Miracle-dz/UniFAR-FTUs huggingface dataset:
Development of Four Crop Based Cropping Pattern Mustard-Boro-T. Aus-T. Aman Against Fallow-Boro-Fallow-T. Aman Rice

— A trial was conducted at multi-location testing (MLT) site Ranigonj, Dinajpur and Ghoraghat, Dinajpur under On-Farn Research Division (OFRD) during 2015-16 and 2016-17 to develop an economically sustainable and profitable cropping patterns, viz. Mustard (var. BARI Sarisha-14)-Boro (var. BRRI dhan28)- T. Aus (var. BRRI dhan48)-T. Aman (var. BRRI dhan62) against the farmers existing pattern Fallow- Boro (var. BRRI dhan28)- T. Aman (var. Swarna)-Fallow. The experiment was carried out in RCB design with six dispersed replications. Over both locations two years average results showed that the highest rice equivalent yield 20.82 tha-1 was obtained from four crops pattern. The highest average gross return and gross margin of the four crops pattern were obtained Tk. 333160 ha-1 and Tk.146463 ha-1 which was 93.70% and 122.58% higher over farmers existing pattern. The mean marginal benefit cost ratio (MBCR) was found 2.03 which indicated the superiority of four crops pattern over the farmers existing pattern. Both locations two years result showed that Grain yield of inclusion T. Aus rice and mustard yield were satisfactory that indicates the superiority of the alternate pattern over the farmer’s practice. So, it could be grown one after another in a sequence in the farmers field of Dinajpur region in Bangladesh.
of the Angiotensin II AT 1 Receptor Are Not Involved in Ligand Binding but Participate in Signal Transduction

The role of the external third of helix VI of the angiotensin II (AII) AT 1 receptor for the interaction with its ligand and for the subsequent signal transduction was investigated by individually replacing residues 252–256 by Ala, and residues 259 or 261 by Tyr, and permanently transfecting the resulting mutants to Chinese hamster ovary (CHO) cells. Binding experiments showed no great changes in affinity of any of the mutants for AII, [Sar 1 ]-AII, or [Sar 1 , Leu 8 ]-AII, but the affinity for the nonpeptide antagonist DuP753 was significantly decreased. The inositol phosphate response to AII was re-markably decreased in mutants V254A, H256A, and F259Y. These results indicate that AT 1 residues Val 254 , His 256 , and Phe 259 are not involved in ligand binding but participate in signal transduction. Based in these results and in others from the liter-ature, it is suggested that, in addition to the His 256 imidazole ring, the Phe 259 aromatic ring interacts with the AII’s Phe 8 , thus contributing to the signal-triggering mechanism. (Molecular Endocrinology 12: 810–814, 1998)
SYT1 Gene-Wide Analysis on White Matter Microstructure in Adulthood ADHD

Renata Basso Cupertino University of Vermont Bruna Santos da Silva Universidade Federal do Rio Grande do Sul Jaqueline Bohrer Schuch Universidade Federal do Rio Grande do Sul Cibele Edom Bandeira Universidade Federal do Rio Grande do Sul Maria Eduarda Tavares Universidade Federal do Rio Grande do Sul Pamela Ferreira da Cunha Universidade Federal do Rio Grande do Sul Felipe Almeida Picon Universidade Federal do Rio Grande do Sul Eduardo Schneider Vitola Universidade Federal do Rio Grande do Sul Diego Luiz Rovaris Universidade de Sao Paulo Eugenio Horacio Grevet Universidade Federal do Rio Grande do Sul Claiton Henrique Dotto Bau (  claiton.bau@ufrgs.br ) Federal University of Rio Grande do Sul https://orcid.org/0000-0001-5644-3845
High prevalence and diversity of Bartonella in small mammals from the biodiverse Western Ghats

