Miracle-dz/UniFAR-FTUs huggingface dataset:
Spatial heterogeneity of insecticide resistance in the dengue vector Aedes aegypti in the Yucatan peninsula of Mexico presents unique vector control challenges

Spatial heterogeneity of insecticide resistance in the dengue vector Aedes aegypti in the Yucatan peninsula of Mexico presents unique vector control challenges By Regan Lee Deming Background: The emergence of insecticide resistance in vector populations around the world threatens disease prevention and control. Dengue viruses, spread primarily by the Aedes aegypti mosquito, cause significant morbidity and mortality. Dengue is controlled mainly through insecticide application for vector control since there are no preventative medications or vaccines. Understanding how insecticide resistance moves through a population, its geographical distribution and the biological mechanisms underlying resistance is essential for effective evidence-based control programs. Objective: This cross-sectional study is an initial assessment of insecticide resistance in Ae. aegypti mosquitoes across previously unstudied dengue-endemic towns in the Yucatan peninsula of Mexico. The study quantified the entomologic profile of these towns, phenotypic resistance and the frequency of two known molecular markers of resistance to certain pyrethroid insecticides. Methods: Entomological surveys of Ae. aegypti were conducted in 5 towns in Yucatan, Mexico from June-August 2013. Emerged F0-F2 adults from eggs collected in each town were exposed to insecticides; deltamethrin, bendiocarb and chlorpyrifos and tested for resistance. Individuals tested against deltamethrin were also evaluated for the presence of two kdr mutations known to be associated with pyrethoid resistance, V1016I and F1534C, to assess the validity of these as molecular markers for deltamethrin resistance. Results: CDC Bottle Bioassay tests showed high levels of resistance to deltamethrin and chrlorpyrifos, and limited resistance to bendiocarb, with variations between study towns. Frequencies ranged between 0.47-0.74 for the V1016I mutation and showed a highly significant association with deltamethrin resistance phenotype in each town (p <0.002). Frequencies ranging between 0.59-0.94 were found for the F1534C mutation, showing significant association with deltamethrin resistance phenotype in 3 of the 5 towns, (p =0.01, p <0.0001 and p<0.0001). Discussion: These data have identified heterogeneity of insecticide resistance in previously unstudied populations and offer key insights into the development of these patterns. Several driving forces lead to development of insecticide resistance in mosquito populations, including pressure from insecticide application as well as human behavior and movement patterns. Heterogeneity of resistance patterns over a small geographical area poses a challenge to vector control programs, as employing interventions at a small scale is not always feasible. Spatial heterogeneity of insecticide resistance in the dengue vector Aedes aegypti in the Yucatan peninsula of Mexico presents unique vector control challenges
0 60 10 63 v 1 3 0 Ja n 20 06 Contractivity of positive and trace preserving maps under L p norms

We provide a complete picture of contractivity of trace preserving positive maps with respect to p-norms. We show that for p > 1 contractivity holds in general if and only if the map is unital. When the domain is restricted to the traceless subspace of Hermitian matrices, then contractivity is shown to hold in the case of qubits for arbitrary p ≥ 1 and in the case of qutrits if and only if p = 1,∞. In all non-contractive cases best possible bounds on the p-norms are derived.
SOCIAL MEDIA LANGUAGE AND WELLBEING

