Miracle-dz/UniFAR-FTUs huggingface dataset:
Integrating GPS, GYRO, vehicle speed sensor, and digital map to provide accurate and real-time position in an intelligent navigation system

The global positioning system (GPS) has become the most extensively used positioning and navigation tool in the world. Applications of GPS abound in surveying, mapping, transportation, agriculture, military planning, GIS, and the geosciences. However, the positional and elevation accuracy of any given GPS location is prone to error, due to a number of factors. The applications of Global Positioning System (GPS) positioning is more and more popular, especially the intelligent navigation system which relies on GPS and Dead Reckoning technology is developing quickly for future huge market in China. In this paper a practical combined positioning model of GPS/DR/MM is put forward, which integrates GPS, Gyro, Vehicle Speed Sensor (VSS) and digital navigation maps to provide accurate and real-time position for intelligent navigation system. This model is designed for automotive navigation system making use of Kalman filter to improve position and map matching veracity by means of filtering raw GPS and DR signals, and then map-matching technology is used to provide map coordinates for map displaying. In practical examples, for illustrating the validity of the model, several experiments and their results of integrated GPS/DR positioning in intelligent navigation system will be shown for the conclusion that Kalman Filter based GPS/DR integrating position approach is necessary, feasible and efficient for intelligent navigation application. Certainly, this combined positioning model, similar to other model, can not resolve all situation issues. Finally, some suggestions are given for further improving integrated GPS/DR/MM application.
MicroRNA‑652 promotes cell proliferation and osteosarcoma invasion by directly targeting KLF9

Previous studies have demonstrated that various microRNAs (miRNAs or miRs) are abnormally expressed in osteosarcoma (OS) and serve roles in its malignant development. An in‑depth understanding of the specific roles of dysregulated miRNAs in OS may be important for cancer research and the identification of novel therapeutic targets. In the current study, reverse transcription-quantitative PCR was performed to determine miR-652 expression in OS tissues and cell lines. Cell Counting Kit-8 and Transwell invasion assays were used for assessing the effect of miR-652 on the proliferation and invasion of OS cells. Herein, miR-652 expression was assessed in OS and the effects and molecular mechanisms of miR-652 in OS cells were examined. The results revealed that miR-652 expression was significantly upregulated in OS tissues and cell lines compared with adjacent normal tissues and a normal human osteoblast cell line. Furthermore, miR-652 downregulation inhibited the proliferation and invasion of OS cells. miR-652 was also demonstrated to directly interact with the 3'-untranslated region of kruppel-like factor 9 (KLF9) and miR-652 negatively regulated KLF9 expression in OS cells. miR-652 and KLF9 mRNA levels were also revealed to be inversely correlated in OS tissues. Treatment with KLF9 small interfering RNA abolished the suppression of OS proliferation and invasion induced by miR-652 downregulation. miR-652 may serve an oncogenic role in OS cells by targeting KLF9 directly. The results also indicated that miR-652 may be an effective novel therapeutic target for the treatment of patients with OS.
Management of Environmental Problems and Hazards in Nigeria

Part 1 Effective survival measures for environmental and ecological hazards in Nigeria: erosion phenomenon and development dynamics in South-Eastern Nigeria urban environmental factors of flooding - a preliminary enquiry of Awka Capital territory Anambra State - the place of governmental knowledge for survival effective survival measures against natural hazards in settled areas land improvement in disaster areas - the role of agricultural practices noise - an element of environmental pollution the causes and consequences of deforestation of the rainforest belt of Nigeria air pollution - a threat to human survival environmental challenge - emphasizing architectural design environment, environmental problems and their effects on human life - from awareness to action mapping the Enugu environment for identification of environmental hazards and mitigating the effects of such hazards development, the environment and our ecological wisdom. Prt 2 Poverty and environmental degradation: rural poverty and environment degradation urban poverty and environmental degradation in Nigerian cities. Part 3 The role of government and citizens in environmental management: towards environmental awareness in Nigeria government efforts in environmental management in Nigeria mitigating the effects of environmental hazards in settled areas environmental problems and their management - the role of the government and citizens the role of government and citizens in erosion control offical mechanism for implementing environmental impact analysis in Nigeria the girl child - her education and training for sustainable environmental management and development population growth and environment. Part 4 Problems and prospects of sustainable development of the Nigerian environment: towards an integrated urban development and environmental management strategies for sustainable cities in Nigeria - a case study of Onitsha towards improving degraded urban neighbourhoods in Nigeria - prospects for resident participation.
Correlation between post-procedure residual thrombus and clinical outcome in deep vein thrombosis patients receiving pharmacomechanical thrombolysis in a multicenter randomized trial

