Miracle-dz/UniFAR-FTUs huggingface dataset:
Simulation of Lumbar Spinal Stenosis Using the Finite Element Method

: Lumbar spine stenosis (LSS) is a narrowing of the spinal canal that results in pressure on the spinal nerves. This orthopedic disorder can cause severe pain and dysfunction. LSS is a common disabling problem amongst elderly people. In this paper, we developed a finite element model (FEM) to study the forces and the von Mises stress acting on the spine when people bend down. An artificial lumbar spine (L3) was generated from CT data by using the FEM, which is a powerful tool to study biomechanics. The proposed model is able to predict the effect of forces which apply to the lumbar spine. In addition, FEM allows us to investigate the tests into the lumbar spine instead of applying the tests to the real spine in humans. The proposed model is highly accurate and provides precise information about the lumbar spine (L3). We investigate the behavior of humans in daily life which effects to the lumbar spine in a normal person and a patient with LSS. The computational results revealed high displacement levels around the spinal canal and lower displacement levels in the spinal body when bending down. The total displacement of the axial load in a normal person was higher when compared with patients with LSS. Higher degree bends resulted in a lower total displacement when compared with lower degree bends, while the von Mises stress decreased as the bending degree increased.
Role of molecular and metabolic defects in impaired performance of dystrophic skeletal muscles

There occurs a progressive weakness and wastage of skeletal muscle in different types of muscular dystrophy. The loss of muscle fibers in dystrophic muscle with impaired function is associated with leakage of intracellular enzymes, maldistribution of electrolyte content and metabolic defects in myocytes. Marked increases in the sarcolemma (SL) Na-K ATPase and Ca/Mg-ecto ATPase activities, as well as depressions in the sarcoplasmic reticulum (SR) Ca-uptake and Ca-pump ATPase activities were seen in dystrophic muscles of a hamster model of myopathy. In addition, impaired mitochondrial oxidative phosphorylation and decrease in the high energy stores as a consequence of mitochondrial Ca-overload were observed in these myopathic hamsters. In some forms of muscular dystrophy, it has been shown that deficiency of dystrophin produces marked alterations in the SL permeability and promotes the occurrence of intracellular Ca-overload for inducing metabolic defects, activation of proteases and contractile abnormalities in dystrophic muscle. Increases in SR Ca-release channels, SL Na-Ca exchanger and SL store-operated Ca-channels have been reported to induce Cahandling abnormalities in a mouse model of muscular dystrophy. Furthermore, alterations in lipid metabolism and development of oxidative stress have been suggested as mechanisms for subcellular remodeling and cellular damage in dystrophic muscle. Although, several therapeutic interventions including gene therapy are available, these treatments neither fully prevent the course of development of muscular disorder nor fully improve the function of dystrophic muscle. Thus, extensive reasearch work with some novel inhibitors of oxidative stress, SL Ca-entry systems such as store-operated Ca-channels, Na-Ca exchanger and Ca/Mg-ecto ATPase (Ca-gating mechanism), as well as SR Ca-release and Capump systems needs to be carried out in combination of gene therapy for improved beneficial effects in muscular dystrophy.
Chaos Engineering (Principles of Chaos Engineering) As the Pathway to Excellence and
Relevance in Engineering Education in Africa

A study on engineering in sub-Saharan Africa revealed that engineering is pivotal for economic and social development of any country. This is profound as it underscores the potentials embedded in engineering education for excellence and relevance in Africa. This has not been the case in Africa, as the region has not developed evenly with other countries from the Global South. Hence, the impetus for chaos engineering as a panacea to excellence and relevance in engineering education in Africa. Chaos engineering has been defined by various authors and one of the profound definitions is that chaos engineering is the discipline of experimenting on a distributed system with the intent to build confidence in the system`s capability to withstand turbulent conditions during production. This study therefore looked at chaos engineering, its history and applicability and conceptualize it as a pathway for excellence and relevance in engineering education in Africa. Findings from the that engineering is pivotal for economic and social development of any country but it has not resulted to such in Africa which necessitates chaos principles. It was found out that experimentation is a basic principle of chaos engineering while the advanced principles are hypothesizing about steady state, vary real-world events, run experiments in production, automate experiments to run continuously, minimize blast radius. These all were conceptualized as the pathway to excellence and relevance in engineering education in Africa. The study recommended that there is a need to intensify effort on researching more into chaos engineering in Africa.
The Readiness of Private Vocational School Students in Pringsewu Regency in Learning Local History Teaching Materials KH Gholib's Struggle

