Miracle-dz/UniFAR-FTUs huggingface dataset:
Reconfigurable origami silencers for tunable and programmable sound attenuation

Recent research has discovered that origami-inspired structures possess great versatility in properties and functionalities. In this research, through an integration of origami geometry and duct acoustics, we reveal that the folding-induced shape reconfiguration of a modular origami silencer could yield great tunability and programmability in sound attenuation. This has been made possible through exploring the kinematics of the folding and the extensibility of the modular origami. Numerical and experimental results indicate that by reconfiguring the silencer via a single degree-of-freedom folding mechanism, the sound attenuation bandwidth can be effectively tuned. Meanwhile, based on a comprehensive understanding on the correlations between the origami geometries and the acoustic characteristics, we exemplify that, by incorporating multiple origami layers in a silencer and by programming their geometries, on-demand sound control can be achieved, e.g., attenuation in the prescribed frequency bands, improved attenuation levels, and broadband attenuations. This proof-of-concept study shows that the proposed folding-based mechanism, along with the modularization design concept, would provide a new way to reconfigure the silencer for acoustic adaptability and inspire new innovation in designing acoustic devices.
A Dual-Frequency WPT Based on Multilayer Self-Decoupled Compact Coil and Dual CLCL Hybrid Compensation Topology

This article proposes a dual-frequency wireless power transfer (WPT) with dual CLCL hybrid compensation topology and multilayer self-decoupled compact coils (MLSDCCs). It extends the transmission distance corresponding to stable high transmission power and efficiency. Based on the parameter constraints of compensation capacitances and inductances, CLCL hybrid compensation topology realizes simultaneous resonance at fundamental and third harmonic frequencies. A typical inverter can meet the requirements of dual-frequency WPT without complex control or more number and improve the utilization rate of square voltage. According to interleaving and rotary stacking of unipolar and bipolar coils in MLSDCCs, the couplings between layers and unnecessary couplings of magnetic coupling mechanism (MCM) are eliminated. Only the main couplings for power transmission are retained and the volume of MCM is reduced. Finally, a 1 kW experimental platform is built. Compared with the typical single-frequency WPT, the maximum transmission power is increased by 2.8%, while the maximum transmission efficiency is only reduced by 0.53%. The main advantage is that the transmission distance corresponding to continuous high-power transmission (in the range of 95%–100% maximum receiving power) is increased by 2.75 times. When the lateral offset distance of the Y-axis is one-sixth of the coil side length, the transmission efficiency decreases by only 1.47%.
Modified Cross-Entropy Method for Classification of Events in NILM Systems

Non-intrusive load monitoring is an algorithm or process that disaggregates the total power in a facility to identify consumption of individual appliances. In this paper, a new algorithm is proposed to classify events of appliance states based on modification of the cross-entropy (CE) method. The main contribution is a formulation and solution of the problem with the CE method as a constrained optimization problem. This new technique is called the modified CE method. The proposed algorithm is simple, as it operates in real time, using low rate sampling of the active power. In addition, there is no need to train the system or to use complex hardware. The algorithm is tested using the REDD and AMPds datasets and the results are compared to several state-of-the-art techniques.
Experimental study of matrix permeability of gas shale: An application to CO2-based shale fracturing

Because the limitations of water-based fracturing fluids restrict their fracturing efficiency and scope of application, liquid CO2 is regarded as a promising substitute, owing to its unique characteristics, including its greater environmental friendliness, shorter clean-up time, greater adsorption capacity than CH4 and less formation damage. Conversely, the disadvantage of high leak-off rate of CO2 fracturing due to its very low viscosity determines its applicability in gas shales with ultra-low permeability, accurate measurement of shale permeability to CO2 is therefore crucial to evaluate the appropriate injection rate and total consumption of CO2. The main purpose of this study is to accurately measure shale permeability to CO2 flow during hydraulic fracturing, and to compare the leak-off of CO2 and water fracturing. A series of permeability tests was conducted on cylindrical shale samples 38 mm in diameter and 19 mm long using water, CO2 in different phases and N2 considering multiple influencing factors. According to the experimental results, the apparent permeability of shale matrix to gaseous CO2 or N2 is greatly over-estimated compared with intrinsic permeability or that of liquid CO2 due to the Klinkenberg effect. This phenomenon explains that the permeability values measured under steady-state conditions are much higher than those under transient conditions. Supercritical CO2 with higher molecular kinetic energy has slightly higher permeability than liquid CO2. The leak-off rate of CO2 is an order of magnitude higher than that of water under the same injection conditions due to its lower viscosity. The significant decrease of shale permeability to gas after water flooding is due to the water block effect, and much longer clean-up time and deep water imbibition depth greatly impede the gas transport from the shale matrix to the created fractures. Therefore, it is necessary to substitute water-based fracturing fluids with liquid or super-critical CO2 in clay-abundant shale formations.
On the design of planar antenna using Fibonacci word fractal geometry in support of public safety

