Miracle-dz/UniFAR-FTUs huggingface dataset:
Bayes designs for multiple linear regression on the unit sphere

We deal with experimental designs minimizing the mean square error of the linear BAYES estimator for the parameter vector of a multiple linear regression model where the experimental region is the k-dimensional unit sphere. After computing the uniquely determined optimum information matrix, we construct, separately for the homogeneous and the inhomogeneous model, both approximate and exact designs having such an information matrix.
A Search for Polarization in Diffuse Interstellar Bands toward HD 197770

Spectroscopy and spectropolarimetry in the wavelength range 5600-5800 Å have been obtained for the line of sight toward HD 197770, which has a reported polarized 2175 Å extinction bump. The 5780 and 5797 Å diffuse interstellar bands (DIBs) are anomalously weak (by a factor >2) with respect to reddening, whereas the broader 5778 Å band appears to be anomalously strong. None of these bands shows detectable polarization in excess of that in the continuum; aligned classical grains cannot be the carriers of these bands. The ratio of polarization to optical depth in the DIBs is marginally smaller than would be expected if the DIB carriers were the small, presumably carbonaceous, grains responsible for the 2175 Å absorption.
Association of NOD1 and NOD2 Polymorphisms With Susceptibility to Subacute Sclerosing Panencephalitis

Background: Subacute sclerosing panencephalitis is a progressive neurodegenerative disease that is a late complication of measles infection. However, to date, the pathogenesis of subacute sclerosing panencephalitis is still not explained; both viral and host factors seem to be associated. The present study aimed to investigate the relationship between NOD1 and NOD2 gene variants and subacute sclerosing panencephalitis. Methods: The gene variants of NOD1 (rs2075820 and rs2075818) and NOD2 (R334Q and R334W) were explored in 64 subacute sclerosing panencephalitis patients and 70 controls using polymerase chain reaction–restriction fragment length polymorphism (PCR-RFLP). Results: The frequencies of the AA genotype and A allele of rs2075820 (NOD1; c.796G>A) polymorphism were lower in patients compared with controls (P = .022 and .014, respectively). The presence of the A allele of rs2075820 may be considered as a protective factor for subacute sclerosing panencephalitis. There was a significant difference between the groups in rs2075818 (NOD1 G/C) polymorphism, and the CC genotype increased the risk of subacute sclerosing panencephalitis by 3.471-fold. The carriers of the C allele of rs2075818 (G/C) had a 1.855-fold susceptibility to subacute sclerosing panencephalitis (P = .018). The GC genotype might be associated with subacute sclerosing panencephalitis susceptibility in the patients compared with patients without having that haplotype (P = .03). Conclusions: Thus, we identified an association between subacute sclerosing panencephalitis and the rs2075820 (NOD1 G/A) and rs2075818 (NOD1 G/C) polymorphisms. These findings implicate a possible effect of this genetic polymorphism in susceptibility to subacute sclerosing panencephalitis, which needs to be confirmed in bigger populations.
Reply: The Persistent Absence of Empirical Evidence for Free-Riding in Global Climate Politics

Abstract Kennard and Schnakenberg (KS) raise three concerns regarding Aklin and Mildenberger (“Prisoners of the Wrong Dilemma: Why Distributive Conflict, Not Collective Action, Characterizes the Politics of Climate Change,” Global Environmental Politics 20 (4): 4–27). In this response, we delineate where we agree and where we disagree with KS. We then consider whether the model presented by KS changes our assessment that free-riding concerns are not currently the binding constraint on global climate politics. We conclude with a refined statement of our original claim.
Near-infrared and optical emission-line structure of the Keyhole Nebula in NGC 3372