By utilizing the development of technology and communication in the 21st century, it is hoped that it can meet the needs of students related to local-based history learning. With the current development of technology and communication, we have felt the impact such as the emergence of various applications with features that can be used to compile and shape teaching materials with digital displays, such as products that have been compiled with the theme KH. Ghalib's struggle. The application used is Flip PDF Professional 2.4. 9.18. By utilizing this technology, it is hoped that it can improve students' readiness to study history, especially those based locally. The methodology used in this research is descriptive qualitative. This method is carried out by distributing questionnaires containing questions about the readiness of Pringsewu Private Vocational School students. The findings in two private schools in Pringsewu Regency, namely SMK Nurul Huda and SMK KH Ghalib, show the readiness of students in learning local history teaching materials. Based on the results of the study, it can be concluded that by utilizing technological and communication advances it can trigger student readiness to learn, especially local-based history learning.
Education Of Life Proficiency In History Learning

The twenty-first century continues to experience a breakdown in the foundations of society which causes new and worrisome things. The emergence of a pandemic in this century has a consequence that has caused various problems, especially in the field of education. The development of community needs for education services, especially at the senior high school level (SMA) is not following the improvement of the quality of human resources with life skills. This happens because educational services have not been able to carry out face-to-face learning completely. The implementation of distance learning (PJJ), the use of online learning technology, re-orientation of the curriculum, and improving the skills of educators are policies that are taken to overcome these problems. This study uses a literature review method that aims to critically examine ideas, findings, and knowledge of life skills education to analyze and solve educational problems during the Pademi era, especially in history learning.
A Proof-of-Transactions Blockchain Consensus Protocol for Large-Scale IoT

Blockchain technology can benefit Internet of Things (IoT) in terms of message exchange, access control, and management; however, existing blockchain consensus protocols cannot provide sufficient performance without compromising security and fairness. This article proposes a round-based two-stage blockchain consensus protocol called Proof-of-Transactions (PoT) for a variety of requirements, such as performance and security of large-scale IoT. In the first stage of each round, all nodes preconstruct new blocks and exchange information about the number of valid transactions contained in each other’s blocks. The block containing most valid transactions is broadcasted in the second stage and examined by all nodes of the cluster before being received as the new block in the global blockchain ledger. The consensus reaching of a new block requires only two rounds of message exchange process. Theoretical analysis and experimental results verify the feasibility and superiority of the proposed protocol.
Problems of the Language in Religion

The purpose of this paper is to describe the problems related to language that arise in religion. Religion in its teachings and dissemination cannot escape from the use of language, especially in every religious scripture that exists. The use and choice of language in religion is also often the cause of the complexity of realizing tolerance in religion. This research uses available literature studies related to language and religion. The author concludes that Language is a key player in a religion in terms of both teaching and teaching.
Re-screening of the Influencing Factors of Advanced Structure of the Manufacturing Industry in the Yangtze River Delta Based on Grey Correlation

In the context of the “Yangtze River Delta Integration Strategy” being upgraded to a national strategy, it is important to examine the influencing factors of advanced structure of the manufacturing industry in the Yangtze River Delta region. This paper intends to select provincial panel data from 2005 to 2018 in the Yangtze River Delta region, screens out 11 influencing factors through literature review, and uses grey correlation and dynamic equation models to analyze the major influencing factors on advanced structure of the manufacturing industry. The results show that: (1) Among the 11 influencing factors, fixed asset investment has the highest correlation with advanced structure of the manufacturing industry, followed by opening up and human capital level. (2) The level of human capital significantly promotes the advanced industrial structure, and the impact of both fixed asset investment and opening up on the advanced structure of the manufacturing industry presents “inverted U-shaped”. According to the research results, it is suggested that the development of manufacturing structure in the Yangtze River Delta must optimize capital investment structure, and obtain high-quality labor force and high-end opening-up.
Design of broadband high-gain GaN MMIC power amplifier based on reactive/resistive matching and feedback technique

