Miracle-dz/UniFAR-FTUs huggingface dataset:
Voicing relationality: the nature connectedness of young Finnish adults in the promotion of sustainability

Abstract The contemporary planetary multi-crisis can arguably be attributed to the failure of humans’ relationship with nature. Reconnecting humans with nature is therefore a crucial lever for the sustainability transformation and to achieve the long-term well-being of both humans and nature. While nature connectedness (NC) has been studied quantitatively using various measures and scales, there is a need to complement this work with qualitative research that broadens and deepens the understanding of this phenomenon. This article is a qualitative inquiry into NC among 29 unemployed young adults (aged 20–29) in Finland. The data were collected in group interviews and it is noteworthy that the respondents lived in cities, since urbanites are often represented as disconnected from nature. The participants’ discourse on nature is analyzed with the help of a typology of NC constructed on the basis on three NC typologies found in recent research. NC’s linkage to a relational, multi-dimensional, and need-based conceptualization of well-being is also discussed, as is whether NC should be conceived of as a separate need category. All six dimensions of the typology of NC used in the analysis (material, cognitive, experiential, sensual/emotional, philosophical/spiritual, and compassion, care and commitment) could be detected in the respondents’ accounts. The article closes with a discussion of the implications of such manifestations of NC for promoting sustainability.
Space-Mapping Based Automatic Design of SIW-Based Directional Coupler With Arbitrary Power Ratio

In this paper, an automatic design method allowing efficient design of substrate integrated waveguide (SIW) directional coupler with any given power ratio between 3 dB and 20 dB has been proposed. Due to excessive electromagnetic (EM) simulation time of SIW structure, the space mapping technique is exploited to accelerate the design process. An EM-simulation based dielectric rectangular waveguide (RWG) model acts as the surrogate to reduce the simulation time. A two-stage optimization scheme including a differential evolution (DE) algorithm and a Nelder-Mead (NM) simplex algorithm is used to obtain initial surrogate design. Suitable objective functions are proposed for surrogate optimization and for parameter extraction procedure of space mapping technique. Our proposed method is verified with an X band SIW directional coupler with four different power ratio designs, which are 3 dB, 10 dB, 15 dB and 20 dB. The experimental results confirm the effectiveness and efficiency of the method.
Current Perspectives on Nucleos(t)ide Analogue Therapy for the Long-Term Treatment of Hepatitis B Virus

Abstract The hepatitis B virus (HBV) infection remains a global public health problem. This review presents updated recommendations for the optimal current treatment of choice with nucleos(t)ide analogues (NA). Current clinical practice guidelines on the management of chronic hepatitis B (CHB) by the Asian Pacific Association for the Study of the Liver, the European Association for the Study of the Liver and the American Association for the Study of Liver Diseases have been considered. Patients with chronic HBV infection are at increased risk of liver disease progression to cirrhosis and hepatocellular carcinoma (HCC) development. The main goal of therapy is to improve survival preventing disease progression and HCC. The induction of long-term suppression of HBV replication represents the main endpoint of current treatment strategies, while hepatitis B surface antigen (HBsAg) loss is the optimal endpoint. The typical indication for treatment requires elevated HBV desoxyribonucleic acid (DNA), elevated alanine aminotransferase and/or at least moderate histological lesions, while all cirrhotic patients with detectable HBV DNA should be treated. The long-term administration of a potent NA with high barrier to resistance, ie, entecavir, tenofovir disoproxil fumarate or tenofovir alafenamide, represents the treatment of choice. However, HBsAg seroclearance is anecdotal with NA. Treated patients should be monitored for therapy response, adherence, risk of disease progression, and risk of HCC development. This review aims to assess the evolving trends on the potent NA and the new perspectives on finite therapy.
Identification of model and grid parameters for incompressible turbulent flows

