Miracle-dz/UniFAR-FTUs huggingface dataset:
Can we improve the representation of modelled ocean mixed-layer by assimilating surface-only satellite-derived data? A case study for the tropical Pacific during the 1997-98 El Nino

HAL is a multi-disciplinary open access archive for the deposit and dissemination of scientific research documents, whether they are published or not. The documents may come from teaching and research institutions in France or abroad, or from public or private research centers. L’archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d’enseignement et de recherche français ou étrangers, des laboratoires publics ou privés. Can we improve the representation of modelled ocean mixed-layer by assimilating surface-only satellite-derived data ? A case study for the tropical Pacific during the 1997-98 El Nino Fabien Durand, Lionel Gourdeau, Jacques Verron, Thierry Delcroix
Proinflammatory Cytokines Production Influencing Th17 Differentiation and Severity of Rheumatoid Arthritis by A Microbial Polysaccharide Reduces the

Rheumatoid arthritis (RA) is a chronic and debilitating autoimmune disease characterized by chronic joint inﬂammation with subsequent cartilage and bone destruction. RA is emerging as a model of IL-17-driven autoimmune inﬂammatory disease. IL-17 is a marker for Th17 cells, with its master regulator being the retinoic acid receptor-related orphan receptor (ROR (cid:1) t) regulated by STAT3 signaling. Glucuronoxylomannan (GXM), a polysaccharide representing the main component of the capsular material of the opportunistic yeast Cryptococcus neoformans , exhibits potent immunosuppressive properties both in vitro and in vivo. The present study investigates the effects of GXM treatment on the progression of collagen-induced arthritis. GXM suppressed clinical signs of collagen-induced arthritis and blocked joint erosion progression. This effect was mediated by down-regulation of key cytokines involved in the pathogenesis of RA such as TNF- (cid:2) and IL-1 (cid:3) , and up-regulation of the inhibitory cytokine IL-10. Moreover, a reduction of IL-6 and TGF- (cid:3) , which inhibit Th17 differentiation with consequent decreased IL-17 production at the local and systemic level, was observed. The effect of GXM on Th17 differentiation mirrored the reduction in STAT3 activation and inhibition of ROR (cid:1) t synthesis. Consequently, this work highlights the beneﬁcial properties of an efﬁcacious compound that could eventually be destined to the clinic. The Journal of Immunology, 2009, 183: 191–200.
ON CHIP MEASUREMENT OF IC(VBE) CHARACTERISTICS FOR HIGH ACCURACY BANDGAP APPLICATIONS

The EG and Xrl coefficients are sufficient to completely characterise the temperature dependence of lc(VBE) relationship of bipolar transistors (BJT). They are usually obtained from measured VSE(T) values, using least square algorithm at a constant collector current. This method involves an accurate measurement of VBE and of the operating temperature. We propose in this paper, a configurable test structure dedicated to the extraction of the temperature dependence of Ic(VBE) characteristic for the BJT designed with bipolar or BiCMOS processes. This allows a direct measurement of the die temperature and consequently an accurate measurement of VB~(T). First, the classical extraction method is explained. Then, the implementation technique of the new method is discussed and finally, an improvement of a bandgap design is presented. I. INTRODUCTION UE to the considerable expansion of portable D applications like cellular telephone, PALM, electronic organiser and others, great interest is given to design methodologies for low consumption. As a consequence, we observe a continuous decrease of the values of the bias current and the supply voltage used in mixed integrated applications. Due to their very low consumption and their wide temperature range of operation, bandgap references are widely used in various types of analog circuits for signal processing such as A/D and D/A converters, voltage regulators and a number of measurement devices. Designing high stability circuits such as the bandgap references demands to obtain a very good correlation between the physical parameters and their representation model used in the electrical simulators. Characterising these parameters for low voltage and current operating points over a wide range of temperature is out of the current foundry measurement protocols. At low operating bias conditions parasitic effects are exhausted, this greatly modifies the stability conditions at high temperature of critical designs such as bandgap references. This stability may be deduced from the BJT's saturation current equation commonly used in electrical simulators (I) where q is the electron charge, k is the Boltzman constant and EG is the forbidden energy band value at 0 K of silicon including the band gap narrowing. XTI is a constant parameter, related to the temperature dependence of the mobility of minority carriers in the base region and To is the reference temperature. EG and XT, are among the most difficult parameter
The effects of multiple firefighting activities on information processing and work performance in a smoke‐diving room: An intervention study

