Miracle-dz/UniFAR-FTUs huggingface dataset:
Plant functional types in Earth System

Dynamic vegetation models use plant functional types (PFTs) to represent structural and functional variables that control energy, carbon, nutrient and water budgets. Wullschlegeret al. (pp. 1–16) review the origins of the PFT concept and address the current state of models that use PFTs in northern high-latitude ecosystems. They conclude that while the PFT concept is a valuable tool for reducing complexity in nature, additional attention should be devoted to remote sensing and mapping of vegetation, to trait database development for aboveand below-ground (i.e. root) processes, and to the replacement of fixed parameters for PFTs with formulations based on trait co-variance and empirical trait– environment relationships.
Note sur les $Q$-matrices d'Edmonds

When we want to solve Linear Programming Problems with integer or rationnal entries, and, in each case, to certify the result, classical floating point calculations are not allowed. We should work with Long Integers. Recently, Jack Edmonds [3] introduced a new tableau called Q-matrix which update is easy. We revisit these in term of the inverse of the basis. These calculations can be also used to give a rational representation of the inverse of a given integer matrix.
INFLUENCE OF ORGANIC FERTILIZERS ON GROWTH OF COCKSCOMB ( Celosia plumosa (Voss) Burv.) CONTEMPORARY AGRICULTURE SAVREMENA POLJOPRIVREDA

Summary: The work examined the influence of two organic fertilizers on growth and flowering of plumed cockscomb(Celosia plumosa (Voss) Burv. ). Two commercially available organic fertilizers, ‘Slavol’ and ‘Ecobooster 2’ were used. Plants of plumed cockscomb were produced in polystyrene containers. The investigation was conducted in a field experiment laid out in a randomized complete block design with three replicate plants per treatment. During production fertilizers were applied in the prescribed dosage every seven days. The results showed that ‘Slavol’ had positive influence on plant high, leaf width and length and on flower characteristics.
Information Seeking Behavior about Cancer and Associated Factors among Students at DebreTabor University, Ethiopia, 2019: Cross sectional study CURRENT STATUS: POSTED

Introduction The prevalence of cancer has been increasing and it is among the leading cause of death in Africa the last few years which mainly influnced by life-style. Understanding the information seeking behavior of individuals, especially Students who are more likely to seek health information than other people, can be seen as an opportunity to provide resources to improve lifestyle or prevent possible health threatening behaviors among students. The main objective of this study is to determine the health information seeking about cancer among students of Debretabor University Ethiopia. Objective The aim of this study was to assess cancer information seeking behavior (CISB) and its associated factors among students in Debre Tabor University. Methods Institutional based cross-sectional study design was conducted from March 01-30/2019. A total of 844 students were selected using multistage stratified sampling technique. Data entry and analyses were done using Epi info version 7.2 and SPSS version 20 respectively. Descriptive statistics and multivariate logistic regression analyses were applied to determine proportion of cancer information seeking behavior and to identify factors associated.
2,4,6-TRINITROBENZENESULFONIC ACID-INDUCED COLITIS IN Rattus : A CATEGORIZATION PROPOSAL CATEGORIZATION OF TNBS-INDUCED COLITIS

Reproducibility in animal research is crucial for its reliance and translational relevance. 27 The 2,4,6-trinitrobenzene sulfonic acid (TNBS)-induced model of inflammatory bowel 28 disease (IBD) is widely used but inconsistently and incompletely characterized 29 throughout the literature. This hinders comparisons between studies and influences the 30 low rate of translation of effective preclinical molecules. The purpose of this study was 31 to categorize TNBS-induced colitis, based on macroscopic and microscopic scoring 32 systems, and to identify basic routine parameters that could anticipate those categories. 33 We retrospectively analysed male Wistar Rattus norvegicus (n=28 for the control group 34 and n=87 for the TNBS group) and categorized TNBS-induced colitis in three 35 phenotypes: Mild, Moderate and Severe colitis, as for human IBD. Also, we showed that 36 the time course of food intake and fecal excretion (but not body weight, fluid intake or 37 welfare scores) could foresee those categories. So, routine evaluation of food intake and 38 fecal excretion may guide researchers in planning their experiments, selecting the animals 39 with the severity of colitis that better matches their aims, or applying early humane 40 endpoints to animals that will not be used in the experiments. 41 In conclusion, categorizing TNBS-induced colitis enhances the reproducibility of data 42 gathered with this experimental model and strengths its translational relevance. 43
Quantum lattice dynamical effects on single-particle excitations in one-dimensional Mott and Peierls insulators