Bartonella species are recognized globally as emerging zoonotic pathogens. Small mammals such as rodents and shrews are implicated as major natural reservoirs for these micro-bial agents. Nevertheless, in several tropical countries, like India, the diversity of Bartonella in small mammals remain unexplored and limited information exists on the natural transmission cycles (reservoirs and vectors) of these bacteria. Using a multi-locus sequencing approach, we investigated the prevalence, haplotype diversity, and phylogenetic affinities of Bartonella in small mammals and their associated mites in a mixed-use landscape in the biodiverse Western Ghats in southern India. We sampled 141 individual small mammals belonging to eight species. Bartonella was detected in five of the eight species, including three previously unknown hosts. We observed high interspecies variability of Bartonella prevalence in the host community. However, the overall prevalence (52.5%) and haplotype diversity (0.9) was high for the individuals tested. Of the seven lineages of Bartonella identified in our samples, five lineages were phylogenetically related to putative zoonotic spe-cies– B . tribocorum , B . queenslandensis , and B . elizabethae . Haplotypes identified from mites were identical to those identified from their host species. This indicates that these Bartonella species may be zoonotic, but further work is necessary to confirm whether these are pathogenic and pose a threat to humans. Taken together, these results emphasize the presence of hitherto unexplored diversity of Bartonella in the most common, and synanthropic small mammals. Several lineages identified are phylogenetically related to zoonotic species known to cause infections in humans. We suggest that there is unexplored diversity of Bartonella in small mammals that reside in human-modified landscapes in India, demonstrating an urgent need for further investigation. By identifying the natural reservoirs of pathogens, their ecology, and their relationship and proximity to humans, we will be able to proactively survey for these under-detected bacterial infections and minimize the burden.
Influence of Contextual Variables: An Application to Agricultural Research Evaluation in Brazil

In a research institution it is important to identify which management practices have influence on the production efficiency. In this paper we assess the statistical significance of contextual variables type, size, financial resources acquisition, intensity of partnerships, processes improvements and management change. The analysis is carried out for the Brazilian Agricultural Research Corporation over the period 1999-2006. The statistical analysis uses a balanced dynamic panel data model. We conclude that only financial resources acquisition is statistically significant. The association with the production process is positive. We also found statistically significant the two lag inertial component of the ratio conditional FDH to unconditional FDH indicating a two year effort to improve efficiency.
Voice Control Human Assistance Robot

— In today’s world technology has made our lives easier and more enjoyable for the people. However, we all benefit from this emerging technology, certain groups of people need more help and support than others: elderly or disable people. For them, technology can make a way of having an almost normal life. So, we focused our attention on the concept of a personal assistant robot. This automaton is principally designed for this cluster of individuals as its main purpose is to supply help to Associate in Nursing aged or disabled persons. Personal robotic assistants help to reduce the manual efforts being put by humans in their day-to-day tasks. The purpose is to implement a voice-controlled system as an Intelligent Personal Assistant (IPA) that can perform numerous tasks or services for an individual. This golem is specially designed for this cluster of individuals as its main purpose is to supply help to associate senior or disabled person. The human voice command is given to the robotic assistant remotely, by using a voice module (it is like ears of the robot). The tasks are based on some features embedded in the Assistant. The automaton will perform different movements, turns, start/stop operations. The robot can also read and recognize characters like alphabets as well as numeric [5]. This enhances the capability of the robot to detect objects and relocate them from one place to another. The most important characteristic of the Assistant is to give the trending information that the user has asked for. The input query by the user can be news regarding weather, politics, etc .
SURVEY OF THE KNOWLEDGE, ATTITUDE AND PRACTICE OF SURGERY TRAINEES TO HIV-INFECTED PERSONS AND AIDS PATIENTS IN RIYADH, SAUDI ARABIA

