Miracle-dz/UniFAR-FTUs huggingface dataset:
Simulations of Underground Storage of Natural Gas

The purpose of this thesis is to simulate fluid flows in aquifers used for natural gas storage. An introduction is given to aquifer flow modelling, and two models are developed that describe two-phase flow in porous media. The first model is constructed using the standard equations for Darcy flow and conservation of mass. The second model is then developed by integrating these equations in the vertical direction, and using the assumption of a sharp-interface and vertical equilibrium to evaluate the integrals. These two models were tested by running simulations on the aquifer model of Stenlille, a major gas storage facility in Denmark. The specifics of the aquifer model, such as the grid, fluid properties and so on, were based upon an existing ECLIPSE model. The goal was to improve the capability the simulations had in predicting pressures and water production rates for the wells in the aquifer. To this end, the ECLIPSE model of the aquifer was transferred into the MRST framework, where it was easier to experiment with the models themselves. The simulations run in MRST, using both the black-oil model and the VE model, were found to give successful predictions of the well pressures. As the VE model is two-dimensional, run-times were significantly lowered when this model was utilized. Neither the simulations run in MRST nor ECLIPSE were found to give successful predictions of water production rates.
Emerging Treatment Options for Acute Bacterial Skin and Skin Structure Infections and Bloodstream Infections Caused by Staphylococcus aureus: A Comprehensive Review of the Evidence

Abstract Staphylococcus aureus remains an important human pathogen of concern, with mortality rates surpassing 30% in the case of severe systemic infections. Distinguishing methicillin-susceptible S. aureus from methicillin-resistant S. aureus (MRSA) is fundamental for therapeutic choices. A crucial emerging concept in the treatment of acute bacterial skin and skin structure infections is the availability of various approved agents with anti-MRSA activity, which allow a personalized approach based on the characteristics of any given patient while at the same time remaining in line with high certainty efficacy evidence from large randomized controlled trials. Regarding the treatment of S. aureus bloodstream infections (BSI), interesting aspects that may become relevant in the near future are the presence of both old and novel agents in phase-2 or phase-3 of clinical development for this indication, and the pressing need for high certainty evidence to guide the possible use of combination therapy in specific categories or phenotypes of patients with complicated MRSA BSI.
Humic substances: effects on potato growth and yield

ABSTRACT The results from humic substances (HS) application in varied crops and conditions are controversial, and the experiments with the potato crop in Brazil are scarce. The objective of this study was to evaluate the effects of HS doses on the growth and yield of two potato cultivars. Four doses of HS were tested: 0, 5.05, 10.10, and 15.15 L ha-1, applied in the planting furrows of cvs. Agata and BRS F63 Camila, in Guarapuava-PR, in the 2015 and 2016 crop seasons, between October and February. The experiment was carried out using a randomized complete block design, in a factorial scheme (crop season x dose x cultivar), with four replications. Plant samplings were performed at tuber initiation, flowering, tuber bulking, and plant maturation growth stages. After shoot senescence, the total and commercial tuber yields were evaluated. Cultivars responded similarly to HS application, with no significant interaction between HS and cultivars, for most assessed variables. At tuber initiation, there was a negative linear effect of HS doses on leaf area index, number of formed tubers, and tuber and total plant dry weight. In the other evaluations, the effect of HS application was not observed regarding the assessed variables. Likewise, no effects were detected on the number and fresh weight of tubers in total and commercial yields. We concluded that HS application affected both cultivars similarly, hampering initial plant growth and not increasing potato yield.
Learning real manipulation tasks from virtual demonstrations using LSTM

— Robots assisting disabled or elderly people in activities of daily living must perform complex manipulation tasks. These tasks are dependent on the user's environment and preferences. Thus, learning from demonstration (LfD) is a promising choice that would allow the non-expert user to teach the robot different tasks. Unfortunately, learning general solutions from raw demonstrations requires a significant amount of data. Performing this number of physical demonstrations is unfeasible for a disabled user. In this paper we propose an approach where the user demonstrates the manipulation task in a virtual environment. The collected demonstrations are used to train an LSTM recurrent neural network that can act as the controller for the robot. We show that the controller learned from virtual demonstrations can be used to successfully perform the manipulation tasks on a physical robot.
Rethinking nonprofit service disintermediation through service communication interactions

