Miracle-dz/UniFAR-FTUs huggingface dataset:
In Situ Hydrogel Formulation for Advanced Wound Dressing: Influence of Co-Solvents and Functional Excipient on Tailored Alginate–Pectin–Chitosan Blend Gelation Kinetics, Adhesiveness, and Performance

Chronic skin wounds affect more than 40 million patients worldwide, representing a huge problem for healthcare systems. This study elucidates the optimization of an in situ gelling polymer blend powder for biomedical applications through the use of co-solvents and functional excipients, underlining the possibility of tailoring microparticulate powder properties to generate, in situ, hydrogels with advanced properties that are able to improve wound management and patient well-being. The blend was composed of alginate, pectin, and chitosan (APC). Various co-solvents (ethanol, isopropanol, and acetone), and salt excipients (sodium bicarbonate and ammonium carbonate) were used to modulate the gelation kinetics, rheology, adhesiveness, and water vapor transmission rate of the gels. The use of co-solvents significantly influenced particle size (mean diameter ranging from 2.91 to 5.05 µm), depending on the solvent removal rate. Hydrogels obtained using ethanol were able to absorb over 15 times their weight in simulated wound fluid within just 5 min, whereas when sodium bicarbonate was used, complete gelation was achieved in less than 30 s. Such improvement was related to the internal microporous network typical of the particle matrix obtained with the use of co-solvents, whereas sodium bicarbonate was able to promote the formation of allowed particles. Specific formulations demonstrated an optimal water vapor transmission rate, enhanced viscoelastic properties, gel stiffness, and adhesiveness (7.7 to 9.9 kPa), facilitating an atraumatic removal post-use with minimized risk of unintended removal. Microscopic analysis unveiled that porous inner structures were influencing fluid uptake, gel formation, and transpiration. In summary, this study provided valuable insights for optimizing tailored APC hydrogels as advanced wound dressings for chronic wounds, including vascular ulcers, pressure ulcers, and partial and full-thickness wounds, characterized by a high production of exudate.
Enhancing the Anti-Tyrosinase Activity of a Hypersaline Kitasatospora Sp. Sbsk430 by Optimizing the Medium Components

CURRENT SCIENCE, VOL. 116, NO. 4, 25 FEBRUARY 2019 649 *For correspondence. (e-mail: drsavitakerkar@gmail.com) 22. Mehta, M. and Sanjay Arora, Soil microbial biomass and activity in salt affected coastal soils under different land uses. In: Proceedings of National Conference on ‘Advanced Trends in Applied Sciences and Technology’, SES, SICE, Surat, 2012, pp. 433–437. 23. Khursheed, S. , Sanjay Arora and Ali, T. , Effect of different organic sources on biochemical properties in Typical Inceptisols of Jammu. Prog. Agric. , 2012, 12(2), 348–353. 24. Tripathi, S. , Chakraborty, A. , Chakrabarti, K. and Bandyopadhyay, B. K. , Enzyme activities and microbial biomass in coastal soils of India. Soil Biol. Biochem. , 2007, 39, 2840–2848. 25. Perucci, P. and Scarponi, L. , Effects of the herbicide imazetapir on soil microbial biomass and various soil enzyme activities. Biol. Fertil. Soils, 1994, 17, 237–240. 26. Menon, P., Gopal, M. and Parsad, R. , Effects of chlorpyrifos and quinalphos on dehydrogenase activities and reduction of Fe in the soils of two semi-arid fields of tropical India. Agric. Ecosyst. Environ. , 2005, 108, 73–83. 27. Schuster, E. and Schroder, D. , Side-effects of sequentially and simultaneously applied pesticides on non-target soil microorganisms: Laboratory experiments. Soil Biol. Biochem. , 1990, 22, 375– 383. 28. Khursheed, S. , Arora, S. and Ali, T. , Effect of organic sources of nitrogen on rice (Oryza sativa) and soil carbon pools in Inceptisols of Jammu. Int. J. Environ. Pollut. Solu. , 2013, 1, 17–21.
#Ayotzinapa, origin and evolution of the mexican social movement on Twitter #Ayotzinapa, origen y evolución del movimiento social mexicano en Twitter