Wellbeing is an important concept that concerns researchers, policy makers, and the broader general public. The measurement of individuals’ wellbeing levels has predominantly been done through self-reports (e.g., survey questionnaires), which is time-consuming for respondents and costly. Alternatively, wellbeing can be measured in real-time by automatically analysing the language expressed on social media platforms (e.g., Facebook, Twitter, Weibo), through social media language text mining (SMTM). The application of this method for the measurement of wellbeing is relatively new, therefore the validity of SMTM for wellbeing is still being established. We present a systematic review based on 45 studies, and a meta-analysis on 32 effect sizes from a subset of 18 studies reporting correlations between SMTM wellbeing and survey-based ground truth measures. Our qualitative synthesis of the reviewed studies provided insights into current patterns in the literature including (1) most studies were conducted in English speaking samples, (2) Twitter was the most popular social media platform for data collection, (3) closed vocabulary dictionary methods driven and word-level methods of analysis were equally preferred, (5) satisfaction with life was the most popular ground-truth measure across the studies. In addition to this, our qualitative synthesis provided support for the face validity of SMTM for wellbeing by comparing/highlighting the similarities between the broader survey-based wellbeing literature and the findings of the SMTM-based wellbeing studies. Our meta-analysis found that SMTM shows convergent validity with traditional wellbeing measures (r = .54, 95% CI [.37, .67] for location level studies, and r = .33, 95% CI [.25, .40] for individual-level assessments). SMTM is a promising and growing method, but researchers should be aware of its current pitfalls such as the non-representativeness of the samples acquired through social media platforms. We provide recommendations for future SMTM studies in the context of wellbeing.
2 4 M ay 2 02 2 Proposal for stable atom trapping on a GaNon-Sapphire chip

Aiping Liu, 4 Lei Xu, 5 Xin-Biao Xu, 5 Guang-Jie Chen, 5 Pengfei Zhang, Guo-Yong Xiang, 5 Guang-Can Guo, 5 Qin Wang, 4, ∗ and Chang-Ling Zou 5, 3, † Institute of quantum information and technology, Nanjing University of Posts and Telecommunications, Nanjing 210003, China CAS Key Laboratory of Quantum Information, University of Science and Technology of China, Hefei 230026, China State Key Laboratory of Quantum Optics and Quantum Optics Devices, and Institute of Opto-Electronics, Shanxi University, Taiyuan 030006, China Broadband wireless communication and sensor network technology, key lab of Ministry of Education, Nanjing University of Posts and Telecommunications, Nanjing 210003, China CAS Center for Excellence in Quantum Information and Quantum Physics, University of Science and Technology of China, Hefei 230026, China (Dated: May 25, 2022)
Space Group Symmetry Classification of Energy Bands in Graphene and Destruction of Dirac Points by Supercell Potential

In the previous publications (E. Kogan and V. U. Nazarov, Phys. Rev. B {\bf 85}, 115418 (2012) and E. Kogan, Graphene {\bf 2}, 74 (2013)) we presented point group symmetry classification of energy bands in graphene. In the present note we generalize classification by considering the space group symmetry. Also in the framework of group theory we describe destruction of the Dirac points in graphene by a supercell potential.
L O ] 2 4 M ay 1 99 9 Category analog of sup-measurability problem

A function F : R2 → R is sup-measurable if Ff : R → R given by Ff (x) = F (x, f(x)), x ∈ R, is measurable for each measurable function f : R → R. It is known that under different set theoretical assumptions, including CH, there are sup-measurable non-measurable functions, as well as their category analog. In this paper we will show that the existence of category analog of sup-measurable non-measurable functions is independent of ZFC. A similar result for the original measurable case is a subject of a work in prepartion by Ros lanowski and Shelah. The work of the first author was partially supported by NSF Cooperative Research Grant INT-9600548, with its Polish part financed by Polish Academy of Science PAN. This work was supported in part by a grant from “Basic Research Foundation” founded by the Israel Academy of Sciences and Humanities. Publication 695.
Studies of waveform requirements for intermediate mass-ratio coalescence searches with advanced gravitational-wave detectors