PurposeA significant management issue for nonprofit organisations (NPOs) is the disconnect between services beneficiaries and the funders of those services. Individual donors and fundraisers provide the resources to enable other people (or animals) to be supported. The purpose of this paper is to address this service management challenge through new types of customer service interactions that bring together service donors and service recipients through innovative digital communication.Design/methodology/approachBased on a review, and illustrated by recent examples of innovative best practice, the authors develop a new conceptual framework for understanding the relationship between customer participation and service brand communication.FindingsThe paper starts by identifying the problem of “nonprofit service disintermediation”. The paper also outlines the inadequacies of popular frameworks of communication, widely taught in business schools, to understand the new reality of customer-service organisation engagement in the digital age. Through adopting a customer engagement lens, the paper develops a new conceptual framework for understanding the relationship between customer participation and service brand communication.Research limitations/implicationsGiven the authors’ focus on the intersection between new communication opportunities and customer service interactions, this paper adds novel insight to theory and raises important implications for management.Originality/valueThe paper explores how, through these new communication interactions, engagement with, and loyalty to, the brand is built over time in a fluid and dynamic way. It identifies a disintermediated relationship, distinct to other service contexts, but significant in terms of value and social impact.
Impact of process scaling on 1/f noise in advanced CMOS technologies

The influence of the gate-oxide thickness, the substrate dope, and the gate bias on the input-referred spectral 1/f noise density Sv/sub gate/ has been experimentally investigated. It is shown that the dependence on the oxide thickness and the gate bias can be described by the model of Hung, and that Sv/sub gate/ can be predicted for future technologies. Discrepancies with the ITRS roadmap are discussed.
Neovascular Remodeling and Subretinal Fibrosis as Biomarkers for Predicting Incomplete Response to Anti-VEGF Therapy in Neovascular Age-Related Macular Degeneration.

PURPOSE To compare the progression of neovascular remodeling and subretinal fibrosis in neovascular age-related macular degeneration (NVAMD) after anti-vascular endothelial growth factor (VEGF) therapy. METHODS Twenty eyes from 20 patients with subretinal fibrosis complicating NVAMD were retrospectively reviewed. All patients complied with at least three consecutive monthly intravitreal treatments and final follow-up visit at 12 months after the initial anti-VEGF treatment of aflibercept or ranibizumab. Using optical coherence tomography angiography (OCTA), the central macular thickness (CMT), microvascular density in the superficial capillary plexus (SCP), deep capillary plexus (DCP), choroidal neovascularization (CNV) lesions, as well as subretinal fibrotic lesions were compared between baseline and final visit. RESULTS The mean number for anti-VEGF injections was 4.40 ± 0.88 during the 12 months of follow-up. There was no significant difference in best-corrected visual acuity (BCVA) and vascular density in SCP and DCP (p > 0.05) between baseline and final follow-up. The CMT decreased from 434.95 ± 87.62 μm at baseline to 365.15 ± 78.92 μm at final visit (p = 0.02). Compared with the baseline, the fine vessels, such as capillary tufts, regressed and the relative density of CNV lesion decreased by 19.12% (p = 0.01), while the relative density of the subretinal fibrosis increased approximately 1.21-fold (p = 0.03) at the final follow-up. CONCLUSIONS The progression of neovascular remodeling and subretinal fibrosis may serve as biomarkers to predict incomplete response to anti-VEGF therapy in patients with NVAMD. Subretinal fibrosis complicating NVAMD remains a major obstacle for the management of NVAMD, and anti-VEGF treatment is a potential therapeutic strategy to target neovascular remodeling and subretinal fibrosis as either an additive or alternative therapeutic approach for NVAMD.
Targeted Therapy in the Management of Modern Craniopharyngiomas.

