Miracle-dz/UniFAR-FTUs huggingface dataset:
Ionic Liquid-Coordinated Ferrous Acetate Complex Immobilized on Bentonite As a Novel Separable Catalyst for PET Glycolysis

Ionic liquid-coordinated ferrous acetate complex immobilized on bentonite ([Bmim—Fe][(OAc)3]/bentonite) was prepared by impregnation of [Bmim—Fe][(OAc)3] on bentonite. The prepared catalyst was characterized using FTIR, XRD and total carbon (TC). The catalyst showed a high catalytic activity in the glycolysis of polyethylene terephthalate (PET) under mild condition. Maximum activity was observed with a PET conversion of 100% and bis(2-hydroxyethyl)terephthalate (BHET) yield of 44% under the optimum conditions of catalyst (1.0 g), ethylene glycol (20 g) and PET (3.0 g) at 190 °C for 3 h. The activation energy of PET glycolysis using the prepared catalyst was calculated and found to be 51.6 kJ/mol.
The Use of Virtual Reality Technologies to Reduce Anxiety and Improve Experience in Chemotherapy Patients During Treatment

The study explored the potential benefits of virtual reality as a psychological intervention to induce positive emotions and reduce pain levels in participants receiving IV chemotherapy treatment. Participants in the study had the opportunity to select a nature theme of their choosing during their treatment session. The study provided a noninvasive solution that promoted relaxation to reduce anxiety by shifting an individual’s mood positively during treatment. The objective was met by measuring participants' mood and pain levels before and after the virtual reality experience and participant satisfaction with the use of the technology. The study was conducted in the chemotherapy treatment area at the INTEGRIS Cancer Institute and consisted of a mixed demographic of cancer diagnosed patients. Results of this study showed that participants felt more calm, relaxed, and content, as well as less tense after the use of VR. Participants showed high ratings of feeling immersed and distracted by feeling like they were visiting the places displayed and paid more attention to the said environment than their own thoughts. There was no significant difference in blood pressure, pain levels, feeling upset, or worried. A majority of participants preferred to have VR as part of their future experiences during treatment time.
Massively Multiplayer Online Games and Well-Being: A Systematic Literature Review

Background: Massively multiplayer online games (MMOs) evolve online, whilst engaging large numbers of participants who play concurrently. Their online socialization component is a primary reason for their high popularity. Interestingly, the adverse effects of MMOs have attracted significant attention compared to their potential benefits. Methods: To address this deficit, employing PRISMA guidelines, this systematic review aimed to summarize empirical evidence regarding a range of interpersonal and intrapersonal MMO well-being outcomes for those older than 13. Results: Three databases identified 18 relevant English language studies, 13 quantitative, 4 qualitative and 1 mixed method published between January 2012 and August 2020. A narrative synthesis methodology was employed, whilst validated tools appraised risk of bias and study quality. Conclusions: A significant positive relationship between playing MMOs and social well-being was concluded, irrespective of one's age and/or their casual or immersed gaming patterns. This finding should be considered in the light of the limited: (a) game platforms investigated; (b) well-being constructs identified; and (c) research quality (i.e., modest). Nonetheless, conclusions are of relevance for game developers and health professionals, who should be cognizant of the significant MMOs-well-being association(s). Future research should focus on broadening the well-being constructs investigated, whilst enhancing the applied methodologies.
Combined Effects of Water and Nitrogen on Growth, Biomass, and Quality of Spinach (Spinacia oleracea Linn.)

