Miracle-dz/UniFAR-FTUs huggingface dataset:
KUALITI MIKROBIOLOGI AIR DI KILANG ROTI (Microbiological Quality of Water at a Bakery Factory)

The objective of this experiment is to study the microbiological quality of processing water at a bakery factory in Bandar Baru Bangi by using currently installed filtration system. There were 9 sources of water being studied and the water sampling was done 4 times. The microbiological analyses were colony plate count on R2A agar at 22 0 C incubation, total coliforms, faecal coliforms and E.coli type 1 and total Streptococci using MPN methods. On the whole, there were significant differences between total microorganisms in the same water sources but in different sampling and in different water sources but in the same sampling. There were only faecal coliforms presence in the 4 th sampling in B and C water sources and E. coli was absence in all water sources. Negative results were shown for Streptococci in the 3 rd sampling. As a conclusion, the filtration system was not effective to guarantee the good microbiological quality of water in the bakery factory. Base from this study, the factory has changed into a new water filtration system.
System framework of adopting additive manufacturing in mass production line

ABSTRACT System framework is for adopting additive manufacturing (AM) in a mass production line where AM processes are integrated to customize protective parts for manual tools that are found to cause damages of products. The system ensures AM processes are adopted to meet the requirements of functionalities, reliability, line balancing, and the production rate like other conventional processes. The proposed system is different from other AM applications in sense that product designs and fabrications become integrated parts of a production flow. The effectiveness of the system framework is validated as the solution to fix surface mutilations in a truck assembly line.
Monitoring Watering Practices on European Rice Paddy Fields with Sentinel-1: Characterizing European Rice in Multitemporal SAR Sequences for Mapping and Traceability Purposes

Whereas a vast literature exists on satellite-based mapping of rice paddy fields in Asia, where most of the global production takes place, little has been produced so far that focuses on the European context. Detection and mapping methods that work well in the Asian context will not offer the same performances in Europe, where different seasonal cycles, environmental contexts, and rice varieties make distinctive features dissimilar to the Asian case. In this context, water management is a key clue; watering practices are distinctive for rice with respect to other crops, and within rice there exist diverse cultivation practices including organic and non-organic approaches. In this paper, we focus on satellite-observed water management to identify rice paddy fields cultivated with a traditional agricultural approach. Building on established research results, and guided by the output of experiments on real-world cases, a new method for analysing time series of Sentinel-1 data has been developed, which can identify traditional rice fields with a high degree of reliability. This work is a part of a broader initiative to build space-based tools for collecting additional pieces of evidence to support food chain traceability; the whole system will consider various parameters, whose analysis procedures are still at their early stages of development.
Local sport club presidents’ perceptions of collaboration with sport federations

ABSTRACT Purpose: The purpose of this study is to investigate the collaboration between sport federations and their sport clubs by examining club presidents’ perceptions of the relationship between the process and the effectiveness of this collaboration. Design: An online survey was administered to representatives of sport clubs in Wallonia, Belgium (n = 666). Multiple regression analysis was conducted. The independent variables were the five dimensions of the collaboration process and the dependent variables were the club presidents’ perceptions of the effectiveness of the collaboration. Findings: Results indicate that, according to club presidents’ perceptions, the process of collaboration is closely linked to collaboration effectiveness. Moreover, the research highlights that specific process dimensions such as mutuality and trust are closely related to club presidents’ perceptions of the effectiveness of the collaboration. Practical Implications: This research highlights that sport federations and sport clubs should strengthen their interorganisational interdependence and trust in order to collaborate more effectively. Research Contribution: This study contributes to the literature by providing strong empirical evidence that the process of collaboration is closely related to the effectiveness of collaboration between federations and their clubs. Mutuality and trust are particularly crucial for effective collaboration.
The effect of diamine length on the direct solid state polycondensation of semi-aromatic nylon salts

