Miracle-dz/UniFAR-FTUs huggingface dataset:
Systematic review on post-stroke computerized cognitive training: Unveiling the impact of confounding factors

Background Stroke is a highly incapacitating disease that can lead to disabilities due to cognitive impairment, physical, emotional, and social sequelae, and a decrease in the quality of life of those affected. Moreover, it has been suggested that cognitive reserve (patients’ higher levels of education or having a skilled occupation), for instance, can promote faster cognitive recovery after a stroke. For this reason, this review aims to identify the cognitive, functional, and behavioral effects of computerized rehabilitation in patients aged 50 years or older who had a stroke, considering cognitive reserve proxies. Methods We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analysis—PRISMA, and performed the search for peer-reviewed randomized controlled trials without a date restriction on CINAHL, LILACS, PubMed, Scopus, and Web of Science databases were chosen. Results We screened 780 papers and found 19 intervention studies, but only 4 met the inclusion criteria and shared data. These studies included computerized tools for motor and cognitive rehabilitation in the experimental groups. In all studies, computerized training was combined with other interventions, such as standard therapy, occupational therapy, and aerobic exercises. There were 104 participants affected by ischemic or hemorrhagic stroke, predominantly male (57.69%), and all with cognitive impairment. Conclusion Despite a limited number of studies, varied methods and insufficient information available, schooling as a CR proxy combined with high-intensity computerized cognitive training was key to mediating cognitive improvement. The systematic review also identified that the associated ischemic stroke and shorter time of onset for rehabilitation contribute to the cognitive evolution of patients. Findings do not support a greater benefit of computerized cognitive training compared to conventional cognitive therapies. Systematic review registration [https://www.crd. york.ac. uk/prospero/display_record. php? RecordID=296193], identifier [CRD42022296193].
Multiple relaxases contribute to the horizontal transfer of the virulence plasmids from the tumorigenic bacterium Pseudomonas syringae pv. savastanoi NCPPB 3335

Pseudomonas syringae pv. savastanoi NCPPB 3335 is the causal agent of olive knot disease and contains three virulence plasmids: pPsv48A (pA), 80 kb; pPsv48B (pB), 45 kb, and pPsv48C (pC), 42 kb. Here we show that pB contains a complete MPFT (previously type IVA secretion system) and a functional origin of conjugational transfer adjacent to a relaxase of the MOBP family; pC also contains a functional oriT-MOBP array, whereas pA contains an incomplete MPFI (previously type IVB secretion system), but not a recognizable oriT. Plasmid transfer occurred on solid and in liquid media, and on leaf surfaces of a non-host plant (Phaseolus vulgaris) with high (pB) or moderate frequency (pC); pA was transferred only occasionally after cointegration with pB. We found three plasmid-borne and three chromosomal relaxase genes, although the chromosomal relaxases did not contribute to plasmid dissemination. The MOBP relaxase genes of pB and pC were functionally interchangeable, although with differing efficiencies. We also identified a functional MOBQ mobilization region in pC, which could only mobilize this plasmid. Plasmid pB could be efficiently transferred to strains of six phylogroups of P. syringae sensu lato, whereas pC could only be mobilized to two strains of phylogroup 3 (genomospecies 2). In two of the recipient strains, pB was stably maintained after 21 subcultures in liquid medium. The carriage of several relaxases by the native plasmids of P. syringae impacts their transfer frequency and, by providing functional diversity and redundancy, adds robustness to the conjugation system.
CONVOLUTIONS OF RAMANUJAN SUMS AND INTEGRAL CIRCULANT GRAPHS

There exist several generalizations of the classical Dirichlet convolution, for instance the so-called A-convolutions analyzed by Narkiewicz. We shall connect the concept of A-convolutions satisfying a weak form of regularity and Ramanujan sums with the spectrum of integral circulant graphs. These generalized Cayley graphs, having circulant adjacency matrix and integral eigenvalues, comprise a great amount of arithmetical features. By use of our concept we obtain a multiplicative decomposition of the so-called energy of integral circulant graphs with multiplicative divisor sets. This will be fundamental for the study of open problems, in particular concerning the detection of integral circulant graphs with maximal or minimal energy.
Low-frequency ultrasound irradiation increases paclitaxel-induced sarcoma cells apoptosis and facilitates the transmembrane delivery of drugs