Purpose: To evaluate relationships between immediate anatomic outcomes and clinical outcomes of pharmacomechanical catheter-directed venous thrombolysis (PCDT). Materials and Methods: Venograms from 317 proximal DVT patients who received PCDT in a multicenter randomized trial were reviewed. Quantitative thrombus resolution was assessed by independent readers using a modified Marder scale. The physician operators recorded their visual assessments of thrombus regression and venous flow. These immediate post-procedure anatomic outcomes were correlated with patient outcomes at 1, 12, and 24 months. Results: PCDT produced substantial thrombus removal (p < 0.001 for comparisons of pre-PCDT and post-PCDT thrombus scores in all segments evaluated). At procedure end, spontaneous anterograde venous flow was present in 99% of iliofemoral venous segments and in 89% of femoral-popliteal venous segments. For the overall proximal DVT population, and for the femoral-popliteal DVT subgroup, post-PCDT thrombus volume did not correlate with 1-month or 24-month outcomes. For the iliofemoral DVT subgroup, post-PCDT thrombus volume did not correlate with 24-month PTS occurrence but did correlate with 24-month Villalta PTS severity (p=0.0098), with trends toward improved symptom status and venous disease-specific quality of life (QOL) over 1 and 24 months. Post-PCDT thrombus volume did not correlate with 12-month valvular reflux. Conclusion: PCDT successfully removes thrombus in acute proximal DVT. However, the residual thrombus burden at procedure end does not correlate with the occurrence of PTS during the subsequent 24 months. In iliofemoral DVT, lower residual thrombus burden correlates with reduced PTS severity and probably also with improved venous QOL and fewer early symptoms.
ARTICULAÇÃO ENTRE OS NÍVEIS DE ATENÇÃO DOS SERVIÇOS DE SAÚDE NA REGIÃO METROPOLITANA DE CURITIBA: DESAFIOS PARA OS GESTORES

A provisao adequada de servicos de atencao primaria a saude e o acesso aos servicos especializados, tambem usualmente referidos como de media/alta complexidade, apresenta-se como uma dificuldade em varios municipios brasileiros, tendo em vista as questoes gerenciais envolvidas que incluem a forca de trabalho, os custos e a densidade tecnologica exigida. Este estudo objetivou compreender a pratica discursiva de gestores em relacao a articulacao entre os niveis de atencao primaria e de media/alta complexidade dos servicos publicos de saude na Regiao Metropolitana de Curitiba (RMC). Realizou-se um estudo exploratorio de abordagem qualitativa, com dezessete gestores de saude da RMC. Os dados discursivos foram coletados por meio de entrevista semi-estruturada, sendo processados pelo metodo de analise de discurso. A interpretacao do material permitiu a classificacao dos dados discursivos, que foram agrupados em categorias: atencao primaria municipal, acesso na media complexidade, atendimento hospitalar, saude bucal e articulacao politica. A analise demonstrou que os municipios se encontram em diferentes estagios de implantacao e organizacao da atencao primaria. A ESF foi citada pela maioria como forma de reorganizacao da APS e oferta de servicos mais resolutivos. Outra preocupacao dos secretarios municipais e a pressao exercida pela demanda por consultas medicas e a desvalorizacao das acoes desenvolvidas pelo restante da equipe multiprofissional de saude, fato que em certa medida tambem fragiliza o processo de implantacao, nao apenas da ESF, mas dos conceitos e atributos internacionais que definem a APS de qualidade, incluindo a educacao, a promocao da saude e a prevencao de doencas, por meio de agentes que atuam em varias esferas, algumas inclusive extrapolando o setor saude e alcancando o plano intersetorial. A dificuldade no acesso aos servicos de media/alta complexidade promove interrupcao na continuidade das linhas de cuidado, as quais visam a integralidade da atencao em saude e implicam na adequada coordenacao da atencao primaria articulada a atencao especializada de segundo e/ou terceiro niveis de densidade tecnologica. Finalmente, os gestores apontam como necessaria a regionalizacao dos servicos de media/alta complexidade, e em alguns casos, ate mesmo a micro regionalizacao, uma vez que se trata de uma area de abrangencia tao grande quanto as diferencas entre as realidades de alguns municipios aqui estudados.
The application of computational modeling to data visualization