The present thesis studies the behavior of turbulence models for incompressible flows based on the DLR-THETA-code and calibrates relevant model and grid parameters arising in the numerical simulations. Large-eddy simulation (LES) is a popular approach dealing with the turbulent flow governed by the Navier-Stokes equations (NSE). Due to the requirement of high resolution of the near-wall region at high Reynolds number flow hybrid approaches, e.g. detached-eddy simulation (DES) and wall modeled LES, are developed to use LES model in separated flow region and Reynolds averaged Navier-Stokes (RANS) model or wall functions in the near-wall region. In LES large scales are resolved and the effect of small scales are modeled, while only mean values are solved in RANS. The model and grid parameters are often flow type dependent and affected by the numerical schemes, e.g. the constant Cs in the Smagorinsky subgrid-scale (SGS) model and the location y(1) of the first grid point away from the wall. The parameter identification problems for incompressible turbulent flow using an adjoint optimization approach are still open. As an alternative the least-square fitting combining a Newton-type method is used to compute the optimized parameter.The DLR-THETA-code is a solver for incompressible flow of finite volume method on collocated grids using projection method. The Smagorinsky SGS model and hybrid methods are implemented into this code. Three benchmark problems with increasing complexity, decaying homogeneous isotropic turbulence (DHIT), plane channel flow and flow over a backward-facing step, are considered. The performance of discretization schemes are first tested with DHIT using the Smagorinsky SGS model. The model parameter Cs is identified with the schemes which provide best results in comparison with the experimental data. Further numerical results are presented for plane channel flow at moderate Reynolds number Re=395 based on friction velocity and channel half width and the grid parameter y(1) is another quantity to identify by comparing the results with the DNS data. For DES based on the Spalart-Allmaras model (SADES), DHIT and plane channel flow at moderate Reynolds number Re=395 are reconsidered. The influence of the model constant in SADES is demonstrated. Moreover, the channel flow at a higher Reynolds number Re=4800 is studied with two hybrid approaches, i.e. LES and SADES with wall functions, that is, wall functions are used to provide approximate boundary condition for the outer layer flow instead of resolving the near-wall region. A correction to the turbulent viscosity in the near-wall region is considered. Finally first results of the instantanous velocity for flow over a backward-facing step are shown.
The role of convexity in the corner enhancement effect, in visual short-term memory, in perception of symmetry, and in shape interference

Contour curvature information has been shown to have an impact on the visual perception of shape. We have conducted studies on perception of convexity and concavity in relation to memory and attention. Previous studies (Badcock & Westheirner, 1985; Krose & Julesz, 1989; Nakayama & Mackeben, 1989) have proposed that visual space is influenced by corners. Recent studies by Cole, Burton and Gellatly (2001) found that reaction times were faster for a stimulus located in the region of a corner of a figure. Cole et al (2001) believe that the role of corners is greater than that of straight edges, due to corners receiving a higher distribution of attentional resources relative to straight edges. The first part of this thesis considers the role figure-ground plays in the corner enhancement effect. Results demonstrate that the corner enhancement effect is only found when the probe is presented on the surface that owns the corner. Thus the corner enhancement effect is present for both concave and convex vertices. However, the effect disappears when the probe lay on the surface that does not own the corner. The second series of experiments made use of a shape with multiple concave or convex features as part of a change detection task, in which only a single feature could change. The results provided no evidence to suggest that convexities are special in visual short-term memory. Though coding of convexities as well as concavities provided a small advantage over an isolated contour. This finding is in accordance with the well documented effect of closure on shape processing (Elder & Zucker, 1993). It has been reported that deviations from symmetry were easier to detect when carried by convexities compared to deviations carried by concavities (Hulleman & Olivers, 2007). We extended this investigation to shapes that were repeated instead of reflected, to test whether there is a specific convexity advantage for bilateral symmetry. The results supported a convexity advantage for repetitions but not for reflections. Possible explanations for this are discussed. The final series of experiments involved a shape interference task; observers responded to circles or square in the context of irrelevant circles and squares. The findings suggest that interference between the shapes is much stronger when the contours that define the shapes belong to the same surface. In summary, we conclude that convexity and concavity are important aspects of shape analysis and representation, but there is no basic difference in how convexities and concavities are attended to, both in the corner enhancement effect, and in visual-short term memory. However, convexity plays a role in some perceptual tasks for example, when analyzing complex shapes observers may adopt strategies that focus on the convexities.
Vertical integration: a real options approach