As a generic model describing quasi-one-dimensional Mott and Peierls insulators, we investigate the Holstein-Hubbard model for half-filled bands using numerical techniques. Combining Lanczos diagonalization with Chebyshev moment expansion we calculate exactly the photoemission and inverse photoemission spectra, and use these to establish the phase diagram of the model. While polaronic features emerge only at strong electron-phonon couplings, pronounced phonon signatures, such as multiquanta band states, can be found in the Mott insulating regime as well. In order to corroborate the Mott to Peierls transition scenario, we determine the spin- and charge-excitation gaps by a finite-size scaling analysis based on density-matrix renormalization-group calculations.
prepuber-Mechanisms of action of the soy isoflavone genistein: emerging role for its effects via transforming growth factor (cid:98) signaling pathways 1–3

The soy isoflavone genistein attenuates growth factor– and cytokine-stimulated proliferation of both normal and cancer cells. This article reviews our current understanding of the potential mechanisms of action of genistein. In membrane preparations from mammalian cells, genistein is a potent and specific inhibitor of tyrosine autophosphorylation of the epidermal growth factor (EGF) receptor. However, in several cell systems in which it inhibits growth, genistein does not alter tyrosine phosphorylation of the EGF receptor or other tyrosine kinase substrates thought to be involved in signal transduction pathways, suggesting that other mechanisms may be responsible for its action. Alternatives include inhibition of DNA topoisomerase II activity, regulation of cell cycle checkpoints, and antiangiogenic and antioxidant activity. Experiments in our laboratory suggest a new concept, that genistein may inhibit cell growth by modulating transforming growth factor (TGF) (cid:98) 1 signaling pathways. Such a link between genistein action and TGF (cid:98) 1 function is supported by preliminary results of studies in patients with hereditary hemorrhagic telangiectasia (a genetic disorder involving mutations in proteins that regulate TGF (cid:98) receptor complex formation and signaling) in which several patients had dramatic attenuation of their symptoms after 1 wk of ingesting soy-based beverages. These preclinical studies in combination with our cell culture data suggest that the mechanism of genistein involves, if not requires, TGF (cid:98) 1-signaling.
Cost Efficient Resource Scheduling in Cloud Computing: a Survey

Resource scheduling is a tricky task in cloud environment. QoS is the main parameter from user’s perspective for Resource scheduling, while in parallel with this task, profit is very important parameter from point of view of cloud provider. The cloud service platform controls the revenue under particular market needs. The consumer get puzzled with many cloud suppliers for storing their data because various suppliers’ varying pricing scheme. In particular, recently many studies have paying attention on shaping the bond between server-side system facts and performance experience for dropping resource wastage. The main aim of cloud supplier is to provide utmost resource usage and profit, while also decreasing the energy and cost. The user wants higher throughput and less response time. Allocating proper resources with least overhead and full resource utilization is the objective of cloud. The service requests are generated by various users in cloud. Hence proper scheduling of resources is required for better performance of system and less operative cost.
A uniform assessment of an eﬀect of medicinal plants using a combination of RNA-seq experiments and text mining of biomedical bibliographies

BACKGROUND An eﬃciency if herbal medicine is possibly underestimated due to confusions in a choice between multiple approaches and terminologies. The availability of RNA seq experiments together with a volume if scienti(cid:12)c publications related to medicinal plants makes it possible to develop a framework for a uniform assess of an expected eﬀect of medicinal plants on a particular disease. METHODS Text mining of biomedical bibliographies was used to associate medicinal plants with a regulation of some genes in human genome. Publicly available RNA seq experiments were processed to determine changes in gene expression for some of human diseases. Grouping of genes and reduction of expression pro(cid:12)les within each group was used to bind changes in genes for a medicinal plant with an overall changes of expression in a state of a disease. RESULTS The tables of an expected eﬀect are provided for above 500 medicinal plants applied to the processed series of RNA-seq experiments. A model of coronavirus infection is presented as a case study for possible interpretation of the provided estimates.
Identiﬁcation of Residues outside of the Receptor Binding Domain That Inﬂuence the Infectivity and Tropism of Porcine Endogenous Retrovirus (cid:1)

