Miracle-dz/UniFAR-FTUs huggingface dataset:
THE BOLOCAM GALACTIC PLANE SURVEY. XIII. PHYSICAL PROPERTIES AND MASS FUNCTIONS OF DENSE MOLECULAR CLOUD STRUCTURES

We use the distance probability density function formalism of Ellsworth-Bowers et al. to derive physical properties for the collection of 1,710 Bolocam Galactic Plane Survey (BGPS) version 2 sources with well-constrained distance estimates. To account for Malmquist bias, we estimate that the present sample of BGPS sources is 90% complete above 400 M ☉ ? > and 50% complete above 70 M ☉ ? > . The mass distributions for the entire sample and astrophysically motivated subsets are generally fitted well by a lognormal function, with approximately power-law distributions at high mass. Power-law behavior emerges more clearly when the sample population is narrowed in heliocentric distance (power-law index &agr; = 2.0 ± 0.1 ? > for sources nearer than 6.5 kpc and &agr; = 1.9 ± 0.1 ? > for objects between 2 and 10 kpc). The high-mass power-law indices are generally 1.85 ≤ &agr; ≤ 2.05 ? > for various subsamples of sources, intermediate between that of giant molecular clouds and the stellar initial mass function. The fit to the entire sample yields a high-mass power-law &agr; ˆ = 1.94 − 0.10 + 0.34 ? > . Physical properties of BGPS sources are consistent with large molecular cloud clumps or small molecular clouds, but the fractal nature of the dense interstellar medium makes it difficult to map observational categories to the dominant physical processes driving the observed structure. The face-on map of the Galactic disk’s mass surface density based on BGPS dense molecular cloud structures reveals the high-mass star-forming regions W43, W49, and W51 to be prominent mass concentrations in the first quadrant. Furthermore, we present a 0.25 kpc resolution map of the dense gas mass fraction across the Galactic disk that peaks around 5%.
Direct Association of pllO3 Phosphatidylinositol 3-Kinase with p85 Is Mediated by an N-Terminal Fragment of pllO3

Phosphatidylinositol (PI) 3-kinase is a heterodimeric enzyme of 85-kDa (p85) and 11O-kDa (p110) subunits implicated in mitogenic signal transduction by virtue of its activation in cells transformed by diverse viral oncoproteins and treated with various growth factors. We have identified a domain in plO that mediates association with p85 in vitro and in intact cells. A glutathione S-transferase fusion protein containing the N-terminal.171 amino acids of pilOjl bound to free p85 in cell lysates. This fusion protein also bound directly to p85 immobilized on nitrocellulose filters. An epitope-tagged fragment containing amino acids 31 to 150 of pllO,B associated with p85 upon expression in intact cells. Expression of either an N-terminal fragment of pllOp or the p85 inter-SH2 domain, which mediates association with p110, reduced the association of endogenous PI 3-kinase activity with the activated platelet-derived growth factor receptor in intact cells. Hence, these defined regions of p85 and pllO mediate the interaction between the two subunits of PI 3-kinase. Phosphatidylinositol (PI) 3-kinase enzyme which the 3' OH of the inositol ring PI 3-kinase a of viral and
Directly to Specific Recognition Macrophage Transcription Is Coupled Cells: Repression of Proinflammatory Innate Immune Discrimination of Apoptotic

Physiological cell death is a process the purpose of which is the elimination of functionally inappropriate cells in a manner that does not elicit an inﬂammatory response. We have shown previously that the ability of apoptotic corpses to be recognized by macrophages and to modulate the proinﬂammatory responses of those cells represents paradoxically a gain-of-function acquired during the physiological cell death process. Cells that die pathologically (that is, necrotic vs apoptotic corpses) also are recognized by macrophages but do not down-regulate macrophage inﬂammatory responses; the recognition of these two classes of native dying cells occurs via distinct and noncompeting mechanisms. We have examined the apoptotic modulation of proinﬂammatory cytokine gene transcription in macrophages (by real-time RT-PCR analysis) and the corresponding modulation of transcriptional activators (by transcriptional reporter analyses). Our data demonstrate that apoptotic cells target the proinﬂammatory transcriptional machinery of macrophages with which they interact, without apparent effect on proximal steps of Toll-like receptor signaling. The modulatory activity of the corpse is manifest as an immediate-early inhibition of proinﬂammatory cytokine gene transcription, and is exerted directly upon binding to the macrophage, independent of subsequent engulfment and soluble factor involvement. Recognition and inﬂammatory modulation represent key elements of an innate immune response that discriminates live from effete cells, and without regard to self. The Journal of Immunology, 2004, 172: 880–889.
Effects of Seven Plant Essential Oils on Mortalities of Chicken Lice ( Lipeurus caponis L.) Adult