ABSTRACT We develop a theoretical real options model and explore the trade-off between vertical integration and external procurement. In contrast to transaction cost theory, we show that higher volatility in the downstream market reduces the likelihood to switch to internal production. We also analyse the decision to acquire the supplier and provide novel predictions on the acquisition likelihood and premium contributing to studies relating to vertical M&As.
Fractional-Order Control of High Speed Train With Actuator Complete Failure

With considering the uncertainties and nonlinearities, the position/velocity tracking control of high-speed train (HST) with redundancy actuators is investigated in this paper. Unlike the existing methods that focus on the actuator partial failure (APF), the actuator complete failure (ACF) is considered. A fractional-order controller (FOC) without a switching process is developed to achieve stable position/velocity tracking control with considering the ACF. And the established controller cannot only tackle the ACF without any fault detection process, but also compensate for uncertainties and nonlinearities of the system, improve the system in tracking accuracy and suppress disturbances caused by internal and external factors. Besides, the influence of different fractional orders on the control performance is analyzed theoretically, providing a basis for the choice of orders. Lyapunov stability theory and fractional order theory are employed to verify the effectiveness of FOC, and simulation studies show the consistency with theoretical analysis. The influence of different fractional orders is also tested in simulation, and further compared with traditional PID controller. It can be concluded that although either PID or FOC are able to cope with the system nonlinearities and uncertainties as well as ACF, there is great significance in FOC research for the promotion of control precision and robustness as well as anti-jamming ability.
Application of the Transtheoretical Model to Identify Physical Activity-Related Psychological Variables in Disabled Adults

OBJECTIVES The current study aimed at identifying the theoretical relation of the transtheoretical model (TTM) to explain physical activity in Korean adults with physical disabilities.METHODS A total of 194 participants ( Age Mean = 48.65 years) were voluntarily recruited for this study. Dissemination sources for participant recruitment included: (a) a press release issued through the authors’ university; (b) recruitment flyers posted on various websites (e.g., Independent Living Centers, Rehabilitation Research and Training Centers, Veteran’s Administration Hospitals); and (c) announcements made through and in conjunction with the Rehabilitation Research and Training Center on Health and Wellness consortium members. Through these procedures, 194 adults (80.83%) completed the survey form; there were 113 males (58.3%) and 81 females (41.7%). The remaining 46 (19.17%) were excluded because they did not complete the survey form or return.RESULTS Results indicated that the TTM constructs assessed were significantly (P < 0.001) associated with the stages of change for physical activity. The largest portion of variance was derived from the behavioral processes of change (ƞ2 = .40), followed by self-efficacy (ƞ2 = .30), the pros for exercise (ƞ2 = .19), the cognitive processes of change and the cons for exercise (ƞ2 = .16, respectively). Moreover, four discriminant functions (i.e., composite scores of the predictors) were produced in the first DDF analysis. These accounted for 71.0% (Wilks’ Λ = .31, χ2 [56] = 368.04, P < .001), 20.9% (Wilks’ Λ = .66, χ2 [39] = 129.91, P < 0.001), 6.3% (Wilks’ Λ = .88, χ2 [24] = 39.39, P < 0.05), and 1.8% (Wilks’ Λ = .97, χ2 [11] = 9.04, P = .62), respectively, of the between-group (stage of change) variability.CONCLUSIONS The results provide further cross-sectional support for the internal validity of the transtheoretical model, as the processes of change, self-efficacy, and decisional balance were important variables of a stage of change for physical activity, Additionally, the study is in general agreement with existing evidence among nondisabled populations and, therefore, it supports the external validation of TTM to a unique and understudied population segment.
Production Efficiency, Nutrient Utilization and Intestinal Histology of Broilers Fed on Energy Diluted Diet Supplemented with Lipase and Bile Acids

