Miracle-dz/UniFAR-FTUs huggingface dataset:
A record of syn-tectonic sedimentation revealed by perched alluvial fan deposits in Valles Marineris, Mars

On Mars, basins formed by tectonic processes are rare and mostly have unconstrained subsidence histories. One method for understanding this record of subsidence is through associated alluvial fans, which are sourced from uplifted areas and accumulate in downthrown basins. The source, morphology, and superposition of fan deposits can be used to reconstruct fault kinematics, the relative timing of accommodation space formation, and, in turn, the influence tectonic processes had on Martian fan formation. Here we use high-resolution orbital data sets to characterize sediment fan deposits associated with syn-tectonic sedimentation in two regions of the Valles Marineris canyons: Coprates Chasma and Juventae Chasma. These deposits comprise sediment fans on the current canyon floor and low-gradient surfaces perched several kilometers above the canyon floor. We interpret the low-gradient surfaces as remnant sediment fan deposits, which originally formed at the former canyon floor and have since been offset due to normal faulting. The preservation of vertically offset generations of sediment fan deposits supports a progressive, basinward migration of fault activity into the original hanging wall or repeat activity along a fault zone. Each episode of faulting was followed by a basinward shift in drainages, which led to fault-scarp degradation and formation of a new generation of fans. Multiple episodes of syn-tectonic sedimentation occurred during the evolution of the basins, with fluvial activity sporadically active. Our results demonstrate, for the first time on Mars, that depositional cyclicity was linked to tectonic deformation, possibly representative of regional processes throughout Valles Marineris.
Foot/Ankle Prostheses Design Approach Based on Scientometric and Patentometric Analyses

There are different alternatives when selecting removable prostheses for below the knee amputated patients. The designs of these prostheses vary according to their different functions. These prostheses designs can be classified into Energy Storing and Return (ESAR), Controlled Energy Storing and Return (CESR), active, and hybrid. This paper aims to identify the state of the art related to the design of these prostheses of which ESAR prostheses are grouped into five types, and active and CESR are categorized into four groups. Regarding patent analysis, 324 were analyzed over the last six years. For scientific communications, a bibliometric analysis was performed using 104 scientific reports from the Web of Science in the same period. The results show a tendency of ESAR prostheses designs for patents (68%) and active prostheses designs for scientific documentation (40%).
Chlorine-bearing species and the 37Cl/35Cl isotope ratio in the coma of comet 67P/Churyumov-Gerasimenko

<p>A full-mission analysis of Cl-bearing species in the coma of comet 67P/Churyumov-Gerasimenko has been conducted using data from the Rosetta ROSINA/DFMS mass spectrometer. This contribution will focus on the challenges encountered to relate DFMS data on Cl-bearing species to the neutral abundances at the comet. </p><p>DFMS was operated in neutral mode, in which electron impact ionizes a fraction of the incoming neutral gas in the ion source. Only ions in a narrow range around a certain commanded mass-over-charge ratio (m/z) pass through the mass analyser at a time and impact on a micro-channel plate (MCP), creating an electron avalanche that is recorded by a Linear Electron Detector Array chip with two rows of 512 pixels each (LEDA A and LEDA B). Data are obtained as Analog-to-Digital Converter (ADC) counts as a function of LEDA pixel number. The instrument scans over a sequence of m/z values. </p><p>A well-defined approach exists to convert ADC counts as a function of pixel number to the number of ions that were detected on the MCP. However, to relate the number of ions detected this way to the abundance of neutrals in the coma gas, the sensitivity for each neutral needs to be known. The sensitivity for a certain neutral takes into account the total ionization cross section for the neutral and product ion fraction, instrument transmission and secondary electron yield for each product ion. Sensitivities can be determined experimentally by introducing the neutrals in the DFMS instrument copy in the laboratory, but such data are not available for Cl-bearing species and an alternative approach needs to be used. Fortunately, the use of ratios cancels out some of the factors that play a role in the sensitivity. As an example, for the <sup>37</sup>Cl/<sup>35</sup>Cl ratio, total ionization cross sections and product ion fractions can be considered identical. In the case of <sup>37</sup>Cl/<sup>35</sup>Cl, taking into account the sensitivity results in a correction of more than 15%, mainly due to the secondary electron yield. </p><p>The<sup> 37</sup>Cl/<sup>35</sup>Cl ratio does not appear to change appreciably throughout the mission and is compared with known values from other solar system objects. The Cl/HCl ratio obtained with DFMS indicates that there must be at least one additional chlorine-bearing species on the comet next to HCl, CH<sub>3</sub>Cl and NH<sub>4</sub>Cl, the identity of which is unknown at this time. </p>
Design of a randomised, double-blind, crossover, placebo-controlled trial of effects of sildenafil on cerebrovascular function in small vessel disease: Oxford haemodynamic adaptation to reduce pulsatility trial (OxHARP)