Identiﬁcation of determinants of human tropism of porcine endogenous retrovirus (PERV) is critical to understanding the risk of transmission of PERV to recipients of porcine xenotransplantation products. Previously, we showed that a chimeric envelope cDNA encoding the 360 N-terminal residues of the human-tropic PERV envelope class A (PERV-A) SU and the 130 C-terminal residues of the pig-tropic PERV-C SU and all of TM (PERV-A/C) showed a 100-fold decrease in infectivity titer on human cells (M. Gemeniano, O. Mpanju, D. R. M. V. Eiden, and C. A. Wilson, Virology 346:108-117, 2006). To identify residues important for human cell infection, we performed site-directed mutagenesis on each of the nine residues, singly or in combination, that distinguish the C-terminal region of PERV-C from PERV-A. Of the nine amino acids, two single-amino-acid substitutions, Q374R and I412V, restored the infectivity of human cells to the chimeric PERV-A/C to a titer equivalent to that of PERV-A. In contrast, PERV-A/C mutant envelope Q439P resulted in undetectable infection of human cells and an approximately 1,000-fold decrease in control pig cells. Mutation of K441R rescued mutants that carried Q439P, suggesting an incompatibility between the proline residue at this position and the presence of KK in the proteolytic cleavage signal. We conﬁrmed this incompatibility with vectors carrying PERV-A envelope mutant R462K that were also rendered noninfectious. Finally, tropism of vectors carrying PERV-C envelope mutants with only four amino acid changes in the C terminus of PERV-C envelope, NHRQ436YNRP plus K441R, was shifted to one similar to that of PERV-A. Our results show an important and previously unrecognized role for infectivity and tropism for residues at the C terminus of SU. Porcine xenotransplantation the of PERV SU-IgG fusion PERV SU-IgG for PERV-SU the immunoglobulin following SU- IgG into used plasmids SU-IgGs mutant PERV- A/C Combo3B, A/C-I412V) ApaI-NotI ApaI-SpeI IgG, ApaI (cid:2) 3 (cid:2) ends C PERV-C SU, respectively, amplify PCR, the PERV-A/C Combo4 plasmids. Conventional cloning ligate
Blockade of b -adrenergic receptors prevents amphetamine-induced behavioural sensitization in rats: a putative role of the bed nucleus of the stria terminalis

Recent ﬁndings have given evidence a role for noradrenergic transmission in the mechanisms underlying behavioural sensitization to psychostimulants. This work was undertaken to investigate the possible role of b -adrenergic receptors in amphetamine-induced behavioural sensitization in rats. Rats were sensitized by a single administration of amphetamine (1 mg/kg s.c.) and challenged with the same dose 7 d later. The b 1 / b 2 -adrenergic receptor antagonists timolol (10 mg/kg i.p.) and nadolol (10 mg/kg i.p.), which respectively cross or do not readily cross the blood–brain barrier, were injected prior to the ﬁrst or second amphetamine administration. Timolol, but not nadolol, prevented the initiation of behavioural sensitization without interfering with the expression of the sensitized response or the acute locomotor response to amphetamine. Since we found amphetamine-induced Fos-activated cells closely associated with dopamine b -hydroxylase immunoreactive varicosities in the bed nucleus of the stria terminalis (BNST), we investigated the eﬀect of a bilateral micro-injection of timolol into this nucleus. Similarly to systemic administration, intra-BNST timolol (2.5 m g/side) prevented the development of behavioural sensitization. These results suggest that central b -adrenergic receptors could speciﬁcally modulate early neuronal changes leading to the development of behavioural sensitization to psychostimulants, and that the BNST could be an important part of the brain circuitry involved in these long-term neuroadaptations.
Complete Genome Sequence of Uropathogenic Proteus mirabilis , a Master of both Adherence and Motility (cid:1) †

