Miracle-dz/UniFAR-FTUs huggingface dataset:
Investigating the degradation behaviour and characteristic changes of phase pure hydroxyapatite (HAp) microsphere scaffolds under static and dynamic conditions

ABSTRACT Hydroxyapatite (HAp) has been widely researched on due to its chemical similarity to native bone. HAp microspheres can encourage good cellular attachment due to their high surface area to volume ratio, facilitating further proliferation and differentiation of cells at later stages. To ensure the reliability and effectiveness of HAp microspheres in physiological conditions, we investigated their behaviour and key characteristic changes in both static and dynamic conditions. We found both environments exhibiting similar results but noticeably the microspheres in the dynamic environment resulted in faster rate of degradation. The degradation mechanism follows that of a surface degradation process. Microspheres underwent reduction in size and weight loss upon release of Ca2+ ions into Dulbecco’s Phosphate Buffered Saline medium (DPBS). Apatite reprecipitation was visible in the form of granular deposits in both environments from day 1 and continued throughout 21 days which altered the size of the microspheres but not its shape.
CFAVC scheme for high frequency series resonant inverter-fed domestic induction heating system

This article presents the investigations on the constant frequency asymmetric voltage cancellation control in the AC–AC resonant converter-fed domestic induction heating system. Conventional fixed frequency control techniques used in the high frequency converters lead to non-zero voltage switching operation and reduced output power. The proposed control technique produces higher output power than the conventional fixed-frequency control strategies. In this control technique, zero-voltage-switching operation is maintained during different duty cycle operation for reduction in the switching losses. Complete analysis of the induction heating power supply system with asymmetric voltage cancellation control is discussed in this article. Simulation and experimental study on constant frequency asymmetric voltage cancellation (CFAVC)-controlled full bridge series resonant inverter is performed. Time domain simulation results for the open and closed loop of the system are obtained using MATLAB simulation tool. The simulation results prove the control of voltage and power in a wide range. PID controller-based closed loop control system achieves the voltage regulation of the proposed system for the step change in load. Hardware implementation of the system under CFAVC control is done using the embedded controller. The simulation and experimental results validate the performance of the CFAVC control technique for series resonant-based induction cooking system.
Cell- and non-cell-autonomous ARF3 coordinates meristem proliferation and organ patterning in Arabidopsis

In cell–cell communication, non-cell-autonomous transcription factors play vital roles in controlling plant stem cell fate. We previously reported that AUXIN RESPONSE FACTOR 3 (ARF3), a member of the ARF family with critical roles in floral meristem maintenance and determinacy, has a distinct accumulation pattern that differs from the expression domain of its encoding gene in the shoot apical meristem (SAM). However, the biological meaning of this difference is obscure. Here, we demonstrate that ARF3 expression is mainly activated at the periphery of the SAM by auxin, where ARF3 cell-autonomously regulates the expression of meristem–organ boundary-specific genes, such as CUP-SHAPED COTYLEDON1-3 (CUC1-3), BLADE ON PETIOLE1-2 (BOP1-2) and TARGETS UNDER ETTIN CONTROL3 (TEC3) to determine organ patterning. We also show that ARF3 is translocated into the organizing center, where it represses cytokinin activity and WUSCHEL expression to regulate meristem activity non-cell-autonomously. Therefore, ARF3 acts as a molecular link that mediates the interaction of auxin and cytokinin signaling in the SAM while coordinating the balance between meristem maintenance and organogenesis. Our findings reveal an ARF3-mediated coordination mechanism through cell–cell communication in dynamic SAM maintenance.
The Effects of Mobile Payment Dimensions toward Continuance Intention in Surabaya

