Miracle-dz/UniFAR-FTUs huggingface dataset:
Faktor Yang Berhubungan Dengan Persepsi Masyarakat Terhadap Penerimaan Vaksinasi Covid-19 Tahap Iii (Booster) Di Desa Watan Rumpiatahun 2023

Penerimaan vaksinasi COVID-19 tahap III (booster) di tiap kabupaten/kota di Provinsi Sulawesi Selatan memperoleh cakupan yang berbeda-beda. Jika dibandingkan dengan kabupaten/kota lainnya, Kabupaten Wajo memperoleh cakupan vaksin COVID-19 tahap III (booster) masih rendah yaitu 14.06%, Desa Watan Rumpia persentase cakupan vaksinasi COVID-19 tahap III (booster) per 16 Agustus 2022 adalah 55 jiwa (0.04%). Hal ini bisa jadi disebabkan karena persepsi dari masyarakat itu sendiri dalam menanggapi penerimaan vaksinasi COVID-19 tahap III (booster). Penelitian ini bertujuan untuk mengetahui hubungan antara persepsi masyarakat mengenai hambatan, dan isyarat untuk bertindak dengan penerimaan vaksinasi COVID-19 tahap III (booster) di Desa Watan Rumpia, Kabupaten Wajo tahun 2023. Desain penelitian yang digunakan yaitu observasional analitik dengan rancangan cross sectional. Populasi dalam penelitian ini adalah masyarakat yang telah menerima vaksin tahap II dengan usia 18 tahun sampai lansia (60-74 tahun) yang berdomisili di Desa Watan Rumpia dengan jumlah 182 orang, jumlah sampel dalam penelitian ini yaitu 125 responden. Teknik penarikan sampel yang digunakan adalah simple random sampling. Analisis data secara univariat dan bivariat yang menggunakan uji chi square. Dengan tingkat kepercayaan 95%. Hasil penelitian menunjukkan bahwa terdapat hubungan antara persepsi hambatan (ρ-value = 0.014), isyarat untuk bertindak (ρ-value = 0.008) dengan penerimaan vaksinasi COVID-19 tahap III (booster). Kata Kunci : Penerimaan Vaksinasi COVID-19 tahap III (booster), persepsi hambatan, isyarat untuk bertindak.
[Children's mental health: a priority to consider].

OBJECTIVE To Identify possible changes in the frequency of psychopathological syndromes in Mexican children population over a 15-year period using the Brief Screening and Diagnostic Questionnaire (CBTD in Spanish). MATERIALS AND METHODS Information gathered from different studies on the general population, schools and medical general practice are analyzed. Results from the Mexico City study were used as base rates for comparisons. RESULTS Higher prevalence of externalizing syndromes such as attention deficit and hyperactivity, oppositional and explosive conduct were very evident. Also, anxiety and depressive syndromes showed a notable increase. Prevalence of abnormal language and probable epilepsy were also increased on different age-groups. CONCLUSIONS Findings are discussed in light of longitudinal reports in the literature as well as on reports in adolescent population in Mexico.
A Comparison of Passive Microwave Emission Models for Estimating Brightness Temperature at L- and P-Bands Under Bare and Vegetated Soil Conditions

P-band radiometry has been demonstrated to have a deeper sensing depth than L-band, making the consideration of multilayer microwave interactions necessary. In addition, the scattering and phase interference effects are different at the P-band, requiring a reconsideration of the need for coherent models. However, the impact remains to be clarified, and understanding the validity and limitations of these models at both L- and P-bands is crucial for their refinement and application. Therefore, two general categories of microwave emission models, including two stratified coherent models (Njoku and Wilhite) and four incoherent models (conventional tau-omega model and three multilayer models being zero-order, first-order, and incoherent solution), were intercompared for the first time on the same dataset. This evaluation utilized observations of L- and P-bands radiometry under different land cover conditions from a tower-based experiment in Victoria, Australia. Model estimations of brightness temperature (TB) were consistent with measurements, with the lowest root mean square error (RMSE) at P-band V-polarization under corn (2 K) and the highest RMSE at L-band H-polarization under bare soil (13 K). Coherent models performed slightly better than incoherent models under bare soil (3 K less RMSE), while the opposite was true under vegetated soil conditions (1 K less RMSE). Coherent and incoherent models showed maximum differences (3 K at P-band and 2 K at L-band), correlating strongly with soil moisture variations at 0–10 cm. Findings suggest that coherent and incoherent models performed similarly; thus, incoherent models may be preferable for estimating TB at L- and P-bands due to reduced computational complexity.
A Review on Metabolic Dysfunction Hypothesis of Alzheimer's Disease

