Miracle-dz/UniFAR-FTUs huggingface dataset:
The Metabolic and Analytical Changes of Healthy Volunteers upon Intake of Portuguese Extra Virgin Olive Oil: A Comparison Study between Pre- and Post-Intervention

(1) Background: Extra virgin olive oil (EVOO) is studied mostly for its health benefits in preventing non-communicable chronic diseases, particularly within a Mediterranean dietary pattern. However, few studies have addressed the effect of EVOO in healthy individuals, prior to an established disease. This study aims to evaluate the impact of Northern Portuguese polyphenol-rich EVOO (NPPR-EVOO) consumption on various important clinical parameters in healthy adult volunteers. (2) Methods: This quasi-experimental intervention study assessed the impact of NPPR-EVOO for a period of 100 days. Serum total cholesterol, HbA1c, HDL-c, LDL-c, and CRP, and anthropometric measures—waist and hip perimeters, hand grip strength, and body fat—were assessed and food logs were analyzed. (3) Results: Serum HbA1c (5.12 ± 0.32%; 4.93 ± 0.24, p = 0.000) and LDL-c (96.50 ± 28.57 mg/dL; 87.41 ± 31.38 mg/dL, p = 0.017) significantly decreased following NPPR-EVOO. Also, daily energy significantly increased, but no changes in other dietary parameters, or anthropometry, were seen. Adherence to the Mediterranean diet did not explain the differences found in individuals regarding serum lipid profile and HbA1c, reinforcing the role of EVOO’s effect. (4) Conclusions: NPPR-EVOO lowered the serum levels of LDL cholesterol and HbA1c, providing clues on the effect of EVOO-putative health benefits. These results pave the way for a deeper exploration of EVOO as a functional food.
Potential method of nonlinear resistive circuits to solve max-flow/min-cut problems

In this paper, we propose a new potential method of nonlinear resistive circuits to solve the max-flow/min-cut problems. The important point is that simultaneous analysis of the max-flow and the min-cut can be made based on the dynamics of a single state in the circuit. Although the max-flow problem and the min-cut problem are in duality, the respective algorithms are different in conventional methods. In other words, the simultaneous analysis for the max-flow/min-cut problems does not exist. Our proposed method enables the simultaneous analysis only by nonlinear resistive circuit analysis. Additionally, the min-cut can be found from the node voltages directly. The node voltages enable the finding of all min-cuts easily when a graph has multiple min-cuts, which are found when plural cuts with the same min-cut capacity exist in the same graph. In conventional min-cut algorithms, it is hard to obtain multiple min-cuts. Moreover, our proposed method has a huge advantage of being suitable for hardware implementation. When the proposed circuit model is designed with the integrated circuit such as analog type Programmable Logic Device, Memristor or Phase Change Memory which can change graph structure and branch conductance, the novel min-cut solution with real-time processing can be expected.
Fuzzy Systems in Business Valuation

This research aims to develop a model that is able to integrate and objectify information provided by the different business valuation methods, incorporating quality management in its formal approach, which to date has not been considered in the literature about business valuation or quality management. Firstly, the company is valued using the methods which best adapt to its specific characteristics. Because of the subjectivity inherent in any valuation process, the results will be expressed through Triangular Fuzzy Numbers (TFN). These Fuzzy Numbers will be aggregated and summarized by applying Basic Defuzzification Distribution Uncertain Probabilistic Ordered Weighted Averaging operator (BADD-UPOWA). The weighting factors will be: the degree of confidence in each of the business valuation methods applied, and the innovative use of the company’s position on Crosby’s Quality Administration Grid. The results from application of the model in a case study show a significant reduction in uncertainty in contrast to the initial valuations. Moreover, the proposed methodology is seen to increase the final value of the company as its advances in quality management.
3D package-integrated artificial magnetic conductor antenna arrays for 60 GHz transceivers

