Miracle-dz/UniFAR-FTUs huggingface dataset:
Risk of death following kidney allograft failure: a systematic review and meta-analysis of cohort studies

Background. People with kidney allograft failure represent an increasing fraction of all those starting dialysis therapy. We sought to summarize prognosis following kidney allograft failure and identify potentially bene ﬁ cial interventions or modi ﬁ able risk factors. Methods. We searched MEDLINE and EMBASE (inception to 1 October 2013) and article reference lists without language restriction and selected cohort studies of all-cause mortality and fatal infection-related and cardiovascular events in people starting dialysis following kidney allograft failure. Two reviewers independently extracted data on study design, participant characteristics, dialysis modality, transplant nephrectomy, immunosuppression strategy, transplant-naive comparators and risk of bias. Discrepancies were resolved with a third reviewer. Results. Forty studies comprising 249 716 participants met the inclusion criteria. The ﬁ rst year of dialysis therapy was associated with the highest mortality. By random effects meta-analysis, annual risk of death, from years 1 to 4, was 0.12 [95% con ﬁ dence interval (95% CI): 0.09 – 0.15], 0.06 (95% CI: 0.05 – 0.07), 0.05 (95% CI: 0.04 – 0.06) and 0.05 (95% CI: 0.04 – 0.06), respectively. We found high heterogeneity in each meta-analysis, which remained unexplained by prespeci ﬁ ed subgroup analyses. We could not ﬁ nd suf ﬁ cient information to summarize the risk for fatal infection-related and cardiovascular events, or to test the role of transplant nephrectomy or different immunosuppressive strategies. Risk of bias was high, especially participation bias. Conclusion. Mortality is higher during the ﬁ rst year of dialysis treatment following kidney allograft failure than in subsequent years. Insuf ﬁ cient data are available to assess factors or interventions potentially impacting prognosis following kidney allograft failure. In a culture promoting transplantation, clinical research of different models of care in this growing high-risk population should be a research priority. ABSTRACT Background. Kidney transplantation increases the chances for pregnancy and live birth for women with end-stage kidney disease. The aims of this study were to describe the outcomes of pregnancies in women with a kidney transplant and to evaluate the impact on anti-human
A NONLINEAR PROGRAMMING PROBLEM USING BRANCH AND BOUND METHOD

Taking the clue from the pioneer work of Tarray and Singh (2015) we have suggested a new stratified randomized response model. In this paper the problem of optimal allocation in stratified random sampling where randomized response technique is used in presence of non response. The problem is formulated as a Nonlinear Programming Problem (NLPP) and is solved using Branch and Bound method. Also the results are formulated through LINGO.
MANAGING DIABETES MELLITUS: A WAY FORWARD

: Diabetes Mellitus (DM) is a group of metabolic diseases characterized by an elevated blood glucose level – resulting from defects in insulin secretion, in insulin action or both. Diabetes Mellitus is not a pathogenic entity but a group of etiologically different metabolic defects that share the phenotype of hyperglycemia. Several distinct types of DM exist and are caused by complex interaction of genetic factors and life style choices. The metabolic dysregulation associated with DM causes secondary pathophysiologic changes in multiple organ systems that impose a tremendous burden on the individual with diabetes and on the health care system. Intensive diabetes management has set the goal of improvement of glycemic control, which reduces complications associated with the diseases. A strict control of blood glucose levels (Ideally HbA1c< 7% mean plasma glucose level, < 150 mg/dl) delays the onset and progression of diabetic neuropathy, nephropathy, retinopathy, and reduction in cardiovascular risk . Sulfonylureas (Glebenclemide, Gliclazide, Glemiperide, and tolbutamide), Biguandies (Metformin, Phenformin) are effectively used in controlling elevated blood glucose levels in oral antidiabetic therapy. Sitagliptin is a once-daily, orally active, potent and highly selective dipeptidyl peptidase-4 (DPP-4) inhibitor approved in many countries for the treatment of patients with type- 2 diabetes. Sitagliptin was the first DPP-4 inhibitor that was approved for the management of type 2 diabetes in 2007. Sitagliptin is being used as monotherapy (100 or 200 mg OD) or as an add-on to ongoing oral antidiabetic agents (OAD) in patients with type 2 diabetes with significant reduction in glycaemic levels within a few weeks. In this review, we will briefly study the different therapeutic options available for the management of Diabetes Mellitus.
Graphene as a hole transport layer for enhanced performance of P3HT: PCBM bulk heterojunction organic solar cell: a numerical simulation study