Chicken lice ( Lipeurus caponis L.) are external parasite of chicken and farmers often use malathion and carbaryl insecticides to control this parasite. However, the use of chemical insecticides may result in direct toxicity to chicken or contamination in chicken meats. Thus, this study investigated the effect of seven plant essential oils (EOs) against adult chicken lice. Contact bioassay was performed by laying 10 adult chicken lice on treated filter paper added with EOs at concentrations of 0 (95% ethanol as a control), 0.079, 0.157, 0.236 and 0.314  l  cm -2 . Mortality percentages were observed at 3, 6 and 12 h intervals after the treatments. Clove, cinnamon, turmeric and star anise EOs were able to eliminate the lice completely (100% mortalities) at 12 h exposure which were higher than lemon grass, citronella grass and piper EOs. Clove EO was the most effective oil with LC 50 of 0.132, 0.085 and 0.039  l  cm -2 at 3, 6 and 12 h, respectively. Furthermore, clove EO at the 0.157  l  cm -2 showed the highest mortalities with LT 50 at 1.438 h. Our study suggests that clove EO could be used as an alternative medicinal insecticide to control chicken lice in farms.
A Rab11- and Microtubule-Dependent Mechanism for Cytoplasmic Transport of Inﬂuenza A Virus Viral RNA (cid:1)

The viral RNA (vRNA) genome of inﬂuenza A virus is replicated in the nucleus, exported to the cytoplasm as ribonucleoproteins (RNPs), and trafﬁcked to the plasma membrane through uncertain means. Using ﬂuorescent in situ hybridization to detect vRNA as well as the live cell imaging of ﬂuorescently labeled RNPs, we show that an early event in vRNA cytoplasmic trafﬁcking involves accumulation near the microtubule organizing center in multiple cell types and viral strains. Here, RNPs colocalized with Rab11, a pericentriolar recycling endosome marker. Cytoplasmic RNP localization was perturbed by inhibitors of vesicular trafﬁcking, microtubules, or the short interfering RNA-mediated depletion of Rab11. Green ﬂuorescent protein (GFP)-tagged RNPs in living cells demonstrated rapid, bidirectional, and saltatory movement, which is characteristic of microtubule-based transport, and also cotrafﬁcked with ﬂuorescent Rab11. Coprecipitation experiments showed an interaction between RNPs and the GTP-bound form of Rab11, potentially mediated via the PB2 subunit of the polymerase. We propose blotting. Pulldowns of GFP-tagged GFP-Trap dishes of transfected where were 48 protease glutathione Sepharose (Amersham Biosciences) 30 supernatant was bound to GFP-Trap and binding NP-40 substitute, NaCl, protease inhibitor and l chloroform directly precipitation. Speciﬁc RNA species reverse transcriptase-ra- diolabeled primer extension followed and autoradiography essentially as described previously blotting ac- cording to standard procedures and using a LiCor Biosciences Odyssey near-infrared platform as described previously used mouse monoclonal Rab11a (ab78337; GFP (JL8; 632380; Clontech), and inﬂuenza M2 (14C2;
deficiency in a murine model induces hypertrophy and higher basal gastric acid output.

