Miracle-dz/UniFAR-FTUs huggingface dataset:
Fosfopéptido de caseína-fosfato de calcio amorfo más cepillado con un dentífrico fluorurado en la remineralización de caries incipiente

ANTECEDENTES: El fosfopéptido de caseína-fosfato de calcio-amorfo (CPP-ACP) promueve la remineralización dentaria; sin embargo, las evidencias clínicas de la lesión cariosa inicial son limitadas.OBJETIVO: Comparar el efecto preventivo y remineralizante del CPP-ACP en goma de mascar y crema.MATERIALES Y MÉTODOS: Ensayo clínico efectuado en estudiantes de 11 a 13 años, con duración de tres meses. Se incluyeron superficies de premolares y molares permanentes: libres de caries y con lesiones cariosas incipientes. Los participantes se distribuyeron al azar a tres grupos: a) goma de mascar con CPP-ACP; b) crema con CPP-ACP y c) control. Además, se cepillaron los dientes con un dentífrico que contenía fluoruro de sodio. Para la evaluación, un clínico, quien desconocía los tratamientos aplicados (ciego simple), utilizó el método de fluorescencia laser (DIAGNOdent® Kavo). Se calcularon la mediana y cuartiles de los datos y se aplicaron las pruebas de Kruskall-Wallis, U de Mann-Whitney y Wilcoxon.RESULTADOS: Se estudiaron 90 estudiantes de 11 a 13 años, durante tres meses. Se incluyeron 971 superficies de premolares y molares permanentes: 843 libres de caries y 128 con lesiones cariosas incipientes. Se encontró una disminución en los valores de fluorescencia. Las medianas de las diferencias entre el valor basal y después de cada tratamiento en dientes sin caries fueron: goma de mascar: -2 (-5.0); crema: -1(-3.1) y control: -1(-3.1) p = 0.001. Para los dientes con lesiones incipientes, las medianas fueron: goma: -15(-19,-2), crema: -10(-14,-5) y control -10(-16,-4) con diferencias significativas entre el grupo de goma con el de pasta y control (p = 0.001). CONCLUSIÓN. El fosfopéptido de caseína-fosfato de calcio-amorfo más el cepillado con un dentífrico fluorurado propició la remineralización y la limitación del avance de las lesiones cariosas incipientes, con una mayor eficacia para la goma de mascar.PALABRAS CLAVE: Fosfopéptido de caseína-fosfato de calcio amorfo; CPP; ACP; lesión cariosa; goma de mascar; estudiantes; premolar; molar.
Étude théorique et numérique des équations différentielles stochastiques rétrogrades

Dans un premier temps, nous etudions une nouvelle classe d'equations differentielles stochastiques retrogrades (notees EDSRs) qui sont reliees a des conditions de Neumann semi-lineaires relatives a des phenomenes ergodiques. La particularite de ces problemes est que la constante ergodique apparait dans la condition au bord. Nous etudions l'existence et l'unicite de solutions pour de telles EDSRs ergodiques ainsi que le lien avec les equations aux derivees partielles et nous appliquons ces resultats a des problemes de controle ergodique optimal. Dans une deuxieme partie nous generalisons des travaux de P. Briand et Y. Hu publies en 2008. Ces derniers ont prouve un resultat d'unicite pour les solutions d'EDSRs quadratiques de generateur convexe et de condition terminale non bornee ayant tous leurs moments exponentiels finis. Nous prouvons que ce resultat d'unicite reste vrai pour des solutions qui admettent uniquement certains moments exponentiels finis, ces moments etant relies de maniere naturelle a ceux presents dans le theoreme d'existence. Nous ameliorons aussi la formule de Feynman-Kac non lineaire prouvee par P. Briand et Y. Hu. Enfin, nous nous interessons a la resolution numerique d'EDSRs quadratiques markoviennes dont la condition terminale est bornee. Nous estimons dans un premier temps des bornes deterministes sur le processus Z. Nous donnons ensuite un nouveau schema de discretisation en temps dont la particularite est que la grille de discretisation est non uniforme. Enfin nous obtenons une vitesse de convergence pour ce schema. Par ailleurs, quelques simulations numeriques permettent d'etudier l'efficacite de notre nouveau schema dans un cadre pratique.
The Efficacy of Sedation Depends on the Diet of Population

