Miracle-dz/UniFAR-FTUs huggingface dataset:
Dynamic Portfolio Optimization with Transaction Costs and State-Dependent Drift

The problem of dynamic portfolio choice with transaction costs is often addressed by constructing a Markov Chain approximation of the continuous time price processes. Using this approximation, we present an efficient numerical method to determine optimal portfolio strategies under time- and state-dependent drift and proportional transaction costs. This scenario arises when investors have behavioral biases or the actual drift is unknown and needs to be estimated. Our numerical method solves dynamic optimal portfolio problems with an exponential utility function for time-horizons of up to 40 years. It is applied to measure the value of information and the loss from transaction costs using the indifference principle.
Dimensions of inequality: facts on the U.S. distributions of earnings, income, and wealth

This article describes some facts about financial inequality in the United States that a good theory of inequality must be able to explain. These include the facts that labor earnings, income, and wealth are all unequally distributed among U.S. households, but the distributions are significantly different. Wealth is much more concentrated than the other two. Wealth is positively correlated with earnings and income, but not strongly. The movement of households up and down the economic scale is greater when measured by income than by earnings or wealth. Differences across the three variables remain when the data are disaggregated by age, employment status, educational level, and marital status of the heads of U.S. households. Each of these classifications also has significant differences across households. All the facts are based on data taken from the 1992 Survey of Consumer Finances and the 1984‐85 and 1989‐90 Panel Study of Income Dynamics.
Functional Analysis A generalization of the Friedrichs angle and the method of alternating projections

We present a generalization to an arbitrary number of subspaces of the cosine of the Friedrichs angle between two subspaces of a Hilbert space. This parameter is used to analyze the rate of convergence in the von NeumannHalperin method of alternating projections. To cite this article: C. Badea, S. Grivaux, V. Müller, C. R. Acad. Sci. Paris, Ser. I ***(****). Résumé Une généralisation de l’angle de Friedrichs et la méthode des projections alternées. On considère une généralisation à plusieurs espaces du cosinus de l’angle de Friedrichs entre deux sous-espaces d’un espace de Hilbert. On utilise ce paramètre pour analyser la vitesse de convergence dans la méthode des projections alternées de von Neumann-Halperin. Pour citer cet article : C. Badea,S. Grivaux, V. Müller, C. R. Acad. Sci. Paris, Ser. I ***(****).
University of Birmingham Influence of temperature and pressure on surface modified Pd-Cu alloy foils for hydrogen purification applications

The surface of as-received Pd60Cu40 wt% foil samples was modified by depositing a Pd thin film onto one side. X-ray diffraction analysis revealed that the as-received Pd60Cu40 wt% foil contained only the disordered face centred cubic (FCC) phase. Three different Pd thin film thicknesses (100, 800 and 1,400 nm) were deposited using magnetron sputtering onto the as-received Pd60Cu40 wt% foil to produce the surface modified foil samples. X-ray diffraction and X-ray photoelectron spectroscopy analysis of these samples showed a strong indication that Cu interdiffusion occurred between the bulk Pd-Cu foil and Pd thin film during the deposition process. For the first time, variable temperature X-ray diffraction analysis has been performed on the surface modified foil samples between 30 and 700 °C under 100 and 445 kPa of hydrogen pressure in order to investigate the effects of these conditions on Cu interdiffusion. In general, it was found that under 445 kPa of hydrogen pressure the palladium hydride (β-PdH) phase present in the thin film is stable up to higher temperatures (225 °C) than under 100 kPa of hydrogen pressure (150 to 175 °C). In all cases, it was observed that the interstitial solid solution (α-PdH) phase present within the thin film is stable under a significantly narrower temperature range under 445 kPa of hydrogen pressure when compared to 100 kPa.
Oceanic control of the warming processes in the Arctic - a different point of view for the reasons of changes in the Arctic climate

