Miracle-dz/UniFAR-FTUs huggingface dataset:
Angiotensin II accelerates functional recovery in the rat sciatic nerve in vivo: role of the AT<sub>2</sub> receptor and the transcription factor NFâ•’ÎoB

The AT2 receptor regulates several functions of nerve cells, e.g., ionic fluxes, cell differentiation, and axonal regeneration, but also modulates programmed cell death. We tested the hypothesis that angiotensin II (ANG II) via its AT2 receptor not only promotes regeneration but also functional recovery after sciatic nerve crush in adult rats. ANG II (10, 10, 10 M) applied locally via osmotic minipumps promoted functional recovery with maximal effects after the lowest concentration. The toe spread distance as a parameter for re-innervation after 20 days was significantly (P<0.01) greater (10.2±10.27 mm) compared with the control group (8.73±0.16 mm). The response to local electrical stimulation (return of sensorimotor function) was reduced to 14.6 days vs. 17.9 days in the control group (P<0.01). The AT2 receptor antagonist PD 123319 administered alone or in combination with ANG II completely prevented the ANG IIinduced recovery, whereas the AT1 receptor antagonist losartan had no effect. Furthermore, ANG II induces, via the AT2 receptor, activation of the transcription factor NF-κB in Schwann cells. Histological criteria, morphometric analyses, and electron microscopy confirmed the functional data. These results are the first to present direct evidence for an involvement of the AT2 receptor and NF-κB in peripheral nerve regeneration.
Specialized robust CFD RANS microscale meteorological model for modelling atmospheric processes and transport of contaminants in urban and industrial areas

State-of-the-art models of dispersion of contamination in the urban environment and industrial areas employ a CFD approach in order to calculate turbulent characteristics of flow around buildings with complex geometry. The main area of application of these models is to facilitate licensing of potentially hazardous facilities and assessment of meteorological conditions in the urban environment. The usage of the most popular commercial CFD software with regard to modelling flows in the urban environment is significantly limited by the requirement for computational mesh refinement near the surface of the building in order to adequately resolve the characteristic scales in the viscous and buffer sublayers. On the other hand, models based on the traditional gaussian approach cannot take into account the complex aerodynamic effects in order to calculate turbulent characteristics of flow around buildings with complex geometry, including the subtleties concerning atmospheric emissions of gas-aerosol substances. Therefore, the authors developed a robust, highly specialized CFDRANS model and a calculation code for modelling the atmospheric dispersion of contamination under conditions of a complex three-dimensional geometry that do not require mesh refinement. The authors verified this model using extensive database obtained both in the course of field experiments as well as of wind tunnel experiments. The verification results showed that the developed model satisfies the acceptance criteria for the quality of modelling along with foreign general-purpose codes and highly specialized codes.
Title : Supplementing small farms with native mason bees increases strawberry size and growth rate

1. Pollination services, especially those of bees, play a vital role in agriculture. Declining honey bee populations require us to find alternative solutions for sustainable agriculture. Native bees are proving to be efficient pollinators. Mason bees (Osmia lignaria) provide valuable pollinator services for some woody orchard species, but their value as pollinators for herbaceous crops is largely untested. 2. We assessed the effectiveness of O. lignaria supplementation on nine strawberry farms over two growing seasons. We specifically selected mason bees for this work because they emerge from cocoons in the springtime, when few other bees are available for pollination. Cocoons are easily deployed on farms and emerged bees have a small flight radius, so they remain localized. We placed cocoons on one side of each berry farm plot (our mason bee addition treatment) but not on the opposite side (our control). We tagged and monitored berries on nine farms throughout the growing season. We performed statistical comparisons of berries from the treatment and control for differences in berry growth rate and size. Additionally, we supplemented farms with native bee homes constructed from three materials (bamboo, Phragmites, and wood). This allowed us to determine whether adult mason bees would produce a subsequent generation of bees on farms, and whether the bees had a preference for nest material type. 3. Our work demonstrates that mason bees can be used successfully to pollinate herbaceous berry crops. We found that berry growth rate was significantly higher and berry volume was significantly larger for berries from the treatment relative to the control. We also found that adult bees successfully utilized the bee homes for laying the A u th o r M a n u s c ri p t
LCLR FILTER DESIGN AND MODELLING FOR HARMONIC MITIGATION IN INTERCONNECTED MICRO GRID SYSTEM

