Miracle-dz/UniFAR-FTUs huggingface dataset:
UNCERTAINTIES IN THE DYNAMIC BEHAVIOUR OF TIMBER FOOTBRIDGES CONSIDERING HUMAN STRUCTURE INTERACTION

A dynamic study of timber footbridges with uncertain mechanical properties considering the Human Structure Interaction (HSI) induced by the pedestrians is presented in this paper. These structural systems made of timber are increasingly employed due to the high stiffness/weight ratio that wood exhibits in relation to others structural materials. More, the development and implementation of laminated beams permits larger spans. These features can lead to lightweight structural systems in which the acceleration levels can exceed the human comfort limits. The sources of uncertainty of this structural model are the timber mechanical and physical properties, Modulus of Elasticity (MOE) and mass density. Also, the geometrical design of the boards that compose the laminated timber beams supporting the ﬂoor involves variability in the distances between ﬁnger joints. Probability Density Functions (PDFs) of the timber properties are formulated from the Principle of Maximum Entropy (PME). The ﬁnger joints distance generates the lengthwise variability of the MOE and mass density functions in each board of the laminated beams. The inﬂuence of these stochastic variables in the structural response on a free vibration problem that includes the HSI induced by the human walking is assessed. Pedestrians arrive to the footbridge under a Poisson distribution and the arrival velocity is such that a medium/low transit density is achieved in accordance with the footbridge dimension. Stochastic properties of the HSI model are introduced through their PDFs. Changes in the natural frequencies and damping of the structure induced by the HSI are numerically obtained through the Finite Element Method (FEM) and Monte Carlo Simulations (MCS). These modiﬁcations are evaluated in relation to the footbridge occupancy at each instant. The present stochastic model contributes to obtain a more realistic description of the response of this type of structures.
Value Stream Mapping in New Product Introduction – A Case Study at Ericsson VIKTOR HEDBERG

Today, companies have to redesign and improve their operational performance to cope with the market competition. While research related to organizational improvements has focused on applications of value stream mapping in mass production plants, it is unclear whether value steam mapping can be applied in new product introduction organizations. This thesis strives to generate and describe a customized value stream mapping tool adapted to manage twofold customer value within new product introduction environments, processes that construct products and information gathered from the production and incorporated into next generation products. The study is conducted with a case study approach including an application of the model in an industrial setting. The findings implicate that the value stream mapping tool is applicable when managing performance improvements during new product introduction. Moreover, performance measures to evaluate the new product introduction information loop are presented. Key-words Value stream mapping, new product introduction, operational performance, customer value
A p-adic integral for the reciprocal of L-functions

We introduce an analog of part of the Langlands-Shahidi method to the p-adic setting, constructing reciprocals of certain p-adic L-functions using the nonconstant terms of the Fourier expansions of Eisenstein series. We carry out the method for the group SL(2), and give explicit p-adic measures whose Mellin transforms are reciprocals of Dirichlet L-functions.
Influence of the malleolar marker position on postural parameters in the sagittal plane

| Photogrammetry is a postural evaluation method that provides information based on the reference of anatomical markers. In the sagittal plane, one of the main evaluations is related to the plumb line; however, the literature shows divergences regarding the placement of the malleolar reference marker. Some argue that it must be placed exactly on the center of the lateral malleolus, while others defend placing it slightly in front of the lateral malleolus. This study aimed to identify whether the modification of the position of the malleolar marker affects the results of the procedure. This is a cross-sectional analytical observational study, with comparative intrasubject design. Forty-four healthy subjects (25 women and 19 men; 27±6 years old; 170±11 cm; 71±15 kg) were evaluated using protocol and software DIPA © for investigation of the variables (plumb line test and pelvic version) in the sagittal plane, with the malleolar marker in two positions: (1) in the center of the lateral malleolus and (2) in front of the lateral malleolus. The analysis was carried out according to descriptive (frequency distribution, mean and standard deviation) and inferential (Shapiro-Wilk test, dependent Student’s t-test, and Wilcoxon test, α =0.05) statistical methods. For both variables, the malleolar marker position presented statistically significant difference (p<0.05) only on the scalar value, not significantly affecting the posture classification. The results suggest that the vertical reference point for photogrammetry, based on the malleolar marker, can be chosen by the evaluator.
Overexpression of Aurora-A bypasses cytokinesis through phosphorylation of SLAN.

