Miracle-dz/UniFAR-FTUs huggingface dataset:
Optimization of Packaging Process Parameters Using Combined Taguchi Method-present Worth Method/Inflationary Factor Validated

In a previous article, the packaging optimization literature illustrated how to optimize the packaging parameters using the classical Taguchi approach. Notwithstanding, it is compelling to bridge the gap created in the article for further advancement. Thus, this paper contributes to expanding scholarship regarding the area. The paper targets the Taguchi methodical optimization literature in which several scores of research across engineering disciplines and beyond have been undertaken. At present, evaluation using the Taguchi method often stops at the determination of the optimal settings from the response table through a chain of steps from factor-level selection, orthogonal array choice, signal-to-noise determination, and response table evaluation to emerge the optimal parameters. There is no information on the economic aspects of the parameters, yet processes are expected to be sustainable while economic factors play a central role. A novel idea of the present work is introduced where the interest rate and inflationary factor with levels are used to determine the economic strength of each parameter through ranking. Data was collected from a brewery process, and literature data concerning cold arc welding parametric evaluation was used. The outcome demonstrates the workability of the method in the packaging plant and cold arc welding process. The work is useful for packaging managers and welding engineers for planning purposes.
Improving wildfire management outcomes: shifting the paradigm of wildfire from simple to complex risk

Numerous wildfire management agencies and institutions rely primarily on simple risk approaches to wildfire that focus on technical risk assessments that do not reflect the complexity of contemporary wildfire risk. This review paper argues that such insufficiently complex conceptualizations of risk, which do not account for the social and ecological diversity of fire-prone areas, are key contributors to the continued wildfire dilemma. We discuss distinctions between approaching wildfire as a simple and a complex risk and illuminate the need for expanded and complimentary ways to further fire adaptation. We then share five principles to guide approaching wildfire as a complex risk to increase adaptation to and coexistence with wildfire. Such efforts are more likely to yield socially relevant and legitimate strategies for building wildfire adapted communities by recognizing and accounting for the complexities of wildfire governance amongst a variety of stakeholders who may operate at various scales using different knowledge systems.
Multiparameter magnetic resonance imaging in the diagnosis of herpes encephalitis in children

Introduction. This study is determined with the high prevalence of encephalitis in children, as well as the severe course and the possible disability. Herpes encephalitis occurs in almost half of cases of viral encephalitis in children. It is known that changes on the brain magnetic resonance imaging (MRI) in the acute stage of the disease are detected more often than on brain computed tomography (CT), but the clarification of this brain MRI changes is needed.Objectives of the study. To assess the features of brain multiparametric MRI changes in herpes encephalitis in children.Materials and methods. Two groups of children were examined, the first group included 25 children aged 6,0±4,8 years with laboratory-confirmed acute EH, the second group (control) — 23 children without signs of central nervous system damage at the comparable gender and age. Structural changes were assessed using MRI of the brain in T1-WI, T2-WI, Flair, T1-WI modes post contrast, DWI, DTI and MR spectroscopy.Results. In 40% of cases revealed panencephalitis, 36% — leukoencephalitis, 24% — polioencephalitis. Most often, the process involved the cerebral hemispheres — 72%, the brain stem — 44%, the thalamus — 40% and basal nuclei — 36%. In 52% of cases changes in DWI were found, in 20% of cases the lesions accumulated contrast agent. There was a statistically significant decrease of FA both in the focus and in the intact area in children with EH compared with the control group.Conclusion. The application of multiparametric MRI using DWI, DTI, and MR spectroscopy methods are statistically significant for the detection and assessment of focal brain lesions in children with herpes encephalitis.
Variations in the Human Serum Albumin Gene: Molecular and Functional Aspects

