Miracle-dz/UniFAR-FTUs huggingface dataset:
casei group show diverse abilities for the production of flavor compounds in 2 model systems

Cheese flavor development is directly connected to the metabolic activity of microorganisms used during its manufacture, and the selection of metabolically diverse strains represents a potential tool for the production of cheese with novel and distinct flavor characteristics. Strains of Lactobacillus have been proven to promote the development of important cheese flavor compounds. As cheese production and ripening are long-lasting and expensive, model systems have been developed with the purpose of rapidly screening lactic acid bacteria for their flavor potential. The biodiversity of 10 strains of the Lactobacillus casei group was evaluated in 2 model systems and their volatile profiles were determined by gas chromatography-mass spectrometry. In model system 1, which represented a mixture of free AA, inoculated cells did not grow. In total, 66 compounds considered as flavor contributors were successfully identified, most of which were aldehydes, acids, and alcohols produced via AA metabolism by selected strains. Three strains (DPC2071, DPC3990, and DPC4206) had the most diverse metabolic capacities in model system 1. In model system 2, which was based on processed cheese curd, inoculated cells increased in numbers over incubation time. A total of 47 compounds were identified, and they originated not only from proteolysis, but also from glycolytic and lipolytic processes. Tested strains produced ketones, acids, and esters. Although strains produced different abundances of volatiles, diversity was less evident in model system 2, and only one strain (DPC4206) was distinguished from the others. Strains identified as the most dissimilar in both of the model systems could be more useful for cheese flavor diversification.
Intraspeci ﬁ c diversity in an ecological engineer functionally trumps interspeci ﬁ c diversity in shaping community structure

• We tested whether intraspeci ﬁ c diversity may functionally exceed species diversity. • We used two bioengineering mussel species, one of which displays genetic lineages. • Associated communities, structural and environmental heterogeneity were evaluated. • Ecosystem-level effects varied more intraspeci ﬁ cally than between species.
Phase modulation using a titanium dioxide strip on lithium niobate

: In this manuscript, we demonstrate the first phase modulator using titanium dioxide as a strip loaded waveguide on thin-film lithium niobate. The amorphous titanium dioxide was fabricated using RF reactive sputtering followed by a dielectric lift-off process. Two gold electrodes were deposited next to the waveguide by using the same process. This process eliminates the need for plasma etching or high-temperature vapor deposition methods, opening the door to fabrication on sensitive material systems. A propagation loss of 0.156 dB/mm and V π of 3.2 V at 1550 nm were experimentally measured and reported.
CBC programmes impact in Northwest Nuts II Region of Bulgaria in the period 2007-2013

The purpose of the paper is to study the impact of the cross-border cooperation programmes in the Northwest Nuts II Region of Bulgaria in the period 2007-2013. The results to be achieved with the study is to assess the effectiveness of EU CBC programmes in one of the most backward EU NUTS II region and to identify the positive and negative effects of various interventions realized with EU funding. In addition, the study evaluates the outputs and results of different types of measures, incl. hard and soft projects and their influence on the local economic and sustainable development as well as their contribution to achieving the objectives of EU cohesion policy in the observed programming period. The conclusion made in the paper is directly related to the cross-border and transnational cooperation with specific focus on particular geographical area. Best practices and challenges are also identified and related to the needs and objectives of the target region in the new programming period 2014-2020.
What did I say? versus

The task used most widely to assess recognition of false belief in self and others is the ‘Smarties’ unexpected contents task. Amongst individuals with and without autism, the Self and Other-person test questions of this task are of an equivalent level of difficulty. However, a potential confound with this task may allow the Self test question to be passed without false belief competence. Three groups of participants (with autism, developmental disability and typical development) undertook a new unexpected contents task which did not suffer from this confound. The main finding was that participants with autism performed significantly less well on the Self test question than the Other-person test question on this new task. Individuals with autism may have greater difficulty representing their own beliefs than the beliefs of other people.
Scholarly Commons @ Baptist Health South Florida Scholarly Commons @ Baptist Health South Florida

