Miracle-dz/UniFAR-FTUs huggingface dataset:
Unsupervised Machine Learning Identified Distinct Population Clusters Based on Symptoms of Oral Pain, Psychological Distress, and Sleep Problems

Objectives: The aims of this study were to explore the use of unsupervised machine learning in clustering the population based on reports of oral pain, psychological distress, and sleep problems and to compare demographic and socio-economic characteristics as well as levels of functional domains (work, social, and leisure) between clusters. Materials and Methods: In this cross-sectional study, a total of 1613 participants from the National Health and Nutrition Examination Survey in 2017–2018 were analyzed. Five variables, including oral pain, depression, anxiety, sleep apnea, and excessive daytime sleepiness, were selected for cluster analysis using the k-medoids clustering algorithm. The distribution of categorical variables between clusters was assessed using χ2 test. One-way analysis of variance and Kruskal–Wallis H test were used to compare numerical variables as appropriate. Results: Five distinct clusters were identified: healthy, norm, anxiety, apnea-comorbid, and pain-comorbid. The apnea-comorbid cluster had mean age of 59 years and higher proportion of men. The pain-comorbid cluster had mean age of 56 years and higher proportion of women. Whites constituted a majority of both comorbid clusters. The pain-comorbid cluster demonstrated the least percentage of individuals with college degree, the lowest income, and significant impairment in all functional domains. Conclusion: Through the use of unsupervised machine learning, the clusters with comorbidity of oral pain, psychological distress, and sleep problems have emerged. Major characteristics of the comorbid clusters included mean age below 60 years, White, and low levels of education and income. Functional domains were significantly impaired. The comorbid clusters thus call for public health intervention.
Evaluation of Dermoscopic Patterns of Vesiculobullous Disorders

Background: Clinical diagnosis of vesiculobullous disorders (VBD) is not always straightforward. It is a challenge for a dermatologist to make the right diagnosis noninvasively in a short time. Objective: To evaluate dermoscopic patterns associated with vesiculobullous disorders. Methods: A total of 230 patients, irrespective of age and gender, with a history and clinical presentation suggestive of VBD (including primarily infectious, inflammatory, genetic, antibody-mediated, mechanical, environmental, metabolic, and drug-related) were recruited into the study. Patients with secondarily infected lesions were excluded. Dermoscopic examination along with Tzanck smear/skin biopsy smear test was performed on the most representative lesions. Data were compiled and statistically analyzed using SPSS version 21.0. Results: Lesions with erythematous (vascular) and yellowish (serum) translucent background with regular margins were seen in most of the VBD studied. Chickenpox (CP) and herpes zoster (HZ) lesions evolved with the progress of their clinical stages. Follicular and eccrine openings were commonly seen, but the pigmentation around them was specific to pemphigus vulgaris. A distorted pigment network was noted in bullous pemphigoid. White rosettes (keratin blockage) were characteristic of epidermolysis bullosa, Wickham striae (orthokeratosis) of lichen planus, and crumpled fabric appearance (flaccidity) of Hailey-Hailey disease. Globules/dots (microvesicles) of different colors were also seen in various VBD. Blue/black color usually corresponded to retained melanin. Conclusion: Some dermoscopic patterns are observed consistently with certain diseases, and these can be used for their diagnosis, complementary to histopathological examination.
Effect of balanced anaesthesia with and without modified pectoralis nerve block on postoperative analgesia after breast surgeries: A randomised controlled trial