In the current paper, a comparative study on the direct solid state polycondensation (DSSP) reaction of different terephthalate based semi-aromatic salts (XT salts, X = 4–18) in the TGA micro-reactor is reported. High purity XT salts were prepared in solution and were used as starting materials for DSSP. The reaction temperature (TDSSP) for each salt was suitably selected as 20 °C–30 °C below the melting point Tm of the respective salt. The PAXT products were characterized by TGA/DSC, liquid 1H-NMR, and SEM. In the DSSP of XT salts, some diamine is always lost to the gas phase and as a consequence, the attainable molecular weight of the polymer formed gets limited by the unbalance of acid and amine end-groups. The TGA curves show that as the diamine length increases and its volatility decreases, higher molecular weights are obtained. SEM pictures of the products reveal true solid character during the polymerization reaction up to and including PA10T, whereas PA5T, PA12T, and PA18T reveal stickiness and agglomeration during reaction. A possible mechanism explaining such behaviour is also provided. © 2016 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2016, 54, 2493–2506
Historic declines in growth portend trembling aspen death during a contemporary leaf miner outbreak in Alaska

Climate change-driven droughts and insect outbreaks are becoming more frequent and widespread, increasing forest vulnerability to mortality. By addressing the impacts of climate and insects on tree growth preceding death, we can better understand tree mortality risk under a changing climate. Here, we used tree stature and interannual growth (basal area increment; BAI) to assess processes leading to trembling aspen ( Populus tremuloides ) survival or mortality during an unprecedented leaf miner ( Phyllocnistis populiella ) outbreak in boreal North America. We identi ﬁ ed eight sites (22 plots) in the longest running forest monitoring network in Alaska, spanning ~ 350 km of latitude, that experienced ≥ 0.25 Mg (cid:1) ha (cid:3) 1 (cid:1) yr (cid:3) 1 aspen mortality during the outbreak. We compared the size and canopy position, growth patterns, and sensitivity to climate and leaf mining of aspen that survived (living; n = 84) vs. died (dying; n = 76) and linked the normalized difference vegetation index (NDVI) to plot-level aspen growth and stand biomass recruitment, growth, and mortality. Dying aspen were in the subcanopy, smaller in diameter, and after a drought in 1957 had lower growth than living aspen until death. Before the outbreak, growth of all trees was positively in ﬂ uenced by moisture and negatively by temperature, but only living trees maintained this climate response during the outbreak. Leaf mining reduced growth of both groups, exerting at least a twofold greater impact than climate. The NDVI captured plot-level tree growth and stand biomass growth and mortality, yet it was nearly two times more strongly associated with living than dying tree growth and 12 times more strongly associated with biomass growth than mortality. These differences suggest that NDVI may inadequately detect insect-driven dieback and dispersed mortality of aspen across the boreal biome. Our ﬁ ndings reveal that a historic drought triggered a multi-decadal growth decline that predis-posed aspen to mortality during the leaf miner outbreak and that while aspen growth is in ﬂ uenced by moisture and temperature, it is more strongly affected by P. populiella . We conclude that as the climate warms and insect outbreaks increase in frequency and magnitude at high latitudes, we should expect to see persistent and greater declines in aspen growth and increases in mortality.
Predicate-Argument Structure in a Valence Dictionary (on the Example of the Verb Reward)

Valence dictionaries are very often specialized works for advanced readers which present how particular linguistic units combine with its subordinates. The article is a critical analysis of a dictionary entry for the lexical unit of reward contained in A Valency Dictionary of English, a Corpus-Based Analysis of the Complementation Patterns of English Verbs, Nouns and Adjectives [2004]. A complementary proposal regarding the predicate-argument structure and its annotation system will be provided based on the theoretical model proposed by S. Karolak [1984; 2002] called Semantic Syntax (SS) and more specifically its extended model called explicative syntax [Kiklewicz et al. 2010; 2019]. The research findings demonstrate the need for coordinated international projects that should integrate both the syntactic as well as the semantic levels in order to gradually meet the objective of an integrated language description encompassing both the grammar and the lexicon.
Animation in Environmental Journalism: Effects on News Perception and Information Seeking

