Miracle-dz/UniFAR-FTUs huggingface dataset:
Computer Modelling of High Frequency Electromagnetic Field Penetration into the Human Head

Serious concern about the effect of radio waves on human health probably dates back to the end of the Second World War, when information on high-power radar transmitters was beginning to be declassified and it was noted that 'warming sensations' were experienced by personnel standing close to the transmitting antenna. The effect was exploited beneficially in medical hyperthermia and microwave ovens, but it was quite obvious that, at high levels of power dissipation, a human being could suffer serious injury through excessive heating. Investigations thus began to determine the maximum safe level ofpower flux density so that safety guidelines could be established. In recent years, international safety standards for electromagnetic radiation have tended to converge and there is now a small number of standards which command relatively wide international respect, although national authorities still tend to adopt slightly different standards, based on the researches of their own specialists. However, until concern about the effect of mobile telephones arose, most safety standards were drafted on the assumption that irradiation of the body would be from a relatively distant transmitter and hence essentially uniform. Thus nonuniformity was the particularly distinguishing feature which had to be addressed in attempting to assess safe working limits for the power radiated by such telephones. The general view was that evaluation of the detailed distribution of electromagnetic power dissipation in relevant parts of the human body was essential in order to quantify this effect accurately, and research into ways to achieve this was initiated in a number of countries. Uniform irradiation from a distant transmitter is quantified as an incident
Network Host Cardinality Estimation Based on Artificial Neural Network

Cardinality estimation plays an important role in network security. It is widely used in host cardinality calculation of high-speed network. However, the cardinality estimation algorithm itself is easy to be disturbed by random factors and produces estimation errors. How to eliminate the influence of these random factors is the key to further improving the accuracy of estimation. To solve the above problems, this paper proposes an algorithm that uses artificial neural network to predict the estimation bias and adjust the cardinality estimation value according to the prediction results. Based on the existing algorithms, the novel algorithm reduces the interference of random factors on the estimation results and improves the accuracy by adding the steps of cardinality estimation sampling, artificial neural network training, and error prediction. The experimental results show that, using the cardinality estimation algorithm proposed in this paper, the average absolute deviation of cardinality estimation can be reduced by more than 20%.
Expanding insurability through exploiting linear partial information

This contribution aims to expand insurability using partial linear information (LPI) on probabilities of the type, $ {r}_{1}\ge {r}_{3} $ (with $ {r}_{1}+{r}_{2}+{r}_{3}+\dots {r}_{n} = {1} $). LPI theory permits to exploit such weak information for systematic decision-making provided the decision-maker is willing to apply the maxEmin criterion in a game against Nature. The maxEmin rule is a natural generalization of expected profit (probabilities are known) and the maximin rule (probabilities are unknown). LPI theory is used to find out whether a crypto assets portfolio offered to an insurance company is insurable. In an example, an unfavorable future development of losses causes maximum expected loss to exceed the present value of premiums, rendering the portfolio uninsurable according to maxEmin. However, this changes when LPI concerning this development is available, while the integration of uncertain returns from investing the extra premium fails to achieve insurability in this example. Evidently, LPI theory enables insurers to accept risks that otherwise are deemed uninsurable.
Plastid redox state and sugars as interactive regulators of nuclear photosynthetic gene expression

Feedback control of photosynthesis by carbon metabolites has long been recognised but the underlying cellular mechanisms that regulate this process remain unclear. As part of this thesis project it was demonstrated that in an Arabidopsis cell culture a block in photosynthetic electron flux prevents the increase in transcript levels of chlorophyll a/b binding protein (CAB) and the small subunit of Rubisco (RBCS) that typically occurs when intracellular sugar levels are depleted. In contrast, the expression of the nitrate reductase (NR) gene, which is induced by sugars, was not changed. These findings were confirmed in planta using Arabidopsis carrying the firefly luciferase reporter gene (LUC) fused to the plastocyanin (PC) and CAB2 photosynthetic gene promoters. Transcription from both promoters increased upon carbohydrate deprivation. Blocking photosynthetic electron transport with 3-(3',4'-dichlorophenyl)-1,1'-dimethylurea (DCMU) prevented this increase in transcription. This work led to the conclusion that plastid derived redox signalling can over-ride the sugar regulated expression of nuclear encoded photosynthetic genes. In the sugar response mutant sun6 (sucrose uncoupled) PC-LUC transcription actually increased in response to exogenous sucrose rather than decreasing as in the wild type. Interestingly, plastid derived redox signals do not influence this defective pattern of sugar regulated gene expression in the sun6 mutant. A model, which invokes a positive inducer originating from the photosynthetic electron transport chain, was proposed to explain the nature of the plastid-derived signal. Previous studies in algal systems have shown that light and temperature are critical regulators of plastid redox state. When the redox state of the photosynthetic electron transport chain in the Arabidopsis culture was altered by changing temperature and light conditions differential effects were observed in carbon starved and carbon supplied cells. These results confirm that various environmental parameters can affect the plastid redox state and consequently nuclear gene expression in higher plants. Over the last few years a growing number of plant 14-3-3 binding proteins, including DNA binding proteins and key proteins of carbon metabolism, have been identified. The binding of these proteins to 14-3-3 proteins affects their phosphorylation state and consequently cellular activity. Sugar deprivation has recently been shown to have a dramatic effect on 14-3-3 binding protein abundance in the same cell culture that was used in this thesis work. However, the plastid redox signal as identified in this thesis work did not result in an altered regulation of 14-3-3 binding proteins by sugars, providing evidence that at least this proposed part of the sugar signalling pathway is not regulated by the redox state of the plastid.
The Impact of Electronic Word of Mouth and Brand Image on Online Purchase Decisions Moderated by Price Discount

