Miracle-dz/UniFAR-FTUs huggingface dataset:
The long-term evolution of the accreting millisecond X-ray pulsar Swift J1756.9−2508

We present a timing analysis of the 2009 outburst of the accreting millisecond X-ray pulsar Swift J1756.9-2508, and a re-analysis of the 2007 outburst. The source shows a short recurrence time of only similar to 2 yr between outbursts. Thanks to the approximately 2 yr long baseline of data, we can constrain the magnetic field of the neutron star to be 0.4 x 10(8) less than or similar to B less than or similar to 9 x 10(8) G, which is within the range of typical accreting millisecond pulsars. The 2009 timing analysis allows us to put constraints on the accretion torque: the spin frequency derivative within the outburst has an upper limit of |(v) over dot| less than or similar to 3 x 10(-13) Hz s(-1) at the 95 per cent confidence level. A study of pulse profiles and their evolution during the outburst is analysed, suggesting a systematic change of shape that depends on the outburst phase. We report also the first evidence that the pulsed fractions increase with energy even if the source is in the hard state.
Thermal conductivity and sound attenuation in dilute atomic Fermi gases

We compute the thermal conductivity and sound attenuation length of a dilute atomic Fermi gas in the framework of kinetic theory. Above the critical temperature for superfluidity, T{sub c}, the quasiparticles are fermions, whereas below T{sub c}, the dominant excitations are phonons. We calculate the thermal conductivity in both cases. We find that at unitarity the thermal conductivity {kappa} in the normal phase scales as {kappa}{proportional_to}T{sup 3/2}. In the superfluid phase we find {kappa}{proportional_to}T{sup 2}. At high temperature the Prandtl number, the ratio of the momentum and thermal diffusion constants, is 2/3. The ratio increases as the temperature is lowered. As a consequence we expect sound attenuation in the normal phase just above T{sub c} to be dominated by shear viscosity. We comment on the possibility of extracting the shear viscosity of the dilute Fermi gas at unitarity using measurements of the sound absorption length.
The Spectral Properties of the Bright Fast Radio Burst Population

We examine the spectra of 23 fast radio bursts (FRBs) detected in a fly’s-eye survey with the Australian SKA Pathfinder, including those of three bursts not previously reported. The mean spectral index of (Fν ∝ να) is close to that of the Galactic pulsar population. The sample is dominated by bursts exhibiting a large degree of spectral modulation: 17 exhibit fine-scale spectral modulation with an rms exceeding 50% of the mean, with decorrelation bandwidths (half-maximum) ranging from ≈1 to 49 MHz. Most decorrelation bandwidths are an order of magnitude lower than the ≳30 MHz expected of Galactic interstellar scintillation at the Galactic latitude of the survey, . However, these bandwidths are consistent with the ∼ν4 scaling expected of diffractive scintillation when compared against the spectral structure observed in bright UTMOST FRBs detected at 843 MHz. A test of the amplitude distribution of the spectral fluctuations reveals only 12 bursts consistent at better than a 5% confidence level with the prediction of 100%-modulated diffractive scintillation. Five of six FRBs with a signal-to-noise ratio exceeding 20 are only consistent with this prediction at less than 1% confidence. Nonetheless, there is weak evidence (92%–94% confidence) of an anti-correlation between the amplitude of the spectral modulation and dispersion measure (DM), which suggests that it originates as a propagation effect. This effect is corroborated by the smoothness of the higher-DM Parkes FRBs, and could arise due to quenching of diffractive scintillation (e.g., in the interstellar medium of the host galaxy) by angular broadening in the intergalactic medium.
Effects of Polypropylene Waste Addition as Coarse Aggregates in Concrete: Experimental Characterization and Statistical Analysis

