Miracle-dz/UniFAR-FTUs huggingface dataset:
Remote research methods for Human–AI–Robot Teaming

This study focuses on methodological adaptations and considerations for remote research on Human–AI–Robot Teaming (HART) amidst the COVID‐19 pandemic. Themes and effective remote research methods were explored. Central issues in remote research were identified, such as challenges in attending to participants' experiences, coordinating experimenter teams remotely, and protecting privacy and confidentiality. Instances of experimental design overcoming these challenges were identified in methods for recruitment and onboarding, training, team task scenarios, and measurement. Three case studies are presented in which interactive in‐person testbeds for HART were rapidly redesigned to function remotely. Although COVID‐19 may have temporarily constrained experimental design, future HART studies may adopt remote research methods to expand the research toolkit.
Dynamic Decision-Making Process of Evacuees during Post-Earthquake Evacuation near an Automatic Flap Barrier Gate System: A Broken Windows Perspective

The automatic flap barrier gate system (AFBGS) plays a critical role in building security, but it is more vulnerable to natural hazards than common exits (including power failure, due to earthquakes, and delayed evacuation, due to safety certification, etc.). This article considers a dynamic decision-making process of evacuees during post-earthquake evacuation near an AFBGS. An interesting metaphor, broken windows (BW), is utilized to interpret people’s actual behavior during evacuation. A multi-stage decision-making mechanism of evacuees is developed to characterize the instantaneous transition among three defined stages: Habitual, mild, and radical states. Then, we build a modified three-layer social force model to reproduce the interaction between evacuees based on an actual post-earthquake evacuation. The simulations reveal that BW provides a contextualized understanding of emergency evacuation with a similar effect to the traditional metaphor. An earlier appearance of a mild rule breaker leads to a higher crowd evacuation efficiency. If evacuees maintain the state of broken windows behavior (BWB), the crowd evacuation efficiency can be improved significantly. Contrary to the criminological interpretation, the overall effect of mild BWB is positive, but the radical BWB is encouraged under the command of guiders.
MICROBIAL SYNTHESIS OF SILVER NANOPARTICLES USING STREPTOMYCES SP. PG12 AND THEIR CHARACTERIZATION, ANTIMICROBIAL ACTIVITY AND CYTOTOXICITY ASSESSMENT AGAINST HUMAN LUNG (A549) AND BREAST (MCF-7) CANCER CELL LINES

Objective: Synthesis of silver nanoparticles using Streptomyces sp. PG12 and their characterization, antimicrobial activity and cytotoxicity against A549 and MCF-7 cancer cell lines. Methods: The silver nanoparticles were subjected to UV-Vis. spectroscopy, Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy with energy-dispersive X-ray spectroscopy (SEM/EDS), high-resolution transmission electron microscopy (HR-TEM), zeta potential, and X-ray diffractometry (XRD) analyses. Further, the antimicrobial potential was determined by using the agar well diffusion method and cytotoxicity was determined with the help of cell viability (MTT) assay and reactive oxygen species (ROS) assay. Results: The initial indication of silver nanoparticles synthesis was noticed by the colour change in the reaction mixture and the absorption maximum at 421 nm in UV-Vis. analysis; whereas, the FTIR analysis displayed the biological functional groups responsible for the capping and stabilization of silver nanoparticles. SEM and TEM micrographs revealed the surface morphology, spherical shape, and smallest particle size as 18.91 nm. The EDS and XRD patterns confirmed the involvement of various elements during the synthesis of silver nanoparticles and the crystalline, face-centered cubic nature, respectively. The silver nanoparticles displayed considerable antimicrobial activity against human pathogens even at low MIC and MBC concentrations and exhibited increased anticancer activity against A549 and MCF-7 cell lines, where the ability of silver nanoparticles to significantly restrict the growth of tumour cells was observed at IC50 values of 69. 04µg/ml and 138. 30µg/ml, respectively. Conclusion: Streptomyces sp. PG12 synthesized silver nanoparticles show significant anticancer activity against A549 and MCF-7 cell lines.
Sputum Cultures and Clinical Interpretation in the Management of Acute Pulmonary Attacks in a Child with Cystic Fibrosis

