Miracle-dz/UniFAR-FTUs huggingface dataset:
Empathy, Agonism, Deliberation, Democracy

I believe that empathy is important for democracy. To make this case, I investigate the history of the concept of empathy from its origins in 19 th Century German aesthetic philosophy, identifying the three key components of emotion, projection and understanding. The confusion surrounding empathy today arises from its use by later scholars in the psychoanalytic and social psychological tradition. As an alternative, I adapt a multi-dimensional model called the Process Model of Empathy. Empirical research demonstrates that the process of empathy can help individuals overcome various biases and affect outgroup evaluations; these are essential for democratic decisions to give equal consideration to all citizens. I then argue that these findings are important for Chantal Mouffe's theory of agonistic pluralism, making two claims. First, agonistic pluralism cannot function without putting the process of empathy at its heart; second, this implies that agonistic pluralism places too much emphasis on conflict. As an alternative, some combination of agonism and deliberation may be preferable, though whatever theory remains persuasive, the process of empathy must play a central role in democracy.
Effectet of TEMPO Selective Oxidation on Cellulose-Morphology and Paper Properties

Bleached eucalypt pulp was selectively oxidized with 2,2,6,6-tetramethylpiperidine-1-oxyl radical (TEMPO) / NaClO/NaBr mediated oxidation system under alkaline conditions. Pulp with various amount of carboxylate groups was obtained. Optical microscope was applied to observe the morphological changes of cellulose fibers during oxidation. But no obvious change was detected. Handsheets was then prepared with various oxidized pulps and unoxidized eucalypt pulp. The effect of carboxylate content and the amout of oxidized pulp added on paper was discussed. Results showed that tightness of paper added with oxidized pulps was remained almost the same as the paper made from 100% original eucalypt pulp. Tensile index,burst index and wet tensile index was improved with the addition of oxidized pulps,while tear index decreased to some extent.
Coastal Erosion as a Natural Resource Management Problem : The State of Economic Science and Policy

Natural forces render the coastal environment an evolving landscape, with the majority of coastline in the U.S. exhibiting net erosion in recent decades. Predictions suggest that 25 percent of homes within 500 feet of the coast could be lost to erosion in the next 60 years, at a potential cost of $530 million dollars each year. Following a lengthy tradition of economic models for natural resource management, this paper explores dynamic optimization models for managing coastal erosion. The models conceptualize benefits of beach area as service flows accruing to nearby residential property owners, recreational beach users, and local businesses. The costs of maintaining beach area include pecuniary engineering expenditures, opportunity costs, as well as negative impacts on the coastal environment. Employing these constructs, an optimal control model can be specified that provides a framework for identifying the conditions under which beach replenishment is welfare-enhancing (i.e. will ―pass‖ a comprehensive benefit-cost analysis), and an optimal replenishment schedule (e.g. periodic frequency and requisite sand volume) can be derived. We review the existing literature that has attempted the empirical measurement of benefits and costs of beach replenishment. Results are scrutinized to explore ways in which geophysical shoreline processes, including stochastic variation in periodic erosion, variability in erosion in the long shore dimension, and nonlinear relationships reflecting an attempt to maintain conditions far from historical equilibriums, can be incorporated. Sea level rise is introduced as an evolving erosion rate, which provides a framework for predicting the timeline of active shoreline management (i.e. how long should we attempt to ―hold the line‖? ) and conditions under which movement to a passive management regime might be optimal. Natural resource economic approaches to shoreline erosion management are compared to and contrasted with existing U.S. Army Corps of Engineers procedures for evaluating shoreline protection projects.
53 BP 1 : Pro Choice in DNA Repair

