Miracle-dz/UniFAR-FTUs huggingface dataset:
A Rigid Dual Phase Control Approach for Online Cloud Computing Services

: We offer a completely new access control system (2-FA) and two-factor authentication for cloud-based cloud services. Specifically, under the access control system we use from two FA modules, access control features are implemented with a person's secret key and a lightweight security device. Because the user cannot connect somewhere when they do not have a connection, the machine can improve peace of mind on the device, especially in individual scenarios where many users share the exact same computer for cloud-based services. There are two issues with your account / password system. First, traditional account / password-based authentication is not based on maintaining privacy. Under the signature or understanding formula, take the main factor along with the SEM together. In addition, object-based control within the system also allows the cloud server to restrict the use of individual users with the same number of features while maintaining user privacy, meaning that the cloud server understands only that the client complies with the correct document, but does not work. The minute inside the user. Under Validate Signature or Encryption Format, the client's public key takes the corresponding identity. Finally, we implemented a simulation to demonstrate practical capability within our proposed dual system.
Thymocyte Contact or Monoclonal Antibody-Mediated Clustering of (cid:97) 3 (cid:98) 1 or (cid:97) 6 (cid:98) 4 Integrins Activate Interleukin-6 (IL-6) Transcription Factors (NF- (cid:107) B and NF-IL6) and IL-6 Production in Human Thymic Epithelial Cells

T-cell precursors develop within the thymus in contact with multiple supportive elements, among which thymic epithelial cells (TEC) are known to exert a dominant role in their homing, survival, and functional differentiation. All these functions are supported by cell-cell contacts and cytokine release. Signaling events triggered in lymphoid cells by adhesion to TEC are well characterized, but little is known about the opposite phenomenon. To address this issue, we derived cultures of TEC from human normal thymus. TEC monolayers were cocultured with thymocytes and immuno-stained with monoclonal antibodies (MoAbs) to integrin (cid:97) ( (cid:97) 2, (cid:97) 3, (cid:97) 4, and (cid:97) 6) and (cid:98) ( (cid:98) 1 and (cid:98) 4) chains. Optical and confocal analysis showed that integrins were polarized on TEC at discrete surface locations: (cid:97) 6 (cid:98) 4 lined the basal surface of TEC monolayers, whereas (cid:97) 3 (cid:98) 1 was found mostly at TEC-TEC contacts; it is noteworthy that both (cid:97) 3 (cid:98) 1 and (cid:97) 6 (cid:98) 4 became highly enriched also at the boundaries with adherent thymocytes. Functional studies performed with MoAbs anti- (cid:98) 1 and - (cid:98) 4 integrins showed that (cid:98) 1, and, to a much lower extent, (cid:98) 4 heterodimers are involved in the TEC-thymocyte adhesion. Thymocyte contact or MoAb- mediated ligation of (cid:97) 3, (cid:97) 6, (cid:98) 1, and (cid:98) 4 integrins was investigated as a potential inducer of intracellular signaling in TEC. Thymocyte adhesion or cross-linking of MoAbs bound to integrins clustered at the TEC/thymocyte contact sites led to activation of interleukin-6 (IL-6) gene transcription factors, namely NF-IL6 serine phosphorylation and NF- (cid:107) B nuclear targeting, as well as to increased IL-6 secretion. We propose that integrin clustering occurring during TEC-thymocyte contacts modulates in TEC the gene expression of a cytokine involved in thymocyte growth and functional differentiation.
Is cell size a spandrel? The Harvard community has made this article openly available. Please share how this access benefits you. Your story matters

All organisms control the size of their cells. We focus here on the question of size regulation in bacteria, and suggest that the quantitative laws governing cell size and its dependence on growth rate may arise as byproducts of a regulatory mechanism which evolved to support multiple DNA replication forks. In particular, we show that the increase of bacterial cell size during Lenski’s long-term evolution experiments is a natural outcome of this proposal. This suggests that, in the context of evolution, cell size may be a ’spandrel’ The question of how cells control their sizes has a long history ( 1926 The observation that cells of a given type often have a narrow size distribution suggests that cell size is tightly controlled, and one can try to rationalize this observation in various ways ; For instance, one may speculate that diffusion will limit the supply of nutrients in large cells due to their small surface-area-to-volume ratio: however, many microbes are order of magnitudes smaller than any limit imposed by diffusion ( Landy, 2014 ). Here I discuss the control of cell size in bacteria, which has been shown to manifest several size-related quantitative laws.
Some elliptic problems with singularities