Questions: The interrelated questions are summarized as follows. And the answers are shared. 1) When the sputum culture were not available in a child with cystic fibrosis, would it be appropriate to take a throat culture in spite of sputum culture? 2) Is it appropriate not to begin the treatment until the sputum culture results available in an afebrile child with cystic fibrosis? 3) Is it necessary to take a control sputum culture during or at the end of the treatment? If it is yes, when should it be taken? 4) How should the treatment be managed if the sputum culture taken is resistant to the given treatment? (The questions came from different physicians) DOI: 10.5578/ced.202119822• J Pediatr Inf 2021;15(2):e119-e121 Clinical Clues / Klinik İpuçları
Analysis of Waste of Cost Factors During Engineering Phase of EPC Project with Lean Thinking (Case Study: PT.XYZ)

An engineering, procurement, and construction (EPC) company is challenged to compete in a cut-throat industry with many competitors and slim profit margin. Previous studies revealed that 70% of activities in a construction project are non-value adding which diminish productivity and profitability. As well as at PT. XYZ, the historical results showed that most of projects run by this company ended up in delay and cost overrun. Those previous studies had concluded that the most common factor that leads to project delay and cost overrun was poor design in engineering phase. This paper aims to identify the waste factors affecting cost during the engineering phase of EPC project at PT. XYZ. Lean information framework was utilized to identify and analyze the waste factors. Based on the extensive literature review, it was identified that there were 28 waste factors which can be classified into six groups of wastes. A questionnaire was designed and distributed to 48 participants to be filled out to investigate the dominant waste factors. The factor analysis, correlative test, descriptive and relative index analysis were then carried out. The results showed that the dominant waste factors are waiting for the needed documents, the long and far meetings, waiting for feedback information, waiting for the document approval, outdated information, and producing dummy document. The managerial implications are PT. XYZ should focus on efficient planning, streamlined information flow, pull-based planning activities, continuous improvement, and human resource development.
Phenylalanylphenylalanine as a Diagnostic Biomarker for Lung Cancer and Tuberculosis.

Background: Worldwide, lung cancer has the highest mortality rate, and pulmonary tuberculosis has a high incidence in China, and both may be misdiagnosed frequently because of similar clinical presentation and atypical imaging findings. Diagnostic biomarkers to distinguish between lung cancer and other pulmonary diseases can be detected by metabolomics to avoid non-essential treatment.Methods: This cohort study employed non-targeted and targeted metabolomic analysis in participants enrolled from three independent centers. Multivariate statistics, variable importance in the projection parameter, receiver operating characteristics (ROC) curve were used to build potential key diagnostic biomarkers model of lung cancer and these were subsequently analyzed using targeted metabolomics in test set. Quantitative analysis of differences in biomarker levels was conducted, and a support vector machine (SVM) classifier was used to identify the prediction rate of diagnostic biomarker model. Results: Phenylalanylphenylalanine showed opposite trends in lung cancer and tuberculosis. The area under the curve 0.8887 (95% CI 0.8064–0.9710, p<0.001, sensitivity 85.45%, specificity 84%), 0.8149 (95% CI 0.7419–0.8878, p<0.001, the sensitivity was 73.26%, the specificity was 78.43%) and SVM results (prediction rate 77.94%) showed the feasibility of using phenylalanylphenylalanine as a diagnostic marker for the differential diagnosis of lung cancer and tuberculosis.Conclusions: Changes in the levels of phenylalanylphenylalanine facilitate differential diagnosis between lung cancer and tuberculosis, thereby potentially reducing the damage caused by misdiagnosis in the clinical setting, and enabling early treatment of lung cancer patients.Trial registration: This study is registered in the China Clinical Trial Registration Center (registration number ChiCTR2000040666, Registered 07 December 2020, http://www.chictr.org.cn/index.aspx)
Recovery of sums of sparse and dense signals by incorporating graphical structure among predictors