As sustainable and green energy technologies advance, academic and industrial researchers have been more interested in organic solar cells. Organic solar cells have some key advantages, such as lightweight, flexibility and cheapness that make them an ideal choice as an alternative to other types of solar cells. Bulk heterojunction solar cells combine the advantages of easier fabrication and higher conversion efficiency, making them the best structure currently. In this work P3HT: PCBM is used as the active layer material. PDINO and PFN-Br are used as the electron transport layers in this work. Graphene, which is taken as the hole transport layer in this work, is a unique material for future applications in organic photovoltaics due to its remarkable optical properties and excellent electron/hole transport properties. Corresponding to two different electron transport layers two different device configurations are studied in the work. Bulk hetero-junction organic solar cell simulation study is done using the solar cell capacitance simulator (SCAPS1D). The thickness, electron and hole mobilities, and defect density of the active layer are varied for each device configuration, and their effect on device output performance is analysed. A comparative study of device performance between the different configurations has been done.
Molecular Dynamics Simulation of Carbon Nanotube Reinforced Rubber Composites

The mechanical characteristics of nitrile butadiene rubber (NBR) and carbon nanotube (CNT) nanocomposites were investigated using molecular dynamics (MD) simulations in this study. The crystal with CNT is created with a volume fraction of about 2.47% and 4.86%. The constant strain method was used to calculate the young's modulus, shear modulus, and bulk modulus of the nanocomposite. The integration of CNT inside the rubber composite matrices increased the mechanical properties. The simulation results show that the young’s, bulk, and shear modulus of NBR 2-CNT were enhanced by about 47.10%, 28.39 %, and 17.86 % respectively when compared to the pure NBR.
Thermoregulatory and productive-related comparisons between wild type and slickhaired Puerto Rican Holstein cows

Anecdotally, wild type (WT) Puerto Rican Holstein cows perform poorly in hot weather compared with their short-haired (SLICK) counterparts, but scientific evidence supporting this claim is limited. Thus, comparisons of their vaginal temperature (VT), sweat gland size (SGS) and milk production (MP) values were made. Data were analyzed by Proc GLIMMIX and REG (SAS). During the cool season (March 2014) VT was similar in WT and SLICK cows (38.71±0.09 and 38.71±0.08 °C, respectively; P=0.9634). However, in the intermediate air temperatures (AT) season (April 2014), WT cows presented VT values 0.25° C higher than their SLICK counterparts from 1900-2100h (P=0.0213). Moreover, in the hot season (August 2015) VT was greater in WT than in SLICK cows by 0.31° C from 1800-0700h and 0900-1600h (P=0.0032), and by 0.20° C at 0800h (P=0.0584) and 1700h (P=0.0619). The VT increased linearly until AT reached 30.5° C in both WT (0.10° C per 1° C of AT; P<0.0001) and SLICK cows (0.08° C per 1° C of AT; P<0.0001). After 30.5° C, no further VT-AT relationship was observed. The WT had smaller SGS (232±12 vs. 315±9 μm perimeter; P=0.0024) and smaller MP (17.11±0.63 vs. 20.26±1.28 kg/d; P=0.0288) than the SLICK cows. The SLICK cows demonstrated superior thermoregulatory capacity, which seems to depend directly on the severity of the AT.
Comments on CrossTalk 24: Diffusion limitation of O<sub>2</sub> from microvessels into muscle doesdoes not contribute to the limitation of <math display="inline" xmlns="http://www.w3.org/1998/Math/MathML"></math>