Pituitary adenylate cyclase-activating polypeptide (PACAP) has been shown to increase the histamine release from gastric enterochromaffin-like (ECL) cells and promote gastric acid secretion in rats. In contrast, in mice, PACAP has been demonstrated to induce a decrease of gastric acid secretion, an effect presumably due to somatostatin release. To more clearly define the role of PACAP in the regulation of gastric acid output, a knockout mouse model for the PACAP-specific receptor PAC1 was applied in this study. Measurements of the basal and stimulated gastric acid secretion and morphological studies on the gastric mucosa were performed in both wild-type and PAC1-deficient mice. Compared with the wild-type mice, the PAC1-deficient mice showed a nearly threefold higher basal gastric acid output, increased gastric mucosa thickness and glands height, and proportional increases in parietal and total cell counts in the gastric mucosa. The PAC1-deficient mice also showed a trend of increased plasma gastrin levels and gastrin gene expression in the gastric mucosa. This study indicates that the expression of PAC1 is clearly important for maintaining the homeostasis of gastric acid secretion. Loss of PACAP receptor during development may lead to a compensatory mechanism regulating gastric acid secretion.
Ajuste recursivo con transformaciones invariantes y bootstrapping: El caso de una caminata aleatoria con intercepto

Usamos simulaciones de Monte Carlo para estudiar el desempeno de la prueba de raiz unitaria de Shin-So (DFSS) bajo los enfoques de transformaciones invariantes y el bootstrapping. Si la hipotesis alternativa es un proceso estacionario alrededor de una tendencia lineal, entonces la prueba bootstrap parametrica es la mejor en terminos de la potencia estadistica. Sin embargo, si transformamos las observaciones para construir una prueba invariante, entonces la prueba DFSS es la mejor. Por consiguiente, la recomendacion es usar transformaciones invariantes de la prueba de raiz unitaria de Shin-So debido a que su ejecucion es directa y de menor coste.
in Mice TLR3 Induces Severe Small Intestinal Injury Recognition of Double-Stranded RNA by

The role of TLRs on intestinal epithelial cells (IECs) is controversial, and the mechanisms by which TLRs inﬂuence mucosal homeostasis are obscure. In this study, we report that genomic dsRNA from rotavirus, and its synthetic analog polyinosinic-polycytidylic acid (poly(I:C)), induce severe mucosal injury in the small intestine. Upon engaging TLR3 on IECs, dsRNA triggers IECs to secrete IL-15, which functions to increase the percentage of CD3 (cid:1) NK1.1 (cid:1) intestinal intraepithelial lymphocytes (IELs) and enhances the cytotoxicity of IELs. Moreover, The CD3 (cid:1) NK1.1 (cid:1) IELs are proved as CD8 (cid:2)(cid:2) (cid:1) IELs. These results provide direct evidence that abnormal TLR3 signaling contributes to breaking down mucosal homeostasis and the ﬁrst evidence of pathogenic effects mediated by CD8 (cid:2)(cid:2) (cid:1) IELs. The data also suggest that genomic dsRNA may be involved in the pathogenesis of acute rotavirus gastroenteritis. The Journal of Immunology, 2007, 178: 4548–4556. poly(I:C) Our ﬁndings depletion of IELs mucosal but depletion of CD3 (cid:4) NK1.1 (cid:3) IELs using the anti-AsGM1 Ab had minimal effect. These results show that CD3 (cid:3) NK1.1 (cid:3) IELs play a critical role in poly(I:C)-induced small intestinal injury.
GPU-accelerated Signal Processing for Search of Pulsars

—This short paper describes the accelerated signal processing for the search of radio pulsars recorded by Big Scanning Antenna telescope at Pushchino Radio Astronomy Observatory. Acceleration is achieved by parallelization of computations on multiprocessor systems and, especially, on Graphics Processing Units. Parallelization provides computational speeds sufﬁcient for signal processing and pulsar detection in the observations in real-time.
University of Birmingham The effects of cobalt-chromium-molybdenum wear debris in vitro on serum cytokine profiles and T cell repertoire

Cobalt-chromium-molybdenum (CoCrMo) alloy-based metal-on-metal prostheses have been the implant of choice for total hip replacement in younger patients. However 6.2% of patients require revision of their CoCrMo total hip replacement (THR) implant within five years of surgery and their use was restricted in 2013. We aimed to determine if there were individual differences in the immune response to wear debris that might indicate a poor outcome with a CoCrMo prosthesis. Blood from 22 donors was incubated with CoCrMo particles (>99.9% less than 10µm diameter) generated by a wear simulator for 24h. T cell phenotype was assessed by immunostaining and secretion of 8 different pro-and anti-inflammatory cytokines was measured using multiplex technology. Clear differences were seen between individuals in the induction of Th17 and Th1 responses, with some donors showing pro-inflammatory responses (increased IL17 or IFN γ ) and others showing anti-inflammatory responses (decreased IL17 or IFN γ ). The only differences seen for gender and age related to increased IL-10 expression from T cells in females ( p =0.008) and a trend towards decreased IL-6 expression systemically for older donors ( p =0.058). We conclude that individuals show differential responses to CoCrMo wear debris and that these responses could give early indications of the suitability of the patient for a metal-on-metal prosthesis.
Institutional Knowledge at Singapore Management University Institutional Knowledge at Singapore Management University