In this dissertation, we first study removable singularity results for second order elliptic PDEs, the model case being the following : −∆u + cu ≥ f in Ω\K, with u ≥ 0 and cap2 (K) = 0. We also prove a strong maximum principle for the operator −∆ + a(x), with a potential a ∈ L. These results rely on some variants of the standard Kato’s inequality. We next present an estimate in the spirit of Poincaré’s inequality. The motivation for our result comes from a new characterization of the Sobolev spaces. We also study topological singularities of maps g ∈ W (S;S) ; we compute, for instance, the relaxed energy and the total variation of the Jacobian of g. Finally, we consider several properties of the distributions of the form ∑ j (δpj − δnj), defined on a complete metric space.
Risk-benefit analysis of altering BCG vaccination from birth to 6 weeks of age

Thus if the risk of these complications is one-third less in the half of infants vaccinated at 6 weeks we would expect to save 1 case of BCG abscess formation, 0.1 cases of supurative lymphadenitis and 0.03 cases of osteomyelitis. Although small in real numbers, it should be noted that the estimated reduction in BCG induced complications in our study is higher than the estimated risk of acquiring latent or active TB (see below).
Work-in-Progress: Online Tutorials to Help Undergraduates Bridge the Gap Between General Writing and Engineering Writing

Although engineering students are regularly called upon to write as engineers in design courses, laboratory courses, and internships throughout their curriculum, many engineering students do not formally learn to write as an engineer until their third or fourth year of study. For this reason, a gap exists between what engineering students know about general writing and how they are expected to write as an engineer. As a first step to address this gap, this paper addressed the research questions of whether the following two tutorials can help teach younger engineering students the differences between general writing and engineering writing: This paper presents our development of these resources and their inclusion in a larger set of online resources that we have established: Although our online resources are no substitute for a full-fledged course on engineering communication, our overall finding is that these resources are helping students learn to write and present as engineers and scientists in design courses, laboratory courses, and professional development workshops across the United States. From September 2019 through April 2020, these resources received more than 39,000 film views.
Institutional Knowledge at Singapore Management University Inefficient Worker Turnover

This paper considers the e ﬃ ciency properties of risk-neutral workers’ mobility decisions in an equilibrium model with search frictions, but no search externalities, when the rent accruing to a match is split through bargaining. Matches are ex ante homoge-neous and their true productivity is learnt after the match is formed. It is shown that the e ﬃ ciency of worker turnover depends on contract enforceability, and that in the absence of complete enforceability the equilibrium fails to be e ﬃ cient. This is because without complete enforceability ﬁ rms cannot credibly o ﬀ er workers contracts that will guarantee them the entire future of all potential future matches. Empirical studies often de ﬁ ne worker turnover as worker turnover for a given period at a given establishment is the sum of the number of accessions and separations from the beginning to the end of the period. And aggregate worker turnover is the sum of worker turnover over all establishments. in contact with two ﬁ rms. However, the results of Cahuc, Postel-Vinay and Robin suggest that this competition e ﬀ ect is important, and that it can be responsible for between 40 to 100 per cent of wage increase for some groups of workers.
Institutional Knowledge at Singapore Management University Differences in the reliability of fair value hierarchy measurements: A cross country study

Prior research suggests that there are significant differences in how investors perceive the reliability of fair values across the fair value hierarchy. An unaddressed question in this stream of research is whether cross-country differences in institutional factors are able to mediate differences in reliability for the fair value hierarchy measurements. Based on an international sample of banks across 20 different countries, we find that the probability of crash risk is lower among countries with better financial development infrastructure, greater level of trust, tighter security regulations and higher level of disclosure requirements. These results apply to Level 1 assets but not to Level 2 and Level 3 assets. We also document that these cross-country factors improve the trading volume of our sample banks. Our study suggests that while ongoing concerns toward the more opaque fair values are not fully eliminated by institutional differences, they matter in influencing investor willingness to trade in these stocks.
Busy period, virtual waiting time and number of customers in G (delta)

