Miracle-dz/UniFAR-FTUs huggingface dataset:
Prediction of fluid responsiveness in septic shock patients: comparing stroke volume variation by FloTrac/Vigileo and automated pulse pressure variation

Objectives The aim of this study was to assess and compare the ability of the automatically and continuously measured stroke volume variation (SVV) obtained by FloTrac/Vigileo, and pulse pressure variation (PPV) measured by an IntelliVue MP monitor, to predict fluid responsiveness in mechanically ventilated septic shock patients. Method We conducted a prospective study on 42 septic shock patients. SVV, PPV and other haemodynamic data were recorded before and after fluid administration of 500 ml of 6% hydroxyethyl starch. Responders were defined as patients with an increase in stroke volume index of at least 15% after fluid loading. Results Twenty-four (57.1%) patients were classified as fluid responders. The baseline SVV correlated with the baseline PPV (r = 0.96, P < 0.001). SVV and PPV were significantly higher in responders than in nonresponders (15.5 ± 4.5 vs. 8.2 ± 3.3% and 16.4 ± 5.2 vs. 8.3 ± 3.5, respectively, P < 0.001 for both). There was no difference between the area under the receiver operating characteristic curves of SVV [0.92, 95% confidence interval 0.832–1.00] and PPV (0.916, 95% confidence interval 0.829–1.00). The optimal threshold values in predicting fluid responsiveness were 10% for SVV (sensitivity 91.7% and specificity 83.3%) and 12% for PPV (sensitivity 83.3% and specificity 83.3%). Our results were independent of the site of arterial catheterisation. Conclusion The SVV, obtained by FloTrac/Vigileo, and the automated PPV, obtained by the IntelliVue MP monitor, showed comparable performance in terms of predicting fluid responsiveness in passively ventilated septic shock patients, with a regular cardiac rhythm and a tidal volume not less than 8 ml kg−1.
Lepirudin: is the approved dosing schedule too high?

effective is the DNA-pooling strategy in reducing the number of DNA sequence analyses to be performed. In fact, in a standard single-patient sequencingapproach, the total number of requested sequences isT 1⁄4 N · FwhereN is the number of patients and F the number of fragments to be amplified and sequenced. DNA pooling reduces T (by minimizing unnecessary sequencing of WT fragments) to a value comprised between N + F and 2N + F, depending on the number of heterozygotes in the pool (e.g. if all individuals are homozygous, T 1⁄4 N + F). In the case of four homozygotes, DNA pooling is advantageous for any F bigger than five (e.g. when F 1⁄4 100, a 70% reduction of T is achieved). Obviously, this strategy is recommended only when the chance of large deletions and major chromosomal rearrangements is low. In conclusion, this study widened themutational spectrum of CAF, confirming the heterogeneity of this rare disease. The description of three novel mutations will benefit prenatal diagnosis of CAF, as recently demonstrated in a Palestinian [13] and in two Italian families (S. Duga, unpublished data).
Antibiotic susceptibility patterns of beta-lactamase-producing Escherichia coli and Staphylococcus aureus isolated from chickens in Maiduguri (Arid zone), Nigeria

MAMZA, S. A. , G. O. EGWU, G. D. MSHELIA: Antibiotic susceptibility patterns of beta-lactamase-producing Escherichia coli and Staphylococcus aureus isolated from chickens in Maiduguri (Arid zone), Nigeria. Vet. arhiv 80, 283-297, 2010. ABSTRACT Escherichia coli and Staphylococcus aureus species though opportunist pathogens, are becoming a global clinical problem in both human and veterinary medicine. This study was designed to determine the antibiotic susceptibility patterns of β-lactamase-producing E. coli serotypes and S. aureus strains isolated from chickens in the Maiduguri Arid zone, Nigeria. Various tissue samples from apparently healthy and diseased chickens were collected and examined for the presence of E. coli and S. aureus. Isolates were identifi ed by relevant biochemical tests. β-lactamase-producing strains of the isolates were determined by the chromogenic cephalosporin method, using nitrocefi n-impregnated sticks and cephalosporin (nitrocefi n) solution. The antibiotics susceptibility patterns of the isolates were determined for ten antibiotics (ampicillin, chloramphenicol, cephalexin, ciprofl oxacin, lincomycin, doxycycline, tetracycline, tylosin, tylosin tartrate and penicillin) by the micro-broth dilution method. E. coli was isolated in 805 and S. aureus in 660 of 1300 tissue samples examined; from which 89 (11.1%) and 58 (8.8%) were β-lactamase-positive isolates respectively. Out of 540 E. coli isolates serotyped, 57 (10.6%) serogroups were identifi ed from which 17 (29.8%) were serogroups O1, 5 (8.8%) were O2, and 2 (3.5%), 9 (15.8%), 6 (10.5%) and 18 (31.6%) were serogroups O26, O78, O86 and O141 respectively, whilst, 483 (89.4%) isolates were not typable with the available sera. Serogroups O141, O1 and O78 were more frequently isolated and serogroups O1 and O78 were more prevalent in sick chickens than in healthy chickens. E. coli exhibited high resistance to ampicillin, chloramphenicol, tetracycline, lincomycin, penicillin and tylosin with MIC values >8.0 μg/μL, as did S. aureus to all the antibiotics tested with MIC values >8.0 μg/μL. In conclusion, the study has demonstrated the presence of E. coli serotypes and S. aureus in various tissues of chickens and their antibiotic susceptibility patterns, clearly demonstrating multiple drug resistance.
Euclid flight H2RG IR detectors: per pixel conversion gain from on-ground characterization for the Euclid NISP instrument