: Alzheimer's disease (AD) remains a formidable challenge in the field of neurodegenerative disorders. This complex disease characterized by progressive cognitive decline and the accumulation of amyloid-beta (Aβ) plaques and neurofibrillary tangles in the brain, leading to progressive cognitive decline and synaptic dysfunction. While the amyloid cascade hypothesis has long dominated the field, emerging evidence suggests a crucial role for metabolic dysfunction in the pathogenesis of AD. The Metabolic Dysfunction Hypothesis posits that disruptions in energy metabolism, including glucose metabolism and mitochondrial function, contribute significantly to the development and progression of AD. This review aims to comprehensively explore the molecular and cellular aspects of the Metabolic Dysfunction Hypothesis, shedding light on the intricate interplay between metabolic disturbances and neurodegeneration in AD.
Exploring the Role of Intraoperative Positive Culture of Allograft Bone in Subsequent Postoperative Infections among Donors and Recipients in Bone Bank Processing

Background: Allografts have been frequently used in orthopedic procedures. The purposes of this study were to evaluate the discard rates and bacterial contamination of a bone bank, and to assess the clinical outcomes of recipients with bacterial culture-positive donor allografts. Methods: We retrospectively reviewed 1764 allografts which were harvested from living donors and stored in a bone bank from 2018 to 2022. The donors whose allografts displayed bacterial contamination at retrieval of the primary hip or knee arthroplasty were followed for microbiology and subsequent prosthetic joint infection analysis. The infected pathogens, antibiotic treatment and subsequent infection were reviewed for the intraoperative positive culture group. Results: The discard rate was 17%, and the bacterial contamination rate of bone retrieval was 2.15%. Thirty-eight allografts at retrieval displayed confirmed bacterial growth, and 37 patients did not reveal infective signs at 6 months follow-up. A total of 1464 allografts were stored and implanted, among which 28 allografts (1.91%) were confirmed to be positive for bacterial growth and 13 cases (0.89%) were confirmed as surgical site infections. Conclusions: Our results validate the suggestion that our bone bank system performs good quality monitoring to eliminate the risk of dissemination of viral and bacterial diseases and to decrease surgical site infection after allograft implantation. By ensuring aseptic conditions and contamination-reducing strategies during harvesting and thawing, the allografts can be safely stored and implanted while limiting bacterial contamination. Our findings confirm that the intraoperative positive cultures of allografts did not contribute to subsequent postoperative surgical site infection in donors and recipients.
Chitosan-Coated Azithromycin/Ciprofloxacin-Loaded Polycaprolactone Nanoparticles: A Characterization and Potency Study

Purpose Antimicrobial resistance is a major health hazard worldwide. Combining azithromycin (AZ) and ciprofloxacin (CIP) in one drug delivery system was proposed to boost their antibacterial activity and overcome resistance. This study aims to improve azithromycin and ciprofloxacin activity by co-encapsulating them inside chitosan-coated polymeric nanoparticles and evaluating their antibacterial activity. Methods The double emulsion method was employed to co-encapsulate AZ/CIP inside chitosan-coated polymeric nanoparticles. The formulations were evaluated for their nanoparticle size, size distribution, and zeta potential. Differential scanning calorimetry (DSC) analysis characterized the formula’s thermal sustainability. Encapsulation efficiency was measured by HPLC and spectrophotometric analysis. Morphological studies used the Transmission Electron Microscopy (TEM). The in vitro release profiles of both AZ and CIP were monitored utilizing the dialysis membrane bag method. The micro-dilution assay assessed the antimicrobial activity against a clinical isolate of Klebsiella pneumoniae. Results The prepared AZ/CIP-poly-caprolactone nanoparticles were spherical; their size range was 184.0 ± 3.3–190.4 ± 5.6 nm and had high size uniformity (poly-dispersity index below 0.2). The zeta potential ranged from −21.2 ± 2.4 to −27.0 ± 2.5 mV, while chitosan-coated nanoparticles showed a positive zeta potential value ranging from 8 to 11 mV. The thermal study confirmed the amorphous state of both antibiotics inside the nanoparticles. The results of the in vitro release study indicated a slow and uniform rate of release for both drugs extended over 4-days, with a faster rate in the case of AZ. The MIC values reported for both chitosan-coated NP have been tremendously reduced by at least 15 folds of pure CIP and more than 60 folds of pure AZ. Conclusion The co-encapsulation of AZ/CIP into chitosan-coated polymeric nanoparticles has been successfully achieved. The produced particles showed many beneficial attributes of uniform particle sizes below 200 nm and high zeta potential values. Chitosan-coated polymeric nanoparticles extensively enhanced the antibacterial activity of both AZ/CIP against bacteria.
ANÁLISE DE MAMOGRAFIAS DE MULHERES ACIMA DE 69 ANOS