The coalescence of a stellar-mass compact object into an intermediate-mass black hole (intermediate mass-ratio coalescence; IMRAC) is an important astrophysical source for ground-based gravitational-wave interferometers in the so-called advanced configuration. However, the ability to carry out effective matched-filter based searches for these systems is limited by the lack of reliable waveforms. Here we consider binaries in which the intermediate-mass black hole has mass in the range 24 - 200 solar masses with a stellar-mass companion having masses in the range 1.4 - 18.5 solar masses. In addition, we constrain the mass ratios, q, of the binaries to be in the range 1/140 < q < 1/10 and we restrict our study to the case of circular binaries with non-spinning components. We investigate the relative contribution to the signal-to-noise ratio (SNR) of the three different phases of the coalescence: inspiral, merger and ringdown. We show that merger and ringdown contribute to a substantial fraction of the total SNR over a large portion of the mass parameter space, although in a limited portion the SNR is dominated by the inspiral phase. We further identify three regions in the IMRAC mass-space in which: (i) inspiral-only searches could be performed with losses in detection rates L in the range 10% < L < 27%, (ii) searches based on inspiral-only templates lead to a loss in detection rates in the range 27% < L < 50%$, and (iii) templates that include merger and ringdown are essential to prevent losses in detection rates greater than 50%. We investigate the effectiveness with which the inspiral-only portion of the IMRAC waveform space is covered by comparing several existing waveform families in this regime. Our results reinforce the importance of extensive numerical relativity simulations of IMRACs and the need for further studies of suitable approximation schemes in this mass range.
Beyond Coherence: The syntax of opacity in German

FELLOWSHIPS, GRANTS, AND AWARDS University of Georgia Online Learning Fellowship (co-recipient, $2,500): 2016-2017 Leibniz Universität Hannover, Germany, Fund for Internationalization ($3,352): June 15-July 24, 2015 Leibniz Universität Hannover, Germany, Visiting Scholars Program ($6,419): June 1-12, 2015 University of Georgia Ctr for Teaching and Learning Sarah Moss Fellowship ($1,800): Summer 2013 University of Georgia Provost’s Summer $5000 Research Grant: Summer 2012, 2013 University of Georgia Franklin International Faculty Exchange with Gabriele Diewald, Leibniz Universität Hannover ($2,552): Spring 2013 University of Georgia Ctr for Teaching and Learning Lilly Teaching Fellowship: 2011-2013 Swarthmore College Research Support Grant: 2006-2007, 2007-2008, 2008-2009, 2009-2010 UC Santa Cruz Department of Linguistics Graduate Student Research (GSR)-ship: Winter 2005 UC Santa Cruz Institute for Humanities Research (IHR) Dissertation Fellowship: Fall 2004 UC Santa Cruz Outstanding Teaching Assistant Award: 2004 UC Santa Cruz Doctoral Student Sabbatical Fellowship: Winter 2004 UC Santa Cruz IHR Research and Travel Grant: 2004, 2003 UC Santa Cruz Department of Linguistics Research and Travel Grant: 2005, 2004, 2003 UC Santa Cruz Graduate Student Association Travel Fund: 2003 UC Regents Fellowship: 2000-2001 National Collegiate Athletic Association (NCAA) Post-Graduation Scholarship: 1997 Boston University Department of Modern Foreign Languages and Literatures Barbara Argote Senior Award in French: 1997
Evaluating symplectic Gauss sums and Jacobi Symbols

Stark [9] has explicitly evaluated some symplectic Gauss sums when the “denominator” matrix has odd prime level. This result is useful in computing the exact tranformation formulas of multivariable theta functions (see Stark [10], Friedberg [3] and Styer [11]). It is particularly useful when considering theta functions with quadratic forms having an odd number of variables, often a troublesome case (see Eichler [2] and Andrianov-Maloletkin [1]).
Giant Gravitons - with Strings Attached (II)

Abstract: We study the one-loop anomalous dimensions of operators in the N = 4 super Yang-Mills theory that are dual to open strings ending on giant gravitons. We consider both AdS and sphere giants as well as boundstates of them. The open strings we consider carry angular momentum on an S embedded in the S of the AdS5×S background. The main result of this article is that we derive a bosonic lattice Hamiltonian that describes the one loop mixing of the operators dual to the general excited giant graviton system. A semiclassical analysis of the Hamiltonian allows us to give a geometrical interpretation for the labeling used to describe the gauge theory operators. We also argue that AdS giant gravitons are unstable against the excitations considered.
Interactions entre bifurcation par brisure partielle de symétrie sphérique

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01 08 13 6 v 1 1 6 A ug 2 00 1 Breaking CPT by mixed non-commutativity

