Miracle-dz/UniFAR-FTUs huggingface dataset:
The Rare Case of Esophageal Cancer Presenting With Hematemesis in a 29-Year-Old Adult

Esophageal cancer is a disease with high mortality. This is mainly due to late presentations with nonspecific symptoms. Despite advances in surgery and chemoradiotherapy, it is the eighth most common cancer but the sixth deadliest. It is reportedly common in older patients but rare in young ones. In this case report, we present a 29-year-old male patient with no prior medical condition who presented with hematemesis to the emergency unit and was found to have esophageal cancer with the biopsy. Not only is esophageal cancer rare in young adults, but hematemesis is a rare symptom in esophageal cancer patients.
A Triazaspirane Derivative Inhibits Migration and Invasion in PC3 Prostate Cancer Cells

Cancer is a serious health problem due to the complexity of establishing an effective treatment. The purpose of this work was to evaluate the activity of a triazaspirane as a migration and invasion inhibitor in PC3 prostatic tumor cells through a possible negative regulation of the FAK/Src signal transduction pathway and decreased secretion of metalloproteinases 2 and 9. Molecular docking analysis was performed using Moe 2008.10 software. Migration (wound-healing assay) and invasion (Boyden chamber assay) assays were performed. In addition, the Western blot technique was used to quantify protein expression, and the zymography technique was used to observe the secretion of metalloproteinases. Molecular docking showed interactions in regions of interest of the FAK and Src proteins. Moreover, the biological activity assays demonstrated an inhibitory effect on cell migration and invasion, an important suppression of metalloproteinase secretion, and a decrease in the expression of p-FAK and p-Src proteins in treated PC3 cells. Triazaspirane-type molecules have important inhibitory effects on the mechanisms associated with metastasis in PC3 tumor cells.
Design of Vegetation Index for Identifying the Mosaic Virus in Sugarcane Plantation: A Brazilian Case Study

Phytosanitary control of crops requires the rapid mapping of diseases to enable management attention. This study aimed to evaluate the potential of vegetation indices for the detection of sugarcane mosaic disease. Spectral indices were applied to hyperspectral images collected by an unmanned aerial vehicle (UAV) to find the areas affected by the mosaic virus in sugarcane. Identifying indices capable of detecting diseased plants in agricultural crops supports data processing and the development of efficient tools. A new index was designed based on spectral regions, which presents higher differences between healthy and mosaic virus-infected leaves to enhance hyperspectral image pixels representing diseased plants. Based on the data generated, we propose the anthocyanin red edge index (AREI) for mosaic virus detection in sugarcane plantations. An index that can adequately identify sugarcane infected by the mosaic virus may incorporate wavelengths associated with variations in leaf pigment concentrations as well as changes in leaf structure. The indices that assessed to detect plants infected with the sugarcane mosaic virus were the normalised difference vegetation index (NDVI), normalised difference vegetation index red edge (nDVI705), new vegetation index (NVI), ARI2 and AREI. The results showed that AREI presented the best performance for the detection of mosaic in sugarcane from UAV images, giving an overall accuracy of 0.94, a kappa coefficient of 0.87, and omission and inclusion errors of 2.86% and 10.52%, respectively. The results show the importance of wavelengths associated with the concentration of chlorophyll and anthocyanin and the position of the red edge for the detection of diseases in sugarcane.
Comparison of Return-to-Sports Rates Between Male and Female Australian Athletes After ACL Reconstruction