Non-compaction cardiomyopathy (NCM) is rare congenital cardiomyopathy characterized on cardiac imaging by a two-layered ventricular wall with prominent trabeculations and intertrabecular recesses. This case highlights a patient in his fifth decade who presented from an outpatient setting for abnormal findings found on a transthoracic echocardiogram for syncopal workup. Cardiac MRI was consistent with non-compaction cardiomyopathy. A loop recorder then inserted, and he was placed on guideline-directed therapy for heart failure with reduced ejection fraction (HFrEF) and discharged with life vest since left ventricular ejection fraction (LVEF) > 35%. There are many areas of controversies in NCM, such as prevalence, diagnostic criteria, clinical features, prognosis, and management strategy. We will discuss the etiology, diagnostic criteria, and management.
CEMENTED BIPOLAR HEMIARTHROPLASTY – AN ANALYSIS OF FUNCTIONAL OUTCOME

Background: The life time risk of sustaining a hip fracture in females is 9% at the age of 50, but this rises to 18% by the age of 90. As life expectancy increases, the hip fracture incidence will continue to rise. The management of displaced femoral neck fractures has been controversial for past few decades. Bipolar hemiarthroplasty is the most commonly done procedure in femoral neck fractures. Objective: Our aim was to assess the functional & radiological outcome of cemented bipolar hemiarthroplasty for fracture neck of femur in elderly. Materials and Methods: It is a prospective study of 24 months duration done from March 2019 to March 2021 at SMMCH & RI, Chennai. Using statistical analysis sample size was calculated as 30 patients with neck femur fractures treated with cemented bipolar hemiarthroplasty. Data was collected from hospital records of the patients being admitted and operated and was analysed using SPSS software system. Results: Ninety percent had mild pain. None of the patients had any limp. 66.66% could walk without any support. 43.33% could walk a distance of 6 blocks. 30% could climb stairs without any support and 50% with support. 83.33% had good range of motion. Average Harris Hip Score was 85.76. There were no significant radiological abnormalities. Conclusion: Cemented Bipolar hemiarthroplasty is an ideal procedure for neck of femur fracture as it provides good relief of pain, early mobilization, and excellent range of motion and good level of activities with minimal complications.
GP-confirmed complete Achilles tendon rupture using pocket-sized ultrasound: a case report

The patient was advised to elevate the foot and wait 2 weeks for improvement. Two days later a second GP, who was aware of a history of an audible snap, considered complete tendon rupture and reexamined the patient. Findings included an absent right heel raise due to weakness, minimal active plantar flexion against gravity and lying prone, significant right ankle swelling without bruising, and an altered angle of declination. Palpation elicited no ankle bony tenderness, yet a painful gap was identified 6 cm proximal from the calcaneal attachment, along the line of the Achilles tendon. Simmonds–Thompson’s test was clearly positive. The positive Simmond’s triad indicated a clinical diagnosis of complete rupture of the Achilles tendon. A 3.4
Biomimetic broadband antireflection gratings on Biomimetic broadband antireflection gratings on solar-grade multicrystalline silicon wafers solar-grade multicrystalline silicon wafers

We report a simple and scalable bottom-up technique for fabricating broadband antireﬂection gratings on solar-grade multicrystalline silicon (mc-Si) wafers. A Langmuir-Blodgett process is developed to assemble close-packed silica microspheres on rough mc-Si substrates. Subwavelength moth-eye pillars can then be patterned on mc-Si by using the silica microspheres as structural template. Hemispherical reﬂectance measurements show that the resulting mc-Si gratings exhibit near zero reﬂection for a wide range of wavelengths. Both experimental results and theoretical prediction using a rigorous coupled-wave analysis model show that close-packed moth-eye arrays exhibit better antireﬂection performance than non-close-packed arrays due to a smoother refractive index gradient. V C 2011 American Institute of Physics . [doi:10.1063/1.3660263] Solar cells (
Investor protection Retail AIFs – heterogeneity across the EU

