Miracle-dz/UniFAR-FTUs huggingface dataset:
Steatohepatitic variant hepatocellular carcinoma: a case report of new histological variant.

1. Vilgrain V, Boulos L, Vullierme MP, Denys A, Terris B, Menu Y. Imaging of atypical hemangiomas of the liver with pathologic correlation. Radiographics. 2000;20:379–97. 2. Kim S, Chung JJ, Kim MJ, Park S, Lee JT, Yoo HS. Atypical inside-out pattern of hepatic hemangiomas. AJR Am J Roentgenol. 2000;174:1571–4. 3. Nelson RC, Chezmar JL. Diagnostic approach to hepatic hemangiomas. Radiology. 1990;176:11–3. 4. Wittenberg J, Stark DD, Forman BH, Hahn PF, Saini S, Weissleder R, et al. Differentiation of hepatic metastases from hepatic hemangiomas and cysts by using MR imaging. AJR Am J Roentgenol. 1988;151:79–84. 5. Moody AR, Wilson SR. Atypical hepatic hemangioma: a suggestive sonographic morphology. Radiology. 1993;188:413– 7. 6. Outwater EK, Ito K, Siegelman E, Martin CE, Bhatia M, Mitchell DG. Rapidly enhancing hepatic hemangiomas at MRI: distinction from malignancies with T2-weighted images. J Magn Reson Imaging. 1997;7:1033–9. 7. Jang HJ, Kim TK, Lim HK, Park SJ, Sim JS, Kim HY, et al. Hepatic hemangioma: atypical appearances on CT, MR imaging, and sonography. AJR Am J Roentgenol. 2003;180:135–41. 8. Tsurusaki M, Kawasaki R, Yamaguchi M, Sugimoto K, Fukumoto T, Ku Y, et al. Atypical hemangioma mimicking hepatocellular carcinoma with a special note on radiological and pathological findings. Jpn J Radiol. 2009;27:156–60. 9. Hosokawa A, Maeda T, Tateishi U, Satake M, Iwata R, Ojima H, et al. Hepatic hemangioma presenting atypical radiologic findings: a case report. Radiat Med. 2005;23:371–5. 10. Matsushita M, Takehara Y, Nasu H, Hirai Y, Yamashita S, Souda K, et al. Atypically enhanced cavernous hemangiomas of the liver: centrifugal enhancement does not preclude the diagnosis of hepatic hemangioma. J Gastroenterol. 2006;41:1227–30. 11. Bartolotta TV, Taibbi A, Galia M, Lo Re G, La Grutta L, Grassi R, et al. Centrifugal (inside-out) enhancement of liver hemangiomas: a possible atypical appearance on contrastenhanced US. Eur J Radiol. 2007;64:447–55.
Essential oil composition and antioxidant activity of four Asteraceae species from Bosnia

Abstract Hydrodistilled volatile oils from Achillea millefolium L. , Arnica montana L. , Artemisia absinthium L. , and Artemisia annua L. were analyzed by GC/MS. One hundred sixty-seven compounds were identified in all samples, ranging from 74.3% to 96.4% of the total oil. A high percentage of oxygenated monoterpenes is the main characteristic of A. millefolium and A. absinthium oils with camphor (19.2%) and isoascaridol (21.9%) as the major constituents, respectively. In contrast, the main component of A. annua oil was oxygenated sesquiterpene selina-3,11-dien-6-α-ol (9.6%), while the chemical composition of A. montana oil was characterized by a high content of fatty acids with n-hexadecanoic acid (16.1%) as the main constituent. Antioxidant activity was tested using four different methods, DPPH, ABTS, Reducing power, and Phosphomolybdenum assay. The highest antioxidant activity had essential oil of A. montana using DPPH and Phosphomolibdenum assay, A. millefolium in ABTS method, while A. absinthium oil showed the best ability to reduce Fe ions.
3D hierarchical Co3O4@Co3S4 nanoarrays as cathode materials for asymmetric pseudocapacitors