This study was carried out to determine the efficacy of lipase and emulsifier + lipase in broilers reared on energy diluted diet. Five hundred and twenty birds were divided into 8 treatments groups with 5 replicates of 13 birds in each. Total 8 diets viz., PC (Positive control), NC1 (Negative control 1; 75 Kcal/kg reduced energy), NC1L (NC1 + lipase at 0.015%), NC1LB (NC1 + lipase at 0.015% + bile acids at 0.05%), NC2 (Negative control 2; 150 Kcal/kg reduced energy), NC2L (NC2 + lipase at 0.015%), NC2LB (NC2 + lipase at 0.015% + bile acids at 0.05%) and NC2 (2LB) (NC2 + 2x (lipase at 0.03% + bile acids at 0.1%)) were formulated. Weight gain, feed intake (FI), protien efficiency ratio (PER), energy efficiency ratio (EER), mortality percentage and food conversion ratio (FCR) were similar (P > 0.05) by addition of lipase and bile acids in energy diluted diets during starter phase in broiler chicks. However, birds of NC1L group had higher European production efficiency factor (EPEF) than other treatments. Weight gain, PER, EER and EPEF were higher (P < 0.05) in birds of NC1LB group and lower (P < 0.05) in birds of NC2 and NC2L group. However, FCR was better (P < 0.05) in birds of NC1LB and NC2 (2LB) group and birds of NC2 group had poor (P < 0.05) FCR. Villus height of ilium and villus surface area was higher (P < 0.05) in birds of NC1LB and lower (P < 0.05) villus height and less (P < 0.05) villus surface area were recorded in NC2 group. In conclusion addition of lipase and bile acids as emulsifier in combination form had improved production efficiency and increased villous surface area in broilers reared on 75 kcal reduced energy diet.
An Overall Research on Industry Ecological and Technical Solutions for 5G-V2X in Port Park Scenario

Aiming at improving the user’s driving safety and travel efficiency and satisfying their future needs of highly autonomous driving services and based on the features of 5G’s ultralow latency, ultrahigh reliability, and ultrawide broadband, this paper proposes an overall solution for 5G-V2X, including industry ecological solutions and technical solutions. The industry ecological solutions include the analysis of the Internet of Vehicles industry chain architecture, future business models, and innovative ecosystems. The technical solutions include the overall solution for V2X, the overall blueprint of the planning function for V2X, core technology scenarios, and key technical capabilities. These solutions can integrate users, vehicles, and roads completely and effectively, which helps the government to achieve effective monitoring and management of intersection of user-vehicle-road and realizes the 5G-based V2X pan-transportation and logistics ecology. The validity and feasibility of these solutions are verified by some applications in the port park.
Production of Fungal Quinones: Problems and Prospects

Fungal quinones can be used for a variety of applications, such as pharmaceuticals, food colorants, textile dyes, and battery electrolytes. However, when producing quinones by fungal cultivation, many considerations arise regarding the feasibility of a production system, such as the quinone yield, purity, ease of extraction, and the co-production of mycotoxins. In this work, we display the initial screening of filamentous fungi for quinone production and evaluate their potential for future optimization. We investigated toluquinone (TQ) potentially produced by Penicillium cf. griseofulvum, terreic acid (TA) produced by Aspergillus parvulus and A. christenseniae, and anthraquinone (AQ) monomers and dimers produced by Talaromyces islandicus. The strains grew on various agar and/or liquid media and were analyzed by ultra-high-performance liquid chromatography–diode array detection–quadrupole time-of-flight mass spectrometry (UHPLC-DAD-QTOF MS). In the case of AQs, feature-based molecular networking (FBMN) was used for the identification of AQ analogs. TQ was not observed in the production strains. TA constituted one of the major chromatogram peaks and was secreted into the growth medium by A. parvulus. The AQs constituted many major chromatogram peaks in the mycelium extracts and endocrocin and citreorosein were observed extracellularly in small amounts.
Acoustic Float Tracking with the Kalman Smoother