The DNA damage response factor 53BP1 functions at the intersection of two major double strand break (DSB) repair pathways – promoting non-homologous end-joining (NHEJ) and inhibiting homology-directed repair (HDR) – and integrates cellular inputs to ensure their timely execution in the proper cellular contexts. Recent work has revealed that 53BP1 controls 5′ end resection at DNA ends, mediates synapsis of DNA ends, promotes the mobility of damaged chromatin, improves DSB repair in heterochromatic regions, and contributes to lethal mis-repair of DSBs in BRCA1-deficient cells. Here we review these aspects of 53BP1 and discuss new data revealing how 53BP1 is loaded onto chromatin and uses its interacting factors Rif1 and PTIP to promote NHEJ and inhibit HDR.
Ju n 20 20 A simple computational approach to the Susceptible-Infected-Recovered ( SIR ) epidemic model via the Laplace-Adomian Decomposition Method

Tiberiu Harko 2, 3, ∗ and Man Kwong Mak Astronomical Observatory, 19 Ciresilor Street, 400487 Cluj-Napoca, Romania, Faculty of Physics, Babes-Bolyai University, 1 Kogalniceanu Street, 400084 Cluj-Napoca, Romania School of Physics, Sun Yat-Sen University, Xingang Road, 510275 Guangzhou, People’s Republic of China Departamento de Fisica, Facultad de Ciencias Naturales, Universidad de Atacama, Copayapu 485, Copiapo, Chile
Insight For The Construction of R-T Phase Boundary in KNN Piezoceramics From The View of Energy Band Structure

The crystal structures and associated energy band structures of classic lead-based PZT (PbZr0.5Ti0.5O3) and lead-free KNN (K0.5Na0.5NbO3) piezoelectric ceramics prepared by a solid-state method are systematically studied based on the First-principles calculations. For better understanding relations between energy band structures and the phase structures in the PZT and KNN, the components PT (PbTiO3)/PZ (PbZrO3) and KN (KNbO3)/NN (NaNbO3) are also calculated. The results suggest that the vital contribution to R-T morphotropic phase boundary (MPB) in PZT comes from the hybridization of A-site and B-site ions, which causes stretching and tilting of oxygen octahedron and therefore leads to the formation of R and T phases. The KNN behaves differently. Moreover, it’s concluded that the band structure highly inherited from tetragonal PT plays an important role in the construction of the R-T phase boundary according to the comparison of PZT and KNN. In general, the work inspires an idea from the view of energy band structure to realize R-T phase coexistence as well as improved piezoelectric properties in KNN-based lead-free piezoceramics.
Clinical Outcome and Complication of Endoscopic Endonasal Transsphenoidal Surgery (ETSS) for Pituitary Adenoma: A Retrospective Study at Prime Teaching Hospital Peshawar

Objectives: The study aimed to ascertain the clinical outcome and complications of endoscopic endonasal transsphenoidal surgery (ETSS) for pituitary adenomas. Material & Methods: A retrospective study conducted at the Department of Neurosurgery Prime Teaching Hospital Peshawar, Pakistan. Pituitary adenoma was diagnosed in 89 patients on MRI Brain with contrast and post-surgical biopsy. Post-surgical outcomes and complications were documented. Results: Out of 89 patients, 54% were male, and 46% female patients. The mean age was 42 ± 5 years. Headache was reported in 92% as a most common presentation, followed by decreased visual acuity in 62 %, amenorrhea in 22%, and acromegaly in 29% of patients. Overall, the symptoms related to surgical improvement were observed in 72% of patients. A good surgical outcome was observed in 80% of patients with microadenomas, as compared to the patients with macroadenomas. The most common complication was the transient diabetes insipidus followed by Cerebrospinal fluid (CSF) leak and post-operative hematoma. Conclusion: Endoscopic endonasal transsphenoidal surgery (ETSS) is a safe, less invasive, cosmetically effective technological advancement for pituitary adenomas.
Imunoterapia antitumoral em medicina veterinária