Three-dimensional (3D) hierarchical Co3O4@Co3S4 nanoarrays (NAs) were synthesized via a stepwise hydrothermal method involving precipitation and in situ sulfurization of Co3O4 nanoneedle arrays (NNAs). By controlling both anion exchange and Ostwald ripening reactions during the sulfurization process, 3D hierarchical Co3O4@Co3S4 NAs with tailored Co3S4 nanostructures have been fabricated as electrode materials for electrochemical capacitor applications. Owing to an interconnected matrix within the 3D architecture, the as-prepared Co3O4@Co3S4 NAs exhibit excellent electrical conductivity, high specific capacity and high cycling stability. It can deliver a high capacitance of 1284.3 F g−1 at 2 mV s−1 and maintain a capacitance retention of 93.1% after 5000 cycles. Moreover, a flexible solid-state asymmetric supercapacitor (ASC) composed of Co3O4@Co3S4 NAs as the positive electrode and activated carbon (AC) as the negative electrode exhibited an energy density of 1.5 mW h cm−3 and a power density of 6.1 W cm−3 at a high operating voltage of 1.6 V. Our results not only present the 3D hierarchical nanostructure of Co3O4@Co3S4 NAs, but they also demonstrate the potential of electrodes for future generation supercapacitors.
RNA structural remodeling by RNA annealer proteins and RNA chaperones

Wie alle anderen biologischen Makromolekule nimmt RNS spezifische dreidimensionale Strukturen an, um seine Aufgaben innerhalb der Zelle zu erfullen. Gleichwohl ist strukturelle Flexibilitat unumganglich fur viele RNS-Molekule, die in mehr als einer funktionellen Konformation vorliegen und sich an Umwelteinflusse anpassen mussen. Desweiteren tragt die Umorganisation von falsch gefalteten Strukturen zur okonomischen Nutzung von bereits synthetisierten Nukleinsauren bei. Die Faltung genau wie die Destabilisierung von Sekundar- und Tertiarstrukturen der RNS wird von verschiedenen externen Faktoren wie Ionen, kleinen positiv geladenen Molekulen und spezifisch oder unspezifisch bindenden Proteinen unterstutzt. In dieser Arbeit werden die molekularen Mechanismen beider Aktivitaten mithilfe der unspezifisch bindenden Peptide HIV-1 Tat(44-61) und E. coli CTD-StpA detailliert untersucht. Das Tat(44-61)-Peptid beschleunigt das Basenpaaren von komplementaren RNS-Molekulen durch eine Uberfuhrung des RNS-Einzelstranges in eine basenpaar-kompetente Konformation. Auserdem verschiebt es das thermodynamische Gleichgewicht zwischen einzel- und doppelstrangiger RNS in Richtung der doppelstrangigen Form. Im Gegensatz dazu destabilisiert CTD-StpA Doppelstrange, wodurch es Strangaustausch, einen Schlusselprozess von RNS-Umfaltung, ermoglicht. Es wird gezeigt, dass die Energiequelle fur den energetisch unvorteilhaften Entfaltungsprozess ein schon fruher postulierter Entropie-Transfer ist. Interessanterweise beschleunigt CTD-StpA ebenfalls das Basenpaaren von RNS-Molekulen. Eine Erklarung fur die Vereinbarkeit dieser scheinbar gegensatzlichen Aktivitaten wird vorgestellt. Auserdem wird die Wichtigkeit der elektrostatischen und transienten Natur der Interaktionen der Peptide mit ihren Substraten herausgearbeitet. Ein generelles Model fur die Beschleunigung des Basenpaarens und Strangaustausch wird vorgeschlagen. Als Abschluss wird eine mogliche biologische Rolle der RNS-Remodellierungsaktivitat des HIV-1 Tat Proteins diskutiert.
A cluster-based approach as an effective way to implement the ECAP (Environmental Compliance Action Program): evidence from some good practices

SMEs can have a considerable impact on the environment. This is not necessarily through individual pressure, but through their combined total impact across environmental sectors. Most SMEs are ‘vulnerably compliant’, especially due to lack of awareness concering the environmental impacts of their own activities, ignorance of environmental legislation, lack of capacity to tackle their environmental impacts. Within this framework, the networking approach known as the “cluster approach” and, especially, its key-instrument: the Environmental Management System, have shown their ability to strengthen the environmental competence and know-how at the local level, as well as the improvement of environmental performances of both individual SMEs and entire productive areas, considered as a whole. The paper aims at presenting the key methodological and operational issues emerging from local experiences, describing them as good practices, and to explain how the “cluster approach” has been further enhanced by way of a EU-funded LIFE project, currently in progress.
Optimisation of photon detector tynode membranes using electron-matter scattering simulations

The object of this thesis work was to develop a (Monte Carlo) simulation package that can be used to aid in the design of the Timed Photon Counter (TiPC). The TiPC is a single photon detector whose working principle is based upon the multiplication of an electron signal by transmission dynodes, or tynodes. For TiPC to be feasible, it is necessary to develop tynodes that have a secondary electron yield of more than 4, preferably with a primary electron energy as low as possible.
Synergetic Effect of Pt and Borate on the TiO2-Photocatalyzed Degradation of Phenol in Water