Mitosis is a complicated process by which eukaryotic cells segregate duplicated genomes into two daughter cells. To achieve the goal, numerous regulators have been revealed to control mitosis. The oncogenic Aurora-A is a versatile kinase responsible for the regulation of mitosis including chromosome condensation, spindle assembly and centrosome maturation through phosphorylating a range of substrates. However, overexpression of Aurora-A bypasses cytokinesis, thereby generating multiple nuclei without knowing the mechanisms. To explore the underlined mechanisms, we found that SLAN, a potential tumor suppressor, served as a substrate of Aurora-A and knockdown of SLAN induced immature cytokinesis. Aurora-A phosphorylates SLAN at T573 under the help of the scaffold protein 14-3-3ղ. The SLAN phosphorylation mimicking mutants T573D or T573E, in contrast to the phosphorylation deficiency mutant T573A, induced higher level of multinucleated cells, and the endogenous SLAN p573 resided at spindle midzone and midbody with the help of the microtubule motor MKLP1. The Aurora-A- or SLAN-induced multiple nuclei was prevented by the knockdown of 14-3-3ղ or Aurora-A respectively, thereby revealing a 14-3-3ղ/Aurora-A/SLAN cascade negatively controlling cytokinesis. Intriguingly, SLAN T573D or T573E inactivated and T573A activated the key cytokinesis regulator RhoA. RhoA interacted with SLAN np573, i.e. the non-phosphorylated form of SLAN at T573, which localized to the spindle midzone dictated by RhoA and ECT2. Therefore, we report here that SLAN mediates the Aurora-A-triggered cytokinesis bypass, and SLAN plays dual roles in that process depending on its phosphorylation status.
How do you solve a quadratic equation

The nature of the floating-point number system of digital computers is explained to a reader whose university mathematical background is very limited. The possibly large errors in using mathematical algorithms blindly with floating-point computation are illustrated by the formula for solving a quadratic equation. An accurate way of solving a quadratic is outlined. A few general remarks are made about computational mathematics, including the backwards analysis of rounding error.
Post-Activation Potentiation: Is there an Optimal Training Volume and Intensity to Induce Improvements in Vertical Jump Ability in Highly-Trained Subjects?

Abstract The aim of this study was to compare the acute effects of performing half squats (HSs) with different loading intensities (1, 3, and 5 repetitions maximum [RM], and 60% 1RM) and a different number of sets (1, 2, and 3) on the countermovement jump (CMJ) performance of 18 highly-trained male subjects. Participants were submitted to four experimental conditions (1RM, 3RM, 5RM, and 60% 1RM) in randomized order. The CMJ was assessed before and after each set. Differences in CMJ performance between the distinct experimental conditions and individual responses in CMJ performance induced by the different protocols were analyzed via the magnitude-based inference method. Overall, significant improvements were detected in individual CMJ heights after each activation protocol. It can be concluded that the use of 1 to 3 sets of HSs performed at moderate-to-high loads may be an effective strategy to improve jump performance in highly-trained subjects. Nevertheless, despite the high efficiency of the protocols tested here, coaches and researchers are strongly encouraged to perform individualized assessments within the proposed range of loads and sets, to find optimal and tailored post-activation potentiation protocols.
Linear Approximate Groups

This is an informal announcement of results to be described and proved in detail in a paper to appear. We give various results on the structure of approximate subgroups in linear groups such as $\SL_n(k)$. For example, generalising a result of Helfgott (who handled the cases $n = 2$ and 3), we show that any approximate subgroup of $\SL_n(\F_q)$ which generates the group must be either very small or else nearly all of $\SL_n(\F_q)$. The argument is valid for all Chevalley groups $G(\F_q)$.
A nalyzing fish stocks dynamics using CPUE and PRCF : a new approach for the fishery management