In recent times, thermoplastic waste materials are being extensively used as fine and coarse aggregates in the concrete mix as an environmentally friendly construction material. This study aims at utilizing polypropylene (PP) as a partial substitute for the conventional coarse aggregates in M30 grade concrete. The different replacement levels of coarse aggregates such as 0%, 20%, 40%, and 60% by weight were used in concrete. Sieve analysis, specific gravity, and water absorption tests were performed in all replacement levels of aggregates. The mechanical (compressive and split tensile tests) tests were conducted after 3, 14, and 28 days. The change in mechanical properties of concrete with the addition of different weight proportions of plastics was studied experimentally. Further, experimental values were predicted using the two-parameter Weibull distribution and artificial neural network (ANN)-based statistical approaches. The Levenberg–Marquardt algorithm was used in predicting the mechanical properties using the ANN. A good correlation was obtained between the experimental and predicted values with an error (%) of less than 10. The decrease in mechanical properties with the increase in replacement levels of coarse aggregates in concrete was observed in both experimental and predicted approaches. This can be attributed to poor bonding between concrete and PP aggregate owing to the development of agglomerations and the hydrophobic nature of PP. However, the strength values of 20% PP-embedded concrete specimens are closer to 0% PP-embedded concrete specimens. Therefore, 20% PP-embedded concrete specimens can be used for primary load-bearing applications to utilize plastic waste and reduce the cost of the component.
The CITA GO-ON trial: A person-centered, digital, intergenerational, and cost-effective dementia prevention multi-modal intervention model to guide strategic policies facing the demographic challenges of progressive aging

This paper presents a general overview of the CITA GO-ON study, a controlled and randomized trial aimed to demonstrate the efficacy and cost-effectiveness of a 2 years multi-modal intervention to control risk factors and change lifestyles in cognitively frail people at increased risk of dementia. In this framework, the applicability of a virtual agent to increase adherence and effectiveness (the “Go-ON digital coach”) will be explored. The multidisciplinary nature of the study brings together 7 partners including non-profit organizations, universities, technological centers and companies.
Noncommutative geometry inspired rotating black string

Noncommutativity is an idea dating back to that early times of quantum mechanics and the string theory induced noncommutative (NC) geometry provided an effective framework to study the short distance spacetime dynamics. Also, string theory, a candidate for a consistent quantum theory of gravity, admits a variety of classical black hole solutions including black strings. In this paper, we study a NC geometry inspired rotating black string to cylindrical spacetime with a source given by a smeared distribution of mass. The resulting metric is a regular everywhere, i.e. curvature-singularity free rotating black string, that in large [Formula: see text] limit interpolates Lemos black string. Thermodynamical properties of the black strings are also investigated and exact expressions for the temperature, the entropy and the heat capacity are obtained. Owing to the NC correction in the solution, the thermodynamic quantities have also been modified and that the NC geometry inspired black string is always thermodynamically stable.
Electrocaloric effect in relaxor ferroelectrics

A theoretical model for the electrocaloric effect (ECE) in relaxor ferroelectrics is presented. By solving a self-consistent relation for the ECE temperature change ΔT and minimizing numerically the mean field free energy for relaxors, the field and temperature dependence of ΔT is calculated. The corresponding harmonic Landau coefficient a=a(T), which differs from the ferroelectric case by always being positive, is derived from the spherical random bond-random field model, and the fourth-order coefficient b is treated as a phenomenological parameter, which can be either positive or negative. For b<0, a line of field-induced first-order relaxor-to-ferroelectric phase transitions exists in relaxors, which terminates at a liquid-vapor type critical point ECP,TCP. The critical behavior close to ECP,TCP is analyzed. It is shown that near the first-order phase transition a temperature or field interval or gap formally appears, where ΔT cannot be found. However, domain formation in the coexistence range should r.
A new flaring high-energy γ-ray source

We report the detection of a new gamma-ray source in the Fermi-LAT sky using a source detection tool based on the Minimal Spanning Tree algorithm. The source, not reported in previous LAT catalogues but very recently observed in the X-rays and optical bands, is characterized by an increasing gamma-ray activity in 2012 June-September, reaching a weekly peak flux of (3.3+-0.6)*10^-7 photons cm^-2 s^-1. A search for a possible counterpart provides indication that it can be associated with the radio source NVSS J141828+354250 whose optical SDSS colours are typical of a blazar.
Preparation, In Vitro and In Vivo Evaluation of Nanoemulsion In Situ Gel for Transnasal Delivery of Traditional Chinese Medicine Volatile Oil from Ligusticum sinense Oliv.cv. Chaxiong

