Miracle-dz/UniFAR-FTUs huggingface dataset:
A Nascent Technique for Cultivated Feature Selection using Evolutionary Computation Algorithms

Evolutionary computation algorithms are in recent trends for feature selection due to their efficient results as compared to traditional algorithms. The performance of the evolutionary computational algorithm completely depends upon the parameter (like population, number of generations) setting. Existing parameter setting techniques have been developed for specific algorithms. This paper designs a generic pre-processing technique that removes the redundant as well as irrelevant features from the initial given feature set. This work uses Kendall tau to find the non-redundant feature and the Kruskal Wallis for the relevant features. If Kendall tau is not able to select any non-redundant feature then mutual information gain is used to select significant features followed by the Kruskal Wallis to select relevant features. The designed technique has been analyzed on 4 evolutionary computation algorithms, Modified Binary Particle Swarm Optimization, Non-dominated Sorting Genetic Algorithm, Binary Grey Wolf Optimization, and Binary Whale Optimization Algorithm over 6 datasets by using accuracy, the number of features in selected subset, sensitivity, and specificity. The present technique improves the performance of each algorithm in terms of accuracy, sensitivity, and specificity by 1 % on average with a 10 % reduction in the selected feature subset proves the significance of the proposed technique.
Effects of EGFR inhibitor AG 1478 on MDA-MB-231 and MCF-7 breast cancer cells

In this current study, antiproliferative effect of EGFR inhibitor AG1478 was investigated in human breast cancer cell lines. MDA-MB-231 and MCF-7 cell lines were used respectively as triple negative breast cancer and Luminal A breast cancer model. To this end cell viability, cell index values by xCELLigence Real‐Time Cell Analysis DP instrument and mitotic index analysis were used. The results of the current study showed that AG1478 had cytostatic effects on both of cell lines. The IC50 concentration was determined as 50 µM for MDA-MB-231 and 20 µM for MCF-7 cell line. IC50 concentration was used for mitotic index parameter. IC50 concentrations decreased the mitotic index values of both of cell lines. There were significant differences between the control and the experimental groups (p<0.05). The results of the present study suggest that AG1478 may serve as a promising treatment option for breast cancer.
Using Strategic Options Development and Analysis (SODA) to understand the simulation accessibility problem

Abstract Simulation modelling is applied to a wide range of problems, including defence and healthcare. However, there is a concern within the simulation community that there is a limited use and implementation of simulation studies in practice. This suggests that despite its benefits, simulation may not be reaching its potential in making a real-world impact. The main reason for this could be that simulation tools are not widely accessible in industry. In this paper, we investigate the issues that affect simulation modelling accessibility through a workshop with simulation practitioners. We use Strategic Options Development and Analysis (SODA), a problem-structuring approach that allows for the stakeholder views to be expressed and linked in a systematic way. The causal map derived represents the emerging concepts and their effects, with the view to identifying their impact on the accessibility problem. We present our analysis of the issues and options identified. Based on our findings, we discuss the implications and recommendations for the future uptake of simulation.
Efficient algorithms for subcircuit enumeration and classification for the module identification problem

The problem of extracting RTL modules from a gate level netlist has many interesting applications in digital design (V.K. Madiseti, 1999; P. Schaumont et al., 1999; K. Singh and P. Subrahmunyam, 1995), because it provides a conceptual description of the circuit. We approach this transformation by solving two subproblems: the identification of potential modules (candidate subcircuits) and testing them for functional equivalence to known high-level modules (subcircuit identification). We present a technique for unique and comprehensive enumeration of subgraphs of an arbitrary graph, as well as a method of recognizing subgraph isomorphisms. Combined, these results provide a solution to the problem of candidate subcircuit enumeration. These techniques provide both theoretical and practical contributions within design automation and graph theory.
2010 Rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative.

OBJECTIVE The 1987 American College of Rheumatology (ACR; formerly, the American Rheumatism Association) classification criteria for rheumatoid arthritis (RA) have been criticized for their lack of sensitivity in early disease. This work was undertaken to develop new classification criteria for RA. METHODS A joint working group from the ACR and the European League Against Rheumatism developed, in 3 phases, a new approach to classifying RA. The work focused on identifying, among patients newly presenting with undifferentiated inflammatory synovitis, factors that best discriminated between those who were and those who were not at high risk for persistent and/or erosive disease--this being the appropriate current paradigm underlying the disease construct "rheumatoid arthritis. " RESULTS In the new criteria set, classification as "definite RA" is based on the confirmed presence of synovitis in at least 1 joint, absence of an alternative diagnosis that better explains the synovitis, and achievement of a total score of 6 or greater (of a possible 10) from the individual scores in 4 domains: number and site of involved joints (score range 0-5), serologic abnormality (score range 0-3), elevated acute-phase response (score range 0-1), and symptom duration (2 levels; range 0-1). CONCLUSION This new classification system redefines the current paradigm of RA by focusing on features at earlier stages of disease that are associated with persistent and/or erosive disease, rather than defining the disease by its late-stage features. This will refocus attention on the important need for earlier diagnosis and institution of effective disease-suppressing therapy to prevent or minimize the occurrence of the undesirable sequelae that currently comprise the paradigm underlying the disease construct "rheumatoid arthritis. "
On A “Quantum” Proof Of The Equivalence of P And NP

