Miracle-dz/UniFAR-FTUs huggingface dataset:
Incentive mechanisms for managing local subcontractors in international construction projects

In the domain of international construction projects, managing supply chains presents distinct challenges due to the intricate task of coordinating multiple stakeholders within diverse cultural, economic, and regulatory contexts. Prior research highlights the significance of incentive mechanisms and collaborative procurement practices, yet the effectiveness of these strategies in augmenting performance for international projects has not been extensively examined. This investigation explores the effects of financial and non-financial incentives on the performance of global construction projects, with a focus on the mediating role of cooperation. Data were gathered from Chinese international contractors and local suppliers and subsequently analyzed using Structural Equation Modeling. The results reveal two separate pathways of influence. Firstly, financial incentives exhibited substantial direct and indirect impacts on project performance; secondly, while non-financial incentives did not directly affect project performance, they significantly impacted cooperation levels, which in turn mediated the relationship between non-financial incentives and project performance. This study provides essential perspectives for managing international construction projects, emphasizing the critical need for the combined application of financial and non-financial incentives to foster cooperation and ultimately achieve superior project outcomes.
Long Noncoding-RNA Component of Mitochondrial RNA ProcessingEndoribonuclease Promotes Gastric Cancer Cell Multiplication,Migration, and Invasion

Since RMRP was found to target microRNA-766-5p (miR-766-5p) in TNBC cells, it enhanced cell viability anddecreased apoptosis by silencing miR-766-5p. Additionally, RMRP has been proven to be highly involved ineither pathological or physiological processes. Therefore, the study aims to determine whether RMRP promotesthe multiplication, migration, and invasion of gastric cancer cells. The study will overexpress RMRP in GC1401gastric cancer cells and measure cell growth by MTT assay, migration by wound healing assay, and Boyden chamberassay. Positive control is another treatment previously shown to increase cancer cell growth and migration, such asIQGAP3, which, beginning with the early stages of tumor growth, is markedly up-regulated in human stomach cancer.Furthermore, the negative control is DMSO. The study measures miR206 by qRTPCR. If the solution gets dark throughMTT assay, RMRP promotes gastric cancer cell multiplication. If the migration rate is getting quicker according to thewound healing assay, and the number of migration cells increases by Boyden chamber assay, RMRP promotes gastriccancer cell migration. If miR-206 may affect the expression of HIF-1 to control cell growth and ECM buildup, RMRPpromotes gastric cancer cell invasion by acting as a miR-206 sponge for gastric cancer. The RNA component of miRNAprocessing endoribonuclease, the novel biomarker for gastric cancer, promotes gastric cancer cell multiplication,migration, and invasion by acting as a miR-206 loss of function in cell lines for gastric cancer.
Progress in the Application of Traditional Chinese Medicine Treatment in Postoperative Rehabilitation of Colorectal Cancer

: As one of the common malignant tumors of the digestive tract, colorectal cancer has a hidden disease and a poor prognosis. The disease has a high incidence rate and mortality, which seriously threatens the normal life of human beings. At present, the preferred treatment method for this disease is surgery, supplemented by radiotherapy, chemotherapy, and targeted therapy. However, postoperative complications and recurrence rates are high in patients, and radiotherapy and chemotherapy can cause serious adverse reactions, affecting the quality of life of patients. With the continuous development of traditional Chinese medicine and the accumulation of clinical experience, its clinical advantages in preventing and treating adverse reactions after colorectal cancer surgery have become increasingly prominent. Its treatment philosophy is people-oriented, and various internal and external treatment methods are used to alleviate postoperative complications, improve the quality of life of postoperative patients, and prevent disease recurrence and metastasis, which has important clinical value.
EVALUATION OF PARETO/D/1/K QUEUE BY SIMULATION