The gram-negative enteric bacterium Proteus mirabilis is a frequent cause of urinary tract infections in individuals with long-term indwelling catheters or with complicated urinary tracts (e.g., due to spinal cord injury or anatomic abnormality). P. mirabilis bacteriuria may lead to acute pyelonephritis, fever, and bacteremia. Most notoriously, this pathogen uses urease to catalyze the formation of kidney and bladder stones or to encrust or obstruct indwelling urinary catheters. Here we report the complete genome sequence of P. mirabilis HI4320, a representative strain cultured in our laboratory from the urine of a nursing home patient with a long-term ( > 30 days) indwelling urinary catheter. The genome is 4.063 Mb long and has a G (cid:1) C content of 38.88%. There is a single plasmid consisting of 36,289 nucleotides. Annotation of the genome identiﬁed 3,685 coding sequences and seven rRNA loci. Analysis of the sequence conﬁrmed the presence of previously identiﬁed virulence determinants, as well as a contiguous 54-kb ﬂagellar regulon and 17 types of ﬁmbriae. Genes encoding a potential type III secretion system were identiﬁed on a low-G (cid:1) C-content genomic island containing 24 intact genes that appear to encode all components necessary to assemble a type III secretion system needle complex. In addition, the P. mirabilis HI4320 genome possesses four tandem copies of the zapE metalloprotease gene, genes encoding six putative autotransporters, an extension of the atf ﬁmbrial operon to six genes, including an mrpJ homolog, and genes encoding at least ﬁve iron uptake mechanisms, two potential type IV secretion systems, and 16 two-component regulators.
Market integration of arecanut in Karnataka state: An error correction model approach

Arecanut, being an important commercial and plantation crop of Karnataka, its influence on state economy is significant and profound. To stabilize the vital arecanut economy in the state, government has to emphasize on both production and market related issues. But the existing government policies are favoring the production related aspects. While the existing fewer government policies related to marketing are devised devoid of information on market integration, which is unscientific. In order to formulate scientific policies in case of arecanut, consideration of market integration becomes imperative. In order to assess the existence of market integration in arecanut, data on monthly modal prices of arecanut was collected through Agmarknet from seven representative markets in Karnataka state. Cointegration and error correction model were employed to test the presence of market integration and the results of the study revealed that the arecanut markets in the state are integrated with high speed of adjustment. Thus, it can be concluded that integrated arecanut markets are efficient in price transmission. Hence, in order to stabilize arecanut economy government has to stabilize the prices in one important market, which will be transmitted to other markets automatically with a speed equal to coefficient of error correction, eventually reducing the cost of stabilization.
Orf 20 : MLKKTLAILGLSASLLFVSAHANAHTSRLTLDQTNELYTRLAAEGRGVDTDQVYGMQ : 57 Skl : MSKKQEMIQFFIDKANAGDGVDNDGAYGFQ : 30 PlyTW : MKTLKQAESYIKSKVNTGTDFDGLYGYQ : 28 LysWMY : MKTKAQAKSWINSKIGKGIDWDGMYGYQ : 28 Ply 187 : MALPKTGKPTAKQVVDWAINLIGSGVDVDGYYGRQ : 35 * Orf 20

Bacteriophage M102 is a lytic phage specific for serotype c strains of Streptococcus mutans, a causative agent of dental caries. In this study, the complete genome sequence of M102 was determined. The genome is 31,147 bp in size and contains 41 ORFs. Most of the ORFs encoding putative phage structural proteins show similarity to those from bacteriophages from Streptococcus thermophilus. Bioinformatic analysis indicated that the M102 genome contains an unusual lysis cassette, which encodes a holin and two lytic enzymes. R E S E A R C H L E T T E R GenomesequenceofStreptococcusmutans bacteriophageM102 Jan R. van der Ploeg Institute of Oral Biology, University of Zürich, Zürich, Switzerland Correspondence: Jan R. van der Ploeg, Institute of Oral Biology, University of Zürich, Plattenstrasse 11, CH-8032, Zürich, Switzerland. Tel. : 141 44 634 3329; fax: 141 44 634 4310; e-mail: jan.vanderploeg@zzmk.uzh. ch Received 4 May 2007; revised 3 July 2007; accepted 4 July 2007. First published online August 2007. DOI:10.1111/j.1574-6968.2007. 00873.x Editor: Oscar Kuipers
kinases and mRNA decapping machinery control root 9 development and response to salt