This paper presents a K-band two-stage power ampliﬁer (PA) withacompactcircuitsizeof1 . 8 × 0 . 87mm 2 . Toguaranteebroadbandhigh- gain output performance, the optimal impedance domain and power cell are determined through load/source-pull simulation and K-point method, respectively. Reactive/resistive matching networks are carefully employed toreducetheequivalent gatecapacitance, improvestabilityand compensate for the device’s negative gain roll-oﬀ slope. Meanwhile, combining with feedback technique adopted in driver stage, the entire operation bandwidth can be further extended. Under 12V pulse voltage supply, 37.4% of peak power-added eﬃciency (PAE) at 26GHz and 24 ± 0 . 5dB of small-signal gain, 30.3–31.6dBm of saturated output power (P sat ) across 22–27GHz are obtained as shown in the experimental results.
EyePaint: A Gaze Estimation-Based System for Hands-Free Painting

— This paper presents EyePaint, a system that enables hands-free painting on canvas via webcam-based gaze estimation software, a custom graphical user interface (GUI), and a computer numerical control (CNC) modified for painting. The proposed system’s primary use is to assist a user with a physical disability in painting on canvas. Gaze estimation is administered using only a webcam through a unique combination of object detection algorithms, like Haar cascades, to localize facial features and learned linear regression models to translate facial features to gaze location. The custom GUI allows a user to draw a line or a circle in four different paint colors on a virtual canvas before committing their shape to a physical canvas solely through using the low-accuracy webcam-based gaze estimation. The system and its prototype are found to have utility through basic acceptance and system testing, but the chosen gaze estimation solution is generally too low accuracy for a positive user experience.
Synthesis of polycyclic hydrocarbons C14H20 by hydrogenation of exo-exo-, exo-endo-, endo-exo-, and endo-endo- hexacyclo[9.2.1.02,10.03,8.04,6.05,9]tetradec-12-enes with H2SO4 and isomerization of the products to diamantane induced by ionic liquids

A new method was developed for hydrogenation of unsaturated hexacyclic norbornadiene dimers, exo-exo-, exo-endo-, endo-exo-, and endo-endo- hexacyclo[9.2. 1.02,10.03,8.04,6.05,9]tetradec-12-enes, using sulfuric acid (98%), giving pentacyclo[8.2. 1.15,8.02,9.03,7]tetradecanes, which were subjected to skeletal rearrangement under the action of ionic liquids to form diamantane in up to 84% yield.
Scouting Culture and Its Relationship with Scouting Curricula According to the Sustainable Development Goals Perspective among Scout Leaders in Iraq

The development aims to achieve continuous progress in the life and well-being of all residents and is basedon the effective and professional contribution of all individuals to development, and the fair distribution ofits revenues, which requires a scouting leadership that can keep pace with the innovations in society andcan meet the requirements of society focused on preparing a positive citizen who contributes to a solutionHis problems and the problems of his society. The educational institutions in some countries have paidgreat attention to scouting because of its positive effects represented in achieving the advancement andadvancement of societies, in addition to a course in strengthening the sense of citizenship and belongingto members of society, as well as contributing to community participation and development, as Scoutingis one of the pillars of volunteer work. Educators have unanimously agreed on the importance of Scouteducation and its effective role in achieving its goals. Its goal is to build a good citizen by contributing to theeducation and development of youth to achieve the maximum advancement of their physical, mental, socialand spiritual capabilities as good individuals and responsible citizens and members in their local, nationaland global societies, and the research aims to build a scale The reality of the Scout curricula according tothe perspective of the Sustainable Development Goals of Scout leaders in Iraq, and identifying the level ofreality of the Scout curricula according to the perspective of the Sustainable Development Goals amongscout leaders in Iraq.
SLC7A5 Promotes Colorectal Cancer Progression by Regulating Cell Cycle and Migration