Delineating the limiting factor at maximal exercise is difficult in humans, particularly when all body systems are reaching their maximal capacity. The contenders in this CrossTalk debate discuss the contribution of diffusion limitation to V̇O2max (Lundby & Montero, 2015; Wagner, 2015). Based on Murray’s diffusion model, cellular V̇O2max becomes limited by oxygen diffusion at interstitial PO2 values of 17–20 mmHg (Murray, 1974). Electrically stimulated single skeletal muscle fibres reduce their V̇O2max below this critical interstitial PO2 (Van der Laarse et al. 2005). The venous PO2 at V̇O2max is between 16 and 25 mmHg in the canine hindlimb (Hogan et al. 1990; Wüst et al. 2014), similar to humans (Bangsbo, 2000), inferring that critical interstitial PO2 is closely reached at V̇O2max. At V̇O2max, convective oxygen transport (blood flow) could also limit cellular respiration, but only because it fails to keep capillary PO2 at or above critical interstitial PO2 needed to avoid oxygen diffusion limitation (Bangsbo, 2000; Wüst et al. 2014). Indeed, increasing capillary PO2 by hyperoxia at constant blood flow increased V̇O2max, while decreasing capillary PO2 by hypoxia decreased V̇O2max more substantially (Wagner, 2015). The critical PO2 model therefore proves to be useful in understanding the contribution of diffusion limitation at V̇O2max. Muscle fibre size, mitochondrial capacity and myoglobin are the main determinants of critical PO2 at V̇O2max (Murray, 1974; van Wessel et al. 2010). Skeletal muscle atrophy and/or a reduced mitochondrial density in chronic patients and at altitude can therefore also be interpreted to ensure adequate oxygen diffusion when oxygen supply is reduced.
Conference News

The IEEE Symposium on Autonomous Underwater Vehicle Technology, or AUV '90, was held on June 5 and 6 at the Washington Dulles Airport Marriott Hotel in Washington, DC. The Symposium was sponsored by the Oceanic Engineering Society (OES) of the Institute of Electrical and Electronic Engineers (IEEE). With this Symposium, OES broke the tradition of addressing both Remotely Operated Vehicles (ROV) and Autonomous Undersea Vehicles (AUV) issues within one program. This Symposium was intentionally focussed on the technology issues associated with long range, fully autonomous undersea vehicles. The principal themes were addressed by the General Chairman, Charles E. Stuart of the U.S. Defense Advanced Research Projects Agency (DARPA), whose message can be paraphrased as follows: The realization of practical and economically feasible applications of unmanned undersea vehicles to both military and commercial activities seems more likely today than ever before. Investment in AUV research and development is large and growing, and developments in computers and automation have begun to produce the technologies needed to implement fully automated systems. Robust, reliable autonomous systems that can operate over long periods of time unaided by human intervention remain to be demonstrated. Pacing developments include autonomous sensor systems and controllers, high density and efficient energy and propulsion systems and practical methods for communication where interaction with humans is necessary to meet system goals. Future success depends on continuing research and development efforts like those reported in this Symposium. In the Plenary Session, these themes were reinforced by RADM David J. Wokensdorfer, USN, of the Office of the Assistant Secretary of the Navy for Research, Development and Acquisition, and Dr. David Hyde, Senior Group Vice-President of Science Applications International Corporation, who spoke on "The Role of UUVs (unmanned underwater vehicles) in Naval Warfare" and "The Potential Role of UUVs in Commercial Applications" respectively. Over 350 registrants participated in eleven technical sessions on: AUV computer architecture, AUV system issues, AUV control systems, energy systems, navigation and path planning, collision avoidance and sensors and acoustic communications. The complete text of the forty-three technical papers from nine countries is printed in Proceedings of the Autonomous Underwater Vehicle Technology Symposium, June 5 and 6, 1990, IEEE Catalog No. 90CH2856-3, Library of Congress Catalog No. 90-80540. This document was distributed to the participants upon registration, and is also available from IEEE Service Center, 445 Hoes Lane, Piscataway, NJ 08854-1331, U.S.A. (telephone 1-800-678-4333 in the U.S.A. or 201-981-0060 elsewhere). The OES is laying the groundwork for future Symposia on this subject, but no definite plans can yet be announced. Gordon Raisbeck 40 Deering Street Portland ME 04101-2212 (USA)
Geometric study of the category of matrix factorizations

We study the geometry of matrix factorizations in this dissertation. It contains two parts. The first one is a Chern-Weil style construction for the Chern character of matrix factorizations; this allows us to reproduce the Chern character in an explicit, understandable way. Some basic properties of the Chern character are also proved (via this construction) such as functoriality and that it determines a ring homomorphism from the Grothendieck group of matrix factorizations to its Hochschild homology. The second part is a reconstruction theorem of hypersurface singularities. This is given by applying a slightly modified version of Balmer's tensor triangular geometry to the homotopy category of matrix factorizations. iii DEDICATION To my parents, for their love and support. iv ACKNOWLEDGMENTS First, I would like to thank my advisor, Prof. Mark Walker, for his guidance and help throughout my years in graduate school. This dissertation would not have been possible without him. Nebraska for the support during my days in Lincoln. Last, but most importantly, I owe my deepest gratitude to my parents, who have always been there for me and I would not have made it through without them.
Ceramics Coated Metallic Materials: Methods, Properties and Applications