C atch per unit effort has been used in many fisheries researches worldwide like an abundance or density index. P arallel to this issue, partial ratio correlation function is a technique used to identify the density dependent structure underlying ecological time series. A lthough partial ratio correlation function is widely used in ecological fields, it has not been much used in fisheries and aquatic sciences. I n this synthesis, a new combination of statistical techniques is proposed to diagnose the order of the population dynamic of fish stocks, as the first knowledge of the type of factors that may be regulating them, included human predation as an exogenous factor.
In-duct and radiation matching strategies : preliminary report : TurboNoiseCFD Workpackage 2, Deliverable D2.3

The matching problem is considered across the interface between a region with CFD-type full Navier-Stokes modelling (the source region) and a region (duct) with an acoustic ﬁeld with mean ﬂow modelling. The discontinuous ﬁeld cannot be avoided. Therefore a method is proposed, based on a modal representation of the acoustic ﬁeld, to determine the ﬁeld as well as possible by means of a least squares modiﬁcation of a Galerkin-type mode matching. acoustic ﬁeld. Abstract In this preliminary report, an approach taken by ISVR on the TurboNoiseCFD project bypass/exhaust duct noise radiation calculation is described. The ISVR model consists of a wave admission region, a computational aeroacoustic (CAA) region and a radiation model based on an integral solution of the Ffowcs Williams-Hawkings (FW-H) equation implemented numerically to allow near- and far-ﬁeld noise levels to be determined efﬁciently. The wave admission region is designed to allow for the matching of incoming acoustic waves with the CAA region. At this stage of the project research, a number of issues need to be addressed so that the model can be validated and used in the TurboNoiseCFD project. only other input required for the LEE solver is the mean ﬂow ﬁeld. In a simple case this can be generated using either an analytic mean ﬂow proﬁle or time-averaged solutions of the Navier-Stokes Equations for the ﬂow within the CAA ﬁeld. The LEE solver uses a 6th-order compact scheme for the spatial derivatives and a 4/6 stage explicit Runge-Kutta scheme for the time integration. The solver outputs the temporal and spatial variations of the unsteady ﬂow perturbations ( (cid:26) 0 ; u 0 ; v 0 ; w 0 ; p 0 ). These act as the input to the Ffowcs-Williams Hawkings solver.
Essential stability in large square economies

Exchange economies are deﬁned by a mapping between an atomless space of agents and a space of characteristics where the commodity space is a separable Banach space. We characterize equilibrium stability of economies relaying on the continuity of the equilibrium correspondence. We provide a positive answer to an open question about the continuity of the Walras correspondence in inﬁnite dimensional spaces. In addition, we do not assume neither diﬀerentiability nor a ﬁxed set of agents for the diﬀerent economies, like it is usually assumed in the stability literature.
FREQUENCY OF IRON DEFICIENCY AND IRON DEFICIENCY ANEMIA IN FIBROMYALGIA SYNDROME FİBROMİYALJİ SENDROMUNDA DEMİR EKSİKLİĞİ VE DEMİR EKSİKLİĞİ ANEMİSİ GÖRÜLME SIKLIĞI

Objective Fibromyalgia syndrome (FMS), which is a chronic pain condition of unknown etiology, is mainly characterized by widespread pain, sleep disturbances, memory problems, and fatigue, which seriously im-pair quality of life. Decreased production of biogenic amine neurotransmitters as a result of decreased iron levels in the blood may play a role in the pathophysiology of FMS. This study aimed to investigate the prevalence of iron-deficiency and iron-deficiency anemia in patients with FMS and to draw attention to the prevalence of iron-deficiency in patients with FMS. retrospectively. Data were analyzed by using SPSS 23 package program.
Absolute connectedness and classical groups