ABSTRACT Water scarcity and nitrate contamination have caused considerable attention to environmental matters. Water and nitrogen interactions have critical impacts on their use efficiency, plant growth, and quality. In a field experiment, a combination of three water treatments and three nitrogen rates was applied to determine their interactive effects on the growth of spinach. Soil water supply that was too low [W3N1 (the combination of water treatment 3 and nitrogen treatment 1), W3N2] could cause an increase in nitrate content. Oxalate contents would increase when water and nitrogen were either inadequate (W3N0, W3N1) or too high (W2N2). The most profit from spinach was obtained in plots that received water treatment 2 and nitrogen fertilizer 78 kg N ha−1. However, considering nitrogen treatments could affect the nitrate and oxalic acid, application of water treatment 2 and 39 kg N ha−1 nitrogen fertilizer could get better spinach quality.
A Prospective Study on Fertility Preservation in Prepubertal and Adolescent Girls Undergoing Hematological Stem Cell Transplantation

Background Hematological stem cell transplantation (HSCT) is an established method which has markedly increased the survival rate of hematologic malignancies since its introduction in the 1980’s. The conditioning for HSCT has known gonadotoxic effects and often leads to premature loss of fertility. In this study we have prospectively followed a cohort of girls undergoing HSCT and studied the outcomes of fertility preservation treatments performed before or after HSCT, as well as the long-term reproductive outcome. Methods In this one-center prospective study, 39 girls counselled for fertility preservation prior to or after conditioning for HSCT for malignant or benign diseases at childhood or adolescence between 1990 and 2017 were included. The patients were presented with the option to undergo cryopreservation of ovarian tissue or oocytes depending on their age and the time available. Follicle counts of the ovarian tissue and number of oocytes collected before or after HSCT were compared between patients treated for benign and malignant diseases. Hormone measurements post HSCT treatment, including FSH and AMH, reproductive outcomes and overall survival until January 2021 were investigated. Results In total, 34 girls and adolescents underwent fertility preservation before or after HSCT. Before HSCT, ovarian tissue was cryopreserved in 15 patients and two patients had oocytes preserved. Thirteen patients cryopreserved ovarian tissue after HSCT and seven patients returned to cryopreserve oocytes. Follicles were present in all tissue samples collected prior to HSCT, and in more than half of the samples collected post-HSCT. Half of the patients had spontaneous menarche or resumed menstruation post HSCT. Overall, 35 patients had survived at end of follow up and 7 patients had achieved parenthood. Conclusions Since fertility loss is common following HSCT, fertility preservation should be offered to all patients. Fertility preservation treatments can be performed both before and after HSCT. Clinical Trial Registration https://clinicaltrials.gov/show/NCT04602962, identifier NTC04602962
Controls on the physics and chemistry of seafloor hydrothermal circulation

Low temperature diffuse hydrothermal circulation is a natural consequence of the cooling of the oceanic lithosphere. Diffuse flow is expected to be ubiquitous, and will be present both within mid–ocean ridge crest axial zones of young age (0–1 Ma), and also on the older ridge crest flanks and limbs. If underlying thermal models are correct, hydrothermal circulation should persist for oceanic lithosphere of age 0–65 Ma, and is present over half the total area of the ocean basins. By using numerical models of hydrothermal circulation in cracked permeable media, we show qualitatively how diffuse flow is an intrinsic feature of high temperature axial (–1 Ma) hydrothermal systems, and is not restricted to older (more than 1 Ma) lithosphere. This is in agreement with our field observations which suggest that in such high temperature vent fields the greatest part of the heat and volume flux is due to lower temperature diffuse flow, rather than high temperature black smoker venting. By combining direct measurements of the physical properties of diffusely flowing effluent within axial hydrothermal systems with concurrent sampling of the chemical properties of that effluent, and by considering also the chemistry of unmixed black smoker endmember fluids from the same hydrothermal systems, the processes of mineral deposition and dissolution can be studied directly. By referring to the present–day lithology of such areas, it is possible to examine the balance between concurrent mineral deposition and dissolution processes, and the retention rate of specific mineral assemblages integrated over the history of the hydrothermal system. Thus details of the episodicity of hydrothermal venting within the system may be revealed. An example of this method of combining a variety of direct measurements of diffuse and high temperature effluent properties is given from the TAG hydrothermal field, Mid–Atlantic Ridge. Long time series observations of the physical properties of diffuse and high temperature effluent reveal the importance both of tidal variability and also the response to changes in the permeability structure of the system brought about by natural and anthropogenic processes. Several mechanisms are considered to explain the relationship between ocean tidal loading, solid Earth tidal deformations, and the observed changes in flow within axial hydrothermal systems.
Labelfreie Detektion von Protein-DNA-Interaktionen durch elektrochemische Impedanzspektroskopie