In this article, a planar antenna based on Fibonacci word fractal geometry with defected ground structure (DGS) has been investigated. A novel type of antenna radiator is proposed using Fibonacci word fractal which works for public safety and dedicated short range public safety applications. Size of proposed antenna is 50 × 44 mm and it resonates at 4.9 and 5.9 GHz having bandwidth ranging from 4.8 to 5.1 GHz and 5.8 to 6.8 GHz, respectively. Defected Ground Structure is used to improve gain for lower frequency band. Representative results of fractal patch antenna are reported to access the effectiveness of the developed approach in public safety applications. Simulation and experimental result confirms the efficiency of Whale Optimization Algorithm for antenna design. Experimentally measured results are matches well with simulated results and quite promising.
Oxidative Stress Parameters as Biomarkers of Cardiovascular Disease towards the Development and Progression

Cardiovascular disease (CVD) remains the leading cause of death globally, with unhealthy lifestyles today greatly increasing the risk. Over the decades, scientific investigation has been carried out on reactive oxygen species (ROS) and their resultant oxidative stress based on their changes made on biological targets such as lipids, proteins, and DNA. Since the existing clinical studies with antioxidants failed to provide relevant findings on CVD prediction, the focus has shifted towards recognition of oxidised targets as biomarkers to predict prognosis and response to accurate treatment. The identification of redox markers could help clinicians in providing risk stratification for CVD events beyond the traditional prognostic and diagnostic targets. This review will focus on how oxidant-related parameters can be applied as biomarkers for CVD based on recent clinical evidence.
A Metabolomic Profiling of Intra-Uterine Growth Restriction in Placenta and Cord Blood Points to an Impairment of Lipid and Energetic Metabolism

(1) Background: Intrauterine growth restriction (IUGR) involves metabolic changes that may be responsible for an increased risk of metabolic and cardiovascular diseases in adulthood. Several metabolomic profiles have been reported in maternal blood and urine, amniotic fluid, cord blood and newborn urine, but the placenta has been poorly studied so far. (2) Methods: To decipher the origin of this metabolic reprogramming, we conducted a targeted metabolomics study replicated in two cohorts of placenta and one cohort of cord blood by measuring 188 metabolites by mass spectrometry. (3) Results: OPLS-DA multivariate analyses enabled clear discriminations between IUGR and controls, with good predictive capabilities and low overfitting in the two placental cohorts and in cord blood. A signature of 25 discriminating metabolites shared by both placental cohorts was identified. This signature points to sharp impairment of lipid and mitochondrial metabolism with an increased reliance on the creatine-phosphocreatine system by IUGR placentas. Increased placental insulin resistance and significant alteration of fatty acids oxidation, together with relatively higher phospholipase activity in IUGR placentas, were also highlighted. (4) Conclusions: Our results show a deep lipid and energetic remodeling in IUGR placentas that may have a lasting effect on the fetal metabolism.
Online Assortment and Market Segmentation under Bertrand Competition with Set-Dependent Revenues