Narrow-band infrared and optical images of the Keyhole Nebula in NGC 3372 reveal which structures are caused by extinction, and show the underlying morphology of photoionized and shock-excited gas. Dark clouds conspire with ionized gas to create the apparent keyhole shape, which is prominent at blue wavelengths and less apparent in the infrared. The Paβ/Hα line ratio shows the spatial distribution of foreground extinction. The wavelength dependence of this extinction indicates a reddening law with R≈4.8, different from the normal interstellar medium. This confirms previous estimates of reddening toward the Carina Nebula determined from stellar photometry, and reveals that the anomalous extinction is patchy and within the H ii region. The morphology of the ionized gas is different from the extinction clouds; it shows an edge-on ionization front running NE to SW, with a limb-brightened indentation that forms the upper outline of the keyhole shape. A fast polar wind from η Carinae may have punctured the ionization front, since the indentation is directly along a projection of the polar axis of the star. This is supported by the morphology of shock-excited gas revealed by a high [S ii]/Hα ratio. High-excitation gas emitting [O iii] and He i has a smoother distribution. Molecular clumps in the region are also discussed.
Anomaly Gait Detection in ASD Children based on Markerless-based Gait Features

Children with autism are known for their difficulties in social interaction, communication, and behaviour characteristics. Hence, this study proposed to develop a markerless-based gait method for anomaly gait detection in children with autism spectrum disorder (ASD). Firstly, a depth sensor is used during walking gait data collection of the 23 ASD children and 30 typical healthy developing (TD) children. Further, these walking gait data are divided into the Reference Joint (REF) and Direct Joint (DIR) features. For each type, five sets of features are derived that represents the whole body, upper body, lower body, the right and left side of the body. The three classifiers used to validate the effectiveness of the proposed method are Naïve Bayes (NB), Support Vector Machine (SVM), and Artificial Neural Network (ANN). Results showed that the highest accuracy, precisely 94.22%, is achieved using the ANN classifier with DIR1 gait features representing the whole body. The highest sensitivity and specificity obtained are 94.49% and 93.93% accordingly. In addition, the proposed markerless model using the DIR1 gait features and the ANN as classifier also outperformed previous studies that have utilised the marker-based model. This promising result showed that the proposed method could be used for early intervention for the ASD group. The markerless-based gait technique also has fewer experiment protocols, thus causing the ASD children to feel more comfortable.
The Effects of Spatial Characteristics and Visual and Smell Environments on the Soundscape of Waterfront Space in Mountainous Cities

The soundscape of waterfront space in mountainous cities (WSMC) can affect people’s physical and mental health. Taking seven WSMCs in Chongqing, China, as the study area, this study aimed to investigate the soundscape and explore the influence of spatial characteristics and visual and smell environments on the soundscape of WSMCs through a sensewalking approach. The results show that the soundscape evaluations of WSMCs are of poor quality, and traffic sounds are dominant (33%). Among spatial characteristics, the position relative to the road (including vertical and horizontal distances) had a greater impact than other spatial indicators on soundscape evaluations. Elevation was positively correlated with the A-weighted equivalent sound level (LAeq) and negatively correlated with the soundscape comfort degree (SCD). In terms of visual elements, the proportions of paved ground, pedestrians, and buildings had negative effects on the soundscape, while those of the sky, water, and natural terrain had positive effects. High visual and smell environment quality can enhance soundscape evaluations, although the smell environment had a greater impact on the SCD than the visual environment in WSMCs. Finally, this study summarizes the recommended values of spatial characteristics and visual and smell environment indicators to put forward references for the soundscape design of WSMCs.
Effect of low level laser therapy on orthodontic miniscrew displacement (A randomized controlled clinical trial)

Mohamed Elzoheiry, Champollion St, Azarita, Alexandria, Egypt, mohamed.awad. dent@alexu.edu. eg, 01007036198 1 Effect of low level laser therapy on orthodontic miniscrew displacement (A randomized controlled clinical trial) Mohamed Elzoheiry 1 resident, Nadia Elharouni 2 professor, Sherief Abdel-Haffiz 3lecturer 1. Resident, Department of Orthodontics, Faculty of Dentistry, Alexandria University, Alexandria, Egypt. (Email: Mohamed.awad.dent@alexu.edu.eg).
Magnetic and electric properties of (Fe, Co)/(Si, Ge) multilayers