Background Cerebral small vessel disease (SVD) is associated with increased cerebrovascular pulsatility, endothelial dysfunction, and impaired vascular reactivity. Vasodilating phosphodiesterase inhibitors may improve cardiovascular pulsatility and reactivity, and potentially reduce progression of SVD. Hypothesis: Sildenafil, a PDE5 inhibitor, will reduce cerebrovascular pulsatility and increase cerebrovascular reactivity compared to placebo, and is non-inferior to cilostazol, a PDE3 inhibitor. Methods OxHARP is a randomised, double-blind, crossover trial of sildenafil 50 mg thrice daily, cilostazol 100 mg twice daily and placebo in 75 patients with mild to moderate small vessel disease and a previous lacunar or cryptogenic stroke or TIA. Participants undergo a physiological assessment at baseline and on each treatment, including transcranial Doppler ultrasound (TCD, DWL DopplerBox) to assess cerebrovascular pulsatility and reactivity to 4–6% carbon dioxide. In up to 60 patients, cerebrovascular pulsatility, perfusion and reactivity will also be assessed by MRI. Outcome measures The primary outcome is difference in middle cerebral artery pulsatility (Gosling’s Pulsatility Index, PI) after 3 weeks of sildenafil versus placebo. Secondary outcomes including non-inferiority of sildenafil vs cilostazol in effects on PI, percentage increase in MCA blood flow velocity and BOLD-fMRI response during inhalation of 4–6% carbon dioxide. Discussion Reduction in cerebral pulsatility and increased cerebrovascular reactivity during treatment with sildenafil would indicate potential benefit to prevent progression of SVD, suggesting a need for trials with clinical outcomes. Trial Registration OxHARP is registered with ClinicalTrials.org, NCT03855332
Accelerated Brain Aging in Amnestic Mild Cognitive Impairment: Relationships with Individual Cognitive Decline, Risk Factors for Alzheimer Disease, and Clinical Progression.