Physicians are often faced with the fact that the duration of anesthesia varies in different patients, which significantly complicates the process of surgical intervention and may confront the surgeon with an unforeseen situation. Re-cently, publications have appeared in the literature on the effects of various, including exotic products on anesthesia. There are also many conflicting statements about the effect of camel milk (CM) on the duration of anesthesia. Some data show that CM prolongs anesthesia, while other scientists argue the exact opposite: CM shortens the effect of the anesthetic. We decided to shed light on these studies by analyzing the effect of CM consumption on the ef-fectiveness of local anesthesia in different patients. This article highlights the significant changes that occur in anesthesia due to the patients’ diet. To achieve the set goal, we sort the twenty patients underwent local anesthesia into groups depending on duration of local anesthesia in the experimental and control groups. When milk was consumed before the use of analgesics in these two different groups, it changed exactly the opposite: for those who usually drink milk, it was shortened, and for those who did not drink it daily, lengthened. Thus, we found that the differences in the statements of scientists about the CM impact on anesthesia are based on the fact of different effects of CM in its single and long-term use. We attribute this to the suppression under long-term use of CM the cytochrome system neutralizing both foreign compounds and nu-trients entering the organ. However, further long-term studies with larger sample sizes are needed to elucidate the molecular mechanisms behind this phenomenon.
On the friction stir welding of alloy AA2014 under n-MQL cooling condition

Abstract Friction stir welding (FSW) of AA2014 alloy requires cooling to prevent the dissolution of precipitates. The sustainable minimum quantity lubrication technique with graphene nanofluid is employed in this study for cooling purposes. FSW was carried out at 1200 rpm and 72 mm/min. A tool with a square pin was used. The microstructural evolution of the FSW joint under uniaxial tensile load is explored in detail for the first-time using electron backscatter diffraction. The results show that the grains undergo discontinuous dynamic recrystallisation during FSW and continuous dynamic recrystallisation during tensile deformation. Pole figures reveal the shear texture formed by plastic deformation. Tensile deformation has reduced local grain misorientation remarkably and thereby the dislocation accumulation. A significant increase of 94.5% is observed in grain size. Tensile deformation transforms a significant number of sub-grains with low-angle grain boundaries into stable grains with high-angle grain boundaries. The stable recrystallized grains with HAGBs and subgrains with LAGBs significantly influence the mechanical properties of the weld.
A NEW DECISION MODEL FOR CROSS-DOCKING CENTER LOCATION IN LOGISTICS NETWORKS UNDER INTERVAL-VALUED INTUITIONISTIC FUZZY UNCERTAINTY

Cross-dock has been a novel logistic approach to effectively consolidate and distribute multiple products in logistics networks. Location selection of cross-docking centers is a decision problem under different conflicting criteria. The decision has a vital part in the strategic design of distribution networks in logistics management. Conventional methods for the location selection of cross-docking centers are insufficient for handling uncertainties in Decision-Makers (DMs) or experts’ opinions. This study presents a modern Multi-Criteria Group Decision-Making (MCGDM) model, which applies the concept of compromise solution under uncertainty. To address uncertainty, Interval-Valued Intuitionistic Fuzzy (IVIF) sets are used. In this paper, first an IVIF-weighted arithmetic averaging (IVIF-WAA) operator is used in order to aggregate all IVIF-decision matrices, which were made by a team of the DMs into final IVIF-decision matrix. Then, a new Collective Index (CI) is developed that simultaneously regards distances of cross-docking centers as candidates from the IVIF-ideal points. Finally, the feasibility and practicability of proposed MCGDM model is illustrated with an application example on location choices of cross-docking centers to the logistics network design.
VIRTUALISING AN OTTOMAN FORTRESS – LASER SCANNING AND 3D MODELLING FOR THE DEVELOPMENT OF AN INTERACTIVE, IMMERSIVE VIRTUAL REALITY APPLICATION

