain (LBD), followed by recruitment of speciﬁc transcriptional coactivators. In this study, we have identiﬁed an amino acid (F372) within helix 7 of the LBD that is required for the response of PPAR (cid:1) to endogenous ligands. Additionally, the data show that this amino acid is also required for expression of a novel subset of adipocyte genes (group 2), including ﬁbroblast growth factor 21 (FGF21), and that the FGF21 gene is a direct target of PPAR (cid:1) . Expression of the group 2 genes is selectively repressed by the NAD-dependent deacetylase SIRT1 in mature 3T3-L1 adipocytes, since knockdown of SIRT1 through the constitutive expres- sion of a corresponding RNA interference enhances their expression without affecting the expression of classic adipogenic genes, such as adiponectin and FABP4/aP2. It appears that many of the group 2 genes repressed by SIRT1 in mature adipocytes correspond to the same set of genes that are selectively activated by treatment of fat cells with the PPAR (cid:1) ligand, troglitazone. These data support a role for helix 7 of the LBD of PPAR (cid:1) in regulating adipocyte function and suggest that inhibition of SIRT1 in adipocytes induces the same insulin- sensitizing action as PPAR (cid:1) ligands.
INDIAN CONFRONTATION TO ECOMMERCE

The eCommerce sector has seen unprecedented growth in 2014. The growth was driven by rapid technology adoption led by the increasing use of devices such as smart phones and tablets, and access to the internet through broadband, 3G, etc, which led to an increased online consumer base. Furthermore, favoured demographics and a growing internet user base helped aid this growth. In terms of highlights, the growth shown by home grown players such as Flipkart and Snapdeal and the huge investor interest around these companies displayed the immense potential of the market. With the entry of eCommerce behemoths such as Amazon and Alibaba, the competition is expected to further intensify. Both these international players come with deep pockets and the patience to drive the Indian eCommerce market. Also, their strong domain knowledge and best practices from their international experience give them an additional edge. Additionally, these companies have been part of markets where they have seen the eCommerce market evolve and are aware of the challenges and strategies to address issues thereof