Miracle-dz/UniFAR-FTUs huggingface dataset:
Pengaruh total quality management, dan budaya organisasi terhadap kinerja perusahaan

The purpose of this study was to determine the effect of total quality management, organizational culture on company performance. Quantitative research emphasizes the numerical assessment of the phenomena studied. Researchers used 2 (two) research approaches, namely descriptive research approach and exploratory research approach. The data used in this study is primary data. Data were obtained directly from informants who were selected purposively, while respondents were selected randomly (random sampling). The selection of respondents was based on the assumption that the population was relatively homogeneous. The results showed that there was a positive and significant relationship between organizational culture and total quality management and company performance. Likewise, the total quality management variable has a positive and significant effect on company performance. Meanwhile, organization culture has no positive and significant effect on company performance.
The Recent Developments of Molecular Dynamics Simulation

Based on the development of nanomaterials and the research on performance parameters of materials, molecular dynamics simulation has been rapid development and application. It is widely found that the material's physical, mechanical and other properties are both closely related to its macroscopic state and microstructure [. In order to explore and understand the nature of the material properties we need to analyze various impact factors including macroscopic, mesoscopic and microscopic. This paper describes the basic concepts and methods of molecular dynamics. The contents are comprised of time step, formulas such as Lagrange equations of motion and Hamiltonian equations of motion. The basic principles and recent developments of molecular dynamics were reviewed.
Effect of ghee residue on growth performance and economics of production of native chicken

The biological experiment was designed to study the effect of feeding ghee residue in native chicken (Aseel) for a period of 12 weeks on various parameters, viz. bi-weekly body weight, gain in body weight, feed consumption, feed conversion ratio, livability and the cost effectiveness of feeding ghee residue. A total of 300 day-old, unsexed, Aseel native chicken belonging to single hatch were utilized for this study. The treatment groups were fed with diets containing ghee residue at different inclusion levels, i.e. 0% (T1-control), 5% (T2), 10% (T3) and 15% (T4). Biological experiment revealed that there was significant difference in body weight and body weight gain and feed conversion ratio and no significant difference was observed in feed consumption and livability. The cost effectiveness of the native chicken fed with various levels of ghee residue showed increased net profit per kg live weight in the group fed 5% ghee residue.
Some exact solutions for Toda type lattice differential equations using the improved (G′/G)‐expansion method

Nonlinear lattice differential equations (also known as differential‐difference equations) appear in many applications. They can be thought of as hybrid systems for the inclusion of both discrete and continuous variables. On the basis of an improved version of the basic (G′/G)‐expansion method, we focus our attention towards some Toda type lattice differential systems for constructing further exact traveling wave solutions. Our method provides not only solitary and periodic wave profiles but also rational solutions with more arbitrary parameters. Copyright © 2012 John Wiley & Sons, Ltd.
Haematological and biochemical alterations in native sheep experimentally infected with bluetongue virus serotype-2

The study was designed to determine the haematological and biochemical alterations in sero-negative native sheep following the experimental bluetongue virus serotype-2 (BTV-2) infection. The BTV infected group comprised 14 sheep inoculated with 6 ml of clarified virus containing 1Ã—106/ml TCID50 of BTV-2 by intradermal route. The uninfected control group comprised 6 animals inoculated with 6 ml of cell culture medium without virus by intradermal route. The blood and serum samples were analyzed at 0, 1, 2, 3, 7, 11, 14, 21 and 45 days post-infection (dpi). Significant changes were observed in all the haematological and biochemical parameters studied. Marked leucopenia was observed from 2 to 7 dpi in BTV infected group. Significant leucocytosis was documented during 11 to 14 dpi in infected group. Significant thrombocytopenia was observed during 2 to 14 dpi whereas significantly low packed cell volume (PCV) and haemoglobin (Hb) values were observed between 3 and 21 dpi in BTV infected group. Differential leucocyte count revealed significantly low lymphocyte percentage on day 3 and high on day 11 in infected group. The various biochemical enzymes like alanine aminotransferase (ALT) showed significantlyhigh values during 3 to 21 dpi, aspartate aminotransferase (AST) during 3 to 21 dpi, alkaline phosphatise (ALP) during 3 to 11 dpi and creatine kinase (CK) during 7 to 14 dpi in BTV infected group. The result of our study demonstrated significantly decreased levels of total leucocyte count, total platelet count, haemoglobin and PCV values while significantly increased levels of ALT, AST, ALP and CK values in BTV infected group. On histopathological examination, spleen and lymph nodes showed depletion of lymphoid cells, liver and kidney showed degeneration, congestion and haemorrhage at many places. The BTV nucleic acid was detected from blood and tissues by RT-PCR. These findings indicated the damage to various soft tissue organs and muscles as a sequel to vascular endothelial damages caused by BTV.
Pendidikan Teman Sebaya melalui Pemberdayaan Kader Posyandu Remaja terhadap Pengetahuan, Sikap, dan Perilaku Remaja tentang Manfaat Gizi dalam Pencegahan Stunting: Penelitian Kuasi Eksperimen

