Miracle-dz/UniFAR-FTUs huggingface dataset:
Soluble Tumor Necrosis Factor Receptor 1 is Associated With Cardiovascular Risk in Persons With Coronary Artery Calcium Score of Zero

Background: A coronary artery calcium (CAC) score of zero confers a low but nonzero risk of atherosclerotic cardiovascular events (CVD) in asymptomatic patient populations, and additional risk stratification is needed to guide preventive interventions. Soluble tumor necrosis factor receptors (sTNFR-1 and sTNFR-2) are shed in the context of TNF-alpha signaling and systemic inflammation, which play a role in atherosclerosis and plaque instability. We hypothesized that serum sTNFR-1 concentrations may aid in cardiovascular risk stratification among asymptomatic patients with a CAC score of zero. Methods: We included all participants with CAC=0 and baseline sTNFR-1 measurements from the prospective cohort Multi-Ethnic Study of Atherosclerosis (MESA). The primary outcome was a composite CVD event (myocardial infarction, stroke, coronary revascularization, cardiovascular death). Results: The study included 1471 participants (mean age 57.6 years, 64% female), with measured baseline sTNFR-1 ranging from 603 pg/mL to 5544 pg/mL (mean 1294 pg/mL ±378.8 pg/mL). Over a median follow-up of 8.5 years, 37 participants (2.5%) experienced a CVD event. In multivariable analyses adjusted for Framingham Score, doubling of sTNFR-1 was associated with a 3-fold increase in the hazards of CVD (HR 3.0, 95% CI: 1.48-6.09, P = 0.002), which remained significant after adjusting for traditional CVD risk factors individually (HR 2.29; 95% CI: 1.04-5.06, P=0.04). Doubling of sTNFR-1 was also associated with progression of CAC >100, adjusted for age (OR 2.84, 95% CI: 1.33-6.03, P=0.007). Conclusions: sTNFR-1 concentrations are associated with more CVD events in participants with a CAC score of zero. Utilizing sTNFR-1 measurements may improve cardiovascular risk stratification and guide primary prevention in otherwise low-risk individuals.
Insecticide Resistance in the Brown Planthopper, Nilaparvata lugens (Stål): Mechanisms and Status in Asian Countries

The brown planthopper, Nilaparvata lugens (Stål) is a destructive rice pest found in almost all the rice-growing areas across the globe. In pest management strategies, insecticides are the vital element to control this insect pest. But recently their heavy use poses a risk of control failure because of the development of insecticide resistance. Quick insecticide resistance development nature in N. lugens intrigued scientists to understand the complex resistance mechanism(s), side by side pledge the importance of regular monitoring to know the trend of resistance development. Resistance mechanisms like, target-site insensitivity and enhanced activity of detoxifying enzymes, have been extensively studied and identified in governing the resistance development of N. lugens. Both the field collected and laboratory selected pest populations were tested against commonly used insecticides to detect insecticide resistance ratio. In this review, recent findings of resistance mechanisms, candidate genes those contribute in resistance development have been summarized. We also provide an insight into the metabolic resistance mechanisms that confer significant levels of resistances and the current status of insecticide resistance in N. lugens. This review will help to get a clearer view on present research directions of insecticide resistance in N. lugens.
Guanylyl cyclase‐A phosphorylation decreases cardiac hypertrophy and improves systolic function in male, but not female, mice

Atrial natriuretic peptide (NP) and BNP increase cGMP, which reduces blood pressure and cardiac hypertrophy by activating guanylyl cyclase (GC)‐A, also known as NPR‐A or Npr1. Although GC‐A is highly phosphorylated, and dephosphorylation inactivates the enzyme, the significance of GC‐A phosphorylation to heart structure and function remains unknown. To identify in vivo processes that are regulated by GC‐A phosphorylation, we substituted glutamates for known phosphorylation sites to make GC‐A8E/8E mice that express an enzyme that cannot be inactivated by dephosphorylation. GC‐A activity, but not protein, was increased in heart and kidney membranes from GC‐A8E/8E mice. Activities were threefold higher in female compared to male cardiac ventricles. Plasma cGMP and testosterone were elevated in male and female GC‐A8E/8E mice, but aldosterone was only increased in mutant male mice. Plasma and urinary creatinine concentrations were decreased and increased, respectively, but blood pressure and heart rate were unchanged in male GC‐A8E/8E mice. Heart weight to body weight ratios for GC‐A8E/8E male, but not female, mice were 12% lower with a 14% reduction in cardiomyocyte cross‐sectional area. Subcutaneous injection of fsANP, a long‐lived ANP analog, increased plasma cGMP and decreased aldosterone in male GC‐AWT/WT and GC‐A8E/8E mice at 15 min, but only GC‐A8E/8E mice had elevated levels of plasma cGMP and aldosterone at 60 min. fsANP reduced ventricular ERK1/2 phosphorylation to a greater extent and for a longer time in the male mutant compared to WT mice. Finally, ejection fractions were increased in male but not female hearts from GC‐A8E/8E mice. We conclude that increased phosphorylation‐dependent GC‐A activity decreases cardiac ERK activity, which results in smaller male hearts with improved systolic function.
Combined wavelet transform and regression technique for secondary current compensation of current transformers

