Miracle-dz/UniFAR-FTUs huggingface dataset:
AMPHIBIA: ANURA: HYLIDAE

• DEFINITION. Body size in this hylid frog is very large (maximum SVL 109 mm in males and 142 mm in females) and sexual dimorphism is extreme, with some mature females exceeding the size of mature males by 50% of SVL. The dorsum is strongly tuberculate and the venter is coarsely granular. Tubercles are present around the vent. Fingers are three-fourths webbed, and the toes are fully webbed. The foreand hindlimbs are fringed, and the digital disks are 1.2–1.5 times as wide as the toe. Dorsal color varies from shades of green to gray (at times a very dull greenish gray) and bears a diffuse pattern of dark gray to black markings. A rusty inverted T-shaped figure between the eyes and snout is often present. Hindlimbs are cross-barred with olive and pale green, usually most conspicuously on the crura (1 wide bar). The venter is white, and the chin, throat, and chest (in males) have scattered dark green spots or dots. Concealed surfaces are gray, purplish, or tan. The iris is bronze to gold. Juveniles are dark gray with a greenish cast. Noble (1923a) described the call (“ook-ook-ook”) and noted (1925, 1927) that tadpoles have small external gills, large adhesive mouths, no dorsal fins, slender body-forms, and thick tails.
The Fc g RIa (CD64) Ligand Binding Chain Triggers Major Histocompatibility Complex Class II Antigen Presentation Independently of Its Associated FcR g -Chain

Within multi-subunit Ig receptors, the FcR g -chain immunoreceptor tyrosine-based activation motif (ITAM) plays a crucial role in enabling antigen presentation. This process involves antigen-capture and targeting to specific degrada- tion and major histocompatibility complex (MHC) class II loading compartments. Antigenic epitopes are then pre- sented by MHC class II molecules to specific T cells. The high-affinity receptor for IgG, hFc g RIa, is exclusively expressed on myeloid lineage cells and depends on the FcR g -chain for surface expression, efficient ligand binding, and most phagocytic effector functions. However, we show in this report, using the IIA1.6 cell model, that hFc g RIa can potentiate MHC class II antigen presentation, independently of a functional FcR g -chain ITAM. Immunoelectron micro-scopic analyses documented hFc g RIa a -chain/rabbit IgG-Ovalbumin complexes to be internalized and to migrate via sorting endosomes to MHC class II-containing late endosomes. Radical deletion of the hFc g RIa a -chain cytoplasmic tail did not affect internalization of rabbit IgG-Ovalbumin complexes. Importantly, however, this resulted in diversion of receptor-ligand complexes to the recycling pathway and decreased antigen presentation. These results show the hFc g RIa cytoplasmic tail to contain autonomous targeting information for intracellular trafficking of receptor-antigen complexes, although deficient in canonical tyrosine- or dileu-cine-targeting motifs. This is the first documentation of autonomous targeting by a member of the multichain FcR family that may critically impact the immunoregulatory role proposed for hFc g RIa (CD64).
Surfactant therapy and SP-D in managing COVID-19 ARDS – therapeutic role possible ?