ABSTRACT An experiment with 413 US participants was conducted to examine the role of animation in environmental journalism. Results show that there was no consistent modality effect (live-action vs. animation) on news perception and information-seeking across environmental topics. Specifically, animation was favored in the communication of fracking. On climate change, concern for the issue moderates the modality’s effect on news perceptions, information-seeking. The findings contribute to the literature of effective visual environmental communication by incorporating the modality effects perspectives, while also offering practical advice on how to effectively use animation to promote audience trust, news enjoyment, information-seeking with various environmental issues.
Stereoblock-like Brush Copolymers Consisting of Poly(l-lactide) and Poly(d-lactide) Side Chains along Poly(norbornene) Backbone: Synthesis, Stereocomplex Formation, and Structure–Property Relationship

Random and block copolymerizations of poly(l-lactide) (PLLA) and poly(d-lactide) (PDLA) macromonomers having an exo-norbornene group at the α- or ω-chain end (D/L ratio = 1/1, Mn = ca. 5000 g mol–1) were performed via ring-opening metathesis polymerization to produce the brush random and block copolymers consisting of parallel or antiparallel aligned PLLA and PDLA side chains on a poly(norbornene) backbone. The molecular weight and polydispersity index of the brush copolymers were in the range of 40 300–458 000 g mol–1 and 1.03–1.14, respectively. Despite such high molecular weights, these brush copolymers formed a stereocomplex without homochiral crystallization. The melting temperature (Tm) and crystallinity (X) of the resulting stereocomplex varied depending on the backbone length, relative chain direction, and distribution of the PLLA/PDLA side chains. The parallel brush copolymers showed significantly higher Tm and X values than the antiparallel ones.
Assessment and Evaluation of Blended Cement Using Bamboo Leaf Ash BLASH Against Corrosion

Concrete provides a high degree of protection against corrosion of embedded steel reinforcement. Owing to the harsh environmental conditions and the presence of aggressive elements from the marine environment, deteriorating corrosion affects the durability of reinforced concrete structures. This study evaluated the effectiveness of bamboo leaf ash BLASH as a supplementary cementing material or admixture with Portland cement to improve the durability of reinforced concrete structures. Specimens of 0, 10, 15, and 20% BLASH mixtures were prepared using 16, 20, and 25 mm steel reinforcements. A total of 100 cylindrical specimens were cast and used in this study. The specimens were accelerated by corrosion using impressed current techniques and a galvanostatic method in a simulated environment. The results show that specimens with a BLASH content of 10% exhibited superior performance and exhibited longer corrosion initiation and propagation times. It has a higher resistance to acid penetration and lower corrosion rates. The crack parameters of the specimen with BLASH admixtures, such as the crack width and crack frequency, were negligible. The use of BLASH as an admixture strengthens its durability and improves its residual strength and serviceability. Doi: 10.28991/cej-2021-03091707 Full Text: PDF
A phase II study of penpulimab, an anti-PD-1 antibody, in patients with relapsed or refractoryclassic Hodgkin lymphoma (cHL).