—The 4.0 industrial revolution allows people to make payments using mobile devices which is called mobile payment. Mobile payment users in Indonesia have enlarged a significant improvement in the last few years. However, the use of mobile payment in Indonesia has not dominated yet. Most of the payments that they use are ATM Transfers, debit cards, and internet banking. These indicate the lack of continuance intention in using a mobile payment. The aim of this study is to examine the effects of mobile payments dimension (mobility, customization, security, reputation), service quality toward continuance intention through trust, and also the effects of trust toward continuance intention through perceived risk. The data used in this study are obtained through a research questionnaire. Respondents in this study were 170 Go-Pay and OVO users domiciled in Surabaya who made transactions with Go-Pay and OVO at least twice in the last few months. The sampling method of this study was non-probability sampling. This study uses a quantitative approach with the Structural Equation Modeling (SEM) method for statistical test. SEM analysis was carried out using the Analysis of Moment Structures (AMOS). The results of this study indicate that mobility and security have a significant positive effect on trust. On the other hand customization, reputation, and service quality do not affect trust. Trust has a significant positive effect on continuance intention and perceived risk. Meanwhile, the perceived risk made a significant negative effect on continuance intention.
The complete mitochondrial genome and molecular phylogeny of the flathead Platycephalus cultellatus Richardson, 1846 from Vietnam (Teleostei; Scorpaeniformes)

The family Platycephalidae is a taxonomic group of economically important demersal flathead fishes that predominantly occupy tropical or temperate estuaries and coastal environments of the Indo-Pacific oceans and the Mediterranean Sea. In this study, we for the first time analyzed the complete mitochondrial genome (mitogenome) of the flathead Platycephalus cultellatus Richardson, 1846 from Vietnam by Next Generation Sequencing method. Its mitogenome was 16,641 bp in total length, comprising 13 protein-coding genes (PCGs), two ribosomal RNA genes, and 22 transfer RNA genes. The gene composition and order of the mitogenome were identical to those of typical vertebrates. The phylogenetic trees were reconstructed based on the concatenated nucleotide sequence matrix of 13 PCGs and the partial sequence of a DNA barcoding marker, cox1 in order to determine its molecular phylogenetic position among the order Scorpaeniformes. The phylogenetic result revealed that P. cultellatus formed a monophyletic group with species belonging to the same family and consistently clustered with one nominal species, P. indicus , and two Platycephalus sp. specimens. Besides, the cox1 tree confirmed the taxonomic validity of our specimen by forming a monophyletic clade with its conspecific specimens. The mitogenome of P. cultellatus analyzed in this study will contribute valuable information for further study on taxonomy and phylogeny of flatheads.
Conceptual Design of a Connected Pipe Test Facility for Ramjet Applications

Connected pipe testing can be used in the development of the combustor of a ramjet engine. Typical pressures, temperatures, Mach numbers, and air mass flow rates of actual ramjet operations can be simulated by this method. Real time trajectory conditions and transition from rocket motor (booster) to ramjet operation can also be tested. The most important advantage of connected pipe testing over other methods is its low operation cost and simplicity. In this study, a connected pipe test facility has been designed to study ramjet combustors. Three main systems are analyzed; air storage system, air heater system, and test stand. The effects of different flame stabilization mechanisms are investigated for the vitiator and the ramjet combustor. The designed air storage system can provide test duration of 200 seconds with air mass flow rate of 1.5 to 8.0 kg/s and combustor pressure in the range of 2 to 8 bars. A methane/air vitiator with oxygen replenishment is designed to provide air inlet temperatures from 400 to 1000 K.
Management for engineers in multi-national society.

Zakum Development Company (ZADCO) is an operating company established in 1977 in Abu Dhabi to develop Upper Thamama Formations of Zakum field, which is the fifth largest oil field in the world. Like other operating companies such as Abu Dhabi Company for Onshore Operations (ADCO) and Abu Dhabi Marine Operating Company (ADMA-OPCO), ZADCO has employees whose nationalities are more than thirty countries. This situation can be described as multi-national society, implying different languages, religions, cultures, ways of thinking and so on.After the merger of ZADCO and Umm A1 Dalkh Development Company in 1988, tens of Japanese staff seconded by Japan Oil Development Company (JODCO) have been contributing to ZADCO operations under this environment, which is very different to the one in Japan. Job description combined with grading system adopted in the Operating Companies in Abu Dhabi is also unfamiliar to many of these Japanese secondees. Due to these differences, Japanese secondees normally encounter a lot of difficulties in showing their capabilities, particularly for the first three to six months of their new assignments. However, once they get accustomed to the differences, many secondees fulfill their duties to improve company's efficiencies and performances, cooperating with their foreign colleagues and friends.
Temozolomide-Acquired Resistance Is Associated with Modulation of the Integrin Repertoire in Glioblastoma, Impact of α5β1 Integrin

