Miracle-dz/UniFAR-FTUs huggingface dataset:
Barriers to Clinical Practice Guideline Implementation Among Physicians: A Physician Survey

Introduction Clinical practice guidelines can help physicians provide evidence-based, standardized clinical decisions. We aimed to assess physician attitudes toward and barriers to guideline adherence. Methods We conducted a single center, cross-sectional, survey-based study. Physicians from many specialties participated in the study. All outcomes were measured using a validated survey tool. The primary outcome of interest was barriers to guideline adherence. Secondary outcomes included general attitudes toward guidelines and factors that could improve adherence to guidelines. Outcomes were measured by the survey tool. All outcomes were reported on a 5-point Likert scale. Results The email survey was received by 1819 physicians with 400 responders (22% response rate). About 50% (n=200) were in practice for >5 years, while 27% (n=107) were still in training. Trainees were less likely to understand the process of guideline development (RR= 0.76 [0.65–0.88], p=0.0017), to have input in guideline development (RR= 0.52 [0.41–0.65], p<0.0001), and to report up-to-date knowledge in practice guidelines (RR=0.53 [0.30–0.73], p=0.0002). Three factors were identified as major barriers to guideline adherence: complexity of guideline documents (61%, n=240), high number of weak or conditional recommendations (62%, n=245), and time constraints due to clinical responsibilities (65%, n=255). Factors that would improve guideline adherence included access to relevant guidelines at the point of care (87%), improved focus on guidelines during training (82%), and transparency on physician commercial affiliation (62%). Conclusion Improved focus on guidelines during training and access to relevant guidelines at the point of care may be important to improve adherence to guidelines.
Host Defense Peptide-Mimicking Polymers and Polymeric-Brush-Tethered Host Defense Peptides: Recent Developments, Limitations, and Potential Success

Amphiphilic antimicrobial polymers have attracted considerable interest as structural mimics of host defense peptides (HDPs) that provide a broad spectrum of activity and do not induce bacterial-drug resistance. Likewise, surface engineered polymeric-brush-tethered HDP is considered a promising coating strategy that prevents infections and endows implantable materials and medical devices with antifouling and antibacterial properties. While each strategy takes a different approach, both aim to circumvent limitations of HDPs, enhance physicochemical properties, therapeutic performance, and enable solutions to unmet therapeutic needs. In this review, we discuss the recent advances in each approach, spotlight the fundamental principles, describe current developments with examples, discuss benefits and limitations, and highlight potential success. The review intends to summarize our knowledge in this research area and stimulate further work on antimicrobial polymers and functionalized polymeric biomaterials as strategies to fight infectious diseases.
EVALUATION OF CARDINAL TEMPERATURES AND THERMAL TIME REQUIREMENT FOR GERMINATION OF SCROPHULARIA STRIATA AND TANACETUM POLYCEPHALUM (SCHULTZ BIP. SSP. HETEROPHYLLUM)

Scrophularia striata and Tanacetum polycephalum are important medicinal plants in Iran which are rich inessential oils, bitter substances, and sesquiterpene lactones. The present study was conducted to compare fournon-linear regression models (segmented, beta, beta modified and Dent-like) to describe the germination ratetemperaturerelationships of Scrophularia striata and Tanacetum polycephalum over eight and seven constanttemperatures, respectively, to find cardinal temperatures and thermal time requirements to reach differentgermination percentiles. An iterative optimization method was used to calibrate the models and differentstatistical indices including RMSE, coefficient of determination (R2), and AICc were applied to compare theirperformance. The beta model was found to be the best model to predict germination rate of Scrophulariastriata at D10, D50 and D90 (R2 = 0.96, R2 = 0.97, R2 = 0.95; RMSE = 0.005, 0.001 and 0.001, respectively). According to this model outputs, the base, optimum, and the maximum temperatures for germination wereestimated as 1.21 ± 0.39, 25.91 ± 0.33 and 46.35 ± 4.12 °C, respectively. Also the segmented model wasfound to be the best model to predict germination rate of Tanacetum polycephalum at D10, D50 and D90 (R2= 0.98, R2 = 0.98, R2 = 0.98; RMSE = 0.067, 0.59 and 0.56, respectively). According to the model outputs, thebase, optimum, and the maximum temperatures for germination were estimated as 0.44±1.15, 26.95±0.75 and38.33±0.98 oC, respectively. It seems these two medicinal plants need moderate optimum temperature for seedgermination.
Design and Fabrication of a Printed Tri-Band Antenna for 5G Applications Operating across Ka-, and V-Band Spectrums