Researchers have argued that perceptual issues are important in determining what makes an effective visualization, but generally only provide descriptive guidelines for transforming perceptual theory into practical designs. In order to bridge the gap between theory and practice in a more rigorous way, a computational model of the primary visual cortex is used to explore the perception of data visualizations. A method is presented for automatically evaluating and optimizing data visualizations for an analytical task using a computational model of human vision. The method relies on a neural network simulation of early perceptual processing in the retina and visual cortex. The neural activity resulting from viewing an information visualization is simulated and evaluated to produce metrics of visualization effectiveness for analytical tasks. Visualization optimization is achieved by applying these effectiveness metrics as the utility function in a hill-climbing algorithm. This method is applied to the evaluation and optimization of two visualization types: 2D flow visualizations and node-link graph visualizations. The computational perceptual model is applied to various visual representations of flow fields evaluated using the advection task of Laidlaw et al. The predictive power of the model is examined by comparing its performance to that of human subjects on the advection task using four flow visualization types. The results show the same overall pattern for humans and the model. In both cases, the best performance was obtained from visualizations containing aligned visual edges. Flow visualization optimization is done using both streaklet-based and pixel-based visualization parameterizations. An emergent property of the streaklet-based optimization is head-to-tail streaklet alignment, the pixel-based parameterization results in a LIC-like result. The model is also applied to node-link graph diagram visualizations for a node connectivity task using two-layer node-link diagrams. The model evaluation of node-link graph visualizations correlates with human performance, in terms of both accuracy and response time. Node-link graph visualizations are optimized using the perceptual model. The optimized node-link diagrams exhibit the aesthetic properties associated with good node-link diagram design, such as straight edges, minimal edge crossings, and maximal crossing angles, and yields empirically better performance on the node connectivity task.
AAN position statement:

Patients, clinicians, and hospitals have undergone monumental changes during the coronavirus disease 2019 (COVID-19) pandemic. This crisis has forced us to consider the obligations that we neurologists have to our individual patients as well as the greater community. By returning to our fundamental understanding of these duties, we can ensure that we are providing the most ethically appropriate contingency and crisis care possible. We recommend specific adaptations to both the inpatient and outpatient settings, as well as changes to medical and trainee education. Furthermore, we explore the daunting but potentially necessary implementation of scare resource allocation protocols. As the pandemic evolves, we will need to adapt continuously to these rapidly changing circumstances and consider both national and regional standards and variation.
Mid-crustal controls on episodic stress-field rotation around major reverse, normal and strike-slip faults

Abstract Numerical models are used to investigate the geometry of coseismic stress-field perturbation in the crust surrounding a reverse fault, a normal fault and a strike-slip fault. The results predict a coseismic stress drop in the upper crust and loading to high stress below the brittle–ductile transition (BDT) due to the taper-off in fault slip. Coseismic stress deflections occur for each fault type as a result of the coseismic stress redistribution and is at a maximum in the middle crust where fault slip tapers-off. The zone of high-stress deflection extends downwards to the base of the crust. During the post-seismic interval, the stress-field geometry recovers towards the pre-earthquake stress state, but simple stress-field geometries cannot be re-established. The numerical results indicate that: (1) stress deflection due to slip taper-off below the BDT is important for the stress perturbation throughout the crust; (2) predictions for coseismic stress deflection exclusively based on the fault-parallel shear-stress drop ratio systematically underestimate stress deflection in the entire crust; (3) stress rotation is persistent throughout the crust in seismically active regions; and (4) the geometry of secondary faults is expected to be affected by the perturbed stress field.
Northward Intrusion of Antarctic Intermediate Water in the Western Pacific

Abstract The northward intrusion of Antarctic Intermediate Water (AAIW) is examined using historical data combined with synoptic observations from a repeated hydrographic section in the western Pacific Ocean. The results of this analysis suggest that AAIW is traced as a salinity minimum to only about 15°N via the New Guinea Coastal Undercurrent and the Mindanao Undercurrent. There is no northward extension of AAIW farther to the north along the western boundary. Although relatively high oxygen water does exist in the Okinawa Trough, it is connected with high-oxygen water in the South China Sea (SCS) through the Luzon Strait but not from the south as an extension of AAIW. Local circulation seems to play an essential role in localizing the oxygen maximum in the SCS. Evidence exists to suggest that high-oxygen water enters the SCS as part of the Pacific deep water around the still depth (∼2000 m) of the Luzon Strait; from there, part of it upwells and is entrained into shallower isopycnal surfaces by vertica.
Ocupaciones humanas tempranas y condiciones paleoambientales en el Desierto de Atacama durante la transición Pleistoceno-Holoceno

El Desierto de Atacama (Arica a Taltal, 18°-25° S), uno de los ambientes más áridos del planeta, ha sido considerado un hábitat inhóspito y, por ende, una barrera importante para los grupos de cazadores- recolectores que migraron a Sudamérica a fines delPleistoceno. Recientes datos paleocológicos y geomorfológicos, resumidos aquí, evidencian que durante la transición Pleistoceno-Holoceno (c. 17.500-9500 cal AP) algunos sectores del Atacama fueron mucho más húmedos y tuvieron mayor bioproductividad que hoy, lo que incrementa las posibilidades de encontrar sitios tempranos. Aquí, en primer lugar, describimos el ambiente actual del Atacama y lo comparamos con sus condiciones ambientales pasadas. En segundo lugar, presentamos las evidencias arqueológicas que dan cuenta de la colonización humana de la costa hiperárida (0-900 metros sobre el nivel del mar), la Depresión Intermedia (900-2200 metros sobre el nivel del mar), la precordillera (2200-3500 metros sobre el nivel del mar) y el altiplano (>3500 metros sobre el nivel del mar). Por último, discutimos algunas de las posibles rutas migratorias para el poblamiento de Sudamérica.
The Role of Fisheries-Induced Evolution