We review selected results concerning the interlayer exchange coupling in Fe/SixFe1−x, Fe/Ge and Co/Si layered structures. Among the ferromagnet/semiconductor systems, Fe/Si structures are the most popular owing to their strong antiferromagnetic interlayer coupling. We show that such interaction depends not only on semiconducting sublayer thickness, but also on deposition techniques and on the chemical composition of the sublayer as well. In similar heterostructures e.g. Fe/Ge, antiferromagnetic coupling was observed only in ion-beam deposited trilayers at low temperatures. In contrast, in Fe/Ge multilayers deposited by sputtering, no such coupling was found. However, when the Ge is partially substituted by Si, antiferromagnetic interlayer coupling appears. For Co/Si multilayers, we observed a very weak exchange coupling and its oscillatory behavior. The growth of Co on Si occurs in an island growth mode. The evolution of magnetic loop shapes can be successfully explained by the interplay between interlayer coupling and anisotropy terms.
Ex vivo optical characterization of in vivo grown tissues on dummy sensor implants using double integrating spheres measurement

Near infrared spectroscopy offers a promising technological platform for continuous glucose monitoring in the human body. NIR measurements can be performed in vivo with an implantable single-chip based optical NIR sensor. However, the application of NIR spectroscopy for accurate estimation of the analyte concentration in highly scattering biological systems still remains a challenge. For instance, a thin tissue layer may grow in the optical path of the sensor. As most biological tissues allow only a small fraction of the collimated light to pass, this might result in a large reduction of the light throughput. To quantify the effect of presence of a thin tissue layer in the optical path, the bulk optical properties of tissue samples grown on sensor dummies which had been implanted for several months in goats were characterized using Double Integrating Spheres and unscattered transmittance measurements. The measured values of diffuse reflectance, diffuse transmittance and collimated transmittance were used as input to Inverse Adding-Doubling algorithm to estimate the bulk optical properties of the samples. The estimates of absorption and scattering coefficients were then used to calculate the light attenuation through a thin tissue layer. Based on the lower reduction in unscattered transmittance and higher absorptivity of glucose molecules, the measurement in the combination band was found to be the better option for the implantable sensor. As the tissues were found to be highly forward scattering with very low unscattered transmittance, the diffuse transmittance measurement based sensor configuration was recommended for the implantable glucose sensor.
Residual Neural Network in Genomics

Residual neural network (ResNet) is a Deep Learning model introduced by He et al. in 2015 to enhance traditional convolutional neural networks proposed to solve computer vision problems. It uses skip connections over some layer blocks to avoid vanishing gradient problem. Currently, many researches are focused to test and prove the efficiency of the ResNet on different domains such as genomics. In fact, the study of human genomes provides important information on the detection of diseases and their best treatments. Therefore, most of the scientists opted for bioinformatics solutions to get results in a reasonable time. In this paper, our interest is to show the effectiveness of the ResNet model on genomics. For that, we propose two new ResNet models to enhance the results of two genomic problems previously resolved by CNN models. The obtained results are very promising and they proved the performance of our ResNet models compared to the CNN models.
Polypyrimidine-Tract-Binding Protein Isoforms Differentially Regulate the Hepatitis C Virus Internal Ribosome Entry Site

Translation initiation of the hepatitis C virus (HCV) mRNA depends on an internal ribosome entry site (IRES) that encompasses most of the 5′UTR and includes nucleotides of the core coding region. This study shows that the polypyrimidine-tract-binding protein (PTB), an RNA-binding protein with four RNA recognition motifs (RRMs), binds to the HCV 5′UTR, stimulating its IRES activity. There are three isoforms of PTB: PTB1, PTB2, and PTB4. Our results show that PTB1 and PTB4, but not PTB2, stimulate HCV IRES activity in HuH-7 and HEK293T cells. In HuH-7 cells, PTB1 promotes HCV IRES-mediated initiation more strongly than PTB4. Mutations in PTB1, PTB4, RRM1/RRM2, or RRM3/RRM4, which disrupt the RRM’s ability to bind RNA, abrogated the protein’s capacity to stimulate HCV IRES activity in HuH-7 cells. In HEK293T cells, PTB1 and PTB4 stimulate HCV IRES activity to similar levels. In HEK293T cells, mutations in RRM1/RRM2 did not impact PTB1′s ability to promote HCV IRES activity; and mutations in PTB1 RRM3/RRM4 domains reduced, but did not abolish, the protein’s capacity to stimulate HCV IRES activity. In HEK293T cells, mutations in PTB4 RRM1/RRM2 abrogated the protein’s ability to promote HCV IRES activity, and mutations in RRM3/RRM4 have no impact on PTB4 ability to enhance HCV IRES activity. Therefore, PTB1 and PTB4 differentially stimulate the IRES activity in a cell type-specific manner. We conclude that PTB1 and PTB4, but not PTB2, act as IRES transacting factors of the HCV IRES.
Audit and Feedback in the Hospitals of the Emergency Networks in the Lazio Region, Italy: A Cross-Sectional Evaluation of the State of Implementation