User-generated images (UGIs) are currently proliferating within social networks. These images contain multi-dimensional data, including the image itself, text and the social links of the owner. UGIs can be utilized for self-presentation, news dissemination and other purposes, and the quality of the image should be able to reveal these social functionalities. However, it is challenging to predict UGI quality utilizing existing models, such as image quality assessment, recommender systems or others, because these models have difﬁcul-ties processing multi-dimensional data simultaneously. To address this problem, we pro-pose a multi-dimensional image quality prediction model for UGIs in social networks. In this model, we build two sub-models for presentation measurement and distortion measurement. The text (i.e., tags and comments), social links and UGIs are processed by these two models separately, and the results of the models are pooled to obtain a ﬁnal quality score. Both subjective and objective experiments are then arranged for ground truth data and performance assessment, respectively. Participants are asked to make judgments about 55 UGIs randomly selected from social networks, and the ground truth dataset is based on these subjective experiments. The objective experiments are performed to verify the performance of our model. The results indicate that the Pearson correlation parameter between the predicted score and the ground truth data is 0.5779, which suggests that the proposed model can be implemented to predict image quality in practical environments
Best practices in serious games: Gamification strategies to support public participation in citizen observatories

1 XTeam Software Solutions. via Roma 833, 45020 Giacciano con Baruchella (Rovigo), Italy – e-mail: silvia.brandalesi@xteamsoftware.com, tamascelli@xteamsoftware.com 2 Aalborg University. A. C. Meyers Vænge 15, 2450 Copenhagen, Denmark – e-mail: lsi@create.aau. dk 3 Institute of Communication & Computer Systems (ICCS). 9, Iroon Politechniou str. Polytechnic Campus, 15773 Zografou, Athens, Greece – e-mail: valantis.tsiakos@iccs.gr, maria.krommyda@iccs.gr, atsertou@iccs.gr, a.amditis@iccs.gr 4 Carr Communications Ltd. 5 Northumberland Road, Ballsbridge, Dublin 4, Ireland – e-mail: amy@carrcommunications.ie
Resource-aware video multicasting via access gateways in wireless mesh networks

This paper studies video multicasting in large scale areas using wireless mesh networks. The focus is on the use of Internet access gateways that allow a choice of alternative routes to avoid potentially lengthy multi-hop wireless paths with low capacity. A set of heuristic-based algorithms are described that together aim to maximize network capacity: the two-tier integrated architecture algorithm, the weighted gateway uploading algorithm, the link-controlled routing tree algorithm, and the alternative channel assignment algorithm. These algorithms use different approaches to arrange multicast group members into a clustered and two-tier integrated architecture in which network protocols can make use of multiple gateways to improve system throughput. Simulation results are used to determine the performance of the different approaches.
A NEW APPROACH IN WEBSITE FRAUD DEDUCTION BY CLASSIFYING FEATURE SELECTION METHOD

: This paper is used to detect the website fraud by using popup window. Because Website Site Fraud Detection is a crucial point that applies to numerous ventures including the monetary areas, banking, government organizations, protection, and law requirement, and other industries also. In spite of battles with respect to the grieved associations, countless amounts are squandered to misrepresentation every year. Pop-up windows are mostly generated by the websites. Web traffic is measured in visits, sometimes called "sessions," and is a common way to measure an online business effectiveness at attracting an audience. Website traffic refers to web users who visit a website. By using pop-up window and website traffic we are going to detect the fraud which are occurring in website.
A 9-year Experience of Laparoscopic Herniorrhaphy at Fort Prajaksilapakom Hospital