The finding that Pareto distributions are adequate to model Internet packet interarrival times has motivated the proposal of methods to evaluate steady-state performance measures of Pareto/D/1/k queues. Some limited analytical derivation for queue models has been proposed in the literature, but their solutions are often of a great mathematical challenge. To overcome such limitations, simulation tools that can deal with general queueing system must be developed. Despite certain limitations, simulation algorithms provide a mechanism to obtain insight and good numerical approximation to parameters of queues. In this work, we give an overview of some of these methods and compare them with our simulation approach, which are suited to solve queues with Generalized-Pareto interarrival time distributions. The paper discusses the properties and use of the Pareto distribution. We propose a real time trace simulation model for estimating the steady-state probability showing the tail-raising effect, loss probability, delay of the Pareto/D/1/k queue and make a comparison with M/D/1/k. The background on Internet traffic will help to do the evaluation correctly. This model can be used to study the long- tailed queueing systems. We close the paper with some general comments and offer thoughts about future work.
AN EFFICIENT ESTIMATOR TO MONITOR RAPIDLY CHANGING FOREST CONDITIONS

Extensive expanses of forest often change at a slow pace. In this common situation, FIA produces informative estimates of current status with the Moving Average (MA) method and post-stratification with a remotely sensed map of forest-nonforest cover. However, MA "smoothes out" estimates over time, which confounds analyses of temporal trends; and post-stratification limits gains from remote sensing. Time-series estimators, like the Kalman Filter (KF), better detect and analyze unexpected or rapid changes in dynamic forests. KF is a recursive multivariate model-based estimator that separates complex time-series of panel estimates and multi-sensor remotely sensed data into a sequence of smaller and more manageable components. Population-level results are disaggregated into expansion factors that assure additivity and simplify small area and small domain estimation. Other statistics gauge fit of alternative models to annual FIA panel data, which permits quantitative rankings among alternative cause-effect hypotheses.
Interpretación sismotectónica de las series sísmicas de Lugo (1995 y 1997): Un caso de triggering en una zona continental estable.: Un caso de triggering en una zona continental estable.

El noroeste de la Peninsula Iberica ha experimentado un aumento considerable de la actividad sismica entre el ano 1979 y el 2002, a pesar de ser considerada como una zona sismicamente estable. Los mecanismos focales publicados hasta la fecha en trabajos previos para los eventos principales de las series de Lugo de 1995 (4,6) Y 1997 (5,1) difieren completamente en funcion. del metodo de calculo utilizado. El presente trabajo se ha desarrollado con el objetivo de determinar los mecanismos de foco mas coherentes con la geologia local utilizando datos geologico-estructurales de campo y sismotectonicos. Asimismo, se ha realizado una modelizacion de las modificaciones de esfuerzos de Coulomb estaticos generadas por la primera serie con el fin de identificar posibles relaciones geneticas. Entre todos los modelos de esfuerzos el que mejor explica la distribucion espacial de la serie de 1997 es el asociado a una falla oblicua inverso-direccional similar a la falla de Baralla, que por tanto se propone como posible fuente sismica. La evolucion de las series sismicas apoya el funcionamiento de un proceso de triggering generado por la modificacion de esfuerzos de Coulomb causada por el primer evento de magnitud 4,6 en 1995. La posicion mas profunda de la segunda serie parece indicar que las modificaciones del esfuerzo de fractura de Coulomb que ocasiono la primera serie desestabilizo un segmento mas profundo de la misma falla que un ano mas tarde genero la serie de 1997
Using a Target Product Profile (TPP) to guide innovation for future In Vitro Diagnostic (IVD) developments in the United States

ABSTRACT A well-developed Target Product Profile (TPP) is central to successful in vitro diagnostic (IVD) device developments. A TPP is a key document that outlines the desired attributes of a target product that is aimed at a particular disease. The TPP framework can highlight technological gaps and focus developments on meeting specific needs that advance the field. A survey of various diagnostic technologies, such as those employed for respiratory disease diagnosis, reveals significant innovations that have been accomplished during the COVID-19 public health emergency. Nevertheless, the entire IVD diagnostic landscape continues to evolve, and it is important for device developers to identify the challenges and set appropriate targets to avoid pitfalls. While a TPP does not necessarily guarantee market success of an IVD, it is an important tool that can help developers define appropriate criteria for their device. A TPP can guide them through the multi-faceted development process to meet consumer demands, while ensuring clinical utility, safety, and effectiveness of their products. The following discussion highlights the TPP process for IVD device developments through the application of the basic tenets in various case studies. The aim is to help developers traverse the proverbial ‘valley of death’, where many great concepts fail to reach market success, and to encourage positive developments in the field beyond current IVD device limitations.
2DG Affects Liver Cancer Cell Ferroptosis By Affecting