Ischemic stroke is a difficult-to-treat brain disease that may be attributed to a limited therapeutic time window and lack of effective clinical drugs. Nasal–brain administration is characterized by low systemic toxicity and is a direct and non-invasive brain targeting route. Preliminary studies have shown that the volatile oil of Chaxiong (VOC) has an obvious anti-ischemic stroke effect. In this work, we designed a nanoemulsion thermosensitive in situ gel (VOC-NE-ISG) loaded with volatile oil of Chaxiong for ischemia via intranasal delivery to rat brain treatment of cerebral ischemic stroke. The developed VOC-NE-ISG formulation has a suitable particle size of 21.02 ± 0.25 nm and a zeta potential of −20.4 ± 1.47 mV, with good gelling ability and prolonged release of the five components of VOC. The results of in vivo pharmacokinetic studies and brain targeting studies showed that intranasal administration of VOC-NE-ISG could significantly improve the bioavailability and had excellent brain-targeting efficacy of nasal-to-brain delivery. In addition, the results of pharmacodynamics experiments showed that both VOC-NE and VOC-NE-ISG could reduce the neurological deficit score of model rats, reducing the size of cerebral infarction, with a significant effect on improving ischemic stroke. Overall, VOC-NE-ISG may be a promising intranasal nanomedicine for the effective treatment of ischemic stroke.
THE DIRECTLY IMAGED PLANET AROUND THE YOUNG SOLAR ANALOG 1RXS J160929.1 − 210524: CONFIRMATION OF COMMON PROPER MOTION, TEMPERATURE, AND MASS

Giant planets are usually thought to form within a few tens of AU of their host stars, and hence it came as a surprise when we found what appeared to be a planetary mass (∼0.008 M☉) companion around the 5 Myr old solar mass star 1RXS J160929.1 − 210524 in the Upper Scorpius association. At the time, we took the object's membership in Upper Scorpius—established from near-infrared, H- and K-band spectroscopy—and its proximity (2.″2 or 330 AU) to the primary as strong evidence for companionship, but could not verify their common proper motion. Here, we present follow-up astrometric measurements that confirm that the companion is indeed comoving with the primary star, which we interpret as evidence that it is a truly bound planetary mass companion. We also present new J-band spectroscopy and 3.0–3.8 μm photometry of the companion. Based on a comparison with model spectra, these new measurements are consistent with the previous estimate of the companion effective temperature of 1800 ± 200 K. We present a new estimate of the companion mass based on evolution models and the calculated bolometric luminosity of the companion; we obtain a value of 0.008+0.003−0.002 M☉, again consistent with our previous result. Finally, we present angular differential imaging observations of the system allowing us to rule out additional planets in the system more massive than 1 MJup, 2 MJup, and 8 MJup at projected separations larger than 3″ (∼440 AU), 0. ″7 (∼100 AU), and 0. ″35 (∼50 AU), respectively. This companion is the least massive known to date at such a large orbital distance; it shows that objects in the planetary mass range exist at orbital separations of several hundred AU, posing a serious challenge for current formation models.
A Systematic Review and Meta-Analysis of Premenstrual Syndrome with Special Emphasis on Herbal Medicine and Nutritional Supplements

Herbal medicine and nutritional supplements are suggested to treat premenstrual somatic and psycho-behavioural symptoms in clinical guidelines; nonetheless, this is at present based on poor-quality trial evidence. Hence, we aimed to design a systematic review and meta-analysis for their effectiveness in alleviating premenstrual symptoms. The published randomized controlled trials (RCTs) were extracted from Google scholar, PubMed, Scopus and PROSPERO databases. The risk of bias in randomized trials was assessed by Cochrane risk-of-bias tool. The main outcome parameters were analysed separately based on the Premenstrual Symptom Screening Tool and PMTS and DRSP scores. Secondary parameters of somatic, psychological, and behavioural subscale symptoms of PSST were also analysed. Data synthesis was performed assuming a random-effects model, and standardized mean difference (SMDs) was analysed using SPSS version 28.0. 0 (IBM, Armonk, NY, USA). A total of 754 articles were screened, and 15 RCTs were included (n = 1211 patients). Primary results for participants randomized to an intervention reported reduced PSST (n = 9), PMTS (n = 2), and DSR (n = 4) scores with (SMD = −1.44; 95% CI: −1.72 to −1.17), (SMD = −1.69; 95% CI: −3.80 to 0.42) and (SMD = 2.86; 95% CI: 1.02 to 4.69) verses comparator with substantial heterogeneity. Physical (SMD = −1.61; 95% CI = −2.56 to −0.66), behavioural (SMD = −0.60; 95% CI = −1.55 to 0.35) and mood (SMD = 0.57; 95% CI = −0.96 to 2.11) subscale symptom groupings of PSST displayed similar findings. Fifty-three studies (n = 8) were considered at low risk of bias with high quality. Mild adverse events were reported by four RCTs. Based on the existing evidence, herbal medicine and nutritional supplements may be effective and safe for PMS.
Global magnetic cycles in rapidly rotating younger suns