The paper describes the strong correlation between the sea surface temperature (SST) in the region of the Gulf Stream delta and anomalies in surface air temperature (SAT) in the Arctic over the period 1880-2007. This correlation results from the transfer of a variable amount of heat from the Atlantic tropics into the Arctic through oceanic circulation (AMO – Atlantic Multidecadal Oscillation). Reaction of sea ice is the main mechanism controlling the heat content in water carried to the Arctic and influencing the SAT. Sea ice may either increase or limit the heat flow from the ocean to the atmosphere. The genesis of the ‘Great warming of the Arctic’ in the 1930s and ‘40s is the same as that of the present day. Both may be considered to be attributable to natural processes and are not demonstrably associated in any way with a supposed ‘Global greenhouse effect’. Changes in the concentration of CO2 in the atmosphere could only explain 9% of variations in the SAT in the Arctic.
ROLE OF SERUM IRON AND ITS ASSOCIATION WITH ANEMIC PREVALANCE AMONG PATIENTS WITH DIFFERENT TYPE OF CANCER

Cancer is a group of diseases in which cells are aggressive, invasive and sometimes metastatic. Nutritional status an important factor that contributes to immune competence for which trace minerals plays a crucial role in the biochemical and physiological activity of the system. Trace element a category of minerals essential for the biological system and plays an active role in immune effector mechanism. Normal range of iron essential for body metabolism, iron deficiencies leads to anemia which might complicate the event of tumor genesis. Study involved 50 volunteers (36 females, 14 males) of cancer patients of Mohan Nursing Home Madurai. Serum was collected in the informed consent of the patients. Serum iron level was quantified using Atomic Absorption Spectrophotometer. Study documented percentage deviation of serum iron concentration (85%) with severe anemic prevalence from the control individual (without cancer) and also establish an association of iron deficiency with anemic prevalence. Study documented the existence of Iron deficiency which is the most common cause of anemia worldwide. Iron plays a role in oxygen transfer in cytochromes, protein molecules involved in the production of energy in cells and also exhibit certain properties to facilitate antitumor status. Study concludes that serum iron modulations need to be emphasized to minimize the burdenization of the host with Clinical associated complications of Iron deficiency among patients with cancer.
2 The Impact of CBI ’ s on Daily Realized FX Moments 2 . 1

This paper studies and assesses the impact of G3 Central Bank interventions on the DEM/USD exchange rate properties using daily realized moments of exchange rate returns (obtained from intraday data) for the period 1989-2001. Boxplots of the realized moments for the intervention day, the days preceding and following the intervention day illustrate the shape of this impact. Rolling regressions results for an ARFIMA model for realized moments are used to measure the intervention impact and characterize its significance. Our analysis allows to confirm previous findings but also to highlight new ones including the timing and the persistence of coordinated interventions on exchange rate volatility, important volatility spillovers, impact on exchange rate cross-moments like covariance and correlation as well as significant responses in terms of realized skewness. JEL Classifications: C22, E44, F31, G15.
Hanna Poikonen ( 1 ) Petri Toiviainen ( 2 ) Mari Tervaniemi ( 1 , 3 ) Dance on Cortex : Enhanced Theta Synchrony in Experts when Watching a Dance Piece

All material supplied via JYX is protected by copyright and other intellectual property rights, and duplication or sale of all or part of any of the repository collections is not permitted, except that material may be duplicated by you for your research use or educational purposes in electronic or print form. You must obtain permission for any other use. Electronic or print copies may not be offered, whether for sale or otherwise to anyone who is not an authorised user. Dance on Cortex : Enhanced Theta Synchrony in Experts when Watching a Dance Piece Poikonen, Hanna; Toiviainen, Petri; Tervaniemi, Mari
Reconstructing Lithic Supply Zones and Procurement Areas: An Example from the Bay of Islands, Northland, New Zealand