Purpose To determine whether a brain age prediction model could quantify individual deviations from a healthy brain-aging trajectory (predicted age difference [PAD]) in patients with amnestic mild cognitive impairment (aMCI) and to determine if PAD was associated with individual cognitive impairment. Materials and Methods In this retrospective study, a machine learning approach was trained to determine brain age based on T1-weighted MRI scans. Two datasets were used for model training and testing-the Beijing Aging Brain Rejuvenation Initiative (BABRI) (616 healthy controls and 80 patients with aMCI, 2010-2018) and the Alzheimer's Disease Neuroimaging Initiative (ADNI) (589 healthy controls and 144 patients with aMCI, 2010-2018). A total of 974 healthy controls were used for model training (490 from BABRI and 484 from ADNI; age range, 49-95 years). The trained model was then tested on both healthy controls (126 from BABRI and 105 from ADNI) and patients with aMCI (80 from BABRI and 144 from ADNI) to estimate PAD (predicted age - actual age). Furthermore, the associations between PAD with cognitive impairment, genetic risk factors and pathologic markers of Alzheimer disease (AD), and clinical progression in patients with aMCI were examined using a partial correlation analysis, a two-way analysis of covariance, and a general linear model, respectively. Results Based on the prediction model, patients with aMCI were found to have higher PADs than those of healthy controls (BABRI: 2.65 ± 4.91 [standard deviation] vs 0.18 ± 4.79 [P < .001]; ADNI: 1.68 ± 5.28 vs 0.05 ± 4.41 [P < .001]). Moreover, the PAD was significantly associated with individual cognitive impairment in several cognitive domains in patients with aMCI (P < .05, corrected). When considering different AD-related risk factors, apolipoprotein E ε4 allele carriers were observed to have higher PADs than noncarriers (3.76 ± 4.82 vs 0.10 ± 5.05; P = .017), and patients with amyloid-positive aMCI were observed to have higher PADs than patients with amyloid-negative status (2.40 ± 5.25 vs 0.93 ± 5.20; P = .003). Finally, PAD combined with other markers of AD at baseline for differentiating between progressive and stable aMCI resulted in an area under the curve value of 0.87. Conclusion The PAD is a sensitive imaging marker related to individual cognitive differences in patients with aMCI.Keywords: MR Imaging, Brain/Brain Stem, Brain Age, Machine Learning, Mild Cognitive Impairment, Structural MRI Supplemental material is available for this article. © RSNA, 2021.
Mapping of Sicilian Pocket Beaches Land Use/Land Cover with Sentinel-2 Imagery: A Case Study of Messina Province

Pocket beaches (PBs) are among the most attractive tourist sites and economic development contributors in coastal areas; however, they are negatively impacted by the combined effects of climate change and anthropogenic activities. Generally, research on PBs is conducted from the beach towards offshore. Studies on the land use/land cover (LULC) of PBs are limited and currently lacking. Such studies deserve more investigation due to the importance of LULC in PBs’ functioning. In this study, supervised classification methods were investigated for LULC mapping of the PBs located in the province of Messina. Sentinel-2B satellite images were analyzed using maximum likelihood (MaL), minimum distance (MiD), mahalanobis distance (MaD) and spectral angle mapper (SAM) classification methods. The study was conducted mainly in order to determine which classification method would be adequate for small scale Sentinel-2 imagery analysis and provide accurate results for the LULC mapping of PBs. In addition, an occurrence-based filter algorithm in conjunction with OpenStreetMap data and Google Earth imagery was used to extract linear features within 500 m of the inland buffer zone of the PBs. The results demonstrate that information on the biophysical parameters, namely surface cover fractions, of the coastal area can be obtained by conducting LULC mapping on Sentinel-2 images.
An analysis of CRM practices in the telecommunication industry in Iraq

Today, concerning the capacityto react straight for wardly to client demands and offer the client a profound experience that is customized and interactive, organizations in the telecommunication industry must have the capacity toset up, support and continue the connections toward long-term clients. This study attempts to analyze and observe the customer relationship management (CRM) practices that affectfirm performance telecommunication corporations. Thus, the study employed a qualitative method, the primary data were obtained using the questionnaire and the respondents consisted of 100 people. The results propose that customer relationships' management factors included the gathering of information, the processing of data, the management of information, the loyalty of customers, and the retention of customers with significantly related to the performance of a firm in the industry of telecommunication in Iraq.
Disturbance is complicated: Headward‐eroding saltmarsh creeks produce multiple responses and recovery trajectories