We introduce and develop the model-theoretic notions of absolute connectedness and type-absolute connectedness for groups. We prove that groups of rational points of split semisimple linear groups (that is, Chevalley groups) over arbitrary infinite fields are absolutely connected and characterize connected Lie groups which are type-absolutely connected. We prove that the class of type-absolutely connected group is exactly the class of discretely topologized groups with trivial Bohr compactification, that is the class of minimally almost periodic groups. As an application we generalize some results of Conversano-Pillay and construct a group $G$ where G^{00}/G^{\infty} is far from being abelian.
Never mind the metrics -- what about the uncertainty? Visualising confusion matrix metric distributions

There are strong incentives to build models that demonstrate outstanding predictive performance on various datasets and benchmarks. We believe these incentives risk a narrow focus on models and on the performance metrics used to evaluate and compare them -- resulting in a growing body of literature to evaluate and compare metrics. This paper strives for a more balanced perspective on classifier performance metrics by highlighting their distributions under different models of uncertainty and showing how this uncertainty can easily eclipse differences in the empirical performance of classifiers. We begin by emphasising the fundamentally discrete nature of empirical confusion matrices and show how binary matrices can be meaningfully represented in a three dimensional compositional lattice, whose cross-sections form the basis of the space of receiver operating characteristic (ROC) curves. We develop equations, animations and interactive visualisations of the contours of performance metrics within (and beyond) this ROC space, showing how some are affected by class imbalance. We provide interactive visualisations that show the discrete posterior predictive probability mass functions of true and false positive rates in ROC space, and how these relate to uncertainty in performance metrics such as Balanced Accuracy (BA) and the Matthews Correlation Coefficient (MCC). Our hope is that these insights and visualisations will raise greater awareness of the substantial uncertainty in performance metric estimates that can arise when classifiers are evaluated on empirical datasets and benchmarks, and that classification model performance claims should be tempered by this understanding.
Tagged-MRI Sequence to Audio Synthesis via Self Residual Attention Guided Heterogeneous Translator

Understanding the underlying relationship between tongue and oropharyngeal muscle deformation seen in tagged-MRI and intelligible speech plays an important role in advancing speech motor control theories and treatment of speech related-disorders. Because of their heterogeneous representations, however, direct mapping between the two modalities-i.e., two-dimensional (mid-sagittal slice) plus time tagged-MRI sequence and its corresponding one-dimensional waveform-is not straightforward. Instead, we resort to two-dimensional spectrograms as an intermediate representation, which contains both pitch and resonance, from which to develop an end-to-end deep learning framework to translate from a sequence of tagged-MRI to its corresponding audio waveform with limited dataset size. Our framework is based on a novel fully convolutional asymmetry translator with guidance of a self residual attention strategy to specifically exploit the moving muscular structures during speech. In addition, we leverage a pairwise correlation of the samples with the same utterances with a latent space representation disentanglement strategy. Furthermore, we incorporate an adversarial training approach with generative adversarial networks to offer improved realism on our generated spectrograms. Our experimental results, carried out with a total of 63 tagged-MRI sequences alongside speech acoustics, showed that our framework enabled the generation of clear audio waveforms from a sequence of tagged-MRI, surpassing competing methods. Thus, our framework provides the great potential to help better understand the relationship between the two modalities.
Height Responses in Complete Idiopathic Deficient Children Less Than Three Years during Growth Hormone Therapy Growth of Age

To know the effect of the age factor on growth response to growth hormone (GH) therapy in patients less than three years of age with complete idiopathic growth hormone deficiency (GHD). One hundred thirty-seven prepubertal children with complete idiopathic GHD from the database of the International Growth Cooperative Study (ICGS) of Japan for more than two years were analyzed. The patients were divided into four groups according to age at the start of GH therapy; group 1, s three years, group 2, three to S six years, group 3, six to s nine years, group 4, >nine years. In group 1 the mean birth weight SDS of 0.17 was not the lowest. Patients in group 1 had the lowest HSDS (4.53) at the start of the therapy (P<0.01). During two years of the treatment, the mean HSDS improved from -4 . 53 to -2.15 with an increase in mean SD score of 2.12 in group 1, but in group 4 it was only 0.92 (P<0.01). In group 1, the mean HSDS declined from -0.17 at birth to -4.53 progressively. Delta height SDS during the first year of treatment in Group 1 was 1.59 SD, which is the highest. The decrease in %overweight during the first year showed that in group 1, the reduction in adiposity was the greatest among the groups (P<0.05). Our data showed that in children with complete GHD less than three years of age, there was severe growth failure, and the onset was not in the prenatal period, but in the postnatal period. Early detection of GHD and therapy with GH is important because normalization of height may be achieved earlier than in older age groups.
Running title:DIETARY LYCOPENE IN QUAIL NUTRITION Academy Section: BIOLOGICAL SCIENCES