Simple Summary Glioblastomas are the deadliest brain tumours. The standard of care associates surgery, radio- and chemotherapy with Temozolomide as the reference drug. Despite this treatment, most of the tumours recur. The characterization of resistance mechanisms is of paramount importance to enable the proposal of more effective therapies. In this work we aimed to evaluate the molecular changes occurring during and after Temozolomide treatment in a glioma cell line. A high plasticity in the integrin repertoire exists in these cells. As an example, variations of the α5β1 integrin expression were observed with a reduction during the treatment and re-expression after removal of the drug. The association of integrin antagonists with p53 reactivators appears to be efficient in recurrent tumours. Specific integrins may thus be particularly targetable at different time points of glioblastoma treatment and combination therapies evaluated according to their time-dependent expression. Abstract Despite extensive treatment, glioblastoma inevitably recurs, leading to an overall survival of around 16 months. Understanding why and how tumours resist to radio/chemotherapies is crucial to overcome this unmet oncological challenge. Primary and acquired resistance to Temozolomide (TMZ), the standard-of-care chemotherapeutic drug, have been the subjects of several studies. This work aimed to evaluate molecular and phenotypic changes occurring during and after TMZ treatment in a glioblastoma cell model, the U87MG. These initially TMZ-sensitive cells acquire long-lasting resistance even after removal of the drug. Transcriptomic analysis revealed that profound changes occurred between parental and resistant cells, particularly at the level of the integrin repertoire. Focusing on α5β1 integrin, which we proposed earlier as a glioblastoma therapeutic target, we demonstrated that its expression was decreased in the presence of TMZ but restored after removal of the drug. In this glioblastoma model of recurrence, α5β1 integrin plays an important role in the proliferation and migration of tumoral cells. We also demonstrated that reactivating p53 by MDM2 inhibitors concomitantly with the inhibition of this integrin in recurrent cells may overcome the TMZ resistance. Our results may explain some integrin-based targeted therapy failure as integrin expressions are highly switchable during the time of treatment. We also propose an alternative way to alter the viability of recurrent glioblastoma cells expressing a high level of α5β1 integrin.
SYNTHESIS OF GOLD NANOPARTICLES DECORATING GRAPHENE FOAM AND ITS APPLICATION TO ELECTROCHEMICAL AND SERS -BASED SENSOR

In this study, Gold nanoparticles (GNPs) were synthesized by electrodeposition technique on the surface of Graphene Foam (GF) by fast scan voltammetry with using Gold (III) chloride trihydrate as the solvent. Then, the synthesized of gold nanoparticles were used in electrochemical sensor and surface-enhanced Raman Spectroscopy (SERS) for detection of sample analyt (200 μl hydrogen peroxide) and (1μMmethylene blue) respectively. The results demonstrate that gold nanoparticles enhanced amplification ofelectrochemical and SERSeffect on graphene foam (GF). The sensitivity of the sensor and size of gold nanoparticles could be controlled by the deposition of time, concentration of reducing agent and applied potential. Therefore, GNPs and GNPs/GF are highly promisingmaterial for electrochemical and SERS substrate for detection of chemical substance in low concentration
Impact of Face Masks and Viewers’ Anxiety on Ratings of First Impressions from Faces