SNF1-RELATED PROTEIN KINASES 2 (SnRK2) are important components of early osmotic 39 and salt stress signaling pathways in plants. The Arabidopsis ( Arabidopsis thaliana ) SnRK2 40 family comprises the abscisic acid (ABA)-activated protein kinases SnRK2.2, SnRK2.3, 41 SnRK2.6, SnRK2.7, and SnRK2.8, and the ABA-independent subclass 1 protein kinases 42 SnRK2.1, SnRK2.4, SnRK2.5, SnRK2.9, and SnRK2.10. ABA-independent SnRK2s act at the 43 post-transcriptional level via phosphorylation of VARICOSE (VCS), a member of the mRNA 44 decapping complex, that catalyzes the first step of 5’mRNA decay. Here, we identified VCS and 45 VARICOSE RELATED (VCR) as interactors and phosphorylation targets of SnRK2.5, 46 SnRK2.6, and SnRK2.10. All three protein kinases phosphorylated Ser645 and Ser1156 of VCS, 47 while SnRK2.6 and SnRK2.10 also phosphorylated VCS Ser692 and Ser680 of VCR. We 48 showed that subclass 1 SnRK2s, VCS, and 5’ EXORIBONUCLEASE 4 (XRN4) are involved in 49 regulating root growth under control conditions as well as modulating root system architecture in 50 response to salt stress. Our results suggest interesting patterns of redundancy within subclass 1 51 SnRK2 protein kinases, with SnRK2.1, SnRK2.5 and SnRK2.9 controlling root growth under 52 non-stress conditions and SnRK2.4 and SnRK2.10 acting mostly in response to salinity. We 53 propose that subclass 1 SnRK2s function in root development under salt stress by affecting the 54 transcript levels of aquaporins, as well as CYP79B2, an enzyme involved in direct or indirect elongation via control of water fluxes primordia via local auxin biosynthesis. activity SNF1-related
Bæredygtig energiudvikling

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Identiﬁcation of Bacillus subtilis SipW as a Bifunctional Signal Peptidase That Controls Surface-Adhered Bioﬁlm Formation

Bioﬁlms of microbial cells encased in an exopolymeric matrix can form on solid surfaces, but how bacteria sense a solid surface and upregulate bioﬁlm genes is largely unknown. We investigated the role of the Bacillus subtilis signal peptidase, SipW, which has a unique role in forming bioﬁlms on a solid surface and is not required at an air-liquid interface. Surprisingly, we found that the signal peptidase activity of SipW was not required for solid-surface bioﬁlms. Furthermore, a SipW mutant protein was constructed that lacks the ability to form a solid-surface bioﬁlm but still retains signal peptidase activity. Through genetic and gene expression tests, the non-signal peptidase role of SipW was found to activate bioﬁlm matrix genes speciﬁcally when cells were on a solid surface. These data provide the ﬁrst evidence that a signal peptidase is bifunctional and that SipW has a regulatory role in addition to its role as a signal peptidase.
COMPARATIVE STUDY OF MODIFIED CENTRIFUGED BLOOD SMEAR, PERIPHERAL BLOOD SMEAR AND RAPID DIAGNOSTIC TEST METHODS IN THE DIAGNOSIS OF MALARIA INFECTION

The gold standard for malaria diagnosis is microscopy with peripheral blood smear (PBS). Rapid diagnostic test (RDT) is a substitute especially where trained personnels are not available. Adoption of methods which improve the accuracy of malaria diagnosis will reduce inappropriate use of new expensive antimalarial treatments. The aim of this study was to compare the modified centrifuged blood smear (MCBS) as an alternative and more sensitive technique in malaria diagnosis. Venous blood was collected from 140 symptomatic subjects and subjected to three techniques for the diagnosis of malaria; PBS examination, MCBS examination, and RDT (CareStart). The MCBS method detected infection in 40% of the subjects examined, followed by PBS (36%) and RDT (20%). MCBS had a sensitivity of 92% and specificity of 90%, while PBS recorded a sensitivity of 71.4%, specificity of 80%, PPV of 80% and NPV of 82%. RDT (CareStart) had a sensitivity of 43%, specificity of 95%, PPV of 85.7% and NPV of 91.4%. Addition of the centrifugation step in MCBS increased the sensitivity of the peripheral blood smear method from 71.2% to 92%, and also its specificity from 80% to 90%. This study has confirmed that MCBS is a more sensitive, easy to perform and affordable technique in the routine diagnosis of malaria.