It has been reported that Pt and borate can promote the TiO2-photocatalyzed degradation of phenol in an aerated aqueous suspension, respectively. Herein, we report a synergism between Pt and borate greatly improving the photocatalytic activity of anatase TiO2. The rate of phenol degradation was dependent on Pt loading, borate concentration, and solution pH. A maximum rate of phenol degradation was observed at 0.52 wt % Pt, 3.0 mM Na2B4O7, and initial pH 9.0, respectively. Under such conditions, the rates of phenol degradation, upon the addition of Pt, borate, and Pt plus borate, were increased by 1.34, 0.22, and 4.87 times, respectively. This mutual action of Pt and borate were also observed from the photocatalytic degradation of 4-chlorphenol, and 2,4-dichlrophenol. A separate experiment with the TiO2 and Pt/TiO2 film electrodes showed that borate could mediate the hole oxidation of phenol, but not water. Furthermore, the electrochemical reduction of O2 over TiO2 and Pt/TiO2, upon addition of borate, bec.
Analisi spettrale dell'attività nervosa simpatica muscolare nell'uomo

Recent applications of frequency domain analysis to the variability of muscle sympathetic nerve activity (MSNA) have improved the comprehension of the relationship between cardiovascular oscillations and the autonomic nervous system. It has been observed that spectral analysis of MSNA is characterized by two major oscillatory components at low (LF) and high (HF) frequencies, similar to those detectable in the variability of cardiovascular signals. Pharmacological and non-pharmacological studies have shown that, at least within the physiological range, the two MSNA rhythms show a reciprocal behavior, similar to that already observed for cardiovascular oscillations. The oscillatory pattern of MSNA provides non-redundant but complementary information with respect to the time domain measures of MSNA (burst rate and amplitude) since it has been shown that completely different spectral profiles may be derived from various MSNA recordings. On the other hand, the latter are instead comparable in terms of mass activity. Due to the intrinsic characteristics of the signal, which represents the direct outflow of the central neural structures of the cardiovascular autonomic nervous system, this approach can be considered as a unique window over the central organization of excitatory and inhibitory neural mechanisms responsible for the genesis and the regulation of cardiovascular oscillations.
Risk-managed Collective Pension Schemes with Intergenerational Benefit Smoothing

In view of the repeated severe market downturns since the turn of the century, the interest in risk-based investment strategies has grown in recent years. However, such strategies have not yet made major inroads into the design of pension programs. In this paper, we fill this gap by combining a risk-managed investment strategy with a pension scheme where benefits are smoothed across generations by establishing a collective reserve. We demonstrate that combining the two helps to improve the performance of the pension investments and decreases the risk of a negative reserve in times of a market crisis. We furthermore investigate the implications of imposing varying degrees of diversification across assets in such a scheme.
Shadow Bank and Fintech Mortgage Securitization

Agency MBS issuers can choose among three securitization venues: individual securitization where an issuer uses her own loans to create an MBS, collective securitization where different issuers deliver loans into a common MBS, and cash window where issuers receive immediate cash payment by selling loans to Fannie Mae or Freddie Mac, who then conduct securitization. We find that issuers with greater immediate liquidity needs (e.g., smaller issuers and shadow banks) have a larger fraction of their loans securitized through cash window. The uniform pricing feature of collective securitization results in cross-subsidy from traditional banks, who have relatively high-value loans, to shadow banks, especially fintech issuers, who have relatively low-value loans;hence, shadow banks and traditional banks prefer collective and individual securitization, respectively. We further show that securitization venues affect the quality and quantity of loans that issuers securitize, using Fannie Mae's policy shock on collective securitization and the COVID-19 shock on cash window.
Spillovers from Ancillary Services to Wholesale Power Markets: Implications for Climate Policy

In electricity markets, generators are rewarded both for providing energy and for enabling grid reliability. The two functions are compensated in separate markets: energy markets and ancillary services markets. We provide evidence of changes in the fuel mix in the energy market that is driven by exogenous changes in an ancillary services market. We provide quasi-experimental evidence and a theoretical framework for understanding the mechanism, showing that it results from the multi-product nature of conventional power plants combined with discontinuities in costs. As a result, policy changes relating to grid operations, grid reliability, or climate change could have unintended effects. As an example, our results have particular relevance given the increased deployment of batteries for ancillary services -- we show that such deployment has the potential to increase carbon dioxide emissions in the short term.
Strategic Execution Trajectories