BACKGROUND The proximity of craniopharyngiomas (CPs) to critical neurovascular structures can lead to a host of neurologic and endocrine complications that lead to difficulty with surgical management. In this review, we examine the molecular and genetic markers implicated in CP, their involvement in tumorigenic pathways, and their impact on CP prognosis and treatment. METHODS We undertook a focused review of relevant articles, clinical trials, and molecular summaries regarding CP. RESULTS Genetic and immunological markers show variable expression in different types of CP. BRAF is implicated in tumorigenesis in papillary CP (pCP), whereas CTNNB1 and EGFR are often overexpressed in adamantinomatous CP (aCP) and VEGF is overexpressed in aCP and recurrent CP. Targeted treatment modalities inhibiting these pathways can shrink or halt progression of CP. In addition, EGFR inhibitors may sensitize tumors to radiation therapy. These drugs show promise in medical management and neoadjuvant therapy for CP. Immunotherapy, including anti-interleukin-6 (IL-6) drugs and interferon treatment, are also effective in managing tumor growth. Ongoing clinical trials in CP are limited but are testing BRAF/MET inhibitors and IL-6 monoclonal antibodies. CONCLUSIONS Genetic and immunological markers show variable expression in different subtypes of CP. Several current molecular treatments have shown some success in the management of this disease. Additional clinical trials and targeted therapies will be important to improve CP patient outcomes.
An efficient self-powered synchronous electric charge extraction interface circuit for piezoelectric energy harvesting systems

Harvesting ambient vibration energy using piezoelectric elements is a popular energy harvesting technique. Energy harvesting efficiency is the research focus. Using synchronous electric charge extraction technology in piezoelectric energy harvesting systems can greatly improve the energy harvesting efficiency. This article presents a self-powered efficient synchronous electric charge extraction circuit for piezoelectric energy harvesting systems, in which four self-powered switch circuits are used to optimize the time sequence of charge extraction so that the rectifier bridge circuit used in traditional synchronous electric charge extraction can be saved. The effect of phase lag on extraction efficiency, system energy, and loss of overall circuit is analyzed. A piezoelectric vibration experimental platform is built for testing the power generation performance of the self-powered efficient synchronous electric charge extraction and those published energy harvesting circuits. The experimental results accord with the theoretical analysis. Moreover, the harvesting energy of the proposed self-powered efficient synchronous electric charge extraction is about three times more than those of the standard energy harvesting circuit under its maximum power point and the self-powered synchronized switch harvesting on inductor in most cases. The energy harvesting efficiency of self-powered efficient synchronous electric charge extraction remains at a high level (>80%) in most cases, and the maximum energy harvesting efficiency is up to 85.1%.
Research on the Factors Related to Food Choices to Promote Healthy Eating

The problem of being overweight is becoming more and more serious, much attention has been paid to consumers’ food choices. A growing body of literature now demonstrates the importance of behavioral factors in individual food consumption. Understanding the psychology of how people make food choices that can lead to the cause of obesity, several insights from psychology and behavioral economics help explain why people are particularly vulnerable to the current food environment. In the article, we review the most important food consumption and behavioral economics and provide a thorough discussion of how such tools are now being added to change consumers’ behaviors. The paper discusses the improvement of the design of food policies, adjustment of the food label, framing of public health messages, carefully changing the consumers’ food choices so that people can change their choices.
Game, Set and Match: Secret Weapons of the World's Top Tennis Players