Background: Solute carrier family 7 member 5 (SLC7A5) was identified highly expressed and as a key participant in various tumor development; however, the role it played in colorectal cancer remains unclear. Methods and Results: In the current study, the expression of SLC7A5 were systematically mined in public databases and validated by real-time PCR in colon cancer and normal tissues. And then, the co-expression and pathway analysis got from public database, which indicated the potential influence of SLC7A5 for the etiology of colorectal cancer, were evaluated in the colon cancer cell lines by loss of SLC7A5 function experiment, flow cytometry, western blot, and wound healing assay. The results showed that the mRNA expression of SLC7A5 was significantly higher in colorectal cancer tissues than that in the non-tumor controls for GEO and TCGA datasets as well as 40 pairs of Xiangya clinical samples. The functional enrichment analysis based on public database showed that the pathways enriched most were cell cycle and epithelial-to-mesenchymal transition (EMT), and Cyclin D1 (CCND1) were the only gene that had a significant positive correlation with SLC7A5. Loss of SLC7A5 function in colon cancer cell lines could arrest cell cycle at G1 phase by down-regulating CCND1 and CDK2 protein expression, and may reduce cell migration by reversing EMT though upregulation of E-Cadherin and downregulation of zonula occludens-1. Conclusion: SLC7A5 is likely associated with the progression of colon cancer.
Effect of single intravitreal triamcinolone acetonide injection on intraocular pressure and retinal nerve fibre layer thickness

Purpose: To investigate the intraocular pressure (IOP) changes following intravitreal triamcinolone acetonide (IVTA) injection for inflammatory, proliferative and edematous diseases of posterior segment of eye. Design: Prospective longitudinal interventional study. Methods: The prospective longitudinal study included 30 with posterior uveitis (n=12), retinal vascular occlusive diseases (n=10), Eales’ disease (n=6), pseudophakic cystoid macular edema (n=1) and idiopathic cystoid macular edema (n=1). 4 mg of IVTA injection IOP increased significantly from baseline IOP of 14.27±3.53 mm Hg to mean IOP of 16.54± 4.29, 18.54± 5.50, 19.00± 5.98, 18.82± 5.00 and 22.50±0.71 mm Hg at 2, 4, 6, 8 and 12 weeks follow up respectively. In study group IOP elevation of ≥6 mm Hg from baseline was seen in 17 out of 30 eyes (64.71% males and 35.29%females). The majority of patients belonged to younger age group. An IOP elevation was seen in 58.82% and 88.24% eyes upto 4 and 6 weeks follow up respectively. In 15 out of 17 eyes, IOP was controlled with topical anti-glaucoma medications while 2 eyes required filtering glaucoma surgery. Conclusions: After 4 mg of IVTA injection 57.67% of eyes developed IOP elevation ≥6 mm Hg from baseline. In 88.24% eyes raised IOP was controlled with topical anti-glaucoma medications. There was no statistically significant change observed in retinal nerve fibre layer thickness upto 12 weeks follow up, despite elevated IOP. Besides glaucoma no other complication was observed upto 12 weeks of follow up.
Impact of foliar application of humic acid and the measure time on growth and production of roselle Hibiscus sabdariffa L.

The present study was accomplished to achieve the effect of Humic Acid (HA) spraying on the vegetative and calyxes yield characteristics of Hibiscus sabdariffa L. plants, during May ,22th to December, 31st, 2017, at (Girdarasha) open field, Department of Horticulture, Agricultural Engineering Science College, Salahaddin University. Four levels of HA were sprayed (0, 1, 2, 3 g.l-1) at three frequencies (60, 75 and 90 days after sowing). The data were collected after (4, 8 and 12 weeks of last spraying) for vegetative and reproductive parameters: plant height (cm), number of branches, stem diameter (mm), days to 50% of plants flowering, flower diameter (mm), node sequence of 1st flower, number of fruits. plant-1 , fruit length (mm), fruit diameter (mm), fresh and dry weight of fruits. plant-1 (g) and fresh weight of calyxes. plant-1 (g). The obtained results revealed that all treatments of HA increased significantly both vegetative and reproductive parameters and shortened the number of days to flowering as compared with the control. The application of 2g.l-1 produced the tallest plants. Maximum numbers of branches were obtained from the treatment 3g.l-1 HA. The 2g.l-1 and 3g.l-1 treatments formed the thickest stems. Regarding the reproductive parameters; the highest values of fruit diameter, fruit length, fresh and dry weights of fruits. plant-1, fresh and dry weights of calyxes.plant-1 were recorded with the treatment 3g.l-1 after 8 weeks of the last treatment.
Mecanismos que fortalecen la integración: redes de migrantes y permisos de permanencia en los procesos migratorios

