Miracle-dz/UniFAR-FTUs huggingface dataset:
Preparation and characterization of Bomidin-loaded thermosensitive hydrogel for periodontal application

Abstract Periodontitis is a chronic infection and tissue-destructive disease which is considered as the major cause of tooth loss. However, satisfactory clinical treatment for the disease has yet to be achieved. Herein, we designed an injectable thermo-sensitive hydrogel consisting of hydroxypropyl methylcellulose (HPMC), hyaluronic acid (HA) and glycerol (Gl), and further loaded with Bomidin (FP), a recombinant antimicrobial peptide (AMP), the physicochemical and biological characteristics were subsequently investigated in vitro. The results indicated that the prepared hydrogel can be injected and changes phase in situ at desirable temperature. Also, a three-dimensional network structure and cell compatibility were observed. Importantly, the FP-embedded hydrogels exhibited strong antibacterial activities against oral pathogens Porphyromonas gingivalis ( P. gingivalis ), Staphylococcus aureus ( S. aureus ), and Escherichia coli ( E. coli ). These findings indicated our hydrogel possesses not only good fluidity, stable thermosensitivity but also preferable biocompatibility and antibacterial properties, thus demonstrate promising potential for application in periodontal treatment. Trial registration PJ2020-113-001, registration date: Jun 2019. Graphical abstract
Mayfly Ephemeraglaucops (Ephemeroptera, Ephemeridae) recorded in the Czech Republic after almost a century

Abstract Background The mayfly Ephemera (Sinephemera) glaucops Pictet, 1843 has been considered regionally extinct in the Czech Republic, with the last occurrence dating from 1933. Its extinction was connected with the anthropogenic changes of lowland rivers, forming the original habitat of E.glaucops within the area of the Czech Republic. However, the species has been reported as spreading in man-made, often post-industrial waterbodies in Germany, The Netherlands and Austria since the 1970s. New information We report E.glaucops from the Czech Republic, based on 27 larvae collected in the North Bohemia lignite basin in 2018. All individuals were found at one locality – a small kaolin pit in the shallow part near the shore, mostly without macrophytes. We provide details about the locality and morphological diagnostic characters of E.glaucops. This study highlights the importance of post-industrial sites for aquatic biodiversity as surrogate biotopes for degraded original habitats.
Extrinsic models for the dielectric response of CaCu3Ti4O12

The large, temperature-independent, low-frequency dielectric constant recently observed in single-crystal CaCu3Ti4O12 is most plausibly interpreted as arising from spatial inhomogenities of its local dielectric response. Probable sources of inhomogeneity are the various domain boundaries endemic in such materials: twin, Ca ordering, and antiphase boundaries. The material in, and neighboring, such boundaries can be insulating or conducting. We construct a decision tree for the resulting six possible morphologies, and derive or present expressions for the dielectric constant for models of each morphology. We conclude that all six morphologies can yield dielectric behavior consistent with observations. Thus, present experimental findings are insufficient to establish the internal morphology responsible for the remarkable properties of CaCu3Ti4O12, and we suggest further experiments to distinguish among them.
Leaf Cell Morphology Alternation in Response to Environmental Signals in Rorippa aquatica

Heterophylly, the phenomenon by which plants alter leaf forms to adapt to surrounding conditions, is apparent in amphibious plant species. In response to submergence, they emerge leaves with narrower blade areas. The pathway that receives the submergence signals and the mechanism regulating leaf form via cell proliferation and/or expansion systems have not yet been fully identified yet. Our anatomical study of Rorippa aquatica, an amphibious plant that exhibits heterophylly in response to various signals, showed that leaf thickness increased upon submergence; this was caused by the expansion of mesophyll cell size. Additionally, these submergence effects were inhibited under blue-light conditions. The ANGUSTIFOLIA3 (AN3)/GROWTH-REGULATING FACTOR (GRF) pathway regulating cell proliferation and cell expansion was downregulated in response to submergence; and the response was blocked under the blue-light conditions. These results suggest that submergence and light quality determine leaf cell morphology via the AN3/GRF pathway.
Super-Hydrophobic Magnetic Fly Ash Coated Polydimethylsiloxane (MFA@PDMS) Sponge as an Absorbent for Rapid and Efficient Oil/Water Separation