Sebanyak 53 % remaja mengalami defisiensi energi berat dan 48 % defisiensi protein berat. Resiko lebih besar terjadi pada remaja putri, para calon ibu, di mana defisiensi gizi akan berdampak pada kesehatan ibu dan buah hati selama masa kehamilan dan melahirkan, seperti anak lahir dengan berat badan lahir rendah yang nantinya dapat menjadi stunting. Diperlukan suatu program pelayanan posyandu remaja untuk mencegah masalah stunting sedini mungkin. Penelitian ini bertujuan mengetahui pengaruh pemberdayaan Kader Posyandu Remaja terhadap pengetahuan sikap dan perilaku remaja tentang Gizi dalam pencegahan stunting di Kota Kendari. Jenis penelitian ini adalah kuasi eksperimen dengan desain one group pretest-posttest design yang dilaksanakan pada bulan Juli-November tahun 2021, dilakukan terhadap 45 kader posyandu dan 100 remaja peserta posyandu di wilayah kerja UPTD Puskesmas Puuwatu dan UPTD Puskesmas Abeli Kota Kendari. Sebelum pelatihan sebagian besar kader posyandu remaja tidak terampil setelah pelatihan sebagian besar kader posyandu terampil. Pengetahuan, sikap dan perilaku kader pada prates sebagian besar kurang, pada pascates sebagian besar menjadi baik. Remaja peserta posyandu sebagian besar memiliki pengetahuan, sikap dan perilaku kurang pada prates, setelah pendidikan teman sebaya aspek pengetahuan, sikap dan perilaku remaja tersebut sebagian besar menjadi baik. Secara statistik terdapat perbedaan yang signifikan pada sebelum dan setelah pelatihan dan pendidikan teman sebaya pada karakteristik penelitian. Diperlukannya pelaksanaan pelatihan secara berkala dan berkesinambungan.
Mobility and charge trapping comparison for crystalline and amorphous HfON and HfSiON gate dielectrics

Mobility and charge trapping results for n-channel transistors gated with HfON and HfSiON are reported as a function of physical thickness (Tphys). HfSiON peak mobility improves with Tphys over the range of 1.8–2.7nm, achieving 260cm2∕Vs at 2.7nm. However, HfSiON mobility degrades at a critical thickness, Tphys⩾3.5nm. HfON mobility response is different. It is a maximum (230cm2∕Vs) at Tphys=1.2nm but degrades with increasing thickness, particularly for the critical thickness ⩾2.5nm. Mobility loss and trapping occur concurrently for both dielectrics when these critical thicknesses are exceeded. These critical thicknesses are the minimum required to achieve dielectric crystallization. Interfacial defects along crystalline grain boundaries may negatively impact electrical performance of both dielectrics.
9th Immunotherapy of Cancer conference (ITOC): A meeting report