Audit and Feedback (A&F) is an effective multidimensional strategy for improving the quality of care. The optimal methods for its implementation remain unclear. This study aimed to map the state of art of A&F strategies in the hospitals involved in a time-dependent emergency network. For these purposes, a structured questionnaire was defined and discussed within the research group. This consists of 29 questions in three sections: (1) characteristics of the structure, (2) internal feedback systems, and (3) external feedback systems. All structures involved in the network were invited to participate in the e-survey by indicating a Health Management representative and a clinical representative for the Cardiovascular (CaV) and/or for the Cerebrovascular area (CeV). Of 20 structures invited, a total of 13 (65%) responded to the survey, 11 for the CaV area and 8 for the CeV area. A total of 10 of 11 (91%) facilities for the CaV area and 8/11 (75%) for the CeV area reported that they perform A&F activities. All facilities perform at least one of the activities defined as “assimilating A&F procedures. ” The most frequent is the presentation and discussion of clinical cases (82% CaV and 88% CeV) and the least is the identification of responsible for improvement actions (45% CaV and 38% CeV). In 4/10 (40%) facilities for the CaV area and 4/8 (50%) for the CEV area, corrective actions are suggested or planned when the feedback is returned. These results confirm the need to define, in a synergistic way with the relevant stakeholders, an effective and agreed A&F intervention to improve the level of implementation of A&F strategies.
Identities concerning canonical conformal mappings

Every Riemann half-surface becomes a closed Riemann surface, when it is inverted with respect to any one of its boundary components and the original boundary is then sewn with its inverted image by idential coordination* We may suppose further without loss of generality that the fixed circle bearing the projection of the boundary of a Riemann half-surface is coincident with the real axis of a complex plane* The closed Riemann surface obtained by the duplication process is then generated by an irreducible algebraic equation with merely real coefficients*
Screening and Probiotic Properties of Lactic Acid Bacteria with Potential Immunostimulatory Activity Isolated from Kimchi

The modulation of the immune system is a major mechanism through which probiotics exert beneficial effects on health. Probiotics, including lactic acid bacteria (LAB), have been reported to enhance innate immunity. The purpose of this study was to screen for LAB strains with excellent immunostimulatory activity isolated from kimchi. We selected five promising strains (Limosilactobacillus fermentum MG5489, Lactococcus lactis MG5542, Lacticaseibacillus paracasei MG5559, Latilactobacillus sakei MG5468, and Latilactobacillus curvatus MG5609) that exhibited immune-stimulating effects by inducing the production of nitric oxide (NO) and pro-inflammatory cytokines such as tumor necrosis factor (TNF)-α, interleukin (IL)-6, and IL-1β in RAW264.7 cells. The selected strains significantly increased phagocytic activity of RAW264.7 cells and nuclear factor-κB (NF-κB) activation. Furthermore, the safety of the selected strains was determined using hemolysis and antibiotic susceptibility tests. The stabilities and adhesion abilities of these strains in the gastrointestinal tract (GIT) were also determined. Taken together, these findings suggest that the strains selected in this study have the potential to be novel probiotics to enhance immunity.
Effect of Primary Care on Reducing Rates of Hospitalization Among Chronic Obstructive Pulmonary Disease Patients