: Background : In our Islamic societies in contrast to most regions of the world the epidemiology of human immunodeficiency virus (HIV) is low. Data from the Middle East and North Africa (MENA) region suggests increasing incidence among key populations (people who inject drugs, men who have sex with men, transgender persons, sex workers and prisoners) in the region. Accurate data collection has long been limited by social, cultural, and religious taboos. Understanding knowledge levels and attitudes toward HIV/AIDS is an important component to design adequate and culturally appropriate awareness and prevention programs. Objectives: This study set out to determine the knowledge, attitude and risk perception of Saudi surgery trainees to HIV infection and AIDS. Methods: cross-sectional survey was conducted among 500 surgery trainees in Riyadh hospitals. Data was collected using a pretested, Online-administrated 30-item questionnaire and was statistically analyzed using SPSS software version 20. Design: cross sectional design Setting: online survey Main Outcome Measures: Knowledge gaps and negative attitudes of the surgeon trainees toward people living with HIV/AIDS Results: Most of participants (60%) were males with mean age of 35 years. Also 60% were married. Almost all of our participants (90%) aren’t concerned with estimation the HIV prevalence in their area. More than three quarters (82%) of them said that needle stick injuries (NSI) could occur from 5 to 6 times per year. The majority of participants (84%) occasionally exposed to HIV positive blood. 80% of them occasionally operated on AIDS patients unknowingly. The majority (81%) had an idea of the CDC guidelines for universal precautions against blood borne pathogens. Conclusion: Knowledge gaps and negative attitudes of the surgeon trainees toward people living with HIV/AIDS have been identified and can be improved by medical training and social media awareness campaigns. Limitation: sample size and limited areas of Saudi arabia
Relation between anabolic androgenic steroid administration, aerobic physical training and glycogen supercompensation

Glycogen supercompensation is one of the adaptations induced by physical training. To potentiate this phenomenon, many athletes use supraphysiological doses of anabolic androgenic steroids (AAS). The purpose of this study was to evaluate the effects of nandrolo- ne and aerobic physical exercise in rats, on body weight, plasmatic triglycerides levels, blood glucose and glycogen content. Male Wistar rats were randomly divided into 4 groups: Sedentary + ve- hicle (SV), Trained + vehicle (TV), Sedentary + AAS (SAAS) and Trained + AAS (TAAS) (n = 7-14/group). They received i.m. injec- tions of nandrolone or vehicle for 9 weeks, and during the same period trained rats were submitted to aerobic exercise. Data were analyzed by two-way ANOVA and Tukey tests (p (SV: 0,2 ± 0,02 = SAAS: 0,21 ± 0,02 mg/100 mg)). Blood glucose and soleus glycogen reserves re- mained unaltered. The use of supraphysiological doses of nandrolo- ne did not potentiate any of the effects obtained in response to aerobic physical training.
Ewing sarcoma: A pictorial review of typical and atypical locations with reference to the updated 2020 WHO classification system

Ewing sarcoma (ES) is a small round cell sarcoma which usually occurs in the paediatric and young adult age groups. This pictorial review briefly discusses and presents the typical skeletal and extraskeletal locations which ES is encountered, including the metadiaphysis of long bones, pelvis, chest wall and paravertebral regions. Five cases of ES in atypical locations are then presented along with an observation of demographic differences between skeletal and extraskeletal ES. These cases include ES arising from the metatarsal, scapula, breast, intracranial soft tissue and the paranasal sinuses. Presenting symptoms, treatment approach and prognosis are highly variable depending on the location; and multimodal imaging is centrepiece in the management process. Management usually includes any combination of chemotherapy, radiotherapy and surgery. The WHO classification system was updated in 2020 to include some of the rare genetic subtypes of ES. One such case of the BCOR subtype is demonstrated in this review and occurs in an atypical location. Whether these subtypes have distinct radiological features or a propensity to occur in atypical locations is an area for further research.
Engaging Multidisciplinary Engineers in an Introduction to Programming Laboratory

Engineering students outside of computer science are required to take an introductory course in computer programming in one of several languages (MATLAB, C++, VB.net), including a laboratory component. This provides a unique challenge in engaging a group of multidisciplinary students with different programming backgrounds, especially since the lab is required by some engineering majors but optional for others. The lab had essentially turned into a recitation session with additional lecturing and reviews of homework solutions. Over the last several semesters the college has reevaluated how the lab can be useful to all disciplines, and this paper outlines the curriculum redesign to problem-based learning in a collaborative classroom. Students now work in a space designed for active learning for two periods each week, grouped in teams of six. Their goal is to solve programming challenges that range from programming fundamentals to image processing and manipulating experimental data, which stimulates the interest of all engineering disciplines. Example labs include solving programming interview questions, using image kernels to sharpen digital images, and developing a simple Microsoft Paint application. These challenges correspond to the latest lecture material, forcing students to actively work through the current learning objectives and keep pace with the course. Each lab session has the support of a faculty member and teaching assistants to guide discussions and provide just-in-time teaching. Student feedback and grades have shown students are meeting the desired learning objectives while also enjoying the challenging nature of the problems. Students with no prior programming experience have especially benefited from the new lab format with strong improvements in critical thinking, creativity, and problem solving skills.
FILTERED-DYNAMIC-INVERSION CONTROL FOR FIXED-WING UNMANNED AERIAL SYSTEMS