We present an algorithm, along with a correctness proof, for solving the 3 Satisfiability problem that is inspired by quantum mechanical principles and that runs in polynomial time with respect to the size of the input problem. Even though we term both our algorithm and its associated proof as quantum (for reasons which we will demonstrate), it is intended to be run on standard classical computing (Turing complete) architecture. In the article, we posit that the 3 Satisfiability problem has an intrinsic complex quantum form that can be programmed in order to build a model of the solution space for satisfiable instances or show that such a model cannot be constructed. This yields surprising results on the ability for classical systems to abstractly simulate general quantum systems
Weapons in the Jungle of Femoro-Popliteal Lesions

Historically, Superficial Femoral Artery (SFA) lesions have been successfully treated using open surgical approach. A matter of debate has been about the best graft to be used: veins seem good options for below the knee district, synthetic graft should be used for above the knee region. However poor reported primary and assisted patency rates justify the need for a therapy with good procedural success, limited invasiveness and improved long-term outcomes. An increasing number of patients actually undergo endovascular treatment as a first line therapy for lesions in the femoro-popliteal district, for both intermittent claudication and critical limb ischemia. TASC II guidelines in fact showed that in short lesion (type A and B) endovascular treatment performs better than open surgery [1]. Abstention to surgery also could be an option in selected cases, with lifestyle education and exercise training program associated to medical treatment for claudicant patients. According to TASC guidelines [1], only Cilostazol and Pentoxifylline have been approved by FDA to improve walking distance in patients with intermittent claudication. Other proposed medical therapies, such as propionyl-L-carnitine, are still under investigation.
Combined Global Navigation Satellite Systems in the Space Service Volume

Besides providing position, navigation, and timing (PNT) services to traditional terrestrial and airborne users, GPS is also being increasingly used as a tool to enable precision orbit determination, precise time synchronization, real-time spacecraft navigation, and three-axis attitude control of Earth orbiting satellites. With additional Global Navigation Satellite System (GNSS) constellations being replenished and coming into service (GLONASS, Beidou, and Galileo), it will become possible to benefit from greater signal availability and robustness by using evolving multi-constellation receivers. The paper, "GPS in the Space Service Volume," presented at the ION GNSS 19th International Technical Meeting in 2006 (Ref. 1), defined the Space Service Volume, and analyzed the performance of GPS out to seventy thousand kilometers. This paper will report a similar analysis of the signal coverage of GPS in the space domain; however, the analyses will also consider signal coverage from each of the additional GNSS constellations noted earlier to specifically demonstrate the expected benefits to be derived from using GPS in conjunction with other foreign systems. The Space Service Volume is formally defined as the volume of space between three thousand kilometers altitude and geosynchronous altitude circa 36,000 km, as compared with the Terrestrial Service Volume between 3,000 km and the surface of the Earth. In the Terrestrial Service Volume, GNSS performance is the same as on or near the Earth's surface due to satellite vehicle availability and geometry similarities. The core GPS system has thereby established signal requirements for the Space Service Volume as part of technical Capability Development Documentation (CDD) that specifies system performance. Besides the technical discussion, we also present diplomatic efforts to extend the GPS Space Service Volume concept to other PNT service providers in an effort to assure that all space users will benefit from the enhanced interoperability of GNSS services in the space domain. A separate paper presented at the conference covers the individual GNSS performance parameters for respective Space Service Volumes.
MIGRATION IN KENYA : BEYOND HARRIS-TODARO 1

This paper examines the impact of agrarian structures on the migration behavior and destination of rural household heads and individuals in Kenya. To explore the complexity of migration we extend the standard Harris-Todaro framework to account for land inequality and size. In addition, we disaggregate urban destination into different types of urban centers and also consider rural-to-rural migration. Using logistic regressions, we show that Kenyan household heads born in districts with higher land inequality, smaller per capita land and lower per capita rural income are more likely to migrate. Hence, poverty and inequality in Kenyan rural districts are transmitted to other areas over time. Our estimates also show that, for peasants whose incomes are squeezed by larger land inequality, migration from villages to suburban Nairobi, smaller cities, and villages in different districts could be a preferable strategy to migrating to Metro Nairobi. The impact of land inequality is more significant for male migration than female migration. Moreover, the level of education, age, marital status, gender, religion and distance to Nairobi play a role in the migration behavior of rural dwellers.
Working Papers / Documents de travail