Face mask is now a common feature in our social environment. Although face covering reduces our ability to recognize other's face identity and facial expressions, little is known about its impact on the formation of first impressions from faces. In two online experiments, we presented unfamiliar faces displaying neutral expressions with and without face masks, and participants rated the perceived approachableness, trustworthiness, attractiveness, and dominance from each face on a 9-point scale. Their anxiety levels were measured by the State-Trait Anxiety Inventory and Social Interaction Anxiety Scale. In comparison with mask-off condition, wearing face masks (mask-on) significantly increased the perceived approachableness and trustworthiness ratings, but showed little impact on increasing attractiveness or decreasing dominance ratings. Furthermore, both trait and state anxiety scores were negatively correlated with approachableness and trustworthiness ratings in both mask-off and mask-on conditions. Social anxiety scores, on the other hand, were negatively correlated with approachableness but not with trustworthiness ratings. It seems that the presence of a face mask can alter our first impressions of strangers. Although the ratings for approachableness, trustworthiness, attractiveness, and dominance were positively correlated, they appeared to be distinct constructs that were differentially influenced by face coverings and participants’ anxiety types and levels.
Un espace de conception pour explorer la continuité des affordances motivationnelles dans un contexte scolaire hybride.: A design space for the exploration of motivational affordances continuity in hybrid learning environments

Hybrid environments in education can alter the notion of space and time for learners who may have difficulty making links and perceiving complementarity between the different times, places, spaces and tools they use. This discontinuity can have negative impacts on learners' motivation. Classical approaches to support motivation, such as gamification, are usually designed for a given context (or situation) and are not well adapted to support students with breaks in space and time. Some works inspired by tangible interfaces and data physicalization are emerging and try to fill in the gap between these different spaces. However, their design still raises lots of questions. In this article we propose to structure the reflection around the design of such objects by proposing a design space. Based on an exploratory study and the literature review, we propose to consider three dimensions of motivation (spatial, temporal and social) and seven properties to consider in order to design objects that ensure the continuity of motivation. Finally, we detail the next steps of this work and research avenue to consider. L'hybridation des environnements scolaires complexifie la notion d'espace-temps pour les apprenants qui peuvent rencontrer des difficultés à faire le lien et à percevoir une complémentarité entre les différents temps, lieux, espaces et outils de travail qu'ils utilisent. Cette discontinuité liée à l'hybridation peut affecter la motivation des apprenants. Les approches classiques pour soutenir la motivation, comme la ludification, ne sont souvent pensées que pour un contexte donné et non pour accompagner l’élève dans les ruptures d'espace-temps. Des travaux s'inspirant des interfaces tangibles et de la physicalisation des données commencent à émerger pour faire le lien entre ces différents espaces. Cependant leur conception soulève encore beaucoup de questions. Dans cet article nous nous proposons de structurer la réflexion autour du design de tels objets en proposant un espace de conception. A partir d'une étude exploratoire et de la littérature, nous proposons de considérer trois dimensions de la motivation (spatiale, temporelle et sociale) et sept propriétés à considérer pour concevoir des objets permettant d'assurer la continuité de la motivation. Nous détaillons enfin les prochains travaux et pistes de recherche envisagées.
Post-Intensive Care Syndrome in Survivors from Critical Illness including COVID-19 Patients: A Narrative Review

Current achievements in medical science and technological advancements in intensive care medicine have allowed better support of critically ill patients in intensive care units (ICUs) and have increased survival probability. Post-intensive care syndrome (PICS) is a relatively new term introduced almost 10 years ago, defined as “new or worsening impairments in physical, cognitive, or mental health status arising after critical illness and persisting beyond acute care hospitalization”. A significant percentage of critically ill patients suffer from PICS for a prolonged period of time, with physical problems being the most common. The exact prevalence of PICS is unknown, and many risk factors have been described well. Coronavirus disease 2019 (COVID-19) survivors seem to be at especially high risk for developing PICS. The families of ICU survivors can also be affected as a response to the stress suffered during the critical illness of their kin. This separate entity is described as PICS family (PICS-F). A multidisciplinary approach is warranted for the treatment of PICS, involving healthcare professionals, clinicians, and scientists from different areas. Improving outcomes is both challenging and imperative for the critical care community. The review of the relevant literature and the study of the physical, cognitive, and mental sequelae could lead to the prevention and timely management of PICS and the subsequent improvement of the quality of life for ICU survivors.
Foreign Labor Migration Causes and Impacts in Nepal