While our ability to match lithic artefacts to geological source continues to improve, few explicit techniques exist for the spatial analysis and interpretation of sourced assemblages on the regional level. Obsidian from the Bay of Islands, New Zealand is used here to describe a method of spatial analysis focused on defining intra-regional procurement areas where people accessed a common set of sources. The results suggest future analyses of North Island obsidian should take care to account for the natural accessibility of sources and the use of non-local obsidian among coastal populations with greater access to maritime trade and exchange.
L'orientation client du vendeur du point de vue du consommateur : les apports de la théorie de l'attachement

La litterature en force de vente, essentiellement basee sur des etudes qualitatives menees au cours des annees 80, presente le concept d’orientation relationnelle comme la capacite du vendeur a contribuer a la satisfaction et a la perennisation des relations commerciales. Notre etude vise a revisiter la nature de l’orientation client ou relationnelle des vendeurs sur la base de 67 recits de consommateurs recueillis a l’aide de la methode des incidents critiques. Nous trouvons que l’orientation client est composee de deux facettes : la transmission d’expertise et la creation de lien. Ces comportements relationnels du vendeur semblent jouer un role fondamental dans le processus de satisfaction client et dans la creation de lien. Nous proposons une lecture originale de la construction de ce lien vendeur-client grâce a la theorie de l’attachement.
Implications of Recent Clinical Trials for the National Cholesterol Education Program Adult Treatment Panel III Guidelines

The Adult Treatment Panel III (ATP III) of the National Cholesterol Education Program issued an evidence-based set of guidelines on cholesterol management in 2001. Since the publication of ATP III, 5 major clinical trials of statin therapy with clinical end points have been published. These trials addressed issues that were not examined in previous clinical trials of cholesterol-lowering therapy. The present document reviews the results of these recent trials and assesses their implications for cholesterol management. Therapeutic lifestyle changes (TLC) remain an essential modality in clinical management. The trials confirm the benefit of cholesterol-lowering therapy in high-risk patients and support the ATP III treatment goal of low-density lipoprotein cholesterol (LDL-C) <100 mg/dL. They support the inclusion of patients with diabetes in the high-risk category and confirm the benefits of LDL-lowering therapy in these patients. They further confirm that older persons benefit from therapeutic lowering of LDL-C. The major recommendations for modifications to footnote the ATP III treatment algorithm are the following. In high-risk persons, the recommended LDL-C goal is <100 mg/dL, but when risk is very high, an LDL-C goal of <70 mg/dL is a therapeutic option, ie, a reasonable clinical strategy, on the basis of available clinical trial evidence. This therapeutic option extends also to patients at very high risk who have a baseline LDL-C <100 mg/dL. Moreover, when a high-risk patient has high triglycerides or low high-density lipoprotein cholesterol (HDL-C), consideration can be given to combining a fibrate or nicotinic acid with an LDL-lowering drug. For moderately high-risk persons (2+ risk factors and 10-year risk 10% to 20%), the recommended LDL-C goal is <130 mg/dL, but an LDL-C goal <100 mg/dL is a therapeutic option on the basis of recent trial evidence. The latter option extends also to moderately high-risk persons with a baseline LDL-C of 100 to 129 mg/dL. When LDL-lowering drug therapy is employed in high-risk or moderately high-risk persons, it is advised that intensity of therapy be sufficient to achieve at least a 30% to 40% reduction in LDL-C levels. Moreover, any person at high risk or moderately high risk who has lifestyle-related risk factors (eg, obesity, physical inactivity, elevated triglycerides, low HDL-C, or metabolic syndrome) is a candidate for TLC to modify these risk factors regardless of LDL-C level. Finally, for people in lower-risk categories, recent clinical trials do not modify the goals and cutpoints of therapy.
Peginterferon Alfa-2a plus ribavirin versus interferon alfa-2a plus ribavirin for chronic hepatitis C in HIV-coinfected persons.