A technique is proposed to effectively and efficiently compensate for secondary current of current transformers, particularly in the presence of remanent flux. The technique first utilises the wavelet transform to accurately distinguish the distorted section from the healthy section of a secondary current waveform. Secondly the technique uses the regression method to recover the distorted section making use of features extracted from the healthy section, essentially to restore the secondary current to a scaled down replica of the primary system current. The proposed technique is demonstrated on a sample power system, achieving an average compensation error of 1.5% under varying degrees of saturation caused by different levels of remanent flux.
Live Human Detection Robot in Earthquake Conditions

This report outlines a human searching device that takes the form of a robotic car and serves as a backup mechanism for saving lives in the event of a disaster. The temperature sensor, in general, detects the thermal image of the human body, and there has been extensive research into human searching with the gas and humidity sensor. In the intelligent robot device’s study, achieving accurate and reliable human detection and tracking is a difficult challenge. The architecture of human detection and tracking mechanisms over non-overlapping field of views is examined in this paper. To compensate for their respective flaws, a search method is proposed. The proposed method’s rate and accuracy of human detection was tested in an experimental setting. We may guide the robot’s movement by commanding it to move left, right, forward, or backward. We plan to equip the robot with sensors that will enable us to track and detect humans behind the wall.
ACUTE SYNERGISTIC EFFECTS OF AIR TEMPERATURE, HUMIDITY, AND VELOCITY ON HOMEOSTASIS OF MARKET-SIZE BROILERS

Core body temperature (tb) of market–size male broilers (46 .3 d; 2.8 .0.1 kg; Ross . Ross breed) was continuously measured by telemetry during acute, 90– to 240–min exposures to 18 thermally challenging conditions. The thermal conditions consisted of 18 factorial combinations of three dry–bulb air temperatures (tdb; 35.C, 38.C, and 41.C), two dewpoint temperatures (tdp; 19.4.C and 26.1.C), and three air velocities (V; 0.2, 0.7, and 1.2 m s–1). Based on tb rise after 90–min exposures to the thermal conditions, a temperature–humidity–velocity index (THVI) was developed to delineate the synergistic effects of the thermal components on the birds, having the form of THVI = (0.85tdb + 0.15twb) . V–0.058, where twb = wet–bulb temperature. The homeostasis state of the bird was classified as normal, alert, danger, or emergency, which correspond to a tb rise threshold of 1.0. C, 2.5. C, 4.0. C, or >4.0. C, respectively. These different homeostasis states were functionally and graphically expressed in terms of THVI and exposure time. For example, if the broilers were acutely exposed to a thermal condition for 90 min, then the THVI threshold for the normal, alert, danger, and emergency state would be about 35.C, 38.C, 40.C, and >40.C, respectively. If the exposure duration was increased to 120 min, the THVI threshold would drop to 34.C, 37.C, 38.C, and >38.C, respectively. The results of this study serve as a scientific basis for making management decisions and risk assessment associated with market–size broiler production and handling under thermally challenging conditions.
Optimal Real-Time Pricing-Based Scheduling in Home Energy Management System Using Genetic Algorithms