We examine the determinants of income inequality and mobility in a Ramsey model with elastic labor supply. Individuals differ both in their initial capital endowment and productive ability (labor endowment). With two sources of heterogeneity, initially poorer agents may catch up with the income and wealth of initial richer ones, implying that the Ramsey model is compatible with rich distributional dynamics. We show that the elasticity of the labor supply plays a key role in the extent of mobility in the economy. Capital-rich individuals supply less labor while ability-rich agents tend to work more. The more elastic the labor supply is, the stronger these effects tend to be and hence the greater the degree of income mobility is. JEL Classification Numbers: D31, O41
Integration of Power-To-Methane into Glass Melting Processes

The glass industry is facing increased challenges regarding climate protection targets and rising energy costs. The integration of renewable energy including conversion and storage is a key for both challenges in this energy-intensive industrial sector, which has been mainly relying on fossil gas so far. The options considered to this point for reducing CO 2 emissions and switching to a renewable energy supply involve far-reaching changes of the established melting processes. This entails signiﬁcant risks in terms of inﬂuences on glass quality and stable production volumes. The presented approach for the integration of a Power-to-Methane (PtM) system into the glass industry is a completely new conceptandhasnotbeenconsideredindetailbefore.Itallowstheuseofestablished oxyfuelmeltingprocesses,theintegrationofﬂuctuatingrenewableenergysources andasimultaneousreductionofCO 2 emissions by more than 78%. At the same time, natural gas purchases become obsolete. A techno-economic evaluation of the complete PtM process shows, that 1,76 e /m 3 or 1,26 e /kg synthetic natural gas are possible with renewable energy supply. Using electricity from the energy grid would require electricity prices < 0,126 e /kWh to allow cost competitive PtM processes in the glass industry. Such electricity prices could be achieved by electricity market-based optimization and operation of the PtM system. This operation strategy would require AI-based algorithms predicting availabilities and prices on future-based markets.
BERITA BIOLOGI

kangfajar@yahoo.com ABSTRACT Chromosome counting is the basis in describing the chromosomes number of organism that might useful for genetic study and classification. In banana studies, the root tip with a combination of non-fluorescent staining methods such as carmine or orcein and squash is the most common material for chromosome counting. In this study, we presented the usefulness of young anther of banana male bud with enzymatic maceration method for cell spreading and 4,6-diamino-2-phenyl-indole (DAPI) for staining agent to get a satisfying chromosomes image at metaphase for mitotic study of diploid and tetraploid bananas. The principle of this study is fixation using ethanol:acetic acid (3:1), enzymatic digestion, maceration and staining using DAPI. Our result showed that this method can provide well spread cells with intensely contrast of chromosomes images that satisfying for chromosome
Atypical manifestations of dengue fever in a recent dengue outbreak

Context: Dengue fever is highly prevalent in tropical and subtropical regions. The disease is caused by RNA virus, flavivirus and is transmitted by a mosquito to humans. Aims: The aim is to study the various atypical manifestations that can occur in dengue fever. Settings and Design: The patients presenting with acute febrile illness from September to December 2015 were admitted in a tertiary care hospital of North India and were screened for dengue fever. A total of 141 patients were screened for dengue fever out of which 61 patients were positive for dengue fever. A detailed history of each patient reporting to the hospital was taken followed by the general physical examination and systemic examination. Subjects and Methods: Complete blood count was performed in all patients and other investigations such as liver and kidney function test, chest X-ray, ultrasound, magnetic resonance imaging, and cerebrospinal fluid examination were done wherever required. Results: Atypical manifestations were present in 24 of 61 patients who were diagnosed positive for dengue fever (39.3%). Acalculous cholecystitis was the most common manifestation (32.7%), followed by encephalitis (6.5%) and hepatitis (3.2%). Transverse myelitis, acute respiratory distress syndrome, and renal failure had a frequency of 1.6%. There was no mortality as none of the patients had DSS in our study. Liver function tests (alkaline phosphatase and aspartate aminotransferase) were deranged in most patients (52.4%) out of which only 3.2% had raised serum bilirubin levels. Hepatomegaly was present in 19.6% of patients, and splenomegaly was observed in 3.2% of the patients. Conclusions: Dengue fever this year had various atypical manifestations – acalculous cholecystitis having the maximum occurrence. Neurological manifestations were also present. Transverse myelitis which is a rare manifestation was also observed.
Building adaptive capacity for flood proofing in urban areas through synergistic interventions