Cancer cells are characterized by high proliferation but at the expense of enhanced metabolic rates. If the activeoxygen content in the cell exceeds the average level, cancer cells activate antioxidant defenses against this increase.Ferroptosis occurs when glutathione levels are reduced due to a lack of cysteine in the cell. Ferroptosis is a new type ofasymptomatic apoptosis. We chose to investigate the sensitivity of cancer cells to the effect of 2DG on ferroptosis. Theseinclude some effects of 2DG on intracellular NADPH solubility and NADPH’s role in converting cystine to cysteine incancer cells. The effect of cysteine on glutathione, the inhibitory effect of glutathione on ROS in cancer cells, and theaccumulation of ROS can lead to ferroptosis in cancer cells.
Retrieval of Surface Lambert Albedos from the Mars Reconnaissance Orbiter CRISM Data

CRISM DATA. P. C. McGuire, M. J. Wolff , R. E. Arvidson, M. D. Smith, R. T. Clancy S. L. Murchie, J. F. Mustard , S. M. Pelkey, T. Z. Martin and the MRO/CRISM Team, McDonnell Center for the Space Sciences, Dept. of Earth & Planetary Sciences and Dept. of Physics, Campus Box 1169, Washington University, Saint Louis, MO 63130, Email: mcguire@wunder.wustl. edu, Space Science Institute, 4750 Walnut Street, Suite 205, Boulder, CO 80301, NASA Goddard Space Flight Center, Mail Code 693, Greenbelt, MD 20771, Applied Physics Laboratory, Laurel, MD 20723, Department of Geological Sciences, Box 1846, Brown University, Providence, RI 02912, Jet Propulsion Laboratory, 4800 Oak Grove Drive, Pasadena CA 91109.
Snow Albedo’s Dependence on Solar Zenith Angle from In Situ and MODIS Data

Abstract Since snow cover is one of the fastest modi fications to the land surface albedo, the treatment of snow-covered surface albedo is important for the simula tion of land processes in weather and climate models. A simple formulation is developed here to represent the so lar zenith angle (SZA) dependence of albedo under maximum snow cover condition on the basis of Moderate Resolution Imaging Spectroradiometer (MODIS) Bidirectional Reflectance Distribution Function (BRDF) algorithm. The SZA dependence of black-sky (or direct) albedo is weaker under snow condition than that under snow-free condition, and it does not differ much among different vegetation types. The blue-sky albedo (or combined albe do from direct and diffuse radiations) based on the above formulation and in situ diffuse ratio of solar radiation is consistent with in situ data from two Canadian sites (grassland and evergreen needleleaf forest) and one U.S. grassland site. In particular, the SZA dependence of blue-sky snow albedo is almost always weak because of high diffuse ratios for high SZA in winter. With the snow al bedo formulation from this study and snow-free albedo formulations from the authors’ previous studies, albedos with partial snow cover can be obtained as the snow fraction-weighted average of snow and snow-free albedos.
Comparing the Effectiveness of the Ketogenic Diet and Intermittent Fasting on 12-Weeks Weight Management in Women with Obesity

The optimal dietary strategies for weight loss and maintenance have been at the center of debate for decades. Proponents of each camp presented their assertions, but they could not approve of one diet due to the sophisticated determinants and limited empirical evidence. This study aims to compare the effectiveness of the Ketogenic diet and Intermitting fasting concerning weight loss and risk factors of cardiovascular outcomes. Fifty-eight obese female participants agreed to participate in the 12-week randomized clinical trial followed by a 6-months observational period. The participants are randomly assigned to the ketogenic diet with an aggressive reduction in carbohydrate content or intermitting fasting that involve a restricted meal time. The results reveal that the ketogenic diet will result in rapid, short-term weight loss. In contrast, intermitting fasting will demonstrate better long-term weight maintenance and no noticeable correlation with reducing risk factors of cardiovascular diseases. In conclusion, this study indicates no absolute advantage to any single treatment.
Regularization parameter estimation for feedforward neural networks

