Miracle-dz/UniFAR-FTUs huggingface dataset:
Dance for Parkinson's

This chapter aims to present important aspects of dance for people with Parkinson's disease and the benefits of dance practice for cognition and quality of life in this population. In the first part, the context of the topic addressed was explained, presenting the main characteristics of the disease and the main contributions of dance for people with Parkinson's disease. The available literature on the impacts of dance on cognition for this population was presented and discussed. After, the findings related to the potential of dance for the population's quality of life are demonstrated and commented on. In the end, the main results found are pointed out. Although some studies did not show significant improvements in these aspects, dance practice seems to be efficient to improve cognition, mainly executive function, and increasing quality of life in people with Parkinson's disease.
Enabling live-cell super-resolution microscopy by computational analysis and fluorescent probe design.

Super-resolution fluorescence microscopy has become a well-established tool for structural cell biology, achieving lateral resolutions on molecular scales. Limitations to the application of super-resolution in live-cell imaging remain however. Particularly, the requirement for intense phototoxic illumination, prolonged acquisition times, non-physiological media and extensive computational analysis. This thesis aims to address these issues, through both analytical and biochemical approaches. Three analytical methods are presented and evaluated, including a method for nano-meter precision microtubule end tracking applicable to live-cells, and a Hidden Markov model of fluorophore photoswitching, for use in live-cell experimental design. The third, Super-Resolution Radial Fluctuations (SRRF), is a novel image processing algorithm that forms the basis of a new approach to live-cell super-resolution. Low-illumination, live-cell imaging of actin dynamics in T-cell synapses at resolutions better than 100 nm are demonstrated in physiologically relevant media using SRRF. In addition, SRRF enables super-resolution in modern widefield or confocal microscopes using conventional fluorophores with illumination orders of magnitude lower than methods such as single molecule localisation or stimulated emission depletion. The computational framework developed for SRRF, NanoJ, is an open-source java library of high performance algorithms that has enabled the development of a number of GPU accelerated ImageJ/FIJI plugins for super-resolution. While SRRF allows super-resolution in live-cells, achieving resolutions on the order of 10s of nm remains challenging. To this end, Super-Beacons (SBs), novel DNA-based super-resolution probes that photoswitch spontaneously under environments relevant for live-cell imaging, are presented. The design of SBs allows the engineering of photoswitching within the physical environment of the cell, mediated through structural, chemical or thermal control. Single molecule imaging and characterisation of the photoswitching of the probes is performed. The use of SBs is verified in fixed-cell imaging of benchmark structures and live-cell super-resolution of interferon inducible transmembrane proteins is demonstrated resolving the endosomal membrane with 65 nm resolution.
Imaging of Focused Ultrasound-Induced Shear Waves to Probe Mechanical Anisotropy of Tissue

It is important to understand mechanical anisotropy in fibrous soft tissues because of the relationship of anisotropy to tissue function, and because anisotropy may change due to injury and disease. We have developed a method to noninvasively investigate anisotropy, based on MR imaging of harmonic ultrasound-induced motion (MR-HUM), using focused ultrasound (FUS) and magnetic resonance elastography (MRE). MR-HUM produces symmetric, radial waves inside a tissue, which enables a simple assessment of anisotropy using features of the resulting shear wave fields. This method was applied to characterize ex vivo muscle tissue, which is known to exhibit mechanical anisotropy. Finite element (FE) simulations of the experiment were performed to illustrate and validate the approach. Anisotropy was characterized by ratios of apparent shear moduli and strain components in different directions.
The impact of some morphological and motor characteristics in short distance running

The knowledge of morphological development and their impact on motor skills in short-distance athletes should be one of the main concerns of athletics coaches, because any scientific research in the field of physical culture and sports is about proving the development and evaluation of anthropological characteristics which are responsible for achieving success in athletics. The purpose of this paper is to confirm the impact of some anthropometric characteristics in the execution of running speeds on short distances, specifically in running at 100, 200 and 400 meters to students aged 18 ± 6 years of the Faculty of Physical Education and Sports in Prishtina. The sample of this research has included a total of 60 students aged 18 years of the Faculty of Physical Education and Sports in Prishtina. The measurements were executed during September in the hall of the Faculty, while the 100, 200, and 400 meter runs in the stadium "Fadil Vokrri" Prishtina. The only condition that was used during the determination of the sample was: that the students are involved in regular physical education classes (and on the day of the measurement be healthy, without the flu, cold or other symptoms). The variables which are applied in this research have been 8 anthropometric variables and 3 motor-specific variables. The results obtained after their processing indicate that the impact of anthropometric variables is higher in running at 100, 200 and 400 meters. Short distance running and long distance running reduces the impact of anthropometric parameters whereas the influence of metabolic factors of energy production is increased. These results were also confirmed using regression analysis, so that groups of predictors of anthropometric characteristics, specific motor skills that statistically significantly influenced each variable of individual criteria. The world records below the 10-second limit, in the 100 m, near the 9-meter limit, show not only the high level of sports, but also the strong impact on the growth, especially of strength indicators, speed-strength, explosive force, as main and applied motor skills in sports and athlete’s everyday life.
Investigating the Priorities of Youth for the Selection of Media for News Consumption