ABSTRACT The Immunotherapy of Cancer conference (ITOC) is an European meeting providing a global platform for discussions where all those dedicated to the immunotherapy of cancer can exchange their knowledge and the latest findings about immuno-oncology. The 9th ITOC was held in Munich in September 2022. Major highlights of the 2022 edition included the key note address and life time achievement to Laurence Zitvogel on her contributions on the understanding of the role of microbiota in cancer development and therapy resistance. Her research has paved the way for therapeutic exploitation of the microbiome.
Urban Identity Through the Prism of Media Framing

Urban identity is a complex phenomenon encompassing a wide range of city life aspects, which vary across cultures. In the media discourse, the urban issues are made prominent due to framing. The goal of the authors is to identify and systematize frames that generate meanings about the urban life, and explain them from the point of view of the journalistic strategies. The author focuses on exploring how topical urban issues are framed and presented to the reading audience. To gain a deeper understanding of the communicative schemata that determine interpretations of the city issues, a cognitive-discursive perspective is claimed central to the research. It proves adequate in demonstrating the synergies of two employed methods: discourse analysis and frame analysis. Applying a case-study approach, a sample of 658 texts is analyzed. 2577 contexts have been retrieved from The Nottingham Post between 2014 and 2017. The results show that the urban life representations rest on frame structures of different conceptual complexity. Urban identity is a rich conceptual structure (a macroframe), constituted by four frames, observable in the discourse-world of the city. Each of them has foci, which draw public attention to the social aspects of the urban living. Positive presentation of the authorities has been revealed as the leading macrostrategy aimed at supporting and approving of the initiatives taken by the local administration, which is realized through the strategies of reference, predication, and argumentation. The findings add to the framing analysis and could be beneficial for the development of urban policies.
Improved VO2max Estimation by Combining a Multiple Regression Model and Linear Extrapolation Method

Maximal oxygen consumption (VO2max) is an important health indicator that is often estimated using a multiple regression model (MRM) or linear extrapolation method (LEM) with the heart rate (HR) during a step test. Nonetheless, both methods have inherent problems. This study investigated a VO2max estimation method that mitigates the weaknesses of these two methods. A total of 128 adults completed anthropometric measurements, a physical activity questionnaire, a step test with HR measurements, and a VO2max treadmill test. The MRM included step-test HR, age, sex, body mass index, and questionnaire scores, whereas the LEM included step-test HR, predetermined constant VO2 values, and age-predicted maximal HR. Systematic differences between estimated and measured VO2max values were detected using Bland–Altman plots. The standard errors of the estimates of the MRM and LEM were 4.15 and 5.08 mL·kg−1·min−1, respectively. The range of 95% limits of agreement for the LEM was wider than that for the MRM. Fixed biases were not significant for both methods, and a significant proportional bias was observed only in the MRM. MRM bias was eliminated using the LEM application when the MRM-estimated VO2max was ≥45 mL·kg−1·min−1. In conclusion, substantial proportional bias in the MRM may be mitigated using the LEM within a limited range.
Management of Foreign Body Ingestion in Children: A Single-center Experience

Objective: Foreign body (FB) ingestion is frequently encountered in childhood, and although the clinical results are often benign, it has high morbidity and mortality rates. Although guidelines for managing these children are available, there are still controversial aspects of the treatment recommendations. This study aimed to evaluate the treatment options for children who swallow FBs. Methods: The study included 439 patients admitted with FB ingestion. Demographic and clinical features, type, size and localization of FB, treatment approach, and the timing of endoscopy were retrospectively scanned from hospital records. Results: Most patients were male (58.3%) and 69.7% of the patients were aged <5 years. The most common symptom (42.3%) was nausea and vomiting and 82.5% of the patients were asymptomatic. The most common localization was the intestines (59.7%). While 84.1% of swallowed FBs came out with a spontaneous passage without complications, the endoscopic removal procedure was successful at the rate of 91.8%. The most frequently swallowed FB was coins (39.6%). Spontaneous elimination rates were higher for small coins and endoscopic removal rates were higher for large coins (p<0.001). The rate of emergency endoscopy was significantly higher in cases who swallowed a 2.6 cm coin (p<0.001). It was found that all sharp/pointed objects located in the intestine on admission came out spontaneously without complications. Sharp/pointed objects and button batteries located in areas accessible by esophagogastroduodenoscopy were more frequently removed using the endoscopic technique (p<0.001). In the cases with the ingestion of a single magnet or superabsorbent FB (giant growing toys), the FB came out with spontaneous passage without any adverse clinical outcome. Conclusion: It can be suggested that this study of a large sample, showing the management of FBs without complications, will be of guidance in clarifying controversial aspects of the treatment.
Risk analysis of impacts of climate change on changes in municipal wastewater production in wastewater reuse plans