With the abundance of high‐dimensional data, sparse regularization techniques are very popular in practice because of the built‐in sparsity of their corresponding estimators. However, the success of sparse methods heavily relies on the assumption of sparsity in the underlying model. For models where the sparsity assumption fails, the performance of these sparse methods can be unsatisfactory and misleading. In this article, we consider the perturbed linear model, where the signal is given by the sum of sparse and dense signals. We propose a new penalization‐based method, called Gava, to tackle this kind of signal by making use of a graphical structure among model predictors. The proposed Gava method covers several existing methods as special cases. Our numerical examples and theoretical studies demonstrate the effectiveness of the proposed Gava for estimation and prediction.
One-Pot Multicomponent Synthesis of 3-Methyl-4-(Hetero)Arylmethylene Isoxazole-5(4H)-Ones Using Guanidine Hydrochloride as the Catalyst under Aqueous Conditions

Abstract Here, we have developed an expeditious and efficient protocol for the synthesis of isoxazole-5(4H)-ones derivatives using guanidine hydrochloride as a catalyst using water as a solvent. The one-pot multicomponent reaction of aldehydes, ethyl acetoacetate, and hydroxylamine hydrochloride at room temperature to give a 3-methyl-4-(hetero)arylmethylene isoxazole-5(4H)-ones derivatives in an excellent yield. The key advantages of the reported method are shorter reaction time, energy-efficient, easy work-up procedure, wide substrate scope tolerance, economical, etc. further the catalyst was recycled up to 5 times along with high product yield without significant loss of its catalytic activity. Graphical Abstract
Aplicación de la metodología seis sigmas para mejorar la calidad de la estimación de densidad básica de la madera en Acacia mearnsii

La estimación de la densidad básica de la madera se realiza mediante el método tradicional regido por la Norma Tappi T 258 om-94, o bien, por la norma chilena NCh 176/2, las cuales son métodos destructivos, que demandan extensos tiempos, altos gastos en mano de obra y gran utilización de material. Buscando métodos que permitan reducir esos inconvenientes se testeó la metodología Seis Sigmas, utilizando el método DMAMC (Definir, Medir, Analizar, Mejorar y Controlar), para mejorar este proceso, y estimar este parámetro en tiempos y costos más reducidos. Para esto se probó la espectroscopía NIR (Near Infrarred) calibrada para predecir la densidad de la madera en Acacia mearnsii, utilizando polvo de astillado en estado seco obtenido de tarugos. El uso de esta tecnología fue apoyado con modelos estadísticos de regresión multivariantes de mínimos cuadrados parciales (PLS, Partial Least Squares), y se generó un modelo de calibración y un modelo de validación para el instrumento. El objetivo de este estudio fue mejorar los tiempos del cálculo de densidad básica, parámetro físico importante para la obtención de información de la biomasa, que se emplea como un estimador del material leñoso de una especie y del rendimiento que alcanzará en el pulpaje, así como para determinar la facilidad con la que esta se puede trabajar. Los niveles de predicción del modelo PLS fueron sobre el 80%, por lo que se valida el uso de la espectroscopía NIR como herramienta para predecir la densidad básica. Además, se aprecia un aumento en los indicadores de calidad, el nivel sigma aumentó de 0,18 a 3, el Cp de 0,26 a 1.08, el Cpk de 0,23 a 1 y los defectos por millón disminuyeron en un 99.6%. Además, utilizando la espectroscopía NIR disminuyen los costos en comparación con el método tradicional.
Rede dos conectores correlativos aditivos do português – uma abordagem diacrônica

Com base nos pressupostos teórico-metodológicos da Linguística Funcional Centrada no Uso (TRAUGOTT; TROUSDALE, 2013; FURTADO DA CUNHA; COSTA; CEZARIO, 2015; ROSÁRIO, OLIVEIRA, 2016), este trabalho tem como objetivo geral traçar as tendências de uso da construção correlata aditiva em língua portuguesa, do século XVI ao XXI. Objetiva-se também propor uma interpretação para a variação construcional atestada ao longo do tempo e, de uma forma mais ampla, contribuir para o desenvolvimento das pesquisas funcionalistas centradas no uso. Trata-se de uma pesquisa diacrônica de cunho qualiquantitativo que toma como base os trabalhos de Rosário (2012), Gervásio (2016) e Souza (2020), que constituem uma agenda comum de pesquisa em torno da correlação aditiva. A investigação baseia-se em diferentes corpora, especialmente formados de linguagem argumentativa. Os resultados evidenciam que a correlação aditiva, ao longo dos séculos, apresenta grande profusão de microconstruções em um real quadro de variação, ou seja, são aloconstruções (cf. CAPELLE, 2006; PEREK, 2015). Essas unidades simbólicas foram se formando ao longo do tempo por meio de mudanças pós-construcionais no campo da forma.
Flowers for cancer treatment: From beauty to duty