In this paper, an umbrella-shaped patch antenna for future millimeter-wave applications for the 5G frequency band is presented. The proposed antenna resonates at multiple frequency bands, i.e., 28 GHz, 38 GHz, and 55 GHz (V-band) that have been globally allocated for 5G communications systems. The proposed antenna is designed using Rogers RT/duroid 5870, with a relative permittivity, loss tangent and thickness of 2.33 mm, 0.0012 mm and 0.79 mm, respectively. The antenna has an overall size of 8 mm × 8 mm which correspond to 0.7 λ × 0.7 λ, where λ is free space wavelength at the lowest resonance. Moreover, the wide bandwidth, high gain and tri band operational mode is achieved by introducing two stubs to the initial design. The antenna prototype was fabricated and validated experimentally. The comparison of the simulated and measured results demonstrates a good correlation. Additionally, the comparative analysis with state of the art work demonstrates that the proposed antenna offers compact size, simple geometrical configuration, wide bandwidth, high gain, and radiation efficiency which makes the proposed antenna a potential candidate for compact smart 5G devices.
Signal Processing for Micro Inertial Sensors

Abstract : In the development of the guidance and control packages for unmanned vehicles, it is highly desirable to have inertial measurement sensors which are small, inexpensive, low power, reliable and accurate. New technological advances in the design and construction of micro inertial sensors, such as accelerometers and gyroscopes, have much promise in providing small, inexpensive, and low power devices; however, much improvement in the reliability and, especially, the accuracy of these micro devices is still necessary. Further major improvements in these two properties will probably not be accomplished in the near future, thus it will be necessary to use special signal processing methods to provide the accuracy. One way which has been proposed to improve the accuracy, and concurrently the reliability, of micro sensors is to use many, perhaps one hundred or more, micro sensors on a single chip (or a few chips) and using statistical methods to combine the individual outputs of these sensors to provide an accurate measurement. One method of performing such a combination is through an extended Kalman filter (EKF). A standard application of an EKF to an array of gyroscopes would involve at least six state equations per gyroscope and the number of covariance equations would be in the order of the square of the product of six times the number of gyroscopes. Obviously, the curse of dimensionality very quickly limits the number of sensors (gyroscopes) which can be used. Even if the EKF for each individual gyroscope is uncoupled from the rest, the number of covariance equations is of the order of the number of gyroscopes times six squared. This can still lead to a formidable computational burden. In this paper, a new technique of applying an EKF to this problem of combining many sensors is proposed. By using the common nominal model for each of the micro sensors and developing a single EKF, improved accuracy is achieved by a single EKF with the dimension of one sensor.
Including functional and non-technical requirements in a software requirement patterns catalogue

Taking into account the drawbacks presented above for each asset in the PABRE framework, the objectives of this thesis are: 1. Do a systematic review of the existent published works on reuse in Requirements Engineering stage, particularly on the use of patterns to achieve the reuse of requirements during Requirements Engineering. 2. Construction of a complete set of non-technical SRP that can be obtained from the Software Requirement Specifications (SRSs) corresponding to 6 real projects. 3. Study of the Content Management System domain and construction of some examples of functional SRP for this domain from the same 6 SRSs. 4. Check the validity of the current SRP metamodel for its suitability for non-technical and functional SRPs. 5. Validate the structure of SRPs (as it is the base of this thesis) and construct a survey which will be used to know what requirements engineers think about the usability of SRP catalogues in real projects in their different enterprises or organizations and if it will be applicable or not.
The Impact of Musculoskeletal Injuries Sustained in Road Traffic Crashes on Work-Related Outcomes: A Systematic Review