Abstract. “A picture is worth a thousand words”: a famous quote about knowledge dissemination but also literally true. The documentation of cultural heritage (CH) monuments is carried out by measurements and photos and stored in 3d models – not by textual information alone. So what could be a more straightforward way to inform the public about CH than visual information? This approach can be extended not only by providing static images or videos from predefined angles but by giving the user the opportunity to interactively explore the virtual representation and interact with the scene. Recent advances in contemporary Virtual Reality (VR) have made it available to more people as prices have dropped. New devices have entered the market so that VR is not limited to VR labs, but is available even at home. With modern head-mounted displays the user can immerse himself in the virtual CH monument to explore and interact with it. Game engines offer tools for rapid development of interactions and help to produce visually appealing worlds.In this paper is presented the generation of a virtual 3D model of Rumeli Hisarı, an Ottoman fortress at the Bosporus in Istanbul, Turkey (Fig. 1) and its processing for data integration into the game engine Unity. The project has been carried out as a co-operation between BİMTAŞ, a company of the Greater Municipality of Istanbul, Turkey and the Photogrammetry & Laser Scanning Lab of the HafenCity University Hamburg, Germany with the aim of a VR application for an immersive and interactive visualisation of the fortress using the VR system HTC Vive. The workflow from data acquisition to VR visualisation, including the necessary programming for navigation, is described. Furthermore, the possible use (including simultaneous multiple users environments) of such a VR visualisation for a CH monument is discussed.
Perspective on radiation effects in nanoscale metal–oxide–semiconductor devices

This article provides a brief overview and perspective on the radiation response of nanoscale metal–oxide–semiconductor (MOS) devices. MOS total-ionizing-dose (TID) response is affected strongly by size scaling and the migration from planar to three-dimensional architectures. Radiation-induced charge trapping in isolation oxides and/or charge transport from surrounding materials are critical to the TID response of nanoscale MOS devices. As transistor dimensions and operating voltages have decreased, single-event effects due to cosmic rays and high-energy protons in space and neutrons in terrestrial environments have become increasingly significant to the radiation response of MOS devices. However, nanoscale MOS transistors are essentially immune to ion-induced gate rupture at normal operating voltages. Single-particle interactions will become even more important for future, ultimately scaled MOS devices used in classical and quantum computing applications.
Impact of Feed Low-Protein Diets During Starting Period of Diets Fortified with Amino Acids on Productive Performance and Blood Parameters of Broiler Chickens

The purpose of this study was to examine how broilers' blood profiles and growth performance responded to dietary additional amino acid supplementation on a diet low in protein throughout the starter period. One hundred sixty 1-day-old, unsexed broiler chicks were divided into five groups at random, each with four replications and eight chicks per pen floor. The first group was fed a basal diet (the control group: T1), the second treatment was fed the basal diet (BD) after fasting for 24 h (T2), the third treatment was fed BD supplemented with high level of lysine 12.9 g/kg (T3), the fourth treatment was fed BD supplemented with lysine, methionine and threonine requirements of 13.7, 6.38 and 8.9 g/kg of diet, respectively (T4). The fifth treatment was fed BD supplemented with lysine, methionine, threonine, and valine requirements of 14.7, 6.8, 9.9, and 10.4 g/kg of diet, respectively (T5). Growth performance parameters and blood parameters were measured. ) there were significant differences in live body weight (LBW) and body weight gain (BWG) between the T1, T2 and the other treatments (T3, T4 and T5) which supplemented with amino acid and the highest LBW were observed in T5. there were no significant differences in the plasma levels of total protein, albumin, AST, uric acid, T 3 , T 4 , IgM and IgG between amino acid-supplemented group and the control. The present outcomes show that extra amino acid supplements to the low– protein diet during the start period have improved chickens’ performance.
Association of Serum IgG Antibody to P. gingivalis and Early Chronic Kidney Disease in Diabetics and Non-Diabetics with Periodontitis