Neoplasm treatment is carried out mainly through surgery, chemotherapy, and radiotherapy. However, despite general progress in cancer therapy, effective treatment options and even healing are still insufficient for certain cancer patients. Anti-tumor immunotherapy fits this gap since it consists of the immune system manipulating to identify and destroy neoplastic cells. In this context, the present study aims to review the literature on anti-tumor immunotherapy in veterinary medicine, side effects, and other aspects considered relevant to the different methods. Besides, the evaluation of the response pattern presented and the cells and components involved were considered. For this purpose, the search sites Medline, Scielo, and Portal CAPES were used, using the following keywords: anti-tumor immunotherapy, antineoplastic antibodies, and anticancer vaccines, for the selection of scientific articles from the last ten years. Although immunotherapy acts differently from any other type of cancer treatment, its indication is related to the tumor’s characteristics and the treatment stage in which the patient is. The literature covers the study of different anti-tumor immunotherapy strategies focusing on application in humans; however, most of the tests and responses evaluated occur in other animal species. Thus, the potential for using anti-tumor immunotherapy in veterinary medicine is clear, to stimulate immune system responses against cancer cells, preventing tumor amplification and dissemination.
Code Switching and Code Mixing Used in Skinnyindonesian24

The study focuses on discussing the types of English-Indonesian switching and mixing and the factor causing of English- Indonesian code switching and code mixing. All of data were taken from the Skinnyindonesian24 YouTube channel from two brothers of Da Lopez they are Jovial da Lopez or Kajo and Andovi da Lopez. The data is taken from School Tour video released on October 30, 2018. The data collection method in this study is library research. The library research is done by watching the School Tour video by Skinnyindonesian24 repeatedly. There are three steps in data collection. First, watch the School Tour video carefully and repeatedly to understand the content. The data were analyzed using the qualitative method, the theory applied in this study were based on the theory proposed by Wardhaugh. The result of the study shown that there were three types of code switching and code mixing found, they are tag switching inter-sentential switching, intra-switching and insertion, alternation, congruent lexicalization. The factors that caused the writer to used code switching are four factors and all of them are contained in video the Skinnyindonesian24. There are also several factors that cause the author to use code mixing, from five factors, there were three factors are found in the data, they are language dominance, language attitude, psycholinguistic motivation.
TFE3 Regulates the Function of Autophagy-Lysosome to Drive Invasion and Metastasis of Papillary Thyroid Carcinoma

Hongsheng Lu Taizhou Central Hospital Chumeng Zhu Taizhou Central Hospital(Taizhou University Hospital) Yanyun Ruan Taizhou Central Hospital(Taizhou University Hospital) Lilong Fan Taizhou Central Hospital(Taizhou University Hospital) Kena Wei Taizhou Central Hospital(Taizhou University Hospital) Qi Chen Taizhou Central Hospital(Taizhou University Hospital) Qing Wei (  weiqing1971@tongji.edu.cn ) Taizhou Central Hospital
Research Progress on Toxicity of Natural Compounds

There are many active substances in natural resources. After years of research, researchers at home and abroad have extracted active compounds and proved that these compounds have low toxicity and high efficiency, but the toxicity of these compounds cannot be ignored. In this paper, the research progress on the toxicity of compounds isolated from various natural substances is reviewed, which provides a reference for the further development and rational utilization of natural compounds.
Checklist of the lichens and lichenicolous fungi of Sierra Nevada (Spain)

espanolSe presenta el catalogo de liquenes y hongos liquenicolas de Sierra Nevada (Granada, Sureste de Espana), fruto la prospeccion llevada a cabo por la Sociedad Espanola de Liquenologia (SEL), complementada por la recopilacion bibliografica. Los autores identificaron un total de 194 taxones (171 liquenes y 23 hongos liquenicolas). Como resultado de esas identificaciones, se han encontrado 46 liquenes y 9 hongos liquenicolas que son nuevas citas para Sierra Nevada. Hasta la fecha, el catalogo incluye 551 taxones (528 liquenes y 23 hongos liquenicolas). Se confirma tanto la escasa presencia de liquenes terricolas en el piso crioromediterraneo como la ausencia de liquenes terricolas del piso alpino. EnglishA checklist of lichens and lichenicolous fungi of Sierra Nevada (Granada, southeast Spain) is presented, fruit of the collecting field trip carried out by the Spanish Lichen Society (SEL), complemented with literature references. The authors identified 194 taxa (171 lichens and 23 lichenicolous fungi). As a result of these identifications, 46 lichens and nine lichenicolous fungi are reported for the first time in Sierra Nevada. To date, the catalogue includes 551 taxa (528 lichens and 23 lichenicolous fungi). We confirm both the scarce presence of terricolous lichens in the cryoromediterranean belt and the absence of alpine belt terricolous lichens.
Potential of Natural Killer Cell Enriched Conditioned Media for Skin Care and Anti-Aging