Musculoskeletal injuries occur frequently after road traffic crashes (RTCs), and the effect on work participation is not fully understood. The primary aim of this review was to determine the impact of sustaining a musculoskeletal injury during an RTC on the rate of return to work (RTW), sick leave, and other work outcomes. The secondary aim was to determine factors associated with these work-related outcomes. An electronic search of relevant databases to identify observational studies related to work and employment, RTC, and musculoskeletal injuries was conducted. Where possible, outcome data were pooled by follow-up period to answer the primary aim. Fifty-three studies were included in this review, of which 28 were included in meta-analyses. The pooled rate of RTW was 70% at 1 month, 67% at 3 months, 76% at 6 months, 83% at 12 months, and 70% at 24 months. Twenty-seven percent of participants took some sick leave by one month follow-up, 13% by 3 months, 23% by 6 months, 36% by 12 months, and 22% by 24 months. Most of the factors identified as associated with work outcomes were health-related, with some evidence also for sociodemographic factors. While 70% of people with RTC-related musculoskeletal injury RTW shortly after accident, many still have not RTW two years later.
Warehouse Operations Revisted : Novel Challenges and Methods

In today’s e-commerce business, continuous technological development, high competition, demand fluctuations, and especially service standard requirements pose enormous challenges for the logistics operations of a company. To satisfy these requirements traditional logistics processes have to be reconsidered and potentially restructured to facilitate logistics efficiency on the one hand, as well as quick and reliable delivery guarantees on the other hand. This dissertation deals with new problems which arise in this context for the operational procedures of commercial warehouses and in particular for the order picking operations. Order picking operations contribute to more than 55 percent to the overall operation costs of warehouses. We propose solution methods, which are capable of integrating product returns in order batching and order picker routing methods, since returns processing has become a substantial part of the daily operations in warehouses. Many product returns are nowadays common for most e-commerce retailers, since the opportunity to shop online is usually accompanied with very liberal return policies. In warehouses those returns lead to additional cost and labor effort, as the products have to be inspected, re-packaged, and reintegrated in the stock before they can be resold. Cost-efficiency as well as accurate inventory management are therefore significantly affected by the processing of returns. Besides, we study a staff planning problem for warehouses in situations of high workforce demand fluctuations. Labor is usually highly cost-intensive and has to be used most efficiently by optimal scheduling. We discuss five optimization approaches to incorporate risk management in a staff schedule optimization and present a decision tool for warehouse managers which can assist in deriving low-cost solutions by simultaneously controlling risks of shortages.
From Amines to Alkynes – Lighting the Way

We present a metal-free photoredox strategy for the formation of Csp3-Csp bonds from redox-activated primary amine derivatives. The developed reaction of 2,4,6-triphenylpyridiniu salts with alkynyl tosylates, leading to functionalized alkynes , is easily scalable, offers broad substrate scope, high chemoselectivity, and mild conditions. Its potentials also highlighted by diversification of complex molecular scaffolds. Moreover, mechanistic studies contribute to the elucidation of unexpected differences in reactivity of primary, secondary and alkyl pyridinium salts.
Digital Companion Choice to Support Teachers’ Stress Self-management: Systematic Approach Through Taxonomy Creation