This study examined the priority of a young generation regarding the selection of medium for news consumption of Multan city. The rationale of the research was to explore the authority of Social Networking Medium (SNM) and explored the comparison between both genders about the consumption of media for repeated information seeking. Moreover, a survey questionnaire methodology used to explore the priorities of the youth and the sample size was five hundred in total using the purposive sampling technique. The study gave a clear hint that the use of Social Networking Medium (SNM) for news acquiring was 56 percent which is greater than the traditional media (print media), which was 44 percent. The study also pinned the point that the youth is consuming the newspaper for relevant information more than Facebook. Overall findings of the study illustrated that Social Network Medium (SNM) is the foremost source of news and information among the youth of Multan.
Displaying character strengths in behavior is related to well-being and achievement at school: Evidence from between- and within-person analyses

ABSTRACT In two studies, we establish the association between different assessments of character strengths (i.e., traits, habitual and daily behavior at school) with school-related well-being and achievement. Study 1 (N = 414, mean age = 14.14 years) demonstrated that habitual strengths-related behavior at school accounted for unique variance in well-being at school and in achievement beyond the influence of the respective character strength trait. Further, the desirability of certain strengths (e.g., perseverance, fairness, forgiveness, and humor) at the classroom level accounted for additional variance in students’ well-being. Study 2 (N = 186, mean age = 14.27 years) used a diary design across five days to replicate the between-person associations and study within-person associations. Results revealed that daily strengths-related behavior predicted well-being on the following day. Overall, the results underline the importance of strengths-related behavior at school and suggest that all 24 character strengths are relevant for well-being at school.
Shrinking core model of demineralization of chitin isolation from shrimp shell

Chitin is a naturally abundant polymer and most of it was used as a surfactant and cosmetic raw materials. Chitin be able to derive from natural sources like shrimp shell waste. The aim of this research was to study the kinetic model of chitin demineralization with approach to shrinking core model (SCM) with variation of hydrochloric acid concentration. There models were used: Fluid Film Layer Diffusion, Ash Layer Diffusion and Chemical Reaction. It was began with deproteination at first with NaOH 3,5 % and continued with demineralization using hydrochloric acid at concentration 0,3 N; 0,6 N; 0,9 N and 1,2 N with variation of reaction time at 15, 30 and 15 minute. The calcium content in the product was analyzed after it was dried in the air oven. The results showed calcium concentration decrease along with increasing of hydrochloric acid concentration. It get kinetic model at concentration 0,3 N of hydrochloric acid usage with form:with the highest value of R 2 is 0,9555 and the smallest percentage error is 5,92%. Meanwhile with usage of hydrochloric acid at concentration 0,6 N; 0,9 N and 1,2 N were get kinetic model with form:with the highest value of R 2 is 0,9794.
HALITOSE: CONHECIMENTO DE GRADUANDOS ACERCA DO DIAGNÓSTICO E TRATAMENTO EM UM CURSO GRADUAÇÃO EM ODONTOLOGIA DA BAHIA, BRASIL

A halitose é um problema que pode causar desconforto nas relações sociais, danosemocionais e afetar a imagem pessoal. Este problema acomete 30 a 50% da populaçãoadulta mundial, entretanto seu diagnóstico nem sempre é executado pelo profissional dasaúde e seu tratamento ou a falta dele pode frustar esta categoria de pacientes (Seemanet al., 2014).
Interdisciplinary Development of a Transdiagnostic Mobile App to Enhance Children’s Emotion Regulation: Sharing Insights and Lessons Learned

