Miracle-dz/UniFAR-FTUs huggingface dataset:
Design Aspects of Single-Ended and Differential SiGe Low-Noise Amplifiers Operating Above fmax/2in Sub-THz/THz Frequencies

This article presents a single-stage single-ended (SE) and a multistage pseudo-differential cascode low-noise amplifiers (D-LNA) with their center frequencies at 235 and 290 GHz, respectively. Both low-noise amplifiers (LNAs) are designed beyond half of the maximum frequency of oscillation (<inline-formula> <tex-math notation="LaTeX">$f_{\text {max}}$ </tex-math></inline-formula>) in 130-nm SiGe BiCMOS technology with <inline-formula> <tex-math notation="LaTeX">$f_{t}/f_{\text {max}}$ </tex-math></inline-formula> of 300<inline-formula> <tex-math notation="LaTeX">$/$ </tex-math></inline-formula>450 GHz. Implications of gain-boosting and noise reduction techniques in cascode structure are analyzed and it is observed that beyond <inline-formula> <tex-math notation="LaTeX">${f_{\text {max}}}/2$ </tex-math></inline-formula>, these techniques do not provide desired benefits. The single-stage SE LNA is designed to ascertain the theoretical analysis, and the same analysis is further implemented in staggered tuned four-stage LNA. Single-stage SE LNA provides a small signal gain of 7.8 dB at 235 GHz with 50 GHz of 3-dB bandwidth by consuming 18 mW of power. Four-stage differential LNA gives 12.9 dB of gain at center frequency 290 GHz and 11.2 dB at 300 GHz by drawing 68 mA current from the 2-V supply. The 3-dB bandwidth of differential LNA is measured to be 23 GHz. Noise figure measurements of both LNAs are performed using a gain-method technique with their measured noise figure values of 11 and 16 dB, respectively. This work successfully demonstrates the possibility of using a Si-based process to implement amplifiers beyond <inline-formula> <tex-math notation="LaTeX">$f_{\text {max}}/2$ </tex-math></inline-formula>. To the authors’ best knowledge, the four-stage differential LNA achieves, without any gain-boosting technique, the highest gain at <inline-formula> <tex-math notation="LaTeX">$2/3(f_{\text {max}})$ </tex-math></inline-formula> with decent noise figure performance in SiGe technology.
Détection de sinusoïdes noyées dans du bruit par les régions d'inclusion des valeurs propres

The inclusion regions of the eigenvalues enable us to work out efficient criteria for the estimation of the number of sinuso ids. To exploit those regions, it is necessary first to transform the covariance matrix. That is why we put forward a transformation ba sed on an approximation of the eigenvalues and eigenvectors, so as to obtain the radii and the centres of the Gerschgorin disks, the disk s being the studied inclusion regions. We show that the introduction of information concerning the radii and the centres in the detection c riteria improves their performances tremendously. A new criterion using the Euclidean distance (and called GDE dist) is also suggested.
Primary hydatid cyst of the sternocleidomastoid muscle: Unusual location

Knowledge of the patient’s medical history, occupation and residence can place hydatid cyst among our differential diagnoses. Today, however, the advent of imaging facilities such as ultrasound, CT scan, and magnetic resonance imaging (MRI) has made the diagnosis of hydatid cysts much easier. Floating membranes, daughter cysts, vesicles, and the hydatid sands in purely cystic lesions are well shown on ultrasound. [3] The best modality for diagnosing calcification of the cysts is CT scan. From that side, central nervous system hydatid cysts and complex or solid patterns are well detected by MRI. [4]
Controversies in the dental implant treatment planning for anterior maxillary aesthetic zone – A review

ABSTRACT The anterior maxillary region being an aesthetic zone remains critical in decision-making when it comes to replacing a tooth. Treatment planning to place dental implants in aesthetic zone like anterior maxilla needs paramount attention in order to provide best of the treatment outcomes from aesthetic point of view. As the field of dental implants tend to evolve continuously, newer concepts with inadequate research come into practise on regular basis. In this article, some of the controversies regarding dental implant placement and treatment process related to anterior maxillary aesthetic zone are discussed with literature to support evidence.
Regulation of CD163 Receptor in Patients with Abdominal Aortic Aneurysm and Associations with Antioxidant Enzymes HO-1 and NQO1