Firefighters perform various tasks during firefighting operations under unknown and unpredictable conditions. The present study investigated the impact of firefighting activities and cooling tactics on information processing and work performance. Firefighters performed typical firefighting tasks in the four experimental conditions, namely i) no cooling device (NC), ii) cooling gel (CG), iii) cool vest (CV), and iv) cooling gel and cool vest (CG + CV). The measurement of information processing, Paced Auditory Serial Addition Test (PASAT) scores decreased significantly after the firefighting activities in the four conditions, relative to baseline. The results revealed no significant difference in PASAT scores among the four conditions. However, the performance time (PT) was significantly shorter for the CV and CG + CV compared to the NC and CG conditions. The findings confirmed that the firefighting activities have a detrimental effect on information processing. The CG + CV and CV were more effective than CG and NC in improving PT during firefighting. However, the cooling strategies have a negligible effect on improving information processing performance.
Neural Network-Based Reasoning for Solving the Tower of Hanoi

—In this paper, we propose a reasoning solution, which can infer the rules of game, such as Tower of Hanoi. Neural networks require large amounts of data to improve performance. However, human intelligence requires only a simple exposition. The goal of this paper is to learn to solve a Tower of Hanoi without much learning. We collect sequential data from participants’ experiments that are supposed to solve the Tower of Hanoi. And then, we observe relations between different objects and their actions to establish our reasoning model. We train our reasoning model to solve the Tower of Hanoi. Finally, we show that our reasoning model can infer the rule of game through observations from objects, their relationships and actions.
Understanding the management of personal records at home: a virtual guided tour

Introduction. This paper considers how we can better manage personal records in the home by addressing questions such as how and why personal records are retained in an electronic form and how they are managed. Method. A qualitative method with semi-structured interviews was used. Participants were recruited through social media. The interviews included virtual guided tours of personal records. There were thirty participants in twenty-two interviews (some interviews were with couples). Analysis. Each stage of the personal records management process described by participants was observed and categorised, resulting in an inclusive flow diagram. Results. The management of personal records at home can be categorised and described in terms of a flow. Some commonalities were found between personal information management in the workplace and at home, such as the frequent use of e-mail to manage records and the use of micro-notes and reminders. Conclusion. Personal records management at home can be described as a flow through which records progress. The fact that the study of personal information management has rarely addressed personal information management at home offers many opportunities for fruitful future research.
Medicinal Herbs in the Relief of Neurological, Cardiovascular, and Respiratory Symptoms after COVID-19 Infection A Literature Review

COVID-19 infection causes complications, even in people who have had a mild course of the disease. The most dangerous seem to be neurological ailments: anxiety, depression, mixed anxiety–depressive (MAD) syndromes, and irreversible dementia. These conditions can negatively affect the respiratory system, circulatory system, and heart functioning. We believe that phytotherapy can be helpful in all of these conditions. Clinical trials confirm this possibility. The work presents plant materials (Valeriana officinalis, Melissa officinalis, Passiflora incarnata, Piper methysticum, Humulus lupulus, Ballota nigra, Hypericum perforatum, Rhodiola rosea, Lavandula officinalis, Paullinia cupana, Ginkgo biloba, Murraya koenigii, Crataegus monogyna and oxyacantha, Hedera helix, Polygala senega, Pelargonium sidoides, Lichen islandicus, Plantago lanceolata) and their dominant compounds (valeranon, valtrate, apigenin, citronellal, isovitexin, isoorientin, methysticin, humulone, farnesene, acteoside, hypericin, hyperforin, biapigenin, rosavidin, salidroside, linalool acetate, linalool, caffeine, ginkgolide, bilobalide, mihanimbine, epicatechin, hederacoside C,α-hederine, presegenin, umckalin, 6,7,8-trixydroxybenzopyranone disulfate, fumaroprotocetric acid, protolichesteric acid, aucubin, acteoside) responsible for their activity. It also shows the possibility of reducing post-COVID-19 neurological, respiratory, and cardiovascular complications, which can affect the functioning of the nervous system.
Assessing Tic Disorders in Children with ADHD from a Nationally Representative Sample