Background: Digital interventions, including mobile apps represent promising means to provide effective mental health support to young people. Despite the increased availability of mental health apps, there is a significant gap for this age group, especially for younger children. Research investigating the effectiveness and development process of child mental health apps is limited, and the field faces persistent issues in relation to low user up-take and engagement, which is assumed to be a result of lackinginterdisciplinary approaches.Objective: We present the development and design process of a new mental health app for children that targets their emotion regulation abilities. We describe the creation of a new interdisciplinary development framework, to guide the design process, and explain how each activity informed different app features.Methods: The first two stages of the framework employed a variety of methods, including: 1) classroom observations, 2)public-engagement events with the target group (N=21), 3) synthesis of the existing evidence as part of a meta-analysis, 4) a series of co-design and participatory workshops with young users (N=33), clinicians (N=7), researchers (N=12), app developers (N=1) , designers (N=2), and lastly 5) testing of the first high-tech prototype (N=15). Results: For the interdisciplinary framework we drew on methods derived from the medical research council framework for complex interventions, the patient-clinician-framework and Druin’s cooperative inquiry. The classroom observations, public-engagement events, and synthesis of the existing evidence informed the first key pillars of the app and wireframes. Subsequently, a series of workshops shaped and reshaped the content and app features, including games, psychoeducational films, and practice modules. Based on the prototype testing sessions we made further adjustments to improve the app.Conclusions: Although mobile apps could be highly suitable to support young people’s mental health on a wider scale, there is little guidance on how these interventions could be designed. The involvement of the different methods and especially the young users was very valuable. We hope that the interdisciplinary framework and multiple methods that we applied will be helpful to others who are also aiming to develop suitable apps for young people.
An Investigation into Transfer Effect of Brain Cognitive Training Contents with Text Network Analysis

In this paper, we aimed to analyze the transfer effect between cognitive areas using Computerized Cognitive Training (CCT). As a way to achieve goals, pieces of literature that have the effect of improving cognitive functions using CCT for Mild Cognitive Impairment (MCI) were collected from four research databases and performed analysis of the centrality based on text networks. As a result, the comparative experimental studies that used computers and video games together as a training tool accounted for the most, and memory accounted for most of the cognitive domain targeted by the training, and a variety of contents were performed for it. The most frequent memory training method was N-Back and, the contents with the highest centrality index was the memory area, and video was the highest as a tool of intervention. In particular, memory content and attention content were more than double the different with 33 points and 16 points. However, index of closeness centrality was found to be derived relatively similar scores at 0.387, 0.381. It can be interpreted that the possibility of the transfer effect occurring from memory and attention areas since the training process between the two content is similar.
FOXD1 Promotes EMT and Cell Stemness of Head and Neck Squamous Cell Carcinoma by Transcriptional Activation of SNAI2

BackgroundEpithelial-mesenchymal transition (EMT) and cell stemness are implicated in the initiation and progression of head and neck squamous cell carcinoma (HNSCC). Revealing the intrinsic regulatory mechanism may provide effective therapeutic targets for HNSCC.ResultsIn this study, we found Forkhead box D1 (FOXD1) was upregulated in HNSCC when compared with normal samples. Patients with higher FOXD1 expression had poorer overall survival and disease-free survival. Immunohistochemistry results showed that FOXD1 expression was related to the clinical stage and relapse status of HNSCC patients. When knockdown the expression of FOXD1 in CAL27 and SCC25 cells, the migration, invasion, colony formation, sphere formation, and proliferation abilities decreased. Moreover, the EMT and stemness-related markers changed remarkably, which indicated the EMT process and cell stemness were inhibited. Conversely, overexpression of FOXD1 promoted EMT and cell stemness. Further study demonstrated that FOXD1 could bind to the promoter region and activate the transcription of SNAI2. The elevated SNAI2, in turn, affected the EMT and cell stemness. The in vivo study showed FOXD1 overexpressed CAL27 cells possessed stronger tumorigenic ability.ConclusionsOur findings revealed a novel mechanism in regulating EMT and cell stemness, and proposed FOXD1 as a potential marker for diagnosis and treatment of HNSCC.
MAIN DIFFICULTIES IN TRANSLATING CONTRACTUAL DOCUMENTATION (ENGLISH/RUSSIAN)

The article is devoted to one of the most common translation problems in the sphere of law, namely finding the adequate equivalents in vocabulary, especially it concerns foreign terminology, in grammar and in text structure. While it is well-known that equivalence is one of the key concepts in translation, the research on practical applications of this principle in different professional spheres is still limited. With the rise of the interest to the machine translation, the special attention to the most common translation problems in the sphere of law can contribute to the overall understanding of the translation process. The methodological approach taken in this study is a mixed methodology based on comparative, structural, socio-linguistic and socio-cultural aspects of translation. The material presented in the article is based on the original contracts developed in English and Russian for the major oil and gas projects to be implemented in Russia 2006-2009. The examples of vocabulary, grammar and text structures equivalents can show the reasons for emergence of the main translation difficulties - polysemantic structure of some terms, absence of concept in either language, dependence of the meaning of the term on the context, idiomatic expressions, historically established traditions in legal text formation – emphasizing the idea that equivalence principle should be considered as a priority when translating contractual documentation.
Professional Institutional Engagement as a Framework for Negotiating Space for Teacher Autonomy in Authoritarian Work Environments