7529 Background: Penpulimab is a humanized IgG1 monoclonal antibody (mAb) that blocks PD-1 binding to PD-L1. Penpulimab, with its unique binding epitope, was engineered to eliminate Fc-mediated effector function that compromises anti-tumor immune cell function, and to optimize receptor occupancy by improving duration of drug binding. Fc-mediated effector functions, such as ADCC/ADCP, have been observed in most IgG4 anti-PD-1 mAbs but is absent in penpulimab, thereby potentially reducing the occurrence of immune-related adverse reactions. Penpulimab also demonstrated a slower PD-1 antigen binding off-rate than marketed anti-PD-1 mAbs, thereby resulting in better cellular activity and higher receptor occupancy. Penpulimab’s numerous contacts with N58 glycosylation on the BC loop of PD-1 may also contribute to a slower binding off-rate. These structural differentiations of penpulimab enhance its anti-tumor activity and produce a superior safety profile. Methods: AK105-201 is a multicenter, single-arm, open-label study of penpulimab in relapsed/refractory (R/R) cHL. All pts received penpulimab 200 mg Q2W until progression or unacceptable toxicity. Eligible pts had prior autologous stem cell transplant (ASCT) or at least 2 lines of prior chemotherapy. The primary endpoint was ORR based on the Lugano 2014 criteria as assessed by an independent review committee (IRC). Key secondary endpoints included CR rate, DCR, PFS, duration of response (DoR), safety, and tolerability. Results: As of 8 November 2020, of 94 pts (59.6% male, median age 32.0 yrs [31-71], 26.6% was ECOG 1) enrolled, 56 pts remained on treatment, 4 pts completed 24-months treatment and 25 had discontinued (17 due to disease progression, 3 due to AE). After a median follow-up of 15.8 months, the IRC-assessed ORR in the 85 pts evaluable for efficacy was 89.4% (95% CI: 80.8%, 95.0%). A total of 40 patients (47.1%) achieved CR. Median duration of response was not reached with range from 1.7 to 24.5+ months. Median PFS was not reached with 12-months PFS rate was 72.1% ( 95% CI: 60.5%, 80.8%). Treatment-related adverse events (TRAEs, with unlikely-related events included) occurred in 97.9% of pts ( ≥ G3 in 26.6% [25/94], treatment discontinuation in 5.3% [5/94]). Treatment-related SAEs occurred in 10.6%. Most frequent TRAEs (≥20%) were hypothyroidism (31.9%), upper respiratory tract infection (25.5%), fever (24.5%), and ALT elevations (23.4%). Grade ≥3 TRAEs reported in ≥2 pts were platelet count decreased (3.2%), hyperlipemia (3.2%), rash (3.2%), neutrophil count decreased (2.1%). Grade 3 immune-related AEs (irAEs) were reported in 4.3%: IgA nephropathy, pneumonitis, rash, psoriasis (each n = 1) and no G4 or G5 irAEs reported. Conclusions: Penpulimab was shown to be highly active in achieving in a CR rate of 47.1% in pts with R/R cHL while demonstrating lower rates of SAEs, TRAEs leading to discontinuation, and Grade ≥3 irAEs. Clinical trial information: NCT03722147.
Promoting environmental sustainability: the influence of knowledge of eco-labels and altruism in the purchase of energy-efficient appliances

PurposeThe purpose of this study is to extend the theory of planned behavior (TPB) and understand consumers' purchase intention of energy-efficient appliances (EEA) from the perspective of pro-environmental behavior. This study focuses on knowledge of eco-labels (KEL) and altruism for the consumers' purchase intention of EEA.Design/methodology/approachThis study employed a quantitative method. Data of the participants were collected through the purposive sampling technique. A total of 373 valid responses were received with a response rate of 82.88%. Partial least square (SEM) has been used for the analysis of data.FindingsThe findings of the study reveal that altruism and KEL in the extended model of TPB promote the purchase of EEA in Pakistan. Further, the results indicate that altruism was the key predictor that leads to the consumption of environmentally friendly appliances.Practical implicationsEco-labels are important sources that provide specific products related information to consumers. Further, eco-labeling serves to guide consumers' regarding the processes of products' consumption and disposals. Secondly, the positive influence of altruism implies the fact that people have the willingness to contribute to the betterment of the environment and human well-being. Therefore, marketers and policymakers should initiate campaigns that primarily target altruistic consumers and emphasize the importance of the purchase of EEAs that can reduce environmental pollution.Originality/valueThis study would help to understand consumer purchase intention for EEA and contribute to the literature of environmental management. The results of this study would serve to provide guidelines to policymakers and marketers regarding the consumption of environmentally friendly products (EFP).
USP7 Inhibition Induces Apoptosis in Glioblastoma by Stabilizing ARF4