Objetivou-se analisar os resultados de mamografias de mulheres com idade igual ou superior a 70 anos realizadas em 2022 em uma clínica radiológica de uma cidade do extremo sul catarinense. Para essa finalidade, foram avaliados 699 laudos de mamografias de mulheres com idade igual ou superior a 70 anos. Foram coletadas informações relacionadas à idade e ao resultado da mamografia. Como resultado, foi encontrado a média de idade de 74,48, sendo que 10,6% das mamografias resultaram em BI-RADS 0 e 81,7% em BI-RADS 2. Dentre as pacientes com resultado sugestivo de malignidade, 1,4% delas apresentou BI-RADS 4 e 0,1% BI-RADS 5. Conclui-se que o rastreio do câncer de mama através da mamografia nas idades preconizadas pelo Ministério da Saúde é adequado e estatisticamente correto quando aplicado à população do presente estudo. Palavras-chaves: Mamografia, Neoplasias da Mama, Idoso, Mama, Doenças Mamárias, Densidade da Mama.
ICAM-1 and CRP as biomarkers of 3-month outcome in acute ischaemic stroke

Background It is clear that, inflammation deteriorates cerebral injury during the acute phase of stroke. While this process is going on, intercellular adhesion molecule-1 (ICAM-1) has a crucial role to play in mediating migration of immune cells into the damaged area. Furthermore, C reactive protein (CRP) is an essential inflammatory molecule in human organism. This research aims to investigate the association between ICAM-1, highly sensitive CRP(hs-CRP) and the prognosis of acute ischaemic stroke (AIS). Methods 118 patients with AIS who were treated at Tashkent Medical Academy were participants in this research project. Blood samples were collected from patients on an empty stomach within 24 hours of admission. Modified Rankin Scale (mRS) was used in order to assess the functional prognosis in 3 months following the case of stroke in patients. The inadequate prognosis is described as mRS≥3. Each biomarker’s potential to predict has also been evaluated with receiver operating characteristic analysis. Results ICAM-1 was identified to be an independent predictor of 3-month outcome (OR 1.05, 95 % CI 0.848 to 1.625; p=0.02) (area under the curve (AUC)=0.82 %). Independent associations with functional outcome were also found to be true for hs-CRP (OR 1.22, 95 % CI 0.78 to 1.86; p=0.03) (AUC=0.74 %). Conclusions The outcomes of a 3-month study carried out on patients with AIS showed ICAM-1 and hs-CRP to be independent predictors.
Características del crecimiento de una plantación adulta de Abies pinsapo en un sitio de Valdivia, Chile

Abies pinsapo es una especie en peligro de extinción originaria del Mediterráneo (España y Marruecos), se encuentra en Chile como ornamental, pero en Valdivia existe una plantación experimental de 42 años que permite conocer su desarrollo como especie de interés forestal. Los objetivos del trabajo fueron caracterizar el rodal dasométricamente, analizar su crecimiento en diámetro, determinar la densidad básica de la madera y caracterizar el sotobosque, el mantillo y el arraigamiento. Mediante un censo de los árboles se midieron las variables de diámetro normal y basal y se estimaron las alturas. Se evaluó el crecimiento diametral según el ancho de anillos (muestras radiales de 5 mm de diámetro) y la densidad básica de la madera en muestras radiales de 12 mm de diámetro. Además, se caracterizó el sotobosque, el suelo, el mantillo y el arraigamiento. El clima local es más húmedo y frío que en su origen, pero adecuado para la especie. El suelo es estructuralmente adecuado, pero pobre en nutrientes. El rodal presentó 1830 árboles por hectárea, área basal de 105,6 m2/ha, diámetro medio cuadrático de 27 cm, altura dominante de 22 m y densidad básica promedio de la madera de 350 kg/m3. El sotobosque cubrió 9% y el mantillo presentó 40,5 Mg/ha de materia orgánica. El arraigamiento fino alcanzó hasta 1 m de profundidad, con alta concentración superficial (50% desde 0 cm hasta 21 cm). Se concluyó que Abies pinsapo se ha desarrollado mejor en Valdivia que en su hábitat natural, que su crecimiento diametral indicó mayor estrés por competencia que por limitaciones climáticas y que su madera fue de baja densidad básica.
THE INFLUENCE OF KOUZES AND POSNER'S EXEMPLARY LEADERSHIP, SELF-REGULATION, AND JOB SATISFACTION ON TEACHER PERFORMANCE IN XYZ TANGERANG SCHOOL