Background: Return to sports (RTS) is a goal for most patients who undergo anterior cruciate ligament reconstruction (ACLR). Although it has been reported that women RTS at a significantly lower rate compared with men, demographic and contextual factors that may be associated with this have not been investigated. Purpose: To compare RTS rates between men and women and investigate factors that may be associated with different rates of RTS in an Australian context. Study Design: Cohort study; Level of evidence, 3. Methods: A total of 1338 patients who underwent primary ACLR between January 2014 and December 2017 were invited to complete a detailed sports participation questionnaire 2 to 7 years after surgery. RTS rates were calculated and compared between men and women overall and after stratifying by age at surgery (<20, 20-29, 30-39, or ≥40 years) and geographical location (metropolitan or rural). Contingency analysis was performed to compare factors associated with rates of RTS. Results: The survey completion rate was 81% (1080/1338). Overall, women had a significantly lower RTS rate compared with men (65.4% vs 74.9%; P = .001). However, when patients were grouped by age, the lower rate of RTS for women was significant only in the 20- to 29-year age group (P = .01). For athletes who returned to sports, there was no sex-based difference when comparing the levels of RTS. When grouping patients based on geographical location, there was a significantly lower rate of RTS in metropolitan-based women compared with metropolitan-based men (P < .001) and rural-based women (P = .042). Conclusion: Although women returned to sports at a lower rate than men overall, this difference was predominantly seen in the 20- to 29-year age bracket and in those who lived in metropolitan areas. There was no difference between men and women regarding the RTS level.
CARACTERIZAÇÃO DO PERFIL EPIDEMIOLÓGICO DE PACIENTES COM CÂNCER DO COLO DO ÚTERO NO CEARÁ DURANTE O PERÍODO DE 2013 A 2022

O câncer do colo do útero (CCU) é um dos carcinomas de maior incidência em todo o mundo e uma das principais causas de óbito na população feminina. De acordo com o Instituto Nacional de Câncer – INCA, para o ano de 2023, foi estimada uma projeção de ocorrência de 604 mil novos casos de CCU no mundo. Sem considerar os tumores de pele não melanoma, o CCU é o sexto tipo de câncer mais incidente entre a população geral brasileira, o terceiro câncer mais frequente entre o sexo feminino. Entre os anos de 2013 e 2022, o Ceará ocupou a nona colocação entre os estados com maior incidência de CCU no Brasil. Tendo o CCU como um importante problema de saúde pública, este estudo tem como objetivo realizar um levantamento epidemiológico do carcinoma no Ceará. Trata-se de um estudo observacional, analítico e transversal. Entre o período de 2013 a 2022, foram registrados 6,076 novos casos de CCU entre a população residente do Estado do Ceará, correspondendo à cerca de 4,5% dos casos notificados em território nacional. A faixa etária de 35 a 59 anos de idade foi a mais afetada. As maiores incidências de CCU foram atribuídas aos estádios II e III. Desta forma, podese observar semelhanças compartilhadas entre o Estado do Ceará e regiões subdesenvolvidas de modo geral, onde o perfil de pacientes diagnosticados com CCU são predominantemente classificados como portadores de doença localmente avançada.
An ultra‐wideband MIMO system with multi‐loop mode for full‐screen smartphone applications

In this letter, an ultra‐wideband (UWB) eight‐element multiple‐input multiple‐output (MIMO) antenna system with multi‐loop modes for fifth‐generation (5G) smartphones is presented. The antenna unit has a simple structure and is composed of an inverted U‐shaped feeding strip and an L‐shaped grounding radiation strip with a hollow out in the middle. Owing to the generation of two coupling loop modes, the working bandwidth of the proposed antenna unit covers 3.2−6.4 GHz. Besides, the simulated and measured results show that the isolation between any two antennas is better than 12.0 dB, and the total efficiency of each element is higher than 50%. Meanwhile, the measured radiation pattern, envelope correlation coefficients, channel capacity loss, mean effective gain, and diversity gain are also given in this letter. The above results demonstrate that the MIMO system has the advantages of simple structure, convenient manufacture, and superior performance.
A sub-solar metallicity is required for superluminous supernova progenitors