[Kadankov, Victor] Ukrainian Natl Acad Sci, Inst Math, UA-01601 Kiev 4, Ukraine. [Kadankova, Tetyana] Hasselt Univ, Ctr Stat, B-3590 Diepenbeek, Belgium. kadankov@voliacable.com; tetyana.kadankova@uhasselt.be
ARROW@TU Dublin ARROW@TU Dublin Developing Subsidiary Contribution to the MNC-Subsidiary Developing Subsidiary Contribution to the MNC-Subsidiary Entrepreneurship and Strategy Creativity Entrepreneurship and Strategy Creativity

15 Despite its theoretical and managerial significance, subsidiary entrepreneurship and its effects 16 on subsidiary contribution remain underexplored in the literature. We propose that subsidiary 17 entrepreneurship encourages more creative strategic responses to escalating environmental 18 change. We explore the direct and mediating effects of subsidiary entrepreneurship on 19 subsidiary contribution to the MNC, particularly subsidiary strategy creativity. We use 20 structural equation modelling to test our propositions on data generated from surveying the 21 population of Irish subsidiaries of foreign MNCs, and find strong support for our theoretical 22 predictions. The managerial implications of subsidiary entrepreneurship in generating creative 23 strategy, prompting strategic initiatives and improving performance are discussed.
Awareness Implications on Adverse Drug Reactions: Findings from A Cross-Sectional Study among Outpatients Attending a Public Hospital in Malaysia

Introduction: Adverse drug reactions (ADRs) is a growing concern worldwide as the risk of the ADR is underrated. Spontaneous or voluntary reporting of suspected adverse drug reactions (ADRs) provides input for medication without harm initiatives as to reduce medication related adversities. Objectives: To assess the knowledge, beliefs, and behaviour of outpatients and its association in addressing adverse drug reactions. Methods: A cross-sectional study was conducted among voluntary participation of 400 outpatients attending Penang General Hospital, Malaysia. The targeted respondents were long-term medications dependant, whom was waiting for their prescriptions at the department of pharmacy. Results: There was a significant difference between knowledge and attitude in addressing ADRs (p<0.05) among the respondents. Respondents agreed that western medicine solely causes side effects (84.5%). In addition, doctors and pharmacist (95.5% and 94.0%, respectively) needed to inform patients about possible side effects of the prescribed medicine. Majority of respondents would inform their physician if they were consuming traditional medications (70.8%) and were using non-prescribed medicines bought at pharmacy (78.3%) at the same time the Western medicines prescribed. However, only a lesser percentage of the respondents would seek information about the side effects of the medicine before taking those (56.5%). Overall, the majority have indicated that medicines’ side effects can be prevented (p<0.05). Conclusion: There is a general misconception in addition to low levels of awareness and understanding among the public toward ADRs. It is anticipated that this study would be useful in designing public educational interventions to enhance the identification and reporting of ADRs.
DEVELOPMENT OF ANTICANDIDAL DRESSINGS TREATED WITH FUNGAL CHITOSAN/ZNO NANOCONJUGATES

: The potentiality of employing nanotechnology to overcome pathogenic yeast infections was investigated. Chitosan was achieved from grown mycelial biomass of Aspergillus niger, characterized and transformed to its nano-form to have fungal chitosan nanoparticles (NCT), which was further conjugated with ZnO nanoparticles (Zn-NPs) and these individual compounds were loaded onto cotton textiles and evaluated as anticandidal agents against Candida albicans and C. parapsilosis. Fungal chitosan had a deacetylation degree of 89.1 % and a 90.18 KDa molecular weight. The FTIR analysis of composited Zn/NCT indicated strong cross linkage between their particles. The Zn/NCT NPs had a mean particles’ size of 136 nm with hemispherical figure and well distribution of NPs. Both Zn-NPs, NCT and Zn/NCT nanocomposites exhibited potent anticandidal efficacy against pathogenic yeast strains, either in emulsion form or after loading onto cotton fabrics. The scanning micrographs of exposed Candida strains to Zn/NCT nanocomposites indicated complete lyses of yeast cells after 12 h of exposure. The synthesis of fungal NCT and its combination with Zn-NPs and loading them onto textiles is extremely recommended for generating bioactive anticandidal textiles.
Creating Conﬁdence Intervals for Reservoir Computing’s Wind Power Forecast Use of Maximum Likelihood Method and the Distribution-based Method