Today many people are attracted towards distribution generation (DG) because of low energy cost power supply, local generation, highly reliable system, supply with good power quality. Increasing attention and investment in renewable energy that is DG energy sources give rise to rapid development of high penetration renewable energy sources like solar energy, wind energy, hydro energy. Out of this most important and best is the solar energy. There are multiple ways to interface PV arrays with the power grid, but in there is problem of power quality. Today’s important concern of the power system is the power quality in case of renewable energy sources. The power quality improvement in the interconnected micro grid systems and grid interconnection with Distribution Generation (DGs) is the challenging task and to overcome the power quality problem passive filters are the best and cost effective solution. In this paper the LCLR filter is implemented between inverter and grid. The complete system consists of photovoltaic cell (PV), DC-DC boost converter, DC-AC inverter, LCLR filter and the grid. This paper also consists of complete MATLAB simulation of PV cell, DC-DC boost converter and inverter with LCLR filter.
DMD 2021-1067 QUANTIFYING POSTURAL INSTABILITY WITH POSE ESTIMATION SOFTWARE AND 3 D DEPTH EXTRACTION

Patients who suffer from Parkinson’s Disease are more prone to postural instability, a major risk factor for falls. One of the most common clinical methods of gauging the severity of a patient’s postural instability is with the retropulsion test [1], in which a clinician perturbs the balance of the patient and then rates their response to the perturbation. This test is subjective and largely based on the observations made by the clinician. In order to improve postural instability diagnosis and encourage more meaningful therapies for this cognitive-motor symptom, there is a clinical need to enable more objective, quantifiable approaches to measuring postural instability. In this paper, we describe a novel computational approach to quantifying the number, length, and trajectory of steps taken during a retropulsion test or other type of balance perturbation from a single camera facing the anterior side (front) of the subject. The computational framework involved first analyzing the video data using markerless pose estimation algorithms to track the movement of the subject’s feet. These pixel data were then converted from 2D to 3D using calibrated transformation functions, and then analyzed for consistency when compared to the known step lengths. The testing data showed accurate step length estimation within 1 cm, which suggests this computational approach could have utility in a variety of clinical environments.
Patents editor in order to automatically construct terminological databases

RÉSUMÉ. Les demandes de brevet ont une structure similaire dans le monde entier. Elles comprennent une page de couverture, un mémoire descriptif, des revendications, des dessins (si nécessaire) et un abrégé. Au monde Arabe, il n’y a pas de collection numérique uniforme de document de brevets et donc pas de collection XML. Dans ce contexte, nous présentons la création d’un modèle de document de brevet standard pour les brevets Arabes et le développement d’un générateur de collection XML de brevets ayant une structure uniforme est simple à utiliser. Cette collection va nous être utile pour la construction d’une base de données terminologique pour les domaines scientifiques et techniques. ABSTRACT. Patent applications are similarly structured worldwide. They consist of a cover page, a specification, claims, drawings (if necessary) and an abstract. In the Arabic world, there is no uniform digital collection of patent documents and therefore no XML collections. In this context, we aim to create a standardized document model for Arabic scientific patents and develop a generator of XML patent collection having a uniform and easy to use structure. This collection will be useful for us to build a terminological database for scientific and technical fields.
Vascular wall dysfunction in JCR:LA-cp rats: effects of age and insulin resistance