Host galaxy properties provide strong constraints on the stellar progenitors of superluminous supernovae. By comparing a sample of 18 low-redshift superluminous supernova hosts to a volume-limited galaxy population in the local Universe, we show that sub-solar metallici- ties seems to be a requirement. All superluminous supernovae in hosts with high measured gas-phase metallicities are found to explode at large galactocentric radii, indicating that the metallicity at the explosion site is likely lower than the integrated host value. We also confirm that high specific star-formation rates are a feature of superluminous supernova host galaxies, but interpret this as simply a consequence of the anti-correlation between gas-phase metallic- ity and specific star-formation rate and the requirement of on-going star formation to produce young, massive stars greater than ~ 10-20 M_sun . Based on our sample, we propose an upper limit of ~ 0.5 Z_sun for forming superluminous supernova progenitors (assuming an N2 metal- licity diagnostic and a solar oxygen abundance of 8.69). Finally, we show that if magnetar powering is the source of the extreme luminosity then the required initial spins appear to be correlated with metallicity of the host galaxy. This correlation needs further work, but if it holds it is a powerful link between the supernova parameters and nature of the progenitor population.
An Overview of Risk Factors for Diabetic Foot Amputation: An Observational, Single-centre, Retrospective Cohort Study

Introduction: Not only are early detection and treatment of diabetic foot ulcers important, but also acknowledging potential risk factors for amputation gives clinicians a considerable advantage in preventing amputations. Amputations impact both healthcare services and the physical and mental health of patients. This study aimed to investigate the risk factors for amputation in patients with diabetic foot ulcers. Methods: The sample for this study was patients with diabetic foot ulcers who were treated by the diabetic foot council at our hospital between 2005 and 2020. A total of 32 risk factors for amputation were identified and investigated among 518 patients. Results: Our univariate analysis showed that 24 of 32 defined risk factors were statistically significant. In the multivariate analysis using the Cox regression model, seven risk factors remained statistically significant. The risk factors most significantly associated with amputation were Wagner grading, abnormal peripheral arteries, hypertension, high thrombocyte levels, low haematocrit levels, hypercholesterolaemia and male sex, respectively. The most common cause of death in patients with diabetes who have undergone amputation is cardiovascular disease, followed by sepsis. Conclusion: To enable optimum treatment of patients with diabetic foot ulcers it is important for physicians to be aware of the amputation risk factors, and thus avoid amputations. Correcting risk factors, using suitable footwear and routinely inspecting feet are crucial factors for preventing amputations in patients with diabetic foot ulcers.
Cutaneous Sarcoidosis: A Differential Diagnosis to Consider in Undiagnosed Skin Lesions

The presentation of sarcoidosis varies depending on the organs involved. Cutaneous sarcoidosis usually presents with other organ involvement, but isolated presentation is possible. However, diagnosing isolated cutaneous sarcoidosis can be challenging in resource-poor countries, particularly where sarcoidosis is relatively uncommon, since cutaneous sarcoidosis usually does not cause troublesome symptoms. We present a case of cutaneous sarcoidosis in an elderly female who had been suffering from skin lesions for nine years. The diagnosis was made after the appearance of lung involvement, which raised the suspicion of sarcoidosis and prompted a skin biopsy. The patient was then treated with systemic steroids and methotrexate, and her lesions improved shortly thereafter. This case highlights the importance of considering sarcoidosis as a possible cause of undiagnosed, refractory cutaneous lesions.
Optimal Pseudo-Gaussian and Rank-Based Tests of the Cointegration Rank in Semiparametric Error-Correction Models

This paper provides locally optimal pseudo-Gaussian and rank-based tests for the cointegration rank in linear cointegrated error-correction models with i.i. d. elliptical innovations. The proposed tests are asymptotically distribution-free, hence their validity does not depend on the actual distribution of the innovations. The proposed rank-based tests depend on the choice of scores, associated with a reference density that can freely be chosen. Under appropriate choices they are achieving the semiparametric efficiency bounds; when based on Gaussian scores, they moreover uniformly dominate their pseudo-Gaussian counterparts. Simulations show that the asymptotic analysis provides an accurate approximation to finite-sample behavior. The theoretical results are based on a complete picture of the asymptotic statistical structure of the model under consideration.
Magnetic fields in AGB stars and (proto-) Planetary Nebulae