Euclid is a major ESA mission for the study of dark energy planned to launch in 2021. Euclid will probe the expansion history of the Universe using weak lensing and baryonic acoustic oscillations probes. A survey of 15,000 deg2 of the sky with the instrument NISP (Near-Infrared Spectro-Photometer), in the 900 – 2100 nm band, will give both the photometric and spectrometric redshifts of tens of millions of galaxies. The 16 H2RG detectors of the NISP focal plane array are still being characterized at CPPM (Marseille). Already 16 out of 20 flight detectors have been tested and a straightforward analysis done. Performance of the dedicated test benches – in particular control of flux and temperature – as well as an overview of the test flow will be presented. This paper will present methods and some preliminary results on two detectors focusing on the determination of a per pixel conversion gain.
Markov Chain Monte Carlo: Stochastic Simulation for Bayesian Inference

Introduction Stochastic simulation Introduction Generation of Discrete Random Quantities Generation of Continuous Random Quantities Generation of Random Vectors and Matrices Resampling Methods Exercises Bayesian Inference Introduction Bayes' Theorem Conjugate Distributions Hierarchical Models Dynamic Models Spatial Models Model Comparison Exercises Approximate methods of inference Introduction Asymptotic Approximations Approximations by Gaussian Quadrature Monte Carlo Integration Methods Based on Stochastic Simulation Exercises Markov chains Introduction Definition and Transition Probabilities Decomposition of the State Space Stationary Distributions Limiting Theorems Reversible Chains Continuous State Spaces Simulation of a Markov Chain Data Augmentation or Substitution Sampling Exercises Gibbs Sampling Introduction Definition and Properties Implementation and Optimization Convergence Diagnostics Applications MCMC-Based Software for Bayesian Modeling Appendix 5.A: BUGS Code for Example 5.7 Appendix 5.B: BUGS Code for Example 5.8 Exercises Metropolis-Hastings algorithms Introduction Definition and Properties Special Cases Hybrid Algorithms Applications Exercises Further topics in MCMC Introduction Model Adequacy Model Choice: MCMC Over Model and Parameter Spaces Convergence Acceleration Exercises References Author Index Subject Index
Randall-Sundrum models vs. supersymmetry: the different flavor signatures

Randall-Sundrum (RS) models and Supersymmetric flavor models provide two appealing solutions to the hierarchy problems of the Standard Model. We introduce the basics of the two frameworks, focusing particularly on the flavor sector. We investigate the possibility to suppress flavor changing neutral current effects thanks to the warped geometry and the custodial protection in the RS model, and to flavor symmetries in Supersymmetry. Having fixed the energy scale of the two frameworks to the TeV range, we study the K and B meson observables (meson mixings and rare decays). We find characteristic patterns of predictions that can allow us to discriminate between the two frameworks, once new data will be available. A particular relevance is attributed to the CP violating asymmetry in the B_s meson mixing system and to the rare decay B_s -> mu+ mu-.
Structural analysis, optical and dielectric function of [Ba0.9Ca0.1](Ti0.9Zr0.1)O3 nanocrystals