Abstract Observations of sun-like stars rotating faster than our current sun tend to exhibit increased magnetic activity as well as magnetic cycles spanning multiple years. Using global simulations in spherical shells to study the coupling of large-scale convection, rotation, and magnetism in a younger sun, we have probed effects of rotation on stellar dynamos and the nature of magnetic cycles. Major 3-D MHD simulations carried out at three times the current solar rotation rate reveal hydromagnetic dynamo action that yields wreaths of strong toroidal magnetic field at low latitudes, often with opposite polarity in the two hemispheres. Our recent simulations have explored behavior in systems with considerably lower diffusivities, achieved with sub-grid scale models including a dynamic Smagorinsky treatment of unresolved turbulence. The lower diffusion promotes the generation of magnetic wreaths that undergo prominent temporal variations in field strength, exhibiting global magnetic cycles that involve polarity reversals. In our least diffusive simulation, we find that magnetic buoyancy coupled with advection by convective giant cells can lead to the rise of coherent loops of magnetic field toward the top of the simulated domain.
Quantum nonexpander problem is quantum-Merlin-Arthur-complete

A quantum expander is a unital quantum channel that is rapidly mixing, has only a few Kraus operators, and can be implemented efficiently on a quantum computer. We consider the problem of estimating the mixing time (i.e., the spectral gap) of a quantum expander. We show that the problem of deciding whether a quantum channel is not rapidly mixing is a complete problem for the quantum Merlin-Arthur complexity class. This has applications to testing randomized constructions of quantum expanders and studying thermalization of open quantum systems.
1309 Differential microbial enrichment is associated with oral cancer and perineural invasion

Background Advanced oral cavity squamous cell carcinoma (OSCC) is an aggressive disease, with 5-year overall survival rates below 50%. 1 While smoking and alcohol are the most established risk factors, there is growing evidence implicating the role of the oral microbiome in promoting immunosuppres-sive states in OSCC. 2-6 The objective of this study was to evaluate the taxonomic profile of oral bacteria in advanced OSCC patients and correlate with clinicopathologic features. approved this study of patients diagnosed with treated from Samples were taken from tumor and paired adjacent normal tissues at the time of surgery and snap frozen. Demographics, clinical and pathologic information was collected. DNA from 51 samples was isolated and 16s rRNA gene sequencing was performed after PCR amplification of the V1-V3 regions of the 16s rRNA gene for paired samples. 16S rRNA sequences were processed using DADA2, implemented in QIIME2 package, and taxonomic assignments were made using RDA classifier using the Human Oral Microbiome Data-base V15.22 as the reference database. Sequencing reads proc-essing, denoising, dereplicating, chimeras filtering, and amplicon sequence variants (ASVs) generation was done using DADA2. The association between clinicopathological factors and bacterial profiles was evaluated using R Software.
Atmospheric parameters and pulsational properties for a sample of δ Sct, γ Dor and hybrid Kepler targets

We report spectroscopic observations for 19 δ Sct candidates observed by the Kepler satellite both in long and short cadence mode. For all these stars, by using spectral synthesis, we derive the effective temperature, the surface gravity and the projected rotational velocity. An equivalent spectral-type classification has been also performed for all stars in the sample. These determinations are fundamental for modelling the frequency spectra that will be extracted from the Kepler data for asteroseismic inference. For all the 19 stars, we also present periodograms obtained from Kepler data. We find that all stars show peaks in both low- (γ Dor; g-mode) and high-frequency (δ Sct; p-mode) regions. Using the amplitudes and considering 5 cycles d −1 as a boundary frequency, we classified three stars as pure γ Dor, four as γ Dor–δ hybrid Sct, five as δ Sct–γ Dor hybrid and six as pure δ Sct. The only exception is the star KIC 05296877, which we suggest could be a binary.
Risk Factors Affecting Development and Persistence of Preschool Wheezing: Consensus Document of the Emilia-Romagna Asthma (ERA) Study Group