Abstract During its quick transition to the Planetary Nebula stage, the Asymptotic Giant Branch star will completely change its geometry. This AGB stellar evolution stage is characterized by a high mass loss driven by the radiation pressure. Strong magnetic field may rule the mass loss geometry and the global shaping of these objects. Following our previous work on the polarization of the SiO maser emission in a representative sample of O-rich evolved stars, we present here a study towards C-rich objects and PPN/PN objects to obtain unbiased conclusions. Using Xpol at the IRAM-30 m telescope, we have conducted CN N=1-0 observations to investigate the Zeeman effect in this molecule and draw conclusion on the evolution of the magnetic field and its influence during the transition of an AGB star to the PN stage. Following the analysis described by Crutcher et al. (1996) we derive an estimate of the magnetic field.
CMFTC: Cross Modality Fusion Efficient Multitask Encrypt Traffic Classification in IIoT Environment

Traffic classification, which deduces task-relevant traffic types, is required for network management, security, and quality of service (QoS). In recent studies, deep learning has been used to distinguish encrypted traffic without using handcraft features. However, higher-performance deep learning models often come with a significant computational overhead and parameter count. In this article, we present a novel cross-modal fusion model, CMFTC, which achieves comparable performance to the state-of-the-art (SOTA) model DISTILLER, but with only 18% of its parameters and half the floating-point operations (FLOPs). The CMFTC model is designed to carefully capture the relationship between different modalities and employs a lightweight design for efficient computation. Our model achieves better performance by fusing packet, context, and flow-level modalities. Additionally, we propose a pair of homogeneous student and teacher models with similar architectures, and we adjust the distillation algorithm to improve the student model's inference speed without compromising performance. Our experimental results demonstrate that the proposed model outperforms the current SOTA on several benchmark datasets, including Ton_IoT, IoT-23, ISCX-Tor-2016, ISCX-VPN-2016, and USTC-TFC, with significantly fewer parameters and FLOPs. Furthermore, our model has a better inference speed on real IoT devices, as demonstrated by our experiments.
V-Recover: Virtual Machine Recovery When Live Migration Fails

Live migration is a critical technology used in cloud infrastructures to transfer running virtual machines (VMs). When live migration fails, as it often does, it is critical that any VMs in transit are not lost. There are two primary live migration techniques – pre-copy and post-copy. Pre-copy transfers a VM's memory to the destination before its virtual CPUs are transferred, whereas post-copy does the reverse. Both pre-copy and post-copy will lose the VM if the source machine fails during migration. Additionally, post-copy can lose the VM if the destination machine or network fail since the VM's memory and execution state are split across the source and destination machines. We present V-Recover, an approach to recover a VM when the source, destination, or network fails during live migration. V-Recover consists of two techniques: (1) a forward incremental checkpointing (FIC) mechanism to handle source machine failure during both pre-copy and post-copy, and (2) a reverse incremental checkpointing (RIC) mechanism to handle destination or network failure during post-copy. We present the design, implementation, and evaluation of V-Recover in the KVM/QEMU virtualization platform. Our evaluations show that V-Recover effectively recovers a VM upon migration failure with acceptable overheads on migration metrics and application performance.
Design and Development of SECU Converter Cascaded Control for EV Applications

Abstract A power factor correction-based hybrid converter operating in continuous conduction mode with high efficiency and voltage conversion ratio is presented in this publication. The proposed converter is obtained by integrating the single-ended primary inductance converter (SEPIC) and the Cuk converter to produce a DC symmetrical balanced dual output voltage across the load without a common ground between source and load. The modeling of the converter by state space model is derived using the state space averaging technique. The cascaded control strategy using a multiplier approach with a cascaded controller and PI-Hysteresis-based controller is employed for shaping the source current and load voltage. The performance analysis of the suggested converter under steady state and transient conditions is carried out in MATLAB/Simulink software tool. The observed result displays that cascaded control yields excellent performance compared to PI-Hysteresis control in satisfying the IEC 61000-3-2 standard by maintaining a power factor close to unity, and reduced total harmonic distortion.
A Brief History of Ends/Goals: How Can Goals (Motivation) Emerge from a Goalless World?