The human albumin gene, the most abundant serum protein, is located in the long arm of chromosome 4, near the centromere, position 4q11–3. It is divided by 14 intervening introns into 15 exons, the last of which is untranslated. To date, 74 nucleotide substitutions (mainly missense) have been reported, determining the circulating variants of albumin or pre-albumin. In a heterozygous state, this condition is known as alloalbuminaemia or bisalbuminaemia (OMIM # 103600). The genetic variants are not associated with disease, neither in the heterozygous nor in the homozygous form. Only the variants resulting in familial dysalbuminaemic hyperthyroxinaemia and hypertriiodothyroninaemia are of clinical relevance because affected individuals are at risk of inappropriate treatment or may have adverse drug effects. In 28 other cases, the pathogenic variants (mainly affecting splicing, nonsense, and deletions), mostly in the homozygous form, cause a premature stop in the synthesis of the protein and lead to the condition known as congenital analbuminaemia. In this review, we will summarize the current knowledge of genetic and molecular aspects, functional consequences and potential therapeutic uses of the variants. We will also discuss the molecular defects resulting in congenital analbuminaemia, as well as the biochemical and clinical features of this rare condition
Estimativa das porosidades efetiva e total em solos Brasileiros

Este trabalho trata das relações entre as porosidades efetiva e total e algumas características físi - cas e hídricas de solos brasileiros. A obtenção indireta das porosidades valeu-se de diversas propriedades do so lo, tais como textura, índices físicos e inclusive da condutividade hidráulica. Estes dados foram deter mi na - dos para este estudo ou obtidos da literatura especializada. As relações são dadas por equações obtidas por regres são não-linear múltipla, em que os valores previstos foram confrontados com os medidos, para verifica - ção de sua adequabilidade mediante métodos estatísticos. Testes como coeficiente de determinação, teste t, erros padrão da estimativa e médio permitiram observar que, apesar da dispersão de resultados pela medição da permeabilidade do solo ou da não utilização de outros parâmetros para previsão, tais como a matéria orgâ - ni ca, podem ser obtidas previsões de porosidades total e efetiva muito significativas em relação às encontradas por outros autores, isto para uma ampla faixa de texturas e condutividades hidráulicas.
Characteristics of Teaching Staff in Independent Colleges

Faculty construction is the stranglehold over the development of independent colleges.To solve this problem,independent college should give full play to the advantages of the flexibility of employing mechanism;realize its actual situations create a distinguished system through constructing a selection mechanism of attracting talents,an applying mechanism of competing and flowing,a mechanism for teacher development,a regulate and flexible management mechanism for part-time teacher and an incentive mechanism which regards salary distribution system reform as the core.
The Effect of Eicosapentaenoic Acid on Hepatic Metabolism and Intracellular Lipid Droplet Dynamics in An in Vitro Model of Hepatic Steatosis

Background Intra-hepatocyte triglyceride accumulation is the hallmark of non-alcoholic fatty liver disease (NAFLD). Little is known of the role of lipid droplets in the pathogenesis of this increasingly common condition. Eicosapentaenoic acid (EPA), an omega-3 fatty acid, has been suggested as a potential treatment for NAFLD. Within this study we explore different energy substrates with and without EPA and evaluate biochemical markers alongside lipid droplet characteristics. Methods EPA was added to C3A cells incubated in standard media, oleate (which mimics simple steatosis) or lactate, pyruvate, octanoate and ammonia (LPON), mimicking pathophysiology of NAFLD. At 72 hours, glucose, ketone bodies and various markers of liver function were assessed and triglyceride content was determined using confocal images of cells stained with BODIPY 493/503 and DAPI. Z stacks of confocal images were analysed using Volocity 3D image analysis and Visual Basic software to estimate the physical characteristics of lipid droplets. Liver function was assessed by measuring AST, albumin and LDH. Results Albumin levels increased in control and oleate and LDH showed EPA did not affect viability in concentrations up to 250µm. There was no effect to AST with addition of EPA. Glucose and ketone bodies were reduced in LPON treated cells in a dose dependent manner. EPA reduced triglyceride concentrations and lipid droplets per nucleus in untreated cells compared with control, however, there was no significant difference to total triglyceride concentration of cells treated with oleate + EPA or LPON + EPA. Lipid droplet volume increased in both fat loaded models with the addition of EPA, but untreated control remained the same. Surface area of lipid droplets was higher in oleate model compared to LPON. Conclusion The LPON + EPA model shows reduction of glucose and ketone bodies in a dose dependent manner indicating EPA may be useful as an adjunct to treatment of type 2 diabetes. Accumulation of lipid droplets at different rates and physical characteristics compared to oleate may reflect differences in FFA metabolism or their incorporation into the cell and lipid droplet membrane.
Urgency of Electronic Licensing Management Licensing Services in Improving the Community Economy

