Miracle-dz/UniFAR-FTUs huggingface dataset:
UHF RFID Tags Zoning Using Harmonic Signals and Machine Learning

This paper describes an effective method for improving the detection of UHF RFID (Ultra High Frequency Radio Frequency Identification) tags in a restricted area. The so-called zoning technique is a recurring problem in practical RFID applications: it consists in detecting within an environment with multiple tags that are exclusively present in the zone of interest. The proposed method is based on the concept of Nth harmonic, a new paradigm that involves utilizing the harmonic signals backscattered by tags. Such a method is coupled with a machine learning technique. Experimental results show the importance of harmonic features for better tags zoning. Using a four-layer CNN classifier, we can achieve 99% prediction accuracy by leaving a keep-out distance of 0.5 m between two zones, using the harmonic RSSI (Received Signal Strength Indicator) sum feature, and 94.7% by using the best feature at $f_{0}$ , which is the RSSI max, achieving around 5 times less prediction errors. Furthermore, combining the harmonic and fundamental features leverage the prediction accuracy to 99.8%.
EFFICACY OF LACTOSE-FREE FORMULA AS A 24-HOUR MANAGEMENT APPROACH FOR ACUTE DIARRHEA AMONG CHILDREN

Background: Diarrhea continues to be a prominent contributor to morbidity and mortality among young children under five years, especially in developing nations. Secondary lactose intolerance is a significant complication that can arise from acute diarrhea. However, it can be effectively managed with lactose-free formula. Objective: This study aimed to compare the rate of diarrhea resolution within a 24-hour period among children receiving lactose-free formula and those receiving lactose-containing formula. Methods: This retrospective cohort study took place at Naresuan University Hospital and included 153 children aged between one month and five years admitted with acute diarrhea. Participants with bloody mucous diarrhea suspected to be bacterial in nature, positive stool culture, breastfeeding and chronic diarrhea (including cow’s milk protein allergy and inflammatory bowel disease) were excluded. We compared the effectiveness of lactose-free formula (n=48) and lactose-containing formula in improving clinical diarrhea within a 24-hour (n=105). Results: The study findings indicated the lactose-free formula group demonstrated a statistically significant increase in efficacy, with a 3.90 fold improvement in diarrhea within 24 hours compared with that of the group receiving lactose-containing formula. These results were obtained after the confounding factors were adjusted using multivariable regression analysis. The adjusted relative risk (RR) for a 24-hour improvement in diarrhea was 3.90 (95% CI: 1.91-7.95). However, this study encountered limitations regarding the sample size and accurate measurement of stool output. Conclusion: Lactose-free formula showed the potential for greater effectiveness in improving acute diarrhea within a 24-hour timeframe compared with lactose-containing formula.
Pathway-specific polygenic scores for Alzheimer’s disease are associated with changes in brain structure in younger and older adults

Abstract Genome-wide association studies have identified multiple Alzheimer’s disease risk loci with small effect sizes. Polygenic risk scores, which aggregate these variants, are associated with grey matter structural changes. However, genome-wide scores do not allow mechanistic interpretations. The present study explored associations between disease pathway-specific scores and grey matter structure in younger and older adults. Data from two separate population cohorts were used as follows: the Avon Longitudinal Study of Parents and Children, mean age 19.8, and UK Biobank, mean age 64.4 (combined n = 18 689). Alzheimer’s polygenic risk scores were computed using the largest genome-wide association study of clinically assessed Alzheimer’s to date. Relationships between subcortical volumes and cortical thickness, pathway-specific scores and genome-wide scores were examined. Increased pathway-specific scores were associated with reduced cortical thickness in both the younger and older cohorts. For example, the reverse cholesterol transport pathway score showed evidence of association with lower left middle temporal cortex thickness in the younger Avon participants (P = 0.034; beta = −0.013, CI −0.025, −0.001) and in the older UK Biobank participants (P = 0.019; beta = −0.003, CI −0.005, −4.56 × 10−4). Pathway scores were associated with smaller subcortical volumes, such as smaller hippocampal volume, in UK Biobank older adults. There was also evidence of positive association between subcortical volumes in Avon younger adults. For example, the tau protein-binding pathway score was negatively associated with left hippocampal volume in UK Biobank (P = 8.35 × 10−05; beta = −11.392, CI −17.066, −5.718) and positively associated with hippocampal volume in the Avon study (P = 0.040; beta = 51.952, CI 2.445, 101.460). The immune response score had a distinct pattern of association, being only associated with reduced thickness in the right posterior cingulate in older and younger adults (P = 0.011; beta = −0.003, CI −0.005, −0.001 in UK Biobank; P = 0.034; beta = −0.016, CI −0.031, −0.001 in the Avon study). The immune response score was associated with smaller subcortical volumes in the older adults, but not younger adults. The disease pathway scores showed greater evidence of association with imaging phenotypes than the genome-wide score. This suggests that pathway-specific polygenic methods may allow progress towards a mechanistic understanding of structural changes linked to polygenic risk in pre-clinical Alzheimer’s disease. Pathway-specific profiling could further define pathophysiology in individuals, moving towards precision medicine in Alzheimer’s disease.
β1-adrenergic receptor polymorphisms: a possible genetic predictor of bisoprolol response in acute coronary syndrome

