Miracle-dz/UniFAR-FTUs huggingface dataset:
Implementation of Design Sensitivity Analysis for Nonlinear Elastic Structures

Implementation of design sensitivity analysis into MARC, a general nonlinear finite element code, is described. Follower forces and constraints treated via Lagrange multipliers are also included in the implementation. The sensitivity analysis is implemented in the most general way; i.e., arbitrary design criteria and design parameters including shape, sizing, and material property variables can be defined through special user-supplied subroutines. Local derivatives of all of the quantities needed for sensitivity analysis are calculated using the central differences allowing a very general implementation without sacrificing the accuracy. Design sensitivities to multiple parameters are implemented, even though an option for multiple loading does not apply to nonlinear finite element analysis. Also, design sensitivities can be calculated at any load level, whereas the analysis calculations march on as if there was no interruption. Derivation of design sensitivities with constraints such as incompressibility or unilateral frictionless contact indicates that the same steps, as in the implementation of regular displacement based nonlinear finite element method, can be followed without any modifications. A numerical example using the modified finite element code is presented to demonstrate the new capability.
Proceedings of the XX International Vitamin A Consultative Group Meeting Why Do Children Become Vitamin A Deﬁcient? 1,2

Vitamin A deﬁciency is very prevalent and contributes substantially to morbidity and mortality among young children in developing countries. We identify and quantify three causes of vitamin A deﬁciency in young children based on data available in the literature: maternal vitamin A deﬁciency resulting in low concentrations of vitamin A in breast milk, inadequate dietary intake of vitamin A during and after weaning and prevalent illness. We developed a set of recursive equations to estimate the amount of vitamin A in the liver as a function of age over the ﬁrst 2 y of life. To apply the equations, we selected a best estimate value for each input parameter as the most representative of a typical child in a developing country. Because of the great variability that exists for each variable, we also carried out sensitivity analyses, substituting more extreme values for input parameters. We then estimated stores, assuming a child in a developing country also receives the newly revised vitamin A supplementation regimen recommended by the World Health Organization. Without supplementation, a typical child in a developing country is not able to attain and maintain “minimally adequate” liver vitamin A stores. To overcome this deﬁcit by eating fruits and vegetables alone, the child would need to increase portion sizes about 10-fold. If the child receives the new supplementation regimen, his or her liver stores will still be far short of the average American child (i.e., exceedingly far from toxic levels). However, our estimates indicate that the new supplementation regimen will permit a typical child in a developing country setting to attain minimally adequate vitamin A stores during the ﬁrst 2 y of life. J. Nutr. 132: 2002. In a sensitivity analysis, we assumed the complementary diet begun at 6 mo was similar to that of the 12- to 48-mo-old Indian children studied by Ramakrishnan et al. (24). Using their data, we estimated the intake of 15-mo (450-d)-old children to be the same as that of the 12- to 17-mo-old study children (54 (cid:1) g of RAE/d) and the intake of 1-y (365-d)-old children to be the average of the 18- to 23-mo and the 24- to 29-mo-old children studied (76 (cid:1) g of RAE/d). For f 0 ( t ), we plotted the Indian data and connected the points with straight lines. In the sensitivity analysis examining the effect of partial versus exclusive breast-feeding during the ﬁrst 6 mo of age, we assumed that weaning foods replacing breast milk before 6 mo of age (such as water, porridge, juice and tea) contain negligible amounts of vitamin
Determination of physical and functional properties of orange fleshed sweet potato ( Ipomea batatas L.) flour

Vitamin A deficiency is caused by a habitual diet that provides too little bio available vitamin A to meet physiologic needs. Apart from cheap source of energy, Orange fleshed sweet potato is an excellent source of the β-carotene. This crop is also gaining importance as the cheapest source of antioxidant having several physiological attributes like anti-oxidation, anti-cancer and may help in protection against liver injury and coronary heart disease. Fresh tubers are bulky and perishable, which can be processed into flour and can be used in manufacturing of various value added food products.
Comparison of Beam forming algorithms for better Convergence