ABSTRACT Long-term changes in municipal wastewater production may disrupt wastewater reuse plans. However, no model/method has been developed to quantify the risks of climate change impacts on changes in wastewater production under relevant uncertainties. Accordingly, this research proposed a hybrid algorithm to analyze these risks under greenhouse gas concentration scenarios. This algorithm included a fuzzy risk assessment model based on six risk components and a framework for quantification of these components, which increased the relative confidence of decision-makers about risk values by 10%. The results showed that ‘considering’ and ‘ignoring’ the adaptive capacity to climate change under Representative Concentration Pathway scenarios in the risk analysis process lead to two completely different interpretations of risk. The risk difference based on these two approaches for Tehran was 50%, which was due to the occurrence of 11%–22% of untreated excess wastewater beyond capacity of wastewater reuse system under the temperature increase of 1.29°C.
Tunable refractive index materials with metallic nano-spheres dispersed in organic liquids

Metamaterials are of substantial current interest because they may exhibit unusual and/or configurable optical responses. We studied the optical properties of gold and silver nanoparticles dispersed in different organic liquids in the visible to near-IR. Calculation of the refractive indices of metallic nanospheres or metallic-coated silica spheres in liquid crystals show the possibility of tuning and varying the refractive index by reorientation of the liquid crystal molecules. Measurements of the refractive indices of gold nanoparticles in dodecane were experimentally studied by using spectroscopic ellipsometry and a reasonable agreement with the theoretical results based on Mie scattering was obtained. Finally, the effect of gold and silver nanospheres on the nonlinear absorption properties of an organic liquid (L34, a 4,4'-dialkyl phenyleneethynylene) was studied. The results suggest that metallic nanoparticles dispersed in a host organic fluids can be good materials for fabrication of low and tunable index materials in the visible to near-IR wavelength range, and for the enhancement of the nonlinear absorption of liquids used in switching applications.
Validation of Antidiabetic and Antihyperlipidemic Effects of 80% Methanolic Extract of the Lonchocarpus laxiflorus Leaves in Streptozotocin-Induced Diabetic Swiss Albino Mice

Introduction Diabetes mellitus (DM) is a chronic endocrine disorder that requires long-term treatment. In Ethiopian traditional medicine practice, plants have been provided with a vital role in fighting human and animal diseases since ancient times. The aqueous extract of Lonchocarpus laxiflorus (L. laxiflorus) leaves has been consumed for treating diabetes mellitus without confirming its safety and efficacy scientifically. This experiment aimed to evaluate the safety and antidiabetic efficacy of the leaf extract of L. laxiflorus in mice models. Methods The crude extraction was conducted using a cold maceration technique and 80% methanol solvent. Normoglycemic, oral glucose-loaded, and streptozotocin-induced (STZ) diabetic models were employed. Male Swiss albino mice were randomly grouped into five categories( with six mice per group during normoglycemic, oral glucose-loadingtest as a negative control, positive control, and three treatment groups. In STZ-induced diabetic models, the groups include normal and diabetic negative control, diabetic positive control, and three diabetic treatment groups. The negative control groups received vehicles, the positive control received 5 mg/kg glibenclamide, and the treatment groups received the crude extract at 100, 200, and 400 mg/kg doses, respectively. Results Up to 2000 mg/kg crude extract, neither signs of toxicity nor death were observed. In normoglycemic mice, there was a significant blood glucose reduction at 200 and 400 mg/kg doses starting from the 2nd h post-administration. The oral glucose load showed a significant antihyperglycemic effect at 200 and 400 mg/kg of the crude extract and glibenclamide. In STZ-induced diabetic models, the 200, 400 mg/kg crude extract, and glibenclamide showed a significant antidiabetic activity and enhancement of a good serum lipid profile. Conclusion This study confirmed that the leaf of L. laxiflorus was safe and possesses antidiabetic and antidyslipidemic activities.
600-V p-GaN Gate HEMT With Buried Hole Spreading Channel Demonstrating Immunity Against Buffer Trapping Effects