Sarcoma is a malignant tumor derived from interstitial tissues and requires comprehensive treatment including chemotherapy. Paclitaxel (PTX) is an active agent against sarcoma, but its effect is not sufficiently acceptable and needs to be improved. Low-frequency ultrasound (LFU) has been documented to improve the efficacy of drugs by inducing reversible changes in membrane permeability; however, the effects of the combined use of LFU and PTX for sarcoma tumors remain unclear and warrant further investigation. We investigated the effects of 30 kHz LFU treatment combined with PTX on sarcoma cells A-204 and HT-1080 by analyzing in vitro apoptosis and cell growth inhibition rates, and determined their antitumor effects by examining tumor weights with or without LFU in the S180 sarcoma xenograft model. Drug concentrations in the subcutaneous tumors were measured using high performance liquid chromatography (HPLC). LFU combined with PTX significantly induced cell apoptosis, and blocked the cell cycle of sarcoma cells in G2/M phase, and furthermore, inhibited the activation of JAK2/STAT3 signaling pathway. Meanwhile, LFU combined with PTX inhibited the expression of PD-L1 in vitro, suggesting the potential of enhanced antitumor immunity by this treatment. LFU combined with PTX significantly inhibited the growth of S180 tumors transplanted subcutaneously in Institute of Cancer Research (ICR) mice, and its enhanced effect may be associated with increased local concentrations of PTX in tumor tissues in vivo, with no significant adverse subsequences on body weight observed. We conclude that the combination of LFU and PTX has synergistic antitumor effects and is a candidate for subcutaneous treatment of sarcoma by further increasing the intracellular concentration of PTX.
The effect of audit team’s emotional intelligence on reduced audit quality behavior in audit firms: Considering the mediating effect of team trust and the moderating effect of knowledge sharing

Reduced audit quality behavior is widespread in the auditor’s practice and is an important factor threatening audit quality. Some prior studies have investigated the relationship between auditors’ psychological contract violation and reduced audit quality behavior. However, the research of relationship between emotional intelligence (EI) and auditors’ behavior is still in its infancy despite the fact that the auditing profession would benefit greatly from improving audit team’s EI. This study examines whether and why the audit team’s EI restrains the audit quality reduction behavior in audit firms. In the study, our hypotheses are tested using a data set collected from 326 respondents in Chinese audit firms. The results are as follows: firstly, audit team’s EI is directly negatively related to reduced audit quality behavior. Secondly, EI is indirectly related to reduced audit quality behavior, through team trust. The results of structural equation modeling (SEM) indicate a mediation model where team trust is negatively related to reduced audit quality behavior. Thirdly, knowledge sharing is a significant mechanism that moderates the effects of different types of EI on audit quality reduction behavior. In the audit team with high knowledge sharing, the audit team’s EI can refrain the audit quality reduction behavior; In the audit team with low knowledge sharing, the audit team’s EI has no significant effect on audit quality reduction behavior. This study expands the factors affecting audit quality to the psychological level of audit teams, enriches the literature on audit team’s behavior characteristics, and provides direct evidence for the relationship between audit team’s psychological characteristics and audit quality.
Genetic evidence of differential dispersal pattern in the Asiatic wild dog: Comparing two populations with different pack sizes

Introduction Dispersal is a multi-causal, crucial life-history event in shaping the genetic and behavioral structure of mammals. We assessed the dispersal pattern of dholes aka Asiatic wild dog (Cuon alpinus), a social monogamous mammal at two tiger reserves of Maharashtra with different degrees of pack size and competition with tigers i.e. Tadoba-Andhari (TATR, smaller pack size, higher tiger density) and Nawegaon-Nagzira (NNTR, larger pack size, lower tiger density). Methods We used the microsatellite data of 174 individual genotypes (98 males and 67 females) to assess the dispersal pattern of dholes from two populations with varying pack size, tiger density, and landscape connectivity using gene flow as a proxy. We compared the population structure, pairwise F statistics, assignment index, and relatedness across a spatial scale. Results and discussion Overall, the results suggested a difference in sex-bias dispersal pattern for the two sub-populations, exhibiting significant results for female-biased dispersal in the TATR population with a smaller pack size and higher tiger density. Our study highlights the variability in sex-biased dispersal patterns in two different populations which could be the consequence of different variables such as pack size, tiger density, and geographical scale. The study warrants further quantitative investigation including several factors such as individual behavior, pack composition, pack size, tiger density, etc. In the present Anthropocene era, determining the sex bias in dispersal patterns for a short-range, pack-living carnivore will help in devising an effective conservation management plan for their long-term survival.
Effect of Substrate Temperature on Electrical Properties of BiFeO3 Thin Films Prepared by Sputtering Method

Pure BiFeO3 thin films with different substrate temperatures (600°C and 650°C) were prepared using sputtering method on Pt /Ti /SiO2 /Si(111) substrates. X-ray diffraction analysis reveals that no second phases existed and the structure changed with different substrate temperatures. According to the SEM results, the surface configuration of the BFO film was improved when sputtered at a lower temperature. The P-E curves show a well-shaped hysteresis loop for both BFO films. The spontaneous polarization of two films deposited at 600°C and 650°C is 56 μc/cm2 and 72 μc/cm2 respectively when measured at room temperature.
The effect of clouds on atmospheric absorption of solar radiation