Vascular wall dysfunction in JCR:LA-cp rats: effects of age and insulin resistance. Am. J. Physiol. 277 ( Cell Physiol. 46): C987–C993, 1999. —We tested the hypothesis that aging and insulin resistance interact to increase vascular dysfunction by comparing the function of isolated mesenteric resistance arteries in obese, insulin-resistant JCR: LA-cp rats and lean, insulin-sensitive rats of the same strain at 3, 6, 9, and 12 mo of age. The peak constrictor responses to norepinephrine, phenylephrine, and high potassium were elevated in arteries from obese rats. Responses to these agents increased with age in both obese and lean rats. An eicosanoid constrictor contributed substantially to vasoconstriction in the arteries from both lean and obese animals. Inhibition of nitric oxide synthase increased the vasoconstrictor response to norepinephrine in both obese and lean rats. This effect increased with age in lean rats only. Vascular relaxation in response to acetylcholine and sodium nitroprusside was impaired in the obese rats and did not alter with age. The results suggest that obese JCR:LA-cp rats have enhanced maximal constriction, which originates in the arterial smooth muscle and increases with age. There is evidence that the ability of the arteries to compensate for the enhanced contractility is impaired in obese rats, particularly with advanced age.
Activation and inhibition of transient receptor potential <fc>TRPM</fc>3â•’induced gene transcription

EXPERIMENTAL APPROACH We assessed TRPM3-mediated gene transcription, which relies on the induction of intracellular signalling to the nucleus following activation of TRPM3 channels. Activator protein-1 (AP-1) and Egr-1-responsive reporter genes were integrated into the chromatin of the cells. This strategy enabled us to analyse gene transcription of the AP-1 and Egr-1-responsive reporter genes that were packed into an ordered chromatin structure.
RELATIONSHIP BETWEEN FOOD INTAKE AND CARDIOVASCULAR DISEASE IN SOME PATIENTS IN ZAGAZIG, SHARKIA GOVERNORATE

This study was carried out during 2010 -2014 years on 20 cardiac patient subjects. They were random selected from Zagazig University Hospitals in Sharkia Governorate. The patients agreed to participate in the controlled diet study. They were already hospitalized and offered the experimental diet and were followed up completely in the hospital. The experiment was planned in such a way that the daily food taken by patients would confirm to certain specifications. Thus the caloric content of the diet and total fat intake where reduced in addition to a considerable cut down of saturated fat, also the cholesterol content were reduced in the diet. The experimental period lasted 6 months with no dropouts. All patients were advised to avoid certain foods, and not allowed to consume any additional foods. Information on the dietary intake of all individuals collected every day. A follow up of the dietary of all individuals were undertaken for the period of the study in order to study the differences in attitude cards of food before and after the start of the study. The results show that reduce the amount of calories from 262.8 grams/day before the start of feeding to 225.4 grams/day after 6 months of feeding and reduce the amount of intake of animal fat and carbohydrates from 52.2 g/day to 38.6 g / day and 422.6 to 354.8 g/day, respectively, to reduce blood content of triglycerides , cholesterol , LDL and HDL from 240.20, 296.40, 128.30 and 114.20 mg/100 g, respectively, before the start of feeding to 158, 90, 239.25, 86.40 and 112.80 mg / 100 g, respectively. From the results conclude that heart disease linked to nutrition, where the increase in the amount of calories, animal fats saturated and sugar has a significant impact on increasing the concentration of lipids in the blood, and moderate food in the amount of calories and low intake in animal and content of fat on the appropriate amount of unsaturated oils have content a beneficial effect in reducing the proportion of fat in the blood. Saturated fats and oils are considered a serious contributing factor to heart disease.
Robust Component Based Real Time Face Recognition with Occlusion for JPEG Frames

Face recognition is growing in many fields like Biometrics. But it also has some significant challenges for recognizing the face under different illuminations, pose variance, aging, occlusion, facial expression, low resolution etc. Face recognition is practically used in security systems for law enforcement situation at places like boarder security, airports railway station where the identification and verification of person matters a lot especially when face is occluded. This paper is mainly focusing on the Real Time occluded face verification. For this purpose the LPOG technique, which is the combination of BELBP and LPQ will be used. With the help of automatic face detection misalignment algorithm Voila-jones. SSRC the classification technique which is better than other state-of- arts techniques will be used for classification.
Uterine and placental expression of HPGD in cows during pregnancy and release of fetal membranes