Background There are thousands of digital companions designed for emotional well-being and stress, including websites, wearables, and smartphone apps. Although public evaluation frameworks and ratings exist, they do not facilitate digital companion choice based on contextual or individual information, such as occupation or personal management strategies. Objective The aim of this study is to establish a process for creating a taxonomy to support systematic choice of digital companions for teachers’ stress self-management. Methods We used a 4-step study design. In step 1, we identified the dimension of stress self-management and strategic classifications. In step 2, we identified the dimension of the digital techniques and conceptual descriptions. In step 3, we created 6 criteria for the inclusion of digital companions. In step 4, we used the taxonomy framework created by steps 1 and 2 and populated it with digital companions for stress self-management, as identified in step 3. Results First, in the dimension of stress self-management, we identified four classes of strategies: educational, physiological, cognitive, and social. Second, in the digital techniques dimension, we derived four conceptual descriptions for the digital companions’ mechanisms of action: fostering reflection, suggesting treatment, peer-to-peer support, and entertainment. Third, we created six criteria for digital companion inclusion in the taxonomy: suitability, availability, evaluation, security, validity, and cost. Using the taxonomy framework and criteria, we populated it with digital companions for stress management ahead of presentation to teachers in a stress study workshop. Conclusions The elements of our approach can be generalized as principles for the creation of taxonomies for other occupations or conditions. Taxonomies such as this could be a valuable resource for individuals to understand which digital companion could be of help in their personal context.
Development of a 10 metre shuttle walking test to access patients with chronic airways limitation.

The purpose of this study was to develop an incremental field exercise test of disability to use in the assessment of functional capacity in patients with chronic airways limitation (CAL). The test was modified from the 20m shuttle running test, employed to predict the maximal oxygen uptake of sporting individuals. The protocol devised for the patients was adapted from the running speeds proposed by Leger and Lambert (1982). The shuttle walking test requires patients to walk up and down a 10m course at speeds dictated by a series of audio signals played from a tape cassette, increasing each minute to a symptom limited maximum performance. Examination of the reproducibility of the test revealed strong test/retest reliability, after just one practice walk. The mean between trial difference (test 2 vs test 3) was -2m,(n=10), (95% CI -21.9 to 17.9m). The shuttle walking test was validated against the traditional measurement of peak oxygen uptake (Vo2pmk) measured conventionally during an incremental maximal treadmill test with Douglas bags (n=19). The results from this exercise test were compared against the patients' performance (distance achieved) on the shuttle walking test (after one practice walk) and revealed a strong relationship between the two variables (r=0.88). The validity and the resistance to breathing, of a portable oxygen consumption meter was examined. Validation, again in comparison to Douglas bag measurements, involved four cohorts (two healthy and two patient groups). After some modifications to the equipment, measurements of lib2 by the two different methods were not significantly different. The patients' response to the shuttle walking test was examined (n=10). The heart rate, ventilation and 7Orck2 increased gradually in response to the increasing intensity of the shuttle walking test. Again Vo 2wa measurements related strongly to the patients performance (r=0.81). A further study employing a treadmill test and shuttle walking test confirmed that the latter provided a comparable metabolic and physiological challenge to the patients as the conventional treadmill test. Comparison with the 6 minute walking test (6MWT), one of the most commonly employed field exercise tests in this patient population) revealed that the heart rate response was significantly higher in the shuttle walking test than the 6 MWT and graded, a response not observed in the 6MWT. The shuttle test reflected the true extent of the patients disability more accurately than the 6MWT. The shuttle walking test provides a simple, reproducible exercise test of disability in patients with CAL that relates well to Vb2puk . The external pacing of the test allows more valid intra- and inter- subject comparison than has previously been possible with field tests alone.
Synthesis of Pyrimidinyl Benzazolyl Urea Derivatives as Antimicrobial and Antioxidant Agents

Abstract A library of pyrimidinyl benzazolyl urea derivatives were synthesized from pyrimidine-2- amine and methyl benzazolylcarbamate in the presence of potassium tert-butoxide in DMF. The compounds with benzothiazolyl and benzimidazolyl moieties having chloro and nitro substituents on the aromatic ring exhibited prominent antibacterial activity against Bacillus subtilus. Nitro substituted pyrimidinyl benzothiazolyl urea and pyrimidinyl benzimidazolyl urea displayed prominent antifungal activity against Asperigellus niger. The compounds with benzoxazole moiety showed greater radical scavenging activity than those with benzothiazole and benzimidazole units.
Signaling and Predatory Mimicry in India’s Naxalite Lands