- This paper focuses on comparison of a new technique FOUR WAY LMS with Variable step size Normalised least mean square (VSSNLMS) and Normalised least mean square(NLMS) with respect to mean square error for various cases by varying the number of interference users and number of antenna elements. VSSNLMS focuses on varying the step size to avoid a trade-off issue between convergence rate and steady-state Mean Square Error (MSE). Better convergence can be achieved by four way lms algorithm. We here focus on comparison of VSSNLMS (previous approach), NLMS and LMS with FOUR WAY LMS and prove it provides better convergence.
Improving Performance of Variable Speed Wind Turbines using Takagi-Sugeno Fuzzy Controller and LQR Method

: This paper focuses on variable speed wind turbines operation with pitch control. An advanced control strategy is proposed based on linear quadratic regulator and fuzzy controllers in order to improve the performance of the variable-speed wind turbine. The proposed controller is designed to reduce rotor speed variation and optimizing wind turbine power. Wind turbine states are estimated by using fuzzy observer. Moreover, the Takagi-Sugeno fuzzy strategy is used to regulate the rotor speed by controlling the rotation of blades. The proposed method is implemented on MATLAB software by SimWindFarm simulator. Simulation results proved that the fuzzy TS method is appropriate in improving efficiency of wind turbine. Moreover, the proposed method shows better performance compared to the PI controller.
The Inﬂuence of Ions in the Interaction of Methylene Blue with DPPC Membranes

—Methylene blue (MB) and its derivatives have ap- plications as photosensitizers in photodynamic therapy. How-ever, little is known about their interactions with phospholipid membranes at the molecular level. We employed molecular dynamics simulations to model the binding between MB and a dipalmitoyl phosphatidylcholine (DPPC) bilayer. This was done in the presence of molecular oxygen within the membrane. The abitily of MB to induce photodamage was inferred based on its immersion depth and degree of exposition to a higher oxygen concentration inside the membrane. In addition, the effect of the presence of ions in the solvent was explicitly considered.
Detecting Malaria Hotspots: a comparison between RDT, Microscopy and Polymerase Chain

Background: Malaria control strategies need to respond to geographical hotspots of transmission. Detection of hotspots depends on the sensitivity of the diagnostic tool used. Methods: We conducted cross-sectional surveys in three sites within Kilifi County, Kenya, at variable transmission intensities. RDT, Microscopy and PCR testing were used to detect asymptomatic parasitaemia and hotspots were detected using the spatial scan statistic. Results: 8581 study participants were surveyed in three sites. There were statistically significant malaria hotspots by RDT, microscopy and PCR for all sites except by microscopy in one low transmission site. Pooled data analysis of hotspots by PCR overlapped with hotspots by microscopy at a moderate setting but not at two lower transmission settings. However, variations in degree of overlap was noted when data were analysed by year. Hotspots by RDT were predictive of PCR/microscopy at the moderate setting, but not at the two low transmission settings. We observed long-term stability of hotspots by PCR and microscopy except for RDT. Conclusion: Malaria control programmes may consider PCR testing to guide asymptomatic malaria hotspot detection once the prevalence of infection falls.
DMSO_A_289988 505..513

1Department of Psychiatry, Hue University of Medicine and Pharmacy, Hue University, Hue, Thua Thien Hue, Vietnam; 2Preventive Medicine, Hue University of Medicine and Pharmacy, Hue University, Hue, Thua Thien Hue, Vietnam Background and Aims: Depression is common in people with type 2 diabetes mellitus. The association of depression and diabetes has negative effects on patients. This study investigated the prevalence of depression in individuals with type 2 diabetes mellitus and examined the social, psychological and clinical factors associated with depression. Patients and Methods: The study included 216 inpatients with type 2 diabetes mellitus at the Department of Endocrinology and Neurology, Hue Central Hospital and the Department of General Internal Medicine, Hue University Hospital. This descriptive cross-sectional study evaluated depression using the Patient Health Questionnaire-9 (PHQ-9). Data were collected on patients’ socio-demographic factors such as sex, age, marital and economic status, level of education and clinical factors including duration of type 2 diabetes mellitus, fasting blood glucose, HbA1C, comorbidities or complications as well as health behavior including alcohol consumption, smoking and physical activities. Logistic regression was used to analyze the factors associated with depression in patients with type 2 diabetes mellitus. Results: 23.2% of the patients had depression. The rates of severe, moderate and mild depression were 0.5, 0.9 and 21.8%, respectively. Multivariate logistic regression analysis indicated several factors associated with depression in participants, including age under 60 years, poor economic status, unstable or part-time work, having stress during the past year, without/poor treatment adherence to type 2 diabetes mellitus, and engaging in heavy physical activity or physical activity less than three days per week. Conclusion: The prevalence of depression among patients with type 2 diabetes mellitus is high. Endocrinologists should be made aware of the increased risk of depression in this patient population and screening individuals for relevant risk factors is highly recommended.
A Theory of Truth and Semantic Representation