Es wird ein impedimetrisches Sensorsystem fur den Nachweis von Protein-DNA-Wechselwirkungen vorgestellt. Der Sensor nutzt kurze Thiol-markierte DNA (ssDNA), die uber Chemisorption auf Goldchipelektroden immobilisiert wird. Aus den Impedanzspektren wurde der Durchtrittswiderstand (Rct) als Kenngrose fur die zu untersuchenden Wechselwirkungen gewahlt. In Anwesenheit des Redoxsystems Ferro-/Ferrycyanid konnte eine Zunahme des Durchtrittswiderstandes nach der Immobilisierung und anschliesender Hybridisierung auf der Sensoroberfl ache registriert werden. Der Einsatz langerer Fanger-DNA (25- mer im Vergleich zu 18-mer) fuhrte zu einer Abnahme der Konzentration an immobilisierten Fanger-Strangen, aber auch zu einer Vergroserung der Durchtrittswiderstande sowohl fur ssDNA als auch dsDNA. Bei ahnlichen Oberflachenkonzentrationen lies sich eine annahernd gleiche Sensitivitat des Hybridisierungsnachweises im Vergleich zu 18-mer Fanger-Strangen erzielen. Mit Hilfe des Elektrodensystems wurde die Nachweisbarkeit von Protein-DNA-Wechselwirkungen untersucht. Die Restriktion doppelstrangiger DNA durch die Restriktionsendonuklease BamHI konnte mit der Zyklovoltammetrie und markierungsfrei mit der Impedanzspektroskopie verfolgt werden. Des Weiteren wurde die sequenzspezifische Bindung des Transkriptionsfaktors NF-κB p50 an
Effects of Tolerance and Enrichment Characteristics of Cyperus iria L. to Uranium under Hydroponic and Potted Culture

A hydroponic and potted experiment was conducted to investigate the tolerance ability and characteristics of enrichment of uranium by Cyperus iria L. The results showed that: 1) The enrichment characteristics of uranium by C. iria depended on multiple factors including the uranium concentration in water or soil and the growth stages of the plants. The uranium content in the roots and stems and leaves increased as the concentration of uranium increased. After exposure to uranium solutions for 30 days, the uranium concentrations( dry weight) in its roots ranged between( 4,158 ±611) mgkg for 100 mgL uranium solution and( 48,605 ± 1,266)mgkg for 2,500 mgL uranium solution. The uranium concentrations in its shoots ranged between( 366 ± 26) mgkg for100 mgL uranium solution and( 8,224 ± 856) mgkg for 2,500mgL solution concentration; these were only 1 10-1 5 of those in the shoots. Except grade of growth inhibition,all the growthparameters had the similar tendency: they would come to a peak at the initial concentration of uranium between 100 mgL and 250 mgL and then steadily decline with a sharp decrease between 500 and 2,500 mgL. 2) There was a strong adaptability and tolerance of C. iria on the uranium tailing,the biological enrichment coefficients( BC) in shoot cannot always be greater than 1. The uranium content in the shoots of C. iria was higher in flowering stage than seeding stage,and the value of BC in shoot was increased when adding citric acid to the uranium tailing in the seeding stage.
The prognostic significance of different proportion of signet-ring cells of colorectal carcinoma