In their Policy Forum (“Managing evolving fish stocks,” 23 November 2007, p. [1247][1]), C. Jorgensen et al. propose evolutionary impact assessments (EvoIAs) as a general tool for managing evolving resources. The basis for their proposal is that fisheries-induced evolution (FIE) is the most
Robustness and evolvability in the B-system of flower development.

BACKGROUND Gene duplication has often been invoked as a key mechanism responsible for evolution of new morphologies. The floral homeotic B-group gene family has undergone a number of gene duplication events, and yet the functions of these genes appear to be largely conserved. However, detailed comparative analysis has indicated that such duplicate genes have considerable cryptic variability in their functions. In the Solanaceae, two duplicate B-group gene lineages have been retained in three subfamilies. Comparisons of orthologous genes across members of the Solanaceae have demonstrated that the combined function of all four B-gene members is to establish petal and stamen identity, but that this function was partitioned differently in each species. These observations emphasize both the robustness and the evolvability of the B-system. SCOPE We provide an overview of how the B-function genes can robustly specify petal and stamen identity and at the same time evolve through changes in protein-protein interaction, gene expression patterns, copy number variation or alterations in the downstream genes they control. By using mathematical models we explore regulatory differences between species and how these impose constraints on downstream gene regulation. CONCLUSIONS Evolvability of the B-genes can be understood through the multiple ways in which the B-system can be robust. Quantitative approaches should allow for the incorporation of more biological realism in the representations of these regulatory systems and this should contribute to understanding the constraints under which different B-systems can function and evolve. This, in turn, can provide a better understanding of the ways in which B-genes have contributed to flower diversity.
Application of Seismic Interferometry in Crystalline Rocks - A Case Study From the Lalor Mining Area, Canada

Approximately 300 hours of ambient noise data covering an area of 4 km² were acquired over the Lalor mining area, Canada, to test the capability of seismic interferometry to image ore deposits in the crystalline rock environment. The interferometry survey consists of 336 receivers located along 9 parallel lines oriented southwest-to northeast and 7 southeast-to-northwest lines. Alongside the ambient noise survey, a larger 3D active source seismic survey was also acquired in the area and used to evaluate the interferometry results. The seismic wave field is retrieved by crosscorrelating the noise between all receiver locations in each hourly segment of passive seismic data. The crosscorrelated results of all segments are spatially summed to generate virtual shot gathers. The virtual data is processed along all 2D lines with conventional methods similar to those applied to active 3D data. The DMO-stacked section obtained reveals a number of events, some more coherent than observed on the similarly processed active seismic section. Of particular interest is an event possibly associated with the massive sulphides. A comparable event is also observed on the active seismic data. These results demonstrate the benefits of ambient noise measurements in crystalline rock environment for mineral exploration purposes.
Our knowledge of the physico‐chemistry of aerosols in the undisturbed marine environment

A survey is given of our present knowledge of the marine aerosol. On the basis of the aerosol size distribution in undisturbed marine, environments, five different components of the aerosol are discussed: particles with radii larger than 20 μ, sea spray particles, tropospheric background particles, mineral dust particles, and particles with radii smaller than 0.03 μ. Evidence is presented that the troposphere over the oceans is filled with a fairly uniform background aerosol on which the sea spray aerosol is superimposed only within the lowest kilometers above the sea surface. The sea spray component is discussed in detail with respect to size distribution, production, and chemical composition. The various components of the background aerosol seem to be either of continental origin or produced within the atmosphere. New data are presented on the mineral dust component over the Atlantic Ocean that originates from the Sahara.
Return to Sport Tests’ Prognostic Value for Reinjury Risk after Anterior Cruciate Ligament Reconstruction: A Systematic Review

IN IC A Return to Sport Tests’ Prognostic Value for Reinjury Risk after Anterior Cruciate Ligament Reconstruction: A Systematic Review L SC EN C ES EVANS YAYRA KWAKU ASHIGBI, WINFRIED BANZER, and DANIEL NIEDERER Division of Preventive and Sports Medicine, Institute of Occupational, Social and Environmental Medicine, Goethe University, Frankfurt am Main, GERMANY; Department of Sports Medicine and Exercise Physiology, Institute of Sports Sciences, Goethe University, Frankfurt am Main, GERMANY; and Department of Physiotherapy and Rehabilitation Sciences, School of Allied Health Sciences, University of Health and Allied Sciences, GHANA