This study aims to analyze the impact of electronic word of mouth and brand image on online purchasing decisions moderated by price discounts. This study uses a quantitative research paradigm with an explanatory approach. The research instrument is a questionnaire designed to measure electronic word of mouth, brand image, price discount, and online purchase decisions. Data were collected from primary sources through surveys. The survey, as a data collection technique, was carried out in Malang City. Partial distribution of the questionnaire used google form and distributed directly to respondents. The research object is the Shopee platform, while the research subjects are millennials who have used the Shopee platform in the past year. The total number of respondents involved in this study was 100. Data analysis used two approaches namely categorization index analysis and multivariate regression. Study results show that electronic word of mouth is in a reasonably low category. The brand image has a high category, while the price discount has a reasonably high category. Hypothetically tested, electronic word mouth has no impact on purchasing decisions. However, when moderated by a price discount, it has an impact on purchasing decisions. Meanwhile, whether moderated by price discounts or not, the brand image variable had an impact on online purchasing decisions on the Shopee platform.
Epistemic in/justice: Towards ‘Other’ ways of knowing

This paper brings a critical awareness to the interrelations between epistemic injustice and knowledge hierarchies, through an insufficient attention to the Other as epistemically harmed. Because of the dominant empirical and theoretical authority Others are subjected to in research practices and dissemination, our paper explores how marginalised voices possess less epistemic agency due to their disciplining, neglect and subjugation as knowers through testimonial and hermeneutical injustice. We contribute two new categories of epistemic injustice in marketing; Silencing and Ignorance; areas, which reproduce and reify knowledge hierarchies but equally provide scholars with an opportunity to contest epistemic dominance. Through an explicit acknowledgement of the relationship between difference, power and knowledge in meaning-making, we argue for Other consciousness which entails (i) privileging Othered knowledge, (ii) highlighting structural epistemic in/justice within Marketing academe and (iii) advocating for artistic-inclusive processes, to alter how we theorise knowing Others, and Other knowers, in marketing scholarship.
Lp(a) and the Risk for Cardiovascular Disease: Focus on the Lp(a) Paradox in Diabetes Mellitus

Lipoprotein(a) (Lp(a)) is one of the strongest causal risk factors of atherosclerotic disease. It is rich in cholesteryl ester and composed of apolipoprotein B and apo(a). Plasma Lp(a) levels are determined by apo(a) transcriptional activity driven by a direct repeat (DR) response element in the apo(a) promoter under the control of (HNF)4α Farnesoid-X receptor (FXR) ligands play a key role in the downregulation of APOA expression. In vitro studies on the catabolism of Lp(a) have revealed that Lp(a) binds to several specific lipoprotein receptors; however, their in vivo role remains elusive. There are more than 1000 publications on the role of diabetes mellitus (DM) in Lp(a) metabolism; however, the data is often inconsistent and confusing. In patients suffering from Type-I diabetes mellitus (T1DM), provided they are metabolically well-controlled, Lp(a) plasma concentrations are directly comparable to healthy individuals. In contrast, there exists a paradox in T2DM patients, as many of these patients have reduced Lp(a) levels; however, they are still at an increased cardiovascular risk. The Lp(a) lowering mechanism observed in T2DM patients is most probably caused by mutations in the mature-onset diabetes of the young (MODY) gene and possibly other polymorphisms in key transcription factors of the apolipoprotein (a) gene (APOA).
Towards a clinically practical brain-computer interface