Teacher involvement in decision making at school leads to increased motivation, engagement and empowerment. Using the Participatory Action Research (PAR) framework to increase opportunities for teacher participation in school affairs, we found that traditional hierarchical power relations and bureaucracy are barriers to teachers’ autonomy, participation and engagement in the day-to-day decision making process. The conceptual model of Professional Institutional Engagement (PIE) was used to enable teachers to frame the challenges to autonomy and decision making within their professional practice, craft interventional strategies to mitigate them, which included open communication, reflection and dialogue within the school environment. The results highlighted that PIE provided a practical mechanism through which traditional hierarchical relations and bureaucracies were circumvented, resulting in increased collaboration, improved institutional communication; which motivated and engaged teachers.ResumeL’engagement des enseignants dans le processus de prise de decision a l’ecole conduit a une augmentation de motivation, engagement et affranchissement. Faisant usage du cadre de Recherche d’Action Participative (RAP) dans le but d’augmenter les opportunites pour la participation des enseignants dans la gestion de l’ecole, nous avons trouve que les hierarchies traditionnelles de relations de pouvoir ainsi que la bureaucratie sont des barrieres a l’autonomie, participation et engagement des enseignants dans le processus quotidien de prise de decision. Le modele conceptuel d’Engagement Institutionnel Professionnel (EIP) fut utilise pour permettre aux enseignants de formuler les defis a l’autonomie et processus de prise de decision dans leur pratique professionnel, d’elaborer des strategies interventionnelles pour les mitiger, incluant la communication ouverte, reflexion et dialogue dans le milieu scolaire. Les resultats ont montre que EIP a fourni un mecanisme pratique a travers duquel les relations hierarchiques traditionnelles ainsi que bureaucraties etaient depassees, resultant ainsi en une grande collaboration et une communication institutionnelle amelioree, chose qui avait motive et engage les enseignants.
Theoretical study on interactions between lignocellulose components and ionic liquids

Interactions between lignocellulose and ionic liquids have been studied by designed lignocellulose components models, and their complexes with 1-butyl-3-methylimidazolium chloride. All the structures were optimized by DFT methods and hydrogen bonds within lignocelluloses components, and their complexes with 1-butyl-3-methylimidazolium chloride were investigated by AIM calculations. Our calculated results demonstrate that when dissolved in ionic liquids, the stable intermolecular hydrogen bonds and weak π-stacking interactions between ionic liquids and lignocelluloses components reduce the energy of complex systems, which are advantageous for lignocelluloses components dissolution in ionic liquids. Moreover, there are deformation accrued for both lignocelluloses components and ionic liquids, which may be a prerequisite for lignocelluloses components dissolution in ionic liquids.
INTRODUCTION: Modern dentistry is being practiced worldwide in present time, which has provided multiple treatment option to the patient for prevention and maintenance of an esthetic and functional treatment. The mandibular molars are the rst

Modern dentistry is being practiced worldwide in present time, which has provided multiple treatment option to the patient for prevention and maintenance of an esthetic and functional treatment. The mandibular molars are the rst 1 permanent molar teeth to erupt having a high susceptibility to dental caries and Periodontal diseases that necessitates maintenance of oral hygiene, failing of which can leads to complications like pulpal and periodontal involvement, furcation involvement, bone loss and eventually tooth loss.
Social lives: glimpse of online & offline expressions in young adults

The present information age and rapid expansions of social media networks have provided an interesting picture of online lives. The coronavirus pandemic came up all of a sudden, affecting us enormously. Various legal and moral steps such as lockdowns, social distancing, and quarantine were employed to combat the dreadful virus. This has forced people to stay home, others stranded in between. Lack of social interaction raises the concern of mental health issues, social isolation, and feeling of loneliness. In such tough times, social media came out as a space for obtaining information whether regarding COVID-19, health updates of people getting infected, and other helpful ways to be safe. However, on the other side, there was chaos, mass mayhem, and uncertainties due to fake news, insensitive statements, and disturbing visuals of deaths. All these emotional surges found a way of expression online. Instagram recently completed its 10th birthday and presented itself as a great platform for interaction, updates, and engagements for its users. The field of online expressions is recent yet significant especially during the times of offline restriction of movements and expressions. The article further draws upon the three theoretical approaches, namely, symbolic interactionism, de-individuation, and SIDS, out of which the first can provide a glimpse of how face-to-face interaction during the pre-pandemic times helped individuals make meaning with the world. The latter two understand how group dynamics can affect individual participation in such interaction, especially in virtual spaces.