Red blood cells are found within the abdominal aortic aneurysm (AAA), in the intraluminal thrombus (ILT), and in neovessels. Hemolysis promotes aortic degeneration, e.g., by heme-induced reactive oxygen species formation. To reduce its toxicity, hemoglobin is endocytosed by the CD163 receptor and heme is degraded by heme oxygenase-1 (HO-1). A soluble form (sCD163) is discussed as an inflammatory biomarker representing the activation of monocytes and macrophages. HO-1 and NAD(P)H quinone dehydrogenase 1 (NQO1) are antioxidant genes that are induced by the Nrf2 transcription factor, but their regulation in AAA is only poorly understood. The aim of the present study was to analyze linkages between CD163, Nrf2, HO-1, and NQO1 and to clarify if plasma sCD163 has diagnostic and risk stratification potential. Soluble CD163 was 1.3-fold (p = 0.015) higher in AAA compared to patients without arterial disease. The difference remained significant after adjusting for age and sex. sCD163 correlated with the thickness of the ILT (rs = 0.26; p = 0.02) but not with the AAA diameter or volume. A high aneurysmal CD163 mRNA was connected to increases in NQO1, HMOX1, and Nrf2 mRNA. Further studies are needed to analyze the modulation of the CD163/HO-1/NQO1 pathway with the overall goal of minimizing the detrimental effects of hemolysis.
Effectiveness of Multicomponent Interventions and Physical Activity in the Workplace to Reduce Obesity: A Systematic Review and Meta-Analysis

Background: Overweight and obesity are public health problems that affects the workplace. This paper aims to analyse the effectiveness of workplace health promotion interventions in reducing Body Mass Index (BMI); Methods: Following PRISMA guidelines, a systematic review was conducted using PubMed, MEDLINE, and SCOPUS databases. The inverse variance statistical method was used for the meta-analysis with a random effects analysis model and standardised means. The results have been represented by Forest Plots and Funnel Plots graphs; Results: The multicomponent approach had the best results for reducing BMI (−0.14 [−0.24, −0.03], 95% CI; p = 0.009) compared to performing physical activity only (−0.09 [−0.39, 0.21], 95% CI; p = 0.56). However, both methods resulted in positive changes in reducing BMI in the general analysis (−0.12 [−0.22, −0.02], 95% CI; p = 0.01). The GRADE evaluation showed low certainty due to the high heterogeneity between interventions (I2 = 59% for overall analysis). Conclusions: The multicomponent approach could be an effective intervention to reduce obesity in the working population. However, workplace health promotion programs must be standardised to conduct quality analyses and highlight their importance to workers’ well-being.
Numeric Abstract Domains Abstract Interpretation Course

ions ECNU, 26–27/11/2013 Numeric Abstract Domains Antoine Miné p. 15 / 132 Numeric semantics Abstractions Numeric abstract domains Representation: given by a set D] of machine-representable abstract values a partial order (D],⊆],⊥],>]) relating the amount of information given by abstract values a concretization function γ: D] → D (D def = P(V→ I)) giving a meaning to each abstract element Required algebraic properties: γ should be monotonic for ⊆]: X ] ⊆] Y] =⇒ γ(X ]) ⊆ γ(Y]) γ(⊥]) = ∅ γ(>]) = V→ I Note: γ need not be one-to-one ECNU, 26–27/11/2013 Numeric Abstract Domains Antoine Miné p. 16 / 132 Numeric semantics Abstractions Numeric abstract domain examples
Evaluation of the Wound Healing Potential of Cynara humilis Extracts in the Treatment of Skin Burns