This article provides an overview of the EU market for Alternative Investment Funds (AIFs) sold to retail investors. It presents the first EU-wide analysis of the structure of the retail AIF market, drawing from data collected as the result of the reporting obligation set out in the Directive on Alternative Investment Fund Managers (AIFMD). Overall, the size of AIFs sold to retail investors accounted for 18% of the AIF market in terms of net asset value (NAV) in 2017. Potential risks related to liquidity transformation and liquidity mismatch are analysed. 2017 data suggest no significant signs of liquidity mismatch for AIFs held exclusively by retail clients. The article also describes the heterogeneity across the EU regarding the distribution of retail AIFs which falls under national law
Multiple Time Scales Characteristic of Precipitation in Recent 50 Years of Upper and Middle Reach of Yellow River

Based on the yearly and monthly precipitation data of 45 stations from 1961 to 2011 over the up- per and middle reach of Yellow River (UMRYR), by the method of climate tendency rate, precipita- tion index, concentration degree and period, the precipitation interannual variation and distribu- tion characteristic and its evolution trend were analyzed. The results show that: 1) The annual precipitation rapidly declines from southeast to northwest, and there was a rain shadow area from Lanzhou to Huining of middle Gansu province. The two climate change sensitive areas were source area of the Yellow River and middle and east of Gansu loess plateau. The precipitation in- creased in source area of the Yellow River, mean value of climate tendency rate was 9.5 mm/10a. The drought trend was obvious in middle and east of Gansu loess plateau, average value of climate tendency rate was −23.4 mm/10a. 2) There were significant difference of mobile trend and track of 400 mm rainfall contour between source area and middle reach of the Yellow River. In source area of the Yellow River, the trend of 400 mm rainfall contour moved north, but in middle reach of the Yellow River the contour obvious moved southeast before 2000, and regressed to northwest after 2000. 3) The general variation trend of seasonal distribution of precipitation in UMRYR were that the precipitation reduced obviously in spring and summer but increased significantly in au- tumn, especially after 2000. The variation trend of precipitation in each season was inconsistent in different areas, and the area where seasonal distribution of precipitation was obvious was Gu- anzhong plain. 4) The precipitation concentration period of UMRYR was in July, but concentration period of source area was slightly earlier than middle reach of the Yellow River. The precipitation concentration degree increased from southeast to northwest, and the value was between 0.45 - 0.71. * 通讯作者。
Surgical Management of Irreparable Massive Rotator Cuff Tears – Current Concepts

The treatment of irreparable massive rotator cuff tear is a challenge for shoulder surgeons due to myriad of options presently available. The conservative methods are usually associated with suboptimal outcomes. The present review aims to discuss the current evidence for treating irreparable massive rotator cuff tears and propose an algorithm for the decision making. Keywords: Irreparable, massive, rotator cuff tears, tendon transfer, superior capsular reconstruction
The Aquila Digital Community The Aquila Digital Community

Staphylococcus aureus is an important human pathogen that can infect almost every organ system, resulting in a high incidence of morbidity and mortality. The msaABCR operon is an important regulator of several staphylococcal phenotypes, including biofilm development, cell wall crosslinking, antibiotic resistance, oxidative stress
Effects of plant extracts on selected haematological parameters, digestive enzymes, and growth performance of striped catfish, Pangasianodon hypophthalmus (Sauvage, 1878) fingerlings

This study examined the effects of dietary supplementation with selected plant extracts on the haematology, enzymatic activities, and growth of Pangasianodon hypophthalmus fingerlings. A 60-day feeding trial was conducted with 11 diets: basal diet (basal diet); and basal diet supplemented with 0.4% or 2% Euphorbia hirta (Eh), 0.2% or 1% Phyllanthus amarus (Pa), 0.4% or 2% Mimosa pudica (Mp), 0.2% or 1% Psidium guajava (Pg), and 0.4% or 2% Azadirachta indica (Ai). On days 30 and 60, the haematocrit improved significantly in response to the Pg 0.2 diet (35.9±0.8% and 36.4±0.7%, respectively), while the haemoglobin level increased significantly in fish fed a diet with Mp or Pg at both concentrations. Chymotrypsin activity was highest (121±6.10 U min -1 mg -1 protein) under the Pa 0.2 diet followed by the Eh 0.4 and Pa 1.0 diets (94.1±7.20 and 92.2±7.80 U min -1 mg -1 protein, respectively) on day 30. The Pa 0.2 diet significantly enhanced chymotrypsin activity on day 60 compared to the other diets. Fish fed the Pa 0.2, Pa 1.0, or Pg 1.0 diet showed significantly increased pepsin activity than those fed the control diet on day 30, whereas there was not observed significant difference on day 60. Amylase activity was significantly enhanced in response to the Eh 0.4, Pa 0.2, Pg 0.2, and Ai 0.4 diets, but none of the diets led to a change in trypsin. Sixty days of oral administration of Pg 0.2 or Pa 0.2 extracts modulated haematological parameters and digestive enzyme activities of P. hypophthalmus fingerlings and resulted in higher growth performance.
EFFECT OF BAICALIN ON THE INTESTINAL MICROBIOTA IN OBESE MICE INDUCED BY HIGH-FAT DIET