: Every liquid-solid interface is subject to an interfacial tension also known as surface tension. Agents that reduce this interfacial tension are termed as surfactants. Surfactants in the lungs are associated with two major functions namely reduction of surface tension to prevent the collapse of alveoli post expiration and modulating the lung environment to prevent pathogenic harm. Surfactants help by governing cellular functions since it orchestrates the communication, modification, and trafficking of secretory and membrane proteins which trigger immune pathways. Acute Respiratory Distress Syndrome (ARDS) which is very common in premature babies has been treated extensively in with pulmonary surfactants in the past with a 50% rise in positive outcomes. Although ARDS in COVID-19 is novel, SARS-CoV and SARS-CoV2 both use ACE2 (Angiotensin converting Enzyme) as their host cell receptor to establish infection. ACE2 is expressed in almost all cells in the body. ACE2 is highly expressed on surfactant producing type 2 alveolar cells in the lungs, and on ciliated and goblet cells in the airways; these cells likely provide a portal of entry for the virus in humans. There is currently no pharmaceutical agent to help the critically ill patients except for Positive end expiratory pressure (PEEP) and Non-invasive ventilation (NIV), we should not overlook that the role of surfactant might benefit these kinds of patients by helping improve oxygenation. This review will help understand how an old weapon of surfactant could benefit COVID battle armamentarium and help save lives. After a brief discussion on whether or not surfactant proteins, especially SP-D, should be included; this review also tries to explore the immune-modulation of surfactant protein (SP-D) and connection in COVID disease and its outcomes in obese, diabetic, and co-morbid people. This review emphasizes the dwindling surfactant balance as a putative therapeutic target for the treatment of COVID complications, and therefore, the urgent need for the development of better and safe agents for the severe respiratory syndrome of corona viral disease.
Prevalence of Iodine-induced Hyperthyroidism after Administration of Iodinated Contrast during Radiographic Procedures: A Systematic Review and Meta-analysis of the Literature

Background: Iodine-induced hyperthyroidism (IIH) was a common issue in the early twentieth century after introduction of iodine supplementation in dietary salt. Currently, IIH is mostly encountered in Western countries as a consequence of radiographic procedures involving the administration of iodinated contrast media (ICM). However, little is known about the magnitude and clinical relevance of this issue. To assess the incidence of hyperthyroidism after ICM exposure, we performed a systematic review and meta-analysis of the literature. Methods: MEDLINE,
RHEUMATOID ARTHRITIS AND NANOTHERAPEUTICS

are key members the MPS ABSTRACT Rheumatoid arthritis (RA) is an autoimmune, symmetrical polyarticular disease that affects primarily the diarthrodial joints, which are characterized by chronic inflammation of the synovial joints. Inflammation is the net result of a cascade of highly regulated events propagated upon stimulation, and is the major process through which the body repairs tissue damage and defends itself against foreign materials. Acute inflammation is typically caused by an external chemical, mechanical, or pathogenic influence; while chronic inflammation requires no external stimulus and can cause a range of painful and debilitating symptoms. Histological changes occur with abnormal cell distribution in targeted tissues and indicate localized population of macrophages and lymphocytes, then fibrosis and necrosis. Nanoparticles sized between 1 and 100 nm are already in use including cosmetics, food industry, medicine, electronics, and others. Exposure to nanomaterials induces cell dysfunctions at various levels, such as cell death by oxidative stress, DNA damage, and protein damage. Cell damage produces free radicals including reactive oxygen species (ROSs) and reactive nitrogen species (RNSs). It was also reported that generation of various inflammatory mediators, depends on type of nanoparticles. Present review highlights on the role of various nanoparticles on inflammation including, silica, iron oxide, cerium oxide, yttrium oxide, zinc oxide, silver, nickel oxide and Synthetic hydroxyapatite nanoparticles.
Physico – Morphological Characteristics and Fertilizing Ability Studies on Semen of Holstein Friesian Bull

Semen samples from apparently healthy and sexually matured six Holstein Friesian bull were collected using artificial vagina as per the standard practice. The ejaculates were evaluated and characterized for various physico – morphological characteristics as well as in – vitro fertility using hypo – osmotic swelling tests. Seminal attributes i.e. the average semen volume, colour, consistency, pH, average sperm concentration, average initial motility, average live sperm count, abnormal sperm count, methylene blue reduction test and sperm membrane integrity of Holstein Friesian were 7.67±1.12 ml, Creamy white, Medium – thick, 6.55±0.06, 1119.00 ±46.74 millions/ml, Good (90%), 81.50±2.13%, 10.67±0.49%, 4.38±0.20 minutes and 87.67±2.08% respectively. It can be concluded that semen of Holstein Friesian bull was of good quality. Hence, it may be utilized for freezing and further use in propagation and development of the respective breeds.
Real-time Joint Based Human Activity Recognition using RGB-Depth Camera