Background: Diabetes and Periodontitis share a bidirectional relationship. Hyperglycaemia and duration of diabetes can cause the micro-organisms to thrive in the periodontium leading to the activation of the innate i mmune system and cause low grade infla mmation leading to systemic diseases such as Chronic Kidney Disease (CKD). The co mmonly used markers of CKD are Serum Creatinine and Albumin. Antibodies like IgG have been found to be elevated with decreased Kidney Function which is also elevated in infla mmatory conditions like Diabetes and Periodontitis. As there are no studies done to detect the progression of diabetes and periodontitis to early chronic kidney disease stages by using IgG antibody titre against P. gingivalis as a biomarker. The present study evaluated the same. Methods: Patients were divided into the following group two Groups of 40 each; Group 1 Periodontitis without diabetes) and Group 2 (Periodontitis with Diabetes). Periodontal parameters were recorded. Serum Creatinine, urine albumin and estimated Glomerular Filtration Rate (eGFR) were calculated in both the groups. Serum IgG antibody titre against P. gingivalis was detected using ELISA. Results: IgG antibody titre against P. gingivalis was detected in both groups with no statistical significance (p-value 0.166). eGFR were significantly (p-value-0.007) lower in diabetics with Periodontitis compared with non-diabetics with periodontitis. A significant (p-value-0.002) association was found when IgG antibody against P. gingivalis compared with eGFR in both the groups. Serum Creatinine and urine albumin were significantly higher [p value- 0.001 and p-value- 0.040] in diabetics with Periodontitis compared to non-Diabetics with Periodontitis. Conclusion: IgG antibody titre against P. gingivalis was similar in both the groups with no significant difference but it was associated with decreased eGFR which revealed that IgG antibody titre against P. gingivalis may be used to detect the progression of diabetes to Early chronic kidney Disease Stages. Hence more studies are required to establish it as a potential marker in diabetic patients with periodontitis.
Efficiency of Several Cytochrome P450 Biomarkers in Highlighting the Exposure of Daphnia magna to an Organophosphate Pesticide

The cytochromes P450 (CYP450) represent a major enzyme family operating mostly in the first step of xenobiotic detoxification in aquatic organisms. The ability to measure these CYP450 enzymes’ activities provides a crucial tool to understand organisms’ response to chemical stressors. However, research on CYP450 activity measurement is still limited and has had variable success. In the present study, we optimize, compile, and compare existing scientific information and techniques for a series of CYP450 biomarkers (EROD, MROD, ECOD, APND, and ERND) used on Daphnia magna. Additionally, we explored these CYP450 biomarkers’ activities through the first 5 days of life of daphnids, providing a link between their age and sensitivity to chemicals. In the experiment, daphnids were exposed to an organophosphate pesticide (diazinon) from birth to measure the molecular response of the detoxification process. Our results suggest EROD as the most applicable biomarker for organisms such as D. magna, with a higher organophosphate detoxification rate in daphnids that are 2 and 5 days old. Additionally, a larger body size allowed a more accurate EROD measurement; hence, we emphasize the use of 5-day-old daphnids when analyzing their detoxification response.
Compact wide band directional antenna using cross‐slot artificial magnetic conductor (CSAMC)

In this article a novel wide‐band artificial magnetic conductor (AMC) based wideband directional antenna is presented for ultra‐wideband (UWB) applications. The proposed novel cross‐slot AMC (CSAMC) achieves wide ±90° reflection phase bandwidth of 4.07 GHz (44.69%) and is used as a reflector. The overall antenna structure is designed with 4 × 4 CSAMC unit cell array and has very compact size of (0.584λ0 × 0.584λ0). The proposed structure improves the radiation properties and exhibits 91.5% (3.13‐8.41 GHz) impedance bandwidth (VSWR ≤2). Additionally, it results in significant improvement in gain and front to back ratio. The proposed antenna is fabricated and its measured performance is in good agreement with simulation results.
The effect of the substitution of fishmeal with mealworm (Tenebrio molitor) on the survival, growth and quality of the European seabass (Dicentrarchus labrax) reared in Morocco