This paper will be devoted to the discussion of the concept of goal in human understanding. The scientific discussion of it can be traced back to ancient Greece, where it was called teleology. This triggered a lot of questions: as theories prostrating the universe as uniformed emerged, these types of teleological ideas were attracted by natural philosophers studying determinism: things do not exist to serve a purpose, they exist only because, under the influence of other things in the world, they have to be there. The sun is not there to provide brightness to the world, it was there long before the exitance of the world. Nevertheless, the unsettling problem is that human beings do, a lot of times, think in a goal-directed way, so how to reconcile the fact that no teleological language can explain natural phenomena with the fact that teleological thinking exists in human understanding becomes the million dollar question. Still, there could be a solution, not as straightforward as the problem, but sufficient to demonstrate how goals can emerge from a goalless nature. With the conatus theory as the basis, this paper is going to review how it can be the building block of the nowadays negative feedback loop model and such a model is also a variation of Hume theory of association and passion.
Professional Development Used to Enhance K-5 Teachers’ Competencies Working with English Language Learners

Over the past decade, the United States education system has predicted a significant increase in the number of English Language Learners (ELLs) enrolled in public schools. A substantial number of teachers who interact with ELLs lack the preparedness to support their student’s academic needs. Research has shown that the lack of professional development (PD) debars teachers from receiving efficacious resources to support English Language Learners. Most professional development (PD) provided for teachers excludes addressing ELL’s content. The absence of PD specifically focused on ELLs has left many teachers entering the profession not adequately trained to engage and support ELL students. The types of PD described by teachers tend to give the bare minimum coverage of how to work with ELLs rather than go in-depth on the issues that prohibit ELL students’ ability to understand the learning content. The conceptual framework incorporated in this exploratory research will be Thomas Guskey’s theory of teacher change to focus on the goals of professional development. This exploratory research will examine PD to further understand which delivery modes are optimal to address a major deficit in knowledge regarding PD training that limits teachers’ competencies to understand and support ELLs.
Semiring Reasoning Frameworks in AI and Their Computational Complexity

Many important problems in AI, among them #SAT, parameter learning and probabilistic inference go beyond the classical satisfiability problem. Here, instead of finding a solution we are interested in a quantity associated with the set of solutions, such as the number of solutions, the optimal solution or the probability that a query holds in a solution. To model such quantitative problems in a uniform manner, a number of frameworks, e.g. Algebraic Model Counting and Semiring-based Constraint Satisfaction Problems, employ what we call the semiring paradigm. In the latter the abstract algebraic structure of the semiring serves as a means of parameterizing the problem definition, thus allowing for different modes of quantitative computations by choosing different semirings. While efficiently solvable cases have been widely studied, a systematic study of the computational complexity of such problems depending on the semiring parameter is missing. In this work, we characterize the latter by NP(R), a novel generalization of NP over semiring R, and obtain NP(R)-completeness results for a selection of semiring frameworks. To obtain more tangible insights into the hardness of NP(R), we link it to well-known complexity classes from the literature. Interestingly, we manage to connect the computational hardness to properties of the semiring. Using this insight, we see that, on the one hand, NP(R) is always at least as hard as NP or ModpP depending on the semiring R and in general unlikely to be in FPSPACEpoly. On the other hand, for broad subclasses of semirings relevant in practice we can employ reductions to NP, ModpP and #P. These results show that in many cases solutions are only mildly harder to compute than functions in NP, ModpP and #P, give us new insights into how problems that involve counting on semirings can be approached, and provide a means of assessing whether an algorithm is appropriate for a given class of problems.