Cancer is a worldwide disease that affects millions of people every year. Although there are several approved chemotherapeutic drugs for cancer treatment, there is s constant search for new molecules. This search is supported by the need of new molecules that could target cancer cells specifically reducing side effects or that could act synergistically with approved anticancer drugs. In this review, research on flower extracts and flower-derived molecules is presented.
Effect of Sake Lees on the Inhibition of Lipid Accumulation in Adipocytes

Recent lifestyle changes, such as the Westernization of diets and the rise in the prevalence of obesity, with an associated increase in the number of patients with lifestyle-related diseases, have become a social issue. Fermented food has attracted attention as a solution to problems caused by obesity. Sake lees, a byproduct of sake brewing, represent one such food that is expected to have health benefits. In this study, we investigated the effects of sake lees components on preadipocytes (3T3-L1). We cultured preadipocytes in a medium with indigestible sake lees components (ISLCs) to investigate lipid accumulation, analyzed the glycerol 3-phosphate dehydrogenase (GPDH) and LPL activities of those cells, and performed a real-time PCR analysis of the IL6 expression in the cells. The results show that lipid accumulation and GPDH activity were significantly decreased in adipocytes treated with 1.0 mg/mL ISLCs compared to untreated cells. Furthermore, the expression of IL6 in adipocytes treated with 1.0 mg/mL ISLCs was significantly decreased and the lipase activity was significantly increased in adipocytes treated with ISLCs after differentiation. IL6 is known to have multiple functions in adipose tissue. In conclusion, ISLCs were associated with reduced lipid accumulation in adipocytes, with effects on IL6 expression and LPL activity observed throughout the differentiation period.
Effect of Ni-binder, PECS and MQL on face milling of Ti-6Al-4V

ABSTRACT The utilization of Ti-6Al-4 V for several engineering applications is usually not viable, due to the high cost associated with its machining. The poor thermal conductivity and high strain rate of Ti-6Al-4 V results in high concentration of stress at the cutting tool edge, leading to rapid tool degradation and subsequently poor surface integrity. This significantly affects the overall machining cost. Notwithstanding, the high hardness and toughness of WC-Co cemented carbide tools give them some leverage in Ti-6Al-4 V machining, but concerns over unstable prices, scarcity, toxicity and rapid degradation of cobalt have led investigations into alternate binder metals. This study investigates the effect of nickel as an alternate WC binder, pulsed electric current sintering (PECS) and minimum quantity lubrication (MQL) on mechanical properties and performance characteristics during face milling of Ti-6Al-4 V. The mechanical properties of the cutting tool inserts assessed were hardness and fracture toughness, while performance characteristics assessed were cutting forces, flank wear of the cutting tool inserts and surface roughness of the machined Ti-6Al-4 V surfaces.
Social Categorization Based on Language and Facial Recognition

Two experimental studies were conducted to replicate the effect found by Baus et al. where language as a marker of social categories affected recognition of faces in an old/new paradigm. In Study 1, we presented faces along with utterances in Swedish and in English to native Swedish speakers. Faces presented along with Swedish utterances were not recognized better than faces presented along with English utterances. In Study 2, we used another language pair and presented faces along with utterances in Swedish and in Spanish to native Swedish speakers. Faces presented along with Swedish utterances were recognized better than faces presented along with Spanish utterances. Our results suggest that language functions as a marker of social categories and that, similarly to other markers of social categories, it can be modulated by various factors and is not unconditional.
Infeção pelo Vírus da Imunodeficiência Humana: vivências e comportamentos de risco