A 600-V p-GaN gate HEMT with buried hole spreading channel (BHSC) is demonstrated to suppress the buffer trap related dynamic <inline-formula> <tex-math notation="LaTeX">${R}_{\text {ON}}$ </tex-math></inline-formula> degradation. The BHSC is located at the interface between u-GaN and buried AlGaN. In the on-state, the holes injected from the p-GaN gate can effectively spread along the BHSC and screen the negative buffer charges. The hole spreading effect is verified by a detection of hole current from the sidewall of BHSC. The screening effect is verified by a positive substrate stress test that intentionally induces severe buffer trapping, which is widely known to cause severe dynamic <inline-formula> <tex-math notation="LaTeX">${R}_{\text {ON}}$ </tex-math></inline-formula> degradation in traditional GaN HEMTs. However, the propose device exhibits an immunity against buffer trapping owing to the screening effect of the holes along BHSC. The dynamic performance with as short as <inline-formula> <tex-math notation="LaTeX">$\sim 20~\mu \text{s}$ </tex-math></inline-formula> delay after a 400-V substrate stress is characterized. Nearly zero buffer trap related dynamic <inline-formula> <tex-math notation="LaTeX">${R}_{\text {ON}}$ </tex-math></inline-formula> degradation is achieved.
Coupling and Coordinating Relationship between Agricultural Eco-Efficiency and Food Security System in China

Carbon peaking, carbon neutrality goals and food security are the basis of sustainable development, and exploring the coordination relationship between China’s agricultural eco-efficiency and food security system has a major significance for the implementation of relevant strategies. This paper is based on collaboration research on the synergistic relationship between agricultural eco-efficiency and food security systems using methods such as entropy weight method, coupling coordination model, spatial autocorrelation model, etc., revealing the evolution-driven mechanism of the coupling coordination degree. This study found that a higher level of coupling coordination always occurs in those areas with high standard farmland construction and large grain production scale, while economically developed areas appear to have a lower overall coordination level limited by endowment constraints and division of labor in development planning. It shows a positive spatial correlation in terms of geographical distance between agricultural eco-efficiency and food security, and the positive spillover effect gradually increases but is not strong overall. China should combine regional resource endowment and development planning, pay attention to the improvement of large-scale and standardized agricultural production, continue to strengthen the development of clean agricultural production, and achieve food security under the constraints of the carbon peaking and carbon neutrality goals.
Sjögren’s syndrome: shedding light on emerging and key drug targets

ABSTRACT Introduction Sjögren’s syndrome (SS) is an immune-mediated inflammatory condition characterized by sicca syndrome, musculoskeletal pain, and fatigue. Extra-glandular manifestations are common and there is a markedly increased risk of lymphoma development. SS is associated with high health-economic burden driven largely by the symptom burden on patients. Currently, there is no approved disease-modifying treatment and management is based on empirical evidence. Progress in the understanding of SS pathogenesis has led to an expanding portfolio of more targeted therapies under development. Areas covered This review summarizes the key development in targeted biological therapies in SS including emerging targets. It also highlights the challenges in therapeutic development in SS such as disease heterogeneity and defining appropriate disease assessment tools to evaluate therapeutic efficacy. Expert opinion Early trials in SS failed to meet their primary outcomes which may in part due to the use of inappropriate or insensitive study endpoints. Recent trials targeting B-cells, B-T cell co-stimulation and IFN signaling have shown promising results. Development of composite endpoints including patient reported outcomes and objective disease measure may provide a more holistic approach to disease assessment. The impact of these new tools on therapeutic development that benefit patients remains to be fully evaluated.