This work presents the identification of inter-band transitions in the imaginary part of the dielectric function (e2) derived from the Kramers–Kronig analysis for [Ba0.9Ca0. 1](Ti0.9Zr0.1)O3 (BCZT) nanocrystals synthesized by the modified Pechini method. The analysis started with the chemical identification of the atoms that conform BCZT in the valence loss energy region of a high energy-resolution of electron energy loss spectroscopy. The indirect band energy (Eg) was determined in the dielectric response function. This result is in agreement with the UV-Vis technique, and it obtained an optical band gap of 3.16 eV. The surface and volume plasmon peaks were observed at 13.1 eV and 26.2 eV, respectively. The X-ray diffraction pattern and the Rietveld refinement data of powders heat treated at 700 °C for 1 h suggest a tetragonal structure with a space group (P4 mm) with the average crystal size of 35 nm. The average particle size was determined by transmission electron microscopy.
PENENTUAN BOBOT PERNYATAAN KESEHATAN PESERTA ASURANSI JIWA PEMBIAYAAN SYARIAH MENGGUNAKAN ALGORITMA BACKPROPAGATION (Studi Kasus Asyki Microtakaful)

Asyki Microtakaful (AM) has 5 statements of healthy, all of that healthy statements become a determinant for next process of policy is participant non-medical is potential or no. The process express of potential participant or no are do while underwriting. In the fifth process healthy statement is assessed based on right condition or no. For getting fix assessment then need the weight from all of that statement. The aim from this research is to get the weight from each participant's healthy statement with use closely algorithm back propagation. This research has made new weight from healthy statement, the weight already has compatible with the accuration by the condition healthy statement is ready. The result that we got for network architecture's pattern 5-5-1 (5 input, 5 hidden layer and 1 output) has error's assessment smaller than architecture's pattern 5-3-1 and 5-2-1 with epoch's score maximum 86 then score of mean error (ME) 0.038, mean squared error (MSE) 0.019 and mean absolute percentage error (MAPE) 24.619, input X to Z have the average X1 = -2.27, X2 = 0.32, X3 = - 2.44, X4 = -1.36 and X5 = 0.84 from 35 data.
Ieee Transactions on Visualization and Computer Graphics the Generalized Sensitivity Scatterplot

—Scatterplots remain a powerful tool to visualize multi-dimensional data. However, accurately understanding the shape of multi-dimensional points from 2D projections remains challenging due to overlap. Consequently, there are a lot of variations on the scatterplot as a visual metaphor for this limitation. An important aspect often overlooked in scatterplots is the issue of sensitivity or local trend, which may help in identifying the type of relationship between two variables. However, it is not well-known how or what factors influence the perception of trends from 2D scatterplots. To shed light on this aspect, we conducted an experiment where we asked people to directly draw the perceived trends on a 2D scatterplot. We found that augmenting scatterplots with local sensitivity helps to fill the gaps in visual perception while retaining the simplicity and readability of a 2D scatterplot. We call this augmentation the generalized sensitivity scatterplot (GSS). In a GSS, sensitivity coefficients are visually depicted as flow-lines, which gives a sense of continuity and orientation of the data that provide cues about the way data points are scattered in a higher dimensional space. We introduce a series of glyphs and operations that facilitate the analysis of multi-dimensional data sets using GSS, and validate with a number of well-known data sets for both regression and classification tasks.
Bayesian Optimization for Probabilistic Programs

We outline a general purpose framework for black-box marginal maximum a posteriori estimation of probabilistic program variables using Bayesian optimization with Gaussian processes. We introduce the concept of an optimization query, whereby a probabilistic program returns an infinite lazy sequence of increasingly optimal estimates, and explain how a general purpose program transformation would allow the evidence of any probabilistic program, and therefore any graphical model, to be optimized with respect to an arbitrary subset of its variables.
PREFERENSI GENERASI MILENIAL DALAM MENGGUNAKAN E-WALLET DI KOTA DENPASAR

Penelitian ini bertujuan untuk membuktikan secara empiris pengaruh persepsi kemudahan, persepsi manfaat dan persepsi risiko terhadap minat generasi milenial dalam menggunakan dompet digital. Technology acceptance model digunakan sebagai kerangka teoritis dalam menginvestigasi determinan penerimaan dompet digital. Penelitian ini menggunakan pendekatan kuantitatif yang menyasar pada pengguna dompet digital khususnya generasi milenial. Data penelitian dikumpulkan melalui kuesioner online dengan google form dan menghasilkan sebanyak 145 jawaban responden yang kemudian dianalisis menggunakan SmartPLS. Temuan penelitian mengungkapkan bahwa risiko tidak berpengaruh signifikan terhadap minat generasi milenial menggunakan dompet digital. Sementara faktor persepsi kemudahan dan manfaat yang dirasakan mampu menjelaskan secara signifikan minat generasi milenial menggunakan dompet digital. Persepsi kemudahan memiliki pengaruh paling besar terhadap minat generasi milenial menggunakan dompet digital dibandingkan faktor lain. Penelitian ini menawarkan rekomendasi praktis bagi penyedia dompet digital untuk dapat memahami lebih baik preferensi generasi milenial dan memenuhi harapan mereka.
Film spreading from a miscible drop on a deep liquid layer