Mexico was shocked once again in September 2014 over the missing Ayotzinapa students - 43 of themnews, all from the Rural Normal Guerrero State School in southern Mexico City. Social networks, already in use by movements like #YoSoy132, witnessed the Mexicans’ claim. Twitter was the most popular to express the people’s claim to the Mexican government asking to return students alive. In this article, we show the study results of a large corpus composed by #Ayotzinapa tweets. Moreover, we also especially study, the young discursive genre labels, whose anonymity, minimalism and communicative speed, can reveal some facets of the government’s strongest criticisms. Our hypothesis states that from the popular use of the associated hashtags there is an evolution of them in order to reach a wider audience. Our findings show that labels’ transformation is required, over time, to remain in the social network.
Sosialisasi Penerapan Kepemimpinan Situasional Berbudaya Organisasi untuk Meningkatkan Kinerja Perawat

Latar Belakang: kesalahan penerapan gaya kepemimpinan bagi manajer keperawatan berdampak pada kinerja dan produktivitas kerja perawat. Dampak lain juga mempengaruhi kepuasan dan loyalitas pelanggan serta kualitas pelayanan kesehatan. Tujuan dari kegiatan pengabdian masyarakat ini adalah mensosialisasikan penerapan gaya kepemimpinan situasional berbudaya organisasi untuk meningkatkan kinerja perawat di rumah sakit. Metode: Kegiatan utama yang dilakukan adalah penyampaian materi sosialisasi yang dilanjutkan dengan kegiatan FGD (Focus Group Discussion) yang dilakukan di awal dan akhir kegiatan dengan menggunakan formulir diskusi situasi kondisi staf sebagai bahan evaluasi dengan 8 pernyataan kepada 18 manajer keperawatan. Hasil: Terdapat perubahan sikap dan kesamaan persepsi responden tentang penerapan gaya kepemimpinan situasional berbudaya organisasi untuk meningkatkan kinerja perawat sebelum dan sesudah dilakukan sosialisasi. Kesimpulan: kegiatan sosialisasi dapat diterima, diapresiasi, dan dapat diterapkan oleh pengelola keperawatan sebagai upaya peningkatan kinerja perawat di rumah sakit dengan pedoman penelitian dan modul pembelajaran yang telah disampaikan.
Rôle (structure et fonction) des communautés procaryotes (bactéries et archées) dans le cycle de l’azote d’une vasière littorale du Pertuis Charentais : influence des facteurs biotiques et abiotiques par une approche multi-échelle

Dans les vasieres intertidales dominees par les diatomees, la production primaire est particulierement forte a maree basse. Ce microphytobenthos peut etre limite par les nutriments azotes en lien avec les communautes de procaryotes impliquees dans le cycle de l’azote. Ainsi, ce travail de these cherche, via une approche ecologique, a decrire le role des communautes de procaryotes benthiques notamment liees au cycle de l’azote et ce, suivant differentes echelles temporelles liees aux cycles du microphytobenthos. Des echantillons de sediment ont ete preleves dans la baie de Marennes-Oleron (Cote Atlantique, France) entre 0 et 10 cm de profondeur suivant 5 couches (0-0,5 cm, 0,5-1 cm, 1-2 cm, 2-5 cm, 5-10 cm). Differents facteurs biotiques et abiotiques ont ete mesures et mis en relation avec la production bacterienne, les activites enzymatiques et les genes fonctionnels lies au cycle de l’azote (impliques dans la nitrification, la denitrification et l’anammox). De plus, la diversite bacterienne et archeenne a ete evaluee par pyrosequencage 454 afin de caracteriser les communautes et leurs dynamiques en lien avec les facteurs forcants biotiques et abiotiques. Dans le but d’evaluer l’influence des parametres abiotiques et de la production du microphytobenthos, des mesures in situ ont ete couplees avec des mesures en conditions semi-controlees.
Innovation systems and farmer perceptions regarding conservation agriculture in Cabo Delgado, Mozambique

Recent research and development efforts within East and Southern Africa, as a case in point, have clearly shown that constraints to adoption of conservation agriculture (CA) can be overcome but stress the need for local innovation systems that involve farmers exchanging among themselves and use of participatory methods that help to adapt CA principles to local conditions. This chapter explores one such innovation system using a district in Cabo Delgado, Mozambique, as a case study. The aims of the chapter are twofold: firstly, to describe the process of construction of the innovation system, and by way of actors' perceptions of the system, to better understand key components central to its formation and functioning; and secondly, to explore farmers' perceptions of CA (including motivation to comply with certain actors in the innovation system) and the effectiveness of the current innovation system in reaching its target beneficiary - the very poor.
Improved estimates of ocean heat content from 1960 to 2015