ABSTRACT We obtain the optimal execution strategy for two sequential trades in the presence of a transient price impact. We first present a novel and general solution method for the case of a single trade (a metaorder) that is executed as a sequence of sub-trades (child orders). We then analyze the case of two sequential metaorders, including the case where the size and direction of the second metaorder are uncertain at the time the first metaorder is initiated. We obtain the optimal execution strategy under two different cost functions. First, we minimize the total cost when each metaorder is benchmarked to the price at its initiation, the total separate costs approach widely used by practitioners. Although simple, we show that optimizing total separate costs can lead to a significant understatement of the real costs of trading whilst also adversely impacting order scheduling. We overcome these issues by introducing a new cost function that splits the second metaorder into two parts, one that is predictable when the first metaorder is initiated and a residual that is not. The predictable and residual parts of the second metaorder are benchmarked using the initiation prices of the first and second metaorders, respectively. We prove existence of an optimal execution trajectory for linear instantaneous price impact and positive definite decay, and derive the explicit form of the minimizer in the special case of exponentially decaying impact, however uniqueness in general remains unproven. Various numerical examples are included for illustration.
Optimization and Characterization of Biocompatible Oil-in-Water Nanoemulsion for Pesticide Delivery

The formation of promising oil-in-water nanoemulsion suitable for pesticide delivery has been achieved by using methyl laurate as oil phase, and alkyl polyglycoside (APG) and polyoxyethylene 3-lauryl ether (C12E3) as mixed surfactant. Effects of APG and C12E3 mixing ratios, oil weight fraction, and total surfactant concentration on droplet size and distribution of the nanoemulsion were systematically investigated. Long-term stabilities of the nanoemulsions prepared with various surfactant mixing ratios were assessed by measuring droplet size at different time intervals; the results indicated that the main driving force for droplet size increase over time was Ostwald ripening. On this basis, a practical water-insoluble pesticide β-cypermethrin (β-CP) was incorporated into two optimized nanoemulsion systems to demonstrate potential applications. The results of dynamic light scattering (DLS) and transmission electron microscopy (TEM) measurements showed that the nanoemulsions had a nearly monodisperse drople.
Availability of organic contaminants in lake Ketelmeer sediment. Understanding sorption kinetics and distribution of in-situ contaminants

Modeling the fate of organic micropollutants in aquatic systems requires information about gas/water partitioning at environmental temperatures. In this paper experimental data are presented on Henry's Law constant (H) for seven chlorobenzenes, three PCB-congeners and six PAH-compounds. The studied compounds were 1,2,3-; 1,2,4and 1,3,5-tri-; 1,2,3,4and 1,2,3,5-tetra-; penta-; and hexachlorobenzene; 2,5-di-; 2,4,4'-tri-; and 2,2',5,5'tetrachlorobiphenyl; and the PAH compounds fluoranthene, benzo[b]fluoranthene, benzo[k]fluoranthene, benzo[a]pyrene, benzo[ghi]perylene, and indeno[1,2,3-cd]pyrene. H was measured in a buffer solution using a modified gas-purge technique. Values for this set of PAH compounds have not been determined experimentally before. The temperature dependence of H was measured for the tetra-, penta-, and hexachlorobenzenes and for all PCBs and PAHs over a temperature range of 10 to 55oC. The experimental data and temperature dependence are in good agreement with partitioning theory and available literature data. The observed temperature dependence results in a doubling of H for every 10oC temperature increase.
Comparison of homemade and commercial yoghurt in Van province, Turkey

Fermented dairy products with different consistency and aroma are produced especially through lactic acid fermentation with the use of various starter cultures. Among the fermented dairy products, yoghurt is the most known and consumed dairy product. Yoghurt is similar with milk in point of nutrients, but more resistant than milk (Bonczar et al., 2002). Due to significance in human nutrition, health benefits, unique taste and aroma, yoghurt consumption increase worldwide. Taste and aroma are related to production of volatile and non-volatile acids and carbonyl compounds. Homogenization and starter cultures also play a great role in taste and aroma of the yoghurts (Köse&Ocak, 2014).
Analgesic, Antipyretic And Antiulcerogenic Effects Of Andrographolide

Andrographolide from Andrographis panicultata (30, 100, and 300 mg/kg, oral) has been studied for its analgesic, antipyretic and antiulcerogenic activities. Andrographolide did not show any analgesic activity in hot plate test in mice while it showed significant (P< 0.05) analgesic activity in acetic acid-induced writhing in mice and Randall Selitto's test in rats at 300 mg/kg dose. Andrographolide, (100 and 300 mg/kg, oral) produced significant (P < 0.05) antipyretic effect after 3h of administration in Brewer's yeast-induced pyrexia in rats. Andrographolide also possessed significant (p < 0.05) anti-ulcerogenic activity at 100 and 300 mg/kg doses, aspirin induced ulceration in rats.
Prodrug y-L-Glutamyl-L-Dopa: A Central Effect?