Two conceptions of meaning have dominated formal semantics of natural language. The first of these sees meaning principally as that which determines conditions of truth. This notion has inspired the disciplines of truth theoretic and model-theoretic semantics. According to the second conception meaning is, first and foremost, that which a language user grasps when he understands the words he hears or reads. The two conceptions have remained separated, and the semantic theory presented in this chapter is an attempt to remove this obstacle. The theory combines a definition of truth with a systematic account of semantic representations. The analysis of pronominal anaphora is informed by the conviction that the mechanisms which govern deictic and anaphoric occurrences of pronouns are basically the same. Keywords:anaphoric; language; pronoun; semantic representation; Theory of Truth
Dif ﬁ cult Airway Society 2015 guidelines for management of unanticipated dif ﬁ cult intubation in adults

These guidelines provide a strategy to manage unanticipated dif ﬁ culty with tracheal intubation. Theyare founded on published evidence. Where evidence is lacking, they have been directed by feedback from members of the Dif ﬁ cult Airway Society and based on expert opinion. These guidelines have been informed by advances in the understanding of crisis management; they emphasize the recognition and declaration of dif ﬁ culty during airway management. A simpli ﬁ ed, single algorithm now covers
Association Between Dietary Lutein/Zeaxanthin Intake and Metabolic Syndrome Among U.S. Females: An Analysis of National Health and Examination Years 2015-2018

The prevalence of metabolic syndrome (MetS) is greater among U.S. females than males, mainly due to higher risks of dyslipidemia and hyperglycemia. Lutein and zeaxanthin (L/Z) are carotenoids that can alter the composition of lipoproteins, which may affect components of MetS. However, little is known about the association between L/Z intake and MetS, especially in females. The purpose of this study was to explore the relationship between dietary L/Z or dietary plus supplemental L/Z intakes and MetS in women (n=630), aged 20-50, participating in the National Health and Nutrition Examination Survey 2015-2018. Compared to the lowest quartile, women in the highest quartile of dietary L/Z intake had significantly lower risk of MetS after adjusting for confounders (OR = 0.46; 95% CI: 0.21, 0.98). No significant relationship was noted between dietary plus supplemental L/Z intake and MetS. Future cohort studies should investigate the effects of L/Z on MetS development in women. This study’s sample (n=630) included premenopausal women, aged between 20 to 50 years. As changes in estrogen may affect MetS risk factors, women who were pregnant, breastfeeding, menopausal, and post-hysterectomy were excluded from the overall sample (n=9779) (22). In addition, women with a diagnosis of type II diabetes were not included. Participants who had any of the MetS criteria data missing were also excluded.
A Survey of Anomaly Detection Technique for Credit Default

— Anomaly Detection [1] is the process of classify unusual behavior. It is important data analysis task used for classify interesting and emerging patterns, trends and anomalies from data. Anomaly detection is an important tool to detect irregularity in many different domains including financial fraud detection, computer network intrusion, human behavioral analysis and many more. In today’s era the credit and Loan Default is become high because of many fraudulent activity or increase online purchases. This paper give survey about many technique for anomaly detection in credit or loan default.
Rapid and Simultaneous Detection of bla KPC and bla NDM using Multiplex Real-Time PCR