The mixed component of the non-commutative parameter θμM , where μ = 0, 1, 2, 3 and M is an extra dimensional index may violate four-dimensional CPT invariance. We calculate one and two-loop induced couplings of θμ5 with the four-dimensional axial vector current and with the CPT odd dim=6 operators starting from five-dimensional Yukawa and U(1) theories. The resulting bounds from clock comparison experiments place a stringent constraint on θμ5, |θμ5| −1/2 >∼ 5 × 10 11 GeV. Orbifold projection and/or localization of fermions on a 3-brane lead to CPT-conserving physics, in which case the constraints on θμ5 are softened.
How to Smooth Curves and Surfaces with Splines and Cross-Validation

Abstract : The use of smoothing splines and the method of generlized cross validation (GCV) for smoothing discrete noisy data from an unknown but smooth curve is reviewed. The use of 'plaque mince' or Laplacian smoothing splines with GCV for smoothing discrete noisy data from an unknown but smooth surface is described. A numerical algorithm for this (non-trivial) computational problem is described, and an example from a Monte Carlo study is presented to show how the method works on simulated data. The results are extremely promising. Some design problems are briefly mentioned. Some conjectures are made concerning optimality properties of Laplacian smoothing splines and Laplacian histosplines.
Diagnosing and managing a giant primary cutaneous malignant melanoma of the lower limb

Abstract We present a woman who was referred to our plastic surgery unit with a suspected squamous cell carcinoma following a 3-year history of an enlarging mass on her thigh. Surprisingly, histopathological assessment confirmed the diagnosis of nodular malignant melanoma measuring 77×77×54 mm with a Breslow thickness of 52 mm, making it the largest recorded lower limb primary cutaneous malignant melanoma in the UK.
Fit Diversity, Structure and Measurability

The concept of fit and its many applications in management research is discussed. An historical perspective is given and a pool of recent papers using fit concepts on several management research areas is inspected closer. The main purpose of this essay is to grasp the epistemological variety of approaches, concepts, applications, and measurability of fit, so as to establish context contributing to the formulation of future research questions involving such a concept and inherent dimensions.
Epilepsy surgery program in a resource‐limited setting in Vietnam: A multicentered collaborative model

Although epilepsy surgery is more effective than medical therapy for drug‐resistant patients, it is underutilized in both high‐income and low‐ and middle‐income countries. In light of our efforts to establish an epilepsy surgery program in a resource‐limited setting, this study aimed to determine the outcome of the epilepsy surgery program in Ho Chi Minh City (HCMC), Vietnam.
Effects of Hibernation Site, Temperature, and Humidity on the Abundance and Survival of Overwintering Culex pipiens pipiens and Anopheles messeae (Diptera: Culicidae)

Abstract Knowledge of the hibernation site preferences and the factors which influence winter survival in these hibernation sites may enhance understanding of mosquito population dynamics after winter and how arboviruses persist in temperate regions. Our study quantified the number of adult overwintering mosquitoes in cellars and aboveground constructions and analyzed survival rates in relation to the environmental conditions in these sites. During the winters 2016/2017 and 2018/2019, 149 different constructions in Northwest Germany were sampled for mosquitoes. Mosquitoes were detected in 44% of the cellars and in 33% of the aboveground constructions. Culex p. pipiens Linnaeus was the most abundant species in cellars, whereas high numbers of Anopheles messeae Falleroni were collected from a single barn. Subsequently, an enclosure study was conducted during 2019/2020. Overwintering field-collected Cx. p. pipiens and An. messeae were divided into groups with or without fructose availability, and placed in cages with different man-made hibernations sites, where temperature and relative humidity were recorded hourly. For both species, increasing mean temperatures (5–16°C) but not mean relative humidity (58–94%) were correlated with winter mortality rates of the mosquitoes. The lipid measurements were greater and mortality rates were lower when both species were provided fructose. Larger specimens (determined by wing length) stored more lipids, and in Cx. p pipiens, but not in An. messeae, survival probability of large specimens was significantly greater than for small females. Mosquitoes showed a distinct pattern in the selection of overwintering sites, while temperature was an important driver for survival.
Cervical cancer screening and outcomes for women under 25 years of age in Belgium: a 10-year nationwide study