A new assessment of how much heat Earth has accumulated since 1960 is made by examining ocean heat content changes. Earth’s energy imbalance (EEI) drives the ongoing global warming and can best be assessed across the historical record (that is, since 1960) from ocean heat content (OHC) changes. An accurate assessment of OHC is a challenge, mainly because of insufficient and irregular data coverage. We provide updated OHC estimates with the goal of minimizing associated sampling error. We performed a subsample test, in which subsets of data during the data-rich Argo era are colocated with locations of earlier ocean observations, to quantify this error. Our results provide a new OHC estimate with an unbiased mean sampling error and with variability on decadal and multidecadal time scales (signal) that can be reliably distinguished from sampling error (noise) with signal-to-noise ratios higher than 3. The inferred integrated EEI is greater than that reported in previous assessments and is consistent with a reconstruction of the radiative imbalance at the top of atmosphere starting in 1985. We found that changes in OHC are relatively small before about 1980; since then, OHC has increased fairly steadily and, since 1990, has increasingly involved deeper layers of the ocean. In addition, OHC changes in six major oceans are reliable on decadal time scales. All ocean basins examined have experienced significant warming since 1998, with the greatest warming in the southern oceans, the tropical/subtropical Pacific Ocean, and the tropical/subtropical Atlantic Ocean. This new look at OHC and EEI changes over time provides greater confidence than previously possible, and the data sets produced are a valuable resource for further study.
A community health promotion project: Amazing Race for Heart Health

Introduction American Indians have higher rates of cardiovascular disease (CVD), likely due to disproportionate burden of diabetes and limited access to widespread CVD prevention programs such as Honoring the Gift of Heart Health (HGHH), a 10-week CVD risk factor awareness curriculum. Due to its length, HGHH may be difficult to complete; therefore, we aimed to evaluate a shortened CVD risk factor awareness program based on the HGHH educational materials for American Indians residing in southwest Oklahoma, entitled “The Amazing Race for Heart Health. ” Methods We conducted an interventional study where each participant served as their own control (n = 61), with pre- and post-intervention measurements. We included American Indians from seven tribal nations in southwest Oklahoma. At two interventional meetings we used educational materials and activities from HGHH focusing on nutrition, cholesterol, diabetes, hypertension, physical activity, and heart attack warning signs. McNemar's test was used to determine the effectiveness of the intervention on raising CVD risk factor awareness. Results When comparing the pre- and post-survey responses, the percentage of correct responses either stayed the same or increased. Knowledge improved in 11/25 (44%, p < 0.05) domains including the difference between good and bad cholesterol and types of physical activity that can prevent CVD. When considering diabetes, knowledge increased regarding the interaction between diabetes and cholesterol in the association with CVD. Discussion These results demonstrate that the “Amazing Race for Heart Health,” a shortened CVD risk factor educational program based on the HGHH educational materials, was effective at increasing awareness regarding CVD risk factors.
Karyotype and reproductive traits of the unique symbiotic mealybug Orbuspedummachinator G.-Z. (Homoptera, Coccinea)

﻿Abstract The karyotype and reproductive features of Orbuspedummachinator Gavrilov-Zimin, 2017 (Pseudococcidae) were studied for the first time. Diploid chromosome number is 18 in females. Reproduction is probably bisexual, as indicated by the presence of characteristic Lecanoid heterochromatinization of the paternal set of chromosomes in embryonic cells of about 50% of the embryos studied. The female reproductive system has a pair of lateral oviducts merged into enlarged common oviduct; the spermatheca and accessory glands are connected to the common oviduct in its proximal part. Complete ovoviviparity occurs in ontogenesis.
SCUNLP-2 at the NTCIR-17 FinArg-1 Task: Enhancing Argumentative Relationship Recognition in the Classification Model with Language Generation Model Prompts