We consider an online assortment problem with $[n]:=\{1,2,\ldots,n\}$ sellers, each holding exactly one item $i\in[n]$ with initial inventory $c_i\in \mathbb{Z}_+$, and a sequence of homogeneous buyers arriving over a finite time horizon $t=1,2,\ldots,m$. There is an online platform whose goal is to offer a subset $S_t\subseteq [n]$ of sellers to the arriving buyer at time $t$ to maximize the expected revenue derived over the entire horizon while respecting the inventory constraints. Given an assortment $S_t$ at time $t$, it is assumed that the buyer will select an item from $S_t$ based on the well-known multinomial logit model, a well-justified choice model from the economic literature. In this model, the revenue obtained from selling an item $i$ at a given time $t$ critically depends on the assortment $S_t$ offered at that time and is given by the Nash equilibrium of a Bertrand game among the sellers in $S_t$. This imposes a strong dependence/externality among the offered assortments, items revenues, and inventory levels. Despite that challenge, we devise a constant competitive algorithm for the online assortment problem with homogeneous buyers. We also show that the online assortment problem with heterogeneous buyers does not admit a constant competitive algorithm. To compensate for that issue, we then consider the assortment problem under an offline setting with heterogeneous buyers. Under a mild market consistency assumption, we show that the generalized Bertrand game admits a pure Nash equilibrium over general buyer-seller bipartite graphs. Finally, we develop an $O(\ln m)$-approximation algorithm for optimal market segmentation of the generalized Bertrand game which allows the platform to derive higher revenues by partitioning the market into smaller pools.
Sext‐band bandpass filter with compactness based on cascading stage of SIRs

Utilizing cascading stage of SIRs (CSIRs), a miniaturized sext‐band bandpass filter is investigated and fabricated. Purposely, two‐section SIRs with high/low impedance‐ratio are built up for not only enough spurious frequency for sext‐band application, but excellent control on these frequencies. In addition, architecture of CSIR, namely number and arrangement of employed SIRs, is optimized for widening potential frequency range with good response in each passband. Meanwhile, on account of transversal signal interaction concept together with mixed electric magnetic coupling of CSIRI,II, transmission zeros (TZs) and transmission poles (TPs) can be excited alternately. Since coupling is introduced by embedding CSIRs without adding any other structures, configuration of proposed design is compact. Moreover, tapped position of 0° feeding branch can be adjusted for improving filter performance. Therefore, design of miniaturized sext‐band bandpass filter becomes available. Good agreement between simulated and measured results validates the design method.
A COMPARATIVE STUDY ON THE APPLICATION OF BINARY PARTICLE SWARM OPTIMIZATION AND BINARY GRAVITATIONAL SEARCH ALGORITHM IN FEATURE SELECTION FOR AUTOMATIC CLASSIFICATION OF BRAIN TUMOR MRI

Researches on automatic classification for brain tumor had been done extensively, yet there is still room for improvement. Many approaches have been focused on image segmentation and classifier algorithm, yet little number of researches done on feature selection. This paper presents a study on the applications of two popular Swarm Intelligence algorithms: Binary Particle Swarm Optimization and Binary Gravitational Search Algorithm for optimizing feature selection of Gray-Level Co-occurrence Matrix. The classifier that is used in this paper is k-Nearest Neighbor. Benchmarking is done by comparing both swarm intelligence algorithms mentioned. The result indicates Binary Particle Swarm Optimization performs better compared to Binary Gravitational Search Algorithm. Keywords: brain tumor; gray level co-occurrence matrix; nearest neighbor; binary particle swarm optimization; binary gravitational search algorithm
Simultaneous Mass Spectrometry-Based Apolipoprotein Profiling and Apolipoprotein E Phenotyping in Patients with ASCVD and Mild Cognitive Impairment