Successful treatments exist for both ADHD and tics, but minimal research has been done on treatments that treat tics in children with ADHD. The purpose of this study was to analyze data from a nationally-representative sample of children with ADHD to determine characteristics and demographic factors that maximize tic prevalence and find the most beneficial treatments for those with tics. The data used was from the 2014 National Survey of the Diagnosis and Treatment of ADHD and Tourette Syndrome, a follow-up to the National Survey of Children’s Health, conducted by the CDC. The focus of data analysis was to assess tic prevalence in children with ADHD and different demographic characteristics as well as treatment prevalence among demographics and their effects on children with tic disorders. Males seven years or younger and in families at or below the federal poverty level were most likely to have tics. Rates of tic decline were highest in older children and children in families with income substantially above the poverty line. Antipsychotic medications, peer intervention and dietary supplements were found to be significantly more beneficial to school performance of children with ADHD and tic disorders than children without tics. Based on the sample, a combination of antipsychotics, peer intervention and dietary supplements is likely the best option for children with ADHD and tics. Future clinical studies should prioritize treating comorbid disorders before the perceived primary disorder. Comorbid disorders are often the root cause of problems that can exacerbate symptoms and require intense treatment and care.
Critical incidents of partnership: Exploring context, process and outcomes at NatBank

Despite a rich partnership literature in the UK, relatively little is known about the processes of decision making under partnership regimes. This study examines the first five years of a high profile agreement in a British retail bank. Inspired by critical incident technique, this article explores the way key issues such as globalisation, offshoring and work organisation are handled, and decisions are made. It is argued that one cannot fully understand the outcomes without exploring both the context and process in detail. Benefits for management, unions and employees are also explored, and some of the main challenges to partnership considered. The article suggests that partnership requires a clear understanding of the purpose and the rules of engagement, and highlights a possible gulf between academic and actor expectations. It also highlights the importance of exploring the partnership processes and reveals evidence of the dialogue exerting a moderating effect over decision making, with management, union and employee actors all in favour of the collaborative partnership approach.
Development of β-Cyclodextrin/Konjac-Based Emulsion Gel for a Pork Backfat Substitute in Emulsion-Type Sausage

Emulsion gel has been used to replace animal fats in meat products. Konjac is a widely used gelling agent; however, its low emulsion stability limits its use in meat products. This study aimed to examine the quality characteristics of β-cyclodextrin (CD)-supplemented konjac-based emulsion gel (KEG) (CD-KEG) and its application as a fat substitute in emulsion-type sausages. The supplementation of CD increased hydrogen bonds and hydrophobic interactions with konjac and oil in the gels, respectively. Additionally, CD increased the structural complexity and strength of KEG. Since adding more than 6% of CD to KEG did not increase the gel strength, 6% CD-added KEG was adopted to substitute for pork backfat in manufacturing low-fat emulsion-type sausages. The following formulations of the sausages were prepared: pork backfat 20% (PF20); pork backfat 10% + KEG 10% (KEG10); KEG 20% (KEG20); pork backfat 10% + CD-KEG 10% (CD-KEG10); CD-KEG 20% (CD-KEG20); and pork backfat 5% (PF5). The CD-KEG20 formulation exhibited higher viscosity and viscoelasticity than KEG20, which suggested that CD improves the rheological properties and the thermal stability of meat batter. Additionally, CD-KEG20 showed similar emulsion stability, cooking yield and texture parameters compared with PF20. Therefore, 6% CD-added KEG is a suitable fat substitute for preparing low-fat emulsion-type sausages.
Energy-Aware SYstem-on-chip design of the HIPERLAN/2 standard