Natural killer (NK) cell is a type of immune cell and is known to be particularly responsible for innate immunity such as anti-cancer immunity, defense mechanisms against infections, and secretion of various cytokines and chemokines for increasing recruitment of other immune cells. In this study, we investigated the potentials of NK-enriched lymphocytes (NKEL) conditioned media (CM) on skin care for cosmeceutical compositions. Various cytokines of NKEL CM can improve wound healing through epithelial-mesenchymal transition (EMT) by increasing KLKs (kallikreins) and reduce metalloproteinase (MMP)-1 and MMP-2 to inhibit wrinkle formation. Our results suggest that NKEL CM which has various cytokines promotes up-regulation of cell migration and KLKs and down-regulation of MMP-1 and MMP-2 by stimulating HaCaT keratinocytes migration. Therefore, NKEL CM can be used as a cosmetic composition that can play a role in skin regeneration and anti-aging.
Borsa İstanbul’da Getiri ve Oynaklık Üzerinde Ocak Ayı Etkisinin Testi

: January effect means that stock returns are higher in January than in any other month of the year. The aim of this study is to investigate whether there is a January effect on Borsa İstanbul (BIST 100) stock returns and volatility with GARCH, EGARCH and TGARCH models. For this purpose, the daily stock return closing values covering the period of 04.01. 2010-18.02. 2020 were used. According to the findings, while January effect was observed on stock returns, no effect was found on volatility. In addition, it was determined that negative shocks are more effective than positive shocks in EGARCH and TGARCH models created to determine leverage effect.
Chapter 8:Structure and Dynamics of Supercoiled DNA Knots and Catenanes

Circular DNA molecules in vivo form catenanes and knots during such processes as replication or recombination. In addition, DNA molecules are often subjected to a torsional tension, which results in their supercoiling. The interplay between catenation, knotting and supercoiling leads to unexpected conformational changes of entire DNA molecules, and this has interesting physical and biological consequences. We show in this chapter how modelling DNA as a semi-flexible ribbon can be applied to get information about the molecular conformation of DNA molecules with complex topologies. In particular, our results highlight the importance of the chirality of knots and catenanes in the structural changes induced by DNA supercoiling. For example, strongly linked right-handed toroidal DNA catenanes undergo a specific folding that can be reversed by the introduction of negative supercoiling in each chain, or the shape of negatively supercoiled DNA trefoil knots depends on their chirality. In each case, we perform dynamical simulations including hydrodynamics, to investigate the consequences of these structural changes on the sedimentation and gel electrophoretic behaviour of the modelled knotted and catenated DNA molecules.
Growth aspirations in SMEs: managerial determinants and organizational outcomes