—The world is increasing the investments in electricity production from renewable sources, such as wind farms, al-though, the variable power production of wind farms must be balanced by other sources of energy, such as thermal units. As the amount of electric energy generated by the wind represents a higher percentage in the electric grid, it becomes more important to do accurate wind power forecasts and conﬁdence intervals to support the system’s operation and reduce its costs. In order to generate the conﬁdence intervals, the forecasting error is often assumed to follow a Gaussian distribution. A wrong assumption can have a huge impact on the conﬁdence intervals. This work proposes an evaluation of the forecasting error distribution generated by a Reservoir Computing network forecast in different timescales and the conﬁdence intervals generated using the maximum likelyhood method and the distribution based method.
RESEARCH METHODOLOGY FOR DESIGN OF HIGH FUNCTIONAL COMPLEXITY CLOTHING

Following the purposes of the Clothing Design program, which emphasize research processes that explore clothing from different areas, from the materials to production, the project is pre-sented within the ﬁeld of the exploration of clothing as mediator between the body (acknowl-edging it as an internal system) and its special context (as an external system). Both systems demand speciﬁc and ascertainable requirements that have been determined through research and that will answer through high complexity clothing developed for a speciﬁc sport, in this particular case artistic and rhythmic gymnastics.
Isotropy and Diffuseness in Room Acoustics: Paper ICA2016-277 Correction algorithm for sound scattering coefficient measurements

Scattering coefficient measurements according to ISO 17497-1 are very sensitive to temperature and humidity changes in the reverberant room. Even variations as small as 0.1 K can significantly influence effective reverberation times and lead to wrong results. This phenomenon puts quite stringent limitations on how scattering measurements can be performed. This article elaborates on these limitations and discusses precautions that need to be taken in practical situations. Furthermore, we verify to what extent a stretching algorithm can help to recalibrate impulse responses and improve the quality of measured data in case measurement sequences have been subject to moderate temperature variations.
Erythropoietin prevents sepsis -induced clinical severity and haematological changes in mice

We investigated the effect of erythropoietin on sepsis-induced haematological changes in mice. Sepsis was induced by caecal ligation and puncture. In this study, blood was collected after 20 ± 2 hr of surgery from Sham operated (SO), Sham operated (SO)+EPO, sepsis (CLP) and CLP+EPO. Clinical scoring was done. Septic animal showed bloated appearance, mucky eyes, lack of movement and lack of alertness. Erythropoietin treatment reduced the clinical severity in septic mice. Sepsis significantly increased haemoglobin, packed cell volume and decreased red blood cell count, white blood count and platelet count. Erythropoietin significantly reversed the haematological changes to near normal. However erythropoietin post treatment showed no significant change in white blood and platelet count. Erythrocyte indices did not reveal any changes in sepsis except MCH (Mean Corpuscular haemoglobin) which was increased. In septic mice treated with erythropoietin, significant decrease in MCH was observed. Mean platelet volume, red cell distribution width and platelet distribution widths were significantly increased in sepsis. Erythropoietin restored the red cell distribution width compared to control, but no significant change was observed in mean platelet volume and platelet distribution width in septic mice. In conclusion, erythropoietin prevents sepsis-induced haematological changes in mice, but not platelet parameters.
An Efficient Batch-Mode Scheduling Heuristic Based on Load Balancing

— In this paper, an efficient Batch-Mode scheduling heuristics have been proposed for balancing the load in the Desktop Grid environment. The proposed heuristic works in two phases: In first phase, we are making a schedule of Expected Execution Time (EET uv ) for all tasks w.r. t. resources by following Max-Min for m tasks & Min-Min and Max-Min alternatively for remaining n-m tasks, where n & m are the number of tasks (T u ) and resources (R v ) respectively. Then scheduling is being done as per the minimum EET uv taken by the tasks w.r. t. the resources without considering the load imbalance on resources. In second phase, to remove the load imbalance, tasks will get transferred from maximally loaded to minimally loaded resources. The concept has tested experimentally by using GridSim 5.2, and results proves that proposed heuristic performs well on comparing with Min-Min, Max-Min and LJFR-SJFR heuristic for minimizing Makespan, Flowtime and Average Completion Time value.
AtmosphericMeasurementTechniques Intercomparison of peroxy radical measurements obtained at atmospheric conditions by laser-induced ﬂuorescence and electron spin resonance spectroscopy