The increasing incidence of carbapenem non-susceptibility among clinically-important species is 21 of global concern. Identifying the molecular mechanisms underlying carbapenem non- 22 susceptibility is critical for epidemiological investigations. In this report, we describe a real-time 23 PCR based assay capable of simultaneously detecting bla KPC and bla NDM , two of the most 24 important carbapenemases, directly from culture in less than ninety minutes. The assay was 25 validated with bla KPC - and bla NDM -carrying clinical isolates and demonstrated 100% concordance 26 with the CarbaNP test. The potent antimicrobial activity of the carbapenems (ertapenem, doripenem, imipenem, and meropenem) is being increasingly compromised by the emergence and international dissemination of carbapenem-hydrolyzing β -lactamases (carbapenemases) (1-3). Culture-based 31 methods, such as the Modified Hodge test, combined with antibiotic susceptibilities remain the 32 principal method used to detect carbapenemase activity. These methods have limitations, 33 including the inability to differentiate the molecular mechanism involved, extended turnaround 34 times, and inconclusive results, particularly with non- Enterobacteriaceae such as Acinetobacter 35 baumannii and Pseudomonas aeruginosa (4-6). Molecular methods for detecting carbapenemase 36 genes provide several advantages over culture-based techniques including high sensitivity and 37 rapid turnaround time. Furthermore, they provide a critical resource for epidemiological 38 investigations. Despite their advantages, implementation of molecular methods has been slow, 39 primarily due to concerns with allelic variation within target genes, primer cross-reactions, and high costs (7).
e c y D at a in F at ig u in g Is ot on ic E x erc i s e

* T his work w as supported by RRC program of MOST and KOSEF . and DeLuca, 1985), it has been used in the muscle fatigue quantification through the inspection of it s mechanism and validity . T o represent such characteristics of power density spectrum from the fast Fourier transformation (FFT ), the median frequency (MDF ) of equation (1) has been preferred because it is known to be more resistant to noise than the mean frequency (MNF) (Basmajian and DeLuca, 1985; Hof, 1991),(1). N ois e Reduct ion M ethods for the EM G M edian F re quency D at a in F at ig u ing Is otonic E x erc i s e
KEY INFRASTRUCTURE (PKI)

: As Unmanned Aircraft Systems (UAS) are converging an Internet of Things-like infrastructure, always connected to the internet, cryptographic security becomes a primary concern to ensure confidential, but even more importantly tamper-proof transport of data. Another emerging problem is the high number of unregistered drone flights, with no regard towards airspace regulations. The well-established and standardized processes of Public Key Infrastructure (PKI) can be utilized for electronic identification of drones and associating them to the owner, while providing encryption and integrity protection of data. Nowadays various companies provide PKI for drones. This material summarizes the trends, challenges, possibilities of hardware-based on-board secure storage of secrets and describes a possible solution for government-level electronic administration of drones and owners.
ABT-963, A Highly Potent and Selective Disubstituted Pyridazinone COX-2 Inhibitor

Nonsteriodal anti-inflammatory drugs (NSAIDS) are efficacious for the treatment of pain associated with inflammatory disease. Clinical experience with marketed selective COX-2 inhibitors (celecoxib, rofecoxib, and valdecoxib) has confirmed the utility of these agents in the treatment of inflammatory pain with an improved gastrointestinal safety profile relative to NSAID comparators. These COX-2 inhibitors belong to the same structural class. Each contains a core heterocyclic ring with two appropriately substituted phenyl rings appended to adjacent atoms. Here we report the identification of vicinally disubstituted pyridazinones as potent and selective COX-2 inhibitors. The lead compound in the series, ABT-963 (2-(3,4-Difluoro-phenyl)-4-(3-hydroxy-3-methyl-butoxy)-5-(4-methanesulfonyl-phenyl)-2H-pyridazin- 3-one), has excellent selectivity (ratio of 276, COX-2/COX-1) in human whole blood, improved aqueous solubility as compared to celecoxib and rofecoxib, high oral anti-inflammatory potency in vi vo, and gastric safety in the animal studies. Following oral administration, ABT-963 reduced PGE 2 production in the rat carrageenan air pouch model (ED 50 of 0.4 mg/kg) and reduced the edema in the carrageenan induced paw edema model with an ED 30 of 1.9 mg/kg.
On the Stochastic Geometry Modeling and Optimization of Multi-Tenant Network Slicing