BACKGROUND Chronic hepatitis C virus (HCV) infection is a cause of major complications in persons who are also infected with the human immunodeficiency virus (HIV). However, the treatment of HCV infection in such persons has been associated with a high rate of intolerance and a low rate of response. We conducted a multicenter, randomized trial comparing peginterferon plus ribavirin with interferon plus ribavirin for the treatment of chronic hepatitis C in persons coinfected with HIV. METHODS A total of 66 subjects were randomly assigned to receive 180 microg of peginterferon alfa-2a weekly for 48 weeks, and 67 subjects were assigned to receive 6 million IU of interferon alfa-2a three times weekly for 12 weeks followed by 3 million IU three times weekly for 36 weeks. Both groups received ribavirin according to a dose-escalation schedule. At week 24, subjects who did not have a virologic response (those who had an HCV RNA level greater than or equal to 60 IU per milliliter) underwent liver biopsy, and medications were continued in subjects with either a virologic response or histologic improvement. RESULTS Treatment with peginterferon and ribavirin was associated with a significantly higher rate of sustained virologic response (an HCV RNA level of less than 60 IU per milliliter 24 weeks after completion of therapy) than was treatment with interferon and ribavirin (27 percent vs. 12 percent, P=0.03). In the group given peginterferon and ribavirin, only 14 percent of subjects with HCV genotype 1 infection had a sustained virologic response (7 of 51), as compared with 73 percent of subjects with an HCV genotype other than 1 (11 of 15, P<0.001). Histologic responses were observed in 35 percent of subjects with no virologic response who underwent liver biopsy. CONCLUSIONS In persons infected with HIV, the combination of peginterferon and ribavirin is superior to the combination of interferon and ribavirin in the treatment of chronic hepatitis C. These regimens may provide clinical benefit even in the absence of virologic clearance. The marked discrepancy in the rates of sustained virologic response between HCV genotypes indicates that strategies are needed to improve the outcome in persons infected with HCV genotype 1.
Intrapartum exposure to nevirapine and subsequent maternal responses to nevirapine-based antiretroviral therapy.

BACKGROUND A single intrapartum dose of nevirapine for the prevention of mother-to-child transmission of human immunodeficiency virus (HIV) leads to the selection of resistance mutations. Whether there are clinically significant consequences in mothers who are subsequently treated with a nevirapine-containing regimen is unknown. METHODS We randomly assigned 1844 women in Thailand who received zidovudine during the third trimester of pregnancy to receive intrapartum nevirapine or placebo. In the postpartum period, 269 of the women with a CD4 count below 250 cells per cubic millimeter began a nevirapine-containing antiretroviral regimen. Plasma samples were obtained 10 days post partum and analyzed for resistance mutations. Plasma HIV type 1 (HIV-1) RNA was measured before the initiation of therapy and three and six months thereafter. RESULTS After six months of therapy, the HIV-1 RNA level was less than 50 copies per milliliter in 49 percent of the women who had received intrapartum nevirapine, as compared with 68 percent of the women who had not received intrapartum nevirapine (P=0.03). Resistance mutations to nonnucleoside reverse-transcriptase inhibitors were detectable in blood samples obtained 10 days post partum from 32 percent of the women who had received intrapartum nevirapine; the most frequent mutations were K103N, G190A, and Y181C. Among the women who had received intrapartum nevirapine, viral suppression was achieved at six months in 38 percent of those with resistance mutations and 52 percent of those without resistance mutations (P=0.08). An HIV-1 RNA level at or above the median of 4.53 log10 copies per milliliter before therapy and intrapartum exposure to nevirapine were independently associated with virologic failure. After six months of therapy, there was no significant difference between groups in the CD4 count (P=0.65). CONCLUSIONS Women who received intrapartum nevirapine were less likely to have virologic suppression after six months of postpartum treatment with a nevirapine-containing regimen. Our data suggest the need for strategies to maximize the benefits of both antiretroviral prophylaxis against mother-to-child transmission of HIV and antiretroviral therapy for mothers.
"Irrational" searchers and IR-rational researchers