OF THESIS FILTERED-DYNAMIC-INVERSION CONTROL FOR FIXED-WING UNMANNED AERIAL SYSTEMS Instrumented umanned aerial vehicles represent a new way of measuring turbulence in the atmospheric boundary layer. However, autonomous measurements require control methods with disturbance-rejection and altitude command-following capabilities. Filtered dynamic inversion is a control method with desirable disturbance-rejection and command-following properties, and this controller requires limited model information. We implement filtered dynamic inversion as the pitch controller in an altitude-hold autopilot. We design and numerically simulate the continuous-time and discrete-time filtered-dynamic-inversion controllers with anti-windup on a nonlinear aircraft model. Finally, we present results from a flight experiment comparing the filtered-dynamic-inversion controller to a classical proportional-integral controller. The experimental results show that the filtered-dynamic-inversion controller performs better than a proportional-integral controller at certain values of the parameter.
Novel targets to overcome antiangiogenesis therapy resistance in glioblastoma multiforme: Systems biology approach and suggestion of therapy by galunisertib

Glioblastoma multiforme (GBM) is a tumor with high microvessel density. Antiangiogenesis therapy (AAT) resistance occurs due to the complex mechanisms involved in angiogenesis, with increased chances of recurrence. The vascular endothelial growth factor (VEGF) pathway is the main pathway of angiogenesis, and anti‐VEGF drugs have been ineffective in controlling it. New oncogenes in the VEGF signaling pathway may be new candidates for angiogenesis targeting. Oncogene candidates were chosen using gene expression profiles and databases. Then oncogenes were subjected to gene set enrichment analysis (GSEA) and survival analysis (SA). Molecular docking was conducted to evaluate the interaction of the oncogenes with galunisertib. NRAS, AKT1, and HSPB1 were the most effective oncogenes upregulating genes that play a role in GBM expression in the VEGF signaling pathway. The VEGF and MAPK signaling pathways were found to be effective using GSEA and Kyoto Encyclopedia Gene and Genome pathway analysis. Survival analyses revealed that patients with high HSPB1 expression had poorer overall survival rates than those with low HSPB1 expression. Galunisertib exhibits intermolecular interactions with 6DV5, 5UHV, and 3O96 (binding energy −8.0, −8.6, and −10.3 kcal/mol, respectively). The current AAT should be restrategized to suppress the numerous angiogenic elements to manage angiogenesis and combat AAT resistance in GBM. In silico analysis indicated that NRAS, AKT1, and HSPB1 genes can be the main oncogenes in the VEGF signaling pathway and galunisertib strongly interacts with these genes. Consequently, the use of galunisertib to overcome AAT in GBM in combination therapy can be assessed.
Impact of surgical approach for left ventricular assist device implantation on postoperative invasive hemodynamics and right ventricular failure

Right ventricular failure (RVF) remains one of the major causes of morbidity and mortality after left ventricular assist device (LVAD) implantation. We sought to compare immediate postoperative invasive hemodynamics and the risk of RVF following two different surgical approaches: less invasive surgery (LIS) versus full sternotomy (FS).
Landscape Ecology in Riparian Buffer Zone Nuwas Buffer Zone in Baghdad as a Case Study