Under the framework of the Kullback-Leibler (KL) distance, we show that a particular case of Gaussian probability function for feedforward neural networks (NNs) reduces into the first-order Tikhonov regularizer. The smooth parameter in kernel density estimation plays the role of regularization parameter. Under some approximations, an estimation formula is derived for estimating regularization parameters based on training data sets. The similarity and difference of the obtained results are compared with other work. Experimental results show that the estimation formula works well in sparse and small training sample cases.
Six Arguments for Vygotskian Pragmatism in Deaf Education: Multimodal Multilingualism as Applied Harm Reduction

Abstract:Deaf education research and practice have not always lived up to the ideal of improving deaf students' lives. Consequently, we have constructed novel arguments supporting deaf pedagogy using pragmatic ethics, the aim of which is to increase benefit and decrease harm to individuals and society. The ideal of harm reduction asks the pragmatist to pursue the path of action least likely to result in injury to others. Besides applying ideas that reduce harm, educators must also increase benefits for deaf students. Our analysis synthesizes Vygotskian perspectives on deaf pedagogy and pragmatic ideals about reducing harm and increasing benefit. We propose six arguments that can enable deaf educators to think about and enact deaf-positive concepts and strengths-based classroom interactions, including the use of sign language, images, and text, among other modes, such as speech. Our goal is to reduce the threat of harm from language deprivation.
Change through tourism: Resident perceptions of tourism development

Change through Tourism: Resident Perceptions of Tourism Development. (December 2006) Minsun Doh, B.S., Korea University; M.S., Texas A&M University Chair of Advisory Committee: Dr. Carl Scott Shafer Many view tourism as a tool for community development. Especially in the rural areas experiencing economic hardships, tourism often is considered an instrument for revitalization of a local economy helping to improve quality of life and protect natural and cultural resources. However, many researchers have raised concerns about an overly optimistic view by asserting that tourism development inevitably affects the corresponding community. Empirical studies suggest that development of tourism brings environmental, sociocultural, and economic changes to the community where it is developed. Thus, it is important that planners look at the attitudes of local people towards tourism development in their community before an actual development takes place. The conceptual basis of this study is development and change theory and empirical findings of tourism impact research. This study provides information to assist in understanding questions related to the rural communities’ tourism planning process in
Some effects of forest preservation

Long-term preservation (no cutting) of a deciduous forest stand in New Hampshire is leading toward stable populations of beech, sugar maple, striped maple, mountain maple, and hobblebush, coupled with a decline or complete disappearance of other woody species. The humus has stabilized at a depth no greater than that of cut stands. Nitrate discharge in the streams is higher than what is normally found in uncut stands, possibly because of stability in standing crop and humus.
Baroclinic Tides: Theoretical Modeling and Observational Evidence

1. General background 2. Linear baroclinic tides over variable bottom topography 3. Combined effect of horizontal density gradient and bottom topography in the dynamics of linear baroclinic tides 4. Topographic generation of nonlinear baroclinic tides 5. Evolutionary stages of baroclinic tides 6. Generation mechanism at different background conditions 7. Three-dimensional effects of baroclinic tides.
Deletion of the GAS Regulatory Sequence of IFN- γ Induced Gene(ICAM-1) by Using CRISPR Cas9 to Decrease the Jak3/Stat3Dependent IDO Expression to Repress Tumor Cells Development