In this article we look at the prescriptions advocated by Web search textbooks in the light of a selection of empirical data of real Web information search processes. We use the strategy of disjointed incrementalism, which is a theoretical foundation from decision making, to focus on how people face complex problems, and claim that such problem solving can be compared to the tasks searchers perform when interacting with the Web. The findings suggest that textbooks on web searching should take into account that searchers only tend to take a certain number of sources into consideration, that the searchers adjust their goals and objectives during searching, and that searchers reconsider the usefulness of sources at different stages of their work tasks as well as their search tasks.
Aalborg Universitet Multiagent System-Based Distributed Coordinated Control for Radial DC Microgrid Considering Transmission Time

This paper focuses on a multi-agent based distributed coordinated control for radial DC microgrid considering transmission time delays. Firstly, a two-level multi-agent system is constructed, where local control is formulated based on local states and executed by means of the first-level agent, and distributed coordinated control law is formulated based on wide-area information and executed by means of the secondarylevel agent in order to improve the voltage control performances. Afterwards, the research mainly focuses on designing the local controller and the distributed coordinated controller. For purpose of robust stability, the local control is designed as local state-feedback based H∞ robust controller. It is worth mentioning that the distributed coordinated control consists of local state feedback control and decoupling coordinated control law that only come from adjacent DER units. Moreover, the distributed coordinated controller is designed by means of delay-dependent H∞ robust control method taking into account transmission time delays. Finally, the validity of the proposed control scheme is demonstrated by means of simulation results.
An Automated Online Field Instrument to Quantify the Oxidative Potential of Aerosol Particles via Ascorbic Acid Oxidation

Large-scale epidemiological studies have consistently shown that exposure to ambient particulate matter (PM) is responsible for a variety of adverse health effects. However, the specific physical and chemical properties of particles that are responsible for observed health effects, as well as the underlying mechanisms of particle 15 toxicity upon exposure, remain largely uncertain. Studies have widely suggested that the oxidative potential (OP) of aerosol particles is a key metric to quantify particle toxicity. OP is defined as the ability of aerosol particle components to produce reactive oxidative species (ROS) and deplete antioxidants in vivo. Traditional methods for measuring OP using acellular assays largely rely on analyzing PM collected in filters offline. This is labor intensive and involves a substantial time delay between particle collection and OP analysis. It therefore likely underestimates 20 particle OP, because many reactive chemical components which are contributing to OP are short-lived and therefore degrade prior to offline analysis. Thus, new techniques are required to provide a robust and rapid quantification of particle OP, capturing the chemistry of oxidizing and short-lived highly reactive aerosol components and their concentration dynamics in the atmosphere. To address these measurement shortcomings, we developed a portable online instrument that directly samples particles into an ascorbic acid-based assay under 25 physiologically relevant conditions of pH 6.8 and 37 °C, providing continuous accurate OP measurements with a high time resolution (5 mins). The instrument runs autonomously for up to three days and has a detection limit of about 5
Consequences of producing DNA gyrase from a synthetic gyrBA operon in Salmonella enterica serovar Typhimurium

DNA gyrase is an essential type II topoisomerase that is composed of two subunits, GyrA and GyrB, and has an A 2 B 2 structure. Although the A and B subunits are required in equal proportions to form DNA gyrase, the gyrA and gyrB genes that encode them in Salmonella (and in many other bacteria) are at separate locations on the chromosome, are under separate transcriptional control, and are present in different copy numbers in rapidly growing bacteria. In wild- type Salmonella , gyrA is near the chromosome's replication terminus, while gyrB is near the origin. We generated a synthetic gyrBA operon at the oriC - proximal location of gyrB to test the significance of the gyrase gene position for Salmonella physiology. Although the strain producing gyrase from an operon had a modest alteration to its DNA supercoiling set points, most housekeeping functions were unaffected. However, its SPI- 2 virulence genes were expressed at a reduced level and its survival was reduced in macrophage. Our data reveal that the horizontally acquired SPI- 2 genes have a greater sensitivity to disturbance of DNA topology than the core genome and we discuss its significance in the context of Salmonella genome evolution and the gyrA and gyrB gene arrangements found in other bacteria.