—This study aims to examine the urgency of providing integrated electronic licensing management in improving the community's economy. The location that is the focus of this research is the Lampung Province Investment and One Stop Integrated Services Office. This is because most people in Lampung have small, medium and large businesses. The legal basis for this electronic licensing service is Government Regulation No.24/2018 concerning Electronic Integrated Licensing Services and its Registration Mechanism. The achievement in the economic sector in Lampung Province is one of the supporting factors is the growth of quite good investment. In order to be able to produce a conducive investment climate, of course, a series of public policies are needed that support the achievement of a conducive investment climate, namely by doing business indicators, one of which is the speed of licensing. Efforts to increase investment, both small and large investments, continue to be made, both in the form of improving supporting infrastructure and in terms of licensing bureaucracy. In the case of the licensing bureaucracy to create smooth investment and business, a one-stop integrated service policy is applied. The policy was made in order to reduce obstacles that occur and accelerate the process of business and investment licensing. With the ease of integrated licensing online, it can make it easier for entrepreneurs to register their businesses, and can make it easier to obtain business permits. The ease of doing business permits will improve the economy of the community both internationally and locally, especially people who become entrepreneurs in Lampung Province. In addition to providing convenience for business licensing, the urgency of management services can also be useful for improving the principles of good governance of local governments related to democracy and empowerment, services, transparency and accountability, participation, partnerships, decentralization, and policy consistency and legal certainty.
Smart Slate Game and Students Academic Performance in Educational Technology, University of Calabar, Nigeria

The study examined the effect Utilization of Smart Slate Game (SSG) on year two students’ academic performance in Educational Technology in the University of Calabar, Nigeria. Two purpose of the study and two null hypotheses were formulated to guide the study, Quasi-experimental research design using pre-test posttest non-randomized control group design was adopted for the study. The population is made up of all Educational Technology students in the University of Calabar. A sample of 131 year two students of educational technology comprising of 66 students (26 males and 40 males) in the experimental group and 65 students (28 males and 37 females) in the control group were purposively sampled for the study. The Smart Slate Game and Educational Technology Performance Test (ETPT) were the instruments used for data collection. The results of the study were analyzed using Analysis of Covariance (ANCOVA). The results revealed that there is a significant difference in academic performance of educational technology students taught with smart slate game and those taught using expository method, there was also a significant difference in performance between male and female students taught using the Smart Slate Game, there was no significant difference in cognitive abilities of Educational Technology students when using Smart Slate Game. It was therefore recommended smart slate game technology should be used always to promote students academic performance in educational technology and that teachers should effectively design their lesson plans with Smart Slate Game to foster group task and have fun while learning.
Functional Printing of Silver Nano Ink on Injection Molded Polymeric Substrates

Over the last decades ink-jet printing has developed in many applications. The direct writing of materials such as silver (for conductive circuits) or polymers (for insulation or second layer) is an attractive method to reduce costs and save raw materials. In this article we investigate the geometrical and electrical properties of conductive circuit lines on thermoplastic substrates, depending on the printing parameters such as line width, orientation of the lines and density of the printed drops (dots per inch = dpi)First the surface of the substrates is scanned by a confocal laser scanner. The substrates (size 60mm x60 mm) are subdivided in 80 x 80 parts with a side length of 0.8mm. The 2D roughness (Sa) of these little parts is calculated and as a result the locally solved roughness of the substrates is determined. Homogeneity and surface quality of the surfaces can be evaluated.On the different polymeric substrates conductors (length 25mm) are printed with a printing head with 16 nozzles and with different orientations (parallel, horizontal and in an angle of 45° to the movement of the printing head). Also different dpi numbers (600, 900 and 1200) are used and the line width in the bit pattern is increased from 1 pixel to 5 pixels. The line width in μm depending on the line width in pixel is measured. The quality of the printed lines is quantified by calculating the deviation of the printed lines to a “perfect straight line” with the same width. The resistivity of the conducting lines and the reliability of the process are determined.
Impact of Co-Delivery of EGCG and Tuna Oil within a Broccoli Matrix on Human Gut Microbiota, Phenolic Metabolites and Short Chain Fatty Acids In Vitro