Cynara humilis is traditionally used to treat skin burns and microbial infections. However, experimental studies on this plant are rare. Furthermore, the aim of this study was to investigate the effects of Cynara humilis, a Moroccan herbal remedy, on the healing of deep second-degree burns in rats with a silver sulfadiazine group. This research was also carried out to confirm if C. humilis had antibacterial capabilities. Under typical burn procedures, each rat received a deep second-degree burn on the upper back. The burns were treated regularly with control groups (control and control VH), silver sulfadiazine (SDD) in group 3, C. humilis ethanolic extract (CHEE) in group 4, and C. humilis aqueous extract (CHAE) in group 5. Throughout the treatment, digital photography was used to measure rat responses to the treatment until day 18. After the scar biopsy at the end of the study, histological parameters (inflammatory cells, collagen, epithelialization, fibrosis, and granulation tissue) were assessed. Using the well technique, the antibacterial activity of the extracts was tested against Staphylococcus aureus CIP 483, Bacillus subtilis CIP 5262, Escherichia coli CIP 53126, Pseudomonas aeruginosa CIP 82118, and Salmonella enterica CIP 8039, and the results showed important activities of the ethanolic and aqueous extracts against the five species tested with MICs of 2 and 4 mg/mL, respectively. In the aqueous extract group, the wound healed faster. In addition, the healing rate in the C. humilis extracts (CHEA and CHEE) group was faster than in the silver sulfadiazine and control groups. In the C. humilis group, maximum wound surface recovery was observed at the same time, as it was not noted in the silver sulfadiazine group. Pathologically, epithelialization was more marked in wounds treated with C. humilis extracts (CHE). Angiogenesis and inflammatory cells were considerably lower in the CHE group than in the silver and other control groups. However, elastic fibers were considerable in the CHE-treated group. In histological examination, the C. humilis group had a low incidence of angiogenesis and inflammation, indicating that this group had less wound scarring. Collagen and burn wound healing were both faster in the C. humilis group. The findings of this study suggest that C. humilis, as indicated by traditional medicine, is a promising natural source for the management of wound healing.
Silencing of LINC00467 inhibits cell proliferation in testicular germ cell tumors cells

A significant decrease in LINC00467 expression in testicular germ cell tumors (TGCTs) was found in our previous study in comparison to adjacent tissue. The expression of LINC00467 correlated with the pathological grade of the tumor in TGCT patients. The higher the expression of LINC00467 was, the worse the prognosis of the patients with TGCT was. Despite these findings, the exact role of LINC00467 in the development of TGCTs requires further investigation. LINC00467 expression was downregulated in the NCCIT and TCam-2 cell lines via small interfering RNA (siRNA) silencing. The levels of gene expression were validated using quantitative real-time polymerase chain reaction (qRT-PCR) analyses. Cell proliferation was evaluated by the MTT and Cell Counting Kit-8 (CCK8) assays, whereas flow cytometry was used to assess the effects on the cell cycle. Western blotting analysis was used to detect expression levels of protein. Additionally, RNA-sequencing and bioinformatics methods were used to investigate the mechanism of action of LINC00467 in TGCTs. The suppression of LINC00467 expression resulted in decreased cell proliferation and induced S-phase arrest. Furthermore, the suppression of LINC00467 downregulated proliferating cell nuclear antigen (PCNA), a protein related to cell cycle regulation, while it upregulated p21 expression. In other studies involving dihydrotestosterone (DHT) stimulation, it was observed that DHT could upregulate LINC00467 expression. In addition, silencing of the LINC00467 reversed the effect of testosterone on cell proliferation. The Gene Set Enrichment Analysis (GSEA) revealed that LINC00467 regulated the p53 pathway by modulating the expression of CCNG1. Our study found that LINC00467 regulates cell proliferation by inducing S-phase arrest through the cell cycle-related proteins PCNA and p21. These findings contribute to our understanding of non-coding RNAs mechanisms involved in the development of TGCTs.
Anomalies in the History of Relativity

In November 1919 it was announced to the world that observa- tions of a solar eclipse that occurred in May 1919 supported Albert Einstein' s general theory of relativity. That announcement was one of the most influen- tial events of 20th-century science, since Einstein' s instant rise to enormous fame arose directly from it. In spite of the confidence with which the an- nouncement was made, however, it was later realized that the accuracy of the observations was insufficient to constitute a reliable confirmation of the phe- nomenon that was predicted. Furthermore, another of the formulas published in the general theory, for the variation in the perihelion of the planet Mercury, had already been derived by another scientist several years earlier using an- other method. In spite of the fact that the experimental evidence for relativity seems to have been very flimsy in 1919, Einstein' s enormous fame has re- mained intact and his theory has ever since been held to be one of the highest achievements of human thought. The resulting deification of Einstein has had some unfortunate effects: critics of his theory are often dismissed as cranks, and the search for better theories has been inhibited. It is suggested that the announcement of the eclipse observations in 1919 was not a triumph of sci- ence as it is often portrayed, but rather an obstacle to objective consideration of alternatives.
Origin of Consciousness and Zero Point Field