Smart grids are advanced technologies that have already demonstrated a great potential to maintain balance between the demand and supply of electricity via implementation of demand response (DR). A home energy management system (HEMS) is projected to enable DR applications for residential consumers by monitoring, managing, and controlling their energy consumption. This paper proposes a Genetic Algorithm (GA) based HEMS that reallocates and shifts appliances away from peak consumption periods and high electricity prices in order to minimize the electricity bill and the peak to average ratio (PAR). The HEMS receives electricity prices, which are based on real-time pricing (RTP) scheme, from a smart meter and finds the schedule that minimizes the cost and PAR. Our proposed model categorizes appliances into three categories: 1- shiftable interruptible appliances and 2- shift-able uninterruptible appliances and finally 3- fixed base appliances. A new formulation of the problem, which neglects redundant information and considerably reduces the search space, was developed and tested. The results show a substantial improvement in the scheduling problem compared to the conventional formulation reported in literature. The proposed system was able to effectively reduce the cost by 8.7% and PAR by 29%.
Self-phasing antenna array techniques for mobile communications applications

This paper provides a summary of the basic concepts of retrodirective antenna arrays. Originally this class of antenna was developed in the 1960s for direct satellite-to-ground transmission of high-power microwave energy. The explosive growth of mobile communications has, in the authors' opinion, reopened the debate for alternative applications of retrodirective array techniques. Advances in microstrip antenna design coupled with the availability of integrated circuit amplifier and mixer components permit minimum-complexity retrodirective antenna arrays to be constructed. Several different planar retrodirective antenna architectures are presented and their basic operational characteristics given. A novel application for co-operating retrodirective antennas in a duplex communication link with inherent space division multiple access capability is also described. Finally some of the operational parameters which could ultimately limit the performance of this class of antenna are discussed.
Aminopropylimidazole as an Advantageous Coating in the Synthesis of Functionalized Magnetite Nanoparticles

Implementing new methods to prepare magnetite nanoparticles with a covered or uncovered surface has been, and still is, a significant challenge. In this work, we describe a very clear and effortless way for the preparation of magnetite nanoparticles using two types of bases, namely: 1-(3-aminopropyl)imidazole and sodium hydroxide. Fourier transform infrared spectroscopy (FTIR) served as a tool for the structural investigation of the as-prepared magnetite nanoparticles. The morphology of the samples was investigated using Transmission Electron Microscopy (TEM). Comprehensive high-resolution X-ray photoelectron spectroscopy investigations (XPS) were applied as an effective tool for analyzing the composition of the various types of magnetic nanoparticles. Further polymer linkage was accomplished with poly(benzofuran-co-arylacetic acid) on the amino-functionalized surface of aminopropylimidazole-containing magnetic nanoparticles. The findings are promising for biomedicine, catalysis, and nanotechnology applications.
Existency of two dimensional FIR PR QMF system

Perfect reconstruction (PR) QMF systems have been studied extensively so far because of their application to subband coding, which is a powerful method for compressing speech, image and video data. Multidimensional PR QMF systems are more complicated than one dimensional ones, particularly with regard to the method of decimation. In this paper, we prove various theorems for 2-dimensional QMF systems.
Articulated Models of Cantilevers Conveying Fluid: The Study of a Paradox:

A general theory is presented for the dynamics of nth-degree-of-freedom articulated (lumped flexibility) models of cantilevers conveying fluid, of which the two-degree-of-freedom model of a column subjected to follower forces (first investigated by Ziegler) is a particular case. The ability of the articulated system to predict the dynamical behaviour of the continuous system modelled is investigated, and in particular the paradox that, whereas the continuous system is subject to only oscillatory instability (at sufficiently high flow), the model is generally subject to both oscillatory and buckling instabilities, and sometimes only to the latter. Complex frequency calculations show that buckling is associated with the higher modes of the articulated system, which, irrespective of the number of degrees of freedom, do not model well the corresponding modes of the continuous system. The critical flow velocities for buckling and oscillatory instabilities are calculated extensively, the latter showing good con.
Correlation Evaluation of Pilots' Situation Awareness in Bridge Simulations via Eye-Tracking Technology