Objective The aim of the study was to describe trends in cervical cancer screening and outcomes for women under 25 years of age in Belgium between 2010 and 2019 in response to a changed reimbursement policy. Materials and methods We used the databases of the National Health Insurance Institute (RIZIV/INAMI) and the Belgian Cancer Registry (BCR) for a nationwide description of cervical screening, subsequent diagnostic procedures and outcomes for women younger than 20 years and women aged 20–25 years between 2010 and 2019. Results Over a 10-year period, the number of cytology screening tests and annual screening rates in women younger than 25 years have been reduced by 50%, but no increases in invasive cervical cancer or high-grade intraepithelial lesion diagnoses were observed. The major determinant of this decreased overscreening has been the limitation of reimbursement in 2013 to once every 3 years instead of once every 2 years. In women aged 25–29 years, there is no increase in invasive cervical cancer diagnoses after decreased screening of women younger than 25 years. To detect 29 invasive cervical cancers in women younger than 25 during the 10-year study period, a total of 5606 conizations were performed and 43 million EUR of Belgian health insurance budget was spent. Since the cost of hospitalization, sickness leave and negative psychological impact were not included in our estimation, these costs are underestimated. Conclusion Incidence of cervical cancer in women under 25 years remains low and screening is not effective in preventing cervical cancer, although there is clear evidence of potential reproductive harm and financial cost. We state that restricting reimbursement of cervical cancer screening before the age of 25 will improve guideline adherence and decrease healthcare expenditures without negatively impacting the health of the population.
Genome analysis of a new sulphur disproportionating species Thermosulfurimonas strain F29 and comparative genomics of sulfur-disproportionating bacteria from marine hydrothermal vents

This paper reports on the genome analysis of strain F29 representing a new species of the genus Thermosulfurimonas . This strain, isolated from the Lucky Strike hydrothermal vent field on the Mid-Atlantic Ridge, is able to grow by disproportionation of S0 with CO2 as a carbon source. Strain F29 possesses a genome of 2,345,565 bp, with a G+C content of 58.09%, and at least one plasmid. The genome analysis revealed complete sets of genes for CO2 fixation via the Wood–Ljungdahl pathway, for sulphate-reduction and for hydrogen oxidation, suggesting the involvement of the strain into carbon, sulphur, and hydrogen cycles of deep-sea hydrothermal vents. Strain F29 genome encodes also several CRISPR sequences, suggesting that the strain may be subjected to viral attacks. Comparative genomics was carried out to decipher sulphur disproportionation pathways. Genomes of sulphur-disproportionating bacteria from marine hydrothermal vents were compared to the genomes of non-sulphur-disproportionating bacteria. This analysis revealed the ubiquitous presence in these genomes of a molybdopterin protein consisting of a large and a small subunit, and an associated chaperone. We hypothesize that these proteins may be involved in the process of elemental sulphur disproportionation.
Year in review 2021: Neuromuscular diseases

In this years' review of neuromuscular respiratory medicine, there were a series of articles on home mechanical ventilation, real‐world studies assessing the impact of nusinersen, and studies describing upper airway dysfunction. Beyond this, we highlight two excellent reviews regarding cardiac dysfunction in neuromuscular diseases.
Within-category similarity negatively affects associative memory performance in both younger and older adults

ABSTRACT Associative memory involves the ability to encode and remember the relationship between individual items. This ability can become diminished when there is a high degree of similarity between stimuli that are being learned. Associative memory errors often stem from the fact that lures include a high degree of item familiarity as well as mnemonic similarity with the original associative episode. The current set of experiments examined how this overlap, in the form of within-category similarity, affects veridical and false retrieval in both younger and older adults. Across three experiments, results suggest that mnemonic overlap between targets and lures is detrimental to the ability to discriminate between highly similar information. Specifically, shared category membership for targets and lures led to increased false associative memories across age groups. These results have implications for scenarios where there is a high degree of overlap between target and lure events and indicate that these types of associative memory distinctions are difficult irrespective of age.