Teacher performance is needed to improve school achievement, shown by the increase in students' achievement in a school environment. Teacher performance is influenced by factors or variables directly or indirectly related. This study aimed to determine the influence of Kouzes and Posner's exemplary leadership, self-regulation, and work satisfaction on teacher performance through data collection to all teachers at XYZ School Tangerang consisting of class teachers and subject teachers with a population of 32 people. The data processing technique used in this study was path analysis using a quantitative approach with the SmartPLS application program data instruments. The conclusions of the results of this study were (1) Kouzes and Posner’s exemplary leadership had a positive influence on job satisfaction, (2) self-regulation had a positive influence on job satisfaction, (3) Kouzes and Poser's exemplary leadership had no positive influence on teacher performance, (4) self-regulation had a positive influence on teacher performance, (5) job satisfaction had a positive influence on teacher performance, (6) Kouzes and Posner's exemplary leadership had a positive influence on teacher performance through job satisfaction mediation, (7) self-regulation had a positive influence on teacher performance through job satisfaction mediation. Keywords: Job satisfaction, Kouzes and Posner's exemplary leadership, Performance, Self-regulation
Eﬀicient caching in Content-Centric Networks using OpenFlow

—Content-Centric Networking (CCN) is designed for efﬁcient content dissemination and supports caching contents on the path from content providers to content consumers to improve user experience and reduce costs. However, this strategy is not optimal inside a domain. In this paper, we propose a solution to improve caching in CCN using a Software-Deﬁned Networking approach.
Integrating air quality, water and climate concerns into China's energy strategy

I ACKNOWLEDGEMENTS . III TABLE OF CONTENTS . VII CHAPTER 1: INTRODUCTION . 1 CHAPTER 2: SUBSTANTIAL AIR QUALITY AND CLIMATE CO-BENEFITS ACHIEVABLE NOW WITH INDUSTRIAL EFFICIENCY IMPROVEMENTS AND TECHNOLOGY UPGRADES IN CHINA . 7
Comparing city-scale greenhouse gas (GHG) emission accounting methods: Implementation, approximations, and policy relevance

More than 1,200 cities worldwide are embarking on low carbon goals. However, currently there are no protocols in place to consistently account for GHG emissions associated with cities. Thus, this thesis explores mathematical relationships, approximations, implementation challenges, and policy relevance for three city-scale GHG emission accounting methods: Purely Territorial, Trans-Boundary Infrastructure Supply-Chain Footprint (TBIF), and Consumption-Based Footprint (CBF). Mathematical relationships using Single-Region Input-Output, and Multi-Region InputOutput models showed that neither TBIF nor CBF provided a more holistic accounting of trans-boundary GHG. A typology of cities defined as: net-producers, net-consumers, and trade-balanced in terms of their GHGs embodied in trade is important for understanding the trans-boundary supply-chains serving cities. Data inputs for TBIF are found to be more robust and readily available, compared to CBF. A meta-analysis of 21 US cities showed that trans-boundary electricity generation, air travel, fuel refining, along with the production of food, cement, and iron & steel, may be well-suited for allocation to cities based on their use in city-wide residential-commercialindustrial activities in the TBIF method. Territorial GHGs captured as little as 37% of the total (in-boundary plus trans-boundary) footprint for net-consumer cities, and as large as 68% for net-producers. On average, TBIF captured 75% (n=2) of the total footprint for net-producers, 63% (n=11) for tradebalanced, and 62% (n=8) for net-consumer cities. In contrast, CBF captured an average of 35% (n=2), 57% (n=11), and 71% (n=8) of the total footprint for net-producers, tradebalanced, and net-consumer cities, respectively. Various metrics of GHG emissions computed for the three methods were assessed for their ability to appropriately compare cities’. For territorial GHG, neither
Role of c-Src in Carcinogenesis and Drug Resistance