Vetsuisse Faculty, University of Zurich, 2017 Jessica von Hof Institute of Veterinary Anatomy, sekretariat@vetanat.uzh. ch Uterine and placental expression of HPGD in cows during pregnancy and release of fetal membranes Abstract: 15-hydroxyprostaglandin dehydrogenase (HPGD) plays a key role in prostaglandins (PGs) catabolism. Its expression and activity appear to be regulated by progesterone (P4). We investigated the HPGD mRNA-expression and protein localization in placentomes and interplacental uterine sites throughout gestation (Study I), and after fetal membranes retention (RFM) compared with normally delivered fetal membranes (DFM) (Study II). Furthermore, we analyzed the influence of aglepristone (AP), dexamethasone (GC) or cloprostenol (CP), on HPGD expression in bovine placentomes (Study III). Tissues from late gestation (D272) and at normal term (NT) served as controls. HPGD was highest in all sites at the beginning of pregnancy and at (NT). Following induced parturition HPGD was lower after (AP) and (GC) compared with (NT), and was similar in RFM and DFM. Placentomes stained primarily in fetal compartments; interplacentomal signals were observed in glandular and luminal epithelium. Results indicate that HPGD may play a role during establishment and termination of gestation.
Dependencies first: Eye tracking evidence from sentence production in Tagalog

We investigated the time course of sentence formulation in Tagalog, a verb-initial language in which the verb obligatorily agrees with one of its arguments. Eye-tracked participants de-scribed pictures of transitive events. Fixations to the two characters in the events were compared across sentences dif- fering in agreement marking and post-verbal word order. Fixation patterns show evidence for two temporally dissociated phases in Tagalog sentence production. The first, driven by verb agreement, involves early linking of concepts to syntactic functions; the second, driven by word order, involves incremental lexical encoding of these concepts. These results suggest that even the earliest stages of sentence formulation may be guided by a language's grammatical structure.
STABILITY CRITERIA OF 3D INVISCID SHEARS

Recent numerical studies in the area of transition to turbulence discovered that the classical plane Couette flow, plane Poiseuille flow, and pipe Poiseuille flow share some universal 3D steady coherent structure in the form of a “streak-roll-critical layer”. As the Reynolds number approaches infinity, the steady coherent structure approaches a 3D limiting shear of the form (U(y, z), 0, 0) in velocity variables. All such 3D shears are steady states of the 3D Euler equations. This raises the importance of investigating the stability of such inviscid 3D shears in contrast to the classical Rayleigh theory of inviscid 2D shears. Several general criteria of stability for such inviscid 3D shears are derived. In the Appendix, an argument is given to show that a 2D limiting shear can only be the classical laminar shear.
PII: S0895-7061(01)02221-X

To examine the role of insulin-like growth factor–1 (IGF-1) in renal atrophy of rats with two-kidney, one-clip (2K1C), in which the clipped kidney atrophies, and in the one-kidney, one-clip (1K1C) model of renovascular hypertension, in which it hypertrophies, we studied levels of IGF-I, mRNA, and protein in 2K1C, 1K1C, and unilateral nephrectomy (NPX) in rats by solution-hybridization RNase protection, and radioimmunoassay, respectively, both cross-reactively and longitudinally at 3, 10, and 30 days after clipping. Three days after clipping, there were no differences in blood pressure or kidney size; however, 10 and 30 days postoperation, the clipped kidney shrank in the 2K1C model. The nonclipped 2K1C and the clipped 1K1C and unilateral nephrectomy kidneys increased in weight (P .05. At day 3 the IGF-I levels were lower (557 54, 335 61 ng/g in control and clipped 2K1C, P .05, v 1074 186, 1109 54, and 1154 200 ng/g kidney, nonclipped 2K1C, 1K1C, and NPX, respectively). At 30 days the IGF-I levels were 300 24 ng/g in control (P .05) v clipped 2K1C, 160 19, 218 20 ng/g in nonclipped 2K1C and 406 33 and 470 34 ng/g in 1K1C and NPX, respectively ( P .05) v control and clipped 2K1C. Kidney mRNA was increased in the clipped 2K1C. In conclusion, the kidney that had higher IGF-I levels early in nonclipped 2K1C, 1K1C, and nephrectomy hypertrophied, and the kidney (clipped 2K1C) that failed to increase IGF-I atrophied. IGF-I levels are dissociated from the local mRNA message. Am J Hypertens 2001;14:1211–1218 © 2001 American Journal of Hypertension, Ltd.
Exploring the relationship between unethical practices, buyer–supplier relationships and green design for sustainability