While argument mining has significantly advanced across various domains, its application to financial discussions remains relatively unexplored. Our motivation for this research is rooted in the understanding that sentiment analysis alone may be inadequate when evaluating financial discussions, as the financial world is influenced by many factors intricately intertwined with the sentiments and opinions expressed by investors, analysts, and policymakers. To enhance the analysis of financial arguments, we incorporate GPT into the field of financial argument mining and design custom prompts. This unique integration allows us to generate labels and summaries for the arguments extracted from social media discussions. Our research results indicate that adding the generated labels in the regular mode achieved the highest validation set Marco-F1 score (66.39%). These findings contribute to a deeper understanding of argument mining in financial and social media discussions.
NeuroEvolution of Capsule Networks for Computer-Aided Laparoscopy

Of an order of 330 million surgeries are performed worldwide every year. Yet there is a backlog of around 150 million pending surgeries annually. Surgical robotics is becoming a lot more sophisticated by the day. Much of this increasing success is due to advances in Computer Vision (CV) . CV allows the tracking of tools, detection of organs, and a description of the phase of surgery that enables a surgeon to perform the delicate art of surgery with much greater precision and eﬃciency. These advancements have also enabled remote robotic surgery in which a patient and the surgeon can be far apart from each other geographically. In this paper, we report promising results of evolving the architecture of capsule networks for tool classiﬁcation for Computer-Aided Laparoscopy (CAL).
Automatic Urban Modelling using Mobile Urban LIDAR Data

Recent advances in Light Detection and Ranging (LIDAR) technology and integration have resulted in vehicle-borne platforms for urban LIDAR scanning, such as Terrapoint Inc.’s TITAN R © system. Such technology has lead to an explosion in ground LIDAR data. The large size of such mobile urban LIDAR data sets, and the ease at which they may now be collected, has shifted the bottleneck of creating abstract urban models for Geographical Information Systems (GIS) from data collection to data processing. While turning such data into useful models has traditionally relied on human analysis, this is no longer practical. This thesis outlines a methodology for automatically recovering the necessary information to create abstract urban models from mobile urban LIDAR data using computer vision methods. As an integral part of the methodology, a novel scalebased interest operator is introduced (Difference of Normals) that is efficient enough to process large datasets, while accurately isolating objects of interest in the scene according to real-world parameters. Finally a novel localized object recognition algorithm is introduced (Local Potential Well Space Embedding), derived from a proven global method for object recognition (Potential Well Space Embedding). The object recognition phase of our methodology is discussed with these two algorithms as a focus. i
palatogenesis and its fine-tuned expression

Birth defects have always been one of the most important diseases in medical research as they affect the quality of the birth population. Orofacial clefts (OFCs) are common birth defects that place a huge burden on families and society. Early screening and prevention of OFCs can promote better natal and prenatal care and help to solve the problem of birth defects. OFCs are the result of genetic and environmental interactions; many genes are involved, but the current research has not clarified the specific pathogenesis. The mouse animal model is commonly used for research into OFCs; common methods of constructing OFC mouse models include transgenic, chemical induction, gene knockout, gene knock-in and conditional gene knockout models. Several main signal pathways are involved in the pathogenesis of OFCs, including the Sonic hedge-(cid:35)(cid:42)(cid:34)(cid:1)(cid:515)(cid:20)(cid:9)(cid:9)(cid:516)(cid:1)(cid:28)(cid:41)(cid:31)(cid:1)(cid:47)(cid:45)(cid:28)(cid:41)(cid:46)(cid:33)(cid:42)(cid:45)(cid:40)(cid:36)(cid:41)(cid:34)(cid:1)(cid:34)(cid:45)(cid:42)(cid:50)(cid:47)(cid:35)(cid:1)(cid:33)(cid:28)(cid:30)(cid:47)(cid:42)(cid:45)(cid:1)(cid:515)(cid:21)(cid:8)(cid:7)(cid:516)(cid:507)(cid:852)(cid:1)(cid:43)(cid:28)(cid:47)(cid:35)(cid:50)(cid:28)(cid:52)(cid:46)(cid:484)(cid:1)(cid:21)(cid:35)(cid:32)(cid:1)(cid:34)(cid:32)(cid:41)(cid:32)(cid:46)(cid:1)(cid:28)(cid:41)(cid:31)(cid:1)(cid:43)(cid:45)(cid:42)(cid:47)(cid:32)(cid:36)(cid:41)(cid:46)(cid:1)(cid:36)(cid:41)(cid:1)(cid:32)(cid:28)(cid:30)(cid:35)(cid:1)
Local recurrence in rectal cancer : mechanisms of development, patterns of relapse and treatment options