This deliverable presents several methodologies and preliminary experimental results regarding the design of low-power memory subsystems. The existing literature is first reviewed in order to identify the class of memory design approaches that are most suitable to the EASY project, namely, those which are applicable in the context of the HIPERLAN/2 SoC development and, at the same time, are general enough to guarantee the implementation of a general-purpose memory design prototype tool. A memory partitioning algorithm is then described in details, together with enhancement techniques that make its use more effective. Preliminary experimental results, collected on some benchmarks, show the usability of the proposed strategy. Copyright  2002 ICOM POLITO UP FhG IIS-A STM IMEC AUTH IST-2000-30093 Low-power memory partitioning and buffering techniques EASY/WP3/POLITO/DL/P/D16/B1 Public 2 History Date Version Comments August 21, 2002 1 First draft, survey section only August 28, 2002 2 Added methodology section August 30, 2002 3 Added partitioning results September 10, 2002 4 Added address clustering section September 13, 2002 5 Version submitted to consortium September 18, 2002 6 Project Approved IST-2000-30093 Low-power memory partitioning and buffering techniques EASY/WP3/POLITO/DL/P/D16/B1 Public 3 Table of contents LIST OF TABLES AND FIGURES.4
Brachymetatarsia: A Classification for Surgical Treatment.

Brachymetatarsia is a congenital osseous and soft tissue deformity of a ray(s) of the foot. Because there is no particular consensus of methodology of lengthening for brachymetatarsia, the authors introduce a comprehensive anatomic classification and a surgical guide to treatment of each classification type. This classification combines the number of the metatarsal(s) affected and the letter(s) indicating the type of brachymetatarsia deformity (A = axial deficiency of the metatarsal, B = bowing of the metatarsal, C = congruency of metatarsal phalangeal joint). This study reviewed of 300 brachymetatarsals in 166 patients. Fifty of the 166 (30%) patients had bilateral brachymetatarsia. Of the 300 metatarsals with brachymetatarsia, 64 (21%) were first metatarsals, 22 (7%) were second metatarsals, 28 (9%) were third metatarsals, 12 (4%) were fifth metatarsals, and 174 (58%) were fourth metatarsals. Classification types that were found was a total of 165 (55%) type A, a total of 6 (2%) type B, a total of 72 (24%) type AB, a total of 39 (13%) type AC, and a total of 18 (6%) type ABC. A total of 16 (10%) male and 150 (90%) female patients were evaluated. The mean preoperative amount of shortening of the metatarsal was 15 mm (range, 4-20 mm), as determined by the preoperative metatarsal parabola deficiency, equating to 30% of the preoperative metatarsal length. Brachymetatarsia is a complex congenital deformity which until now has not been critically analyzed. This study outlines a comprehensive brachymetatarsia classification system which provides an accurate diagnosis of the deformity and offers a surgical treatment algorithm.
Numerical Solutions of Laminar Incompressible Flow Past Parabolic Bodies at Angles of Attack

Numerical solutions of a two-dimensional steady laminar incompressible flow over semi-infinite parabolic bodies at angles of attack are obtained. All solutions are found by using a modified numerical approach to solve the timedependent Navier‐Stokes equations. The governing equations are written for the stream function and vorticity variables and are solved on a nonuniform body-fitted parabolic grid. A check of our solutions to those that exist in the literature at zero angle of attack showed excellent agreement. In addition, at zero angle of attack far from the leading edge, an expected correspondence to Blasius flow was found. At positive angles of attack, the body became aerodynamically loaded with lower pressures on its upper surface. At large enough angles of attack, the flow separated on the upper surface. In all of the cases examined, the flow separation was followed by a reattachment that defined a separation zone. An almost linear increase in the streamwise extent of the separation zone occurred with increasing angle of attack. The separation location and extent of the separation zone was a function of the nose Reynolds number. The results indicated that the shape factor could be used to provide a criterion for separation and reattachment in these cases. The characteristics of the separation zone for this geometry should prove to be an excellent basic flow to document the effect of leading-edge flow separation on acoustic receptivity of boundary-layer instabilities.
Assimilation and Osmoregulation in GOGAT (Glutamate Synthase)-Deficient Mutants of Escherichia coli