In this study, magnetic fly ash was prepared with fly ash and nano-magnetic Fe3O4, obtained by co-precipitation. Then, a magnetic fly ash/polydimethylsiloxane (MFA@PDMS) sponge was prepared via simple dip-coating PDMS containing ethanol in magnetic fly ash aqueous suspension and solidifying, whereby Fe3O4 played a vital role in achieving the uniformity of the FA particle coating on the skeletons of the sponge. The presence of the PDMS matrix made the sponge super-hydrophobic with significant lubricating oil absorption capacity; notably, it took only 10 min for the material to adsorb six times its own weight of n-hexane (oil phase). Moreover, the MFA@PDMS sponge demonstrated outstanding recyclability and stability, since no decline in absorption efficiency was observed after more than eight cycles. Furthermore, the stress–strain curves of 20 compression cycles presented good overlap, i.e., the maximum stress was basically unchanged, and the sponge was restored to its original shape, indicating that it had good mechanical properties, elasticity, and fatigue resistance.
Note on stability of discrete-time time-varying delay systems

This note is concerned with the problem of delay-dependent stability for discrete-time systems with time-varying delay. Two novel delay-dependent stability conditions are established by bounding the forward difference of the Lyapunov functional based on the reciprocally convex approach and a scale inequality, respectively. These criteria improve the existing ones with smaller computation burden and less conservatism, which is verified by both theoretical proof and a numerical example.
Iatrogenic empyema secondary to the malposition of a nasogastric tube

Blind NGT insertion can lead to tube misplacement into the respiratory tract. This can lead to multiple pulmonary complications including lung injury, pneumothorax, pneumonia, empyema and diaphragmatic injury. We present the case of an 80 year‐old female who required an NGT insertion for severe oropharyngeal dysphagia from an acute stroke. Her admission was complicated by multiple pneumothoraces from repeated insertions, as well as the unusual complication of a recurrent nasogastric feeding‐related empyema requiring multiple intercostal chest drain insertions for drainage. This case highlights the importance of careful NGT insertion and placement with imaging confirmation before use.
Screening Utility of the PHQ-2 and PHQ-9 for Depression in College Students: Relationships with Substantive Scales of the MMPI-3

Abstract We investigated the validity and screening effectiveness of the PHQ-2 and PHQ-9 scores in 229 college students in a cross-sectional design. PHQ associations with Minnesota Multiphasic Personality Inventory-3 internalizing scales suggest PHQ scores are effective screening tools for college students and may aid in effective triage and service needs.
Measurement of the dynamics of plasmons inside individual gold nanoparticles using a femtosecond phase-resolved microscope

We demonstrate a phase-sensitive four-wave mixing microscopy in heterodyne detection to resolve the ultrafast changes of the real and imaginary parts of the dielectric function of single small (<40 nm) spherical gold nanoparticles at the surface plasmon resonance. The results are quantitatively described via the transient electron temperature and density in gold considering both intraband and interband transitions. We find that the effect of interband transitions in the excitation is important to explain not only the magnitude of the measured four-wave mixing, but also its initial dynamics, which is dominated by the formation of hot electrons via Auger electron-hole recombination with 70-fs time constant, much faster than the well-characterized 500-fs electron thermalization dynamics for intraband excitation. This microscopy technique enables background-free detection of the complex susceptibility change even in highly scattering environments and can be readily applied to any metal nanostructure.
The Coronae of AR Lacertae