Abstract We present a low-profile design of dipole antenna arrays integrated on a planar artificial magnetic conductor (AMC) based on spiral unit cells. The whole system is designed and manufactured on a multi-layer organic laminate packaging technology and can be integrated with a single-chip 60-GHz radio transceiver die. We analyze two fabricated arrays of different total area both of which contain 16 elements fed through a combiner network exciting the array elements either in phase or for 45° scan angle. The integrated antenna-AMC array element presented has twice the impedance bandwidth necessary to cover all international 60-GHz radio bands, small form factor suitable for on-package integration, and 5 dBi gain including all losses. The larger 16-element array, occupying 11 × 11 mm2 package area, has a measured gain of 17 dBi at broadside and 15 dBi at 45° scan angle, while the smaller array, occupying a 6.6 × 11 mm2 package area, has a gain of 15 dBi at broadside and 14 dBi at a 45° scan angle. These arrays are an ideal 3D-integrated package solution for 60 GHz radio transceivers.
Free recall: have we been looking at the wrong curve?

I show that without the serial position curve, free recall can appear just as simple as integer recognition. The total search in word free recall, averaged over item position, increases linearly with the number of items recalled. Thus the word free recall search algorithm scales the same as the low-error recognition of integers [13]. The linear scaling of the search algorithm is different from what is commonly assumed to be the word free recall search algorithm, search by random sampling. The proportionality constant of 2-4 seconds per item (a hundred times larger than for integer recognition) is a power function of the average proportion not remembered and seems to be explicitly independent of subject age, presentation rate and whether there is a delay after the list presentation or not. The linearity of the word free recall extends down to 3 items which presents a challenge to the prevalent working memory theory in which 3-5 items are proposed to be stored in a separate high-availability store
Blind Deconvolution Method of Image Deblurring Using Convergence of Variance

Images are used for both aerial and space imagery applications, including target detection and tracking. The current problem concerning objects in geosynchronous orbit is that they are dim and hard to resolve because of their distance. This work will further the combined effort of AFIT and AFRL to provide enhanced space situational awareness (SSA) and space surveillance. SSA is critical in a time when many countries possess the technology to put satellites into orbit. Enhanced imaging technology improves the Air Force’s ability to see if foreign satellites or other space hardware are operating in the vicinity of our own assets at geosynchronous orbit. Image deblurring or denoising is a crucial part of restoring images that have been distorted either by movement during the capture process, using out-of-focus optics, or atmospheric turbulence. The goal of this work is to develop a new blind deconvolution method for imaging objects at geosynchronous orbit. It will feature an expectation maximization (EM) approach to iteratively deblur an image while using the convergence of the image’s variance as the stopping criteria
RNA-Seq Virus Fraction in Lake Baikal and Treated Wastewaters

In this study, we analyzed the transcriptomes of RNA and DNA viruses from the oligotrophic water of Lake Baikal and the effluent from wastewater treatment plants (WWTPs) discharged into the lake from the towns of Severobaikalsk and Slyudyanka located on the lake shores. Given the uniqueness and importance of Lake Baikal, the issues of biodiversity conservation and the monitoring of potential virological hazards to hydrobionts and humans are important. Wastewater treatment plants discharge treated effluent directly into the lake. In this context, the identification and monitoring of allochthonous microorganisms entering the lake play an important role. Using high-throughput sequencing methods, we found that dsDNA-containing viruses of the class Caudoviricetes were the most abundant in all samples, while Leviviricetes (ssRNA(+) viruses) dominated the treated water samples. RNA viruses of the families Nodaviridae, Tombusviridae, Dicitroviridae, Picobirnaviridae, Botourmiaviridae, Marnaviridae, Solemoviridae, and Endornavirida were found in the pelagic zone of three lake basins. Complete or nearly complete genomes of RNA viruses belonging to such families as Dicistroviridae, Marnaviridae, Blumeviridae, Virgaviridae, Solspiviridae, Nodaviridae, and Fiersviridae and the unassigned genus Chimpavirus, as well as unclassified picorna-like viruses, were identified. In general, the data of sanitary/microbiological and genetic analyses showed that WWTPs inadequately purify the discharged water, but, at the same time, we did not observe viruses pathogenic to humans in the pelagic zone of the lake.
A Hierarchical CuO Nanowire@CoFe-Layered Double Hydroxide Nanosheet Array as a High-Efficiency Seawater Oxidation Electrocatalyst