Purpose: Differences exist between Japan and the Netherlands in the treatment of low rectal cancer. The purpose of this study is to analyze these, with focus on the patterns of local recurrence. Methods: In the Netherlands 755 patients were operated by total mesorectal excision (TME) for low rectal cancer, 379 received preoperative radiotherapy (RT+TME). Applying the same selection-criteria resulted in 324 patients in the Japanese (NCCH) group, who received extended surgery consisting of a lateral lymph node dissection and a wider abdominoperineal excision. The majority received no (neo)adjuvant therapy. Local recurrence images were examined by a radiologist and a surgeon. Results: 5-year local recurrence rates are 6.9% in the Japanese NCCH group, 5.8% in the Dutch RT+TME group and 12.1% in the Dutch TME group. Recurrence rate in the lateral pelvis is 2.2%, 0.8% and 2.7% in the Japanese, RT+TME group and TME group, respectively. The incidence of presacral recurrences was low in the NCCH group (0.6%), compared to 3.7% and 3.2% in the RT+TME and TME groups. Conclusions: Both extended surgery and RT+TME result in good local control, as compared to TME alone. Preoperative radiotherapy can sterilize lateral extra-mesorectal tumor particles. A wider APR probably results in less presacral local recurrence. Comparison of the results is difficult because of differences in patient groups.
MIT Open Access Articles RANGE - Robust autonomous navigation in GPS-denied environments

—This video highlights our system that enables a Micro Aerial Vehicle (MAV) to autonomously explore and map unstructured and unknown GPS-denied environments. While mapping and exploration solutions are now well-established for ground vehicles, air vehicles face unique challenges which have hindered the development of similar capabilities. Although there has been recent progress toward sensing, control, and navigation techniques for GPS-denied ﬂight, there have been few demonstrations of stable, goal-directed ﬂight in real-world environments. Our system leverages a multi-level sensing and control hierarchy that matches the computational complexity of the component algorithms with the real-time needs of a MAV to achieve autonomy in unconstrained environments.
Towards Immersive Computational Storytelling:Card-Framework for Enhanced Persona-Driven Dialogues

In the realm of RPGs, creating immersive, persona-driven dialogues remains a challenge, especially in intricate settings like Call of Cthulhu (CoC). Existing methodologies often falter in portraying character personas within complex conversations accurately. To address this, we introduce a novel card-based framework, utilizing the advanced Baichuan-7B language model for tailored dialogue generation. Guided by detailed scene settings and character personas, Baichuan-7B exhibited a striking ability to craft context-aware dialogues for even unseen characters and scenarios. To assess the quality of these dialogues, we present an innovative metric, circumventing the traditional hurdles of human evaluations. Furthermore, insights into the attention mechanism shed light on the dynamics of information ﬂow during dialogue creation. Collectively, our ﬁndings underscore the transformative potential of large language models in computational storytelling, particularly in RPG settings. ˆA
2017 , Overstretching of B-DNA with various pulling protocols: Appearance of structural polymorphism and S-DNA

We report a structural polymorphism of the S-DNA when a canonical B-DNA is stretched under diﬀerent pulling protocols and provide a fundamental molecular understanding of the DNA stretching mechanism. Extensive all atom molecular dynamics simulations reveal a clear formation of S-DNA when the B-DNA is stretched along the 3 ′ directions of the opposite strands (OS3) and is characterized by the changes in the number of H-bonds, entropy and free energy. Stretching along 5 ′ directions of the opposite strands (OS5) leads to force induced melting form of the DNA. Interestingly, stretching along the opposite ends of the same strand (SS) leads to a coexistence of both the S-and melted M-DNA structures. We also do the structural characterization of the S-DNA by calculating various helical parameters. We ﬁnd that S-DNA has a twist of ∼ 10 degrees which corresponds to helical repeat length of ∼ 36 base pairs in close agreement with the previous experimental results. Moreover, we ﬁnd that the free energy barrier between the canonical and overstretched states of DNA is higher for the same termini (SE) pulling protocol in comparison to all other protocols considered in this work. Overall, our observations not only reconcile with the available experimental results qualitatively but also enhance the understanding of diﬀerent overstretched DNA structures.