This study investigated the impact of supplementing normal and high-fat diets with graded levels of lycopene on the growth performance, cholesterol level of the muscle, and antioxidant markers in Japanese quail. A total of 192, 14 day-old unsexed Japanese quail were part of a 2 x 4 factorial arrangement consisting of a control group; birds that were fed a normal fat diet (NFD), another control group; birds that were fed a high-fat diet (HFD) with four levels of lycopene for NFD and HFD (0, 100, 200 and 300mg lycopene/kg diet). Lycopene level of 300mg/kg gave the greatest body weight, body weight gain, and relative growth rate when added to the NFD, but this level showed non-signifi cant improvement in growth performance when supplemented to an HFD. Superoxide dismutase in the muscle and liver was noted to be high in NFD+ 300mgL, HFD+ 200mgL, and HFD+ 300mgL groups, while malondialdehyde level in the muscle and liver and cholesterol level in the muscle was found to be low in the same groups. Lycopene slightly improved growth performance, but signifi cantly improved the antioxidant status and lowered cholesterol concentration in the muscle. A diet supplemented with 300 mg lycopene/kg could be recommended for Japanese quail.
Chapter 15. Inherited Conduction Disease and Atrial Fibrillation

Research efforts have focused on two approaches – examining genetic variants in the human population, and then investigating expression of specific genes in animal models or human tissue. Genetics in the human may involve analysis of AF/conduction disease as a monogenic disease in individuals with primary electrical disease, analysis of AF/conduction disease presenting in the setting of another familial disease, or the genetic background that might predispose to the disease without it necessarily segregating in a family. The first two pathways provide definitive insight into the aetiology and require analysis of families with the disease segregating across generations and following Mendelian inheritance in the context of a large effect size.
The Effect of Genetic Factors on the Submicroscopic Structure of Soybean Chloroplasts

Comparative studies of the differentiation of normal chloroplasts and of the chlorophyll-deficient chloroplasts in mutants of barley (Wettstein 1957) and of oat (Maruyama 1960) have shown that different gene mutants may affect chloroplast differentiation in different ways. Thus, the yellow-green plastids of one barley mutant never reach full development: they exhibit lamellae but no grana, while in the white barley mutant not even lamellae are formed (Wettstein 1957). In albino oats, on the other hand, grana may develop, but plastid differentiation stops at some later stage. Other oat mutants show either lamellar destruction or irregular arrangement of the grana. It would be of interest to extend the investigation to other plants and their mutants. The present paper deals with the situation in the soybean (Glycine max (L.) Merill). In this plant Weber and Weiss (1959) segregated a recessive gene called y11 which affects the development of chlorophyll. In the heterozygous condition this gene results in a light green color of the seedlings, while in the homozygous state it is a yellow lethal: the yellow plants die as soon as the cotyledonary reserves are exhausted. The y11 gene showed up in a soybean plant of the F3 generation from a cross between Richland and Linman 533. The leaves on the main axis and branches at nodes three through seven had yellow chimeric sectors. All leaves below the third and above the seventh nodes were normal green, and normal green plants resulted from seed borne at these nodes. Plants from seed produced at the nodes bearing sectored leaves segregated as follows: 1 Y11Y11 (normal green): 2 Y11y11 (light green): 1 y11y11 (yellow lethal). No chimeric sectors were observed in subsequent generations. A monogenetic basis was thus established.