An osmosensitive mutant of Escherichia coli was isolated and shown to harbor two mutations that were together necessary for osmosensitivity. One (ossB) was an insertion mutation in the gltBD operon, which encodes the enzyme glutamate synthase (GOGAT), involved in ammonia assimilation and L-glutamate biosynthesis. The other (ossA) was in the fnr gene, encoding the regulator protein FNR for anaerobic gene expression. Several missense or deletion mutations in fnr and gltBD behaved like ossA and ossB, respectively, in conferring osmosensitivity. A mutation affecting the DNA-binding domain of FNR was recessive to fnr with respect to the osmotolerance phenotype but was dominant-negative for its effect on expression of genes in anaerobic respiration. Our results may most simply be interpreted as suggesting the requirement for monomeric FNR during aerobic growth of E. coli in high-osmolarity media, presumably for L-glutamate accumulation via the GOGAT-independent pathway (catalyzed by glutamate dehydrogenase [GDH]), but the mechanism of FNR action is not known. We also found that the spoT gene (encoding guanosine 3*,5*-bispyrophosphate [ppGpp] synthetase II/ppGpp-3* pyrophosphohydrolase), in multiple copies, overcomes the defect in NH4 1
Proposal of a Null Subcarrier Allocation Method for CAZAC-OFDM Systems

— A major drawback of Orthogonal Frequency Division Multiplexing (OFDM) signals is the extremely high Peak-to-Average Power Ratio (PAPR). Constant Amplitude Zero Auto Correlation (CAZAC) precoding can dramatically improve the PAPR of OFDM signals, i.e., up to the same PAPR value of single carrier signals with the same modulation scheme. One negative point of the CAZAC precoding technic is not being able to meet the current wireless standards, which usually require a null subcarrier allocated on the center of data subcarriers. In this paper, we demonstrate the CAZAC-OFDM which completely satisfies the 4G-LTE standard by using the proposed allocation method for a null subcarrier without degrading the PAPR and the Bit-Error-Rate.
COMPARISON OF CARDIOVASCULAR DISEASE RISK ASSOCIATED WITH THE USE OF IMPLANON AND JADELLE CONTRACEPTIVES IMPLANTS AT A TERTIARY HEALTH INSTITUTION OF NORTH WESTERN NIGERIA

Background: Cardiovascular diseases are the leading cause of adult mortality. Abnormal lipid profiles have been associated with a major risk factor for cardiovascular disease (CVD) which is one of the most dominant causes of death in the world. Dyslipidemia contributes to the development of arthrosclerosis. Objectives: The purpose of this study is to determine baseline Castelli index in women who use Implanon and those who use Jadelle contraceptive implants. Compare the extent of cardiovascular atherosclerotic risk associated with the lipid metabolism in women using Implanon and Jadelle subdermal implants over 3 and 6 month of use and evaluate changes in Castelli 1 and 2 indices over 3 and 6 months of use in each group. Methodology: This was a prospective study of clients who desired contraception and chose any of the two subdermal implants (Implanon and Jadelle) as the method of contraception from 1st November 2015 to 30th June 2016. Venous blood samples (fasting) were taken before insertion of the implant (baseline) and at third and sixth month of insertion from each participant. The serum was analysed for lipid profile. Castelli indices I & II were calculated to determine the CVD risk. All the results were entered in to SPSS version 20 and analysed. Results: A total of 100 clients were enrolled for this study. Eightyseven clients completed the study, 42 for Implanon and 45 for Jadelle with an overall response rate of 87%. The baseline Castelli1 indices were 4.1 mg/dl ±1.0 and 3.8 mg/dl ±0.9, Castelli2 indices were 2.6. 1 mg/dl ±1.0 and 2.4 mg/dl ±0.8 for Implanon and Jadelle respectively. These values did not change to a statistically significant level over 3 and 6 months of use when compared between the two implants except in the value of castelli 2 index at 6 month of use p = 0.038. There was statistically significant increase in Castelli 2 index among the Jadelle group at 3 month of use and also at sixth month when compared with baseline ( p<0.05). The other indices were not statistically significant (p>0.05). Conclusion: The cardiovascular risk associated with the use of Implanon and Jadelle appears low, however clients on long term contraceptive implants may require close monitoring of serum lipid profile to checkmate possible occurance of cardiovascular disease risk.