Simple Summary The human body relies on essential proteins for cellular growth and development, which are synthesized according to the genetic code contained within the DNA (gene). However, if a gene malfunctions, abnormal proteins can result and lead to uncontrolled cell growth, ultimately contributing to the formation of cancerous tumors. The c-Src gene serves as a prime example of a dysregulated gene that results in the synthesis of abnormal protein that has been associated with the development of numerous types of cancer in humans. c-Src is a crucial player in the pathogenesis of cancer in both humans and other animals. It activates several proteins in cancer development, and aids established cancers in evading chemotherapeutic drugs through various mechanisms, facilitating drug resistance. Abstract The aberrant transformation of normal cells into cancer cells, known as carcinogenesis, is a complex process involving numerous genetic and molecular alterations in response to innate and environmental stimuli. The Src family kinases (SFK) are key components of signaling pathways implicated in carcinogenesis, with c-Src and its oncogenic counterpart v-Src often playing a significant role. The discovery of c-Src represents a compelling narrative highlighting groundbreaking discoveries and valuable insights into the molecular mechanisms underlying carcinogenesis. Upon oncogenic activation, c-Src activates multiple downstream signaling pathways, including the PI3K-AKT pathway, the Ras-MAPK pathway, the JAK-STAT3 pathway, and the FAK/Paxillin pathway, which are important for cell proliferation, survival, migration, invasion, metastasis, and drug resistance. In this review, we delve into the discovery of c-Src and v-Src, the structure of c-Src, and the molecular mechanisms that activate c-Src. We also focus on the various signaling pathways that c-Src employs to promote oncogenesis and resistance to chemotherapy drugs as well as molecularly targeted agents.
Exploration of Logical Meta-functions in ICLE: An Analysis of Pakistani Argumentative Essays

Systemic functional linguistics (SFL) studies how a language functions in a social context, concerning the meaning of clauses at three different levels: interpersonal, ideational, and textual. The aim of this corpus-based research is to find out the logical structures of clauses in Pakistani academic writings by evaluating two main elements of clause complexity: taxis and logico-semantics relations. For this purpose, Halliday & Matthiessen’s (2014) system of clause complexing was employed as an analytical framework. A sample size of 100 argumentative essays was taken from the ICLE corpus, which was written by Pakistani students. This corpus was annotated by using the UAM corpus tool manually. Furthermore, the comparative distributions of different types of clause complexes were studied and evaluated accordingly. It helped to identify and understand lexico-grammatical variations at the clause level in non-native Pakistani academic writings. The findings showed that Pakistani students composed hypotactic and paratactic with almost the same ratio in their writing with a minor deviation. They also tend to build different types of logico-semantic relations of clauses during the argumentation; however, the occurrences of expansion were high in contrast to projection. The null hypothesis was tested by deploying the Wilcoxon signed rank test. It revealed no significant difference between paratactic and hypotactic approaches. However, their various logico-semantic relations displayed significant differences (p<0.05).
Diltiazem Increases the Liver Regeneration in Rats by Inhibiting TGF-β1

Transforming growth factor beta-1 (TGF- β1) is the most important inhibitory cytokine during the hepatic regeneration process. Diltiazem is a Ltype calcium channel blocker that has inhibitory effect on TGF- β1. The aim of the present study was to determine the effect of diltiazem on hepatic regeneration. Sixty female Wistar Albino rats were used. Three groups were created; the control, low dose diltiazem and high dose diltiazem groups, each consisting of 20 rats. After partial liver resection (70% hepatectomy), saline was introduced to control group, 5 mg/kg diltiazem was introduced to low dose group and 15 mg/kg diltiazem to high dose group intraperitoneally. Ten rats in each group were sacrificed on the first postoperative day and the remaining rats on the fifth day. Liver weight, mitotic rate and the Ki-67 ratio were measured for determining hepatic regeneration. Liver regeneration rate on the fifth postoperative day was significantly higher both in the low dose and high dose diltiazem groups than the control group (Low diltiazem vs control: P 0.05). The Ki-67 ratio on the first postoperative day was significantly higher both in the low dose and high dose diltiazem groups than the control group (Low diltiazem vs control: P<0.001; High diltiazem vs control: P<0.001). Diltiazem increases liver regeneration by inhibiting TGF-β1.