Background: Glioblastomas (GBMs) are grade IV central nervous system tumors characterized by a poor prognosis and a median overall survival of 15 months. The glioblastoma cell population is more genetically unstable, resistant to chemotherapy, more angiogenic, and more malignant. Because ubiquitin-specific proteases (USPs) remove ubiquitin from oncogenic protein substrates, effective inhibition of ubiquitin-specific protease 7 (USP7), which is highly expressed in GBMs, is a potentially critical therapeutic approach. Methods: Immunohistochemistry and Western blotting were used to detect high expression of USP7 in GBM. in vitro studies were performed by Western blotting, immunofluorescence, and flow cytometry to detect apoptosis following inhibition of USP7. Anti-apoptotic substrates of USP7 were defined by Co-IP and TMT proteomics. Nude mouse intracranial xenograft models were constructed to verify whether inhibition of USP7 inhibited the proliferation rate of tumours.Results: USP7 is significantly upregulated in glioblastoma samples. Interfering with USP7 in GBMs induced significant apoptosis, which also occurred after treatment with P5091, a novel small molecule inhibitor of USP7. Mechanistically, apoptosis of GBMs after interference with USP7 function is achieved by stabilizing a key anti-apoptotic protein, ADP-ribosylation factor 4 (ARF4). Furthermore, USP7 interacts directly with ARF4 and catalyzes the removal of the K48-linked polyubiquitinated chain that binds to ARF4, thereby stabilizing the protein. In in vivo experiments, P5091 significantly inhibited tumor growth and promoted the expression of apoptotic genes. Conclusion: Targeted inhibition of USP7 enhances the ubiquitination of ARF4 and ultimately mediates the apoptosis of GBM cells. In a clinical sense, P5091 as a specific inhibitor of USP7 may be an effective approach for the treatment of GBM.
Low-threshold strain-compensated InGaAs/(In,Al)GaAs multi-quantum well nanowire lasers emitting near 1.3 μm at room temperature

Realizing telecom-band lasing in GaAs-based nanowires (NW) with low bandgap gain media has proven to be notoriously difficult due to the high compressive strain built up in the active regions. Here, we demonstrate an advanced coaxial GaAs-InGaAs multi-quantum well (MQW) nanowire laser that solves previous limitations by the introduction of a strain compensating InAlGaAs buffer layer between the GaAs core and the MQW active region. Using a buffer layer thickness comparable to the core diameter applies a significant tensile strain to the GaAs core which efficiently minimizes the compressive strain in the InGaAs MQW and enables large In-content without plastic relaxation. Experimental verification is shown for NW-lasers with an In-content of up to 40% in the MQW, evidencing a clear strain-relieved redshift of the lasing emission and a strong reduction of the lasing threshold compared to highly strained MQWs in state-of-the-art GaAs NW-lasers. This way we achieve optically pumped room temperature lasing operation with a threshold below 50 μJ cm−2 in the telecom O-band close to 1.3 μm.
Nutritional and functional attributes of mungbean (Vigna radiata [L] Wilczek) flour as affected by sprouting time

Sprouting of grains improves their nutritional value and functionality, but information on the appropriate sprouting time required to obtain an optimum quality of mungbean flour is limited. This study evaluated the attributes of mungbean flour as influenced by sprouting time. Mungbean seeds were cleaned, sorted, surface‐sterilised, rinsed and sprouted (28°C and 26% R.H) for 24 to 120 hr. Proximate, amino acids (AA), vitamins, mineral, anti‐nutritional (phytate, tannin, oxalate, trypsin inhibitor, raffinose and stachyose) composition, functional properties (viscosity, bulk density and swelling index), microbial quality (total plate and mould counts) and energy of the flours obtained from the sprouted seeds were analysed. Data were subjected to analysis of variance and the means separated by Duncan's Multiple Range Test. Significant (P < 0.05) differences were observed in the energy contents, chemical and functional properties of mungbean flour. There was no fungal growth in the samples until after 72 hr. Leucine, followed by lysine, was the dominant essential AA while methionine was the least. In conclusion, increase in sprouting period improved the nutrient composition but reduced the anti‐nutrients of mungbean flour. Samples sprouted for 24 hr had the highest total essential and conditionally essential AA.
Who are the users of national open access journals? The case of the Finnish Journal.fi platform

In this paper we study the diversity of users of open access articles on the Finnish Journal.fi platform. This platform hosts around hundred open access journals from Finland publishing in different fields and mainly Finnish and English languages. The study is based on an online survey, conducted on 48 journals during Spring 2020, in which visitors were asked to indicate their background and allow their location and download behaviour be tracked. Among 668 survey participants, the two largest groups were students (40%) and researchers (36%), followed by private citizens (8%), other experts (7%) and teachers (5%). Other identified user categories include journalists, civil servants, entrepreneurs and politicians. While new publications attract a considerable share of the views, there is still a relatively large interest, especially among students, in older materials. Our findings indicate that Finnish language publications are particularly important for reaching students, citizens, experts and politicians. Thus, open access to publications in national languages is vital for the local relevance and outreach of research.