It has long been an issue of whether clouds enhance or reduce atmospheric absorption of solar radiation. Radiative transfer calculations show that the effect of clouds on atmospheric absorption of solar radiation depends strongly on the solar zenith angle, cloud height and surface albedo. Over wide ranges of these parameters, clouds have the effect of reducing atmospheric solar heating. This result can be altered if the cloud specific absorption is amplified by a factor of =40 beyond what has been determined by in situ aircraft measurements. Since there is no observational evidence to support such strong absorption, the excess cloud absorption, if it occurs, can only be explained by some unknown factors other than the cloud specific absorption. 21 refs., 2 figs., 2 tabs.
Stochastic modelling of disability insurance in a multi-period framework

Abstract We propose a stochastic semi-Markovian framework for disability modelling in a multi-period discrete-time setting. The logistic transforms of disability inception and recovery probabilities are modelled by means of stochastic risk factors and basis functions, using counting processes and generalized linear models. The model for disability inception also takes IBNR claims into consideration. We fit various versions of the models into Swedish disability claims data.
Opleiding Informatica Impact of Flow Anonymization on Cyberattack Detection in IoT

Intrusion Detection Systems (IDS) are crucial in networking as they can detect malicious intent that other mechanisms such as firewalls fail to recognize. A technique commonly used in an IDS to detect malicious intent is the use of flow data. However, flow data often contains personal identifiers such as IP addresses that can be considered privacy-sensitive. The privacy sensitivity of these fields makes it hard to share these logs in settings such as collaborative intrusion detection systems (CIDS) or open-source threat intelligence models. This paper will assess how an IDS in an IoT setting performs when privacy is taken into consideration using various anonymization techniques, this is examined in both a binary setting and a multi-class setting with multiple attack types. We show that when we consider the sensitivity of data in a multi-class setting, the F1 score of our best baseline model drops by 12.46% when applying binning anonymization and 22.47% when applying the more conservative black-marker anonymization. Subsequently, in the binary classification setting, we show that anonymization has only a slight effect, with F1 scores dropping 2.90% when applying binning anonymization and 5.46% when applying black-marker anonymization.
Enabling Enterprise Blockchain Interoperability

—In recent years, with the advances made in technology overall, there is a need to modernize the processes currently in place, especially in governmental organizations. This increases the number of different blockchain infrastructures that need to interact with each other, this is the reason that blockchain interoperability is so important and is a problem that needs to be solved for adoption to continue. In this document, we will study blockchain technology, as a possible ﬁt as a solution for existing issues in these systems. A comparison between available blockchain infrastructures is shown to evaluate its applicability in real-world scenarios. We also have a comparison between the different interoperability solutions available, to be able to come to an appropriate solution regarding blockchain interoperability. The solution proposed in this thesis leverages blockchain technology to replace the current paper support model in place for Bills of Exchange with a digital model focused on the integrity and security of the data handled by the system, which is guaranteed by blockchain technology. Our solution is deployed using a blockchain infrastructure, Hyperledger Fab-ric, with nodes representing the multiple institutions involved. Interoperability between these systems is handled with resort to Hyperledger Cactus creating a network of relayers between the multiple blockchain infrastructures interacting. During our evaluation, we achieved a throughput of 114 TPS with an average latency of 0.15 seconds which shows that our solution would be capable of supporting the use of the current bills of exchange system. Regarding our interoperability solution, we have concluded that Cactus offers great ﬂexibility for diverse interoperability use cases, and provides a direct way to further improve its compatibility, while in some niche use cases there might be better solutions that is the trade-off we are committing to by using Cactus.
Commissive Speech Acts of Persuasion in English Political Discourse

: Politics is a process of making decisions by the distribution of power and resources in order to put certain political, economic, and social ideas into practice. For political messages to be delivered to the target community through political discourse, many strategies have been employed to fulfill the purpose of persuading the audience. The study investigates the Commissive speech acts of persuasion utilized in Hillary Clinton and Donald Trump’s 2016 presidential election speeches. Adopting the speech act theory by Searle (1980), the study aims to uncover the features of Commissive speech acts used by the two politicians for persuasion. The data was analyzed using descriptive qualitative method basing on quantitative information. The findings showed that the process of manipulation of the two politicians was fostered by Commissive speech acts, highlighting the illocutionary forces of threatening, pledging, offering, and refusing. Through the illocutionary forces, both Trump and Clinton would like to communicate their different political stands and ideologies to persuade the audience to advocate them. Donald Trump spread his persuasion with more dominating frequencies of Commissive speech acts than Hillary Clinton. Besides, they also demonstrated distinctively different illocutionary acts addressing different issues to serve their political purposes.
Strategies for computing goal‐oriented a posteriori error measures in non‐linear elasticity