We observed the coronally active eclipsing binary AR Lac with the High Energy Transmission Grating on Chandra for a total of 97 ks, spaced over five orbits, at quadratures and conjunctions. Contemporaneous and simultaneous EUV spectra and photometry were also obtained with the Extreme Ultraviolet Explorer. Significant variability in both X-ray and EUV fluxes were observed, dominated by at least one X-ray flare and one EUV flare. We saw no evidence of primary or secondary eclipses, but exposures at these phases were short and intrinsic variability compromised detection of any geometric modulation. X-ray flux modulation was largest at high temperature, indicative of flare heating of coronal plasma rather than changes in emitting volume or global emission measure. Analysis of spectral line widths interpreted in terms of Doppler broadening suggests that both binary stellar components are active. On the basis of line fluxes obtained from total integrated spectra, we have modeled the emission measure and abundance distributions. The EUV spectral line fluxes were particularly useful for constraining the parameters of the "cool" (≤2 × 106 K) plasma. A strong maximum was found in the differential emission measure, characterized by two apparent peaks at log T = 6.9 and 7.4, together with a weak but significant cooler maximum near log T = 6.2 and a moderately strong hot tail from log T = 7.6-8.2. Coronal abundances have a broad distribution and show no simple correlation with first ionization potential. While the resulting model spectrum generally agrees very well with the observed spectrum, there are some significant discrepancies, especially among the many Fe L lines. Both the emission measure and abundance distributions are qualitatively similar to prior determinations from other X-ray and ultraviolet spectra, indicating some long-term stability in the overall coronal structure.
Which estimating technique

This paper presents a unified view of the relationship between (1) quantity and (2) price generating mechanisms in estimating individual prime construction costs/prices. A brief review of quantity generating techniques is provided with particular emphasis on experientially based assumptive approaches and this is compared with the level of pricing data available for the quantities generated in terms of reliability of the ensuing prime cost estimates. It is argued that there is a tradeoff between the reliability of quantity items and reliability of rates. Thus it is shown that the level of quantity generation is optimised by maximising the joint reliability function of the quantity items and their associated rates. Some thoughts on how this joint reliability function can be evaluated and quantified follow. The application of these ideas is described within the overall strategy of the estimator's decision - "Which estimating technique shall I use for a given level of contract information? - and a case is made for the computer generation of estimates by several methods, with an indication of the reliability of each estimate, the ultimate choice of estimate being left to the estimator concerned. Finally, the potential for the development of automatic estimating systems within this framework is examined.
Skills Expectations in Cybersecurity: Semantic Network Analysis of Job Advertisements

ABSTRACT Cybersecurity jobs are in demand around the country in response to the rapidly growing number of cyberattacks on businesses and government entities. While there is some consensus on core technical skills needed to fill these positions, many hiring employers are not aware of or deemphasize the importance of soft skills in these positions. Using a semantic network analysis of job advertisements, this study sought to answer two research questions: what are the most critical soft skills cybersecurity employers seek? And how are the soft skills related to the hard skills based on industry expectations? This study reports the analysis of 17,929 cybersecurity job advertisements. Our results found that three categories of soft skills emerged: Knowledge management and systems, big data analytical skills, and teamwork and diversity are all highly sought after. In addition, our study findings reinforce a critical role information system is playing in cyber security.
Analysis of the Shielding Effectiveness of Thin Wire Cages by a Hybrid DGTD-FDTD Method

Thin wire simulation is a typical multiscale problem in time-domain computational electromagnetic methods. This article addresses the shielding effectiveness of thin wire cages, and such models can be attributed to complex thin wire structures with multiwire junctions. The discontinuous Galerkin time-domain method for Maxwell's equations is used in our study, and the one-dimensional finite-difference time-domain method is used to construct the iterative scheme for the thin wire. The thin wire is expressed by the modified telegrapher's equations proposed by Holland. In this article, the mesh size is determined by the wavelength of the electromagnetic wave to be analyzed without considering the radius of the thin wire. There is no physical presence of thin wires in our model, and thin wires are expressed by current elements. The proposed method supports the simulation of arbitrarily oriented thin wires, and the proposed method can easily handle complex wire structures. The calculation efficiency can be greatly improved after avoiding multiscale modeling.
The Impact of the Covid-19 Pandemic Determinants on Selected Agricultural Commodity Prices

The global Covid-19 pandemic is the most notable event that has been affecting our lives since the end of 2019. The ongoing pandemic influenced many sectors, including agriculture and commodity markets. The evolution of selected agricultural commodity prices during the global pandemic of Covid19 is investigated in this paper. The major goal is to determine if the Covid-19 indicators affect the price movements of cocoa, corn, sugar, and wheat. Using the ARDL model, we examined the daily prices of chosen commodities from January 23, 2020, to November 30, 2021. Our results show that the price of corn and wheat was not statistically significantly affected by the Covid-19 pandemic determinants. On the other hand, in the case of cocoa, we observed a negative indirect effect of financial volatility in the long run. Furthermore, in the short-run cocoa prices were negatively influenced by the financial volatility index as well as new daily Covid-19 cases. Besides, sugar prices were affected by the increase in the new confirmed Covid-19 cases and death in the long run. We also found an indirect negative impact of the financial volatility on the sugar prices in the short and long run. Moreover, sugar prices were in the short-run heavily affected by its previous developments as well as by the Covid19 media coverage index.
Balanced Nutritional Knowledge Profile and Stress Factors for Karawang Health Science Students during Pandemic