—Network virtualization and softwarization techniques are key-enablers of the novel Network Slicing concept. Network slicing introduces new business models such as allowing telecom providers to lease a virtualized slice of their infrastructure to tenants such as industry verticals, e.g. automotive, ehealth, factories, etc. In this paper, regarding this concept, we propose a new analytical framework, based on stochastic geometry theory, to model realistic RANs that leverage the business opportunities offered by network slicing. Moreover, we formulate a 2-Tenant optimization problem in order to optimally allocate transmit power and bandwidth (i.e., a slice of radio access resources) to the users of each infrastructure tenant. Numerical results are illustrated to validate our proposed solution in terms of potential spectral efﬁciency.
A systematic review and meta-analysis of the association between eating disorders and bone density. Osteoporosis , (6), 1953-1966.

Mini Abstract This meta-analysis investigates the effect of an eating disorder on bone mineral density in two eating disorder subtypes. Following conflicting findings in previous literature, this study finds that not only anorexia nervosa, but also bulimia nervosa has a detrimental effect on BMD. Key predictors of this relationship are discussed. Abstract Purpose: This systematic review and meta-analysis investigates bone mineral density (BMD) in individuals with anorexia nervosa (AN) and bulimia nervosa (BN) in comparison to healthy controls (HCs). AN has been associated with low BMD and a risk of fractures and mixed results have been obtained for the relationship between BN and BMD. Deciphering the effect these two ED subtypes on BMD will determine the effect of low body weight (a characteristic of AN) versus the effects of periods of restrictive eating and malnutrition which are common to both AN and BN. Methods: We conducted a systematic search through the electronic databases MedLine, EMBASE and PsychInfo and the Cochrane Library to investigate and quantify this relationship. We screened 544 articles and included 27 studies in a random-effects meta-analysis and calculated the standardised mean difference (SMD) in BMD between women with a current diagnosis of AN (n=785) vs HCs (979) and a current diagnosis of BN (n=187) vs HCs (350). The outcome measures investigated were spinal, hip, femoral neck and whole body BMD measured by DXA or DPA scanning. A meta-regression investigated the effect of factors including age, duration since diagnosis, duration of amenorrhea and BMI on BMD. Results: The mean BMI of participants was 16.65 kg/m ² (AN), 21.16 kg/m ² (BN) and 22.06 kg/m ² (HC). Spine BMD was lowest in AN subjects (SMD, -3.681; 95% CI, -4.738, -2.625; p< 0.0001), but also lower in BN subjects compared with HCs (SMD, -0.472; 95% CI, -0.688, -0.255; p <0.0001). Hip, whole body and femoral neck BMD were reduced to a statistically significant level in AN but not BN groups. The meta-regression was limited by the number of included studies and did not find any significant predictors. Conclusions: This meta-analysis confirms the association between low BMD and AN and presents a strong argument for assessing BMD not only in patients source of funding, geographical location of study, ethnicity of participants, methods, primary outcome measures and key findings were also obtained from each study.
RISK AVERSION AND TECHNOLOGY PORTFOLIOS ECOLE POLYTECHNIQUE

The choice of a portfolio of technologies by risk-averse ﬁrms is analyzed. Two technologies with random marginal costs are available to produce a homogeneous good. If the risks associated to the technologies are correlated ﬁrms might invest in a technology with a negative expected return or conversely might not invest in a technology with a positive expected return. If the technology with the lower expected cost is more risky than the other technology this technology can be driven out of the ﬁrms’ portfolio if risks are highly correlated. With imperfect competition the portfolios of ﬁrms are diﬀerent, and diﬀerence in risk aversion can explain a full specialization of the industry, the less risk averse ﬁrms using the low cost technology and the more risk averse ﬁrms the other one. The framework is used to discuss the issue of investment in electricity markets.