Este artigo explora as vivencias e os comportamentos de risco de pessoas que vivem com a Infecao pelo Virus da Imunodeficiencia Humana. Analisa as manifestacoes dos comportamentos individuais, os seus significados, mas tambem os determinantes coletivos que influenciam quer as estrategias de prevencao, quer a sua ausencia. Evidencia, igualmente, a singularidade das vivencias das pessoas que vivem com a Infecao pelo Virus da Imunodeficiencia Humana na sua relacao com o genero, a escolaridade, o corpo, entre outras variaveis, mas tambem com comportamentos e atitudes que resultam em processos de discriminacao e estigmatizacao das pessoas infetadas. Para o efeito, foi mobilizada uma abordagem qualitativa, com o recurso a entrevistas semiestruturadas. Os resultados alcancados revelam que a vivencia da Infecao pelo Virus da Imunodeficiencia Humana varia nao so em funcao do genero, mas tambem decorre do maior ou menor capital escolar, economico e socioprofissional dos entrevistados, que os dota de recursos diferenciados na gestao da infecao
Análisis de latencia en modelo FANS para servicios IoT

El presente trabajo plantea la creación de un escenario real de operación de una red de fibra óptica conformada en base al estándar FANS (Fixed Access Network Sharing) de Broadband Forum, en la que se simule el manejo de un tráfico modelo correspondiente a dispositivos IoT. Para esto se propone la realización de distintas maquetas que representen el modo de funcionamiento de una arquitectura FANS manejando las condiciones de tráfico correspondientes, de forma que se puedan extraer conclusiones sobre la latencia, que es el parámetro de mayor importancia considerado por la industria en contextos de uso sobre redes 5G que se interconecten por medio de redes de fibra óptica. El objetivo del estudio es determinar si alguno de los modelos del estándar podría ofrecer ventajas ante escenarios de redes compuestas por dispositivos IoT que sean sensibles a la latencia.
Objetivos de intervención en voz: Una propuesta para su análisis y redacción

Este artículo de reflexión aborda aspectos que dan cuenta de la complejidad en el planteamiento de objetivos en torno a los marcos de abordaje vocal contemporáneos. Se plantea la complejidad de la selección y redacción de objetivos para la intervención en voz holística y ecléctica, y desde ella, la necesidad de incorporar el modelo CIF y las recomendaciones de la ASHA para el desarrollo de objetivos centrados en la persona, tanto a corto como a largo plazo. Se propone la utilización del método de análisis SMART y su aplicación específica para objetivos de intervención de la voz. Además, se abordan los aspectos formales que se deben considerar para una redacción precisa. Finalmente, se ejemplifica la propuesta mediante un caso clínico. Esta propuesta pretende ser de utilidad para fines terapéuticos y/o para el ámbito académico, tanto en la discusión de la formulación y diseño de planes terapéuticos como en el pensamiento reflexivo asociado al abordaje vocal.
Molecular and phylogenic identifications of potential herbicide degrading microorganisms from contaminated farmland in Keffi, Nasarawa State, Nigeria

Background: Over the past years, the continuous use of herbicides has raised increasing concern mainly due to their massive pollution of the environment. To address this problem, the herbicide-degrading microorganism might be very promising. Method: In the present study, a total of twenty (20) soil samples were collected, bacteria and fungi were isolated from the soil and identified using standard microbiological and molecular studies. Results: The results revealed that a total of 2 bacterial (Enterobacter asburiae and Pseudomonas aeruginosa) and 2 fungi (Aspergillus flavus and Fusarium redolens) strains were isolated from the soil samples collected from herbicide contaminated soil in Keffi, Nasarawa State, Nigeria. The E. asburiae and P. aeruginosa had 75.0%, and 100% occurrence while the fungi isolates including the A. flavus and F. redolens had 75.0%, and 100% occurrence respectively. The 16S rDNA and ITS1F analysis confirmed the identity of the bacteria and fungi genus. Phylogenetic analysis suggested the bacteria strains were closely related to Pseudomonas aeruginosa strain CIFRI DTSB1 and Enterobacter sp revealed a close relatedness with Enterobacter asburiae RD-DAROS-04 strain, whereas, the fungi strain revealed a closely relatedness of Fusarium redolens strainTIST190421511. Conclusion: In conclusion, the microbial strains including Pseudomonas aeruginosa strain CIFRI DTSB1, Entrobacter asburiae RD-DAROS-04, and Fusarium redolens strainTIST190421511 were the major microbial habitant of pesticide-contaminated farmland in Keffi, and thus represent the herbicide degrading microorganism in this region. Further studies on the herbicide degrading properties of these microbial strains are underway.