Yukawa coupling of scalar fields of Nambu-Goldstone bosons and Dirac fields of electrons creates interference pattern. Nambu-Goldstone bosons emerge from the quantum electric dipole field of the brain triggered by small energy of brain wave. The electrons come from the axons of neurons. The collapse of the interference pattern creates consciousness. This consciousness merge with supreme consciousness which is zero point energy. It has been experimentally proven that zero point energy exists even at absolute zero temperature. The author postulates that this zero point energy not only exists in our universe but also outside the universe and was there even before Big Bang which created our universe. Big Bang theory assumes that universe is created from nothing. Since something cannot be created out of nothing, the author postulates that our universe was created from zero point energy. This zero point energy is the supreme consciousness where our consciousness merges after every event.
Selecting Multiview Point Similarity from Different Methods of Similarity Measure to Perform Document Comparison

Objective: The main objective is to implement multi view point similarity to perform document comparisons that use the concept of clustering. Methods/Analysis: The main task of data mining is clustering which is used to group or select objects which are similar to one another. Data mining divides whole document into meaningful clusters and analyses data. There are many different types of clustering methods like hierarchical clustering, partitioned clustering and data grouping may be based on distance, viewpoints, Euclidean distance etc, Of these, the current system uses single view point similarity. This type of single view point similarity has some disadvantages. The main disadvantage is it does not use full set of document data so that detailed comparison measures cannot be revealed. In the future system multi viewpoint similarity is used to overcome the above disadvantage. Findings: The multi view point similarity method is used to overcome the disadvantages mentioned under the analysis. This method compares similarity between the multiple documents in detailed manner. The documents have been compared line by line and show the similarity. Then we have enhanced the existing ECSMTP algorithm and it is named as ECSMTP (Enhanced Concept Based Similarity Measure for Text Processing). This algorithm categorizes data from selected documents along with weight age of document, and based on that it forms clusters and calculates the similarity measure. Further in this system different kind of documents were compared like text documents, word, PDF documents etc., but it is not in the existing system. User may select kind of document and comparisons can be made on the selected documents. Clusters were formed and these clusters were compared.
Acute Oral Toxicity Test of Antihypertensive Polyherbal Preparations Containing Allium sativum Curcuma aeruginosa & Amomi fructus

Hypertension is a major factor causing atherosclerotic cardiovascular disease, heart failure, stroke, and kidney failure. Polyherbal preparations containing garlic (Aliium sativum), temu ireng (Curcumae aeruginosae) and cardamom (Amomi fructus) have been widely used to treat hypertension. Despite widely used in community, its safety has not been evaluated. This study aimed to evaluate the single dose oral safety of the polyherbal. The acute oral toxicity test was done using fixed dose methods. Single dose of the polyherbal was administered to female Wistar rats. The clinical examination was done after administration of the polyherbal and continued until the 14th day to check for symptoms of toxicity, changes in body weight. On day 15, the animal was sacrificed and histopathological examination was conducted. The body weight did not differ between animal that received polyherbal and not received polyherbal. However, there was an increase in body weight in a group that received polyherbal at a dose of 2000 mg/kg. The absolute and relative organs weight was also similar among groups. There were no macroscopic and histopathological changes in kidney, liver, heart, spleen, aorta, and lungs. The polyherbal preparations containing Aliium sativum, Curcumae aeruginosae and Amomi fructus is safe with LD50 >2000-5000 mg/kg in Wistar rats.
Injurious Fall in an Elderly Chronic Heroin Addict During a Syncopal Episode