The DA prodrug y-L-glutamyl-L-dopa (gludopa) has a high degree of renal selectivity with 2-step conversion to DA in the kidney. The effects of gludopa, with and without DA-2 receptor blockade, on renal and total noradrenaline (NA) Spillover, were studied in two groups of rabbits. Eight rabbits received gludopa infusion (25 and 100 ,€g/kg/min and 8 received an infusion of gludopa and DA-2 receptor antagonist, YM-09151 (50 pg/kg i.v.). Renal and total NA spillover rates were measured by 3H-NA tracer method before and after gludopa infusion. Brain NA, DA, gludopa and L-dopa content were measured after gludopa infusion in 5 rabbits; control values for tissue catecholamine and drug levels were obtained in 5 untreated rabbits. Gludopa infusion markedly increased kidney DA content (300 fold) and DA excretion (6000 fold) but had little effect on plasma DA. It produced a dose-related fall in mean ( ± SEM) renal NA spillover (21.6 ± 3.7 to 10.6 ± 2.7, 7.2 ± 2.7 ng/min, p < 0.01). Even greater falls were observed in total NA spillover after gludopa (43.1 ± 10.2 to 19.7±3.4, 9.4± 1.8 ng/min, p < 0.01). DA-2 receptor antagonism had no influence on the effects of gludopa on either renal or total NA spillover. Significant amounts of gludopa were detected in the brain after drug infusion (0.28 ± 13 nmol/
Raman- and IR-Active Phonons in CdSe/CdS Core/Shell Nanocrystals in the Presence of Interface Alloying and Strain

Semiconductor core–shell nanocrystals (NCs) have greatly improved luminescent properties including better resistance to photobleaching and ligand exchange. It was suggested that compound alloying at the core/shell interface could play an important role in obtaining bright and stable NCs. Here, we investigate the interface composition and strain evolution in spherical and dot-in-plate CdSe/CdS nanocrystals with shell thickness ranging from 1 to 3 nm, using a combination of Raman and infrared spectroscopy. A slower rate of strain accumulation in the core is observed for dot-in-plate nanocrystals and is linked to the anisotropic shape of the plate-like shell. We resolved the respective contributions of the core, shell, and alloyed interface and observed a drastic change of the shell-related Raman feature with the appearance of the bulk-like optical phonon in the shell thicker than 1 nm. The average composition of the alloy interface is estimated using the frequencies of the alloy modes. Because of the high c.
AGVs Collision and Deadlock Handling Based on Structural Online Control Policy: A Case Study in a Square Topology

Based on the novel structural online control policy (SOCP) deadlock handling method presented in our previous work, we have shown that for a specific group of use cases it is possible to relax the requirements of the method, providing an improvement in its performance. In the present work, a new type of deadlock-free zone was introduced which enabled the method to improve its efficiency for both bidirectional as well as unidirectional and mixed path systems. For bidirectional systems, a beneficial outcome was obtained by approaching the global problem solution using sequentially solved local problems. For unidirectional and mixed systems, on the other hand, this paper introduces a condition that allows verification of the feasibility of performing process reservations in a staged manner. The fulfillment of this condition means that there is a possibility of obtaining higher efficiency of the transportation system. The effectiveness of the proposed approaches has been verified by simulations. Their results were compared with the results of the original method resulting in a significant improvement.
In-Fiber Interferometric-Based Sensors: Overview and Recent Advances

In-fiber interferometric-based sensors are a rapidly growing field, as these sensors exhibit many desirable characteristics compared to their regular fiber-optic counterparts and are being implemented in many promising devices. These sensors have the capability to make extremely accurate measurements on a variety of physical or chemical quantities such as refractive index, temperature, pressure, curvature, concentration, etc. This article is a comprehensive overview of the different types of in-fiber interferometric sensors that presents and discusses recent developments in the field. Basic configurations, a brief approach of the operating principle and recent applications are introduced for each interferometric architecture, making it easy to compare them and select the most appropriate one for the application at hand.