PurposeThe main purpose of this study is to increase the scholarly understanding of managerial growth aspirations in small firms. Research has shown that managers' aspirations are important to ensure firms' growth, but researchers know less of where their aspirations come from and how variation in these aspirations shapes organizational outcomes. By focusing on two growth strategies of particular importance for small firms – innovation and internationalization – the authors map out how managers' ambitious aspirations may create negative organizational effects and also how they may counteract such effects.Design/methodology/approachThe study employs structural equation modeling (SEM) on a sample of 249 Norwegian small- and medium-sized enterprises (SMEs). FindingsThe findings of this study suggest that managerial experience is associated with high aspirations as well as high change effectiveness on the managerial team. The authors find that ambitious growth aspirations are associated with exploration in the form of radical innovation but also lead to reduced employee well-being. Managers' level of perceived change effectiveness, on the other hand, is positively associated with radical innovation and also raises employee well-being.Research limitations/implicationsThis study highlights the positive and negative effects of managerial aspirations on different organizational outcomes. Further, it shows that managerial teams working effectively together in the face of change is important for the well-being of employees. Results confirm the positive relationship between aspirations for growth and applied growth strategies in organizations. The data sample is, however, extracted from one country only, and the authors cannot exclude the possibility that findings will be different elsewhere.Practical implicationsTo ensure successful growth, managers should combine ambitious aspirations with attention to the top management team's (TMT) experience levels and change effectiveness. Assessment of possible needs for development and adjustments could ensure growth processes with limited negative effects for employee well-being.Originality/valueBy distinguishing between growth through international sales (exploitation) and growth through a more change-intensive strategy of radical innovation (exploration), the authors investigate how variations in managerial aspirations and perceptions influence organizational growth processes. This paper paints a unique picture of how managers can be both the cause and cure of employee well-being in change-demanding situations.
Alkaline solution as a control of Botrytis cinerea, Rhizopus stolonifer, Salmonella spp. and Escherichia coli growth in strawberry (Fragaria x ananassa)

Post-harvest treatments of fruits and vegetables can help to reduce the attack of microorganisms especially the presence of pathogenic microorganisms. Alkaline water solutions were used to control of the growth of Botrytis cinerea, Rhizopus stolonifer, Salmonella spp. and Escherichia coli in strawberry (Fragaria x ananassa). Strawberries were inoculated with the microorganisms and afterwards were immersed in alkaline solutions of pH 11, 12 and 13. In vitro microbiological analyses were used to evaluate the presence of the microorganisms after fruit immersion in alkaline solutions, while the disc diffusion method was used to study the inhibition of microorganism growth. According to the results, alkaline solutions at pH 13 can be utilized to control Botrytis cinerea and Rhizopus stolonifer in strawberries. The immersion of strawberries in alkaline solutions at pH 13 for 60 min allowed to control in vitro development of Salmonella spp. and Escherichia coli.
Odor Problems in Lake Biwa

In 1969 a musty odor was first found in the southern basin of Lake Biwa. Since then we have been investigating the causes of the problem. In the 19709s musty odor problems commonly occurred from May to early June due to the metabolites produced by Phormidiumtenue. However, the problem which took place in the summer of 1981 was found to be caused by an algal bloom of Anabaenamacrospora. The analyses of the water taken in the lake as well as of the laboratory cultures of the blue-green algae led to the conclusion that 2-methylisoborneol is produced by Phormidiumtenue, whereas geosmin by Anabaenamacrospora. Purge and trap concentration followed by mass fragmentography was developed and applied as a measurement method for these two odorous compounds. The method was found to be rapid, reproducible and sensitive enough to detect them at a nanogram per liter concentration level or beneath their threshold odors, requiring only a small sample (100 ml). Slow sand filtration was found to be effective in removing odor, where the odorous compounds were reduced to less than 10 ng/l in the effluents.
Development Of Software For Solving Multistage Problems By The Method Of Dynamic Programming With Separabel Breaking

This paper discusses how to solve multi-step processes in the form of a matrix and solve problems through dynamic programming. Typically, in practice, the problem of constructing models of multi-stage processes is, as a rule, complicated by the versatility, uncertainty and nonlinearity of the modeled objects, complete or partial lack of expert experience and analytical description of the dependencies. The transition from one state to another is manifested as a function, and when the study is carried out at the analytical level, additional conditions are required, such as the production of the first, sometimes the second, function. If we express the state of multi-step procedures in the form of a matrix, the problem can be solved using dynamic programming