Nearly two million people in the United States have degenerative diseases that impair the neural pathways that control muscles. The most severely affected people lose all voluntary muscle control and become completely "locked in" to their bodies, unable to communicate in any way. Brain-computer interfaces (BCIs) can allow these individuals to communicate again by creating a new communication channel directly from the brain to an output device. Recent studies have shown that BCI technology can allow paralyzed people to share their intent with others, and thereby demonstrate that direct communication from the brain to the external world is possible and that it might serve useful functions. While these technical demonstrations are encouraging, practical applications of BCI technology to the needs of people with severe disabilities are significantly impeded primarily by three issues. These are the limitations of current sensor technologies, the requirements implied by traditional signal processing approaches, and the non-intuitive tasks that have been used for BCI communication. Mainly due to these three issues have current BCI systems produced impressive laboratory demonstrations but no device of appreciable clinical value. This dissertation set out to address these problems to work towards a BCI system that can leave the confines of laboratory research to address the actual communication and control needs of the severely paralyzed. The principal results demonstrate that the use of sensors placed on the surface of the brain has favorable characteristics compared to existing non-invasive and highly invasive sensors, that application of a novel signal processing procedure can reduce the substantial expert supervision that is currently required, and disprove the widespread assumption that the use of intuitive tasks requires electrodes that are implanted within the brain. In summary, the results presented in this dissertation encompass three advances that are critical to the successful translation of brain-computer interface from their current state of primarily laboratory demonstrations into clinically practical communication and control devices for the paralyzed.
A site-differentiated [4Fe–4S] cluster controls electron transfer reactivity of Clostridium acetobutylicum [FeFe]-hydrogenase I

One of the many functions of reduction–oxidation (redox) cofactors is to mediate electron transfer in biological enzymes catalyzing redox-based chemical transformation reactions. There are numerous examples of enzymes that utilize redox cofactors to form electron transfer relays to connect catalytic sites to external electron donors and acceptors. The compositions of relays are diverse and tune transfer thermodynamics and kinetics towards the chemical reactivity of the enzyme. Diversity in relay design is exemplified among different members of hydrogenases, enzymes which catalyze reversible H2 activation, which also couple to diverse types of donor and acceptor molecules. The [FeFe]-hydrogenase I from Clostridium acetobutylicum (CaI) is a member of a large family of structurally related enzymes where interfacial electron transfer is mediated by a terminal, non-canonical, His-coordinated, [4Fe–4S] cluster. The function of His coordination was examined by comparing the biophysical properties and reactivity to a Cys substituted variant of CaI. This demonstrated that His coordination strongly affected the distal [4Fe–4S] cluster spin state, spin pairing, and spatial orientations of molecular orbitals, with a minor effect on reduction potential. The deviations in these properties by substituting His for Cys in CaI, correlated with pronounced changes in electron transfer and reactivity with the native electron donor–acceptor ferredoxin. The results demonstrate that differential coordination of the surface localized [4Fe–4S]His cluster in CaI is utilized to control intermolecular and intramolecular electron transfer where His coordination creates a physical and electronic environment that enables facile electron exchange between electron carrier molecules and the iron–sulfur cluster relay for coupling to reversible H2 activation at the catalytic site.
Open source software in life science research

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The Importance of Recognizing Social Contexts in Research on Bilingualism

In their recent keynote, Titone and Tiv (2022) make a call for scientists to consider bilingualism in the social contexts where languages are used. Situated in multilingual Montréal and bringing unique positionalities, Titone and Tiv have provided converging perspectives that cognitive and linguistic behavior is symbiotic. The biological reference is intentional, referring to both the individual and her environment to be living and interactional. Beyond the methodological and analytical recommendations addressed in the keynote, we intend to reinforce this position with two points: (1) bilingual experience is interactional; and (2) outcomes when comparing monolinguals to bilinguals will vary across contexts. This latter argument has implications for replicability.
Roles of Oxidative Stress in Acute Tendon Injury and Degenerative Tendinopathy—A Target for Intervention

Both acute and chronic tendon injuries are disabling sports medicine problems with no effective treatment at present. Sustained oxidative stress has been suggested as the major factor contributing to fibrosis and adhesion after acute tendon injury as well as pathological changes of degenerative tendinopathy. Numerous in vitro and in vivo studies have shown that the inhibition of oxidative stress can promote the tenogenic differentiation of tendon stem/progenitor cells, reduce tissue fibrosis and augment tendon repair. This review aims to systematically review the literature and summarize the clinical and pre-clinical evidence about the potential relationship of oxidative stress and tendon disorders. The literature in PubMed was searched using appropriate keywords. A total of 81 original pre-clinical and clinical articles directly related to the effects of oxidative stress and the activators or inhibitors of oxidative stress on the tendon were reviewed and included in this review article. The potential sources and mechanisms of oxidative stress in these debilitating tendon disorders is summarized. The anti-oxidative therapies that have been examined in the clinical and pre-clinical settings to reduce tendon fibrosis and adhesion or promote healing in tendinopathy are reviewed. The future research direction is also discussed.
Effect of probiotic and Moringa oleifera extract on performance, carcass yield, and mortality of Peking duck

