SESJA PLAKATOWA

test — immediately after discontinuation of dobutamine because of symptoms or heart rate limit. Results: We observed rather limited diagnostic value of isolated chest pain and ECG changes during DSE in detection of CAD with slightly higher accuracy of chest pain. Nevertheless both parameters showed moderate, exceeding 70% negative predictive value in women and positive predictive value in men, see table 1. Conclusions: ECG and chest pain changes during DSE showed moderate and gender -dependent diagnostic utility. A girl with ventricular preexcitation underwent an echocardiograp hy examination which revealed an aneurysmatic formation at the level of atrio-ventricular septum. Cardiac magnetic resonance imaging was performed and an electrophysiological study was conducted.Case description: A 12-year-old girl was presented to a pediatric cardiologist because of the heart murmur. The electrocardio graphic examination revealed ventricular preexcitation. Echo cardiography was performed and interpreted as follows: a giant appendiform aneurysmatic formation at the level of atrio-ven tricular septum without shunt, with normal valves and normal cardiac chambers. The chest X-ray was unremarkable. The girl was regularly followed-up. At the age of 14 she was admitted to hospital with a cardiogenic shock due to atrioventricular reentry tachycardia. The antiarrhythmic therapy was only partially suc -cessful. Cardiac magnetic resonance imaging was performed and confirmed the presence of a complex aneurysm of the atrio --ventricular septum, stretching into the right atrium and behind the left atrium. The aneurysm entrance measured 2.5 cm and its body dimensions were 4.1x2. 4x1.8 cm. No accompanying ventricular septum defect was evident. The electrophysiological study was conducted and revealed the abnormal anatomy of the coronary sinus: the coronary sinus ostium narrowed by the aneurysm and a broad posteroseptal accessory pathway with a ventricular insertion on the left side and an atrial insertion on both the left and right sides. The accessory pathway was probably incorporated in the aneurysm. Multiple radiofrequency applications did not eliminate accessory pathway conduction. We decided to apply a calcium- channel- blocker therapy and for the last year she has been feeling well although she has been suffering from sporadic, up to 10 minute long, clinically insignificant atrioventricular reentry tachycardia. each were HRA of macro on MS Excel software. The time between consecutive RR intervals was assessed. The heart from the previous one, and the sequential monotonic changes in RR interval (acceleration or deceleration runs) were discriminated. Background: The complexity of atrial arrhythmias makes the electrophysiological characterization of the re-entrant processes difficult with conventional mapping techniques performed during an electrophysiological study. The aim of our study was to evaluate new algorithms that in the future may enable to visualize reentrant waves with a limited number of electrodes placed within the atria using commonly used intracardiac catheters. One of the potential techniques used for such visualization is the current source density mapping, which we test in our study. Methods and results: We performed a simulation of re-entrant electrical activation in a two-dimensional 5 cm x 5 cm tissue strip using a Fenton-Karma model of cardiac tissue, obtaining maps of transmembrane potential. Then, to model an intracardiac electrogram measurement, unipolar extracellular potentials were reconstructed for different configurations of electrode placement in the tissue strip. Two methods of Current Source Density were applied [1–2] to reconstruct the electrical activation in the whole tissue strip using only the measurements from simulated unipolar electrodes. As a result, we obtained reconstructed current source density and potential for the whole strip, which was compared with underlying simulated transmembrane potential. This was repeated for different activation patterns. Conclusions: Simulations show that even for a limited number of electrodes, such as in the case of penta-array catheters, it is possible to reconstruct the true direction and region of activa tion under the tissue area covered by electrodes. However, the reconstruction of the size of the activation and shape still needs to be improved for the method to be clinically useful. The 3D Heart Anatomy Animation Video is an exploration into the multiple and unconventional ways a beating heart might be visu ally represented using the latest computer graphics technology. In this case, the general aim of this project was to give the viewer the ability to see the external part of the heart. A visual study of the human heart demonstrates the basic heartbeat mechanism. Utilizing images, heart sounds and 3D animation, patients may increase their knowledge of how the heart works in their body. All models were created according to the best data and available and with access to cadaver labs for the most realistic textures of the heart. Many of the tools with the latest rendering techniques had been implemented to achieve a more realistic and interest ing heartbeat animation. This medical animation depicts some heart related indications. Future versions of the animation could include showing blood flow in the chambers of a beating heart including the aortic and pulmonary valves. They can be viewed online as visual aids for teaching normal and abnormal cardiac function. The models depicting normal structure and function could be modified to illustrate various pathological conditions. This project is conducted as Engineer thesis in the field of Bio medical Engineering. extending out radially (5 cases), b) thick triangular cross-section c) a of both Two obscured three variants: (a) periodic sleep cycles with the sequences of phases: L, D, REM, W in each cycle, (b) a randomized distribution of phases, (c) the architecture based on our model. The results show that variant (c) gives 54% of the time series indistinguish able from real data using all standard linear and nonlinear HRV assessment methods (for variants (a) and (b) we obtain 24% and 6% accordingly). We hope that our model of sleep architecture will help in studies of healthy rest and will improve RR interval series modeling. 62 (2): 147–153. Background: Atrial fibrillation (AF) is the most complex and the most common sustained arrhythmia. The underlying pathophysi ological mechanisms of this arrhythmia are not fully understood and the complexity of atrial fibrillation remains described insuf -ficiently. Haissaguerre et al [1] demonstrated that arrhythmogenic focii within the pulmonary veins may initiate AF. However, the isolation of Pulmonary Veins during ablation procedure does not always lead to a cessation of atrial fibrillation and ablation of further sites is necessary. This complicates and lengthens the ablation procedure. The aim of assess reliability of the complexity analysis of a single electrogram as an estimator of the complex ity of the atrial fibrillation and as a predictor of the length of the ablation procedure necessary to end the arrhythmia. Methods: In the experimental left and right atrial endo cardial bipolar electrograms were recorded during ablation procedure of in patients. Patients to be in sustained AF prior to ablation with AF terminating during ablation. 5 sec ond electrogram samples were measured at baseline, post site (LPV, roof, CFAE etc.) and prior to termination. A total of 101 recordings examined. For all electrograms, algorithmic complexity calculated based on To check the significance of the results, ANOVA variance analysis, ROC analysis and Wilcoxon signed-rank tests were performed.Results: For the patients, who underwent only one ablation stage, the electrograms had a significantly lower algorithmic complex 29 presentation and record of obtained biomedical data. Additional functionality is automatic notification of emergency service in case of health risk detection. Information is sent in form of text message containing reason of notification with current patient’s location. Scope of the thesis includes also researches about project innovation, ef ficiency of created algorithms, possibilities of implementation and further system development using available technology. This project is conducted as Master thesis in the field of Electronics.