While the prognosis of patients with partial signet-ring cell carcinoma (PSRCC) has been rarely reported, colorectal signet-ring cell carcinoma (SRCC) has been associated with poor prognosis. The aim of this study was to analyze the prognosis of patients with different signet-ring cell (SRC) composition and establish a prediction model. A total of 91 patients with SRC component were included in the study. These patients were divided into two groups: SRCC group (SRC composition >50%; n = 41) and PSRCC group (SRC composition ≤50%; n = 50). COX regression model was used to identify independent prognostic factors for overall survival (OS). A predictive nomogram was established and compared with the 7th American Joint Committee on Cancer (AJCC) staging system. After a median follow-up of 16 months, no significant difference in OS was observed in either group. Pre-operative carcinoembryonic antigen level, pN stage, M stage, pre-operative ileus, and adjuvant chemotherapy were independent prognostic risk factors for OS (p < 0.05). A nomogram for predicting the OS of colorectal SRCC was established with a C-index of 0.800, and it showed better performance than that of the 7th AJCC staging system (p < 0.001). In summary, the ratio of SRC component was not an independent prognostic factor of the OS. Those patients with <50% of SRC component should be given the same clinical attention. A predictive nomogram for survival based on five independent prognostic factors was developed and showed better performance than the 7th AJCC staging system. This resulted to be helpful for individualized prognosis prediction and risk assessment.
SoK: Applying Blockchain Technology in Industrial Internet of Things

—The proliferation of the Internet of Things (IoT) technology has made ubiquitous computing a reality by broadening Internet connectivity across diverse application domains, thus bridging billions of devices and human beings as well for information collection, data processing, and decision-making. In recent years, IoT technology and its applications in various industrial sectors have grown exponentially. Most existing industrial IoT (IIoT) implementations, however, are still relying on a centralized architecture, which is vulnerable to the single point of failure attack and requires a massive amount of computation at the central entity. The emerging blockchain technology is currently undergoing rapid development and has the full potential to revolutionize the IIoT platforms and applications. As a distributed and decentralized tamper-resistant ledger, blockchain maintains the consistency of data records at different locations and holds the potential to address the issues in traditional IIoT networks, such as heterogeneity, interoperability, and security. Integrating the blockchain technology into IIoT platforms requires to address several critical challenges that are inherent in IIoT and blockchain themselves, such as standardization, scalability, and interoperability. This paper provides a comprehensive review on the recent advances in architecture design and technology development towards tackling these challenges. We further provide several representative industrial use cases that can beneﬁt from the integration of blockchain technology, and discuss the recent research trends and open issues in blockchain-enabled IIoT platforms.
Compact Miniaturized Bioluminescence Sensor Based on Continuous Air-Segmented Flow for Real-Time Monitoring: Application to Bile Salt Hydrolase (BSH) Activity and ATP Detection in Biological Fluids

A simple and versatile continuous air-segmented flow sensor using immobilized luciferase was designed as a general miniaturized platform based on sensitive biochemiluminescence detection. The device uses miniaturized microperistaltic pumps to deliver flows and compact sensitive light imaging detectors based on BI-CMOS (smartphone camera) or CCD technology. The low-cost components and power supply make it suitable as out-lab device at point of need to monitor kinetic-related processes or ex vivo dynamic events. A nylon6 flat spiral carrying immobilized luciferase was placed in front of the detector in lensless mode using a fiber optic tapered faceplate. ATP was measured in samples collected by microdialysis from rat brain with detecting levels as low as 0.4 fmoles. The same immobilized luciferase was also used for the evaluation of bile salt hydrolase (BSH) activity in intestinal microbiota. An aminoluciferin was conjugatated with chenodeoxycholic acid forming the amide derivative aLuc-CDCA. The hydrolysis of the aLuc-CDCA probe by BSH releases free uncaged aminoluciferin which is the active substrate for luciferase leading to light emission. This method can detect as low as 0.5 mM of aLuc-CDCA, so it can be used on real faecal human samples to study BSH activity and its modulation by diseases and drugs.
Reinforcement Learning-Based Television White Space Database