Extralegal and rebel organizations often extort civilians to raise funds for their operations. A key issue in this process is overcoming informational asymmetries regarding extortionists’ membership in the extralegal organization. In this paper, I examine how victims determine if an extortionist belongs to an extralegal organization, in this case a left-wing guerrilla/terrorist group in India called the Naxalites, or is merely a “deceptive mimic” (a fake)? I interview police, victims of extortion, Naxalites, and arrested Naxalite mimics to understand how the Naxalites use costly signals to “help” victims distinguish real Naxalites from Naxalite mimics. Naxalites’ tactics include quoting Marxist-Leninist literature to appear learned, singing revolutionary songs, carrying guns, and bringing along female rebels. I find that a key feature differentiating a small group of extortionists from an organized rebel group is the latter’s ability to use a large and efficient network to gather information about victims finances. For high-valued victims, Naxalites use these resources at a relatively lower cost than unorganized mimics to gather information about victims’ assets or recent earnings. By using this information to set their extortion price precisely and by revealing they know details about the victim that are hard to learn, they authenticate their claims to group membership. However, I also discover two types of situations in which Naxalite mimics succeed in passing as Naxalites. First, even though the Naxalite mimics sometimes use low-cost signals and demand small amounts of money, risk-averse victims fall prey when they are not able to see that it is not worth the time of real Naxalites to demand small sums given their higher expected costs of punishment if caught. Costs of punishment are expected to be higher for real Naxalites because they will also face terrorism charges. Second, I discover that some mimics are ex-Naxalites, who are more or less as capable of using costly signals as the Naxalites and therefore succeed.
Experiències òptimes de navegació i compra en línia: una aproximació al comportament del consumidor a la Xarxa mitjançant el concepte de flux

Interest in understanding the phenomena of online shopping and surfing has grown in recent years in light of the business opportunities offered by the Internet. And although consumer behaviour in the medium retains certain features in common with behaviour in conventional commercial environments, it also incorporates new elements which, like the experiences of flow, deserve special attention from companies and academics. This article identifies some of the specificities of online shopping experiences, it analyses consumer motivation and behaviour in virtual shopping environments and the contribution of the flow concept in understanding online consumption experiences. On the basis of the work conducted, note is made of the relationships between the phenomena of flow and the different surfing and shopping behaviour: those geared towards achieving a specific shopping aim and those of a predominantly exploratory or hedonistic nature.
Challenges of Platooning on Public Motorways

Road-trains or platoons present a significant opportunity to both improve traffic efficiency and to improve the efficiency and safety of vehicles within the platoon. However, for platoons to be viable there should be minimal impact on supporting infrastructure which implies that platoons will operate on unmodified public motorways. The European Commission FP7 co-funded SARTRE project aims to examine issues for allowing platoons to operate on public motorways under these conditions. This paper discusses the SARTRE concept of platoons and the associated challenges such as interaction with other road users. Descriptions of core concept and definitions are made. Initial simulations are described and presented. A brief overview of the communication system is made.
IS INJURY OCCURRENCE ASSOCIATED WITH JOINT COUPLING VARIABILITY DURING UNANTICIPATED MOVEMENT TASKS PERFORMED BY NETBALLERS

This study determined whether lower extremity joint coupling variability (JCV) measures during unanticipated change of direction movements were associated with prospective lower limb injury occurrence in netballers. Twelve elite injury-free female netballers performed five trials of unanticipated sprinting tasks (straight sprints and sprints with a 180° turn on their dominant and non-dominant legs) in the motion analysis laboratory from a 10 m approach. Lower extremity JCV measures were calculated for all movement tasks from 3D data. All netballers were monitored prospectively for a period of six months for the occurrence of lower limb injury. Five (42%) netballers sustained an injury with all injuries on their dominant leg. Low joint coupling variability was associated with injury occurrence in elite female netballers (r = 0.66).