Surface coating can allow the bulk materials to remain unchanged, while the surface functionality is engineered to afford a more wanted characteristic. Ceramic coatings are considered as ideal coatings on metal which can significantly improve the surface properties of metal materials including anti-fouling, self-cleaning, corrosion resistance, wear resistance, oil/water separation and biocompatibility. Furthermore, various techniques have been utilized to fabricate a range of different ceramic coatings with more desirable properties on metal materials, which make the materials widely used in service environment. This chapter focus will be on the types, fabrication methods, surface properties and applications of ceramics coated metal materials.
The ultrafilter number and hm

The cardinal invariant hm is defined as the minimum size of a family of cmin-monochromatic sets that cover 2 ω (where cmin (x, y) is the parity of the biggest initial segment both x and y have in common). We prove that hm = ω1 holds in Shelah’s model of i < u, so the inequality hm < u is consistent with the axioms of ZFC. This answers a question of Thilo Weinert. We prove that the diamond principle ♦d also holds in that model.
Gravitational radiation and angular momentum flux from a slowly rotating dynamical black hole

A four-dimensional asymptotic expansion scheme is used to study the next-order effects of the nonlinearity near a spinning dynamical black hole. The angular-momentum flux and energy flux formula are then obtained by constructing the reference frame in terms of the compatible constant spinors and the compatibility of the coupling leading-order Newman-Penrose equations. By using the slow rotation and small-tide approximation for a spinning black hole, the horizon cross-section we chose is spherical symmetric. It turns out the flux formula is rather simple and can be compared with the known results. Directly from the energy flux formula of the slow-rotating dynamical horizon, we find that the physically reasonable condition on requiring the positivity of the gravitational energy flux yields that the shear will monotonically decrease with time. Thus a slow-rotating dynamical horizon will asymptotically approach an isolated horizon during late time.
Chapter 24 Arbacia

in their diet. The natural pH gradients at the CO 2 vent sites of Ischia have been used as a model system by Foo et al. (2018) to provide insights into the impact of ocean acidification ( (cid:1) 0.3 to 0.5pH T units) on the egg jelly coat of A. lixula . For the vent sea urchins, there was a significant positive relationship between the egg and jelly coat size, a relationship not seen for the eggs of females from the control site. As the egg and jelly coat size was similar between both populations, vent A. lixula jelly coats are likely to be chemically fine-tuned for the low pH environment. That the egg jelly coat of sea urchins from the vent site was robust to low pH shows intraspecific variation in this trait. This may be a maternal adaptive strategy or plastic response of the species.
Impact of EDTA application on chromium contaminated soil on yield and nutrient content in soil under maize ( Zea mays L.) cultivation

A pot experiment was conducted to assess the effect of EDTA addition on the phytoremediation efficiency of chromium contaminated soil by Zea mays L. Treatments consist of four level of Ethylene diamine tetra acetic acid (EDTA) and four level of chromium. Results showed that the different level significantly increased plant height and straw yield at different stages i.e., at 30 and 60 days after sowing respectively of maize crop. Maximum plant height at 30 DAS maize was recorded in (95.17cm) treatment in C 0 E 0 i.e., control.
Graphes parfaits : structure et algorithmes

Ce travail a pour motivation une meilleure comprehension des graphes parfaits. La preuve en 2002 de la conjecture des graphes parfaits de Claude Berge par Chudnovsky, Robertson, Seymour et Thomas a jete une lumiere nouvelle sur ce domaine de la combinatoire, mais a laisse plusieurs questions en suspens, notamment l'existence d'un algorithme combinatoire de coloration des graphes parfaits. Une paire d'amis d'un graphe est une paire de sommets telle que tous les chemins les reliant sont de longueur paire. Comme l'ont montre Fonlupt et Urhy, la contraction d'une paire amis preserve le nombre chromatique du graphe, et appliquee recursivement, permet dans certains cas de colorier optimalement le graphe. Nous prouvons une conjecture de Everett et Reed affirmant que cette approche fonctionne pour une classe de graphes parfaits: les graphes d'Artemis. Nous en deduisons un algorithme de coloration des graphes Artemis de complexite O(mn^2). Nous donnons un algorithme de complexite O(n^9) pour la reconnaissance des graphes d'Artemis. D'autres algorithmes de reconnaissance sont donnes, tous fondes sur des routines de detection de sous-graphes dans des graphes de Berge. Nous montrons que ces problemes de detection sont NP-complets si on cherche a les etendre aux graphes quelconques.
Solar neutrino physics with Borexino