Background and Aims: Modified pectoral nerve block (PEC) has been reported to have variable effects on perioperative pain in patients undergoing surgery for carcinoma breast. This randomised controlled trial was conducted to study the effect of modified PEC on postoperative pain relief in patients undergoing breast surgery. Methods: Fifty patients with carcinoma breast undergoing breast surgery were randomised to receive a modified PEC block consisting of 30 ml of ropivacaine 0.2% after induction of anaesthesia (PEC group) or no block (GA group) in this prospective randomised trial. Time to first rescue analgesia was recorded as primary outcome. Other secondary outcomes recorded were postoperative visual analogue scale (VAS) scores, number of rescue boluses and 24-h fentanyl consumption. Results: There was no significant difference in time to first rescue analgesia between the two groups, with mean difference (95% confidence interval) of 22.91 (−6.8 to 52.69) min. Amount of fentanyl required to keep pain VAS less than 3 was also comparable between the two groups, mean (standard deviation) of 42.0 μg (17.42) in GA group versus 43.24 μg (17.22) in PEC group; P = 0.830.20/25 patients required rescue analgesia in GA group as compared to 17/25 in PEC group (P = 0.334). The postoperative VAS scores were also comparable between the groups at all time intervals. Conclusion: Balanced anaesthesia supplemented with modified PEC block performed after general anaesthesia did not improve the postoperative pain in patients undergoing modified radical mastectomy.
FeAsiBility analysis and development of on-Road chargIng solutions for future electric vehiCles

Executive Summary: The FABRIC project aimed to analyse the feasibility of dynamic wireless power transfer (DWPT) for electric vehicles at typical driving speeds. Two charging solutions (e-roads) were developed and demonstrated at the Susa test site in Italy. The first consisted of a series of 46 multi-windings coils and the second of a series of 22 simple single turn coils, all at a resonance frequency of 85 kHz. The coils were embedded at 6/7 cm deep and covered by asphalt. Both systems shared the same receiver installed on the testing vehicle. A third prototype based on the
High-Selectivity Bandpass Filter Based on Two Merged Ring Resonators

A high-selectivity bandpass filter (BPF) based on two merged ring resonators is presented in this paper. The structure of this proposed BPF can be seen as the two one-wavelength ring resonators merged each other by sharing the common λg/2 microstrip line. Due to symmetric structure, it can be analyzed by evenand odd-mode method and the locations of six transmission zeros are calculated using input impedance deductions. For further demonstration, a BPF example centered at 2 GHz is fabricated with high frequency selectivity. The measured 3-dB fractional bandwidth is 11% (1.89–2.11 GHz) and insertion loss is less than 2 dB in the passband. Good agreement between simulation and measurement verifies the feasibility of the design method.
Charity auctions from an economic perspective — literature review

One of the most common means of raising funds is the charity auction. At charity auctions, money is collected for a good cause, and the products are purchased for private consumption — the bidders may achieve both public and private gains. The charitable nature of this type of auction makes them different from standard auctions. The paper aims to present the main characteristics of this fundraising strategy as well as make a comparison with other formats of raising money for a good cause, i.a. lotteries. Furthermore, the main differences between charity and non-charity auctions will be explained. The studies do not clearly demonstrate whether the charity auction is a more effective mechanism of raising funds than the lottery. However, there is evidence that both formats outperform voluntary contributions. From the perspective of charity organizations, the most effective charity auction format seems to be the all-pay auction. The studies have also revealed that revenues at charity auctions are higher than at standard auctions.
Cul4a attenuates LPS-induced acute kidney injury via blocking NF-kB signaling pathway in sepsis

Background Acute kidney injury (AKI) is a common disease that can develop into end-stage kidney disease. Sepsis is one of the main causes of AKI. Currently, there is no satisfactory way to treat septic AKI. Therefore, we have shown the protective function of Cul4a in septic AKI and its molecular mechanism. Methods The cellular and animal models of septic AKI were established by using lipopolysaccharide (LPS). Western blot (WB) was employed to analyze Cul4a expression. RT-qPCR was employed to test the expression of Cul4a, SOD1, SOD2, GPX1, CAT, IL-6, TNF-a, Bcl-2, IL1b, Bax and KIM-1 mRNA. ELISA was performed to detect the contents of inflammatory factors and LDH. CCK-8 was utilized to detect cell viability. Flow cytometry was utilized to analyze the apoptosis. DHE-ROS kit was used to detect the content of ROS. Results Cul4a was down-regulated in cellular and animal models of septic AKI. Oxidative stress is obviously induced by LPS, as well as apoptosis and inflammation. However, these can be significantly inhibited by up-regulating Cul4a. Moreover, LPS induced the activation of the NF-kB pathway, which could also be inhibited by overexpression of Cul4a. Conclusions Cul4awas found to be a protective factor in septic AKI, which could inhibit LPS-induced oxidative stress, apoptosis and inflammation of HK-2 cells by inhibiting the NF-kB pathway.
Mapping Food Policy Groups