We investigate the characteristics and performance of goal‐oriented a posteriori error measures for a class of non‐linear elasticity models, while restriction is made to small strain theory. The chosen error measure of the displacement field can be global or local (probing the chosen quantity in a specific spatial point). The error is computable with the aid of the solution of a dual problem whose data depend on the error measure. The main thrust of the paper is to evaluate the performance of a few different approximation strategies for computing the dual solution. The chosen strategies are compared in terms of accuracy, ease of implementation, reliability and cost‐efficiency. A well‐known numerical example, the Cook's membrane, is used for the numerical evaluations. Copyright © 2002 John Wiley & Sons, Ltd.
La représentation coadjointe du groupe affine

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A Review of Recent Investigations on Flow and Heat Transfer Enhancement in Cooling Channels Embedded with Triply Periodic Minimal Surfaces (TPMS)

Triply periodic minimal surfaces (TPMS) have shown better mechanical performance, mass transfer, and thermal conductivity than conventional and strut-based structures, which have been employed in different disciplines. Most of the literature investigates different TPMS topologies in cooling channels to enhance thermal performance due to the smooth curvature and large surface area. However, a deeper investigation of the effects of TPMS design variables and the thermal performance advantages of cooling channels is required. This review details the effects of TPMS design variables, i.e., porosity, wall thickness, and unit cell size, on flow and heat transfer enhancement. It is found that varying the design variables significantly changes the flow and heat transfer characteristics. Also, by comparing TPMS and conventional cooling structures, it is found that most TPMS structures show better thermal performance than other strategies. Moreover, different fabrication methods for TPMS-based cooling channels in recent investigations are collected and discussed. In light of the reviewed literature, recommendations for future research suggest that more experimental and numerical studies on the flow and heat transfer for different cooling applications are needed. Therefore, this review serves as a reference tool to guide future studies on the flow and heat transfer of TPMS-based cooling channels.
Strict LMI conditions for stability, robust stabilization, and H/sub /spl infin// control of descriptor systems

This paper presents new linear matrix inequality (LMI) conditions for stability, robust stabilization, and H/sub /spl infin// control of linear time-invariant descriptor systems. The conditions are expressed in terms of definite LMIs with no equality constraint, which are much more tractable and reliable in numerical computation than existing conditions, that is, definite LMIs with equality constraints or semidefinite LMIs. Using the results of this paper, we can analyze and design descriptor systems in the almost same way as in the case of state-space models, while sophisticated manipulations are needed to derive the new results.
Forearm Flexor Tendon Injury in Adolescent Athletes: Risk Factors, Treatment, and Prevention

Abstract Injury to the flexor pronator mass is a common condition that is especially prevalent in overhead throwing athletes. The increasing incidence of these injuries has promoted considerable efforts in research to better understand the pathology, risk factors, and potential mechanisms to prevent injury in these athletes. While there are numerous intrinsic and extrinsic factors associated with injury, a common theme involves chronic overuse and microtrauma with inadequate resting intervals between performances. The purpose of this review is to discuss medial elbow injuries in young athletes with a particular focus on the flexor pronator mass.
A Steadier Hand: The First Human Clinical Trial of a Single-Use Robotic-Assisted Surgical Device for Cochlear Implant Electrode Array Insertion

Objective To evaluate the safety and utility of an investigational robotic-assisted cochlear implant insertion system. Study Design Prospective, single-arm, open-label study under abbreviated Investigational Device Exemption requirements. Setting All procedures were performed, and all data were collected, at a single tertiary referral center. Patients Twenty-one postlingually deafened adult subjects that met Food and Drug Administration indication criteria for cochlear implantation. Intervention All patients underwent standard-of-care surgery for unilateral cochlear implantation with the addition of a single-use robotic-assisted insertion device during cochlear electrode insertion. Main Outcome Measures Successful insertion of cochlear implant electrode array, electrode array insertion time, postoperative implant function. Results Successful robotic-assisted insertion of lateral wall cochlear implant electrode arrays was achieved in 20 (95.2%) of 21 patients. One insertion was unable to be achieved by either robotic-assisted or manual insertion methods, and the patient was retrospectively found to have a preexisting cochlear fracture. Mean intracochlear electrode array insertion time was 3 minutes 15 seconds. All implants with successful robotic-assisted electrode array insertion (n = 20) had normal impedance and neural response telemetry measures for up to 6 months after surgery. Conclusions Here we report the first human trial of a single-use robotic-assisted surgical device for cochlear implant electrode array insertion. This device successfully and safely inserted lateral wall cochlear implant electrode arrays from the three device manufacturers with devices approved but he Food and Drug Administration.