We study the spreading of a film from ethanol–water droplets of radii $0.9~\text{mm}<r_{d}<1.1~\text{mm}$ on the surface of a deep water layer for various concentrations of ethanol in the drop. Since the drop is lighter ( $\unicode[STIX]{x1D709}=\unicode[STIX]{x1D70C}_{l}/\unicode[STIX]{x1D70C}_{d}>1.03$ ), it stays at the surface of the water layer during the spreading of the film from the drop; the film is more viscous than the underlying water layer since $\unicode[STIX]{x1D712}=\unicode[STIX]{x1D707}_{l}/\unicode[STIX]{x1D707}_{d}>0.38$ . Inertial forces are not dominant in the spreading since the Reynolds numbers based on the film thickness $h_{f}$ are in the range $0.02<Re_{f}<1.4$ . The spreading is surface-tension-driven since the film capillary numbers are in the range $0.0005<Ca_{f}<0.0069$ and the drop Bond numbers are in the range $0.19<Bo_{d}<0.56$ . We observe that, when the drop is brought in contact with the water surface, capillary waves propagate from the point of contact, followed by a radially expanding, thin circular film of ethanol–water mixture. The film develops instabilities at some radius to form outward-moving fingers at its periphery while it is still expanding, till the expansion stops at a larger radius. The film then retracts, during which time the remaining major part of the drop, which stays at the centre of the expanding film, thins and develops holes and eventually mixes completely with water. The radius of the expanding front of the film scales as $r_{f}\sim t^{1/4}$ and shows a dependence on the concentration of ethanol in the drop as well as on $r_{d}$ , and is independent of the layer height $h_{l}$ . Using a balance of surface tension and viscous forces within the film, along with a model for the fraction of the drop that forms the thin film, we obtain an expression for the dimensionless film radius $r_{f}^{\ast }=r_{f}/r_{d}$ , in the form $fr_{f}^{\ast }={t_{\unicode[STIX]{x1D707}d}^{\ast }}^{1/4}$ , where $t_{\unicode[STIX]{x1D707}d}^{\ast }=t/t_{\unicode[STIX]{x1D707}d}$ , with the time scale $t_{\unicode[STIX]{x1D707}d}=\unicode[STIX]{x1D707}_{d}r_{d}/\unicode[STIX]{x0394}\unicode[STIX]{x1D70E}$ and $f$ is a function of $Bo_{d}$ . Similarly, we show that the dimensionless velocity of film spreading, $Ca_{d}=u_{f}\unicode[STIX]{x1D707}_{d}/\unicode[STIX]{x0394}\unicode[STIX]{x1D70E}$ , scales as $4f^{4}Ca_{d}={r_{f}^{\ast }}^{-3}$ .
Second-order Karush-Kuhn-Tucker necessary conditions in locally Lipschitz vector optimization with inequality constraints

In the present paper, we discuss second-order optimality conditions in constrained vector optimization problems, where the objective functions and active constraint functions are locally Lipschitz at the referee point. By using the second-order upper generalized directional derivative and the second-order tangent set, we introduce a new type of second-order regularity condition in the sense of Abadie. Then we establish some second-order Karush-Kuhn-Tucker necessary optimality conditions in primal form for local (weak, Geoffrion properly) efficient solutions to the considered problem. Examples are given to illustrate the obtained results.
Parameter Adjustment in Gaining Accuracy of Plagiarism Detection

A parameter is a significant variable in determining the calculation result of a method. In Rabin-Karp, several parameters determine the accuracy of this algorithm. The role of the parameter acts as a determinant of the level of similarity of the document. The method ocuuped is Rabin-Karp. It is performed for plagiarism checking. Rabin-Karp works by mapping documents into words (tokenizing). The token formed will be mapped in word snippets (N-Grams) that have the same length. The main parameters that play a role determine the accuracy of similarity, N-Gram, Base, and Modulo. N-Gram length is varied. It is determined based on the target desired. In the modulo section, it uses a specific prime number. N-Gram, Base, and Modulo values have varying results when combined. N-Gram will proceed a Hash calculation that serves to give the value on each piece of the word. The Hash value also depends on the Base and Modulo provided. The combination of these three values determines the accuracy percentage of the document's similarity. The Hash value of both documents generated produces the identical hashes. It is the determinant of the similarity level obtained. The proper combination will improve the calculation accuracy.
Reconstructing Evolving Tree Structures in Time Lapse Sequences by Enforcing Time-Consistency-Appendix