In 2020, mankind is faced with a pandemic problem. If preventive efforts have been made and the covid-19 virus still infected humans, the last step that can be done against the virus is human immunity. So, efforts to increase immunity need to be done, especially during the pandemic. Immunity is related to optimum nutrition. However, optimal nutrition will not be achieved if the related factors are not achieved as well. Therefore, researchers were interested in conducting research to see the knowledge profile of balanced nutritions and stress level as one of the factors in achieving best nutrition during the pandemic. The aim of this study was to determine the knowledge profile of balanced nutrition and stress levels with a sample of health science students at Unsika (Singaperbangsa Karawang University) during the pandemic. This analysis design was a combination of quantitative and qualitative exploration. It was determined purposively and conducted in November-December 2020. From the results of the inquiry, it is known that the profile picture of balanced nutrition knowledge during the pandemic of Unsika Students; 35% of respondents had less intelligence, 61% of the survey participants had moderate insight, and only 4% had a good one. Based on this experiment, it is also known that students got a lot of information from the internet (websites/ articles/ popular social media). An overview of the stress level of Unsika Students; were 35% of respondents at normal stress level, 14% of the samples had mid stress stage, 27% considered as moderate stress phase, 20% included in severe stress class, and 4% got very heavy stress one. The causes of the stress during the pandemic included a slumping economic situation, due to task deadlines and lack of understanding of learning materials, loneliness, boredom, fear of infection of the virus and other personal reasons.
The Dynamics Explorer Wind and Temperature Spectrometer

The Wind and Temperature Spectrometer, designed to measure the concentration, kinetic temperature, and motion (three mutually perpendicular components of the wind) of the neutral particles, is described, noting that measurements of the concentration and velocity of the ambient thermal ions are also possible. Two of the three wind components, the temperature and the concentration of the dominant constituent, can be measured to an altitude of approximately 650 km; the third component can be measured to about 375 km (estimated). Ion measurements can be taken throughout the orbit. The quadrupole mass spectrometer is the principal sensor for the instrument. Measurements of the zonal and vertical components of the wind are made by interpreting the modulation of the particle stream entering the mass spectrometer, induced by baffles that scan slowly (one vertically and one horizontally) in front of the entrance port of the mass spectrometer.
Formulation and scrutinization of a polyherbal combination containing Berberis aristata, Andrographis paniculata and Thevetia peruviana for its in vitro antioxidant and anti-cancer potential

: Herbal medicines are known for their active potential with high safety profile in humans for various disorders. This study was based on the anticancer potential of three widely used plants in the form of a polyherbal combination, which was designed to assess the antioxidant and cytotoxic potential of a polyherbal combination (2:1:1) and its prepared chitosan nanoparticles. Polyherbal combination was prepared at different ratios of plant extracts. Chitosan nanoparticles were prepared using ionic gelation method. Polyherbal combination (2:1:1) was characterized qualitatively and quantitatively by ultraviolet spectroscopy. The characterization of developed nanoparticles was done by scanning electron microscopy and X-ray diffraction. HepG2 cells were used to assess the cytotoxicity of different polyherbal combinations as well as prepared chitosan nanoparticles while 2, 2-diphenyl-1-picrylhydrazyl assay was performed to assess the antioxidant potential of selected polyherbal combination and its chitosan nanoparticles. Content of berberine, andrographolide and rosmarinic acid in polyherbal combination (2:1:1) was found to be 2.188, 0.472 and 0.264%w/w. Cytotoxicity of different polyherbal combinations (2:1:1, 1:1:1, 1:1:2 and 1:2:1) and its prepared chitosan nanoparticles (2:1:1) against HepG2 cells were found to be at an IC 50 of 13.96, 16.47, 15.20, 16.21 and 15.67 µ g/ml respectively. 2, 2-diphenyl-1-picrylhydrazyl scavenging activity of Polyhebral combination (2:1:1) and its prepared chitosan nanoparticles (2:1:1) showed potent antioxidant potential. The developed Polyherbal combination (2:1:1) and its prepared chitosan nanoparticles was found to possess antioxidant and anticancer potential.
Existence of panmictic Hilsa shad (Tenualosa ilisha) populations from two large river ecosystems in Bangladesh revealed by mitochondrial control region