Apolipoprotein E (apoE) occurs on the majority of plasma lipoproteins and plays a major role in the lipid metabolism in the periphery and in the central nervous system. ApoE is a polymorphic protein with three common isoforms, apoE2, apoE3 and apoE4, derived from respective alleles ε2, ε3 and ε4. The aim of this study was to develop a sample pretreatment protocol combined with rapid mass spectrometry (MS)-based assay for simultaneous apolipoprotein profiling and apoE phenotype identification. This assay was validated in 481 samples from patients with stable atherosclerotic cardiovascular disease (ASCVD) and applied to study association with mild cognitive impairment (MCI) in the LIFE Adult study, including overall 690 study subjects. Simultaneous quantification of 8–12 major apolipoproteins including apoA-I, apoB-100 and apoE could be performed within 6.5 min. Phenotyping determined with the developed MS assay had good agreement with the genotyping by real-time fluorescence PCR (97.5%). ApoE2 isoform was associated with the highest total apoE concentration compared to apoE3 and apoE4 (p < 0.001). In the subgroup of diabetic atherosclerotic cardiovascular disease (ASCVD) patients, apoE2 isoform was related to higher apoC-I levels (apoE2 vs. apoE3, p < 0.05), while in the subgroup of ASCVD patients under statin therapy apoE2 was related to lower apoB-100 levels (apoE2 vs. apoE3/apoE4, p < 0.05). A significant difference in apoE concentration observed between mild cognitive impairment (MCI) subjects and controls was confirmed for each apoE phenotype. In conclusion, this study provides evidence for the successful implementation of an MS-based apoE phenotyping assay, which can be used to assess phenotype effects on plasma lipid and apolipoprotein levels.
A Study of Type II ɛ-PL Degrading Enzyme (pldII) in Streptomyces albulus through the CRISPRi System

ε-Poly-L-lysine (ε-PL) is a widely used antibacterial peptide polymerized of 25–35 L-lysine residues. The antibacterial effect of ε-PL is closely related to the polymerization degree. However, the mechanism of ε-PL degradation in S. albulus remains unclear. This study utilized the integrative plasmid pSET152-based CRISPRi system to transcriptionally repress the ε-PL degrading enzyme (pldII). The expression of pldII is regulated by changing the recognition site of dCas9. Through the ε-PL bacteriostatic experiments of repression strains, it was found that the repression of pldII improves the antibacterial effect of the ε-PL product. The consecutive MALDI-TOF-MS results confirmed that the molecular weight distribution of the ε-PL was changed after repression. The repression strain S1 showed a particular peak with a polymerization degree of 44, and other repression strains also generated ε-PL with a polymerization degree of over 40. Furthermore, the homology modeling and substrate docking of pldII, a typical endo-type metallopeptidase, were performed to resolve the degradation mechanism of ε-PL in S. albulus. The hydrolysis of ε-PL within pldII, initiated from the N-terminus by two amino acid-binding residues, Thr194 and Glu281, led to varying levels of polymerization of ε-PL.
From an Empty Stomach to Anxiolysis: Molecular and Behavioral Assessment of Sex Differences in the Ghrelin Axis of Rats

Ghrelin, a stomach-produced hormone, is well-recognized for its role in promoting feeding, controlling energy homeostasis, and glucoregulation. Ghrelin’s function to ensure survival extends beyond that: its release parallels that of corticosterone, and ghrelin administration and fasting have an anxiolytic and antidepressant effect. This clearly suggests a role in stress and anxiety. However, most studies of ghrelin’s effects on anxiety have been conducted exclusively on male rodents. Here, we hypothesize that female rats are wired for higher ghrelin sensitivity compared to males. To test this, we systematically compared components of the ghrelin axis between male and female Sprague Dawley rats. Next, we evaluated whether anxiety-like behavior and feeding response to endogenous or exogenous ghrelin are sex divergent. In line with our hypothesis, we show that female rats have higher serum levels of ghrelin and lower levels of the endogenous antagonist LEAP-2, compared to males. Furthermore, circulating ghrelin levels were partly dependent on estradiol; ovariectomy drastically reduced circulating ghrelin levels, which were partly restored by estradiol replacement. In contrast, orchiectomy did not affect circulating plasma ghrelin. Additionally, females expressed higher levels of the endogenous ghrelin receptor GHSR1A in brain areas involved in feeding and anxiety: the lateral hypothalamus, hippocampus, and amygdala. Moreover, overnight fasting increased GHSR1A expression in the amygdala of females, but not males. To evaluate the behavioral consequences of these molecular differences, male and female rats were tested in the elevated plus maze (EPM), open field (OF), and acoustic startle response (ASR) after three complementary ghrelin manipulations: increased endogenous ghrelin levels through overnight fasting, systemic administration of ghrelin, or blockade of fasting-induced ghrelin signaling with a GHSR1A antagonist. Here, females exhibited a stronger anxiolytic response to fasting and ghrelin in the ASR, in line with our findings of sex differences in the ghrelin axis. Most importantly, after GHSR1A antagonist treatment, females but not males displayed an anxiogenic response in the ASR, and a more pronounced anxiogenesis in the EPM and OF compared to males. Collectively, female rats are wired for higher sensitivity to fasting-induced anxiolytic ghrelin signaling. Further, the sex differences in the ghrelin axis are modulated, at least partly, by gonadal steroids, specifically estradiol. Overall, ghrelin plays a more prominent role in the regulation of anxiety-like behavior of female rats.
Mismatch locating strategy of photovoltaic array