The risk factors and related negative outcomes associated with falls in the elderly population have been widely researched. Falls in the elderly population can lead to decreased independence and an increased risk of morbidity and mortality. Concomitant factors that can increase the risks of falls in the elderly include polypharmacy, vision impairment, syncope, hyporeflexia, and drug use. Presented is the case of a 79-year-old African American female who arrived at the emergency department after experiencing a syncopal episode at her home. The episode resulted in a non-fatal injurious fall. This case report examines the relationship between chronic drug use in an elderly patient and its predilection for syncopal episodes, which led to a non-fatal injurious fall.
Plasminogen Activator Inhibitor-1 Potentiates Neutrophil Infiltration and Tissue Injury in Colitis

The mechanism underlying inflammatory bowel disease (IBD) remains unclear. We aimed to identify early diagnostic biomarkers and understand their roles in the pathogenesis of IBD. Methods: We identified plasminogen activator inhibitor-1 (PAI-1) as a potential key gene that is upregulated in IBD based on published transcriptomic datasets. To further determine the role of PAI-1 in disease pathogenesis, we induced colitis in wild-type (WT) and PAI-1 knockout (KO) mice by administering dextran sulfate sodium (DSS). We used an RNA array of genes and 16S rRNA sequencing of the microbiome to analyze PAI-1 function. The colon and serum PAI-1 levels in humans were further evaluated for their diagnostic value. Results: PAI-1 expression was significantly increased in patients and DSS-induced WT mice but reduced in PAI-1 KO mice. These changes were associated with significantly decreased neutrophil infiltration in colonic tissues. The RNA array revealed that the CXC chemokines CXCL1 and CXCL5 and their common receptor CXCR2 were among the most significantly different genes between the PAI-1 KO mice with DSS-induced colitis and the WT mice. Mechanistically, PAI-1 deficiency led to blunted activation of the NF-κB pathway in the colon epithelium. The gut microbiome was altered in the PAI-1 KO mice, which showed enriched abundances of short-chain fatty acid-producing genera and diminished abundances of pathogenic genera. Receiver operating characteristic (ROC) curve analysis revealed the diagnostic value of PAI-1. Conclusions: Our data suggest a previously unknown function of PAI-1 inducing neutrophil-mediated chemokine expression by activating the NF-κB pathway and affecting the function of the gut microbiome. PAI-1 could be a potential diagnostic biomarker and a therapeutic target in IBD.
A Generalized Constraint Model for Two-Dimensional Beam Flexures

To utilize beam flexures in constraint-based flexure mechanism design, it is important to develop a qualitative and quantitative understanding of their constraint characteristics in terms of stiffness and error motions. This paper provides a highly generalized yet accurate closed-form load-displacement model for two-dimensional beam flexures, taking into account the nonlinearities arising from load equilibrium applied in the deformed configuration. In particular, stiffness and error motions are parametrically quantified in terms of elastic, load-stiffening, kinematic, and elastokinematic effects. The proposed beam constraint model incorporates any general loading conditions, boundary conditions, initial curvature, and beam shape. The accuracy and effectiveness of the proposed beam constraint model is verified extensively by non-linear Finite Elements Analysis. © 2009 ASME
Conservative Sparse Neural Network Embedded Frequency-Constrained Unit Commitment With Distributed Energy Resources

The increasing penetration of distributed energy resources (DERs) will decrease the rotational inertia of the power system and further degrade the system frequency stability. To address the above issues, this article leverages the advanced neural network (NN) to learn the frequency dynamics and incorporates NN to facilitate system reliable operation. This article proposes the conservative sparse neural network (CSNN) embedded frequency-constrained unit commitment (FCUC) with converter-based DERs, including the learning and optimization stages. In the learning stage, it samples the inertia parameters, calculates the corresponding frequency, and characterizes the stability region of the sampled parameters using the convex hulls to ensure stability and avoid extrapolation. For conservativeness, the positive prediction error penalty is added to the loss function to prevent possible frequency requirement violation. For the sparsity, the NN topology pruning is employed to eliminate unnecessary connections for solving acceleration. In the optimization stage, the trained CSNN is transformed into mixed-integer linear constraints using the big-M method and then incorporated to establish the data-enhanced model. The case study verifies 1) the effectiveness of the proposed model in terms of high accuracy, fewer parameters, and significant solving acceleration; 2) the stable system operation against frequency violation under contingency.