—Human activity recognition (HAR) has gained an effective role for computer vision in the problem of video surveillance systems and medical purposes. This study represents an approach for a biometric system that can recognize human activities in 3D space. Related approaches have shown that monitoring of various physiological signals can provide distinctive information to recognize human activities. The proposed method conducts a machine learning to determine a pattern on numerous activities using angles between joints in 3D space. Basically, activity related joint angles are obtained using Microsoft Kinect v2 sensor. Since HAR is operated in a time domain, joints’ angle information is stored in every 20 frames. Stored information consist the feature set for human activity recognition. Support vector machine (SVM) is used for both train and test. Among six different human activities, obtained average accuracy is 99,999482 %.
ON ASYMPTOTIC FORMULA FOR ELECTRIC RESISTANCE OF CONDUCTOR WITH SMALL CONTACTS

We construct and justify rigorously the complete asymptotic expansion for the electric resistance of a three-dimensional resistance connected by two small contacts of arbitrary shape. We obtain explicit formulae for the ﬁrst two terms in the asymptotics gen-eralizing the classical Holm formula of one-term asymptotics for two small round contacts of same radius.
An Approach to Detect Vulnerabilities in Web-based Applications

: The web applications are suppressed of distinctive programming models and interacting technologies that harvests ever-changing web application security. These interactions between distinctive technologies can cause new challenges for the security researchers. In present era, billions of individuals connect to numerous web-based applications for searching information; interact with other individuals for business purposes etc. Some of these crucial web-based services are targeted by the suspicious users that intend to exploit the vulnerabilities, which not only disrupt the services but also the critical information of particular organizations. Thus, securing these web applications against these vulnerabilities is very crucial and challenging. The study of these severe vulnerabilities, detection of attacks and providing solution for these vulnerabilities are the essential part in the internet world. In this paper, we describe the web based application vulnerabilities and implementing distinctive web vulnerability scanners to detect those severe web vulnerabilities in web applications.
The effect of BYOD adoption on job performance and work motivation

Many organizations are considering BYOD (Bring Your Own Device) programs, in which employees are permitted to use personal mobile devices for work-related purposes. Based on the Job Demands-Resources model, this study empirically investigated the effects of BYOD adoption on employees’ motivation and perceived job performance. Using a sample of 400 full-time employees from different occupational sectors in Mauritius, this study adopted Structural Equation Modelling to test the hypotheses using AMOS version 22. Results show that BYOD has a significant positive relationship with Technology Self-Efficacy, perceived workload and perceived job autonomy, while perceived job autonomy is a positive antecedent to perceived workload. In addition, Technology Self-Efficacy, perceived job autonomy and perceived workload in turn influence perceived job performance, while perceived job autonomy and perceived job performance were found to be significant determinants of work motivation. Implications of these findings, limitations and potential research avenues are also discussed.
Aeroelastic flutter energy harvesters self-polarized by triboelectric effects

This paper presents the performances of several electrostatic flutter energy harvesters tested in a wind tunnel between 0 and 20 m s−1. The main idea is to use the flutter capability of thin flexible films confined between lateral walls to induce simultaneously the capacitance variations and the electrostatic polarization required by the triboelectric/electrostatic conversion. This technology provides thin and flexible devices and solve the electret’s stability issue (Perez et al 2015 Smart Mater. Struct., Perez et al 2015 New Circuits and Systems). Our prototypes (<16 cm2) have a quick startup (from 3 m s−1) and an electrical power-flux density from 0.35 μW cm−2@3 m s−1 (light breeze) to 35 μW cm−2@20 m s−1 (fresh gale). A Maximum Power Point circuit has been developed to efficiently use the power provided by the energy harvesters. The energy harvester combined with its power management circuit has finally been used to supply an 868 MHz wireless sensor node with temperature and acceleration measurements, validating the complete energy harvesting chain.
Effect of Artemisia herb on induced hyperglycemia in wistar rats