Seawater electrolysis has great potential to generate clean hydrogen energy, but it is a formidable challenge. In this study, we report CoFe-LDH nanosheet uniformly decorated on a CuO nanowire array on Cu foam (CuO@CoFe-LDH/CF) for seawater oxidation. Such CuO@CoFe-LDH/CF exhibits high oxygen evolution reaction electrocatalytic activity, demanding only an overpotential of 336 mV to generate a current density of 100 mA cm−2 in alkaline seawater. Moreover, it can operate continuously for at least 50 h without obvious activity attenuation.
A Study on Differential Biomarkers in the Milk of Holstein Cows with Different Somatic Cells Count Levels

Simple Summary Mastitis is one of the most common diseases in the dairy industry in the world, and its treatment cost is also the most expensive of all diseases in the dairy industry. The research on the rapid diagnosis of cow mastitis is of great significance to the development of the dairy cow industry all over the world. In this study, we use microbiology and metabolomics techniques to explore the differential microbiota and metabolites in cow milk at different somatic levels, to find new biomarkers for the diagnosis of cow mastitis and provide a new plan for the diagnosis, prevention, and treatment of mastitis in the future. Abstract Dairy cow mastitis is one of the common diseases of dairy cows, which will not only endanger the health of dairy cows but also affect the quality of milk. Dairy cow mastitis is an inflammatory reaction caused by pathogenic microorganisms and physical and chemical factors in dairy cow mammary glands. The number of SCC in the milk of dairy cows with different degrees of mastitis will increase in varying degrees. The rapid diagnosis of dairy cow mastitis is of great significance for dairy cow health and farm economy. Based on the results of many studies on the relationship between mastitis and somatic cell count in dairy cows, microflora, and metabolites in the milk of Holstein cows with low somatic cell level (SCC less than 200,000), medium somatic cell level (SCC up to 200,000 but less than 500,000) and high somatic cell level (SCC up to 5000,00) were analyzed by microbiome and metabolic group techniques. The results showed that there were significant differences in milk microbiota and metabolites among the three groups (p < 0.05), and there was a significant correlation between microbiota and metabolites. Meanwhile, in this experiment, 75 differential metabolites were identified in the H group and L group, 40 differential metabolites were identified in the M group and L group, and six differential microorganisms with LDA scores more than four were found in the H group and L group. These differential metabolites and differential microorganisms may become new biomarkers for the diagnosis, prevention, and treatment of cow mastitis in the future.
Spontaneous Water-Promoted Self-Aggregation of a Hydrophilic Gold(I) Complex Due to Ligand Sphere Rearrangement

Aggregating gold(I) complexes in solution through short aurophilic contacts promotes new photoluminescent deactivation pathways (aggregation-induced emission, AIE). The time dependence of spontaneous AIE is seldom studied. We examine the behavior of complex [Au(N9-hypoxanthinate)(PTA)] (1) in an aqueous solution with the aid of variable-temperature NMR, time-resolved UV–Vis and photoluminescence spectroscopy, and PGSE NMR. The studies suggest that partial ligand scrambling in favor of the ionic [Au(PTA)2][Au(N9-hypoxanthinate)2] pair followed by anion oligomerization takes place. The results are rationalized with the aid of computational calculations at the TD-DFT level of theory and IRI analysis of the electron density.
Contribution of the Nuclear Localization Sequences of Influenza A Nucleoprotein to the Nuclear Import of the Influenza Genome in Infected Cells

Replication of the RNA genome of influenza A virus occurs in the nucleus of infected cells. The influenza nucleoprotein (NP) associated with the viral RNA into ribonucleoprotein complexes (vRNPs) is involved in the nuclear import of the viral genome. NP has two nuclear localization sequences (NLSs), NLS1 and NLS2. Most studies have concentrated on the role of NP’s NLSs using in vitro-assembled or purified vRNPs, which may differ from incoming vRNPs released in the cytoplasm during an infection. Here, we study the contribution of the NP’s NLSs to the nuclear import of vRNPs in a cell culture model system for influenza infection: human lung carcinoma cells infected with viruses containing NP-carrying mutations in NLS1 or NLS2 (NLS2MT), generated by reverse genetics. We found that cells infected with these mutant viruses were defective in the nuclear import of incoming vRNPs and produced reduced amounts of newly synthesized NP, newly assembled vRNP, and progeny virus. In addition, NLS2MT-infected cells were also defective in the nucleolar accumulation of NP, confirming the nucleolar localization role of NLS2. Our findings indicate that both NLS1 and NLS2 have to be present for successful infection and demonstrate the crucial role of these two NLSs in the infection cycle of the influenza A virus.
High-Performance Au@Ag Nanorods Substrate for SERS Detection of Malachite Green in Aquatic Products