Aim: To investigate the association between beta1-adrenergic receptor (ADRB1) polymorphisms and response to bisoprolol treatment in beta-blocker naive patients with acute coronary syndrome (ACS). Patients & methods: Seventy-seven patients received bisoprolol for four weeks. Blood pressure and heart rate were measured at baseline and during treatment. TaqMan allelic discrimination method was utilized for ADRB1 Ser49Gly and Arg389Gly genotyping. Results: Arg389Arg carriers showed greater reductions in systolic and diastolic blood pressure (-8.5% ± 7.8% vs -0.76% ± 8.7%, p = 0.000218), and (-9.5% ± 9.7% vs -0.80% ± 11.5%, p = 0.000149), respectively, compared with Gly389 carriers. No statistical difference was found for study's outcomes based on codon 49. Conclusion: Arg389Gly polymorphism is a promising bisoprolol response predictor in ACS patients.
Multistate Chipless RFID Tags for Robust Vibration Sensing

This article introduces multistate (M-S) chipless radio-frequency identification (RFID) tags that can be utilized to enhance the vibration sensing range and reading robustness in real environments. The proposed M-S chipless tag consists of a resonant scatterer trapped between two different dielectric layers, which causes the near-field boundary of the scatterer to be modulated during vibration and results in the appearance of multiple modulation states. The motion-induced near-field modulation provided by the M-S chipless tag is much more effective than the natural Doppler modulation caused by vibration, which significantly increases the modulated portion of the backscattered power, and consequently, enlarges the sensing range. The backscattering from the vibrating M-S chipless tag is studied using presented mechanical and electromagnetic models that are verified by simulations. The designed M-S chipless tag is implemented, and the concept is experimentally proven. The differential radar cross section (RCS) of the vibrating M-S chipless tag is 45 times greater than that of a vibrating classical chipless tag, which translates into an increase of factor 2.5 in the read range. The M-S chipless RFID tag is utilized to successfully detect a submillimeter vibration through a wall in an indoor environment at low microwave frequencies, while the vibrating tag is located at a 2.5-m distance.
Automated Staging and Grading for Retinopathy of Prematurity on Indian Database

Retinopathy of prematurity (ROP) is a disorder of the retina in neonates. If ROP is not treated at early stage, neonates’ vision is affected, leading to blindness. It is necessary to diagnose and treat ROP at earliest. Several ROP assessment techniques based on Image analysis have been introduced in recent years. These studies identify only normal, abnormal and plus disease. This research article explores the identification of distinct ROP stages along with normal and abnormal detection. Detecting the stages will help to expedite the treatment and prevent vision loss. The proposed framework consists of feature extraction using Scale Invariant Feature Transform (SIFT) and Pyramid Histogram of Words (PHOW) techniques. Three efficient supervised machine learning algorithms, namely random forest (RF), support vector machine (SVM) and extreme boosting gradient (XGBoost), are used to classify different stages of ROP. A data set captured by RetCam 3 is used to evaluate the model. Based on rigorous evaluation, the accuracy of different ROP stages is 93.68%, 83.33%, 85.71%, 55.55% and 100% for normal, stage 1, 2, 3 and 4, respectively.
Validation Test Report for the Improved Synthetic Ocean Profile (ISOP) System, Part I: Synthetic Profile Methods and Algorithm