Disturbances are one of the most important processes affecting natural systems, but there is a gap between simple conceptual models of disturbance and complex empirical studies. We studied the perturbation caused by headward‐eroding creeks in southeastern USA salt marshes. We measured disturbance responses (magnitude and recovery trajectory) of 19 variables. Some variables (shoot density, root biomass, snail density, soil pH, soil strength, soil temperature, elevation) declined sharply, while other variables (crab burrow density, soil organic matter, soil redox) increased sharply, in response to the burrowed and grazed conditions at the creek head. These variables recovered over subsequent years or decades. Other variables (shoot height, aboveground biomass, rhizome biomass, light interception) declined sharply in the creek head, then overshot control values before recovering. Some variables (benthic algae, soil salinity) did not appear to be disturbed by the creek head. As hypothesized, plants recovered before soils and snails. Disturbance magnitude and time to recovery were often greater directly adjacent to the new creekbank than for the same variables in a parallel transect further away from the creekbank, and in some cases variables never converged with control values, indicating a persistent state change. Reducing the dimensionality of the data set into principal component axes obscured the diverse ways in which different aspects of the system responded to and recovered from the perturbation. Our study illustrates the challenges in moving from simple conceptual models of disturbance to empirical studies in which multiple variables are likely to be affected differently and follow different recovery trajectories.
Interpolating missing land cover data using stochastic spatial random forests for improved change detection

Forest cover requires large scale and frequent monitoring as an indicator of biodiversity and progress towards United Nations and World Bank Sustainable Development Goal 15. Measuring change in forest cover over time is an essential task in order to track and preserve quality habitats for species around the world. Due to the prohibitive expense and impracticality of mass field data collection to monitor forest cover at regular intervals, satellite images are a key data source for monitoring forest cover globally. A challenge of working with satellite images is missing data due to clouds. Existing methods for interpolating the missing data based on past images, such as compositing, are effective for stable land cover but can be inaccurate for dynamic and substantially changing landscapes. Here we present an adaptation of our recent stochastic spatial random forest (SS‐RF) method, which combines observed data from a prior image and modelled estimates of the current image to produce interpolated land cover values and associated probabilities of those values. Results show our SS‐RF method accurately detected simulated land cover change under both clear felling (0.83 average overall accuracy) and tree thinning (0.85 average overall accuracy). Our method detected forest cover change substantially more accurately than compositing, offering 39% and 12% increases in average overall accuracy for clear felling and tree thinning simulations respectively. However, when natural fluctuation occurs and there is minimal change in land cover, compositing has equivalent or more accurate performance than our method. Overall we find that our SS‐RF method produces accurate estimates under a range of simulated forest clearing scenarios and has a more accurate and robust performance than compositing when modelling noticeably changing landscapes.
Telerehabilitation assessment domains and process in chronic diseases: a scoping meta-review

Background Telerehabilitation (TR) interventions are receiving increasing attention. They have been evaluated in various scientific areas through systematic reviews. However, there is a lack of data on how to standardize assessment and report on their domains to guide researchers across studies and bring together the best evidence to assess TR for chronic diseases.Aims and Objectives The aim of this study is to identify domains of assessment in TR and to qualitatively and quantitatively analyze how they are examined to gain an overview of assessment in chronic disease and understand the complexity of TR interventions.Methods A scoping meta-review was carried out on 9 databases and gray literature from 2009 to 2019. The keyword search strategy was based on "telerehabilitation", “evaluation", “chronic disease" and their synonyms. All articles were subjected to qualitative analysis using the Health Technology Assessment (HTA) Core Model prior to further analysis and narrative synthesis.Results Among the 7412 identified articles, 80 studies met the inclusion criteria. Regarding the domains of assessment, the most frequently occurring were “social aspect” (n = 63, 79%) (e.g., effects on behavioral changes) and “clinical efficacy” (n = 53, 66%), and the least frequently occurring was “safety aspects” (n= 2, 3%). We also identified the phases of TR in which the assessment was conducted and found that it most commonly occurred in the pilot study and randomized trial phases and least commonly occurred in the design, pretest, and postintervention phases.Conclusions Through the HTA model, this scoping meta-review highlighted the multidisciplinarity and comprehensiveness of TR assessment in the recent literature. Future studies will benefit from approaches that leverage the best evidence regarding the assessment of TR interventions, and it will be interesting to extend this assessment framework to other chronic diseases.
Acquired Brain Injury in Adults: A Review of Pathophysiology, Recovery, and Rehabilitation.