Measurements of hydroperoxy radical (HO 2 ) and organic peroxy radical (RO 2 ) concentrations were performed by two different techniques in the atmospheric simulation chamber SAPHIR in J ¨ ulich, Germany. The ﬁrst technique was the well-established Matrix Isolation Electron Spin Resonance (MIESR), which provides absolute measurements with a time resolution of 30 min and high accuracy (10%, 2 σ ). The other technique, ROxLIF, has been newly developed. It is based on the selective chemical conversion of RO x radicals (HO 2 and RO 2 ) to OH, which is detected with high sensitivity by laser-induced ﬂuorescence (LIF). ROxLIF is calibrated by quantitative photolysis of water vapor at 185 nm and provides ambient measurements at a temporal resolution of 1 min and accuracy of 20% (2 σ ). The measurements of HO 2 and RO 2 obtained by the two techniques were compared for two types of atmospheric simulation experiments. In one experiment, HO 2 and CH 3 O 2 radicals were produced by photooxidation of methane in air at tropospheric conditions. In the second experiment, HO 2 and C 2 H 5 O 2 were produced by ozonolysis of 1-butene in air at dark conditions. The radical concentrations were within the range of 16 to 100 pptv for HO 2 and 12 to 45 pptv for RO 2 . Good agreement was found in the comparison of the ROxLIF and MIESR measurements within their combined experimental uncertainties. Linear regressions to the combined data set yield slopes of 1.02 ± 0.13 (1 σ ) for RO 2 and 0.98 ± 0.08 (1 σ ) for HO 2 without signiﬁcant offsets. The results conﬁrm the calibration of the ROxLIF instrument and demonstrate that it can be applied with good accuracy for measurements of atmospheric peroxy radical concentrations.
Noble-Metal-Based Catalytic Oxidation Technology Trends for Volatile Organic Compound (VOC) Removal

: Volatile organic compounds (VOCs) are toxic and are considered the most important sources for the formation of photochemical smog, secondary organic aerosols (SOAs), and ozone. These can also greatly affect the environment and human health. For this reason, VOCs are removed by applying various technologies or reused after recovery. Catalytic oxidation for VOCs removal is widely applied in the industry and is regarded as an efﬁcient and economical method compared to other VOCs removal technologies. Currently, a large amount of VOCs are generated in industries with solvent-based processes, and the ratio of aromatic compounds is high. This paper covers recent catalytic developments in VOC combustion over noble-metal-based catalysts. In addition, this report introduces recent trends in the development of the catalytic mechanisms of VOC combustion and the deactivation of catalysts, such as coke formation, poisoning, sintering, and catalyst regeneration. according to reaction characteristics. Moreover, noble metal catalysts are used together with non-noble metals and play a role in the activity of other catalysts. Therefore, further elucidation of their function and catalytic mechanism in VOC removal is required.
Structure-based drug design studies of the interactions of ent -kaurane diterpenes derived from Wedelia paludosa with the Plasmodium falciparum sarco/endoplasmic reticulum Ca 2+ -ATPase PfATP6

Malaria is responsible for more deaths around the world than any other parasitic disease. Due to the emergence of strains that are resistant to the current chemotherapeutic antimalarial arsenal, the search for new antimalarial drugs remains urgent though hampered by a lack of knowledge regarding the molecular mechanisms of artemisinin resistance. Semisynthetic compounds derived from diterpenes from the medicinal plant Wedelia paludosa were tested in silico against the Plasmodium falciparum Ca 2+ -ATPase, PfATP6. This protein was constructed by comparative modelling using the three-dimensional structure of a homologous protein, 1IWO, as a scaffold. Compound 21 showed the best docking scores, indicating a better interaction with PfATP6 than that of thapsigargin, the natural inhibitor. Inhibition of PfATP6 by diterpene compounds could promote a change in calcium homeostasis, leading to parasite death. These data suggest PfATP6 as a potential target for the antimalarial ent -kaurane diterpenes.