Abstract Sustainable procurement practices have gained popularity amongst both researchers and supply chain practitioners. However, ethical practices in sustainable procurement have been the topic of discussion in the recent years. The goal of the study is to scientifically build a green procurement framework by exploring relationship between buyer–supplier relationships, unethical practices and green design for sustainability. The study was conducted considering samples from South African steel and engineering sector. Data show high rate of wastages and losses occurring at various stages of steel and engineering supply chains. Every steel and engineering company aims to reduce such losses for improving their profitability and achieve sustainability. The empirical findings show that such wastage and losses can be minimised through efficient eco-design and involvement of key suppliers at the design stage so that disassembly, recycling and reuse options not only prove successful but as well cost-effective for the organisation. Also we find that buyer deceitful practices are a strong determinant of green design for sustainability. Buyers making up a second source of supply for green components and preferring green suppliers being approved by top management is helpful for mitigation of supply risks under green procurement process. The present study is distinctive in terms of coverage and its contribution to supply chain theory.
CMAR_A_253649 4391..4398

Xiao Liu Zhigang Xue Jianchun Yu Zijian Li Zhiqiang Ma Weiming Kang Xin Ye Lin Jiang 1Department of Surgery, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, People’s Republic of China; 2Department of General Surgery, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, People’s Republic of China; 3Graduate School, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, People’s Republic of China Background: Elderly patients with gastric cancer (GC) are at increased risk of infectious complications following gastrectomy. A limited set of risk factors has been identified to predict complications in these patients. To improve the safety of gastrectomy in this population, we investigated the incidence of infectious complications and associated clinicopathologic, nutritional and surgical risk factors in a cohort of elderly patients with GC. Methods: Elderly GC patients (≥70 years) who underwent gastrectomy between January 2013 and December 2017 in Peking Union Medical College Hospital were included in the study. Clinicopathologic data were collected retrospectively. Severity of complications was classified using the Clavien–Dindo system. Infectious complications were assessed based on clinical diagnosis of health care-associated infection as defined by the US Centers for Disease Control and Prevention. Multivariate logistic regression analyses were performed to determine the risk factors for infectious complications. Results: Three hundred thirty-one consecutive patients were included, with a median age of 74 years (range 70–88). The rate of surgical morbidity was 37.5% and the mortality rate was 1.2%. The incidence of infectious complications was 19.6%, with the most common infectious complication being pulmonary infection (11.5%). Preoperative weight loss ≥5% (odds ratio [OR] = 2.21; 95% CI, 1.15–4.28; p = 0.018), Charlson comorbidity index score ≥3 (OR = 2.83; 95% CI, 1.30–6.16; p = 0.009) and preoperative hsCRP level ≥10 mg/L (OR = 2.48; 95% CI, 1.14–5.38; p = 0.022) were independently associated with infectious complications. Conclusion: Preoperative weight loss, elevated hsCRP level and comorbidity burden can be used to predict postoperative infectious complications in elderly GC patients. It is recommended to pay more attention to the treatment of elderly GC patients with these risk factors.
Stem Cell Immunotherapy for HIV Patients and Drawbacks

Stem cell transplantation immunotherapy for HIV emerges since the 1980s. This therapy is can be used to reestablish the immune system of HIV patients. The ultimate goal of stem cell transplantation is clearing the virus from the patient's body. Dominating strategies in this field are combination of gene editing mechanisms with stem cell therapy to develop cytotoxic anti-HIV cells, modify stem cells using artificial and natural stem cell sources etc. Stem cell transplantation with modified zinc finger nuclease might be a promising cure for HIV infection in the future.