La crisis social desatada por la pandemia del Covid-19 ha agravado la condición de vulnerabilidad de los migrantes venezolanos. Lo anterior genera la necesidad de identificar mecanismos que favorezcan el bienestar de esta población. En este sentido, este documento destaca que las redes de migrantes y la posibilidad de acceder a un permiso de permanencia (caso de estudio PEP-RAMV) son mecanismos que facilitan distintas instancias del proceso migratorio en Colombia. En el caso de las redes, los resultados identifican que estas son indispensables para resolver diferentes necesidades, pero cobran especial relevancia en momentos críticos (llegada a Colombia, enfrentando los estragos de la pandemia, entre otros). Mientras que el permiso de permanencia PEP-RAMV otorgó la posibilidad de acceder a mercados formales, salud y educación, lo cual generó una sensación de respaldo por parte del gobierno a una población que de otra forma tendría profundas dificultades para integrarse a la sociedad colombiana. Para explorar el potencial de estos mecanismos, el siguiente documento describe, de forma general, la importancia de las redes de migrantes y el PEP-RAMV durante los procesos migratorios, luego se señala que ambos son mecanismos diferentes, pero tienen puntos de encuentro y finalmente se describe la situación de ambos en torno a distintas afectaciones en los hogares generados por el Covid-19.
Preparation and diagnosis of Xerogel nanocomposites And Studying Their Effect on TNF-? Level before and after Loading Dexamethason in Male White Rats Induced Rheumatoid Arthritis

The current study aimed to evaluate the mechanism of reducing the effect of (RA) after it was induced inmale white rat with a Complete Freund’s Adjuvant (CFA) at TNF-? level by treating Xerogel Nanoparticlesand dexamethasone nanocompounded (Xerogel / Dexa) . The free Xerogel nanoparticle had a surfaceroughness coefficient of 0.327 nm and the total percentage of volumes was 90% less than 130 nm, and theresults also indicated that induced rheumatoid arthritis causes Significant increase (p <0.05) in the meanconcentration of neoplastic necrosis factor (TNF-? ) in the blood serum of male white rats, as they reacheda concentration level (10.68 ± 461.80) Pg / ml in the positive control group (G2) for six weeks of treatmentcompared with the negative control group G1)), as the concentration level in it reached (69.97±0.88) Pg /ml for the same period, and there was also a significant decrease (P <0.05) in the level of concentration ofTNF-? among members of the G5 group treated with the Xerogel / Dexa nanoparticle, as this concentrationreached (182.98 ± 6.99 ) Pg / ml compared to the positive control groups (G2) treated with the free Xerogel(G3) and the group treated with free Dexa (G4) for a six-week treatment period in these groups as theseconcentrations reached (461.80± 10.68, 483.74± 3.59, 300.32± 4.03) Pg / ml, respectively
Kijkgedrag van kinderen en hun angstreacties op televisienieuws: een surveystudie

Om een actueel beeld te krijgen van angstreacties van kinderen op het NOS Jeugdjournaal is een survey afgenomen onder 892 kinderen (9-12 jaar). Bijna alle participanten (94.5%) kijken regelmatig naar het NOS Jeugdjournaal. Het merendeel van deze kinderen ervaart angstreacties door dit nieuws, maar gemiddeld worden ze slechts een klein beetje bang. Vooral meisjes en jongere kinderen lijken kwetsbaarder voor angstaanjagende nieuwsinhoud.