To maintain situation awareness (SA) when exposed to emergencies during pilotage, a pilot needs to selectively allocate attentional resources to perceive critical status information about ships and environments. Although it is important to continuously monitor a pilot's SA, its relationship with attention is still not fully understood in ship pilotage. This study performs bridge simulation experiments that include vessel departure, navigation in the fairway, encounters, poor visibility, and anchoring scenes with 13 pilots (mean = 11.3 and standard deviation = 1.4 of experience). Individuals were divided into two SA group levels based on the Situation Awareness Rating Technology (SART-2) score (mean = 20.13 and standard deviation = 5.83) after the experiments. The visual patterns using different SA groups were examined using heat maps and scan paths based on pilots' fixations and saccade data. The preliminary visual analyses of the heat maps and scan paths indicate that the pilots' attentional distribution is modulated by the SA level. That is, the most concerning areas of interest (AOIs) for pilots in the high and low SA groups are outside the window (AOI-2) and electronic charts (AOI-1), respectively. Subsequently, permutation simulations were utilized to identify statistical differences between the pilots' eye-tracking metrics and SA. The results of the statistical analyses show that the fixation and saccade metrics are affected by the SA level in different AOIs across the five scenes, which confirms the findings of previous studies. In encounter scenes, the pilots' SA level is correlated with the fixation and saccade metrics: fixation count (p = 0.034 < 0.05 in AOI-1 and p = 0.032 < 0.05 in AOI-2), fixation duration (p = 0.043 < 0.05 in AOI-1 and p = 0.014 < 0.05 in AOI-2), and saccade count (p = 0.086 < 0.1 in AOI-1 and p = 0.054 < 0.1 in AOI-2). This was determined by the fixation count (p = 0.024 < 0.05 in AOI-1 and p = 0.034 < 0.05 in AOI-2), fixation duration (p = 0.036 < 0.05 in AOI-1 and p = 0.047 < 0.05 in AOI-2), and saccade duration (p = 0.05 ≤ 0.05 in AOI-1 and p = 0.042 < 0.05 in AOI-2) in poor-visibility scenes. In the remaining scenes, the SA could not be measured using eye movements alone. This study lays a foundation for the cognitive mechanism recognition of pilots based on SA via eye-tracking technology, which provides a reference to establish cognitive competency standards in preliminary pilot screenings.
A Comprehensive Review of the Potential Use of Green Tea Polyphenols in the Management of COVID-19

Green tea is produced from Camellia sinensis (L.) buds and leaves that have not gone through the oxidation and withering processes used to produce black and oolong teas. It was originated in China, but its cultivation and production have expanded to other Eastern Asian countries. Several polyphenolic compounds, including flavandiols, flavonols, flavonoids, and phenolic acids, are found in green tea and may constitute greater than 30% of the dry weight. Flavonols, especially catechins, represent the majority of green tea polyphenols. Green tea polyphenolic compounds have been reported to confer several health benefits. This review describes the potential use of green tea polyphenols in the management of coronavirus disease 2019 (COVID-19). The immunomodulatory, antibacterial, antioxidant, and anti-inflammatory effects of green tea polyphenols have also been considered in this review. In addition to describing the bioactivities associated with green tea polyphenols, this review discusses the potential delivery of these biomolecules using a nanoparticle drug delivery system. Moreover, the bioavailability and toxicity of green tea polyphenols are also evaluated.
Indoor ambient light noise and its effect on wireless optical links

Knowledge of ambient optical noise is essential for designers of free space optical links, for designing resilient circuits. An experimental characterisation of the most commonly encountered ambient optical radiation is presented. The study includes tungsten filament sources, low and high frequency fluorescent lights, IR headphones, TV remote controls and daylight. Practical means to reduce their influence on the performance of the links are also given. The results are also valuable for setting a standard way of comparing wireless IR links, based on testing their performance under such ambient noise.
Discourses and Educational Initiatives for Developing Sustainability Competences of the World Business Council for Sustainable Development

Abstract The adoption of the logic of developing sustainable development (SD) competences in the business environment has grown both in the literature in the area and in business initiative programs. One player that emerges with the aim of assuming leadership in this process is the World Business Council for Sustainable Development (WBCSD). This article aims to answer the following research question: Are the WBCSD’s discourses and initiatives for developing sustainability competences spaces of various translations of corporate sustainability or a place for reaffirming logocentric and definitive discourses on the theme? For this, we analyzed the institutional documents (Vision 2050 and Action 2020) and carried out a series of on-site visits at the Brazilian and Portuguese BCSDs. In addition, we conducted a set of in-depth interviews with the managers and participants in the initiatives for developing sustainability competences (DSC). The data were analyzed according to the categories of Derrida’s deconstruction process. The analysis of the educational initiatives of the Brazilian and Portuguese BCSDs showed that they include the various discourses on corporate sustainability in their formative approach; however, logocentric and definitive thinking about the theme is reaffirmed in that the way the Vision 2050 guidelines are carried out is limited to the application of management tools.
Role and Perspectives of Inflammation and C-Reactive Protein (CRP) in Psychosis: An Economic and Widespread Tool for Assessing the Disease