Abstract : A new method is developed to utilize the relatively abundant satellite observations of sea surface temperature (SST) and sea surface height (SSH) and estimates of mixed layer depth (MLD) to create synthetic profiles of temperature and salinity for assimilation in the Navy's Global Ocean Forecasting System (GOFS). The traditional methods for creating synthetics have limitations particularly with regard to accuracy of the vertical ocean gradients. To address this issue, the Improved Synthetic Ocean Profile (ISOP) system has been developed to more correctly represent the ocean's vertical gradients using a three-layer approach accounting for the ocean's (1) surface mixed layer, (2) vertical gradients below the mixed layer through the thermocline, and (3) relatively quiescent depths. The present document covers the details of the background historical in situ observation database, the three-layer approach, the algorithms for each layer, and the global ISOP stand-alone synthetic validation.
Connectivity Conservation: Maintaining and restoring connectivity in landscapes fragmented by roads

INTRODUCTION Transportation networks and systems are vital to today's economy and society (Button and Hensher 2001). Not only do roads provide for safe and efficient movement of goods and people across cities and continents, throughout the world they have become a permanent part of our physical, cultural, and social environment (Robinson 1971; Lay 1992). Roads and their networks are one of the most prominent human-made features on the landscape today (Sanderson et al . 2002). Compared to polygonal blocks of built areas, road systems are linear and etched into the landscape to form a woven network of arteries that maintain the pulse of societies. However, as road networks extend across the landscape and their weave intensifies, natural areas become increasingly fragmented and impoverished biologically (Forman et al . 2003). Although less studied compared to other agents of fragmentation, roads cause changes to wildlife habitat that are more extreme and permanent than other anthropogenic sources of fragmentation (Forman and Alexander 1998; Spellerberg 2002). Road networks and systems not only cause conspicuous changes to physical landscapes, but also alter the patterns of wildlife and the general function of ecosystems within these landscapes (Swanson et al . 1988; Transportation Research Board 1997; Olander et al . 1998). Busy roads can be barriers or filters to animal movement (Hels and Buchwald 2001; Rondinini and Doncaster 2002; Chruszcz et al . 2003) and in some cases the leading cause of animal mortality (Maehr et al . 1991; Jones 2000; Kaczensky et al . 2003).
Keanekaragaman Makro-invertebrata di Pantai Sepanjang, Gunungkidul, di. YOGYAKARTA

Macroinvertebrates is one of bioindicator for aquatic ecosystem. By assessing indicator species, diversity, functional groups of macroinvertebrates community, it is possible to determine water quality. Purpose of this research was to inventory and study the macroinvertebrates species diversity in Sepanjang Beach, Gunungkidul, Yogyakarta. This research was conducted on Wednesday, November 25 th 2014 at Sepanjang Beach, Gunungkidul, Yogyakarta. Sampling points was determined by line transect method. At each transect, sampling with 1x1 m 2 plots was done. The data obtained in this study was the result of macro-invertebrates species inventory in each sampling point and the number of individuals of each species. Data analysis was performed by calculating the Shannon-Weiner diversity index (H’). Result of this research showed that there were 63 macroinvertebrates species with 1033 number of individuals found in Sepanjang beach. Result of calculation of Shannon-Weiner diversity index (H’) showed the diversity index of macro-invertebrates in Sepanjang beach was 1.24. The diversity index showed that the diversity index of macro-invertebrates in Sepanjang beach categorized by medium diversity.
Atomistic simulation of brittle-to-ductile transition in silicon carbide embedded with nano-sized helium bubbles