The study was carried out to evaluate the hypoglycemic effect of Artemisia herb aqueous extract on postprandial blood glucose in normoglycemic and dexamethasone-induced hyperglycemic wistar rats. Sixty adult male wistar rats were used; rats were assigned to six equal groups (10 per each). Hyperglycemia had been induced in 40 rats by injection of single dose of dexamethasone (8 mg/2 ml, s.c.). Normal groups drenched the herb extract orally and with drinking water in 100%, and 50% concentration (NA100%, NA50%) respectively. After induction and ensuring of hyperglycemia, distil water (DW), and the (PIA100%, PIA50%) treated groups with herb extract 100%, 50% concentration respectively, finally the (M) group (metformin 500mg/ml) was treated by drenched with metformin 500 mg orally for 10 consecutive days for all group. Results were revealed that drenching of Artemisia herba- alba herb 100% aqueous extract has a highly significant (p<0.01) hypoglycemic effect on postprandial blood glucose in both normoglycemic and hyperglycemic rats comparing to normal values and to metformin respectively, whereas hypoglycaemic effect of Ah extract 50% was significant (p<0.05) on postprandial blood glucose in normoglycemic rats comparing to normal values and highly significant (p<0.01) in hyperglycemic rats comparing to metformin. It can be concluded that drenching of aqueous extract of Ah has potent hypoglycemic effect
Information needs and seeking behavior of Pakistani Physicians Information needs and seeking behavior of Pakistani Physicians

This paper aims to investigate the information need and seeking behaviour of physicians working in a well-reputed Lahore based hospital. Identification of medical professionals’ existing problems related to information searching and retrieval from the hospital library was another main objective of this study. A quantitative research approach is utilized to conduct this study and a cross-sectional survey research method is used to collect data on a self-reporting questionnaire. A total 226 medical doctors working in a Lahore based hospital participated in the survey. The findings of the study revealed that majority of the participants accessed the library information resources to keep themselves up-to-date with the professional developments and for the purpose of their continuing education. Moreover, majority of the respondents preferred print sources to fulfil their information needs. Problems, as well as suggestions are also presented in the study. This is the first study in nature which is conducted on medical doctors of a well- reputed Lahore based hospital to know their information needs, seeking behaviour and problems. Findings may be useful for the organizations offering medical services and library administration to better understand and meet the information need, seeking behaviour and problems of physicians which, as a result, might help physicians offer state-of-the-art services to patients and earn a good repute for their organization.
A Constructivist Grounded Theory of Trust in Agile Scrum Teams

— As Scrum is predominantly a team-based activity, it is consequently an intensely social endeavour. In order to deliver on the mutually agreed goals of the Sprint, Scrum teams need to collaborate and share knowledge effectively. Many authors have cited trust as being crucial to fostering collaboration and knowledge sharing. However, to date there has been no published research into this crucial social construct in the context of agile software development teams. This paper revisits the conceptual model of trust presented at SOFTENG 2018 in light of the findings from a preliminary Constructivist Grounded Theory study conducted on two Scrum teams in a major multinational software development company in the West of Ireland.
Improving Recovery: A Concentrate Management Strategy for Inland Desalination

Anti-scalant degradation by peroxone (the combination of hydrogen peroxide and ozone) is difficult to measure directly, since analytical techniques for direct measurement of the anti-scalant are unknown. Although we have made progress on developing a direct measurement technique, we have not yet been completely successful. As a result, we use indirect methods of analysis—either measuring the total organic carbon (TOC) or, for phosphonate-based anti-scalants, the phosphate released into the water. The latter is more successful because the TOC measure cannot differentiate by-products from the partial oxidation of the anti-scalant (and these by-products might have none of the original anti-scalant properties remaining) from the raw anti-scalant. A few recent results from one of the anti-scalants we are studying are described here.
IMPACT OF VOCATIONAL EDUCATION AND TRAINING ON EMPLOYMENT: AN EMPIRICAL STUDY IN THE NORTHERN PROVINCE OF SRI LANKA

This paper studies the impact of vocational education and training (VET) on the probability of getting job. 4562 individuals who were randomly selected for annual labor force survey were included in this study. Nearest - neighbor matching method has been ch osen for this study. The result of this study shows that VET increases the probability of getting job by 17 percent. The logit model for participation in VET indicates that the probability of participating in VET by a female student is lower than that of a male student and also the probability to participating in VET increase with schooling and decrease with age. This study suggests that more students should be admitted to the VET programme and government authority should encourage and motivate school children, especially female students, to enroll in VET programme.
Validating the Breathing Vigilance Questionnaire for use in dysfunctional breathing