In order to analyze the effect of baicalin on intestinal microbiota (IM) of obese mice induced by high-fat diet (HFD), four groups of mice, i.e., normal control group, HFD group, baicalin-treated group of normal control, and baicalin-treated group of HFD, were set up. After 12 weeks of treatment, the mice’s body weight, insulin sensitivity, liver histopathological analysis and immunohistochemical analysis were measured. Combining with high-throughput sequencing of IM 16S rRNA gene, the characteristics of obesity induced by HFD and the therapeutic effect of baicalin on obese mice induced by HFD were explored. HFD significantly increased mice body weight, insulin resistance, liver fat accumulation, and the number of macrophages and T cells in the liver, and significantly changed the structure of obese mice IM. Baicalin treatment significantly reduced the weight and insulin resistance of obese mice induced by HFD, liver fat accumulation, and the number of macrophages and T cells, and significantly changed the structure of IM. This study provided reference data for understanding the effect of baicalin on IM composition and metabolism in the treatment of obesity caused by HFD, and helped us to understand the effect of chemicals on IM and its potential
pro-The growth and aflatoxin production of Aspergillus flavus strains on a cheese model system are influenced by physicochemical factors

Traditional cheeses may be contaminated by afla-toxin-producing Aspergillus flavus during the ripening process, which has not been sufficiently taken into account. The objectives of this study were to evaluate the influence of water activity (a w ), pH, and temperature on the lag phases, growth, and aflatoxin production of 3 A. flavus strains (CQ7, CQ8, and CG103) on a cheese-based medium. The results showed that the behavior of A. flavus strains was influenced by pH, a w , and temperature conditions. The CQ7 strain showed the maximum growth at pH 5.5, 0.99 a w , and 25°C, whereas for CQ8 and CQ103 strains, no differences were obtained at pH 5.5 and 6.0. In general, low pH, a w , and temperature values increased the latency times and decreased the growth rate and colony diameter, although a w and temperature were the most limiting factors. Maximum aflatoxin production on the cheese-based medium occurred at pH 5.0, 0.95 a w , and 25 or 30°C, depending on the strain. This study shows the effect of pH, a w , and temperature factors on growth and aflatoxin production of 3 aflatoxigenic A. flavus strains on a cheese-based medium. The findings may help to design control strategies during the cheesemak-ing process and storage, to prevent and avoid aflatoxin contamination by aflatoxigenic molds.
Value, Access, and Use of Ethnobotanical Databases in Ethnopharmacology: Methods, Ethical Research, and a Case Study on the Aurukun Ethnobiology Database Project

Traditional knowledge databases are becoming increasingly instrumental to research objectives in ethnopharmacology. Codified medicinal knowledge of Indigenous peoples is part of what constitutes these databases. Indigenous peoples' medicinal knowledge is systematized in database in order to facilitate analyses by researchers. The value, access, and use of traditional knowledge databases by Indigenous peoples is not well researched. The Aurukun Ethnobiology Database study stands as one example where Aboriginal people have co-developed a database with ethnoscientists using a participatory research process that privileges Indigenous methodologies. The adherence to cultural protocols and control of the database by the community resulted in recommendations from ethnoscience researchers that discourages such projects in the future. Standard methodologies in ethnopharmacology are incongruent with the protection, by Indigenous people, of their knowledge systems. Indigenous geographies' scholarship is used in this thesis to examine how technoscience, disciplines, researchers, and communities interact and how outcomes can work for and/or against equitable research processes, self-determination, and sovereignties' of Indigenous peoples. iv Acknowledgements
IDENTIFICATION OF CAMPYLOBACTER SPP. ISOLATED FROM POWDERED INFANT MILK FORMULA