1. Polydisciplinary Faculty of Larache, Abdelmalek Essaadi University, Tetouan, Morocco. 2. Aqua M'Diq Company, Port of M'Diq. M'Diq, Morocco. 3. Faculty of Science and Technology of Tangier, Abdelmalek Essaadi University, Morocco. 4. Specialized Center in Zootechnics and Marine Aquaculture Engineering. National Institute of Fisheries Research. M'Diq, Morocco. 5. Hassan 2 Agronomic and Veterinary Institute, Agadir Campus, Morocco. 6. Department of Biology, Faculty of Sciences, Abdelmalek Essaadi University, Morocco. 7. Centre Specialized in Aquatic Animal Pathology. National Institute of Fisheries Research. Tangier, Morocco. Corresponding Author: hchairi@uae.ac. ma
Fatigue Crack Growth Study and Remaining Life Assessment of High Strength and Ultra High Strength Concrete Beams

This paper presents the details of crack growth study and remaining life assessment of concrete specimens made up of high strength concrete (HSC, HSC1) and ultra high strength concrete (UHSC). Flexural fatigue tests have been conducted on HSC, HSC1 and UHSC beams under constant amplitude loading with a stress ratio of 0.2. It is observed from the studies that (i) the failure patterns of HSC1 and UHSC beams indicate their ductility as the member was intact till the crack propagated up to 90% of the beam depth and (ii) the remaining life decreases with increase of notch depth (iii) the failure of the specimen is influenced by the frequency of loading. A ``Net K'' model has been proposed by using non-linear fracture mechanics principles for crack growth analysis and remaining life prediction. SIF (K) has been computed by using the principle of superposition. SIP due to the cohesive forces applied on the effective crack face inside the process zone has been obtained through Green's function approach by applying bi-linear tension softening relationship to consider the cohesive the stresses acting ahead of the crack tip. Remaining life values have been have been predicted and compared with the corresponding experimental values and observed that they are in good agreement with each other.
Methodologies and Wearable Devices to Monitor Biophysical Parameters Related to Sleep Dysfunctions: An Overview

Sleep is crucial for human health from metabolic, mental, emotional, and social points of view; obtaining good sleep in terms of quality and duration is fundamental for maintaining a good life quality. Over the years, several systems have been proposed in the scientific literature and on the market to derive metrics used to quantify sleep quality as well as detect sleep disturbances and disorders. In this field, wearable systems have an important role in the discreet, accurate, and long-term detection of biophysical markers useful to determine sleep quality. This paper presents the current state-of-the-art wearable systems and software tools for sleep staging and detecting sleep disorders and dysfunctions. At first, the paper discusses sleep’s functions and the importance of monitoring sleep to detect eventual sleep disturbance and disorders. Afterward, an overview of prototype and commercial headband-like wearable devices to monitor sleep is presented, both reported in the scientific literature and on the market, allowing unobtrusive and accurate detection of sleep quality markers. Furthermore, a survey of scientific works related the effect of the COVID-19 pandemic on sleep functions, attributable to both infection and lifestyle changes. In addition, a survey of algorithms for sleep staging and detecting sleep disorders is introduced based on an analysis of single or multiple biosignals (EEG—electroencephalography, ECG—electrocardiography, EMG—electromyography, EOG—electrooculography, etc.). Lastly, comparative analyses and insights are provided to determine the future trends related to sleep monitoring systems.
Utilização de VANT na Avaliação da Suscetibilidade a Movimentos de Massa em Áreas de Expansão Urbana do Município de Rio Piracicaba-MG

: This work aims to evaluate the slopes stability located in urban expansion zones at Rio Piracicaba - Minas Gerais, to determine their mass movements susceptibility. The region has an outbreaks history, especially translational landslides, with a planar rupture surface. An unmanned aerial vehicle (UAV) were used to model the terrain in a GIS (Geographic Information System), associated a geological-geotechnical tests and physical and resistance parameters (cohesion and friction angle) of local soil, with the objective of slope stability analysis in areas whose high declivity criteria combined with human occupation, especially in the sections composed by informal settlements. The slopes were subjected to computer rupture simulations, obtaining their relative safety factors, in the saturated soil condition (most unfavorable), verifying the occurrence high susceptibility areas to mass movements, requiring mitigatory or corrective procedures, by the managing authorities, in order to guarantee the inhabitants safety and passers-by.