What better way to improve your tennis - and to gain a new appreciation for the sport - than by discovering the secrets of the world's greatest players and coaches? Read this book to improve your game with inside tips from the tennis elite, including those who have won Grand Slam titles and held the world number one ranking. Game, Set and Match is an unprecedented collection of tips from the sport's superstars, including Maria Sharapova, Andy Murray, Grigor Dimitrov, Venus and Serena Williams, Eugenie Bouchard, Kei Nishikori, Pete Sampras, Steffi Graf, Boris Becker, Stefan Edberg, Milos Raonic, Caroline Wozniacki, Stan Wawrinka, Jo-Wilfried Tsonga, Bob and Mike Bryan, Martina Navratilova, Gael Monfils, Petra Kvitova, Ana Ivanovic and Marin Cilic. There is also advice from Roger Federer's mother, Lynette on tennis parenting and tips from Rafa Nadal's uncle and coach, Toni, as well as other leading coaches such as Patrick Mouratoglou, Nick Bollettieri, Paul Annacone, Marian Vajda, Judy Murray, Darren Cahill, Roger Rasheed and Robert Lansdorp, and from fitness experts such as Andre Agassi's former trainer, Gil Reyes. Top tips from the pros include: 'How to disguise your serve' by Pete Sampras 'How to stay fit all year' by Caroline Wozniacki 'How to attack with your one-handed backhand' by Stan Wawrinka 'How to embrace your superstitions' by Goran Ivanisevic
Curved Path Following Control for a Small Fixed-Wing UAV with Parameters Adaptation

This paper presents an approach to address the curved-path following problem of a fixed-wing UAV, which can reach uniform optimal path-following performance for different initial states and control processes. First, a proper guidance law is designed following a class of horizontal smooth paths with fixed control parameters. The stability of the relative nonlinear system is guaranteed by the Lyapunov stability theory. The influence of the control parameters on path-following performance has been analyzed. Second, the rules of the time-varying control parameters are designed separately. The rules of the time-varying P-like parameter are designed by analyzing the dynamic characteristics of the nonlinear system with different initial flight states. The rules of the time-varying D-like parameter are designed based on the fuzzy logic technique. The stability of the corresponding nonautonomous nonlinear system is also proved. The simulations are carried out in the Matlab/Simulink environment with an Aerosonde UAV model. The results are presented to illustrate the effectiveness and high path-following performances of the proposed control strategies.
Prevalence and incidence of sarcopenia and low physical activity among community-dwelling older Thai people: a preliminary prospective cohort study 2-year follow-up

Background Sarcopenia, defined as a loss of muscle mass, has become a major health problem in older people. Few prospective studies report the incidence and risk of sarcopenia. Therefore, this study aimed to explore the prevalence of sarcopenia at the baseline and follow-up after 2 years in community-dwelling older Thai individuals. Methods In 2019, 330 older people were recruited from a community-dwelling population, and these participants were requested to present again in 2021. Sarcopenia was diagnosed using the criteria for the Asia Working Group for Sarcopenia (AWGS). All participants were asked to perform a 6-meter walk test, handgrip strength test, and bioelectric impedance assessment, and complete the Global Physical Activity Questionnaire. Results The study found that the prevalence of sarcopenia was 65 (19.70%) in 330 older people in 2019, and 44 of 205 participants (21.46%) were reported to have sarcopenia after 2 years. The incidence of sarcopenia was noted to be 2.44% in 2021. Analysis with ANOVA and pairwise comparisons showed that the reversibility of sarcopenia was attributed to high level of physical activity in the 2-year follow-up group (p = 0.014, 95% CI [−1753.25–−195.49]). Further, participants with moderate and high physical activity had a reduced incidence of sarcopenia (odds ratio = 9.00 and 14.47, respectively). Therefore, low physical activity in older people led to the development of sarcopenia from the baseline to the 2-year follow-up, indicating that increased physical activity may be useful in reversing sarcopenia, as suggested in the 2-year follow-up study. Low physical activity could be a risk factor for the incidence of sarcopenia. Hence, the prevention of sarcopenia could promote health improvement through moderate to high physical activity.
How synchronous participation affects the willingness to subscribe to social live streaming services: the role of co-Interactive behavior on Twitch