The normal course of Chronic obstructive pulmonary disease (COPD) includes a progressive reduction in lung function, exacerbations that necessitate primary care intervention or hospital admission, a steady decline in quality of life, and a shorter life expectancy. COPD is one of the ambulatory or primary care-sensitive illnesses for which it is hypothesized that efficient primary care management will lower the probability of hospital admission. Long-acting beta-agonist and inhaler steroid combination therapy improves spirometric results and overall health while lowering the annual risk of COPD exacerbations. Use of two or more treatment modules based on models designed specifically for chronic care delivery in developed countries have proven successful in lowering hospitalizations as well. Access to other therapies, such as pulmonary rehabilitation, acute exacerbation evaluation programs, and community or hospital-based respiratory specialists, may also be important. The goal of interventions to lessen the prevalence of COPD in underserved areas has to focus on locally driven integrated solutions, such as media campaigns to raise awareness and persuade at-risk individuals to get tested, as well as training for primary care workers on the significance and advantages of earlier detection and effective operation of chronic obstructive pulmonary disease. Importantly, uptake of influenza vaccination has demonstrated a link with hospital admission rates at the practice level. Proposed solutions for lowering hospitalization and reducing exacerbations among patients with COPD include greater access to pulmonary rehabilitative care, more rigorous implementation of smoking cessation programs and availability of modern long-acting medications.
Humidity sensors based on pentacene thin-film transistors

When a pentacene thin-film transistor is exposed to humidity, its saturation current decreases. This decrease was found to be reversible and can therefore be used to measure the amount of relative humidity in atmosphere. The sensitivity was found to depend on the thickness of the pentacene layer. The microscopic origin of the sensing mechanism is discussed.
Relation between Intensive Care Nurses' Job Embeddedness and Workplace Thriving

Background: Maintaining stability for intensive care nurses is crucial to confirm the quality of care. Thriving is an essential component of sustainable development for nurses as well as organizations and job embeddedness is a key factor for nurses to thrive in the workplace. Aim of the study : Explore the relation between intensive care nurses' job embeddedness and workplace thriving. Method: Design : A correlational design was utilized. Subjects : The study's subjects consisted of all (183) intensive care nurses Tools : Two tools were used for data collection, Intensive Care Nurses’ Job Embeddedness Questionnaire and Intensive Care Nurses’ Workplace Thriving Questionnaire. Results: The results showed that 69.4% of intensive care nurses had a low level and around one quarter (24%) had a moderate level of total job embeddedness. 54.1 of intensive care nurses had a moderate level, and 25.1% had a low level regarding the total workplace thriving. Conclusion : Intensive care nurses’ had a low level of both job embeddedness and workplace thriving. There was a highly statistically significant correlation between total intensive care nurses’ job embeddedness and their total workplace thriving. Recommendations : The hospital managers develop strategies to enhance nurses’ embeddedness and their workplace thriving by providing career opportunities within the hospital, involving them in decision-making and mentoring programs for newly hired nurses.
Polarized optical absorption and photoluminescence measurements in single-crystal thin films of 4′-dimethylamino-N-methyl-4-stilbazolium tosylate

Single-crystal thin films of the anhydrous (red) and the hydrated (orange) phases of the organic salt 4′-dimethylamino-N-methyl-4-stilbazolium tosylate were grown by a modification of the shear method. The optical absorption coefficients of the films were measured with light polarized along and normal to the dipole/molecular axis at both resonant and off-resonant wavelengths, and a strong dichroism was observed at the resonant wavelengths. The absorption measurements are important considering potential applications of these films (red phase) in high-speed single-pass thin-film electro-optic modulators [M. Thakur, J. Xu, A. Bhowmik, and L. Zhou, Appl. Phys. Lett. 74, 635 (1999)] and other photonic devices. Highly polarized photoluminescence (PL) has been observed in these films. The PL efficiencies of the red- and orange-phase single-crystal films were measured to be about 12% and 14%, respectively, which are significantly higher than the maximum PL efficiency measured in solution (3%).
Parameter uncertainty analysis on acoustic response in fluid filled poroelastic media

This paper examines the effect of input parameter uncertainty in the prediction of acoustic response in ocean sediment. Due to the relatively large number of physical parameters in the model, and the difficulty of their direct measurement in the ocean environment, uncertainty in the predicted acoustic response is expected. Utilizing a second order Taylor series expansion, this paper demonstrates a methodology for estimating the output uncertainty in terms of statistical moments from the input uncertainty. The methodology is then tied to a practical procedure that uses engineering measurements and empirical relations to determine parameters such as shear modulus, bulk modulus, and permeability, from porosity. A related issue of pore size distribution and its effect on acoustic response is also investigated.