(-)-Epigallocatechin gallate (EGCG) and tuna oil (TO) are beneficial bioactive compounds. EGCG, TO or a combination of, delivered by broccoli by-products (BBP), were added to an in vitro anaerobic fermentation system containing human fecal inocula to examine their ability to generate short-chain fatty acids (SCFA), metabolize EGCG and change the gut microbiota population (assessed by 16 S gene sequencing). Following 24 h fermentation, EGCG was hydrolyzed to (-)-epigallocatechin and gallic acid. EGCG significantly inhibited the production of SCFA (p < 0.05). Total SCFA in facal slurries with BBP or TO-BBP (48–49 µmol/mL) were significantly higher (p < 0.05) than the negative control with cellulose (21 µmol/mL). EGCG-BBP and TO-EGCG-BBP treatment increased the relative abundance of Gluconacetobacter, Klebsiella and Trabulsiella. BBP and TO-BBP showed the greatest potential for improving gut health with the growth promotion of high butyrate producers, including Collinsella aerofaciens, Bacillus coagulans and Lactobacillus reuteri.
Anti-Inflammatory Effects Of Calcitriol-Treated Mesenchymal Stem Cells On Experimental Ulcerative Colitis

Objective — Ulcerative colitis is an inflammatory bowel disease usually affecting the innermost lining of the colon and rectum. Both corticosteroids and anti-inflammatory drugs are administrated as medical treatment for UC. However, these drugs, in addition to chemical side effects, impose exorbitant costs on patients. Therefore, extensive studies are underway to find new treatment approaches. This study aims to determine the effect of calcitriol-treated mesenchymal stem cells in the UC treatment. Material and Methods — This experimental study was performed on 50 Wistar rats with inducing ulcerative colitis model by 4% acetic acid. MSCs were isolated from rat bone marrow and proliferated in an appropriate medium. Bone marrow-derived mesenchymal stem cells were injected intraperitoneally. Symptom severity of this disease was evaluated using the factors, such as stool consistency, fecal blood and histopathological study of colon tissue. Furthermore, the levels of myeloperoxidase, nitric oxide and inflammatory cytokines like IL1, IL6 and TNF-α were measured using ELISA technique. Results — The results showed that calcitriol-treated MSCs, significantly reduced the production of inflammatory cytokines including IL-1 (150.22±29.04)(P<0.01), IL-6 (681±56.20)(P<0.01), TNF-α (53.07±11.30)(P<0.01) and significantly decrease in level of NO (12.86±5.65)(P<0.01), MPO (0.175±0.024)(P<0.01) and the destruction of intestinal crypts compared to the control group (P<0.05). Conclusions — It seems that using calcitriol with MSCs has reduced the symptoms of UC in our experimental model. Due to their ease of isolation and expansion, MSCs can be used as an adjunctive therapy to improve the condition of patients with UC colitis.
Kepuasan Mahasiswa Terhadap Kualiti Kehidupan Di Kolej 10, Universiti Teknologi Malaysia, Skudai, Johor

Kajian ini bertujuan untuk mengenalpasti kepuasan mahasiswa terhadap kualiti kehidupan di Kolej 10. Kepuasan mahasiswa terhadap kualiti kehidupan ini ditinjau dari lapan aspek iaitu persekitaran, kemudahan dan perkhidmatan, layanan staf dan ahli jawatankuasa mahasiswa kolej kediaman, pentadbiran pejabat, keseluruhan pengalaman, pengawasan dan keselamatan, program dan aktiviti yang dijalankan, dan perkhidmatan makanan. Kajian deskritif ini menggunakan soal selidik sebagai instrumen kajian dan melibatkan seramai 305 responden Kolej 10 yang dipilih secara rawak. Data dianalisa dengan menggunakan perisian Statistical Packages for Social Sciences (SPSS) dan dapatan dinyatakan dalam bentuk kekerapan, peratusan dan min. Dapatan kajian menunjukkan bahawa mahasiswa berpuashati terhadap kualiti kehidupan di Kolej 10 dalam semua lapan aspek yang dikaji. Kajian ini juga memajukan cadangan untuk menambahbaik kepuasan mahasiswa terhadap kualiti kehidupan di kolej kediaman dan cadangan kajian lanjutan yang boleh dilakukan.
SUPPLY CHAIN MANAGEMENT, SIMULATION & SYSTEM DYNAMICS OF AN IRON FOUNDRY