Purpose To summarize existing literature from a range of fields (i.e., neurology, neuropsychology, neuroscience, neuroimaging, rehabilitation, speech-language pathology) that is relevant to the development and/or revision of cognitive rehabilitation programs for individuals with acquired brain injury (ABI) and in particular, for young adults. Method This paper reviews a range of ABI-associated topics including: 1) mechanisms of injury; 2) biological, individual-specific, and behavioral drivers of recovery; and 3) current methods of cognitive rehabilitation. It then narrows focus to young adults, a frequently affected and growing population to sustain ABI. The paper concludes by providing: 1) suggestions for key components of cognitive rehabilitation for young adults with ABI; 2) an example from our own research providing intensive academically-focused cognitive rehabilitation for young adults with ABI pursuing college; and 3) recommendations for future behavioral and neuroimaging studies in this area. Conclusions ABI is on the rise in the United States. Young adults have been sustaining ABI at higher rates over the past several decades. These injuries occur when they would otherwise be advancing their academic and career goals, making the cognitive deficits that often accompany ABI especially devastating for this group. Review of existing literature suggests cognitive rehabilitation programs that combine aspects of restorative, comprehensive, and contextualized approaches could promote recovery for young adults with ABI. Future intervention studies may benefit from including both behavioral and neural outcomes to best understand how principles of neuroplasticity- naturally embedded within many cognitive rehabilitation approaches-could be manipulated to promote cognitive recovery and long-lasting brain reorganization in this group.
Recent advances in the transesterification of β-keto esters

The ability to selectively transesterify β-keto esters is a useful transformation in organic synthesis. The increasing interest in transesterification for the synthesis of compounds of pharmaceutical importance, as well as for biodiesel production, has led to the development of a variety of different approaches. This article aims to summarise recent advances in the transesterifications of β-keto esters. Particular interest has been paid to methodologies with minimal environmental impact.
Capacitive Power Transfer With Series-Parallel Compensation for Step-Up Voltage Output

In this article, a basic capacitive power transfer topology with series-parallel compensation is developed for load-independent step-up voltage output. There are three main contributions. First, the step-up constant-voltage (CV) output and zero-phase angle property are designed by using an h-parameter modeling method. Second, a current-source rectifier is proposed at the secondary side and the working transient is analyzed. Third, the impact of parasitic resistances is investigated, and the output voltage attenuation and system efficiency are analyzed at different loads, coupling coefficients, and quality factors. A 130-W prototype is implemented with 150 × 300-mm metal plates. Experiments validate the CV output property with a step-up voltage gain of 2. The peak efficiency is 86.6% at a coupling coefficient of 0.16 and a transfer distance of 4 mm.
TiO2 Inverse Opals Modified by Ag Nanoparticles: A Synergic Effect of Enhanced Visible-Light Absorption and Efficient Charge Separation for Visible-Light Photocatalysis

This work reports on the synthesis, characterization, and photocatalytic performance of the TiO2 inverse opal nanostructure (IP-TiO2) and the IP-TiO2 modified by Ag nanoparticles (Ag@IP-TiO2). The IP-TiO2 is fabricated using polystyrene spheres as the template and TiCl4 as the precursor, and the Ag@IP-TiO2 is realized by photoreduction method. The morphological, structural, and optical properties of the materials are investigated by scanning electron microscopy, X-ray diffraction, ultraviolet–visible (UV-VIS) absorption spectroscopy, and photoluminescence spectroscopy. Their photocatalytic performances are studied by the degradation of rifampicin antibiotic under the visible-light irradiation generated by an LED lamp. The results demonstrate that the IP-TiO2 is composed of mesopores arranged in the honeycomb structure and strongly absorbs visible light in the wavelength range of 400–500 nm. This facilitates the visible-light catalytic activity of IP-TiO2, which is further enhanced by the surface modification by Ag nanoparticles. Our studies on the UV-VIS absorption and photoluminescent properties of the materials reveal that the presence of Ag nanoparticles not only enhances the visible-light absorption of IP-TiO2, but also reduces the recombination of photogenerated electrons and holes. These two factors create a synergic effect that causes the enhanced photocatalytic performance of Ag@IP-TiO2.