In order to improve the detection performance of surface-enhanced Raman scattering (SERS), a low-cost Au@Ag nanorods (Au@Ag NRs) substrate with a good SERS enhancement effect was developed and applied to the detection of malachite green (MG) in aquaculture water and crayfish. By comparing the SERS signal enhancement effect of five kinds of Au@Ag NRs substrates with different silver layer thickness on 4-mercaptobenzoic acid (4-MBA) solution, it was found that the substrate prepared with 100 µL AgNO3 had the smallest aspect ratio (3.27) and the thickest Ag layer (4.1 nm). However, it showed a good signal enhancement effect, and achieved a detection of 4-MBA as low as 1 × 10−11 M, which was 8.7 times higher than that of the AuNRs substrate. In addition, the Au@Ag NRs substrate developed in this study was used for SRES detection of MG in crayfish; its detection limit was 1.58 × 10−9 M. The developed Au@Ag NRs sensor had the advantages of stable SERS signal, uniform size and low cost, which provided a new tool for SERS signal enhancement and highly sensitive SERS detection method development.
Parameter space based robust control methods

The parameter space approach to robust control is presented in this paper as a pre-requisite to the remaining book chapters. The well-established method of mapping the left-half plane for Hurwitz stability or a smaller bounded subregion of the left-half plane for D-stability are presented first. Mapping of phase and gain margin bounds and different sensitivity bounds to parameter space are introduced later in the paper with illustrative examples.
Modélisation d'une chambre réverbérante basée sur la théorie des image: étude en régime pulsé

Dans cet article, nous proposons un modele de chambre reverberante (CR) temporel base sur la theorie des images (TI). Ce modele tres simple permet de simuler le comportement d'une chambre reverberante en presence de signaux pulses. Apres une breve presentation du modele, des resultats de simulations avec des impulsions de durees variables et differentes charges sont comparees a des mesures realisees dans la CR de notre laboratoire.
Vortex light beams in a degenerate two-crystal cascade conical refraction

The transformation of circularly polarized Laguerre–Gauss optical vortex beams with topological charge ℓ = 1 focused through a cascade of two identical biaxial crystals along their optical axes is considered. For such an arrangement, the effect of degenerate conical refraction (CR) produces in the focal image plane a light pattern consisting of a central component and a ring. The relative integral intensity of these two components depends on the rotation angle between the crystals about the beam axis. It is shown that the central component, which appears due to the reversed CR in a degenerate two-crystal arrangement, is a composite vortex consisting of two superimposed vortices identical to the input beam. A single vortex can be selected from this superposition by a polarization control of light components entering the second crystal in the cascade. Such a polarization control also allows the formation of a central vortex possessing ℓ = 3 , or can inverse the input vortex charge ℓ = 1 to ℓ = − 1 . The ring, which appears due to the additive action of two crystals, consists of two interfering components with different vorticity and opposite circular polarizations. For these two components, the vortex charge differs by one and varies from ℓ = − 1 to ℓ = 3 depending on the polarization and vorticity of the light entering the second crystal. A numerical study of cascaded CR with vortex beams has been carried out; the numerical simulation results obtained are in a good agreement with experimental observations.
Canonical finite element method for solving nonconvex variational problems to post buckling beam problem

The goal of this paper is to solve the post buckling phenomena of a large deformed elastic beam by a canonical dual mixed finite element method (CD-FEM). The total potential energy of this beam is a nonconvex functional which can be used to model both pre-and post-buckling problems. Different types of dual stress interpolations are used in order to verify the triality theory. Applications are illustrated with different boundary conditions and external loads by using semi-definite programming (SDP) algorithm. The results show that the global minimum of the total potential energy is stable buckled configuration, the local maximum solution leads to the unbuckled state, and both of these two solutions are numerically stable. While the local minimum is unstable buckled configuration and very sensitive to both stress interpolations and the external loads.
The optimal oxytocin infusion rate for preventing uterine atony during cesarean delivery in elderly parturients with prior history of cesarean delivery