Over the past decades, there has been a rapid expansion in the number of Food Policy Groups (FPG) (including food policy councils, strategies, networks, and informal alliances) operating at municipal and regional levels across North America. FPGs are typically established with the intent of bringing together food systems stakeholders across private (e.g., small businesses, industry associations), public (e.g., government, public health, postsecondary institutions), and community (e.g., non-profits and charitable organizations) sectors to develop participatory governance mechanisms. Recognizing that food systems challenges are too often addressed in isolation, FPGs aim to instill integrated approaches to food related policy, programs, and planning. Despite growing interest, there is little quantitative or mixed methods research about the relationships that constitute FPGs or the degree to which they achieve cross-sectoral integration. Turning to Social Network Analysis (SNA) as an approach for understanding networked organizational relationships, we explore how SNA might contribute to a better understanding of FPGs. This paper presents results from a study of the Thunder Bay and Area Food Strategy (TBAFS), a FPG established in 2007 when an informal network of diverse organizations came together around shared goals of ensuring that municipal policy and governance supported healthy, equitable and sustainable food systems in the Thunder Bay region in Ontario, Canada. Drawing on data from a survey of TBAFS organizational members, we suggest that SNA can improve our understanding of the networks formed by FPGs and enhance their goals of cross-sectoral integration.
STUDENTS' PERCEPTIONS OF USING E-COMICS AS A MEDIA IN MATHEMATICS LEARNING

The development of technology in education greatly influences learning strategies. Thus, teachers must adapt and present interesting and technology-based learning, such as e-comics. Therefore, the teacher must see in advance the extent to which students will accept e-comics for use in learning mathematics. This research aimed to determine students' perceptions of the use of e-comics as a media in mathematics learning. This research implemented a quantitative approach with a survey method. The samples were 124 students of Junior High Schools (SMP / MTs) in Aceh. The research data were obtained from questionnaires filled by students which were collected through the TAM (Technology Acceptance Models) framework which was distributed online. The results showed that students used e-comic as a learning media influenced by their perceived benefits and attitudes towards the use of e-comic. The perceived benefits of students' attitudes have a significant role in their behavioral intention to use e-comic in learning mathematics. This research implies that e-comics has the potential to be used as a media in mathematics learning, especially on material that is considered difficult so that it can attract students' attention.
Employing Synthetic T-cell Biology to Target AML without On-Target/Off-Cancer Toxicity.

Ideal targets for chimeric antigen receptor T-cell therapy for acute myeloid leukemia (AML) remain elusive. In this issue of Blood Cancer Discovery, Richards and colleagues explore CD93 as a potential AML target antigen, and devise an approach to mitigate "on-target/off-cancer toxicity. "See related article by Richards et al., p. 648.
Pilot Study to Test Efficacy of Sira Vedha in Non-Alcoholic Fatty Liver Disease