The present study was undertaken to estimate genetic diversity and reveal population structure of Hilsa shad (Tenualosa ilisha) from two large river ecosystems, the Padma and Meghna of Bangladesh using mitochondrial control region (D-loop region). Fin tissue samples of 60 individuals were collected from the Padma (ChapaiNawabgonj) and Meghna River (Chandpur). DNA was extracted and D-loopof mtDNA was amplified, purified and sequenced. A total of 35 Sequences (15 Sequences from the Padma and 20 Sequences from the Meghna population) were analyzed and 14 haplotypes were detected. Total16 polymorphic sites were identified that included11 singleton sites and 5 parsimony informative sites. These populations showed high haplotype diversity (h) (0.863 in the Meghna and 0.901in the Padma population). We found low nucleotide diversity (Pi) within each population, 0.0058±0.0039 in the Padma to 0.0063±0.004 in the Meghna population. The shared haplotypes among the two populations were identified as 28.57%, and the rest 71.43% were private haplotypes. Estimate of genetic differentiations (Fst) suggest that the Meghna population of Hilsa was closely related to the Padma population (Fst= 0.058, P=0.07). The TCS genealogy showed three main haplotypes separated by three mutational steps and hap_10 might be the most ancestral haplotype by its internal position in the network. All results suggest panmixia in T. ilisha populations between the Meghna and Padma river populations and thus similar management plan could be useful for these two river Hilsa fishery in Bangladesh.
Regional Assessment of Freshwater Ecosystems and Climate Change in North America

1. LAURENTIAN GREAT LAKES AND PRECAMBRIAN SHIELD OF U.S.A. AND CANADA 2. ARCTIC AND SUB-ARCTIC REGIONS OF U.S.A. AND CANADA 3. ROCKY MOUNTAINS IN U.S.A. AND CANADA 4. MID-ATLANTIC AND NEW ENGLAND AREAS OF U.S.A. 5. SOUTHEASTERN U.S.A. AND COASTAL MEXICO 6. PACIFIC COAST MOUNTAINS AND WESTERN GREAT BASIN 7. GREAT PLAINS OF U.S.A. AND CANADA 8. BASIN AND RANGE REGIONS AND ADJACENT ARID AND SEMI-ARID REGIONS OF U.S.A. AND MEXICO
Sistem Pendeteksian Rintangan untuk Kapal Tak Berawak dengan Kombinasi Deteksi Tepi, Transformasi Hough dan Deteksi Saliensi

Kapal tanpa awak yang digunakan untuk berpatroli di perairan pesisir membutuhkan sistem deteksi dan penghindar rintangan yang andal. Hal ini dikarenakan banyak terdapat objek-objek yang dapat menghalangi lajunya kapal di permukaan air. Tantangan dalam pengembangan sistem pendeteksian rintangan berbasis citra bagi kapal tak berawak ukuran kecil adalah performa komputasi yang terbatas. Penelitian dilakukan untuk membuat sebuah sistem pendeteksian rintangan bagi kapal tanpa awak yang akurat dengan proses komputasi yang minimum agar dapat diimplementasikan ke dalam sistem tertanam. Sistem yang dibuat mengkombinasikan deteksi tepi, transformasi Hough dan deteksi saliensi untuk mendeteksi adanya rintangan di atas permukaan air. Dari hasil pengujian didapatkan bahwa performa sistem dapat mendekati kemampuan sistem lain yang lebih kompleks namun belum dapat mengunggulinya. Sistem ini juga diimplementasikan pada sistem tertanam dan menghasilkan kecepatan yang memungkinkan untuk dilakukan pengimplementasian secara real-time.