ABSTRACT Social computing has transformed the content industry. Content providers have changed from providing merely content to offering social content experiences that allow users not only to passively consume content but also to actively participate. As the latest development, social live streaming services (SLSS) have emerged that enable so-called co-interactive behaviour, i.e., the live interplay between users while co-experiencing content. Yet, it remains unclear how co-interactive behaviour affects the monetisation of social live content. Based on a data set of 868,940 users from 59 gaming channels of the freemium-based SLSS Twitch, we empirically show that co-interactive behaviour has a stronger effect on users’ willingness to subscribe (WTS) than passive and active behaviour. Since we find that a user’s reciprocated interactions also directly increase other users’ WTS, our results call for dismantling the current dichotomy of user participation and social influences in IS research. We suggest a social-experiential perspective that integrates social influences as an inherent part of users’ participation experiences. This novel interactive second-person perspective contributes to research on user engagement and value capture on social content platforms, and it allows SLSS providers to obtain a more precise picture of user value to better develop or adapt their monetisation strategies.
Episodic magmatism in the Dananhu arc, eastern Tianshan: Implications for the Late Palaeozoic tectonic evolution of the North Tianshan Ocean

ABSTRACT The North Tianshan Ocean represents a critical southwestern segment of the Paleo-Asian Ocean and is crucial for understanding accretionary and collisional processes of the southwestern Central Asian Orogenic Belt. The Dananhu arc belt, an important porphyry Cu deposit metallogenic belt in the eastern North Tianshan, records Paleozoic episodic magmatism. However, the tectonic affinity and evolution processes of the Dananhu arc belt are still open to debate. Here, geochronology, major and trace elements, and Sr-Nd-Hf isotope compositions for magmatic rocks are conducted to reveal the ages, petrogenesis, and tectonic settings of these magmatic rocks in the Dannanhu arc belt. The Carboniferous dacite (328 Ma) and gneissic granite (310 Ma) show high-K calc-alkaline, enriched in large ion lithophile elements (LILEs; e.g. Rb, Th, and U), depleted in high field strength elements (HFSEs; e.g. Nb, Ta, and Ti), depleted isotopic compositions (εNd(t) = 1.3-3.4; εHt(t) = 0.5-12.5) and juvenile Nd-Hf model ages. Combining these Carboniferous magmatic rocks with the features of high Sr-Ba granitoid and Sr-Nd isotopic decoupling, we suggest that these Carboniferous rocks were probably formed through fractional crystallization of partial melting of mantle wedge that had been metasomatized by melts from subducted sediments in a forearc setting. The early Permian granites (289-276 Ma) show high K2O+Na2O (6.9-8.9 wt.%), low MgO (0.06-0.15 wt.%) contents, high positive zircon εHt(t) (10.5 to 12.1) and whole-rock εNd(t) (4.4-5.5) values, suggesting that the early Permian granites were derived from juvenile lower crust in a post-collisional setting. Our geochronological and geochemical data, together with published data, reveal that high flux arc magmatism with age peaks at ca. 431 and 332 Ma is consistent with porphyry copper mineralization in the Dananhu arc belt, implying a close genetic relationship. The final closure of the North Tianshan Ocean was constrained to the late Carboniferous and early Permian. Graphic abstract
Central Peripheries: Nationhood in Central Asia

women and men more clearly would have helped bring forward the human, rather than group-based, dimension of the “Armenian issue. ” Thus, the perspectives of ordinary people get lost throughout the book. In this regard, Zabel Yesayan, an Armenian novelist, is worth mentioning in a detailed way because she was the only female intellectual targeted for arrest and deportation by the CUP. Centrally, the importance of political context that influenced the Turkish government’s approach is not clearly laid out throughout. While mentioning Turkish intellectuals’ anti-Armenian attitude, Cheterian refers to their support for Yaşar Kemal, a landmark name in Turkish literature, due to his comments criticizing state policies against the Kurds. According to the author, the same intellectuals were never interested in the “Armenian issue,” and so they were all distant (p. 137). This argument is ambiguous partly because Cheterian ignores the novelty of the “Armenian issue” for Turkish intellectuals. The final point is related to the editing of the book. Some Turkish words, including proper nouns, are misspelled and could be easily spotted by a native Turkish corrector. To conclude, Open Wounds shows how the past influences today through the critical aspects of the reception of the “Armenian issue. ” It is a valuable and insightful analysis that could be beneficial to the general audience and the experts of the topic. It also reveals what the literature needs: a complete, thorough, and well-rounded historical evaluation of intellectual debates about the issue because not only the factuality but also how this issue has been debated through time provides us the strategies to heal the bleeding wounds.