We present the most recent solar neutrino results from the Borexino experiment at the Gran Sasso underground laboratory. In particular, refined measurements of all neutrinos produced in the pp fusion chain have been made. It is the first time that the same detector measures the entire range of solar neutrinos at once. These new data weakly favor a high-metallicity Sun. Prospects for measuring CNO solar neutrinos are also discussed.
A Hybrid Convolution Neural Network with Binary Particle Swarm Optimization for Intrusion Detection

—Many companies start using could systems and services to increase their productivity and decrease the cost by migrating their applications, infrastructures, and data to external cloud platforms. Using cloud systems leads to raise the number of attacks on such systems. Protecting these cloud platforms from different attacks becomes an essential task using Intrusion detection systems (IDS). In general, IDS is used to detect normal or abnormal network trafﬁc packets. In this paper, we proposed a hybrid intelligent IDS system based on a one-dimensional Convolution Neural Network (1D-CNN) and Binary Particle swarm Optimization (BPSO). BPSO is employed as a wrapper feature selection to determine the most valuable features and reduce the high dimensionality of collected data. While 1D-CNN is employed as a binary classiﬁer. We adopted a real dataset called UNSW-NB15 to evaluate the proposed hybrid IDS. The obtained results show the proposed system can detect normal and abnormal packets with an accuracy equals 94 . 3% .
Influence of Medical Case History in the Orthodontic Diagnosis and Treatment Planning: A Review

Most significant and often neglected part of diagnosis and treatment planning in orthodontics is medical case history recording. It is significant because it provides information regarding current health status, and its influence on periodontal tissue remodeling. Several diseases which require long term drugs may predispose teeth to iatrogenic root resorption following application of a mechanical stimulus such as application of orthodontic forces. Few situations during case history recording patient hesitate to reveal realistic medical history in presence of some sexually transmitted disease. Main of this paper presentation is to provide comprehensive knowledge regarding rationale behind recording medical case history, also influence of systemic disorders in orthodontic treatment planning.
Institutional Knowledge at Singapore Management University Forecasting Bond Risk Premia Using Technical Analysis

While economic variables have been used extensively to forecast the U.S. bond risk premia, little attention has been paid to the use of technical indicators which are widely employed by practitioners. In this paper, we ﬁll this gap by studying the predictive ability of using a variety of technical indicators vis-´a-vis the economic variables. We ﬁnd that the technical indicators have statistically and economically signiﬁcant in- and out-of-sample forecasting power. More-over, we ﬁnd that utilizing information from both technical indicators and economic variables substantially increases the forecasting performances relative to using just economic variables. Abstract While economic variables have been used extensively to forecast the U.S. bond risk premia, little attention has been paid to the use of technical indicators which are widely employed by practitioners. In this paper, we ﬁll this gap by studying the predictive ability of using a variety of technical indicators vis-´a-vis the economic variables. We ﬁnd that the technical indicators have statistically and economically signiﬁcant in- and out-of-sample forecasting power. More-over, we ﬁnd that utilizing information from both technical indicators and economic variables substantially increases the forecasting performances relative to using just economic variables.
Role of P v-a CO 2 gradient and P v-a CO 2 /C a-v O 2 ratio during Cardiac Surgery

Background. Arterial lactate, mixed venous O 2 saturation and parameters derived from CO 2 metabolism 3 as the venous minus arterial CO 2 partial pressure (P v-a CO 2 ) gradient and the ratio between this gradient 4 and the arterial minus venous oxygen content (P v-a CO 2 /C a-v O 2 ) were proposed as markers of tissue 5 hypoperfusion and oxygenation. The main goals were to characterize their physiologic determinants of P v-a CO 2 difference, and the P v- a CO 2 /C a-v O 2 ratio and the interchangeability of the variables calculated from mixed and central venous samples.