Background: An estimate of 90% effective dose (ED90) of oxytocin infusion has already been proved effective in non-laboring parturients. However, the requirements of oxytocin for elderly parturients with prior history of cesarean delivery (CD) may be higher. The aim of this study was to find the optimum oxytocin infusion rate for preventing uterine atony during CD in elderly parturients with prior history of CD. Method: We performed a randomized, double-blinded study in 120 healthy elderly parturients with prior history of CD scheduled for elective CD under combined spinal–epidural (CSE) anesthesia. Participants were treated with oxytocin infusion randomly at the rates of 0, 4, 8, 12, 16, or 20 IU h−1 after the delivery of infants. Following oxytocin administration, a blinded obstetrician evaluated the uterine tone (UT), verbally describing it using numerical scales (0–10: 0, no UT; 10, optimal UT) as either adequate or inadequate at the time intervals of 3, 6, and 9 min. Maternal adverse effects, requirements for additional uterotonic agents, delivery–placenta delivery time (PD), and estimated blood loss (EBL) were recorded. Results: The 50% effective dose (ED50) and 90% effective dose (ED90) of oxytocin infusion were 14.6 IU h−1 (95% confidence interval 12.0–18.4 IU h−1) and 27.7 IU h−1 (95% confidence interval 22.5–39.4 IU h−1), respectively. As the rate of infusion was increased in parturients, the rescue oxytocin dose and delivery-PD time were decreased. Parturients who received 0 IU h−1 oxytocin at 3, 6, and 9 min obtained lower UT scores than those who received 16 and 20 IU h−1 oxytocin (p < 0.05, respectively). No significant differences were observed among groups in EBL and maternal adverse effects. Conclusion: The infusion rate of oxytocin at 14.57 and 27.74 IU h−1 produces adequate UT in 50% and 90% of elderly parturients with prior history of CD, respectively. An oxytocin infusion rate of 27.7 IU h−1 is suggested to be the optimal dose for preventing uterine atony during CD in elderly parturients with prior history of cesarean delivery. Clinical Trial Registration: [https://www.chictr. org.cn/bin/project/edit? pid=62489], Identifier: [ChiCTR2000038891].
Outcomes at 10-Year Follow-Up after Roux-en-Y Gastric Bypass, Biliopancreatic Diversion, and Sleeve Gastrectomy

Introduction: Morbid obesity is a well-defined chronic disease, the incidence of which is constantly rising. Surgical treatment of morbid obesity has produced superior outcomes compared to conventional weight loss measures. Currently, there is a gap in the literature regarding long-term outcomes. Our single-institution, retrospective cohort study aims to evaluate weight loss outcomes, comorbidity reduction, and adverse effects at 10 years following Roux-en-Y Gastric Bypass (RYGB), Biliopancreatic Diversion (BPD), and Sleeve Gastrectomy (SG). Materials and Methods: We included all consecutive patients with 10-year follow-up records operated on within our institution. The comparison was carried out on the average percentage of weight and BMI loss. Nausea and vomiting were evaluated through self-reporting Likert scales. Diabetes resolution and nutritional deficiencies were also evaluated. Results: A total of 490 patients from 1995 up to 2011 were included in our study. Of these, 322 underwent RYGB, 58 underwent long-limb BPD, 34 underwent laparoscopic RYGB with fundus excision, 47 underwent laparoscopic SG, and 29 underwent laparoscopic RYGB as a revision of prior SG. RYGB and BPD were significantly associated with higher percentages of weight loss (37.6% and 37.5%), but were not found to be independent predictors of weight loss. Nausea and vomiting were associated with SG and laparoscopic RYGB with fundus excision, more so than the other operations. No differences were observed regarding diabetes resolution and nutritional deficiencies. Conclusions: Longer follow-up reports are important for the comparison of outcomes between different types of bariatric operations. BPD and RYGB resulted in superior weight loss, with no observed differences in diabetes resolution and adverse outcomes.