Acoustically-tracked subsurface floats provide insights into ocean complexity and were first deployed over 60 years ago. A standard tracking method uses a Least-Squares algorithm to estimate float trajectories based on acoustic ranging from moored sound sources. However, infrequent or imperfect data challenge such estimates, and Least-Squares algorithms are vulnerable to non-Gaussian errors. Acoustic tracking is currently the only feasible strategy for recovering float positions in the sea ice region, a focus of this study. Acoustic records recovered from under-ice floats frequently lack continuous sound source coverage. This is because environmental factors such as surface sound channels and rough sea ice attenuate acoustic signals, while operational considerations make polar sound sources expensive and difficult to deploy. Here we present a Kalman Smoother approach that, by including some estimates of float behavior, extends tracking to situations with more challenging data sets. The Kalman Smoother constructs dynamically constrained, error-minimized float tracks and variance ellipses using all possible position data. This algorithm outperforms the Least-Squares approach and a Kalman Filter in numerical experiments. The Kalman Smoother is applied to previously-tracked floats from the southeast Pacific (DIMES experiment), and the results are compared with existing trajectories constructed using the Least- Squares algorithm. The Kalman Smoother is also used to reconstruct the trajectories of a set of previously untracked, acoustically-enabled Argo floats in the Weddell Sea.
CO2 Emission Labels in India: Whistling in the Wind?

We studied the effect of an environmentally conscious nudge on the choice of car that our respondents make. Our primary data driven study was conducted after adequately reviewing the literature pertaining to the field of behavioral environmental economics. Our experiment shows that the nudge worked in most cases, except those which involve the question of prestige and status. We also found that in case if the preference for a car in particular segment is high with a small difference in carbon dioxide (CO2) emissions, then the respondents tend to choose the car of their liking. It is concluded that tools like nudges are in indeed helpful in reducing the emission levels from what we currently have.
FBXW7 affects autophagy through MCL1 in oral squamous cell carcinoma.

BACKGROUND Oral cancer is associated with high risk of morbidity and mortality. However, effective treatment for oral cancer is urgently required in clinics. In this study, we aimed to determine whether F-box/WD repeat-containing protein 7 (FBXW7), an essential tumor suppressor gene, can regulate autophagy and improve the prognosis in oral squamous cell carcinoma (OSCC). METHODS mRNA levels of FBXW7 and myeloid cell leukemia 1 (MCL-1) in OSCC tissues and adjacent normal tissues were measured by qRT-PCR. FBXW7 and MCL-1 were overexpressed in OSCC cell line using lentivirus containing FBXW7 and MCL-1, respectively. Protein expression was determined by Western blot. RESULTS The mRNA and protein levels of FBXW7 were decreased in patients with OSCC, whereas the mRNA and protein levels of MCL-1 were increased. Moreover, the mRNA coding for autophagy proteins was reduced in patients with OSCC. Additionally, it was found that overexpression of FBXW7 significantly reduced MCL-1 expression and upregulated autophagy-related proteins, including Beclin1, autophagy related 7, and microtubule-associated protein light chain 3. CONCLUSION Our results suggest that FBXW7 affects autophagy through MCL1 in OSCC.
Integrasi Six Sigma dan FMEA (Failure Mode And Effect Analysis) untuk Peningkatan Kualitas Produk Koran (Studi Kasus: PT. ABC Manufacturing – Sidoarjo, Jawa Timur – Indonesia)

PT. ABC is a subsidiary of the JawaPos Group, founded in 1996, and is one of the companies in East Java engaged in printing and packaging. The products produced include magazines, books and newspapers. Of all the products that the company has created, one of the biggest defects is found in newspaper products, which is 4% of the average newspaper product production of 806.59 copies and produces a moderate defect of 22,743 copies in 2019. In this research, the method applied is the Six Sigma method and Failure Mode and Effect Analysis (FMEA), by implementing and carrying out the stages in the Six Sigma method, namely DMAIC (Define, Measure, Analyze, and Control). From this research, the results obtained are that the company has several newspaper product defects of 181,943 copies consisting of several types of product defects, including damp paper, blurred colours, shaded printing, asymmetrical printing, and running printing. The company is currently at the 4.04 sigma level, so corrective actions need to be taken to achieve six sigma levels. By applying the Failure Mode and Effects Analysis (FMEA) method, it can be seen that the biggest and most frequent product defect is a blurred colour defect. So that the recommended alternative solution for repairs is to check the ink and replace the ink with standard ink or have a lower density, perform regular and systematic machine checks, and provide further guidance on newspaper printing production standards to all operators involved work.