The tensile response of cubic silicon carbide (SiC) bulk containing cavities (voids and He bubbles) has been investigated using molecular dynamic simulations. The formation of cavities in SiC leads to a significant degradation in the mechanical properties of SiC with more influence on material fracture than initial elastic deformation. The brittle-to-ductile transition occurs in cavity-embedded SiC as the pressure in He bubbles increases. This is associated with the deformation mechanism that bond breaking at a low He bubble pressure transfers to extensive dislocation activities at a higher He bubble pressure. The cavities can effectively concentrate stress around them in the direction perpendicular to the tension, which leads to preferred cracking in the region with a higher tensile stress. The failure mechanism as revealed by this study improves understanding of property degradation in SiC that may be useful for applications of SiC in advanced nuclear energy systems.
Regulation of the renin-angiotensin-aldosterone system by cyclic nucleotides and phosphodiesterases

The renin-angiotensin-aldosterone system (RAAS) is one of the key players in the regulation of blood volume and blood pressure. Dysfunction of this system is connected with cardiovascular and renal diseases. Regulation of RAAS is under the control of multiple intracellular mechanisms. Cyclic nucleotides and phosphodiesterases are the major regulators of this system since they control expression and activity of renin and aldosterone. In this review, we summarize known mechanisms by which cyclic nucleotides and phosphodiesterases regulate renin gene expression, secretion of renin granules from juxtaglomerular cells and aldosterone production from zona glomerulosa cells of adrenal gland. We also discuss several open questions which deserve future attention.
Targeting FAK/PYK2 with SJP1602 for Anti-Tumor Activity in Triple-Negative Breast Cancer

Triple-negative breast cancer (TNBC) presents significant challenges due to its aggressive nature and limited treatment options. Focal adhesion kinase (FAK) has emerged as a critical factor promoting tumor growth and metastasis in TNBC. Despite encouraging results from preclinical and early clinical trials with various FAK inhibitors, none have yet achieved clinical success in TNBC treatment. This study investigates the therapeutic potential of a novel dual inhibitor of FAK and PYK2, named SJP1602, for TNBC. In vitro experiments demonstrate that SJP1602 effectively inhibits FAK and PYK2 activities, showing potent effects on both kinases. SJP1602 shows concentration-dependent inhibition of cell growth, migration, invasion, and 3D spheroid formation in TNBC cell lines, surpassing the efficacy of other FAK inhibitors. Pharmacokinetic studies in rats indicate favorable bioavailability and sustained plasma concentrations of SJP1602, supporting its potential as a therapeutic agent. Furthermore, in TNBC xenograft models, SJP1602 exhibits significant dose-dependent inhibition of tumor growth. These promising results emphasize the potential of SJP1602 as a potent dual inhibitor of FAK and PYK2, deserving further investigation in clinical trials for TNBC treatment.
Same (sea) bed different dreams: Biological community structure of the Haima seep reveals distinct biogeographic affinities

Deep-sea chemosynthetic communities, including hydrothermal vents and cold seeps, harbour hundreds of endemic species currently threatened by deep-sea mining and hydrocarbon extraction. The South China Sea (SCS), a semi-enclosed marginal sea with two well-investigated active seeps (Haima in the west and Site F in the east), provides an opportunity to understand the biogeography of chemosynthetic ecosystems. Here, we conducted extensive field surveys using Remotely Operated Vehicles (ROVs) and collected specimens for morphological observations, molecular barcoding, phylogenetic analysis, and stable isotope analysis. Cluster analyses were applied to reveal the community structure of vents and seeps in the Western Pacific and Northern Indian Ocean. A total of 65 species covering seven phyla and 14 classes have been identified from Haima, doubling the number of species reported previously. Among them, 35 species are currently known only from Haima. Stable isotope analysis shows a typical chemosynthesis-based biological community. Community structure analysis at the genus level clustered Haima with Site F, though the species compositions and dominance of two seeps are fairly distinct. Between the two active seeps in the SCS, the higher species richness and endemism at Haima are potentially due to multiple factors, including the unique environmental factors there and the geographic isolation in the northwestern corner of the SCS. Moreover, a similarity in community compositions at the genus level between seeps in the SCS and North Indian Ocean was revealed, potentially mediated by the Early Pliocene opening of the Indonesian islands and the strong westward Indonesia Throughflow. Given the ongoing gas hydrate exploration activities in the SCS, our results will contribute to establishing a global network of marine protected areas for chemosynthetic-based ecosystems. The rich and endemic biodiversity at Haima calls for policymakers to formulate regulations to conserve the unique biodiversity there.
Southeast Asia. The nature and culture of rattan: Reflections on vanishing life in the forests of Southeast Asia . By Stephen F. Siebert. Honolulu: University of Hawai'i Press, 2012. Pp. xii, 145. Tables, Photographs, Notes, Bibliography, Index.