Single-diode model of Photovoltaic cell is adopted in this paper and is modified by adding a mismatch reflect parameter. The deduced mathematical model of serial PV is provided in this paper. The unknown parameters in the model is determined by the environment conditions including the irradiation and the temperature. With the measured data of the current and voltage values, equation set about the unknown quantities can be listed out. Then iteration method is introduced to solve them. The mismatch reflect parameter is vital to locate the mismatched series in the PV array.
Factors Affecting Employee Turnover Intention and the Moderating Role of Gender: Evidence from the Laborer Category Employees Working in Katunayake Free Trade Zone of Sri Lanka

Although the factors affecting employee turnover intention have been adequately studied in the extant literature in various contexts, minimum attention has been given to studying the actual effect of such factors on the role of gender, especially in the Free Trade Zones in Sri Lanka. Hence, the current study attempts to examine the effect of identified factors from literature, on employee turnover intention with the moderating role of gender on each antecedent. Predominantly adopting the deductive approach, quantitative strategy and crosssectional time horizon, the study was conducted among a sample of 194 employees of the labourer category working in Katunayake Free Trade Zone via a survey questionnaire developed based on standard measurement scales. A simple random sampling technique was used to select the sample while the sample size was determined based on the Morgan table. Data analysis was done employing multiple regression analysis and the moderator analysis with Hayes process v3.5 macro in SPSS 26.0. Findings revealed that job satisfaction and organizational commitment have a negative relationship whereas job performance and job burnout adhere to a strong positive relationship with the employee turnover intention regardless of gender. Further, it is found that gender has no moderating effect on the hypothesized association. Accordingly, it is recommended for human resource professionals to focus more on each controllable factor affecting employee turnover intention which is more likely to convert into actual employee turnover adding costs to organizations in training and development, poor job performance, poor productivity, and emergency recruitments.
Role Fasting In Metabolism And Tumor Progressive

Background: Fasting is the voluntary abstinence from food and drink for a fixed period of time while remaining faithful to certain rules. Fasting has been practiced by humans since ancient time. Fasting involved in the regulation of many metabolic processes correlated with transitioning into a process capable of Energy production and carbon-based metabolism mainly from Tissue adipose and muscular parts. The differences in the levels in the blood hormones and metabolites help to lower and eventually defend normal cells from chemical insults in the cell division and metabolic activityFasting Can induce an anti-warburg response by reducing glucose absorption Carriers (GLUTs) and aerobic glycolysis and force cancer cells to Improve in oxidative phosphorylation (OxPhos); It improves efficiency in cancer cells and, subsequently, toxic products of reactive oxygen (ROS). DNA, p53, DNA damage , and death of the cells , particularly Chemotherapy response,Fasting serves as improving anti-tumour immunity By Fasting or FMD. Conclusion Fasting regulates many physiological functions associated with transitioning into a process capable of producing energy and carbon-based metabolic activity mainly from adipose and muscular tissue. , The fasting action is largely dictated by the levels of glucose, glucagon, insulin, GH, IGF1, and adrenaline in the blood. ,Some many discrepancy in the rates at which hormones and metabolites circulate are normally found during fasting, allowing antitumor response . ,fasting reaction Protects significant nerves and glia but still doesn't prevent glioma or neuroblastoma, Cyclophosphamide, and pro-oxidant Compounds, and preserves the embryonic mouse Doxorubicide fibroblasts.