IDO is a checkpoint molecule that regulates T-cell proliferation. Since IDO contributes to T cell death and creates anenvironment for cancer cells to grow, it is necessary to regulate IDO expression. Previous studies demonstrated thatIFN-gamma-induced genes would indirectly activate IDO expression through the Jak/3 pathway, and ICAM-1 is oneof the IFN-gamma-induced genes. This work investigates the effect of ICAM-1 on IDO expression and the effect of2 GAS segment knockouts on ICAM-1 expression. CRISPR-Cas9, heat shock transformation, PCR, and restrictiondigestion are used to knock out the target sequence (GAS) and insert the successful knocked-out gene into the E. coli.RT-PCR is utilized to measure the expression level of ICAM-1 and IDO after the introduction of successfully knockedout genes. The possible result of this work presents that both GAS gene knockouts are thriving; the new gene withoutGAS – 2787 bps expresses less ICAM-1 protein than the gene without GAS – 115 bps, and ICAM-1 does not affect IDOexpression at all. Results of this work indicate that the GAS sequence that is farther away from the ICAM-1 RBS sitemight decrease the ICAM-1 expression level less than does GAS sequence that is nearer to RBS, and ICAM-1 might nothave any direct impact on IDO expression, which means that tumor cell development cannot be inhibited by regulatingICAM-1 expression. Future studies could research more on functions of IFNgamma-induced genes other than ICAM-1and their relationships with IDO expression.
Clearing the air : 25 years of the convention on long-range transboundary air pollution

The UNECE Convention on Long-range Transboundary Air Pollution is one of the oldest multilateral international treaties to protect the environment, as well as being one of the most successful. This publication marks the 25th anniversary of the Convention and includes contributions from experts, delegates, chairmen and members of the secretariat to the Convention which explore its framework, past successes, current activities and future challenges.
IL-17: Balancing Protective Immunity and Pathogenesis

The biological role of interleukin 17 (IL-17) has been explored during recent decades and identified as a pivotal player in coordinating innate and adaptive immune responses. Notably, IL-17 functions as a double-edged sword with both destructive and protective immunological roles. While substantial progress has implicated unrestrained IL-17 in a variety of infectious diseases or autoimmune conditions, IL-17 plays an important role in protecting the host against pathogens and maintaining physiological homeostasis. In this review, we describe canonical IL-17 signaling mechanisms promoting neutrophils recruitment, antimicrobial peptide production, and maintaining the epithelium barrier integrity, as well as some noncanonical mechanisms involving IL-17 that elicit protective immunity.
STATIC ANALYSIS & IDENTIFICATION OF MALWARE IN SANDBOX ENVIRONMENT

: Usage of internet is a daily routine nowadays. From office work, e-commerce, banking, education, business, entertainment, stock market, everywhere we depend abundantly on internet. The numbers of internet users are growing largely day by day and so does cyber crimes. Malware is like a weapon used for cyber crime. Analysis of malware is important to prevent malware's action in today's cyber world. This paper is written of static analysis and identification of malware in sandbox environment. Here, in windows 7 ultimate sandbox, static malware analysis is performed using some tools and the malware is identified. Also some details about the malware attached file type; characteristics and functions of the malware, which discover by tools; have been discussed in this research paper.
A Periglacial Analog for Landforms in Gale Crater, Mars

Summary: Several features in a high thermal inertia (TI) unit at Gale crater can be interpreted within a periglacial framework. These features include polygonally fractured terrain ( cf. ice-wedge polygons), circumferential patterns of polygonal fractures ( cf . relict pingos with ice-wedge polygons on their surfaces), irregularly-shaped and clustered depressions ( cf. remnants of collapsed pingos and ephemeral lakes), and a general hummocky topography ( cf . thermokarst). This interpretation would imply a major history of water and ice in Gale crater, involving permafrost, freeze-thaw cycles, and perhaps ponded surface water. Background: Gale crater is a ~150 km diameter, impact structure located at 5 o 22’S, 137o51’E. It sits on the dichotomy that separates the southern highlands from the northern lowlands. Gale includes a 5.5 km high, central mound of sediments that is surrounded by a moat-like topographic low. MSL landed on the low, close to high a region of early interest because of its location distal to an alluvial fan and its high TI (Fig. 1). The MSL rover will analyze this unit at Yellowknife Bay (Fig. 2). Geomorphology of the high TI unit is presented here, based on HiRISE data.