In Section 4, we described briefly how temporal consistency could be enforced by incorporating into the objective function of Eq. 2 a penalty term involving the flow variables used to solve the QMIP problem of Eq. 3. In this Section, we justify the form of this additional term in more detail. We first define the constraints that must be imposed on the flow variables to ensure temporal consistency and then derive the complete objective function accordingly.
The instability of a moving interface in a narrow tapering channel of finite length

We analyse the displacement of one fluid by a second immiscible fluid through a narrow channel of finite length which connects two reservoirs. We assume that the channel width slowly decreases in the direction of flow, and that the fluids have different viscosity and density. We examine the stability of the interface and find that there are Saffman–Taylor and Rayleigh–Taylor type modes, which may dominate in the narrow and wide regions of the channel, respectively. The gradient of the pressure jump across the interface associated with the surface tension acts to stabilise the interface, and for intermediate channel widths, this effect may dominate the destabilisation associated with both the Rayleigh–Taylor and Saffman–Taylor instabilities, provided the rate of change of the channel width with distance along the channel is sufficient. We also note that the effect of the converging channel leads to instability of long-wavelength modes owing to the quasi-static acceleration of the flow through the cell: we consider cases in which this effect only occurs at much lower wavenumbers than the most unstable Saffman–Taylor and Rayleigh–Taylor modes. We show that there is a maximum wavenumber for instability, which varies with position in the channel. By integrating the growth rate of each wavenumber in time as the interface moves across the channel, we predict the mode which grows to the greatest amplitude as the interface traverses the channel.
Cigna Healthcare Coverage Position Subject Transvaginal Ultrasound for Ovarian and Endometrial Cancer Screening or Surveillance Revised Date ............................. 7/15/2007 Original Effective Date ............. 7/15/2005 Coverage Position Number ............. 0398 Table of Contents Hyperlink

INSTRUCTIONS FOR USE Coverage Positions are intended to supplement certain standard CIGNA HealthCare benefit plans. Please note, the terms of a participant's particular benefit plan document [Group Service Agreement (GSA), Evidence of Coverage, Certificate of Coverage, Summary Plan Description (SPD) or similar plan document] may differ significantly from the standard benefit plans upon which these Coverage Positions are based. For example, a participant's benefit plan document may contain a specific exclusion related to a topic addressed in a Coverage Position. In the event of a conflict, a participant's benefit plan document always supercedes the information in the Coverage Positions. In the absence of a controlling federal or state coverage mandate, benefits are ultimately determined by the terms of the applicable benefit plan document. Coverage determinations in each specific instance require consideration of 1) the terms of the applicable group benefit plan document in effect on the date of service; 2) any applicable laws/regulations; 3) any relevant collateral source materials including Coverage Positions and; 4) the specific facts of the particular situation. Coverage Positions relate exclusively to the administration of health benefit plans. Coverage Positions are not recommendations for treatment and should never be used as treatment guidelines. ©2007 CIGNA Health Corporation Coverage Position CIGNA HealthCare covers periodic transvaginal ultrasound screening or surveillance for ovarian and/or endometrial cancer as medically necessary for ANY of the following: • known or suspected hereditary ovarian cancer syndrome (i.e., BRCA1 or BRCA2 mutation) or a substantial likelihood of having a BRCA mutation (i.e., a mutation is known to be present in the family or there is a strong family history of early breast cancer in one or more first-or second-degree † family members) • known hereditary nonpolyposis colon cancer (HNPCC)–associated genetic mutation or a substantial likelihood of having an HNPCC mutation (i.e., a mutation is known to be present in the family) or a family history of ovarian and/or endometrial cancer in one or more first-or second-degree family members • personal history of breast, ovarian, endometrial or an HNPCC-associated cancer † A first-degree relative is defined as a blood relative with whom an individual shares approximately 50% of his or her genes, including the individual's parents, full siblings, and children. A second-degree relative is defined as a blood relative with whom an individual shares approximately 25%