Background Dysfunctional breathing is common among people with and without primary respiratory pathology. While anxiety can contribute to dysfunctional breathing, the underpinning mechanism is unclear. One explanation is that anxiety induces conscious, vigilant monitoring of breathing, disrupting “automatic” breathing mechanics. We validated a new tool that quantifies such breathing-related “vigilance”: the Breathing Vigilance Questionnaire (Breathe-VQ). Methods 323 healthy adults (mean (range) age 27.3 (18–71) years; 161 males) were analysed. We developed an initial Breathe-VQ (11 items, 1–5 Likert scale) based on the Pain Vigilance and Awareness Scale, using feedback from the target population and clinicians. At baseline, participants completed the Breathe-VQ, Nijmegen Questionnaire (NQ), State-Trait Anxiety Inventory form 2 and Movement-Specific Reinvestment Scale (assessing general conscious processing). 83 people repeated the Breathe-VQ 3 weeks later. Results Five items were removed based on item-level analysis. The resulting six-item Breathe-VQ questionnaire (score range 6–30) has excellent internal (α=0.892) and test–retest reliability (intraclass correlation 0.810), a minimal detectable change of 6.5 and no floor/ceiling effects. Validity was evidenced by significant positive correlations with trait anxiety and conscious processing scores (r=0.35–0.46). Participants at high risk of having dysfunctional breathing (NQ >23; n=76) had significantly higher Breathe-VQ score (mean±sd 19.1±5.0) than low-risk peers (n=225; mean±sd 13.8±5.4; p<0.001). In this “high risk of dysfunctional breathing” group, Breathe-VQ and NQ scores were significantly associated (p=0.005), even when controlling for risk factors (e.g. trait anxiety). Conclusions The Breathe-VQ is a valid and reliable tool to measure breathing vigilance. High breathing vigilance may contribute to dysfunctional breathing and could represent a therapeutic target. Further research is warranted to test Breathe-VQ's prognostic value and assess intervention effects. Anxious, vigilant monitoring of breathing may contribute to dysfunctional breathing. A short self-reported outcome measure is validated that allows researchers and clinicians to measure how much individuals display such breathing-specific vigilance. http://bit.ly/3JTs57Y
Growth Factor Receptor Vaccine Based on Xenogeneic Epidermal Immunogene Therapy of Tumors with

The breaking of immune tolerance against self epidermal growth factor receptor (EGFr) should be a useful approach for the treatment of receptor-positive tumors with active immunization. To test this concept, we constructed a plasmid DNA encoding extracellular domain of xenogeneic (human) EGFr (hEe-p) or corresponding control mouse EGFr (mEe-p) and empty vector (c-p). Mice immunized with hEe-p showed both protective and therapeutic antitumor activity against EGFr-positive tumor. Sera isolated from the hEe-p-immunized mice exhibited positive staining for EGFr-positive tumor cells in ﬂow cytometric analysis and recognized a single 170-kDa band in Western blot analysis. Ig subclasses responded to rEGFr proteins were elevated in IgG1, Ig2a, and Ig2b. There was the deposition of IgG on the tumor cells. Adoptive transfer of the puriﬁed Igs showed the antitumor activity. The increased killing activity of CTL against EGFr-positive tumor cells could be blocked by anti-CD8 or anti-MHC class I mAb. In vivo depletion of CD4 (cid:1) T lymphocytes could completely abrogate the antitumor activity, whereas the depletion of CD8 (cid:1) cells showed partial abrogation. The adoptive transfer of CD4-depleted (CD8 (cid:1) ) or CD8-depleted (CD4 (cid:1) ) T lymphocytes isolated from mice immunized with hEe-p vaccine showed the antitumor activity. In addition, the increase in level of both IFN- (cid:2) EGFr a homologous