Supply chain management plays a vital role in the growth of the industry, survival in the market, the production rate and the dynamic interaction among the suppliers and the customers. Strategic decision makers need comprehensive models to guide them in efficient decision making that increases the profitability of the entire chain. System dynamic is a methodology whereby complex, dynamic and nonlinear interactions can be understood and analyzed. The objective of the paper to show the system dynamic and simulation model for iron foundry to control inventory, and also to make the inventory policies. This paper presents a simulation of supply chain model of a medium size industrial iron foundry which will produce gray cast iron and Spheroidal graphite cast iron, and also the dynamic interaction between the variables using system dynamic approach. Under different delay conditions, rejection rates, conditions, the policy experimentations carried out considering various factors of the foundry and their degree of development. The model results have been discussed and validated based on the actual results of a foundry. This paper has addressed many important issues related to demand, inventory, production rates of a foundry
ТЕОРИЯ И МЕТОДИКА ПРЕПОДАВАНИЯ ФИЛОЛОГИЧЕСКИХ ДИСЦИПЛИН В ШКОЛЕ И ВУЗЕ 

A b s t r a c t . The article aims at clarifying the premises of modelling educational outcomes of second language (L2) teachers’preparation by defining two core aspects of their professional competence architecture. From the perspectives of the communicative competence approach and the plurilingual approach to language teaching, metalinguistic awareness and plurilingual mindset are presented as the L2 teacher’s core characteristics deter - mining the efficiency of his/her professional functioning and the appropriateness of using L2 in a variety of pro - fessional contexts. The specific type of metalinguistic reflection emerging in prospective L2 teachers (teacher metalinguistic awareness) is described as including (1) performance-driven language awareness acquired as the consequence of the gradual accumulation of language use experience; (2) critical metalinguistic awareness root - ed in theoretical linguistic thinking; (3) metalingual knowledge; (4) awareness of language from learner’s per - spective. It is shown that professional plurilingual / pluricultural mindset provides the L2 teacher with a set of presuppositions, thought content and focus for mobilizing plurality of languages for effective communication and identifying resources for language teaching and professional communication by flexible adjusting integrat - ed L1-L2 repertoire. An attitude of openness and worldviews curiosity, a focus on recognizing cultural diversity and a purposeful engagement of the interrelated repertoire of several languages in communication are described among the key elements of professional plurilingual / pluricultural mindset. It is concluded that an intensive pro - motion of awareness-raising activities aimed at enhancing teacher metalinguistic awareness and plurilingual / pluricultural mindset are supposed to contribute to prospective L2 teachers’acquiring professional autonomy and the sense of professional self.
Modelling and Analysis of Performance Characteristics in a 60 Ghz 802.11ad Wireless Mesh Backhaul Network for an Urban 5G Deployment

With the widespread deployment of 5G gaining pace, there is increasing interest in deploying this technology beyond traditional Mobile Network Operators (MNO) into private and community scenarios. These deployments leverage the flexibility of 5G itself to support private networks that sit alongside or even on top of existing public 5G. By utilizing a range of virtualisation and slicing techniques in the 5G Core (5GC) and heterogeneous Radio Access Networks (RAN) at the edge, a wide variety of use cases can be supported by 5G. However, these non-typical deployments may experience different performance characteristics as they adapt to their specific scenario. In this paper we present the results of our work to model and predict the performance of millimeter wave (mmWave) backhaul links that were deployed as part of the Liverpool 5G network. Based on the properties of the 802.11ad protocol and the physical characteristics of the environment, we simulate how each link will perform with different signal-to-noise ratio (SNR) and Packet Error Rate (PER) values and verify them against real-world deployed links. Our results show good convergence between simulated and real results and provide a solid foundation for further network planning and optimization.