Background and Aim: Antibiotics have been used as growth promoters in poultry. However, continuous and long-term antibiotics can cause resistance, suppress the immune system, and accumulate toxic residue. To overcome these problems, feed additives that are safe for livestock and health for humans are needed, including probiotics. Therefore, the study aimed to determine the effect of probiotics (Lactobacillus acidophilus, Lactobacillus casei, Lactobacillus lactis, and Bifidobacterium spp.) and Moringa oleifera extract on performance (body weight gain, body weight, feed intake, feed efficiency, and feed conversion ratio [FCR]), carcass yield (carcass weight and percentage of carcass) and mortality of Peking duck. Materials and Methods: This study used 48 Peking ducks, divided into four treatments and six replications. Each replication consisted of two ducks. The treatments were as follows: T0=control, T1=4 mL containing 1.2×108 CFU/mL of probiotic in drinking water, T2=4 mL containing M. oleifera extract in drinking water, and T3=2 mL containing 1.2×108 CFU/mL of probiotic in drinking water+2 mL containing M. oleifera extract in drinking water. The probiotics consist of L. acidophilus, L. casei, L. lactis, and Bifidobacterium spp. The data were statistically analyzed through analysis of variance. For the follow-up test, a multiple range test was conducted. Results: There was no significant difference (p>0.05) between body weight, feed intake, and mortality treatments. By contrast, control and treatment showed a significant difference (p<0.05) on feed efficiency, FCR, body weight gain, carcass weight, and percentage of carcass weight. Results of body weight gain statistics showed no significant difference (p>0.05) between T0 and T1, but T0 and T1 showed a significant difference with T2 and T3. The results of the feed efficiency statistic showed no significant difference (p>0.05) between T0, T1, and T2, but there was a significant difference between T0, T1, and T3. Feed efficiency at T2 showed no significant difference with T3, T1, and T0. The results of the FCR statistic showed no significant difference (p>0.05) between T0, T1, and T2, but there was a significant difference between T0, T1, and T3. FCR at T2 showed no significant difference with T3, T1, and T0. The carcass weight statistic showed no significant difference (p>0.05) between T0, T1, and T3, but there was a significant difference between T0 and T2. T2 showed no significant difference with T1 and T3. The carcass percentage statistic showed no significant difference (p>0.05) between T0 and T1, but T0 and T1 showed a significant difference (p<0.05) with T2 and T3. Conclusion: Based on the study results, it can be concluded that the use of a combination of probiotics (L. acidophilus, L. casei, L. lactis, and Bifidobacterium spp.) and M. oleifera extract can increase the production performance of Peking ducks and is safe for ducks’ health.
Fabrication of a 3D carbon electrode for potential dielectrophoresis-based hepatic cell patterning application using carbon micro-electrical-mechanical system (CMEMS)

Cell patterning of hepatocyte cells is one of the techniques to construct liver tissue engineering. This work presents the development of a 3D carbon dielectrophoresis (carbonDEP) microfluidic chip for cell patterning using carbon micro-electrical-mechanical system microfabrication approach. The new design of electrode named interdigitated radiating-strips electrode (IRSE) was fabricated to generate positive DEP (pDEP) force for cell patterning mimicking the biological hepatic lobule. The electrical characterization of the fabricated carbon electrode shows that the average electrode resistivity is 4.61 ± 1.19 × 10−4 Ω m which is low enough to generate effective DEP force using 10 of volts. Results also show the shrinkage of the SU-8 structures during pyrolysis which gives impact to the final dimension of the carbon electrode. The functioning of the DEP microfluidic chip was demonstrated through DEP polystyrene microbeads patterning as a model of hepatocyte cells. 3D carbon IRSE presents a 67% increase in trapping efficiency of pDEP microbeads as compared to the planar carbon IRSE and the microbeads were pattern along the electrical field induced to form a hepatic lobule mimicking pattern. These results suggest that the 3D carbonDEP microfluidic chip has a great potential to be used for 3D hepatic cells patterning for liver tissue engineering applications.
Earthquake Considerations in Earth Dam Design

In 1963, the writer was engaged by the State of California Department of Water Resources to make a study of the influence of the hazard of earthquakes on the design of embankment type dams. The purpose of the study was to scrutinize the information available to aid the civil engineer in answering the basic question How should earth dams be designed differently in regions of earthqyake activity? This paper summarizes some of the main conclusions of the study.