Campylobacter species are Gram-negative bacilli that are characterized by being catalase-positive, oxidase-positive, motile, microaerophilic bacteria, and non-spore-forming. Campylobacter is often isolated from animal sources, as it inhabits the gastrointestinal tract of both wild and domestic animals and birds, especially poultry. Milk may be possibly contaminated by the direct discharge of a mastitis-affected cow or by excrement from diseased or colonized cattle during milking. Powdered infant formula (PIF) is considered a non-sterile product and may be contaminated intrinsically or extrinsically with various bacteria that can cause critical illness in infants. This study was performed to detect and identify Campylobacter spp. in powdered infant milk formula by phenotypic and genotypic methods. Ten isolates of Campylobacter from eighty-six samples were phenotypically identified and confirmed genotypically by PCR, with a pattern of 11.6%. This Campylobacter could potentially be transmitted to children by PIF consumption that has not been adequately handled, prepared or processed.
Causality between Financial Development and Foreign Direct Investment: Evidence from Tanzania

This study investigates the causal relationship between Foreign Direct Investment (FDI) and Financial Development during the period 1990-2020 in Tanzania. The study aims to shed light on whether FDI inflows have a significant impact on the financial development of the country and vice versa. The analysis employs time series data including GDP, Inflation rate, Formation (capital and Investment), Trade Openness, Country Population size, and Financial Development, to explore the causal links. Using the Granger causality test, the study finds no evidence of causality between FDI and Financial Development, indicating that FDI inflows do not significantly predict changes in financial development, and vice versa. Similarly, the study does not find significant causality between FDI and other control variables such as GDP, Inflation, Formation, and Country Population size. However, there is a significant bi-directional relationship between FDI and Trade Openness, indicating complementarity between FDI and international trade. The results imply that FDI inflows might not be the sole determinant of financial development or other macroeconomic indicators. Policymakers should not solely rely on FDI as a solution to enhance financial development but should focus on creating a conducive environment for FDI and supporting measures that foster financial development independently. The study recommends that policymakers should prioritize strengthening institutions and regulatory frameworks to attract and retain FDI effectively. They should also promote trade liberalization and enhance the domestic financial system to stimulate both FDI inflows and domestic investment.
Quetiapine-Related Deaths: In Search of a Surrogate Endpoint

Quetiapine is a second-generation antipsychotic drug available for two and half decades. Due to increased misuse, prescription outside the approved indications, and availability on the black market, it is being encountered in medicolegal autopsies more frequently. For instance, it has been linked to increased mortality rates, most likely due to its adverse effects on the cardiovascular system. Its pharmacokinetic features and significant postmortem redistribution challenge traditional sampling in forensic toxicology. Therefore, a systematic literature review was performed, inclusive of PubMed, the Web of Science—core collection, and the Scopus databases; articles were screened for the terms “quetiapine”, “death”, and “autopsy” to reevaluate each matrix used as a surrogate endpoint in the forensic toxicology of quetiapine-related deaths. Ultimately, this review considers the results of five studies that were well presented (more than two matrices, data available for all analyses, for instance). The highest quetiapine concentrations were usually measured in the liver tissue. As interpreted by their authors, the results of the considered studies showed a strong correlation between some matrices, but, unfortunately, the studies presented models with poor goodness of fit. The distribution of quetiapine in distinct body compartments/tissues showed no statistically significant relationship with the length of the postmortem interval. Furthermore, this study did not confirm the anecdotal correlation of peripheral blood concentrations with skeletal muscle concentrations. Otherwise, there was no consistency regarding selecting an endpoint for analysis.