The buffer zone is an active component of the riverbank. It is the boundary between the bank and the river. Any damage that occurs in the buffer zone causes a number of problems in its natural and ecological structure. Most of these problems are diagnosable and observed in the outer space of the buffer zone. The appearance of these problems is in varying proportions depending on the type of human intervention in them. This intervention can have a negative effect on the riverbank on the one hand and on the river on the other. In light of this, studies have been directed towards examining various ecological mechanisms that ensure the safety of dealing with outer spaces in river buffer areas. The main research problem is represented in the lack of ecological value of the buffer zone in Abu Nuwas area in Baghdad City, as well as the lack of urban and design treatments causing a huge challenge of integration between the river and the city. In addition, the lack of connectivity with the buffer zone, which is a basic component connecting the water to the land. Moreover, few studies have dealt with this topic in studying the strategies of the landscape ecology of in the river buffer zone of Baghdad City. Thus, the research objective is to determine the mechanisms and indicators of the ecology of outer space, and apply them at the edge of the Tigris River (as a case study). Represented by Abu Nuwas area and park in Baghdad City, with the aim of further diagnosis of the situation of the buffer zone and the extent to which ecological values are applied. The results of the research in both its theoretical and practical aspects have produced a clear approach to ecological strategies that achieve buffer zone ecology and the development of specific mechanisms to provide a safe and effective river environment that accommodates various events and uses in the buffer zone, and enhance public awareness of its importance.
GROWTH FACTOR EXPANDED-GLIAL RESTRICTED PRECURSOR CELLS: SUPPORT OF NEURONS BY DERIVED ASTROCYTES by

Growth factor expanded precursor cells may be useful for therapeutic strategies in central nervous system tissue repair and regeneration. The ability to maintain precursor cells in a state of self-renewal allows for the production of large numbers of cells. The use of glial-restricted precursor cells (GRP) is therefore of great interest in the use of derived astrocytes for reparative strategies, such as on synthetic devices for guiding nerve growth. GRP cells could be a critical improvement because of the decrease in neuron supporting properties that differentiated astrocytes display with time in culture. In accordance to what has been observed for differentiated cells, precursor cells may also continue to measure elapsed time despite their state of self-renewal. It has not been addressed whether these internal timing mechanisms result in altered properties of the derived cells. This study investigated the changes in neurite outgrowth and cell adhesive properties of astrocytes derived from growth factor expanded GRP cells over various periods of time in culture. Astrocyte differentiation was induced after GRP cells were expanded in culture for up to seven weeks. Cerebellar granule neuron adhesion and neurite outgrowth were measured on monolayers of GRP-derived astrocytes at weekly intervals. Extended self-renewal of GRP cells in culture did not pause the functional changes associated with astrocyte maturation and astrocytes derived from expanded progenitors increased their surface area in correspondence with the length of time in culture. In addition to the flattened morphologies, prolonged proliferation also resulted in decreased chondroitin sulfate proteoglycan expression. These changes in astrocyte morphology and proteoglycan expression correlated with decreased neurite outgrowth and cell adhesion, and may correspond to the capability of GRP cells to intrinsically time the progress of development despite their state of self-renewal. An important implication of these findings is the insight that growth factor expansion of precursor cells in culture resulted in cells with a progressive decrease in neuron supporting properties.
EFFECT OF SOME SEAWEED EXTRACTS ON GROWTH AND SOME METABOLIC ACTIVITIES OF VIGNA UNGUICULATA PLANTS

: The present study aimed to investigate the effect of four seaweeds ( Sargassum crassifolia , , Enteromorpha flexuosa and Ulva lactuca ) water extracts on germination percentages, fresh and dry weights, leaf area, leaf area ratio (LAR), net assimilation rate (NAR), photosynthetic pigments, carbohydrate, and protein of Vigna unguiculata . Vigna seeds were pre-soaked for 6 hours in different extract concentrations (0, 5, 10, 40, and 80%) of the seaweeds, and then germinated in 0%, 10% and 20% of the different extracts. Presoaking of the plant seeds in low concentration of seaweeds extract (5%) has promoted their germination especially those extracts of Acanthophera najadiformis and Enteromorpha flexuosa which caused the greatest germination percentage. The maximum values of shoot and root length were obtained by the seeds pre-soaking in 5% or 10% of the different seaweeds extract s. Leaf areas, leaf area ratio (LAR), relative growth rate (RGR) and net assimilation rate (NAR) were increased in response to treatment the seeds with seaweeds extract which reflects the improvement of the plant growth. Chlorophyll a, b and carotenoids contents were also increased in response to treatment the seeds with seaweeds extracts. showed marked increases by the seeds pre-soaking in the seaweeds extract. Seeds pre-soaking in the seaweed extracts for a definite time were more effective compared to seeds germination in a medium containing the extracts.