Television white spaces (TVWSs) refer to the unused part of the spectrum under the very high frequency (VHF) and ultra-high frequency (UHF) bands. TVWS are frequencies under licenced primary users (PUs) that are not being used and are available for secondary users (SUs). There are several ways of implementing TVWS in communications, one of which is the use of TVWS database (TVWSDB). The primary purpose of TVWSDB is to protect PUs from interference with SUs. There are several geolocation databases available for this purpose. However, it is unclear if those databases have the prediction feature that gives TVWSDB the capability of decreasing the number of inquiries from SUs. With this in mind, the authors present a reinforcement learning-based TVWSDB. Reinforcement learning (RL) is a machine learning technique that focuses on what has been done based on mapping situations to actions to obtain the highest reward. The learning process was conducted by trying out the actions to gain the reward instead of being told what to do. The actions may directly affect the rewards and future rewards. Based on the results, this algorithm effectively searched the most optimal channel for the SUs in query with the minimum search duration. This paper presents the advantage of using a machine learning approach in TVWSDB with an accurate and faster-searching capability for the available TVWS channels intended for SUs.
“There will be consequences!” Datasets and Benchmarks towards Causal Relation Extraction and Societal Event Forecasting

In this paper, we discuss the creation of datasets (from which future benchmarks 1 and other derived datasets can be created), geared towards causal relation extraction 2 from a given context (obtained from the Google Natural Questions dataset) and 3 event forecasting, especially that of making predictions of effects of societal events 4 based on past iterations of similar events and more, obtained from Wikipedia 5 and WikiNews. We introduce multiple novel datasets in this work:- 1. ) Four 6 named versions of benchmarks towards extracting verbatim phrasal causes and 7 effects based on contextual than commonsense reasoning from Google’s Natural 8 Questions dataset; two being denoted as the ﬁnal set, called the Final Evaluation 9 versions set of the Cause-Effect-Context from Natural Questions (NQ-CE) 2. ) 10 Three datasets of impacts and benchmarks from Wikipedia, so that, given some 11 query event X, we try to answer the question, "what will follow? "; namely for 12 the COVID-19 , 9/11 and the Hurricane Sandy usecases, collectively referred to 13 as the Dataset of Signiﬁcant Societal Events and their Impacts from Wikipedia 14 (SSIW) and two collections of signiﬁcant societal events from Wikipedia year pages, 15 called the Signiﬁcant Societal Events from Wikipedia Year Pages (SSWY) . 3. ) One 16 dataset of events from WikiNews, called the Event Consequence Collections from 17 WikiNews (ECCW); extracting source events, their consequences and relevant 18 and best matching semantically related non consequences for thirty-nine category 19 pages in WikiNews after having ﬁltered them using a combination of automated 20 and manual ﬁltering approaches from over 10k category pages. Future work, 21 including evaluating benchmarks and creating datasets with more categories and 22 types of events, along with creating derived benchmarks from any created datasets 23 is planned. 24
Biophysical characterization of non-motor contractility of actin cytoskeleton

Cytokinesis is the final step of cell division during which the maternal cell is physically divided into two daughter cells. The success of the cytokinesis relies on the formation of the contractile ring composed of acto-myosin cytoskeleton. The ring produces the force required for the cleavage of the maternal cell. Despite the broadly accepted assumption that myosin motors are responsible for the actin contractility, in some cells, however, the ring contracts even when the activity of myosin is restricted. The aim of this thesis was to test the hypothesis that actin contractility can be propelled by diffusible nonmotor actin crosslinker anillin. We used reconstituted actin filaments and anillin in vitro to study minimal models of actin contractility in the absence of myosin. Using TIRF microscopy, we showed directional sliding of overlapping actin filaments and constriction of actin-anillin rings. Our results show that anillin is a diffusive crosslinker of actin filaments that may contribute to actin contractility.
Effect Of Education In Preventing Diabetic Foot Ulcers To Compliance And Quality Of Life The Diabetic Patients

Objective of the research was to find out the influence of education in preventing foot ulcers on compliance in DM Type 2 patients. Material and Methods: the research used quasi-experimental method with pretest-posttest control group design. It was done at USU Hospital from July to August, 2019. The samples were 43 DM Type 2 patients in control and intervention grouprespectively, taken by using convenience sampling technique. The data were analyzed by using Wilcoxon statistic test. Result: the result showed that there was the influence of education in preventing diabetic foot ulcers (p<0.05) on the level of patients’ compliance. Conclusion: Education in preventing diabetic foot ulcers was done to increase compliance in DM patients to prevent more complication and to increase the quality of life the diabetic patients.