Introduction: Sushruta said that the Sira Vedha (phlebotomy) at Dakshin Kurpara Sandhi (Right Elbow Joint) as a therapy for Yakrit Vikara (Liver Diseases). Modern science also on the same page that phlebotomy treatment for some liver diseases but did not mention the exact site for phlebotomy. Similarly, there is variation in the withdrawal of blood and time duration, every research study indicating different quantity to be withdrawn and the interval between two sessions. In the context of Ayurveda, both the things mentioned earlier are mentioned well in advance. Still, because of a lack of clinical evidence, one cannot confidently practice it in routine exercise. Thus, there is a need to validate Sushruta's principle with clinical evidence for liver diseases. Methodology: Twenty eligible patients who had Non-Alcoholic Fatty Liver Disease (NAFLD) Grade I/II were enrolled in the pilot study and randomly allotted for control (group A) and trial group (group B). Obtained written informed consent, each patient's blood serum was taken for aspartate transaminase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALK-P), and lipid profile. Then, group A patients were advised only diet alterations. Group B patients underwent diet alteration and Sira Vedha (phlebotomy) with 65 cc blood three times by the interval of 15 days. Before every phlebotomy, checked hemoglobin for safety purposes to discontinued the patient. The blood sample was taken before recruitment in the study and after the last follow-up, i.e., the 60th. Day—observation & Results: Compared the serum values of the first and final follow-up. Twenty patients (12 males and eight females) were enrolled, and the mean average age was 34.8 ± 7.84 years. This pilot study suggested that there was the improvement in liver enzymes and lipid profile significantly (P < 0.050) in group B compared to group A. Still, the changes that occurred with the treatment are not good enough to exclude the possibility that the difference was due to chance or because of small sample size. So, we can conclude that phlebotomy can improve liver enzymes and lipid profiles in patients with NAFLD.
Agronomic performance of forage sorghum and millet grown under irrigation with saline water and nitrogen doses in the Brazilian semi-arid

The saline and water stresses are part of the main factors that limit agricultural production. In semi-arid regions, these stresses are potentiated due to high rates of evapotranspiration and low precipitation. However, the supply of water and nutrients via fertilization can favor the maximization of crop production. In this sense, aimed to evaluate the agronomic and nutritional performance of sorghum and millet, submitted to different irrigation blades and increasing nitrogen doses. The research was conducted at Academic Unit of Serra Talhada-PE. The experimental design was a randomized block, arranged in subdivided plots, with four replications, arranged in the 4 x 4 factorial scheme, referring to 4 irrigation blades (28%, 36%, 44%, 52% ETc) and 4 nitrogen doses (0, 100, 200, 300 kg ha), adopting the Sorghum + Millet system, being sorghum the main crop. Seeding was carried out on April 7, 2017, with an average of 14 plants per linear. The irrigation blades were based on the ETc (ETc = ETo x Kc of sorghum). Nitrogen fertilization consisted of 1/3 in sowing and 2/3 in covering. Ended each cycle crop, plant height, stem diameter were measured, the number of live leaves was counted, green and dry mass yield was estimated, N-total, Na, K and Cl content were determined. Data were submitted to analysis of variance and variables adjusted to the regression model, using SAS Software. Nitrogen fertilization and irrigation with saline water benefited the growth of sorghum and millet crop. Nitrogen favors the absorption of N-total and potassium by plants and inhibited the absorption of chloride and sodium.
Associative Memory Using Random Vector Enhanced Phasor Neural Network

A new associative memory model composed of random vector enhancement followed by association is proposed. The Moore-Penrose pseudoinverse is employed to obtain the least-squares optimal solution; a gradient-descent type approach could also be used to obtain a near optimal solution. Computer simulations are performed to evaluate the model. Comparison of the proposed model with real domain backpropagation neural networks is presented. Simulations show that the proposed model can be trained orders of magnitude faster than real domain backpropagation neural networks.
Whole exome sequencing revealed a mutation in COL6A1 associated with ullrich congenital muscular dystrophy