Wheezing at preschool age (i.e., before the age of six) is common, occurring in about 30% of children before the age of three. In terms of health care burden, preschool children with wheeze show double the rate of access to the emergency department and five times the rate of hospital admissions compared with school-age asthmatics. The consensus document aims to analyse the underlying mechanisms involved in the pathogenesis of preschool wheezing and define the risk factors (i.e., allergy, atopy, infection, bronchiolitis, genetics, indoor and outdoor pollution, tobacco smoke exposure, obesity, prematurity) and the protective factors (i.e., probiotics, breastfeeding, vitamin D, influenza vaccination, non-specific immunomodulators) associated with the development of the disease in the young child. A multidisciplinary panel of experts from the Emilia-Romagna Region, Italy, addressed twelve key questions regarding managing preschool wheezing. Clinical questions have been formulated by the expert panel using the PICO format (Patients, Intervention, Comparison, Outcomes). Systematic reviews have been conducted on PubMed to answer these specific questions and formulate recommendations. The GRADE approach has been used for each selected paper to assess the quality of the evidence and the degree of recommendations. Based on a panel of experts and extensive updated literature, this consensus document provides insight into the pathogenesis, risk and protective factors associated with the development and persistence of preschool wheezing. Undoubtedly, more research is needed to improve our understanding of the disease and confirm the associations between certain factors and the risk of wheezing in early life. In addition, preventive strategies must be promoted to avoid children’s exposure to risk factors that may permanently affect respiratory health.
Detection of Neptune-size planetary candidates with CoRoT data. Comparison with the planet occurrence rate derived from Kepler

Context. The CoRoT space mission has been searching for transiting planets since the end of December 2006. It has led to the detection of about twenty Jupiter-size planets and three planets with radius R p ≲ 5 R ⊕ . The latter are CoRoT-7b, the first super-Earth observed in transit, and two validated Neptunes, CoRoT-24b and c, in a multiple system. Aims. We aim to investigate the capability of CoRoT to detect small-size transiting planets in short-period orbits, and to compare the number of CoRoT planets with 2.0 ≤ R p ≤ 4.0 R ⊕ with the occurrence rate of small-size planets provided by the distribution of Kepler planetary candidates. Methods. We performed a test that simulates transits of super-Earths and Neptunes in real CoRoT light curves of six long observational runs and searches for them blindly by using the transit detection pipeline developed at the Laboratoire d’Astrophysique de Marseille. Results. The CoRoT detection rate of planets with radius between 2 and 4 R ⊕ and orbital period P ≤ 20 days is 59% (31%) around stars brighter than r ′ = 14.0 (15.5). The vast majority of the missed planets went undetected because of a low transit signal-to-noise ratio (S/N). However, in some cases, additional instrumental or astrophysical noise may prevent even transits with relatively high S/N, i.e. S / N ≥ 10, from being revealed. By properly taking the CoRoT detection rate for Neptune-size planets (2 ≤ R p ≤ 4 R ⊕ ) and the transit probability into account, we found that according to the Kepler planet occurrence rate, CoRoT should have discovered 12 ± 2 Neptunes orbiting G and K dwarfs with P ≤ 17 days in six observational runs. This estimate must be compared with the validated Neptune CoRoT-24b and five CoRoT planetary candidates in the considered range of planetary radii, the nature of which is still unsolved. We thus found a disagreement with expectations from Kepler at 3 σ or 5 σ , assuming a blend fraction of 0% (six Neptunes) and 100% (one Neptune) for these candidates. Conclusions. This underabundance of CoRoT Neptunes with respect to Kepler may be due to a) an underestimate of the uncertainty on the Kepler planet occurrence; b) an underestimate of the false-positive probability of the Kepler small-size planetary candidates; c) an overestimate of our prediction of CoRoT Neptunes related to the number of G and K dwarfs observed by CoRoT; or d) different stellar populations probed by the two space missions. Regardless of the origin of the disagreement, which needs to be investigated in more detail, the noticeable deficiency of CoRoT Neptunes at short orbital periods seems to indirectly support the general trend found in Kepler data, i.e. that the frequency of small-size planets increases with increasing orbital periods and decreasing planet radii.