sidering the diversity and complexity of Asia reflected in its historically fluid boundaries, they have ‘intentionally avoided ascribing too hard and fast a definition of what constitutes Asia as a region’ is contradicted by its blurb, which states that the book covers ‘the entire region’ of Asia, which is potentially misleading, since no chapter treats Central Asia, for one (p. 6). It would have been nice to include some coverage of language, spoken or written, a critically urgent issue of heritage. However, one can learn a tremendous amount from this book which, among other things, includes exhaustive bibliographies. With its innovative and cohesive scholarship, it makes for an indispensable volume for heritage studies and related fields such as social policy, religion, tourism, history, and urban planning.
London : the secret history of our streets : a social history through the houses and streets we live in

The Secret History of Our Streets explores one of the great forces shaping our lives: property. Why we live where we live, and how that choice informs the lives we lead. In a modern version of Charles Booth's 1886 Survey of London, this remarkable book tells the story of six London streets, representing the widest possible picture of the city both socially and geographically. Each has a fascinating story of its own. Together, their stories reveal the big underlying forces that have shaped Britain for the last 120 years: gentrification, migration, slum clearance, property speculation and the urban sprawl. The six streets and larger themes they address are Deptford High Street - the mania for re-development, slum clearances; Portland Road - gentrification and 'super-gentrification' (the rich being pushed out by the super-rich); Reverdy Road - the white working class, the Blitz and redevelopment; Caledonian Road - ownership and landlords, the prison; Arnold Circus - public housing; Camberwell Grove - the disappearance of rural idyll, the rise of the suburbs.
The complete reversal effect following angiotensin-converting enzyme inhibitors or angiotensin receptor blockers and beta-blockers after the primary diagnosis of dilated cardiomyopathy

Background: Whether combination administration of angiotensin-converting enzyme inhibitors (ACEIs), angiotensin receptor blockers (ARBs), and beta-blockers (BBs) has a “reversal” effect on cardiac structure and function for first-diagnosed idiopathic dilated cardiomyopathy (FSIDCM) patients with unclear etiologies and inducements is unknown. Materials and Methods: We studied the effect of the protocol on FSIDCM patients. The effect was investigated in 26 FSIDCM patients. The criteria of “complete reversal” included left ventricular end-diastolic diameter (LVEDD) ≤50 mm for females or ≤55 mm for males and left ventricular ejection fraction (LVEF) ≥45%; the criteria of “partial reversal” was the decreased rate of LVEDD (ΔLVEDD) >10% or the increase rate of LVEF (ΔLVEF) >10%; the criteria of “no reversal” included LVEDD >50 mm for females or >55 mm for males and ΔLVEDD <10%, and LVEF <45% and ΔLVEF <10%. Results: Within the follow-up period, nine patients showed “complete reversal,” eight “partial reversal,” and nine “no reversal. ” Improvements in echocardiogram parameters were the most significant in “complete reversal” patients (P < 0.001), followed by “partial reversal” and “no reversal” patients (P < 0.05). The QRS (Q wave, R wave, S wave) duration and symptoms duration in “complete reversal” patients were the shortest, followed by “partial reversal” and “no reversal” patients. Conclusion: ACEIs or ARBs and BBs have a “complete reversal” effect on the left ventricular size and function of some FSIDCM patients. Patients with a narrow QRS and short symptom duration may have a good response.