Collagen type VI-related disorders consist of Ullrich congenital muscular dystrophies (UCMD) and Bethlem myopathy, in which these entities are at two opposite extremes of the phenotype continuum. Clinical characteristics include proximal joint contracture, distal joint hyperlaxity, generalized muscle weakness, normal cognitive function, and pulmonary insufficiency. Affected individuals have trouble standing up and walking independently. Mutations in 3 genes (COL6A1, COL6A2, and COL6A3) are associated with decreasing collagen-VI production and disrupting the microfibrillar network between skeletal muscles. In the present study, using whole-exome sequencing (WES), a pathogenic variant in the COL6A1 gene (NM_001848, c.868G>C, p.G290R) was detected in a Vietnamese family with UCMD patients. Segregation analysis by Sanger sequencing confirmed that this mutation was inherited in an autosomal dominant pattern. This study expands the breadth of congenital muscular dystrophies research landcape and underscores the efficiency of WES in investigating the etiology of this group of heterogeneous diseases. Insight about the underlying genetic causes could contribute to develop a well-timed treatment regimen and help patients make an informed decision about reproductive health.
Cross-diffusion waves resulting from multiscale, multiphysics instabilities: application to earthquakes

Abstract. Theoretical approaches to earthquake instabilities propose shear-dominated source mechanisms. Here we take a fresh look at the role of possible volumetric instabilities preceding a shear instability. We investigate the phenomena that may prepare earthquake instabilities using the coupling of thermo-hydro-mechano-chemical reaction–diffusion equations in a THMC diffusion matrix. We show that the off-diagonal cross-diffusivities can give rise to a new class of waves known as cross-diffusion or quasi-soliton waves. Their unique property is that for critical conditions cross-diffusion waves can funnel wave energy into a stationary wave focus from large to small scale. We show that the rich solution space of the reaction–cross-diffusion approach to earthquake instabilities can recover classical Turing instabilities (periodic in space instabilities), Hopf bifurcations (spring-slider-like earthquake models), and a new class of quasi-soliton waves. Only the quasi-soliton waves can lead to extreme focussing of the wave energy into short-wavelength instabilities of short duration. The equivalent extreme event in ocean waves and optical fibres leads to the appearance of “rogue waves” and high energy pulses of light in photonics. In the context of hydromechanical coupling, a rogue wave would appear as a sudden fluid pressure spike. This spike is likely to cause unstable slip on a pre-existing (near-critically stressed) fault acting as a trigger for the ultimate (shear) seismic moment release.
Modeling Vegetation with L-systems Using an Image

Realistic models of vegetations are very essential piece of immersive virtual environment simulations. We are developing a novel technique to render models of visually similar trees from a single reference image of a tree that is to be modelled. We use a user guided method to extract out the 2D skeleton. The technique also encompasses the usage of a procedural vegetation generation technique - the L-systems. In this report we present a modelling pipeline for developing a 3D tree model of tree starting from a single image of the tree.
Multi-Parameter Integrated Optical Sensor Based on Multimode Interference and Microring Resonator Structures

Current approaches to the real time analysis of chemical and biological sensing applications utilize systematic approaches such as mass spectrometry for detection. Such systems are expensive, heavy and cannot monolithically integrated in one single chip [1]. Electronic sensors use metallic probes which produces electro-magnetic noise, which can disturb the electro-magnetic field being measured. This can be avoided in the case of using integrated optical sensors. Integrated optical sensors are very attractive due to their advantages of high sensitivity and ultra-wide bandwidth, low detection limit, compactness and immunity to electromagnetic interference [2, 3].
FACTORS INFLUENCE ON CUSTOMER PURCHASE INTENTION VIA LIVETREAM: CASE OF VIETNAM

The main purpose of this study is to propose and empirically test a conceptual model that clarifies shopping behavior via livestream on Facebook platform of people in Hanoi. The data was collected from at least 240 random Facebook users. The analysis results show that Facebook users tend to buy goods via livestream when they feel that the product quality, design, and product policy are convincing enough for them. In addition, there are other factors that also influence purchasing decisions, such as technology quality, perceived value of style and attitude, reliability, product trust in the relationship between consumers and sellers such as livestream style, KOLs, sound & background… From there, theoretical and managerial contributions, as well as finding out limitations and future research directions are also discussed in the body of this paper Keywords: Shopping, Livestream, Livestream Products, Livestream People, Livestream Culture, Online Shopping.