Few, if any urban areas are nowadays built in isolation from existing developments. Therefore, urban expansion and making existing urban areas more sustainable is a contemporary goal. There are major opportunities to do this through the ‘normal’ renewal of urban infrastructure and building stocks both now and in the future. However, significant building renewal cycles occur every 30-50 years and major infrastructure renewal cycles at even longer timescales of more than 100 years. Despite this there are significant opportunities to make buildings and infrastructure more resilient to external stress (an easier to realise goal than sustainability) beginning immediately. The challenge is to change the current norms for owners; urban planners; builders; professionals and policy makers to accept the need and urgency of doing this. Given the pace of climate and other changes and the need to manage carbon and energy better, there is an urgent need to begin to incorporate flexible, adaptable and more resilient measures by synergistic inclusion within refurbishment and renovation programmes. This needs to be recognised and planned as soon as possible, so that inclusion of such measures becomes the norm. Failure to do this will miss vital and unique opportunities that will hinder the delivery of carbon reduction targets. This is illustrated in the paper by recent studies in the Netherlands that have mapped urban flood and heat island vulnerabilities and identified where adaptive potential can best be targeted at the current building stock through refurbishment, renewal and regeneration and by reference to the latest developments in England and Wales.
A Framework for Developing Interactive Intelligent Systems in Unity

This paper introduces a lightweight framework for implementing intelligent interactive systems (IIS). In particular, systems that integrate symbolic knowledge bases for reasoning, planning and rational decision-making in interactions with humans. This is done by integrating Web Ontology Language (OWL)-based reasoning and Answer Set Programming (ASP)-based planning software. In order to provide interactive user components, the framework is encompassed in a widely used game development tool, Unity. The proposed framework, UnityIIS, is the first approach for integrating OWL together with ASP in Unity. Its central functionalities for knowledge representation and knowledge revision is presented together with an example application created in the framework. A chatbot agent, embodied in Augmented Reality, is designed, following a Belief, Desire, Intention (BDI) agent model. The set of tools that the framework provides can be applied for developing IIS research prototypes as well as being an asset in teaching practices.
SpanIE: A Span-based Approach to OpenIE

We introduce SpanIE, a span-based approach to solve the task of Open Information Extraction. SpanIE is a two-stage framework, providing a new way to leverage linguistic knowledge in proposition extraction from unstructured text. Our system recovers the underlying argument-predicate structure of a sentence from its dependency tree, and relies on the resulting sentence representation to solve the OpenIE task. The intermediate representation generated by SpanIE, is meant to benefit the information extraction process, allowing for accurate and expressive extractions. We conduct a preliminary comparative evaluation and present the experimental results to prove the effectiveness of the proposed approach. Using the benchmark framework for OIE, we show that our implementation achieves comparable performance with the state-of-the-art Open IE systems on the relation extraction task.
Improved Ni II oscillator strengths from quasar absorption systems

Aims. We wish to improve the accuracy of oscillator strength values for several Ni II UV transitions and measure for the first time the f-value of a few other weak transitions for which no laboratory nor astronomical measurement is presently available. Methods. Four quasars displaying five damped Lyman α systems with relatively strong Ni II lines were selected. From the analysis of the excellent high resolution spectra available, we determined the relative f-value of Ni II transitions by comparing the strength of the corresponding absorption profiles. To quantify the latter, we used the apparent optical depth method for resolved features, equivalent width measurements for optically thin lines and line fitting with VPFIT. Absolute f-values were then derived by relating our determinations to the available laboratory measurements. Results. Thanks to the good signal-to-noise ratio of the spectra and to the suitable properties of the absorption systems investigated, we are able to significantly improve the determination of the f-value for 13 Ni II transitions falling in the 1317–1804 Å interval. Our results are found to be consistent with other earlier determinations for ten of these transitions; our median relative accuracy for these f-values is 6.5%. For three weak transitions near 1502, 1773, and 1804 Å, which have not been detected previously in astronomical spectra, we can get a first measurement of their f-value. Conclusions. Our work illustrates that, thanks to the redshift and the absence of variations of physical constants on cosmological scales, the analysis of absorption lines induced by remote gas in quasar spectra can nowadays provide valuable constraints on atomic data in the UV range.
Review article on stem cell therapy

In this modern life, introduced to new diseases and disorders in which many organs and tissues get damaged. To treat this, stem cell therapy is one of the best treatment choices. A stem cell is an undifferentiated cell that can regenerate into any body tissue. This versatile nature of the stem cell made it possible to treat damaged tissues and organs. Stem cells are of two types embryonic and adult stem cells. An embryonic stem cell is pluripotent, and an adult stem cell is multipotent. Hematopoietic stem cell therapy is used to treat anaemia, and different types of cancer. Skin stem cell therapy treats chronic wound healing, chronic burns, etc.; neural stem cell therapy treats Alzheimer’s and Parkinsonism’s disease. Whereas mesenchymal stem cell therapy is used in the treatment of degenerative changes in the joint. This review article mainly discusses hematopoietic, skin, mesenchymal, and neural stem cell therapy.