Schizophrenia is a major psychotic disorder affecting nearly 23.6 million people globally and greatly impacting the cognitive and social functioning of individuals. Multiple risk factors, including genetic, environmental, and epigenetic factors have been identified. However, the exact mechanism by which some factors aid in the development of schizophrenia is still uncertain. Acute and/or long-standing inflammation has been implicated as both a cause and effect of schizophrenia. Heightened immune responses have been documented in large cohorts of individuals with schizophrenia. While not completely known, multiple hypotheses, such as disruption of the blood–brain barrier, alterations in the kynurenine/tryptophan pathway, and increased microglial activation, have been presented to correlate inflammation with schizophrenic symptoms. Measurement of C-reactive protein (CRP) is a commonly performed and inexpensive test on patients’ serum to determine levels of systemic inflammation in the body. Multiple studies have reported an elevated CRP level in different stages of schizophrenia, indicating its potential to be used as a viable biomarker in the diagnosis and monitoring of schizophrenia along with assessing treatment response to conventional and non-conventional treatment regimens. This review aims to evaluate the role of inflammation, in general, and CRP, in particular, in the pathogenesis of schizophrenia and its potential significance in diagnostic, therapeutic, and preventative approaches towards schizophrenia and psychosis.
First-Principles Calculations to Investigate the Third-Order Elastic Constants and Mechanical Properties of Mg, Be, Ti, Zn, Zr, and Cd

<jats:p>We present theoretical studies for the third-order elastic constants of Mg, Be, Ti, Zn, Zr, and Cd with a hexagonal-close-packed (HCP) structure. The method of homogeneous deformation combined with first-principles total-energy calculations is employed. The deformation gradient <jats:inline-formula> <math xmlns="http://www.w3. org/1998/Math/MathML" id="M1"> <msub> <mrow> <mi>F</mi> </mrow> <mrow> <mi>i</mi> <mi>j</mi> </mrow> </msub> </math> </jats:inline-formula> is applied to the crystal lattice vectors <jats:inline-formula> <math xmlns="http://www.w3. org/1998/Math/MathML" id="M2"> <msub> <mrow> <mi>r</mi> </mrow> <mrow> <mi>i</mi> </mrow> </msub> </math> </jats:inline-formula>, and the elastic strain energy can be obtained from the first-principles calculation. The second- and third-order elastic constants are extracted by a polynomial fit to the calculated energy-strain results. In order to assure the accuracy of our method, we calculated the complete set of the equilibrium lattice parameters and second-order elastic constants for Mg, Be, Ti, Zn, Zr, and Cd, and our results provide better agreement with the previous calculated and experimental values. Besides, we have calculated the pressure derivatives of SOECs related to third-order elastic constants, and high-pressure effects on elastic anisotropy, ductile-to-brittle criterion, and Vickers hardness are also investigated. The results show that the hardness model <jats:inline-formula> <math xmlns="http://www.w3. org/1998/Math/MathML" id="M3"> <msub> <mrow> <mi>H</mi> </mrow> <mrow> <mi>v</mi> </mrow> </msub> <mo>=</mo> <mn>1.877</mn> <msup> <mrow> <mfenced open="(" close=")" separators="|"> <mrow> <msup> <mrow> <mi>k</mi> </mrow> <mrow> <mn>2</mn> </mrow> </msup> <mi>G</mi> </mrow> </mfenced> </mrow> <mrow> <mn>0.585</mn> </mrow> </msup> </math> </jats:inline-formula> is more appropriate than <jats:inline-formula> <math xmlns="http://www.w3. org/1998/Math/MathML" id="M4"> <msub> <mrow> <mi>H</mi> </mrow> <mrow> <mi>v</mi> </mrow> </msub> <mo>=</mo> <mn>2</mn> <msup> <mrow> <mfenced open="(" close=")" separators="|"> <mrow> <msup> <mrow> <mi>k</mi> </mrow> <mrow> <mn>2</mn> </mrow> </msup> <mi>G</mi> </mrow> </mfenced> </mrow> <mrow> <mn>0.585</mn> </mrow> </msup> <mo>−</mo> <mn>3</mn> </math> </jats:inline-formula> for HCP metals under high pressure. </jats:p>