Objective: This study was to review the overall outcome of the laparoscopic totally extraperitoneal (TEP) repair for inguinal hernia during the past 9 years. Methods: This retrospective study was undertaken in 107 patients with 119 hernial defects. A single surgeon had used TEP approach from March 2000 - October 2008. The medical records were reviewed in the following data categories: gender, age, weight, duration of symptom, diagnosis, underlying condition, previous surgery, operation time, number of staples, drain applying, complication, and follow up time. Results: The average age of 107 patients was 60.1 years old. There were 98 unilaterals and 9 bilaterals. The indirect hernia was in 93 patients (78.1%) and direct hernia was in 26 patients (21.9%). Of 119 hernia repairs there were 3 patients converted to open herniorrhaphy (2.8%) and one of these three had small bowel injury (0.9%). The recurrence was occurred in 1 patient (0.9%). The mean operation time was 72.74 minutes (40-160), LOS 2.85 days (1-8). The complication rate was 18.9% (20 patients), most of them were minor conditions such as small hematoma (10), seroma (2), and subcutaneous emphysema (1). There was no mortality with an average 38.8 months follow up (1-106 months). Conclusion: The TEP approach was successful, highly safe and efficient due to significant low recurrent rate and no mortality while comparing to either other laparoscopic hernioplasty or open tension free repair. However, the outcomes were dependent on how to select patients, the expertise of surgeon, and surgical technique modification.
Evaluation of Indoor Navigation for the Visually Impaired - User Experience and Requirements

There are many challenges regarding indoor navigation in unknown areas, and the difficulty is higher for the visually impaired. One significant question is the amount of information needed for visually impaired to independently and successfully navigate through complex buildings. In this study, a prototype application initially developed by MazeMap was further developed and maintained. This application was then used to test the amount of information needed and how this information should be presented to the user, and in what detail. An experiment, a survey and interviews were conducted with three participants. The experiment consisted of having the participants testing the prototype application while navigating through a building at Gløshaugen, a campus at the Norwegian University of Science and Technology (NTNU). In the survey and during the interviews, they provided feedback on the application and answered questions regarding their challenges for indoor navigation. The application was evaluated using the Technology Acceptance Model (TAM), focusing on Perceived Usefulness and Perceived Ease of Use. Based on the TAM evaluation, this thesis concluded that the most important issue that need to be addressed is allowing the user to verify that the instructions are followed correctly. This can be executed by making use of electronic compass and precise indoor positioning systems in the application. Another possibility is using objects such as walls, doors, pillars or other structures as the endpoints in each instruction, since these are detectable with a white cane or guide dog. The research also stresses the importance of giving control to the users regarding the amount of information presented. This is important as different situations and users need different amounts of information.
Point of View Ventricular Function Is the Total More Than the Sum of the Parts?

F undamental to evolution in biology has been the trend toward growing complexity, from the molecular to the cellular level, toward multicellularity, and finally the whole-organ level. At any level, biological systems are composed of interacting subsystems, which in turn are also systems, albeit on a smaller scale. Interaction between subsystems may add entirely new properties to the composite system. In the cardiovascular system, consideration of the interaction between the left ventricle and arterial load and the efficiency of this interaction is not new.2-4 In the heart, already on smaller scales, several interaction processes seem to be incorporated as we move up from a subcellular to the whole-organ level (Figure 1). From the subsequent discussion on ventricular function, it will follow that interaction processes constitute an essential and obligatory property of ventricular function, in which the mechanisms involved are still largely unknown. Therefore, one cannot easily extrapolate from mere subcellular or molecular events to whole-organ function without considering these interaction processes at increasingly larger levels. Several interaction processes have been considered at different levels. We will focus on three of these: Upgrading of system performance through interaction of subsystems, uniformity of system performance through interaction of subsystems, and modulation of system performance through cell communication.
Inﬂuence of the Education Level on Health of Elderly People

—In the present work, the relation between the level of education of elderly people and their health and quality of life has been studied. The studies have been performed in Poland. The collected data have been analyzed using the World Health Organization Quality of Life-BREF (WHOQOL-BREF) questionnaire (an abbreviated version of the WHOQOL-100), and the Geriatric Depression Scale. In both cases, we have observed a large inﬂuence of the education level on health. In most cases, the higher the education, the more positive the results. A large inﬂuence of the marital status on the overall quality of life and general health of the Polish pensioners has also been observed.