This paper reflects the situation of foreign labour migration of Nepalese People. Globally, foreign labour migration is in increasing trends. In Nepalese context also foreign labour migration is being more important for employment mainly among unemployed people and youths who entered in labour force market. The number of foreign labour migrants and share of remittance in terms of GDP has increased. This article is based on secondary sources of information. The Global Commission on International Migration (GCIM) describes the driving forces in international migration in terms of “3Ds” (development, demography and democracy). In one side foreign labour migration has contributed to reduce poverty level and in other the income gap among migrants and non-migrants been increased. In addition, due to mail domination in foreign labour migration the role of women has been changed in households and society. It has contributed women empowerment mainly in male labour migrant’s households. Migration has occurred throughout history, and current trends certainly indicate that it will continue to increase in the future. The forces of globalization have created opportunities for greater integration of labour market globally.
High-order incremental sigma–delta for compressive sensing and its application to image sensors

ΣΔ ADCs show promising perspectives in the field of compressive sensing (CS). A major limitation related to the first-order ΣΔ is its high oversampling ratio (OSR) that is required for a specific bit resolution. An extension to the high-order incremental ΣΔ for the implementation of a dedicated image sensor is presented. By extending the concept of the ΣΔ CS ADC, optimal working points can be reached between the OSR and the compression ratio. Simulations of a particular fourth-order ADC combined with the authors column-based Bernoulli CS scheme show a severe relaxation on the ADC master clock.
Text Embedding Augmentation Based on Retraining With Pseudo-Labeled Adversarial Embedding

Pre-trained language models (LMs) have been shown to achieve outstanding performance in various natural language processing tasks; however, these models have a significantly large number of parameters to handle large-scale text corpora during the pre-training process, and thus, they entail the risk of overfitting when fine-tuning for small task-oriented datasets is conducted. In this paper, we propose a text embedding augmentation method to prevent such overfitting. The proposed method applies augmentation to a text embedding by generating an adversarial embedding, which is not identical to original input embedding but maintaining the characteristics of the original input embedding, using PGD-based adversarial training for input text data. A pseudo-label that is identical to the label of the input text is then assigned to adversarial embedding to conduct retraining by using adversarial embedding and pseudo-label as input embedding and label pair for a separate LM. Experimental results on several text classification benchmark datasets demonstrated that the proposed method effectively prevented overfitting, which commonly occurs when adjusting a large-scale pre-trained LM to a specific task.
Universiteto projekt ų vadybos brandos vertinimo aspektai

Stipr ÷janti konkurencija, globalizacijos procesai, uiniom is ir inovacijomis gr įstos ekonomikos pl÷tra, vartotoj ų poreiki ų reikom ÷s did ÷jimas ir produkto kokyb ÷s gerinimo b ūtinumas skatina tiek valstybines tiek vieo ąsias organizacijas, transformuotis io tradicinio valdymo organizacij ų į projektines organizacijas. Moksliniuose uurnaluose net teigiama, kad XXI a. projekt ų valdymas pakeis tradicin e funkcin e vadyb ą [13]. Organizacij ų virsmas projektin ÷mis organizacijomis kelia naujus reikalavimus valdymui ir reikalauja nauj ų esminių kompetencijų. Dauguma oiuolaikini ų organizacij ų pl÷tojamos projektais ‐ j ų veiklos strategijos įgyvendinamos vykdant projektin e veikl ą. Daunoje organizacijoje vienu metu įgyvendinama ne vienas, o keli ar net kelios deoimtys projekt ų. Tokiu atveju organizacijos turi geb ÷ti atrinkti ir valdyti